Tau tubulin kinase

Overview


Name	Tau tubulin kinase
Smed ID	SMED30023193
Length (bp)	4469

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Tau tubulin kinase (SMED30023193) t-SNE clustered cells

Violin plots show distribution of expression levels for Tau tubulin kinase (SMED30023193) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tau tubulin kinase (SMED30023193) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tau tubulin kinase (SMED30023193) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30023193

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 15

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30023193	SMESG000026133.1	SmedASXL_016036	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30023193	SMESG000026133.1	dd_Smed_v4_12470_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30023193	SMESG000026133.1	dd_Smed_v4_12470_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30023193	SMESG000026133.1	dd_Smed_v4_12470_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30023193	SMESG000026133.1	dd_Smed_v4_12470_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30023193	SMESG000026133.1	dd_Smed_v4_12470_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30023193	SMESG000026133.1	Contig40606	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30023193	SMESG000026133.1	Contig40606	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
head region	SMED30023193	SMESG000026133.1	dd_Smed_v6_12470_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
reproductive organ	SMED30023193	SMESG000026133.1	Contig10388	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30023193	SMESG000026133.1	Contig10388	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
epidermis	SMED30023193	SMESG000026133.1	dd_Smed_v4_12470_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
ventral epidermis	SMED30023193	SMESG000026133.1	dd_Smed_v4_12470_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
dorsal region of the epidermis	SMED30023193	SMESG000026133.1	dd_Smed_v4_12470_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
ciliated epithelial cell	SMED30023193	SMESG000026133.1	dd_Smed_v4_12470_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Human
Match: TTBK2 (tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141])

HSP 1 Score: 340.502 bits (872), Expect = 1.909e-103
Identity = 184/300 (61.33%), Postives = 230/300 (76.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+F+ISTTL+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF    G   VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + +K+  V +SD FDWE
Sbjct:    1 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGD--VRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Human
Match: TTBK2 (tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141])

HSP 1 Score: 343.969 bits (881), Expect = 1.557e-97
Identity = 183/300 (61.00%), Postives = 230/300 (76.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+F+ISTTL+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF   +    VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + +K+  V +SD FDWE
Sbjct:    1 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Human
Match: TTBK1 (tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:19140])

HSP 1 Score: 339.732 bits (870), Expect = 1.105e-95
Identity = 177/300 (59.00%), Postives = 230/300 (76.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+     V+K+RWK++KK+GGGGFGEIYE +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRN+KF+YV M LQG+NLADLRR    G+F++STTL+L  QIL+SIE IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQ+   + +  VRPPR+VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVG IK  Y+H   L+ +P+EF  FL HI  LDYF KPDY+++ ++  + MK + + ++++FDWE
Sbjct:   14 MSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Human
Match: TTBK1 (tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:19140])

HSP 1 Score: 325.094 bits (832), Expect = 3.865e-95
Identity = 159/262 (60.69%), Postives = 201/262 (76.72%), Query Frame = 3

Query:  243 VDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRN+KF+YV M LQG+NLADLRR    G+F++STTL+L  QIL+SIE IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQ+    G   VRPPR+VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVG IK  Y+H   L+ +P+EF  FL HI  LDYF KPDY+++ ++  + MK + + ++++FDWE
Sbjct:    1 MDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGD--VRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 260

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Human
Match: TTBK2 (tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141])

HSP 1 Score: 288.115 bits (736), Expect = 2.684e-85
Identity = 162/300 (54.00%), Postives = 207/300 (69.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+F+ISTTL+L  QIL+SIE+IHS+GFLHRDIKP                                     PR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + +K+  V +SD FDWE
Sbjct:    1 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKP-------------------------------------PRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 263

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Celegans
Match: ttbk-7 (Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:Q22033])

HSP 1 Score: 307.375 bits (786), Expect = 8.589e-89
Identity = 172/333 (51.65%), Postives = 235/333 (70.57%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVK---DKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWEL---NXXXXXXXXXXXNIDTNMERRNSAII 1109
            MTSS+ E ++   G VI+ERWKI  K+GGGGFGEIYE  D  V+   ++VAIK+ESSK  KQVL+MEV+VL++LQG KHACK YG GRNDKF+Y+ M+LQGKNLADLRR+     F++ST +++ +QIL+ I  IHSIGFLHRD+KPSNFA+G +++T R VYMLDFGLARQ++   G  ++R PR  AGFRGTVRYA++ AH N EMGR DDLWS FYM  E + GQLPWR++KDK++VG++K   D    L   P+E   F+AH++ L Y   PDY  +++L+   +   +++  + +DWEL   N  +      + N+   ++   +A+I
Sbjct:    1 MTSSS-EGEILQVGQVIRERWKIKAKIGGGGFGEIYEATD--VQNHHERVAIKVESSKATKQVLKMEVAVLRRLQGKKHACKFYGCGRNDKFNYLVMSLQGKNLADLRREAPKQCFNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLNAKG--EIRSPRSAAGFRGTVRYAAVTAHKNKEMGRQDDLWSLFYMLTEFLQGQLPWRKIKDKDEVGKMKEEADLVVLLDDCPHEMHLFVAHLKVLGYADTPDYVYLESLLNKIVAENEISWDEPYDWELGYDNMATRQKQQANGNLSARLKSHTTAVI 328

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Celegans
Match: R13H9.5 (pep chromosome:WBcel235:IV:5065746:5066987:-1 gene:WBGene00020071.1 transcript:R13H9.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:R13H9.5)

HSP 1 Score: 186.422 bits (472), Expect = 4.858e-52
Identity = 125/311 (40.19%), Postives = 176/311 (56.59%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKL--QGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIG-GSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHT---KFLQSLP-NEFKPFLAHIQELDYFKKPD----YEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            MT+          G ++ ERW I KKLG GG G +Y C D     K A+K+E      QVL+MEV VL +L  +G++H CK    GR   F+YV MTL GK+L DLR+       S++ +L + +Q L+++E++H+IG+LHRD+KP N+ IG       R VY+LDFG+AR+F   D +  +R PR  AGFRGTVRYA +  H N E+GR DD+    YM  E+  G++PW+ + D   VGQ K    +T    F+   P NE K  +  +   DYF  P+    Y +MK  + +C K +       +DWE
Sbjct:    1 MTAPPPPLVELPPGSMV-ERWSITKKLGEGGCGAVYLCTD--ATGKYALKVEGISEAMQVLKMEVLVLGELTKRGSRHFCKIEDKGRYGSFNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYLHRDVKPGNYTIGRAELNELRKVYILDFGMARKFT--DNNGVIRKPRAAAGFRGTVRYAPIACHKNQELGRKDDVEVWLYMQVELTVGRVPWKEITDMNAVGQAKQTIRNTPEKMFVFPCPANELKEIMKMVDSWDYFADPNYADCYRLMKQALANCGKPEY-----PYDWE 301

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Celegans
Match: ttbk-2 (Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:O76712])

HSP 1 Score: 185.652 bits (470), Expect = 7.340e-52
Identity = 125/311 (40.19%), Postives = 176/311 (56.59%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKL--QGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIG-GSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHT---KFLQSLP-NEFKPFLAHIQELDYFKKPD----YEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            MT+          G ++ ERW I KKLG GG G +Y C D     K A+K+E      QVL+MEV VL +L  +G++H CK    GR   F+YV MTL GK+L DLR+       S++ +L + +Q L+++E++H+IG+LHRD+KP N+ IG       R VY+LDFG+AR+F   D +  +R PR  AGFRGTVRYA +  H N E+GR DD+    YM  E+  G++PW+ + D   VGQ K    +T    F+   P NE K  +  +   DYF  P+    Y +MK  + +C K +       +DWE
Sbjct:    1 MTAPPPPLVELPPGSMV-ERWSITKKLGEGGCGAVYLCTD--ATGKYALKVEGISEAMQVLKMEVLVLGELTKRGSRHFCKIEDKGRYGSFNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYLHRDVKPGNYTIGRAELNELRKVYILDFGMARKFT--DNNGVIRKPRAAAGFRGTVRYAPIACHKNQELGRKDDVEVWLYMQVELTVGRVPWKEITDMNAVGQAKQAIRNTPEKMFVFPCPANELKEIMKMVDSWDYFADPNYADCYRLMKQTLANCGKPEY-----PYDWE 301

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Celegans
Match: F35C11.3 (pep chromosome:WBcel235:II:8246776:8248263:1 gene:WBGene00009402.1 transcript:F35C11.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F35C11.3)

HSP 1 Score: 183.341 bits (464), Expect = 1.864e-50
Identity = 98/266 (36.84%), Postives = 160/266 (60.15%), Query Frame = 3

Query:  243 VDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPD--GSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDY-EMMKNLIRDCMKSKKVTQSDSFDWEL 1031
            V+P++K+K            ++L+MEV VLKKLQ ++H C+  G G+ + ++Y+ M++ GK + D+RR++     S  +T+++ +Q++ +++++H  GF+HRD+KPSN A+G   +  ++VY+ DFGL+RQ +LPD  G  ++R PR+ + FRGTVRY S+N H + E GRHDDL+ A Y   E  T  LPW+  K K++   +K      +  +  P  F      +++L Y + P Y   M+ L  D  K  K+T  D F+W L
Sbjct:   50 VEPLMKNK----------EDEILKMEVYVLKKLQNSRHVCRLLGSGKTETYTYMVMSVLGKEIGDVRRRLPQRKMSAPSTVRVFIQLVKALQDMHEAGFVHRDVKPSNMALG--VKNEQVVYIFDFGLSRQIMLPDASGKLKLREPRNKSMFRGTVRYCSLNVHLHKEQGRHDDLYGALYAMIETATSTLPWKG-KPKKETSALKEKTTDVQLCKGCPKSFLEIATTLRKLTYKETPPYGSFMEKLKADLPKGVKMT--DPFEWNL 300

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Celegans
Match: M05D6.1 (pep chromosome:WBcel235:II:8473819:8475406:-1 gene:WBGene00010874.1 transcript:M05D6.1.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:M05D6.1)

HSP 1 Score: 183.341 bits (464), Expect = 2.031e-50
Identity = 98/266 (36.84%), Postives = 160/266 (60.15%), Query Frame = 3

Query:  243 VDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPD--GSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDY-EMMKNLIRDCMKSKKVTQSDSFDWEL 1031
            V+P++K+K            ++L+MEV VLKKLQ ++H C+  G G+ + ++Y+ M++ GK + D+RR++     S  +T+++ +Q++ +++++H  GF+HRD+KPSN A+G   +  ++VY+ DFGL+RQ +LPD  G  ++R PR+ + FRGTVRY S+N H + E GRHDDL+ A Y   E  T  LPW+  K K++   +K      +  +  P  F      +++L Y + P Y   M+ L  D  K  K+T  D F+W L
Sbjct:   50 VEPLMKNK----------EDEILKMEVYVLKKLQNSRHVCRLLGSGKTETYTYMVMSVLGKEIGDVRRRLPQRKMSAPSTVRVFIQLVKALQDMHEAGFVHRDVKPSNMALG--VKNEQVVYIFDFGLSRQIMLPDASGKLKLREPRNKSMFRGTVRYCSLNVHLHKEQGRHDDLYGALYAMIETATSTLPWKG-KPKKETSALKEKTTDVQLCKGCPKSFLEIATTLRKLTYKETPPYGSFMEKLKADLPKGVKMT--DPFEWNL 300

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0300344)

HSP 1 Score: 338.191 bits (866), Expect = 4.985e-99
Identity = 181/292 (61.99%), Postives = 223/292 (76.37%), Query Frame = 3

Query:  153 DLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            DL   G V+KERWK+++K+GGGGFGEIYE  D I +++VA+K+ES++ PKQVL+MEV+VLKKLQG +H C+  G GRND+F+YV M LQGKNLA+LRR    G+FS+STTL+L LQIL +IE+IHS+GFLHRDIKPSNF++G      R VYMLDFGLARQ+    G+ +VR PR  AGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG  K  YDH   L+ LP++ K FL HIQ L Y  +PDY M+  L   CMK + V +SD +DWE
Sbjct:    5 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYT--TGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 294

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0344869)

HSP 1 Score: 338.576 bits (867), Expect = 9.565e-97
Identity = 181/292 (61.99%), Postives = 223/292 (76.37%), Query Frame = 3

Query:  153 DLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            DL   G V+KERWK+++K+GGGGFGEIYE  D I +++VA+K+ES++ PKQVL+MEV+VLKKLQG +H C+  G GRND+F+YV M LQGKNLA+LRR    G+FS+STTL+L LQIL +IE+IHS+GFLHRDIKPSNF++G      R VYMLDFGLARQ+    G+ +VR PR  AGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG  K  YDH   L+ LP++ K FL HIQ L Y  +PDY M+  L   CMK + V +SD +DWE
Sbjct:    5 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 294

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0332908)

HSP 1 Score: 338.576 bits (867), Expect = 9.565e-97
Identity = 181/292 (61.99%), Postives = 223/292 (76.37%), Query Frame = 3

Query:  153 DLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            DL   G V+KERWK+++K+GGGGFGEIYE  D I +++VA+K+ES++ PKQVL+MEV+VLKKLQG +H C+  G GRND+F+YV M LQGKNLA+LRR    G+FS+STTL+L LQIL +IE+IHS+GFLHRDIKPSNF++G      R VYMLDFGLARQ+    G+ +VR PR  AGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG  K  YDH   L+ LP++ K FL HIQ L Y  +PDY M+  L   CMK + V +SD +DWE
Sbjct:    5 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 294

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0332904)

HSP 1 Score: 338.191 bits (866), Expect = 2.062e-96
Identity = 181/292 (61.99%), Postives = 223/292 (76.37%), Query Frame = 3

Query:  153 DLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            DL   G V+KERWK+++K+GGGGFGEIYE  D I +++VA+K+ES++ PKQVL+MEV+VLKKLQG +H C+  G GRND+F+YV M LQGKNLA+LRR    G+FS+STTL+L LQIL +IE+IHS+GFLHRDIKPSNF++G      R VYMLDFGLARQ+    G+ +VR PR  AGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG  K  YDH   L+ LP++ K FL HIQ L Y  +PDY M+  L   CMK + V +SD +DWE
Sbjct:  161 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 450

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0332905)

HSP 1 Score: 338.576 bits (867), Expect = 2.922e-96
Identity = 181/292 (61.99%), Postives = 223/292 (76.37%), Query Frame = 3

Query:  153 DLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            DL   G V+KERWK+++K+GGGGFGEIYE  D I +++VA+K+ES++ PKQVL+MEV+VLKKLQG +H C+  G GRND+F+YV M LQGKNLA+LRR    G+FS+STTL+L LQIL +IE+IHS+GFLHRDIKPSNF++G      R VYMLDFGLARQ+    G+ +VR PR  AGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG  K  YDH   L+ LP++ K FL HIQ L Y  +PDY M+  L   CMK + V +SD +DWE
Sbjct:    5 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 294

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Zebrafish
Match: ttbk2a (tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-120928-3])

HSP 1 Score: 346.28 bits (887), Expect = 1.718e-99
Identity = 182/300 (60.67%), Postives = 232/300 (77.33%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+ S G ++KERWKI+KK+GGGGFGEIYE +D + +  VA+K ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR M  G+F++STTL+L LQIL++IE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF   +   +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG++K  YDH   L+ LP +F  FL HI  LDYF KPDY++++ +  + M++  V ++D +DWE
Sbjct:    1 MSGGLEQIDILSTGILVKERWKILKKIGGGGFGEIYEALDLMTRTSVALKAESAQQPKQVLKMEVAVLKKLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRSMNRGTFTVSTTLRLGLQILEAIESIHSVGFLHRDIKPSNFAMGRFPSTCRTCYMLDFGLARQFT--NSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKDKEQVGKLKETYDHRLMLKHLPPQFTVFLDHISNLDYFTKPDYQLLRTVFENSMRTYNVVENDPYDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Zebrafish
Match: ttbk2a (tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-120928-3])

HSP 1 Score: 347.051 bits (889), Expect = 5.060e-99
Identity = 182/300 (60.67%), Postives = 232/300 (77.33%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+ S G ++KERWKI+KK+GGGGFGEIYE +D + +  VA+K ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR M  G+F++STTL+L LQIL++IE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF   +   +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG++K  YDH   L+ LP +F  FL HI  LDYF KPDY++++ +  + M++  V ++D +DWE
Sbjct:    1 MSGGLEQIDILSTGILVKERWKILKKIGGGGFGEIYEALDLMTRTSVALKAESAQQPKQVLKMEVAVLKKLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRSMNRGTFTVSTTLRLGLQILEAIESIHSVGFLHRDIKPSNFAMGRFPSTCRTCYMLDFGLARQFT--NSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKDKEQVGKLKETYDHRLMLKHLPPQFTVFLDHISNLDYFTKPDYQLLRTVFENSMRTYNVVENDPYDWE 298

[Close]

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+ S G ++KERWKI+KK+GGGGFGEIYE +D + +  VA+K ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR M  G+F++STTL+L LQIL++IE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF   +   +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG++K  YDH   L+ LP +F  FL HI  LDYF KPDY++++ +  + M++  V ++D +DWE
Sbjct:    1 MSGGLEQIDILSTGILVKERWKILKKIGGGGFGEIYEALDLMTRTSVALKAESAQQPKQVLKMEVAVLKKLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRSMNRGTFTVSTTLRLGLQILEAIESIHSVGFLHRDIKPSNFAMGRFPSTCRTCYMLDFGLARQFT--NSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKDKEQVGKLKETYDHRLMLKHLPPQFTVFLDHISNLDYFTKPDYQLLRTVFENSMRTYNVVENDPYDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Zebrafish
Match: ttbk2b (tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-030131-8246])

HSP 1 Score: 341.273 bits (874), Expect = 6.937e-99
Identity = 177/300 (59.00%), Postives = 232/300 (77.33%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+ + ++ D+ + G +++ERW+++KK+GGGGFGEIYE +D + +  VA+K+ES++ PKQVL+MEV+VLK+LQG  H C+  G GRND+F+YV M LQG+NLADLRR M  G+FS+STTL+L  QIL++IE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF   +   +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG +K  Y+H   L+ LP+EF  F  HI  LDY+ KPDY+++ ++  + MKS  V ++D +DWE
Sbjct:    1 MSGTVEQTDILAVGSMVRERWRVLKKIGGGGFGEIYEVLDHVNQVSVALKVESAQQPKQVLKMEVAVLKRLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRNMSHGTFSVSTTLRLGRQILEAIESIHSVGFLHRDIKPSNFAMGRLNSTCRTCYMLDFGLARQFT--NSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKIKDKEQVGNMKETYNHRLLLKHLPDEFSVFFDHISNLDYYTKPDYQLLMSVFDNSMKSYNVVENDPYDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Zebrafish
Match: ttbk1a (tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-100609-4])

HSP 1 Score: 343.584 bits (880), Expect = 1.897e-97
Identity = 179/300 (59.67%), Postives = 231/300 (77.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M  + ++ D+     ++K+RWK++KK+GGGGFGEIYE +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H CK  G GRNDKF+YV M LQG+NLADLRR    G+F++STTL+L  QIL+SIE IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQ+   +G  +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVGQIK  YDH   L+ +P+EF  FL H+  LDY+ KPDY+++ ++  + MK + +T+++ +DWE
Sbjct:    1 MNGTAEQQDILPPHCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTFRKCYMLDFGLARQYTNTNG--EVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAAGQLPWRKIKDKEQVGQIKERYDHRMLLKHMPSEFNVFLEHVLALDYYTKPDYQLLMSVFENSMKERIITENEPYDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 343.969 bits (881), Expect = 8.874e-101
Identity = 185/300 (61.67%), Postives = 230/300 (76.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++PD+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+FSIST L+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF    G   VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  Y+H   L+ LP EF  FL HI  LDYF KPDY+++ ++  + MK+  V +SD FDWE
Sbjct:   12 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCG--DVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 309

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 345.51 bits (885), Expect = 3.723e-98
Identity = 184/300 (61.33%), Postives = 230/300 (76.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++PD+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+FSIST L+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF   +    VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  Y+H   L+ LP EF  FL HI  LDYF KPDY+++ ++  + MK+  V +SD FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 345.895 bits (886), Expect = 7.507e-98
Identity = 184/300 (61.33%), Postives = 230/300 (76.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++PD+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+FSIST L+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF   +    VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  Y+H   L+ LP EF  FL HI  LDYF KPDY+++ ++  + MK+  V +SD FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 328.176 bits (840), Expect = 2.892e-95
Identity = 166/265 (62.64%), Postives = 201/265 (75.85%), Query Frame = 3

Query:  234 YECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            Y+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+FSIST L+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF    G   VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  Y+H   L+ LP EF  FL HI  LDYF KPDY+++ ++  + MK+  V +SD FDWE
Sbjct:   33 YDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCG--DVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 295

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 290.041 bits (741), Expect = 7.024e-86
Identity = 163/300 (54.33%), Postives = 207/300 (69.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++PD+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+FSIST L+L  QIL+SIE+IHS+GFLHRDIKP                                     PR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  Y+H   L+ LP EF  FL HI  LDYF KPDY+++ ++  + MK+  V +SD FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKP-------------------------------------PRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 263

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Mouse
Match: Ttbk2 (tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:2155779])

HSP 1 Score: 346.28 bits (887), Expect = 3.340e-101
Identity = 183/300 (61.00%), Postives = 231/300 (77.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++PD+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+F+ISTTL+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  +MLDFGLARQF   +    VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + +K+  V +SD FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Mouse
Match: Ttbk1 (tau tubulin kinase 1 [Source:MGI Symbol;Acc:MGI:2147036])

HSP 1 Score: 337.421 bits (864), Expect = 4.915e-99
Identity = 178/300 (59.33%), Postives = 229/300 (76.33%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+     V+K+RWK++KK+GGGGFGEIYE +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRN+KF+YV M LQG+NLADLRR    G+F++STTL+L  QIL+SIE IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQ+    G   VRPPR+VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVG IK  Y+H   L+ +P+EF  FL HI  LDYF KPDY+++ ++  + MK + + ++++FDWE
Sbjct:   14 MSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGD--VRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Mouse
Match: Ttbk2 (tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:2155779])

HSP 1 Score: 347.436 bits (890), Expect = 8.830e-99
Identity = 183/300 (61.00%), Postives = 231/300 (77.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++PD+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+F+ISTTL+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  +MLDFGLARQF   +    VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + +K+  V +SD FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++PD+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+F+ISTTL+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  +MLDFGLARQF   +    VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + +K+  V +SD FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Mouse
Match: Ttbk2 (tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:2155779])

HSP 1 Score: 347.051 bits (889), Expect = 2.602e-98
Identity = 183/300 (61.00%), Postives = 231/300 (77.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++PD+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+F+ISTTL+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  +MLDFGLARQF   +    VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + +K+  V +SD FDWE
Sbjct:   70 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 367

[Close]

BLAST of Tau tubulin kinase vs. UniProt/SwissProt
Match: sp|Q3UVR3|TTBK2_MOUSE (Tau-tubulin kinase 2 OS=Mus musculus OX=10090 GN=Ttbk2 PE=1 SV=1)

HSP 1 Score: 347.436 bits (890), Expect = 6.177e-98
Identity = 183/300 (61.00%), Postives = 231/300 (77.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++PD+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+F+ISTTL+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  +MLDFGLARQF   +    VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + +K+  V +SD FDWE
Sbjct:    1 MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase vs. UniProt/SwissProt
Match: sp|Q6IQ55|TTBK2_HUMAN (Tau-tubulin kinase 2 OS=Homo sapiens OX=9606 GN=TTBK2 PE=1 SV=2)

HSP 1 Score: 343.969 bits (881), Expect = 7.478e-97
Identity = 183/300 (61.00%), Postives = 230/300 (76.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+ S G ++KERWK+++K+GGGGFGEIY+ +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR    G+F+ISTTL+L  QIL+SIE+IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQF   +    VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG IK  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + +K+  V +SD FDWE
Sbjct:    1 MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFT--NSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase vs. UniProt/SwissProt
Match: sp|Q6PCN3|TTBK1_MOUSE (Tau-tubulin kinase 1 OS=Mus musculus OX=10090 GN=Ttbk1 PE=1 SV=3)

HSP 1 Score: 339.732 bits (870), Expect = 4.677e-95
Identity = 177/300 (59.00%), Postives = 230/300 (76.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+     V+K+RWK++KK+GGGGFGEIYE +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRN+KF+YV M LQG+NLADLRR    G+F++STTL+L  QIL+SIE IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQ+   + +  VRPPR+VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVG IK  Y+H   L+ +P+EF  FL HI  LDYF KPDY+++ ++  + MK + + ++++FDWE
Sbjct:   14 MSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311

[Close]

BLAST of Tau tubulin kinase vs. UniProt/SwissProt
Match: sp|Q5TCY1|TTBK1_HUMAN (Tau-tubulin kinase 1 OS=Homo sapiens OX=9606 GN=TTBK1 PE=1 SV=2)

HSP 1 Score: 339.732 bits (870), Expect = 5.304e-95
Identity = 177/300 (59.00%), Postives = 230/300 (76.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   ++ D+     V+K+RWK++KK+GGGGFGEIYE +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRN+KF+YV M LQG+NLADLRR    G+F++STTL+L  QIL+SIE IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQ+   + +  VRPPR+VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVG IK  Y+H   L+ +P+EF  FL HI  LDYF KPDY+++ ++  + MK + + ++++FDWE
Sbjct:   14 MSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYT--NTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311

[Close]

BLAST of Tau tubulin kinase vs. UniProt/SwissProt
Match: sp|Q8IMC6|ASATR_DROME (Tau-tubulin kinase homolog Asator OS=Drosophila melanogaster OX=7227 GN=Asator PE=1 SV=2)

HSP 1 Score: 337.806 bits (865), Expect = 1.114e-94
Identity = 181/292 (61.99%), Postives = 223/292 (76.37%), Query Frame = 3

Query:  153 DLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            DL   G V+KERWK+++K+GGGGFGEIYE  D I +++VA+K+ES++ PKQVL+MEV+VLKKLQG +H C+  G GRND+F+YV M LQGKNLA+LRR    G+FS+STTL+L LQIL +IE+IHS+GFLHRDIKPSNF++G      R VYMLDFGLARQ+    G+ +VR PR  AGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG  K  YDH   L+ LP++ K FL HIQ L Y  +PDY M+  L   CMK + V +SD +DWE
Sbjct:  161 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTT--GTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWE 450

[Close]

BLAST of Tau tubulin kinase vs. TrEMBL
Match: A0A1A7WKG4 (Tau tubulin kinase 2 OS=Iconisemion striatum OX=60296 GN=TTBK2 PE=4 SV=1)

HSP 1 Score: 350.132 bits (897), Expect = 1.229e-104
Identity = 184/300 (61.33%), Postives = 234/300 (78.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+ + +  D+ S GDV+++RWK+++K+GGGGFGEIYE +D + +  VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR M  G+FS+STTL+L  QIL++IE+IHS+GFLHRDIKPSNFA+G  A T R  YMLDFGLARQF   + + +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG +K  YDH   L+ LP+EF  FL HI  LDYF KPDY+++ ++    MKS  V ++D +DWE
Sbjct:    1 MSGAVEHTDILSVGDVVRDRWKVVRKIGGGGFGEIYEVLDQLSQATVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMTRGTFSVSTTLRLGKQILEAIESIHSVGFLHRDIKPSNFAMGRLASTCRCCYMLDFGLARQFT--NSNQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKIKDKEQVGNLKETYDHKLMLKHLPSEFGTFLDHILTLDYFTKPDYQLLMSVFEKAMKSHNVLENDPYDWE 298

[Close]

BLAST of Tau tubulin kinase vs. TrEMBL
Match: A0A1A8N2T4 (Tau tubulin kinase 2 (Fragment) OS=Nothobranchius pienaari OX=704102 GN=TTBK2 PE=4 SV=1)

HSP 1 Score: 344.739 bits (883), Expect = 3.926e-104
Identity = 180/300 (60.00%), Postives = 233/300 (77.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+ + +  D+ S GDV+++RWK+ +K+GGGGFGEIYE +D + +  VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR M  G+FS+STTL+L  Q+L++IE+IHS+GFLHRDIKPSNFA+G  A T R  YMLDFGLARQF   + + +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKE VG++K  YDH   L+ LP EF  FL HI  LDY+ KPDY+++ ++  + MK+  V ++D +DWE
Sbjct:    1 MSGAVEHTDILSVGDVVRDRWKVARKIGGGGFGEIYEVLDQLSQATVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMTRGTFSVSTTLRLGKQMLEAIESIHSVGFLHRDIKPSNFAMGRLASTCRCCYMLDFGLARQFT--NSNQEVRPPRPVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKDKEHVGKLKDTYDHRLMLKHLPAEFGVFLEHIFSLDYYTKPDYQLLMSVFDNSMKTYNVVENDPYDWE 298

[Close]

BLAST of Tau tubulin kinase vs. TrEMBL
Match: V3ZM49 (Protein kinase domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_133319 PE=4 SV=1)

HSP 1 Score: 343.199 bits (879), Expect = 1.875e-103
Identity = 181/294 (61.56%), Postives = 227/294 (77.21%), Query Frame = 3

Query:  153 DLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWELN 1034
            DL S   ++K+RWK++KK+GGGGFGEIYE  D + K+ VA+KLES+K PKQVL+MEV+VLKKLQG  H C+  G GRN+K++YV M+LQGKNLA+LRR    G F +STTL+L  QIL +IE+IH +GFLHRDIKPSNF++G      R VYMLDFGLARQ+   + S +VRPPR  AGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E I GQLPWR++KDKEQVG +K  YDH + L+++P+EF+  L HIQ+L+Y+ KPDY M+ NL   CM+ K +  SD++DWE N
Sbjct:    5 DLLSPNQLVKDRWKVLKKIGGGGFGEIYEATDLVNKECVALKLESAKQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKYNYVVMSLQGKNLAELRRGQPKGCFGLSTTLRLGSQILKAIESIHDVGFLHRDIKPSNFSMGKPPSNSRKVYMLDFGLARQYT--NASGEVRPPRAAAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFIVGQLPWRKIKDKEQVGLMKEKYDHIQLLKNMPSEFRAILEHIQKLEYYDKPDYNMLHNLFEQCMRRKNIKDSDAYDWEKN 296

[Close]

BLAST of Tau tubulin kinase vs. TrEMBL
Match: R7V2U7 (Protein kinase domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_198680 PE=4 SV=1)

HSP 1 Score: 342.043 bits (876), Expect = 4.092e-103
Identity = 181/292 (61.99%), Postives = 221/292 (75.68%), Query Frame = 3

Query:  153 DLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            DL   G ++KERWK++KK+GGGGFGEIYE +D + K+ VA+KLES+K PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M+LQG+NLA+LRR    G F++ TTL+L  QIL  IE IHS+GFLHRDIKPSNFA+G     +  VYMLDFGLARQ+   +G  +VR PR  AGFRGTVRYAS++AH N EMGRHDDLWS FYM  E + GQLPWR+MKDKEQVG +K  YD   FL+ LP E KPFL HIQ LDY+ KPDY  ++ L+  CM+ K V + D +DWE
Sbjct:    5 DLLQVGHIVKERWKVVKKVGGGGFGEIYEALDMVSKESVALKLESAKQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMSLQGRNLAELRRNQSKGCFTVGTTLRLGTQILSGIEAIHSVGFLHRDIKPSNFAMGRLNNDKHKVYMLDFGLARQYTNTNG--EVRAPRAAAGFRGTVRYASLSAHKNKEMGRHDDLWSLFYMLVEFVMGQLPWRKMKDKEQVGNLKEKYDTGIFLKHLPAELKPFLEHIQSLDYYDKPDYNRLQGLLSQCMQRKGVKEDDPYDWE 294

[Close]

BLAST of Tau tubulin kinase vs. TrEMBL
Match: A0A267DEE2 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022436g3 PE=4 SV=1)

HSP 1 Score: 341.658 bits (875), Expect = 4.282e-103
Identity = 184/300 (61.33%), Postives = 226/300 (75.33%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M S T E DL + G ++K+RW++ KK+GGGGFGEIYE  D + K+ VA+KLES+K  KQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQGKNLA+LRR    GSF++STT++L  QIL++IE IHSIGFLHRDIKPSNF++G      R V+MLDFGLARQ+   DG   VR PR  AGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVG+IK  YDH++ L+ LP+EF+PFL H+ +L YF KPDY  +  L+  C K K +  S+ FDWE
Sbjct:    1 MNSVTSEADLLAVGSLVKDRWQVTKKIGGGGFGEIYEAQDVLNKEPVALKLESAKQAKQVLKMEVAVLKKLQGKDHVCRFLGCGRNDRFNYVVMELQGKNLAELRRSQPRGSFTVSTTVRLGRQILEAIEAIHSIGFLHRDIKPSNFSMGRGEPNCRKVFMLDFGLARQYTNSDGD--VRAPRVTAGFRGTVRYASVNAHQNREMGRHDDLWSLFYMLVEFACGQLPWRKLKDKEQVGRIKETYDHSQMLRYLPSEFRPFLEHVSKLAYFDKPDYRYLCGLLDQCAKRKSIRLSEPFDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Cavefish
Match: ttbk1a (tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-100609-4])

HSP 1 Score: 344.739 bits (883), Expect = 3.372e-102
Identity = 194/369 (52.57%), Postives = 255/369 (69.11%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWELNXXXXXXXXXXXNIDTNMERRNSAIISTGTGPQIHVAKSSRQNNGDVQNHVAIEEFRNKPSKTVKESV 1235
            M  S+++ D+     ++K+RWK++KK+GGGGFGEIYE VD + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H CK  G GRNDKF+YV M LQG+NLADLRR    G+F++STTL+L  QIL++IE IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQ+   +G  +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVGQ+K  YDH   L+ +P+EF  FL H+  LDY+ KPDY+++ ++  + MK + +T+++ +DWE    + T   ++SN  T    R +A +  G           R+N  DV     + +  N P     ES 
Sbjct:   30 MNGSSEQQDILPPNCMVKDRWKVLKKIGGGGFGEIYEAVDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILEAIEAIHSVGFLHRDIKPSNFAMGRLPSTVRKCYMLDFGLARQYTNTNG--EVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGQVKERYDHRMLLKHMPSEFHVFLDHVLALDYYTKPDYQLLMSVFENSMKERIITENELYDWE---KTGTDTMLTSNSATQQHTRPTAAMVGGVNVTPVPGDLQRENTDDVLQDEHLSDQENAPPAGRPEST 393

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Cavefish
Match: ttbk1b (tau tubulin kinase 1b [Source:ZFIN;Acc:ZDB-GENE-100609-5])

HSP 1 Score: 339.347 bits (869), Expect = 3.367e-100
Identity = 201/427 (47.07%), Postives = 277/427 (64.87%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWELNXXXXXXXXXXXNIDTNMERRNSAIISTGTGPQIHVAKSSRQNNGDVQNHVAIEEFRNKPSKTVKESVLKAKKSHLDMPDNGD--NGVSVGKSSYRHAVSNIAGKSEKSQNARNTMPPISPRSTFA 1403
            M  + ++ D+     ++KERWK++KK+GGGGFGEIYE +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG  H CK  G GRN+KF+YV M LQG+NLADLRR    G+FS+STTL+L  QIL+SIE IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQ+   +G  +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVGQIK  Y+H   L+ +P+EF  FL H+  LDY+ KPDY ++ ++  + MK +++T+++ FDWE     +     ++       R+ +AI+       +   +  R+N  DV     + +  N P   +     +A  +    P  G+  +     ++  R ++S     +E+ + A   + P+SPR   A
Sbjct:   14 MNGAGEQVDILPPNCMVKERWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFSMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTNG--EVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFTVGQLPWRKIKDKEQVGQIKERYEHKMLLKHMPSEFYIFLDHVLGLDYYTKPDYLLLMSVFENSMKEREITENEPFDWEKAGTDSLSSNSTATPPQQNTRQTAAIVGVVNVTPM-TGELPRENTDDVLQDEHLSDQENAPPVLLPIRPCEAALA----PPGGEAWDDTDFNRNKLRISISKTQVTAEEDEQA-GVVRPVSPRGGEA 432

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Cavefish
Match: ttbk2b (tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-030131-8246])

HSP 1 Score: 336.65 bits (862), Expect = 1.912e-97
Identity = 174/300 (58.00%), Postives = 224/300 (74.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+ + ++ D+ S G+V++ERW++    GG G    YE +D + +  VA+K+ES++ PKQVL+MEV+VLK+LQ   H C+  G GRND+F+YV M LQG+NLADLRR M  G+FS+STTL+L  QIL++IE+IHS+GFLHRDIKPSNFA+G  + T R  YMLDFGLARQF   +   +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG +K  YDH   L+ LP+EF  FL HI  LDYF KPDY+++ ++    MKS  V ++D +DWE
Sbjct:    1 MSGAAEQADILSVGNVVRERWRVKIGGGGFGEI--YEVLDQLNQCNVALKVESAQQPKQVLKMEVAVLKRLQ-KDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMSQGTFSVSTTLRLGRQILEAIESIHSVGFLHRDIKPSNFAMGRLSSTCRTCYMLDFGLARQFT--NSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKVKDKEQVGNLKETYDHHLMLKHLPSEFIVFLEHISNLDYFTKPDYQLLMSVFEKSMKSYNVMENDPYDWE 295

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Cavefish
Match: ttbk2b (tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-030131-8246])

HSP 1 Score: 293.123 bits (749), Expect = 1.585e-87
Identity = 162/300 (54.00%), Postives = 209/300 (69.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+ + ++ D+ S G+V++ERW++IKK+GGGGFGEIYE +D + +  VA+K+ES++ PKQVL+MEV+VLK+LQG  H C+  G GRND+F+YV M LQG+NLADLRR M  G+FS+STTL+L  QIL++IE+IHS+GFLHRDIKP                                     PR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG +K  YDH   L+ LP+EF  FL HI  LDYF KPDY+++ ++    MKS  V ++D +DWE
Sbjct:    1 MSGAAEQADILSVGNVVRERWRVIKKIGGGGFGEIYEVLDQLNQCNVALKVESAQQPKQVLKMEVAVLKRLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMSQGTFSVSTTLRLGRQILEAIESIHSVGFLHRDIKP-------------------------------------PRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKVKDKEQVGNLKETYDHHLMLKHLPSEFIVFLEHISNLDYFTKPDYQLLMSVFEKSMKSYNVMENDPYDWE 263

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Cavefish
Match: csnk1g1 (casein kinase 1 gamma 1 [Source:NCBI gene;Acc:103023720])

HSP 1 Score: 132.88 bits (333), Expect = 2.611e-32
Identity = 83/261 (31.80%), Postives = 138/261 (52.87%), Query Frame = 3

Query:  267 VAIKLESSKLPKQVLRMEVSVLKKLQGTKHAC-KCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETR-RIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDW 1025
            VAIKLE  K     L +E    K L  T     + Y +G   K++ + + L G +L DL   +   +FS+ T L + +Q++  +E +HS   ++RD+KP NF IG     +  I++++DFGLA++++ P+    + P R+     GT RY S+N H   E  R DDL +  +MF   + G LPW+ +K        +++G  K N       ++ P E   +L +++ LD+F+KPDYE ++ L  +  + K  T   ++DW
Sbjct:   70 VAIKLEPVKSRAPQLHLEYRFYKTLGSTAEGLPQVYYFGPCGKYNAMVLELLGPSLEDLF-DLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHIIHIIDFGLAKEYIDPETKKHI-PYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEVLCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTELFERKGYTFDYTYDW 328

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004926.1 (pep scaffold:Pmarinus_7.0:GL480178:196:11423:1 gene:ENSPMAG00000004461.1 transcript:ENSPMAT00000004926.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 262.692 bits (670), Expect = 4.443e-80
Identity = 129/225 (57.33%), Postives = 166/225 (73.78%), Query Frame = 3

Query:  354 HACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            H C+  G GRNDKF+YV M LQG+NLADLRR    G+FS+STTL+L  Q+L++IE+IH++GFLHRDIKPSNFA+G    T    +MLD+GLARQ+   + S +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVG IK  YDH   L+ +P +F  FL H+  LDY  +P+Y+ + +     M+ + +T+++ +DWE
Sbjct:    3 HVCRFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFSLSTTLRLGRQMLEAIESIHAVGFLHRDIKPSNFAMGRLPSTTHKCFMLDYGLARQYT--NSSGEVRPPRAVAGFRGTVRYASINAHRNKEMGRHDDLWSLFYMLVEFTVGQLPWRKIKDKEQVGLIKERYDHRLLLRHMPTDFHIFLDHVSTLDYCTRPNYQSIHSCALHIMRERSITENEPYDWE 225

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Sea Lamprey
Match: csnk1g2a (casein kinase 1, gamma 2a [Source:ZFIN;Acc:ZDB-GENE-030131-6445])

HSP 1 Score: 136.732 bits (343), Expect = 1.863e-34
Identity = 84/262 (32.06%), Postives = 141/262 (53.82%), Query Frame = 3

Query:  261 DKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIG-GSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDW 1025
            + VAIKLE  K     L +E    K+L   +   + Y +G   K++ + + L G +L DL   + + +F++ T L + +Q+L  +E +HS   ++RD+KP NF IG  S   + I++++DFGLA++++ P+    + P R+     GT RY S+N H   E  R DDL +  +MF   + G LPW+ +K        +++G  K         ++ P E   +L +++ LD+F++PDYE M+NL  D  + K  +    FDW
Sbjct:   62 EYVAIKLEPMKSRAPQLHLEYRFYKQLGNAEGVPQVYYFGPCGKYNAMVLELLGPSLEDLF-DLCNRTFTLKTVLMIAIQLLTRMEYVHSRNLIYRDVKPENFLIGRQSTNKQHIIHIIDFGLAKEYIDPETKKHI-PYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFERPDYEYMRNLFMDLFERKGYSFDYEFDW 321

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008477.1 (pep scaffold:Pmarinus_7.0:GL482342:316:9736:-1 gene:ENSPMAG00000007664.1 transcript:ENSPMAT00000008477.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 116.701 bits (291), Expect = 3.490e-28
Identity = 85/261 (32.57%), Postives = 130/261 (49.81%), Query Frame = 3

Query:  261 DKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDW 1025
            ++VAIKLE  K     L +E  + K LQG          G    ++ + M L G ++ DL     S  FS+ T L L  Q++  IE +HS  F+HRDIKP NF +G   +   +VY++D GLA+++     + Q  P R+     GT RYAS+N H  +E  R DDL S  Y+      G LPW+ +K        E++ + K++       ++ P+EF  +L   + L +  KPDY  ++ L R+    +  +    FDW
Sbjct:   34 EEVAIKLECVKTKHPQLHIESKIYKLLQGGVGIPVIKWCGAEGDYNVMVMELLGPSMEDLF-NFCSRKFSLKTVLLLADQMISRIEYLHSKNFIHRDIKPDNFLMG-LGKKGNLVYIIDLGLAKKYR-DSRTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEMLCKTYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 291

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Sea Lamprey
Match: csnk1g1 (casein kinase 1, gamma 1 [Source:NCBI gene;Acc:494092])

HSP 1 Score: 93.5893 bits (231), Expect = 2.271e-21
Identity = 61/189 (32.28%), Postives = 104/189 (55.03%), Query Frame = 3

Query:  261 DKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRI-VYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMK 824
            + VAIKLE  K     L +E    K+L   +   + Y +G   K++ + + L G +L DL   +   +FS+ T L + +Q++  +E +HS   ++RD+KP NF +G    ++   ++++DFGLA++++ P+    + P R+     GT RY S+N H   E  R DDL +  +MF   + G LPW+ +K
Sbjct:   56 EYVAIKLEPMKSRAPQLHLEYRFYKQLGNAEGVPQVYYFGPCGKYNAMVLELLGPSLEDLF-DLCDRTFSLKTVLMIAMQLISRMEYVHSRSLIYRDVKPENFLVGRQGTSKHHNIHIIDFGLAKEYIDPETKKHI-PYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLK 242

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001691.1 (pep scaffold:Pmarinus_7.0:GL476581:539457:546336:1 gene:ENSPMAG00000001522.1 transcript:ENSPMAT00000001691.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.0258 bits (188), Expect = 5.102e-16
Identity = 59/169 (34.91%), Postives = 91/169 (53.85%), Query Frame = 3

Query:  234 YECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVE 740
            Y  ++    ++VA+KLES K     L  E  + K LQG         YG+   ++ + M L G +L DL     S  F++ T L L  Q++  IE +H+  F+HRDIKP NF +G      ++ +++DFGLA+++   + + Q  P R+     GT RYAS+NAH  +E
Sbjct:   32 YLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLF-NFCSRRFTMKTVLMLADQMISRIEYVHNKNFIHRDIKPDNFLMGIGRHCNKL-FLIDFGLAKKY-RDNRTRQHIPYREDKNLTGTARYASINAHLGIE 197

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Yeast
Match: HRR25 (Conserved casein kinase; regulates diverse events including: vesicular traffic, DNA repair, the CVT pathway, monopolar attachment of sister kinetochores at meiosis I, and ribosomal subunit biogenesis; monopolin subunit; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p, the kinetochore receptor for monopolin; homolog of mammalian CK1delta [Source:SGD;Acc:S000006125])

HSP 1 Score: 114.39 bits (285), Expect = 9.844e-27
Identity = 85/272 (31.25%), Postives = 132/272 (48.53%), Query Frame = 3

Query:  234 YECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWEL 1031
            Y   + I  ++VAIKLES +     L  E  V + L G         +GR  +++ + + L G +L DL        FS  T + L LQ+   I+ IH   F+HRDIKP NF +G        V+++DFGL++++   +    + P R+     GT RYAS+N H  +E  R DDL S  Y+      G LPW+ +K        +++ + KLN         LP EF+ ++A+ + L + +KPDY  +  L +D     +      FDW +
Sbjct:   24 YHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHR-RFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMG-VGRRGSTVHVIDFGLSKKYRDFNTHRHI-PYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTM 292

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Yeast
Match: YCK1 (Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK1 has a paralog, YCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001177])

HSP 1 Score: 114.39 bits (285), Expect = 1.163e-26
Identity = 83/272 (30.51%), Postives = 136/272 (50.00%), Query Frame = 3

Query:  234 YECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIG--GSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDW 1025
            +E  + I    VAIK E  K     LR E    K L GT +    Y +G+    + + + L G +L DL        FS+ T +Q+ +Q++  IE++H+   ++RDIKP NF IG  G  +   I +++DFG+A+Q+  P     + P R+     GT RY S+N H   E  R DD+ +  ++F+  + G LPW+ +K        E++G+ K + +     Q LP +F  +L  ++ L + + PDYE  + L+   +     T    +DW
Sbjct:   84 FEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGR-KFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNI-HLIDFGMAKQYRDPKTKQHI-PYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQGLPVQFGRYLEIVRSLSFEECPDYEGYRKLLLSVLDDLGETADGQYDW 352

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Yeast
Match: YCK2 (Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK2 has a paralog, YCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005098])

HSP 1 Score: 113.62 bits (283), Expect = 2.775e-26
Identity = 85/277 (30.69%), Postives = 139/277 (50.18%), Query Frame = 3

Query:  234 YECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADL-----RRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIG--GSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDW 1025
            +E  + I    VAIK E  K     L+ E    K L GT    + Y +G+    + + + L G +L DL     RR      FS+ T +Q+ +Q++  IE++H+   ++RDIKP NF IG  G  +  + V+++DFG+A+Q+  P     + P R+     GT RY S+N H   E  R DD+ +  ++F+  + GQLPW+ +K        E++G+ K   +     Q LP +F  +L  ++ L + + PDYE  + L+   +     T    +DW
Sbjct:   91 FEGTNMINGLPVAIKFEPRKTEAPQLKDEYRTYKILAGTPGIPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGRR------FSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANK-VHLIDFGMAKQYRDPKTKQHI-PYREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLKAPNNKQKYEKIGEKKRLTNVYDLAQGLPIQFGRYLEIVRNLSFEETPDYEGYRMLLLSVLDDLGETADGQYDW 359

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Yeast
Match: YCK3 (Palmitoylated vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway [Source:SGD;Acc:S000000925])

HSP 1 Score: 106.686 bits (265), Expect = 3.855e-24
Identity = 80/283 (28.27%), Postives = 130/283 (45.94%), Query Frame = 3

Query:  252 IVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIG-----------------GSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMK------DKEQVGQI--KLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDW 1025
            +  + VAIK E        LR E    + L G       Y +G+    + + + L G +L DL  +     FS+ TT  +  Q++D +  IH    ++RDIKP NF I                   S     ++YM+DFG+A+Q+  P     + P R+     GT RY S+N H   E  R DDL S  ++F+  + G LPW+ +K        E++G    KLN D      ++P +F  +L + + L + + PDY+ + +L+ D ++   +     +DW
Sbjct:   52 MANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLF-EWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHI-PYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYLISLMDDALRLNDLKDDGHYDW 332

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Yeast
Match: MPS1 (Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p [Source:SGD;Acc:S000002186])

HSP 1 Score: 58.5362 bits (140), Expect = 7.232e-9
Identity = 52/227 (22.91%), Postives = 96/227 (42.29%), Query Frame = 3

Query:  318 EVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPD-----------GSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMK 965
            E+ +L+KL+  K   +   Y   D   Y+ M     +L+ +  Q        +     T ++L  I+ +H  G +H D+KP+NF +      + I+ ++DFG+A    +P+           G+     P  +     T    + +  N  ++GR  D+WS   + Y+MI G+ P+   + + ++  I +N          P+   PF  H    +   K   E+MK
Sbjct:  486 EIELLEKLKDQKRVIQLLDYEMGDGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVL-----VKGILKIIDFGIAN--AVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAI-MN----------PDVKIPFPEHTSNNEKIPKSAIELMK 694

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Nematostella
Match: EDO46789 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP40])

HSP 1 Score: 323.553 bits (828), Expect = 2.211e-100
Identity = 177/292 (60.62%), Postives = 217/292 (74.32%), Query Frame = 3

Query:  153 DLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            DL   GDV+++RWKIIKK+GGGGFGEIY  +D + KD VAIKLES    KQVL+MEV+VLKKLQG  H CK    GRN+ F+Y+ M+LQG NLA+LRR    G FS ST L+L  QIL S+++IH  GFLHRDIKPSNFA+G + +T  I YMLDFGL+RQF   +G  +VRPPR+ AGFRGTVRYAS+NAH N EMGRHDDLWS FY+  E   GQLPWR+MKDKEQVG++K  YD    L+S+P EFK F+ HI +L Y  KPDY+M+  L+   +K K + +SD +DWE
Sbjct:    3 DLLKPGDVVRQRWKIIKKIGGGGFGEIYRGLDQVTKDYVAIKLESVHQSKQVLKMEVAVLKKLQGVDHICKFISCGRNESFNYLVMSLQGSNLAELRRSQPKGVFSHSTMLRLGTQILKSVKSIHEAGFLHRDIKPSNFAMGNTPDTVHICYMLDFGLSRQFTKANG--EVRPPRNTAGFRGTVRYASINAHENKEMGRHDDLWSFFYLMVEFTVGQLPWRKMKDKEQVGKMKKTYDIANLLKSMPGEFKQFVDHISKLKYEDKPDYKMLLGLLEQIIKRKGIKESDPYDWE 292

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Nematostella
Match: EDO34289 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPP6])

HSP 1 Score: 133.265 bits (334), Expect = 1.040e-32
Identity = 87/262 (33.21%), Postives = 138/262 (52.67%), Query Frame = 3

Query:  261 DKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIG-GSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDW 1025
            + VAIKLE  K     L +E    K L   +   + + +G   K++ + M L G +L DL   + +  FS+ T L + LQ++  IE +HS   ++RDIKP NF IG  SA   + + ++DFGLA++++ P+    + P R+     GT RY S+N H   E  R DDL +  +MF   + G LPW+ +K        +++G  K         ++ P E   +L +++ LD+F+ PDYE ++ L RD M+ K   +   FDW
Sbjct:   70 EHVAIKLEPMKSRAPQLHLEYRFYKALGNAEGIPQVHYFGPCGKYNALVMELLGPSLEDLF-DLCNRQFSLKTVLMVALQLISRIEYVHSKNMIYRDIKPENFLIGRKSAGKEKTINIIDFGLAKEYIDPETKKHI-PYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENHPEEMATYLRYVRRLDFFETPDYEYLRKLFRDLMERKGYVEDFEFDW 329

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Nematostella
Match: EDO34742 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNG2])

HSP 1 Score: 124.405 bits (311), Expect = 3.011e-30
Identity = 89/263 (33.84%), Postives = 131/263 (49.81%), Query Frame = 3

Query:  261 DKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWEL 1031
            ++VAIKLE  K     L +E    K +QG          G    ++ + M L G +L DL     +  FSI T L L  Q +  IE +HS  F+HRDIKP NF +G   +   +VY++DFGLA+++  P  + Q  P R+     GT RYAS+N H  +E  R DDL S  Y+      G LPW+ +K        E++ + K++       +  P+EF  +L + + L +  KPDY  ++ L R+    +  T    FDW L
Sbjct:   33 EEVAIKLECVKTKHPQLHIEAKFYKMMQGGVGIPTIKWCGTEGDYNVLVMELLGPSLEDLF-NFCNRKFSIKTVLLLADQTISRIEYVHSKNFIHRDIKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDPR-THQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGFPSEFATYLNNCRSLRFDDKPDYSYLRQLFRNLFHRQGYTYDYVFDWNL 292

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Nematostella
Match: EDO46523 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPJ6])

HSP 1 Score: 114.005 bits (284), Expect = 3.599e-27
Identity = 83/272 (30.51%), Postives = 134/272 (49.26%), Query Frame = 3

Query:  234 YECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWEL 1031
            Y  ++    ++VA+KLES K     L  E  + K LQG         YG+   ++ + M L G +L DL     S  F++ T L L  Q++  IE +H+  F+HRDIKP NF +G      ++ +++DFGLA+++     + Q  P R+     GT RYAS+NAH  +E  R DD+ S  Y+        LPW+ +K        E++ + K++       +  P EF  +L + + L + + PDY  ++ L R   ++        FDW +
Sbjct:   34 YLAINTTNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPSVRYYGQERDYNVLVMELLGPSLEDLF-NFCSRRFTMKTVLMLADQMISRIEYVHNKNFIHRDIKPDNFLMGVGKHCNKL-FLIDFGLAKKY-RDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNYQYDYIFDWTM 302

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Nematostella
Match: EDO48738 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIM1])

HSP 1 Score: 103.605 bits (257), Expect = 9.926e-24
Identity = 80/270 (29.63%), Postives = 130/270 (48.15%), Query Frame = 3

Query:  234 YECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDW 1025
            Y CV     ++ A+KLES K     L  E  + K L G         + + + ++ + M L G +L DL     +  F++ T L L  Q++  IE +H+  F+HRDIKP NF +G      ++ Y++DFGLA+++     + Q    R+     GT RYAS+NAH  +E  R DD+ S  Y+        LPW+ +K        E++ + K++       +  P EF  +L + + L + + PDY  ++ L R   ++        FDW
Sbjct:   29 YLCVHTENGEEKAVKLESQKARHPQLLYESKLYKILAGGSGIPAIRHFSQENDYNVLVMDLLGPSLEDLF-NFCNRKFNMKTVLMLADQMIARIEYVHNKNFIHRDIKPDNFLMGIGRHCNKL-YLIDFGLAKKYR-DSRTKQHISYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRSNLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFSMYLNYCKGLRFEEAPDYMYLRQLFRILFRTLNHQYDYIFDW 295

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Medaka
Match: ttbk2a (tau tubulin kinase 2 [Source:NCBI gene;Acc:101174145])

HSP 1 Score: 326.635 bits (836), Expect = 2.419e-92
Identity = 180/302 (59.60%), Postives = 229/302 (75.83%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQ-GKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKP-SNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   +  D+ S   ++KERWK+++K+GGGGFGEIYE +D + +  VA+K+ES++ PKQVL+MEV+VLKKLQ   H C+  G GRND+F+YV M LQ G+NLADLRR M  G+FSISTTL+L  QIL++IE+IHS+GFLHRDIKP SNFA+G    T R  YMLDFGLARQF   +   +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++K+KEQVG++K  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + MK+  V ++D +DWE
Sbjct:    1 MSGGVEPADILSVLSLVKERWKVVRKIGGGGFGEIYEAMDLLTRASVALKVESAQQPKQVLKMEVAVLKKLQ-KDHICRFVGCGRNDRFNYVVMELQQGRNLADLRRSMPRGTFSISTTLRLGHQILEAIESIHSVGFLHRDIKPQSNFAMGRFPSTCRTCYMLDFGLARQFT--NSCQEVRPPRPVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKEKEQVGKLKETYDHCLMLRHLPAEFGVFLDHISNLDYFTKPDYQLLMSVFDNSMKTYNVVENDPYDWE 299

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Medaka
Match: ttbk1a (tau tubulin kinase 1 [Source:NCBI gene;Acc:105354132])

HSP 1 Score: 306.99 bits (785), Expect = 5.886e-89
Identity = 169/304 (55.59%), Postives = 225/304 (74.01%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGT----KHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M  ++++ D+     ++K+RWK++KK+GGGGFGEIYE +D + ++ VA+K+ES++ PKQVL+MEV+VLKKLQG     +H      +  N  F +V +  QG+NLADLRR    G+F++STTL+L  QIL+SIE IHS+GFLHRDIKPSNFA+G    T R  YMLDFGLARQ+   +G  +VRPPR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E   GQLPWR++KDKEQVGQIK  +DH   L+ +P+EF  FL H+  LDY+ KPDY+++ ++  + MK + +T+++ FDWE
Sbjct:   14 MNGTSEQADILPPNCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGETLLHEHEDPVVSFLGNKLFFFVWLA-QGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTNG--EVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGQIKERFDHKMLLKHMPSEFSIFLDHVLALDYYTKPDYQLLMSVFENSMKERIITENEPFDWE 314

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Medaka
Match: ttbk2b (tau-tubulin kinase 2 [Source:NCBI gene;Acc:101157747])

HSP 1 Score: 292.352 bits (747), Expect = 3.380e-87
Identity = 162/300 (54.00%), Postives = 205/300 (68.33%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M       D+ + GDV+++RWK+I+K+GGGGFGEIYE +D + +  VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR M  G+FS+STTL+L  QIL++IE+IHS+GFLHRDIKP                                     PR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++KDKEQVG +K  YDH   L+ LP+EF  FL HI  LDYF KPDY+++ ++    MKS  V ++D +DWE
Sbjct:    1 MNGGVDHTDILTVGDVVRDRWKVIRKIGGGGFGEIYEVLDQLSQATVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMSRGTFSVSTTLRLGKQILEAIESIHSVGFLHRDIKP-------------------------------------PRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKIKDKEQVGNLKETYDHRLMLKHLPSEFSTFLDHIMTLDYFTKPDYQLLTSMFDSAMKSHNVLENDPYDWE 263

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Medaka
Match: ttbk2a (tau tubulin kinase 2 [Source:NCBI gene;Acc:101174145])

HSP 1 Score: 285.804 bits (730), Expect = 7.705e-85
Identity = 160/300 (53.33%), Postives = 206/300 (68.67%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M+   +  D+ S   ++KERWK+++K+GGGGFGEIYE +D + +  VA+K+ES++ PKQVL+MEV+VLKKLQG  H C+  G GRND+F+YV M LQG+NLADLRR M  G+FSISTTL+L  QIL++IE+IHS+GFLHRDIKP                                     PR VAGFRGTVRYAS+NAH N EMGRHDDLWS FYM  E + GQLPWR++K+KEQVG++K  YDH   L+ LP EF  FL HI  LDYF KPDY+++ ++  + MK+  V ++D +DWE
Sbjct:    1 MSGGVEPADILSVLSLVKERWKVVRKIGGGGFGEIYEAMDLLTRASVALKVESAQQPKQVLKMEVAVLKKLQGKDHICRFVGCGRNDRFNYVVMELQGRNLADLRRSMPRGTFSISTTLRLGHQILEAIESIHSVGFLHRDIKP-------------------------------------PRPVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKEKEQVGKLKETYDHCLMLRHLPAEFGVFLDHISNLDYFTKPDYQLLMSVFDNSMKTYNVVENDPYDWE 263

[Close]

BLAST of Tau tubulin kinase vs. Ensembl Medaka
Match: csnk1g1 (casein kinase 1 gamma 1 [Source:NCBI gene;Acc:101164710])

HSP 1 Score: 132.109 bits (331), Expect = 3.654e-32
Identity = 81/260 (31.15%), Postives = 139/260 (53.46%), Query Frame = 3

Query:  267 VAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRR-IVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDK------EQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDW 1025
            VAIKLE  K     L +E    K L  ++   + + +G   K++ + + L G +L DL   +   +FS+ T L + +Q++  +E +HS   ++RD+KP NF IG     +  I++++DFGLA++++ P+    + P R+     GT RY S+N H   E  R DDL +  +MF   + G LPW+ +K        +++G  K N       ++ P E   +L +++ LD+F+KPDYE ++ L  +  + K  T   ++DW
Sbjct:   77 VAIKLEPVKSRAPQLHLEYRFYKTLGTSEGVPQVFYFGPCGKYNAMVLELLGPSLEDLF-DLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHIIHIIDFGLAKEYIDPETKKHI-PYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEVLCENFPEEMATYLRYVRRLDFFEKPDYEYLRALFTELFERKGYTFDYTYDW 334

[Close]

BLAST of Tau tubulin kinase vs. Planmine SMEST
Match: SMESG000026133.1 (SMESG000026133.1)

HSP 1 Score: 2329.29 bits (6035), Expect = 0.000e+0
Identity = 1333/1333 (100.00%), Postives = 1333/1333 (100.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWELNXXXXXXXXXXXNIDTNMERRNSAIISTGTGPQIHVAKSSRQNNGDVQNHVAIEEFRNKPSKTVKESVLKAKKSHLDMPDNGDNGVSVGKSSYRHAVSNIAGKSEKSQNARNTMPPISPRSTFANQKEKMFDIKFSEEIETPRNAVQSEITSHEKHSSVIDSHXXXXXXXXXXEPELVNKPSRLPVLMKTXXXXXXXXXXEYEPDQPFFQNHKTTEDSVLFADNYETNFESENQKHRGISAALAVVPNSMKVTGNLPPKPATSSTPSNLVKNTEKLNKNSINLRGNFLQSVGGSVATHAVNDDQFDVSNAPDATKAVLLSNQXXXXXXXXXXXLSDHFEDDKYHVNQFKQQESDTKENTATKDSKLNGQIKPQSYISSGDNLSTTNHNDSSKRSRRQPMIVTEKSSAKIQAQLADKSRASSSILSRLNNQEEDSSNCKSKESHEMEMTLSKAKTTTTSGYISSVSKYDVNQKPSYEAIGQSGDDKNHNYLSQRHPYYGVVDSTSCSASANVLSHKHNNEMQKSNSNISRLPPKSSEQRYKVNKYSTNQDTSDLSISRSSRRNGASKSNHQNSSSNPKSGFHISSKDSANKHNYYDLKRSSNLQFSNHHTFQNLNHSDHGVIVSQGTYNSSNHHNSRRDPSNFNNHQSDLKLGMKDHSSSSRTFDSYRDSDRPTPKPRSHHRSQSHTNREVANSIINGHGDSTIIRQKXXXXXXXXXXXXXXXXXXXXXXHSFDRYNLXXXXXXXXXXXXXXNNKKPNPTSSGSQKPVVCKHXXXXXXXXXXXXXXXXDCVQCQNYGVKKCTTHYSQKXXXXXXXXXXXXXXXXANSLTRSGSIVMKSKSDLNLSMAGLIQNRHSGKGQRSSHGKAQHXXXXXXXXXXXXTAKNYSTSPNHRTDSSIHRXXXXXXXXXXXADLLNHYLRHSKTLSNSNMQNKSSKPHQHVQSSSNSILKPKPKPNPHGQYNNMSTSTSVTSGIHRHVYKKXXXXXXXXXXXXXXXXTTSTTNQANSSFNPKPPSSGKYHQTHVFRNRQYTSTK 4127
            MTSSTQEPDLASEGDVIKERWKIIKKLGGGGFGEIYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFSISTTLQLTLQILDSIENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWELNSVSTTPVTVSSNIDTNMERRNSAIISTGTGPQIHVAKSSRQNNGDVQNHVAIEEFRNKPSKTVKESVLKAKKSHLDMPDNGDNGVSVGKSSYRHAVSNIAGKSEKSQNARNTMPPISPRSTFANQKEKMFDIKFSEEIETPRNAVQSEITSHEKHSSVIDSHNRSASRRNRREPELVNKPSRLPVLMKTSSSDSNNKSNEYEPDQPFFQNHKTTEDSVLFADNYETNFESENQKHRGISAALAVVPNSMKVTGNLPPKPATSSTPSNLVKNTEKLNKNSINLRGNFLQSVGGSVATHAVNDDQFDVSNAPDATKAVLLSNQECDDDDEDNCNLSDHFEDDKYHVNQFKQQESDTKENTATKDSKLNGQIKPQSYISSGDNLSTTNHNDSSKRSRRQPMIVTEKSSAKIQAQLADKSRASSSILSRLNNQEEDSSNCKSKESHEMEMTLSKAKTTTTSGYISSVSKYDVNQKPSYEAIGQSGDDKNHNYLSQRHPYYGVVDSTSCSASANVLSHKHNNEMQKSNSNISRLPPKSSEQRYKVNKYSTNQDTSDLSISRSSRRNGASKSNHQNSSSNPKSGFHISSKDSANKHNYYDLKRSSNLQFSNHHTFQNLNHSDHGVIVSQGTYNSSNHHNSRRDPSNFNNHQSDLKLGMKDHSSSSRTFDSYRDSDRPTPKPRSHHRSQSHTNREVANSIINGHGDSTIIRQKNNYYTSSINNMNNNLSPNDMNDHSFDRYNLRPRSSSRESISKYSNNKKPNPTSSGSQKPVVCKHNSSPSRRRSTSFNNNNDCVQCQNYGVKKCTTHYSQKNNSNLVLNTNSSGVLVANSLTRSGSIVMKSKSDLNLSMAGLIQNRHSGKGQRSSHGKAQHSSQSPSVVSQYSTAKNYSTSPNHRTDSSIHRSLTSSINRSSSADLLNHYLRHSKTLSNSNMQNKSSKPHQHVQSSSNSILKPKPKPNPHGQYNNMSTSTSVTSGIHRHVYKKVIREDSVDSDISVSHITTSTTNQANSSFNPKPPSSGKYHQTHVFRNRQYTSTK
Sbjct:    1 MTSSTQEPDLASEGDVIKERWKIIKKLGGGGFGEIYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFSISTTLQLTLQILDSIENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWELNSVSTTPVTVSSNIDTNMERRNSAIISTGTGPQIHVAKSSRQNNGDVQNHVAIEEFRNKPSKTVKESVLKAKKSHLDMPDNGDNGVSVGKSSYRHAVSNIAGKSEKSQNARNTMPPISPRSTFANQKEKMFDIKFSEEIETPRNAVQSEITSHEKHSSVIDSHNRSASRRNRREPELVNKPSRLPVLMKTSSSDSNNKSNEYEPDQPFFQNHKTTEDSVLFADNYETNFESENQKHRGISAALAVVPNSMKVTGNLPPKPATSSTPSNLVKNTEKLNKNSINLRGNFLQSVGGSVATHAVNDDQFDVSNAPDATKAVLLSNQECDDDDEDNCNLSDHFEDDKYHVNQFKQQESDTKENTATKDSKLNGQIKPQSYISSGDNLSTTNHNDSSKRSRRQPMIVTEKSSAKIQAQLADKSRASSSILSRLNNQEEDSSNCKSKESHEMEMTLSKAKTTTTSGYISSVSKYDVNQKPSYEAIGQSGDDKNHNYLSQRHPYYGVVDSTSCSASANVLSHKHNNEMQKSNSNISRLPPKSSEQRYKVNKYSTNQDTSDLSISRSSRRNGASKSNHQNSSSNPKSGFHISSKDSANKHNYYDLKRSSNLQFSNHHTFQNLNHSDHGVIVSQGTYNSSNHHNSRRDPSNFNNHQSDLKLGMKDHSSSSRTFDSYRDSDRPTPKPRSHHRSQSHTNREVANSIINGHGDSTIIRQKNNYYTSSINNMNNNLSPNDMNDHSFDRYNLRPRSSSRESISKYSNNKKPNPTSSGSQKPVVCKHNSSPSRRRSTSFNNNNDCVQCQNYGVKKCTTHYSQKNNSNLVLNTNSSGVLVANSLTRSGSIVMKSKSDLNLSMAGLIQNRHSGKGQRSSHGKAQHSSQSPSVVSQYSTAKNYSTSPNHRTDSSIHRSLTSSINRSSSADLLNHYLRHSKTLSNSNMQNKSSKPHQHVQSSSNSILKPKPKPNPHGQYNNMSTSTSVTSGIHRHVYKKVIREDSVDSDISVSHITTSTTNQANSSFNPKPPSSGKYHQTHVFRNRQYTSTK 1333

[Close]

BLAST of Tau tubulin kinase vs. Planmine SMEST
Match: SMESG000030545.1 (SMESG000030545.1)

HSP 1 Score: 380.948 bits (977), Expect = 2.251e-111
Identity = 195/300 (65.00%), Postives = 243/300 (81.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M S+ QE DL +  +++K+RWK+I+KLGGGGFGEIYEC+D   ++KVA+KLESS++ KQVL+MEV+VLKKLQGT H CK  G GRND+F+YVAMTLQGKNLADLRR  K+ +FSIST L+L+ QIL SI++IH+ GFLHRDIKPSNF++G    +   V MLDFGLARQ++LPDG+  +R PR V GFRGTVRYAS+NAH N EMGRHDDLWSAFYM  EM+TG LPWR++KDK+QVGQIK N++HT+ L+ LP+EFK  L+HIQ L YF  PDYE +KNLI  CM+ K ++  + FDWE
Sbjct:    1 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 300

[Close]

BLAST of Tau tubulin kinase vs. Planmine SMEST
Match: SMESG000048011.1 (SMESG000048011.1)

HSP 1 Score: 357.836 bits (917), Expect = 5.519e-110
Identity = 187/300 (62.33%), Postives = 237/300 (79.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M S +   DL   G+V+K+RW++I+K+GGGGFGEIYE  D   +D+VA+KLESS+ PKQVL+MEV+VLKK+QG +H+C+  G GRND+F+Y+ M+LQG+NLA+LRR    G FS+ST L+L  QILDSIE IH +GFLHRD+KPSNFA+G   +T RIVY+LDFGL+RQ++  D   +VR PR +AGFRGTVRYAS NAH N EMGRHDDLWS FYM  EM+TGQLPWR++KDKEQVGQIK ++DHT  L+ LP+EF+ FL H+Q L YF  PDY M++NL  +CM  K+V +SD FDWE
Sbjct:    1 MGSESDSSDLLQAGNVVKDRWRVIRKIGGGGFGEIYEAFDEATQDRVALKLESSRQPKQVLKMEVAVLKKIQGREHSCRFVGCGRNDRFNYLVMSLQGRNLAELRRNTPRGIFSVSTMLKLGRQILDSIETIHMVGFLHRDVKPSNFAMGRLPQTARIVYILDFGLSRQYLNVDD--EVRTPRPIAGFRGTVRYASTNAHMNREMGRHDDLWSMFYMLVEMVTGQLPWRKLKDKEQVGQIKQSFDHTILLRHLPSEFRLFLEHVQSLTYFDSPDYTMLRNLFDECMLRKRVHESDLFDWE 298

[Close]

BLAST of Tau tubulin kinase vs. Planmine SMEST
Match: SMESG000030545.1 (SMESG000030545.1)

HSP 1 Score: 379.407 bits (973), Expect = 1.282e-109
Identity = 195/300 (65.00%), Postives = 243/300 (81.00%), Query Frame = 3

Query:  129 MTSSTQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE 1028
            M S+ QE DL +  +++K+RWK+I+KLGGGGFGEIYEC+D   ++KVA+KLESS++ KQVL+MEV+VLKKLQGT H CK  G GRND+F+YVAMTLQGKNLADLRR  K+ +FSIST L+L+ QIL SI++IH+ GFLHRDIKPSNF++G    +   V MLDFGLARQ++LPDG+  +R PR V GFRGTVRYAS+NAH N EMGRHDDLWSAFYM  EM+TG LPWR++KDK+QVGQIK N++HT+ L+ LP+EFK  L+HIQ L YF  PDYE +KNLI  CM+ K ++  + FDWE
Sbjct:    1 MPSTKQETDLLNPSNIVKDRWKVIRKLGGGGFGEIYECLDSHTQEKVALKLESSRIAKQVLKMEVAVLKKLQGTAHVCKFLGCGRNDRFNYVAMTLQGKNLADLRRAQKNSAFSISTMLRLSAQILQSIQDIHNSGFLHRDIKPSNFSMGRLPLSSHTVVMLDFGLARQYILPDGNGDIRAPRPVTGFRGTVRYASVNAHMNREMGRHDDLWSAFYMMAEMVTGSLPWRKLKDKDQVGQIKQNFEHTQLLRHLPSEFKLLLSHIQSLTYFDAPDYEYLKNLIYQCMRRKGISSDELFDWE 300

[Close]

BLAST of Tau tubulin kinase vs. Planmine SMEST
Match: SMESG000068893.1 (SMESG000068893.1)

HSP 1 Score: 345.125 bits (884), Expect = 1.784e-101
Identity = 184/298 (61.74%), Postives = 227/298 (76.17%), Query Frame = 3

Query:  138 STQEPDLASEGDVIKERWXXXXXXXXXXXXXXYECVDPIVKDKVAIKLESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKNLADLRRQMKSGSFXXXXXXXXXXXXXXXXENIHSIGFLHRDIKPSNFAIGGSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAHNNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFLQSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWEL 1031
            ++   DL   G +IKERW++ KK+GGGGFG+IYE +D   ++KVA+KLES++  KQVL+MEV+VLKKLQG  H C+ YG GRNDKF+YV M+LQGKNL +LRR    G FSIS+ ++LT Q+L+ IE+IHS+GFLHRDIKPSNFA+G    T R VYMLDFGLARQ+V  DG  +VRPPR VAGFRGTVRYAS NAH N E+GRHDDLWS  Y+  EM+TGQLPWR++KDKEQVG++K N DH   L+ +P EFK  L HIQEL YF KPDY  ++NL+   M  K    +D FDWE+
Sbjct:    5 TSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDG--EVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEI 300

The following BLAST results are available for this feature:

BLAST of Tau tubulin kinase vs. Ensembl Human
BLAST of Tau tubulin kinase vs. Ensembl Celegans
BLAST of Tau tubulin kinase vs. Ensembl Fly
BLAST of Tau tubulin kinase vs. Ensembl Zebrafish
BLAST of Tau tubulin kinase vs. Ensembl Xenopus
BLAST of Tau tubulin kinase vs. Ensembl Mouse
BLAST of Tau tubulin kinase vs. UniProt/SwissProt
BLAST of Tau tubulin kinase vs. TrEMBL
BLAST of Tau tubulin kinase vs. Ensembl Cavefish
BLAST of Tau tubulin kinase vs. Ensembl Sea Lamprey
BLAST of Tau tubulin kinase vs. Ensembl Yeast
BLAST of Tau tubulin kinase vs. Ensembl Nematostella
BLAST of Tau tubulin kinase vs. Ensembl Medaka
BLAST of Tau tubulin kinase vs. Planmine SMEST

BLAST of Tau tubulin kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TTBK2	1.909e-103	61.33	tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:...	[more]
TTBK2	1.557e-97	61.00	tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:...	[more]
TTBK1	1.105e-95	59.00	tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:...	[more]
TTBK1	3.865e-95	60.69	tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:...	[more]
TTBK2	2.684e-85	54.00	tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Tau tubulin kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttbk-7	8.589e-89	51.65	Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:Q...	[more]
R13H9.5	4.858e-52	40.19	pep chromosome:WBcel235:IV:5065746:5066987:-1 gene...	[more]
ttbk-2	7.340e-52	40.19	Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:O...	[more]
F35C11.3	1.864e-50	36.84	pep chromosome:WBcel235:II:8246776:8248263:1 gene:...	[more]
M05D6.1	2.031e-50	36.84	pep chromosome:WBcel235:II:8473819:8475406:-1 gene...	[more]

BLAST of Tau tubulin kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Asator	4.985e-99	61.99	gene:FBgn0039908 transcript:FBtr0300344	[more]
Asator	9.565e-97	61.99	gene:FBgn0039908 transcript:FBtr0344869	[more]
Asator	9.565e-97	61.99	gene:FBgn0039908 transcript:FBtr0332908	[more]
Asator	2.062e-96	61.99	gene:FBgn0039908 transcript:FBtr0332904	[more]
Asator	2.922e-96	61.99	gene:FBgn0039908 transcript:FBtr0332905	[more]

BLAST of Tau tubulin kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttbk2a	1.718e-99	60.67	tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-12...	[more]
ttbk2a	5.060e-99	60.67	tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-12...	[more]
ttbk2a	5.060e-99	60.67	tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-12...	[more]
ttbk2b	6.937e-99	59.00	tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ttbk1a	1.897e-97	59.67	tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-10...	[more]

BLAST of Tau tubulin kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
col24a1	8.874e-101	61.67	collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X...	[more]
col24a1	3.723e-98	61.33	collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X...	[more]
col24a1	7.507e-98	61.33	collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X...	[more]
col24a1	2.892e-95	62.64	collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X...	[more]
col24a1	7.024e-86	54.33	collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X...	[more]

BLAST of Tau tubulin kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ttbk2	3.340e-101	61.00	tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:21...	[more]
Ttbk1	4.915e-99	59.33	tau tubulin kinase 1 [Source:MGI Symbol;Acc:MGI:21...	[more]
Ttbk2	8.830e-99	61.00	tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:21...	[more]
Ttbk2	8.830e-99	61.00	tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:21...	[more]
Ttbk2	2.602e-98	61.00	tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:21...	[more]

BLAST of Tau tubulin kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q3UVR3\|TTBK2_MOUSE	6.177e-98	61.00	Tau-tubulin kinase 2 OS=Mus musculus OX=10090 GN=T...	[more]
sp\|Q6IQ55\|TTBK2_HUMAN	7.478e-97	61.00	Tau-tubulin kinase 2 OS=Homo sapiens OX=9606 GN=TT...	[more]
sp\|Q6PCN3\|TTBK1_MOUSE	4.677e-95	59.00	Tau-tubulin kinase 1 OS=Mus musculus OX=10090 GN=T...	[more]
sp\|Q5TCY1\|TTBK1_HUMAN	5.304e-95	59.00	Tau-tubulin kinase 1 OS=Homo sapiens OX=9606 GN=TT...	[more]
sp\|Q8IMC6\|ASATR_DROME	1.114e-94	61.99	Tau-tubulin kinase homolog Asator OS=Drosophila me...	[more]

BLAST of Tau tubulin kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1A7WKG4	1.229e-104	61.33	Tau tubulin kinase 2 OS=Iconisemion striatum OX=60...	[more]
A0A1A8N2T4	3.926e-104	60.00	Tau tubulin kinase 2 (Fragment) OS=Nothobranchius ...	[more]
V3ZM49	1.875e-103	61.56	Protein kinase domain-containing protein OS=Lottia...	[more]
R7V2U7	4.092e-103	61.99	Protein kinase domain-containing protein OS=Capite...	[more]
A0A267DEE2	4.282e-103	61.33	Protein kinase domain-containing protein OS=Macros...	[more]

BLAST of Tau tubulin kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttbk1a	3.372e-102	52.57	tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-10...	[more]
ttbk1b	3.367e-100	47.07	tau tubulin kinase 1b [Source:ZFIN;Acc:ZDB-GENE-10...	[more]
ttbk2b	1.912e-97	58.00	tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ttbk2b	1.585e-87	54.00	tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
csnk1g1	2.611e-32	31.80	casein kinase 1 gamma 1 [Source:NCBI gene;Acc:1030...	[more]

BLAST of Tau tubulin kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000004926.1	4.443e-80	57.33	pep scaffold:Pmarinus_7.0:GL480178:196:11423:1 gen...	[more]
csnk1g2a	1.863e-34	32.06	casein kinase 1, gamma 2a [Source:ZFIN;Acc:ZDB-GEN...	[more]
ENSPMAT00000008477.1	3.490e-28	32.57	pep scaffold:Pmarinus_7.0:GL482342:316:9736:-1 gen...	[more]
csnk1g1	2.271e-21	32.28	casein kinase 1, gamma 1 [Source:NCBI gene;Acc:494...	[more]
ENSPMAT00000001691.1	5.102e-16	34.91	pep scaffold:Pmarinus_7.0:GL476581:539457:546336:1...	[more]

BLAST of Tau tubulin kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
HRR25	9.844e-27	31.25	Conserved casein kinase; regulates diverse events ...	[more]
YCK1	1.163e-26	30.51	Palmitoylated plasma membrane-bound casein kinase ...	[more]
YCK2	2.775e-26	30.69	Palmitoylated plasma membrane-bound casein kinase ...	[more]
YCK3	3.855e-24	28.27	Palmitoylated vacuolar membrane-localized casein k...	[more]
MPS1	7.232e-9	22.91	Dual-specificity kinase; autophosphorylation requi...	[more]

BLAST of Tau tubulin kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46789	2.211e-100	60.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34289	1.040e-32	33.21	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34742	3.011e-30	33.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46523	3.599e-27	30.51	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48738	9.926e-24	29.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Tau tubulin kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttbk2a	2.419e-92	59.60	tau tubulin kinase 2 [Source:NCBI gene;Acc:1011741...	[more]
ttbk1a	5.886e-89	55.59	tau tubulin kinase 1 [Source:NCBI gene;Acc:1053541...	[more]
ttbk2b	3.380e-87	54.00	tau-tubulin kinase 2 [Source:NCBI gene;Acc:1011577...	[more]
ttbk2a	7.705e-85	53.33	tau tubulin kinase 2 [Source:NCBI gene;Acc:1011741...	[more]
csnk1g1	3.654e-32	31.15	casein kinase 1 gamma 1 [Source:NCBI gene;Acc:1011...	[more]

BLAST of Tau tubulin kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000026133.1	0.000e+0	100.00	SMESG000026133.1	[more]
SMESG000030545.1	2.251e-111	65.00	SMESG000030545.1	[more]
SMESG000048011.1	5.519e-110	62.33	SMESG000048011.1	[more]
SMESG000030545.1	1.282e-109	65.00	SMESG000030545.1	[more]
SMESG000068893.1	1.784e-101	61.74	SMESG000068893.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30023193 ID=SMED30023193|Name=Tau tubulin kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=4469bp
ATTTTTTAAAGTATTAACAACCAATGTATTTCGATCAACAAAAGATTTAT
TAGAGAATTTATTATTTATTATGTGTTTTTAACAGATTAAAATCAGTTTT
TAAATTATTTTAAAAATAGAAATGTTTAATGACTTCTTCAACTCAAGAAC
CTGATTTAGCATCTGAAGGAGACGTTATCAAAGAGCGATGGAAGATCATC
AAAAAACTTGGTGGGGGTGGTTTTGGAGAAATCTATGAATGTGTTGATCC
AATAGTCAAAGATAAGGTGGCCATTAAATTAGAATCATCTAAACTACCGA
AACAAGTGTTGAGAATGGAGGTTTCAGTGTTAAAAAAGTTACAAGGGACC
AAACATGCATGTAAATGTTATGGTTATGGACGTAATGATAAATTCAGTTA
CGTCGCAATGACACTTCAGGGTAAAAATCTTGCTGATCTCAGGCGACAAA
TGAAGTCTGGTTCTTTCTCTATTTCGACAACTCTACAGTTGACACTACAA
ATTTTGGATTCAATTGAAAATATTCATAGCATTGGTTTTCTCCATCGTGA
CATTAAACCGTCAAATTTTGCAATTGGAGGCTCAGCAGAAACCAGACGAA
TAGTCTATATGTTAGATTTTGGCCTTGCCCGCCAATTTGTTCTACCCGAC
GGTAGCTTCCAAGTTCGTCCACCAAGAGATGTCGCTGGTTTTCGTGGAAC
AGTTAGATATGCATCGATGAATGCTCACAACAACGTTGAAATGGGTCGTC
ATGATGATTTGTGGTCAGCATTTTATATGTTTTATGAAATGATTACTGGT
CAGTTGCCATGGCGTCGAATGAAAGACAAGGAACAGGTCGGCCAAATCAA
ATTGAACTACGATCACACTAAATTTCTTCAATCATTACCGAATGAATTCA
AGCCATTTCTAGCACATATTCAAGAACTTGATTATTTTAAGAAACCCGAT
TATGAAATGATGAAAAATCTCATTCGAGATTGTATGAAATCGAAAAAGGT
TACACAATCTGATTCTTTTGATTGGGAACTCAACTCGGTATCCACAACCC
CAGTGACAGTATCATCCAATATAGATACTAATATGGAGAGACGTAATTCT
GCTATTATTTCGACTGGAACTGGTCCACAAATACATGTTGCTAAAAGTTC
CCGGCAAAACAATGGTGACGTTCAAAATCATGTGGCCATTGAAGAATTTC
GAAATAAACCATCAAAGACCGTCAAAGAATCTGTATTAAAGGCGAAAAAG
TCCCATTTGGATATGCCTGATAATGGGGACAACGGAGTATCTGTCGGTAA
AAGCAGTTATCGACACGCAGTGTCAAATATTGCTGGAAAATCTGAAAAAA
GTCAAAATGCTCGCAATACTATGCCTCCGATATCTCCTCGGTCTACTTTC
GCCAATCAAAAAGAAAAGATGTTTGATATAAAATTTTCCGAAGAAATCGA
AACACCAAGAAATGCGGTCCAATCAGAAATTACCTCCCATGAAAAGCACT
CTTCTGTAATTGATAGTCACAACAGATCGGCCAGTCGAAGAAATCGTCGT
GAACCGGAACTGGTAAATAAACCCAGTAGATTACCGGTTCTTATGAAAAC
AAGTTCAAGTGATTCTAATAACAAATCTAATGAATATGAACCCGATCAGC
CGTTTTTTCAAAATCATAAAACCACCGAAGATTCCGTATTGTTTGCAGAT
AACTATGAAACAAATTTTGAATCAGAAAATCAAAAACATCGCGGAATTTC
AGCAGCACTGGCTGTGGTACCAAATTCGATGAAAGTAACTGGGAATTTGC
CTCCGAAACCAGCAACCTCTTCAACTCCGTCAAATCTCGTGAAAAACACC
GAAAAACTAAATAAAAATTCCATCAATCTTCGGGGAAACTTTCTTCAGAG
TGTTGGTGGCAGTGTGGCGACTCATGCAGTGAACGATGATCAATTCGATG
TCAGTAACGCGCCTGACGCTACGAAAGCAGTACTTTTAAGTAATCAAGAA
TGTGATGATGATGACGAAGACAATTGCAATTTATCCGATCATTTTGAAGA
CGATAAATATCACGTAAATCAGTTCAAACAACAAGAGTCTGATACAAAGG
AAAATACCGCAACGAAAGATAGCAAATTAAACGGTCAAATCAAACCCCAA
TCCTACATAAGCAGTGGAGATAATTTATCTACTACTAATCACAATGATTC
TTCCAAACGATCTCGTCGACAACCGATGATAGTCACTGAAAAGTCTTCAG
CAAAAATTCAAGCTCAACTCGCTGATAAATCTCGAGCGTCAAGTTCGATT
TTGAGTCGGTTAAACAATCAAGAAGAAGACAGTTCGAATTGCAAGAGTAA
AGAATCCCATGAAATGGAAATGACTTTGTCCAAAGCAAAAACGACGACGA
CATCGGGCTATATTTCATCGGTATCAAAATACGACGTGAACCAGAAACCG
AGTTATGAGGCTATCGGTCAAAGTGGGGACGATAAAAACCACAACTACCT
CAGTCAGCGGCATCCCTATTATGGAGTGGTCGATTCTACGAGTTGCAGTG
CTTCGGCTAACGTTTTAAGTCATAAACACAACAATGAAATGCAAAAGTCC
AATTCCAATATCTCTCGATTACCTCCGAAAAGCTCCGAACAACGTTACAA
AGTCAATAAATACTCCACCAATCAAGACACTTCAGATTTATCTATATCGA
GATCTAGTCGTCGTAACGGTGCTTCGAAATCTAATCATCAAAATTCGAGC
TCTAATCCTAAATCCGGATTCCACATATCGAGTAAAGATTCAGCCAACAA
ACACAATTACTATGACCTCAAACGATCATCTAATCTTCAATTCAGTAATC
ATCACACATTTCAGAACCTTAATCACTCGGATCATGGGGTGATTGTTTCA
CAGGGAACCTATAACAGCTCAAATCATCACAATTCTCGACGAGATCCCAG
CAATTTTAACAATCACCAATCTGACCTGAAATTGGGAATGAAAGATCACT
CTTCGTCATCAAGGACATTCGATTCATATCGCGACAGTGATAGACCAACT
CCGAAACCTCGTTCGCATCATCGATCTCAAAGTCACACAAATCGTGAAGT
CGCCAACAGTATCATCAATGGCCACGGTGATAGCACAATAATTCGTCAGA
AAAATAACTATTACACTTCCTCCATCAACAACATGAACAATAATCTATCA
CCAAATGACATGAATGACCATTCTTTCGACAGATATAATCTCAGGCCCCG
CAGTTCCAGTCGAGAGTCGATCAGTAAATATAGCAACAACAAAAAACCCA
ATCCTACGTCATCTGGAAGCCAAAAGCCTGTTGTCTGCAAACACAACTCG
TCTCCATCGCGACGTCGAAGCACCAGTTTCAATAATAACAACGATTGCGT
GCAATGTCAAAATTACGGGGTGAAAAAGTGTACTACTCATTACAGCCAGA
AAAACAACAGCAATCTTGTTCTCAACACGAATTCCAGTGGAGTTTTAGTG
GCAAACTCTCTCACCAGAAGCGGAAGCATTGTCATGAAAAGCAAATCGGA
TTTGAACCTTTCAATGGCCGGTCTGATTCAAAATCGCCATTCGGGAAAAG
GACAACGCAGTAGTCATGGAAAAGCCCAGCATTCCTCTCAGTCTCCGTCG
GTAGTTTCCCAGTATTCCACGGCGAAAAATTACTCGACTTCACCAAACCA
CCGAACAGACTCGTCTATTCATCGCTCGTTGACTTCATCAATTAATCGCA
GCAGCAGTGCCGATCTCCTCAACCATTATTTGAGACATTCAAAAACCTTA
TCGAACAGTAACATGCAAAATAAATCGTCCAAACCCCATCAGCACGTCCA
ATCGTCGTCGAATTCCATTCTGAAACCGAAACCGAAACCGAATCCTCACG
GTCAATACAACAACATGTCGACTTCCACATCCGTTACGTCGGGAATCCAC
CGGCACGTGTATAAAAAAGTAATACGTGAAGACTCCGTCGACAGTGATAT
CTCAGTGAGTCACATTACGACTTCAACGACAAATCAAGCCAATTCCTCTT
TCAATCCCAAACCGCCTTCGTCGGGGAAATATCACCAGACTCACGTGTTT
CGGAACCGGCAATATACGTCCACGAAAATCATCAACTAGATCGAAATGCC
CATTATTATATACTGCATTATATACACCGGCCTTATCATATTCTATATAC
CAACAGAGTTTTTGTTGCTTTTTTTTATTTGATATTTTTTCATCGTCTTA
TTACTTTGATTTTCGGACAAATTTTTACATTATATAATAATAATAATTAT
AATTATTGAAATTTCATAACAACCCAATGAAAAAATTCAGTAATTTGCTC
AAAAAATTTATTAATTTTATTATCAGATTATTCTATGTCTCTCTCTCCCT
CTCTCTCTCTTTATGTCTATATTTATACATACGAAAAACAATTCAACATA
GATTTAAGCAATAAAACTA

protein sequence of SMED30023193-orf-1

>SMED30023193-orf-1 ID=SMED30023193-orf-1|Name=SMED30023193-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1337bp
MTSSTQEPDLASEGDVIKERWKIIKKLGGGGFGEIYECVDPIVKDKVAIK
LESSKLPKQVLRMEVSVLKKLQGTKHACKCYGYGRNDKFSYVAMTLQGKN
LADLRRQMKSGSFSISTTLQLTLQILDSIENIHSIGFLHRDIKPSNFAIG
GSAETRRIVYMLDFGLARQFVLPDGSFQVRPPRDVAGFRGTVRYASMNAH
NNVEMGRHDDLWSAFYMFYEMITGQLPWRRMKDKEQVGQIKLNYDHTKFL
QSLPNEFKPFLAHIQELDYFKKPDYEMMKNLIRDCMKSKKVTQSDSFDWE
LNSVSTTPVTVSSNIDTNMERRNSAIISTGTGPQIHVAKSSRQNNGDVQN
HVAIEEFRNKPSKTVKESVLKAKKSHLDMPDNGDNGVSVGKSSYRHAVSN
IAGKSEKSQNARNTMPPISPRSTFANQKEKMFDIKFSEEIETPRNAVQSE
ITSHEKHSSVIDSHNRSASRRNRREPELVNKPSRLPVLMKTSSSDSNNKS
NEYEPDQPFFQNHKTTEDSVLFADNYETNFESENQKHRGISAALAVVPNS
MKVTGNLPPKPATSSTPSNLVKNTEKLNKNSINLRGNFLQSVGGSVATHA
VNDDQFDVSNAPDATKAVLLSNQECDDDDEDNCNLSDHFEDDKYHVNQFK
QQESDTKENTATKDSKLNGQIKPQSYISSGDNLSTTNHNDSSKRSRRQPM
IVTEKSSAKIQAQLADKSRASSSILSRLNNQEEDSSNCKSKESHEMEMTL
SKAKTTTTSGYISSVSKYDVNQKPSYEAIGQSGDDKNHNYLSQRHPYYGV
VDSTSCSASANVLSHKHNNEMQKSNSNISRLPPKSSEQRYKVNKYSTNQD
TSDLSISRSSRRNGASKSNHQNSSSNPKSGFHISSKDSANKHNYYDLKRS
SNLQFSNHHTFQNLNHSDHGVIVSQGTYNSSNHHNSRRDPSNFNNHQSDL
KLGMKDHSSSSRTFDSYRDSDRPTPKPRSHHRSQSHTNREVANSIINGHG
DSTIIRQKNNYYTSSINNMNNNLSPNDMNDHSFDRYNLRPRSSSRESISK
YSNNKKPNPTSSGSQKPVVCKHNSSPSRRRSTSFNNNNDCVQCQNYGVKK
CTTHYSQKNNSNLVLNTNSSGVLVANSLTRSGSIVMKSKSDLNLSMAGLI
QNRHSGKGQRSSHGKAQHSSQSPSVVSQYSTAKNYSTSPNHRTDSSIHRS
LTSSINRSSSADLLNHYLRHSKTLSNSNMQNKSSKPHQHVQSSSNSILKP
KPKPNPHGQYNNMSTSTSVTSGIHRHVYKKVIREDSVDSDISVSHITTST
TNQANSSFNPKPPSSGKYHQTHVFRNRQYTSTKIIN*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000054	dorsal region of the epidermis
PLANA:0000096	ventral epidermis
PLANA:0000099	neuron
PLANA:0000106	ciliated epithelial cell
PLANA:0000418	head
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR009081	PP-bd_ACP
IPR000719	Prot_kinase_dom
IPR017441	Protein_kinase_ATP_BS
IPR011009	Kinase-like_dom_sf

Vocabulary: **biological process**
Term	Definition
GO:0006468	protein phosphorylation
GO:0007224	smoothened signaling pathway
GO:0008360	regulation of cell shape
GO:0008589	regulation of smoothened signaling pathway
GO:0016310	phosphorylation
GO:0018105	peptidyl-serine phosphorylation
GO:0021915	neural tube development
GO:0030030	cell projection organization
GO:0030900	forebrain development
GO:0042733	embryonic digit morphogenesis
GO:0060271	cilium morphogenesis
GO:1902857	positive regulation of non-motile cilium assembly
GO:1903828	negative regulation of cellular protein localization
GO:1990403	embryonic brain development

Vocabulary: **molecular function**
Term	Definition
GO:0005524	ATP binding
GO:0004672	protein kinase activity
GO:0000166	nucleotide binding
GO:0004674	protein serine/threonine kinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity

Vocabulary: **cellular component**
Term	Definition
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005814	centriole
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005929	cilium
GO:0035869	ciliary transition zone
GO:0036064	ciliary basal body
GO:0042995	cell projection
GO:0045111	intermediate filament cytoskeleton

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000719	Protein kinase domain	SMART	SM00220	serkin_6	coord: 21..297 e-value: 1.1E-18 score: 78.1
IPR000719	Protein kinase domain	PFAM	PF00069	Pkinase	coord: 22..276 e-value: 9.9E-31 score: 107.1
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 21..282 score: 27.072
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 3..345 e-value: 6.5E-91 score: 307.3
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 449..513
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 734..749
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 400..427
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1040..1083
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1298..1319
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 952..990
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1227..1269
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 701..733
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 400..426
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1227..1250
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1153..1203
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 650..758
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 952..978
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 486..513
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 815..881
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1042..1083
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 455..480
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 663..689
None	No IPR available	PANTHER	PTHR11909	CASEIN KINASE-RELATED	coord: 5..302
None	No IPR available	PANTHER	PTHR11909:SF201	TAU-TUBULIN KINASE 2	coord: 5..302
None	No IPR available	CDD	cd14017	STKc_TTBK	coord: 20..281 e-value: 1.19026E-138 score: 421.666
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 27..50
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 15..300