Phosphodiesterase

Overview
NamePhosphodiesterase
Smed IDSMED30023210
Length (bp)2045
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Phosphodiesterase (SMED30023210) t-SNE clustered cells

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30023210) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Phosphodiesterase (SMED30023210) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30023210) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023210

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30023210SMESG000034055.1 SMESG000034048.1 dd_Smed_v4_9276_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30023210SMESG000034055.1 SMESG000034048.1 dd_Smed_v4_9276_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30023210SMESG000034055.1 SMESG000034048.1 dd_Smed_v4_9276_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30023210SMESG000034055.1 SMESG000034048.1 dd_Smed_v4_9276_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30023210SMESG000034055.1 SMESG000034048.1 dd_Smed_v4_9276_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30023210SMESG000034055.1 SMESG000034048.1 dd_Smed_v4_9276_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023210SMESG000034055.1 SMESG000034048.1 dd_Smed_v4_9276_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30023210SMESG000034055.1 SMESG000034048.1 dd_Smed_v4_9276_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023210SMESG000048991.1 SMESG000034055.1 Contig19724newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023210SMESG000048991.1 SMESG000034055.1 Contig19724uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023210SMESG000045326.1 SMESG000034055.1 SMESG000034048.1 SMESG000021912.1 Contig49369newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023210SMESG000045326.1 SMESG000034055.1 SMESG000034048.1 SMESG000021912.1 Contig49369uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783])

HSP 1 Score: 490.345 bits (1261), Expect = 5.034e-163
Identity = 263/588 (44.73%), Postives = 380/588 (64.63%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFI---------SRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEIN---FSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEH-------LDEVLFNQYNWKSGENFNLESPK--VEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP +  G  + ++     G++     L     TS G  +          RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN    +EE    + ++TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P  +++        + ++   +    S    N   P+  V+ E  ++       + +WG  +F+++  +    L  I  +I + R +    K+ + T+I +L  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:  136 LKKSRMSWPSSFQGLRRFDVDN---GTSAGRSPL--DPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 709
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783])

HSP 1 Score: 485.337 bits (1248), Expect = 7.150e-163
Identity = 251/532 (47.18%), Postives = 360/532 (67.67%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEIN---FSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEH-------LDEVLFNQYNWKSGENFNLESPK--VEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN    +EE    + ++TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P  +++        + ++   +    S    N   P+  V+ E  ++       + +WG  +F+++  +    L  I  +I + R +    K+ + T+I +L  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   57 RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 579
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4D (phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:8783])

HSP 1 Score: 484.567 bits (1246), Expect = 1.928e-162
Identity = 251/532 (47.18%), Postives = 360/532 (67.67%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEIN---FSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEH-------LDEVLFNQYNWKSGENFNLESPK--VEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN    +EE    + ++TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P  +++        + ++   +    S    N   P+  V+ E  ++       + +WG  +F+++  +    L  I  +I + R +    K+ + T+I +L  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   65 RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 587
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: AC008397.2 (cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Source:UniProtKB/Swiss-Prot;Acc:Q08493])

HSP 1 Score: 485.337 bits (1248), Expect = 2.035e-162
Identity = 260/590 (44.07%), Postives = 378/590 (64.07%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCR------GSAGAAESLKDQKFTSHGEFIS-------RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMF--QLKGKSTDSKLEDIED-DEINFSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG--ENFNLES---PKVEKEIHNMCQISEMI--LCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            L++ R SWPV+S           CR      G +    +L  Q     G  +        RR SFLYRSDS   L+ K  +R  S  S +          +D++VTPFAQ+L +LR V++ +A +   Q  G +    + +    +++  +E+T   +  +TL  L+WCL QLE +QT  SV E+A++KFKR+L++EL  + + SR+GN+ + +YI +TF+D     E+P ++ E   + + ++ +   G   + +L S   P+   +     Q+++ +    +WG D+F+++  +    L  I  SI + R +    ++   T+  +L  +E  Y +  +YHNS+HAADV QS HV+++  A + VF+DLEI +AL  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + S  Q+  +RRMVIDMVLATDMSKHM +LADLKTMVETKKV+  G+L LDNY+DRIQ+LQNL+HCADLSNPTKP+ LY QWT+R+M EFF QGD+E+E G++ SPMCD+ TASV KSQV FID+I +PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   67 LRKSRLSWPVSS-----------CRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDL--------HGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQ-VSEYISRTFLDQQTEVELPKVTAEEAPQPM-SRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQ 635
[Close]
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE4C (phosphodiesterase 4C [Source:HGNC Symbol;Acc:HGNC:8782])

HSP 1 Score: 485.337 bits (1248), Expect = 2.035e-162
Identity = 260/590 (44.07%), Postives = 378/590 (64.07%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCR------GSAGAAESLKDQKFTSHGEFIS-------RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMF--QLKGKSTDSKLEDIED-DEINFSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG--ENFNLES---PKVEKEIHNMCQISEMI--LCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            L++ R SWPV+S           CR      G +    +L  Q     G  +        RR SFLYRSDS   L+ K  +R  S  S +          +D++VTPFAQ+L +LR V++ +A +   Q  G +    + +    +++  +E+T   +  +TL  L+WCL QLE +QT  SV E+A++KFKR+L++EL  + + SR+GN+ + +YI +TF+D     E+P ++ E   + + ++ +   G   + +L S   P+   +     Q+++ +    +WG D+F+++  +    L  I  SI + R +    ++   T+  +L  +E  Y +  +YHNS+HAADV QS HV+++  A + VF+DLEI +AL  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + S  Q+  +RRMVIDMVLATDMSKHM +LADLKTMVETKKV+  G+L LDNY+DRIQ+LQNL+HCADLSNPTKP+ LY QWT+R+M EFF QGD+E+E G++ SPMCD+ TASV KSQV FID+I +PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   67 LRKSRLSWPVSS-----------CRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDL--------HGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQ-VSEYISRTFLDQQTEVELPKVTAEEAPQPM-SRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQ 635
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 464.537 bits (1194), Expect = 5.621e-156
Identity = 250/585 (42.74%), Postives = 364/585 (62.22%), Query Frame = 3 
Query:  261 PVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSH--GEFISRRNSFLYR-SDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDE-----INFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD----------EVPY----------ISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNM-------CQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            P  S     ++   +C GSA AA+ L     T        +RR SFLYR SD L      R +S  SS+   +       D++VTPFAQ+L +LR V++ L  +  ++  S DS+  +          I   ++ +    DTL  L+WCL QLE +QTHRSVSE+A+SKF+++L+KEL    ++S++G + +  ++  T+MD          EVP           ++   L +      N  SG    L +P  +  +            +    L +WGPD+F++   ++   L  +T S+L  R +F   ++  ST++ +L  +E+ YR+ N YHN IHAADV QS+HV++       VF+DLE+ +A+    +HD+DHPG TNQ+LIN+N+ LAI+YND SVLE HHLAV F L+++++C+ L + S+ Q+   R++VIDMVLATDMSKHM++LADLKTMVE KKV+G+ ++ LD YND+IQ+LQ++IH ADLSNPTKPI LY QW +R+MEE++ QGDKEKELG+E SPMCDR   ++ KSQV FID+IV+PL+ETWA+LV P+A  +L+ L ENR++Y+
Sbjct:   14 PWQSTALPSRHDHYSCAGSATAADGLGGAHLTPSLSSSVHARRESFLYRASDDLREASSLRPVSRASSIASNEH--GHGDDLIVTPFAQLLASLRNVRSNLISITNIQN-SDDSRHANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQ-VSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKISGVR-KLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRN-NHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQ 592
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 464.151 bits (1193), Expect = 1.122e-155
Identity = 250/585 (42.74%), Postives = 364/585 (62.22%), Query Frame = 3 
Query:  261 PVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSH--GEFISRRNSFLYR-SDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDE-----INFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD----------EVPY----------ISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNM-------CQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            P  S     ++   +C GSA AA+ L     T        +RR SFLYR SD L      R +S  SS+   +       D++VTPFAQ+L +LR V++ L  +  ++  S DS+  +          I   ++ +    DTL  L+WCL QLE +QTHRSVSE+A+SKF+++L+KEL    ++S++G + +  ++  T+MD          EVP           ++   L +      N  SG    L +P  +  +            +    L +WGPD+F++   ++   L  +T S+L  R +F   ++  ST++ +L  +E+ YR+ N YHN IHAADV QS+HV++       VF+DLE+ +A+    +HD+DHPG TNQ+LIN+N+ LAI+YND SVLE HHLAV F L+++++C+ L + S+ Q+   R++VIDMVLATDMSKHM++LADLKTMVE KKV+G+ ++ LD YND+IQ+LQ++IH ADLSNPTKPI LY QW +R+MEE++ QGDKEKELG+E SPMCDR   ++ KSQV FID+IV+PL+ETWA+LV P+A  +L+ L ENR++Y+
Sbjct:   26 PWQSTALPSRHDHYSCAGSATAADGLGGAHLTPSLSSSVHARRESFLYRASDDLREASSLRPVSRASSIASNEH--GHGDDLIVTPFAQLLASLRNVRSNLISITNIQN-SDDSRHANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQ-VSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKISGVR-KLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRN-NHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQ 604
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 463.766 bits (1192), Expect = 1.633e-155
Identity = 250/585 (42.74%), Postives = 364/585 (62.22%), Query Frame = 3 
Query:  261 PVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSH--GEFISRRNSFLYR-SDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDE-----INFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD----------EVPY----------ISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNM-------CQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            P  S     ++   +C GSA AA+ L     T        +RR SFLYR SD L      R +S  SS+   +       D++VTPFAQ+L +LR V++ L  +  ++  S DS+  +          I   ++ +    DTL  L+WCL QLE +QTHRSVSE+A+SKF+++L+KEL    ++S++G + +  ++  T+MD          EVP           ++   L +      N  SG    L +P  +  +            +    L +WGPD+F++   ++   L  +T S+L  R +F   ++  ST++ +L  +E+ YR+ N YHN IHAADV QS+HV++       VF+DLE+ +A+    +HD+DHPG TNQ+LIN+N+ LAI+YND SVLE HHLAV F L+++++C+ L + S+ Q+   R++VIDMVLATDMSKHM++LADLKTMVE KKV+G+ ++ LD YND+IQ+LQ++IH ADLSNPTKPI LY QW +R+MEE++ QGDKEKELG+E SPMCDR   ++ KSQV FID+IV+PL+ETWA+LV P+A  +L+ L ENR++Y+
Sbjct:   28 PWQSTALPSRHDHYSCAGSATAADGLGGAHLTPSLSSSVHARRESFLYRASDDLREASSLRPVSRASSIASNEH--GHGDDLIVTPFAQLLASLRNVRSNLISITNIQN-SDDSRHANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQ-VSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKISGVR-KLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRN-NHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQ 606
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 463.766 bits (1192), Expect = 6.205e-155
Identity = 250/585 (42.74%), Postives = 364/585 (62.22%), Query Frame = 3 
Query:  261 PVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSH--GEFISRRNSFLYR-SDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDE-----INFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD----------EVPY----------ISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNM-------CQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            P  S     ++   +C GSA AA+ L     T        +RR SFLYR SD L      R +S  SS+   +       D++VTPFAQ+L +LR V++ L  +  ++  S DS+  +          I   ++ +    DTL  L+WCL QLE +QTHRSVSE+A+SKF+++L+KEL    ++S++G + +  ++  T+MD          EVP           ++   L +      N  SG    L +P  +  +            +    L +WGPD+F++   ++   L  +T S+L  R +F   ++  ST++ +L  +E+ YR+ N YHN IHAADV QS+HV++       VF+DLE+ +A+    +HD+DHPG TNQ+LIN+N+ LAI+YND SVLE HHLAV F L+++++C+ L + S+ Q+   R++VIDMVLATDMSKHM++LADLKTMVE KKV+G+ ++ LD YND+IQ+LQ++IH ADLSNPTKPI LY QW +R+MEE++ QGDKEKELG+E SPMCDR   ++ KSQV FID+IV+PL+ETWA+LV P+A  +L+ L ENR++Y+
Sbjct:   75 PWQSTALPSRHDHYSCAGSATAADGLGGAHLTPSLSSSVHARRESFLYRASDDLREASSLRPVSRASSIASNEH--GHGDDLIVTPFAQLLASLRNVRSNLISITNIQN-SDDSRHANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQ-VSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKISGVR-KLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRN-NHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQ 653
[Close]
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 460.299 bits (1183), Expect = 1.464e-154
Identity = 247/568 (43.49%), Postives = 358/568 (63.03%), Query Frame = 3 
Query:  312 GSAGAAESLKDQKFTSH--GEFISRRNSFLYR-SDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDE-----INFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD----------EVPY----------ISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNM-------CQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            GSA AA+ L     T        +RR SFLYR SD L      R +S  SS+   +       D++VTPFAQ+L +LR V++ L  +  ++  S DS+  +          I   ++ +    DTL  L+WCL QLE +QTHRSVSE+A+SKF+++L+KEL    ++S++G + +  ++  T+MD          EVP           ++   L +      N  SG    L +P  +  +            +    L +WGPD+F++   ++   L  +T S+L  R +F   ++  ST++ +L  +E+ YR+ N YHN IHAADV QS+HV++       VF+DLE+ +A+    +HD+DHPG TNQ+LIN+N+ LAI+YND SVLE HHLAV F L+++++C+ L + S+ Q+   R++VIDMVLATDMSKHM++LADLKTMVE KKV+G+ ++ LD YND+IQ+LQ++IH ADLSNPTKPI LY QW +R+MEE++ QGDKEKELG+E SPMCDR   ++ KSQV FID+IV+PL+ETWA+LV P+A  +L+ L ENR++Y+
Sbjct:   18 GSATAADGLGGAHLTPSLSSSVHARRESFLYRASDDLREASSLRPVSRASSIASNEH--GHGDDLIVTPFAQLLASLRNVRSNLISITNIQN-SDDSRHANRSAKRPPLHNIELPDDVVHCAHDTLEELDWCLDQLETIQTHRSVSEMASSKFRKMLNKELSHFAESSKSGTQ-VSKFLITTYMDKEEDEPSIEIEVPTEVQGPSTSGPMTLSILKKAQTAAMNKISGVR-KLRAPSHDGHVPEYGVNCAREIAVHMQRLDDWGPDVFKIDELSKNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRN-NHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENREWYQ 579
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0333317)

HSP 1 Score: 469.929 bits (1208), Expect = 1.369e-156
Identity = 256/573 (44.68%), Postives = 363/573 (63.35%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKS-------SVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGK---------STDSKLEDIEDDEINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLF----------NQY------------------------NWKSGE---NFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   ++ K  +R  S  S       +   VD++    +D++VTPFAQIL +LR V+  L  +  +            S+ S+  +     ++  EE    + TDT+  L+WCL QLE +QTHRSVS++A+ KFKR+L+KEL    ++SR+GN+ I +YIC TF+D     ++P +  E   E++            QY                        N  +GE    F +E+P+ E E+  +  + E  L  WG  IF +   +    L  +  +I ++R++ ++L +   T +NF+  +E+ Y   N +HNS+HAADV QS +V+++  A + VF+ LE+  AL  A IHD+DHPG+TNQFL+N++  LA++YND SVLENHHLAV F L++N  C+I  +  K Q+Q +R+MVID+VL+TDMSKHM++LADLKTMVETKKV+GSG+L LDNY DRIQ+L+NL+HCADLSNPTKP+ LY +W   +MEEFF QGDKE+E G++ SPMCDR  A++ KSQV FID+IV+PLWETWA+LV P+A  +L+ L ENR YY+
Sbjct:   60 RRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRS--HGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQ-ISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPR-ENELGTL--LGE--LDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 624
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0333316)

HSP 1 Score: 469.929 bits (1208), Expect = 1.369e-156
Identity = 256/573 (44.68%), Postives = 363/573 (63.35%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKS-------SVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGK---------STDSKLEDIEDDEINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLF----------NQY------------------------NWKSGE---NFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   ++ K  +R  S  S       +   VD++    +D++VTPFAQIL +LR V+  L  +  +            S+ S+  +     ++  EE    + TDT+  L+WCL QLE +QTHRSVS++A+ KFKR+L+KEL    ++SR+GN+ I +YIC TF+D     ++P +  E   E++            QY                        N  +GE    F +E+P+ E E+  +  + E  L  WG  IF +   +    L  +  +I ++R++ ++L +   T +NF+  +E+ Y   N +HNS+HAADV QS +V+++  A + VF+ LE+  AL  A IHD+DHPG+TNQFL+N++  LA++YND SVLENHHLAV F L++N  C+I  +  K Q+Q +R+MVID+VL+TDMSKHM++LADLKTMVETKKV+GSG+L LDNY DRIQ+L+NL+HCADLSNPTKP+ LY +W   +MEEFF QGDKE+E G++ SPMCDR  A++ KSQV FID+IV+PLWETWA+LV P+A  +L+ L ENR YY+
Sbjct:   60 RRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRS--HGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQ-ISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPR-ENELGTL--LGE--LDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 624
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070520)

HSP 1 Score: 472.626 bits (1215), Expect = 1.934e-156
Identity = 253/563 (44.94%), Postives = 361/563 (64.12%), Query Frame = 3 
Query:  378 RRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGK---------STDSKLEDIEDDEINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLF----------NQY------------------------NWKSGE---NFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS + +   + +S  SS+     + +  +D++VTPFAQIL +LR V+  L  +  +            S+ S+  +     ++  EE    + TDT+  L+WCL QLE +QTHRSVS++A+ KFKR+L+KEL    ++SR+GN+ I +YIC TF+D     ++P +  E   E++            QY                        N  +GE    F +E+P+ E E+  +  + E  L  WG  IF +   +    L  +  +I ++R++ ++L +   T +NF+  +E+ Y   N +HNS+HAADV QS +V+++  A + VF+ LE+  AL  A IHD+DHPG+TNQFL+N++  LA++YND SVLENHHLAV F L++N  C+I  +  K Q+Q +R+MVID+VL+TDMSKHM++LADLKTMVETKKV+GSG+L LDNY DRIQ+L+NL+HCADLSNPTKP+ LY +W   +MEEFF QGDKE+E G++ SPMCDR  A++ KSQV FID+IV+PLWETWA+LV P+A  +L+ L ENR YY+
Sbjct:  172 RRESFLYRSDS-DFEMSPKSMSRNSSIA----SESHGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQ-ISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPR-ENELGTL--LGE--LDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 723
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070517)

HSP 1 Score: 468.389 bits (1204), Expect = 3.454e-156
Identity = 256/573 (44.68%), Postives = 363/573 (63.35%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKS-------SVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGK---------STDSKLEDIEDDEINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLF----------NQY------------------------NWKSGE---NFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   ++ K  +R  S  S       +   VD++    +D++VTPFAQIL +LR V+  L  +  +            S+ S+  +     ++  EE    + TDT+  L+WCL QLE +QTHRSVS++A+ KFKR+L+KEL    ++SR+GN+ I +YIC TF+D     ++P +  E   E++            QY                        N  +GE    F +E+P+ E E+  +  + E  L  WG  IF +   +    L  +  +I ++R++ ++L +   T +NF+  +E+ Y   N +HNS+HAADV QS +V+++  A + VF+ LE+  AL  A IHD+DHPG+TNQFL+N++  LA++YND SVLENHHLAV F L++N  C+I  +  K Q+Q +R+MVID+VL+TDMSKHM++LADLKTMVETKKV+GSG+L LDNY DRIQ+L+NL+HCADLSNPTKP+ LY +W   +MEEFF QGDKE+E G++ SPMCDR  A++ KSQV FID+IV+PLWETWA+LV P+A  +L+ L ENR YY+
Sbjct:   46 RRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRS--HGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQ-ISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPR-ENELGTL--LGE--LDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 610
[Close]
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0333314)

HSP 1 Score: 468.389 bits (1204), Expect = 3.708e-156
Identity = 256/573 (44.68%), Postives = 363/573 (63.35%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKS-------SVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGK---------STDSKLEDIEDDEINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLF----------NQY------------------------NWKSGE---NFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   ++ K  +R  S  S       +   VD++    +D++VTPFAQIL +LR V+  L  +  +            S+ S+  +     ++  EE    + TDT+  L+WCL QLE +QTHRSVS++A+ KFKR+L+KEL    ++SR+GN+ I +YIC TF+D     ++P +  E   E++            QY                        N  +GE    F +E+P+ E E+  +  + E  L  WG  IF +   +    L  +  +I ++R++ ++L +   T +NF+  +E+ Y   N +HNS+HAADV QS +V+++  A + VF+ LE+  AL  A IHD+DHPG+TNQFL+N++  LA++YND SVLENHHLAV F L++N  C+I  +  K Q+Q +R+MVID+VL+TDMSKHM++LADLKTMVETKKV+GSG+L LDNY DRIQ+L+NL+HCADLSNPTKP+ LY +W   +MEEFF QGDKE+E G++ SPMCDR  A++ KSQV FID+IV+PLWETWA+LV P+A  +L+ L ENR YY+
Sbjct:   48 RRESFLYRSDSDFEMSPKSMSRNSSIASERFKEQEASILVDRS--HGEDLIVTPFAQILASLRSVRNNLLSLTNVPASNKSRRPNQSSSASRSGNPPGAPLSQGEEAYTRLATDTIEELDWCLDQLETIQTHRSVSDMASLKFKRMLNKELSHFSESSRSGNQ-ISEYICSTFLDKQQEFDLPSLRVEDNPELVAANAAAGQQSAGQYARSRSPRGPPMSQISGVKRPLSHTNSFTGERLPTFGVETPR-ENELGTL--LGE--LDTWGIQIFSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEENRDYYQ 612
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4d (phosphodiesterase 4D, cAMP-specific [Source:ZFIN;Acc:ZDB-GENE-081105-16])

HSP 1 Score: 487.263 bits (1253), Expect = 6.213e-164
Identity = 253/534 (47.38%), Postives = 361/534 (67.60%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDD----EINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  ++ + +++K   + +     + +++EE    + T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D     E+P    +   E      +  SG           N N+    V+ E  +        + +WG ++F++S  +    L  +  +I + R +    K+ + T I +L  +E+ Y +  +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   36 RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFAALTNVQQERSNNKRSPMCNPPPITKTSYTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISSTFLDKQNEVEMPSPQSQKDKEKKKRPMSQISGVKKLTHSSSLTNSNIPRFGVKTETEDELAKELEDVNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 560
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4d (phosphodiesterase 4D, cAMP-specific [Source:ZFIN;Acc:ZDB-GENE-081105-16])

HSP 1 Score: 488.034 bits (1255), Expect = 1.089e-163
Identity = 253/534 (47.38%), Postives = 361/534 (67.60%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDD----EINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  ++ + +++K   + +     + +++EE    + T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D     E+P    +   E      +  SG           N N+    V+ E  +        + +WG ++F++S  +    L  +  +I + R +    K+ + T I +L  +E+ Y +  +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   55 RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFAALTNVQQERSNNKRSPMCNPPPITKTSYTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISSTFLDKQNEVEMPSPQSQKDKEKKKRPMSQISGVKKLTHSSSLTNSNIPRFGVKTETEDELAKELEDVNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 579
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: BX510928.2 (phosphodiesterase 4D, cAMP-specific [Source:NCBI gene;Acc:566998])

HSP 1 Score: 487.649 bits (1254), Expect = 1.186e-163
Identity = 252/529 (47.64%), Postives = 356/529 (67.30%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  ++ + +++K + +    +   E      T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D     E+P    +   E      +  SG           N N+    V+ E  +        + +WG ++F++S  +    L  +  +I + R +    K+ + T I +L  +E+ Y +  +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   55 RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFAALTNVQQERSNNKSDRLPP-SLPPEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISSTFLDKQNEVEMPSPQSQKDKEKKKRPMSQISGVKKLTHSSSLTNSNIPRFGVKTETEDELAKELEDVNKWGLNVFKVSEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHADVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 573
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4ca (phosphodiesterase 4C, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-070912-373])

HSP 1 Score: 482.641 bits (1241), Expect = 1.104e-161
Identity = 269/624 (43.11%), Postives = 395/624 (63.30%), Query Frame = 3 
Query:  183 NWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQ--KNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLES-PKVEKEIH--NMCQIS----------EMILCE-------WGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYEKXXXXXXXXXXXXXTVILNYGNKL 1976
            NW   +   P +  +PI + + R  + V  NG +        + S G+   L  Q    H +   RR SFLYRSDS   L+ K  +R  S  S +          +D++VTPFAQ+L +LR V++  A +   + +   +  E I +  + F+EE    +  +TL  L+WCL QLE ++T  SVSE+A++KFKR+L++EL Q  + S++GN+ + +YI  TF+++      +H  +++      K  +   +     V+K  H  N+   S          E +L +       WG D+F++S  +    L     +  + R +  + K+ + T IN++ A+E +YRS  +YHNSIHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVIDMVLATDMSKHM +LADLKTMVETKKV+  G+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+M EFF+QGD+E++ G+E SPMCD+  AS+ KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+ +   + ++  E  + I + G+K 
Sbjct:   21 NW--NLYGSPCAVNRPIDIVQKRRRFDV-ENGLSVGRSPLDSQASPGSGLVL--QANFPHSQ---RRESFLYRSDSDFDLSPKAMSRNSSTASEL--------HGEDMIVTPFAQVLASLRTVRSNFAVLTHQQDRVPSNGHEYI-NVLLYFAEEPFQKLAVETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSETSKSGNQ-VSEYISSTFLEK------QHDMDIMSTPSKEKEKKKRPMSQISGVKKPTHSSNIAPSSIPRFGVSTNREDLLAKELEDFDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPHSPTSTPEDKSGIASAGDKF 620
[Close]
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde4ca (phosphodiesterase 4C, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-070912-373])

HSP 1 Score: 482.641 bits (1241), Expect = 1.104e-161
Identity = 269/624 (43.11%), Postives = 395/624 (63.30%), Query Frame = 3 
Query:  183 NWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQ--KNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLES-PKVEKEIH--NMCQIS----------EMILCE-------WGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYEKXXXXXXXXXXXXXTVILNYGNKL 1976
            NW   +   P +  +PI + + R  + V  NG +        + S G+   L  Q    H +   RR SFLYRSDS   L+ K  +R  S  S +          +D++VTPFAQ+L +LR V++  A +   + +   +  E I +  + F+EE    +  +TL  L+WCL QLE ++T  SVSE+A++KFKR+L++EL Q  + S++GN+ + +YI  TF+++      +H  +++      K  +   +     V+K  H  N+   S          E +L +       WG D+F++S  +    L     +  + R +  + K+ + T IN++ A+E +YRS  +YHNSIHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVIDMVLATDMSKHM +LADLKTMVETKKV+  G+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+M EFF+QGD+E++ G+E SPMCD+  AS+ KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+ +   + ++  E  + I + G+K 
Sbjct:   21 NW--NLYGSPCAVNRPIDIVQKRRRFDV-ENGLSVGRSPLDSQASPGSGLVL--QANFPHSQ---RRESFLYRSDSDFDLSPKAMSRNSSTASEL--------HGEDMIVTPFAQVLASLRTVRSNFAVLTHQQDRVPSNGHEYI-NVLLYFAEEPFQKLAVETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSETSKSGNQ-VSEYISSTFLEK------QHDMDIMSTPSKEKEKKKRPMSQISGVKKPTHSSNIAPSSIPRFGVSTNREDLLAKELEDFDRWGVDMFKISECSGNRPLTVAMYTTFQERDLLKSFKIPVDTFINYMTALEENYRSDVAYHNSIHAADVVQSTHVLLSTPALEAVFTDLEILAAMFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRQWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNREWYQSMIPHSPTSTPEDKSGIASAGDKF 620
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: plxnb1 (plexin B1 [Source:Xenbase;Acc:XB-GENE-856606])

HSP 1 Score: 488.804 bits (1257), Expect = 1.793e-163
Identity = 265/543 (48.80%), Postives = 365/543 (67.22%), Query Frame = 3 
Query:  351 FTSHGEFISRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEIN---FSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYIS----EEHLDEVLFNQYNW-------KSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            FTSH +   RR SFLYRSDS   L+ K  +R  SA S             D++VTPFAQ+L +LR V+     +  + G      LE++E D ++   F+E++   +  DTL  L+WCL QLE +QT+RSVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D     E+P  +    E+   + L  Q +         S  N ++    V+ E  +M       L +WG +IF++++ +    L  I  +I + R +    K+   T+I +   +E+ Y S  +YHNS+HAADV QS HV++S  A   VF+DLEI +A+  A IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++   C+I  + +K Q+Q +R+MVIDMVLATDMSKHM++LADLKTMVETKKV+ SG+L LDNY DRIQ+L+N++HCADLSNPTK + LY QWT+R+MEEFF QGDKE+E G+E SPMCD+ TASV KSQV FID+IV+PLWETWA+LVQP+A  +L+ L +NR +Y+
Sbjct:  122 FTSHNQ---RRESFLYRSDSDYDLSPKTMSRNSSAASE--------QHGDDLIVTPFAQVLASLRSVRNNFTVLTNVHGT-----LEELEPDYMSMCLFAEDSYQKIAMDTLEELDWCLDQLETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISSTFLDKQNDVEIPSPTQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSMSRFGVKTEYEDMLSKELEDLNKWGLNIFKVASYSCNRPLTCIMYAIFQERDLLKTFKIPADTLITYTMTLEDHYHSDVAYHNSLHAADVTQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFQNLTKKQRQSLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQ 647
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 487.263 bits (1253), Expect = 2.154e-163
Identity = 267/593 (45.03%), Postives = 380/593 (64.08%), Query Frame = 3 
Query:  210 PTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFI--SRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPS------VTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMDE-------VPYISEEHLDEVLFNQYNW-------KSGENFNLESPKVEKEIHNMCQISEM-ILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            P +  KPI +K+ R  + V  NG            S G+   L+         F+   RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN  + T+P         +TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D+        P   E+   +   +Q +         S  N N+    V+ E +  C   E+  + +WG +IF+++  +    L  +  +I + R+M    K+ + T+I +L  +E+ Y +  +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q++R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY  WT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   27 PYAINKPIDIKQQRKRFDV-DNGTTSGRSPLDPMTSPGSGLILQ-------ANFVHSQRRESFLYRSDSDYELSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSIN--KATIPEEAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISNTFLDKQHEVEMPSPAQKEKEKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKSE-NEECLAKELEDVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 599
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 486.108 bits (1250), Expect = 3.722e-163
Identity = 254/535 (47.48%), Postives = 360/535 (67.29%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPS------VTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMDE-------VPYISEEHLDEVLFNQYNW-------KSGENFNLESPKVEKEIHNMCQISEM-ILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN  + T+P         +TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D+        P   E+   +   +Q +         S  N N+    V+ E +  C   E+  + +WG +IF+++  +    L  +  +I + R+M    K+ + T+I +L  +E+ Y +  +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q++R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY  WT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   57 RRESFLYRSDSDYELSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSIN--KATIPEEAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISNTFLDKQHEVEMPSPAQKEKEKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKSE-NEECLAKELEDVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 579
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 485.337 bits (1248), Expect = 6.552e-163
Identity = 254/535 (47.48%), Postives = 360/535 (67.29%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPS------VTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMDE-------VPYISEEHLDEVLFNQYNW-------KSGENFNLESPKVEKEIHNMCQISEM-ILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN  + T+P         +TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D+        P   E+   +   +Q +         S  N N+    V+ E +  C   E+  + +WG +IF+++  +    L  +  +I + R+M    K+ + T+I +L  +E+ Y +  +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q++R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY  WT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   62 RRESFLYRSDSDYELSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSIN--KATIPEEAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISNTFLDKQHEVEMPSPAQKEKEKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKSE-NEECLAKELEDVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 584
[Close]
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 484.952 bits (1247), Expect = 1.194e-162
Identity = 254/535 (47.48%), Postives = 360/535 (67.29%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPS------VTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMDE-------VPYISEEHLDEVLFNQYNW-------KSGENFNLESPKVEKEIHNMCQISEM-ILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN  + T+P         +TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D+        P   E+   +   +Q +         S  N N+    V+ E +  C   E+  + +WG +IF+++  +    L  +  +I + R+M    K+ + T+I +L  +E+ Y +  +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q++R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY  WT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   65 RRESFLYRSDSDYELSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSTMCNQPSIN--KATIPEEAYQKLAGETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISNTFLDKQHEVEMPSPAQKEKEKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKSE-NEECLAKELEDVNKWGLNIFKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 587
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555])

HSP 1 Score: 489.574 bits (1259), Expect = 4.514e-163
Identity = 264/588 (44.90%), Postives = 380/588 (64.63%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFI---------SRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEIN---FSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEH-------LDEVLFNQYNWKSGENFNLESPK--VEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP +  G  + ++     G++     L     TS G  +          RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN    +EE    + ++TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D     E+P  +++        + ++   +    S    N   P+  V+ E  ++       + +WG  +F+++  +    L  I  +I + R +    K+ + T+I +L  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:  131 LKKSRMSWPSSFQGLRRFDVDN---GTSAGRSPL--DPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 704
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4c (phosphodiesterase 4C, cAMP specific [Source:MGI Symbol;Acc:MGI:99556])

HSP 1 Score: 484.182 bits (1245), Expect = 6.680e-163
Identity = 245/533 (45.97%), Postives = 351/533 (65.85%), Query Frame = 3 
Query:  372 ISRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPS-------VTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSGENFNLES---PKVEKEIHNMCQISEMI--LCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            + RR SFLYRSDS    + K  +R  SA S +          +D++VTPFAQ+L +LR V+  +A +    G +T   L        + S++  P+       V +TL  L+WCL QLE +QT RSV E+A++KFKR+L++EL  + + SR+GN+ + +YI QTF+D     E+P    E     +      +   + +L +   P+   +     Q+++ +    +WG D+F+++  +    L  +  S+ + R +    ++   T++ +L  +E  Y S  +YHNS+HAADVVQS HV++   A + VF+DLE+ +A+    IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + S  Q+  +RRMVIDMVLATDMSKHM++LADLKTMVETKKV+  G+L LDNY+DRIQ+LQ+L+HCADLSNP KP+ LY QWTER+M EFF QGD+E+E G++ SPMCD+ TAS+ KSQV FID+I  PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   76 VQRRESFLYRSDSDHEPSPKAVSRTSSAASDL--------HGEDMIVTPFAQVLASLRTVRNNVAALAHGPGSATRQVLLGTPP---HSSQQAAPTEDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELSYLSETSRSGNQ-VSEYISQTFLDQQAEVELPQPPTEDDPWPMAQITELRRSSHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQ 596
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4c (phosphodiesterase 4C, cAMP specific [Source:MGI Symbol;Acc:MGI:99556])

HSP 1 Score: 484.182 bits (1245), Expect = 6.680e-163
Identity = 245/533 (45.97%), Postives = 351/533 (65.85%), Query Frame = 3 
Query:  372 ISRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPS-------VTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSGENFNLES---PKVEKEIHNMCQISEMI--LCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            + RR SFLYRSDS    + K  +R  SA S +          +D++VTPFAQ+L +LR V+  +A +    G +T   L        + S++  P+       V +TL  L+WCL QLE +QT RSV E+A++KFKR+L++EL  + + SR+GN+ + +YI QTF+D     E+P    E     +      +   + +L +   P+   +     Q+++ +    +WG D+F+++  +    L  +  S+ + R +    ++   T++ +L  +E  Y S  +YHNS+HAADVVQS HV++   A + VF+DLE+ +A+    IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + S  Q+  +RRMVIDMVLATDMSKHM++LADLKTMVETKKV+  G+L LDNY+DRIQ+LQ+L+HCADLSNP KP+ LY QWTER+M EFF QGD+E+E G++ SPMCD+ TAS+ KSQV FID+I  PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   76 VQRRESFLYRSDSDHEPSPKAVSRTSSAASDL--------HGEDMIVTPFAQVLASLRTVRNNVAALAHGPGSATRQVLLGTPP---HSSQQAAPTEDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELSYLSETSRSGNQ-VSEYISQTFLDQQAEVELPQPPTEDDPWPMAQITELRRSSHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQ 596
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4d (phosphodiesterase 4D, cAMP specific [Source:MGI Symbol;Acc:MGI:99555])

HSP 1 Score: 484.567 bits (1246), Expect = 1.244e-162
Identity = 252/532 (47.37%), Postives = 360/532 (67.67%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEIN---FSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEH-------LDEVLFNQYNWKSGENFNLESPK--VEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN    +EE    + ++TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D     E+P  +++        + ++   +    S    N   P+  V+ E  ++       + +WG  +F+++  +    L  I  +I + R +    K+ + T+I +L  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   57 RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 579
[Close]
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde4c (phosphodiesterase 4C, cAMP specific [Source:MGI Symbol;Acc:MGI:99556])

HSP 1 Score: 484.567 bits (1246), Expect = 1.312e-162
Identity = 245/533 (45.97%), Postives = 351/533 (65.85%), Query Frame = 3 
Query:  372 ISRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPS-------VTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSGENFNLES---PKVEKEIHNMCQISEMI--LCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            + RR SFLYRSDS    + K  +R  SA S +          +D++VTPFAQ+L +LR V+  +A +    G +T   L        + S++  P+       V +TL  L+WCL QLE +QT RSV E+A++KFKR+L++EL  + + SR+GN+ + +YI QTF+D     E+P    E     +      +   + +L +   P+   +     Q+++ +    +WG D+F+++  +    L  +  S+ + R +    ++   T++ +L  +E  Y S  +YHNS+HAADVVQS HV++   A + VF+DLE+ +A+    IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + S  Q+  +RRMVIDMVLATDMSKHM++LADLKTMVETKKV+  G+L LDNY+DRIQ+LQ+L+HCADLSNP KP+ LY QWTER+M EFF QGD+E+E G++ SPMCD+ TAS+ KSQV FID+I  PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:  116 VQRRESFLYRSDSDHEPSPKAVSRTSSAASDL--------HGEDMIVTPFAQVLASLRTVRNNVAALAHGPGSATRQVLLGTPP---HSSQQAAPTEDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELSYLSETSRSGNQ-VSEYISQTFLDQQAEVELPQPPTEDDPWPMAQITELRRSSHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQ 636
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q08499|PDE4D_HUMAN (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens OX=9606 GN=PDE4D PE=1 SV=2)

HSP 1 Score: 490.345 bits (1261), Expect = 2.417e-162
Identity = 263/588 (44.73%), Postives = 380/588 (64.63%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFI---------SRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEIN---FSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEH-------LDEVLFNQYNWKSGENFNLESPK--VEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP +  G  + ++     G++     L     TS G  +          RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN    +EE    + ++TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P  +++        + ++   +    S    N   P+  V+ E  ++       + +WG  +F+++  +    L  I  +I + R +    K+ + T+I +L  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:  136 LKKSRMSWPSSFQGLRRFDVDN---GTSAGRSPL--DPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 709
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q3UEI1|PDE4C_MOUSE (cAMP-specific 3',5'-cyclic phosphodiesterase 4C OS=Mus musculus OX=10090 GN=Pde4c PE=1 SV=1)

HSP 1 Score: 484.567 bits (1246), Expect = 9.174e-162
Identity = 245/533 (45.97%), Postives = 351/533 (65.85%), Query Frame = 3 
Query:  372 ISRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPS-------VTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSGENFNLES---PKVEKEIHNMCQISEMI--LCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            + RR SFLYRSDS    + K  +R  SA S +          +D++VTPFAQ+L +LR V+  +A +    G +T   L        + S++  P+       V +TL  L+WCL QLE +QT RSV E+A++KFKR+L++EL  + + SR+GN+ + +YI QTF+D     E+P    E     +      +   + +L +   P+   +     Q+++ +    +WG D+F+++  +    L  +  S+ + R +    ++   T++ +L  +E  Y S  +YHNS+HAADVVQS HV++   A + VF+DLE+ +A+    IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + S  Q+  +RRMVIDMVLATDMSKHM++LADLKTMVETKKV+  G+L LDNY+DRIQ+LQ+L+HCADLSNP KP+ LY QWTER+M EFF QGD+E+E G++ SPMCD+ TAS+ KSQV FID+I  PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:  116 VQRRESFLYRSDSDHEPSPKAVSRTSSAASDL--------HGEDMIVTPFAQVLASLRTVRNNVAALAHGPGSATRQVLLGTPP---HSSQQAAPTEDSGLQLVQETLEELDWCLEQLETLQTRRSVGEMASNKFKRMLNRELSYLSETSRSGNQ-VSEYISQTFLDQQAEVELPQPPTEDDPWPMAQITELRRSSHTSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAVIFSVFQERDLLKTFQIPADTLLAYLLTLEGHYHSDVAYHNSMHAADVVQSAHVLLGTPALEAVFTDLEVLAAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFRNLSTKQRLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQSLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASMEKSQVGFIDYIAQPLWETWADLVHPDAQELLDTLEDNREWYQ 636
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q08493|PDE4C_HUMAN (cAMP-specific 3',5'-cyclic phosphodiesterase 4C OS=Homo sapiens OX=9606 GN=PDE4C PE=1 SV=2)

HSP 1 Score: 485.337 bits (1248), Expect = 9.771e-162
Identity = 260/590 (44.07%), Postives = 378/590 (64.07%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCR------GSAGAAESLKDQKFTSHGEFIS-------RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMF--QLKGKSTDSKLEDIED-DEINFSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG--ENFNLES---PKVEKEIHNMCQISEMI--LCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            L++ R SWPV+S           CR      G +    +L  Q     G  +        RR SFLYRSDS   L+ K  +R  S  S +          +D++VTPFAQ+L +LR V++ +A +   Q  G +    + +    +++  +E+T   +  +TL  L+WCL QLE +QT  SV E+A++KFKR+L++EL  + + SR+GN+ + +YI +TF+D     E+P ++ E   + + ++ +   G   + +L S   P+   +     Q+++ +    +WG D+F+++  +    L  I  SI + R +    ++   T+  +L  +E  Y +  +YHNS+HAADV QS HV+++  A + VF+DLEI +AL  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + S  Q+  +RRMVIDMVLATDMSKHM +LADLKTMVETKKV+  G+L LDNY+DRIQ+LQNL+HCADLSNPTKP+ LY QWT+R+M EFF QGD+E+E G++ SPMCD+ TASV KSQV FID+I +PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   67 LRKSRLSWPVSS-----------CRRFDLENGLSCGRRALDPQSSPGLGRIMQAPVPHSQRRESFLYRSDSDYELSPKAMSRNSSVASDL--------HGEDMIVTPFAQVLASLRTVRSNVAALARQQCLGAAKQGPVGNPSSSNQLPPAEDTGQKLALETLDELDWCLDQLETLQTRHSVGEMASNKFKRILNRELTHLSETSRSGNQ-VSEYISRTFLDQQTEVELPKVTAEEAPQPM-SRISGLHGLCHSASLSSATVPRFGVQTDQEEQLAKELEDTNKWGLDVFKVAELSGNRPLTAIIFSIFQERDLLKTFQIPADTLATYLLMLEGHYHANVAYHNSLHAADVAQSTHVLLATPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQAENCDIFQNLSAKQRLSLRRMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNLVHCADLSNPTKPLPLYRQWTDRIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVGFIDYIAHPLWETWADLVHPDAQDLLDTLEDNREWYQ 635
[Close]
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P14270|PDE4D_RAT (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Rattus norvegicus OX=10116 GN=Pde4d PE=1 SV=4)

HSP 1 Score: 488.419 bits (1256), Expect = 1.173e-161
Identity = 263/588 (44.73%), Postives = 379/588 (64.46%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFI---------SRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEIN---FSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEH-------LDEVLFNQYNWKSGENFNLESPK--VEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP +  G  + ++     G++     L     TS G  +          RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN    +EE    + ++TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D     E+P  +++        + ++   +    S    N   P+  V+ E  ++       + +WG  +F+++  +    L  I  +I + R +    K+ + T+I +L  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+M ID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:  131 LKKSRMSWPSSFQGLRRFDVDN---GTSAGRSPL--DPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 704
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BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q01063|PDE4D_MOUSE (cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Mus musculus OX=10090 GN=Pde4d PE=1 SV=2)

HSP 1 Score: 484.952 bits (1247), Expect = 4.271e-161
Identity = 252/532 (47.37%), Postives = 360/532 (67.67%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEIN---FSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEH-------LDEVLFNQYNWKSGENFNLESPK--VEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++   +        IN    +EE    + ++TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D     E+P  +++        + ++   +    S    N   P+  V+ E  ++       + +WG  +F+++  +    L  I  +I + R +    K+ + T+I +L  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:  126 RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 648
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A4W6C422 (Phosphodiesterase OS=Lates calcarifer OX=8187 GN=LOC108878161 PE=3 SV=1)

HSP 1 Score: 492.271 bits (1266), Expect = 1.248e-162
Identity = 266/588 (45.24%), Postives = 374/588 (63.61%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNI-------RETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDD----EINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP +  G  + ++       R      A     L  Q    H +   RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+     +  L+     +K   + +     +  F+EE    + T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P    +   E      +  SG           N N+    V+ E  +        + +WG ++F++S  +    L  +  +I + R +    K+ + T I +L  +E+ Y    +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LVQP+A  +L+ L +NR++Y+
Sbjct:   68 LKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQ---RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFGALTNLQQDRASNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISSTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGNRPLTVMMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNREWYQ 643
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A3B3R0M0 (Phosphodiesterase OS=Paramormyrops kingsleyae OX=1676925 PE=3 SV=1)

HSP 1 Score: 496.123 bits (1276), Expect = 1.315e-162
Identity = 264/588 (44.90%), Postives = 378/588 (64.29%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFIS-------RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDD----EINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP +  G  + ++     G++     L        G  +        RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+     SK   + +     + +F+EE    + T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P    +   +      +  SG           N N+    V+ E  ++       + +WG ++F+++  +    L  +  +I + R +    K+ + T I +L  +E+ Y    +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q++R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+ TASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   85 LKKSRMSWPSSFQGLRRFDVD---NGTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYELSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFAALTNLQQDRASSKRSPMCNQPPITKPSFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISSTFLDKQHEVEMPSPQTQKDKDKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKTEAEDLLAKELEDVNKWGLNVFKVTEFSGNRPLTVLMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDALEDNREWYQ 660
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A3B3R0F0 (Phosphodiesterase OS=Paramormyrops kingsleyae OX=1676925 PE=3 SV=1)

HSP 1 Score: 493.812 bits (1270), Expect = 1.529e-162
Identity = 269/593 (45.36%), Postives = 380/593 (64.08%), Query Frame = 3 
Query:  210 PTSKRKPIILKRGRSSWPV---TSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDD----EINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            P +  KPI +K  R  + V   TS+G      R      A     L  Q    H +   RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+     SK   + +     + +F+EE    + T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P    +   +      +  SG           N N+    V+ E  ++       + +WG ++F+++  +    L  +  +I + R +    K+ + T I +L  +E+ Y    +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q++R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+ TASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   27 PYATHKPIDIKPRRKCFDVDNGTSSG------RSPLDPMASPGSGLILQANFVHSQ---RRESFLYRSDSDYELSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFAALTNLQQDRASSKRSPMCNQPPITKPSFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISSTFLDKQHEVEMPSPQTQKDKDKKKRPMSQISGVKKLMHSSSLTNSNIPRFGVKTEAEDLLAKELEDVNKWGLNVFKVTEFSGNRPLTVLMYTIFQERDLLKTFKIPLDTFITYLMTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDALEDNREWYQ 601
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1A8N8D9 (Phosphodiesterase (Fragment) OS=Nothobranchius rachovii OX=451742 GN=PDE4D PE=3 SV=1)

HSP 1 Score: 491.5 bits (1264), Expect = 1.682e-162
Identity = 266/588 (45.24%), Postives = 375/588 (63.78%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNI-------RETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDD----EINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP +  G  + ++       R      A     L  Q    H +   RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+     +  L+   T +K   + +     +  F+EE    + T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P    +   E      +  SG           N N+    V+ E  +        + +WG ++F++S  +    L  +  +I + R +    K+ + T I +L  +E+ Y S  +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+  ASV K+QV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   23 LKKSRMSWPSSFQGLRRFDVDNGTSSGRSPLDPMASPGSGLILQANFVHSQ---RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFGALTNLQQDRTSNKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISNTFLDKQHEVEMPSPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKISEFSGSRPLTVMMHTIFQERDLLKTFKIPLDTFITYLMTLEDHYHSDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKNQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 598
[Close]
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3FY00 (Phosphodiesterase OS=Dipodomys ordii OX=10020 GN=Pde4d PE=3 SV=1)

HSP 1 Score: 492.271 bits (1266), Expect = 2.597e-162
Identity = 264/588 (44.90%), Postives = 381/588 (64.80%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFI---------SRRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEIN---FSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEH-------LDEVLFNQYNWKSGENFNLESPK--VEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP +  G  + ++     G++     L     TS G  +          RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+   A +  L+ ++ + +        IN    +EE    + ++TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + +YI  TF+D     E+P  +++        + ++   +    S    N   P+  V+ E  ++       + +WG  +F+++  +    L  I  +I + R +    K+ + T+I +L  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFF QGD+E+E G+E SPMCD+  ASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   16 LKKSRMSWPSSFQGLRRFDVD---NGTSSGRSPL--DPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DLIVTPFAQVLASLRTVRNNFAALTNLQDRAPNKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 589
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 489.574 bits (1259), Expect = 4.490e-164
Identity = 265/592 (44.76%), Postives = 372/592 (62.84%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFIS-------RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEI---NFSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQ--KNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWK----------SGENFNLESPKVEKEIHNMCQIS---EMILCE-------WGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP + +       R        A  +L  Q   S G  +        RR SFLYRSDS   L+ K  +R  S  S +          +D++VTPFAQ+L +LR V++  A +  L+ +    +        +   +  ++T P +  +TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL Q  + SR+GN+ + ++I  TF+++      +H  E+L      K          SG      SP +         +S   E +L +       WG DIF+++  +    L  I  SI + R +  + K+   T I F+  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +AL  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + SK Q+Q +R+MVIDMVLATDMSKHM  LADLKTMVETKKV+  G+L LDNY+DRIQ+LQN++HCADLSNPTKP+ +Y QWT+R+M E+F+QGD+E++ G+E SPMCD+ TASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   55 LKKPRMSWPSSFHK------RFDVENGLSAGRALDPQVSPSSGLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASEL--------HGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQ-VSEFIASTFLEK------QHDVEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVEDINRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 625
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 487.263 bits (1253), Expect = 6.304e-163
Identity = 265/595 (44.54%), Postives = 372/595 (62.52%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFIS-------RRNSFLYRSDS---LNSKYFTRGISAKSSV------CHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEI---NFSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQ--KNSRNGNKNICDYICQTFMDE-------VPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQIS---EMILCE-------WGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP + +       R        A  +L  Q   S G  +        RR SFLYRSDS   L+ K  +R  S  S +        V       +D++VTPFAQ+L +LR V++  A +  L+ +    +        +   +  ++T P +  +TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL Q  + SR+GN+ + ++I  TF+++        P   E+       +Q    SG      SP +         +S   E +L +       WG DIF+++  +    L  I  SI + R +  + K+   T I F+  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +AL  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + SK Q+Q +R+MVIDMVLATDMSKHM  LADLKTMVETKKV+  G+L LDNY+DRIQ+LQN++HCADLSNPTKP+ +Y QWT+R+M E+F+QGD+E++ G+E SPMCD+ TASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   55 LKKPRMSWPSSFHK------RFDVENGLSAGRALDPQVSPSSGLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQ-VSEFIASTFLEKQHDVEILSPPPKEKEKKRRPMSQI---SGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVEDINRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 639
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 484.952 bits (1247), Expect = 2.257e-162
Identity = 262/582 (45.02%), Postives = 366/582 (62.89%), Query Frame = 3 
Query:  285 QKNIRETCRGSAGAAESLKDQKFTSHGEFIS-------RRNSFLYRSDS---LNSKYFTRGISAKSSV------CHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEI---NFSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQ--KNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWK----------SGENFNLESPKVEKEIHNMCQIS---EMILCE-------WGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            QK  R        A  +L  Q   S G  +        RR SFLYRSDS   L+ K  +R  S  S +        V       +D++VTPFAQ+L +LR V++  A +  L+ +    +        +   +  ++T P +  +TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL Q  + SR+GN+ + ++I  TF+++      +H  E+L      K          SG      SP +         +S   E +L +       WG DIF+++  +    L  I  SI + R +  + K+   T I F+  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +AL  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + SK Q+Q +R+MVIDMVLATDMSKHM  LADLKTMVETKKV+  G+L LDNY+DRIQ+LQN++HCADLSNPTKP+ +Y QWT+R+M E+F+QGD+E++ G+E SPMCD+ TASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   39 QKRRRFDVENGLSAGRALDPQVSPSSGLVLQATFPHSQRRESFLYRSDSDFDLSPKAMSRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQ-VSEFIASTFLEK------QHDVEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVEDINRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 613
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 483.797 bits (1244), Expect = 3.740e-162
Identity = 254/544 (46.69%), Postives = 356/544 (65.44%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSV------CHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEI---NFSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQ--KNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWK----------SGENFNLESPKVEKEIHNMCQIS---EMILCE-------WGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S +        V       +D++VTPFAQ+L +LR V++  A +  L+ +    +        +   +  ++T P +  +TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL Q  + SR+GN+ + ++I  TF+++      +H  E+L      K          SG      SP +         +S   E +L +       WG DIF+++  +    L  I  SI + R +  + K+   T I F+  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +AL  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + SK Q+Q +R+MVIDMVLATDMSKHM  LADLKTMVETKKV+  G+L LDNY+DRIQ+LQN++HCADLSNPTKP+ +Y QWT+R+M E+F+QGD+E++ G+E SPMCD+ TASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   61 RRESFLYRSDSDFDLSPKAMSRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQ-VSEFIASTFLEK------QHDVEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVEDINRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 597
[Close]
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde4cb (phosphodiesterase 4C [Source:NCBI gene;Acc:103044346])

HSP 1 Score: 485.337 bits (1248), Expect = 4.723e-162
Identity = 254/544 (46.69%), Postives = 356/544 (65.44%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSV------CHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEI---NFSEETLPSVT-DTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQ--KNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWK----------SGENFNLESPKVEKEIHNMCQIS---EMILCE-------WGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S +        V       +D++VTPFAQ+L +LR V++  A +  L+ +    +        +   +  ++T P +  +TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL Q  + SR+GN+ + ++I  TF+++      +H  E+L      K          SG      SP +         +S   E +L +       WG DIF+++  +    L  I  SI + R +  + K+   T I F+  +E+ Y +  +YHN+IHAADVVQS HV++S  A + VF+DLEI +AL  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + SK Q+Q +R+MVIDMVLATDMSKHM  LADLKTMVETKKV+  G+L LDNY+DRIQ+LQN++HCADLSNPTKP+ +Y QWT+R+M E+F+QGD+E++ G+E SPMCD+ TASV KSQV FID+IV+PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:  112 RRESFLYRSDSDFDLSPKAMSRNSSTASELEEGLKQWEVSCLPRHGEDMIVTPFAQVLASLRTVRSNFAALTHLQDRGGCKRPTGSNPPSMCKPSLPDDTYPKLAIETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQ-VSEFIASTFLEK------QHDVEILSPPPKEKEKKRRPMSQISGVKKLTHSPSLAPTCIPRFGVSTEHESLLAKEVEDINRWGLDIFKIAEHSGNRPLTVIMYSIFQERDLLKSFKIPTDTFITFMMTLEDHYHADVAYHNNIHAADVVQSTHVLLSSPALEAVFTDLEIMAALFASAIHDVDHPGVSNQFLINTNSELALMYNDASVLENHHLAVGFKLLQEENCDIFQNLSKKQRQSLRKMVIDMVLATDMSKHMNFLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLEIYRQWTDRIMVEYFTQGDRERDRGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQ 648
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007435.1 (pep scaffold:Pmarinus_7.0:GL486982:1709:8825:-1 gene:ENSPMAG00000006710.1 transcript:ENSPMAT00000007435.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 296.975 bits (759), Expect = 2.321e-97
Identity = 134/199 (67.34%), Postives = 168/199 (84.42%), Query Frame = 3 
Query: 1233 VFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQ-VSFIDFIVYPLW 1826
            VF+DLEI +A+  + IHD+DHPGV+NQFLINTN  LA++YND SVLENHHLAVGF L++  +C+I  + SK Q+Q +R+MVIDMVLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY DRIQ+LQN++HCADLSNPTKP+ +Y QWTER+MEEFF QGD+E+E G+E SPMCD+ +ASV KSQ ++ IDF ++  W
Sbjct:    7 VFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEENCDIFQNLSKKQRQTLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLQNMVHCADLSNPTKPLDVYRQWTERIMEEFFRQGDRERERGMEISPMCDKHSASVEKSQRINAIDFSLHCWW 205
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007498.1 (pep scaffold:Pmarinus_7.0:GL486417:1684:4657:1 gene:ENSPMAG00000006774.1 transcript:ENSPMAT00000007498.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 230.72 bits (587), Expect = 1.470e-72
Identity = 102/140 (72.86%), Postives = 121/140 (86.43%), Query Frame = 3 
Query: 1485 VLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            VLATDMSKHM +L DLKT VETKKV+ SG+L LDNY DRIQ+LQN++HCADLSNPTKP+ LY QWTER+MEEFF QGD+E+E GI+ SPMCDR +ASV KSQV FID+IV+PLWETWA+LVQP+A  ML+ L ENR +Y+
Sbjct:    2 VLATDMSKHMNLLGDLKTTVETKKVTSSGVLLLDNYTDRIQVLQNMVHCADLSNPTKPLGLYRQWTERIMEEFFQQGDRERERGIDISPMCDRHSASVEKSQVGFIDYIVHPLWETWADLVQPDAQEMLDTLEENRDFYQ 141
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde4ba (phosphodiesterase 4B, cAMP-specific a [Source:ZFIN;Acc:ZDB-GENE-030131-9570])

HSP 1 Score: 234.958 bits (598), Expect = 2.908e-71
Identity = 134/378 (35.45%), Postives = 215/378 (56.88%), Query Frame = 3 
Query:  492 DIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPS-------VTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLES-------------------------PKVEKEIHNMCQISEMILC------------EWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMV 1487
            D++VTPFAQ+L +LR V+   + +  L+G  T S+      ++ ++     PS         +T+  L+WCL QLE VQTHRSVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TFMD+      +H  EV    +  K  +   L S                           V++ +H    +   ++             +WG +IF+++  +    L  +  +I + R++    ++   T + ++  +E+ +    +YHNS+HAADV QS HV+++  A   VF+DLEI +A+  + IHD+DHPGV+NQFLI+TN  LA++YND SVLENHHLAVGF L++ ++C+I  +  K Q+Q +R+MVIDMV
Sbjct:    4 DLIVTPFAQVLASLRSVRNNFSALTNLQG--TPSR-RSPAGNQTSYPRAA-PSDEGYQKLALETMEELDWCLDQLEAVQTHRSVSEMASNKFKRMLNRELSHLSEMSRSGNQ-VSEFISSTFMDK------QHEMEVPSAGHKEKERQRRPLASGGGVAAVGGAAPAVPSQLAAGVSHISGVQRLLHGAAILQRAMIFRDALSQELEDINKWGINIFRIAELSNNRPLTVLMYTIFQERELLKTFQIPADTFVTYMMTLEDHHAGV-AYHNSLHAADVAQSTHVLLASPALDAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLGKKQRQTLRKMVIDMV 369
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde1a (phosphodiesterase 1A, calmodulin-dependent [Source:ZFIN;Acc:ZDB-GENE-090831-2])

HSP 1 Score: 222.246 bits (565), Expect = 7.272e-65
Identity = 107/280 (38.21%), Postives = 172/280 (61.43%), Query Frame = 3 
Query:  984 EWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSY-RSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYP 1820
            +W  D+F L+  +    L+ +   +L   ++ S  K+ ++ +++F+EA+E  Y +  N YHN  HAADV Q+VH ++      +  S+LE  + +  A IHD++H G TN F I T   +A+LYND +VLENHH++  + LM+++D NI  + SK   + +R +V++MVLATDMS H   +  +K+ ++  +             D+ + +  L+H  D+S+PTK   L+ +WTE +MEEFF QGD+E +LG+  SP+CDR +  VA+SQ+ F+DFIV P
Sbjct:  152 KWSFDVFVLNEASGEHALKFVMHELLTRYELISRYKIPVAALVSFVEALEAGYSKHKNPYHNLAHAADVTQTVHYLLLQSGLMHWLSELETLAVIFAAAIHDLEHTGTTNNFHIQTRSDVALLYNDRAVLENHHVSAAYRLMQDDDMNIFINLSKDDWRELRALVVEMVLATDMSCHFQQIKTMKSALQQPESI-----------DKSKAMSLLLHAGDISHPTKEWPLHQRWTEALMEEFFRQGDREAKLGLPFSPLCDRNSTMVAQSQIGFMDFIVEP 420
[Close]
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE1C (phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:8776])

HSP 1 Score: 213.001 bits (541), Expect = 3.168e-62
Identity = 111/289 (38.41%), Postives = 173/289 (59.86%), Query Frame = 3 
Query:  984 EWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSY-RSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMK-NNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAEL 1844
            +W  D+F L   +    L+ I   +     + +  K+ +S++++F+EA+E  Y +  N YHNS+HAADV Q+VH ++      +  ++LEI S +  A IHD +H G TN F I T    AILYND SVLENHH++  + LM+ + + NIL + SK   + +R +V++ VLATDMS H   L  +K +++  +    G+       ++ + +  ++H AD+S+P K  +L+ +WT  +MEEFF QGDKE ELG+  SP+CDR    V +SQ+ FID+IV P +    +L
Sbjct:  143 KWSFDVFALHEASGEHALKFIVYELFTRYDLIARFKIPVSSVVSFVEALEAGYSKHKNPYHNSVHAADVTQTVHYLMLKTGTIHWLNELEILSMIFAAAIHDYEHTGTTNNFHIQTRSDSAILYNDRSVLENHHVSAAYRLMQEDEEMNILINLSKDDWRELRALVVETVLATDMSCHFHQLKSIKNLLQQPE----GV-------EKPKAMSLMLHTADISHPAKNWNLHRRWTMSLMEEFFRQGDKEAELGLSFSPLCDRNATMVPQSQIGFIDYIVEPTFTVLTDL 420
[Close]
BLAST of Phosphodiesterase vs. Ensembl Yeast
Match: PDE2 (High-affinity cyclic AMP phosphodiesterase; component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon [Source:SGD;Acc:S000005887])

HSP 1 Score: 71.2478 bits (173), Expect = 1.793e-13
Identity = 56/193 (29.02%), Postives = 93/193 (48.19%), Query Frame = 3 
Query: 1125 AVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEF 1703
             +E+SY   N +HN  HA DV+Q+   + + +   N    L +  A +G   HD+ HPG  NQ L N    +A  + ++S+LEN H  +   L+  +   +L S SK +   I     + +LATDM+ H        +  E +       L  +N   +I ++  +I  AD+SN T+ +S+  +W   +  EF
Sbjct:  253 TLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDNPVQTLLLCMAAIG---HDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLL-SISKKKFDFIS----EAILATDMALH--------SQYEDR-------LMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEF 422
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO46133 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM4])

HSP 1 Score: 428.713 bits (1101), Expect = 1.305e-143
Identity = 233/529 (44.05%), Postives = 339/529 (64.08%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMDEVPYI----SEEHLDEVLFNQYNWKSG-------ENFNLESPKVEKEIHNMCQISEMI--LCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVS--GSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKEL-GIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYY 1901
            RR SFLY+SDS   L  K  T    + S    V++        +VTPFAQIL +LR V+     +   K K    K       + + S  +  +   TL  L+W LYQLE +QTH SVSE+A++KFKRLL++EL    + +++GN+ +  ++  TF D+   +    S+   D +     +  +G        +F+   P+   E+ N  +++ ++  + +W  D F L     G  +  ++ +IL+ R +    K+  +T IN++  VEN Y     +HN IHAADV Q+ HV++S  AF NVF+DLEI SA++ + +HD+DHPGV N FL+ TN  +A++YND SVLENHHLAV F L+++ DC+I  + SK ++Q  RRM+I+MVLATD +KHM++LA LKTMVETKKV+  GSG+L L+NY DR+Q+L++L+HCADLSNPTKP+ +Y +W +R+MEEFF QGDKE+++ G+E SPM DR  AS+ KSQV FIDF+  PLWETW ELVQP+A  +L+ + +NR++Y
Sbjct:    2 RRESFLYKSDSEFELAPKCVTSRHHSFSEGTRVEE--------LVTPFAQILSSLRNVRNTFVTLTNAK-KDKQFKHSCFCTSKCSHSFYSWVA-NSTLDELDWVLYQLETLQTHTSVSEMASNKFKRLLNRELKDFSEANQSGNQ-VSAWVYNTFTDKQLEVETAQSKTKRDCIRARSRSMVNGVRKLTRLHSFSGSVPRFGVEVQNESELATILENVNKWDFDAFALGEATNGHPMLAVSYTILQARDLLKIFKIKPTTFINYMTLVENHYLKDVPFHNCIHAADVTQTAHVLLSAQAFDNVFTDLEILSAIIASAVHDVDHPGVNNHFLVATNSEMALMYNDESVLENHHLAVAFQLLQHEDCDIFENLSKQERQTARRMIIEMVLATDNAKHMSLLASLKTMVETKKVAGTGSGVLCLENYTDRMQVLKSLVHCADLSNPTKPLPIYRKWVDRLMEEFFRQGDKERDIDGMEISPMMDRHNASIEKSQVVFIDFVAQPLWETWGELVQPDAQDLLDTIEDNRQWY 519
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO37301 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGA1])

HSP 1 Score: 258.07 bits (658), Expect = 4.841e-80
Identity = 131/290 (45.17%), Postives = 182/290 (62.76%), Query Frame = 3 
Query:  984 EWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSY-RSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQ 1850
            EW  D+F LS   EG  LR I   +L  R M  N K+   T+  FL+ VE  Y R +N YHN  HAADV  +VH  +  M      SDLE+F  LL A+IHD++H G TN F IN+   LA+LYND SVLENHH++  F ++++++ NIL+  +  Q   +R ++ID VLATDMS H   L  +K  +    V+GS I N        +++Q L+H AD+SNPTK  +++ QWT ++MEEFF+QGD E ELG++ SP+CDR T  + +SQ+ FIDFIV P  E  +E+++
Sbjct:   80 EWTFDVFALSESCEGHPLRYIGYEVLHRRDMLRNFKIHAMTLDRFLQDVETGYKRHSNPYHNDCHAADVTHTVHYFLECMGVSKYLSDLEVFGLLLSAIIHDLEHTGTTNAFHINSRSDLALLYNDRSVLENHHVSCAFRILQDDEKNILSGLNLEQYADVRSLMIDTVLATDMSSHFEQLRLMKVAL----VAGSPIENR-------EVVQLLLHVADISNPTKDWTIHRQWTTKIMEEFFTQGDMEIELGLDVSPLCDRSTTLIPESQIGFIDFIVSPALEVCSEVLE 358
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32142 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVX8])

HSP 1 Score: 209.149 bits (531), Expect = 1.222e-57
Identity = 120/359 (33.43%), Postives = 197/359 (54.87%), Query Frame = 3 
Query:  861 HLDEVLFNQYNWKSGENFNLES-PKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNND-CNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILN------LDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENS-PMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQ-PEANVMLNNLFENRKYYEK 1907
            H+ ++   + +  SG    +   P++  E+ N   + E    +W  DI +L   +    L  + + IL   ++   L +    + N+L+ +E +Y   N+YHNS HAADV+ +  V ++    K V   L+  ++L+ A++HD+DHPG TN FL N    LAILYNDI+VLE+HH A+ F L   +D  NI ++    + + +R+ +IDMV+AT+M++H   L+     +  ++ S +   N      L+   +R  I + LI CAD++NP +P  L  +W  R+ EE+FSQ D+EK  G+    P+ DR T +V +SQV FID+ V  L++ W      PE    + +L +N  Y++K
Sbjct:  484 HIYDIWIKEPSQGSGRAVPIGHLPEIPAEVSN-AMVDE---ADWDFDILKLEKASNHRPLYFLGLKILNRFRVCEKLNISEDYVKNWLQLIEANYHRKNAYHNSTHAADVLHATAVFLAKERVKAVLEPLDEVASLIAAIVHDVDHPGYTNSFLCNAGSELAILYNDIAVLESHHAALAFKLTARDDKSNIFSNLDVEEFRTVRQAIIDMVMATEMTRHFEHLSKFVNSINKRRSSSTPDSNTSTSTALNTPENRTLIKRMLIKCADIANPARPRYLCKEWAYRIAEEYFSQTDEEKRRGLPVVMPVFDRATCNVPRSQVWFIDYFVSDLYDAWDAFAYVPET---IRHLTDNYDYWKK 835
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO43748 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXZ4])

HSP 1 Score: 176.792 bits (447), Expect = 1.879e-49
Identity = 113/356 (31.74%), Postives = 169/356 (47.47%), Query Frame = 3 
Query:  918 LESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMM------------------------------------------------AFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSL-MKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWA 1838
             E P+ E+    M ++++     W   IF       G IL  ++  I +N   F   K+     +N+  A+E+ Y S   YHNSIHA+DV+Q V+ + +                                                  A  +V   LE+ S    A +HD DHPG TN FL+ T    A+LYND SVLENHH A  F+L M +   N L   S ++ +  R + I+ +LATD+ +H  +L+D          +  G +N D+  DR+  LQ  I  +D+S P+K   ++  WTER++EEF+ QGD E+  G+  SP  DR    VA+ Q SFI+ +V PL+ ++A
Sbjct:    8 FELPRSEELTRLMDKVTD-----WNFPIFDAC--EHGNILVQVSYRIFQNAGFFEIFKIPERKFLNYFFALESGYHSI-PYHNSIHASDVLQGVYFLTTAKIPGFCPPGTPQKLGDNESDSDSDSGITSGVLGEGEEDKKDDDGGGDYGALVDVIPLLELLSLYTAAAMHDYDHPGRTNAFLVATLSHQALLYNDRSVLENHHAAAAFTLLMSDPKYNFLCELSPAEFKRFRFLAIEAILATDLKRHFDILSDFNAK------TAEGGVNWDSEADRLLTLQFCIKMSDISGPSKRRDIHTLWTERIVEEFYEQGDDERARGMAVSPYMDRQQPHVAQLQDSFINHLVAPLYNSYA 349
[Close]
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVS5])

HSP 1 Score: 156.377 bits (394), Expect = 4.929e-41
Identity = 85/257 (33.07%), Postives = 138/257 (53.70%), Query Frame = 3 
Query: 1074 MFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAEL 1844
            +    K++ S + +FL  V   Y  T  +HN  HA  V Q ++ +I +    N  +  ++   L  A+ HD+DHPG  N + IN    LA+ YNDIS LENHH AV F +MK +  NIL + S    + IR  +I  +L+TDM++H  +L   K ++++           D+   +  ++Q +I  +D+SN  +P+ +   W + +++EFF Q D EK  G+  +P  DR   +   +Q+ FI F++ PL+E   EL
Sbjct:  197 LLDEFKIERSKLQHFLFEVYRHYNPT-PFHNFRHAFCVTQMMYGLIWLTEIFNKITKQDLLIMLTSALCHDLDHPGYNNAYQINARTELALRYNDISPLENHHCAVAFDIMKQDKSNILQNVSAETFKKIREGMIKCILSTDMARHSDILNKFKELLKSG-------FKFDDEAHKSMLMQIMIKVSDVSNEARPMDVAEPWLDCLLQEFFIQSDVEKLEGLPVAPFMDRDKVTKPSAQIGFIKFVLVPLFEALGEL 445
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 485.337 bits (1248), Expect = 2.282e-161
Identity = 259/588 (44.05%), Postives = 373/588 (63.44%), Query Frame = 3 
Query:  237 LKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFIS-------RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDD----EINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            LK+ R SWP +  G  + ++     G++     L        G  +        RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+     +  ++ +   +K   + +     +  F+EE    + T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P    +   E      +  SG           N N+    V+ E  +        + +WG ++F+++  +    L  +  +I + R +    K+ + T I +L  +E+ Y    +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLI+TN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+  ASV KSQV FID+I +PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   84 LKKSRMSWPSSFQGLRRFDVDN---GTSSGRSPLDPMASPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISSTFLDKQHEVEMPTPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQ 659
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4ca (cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Source:NCBI gene;Acc:101161266])

HSP 1 Score: 481.1 bits (1237), Expect = 5.806e-161
Identity = 263/584 (45.03%), Postives = 374/584 (64.04%), Query Frame = 3 
Query:  267 TSNGKNQKNIRETCRG-----SAGAAESLKDQKFTSHGEFIS-------RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTD------TLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQ--KNSRNGNKNICDYICQTFMDEV-------PYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCE-------WGPDIFQLSTKNEGCILRNITM-SILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            T  GK Q   R  C       SAG    +  Q     G  +        RR SFLYRSDS   L+ K  TR  S+ S +         S+D++VTPFAQ+L +LR V+   + +   + + T SK+    ++  + S+ +L    D      TL  L+WCL QLE ++T  SVSE+A++KFKR+L++EL Q  + SR+GN+ + ++I  TF+++        P   E+   +   +Q +      ++L    + +   N  Q  E +L +       WG DIF+++ +  G     +TM SI + R +    K+ +   INF+  +E+ Y S  +YHN+IHAADVVQS+HV++S  A + VF+DLEI +AL  + IHD+DHPGV+NQFLINTN  LA++YND+SVLENHHLAVGF L++ + C+I    SK Q+Q +R+MVIDMVLATDMSKHM +LADLKTMVETKKV+  G+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY +WT+R+M EFF+QGD+E++ G+E SPMCD+  AS+ K+QV FID+I +PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   36 TKRGKRQDPERRGCFDVENGLSAGRGGPIDAQVNPGSGLVLQANFPHSQRRESFLYRSDSDFDLSPKGPTRNPSSASDL--------HSEDMIVTPFAQVLASLRTVRNNFSTITGQQDR-TVSKMRS-SNNPPSVSKTSLAEEPDQQLAIETLDELDWCLEQLETLKTRHSVSEMASNKFKRMLNRELTQLSETSRSGNQ-VSEFISSTFLEKSHDMDIMSPPSKEKDKRKRPMSQISGVRKPTYSLAPSSIPRFGVNASQ--EGLLAKQLEDINRWGIDIFKVA-EYSGTRPLTVTMYSIFQERDLLKTFKIPVDIFINFVMTLEDHYHSEVAYHNNIHAADVVQSMHVLLSTPALEAVFTDLEILAALFASAIHDVDHPGVSNQFLINTNSELALMYNDMSVLENHHLAVGFKLLQEDQCDIFQDLSKKQRQSLRKMVIDMVLATDMSKHMNLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLELYRKWTDRIMVEFFTQGDRERDKGMEISPMCDKHNASIEKNQVGFIDYIAHPLWETWADLVHPDAQEILDTLEDNREWYQ 605
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 480.33 bits (1235), Expect = 1.165e-160
Identity = 249/534 (46.63%), Postives = 355/534 (66.48%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDD----EINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+     +  ++ +   +K   + +     +  F+EE    + T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P    +   E      +  SG           N N+    V+ E  +        + +WG ++F+++  +    L  +  +I + R +    K+ + T I +L  +E+ Y    +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLI+TN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+  ASV KSQV FID+I +PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   62 RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISSTFLDKQHEVEMPTPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQ 586
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 479.174 bits (1232), Expect = 3.474e-160
Identity = 249/534 (46.63%), Postives = 355/534 (66.48%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDD----EINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+     +  ++ +   +K   + +     +  F+EE    + T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P    +   E      +  SG           N N+    V+ E  +        + +WG ++F+++  +    L  +  +I + R +    K+ + T I +L  +E+ Y    +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLI+TN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+  ASV KSQV FID+I +PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:   65 RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISSTFLDKQHEVEMPTPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQ 589
[Close]
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde4d (phosphodiesterase 4D [Source:NCBI gene;Acc:101167796])

HSP 1 Score: 481.1 bits (1237), Expect = 8.509e-160
Identity = 249/534 (46.63%), Postives = 355/534 (66.48%), Query Frame = 3 
Query:  378 RRNSFLYRSDS---LNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDD----EINFSEETLPSV-TDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKEL--IQKNSRNGNKNICDYICQTFMD-----EVPYISEEHLDEVLFNQYNWKSG----------ENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYYE 1904
            RR SFLYRSDS   L+ K  +R  S  S + H D       D++VTPFAQ+L +LR V+     +  ++ +   +K   + +     +  F+EE    + T+TL  L+WCL QLE +QT  SVSE+A++KFKR+L++EL  + + SR+GN+ + ++I  TF+D     E+P    +   E      +  SG           N N+    V+ E  +        + +WG ++F+++  +    L  +  +I + R +    K+ + T I +L  +E+ Y    +YHN+IHAADV QS HV++S  A + VF+DLEI +A+  + IHD+DHPGV+NQFLI+TN  LA++YND SVLENHHLAVGF L++  +C+I  + +K Q+Q +R+MVID+VLATDMSKHM +LADLKTMVETKKV+ SG+L LDNY+DRIQ+LQN++HCADLSNPTKP+ LY QWT+R+MEEFFSQGD+E+E G+E SPMCD+  ASV KSQV FID+I +PLWETWA+LV P+A  +L+ L +NR++Y+
Sbjct:  127 RRESFLYRSDSDYDLSPKSMSRNSSIASDI-HGD-------DMIVTPFAQVLASLRTVRNNFGALTNVQQERASTKRSPMCNPPPITKTTFTEEAYQKLATETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQ-VSEFISSTFLDKQHEVEMPTPQTQKEKEKKNKPMSQISGVKKLQHSSSLTNSNIPRFGVKTETEDELAKELEHVNKWGLNVFKITEFSGNRPLTVMMHTIFQERDLLKTFKIPLDTFITYLLTLEDHYHGDVAYHNNIHAADVTQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLISTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFSQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIAHPLWETWADLVHPDAQDILDTLEDNREWYQ 651
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000034048.1 (SMESG000034048.1)

HSP 1 Score: 974.156 bits (2517), Expect = 0.000e+0
Identity = 470/478 (98.33%), Postives = 472/478 (98.74%), Query Frame = 3 
Query:   75 MEHFKMNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSK 1508
            MEHFKMNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITM ILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDM     ++K
Sbjct:    1 MEHFKMNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMPILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMAFVERLTK 478
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000034048.1 (SMESG000034048.1)

HSP 1 Score: 971.844 bits (2511), Expect = 0.000e+0
Identity = 469/470 (99.79%), Postives = 469/470 (99.79%), Query Frame = 3 
Query:   75 MEHFKMNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDM 1484
            MEHFKMNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITM ILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDM
Sbjct:    1 MEHFKMNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMPILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDM 470
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000034048.1 (SMESG000034048.1)

HSP 1 Score: 962.985 bits (2488), Expect = 0.000e+0
Identity = 465/473 (98.31%), Postives = 467/473 (98.73%), Query Frame = 3 
Query:   90 MNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSK 1508
            MNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITM ILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDM     ++K
Sbjct:    1 MNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMPILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMAFVERLTK 473
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000034048.1 (SMESG000034048.1)

HSP 1 Score: 961.059 bits (2483), Expect = 0.000e+0
Identity = 464/465 (99.78%), Postives = 464/465 (99.78%), Query Frame = 3 
Query:   90 MNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDM 1484
            MNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITM ILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDM
Sbjct:    1 MNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKRKPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFISRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQTFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEMILCEWGPDIFQLSTKNEGCILRNITMPILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDM 465
[Close]
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000032148.1 (SMESG000032148.1)

HSP 1 Score: 488.034 bits (1255), Expect = 3.099e-165
Identity = 267/572 (46.68%), Postives = 358/572 (62.59%), Query Frame = 3 
Query:  378 RRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQILLTLRMVK-----------TKLAQMFQLKGKSTDSKLED--IEDDEINFSEETLPSVTDTLSNLEWCLYQLENVQTHRSVSELATSKFKRLLSKELIQ--KNSRNGNKNICDYICQTFMD----------------EVPY--ISEEHLDEVLFNQYNWKSGENFNLESPKV----EKEIHN---------------------------MCQISEMILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLEAVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGAVIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCNILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGILNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKEKELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLNNLFENRKYY 1901
            RR SFLYR    +     R     S           S D++VTPFAQIL +LR V+           ++ A+   +   S   + ED  IE D+   S+ +L    +TL  LEWCL +LE++QTHRSVS++A+SKFK++L+KEL Q    S++GN+ I DYIC TF+D                + P    S E LDE           E +   +P +     ++IH                            M +I E  L  WG DIF +ST ++   L  I+ ++    K+F    +  S  ++F+  +EN Y     YHNS HAADV QS +V++  ++ +NVFSDLEI + +   +IHD+DHPGVTNQ+LINTND LA++YND SVLENHHL+V F+++   +C+I+T+ +K Q+Q  R+MVIDMVLATDMSKHM++LADLKTMVETKKV+GSGILNLDNYNDRIQILQN++HCADLSNPTKP++LY  WTE++M+EFF QGDKE+E  +E SPMCDR TA+V KSQVSFIDFIV+PLWETW++LV PEA  +L+ L +NR++Y
Sbjct:   36 RRESFLYRGIDTDFSPSPRSSRHASIAFGEPHAFAHSDDLIVTPFAQILASLRNVRANFILITNVQSSREARFGSISASSHTLRSEDLKIEGDD---SQRSL--TMETLEELEWCLERLESMQTHRSVSDMASSKFKKILNKELSQYADQSKSGNQ-ISDYICTTFLDADGDNSLDQTSEYEDTDPPRRGSSREELDE----HSETDESERYADGAPSLISNEHQKIHKQTISFKPIFVDIENVSTFGINSTRNVEMTEIIETTLDTWGMDIFLVSTLSDNNPLTVISFALFRKYKLFEKFSIQSSIFLSFITEIENKYHKDVPYHNSTHAADVTQSTNVLLGALSLENVFSDLEIMAVIFACIIHDVDHPGVTNQYLINTNDQLALMYNDASVLENHHLSVAFTVLSLPNCDIITNLTKKQRQSFRKMVIDMVLATDMSKHMSLLADLKTMVETKKVAGSGILNLDNYNDRIQILQNMVHCADLSNPTKPLNLYRSWTEKIMQEFFRQGDKEREKNLEISPMCDRETATVEKSQVSFIDFIVHPLWETWSDLVYPEAQDILDTLEKNREWY 597
The following BLAST results are available for this feature:
BLAST of Phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PDE4D5.034e-16344.73phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:... [more]
PDE4D7.150e-16347.18phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:... [more]
PDE4D1.928e-16247.18phosphodiesterase 4D [Source:HGNC Symbol;Acc:HGNC:... [more]
AC008397.22.035e-16244.07cAMP-specific 3',5'-cyclic phosphodiesterase 4C [... [more]
PDE4C2.035e-16244.07phosphodiesterase 4C [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of Phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde-45.621e-15642.74Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-41.122e-15542.74Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-41.633e-15542.74Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-46.205e-15542.74Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
pde-41.464e-15443.49Probable 3',5'-cyclic phosphodiesterase pde-4 [So... [more]
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BLAST of Phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnc1.369e-15644.68gene:FBgn0000479 transcript:FBtr0333317[more]
dnc1.369e-15644.68gene:FBgn0000479 transcript:FBtr0333316[more]
dnc1.934e-15644.94gene:FBgn0000479 transcript:FBtr0070520[more]
dnc3.454e-15644.68gene:FBgn0000479 transcript:FBtr0070517[more]
dnc3.708e-15644.68gene:FBgn0000479 transcript:FBtr0333314[more]
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BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde4d6.213e-16447.38phosphodiesterase 4D, cAMP-specific [Source:ZFIN;A... [more]
pde4d1.089e-16347.38phosphodiesterase 4D, cAMP-specific [Source:ZFIN;A... [more]
BX510928.21.186e-16347.64phosphodiesterase 4D, cAMP-specific [Source:NCBI g... [more]
pde4ca1.104e-16143.11phosphodiesterase 4C, cAMP-specific a [Source:ZFIN... [more]
pde4ca1.104e-16143.11phosphodiesterase 4C, cAMP-specific a [Source:ZFIN... [more]
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BLAST of Phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plxnb11.793e-16348.80plexin B1 [Source:Xenbase;Acc:XB-GENE-856606][more]
PDE4D2.154e-16345.03phosphodiesterase 4D [Source:NCBI gene;Acc:1004964... [more]
PDE4D3.722e-16347.48phosphodiesterase 4D [Source:NCBI gene;Acc:1004964... [more]
PDE4D6.552e-16347.48phosphodiesterase 4D [Source:NCBI gene;Acc:1004964... [more]
PDE4D1.194e-16247.48phosphodiesterase 4D [Source:NCBI gene;Acc:1004964... [more]
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BLAST of Phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pde4d4.514e-16344.90phosphodiesterase 4D, cAMP specific [Source:MGI Sy... [more]
Pde4c6.680e-16345.97phosphodiesterase 4C, cAMP specific [Source:MGI Sy... [more]
Pde4c6.680e-16345.97phosphodiesterase 4C, cAMP specific [Source:MGI Sy... [more]
Pde4d1.244e-16247.37phosphodiesterase 4D, cAMP specific [Source:MGI Sy... [more]
Pde4c1.312e-16245.97phosphodiesterase 4C, cAMP specific [Source:MGI Sy... [more]
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BLAST of Phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q08499|PDE4D_HUMAN2.417e-16244.73cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS... [more]
sp|Q3UEI1|PDE4C_MOUSE9.174e-16245.97cAMP-specific 3',5'-cyclic phosphodiesterase 4C OS... [more]
sp|Q08493|PDE4C_HUMAN9.771e-16244.07cAMP-specific 3',5'-cyclic phosphodiesterase 4C OS... [more]
sp|P14270|PDE4D_RAT1.173e-16144.73cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS... [more]
sp|Q01063|PDE4D_MOUSE4.271e-16147.37cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS... [more]
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BLAST of Phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4W6C4221.248e-16245.24Phosphodiesterase OS=Lates calcarifer OX=8187 GN=L... [more]
A0A3B3R0M01.315e-16244.90Phosphodiesterase OS=Paramormyrops kingsleyae OX=1... [more]
A0A3B3R0F01.529e-16245.36Phosphodiesterase OS=Paramormyrops kingsleyae OX=1... [more]
A0A1A8N8D91.682e-16245.24Phosphodiesterase (Fragment) OS=Nothobranchius rac... [more]
A0A1S3FY002.597e-16244.90Phosphodiesterase OS=Dipodomys ordii OX=10020 GN=P... [more]
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BLAST of Phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde4cb4.490e-16444.76phosphodiesterase 4C [Source:NCBI gene;Acc:1030443... [more]
pde4cb6.304e-16344.54phosphodiesterase 4C [Source:NCBI gene;Acc:1030443... [more]
pde4cb2.257e-16245.02phosphodiesterase 4C [Source:NCBI gene;Acc:1030443... [more]
pde4cb3.740e-16246.69phosphodiesterase 4C [Source:NCBI gene;Acc:1030443... [more]
pde4cb4.723e-16246.69phosphodiesterase 4C [Source:NCBI gene;Acc:1030443... [more]
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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000007435.12.321e-9767.34pep scaffold:Pmarinus_7.0:GL486982:1709:8825:-1 ge... [more]
ENSPMAT00000007498.11.470e-7272.86pep scaffold:Pmarinus_7.0:GL486417:1684:4657:1 gen... [more]
pde4ba2.908e-7135.45phosphodiesterase 4B, cAMP-specific a [Source:ZFIN... [more]
pde1a7.272e-6538.21phosphodiesterase 1A, calmodulin-dependent [Source... [more]
PDE1C3.168e-6238.41phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of Phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PDE21.793e-1329.02High-affinity cyclic AMP phosphodiesterase; compon... [more]
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BLAST of Phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO461331.305e-14344.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO373014.841e-8045.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO321421.222e-5733.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO437481.879e-4931.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO321794.929e-4133.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pde4d2.282e-16144.05phosphodiesterase 4D [Source:NCBI gene;Acc:1011677... [more]
pde4ca5.806e-16145.03cAMP-specific 3',5'-cyclic phosphodiesterase 4C [S... [more]
pde4d1.165e-16046.63phosphodiesterase 4D [Source:NCBI gene;Acc:1011677... [more]
pde4d3.474e-16046.63phosphodiesterase 4D [Source:NCBI gene;Acc:1011677... [more]
pde4d8.509e-16046.63phosphodiesterase 4D [Source:NCBI gene;Acc:1011677... [more]
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BLAST of Phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000034048.10.000e+098.33SMESG000034048.1[more]
SMESG000034048.10.000e+099.79SMESG000034048.1[more]
SMESG000034048.10.000e+098.31SMESG000034048.1[more]
SMESG000034048.10.000e+099.78SMESG000034048.1[more]
SMESG000032148.13.099e-16546.68SMESG000032148.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023210 ID=SMED30023210|Name=Phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=2045bp
TTCATACAATAGTTTGTATAGTTAGACAATGCTTTGCTAAAATAATTCCT
AACAAATGATTATTATCATGACAAATGGAGCATTTTAAAATGAACAGACA
AATCTATTCGTGTCCGGATTATAATCACAAAACAGATTTAATTGGAAAAC
CCATTAATTTATCAATCCATGAAAACGATTCAAATTGGATAAATAAAGTG
GTCAATATTCCGACATCAAAACGAAAGCCAATTATTCTCAAACGAGGTCG
AAGTTCTTGGCCAGTAACGAGCAATGGGAAAAATCAGAAAAATATTCGTG
AAACCTGTCGTGGATCTGCAGGTGCTGCTGAAAGTTTAAAAGATCAAAAA
TTTACAAGTCACGGGGAATTTATTTCTCGTCGAAATTCATTTCTTTATCG
ATCCGATTCGTTAAATTCCAAATATTTTACTCGGGGAATTTCGGCAAAAT
CTTCGGTATGTCATGTGGACCAAACTCTAAACAAATCTCAAGACATTGTC
GTTACTCCATTTGCACAAATTCTGCTCACATTGAGAATGGTCAAAACAAA
ATTGGCTCAGATGTTCCAACTAAAAGGAAAATCAACAGATTCAAAACTAG
AAGACATAGAAGATGATGAAATTAATTTTTCCGAAGAGACCTTGCCATCG
GTAACAGATACCTTATCAAATCTTGAATGGTGCCTTTACCAACTTGAAAA
CGTCCAAACGCACAGATCGGTCAGTGAACTAGCTACTAGCAAGTTCAAAC
GGCTACTCAGTAAGGAATTGATTCAAAAAAATTCCAGAAATGGTAATAAA
AACATTTGCGACTACATTTGCCAAACATTTATGGACGAAGTTCCATATAT
TTCTGAAGAGCATTTAGATGAAGTTTTATTTAATCAATATAATTGGAAAT
CGGGAGAAAATTTTAACTTGGAAAGTCCCAAAGTGGAAAAAGAAATTCAT
AATATGTGTCAAATATCGGAAATGATTCTGTGTGAATGGGGGCCAGATAT
TTTCCAATTGTCAACCAAGAACGAAGGCTGTATTTTACGCAATATAACAA
TGTCAATACTAGAAAACAGAAAAATGTTCTCAAATCTTAAACTCGACATG
TCGACAATGATTAACTTCCTAGAAGCAGTAGAAAACAGTTACCGATCAAC
AAACAGTTATCATAATAGTATTCACGCTGCCGACGTAGTGCAATCCGTTC
ACGTTATTATATCAATGATGGCATTCAAGAATGTCTTTTCTGATTTGGAA
ATATTTTCTGCTCTTTTGGGTGCAGTCATTCATGACATCGATCATCCTGG
TGTTACTAATCAGTTTTTGATCAATACAAACGATTCTTTGGCCATTCTAT
ACAATGATATATCAGTATTAGAAAATCACCACTTAGCTGTTGGATTCTCT
CTAATGAAAAACAATGATTGTAATATTCTCACATCCTTTAGCAAATCTCA
GCAGCAAGTCATACGGAGAATGGTTATTGATATGGTGTTAGCAACGGACA
TGTCGAAGCATATGACAATGTTGGCCGATTTAAAAACAATGGTTGAAACA
AAAAAAGTATCCGGATCTGGAATTCTTAATTTAGATAACTATAATGATAG
GATTCAGATACTTCAAAATTTAATTCATTGTGCCGATTTGAGCAATCCTA
CAAAACCAATATCGCTTTATGTGCAATGGACGGAACGAGTTATGGAGGAG
TTTTTCAGTCAGGGAGATAAAGAGAAAGAACTCGGTATTGAAAATAGTCC
AATGTGTGACCGTTTAACAGCCTCAGTTGCCAAATCTCAAGTCAGTTTTA
TTGATTTTATTGTCTACCCTTTGTGGGAAACATGGGCAGAATTGGTTCAA
CCTGAAGCAAATGTGATGTTGAATAATTTATTTGAAAACCGCAAATACTA
TGAAAAAATTTCCATTGAAAATGAATCCAATATCAGTGAGTGATCAACTG
TGATTCTAAATTACGGAAATAAACTATTCAATGATCCACTGGTATTTTTG
TTTCACTTTTTATTTTATTGAAAAATACAGCACATTCAAAAAAAA
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protein sequence of SMED30023210-orf-1

>SMED30023210-orf-1 ID=SMED30023210-orf-1|Name=SMED30023210-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=623bp
MEHFKMNRQIYSCPDYNHKTDLIGKPINLSIHENDSNWINKVVNIPTSKR
KPIILKRGRSSWPVTSNGKNQKNIRETCRGSAGAAESLKDQKFTSHGEFI
SRRNSFLYRSDSLNSKYFTRGISAKSSVCHVDQTLNKSQDIVVTPFAQIL
LTLRMVKTKLAQMFQLKGKSTDSKLEDIEDDEINFSEETLPSVTDTLSNL
EWCLYQLENVQTHRSVSELATSKFKRLLSKELIQKNSRNGNKNICDYICQ
TFMDEVPYISEEHLDEVLFNQYNWKSGENFNLESPKVEKEIHNMCQISEM
ILCEWGPDIFQLSTKNEGCILRNITMSILENRKMFSNLKLDMSTMINFLE
AVENSYRSTNSYHNSIHAADVVQSVHVIISMMAFKNVFSDLEIFSALLGA
VIHDIDHPGVTNQFLINTNDSLAILYNDISVLENHHLAVGFSLMKNNDCN
ILTSFSKSQQQVIRRMVIDMVLATDMSKHMTMLADLKTMVETKKVSGSGI
LNLDNYNDRIQILQNLIHCADLSNPTKPISLYVQWTERVMEEFFSQGDKE
KELGIENSPMCDRLTASVAKSQVSFIDFIVYPLWETWAELVQPEANVMLN
NLFENRKYYEKISIENESNISE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036971PDEase_catalytic_dom_sf
IPR040844PDE4_UCR
IPR023088PDEase
IPR003607HD/PDEase_dom
IPR002073PDEase_catalytic_dom
IPR023174PDEase_CS
Vocabulary: molecular function
TermDefinition
GO:0008081phosphoric diester hydrolase activity
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity
GO:0016787hydrolase activity
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0007165signal transduction
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR0230883'5'-cyclic nucleotide phosphodiesterasePRINTSPR00387PDIESTERASE1coord: 358..371
score: 52.57
coord: 403..418
score: 58.5
coord: 430..446
score: 52.59
coord: 389..402
score: 38.14
coord: 517..530
score: 52.43
coord: 534..550
score: 59.06
IPR0369713'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamilyGENE3DG3DSA:1.10.1300.10coord: 295..622
e-value: 2.0E-128
score: 430.3
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainPFAMPF00233PDEase_Icoord: 362..602
e-value: 2.3E-87
score: 292.7
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainPROSITEPS51845PDEASE_I_2coord: 283..616
score: 120.306
IPR040844Phosphodiesterase 4 upstream conserved regions (UCR)PFAMPF18100PDE4_UCRcoord: 143..254
e-value: 4.5E-28
score: 98.3
NoneNo IPR availablePANTHERPTHR11347:SF74CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4Acoord: 101..255
coord: 302..611
NoneNo IPR availablePANTHERPTHR11347CYCLIC NUCLEOTIDE PHOSPHODIESTERASEcoord: 101..255
coord: 302..611
NoneNo IPR availableSUPERFAMILYSSF109604HD-domain/PDEase-likecoord: 299..613
IPR0231743'5'-cyclic nucleotide phosphodiesterase, conserved sitePROSITEPS00126PDEASE_I_1coord: 403..414
IPR003607HD/PDEase domainCDDcd00077HDccoord: 362..544
e-value: 6.82144E-14
score: 67.3645