Frizzled-4

Query:  130 ENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMH-PSQEE-NLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHM-RNGEKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNS 1644
            + E+ +  PI I  CQN  YN T +      + + + ++ + T+  L+  GCS  L F LCSVYVP C     I + PC  +C  V+  CEP+LK    +WPE LNCS+FP ++ H   CM  P  EE  L  K  IQ             P +   +C  +  N ++Y+++ R+  C LKC  +   +S+ +K   +IWM V  SL F+ST FT +TF   + R  YPE+PIIFL+  YNIYSI+ ++RL +GRE++SCDF+  + + +LIQEGL+NT CAI FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +V T+ +LI+R VDADEL GLC VG Q  D L  F + P    L+IG +F+ +G     ++ +    K      K+  L+    ++G+FS++Y +    +I C  Y+  N+     A  ++S   D+ +AV +LK FM+ +VGI S +WI S  ++  W+KC   L+      ++ + N 
Sbjct:   39 DEEERRCDPIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQ-------------PGE---ECHSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAA-EPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSVLYTVPATCVIACYFYEISNW-----ALFRYSA-DDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNG 525          

Query:  109 ISIVDSIENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMH--------PSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSE--NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKF-------SKRKDAIVA-------VFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            IS +D       K +PI I  C++  YN T +      + + E  I +  +  L+  GC  HL F LCS+Y P C       +  CR +CE+ +  C PI++  N  WP+ L+C + P ++     CM         P++   L   +       +   + + +    RG C    N  K+  + ++  CA  C+   + ++S+E K  A +W+ +   L F S+ FT +TF  +  R RYPE+PIIFL+  Y +YS+  L+RLF G E ++CD D  SGQ  +IQEGLE+T C + FL+ ++F  A+ +WW++L L W L         ++  NS  FHL  W + +V T+ +L++R V  DEL G+C VG    + L  F +IP    L+IG  F+LSGF    +  ++       +  K+  L+    R+GLFS++Y +    +I C  Y+  N  YW     +        +K  D ++A       +F++K FM  VVGI S +WI +  ++ +W++
Sbjct:   21 ISSMDMERPGDGKCQPIEIPMCKDIGYNMTRMPNLMGHENQREAAIQLHEFAPLVEYGCHGHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSPIMEQFNFKWPDSLDCRKLPNKNDPNYLCMEAPNNGSDEPTRGSGLFPPLFRPQRPHSAQEHPLKDGGPGRGGCD---NPGKFHHVEKSASCAPLCTPGVDVYWSREDKRFAVVWLAIWAVLCFFSSAFTVLTFLIDPARFRYPERPIIFLSMCYCVYSVGYLIRLFAGAESIACDRD--SGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLIPLACYLVIGTSFILSGFVAL-FHIRRVMKTGGENTDKLEKLM---VRIGLFSVLYTVPATCVIACYFYERLNMDYWKILAAQHKCKMNNQTKTLDCLMAASIPAVEIFMVKIFMLLVVGITSGMWIWTSKTLQSWQQ 533          

Query:  103 LLISIVDSIENEKCKP-KPIAIGQCQNKFYNFTS----LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSL-------NKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSEND--FFSKESKTIAEIWMKVITSLTFVSTLFTCVTFC-HNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWS--------RAPIKFSKRKD--------AIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQ 1668
            L I   D        P + + I  C+   YN T     L    + E    +  +  L+  GC  HL F LCS+Y P C       +  CR +CE+ +  C PI++  N  WP+ L+C+R P  +     CM   +          + L +        +   ++       G C    N EK+ ++ ++  CA +C      F+S+  K  A +WM V ++L F ST FT +TF     R +YPE+PIIFL+  YN+YS++ L+R   G + V+CD +  +G   +IQEGLENT C + FLL ++F  A+ +WW++L L W L         ++  +   FH+  W + ++ T+ +L LR V  DEL GLC V       L  F ++P    L++G  FLL+GF    +  +K       + +K+  L+    ++G+FSI+Y +    +I C +Y+  N  +W          A      R+D          VAVF+LK FM+ VVGI S +W+ S  +   W+    +   K+   +      R   SYG+
Sbjct:   23 LEIGRFDPERGRGAAPCQAVEIPMCRGIGYNLTRMPNLLGHTSQGEAAAELAEFAPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPAEPHKGLGMLPVAPRPARPPGDLGPGAGGSGTCE---NPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVLTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQE--AGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVILTLRKVAGDELTGLCYVASTDAAALTGFVLVPLSGYLVLGSSFLLTGFVAL-FHIRKIMKTGGTNTEKLEKLM---VKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCAAAAGPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQS---LCYRKIAAGRARAKACRAPGSYGR 563          

Query:  157 IAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFP-LESSHQMQCMHPSQEENL--------QRKIQIQNLSLNKDRNNIHEPKQYRGQCRH-----MRNGEKYVFINRTGR---CALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA-----PIKFSKRKDAIVA--VFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            I +  C+   YN T +    + D + E  + +  +  L+   CS  L F LCS+Y P C  D    L PCR VCE+ +  C P+++    +WPE+++C R P L    ++ CM  ++ E           +                     +  +CR      ++         RTG+   CA+ C +  F S + +T A  W+ + + L F+ST  T  TF  +  R RYPE+PIIFL+  Y   S+  L+RL +G   V+C  +       +  E      C I FLL +FF  A+ +WW++L L W L   +     ++A  +  FHL  WL+ SV +++ L L SVD D + G+C VG Q  + L  F + P ++ L++G +FLL+GF    +R +    +      K+  L+    R+G+F+++Y +  + ++ C LY+ +    W  A     P   + +  A     V +LK+FM  VVGI S +WI S  +V +W++
Sbjct:   36 ITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGRDAEVLCMDYNRSEATTAPPRPFPAKPTLPGPPGAPASGGECPAGGPFVCKCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSF-SADERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSRE----HNHIHYETTGPALCTIVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSL-FRIRSVIKQGGTKTDKLEKLM---IRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGHDTGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESWRR 532          

Query:  151 KPIAIGQCQNKFYNFTS----LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKI---------QIQNLSLNKDRNNIHEPKQYRG-----QCRHMRNGEKYVFINRTGR--CALKCSE-----NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA-------------PIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVML 1602
            +PI+I  C +  YN T     L    + +  + +  +  L+   CS  L F LCS+Y P C       + PCR +CE+ +  CE ++      WPE+L C  FP   + Q+ C+  +  E+    +         Q               P +Y        C  +     Y+     G   CA  C       + FFS+E    A +W+   + L   ST FT  T+  + +R RYPE+PIIFL+  Y + S++ +    L +E+V C+          + +G +   C I F++ +FFS A+ +WW++L L W L   +     ++  NS  FHL  W + +V T+++L +  +D D L G+C VG  + D L  F + P  + L IG  FLL+GF    +R +          +K+  L+    R+G+FS++Y +    +I C  Y+     +W R+             P  ++ R      V+++K+ M  +VGI S  WI S  ++ +W+K +  L
Sbjct:   40 QPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQ-AIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQI-CVGQNHSEDGAPALLTTAPPPGLQPGAGGTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSQEETRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVL-QERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSL-FRIRTIMKHDGTKTEKLERLM---VRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRL 555          

Query:  112 SIVDSIENEKCKPKPIAIGQCQNKFYNFT----SLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNR-RIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAI-------VAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK-CFVMLLEKVTFNKKIKSNSREI 1653
            SI D     KC P  I I  C++  YN+T    ++  + +  +Q   E ++ L+   C  H++F +CSV+ P C       +  C+ VCE+V+ DC  IL+   + WPE LNC++FP        CM P+++E +        L      ++  +P    G    + + + +   +    CA  C  N  FS ++K +   W     +      LF+ +TF  +R R R+PE+ + +L+    I S+  L  LF+     SC     +G+  L     +N+ C  +FLLN+FFSTA  +WW+M      L          +   S   H   W ++S+ T+ VLI   VDA EL  LCSVG      LL F I+P+ IC++IG  F++ GF         F  +     +    ++ +GF   LF    I+     + C+ Y++     W+R  I   ++  A          +++     +   G +  +W+LS  +V AWK   F  +         I+ ++R +
Sbjct:   18 SIFDQAVKGKCIP--IDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFP---DPPELCMKPTEDE-ITGGFSAPRLPTKGSSSSSSKPT---GCPSDLVDVDPH---DPKSHCAFACQSNVMFSTDNKRMVRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCH-ALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRGTDTSKLEKLMVKMGFFCALF----ILPNVIELVCQCYKFMILTQWTRMTIDCKQQSGACHRPTPPQAEIYMTAVISSLATGFSCLMWVLSAKTVHAWKNFIFCGMCSSAPVKNPIEPSTRPL 527          

Query:  112 SIVDSIENEKCKPKPIAIGQCQNKFYNFT----SLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNR-RIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAI-------VAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK-CFVMLLEKVTFNKKIKSNSREI 1653
            SI D     KC P  I I  C++  YN+T    ++  + +  +Q   E ++ L+   C  H++F +CSV+ P C       +  C+ VCE+V+ DC  IL+   + WPE LNC++FP        CM P+++E +        L      ++  +P    G    + + + +   +    CA  C  N  FS ++K +   W     +      LF+ +TF  +R R R+PE+ + +L+    I S+  L  LF+     SC     +G+  L     +N+ C  +FLLN+FFSTA  +WW+M      L          +   S   H   W ++S+ T+ VLI   VDA EL  LCSVG      LL F I+P+ IC++IG  F++ GF         F  +     +    ++ +GF   LF    I+     + C+ Y++     W+R  I   ++  A          +++     +   G +  +W+LS  +V AWK   F  +         I+ ++R +
Sbjct:   18 SIFDQAVKGKCIP--IDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFP---DPPELCMKPTEDE-ITGGFSAPRLPTKGSSSSSSKPT---GCPSDLVDVDPH---DPKSHCAFACQSNVMFSTDNKRMVRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCH-ALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRGTDTSKLEKLMVKMGFFCALF----ILPNVIELVCQCYKFMILTQWTRMTIDCKQQSGACHRPTPPQAEIYMTAVISSLATGFSCLMWVLSAKTVHAWKNFIFCGMCSSAPVKNPIEPSTRPL 527          

Query:  112 SIVDSIENEKCKPKPIAIGQCQNKFYNFT----SLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNR-RIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAI-------VAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK-CFVMLLEKVTFNKKIKSNSREI 1653
            SI D     KC P  I I  C++  YN+T    ++  + +  +Q   E ++ L+   C  H++F +CSV+ P C       +  C+ VCE+V+ DC  IL+   + WPE LNC++FP        CM P+++E +        L      ++  +P    G    + + + +   +    CA  C  N  FS ++K +   W     +      LF+ +TF  +R R R+PE+ + +L+    I S+  L  LF+     SC     +G+  L     +N+ C  +FLLN+FFSTA  +WW+M      L          +   S   H   W ++S+ T+ VLI   VDA EL  LCSVG      LL F I+P+ IC++IG  F++ GF         F  +     +    ++ +GF   LF    I+     + C+ Y++     W+R  I   ++  A          +++     +   G +  +W+LS  +V AWK   F  +         I+ ++R +
Sbjct:   18 SIFDQAVKGKCIP--IDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFP---DPPELCMKPTEDE-ITGGFSAPRLPTKGSSSSSSKPT---GCPSDLVDVDPH---DPKSHCAFACQSNVMFSTDNKRMVRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCH-ALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRGTDTSKLEKLMVKMGFFCALF----ILPNVIELVCQCYKFMILTQWTRMTIDCKQQSGACHRPTPPQAEIYMTAVISSLATGFSCLMWVLSAKTVHAWKNFIFCGMCSSAPVKNPIEPSTRPL 527          

Query:  112 SIVDSIENEKCKPKPIAIGQCQNKFYNFT----SLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNR-RIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAI-------VAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            SI D     KC P  I I  C++  YN+T    ++  + +  +Q   E ++ L+   C  H++F +CSV+ P C       +  C+ VCE+V+ DC  IL+   + WPE LNC++FP        CM P+++E +        L      ++  +P    G    + + + +   +    CA  C  N  FS ++K +   W     +      LF+ +TF  +R R R+PE+ + +L+    I S+  L  LF+     SC     +G+  L     +N+ C  +FLLN+FFSTA  +WW+M      L          +   S   H   W ++S+ T+ VLI   VDA EL  LCSVG      LL F I+P+ IC++IG  F++ GF         F  +     +    ++ +GF   LF    I+     + C+ Y++     W+R  I   ++  A          +++     +   G +  +W+LS  +V AWK
Sbjct:   18 SIFDQAVKGKCIP--IDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFP---DPPELCMKPTEDE-ITGGFSAPRLPTKGSSSSSSKPT---GCPSDLVDVDPH---DPKSHCAFACQSNVMFSTDNKRMVRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCH-ALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRGTDTSKLEKLMVKMGFFCALF----ILPNVIELVCQCYKFMILTQWTRMTIDCKQQSGACHRPTPPQAEIYMTAVISSLATGFSCLMWVLSAKTVHAWK 503          

Query:  112 SIVDSIENEKCKPKPIAIGQCQNKFYNFT----SLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNR-RIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAI-------VAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            SI D     KC P  I I  C++  YN+T    ++  + +  +Q   E ++ L+   C  H++F +CSV+ P C       +  C+ VCE+V+ DC  IL+   + WPE LNC++FP        CM P+++E +        L      ++  +P    G    + + + +   +    CA  C  N  FS ++K +   W     +      LF+ +TF  +R R R+PE+ + +L+    I S+  L  LF+     SC     +G+  L     +N+ C  +FLLN+FFSTA  +WW+M      L          +   S   H   W ++S+ T+ VLI   VDA EL  LCSVG      LL F I+P+ IC++IG  F++ GF         F  +     +    ++ +GF   LF    I+     + C+ Y++     W+R  I   ++  A          +++     +   G +  +W+LS  +V AWK
Sbjct:   18 SIFDQAVKGKCIP--IDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFP---DPPELCMKPTEDE-ITGGFSAPRLPTKGSSSSSSKPT---GCPSDLVDVDPH---DPKSHCAFACQSNVMFSTDNKRMVRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCH-ALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRGTDTSKLEKLMVKMGFFCALF----ILPNVIELVCQCYKFMILTQWTRMTIDCKQQSGACHRPTPPQAEIYMTAVISSLATGFSCLMWVLSAKTVHAWK 503          

Query:  151 KPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKI----QIQNLSLNKDRNNIHEP------------KQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSC--DFDP------VSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYW------------------SRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            +PI I  C+N  YN T +       ++ E  + +  +  L+  GCS  L   LCS+YVP C       + PCR +CE  +  CE ++K  N +WPE L CS+FP+     + C+  +   +          +  ++  K +  +  P            K   G    ++ G K +       C   C    FF +  +T+   W+    ++   S LFT +TF   + R RYPE+ I+FL   Y +   + +  L  G + VSC   F P      +     + Q   + T+C + F+  +F   A   WW  L   W L   L     ++   S +FHL  W + ++ T+SVL L  V+ D L G+C VG+     L  F I+P  I L IG +FLL+GF    +R +           K+  L+    R+G FS ++I+    ++ C  Y+YYN+  W                  +RAP   S     I  +F++K+  + +VG+ S++W+ S  ++ +W+
Sbjct:   54 EPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILER-PIPPCRSLCESARV-CEKLMKTYNFNWPENLECSKFPVHGGEDL-CVAENTTSSASTAATPTRSVAKVTTRKHQTGVESPHRNIGFVCPVQLKTPLGMGYELKVGGKDLH-----DCGAPCHAM-FFPERERTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAG-DSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISL-FRIRTVMKTDGKRTDKLERLM---LRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHRDICKPFSIPCPAARAP--GSPEARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWR 562          

Query:  151 KPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKI----QIQNLSLNKDRNNIHEP------------KQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSC--DFDP------VSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYW------------------SRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            +PI I  C+N  YN T +       ++ E  + +  +  L+  GCS  L   LCS+YVP C       + PCR +CE  +  CE ++K  N +WPE L CS+FP+     + C+  +   +          +  ++  K +  +  P            K   G    ++ G K +       C   C    FF +  +T+   W+    ++   S LFT +TF   + R RYPE+ I+FL   Y +   + +  L  G + VSC   F P      +     + Q   + T+C + F+  +F   A   WW  L   W L   L     ++   S +FHL  W + ++ T+SVL L  V+ D L G+C VG+     L  F I+P  I L IG +FLL+GF    +R +           K+  L+    R+G FS ++I+    ++ C  Y+YYN+  W                  +RAP   S     I  +F++K+  + +VG+ S++W+ S  ++ +W+
Sbjct:   54 EPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTI-LERPIPPCRSLCESARV-CEKLMKTYNFNWPENLECSKFPVHGGEDL-CVAENTTSSASTAATPTRSVAKVTTRKHQTGVESPHRNIGFVCPVQLKTPLGMGYELKVGGKDLH-----DCGAPCHAM-FFPERERTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAG-DSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISL-FRIRTVMKTDGKRTDKLERLM---LRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHRDICKPFSIPCPAARAP--GSPEARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWR 562          

Query:  157 IAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQ-LEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNL-SLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMK----VITSLTFVSTLFTCVTFCHNRRIRYPEQPIIF--LTFSYNIYSISILLRLFLGREKVSCDFDP-VSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCW-------------TLFCALNVSALSLAKNSGI----------FHLFV-WLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIP 1221
            I I  C+   YN TS+      + + +V+  ++T+  L+   CS  L   LC+ YVP C     +  + PCR +CE V+  C P+L+     WP  L+C +FP E++H+  CM    E  L +  Q Q+L  L           +    C  +     YV + R+GRCA  C  +  F+   K +AEIW+         L  V+T+  C+      R+   +   +   L + +N+ ++   +R  +GR   +C  DP    + +L  +GL N +CA  FL+ ++F  A   WW +LCL W              +    N       +NS            F  FV W + +  T +V++ R VDADEL G C VG Q+   L      P
Sbjct:   49 IRIEMCRKIGYNETSMPNLVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPKAPVHAIGPCRSLCESVRIRCHPVLQGFGFPWPPALDCDKFPRENNHETMCMEGPGE--LHQPQQEQDLYGLPGQGIPGGLGGKLPMDCSGLAKSHLYVRLPRSGRCAPLCEADILFTPAEKHLAEIWVSTWAYAALGLALVATV--CLLASDGSRLASAKWSRLLSPLIWCHNMVTLGWAVRFMVGRTGTACGTDPQAPNESLLTVDGLSNASCASVFLMRYYFGMAACAWWAVLCLGWHRDIRRHSPDSKGHVVIPSNFGGSPAKRNSAKTAQQDLTQNNFVCFVAWGLPAFQTSAVIVARFVDADELLGACFVGNQSDKALQILVATP 436          

Query:  157 IAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQ-LEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNL-SLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMK----VITSLTFVSTLFTCVTFCHNRRIRYPEQPIIF--LTFSYNIYSISILLRLFLGREKVSCDFDP-VSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCW-------------TLFCALNVSALSLAKNSGI----------FHLFV-WLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIP 1221
            I I  C+   YN TS+      + + +V+  ++T+  L+   CS  L   LC+ YVP C     +  + PCR +CE V+  C P+L+     WP  L+C +FP E++H+  CM    E  L +  Q Q+L  L           +    C  +     YV + R+GRCA  C  +  F+   K +AEIW+         L  V+T+  C+      R+   +   +   L + +N+ ++   +R  +GR   +C  DP    + +L  +GL N +CA  FL+ ++F  A   WW +LCL W              +    N       +NS            F  FV W + +  T +V++ R VDADEL G C VG Q+   L      P
Sbjct:   49 IRIEMCRKIGYNETSMPNLVGNEMQTDVEYTLQTFAPLIEYDCSSQLKLFLCAAYVPMCTPKAPVHAIGPCRSLCESVRIRCHPVLQGFGFPWPPALDCDKFPRENNHETMCMEGPGE--LHQPQQEQDLYGLPGQGIPGGLGGKLPMDCSGLAKSHLYVRLPRSGRCAPLCEADILFTPAEKHLAEIWVSTWAYAALGLALVATV--CLLASDGSRLASAKWSRLLSPLIWCHNMVTLGWAVRFMVGRTGTACGTDPQAPNESLLTVDGLSNASCASVFLMRYYFGMAACAWWAVLCLGWHRDIRRHSPDSKGHVVIPSNFGGSPAKRNSAKTAQQDLTQNNFVCFVAWGLPAFQTSAVIVARFVDADELLGACFVGNQSDKALQILVATP 436          

Query:  622 INRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFC-HNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTN-CAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQ-XXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA---PIKFSK--RKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLL 1605
            I     C + C +  FFS + K  A +W+ + + L F STL T  TF     R +YPE+PI+FL+  Y + ++  L R FL  E+++CD        +L++E     + C + FLL +FF  A+ +WW++L   W L   L     ++ K+S  FHL  WL+ +V +V+VL+L +VD D + G+C VG   PD L TF + P  +  +I     +      F+ R+       +    K   L  +  R+G+FS++Y +    +I C LY+   +  W +A   P    K   K  + +V +LK+FM   VGI S +WI S  ++ +W++ +  LL
Sbjct:  294 IAGVPNCGIPC-KGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACD-------GLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLL 621          

Query:  109 ISIVDSIENEKCKPKPIAIGQCQNKFYNFTSLSQDQEAEVQ----IPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCM-HPSQEE 498
            + ++    N +C+   I I  C+   YN TS   +   E Q    + +  +  L+   CS  L F LCS+Y P C  D    L  CR VCE+ +  C PI++  +  WPE++ C   PL       CM  PS  E
Sbjct:   53 VPVIPKDPNLRCEE--ITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTE 185          

Query:  130 ENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNG-EKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQLNST 1680
            + E+    PI I  CQ+  YN T +        +++ ++ + T+  L+  GCS  L F LCSVYVP C     I + PC  +C  V+  C P+L+     WPE LNCS FP  +     CM    +E+                + +        +C  +  G E+Y ++ R+G C+L+C  +   + +++K   ++WM V   L F+ST FT +TF   + R  YPE+PIIFL+   NIYS++ ++RL +GRE++SCD +  +   +L+QEGL+NT CAI FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +V T+ +LI+R VDAD+L G+C VG Q  D L  F + P    L+IG +F+ +G     ++ +    K      K+  L+    ++G+FS++Y +    +I C  Y+  N+  + +        +D+ +A  +L+ FM+ +VGI S +W+ S  ++  W++C   L+     N ++K  +      G+ N T
Sbjct:   23 DEEEMTCDPIRISMCQDLGYNVTKMPNLVGNVLQSDAELQLTTFTPLIQYGCSSQLKFFLCSVYVPMCTEKVPIPIGPCGSMCMSVKRKCLPVLQEFGFVWPELLNCSLFPPTNDQNHMCMEGPGDED-------------PPFHAVRPVAPQEEECIALGAGVEQYAWVKRSGSCSLQCGYDTGLYRRQAKVFTDVWMAVWAVLCFISTTFTVLTFLVDSSRFSYPERPIIFLSMCCNIYSVAFIVRLTVGRERISCDLEE-AAVPVLVQEGLKNTGCAIVFLLTYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADDLAGMCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSVLYTVPATCVIACYFYEISNWADFRQT------ARDSYMAAEMLRIFMSLLVGITSGMWVWSAKTLHTWQRCSHRLVHTGR-NNRVKRTANGWVKPGKGNET 521          

Query:  118 VDSIENEKCKP---KPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYR--GQCRHMRNGEKYVFINRTGRCALKCSE--NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIK-----FSKRKD---------AIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            + S + E+ +P   +PI I  CQ   YN T +      D + E  I +  +  L+  GC  HL F LCS+Y P C       +  CR +CE+ +  C PI++  N +WPE LNCS+ P  +     CM   + +      + + +     R         R  G      N EK+ ++ ++  CA +CS   + F+S++ K  A IWM V ++L FVST FT +TF  +  R +YPE+PIIFL+  YN+YS++ ++R   G E ++CD +  +G+  +IQEGLE+T C I FL+ ++F  A+ +WW++L L W L         ++  +S  FH+  W + ++ T+ +L +R V  DEL GLC VG      L  F ++P    L+IG  F+L+GF    +  +K       + +K+  L+    ++G++SI+Y +    +I C  Y+  N  YW    ++     F  R++           VAVF+LK FM+ VVGI S +W+ S  ++  W+
Sbjct:   25 IGSYDLERGRPAKCEPIVIPMCQGIGYNLTRMPNFMDHDNQREAAIKLNEFAPLVEYGCDVHLRFFLCSLYAPMCTDQVSTSIPACRPMCEQARQKCSPIMEKFNYAWPESLNCSKLPTRNDPNALCMEAPENDTKTETKKGEGMLPVPPRPRQPGAGNARSGGTMGVCENPEKFQYVEKSETCAPRCSSAVDVFWSRQDKDFAFIWMAVWSTLCFVSTAFTVLTFLLDPHRFQYPERPIIFLSMCYNVYSVAFIIRSVAGAENIACDRE--NGELYIIQEGLESTGCTIVFLILYYFGMASSIWWVILTLTWFLAAGKKWGHEAIESHSSYFHMAAWGIPALKTIVILTMRKVAGDELTGLCYVGSMDVGALTGFVLVPLSCYLVIGTSFILTGFVAL-FHIRKVMKTEGTNTEKLEKLM---VKIGIYSILYTVPATCVIICYFYERLNMDYWKFRGLQSKCTTFPGRRNEDCSLDSSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQ 533          

Query:  118 VDSIENEKCKP---KPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYR--GQCRHMRNGEKYVFINRTGRCALKCSE--NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIK-----FSKRKD---------AIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            + S + E+ +P   +PI I  CQ   YN T +      D + E  I +  +  L+  GC  HL F LCS+Y P C       +  CR +CE+ +  C PI++  N +WPE LNCS+ P  +     CM   + +      + + +     R         R  G      N EK+ ++ ++  CA +CS   + F+S++ K  A IWM V ++L FVST FT +TF  +  R +YPE+PIIFL+  YN+YS++ ++R   G E ++CD +  +G+  +IQEGLE+T C I FL+ ++F  A+ +WW++L L W L         ++  +S  FH+  W + ++ T+ +L +R V  DEL GLC VG      L  F ++P    L+IG  F+L+GF    +  +K       + +K+  L+    ++G++SI+Y +    +I C  Y+  N  YW    ++     F  R++           VAVF+LK FM+ VVGI S +W+ S  ++  W+
Sbjct:   25 IGSYDLERGRPAKCEPIVIPMCQGIGYNLTRMPNFMDHDNQREAAIKLNEFAPLVEYGCDVHLRFFLCSLYAPMCTDQVSTSIPACRPMCEQARQKCSPIMEKFNYAWPESLNCSKLPTRNDPNALCMEAPENDTKTETKKGEGMLPVPPRPRQPGAGNARSGGTMGVCENPEKFQYVEKSETCAPRCSSAVDVFWSRQDKDFAFIWMAVWSTLCFVSTAFTVLTFLLDPHRFQYPERPIIFLSMCYNVYSVAFIIRSVAGAENIACDRE--NGELYIIQEGLESTGCTIVFLILYYFGMASSIWWVILTLTWFLAAGKKWGHEAIESHSSYFHMAAWGIPALKTIVILTMRKVAGDELTGLCYVGSMDVGALTGFVLVPLSCYLVIGTSFILTGFVAL-FHIRKVMKTEGTNTEKLEKLM---VKIGIYSILYTVPATCVIICYFYERLNMDYWKFRGLQSKCTTFPGRRNEDCSLDSSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQ 533          

Query:  103 LLISIVDSIENEKCKPKPIAIGQCQNKFYNFTS----LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHM----RNGEKYVFINRTGRCALKCSE--NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWS-RAP----IKFSKRKD---------AIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNS 1644
            L I   D       K +PI I  CQ   YN T     L+ + + E  I +  +  L+  GC  HL F LCS+YVP C       +  CR +CE+ +  C PI++  + SWP+ L+CS+ P  +     C+   + +      + + +     R+   +P    G+   +     N EK+ +++++  CA +C+   + ++S++ K  A IWM V ++L FVST FT +TF  + +R +YPE+PIIFL+  YNIYS++ ++R   G E ++CD +  +G+  +I+EGLE+T C I FL+ ++F  A+ +WW++L L W L         ++  +S  FH+  W + +V T+ +L +R V  DEL GLC VG      L  F +IP    LI+G  F+L+GF    +  +K       + +K+  L+    ++G+FSI+Y +    +I C  Y+  N  YW  RA     + F  R+            VAVF+LK FM+ VVGI S +W+ S  ++  W+  +   L   T +K   S S
Sbjct:   21 LEIGAYDLEHGRPGKCEPITIPMCQGIGYNMTRMPNLLNYESQEEASIKLNEFAPLVKYGCDIHLQFFLCSLYVPMCAEQVSASIPACRPMCEQARQRCSPIMEQFSFSWPDSLDCSKLPTNNDPNALCIEAPENDTQPETKKGEGMLPVPPRS--RQPTTVSGRISSISQSCENPEKFQYVDKSESCAPRCTPTVDVYWSRQDKDFAFIWMVVWSTLCFVSTAFTVLTFLLDPQRFQYPERPIIFLSMCYNIYSVAFIIRSVAGAENIACDRE--NGELYIIREGLESTGCTIVFLILYYFGMASSIWWVILTLTWFLAAGRKWGHEAIEAHSSYFHMAAWGIPAVKTIVILTMRKVAGDELTGLCYVGSMDSSALTGFVLIPLSCYLIVGTSFILTGFVAL-FHIRKIMKTGGTNTEKLEKLM---VKIGVFSILYTVPATIVIICYFYERLNMEYWKFRALENKCVSFPGRRSDDCSLDSSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQGLYNRRLGVQTSHKPCSSVS 551          

Query:  103 LLISIVDSIENEKCKPKPIAIGQCQNKFYNFTS----LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHM----RNGEKYVFINRTGRCALKCSE--NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWS-RAP----IKFSKRKD---------AIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNS 1644
            L I   D       K +PI I  CQ   YN T     L+ + + E  I +  +  L+  GC  HL F LCS+YVP C       +  CR +CE+ +  C PI++  + SWP+ L+CS+ P  +     C+   + +      + + +     R+   +P    G+   +     N EK+ +++++  CA +C+   + ++S++ K  A IWM V ++L FVST FT +TF  + +R +YPE+PIIFL+  YNIYS++ ++R   G E ++CD +  +G+  +I+EGLE+T C I FL+ ++F  A+ +WW++L L W L         ++  +S  FH+  W + +V T+ +L +R V  DEL GLC VG      L  F +IP    LI+G  F+L+GF    +  +K       + +K+  L+    ++G+FSI+Y +    +I C  Y+  N  YW  RA     + F  R+            VAVF+LK FM+ VVGI S +W+ S  ++  W+  +   L   T +K   S S
Sbjct:   22 LEIGAYDLEHGRPGKCEPITIPMCQGIGYNMTRMPNLLNYESQEEASIKLNEFAPLVKYGCDIHLQFFLCSLYVPMCAEQVSASIPACRPMCEQARQRCSPIMEQFSFSWPDSLDCSKLPTNNDPNALCIEAPENDTQPETKKGEGMLPVPPRS--RQPTTVSGRISSISQSCENPEKFQYVDKSESCAPRCTPTVDVYWSRQDKDFAFIWMVVWSTLCFVSTAFTVLTFLLDPQRFQYPERPIIFLSMCYNIYSVAFIIRSVAGAENIACDRE--NGELYIIREGLESTGCTIVFLILYYFGMASSIWWVILTLTWFLAAGRKWGHEAIEAHSSYFHMAAWGIPAVKTIVILTMRKVAGDELTGLCYVGSMDSSALTGFVLIPLSCYLIVGTSFILTGFVAL-FHIRKIMKTGGTNTEKLEKLM---VKIGVFSILYTVPATIVIICYFYERLNMEYWKFRALENKCVSFPGRRSDDCSLDSSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQGLYNRRLGVQTSHKPCSSVS 552          

Query:   91 ICLFLLISIVDSI----ENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNS 1644
            +CL LL  +V  I    + E+ +  PI I  CQN  YN T +      + +A+ ++ + T+  L+  GCS  L F LCSVYVP C     I + PC  +C  V+  CEP+LK    +WPE LNCS+FP ++ H   CM    ++ +   +  +   L  +  N   P           N ++Y ++ R+  C LKC  ++  +S+ SK   +IWM V  SL F+ST FT +TF   + R  YPE+PIIFL+  YNIYSI+ ++RL +GRE++SCDF+  + + +LIQEGL+NT CAI FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +V T+ +LI+R VDADEL GLC VG Q  D L  F + P    L+IG +F+ +G     ++ +    K      K+  L+    ++G+FS++Y +    +I C  Y+  N++ +           D+ +AV +L  FM+ +VGI S +WI S  ++  W+KC   L+      +K + + 
Sbjct:    8 LCLPLLGCLVGHIAGFGDEEERRCDPIRISMCQNLGYNVTKMPNLVGHELQADAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDDEV--PVHSKTPVLPGEDCNSFGP-----------NSDQYTWVKRSMNCVLKCGYDSGLYSRLSKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFCYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEE-AAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNIDALTGFVVAPLFTYLVIGTLFIAAGLVAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSVLYTVPATCVIACYFYEISNWNVFRYT------ADDSNMAVEMLNIFMSLLVGITSGMWIWSAKTLHTWQKCTNRLVNSGKVKRKKRVDG 511          

Query:  109 ISIVDSIENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMH-PSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKC--SENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFC-HNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYW-SRA------PIKFSKRKD-------AIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            + + D     + K +PI I  CQ   YN T +      + + E    ++ +  L+  GC  HL F LCS+Y P C       +  C+ +CE  +  C PI++     WPE L+C R P ++     CM  P    N         +     R          G      N +K++++ R+G CA +C    + ++S   K  A +WM   + L F+ST FT  TF  H +R +YPE+PIIFL+  YN+YS + L+R   G   ++CD +   G   LI+EGLE++ C + FL+ ++F  A+ +WW++L L W L  +      ++  +   FHL  W + ++ T+ +L +R V  DEL GLC VG   P  L  F ++P    L+ G  FLL+GF    +  ++       + +K+  L+    ++G+FSI+Y +    +I C  Y+  N  +W SRA       +  S R D         VAVF+LK FM+  VGI S +W+ S  ++ AW+
Sbjct:   15 MGLYDVERGREAKCEPIQIPMCQGIGYNMTRMPNYVGHESQEEAAAKLQEFAPLVEYGCHIHLRFFLCSLYAPMCTEQVSTSIPACKPMCEAARQKCAPIMESFQYVWPESLDCDRLPSKNDPHALCMEAPENATNGDPPTNGHGMLPVAPRPP-RPSGSGIGISSRCANPDKFMYVERSGVCAPRCIPGVDVYWSSGDKDFALVWMAAWSGLCFISTAFTVFTFLLHPQRFQYPEKPIIFLSMCYNVYSTAFLIRAAAGAPSIACDRE--GGAPYLIREGLESSGCTLVFLILYYFGMASSLWWVVLTLTWFLAASKKWGHEAIESHGSYFHLAAWGIPAIKTIIILTMRKVGGDELTGLCYVGGSDPSALTGFVLVPLSCYLVTGTSFLLTGFVAL-FHIRRVMKTGGTNTEKLEKLM---VKIGVFSILYTVPATCIIVCCFYERLNLAHWDSRAREESCRTVPGSARPDCNLPHSIPSVAVFMLKIFMSLAVGITSGVWVWSSKTLQAWQ 521          

Query:   94 CLFLLISIVDSIENEKCKP------KPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCM-HPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRG-----------------QCRHMR---NGEKYVFINR--TGR---CALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA--------PIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            CL+LL+  V  ++  +C        + I +  C++  YN+T +    + D + E  + +  +  L+   CS  L F LCS+Y P C  D    L PCR VCE+ +  C P+++    +WP+++ C R P + +    CM + ++ E                R+    PK                     QCR        E++   NR  TG+   CA+ C  N +FS E +T  E W+ + + L F ST  T  TF  +  R +YPE+PIIFL+  Y + S   L+RL  G EKV+C    +  + I+  E      C + FLL +FF  A+ +WW++L L W L   +     ++A  S  FHL  WL+ S+ +++VL L SVD D + G+C VG Q  D L  F + P +I L IG +FLL+GF    +R +    +      K+  L+    R+G+FS++Y +    ++ C  Y+ +N   W  A         +   +R D   AVF+LK+FM  VVGI S +WI S  ++ +W+ 
Sbjct:    3 CLYLLLLAVSWLQGSQCAAAKELSCQEITVPLCKDIGYNYTYMPNQFNHDTQDEAGMEVHQFWPLVVIHCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERARAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYYNRTEQTTAAPSHPEPPKPPARS---APKGRTRVEPPRPRPRAPGCEPGCQCRAPMVPVTNERHPLYNRVRTGQIPNCAMPC-HNPYFSPEERTFTEFWIGLWSVLCFASTFATVSTFLIDMERFKYPERPIIFLSACYLLVSAGYLVRLIAGHEKVACSRGELDLEHIIHYETTGPALCTLVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSIKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVIYLFIGSMFLLAGFVSL-FRIRSVIKQGGTKTDKLEKLM---IRIGIFSVLYTVPATIVVACFFYEQHNRQGWEVAHNCNSCQPEVAQPRRPD--YAVFMLKYFMCLVVGITSGVWIWSGKTLESWRA 535          

Query:  157 IAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINR--TGR---CALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA-----PIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            I +  C+   YN T +    + D + E  + +  +  L+   CS  L F LCS+Y P C  D    L PCR VCE+ +  C P+++    +WPE++NC R P        CM  +  E            +    ++     + R     +   E +   NR  TG+   CA+ C +  +F+++ KT A  W+ + + L F+ST  T  TF  +  R RYPE+PIIFL+  Y   SI  ++RL +G E V+C+ D +        E      C + FLL +FF  A+ +WW++L   W L   +     ++A  S  FH+  WL+ SV +++VL L SVD D + G+C VG Q  D L  F + P ++ L  G +FLL+GF    +R +    +      K+  L+    R+G+FS++Y +    ++ C +Y+ +   +W +A     P    KR     AVF+LK+FM  VVGI S +WI S  ++ +WK+
Sbjct:   36 ITVPMCKGIGYNHTYMPNQFNHDTQDEAGMEVHQFWPLVVIQCSLDLKFFLCSMYTPICLPDYRKPLPPCRSVCERAKAGCSPLMRKYGFAWPERMNCDRLPEHGDPDTLCMDYNWTETTTTPPPTHPPKVKTPSSDCDGVCKCREPFLSITR-ESHPLYNRIKTGQVPNCAMPCFQ-PYFTQDEKTFATFWIGLWSILCFISTFTTVATFLIDMERFRYPERPIIFLSACYLFVSIGYIVRLIVGHENVACNKDHIH------YETTGPALCTVVFLLIYFFGMASSIWWVILTFTWFLAAGMKWGNEAIASYSQYFHMAAWLIPSVKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVVYLFTGTMFLLAGFVSL-FRIRSVIKQGGTKTDKLEKLM---IRIGIFSVLYTVPATIVVACYIYEQHYREHWEKAHNCSCPGD-KKRYRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWKR 514          

Query:  151 KPIAIGQCQNKFYNFTS----LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGR--CALKC--SEND---FFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFD-PVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA-------------PIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVML 1602
            +PI+I  C +  YN T     L    + +  + +  +  L+   CS  L F LCS+Y P C       + PCR +CE+ +  CE ++      WPE+L C  FP   + Q+       E+     +             I+    +   C  +     Y+     G   CA  C  S+ND   FFS++    A +W+ + + L   ST FT  T+  + +R RYPE+PIIFL+  Y + S++ +    LG +KV C+ +    G K ++Q G +   C I F++ +FFS A+ +WW++L L W L   +     ++  NS  FHL  W + +V T+++L +  +D D L G+C VG    D L  F + P  + L IG  FLL+GF    +R +          +K+  L+    R+G+FS++Y +    +I C  Y+     +W R+             P++++ R      V+++K+ M  +VGI S  WI S  ++ +W+K +  L
Sbjct:   41 QPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSSELRFFLCSMYAPVCTVLEQ-AIPPCRSICERARHGCEALMNKFGFQWPERLRCENFPRHGAEQICVGQNHSEDGGPTLLTTSPPHHGTPGPPIYATLDHPFHCPRVLKVPSYLNYRFLGEKDCAAPCEPSKNDGFMFFSQDEIRFARVWILIWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLG-DKVVCNENFSEDGYKTVVQ-GTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNNIDPLRGFVLAPLFVYLFIGTSFLLAGFVSL-FRIRTIMKHDGTKTEKLERLM---VRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQNCKSLAIPCPLQYTPRMTPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRL 543          

Query:  130 ENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMH-PSQEE-NLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHM-RNGEKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNS 1644
            + E+ +  PI I  CQN  YN T +      + + + ++ + T+  L+  GCS  L F LCSVYVP C     I + PC  +C  V+  CEP+L+    +WP+ LNCS+FP ++ H   CM  P  EE  L  K  IQ             P +   +C  +  N ++Y+++ R+  C LKC  +   +S+ +K   +IWM V  SL F+ST FT +TF   + R  YPE+PIIFL+  YNIYSI+ ++RL +GRE++SCDF+  + + +LIQEGL+NT CAI FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +V T+ +LI+R VDADEL GLC VG Q  D L  F + P    L+IG +F+ +G     ++ +    K      K+  L+    ++G+FS++Y +    +I C  Y+  N+     A  ++S   D+ +AV +LK FM+ +VGI S +WI S  ++  W+KC   L+      ++ + N 
Sbjct:   39 DEEERRCDPIRIAMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLREFGFAWPDTLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQ-------------PGE---ECHSVGSNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTTFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAA-EPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSVLYTVPATCVIACYFYEISNW-----ALFRYSA-DDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNG 525          

Query:  148 PKP---IAIGQCQNKFYNFTS----LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSL----NKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSEND--FFSKESKTIAEIWMKVITSLTFVSTLFTCVTFC-HNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYW---------SRAPIKFSKRKDAI-------VAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQ 1668
            P P   + I  C+   YN T     L    + E    +  +  L+  GC  HL F LCS+Y P C       +  CR +CE+ +  C PI++  N  WP+ L+C+R P  +     CM   +          + L +     +      +     G      N EK+ ++ ++  CA +C      F+S+  K  A +WM V ++L F ST FT  TF     R +YPE+PIIFL+  YN+YS++ L+R   G + V+CD +  +G   +IQEGLENT C + FLL ++F  A+ +WW++L L W L         ++  +   FH+  W + ++ T+ VL LR V  DEL GLC V    P  L  F ++P    L++G  FLL+GF    +  +K       + +K+  L+    ++G+FSI+Y +    +I C +Y+  N  +W         + A +   +R  ++       VAVF+LK FM+ VVGI S +W+ S  +   W+    +   K+   +      R    YG+
Sbjct:   37 PAPCQAMEIPMCRGIGYNLTRMPNLLGHTSQGEAAAQLAEFSPLVQYGCHSHLRFFLCSLYAPMCTDQVSTPIPACRPMCEQARLRCAPIMEQFNFGWPDSLDCARLPTRNDPHALCMEAPENATAGPTEPHKGLGMLPVAPRPARPPGDSAPGPGSGGTCDNPEKFQYVEKSRSCAPRCGPGVEVFWSRRDKDFALVWMAVWSALCFFSTAFTVFTFLLEPHRFQYPERPIIFLSMCYNVYSLAFLIRAVAGAQSVACDQE--AGALYVIQEGLENTGCTLVFLLLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEAHGSYFHMAAWGLPALKTIVVLTLRKVAGDELTGLCYVASMDPAALTGFVLVPLSCYLVLGTSFLLTGFVAL-FHIRKIMKTGGTNTEKLEKLM---VKIGVFSILYTVPATCVIVCYVYERLNMDFWRLRATEQPCTAATVPGGRRDCSLPGGSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTFQTWQS---LCYRKMAAGRARAKACRTPGGYGR 564          

Query:  109 ISIVDSIENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMH--------PSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSE--NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYW--------------SRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            IS +D       K +P+ I  C++  YN T +      + + E  I +  +  L+  GC  HL F LCS+Y P C       +  CR +CE+ +  C PI++     WP+ L+CS+ P ++     CM         PS+   +   +       +   + + +    R  C    N  K+  + ++  CA  C+   + ++S++ K  A +W+ + + L F S+ FT +TF  +  R RYPE+PIIFL+  Y +YS+  ++RLF G E ++CD D  SGQ  +IQEGLE+T C + FL+ ++F  A+ +WW++L L W L         ++  NS  FHL  W + +V T+ +L++R V  DEL G+C VG    + L  F ++P    L+IG  F+LSGF    +  ++       +  K+  L+    R+G+FS++Y +    +I C  Y+  N  YW              ++ P          V VF++K  M  VVGI S +W+ +  ++ +W+
Sbjct:   22 ISSMDLERPGDGKCQPVEIPMCKDIGYNTTRMPNLMGHENQREAAIQLHEFAPLVEYGCHSHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSPIMEQFKFRWPDSLDCSKLPNKNDPNYLCMEAPNNGSDEPSRGSGMFPPLFRPQRPHSAQEHPLKDGGPGRAGCD---NPGKFHHVEKSESCAPLCTPGVDVYWSRDDKRFAVVWLAIWSVLCFFSSAFTVLTFLIDPSRFRYPERPIIFLSMCYCVYSVGYIIRLFAGAESIACDRD--SGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLVPLACYLVIGTSFILSGFVAL-FHIRRVMKTGGENTDKLEKLM---VRIGVFSLLYTVPATCVIACYFYERLNMDYWKMLATQHKCKMNNQTKTPDCLMTTSIPAVEVFMVKVSMLLVVGITSGVWVWTSKTLQSWQ 533          

Query:  157 IAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFP-LESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNG-----EKYVFI----------NRTGR---CALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA-------PIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            I +  C+   YN T +    + D + E  + +  +  L+   CS  L F LCS+Y P C  D    L PCR VCE+ +  C P+++    +WPE+++C R P L    ++ CM  ++ E        ++                 G+C           E +V I           RTG+   CA+ C +  F S + +T A  W+ + + L F+ST  T  TF  +  R RYPE+PIIFL+  Y   S+  L+RL +G   V+C  +       +  E      C + FLL +FF  A+ +WW++L L W L   +     ++A  +  FHL  WL+ SV +++ L L SVD D + G+C VG Q  + L  F + P ++ L++G +FLL+GF    +R +    +      K+  L+    R+G+F+++Y +  + ++ C LY+ +    W  A       P     R      V +LK+FM  VVGI S +WI S  ++ +W++
Sbjct:   36 ITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVLCMDYNRSE--ATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSF-SPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSRE----HSHIHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSL-FRIRSVIKQGGTKTDKLEKLM---IRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGPDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESWRR 532          

Query:  157 IAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFP-LESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNG-----EKYVFI----------NRTGR---CALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA-------PIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            I +  C+   YN T +    + D + E  + +  +  L+   CS  L F LCS+Y P C  D    L PCR VCE+ +  C P+++    +WPE+++C R P L    ++ CM  ++ E        ++                 G+C           E +V I           RTG+   CA+ C +  F S + +T A  W+ + + L F+ST  T  TF  +  R RYPE+PIIFL+  Y   S+  L+RL +G   V+C  +       +  E      C + FLL +FF  A+ +WW++L L W L   +     ++A  +  FHL  WL+ SV +++ L L SVD D + G+C VG Q  + L  F + P ++ L++G +FLL+GF    +R +    +      K+  L+    R+G+F+++Y +  + ++ C LY+ +    W  A       P     R      V +LK+FM  VVGI S +WI S  ++ +W++
Sbjct:   36 ITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVLCMDYNRSE--ATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSF-SPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSRE----HSHIHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSL-FRIRSVIKQGGTKTDKLEKLM---IRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGPDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESWRR 532          

Query:  130 ENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMH-PSQEE-NLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHM-RNGEKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNS 1644
            + E+ +  PI I  CQN  YN T +      + + + ++ + T+  L+  GCS  L F LCSVYVP C     I + PC  +C  V+  CEP+LK    +WPE LNCS+FP ++ H   CM  P  EE  L  K  IQ             P +   +C  +  N ++Y+++ R+  C LKC  +   +S+ +K   +IWM V  SL F+ST FT +TF   + R  YPE+PIIFL+  YNIYSI+ ++RL +GRE++SCDF+  + + +LIQEGL+NT CAI FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +V T+ +LI+R VDADEL GLC VG Q  D L  F + P    L+IG +F+ +G     ++ +    K      K+  L+    ++G+FS++Y +    +I C  Y+  N+     A  ++S   D+ +AV +LK FM+ +VGI S +WI S  ++  W+KC   L+      ++ + N 
Sbjct:   39 DEEERRCDPIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQ-------------PGE---ECHSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAA-EPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSVLYTVPATCVIACYFYEISNW-----ALFRYSA-DDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNG 525          

Query:  130 ENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMH-PSQEE-NLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHM-RNGEKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNS 1644
            + E+ +  PI I  CQN  YN T +      + + + ++ + T+  L+  GCS  L F LCSVYVP C     I + PC  +C  V+  CEP+LK    +WP+ LNCS+FP ++ H   CM  P  EE  L  K  IQ             P +   +C  +  N ++Y+++ R+  C LKC  +   +S+ +K   +IWM V  SL F+ST FT +TF   + R  YPE+PIIFL+  YNIYSI+ ++RL +GRE++SCDF+  + + +LIQEGL+NT CAI FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +V T+ +LI+R VDADEL GLC VG Q+ D L  F + P    L+IG +F+ +G     ++ +    K      K+  L+    ++G+FS++Y +    +I C  Y+  N+     A  ++S   D+ +AV +LK FM+ +VGI S +WI S  ++  W+KC   L+      ++ + N 
Sbjct:   40 DEEERRCDPIRIAMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPDSLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQ-------------PGE---ECHSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTTFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAA-EPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQSLDALTGFVVAPLFTYLVIGTLFIAAGLVAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSVLYTVPATCVIACYFYEISNW-----ALFRYSA-DDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNG 526          

Query:  130 ENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMH-PSQEE-NLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHM-RNGEKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKC 1590
            + E+ +   I I  CQN  YN T +      + +A+ ++ + T+  L+  GCS  L F LCSVYVP C     I + PC  +C  V+  CEP+LK    +WP+ LNCS+FP ++ H   CM  P  EE  L  K  +Q             P +   +C  M  N ++Y+++ R   C LKC  +   +S+ +K   +IWM V  SL F+ST FT +TF   + R  YPE+PIIFL+  YNIYSI+ ++RL +GRE++SCDF+  + + +LIQEGL+NT CAI FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +V T+ +LI+R VDADEL GLC VG Q  D L  F + P    L+IG +F+ +G     ++ +    K      K+  L+    ++G+FS++Y +    +I C  Y+  N+     A  ++S   D+ +AV +LK FM+ +VGI S +WI S  ++  W+KC
Sbjct:   27 DEEERRCDAIRIAMCQNLGYNVTKMPNLVGHELQADAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPDSLNCSKFPPQNDHNHMCMEGPGDEEVPLHSKTSLQ-------------PGE---ECHSMGSNSDQYIWVKRNLDCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAA-EPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSVLYTVPATCVIACYFYEISNW-----AVFRYSA-DDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKC 495          

Query:  130 ENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMH-PSQEE-NLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHM-RNGEKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNS 1644
            + E+ +  PI I  CQN  YN T +      + + + ++ + T+  L+  GCS  L F LCSVYVP C     I + PC  +C  V+  CEP+L+    +WP+ LNCS+FP ++ H   CM  P  EE  L  K  IQ             P +   +C  +  N ++Y+++ R+  C LKC  +   +S+ +K   +IWM V  SL F+ST FT +TF   + R  YPE+PIIFL+  YNIYSI+ ++RL +GRE++SCDF+  + + +LIQEGL+NT CAI FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +V T+ +LI+R VDADEL GLC VG Q  D L  F + P    L+IG +F+ +G     ++ +    K      K+  L+    ++G+FS++Y +    +I C  Y+  N+     A  ++S   D+ +AV +LK FM+ +VGI S +WI S  ++  W+KC   L+      ++ + N 
Sbjct:   39 DEEERRCDPIRIAMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLREFGFAWPDTLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQ-------------PGE---ECHSVGSNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTTFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAA-EPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSVLYTVPATCVIACYFYEISNW-----ALFRYSA-DDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNG 525          

Query:  130 ENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTF-CHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNS 1644
            E E+    PI I  CQN  YN T +      + +A+ ++ + T+  L+  GCS  L F LCSVYVP C     I + PC  +C  V+  CEP+LK    +WPE LNCS+FP ++ H   CM    ++ +    +   L   +D N+               N ++Y ++ R+  C LKC  ++  +++ SK   +IWM V  SL F+ST FT +TF   + R  YPE+PIIFL+  YNIYSI+ ++RL +GRE++SCDF+  + + +LIQEGL+NT CAI FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +V T+ +LI+R VDADEL GLC VG Q  D L  F + P    L+IG +F+ +G     ++ +    K      K+  L+    ++G+FS++Y +    +I C  Y+  N++ +           D+ +AV +L  FM+ +VGI S +WI S  ++  W+KC   L+      +K + + 
Sbjct:   25 EEEERSCDPIRITMCQNLGYNVTKMPNLVGHELQADAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDDEVPAHSKTPVLP-GEDCNSFGP------------NSDQYTWVKRSMNCVLKCGYDSGLYNRLSKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFCYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEE-AAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNIDALTGFVVAPLFTYLVIGTLFIAAGLVAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSVLYTVPATCVIACYFYEVSNWNVFRYT------ADDSNMAVEMLNIFMSLLVGITSGMWIWSAKTLHTWQKCTNRLVNSGKVKRKKRVDG 511          

Query:   67 MIKLPPVNICLFLLISIVDSIENEKCKPKPIAIGQCQNKFYNFTSLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQLNSTNSNKYWLYCKSGN 1719
            MIKLPPVNICLFLLISIVDSIENEKCKPKPIAIGQCQNKFYNFTSLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQLICLIIGFIFLLSGFFFFKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSIIYIIAIATMICCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQLNSTNSNKYWLYCKSGN
Sbjct:    1 MIKLPPVNICLFLLISIVDSIENEKCKPKPIAIGQCQNKFYNFTSLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQLICLIIGFIFLLSGFFFFKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSIIYIIAIATMICCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQLNSTNSNKYWLYCKSGN 551          

Query:  115 IVDSIENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCM-HPSQEENLQRK-IQIQNLSLNKDRN--NIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCF 1593
            I+  +   KCKP+ I   QC++KFY +TSL     QDQE ++QI ++T+R LL++ CS  LNFLLCSVY P CD +  I L PC  +CEKVQ +CEPILK+ NL WP  LNCSRFP +S+ ++ CM +P  +    R  +Q+ N+ +NK+    NIH      G+CRH+R+ EKYVFINRTG+CALKCSEND FS+ESK  AE+WM V+  +TF+STLFTC+TFCH+ +I+YPEQPIIFLT SYN+YS+S+LLRLF  R  VSCD+DPVSGQ ILIQEGLENT CAITFLLNFFF+ ATH+WW+ L  CW L+    VS+ +L  N+G FHLFVWL TS+LTVS+LILR V+ADEL G+CSVG Q+P+LL+TFSIIP+ ICLI+G + L  GF F K R KK  NK+    + IT + S+ FR+G+FS IYI+AI+  I CELYQY NY+ W RAP  F   K+ IVA+FLL  FM QVVGINSAIWI SLD+  +WK  F
Sbjct:   23 ILSVVTTRKCKPQIIRAEQCRDKFYKYTSLPNLMGQDQEMDIQIQMDTFRPLLNHKCSNELNFLLCSVYTPICDPEAEILLGPCAGICEKVQTECEPILKIFNLPWPSGLNCSRFPSQSTPELMCMSNPVFDSRSTRNPLQLFNV-VNKEGFVFNIHH-----GRCRHLRHSEKYVFINRTGKCALKCSENDLFSQESKRFAEMWMSVLAVITFLSTLFTCMTFCHSNKIKYPEQPIIFLTLSYNLYSVSLLLRLFFTRSTVSCDYDPVSGQYILIQEGLENTYCAITFLLNFFFNIATHIWWVTLTSCWMLYSVFKVSSFNLKINAGYFHLFVWLSTSMLTVSILILRCVEADELLGICSVGGQSPELLMTFSIIPKSICLIVGTLLLCLGFLFLKTR-KKTINKNGKKIRSITHITSVAFRMGIFSGIYILAISIHIVCELYQYINYNIWRRAPQIFRDIKEPIVAIFLLNIFMGQVVGINSAIWIWSLDAATSWKSVF 516          

Query:  136 EKCKPKPIAIGQCQNKFYNFTS----LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQ------YRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKF-SNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQLNSTNSNKYWLYCKS 1713
             KC P+ I + QC+++FY +T      S +Q   +   I+ Y SLL   CSK L FLLCS   PFCD ++ + +  C   C+ VQ +C   +KL+NLSWP++LNCS+FP+E+  + +C+   +    +R++ + +  + +   NI+E         Y  +C H+R+ EKY+FINRTGRCALKCSEND FS+  K +AEIWM  +  LTF+ST+FTC+T CHN +I+YPEQPIIFLTFSYN+YS+S+LLRLF  R  VSCDFD V+ Q ILIQEGLENT+CAITFLLN+FFSTATH+WW+ L  CW L+    VS  +L  NSG FHLFVWL TS+LTV+VL+LR V+ADEL G+CSVG Q+PD L+TFSIIP+L+CLI+G   L  GF F K   +K  SN         +    +  R+GLFS IY+ A    I CE YQY NY  W             +VA+FLL  FMNQ+VGINS++WI SLD+  +W+K F  L       K     +++ E   + NS  S+K   Y KS
Sbjct:   30 RKCIPQLIKVKQCRSQFYKYTHSQNLTSLNQVKNIDSEIDKYLSLLKGKCSKDLLFLLCSNLTPFCDPNSKLLVPLCGTTCKNVQKECGFEIKLLNLSWPKELNCSQFPIENEPKSRCISIPR---FERQVPLNSKEIVETFTNINEKLFVNRNLFYLKKCGHLRHSEKYIFINRTGRCALKCSENDLFSRRMKKVAEIWMSSLAVLTFLSTMFTCLTCCHNSKIKYPEQPIIFLTFSYNLYSVSLLLRLFFTRSIVSCDFDQVTNQYILIQEGLENTHCAITFLLNYFFSTATHIWWVALTFCWMLYNVFKVSVSNLTNNSGYFHLFVWLPTSMLTVTVLVLRCVEADELLGVCSVGGQSPDRLMTFSIIPKLVCLILGMFLLFVGFIFLKPEEEKMKSNSQNIFRWSTSSTSKVSCRIGLFSCIYVTATFISIVCEFYQYVNYVRWKIQLKIEESTAQPLVAIFLLNIFMNQIVGINSSVWIFSLDAAKSWRKFFATLKSLCAKKKHKNLMNKQKEINQKTNSNESSKLCTYTKS 563          

Query:  121 DSIENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCM-HPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNR-RIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLL------------EKVTFNKKI---KSNSREIESYGQLNSTNSNKYWLYCKSGN 1719
            D I+ +KC+PK I + +CQ+ FYNFT++    + + + E Q  + T++SL+   CS  L F LC+VY+P CD ++   + PCR +CE+V+  CE I+K  +LSWP  LNCSRFP  ++    CM  P   E ++                     + +  C  M+N   +V+INRT +C  KC  N  F+ + K IA+IW+ V++SL F+S++FT +TF  N  R +YPE+P+IFL   Y++YS+S  +RL   R+  SC+ DPV+GQ IL QEGLENT CAI FLLN+FF+ A+ +WW++L L W L      S  ++ + SG FHLF WL++S+LTVSVL+LRSVDADEL GLCSVG+QT   LL F IIP +I L+IG +FLLSG      R ++          K+  L+    R+GLFS++++I  +T++ C +Y+Y N  +W       +      + +F+LK FM  VVGI S +W+ S+ ++ +WK  FV+ L            +K  FNK I    + SRE  +    N+ N       C SGN
Sbjct:   35 DPIQTKKCQPKRIIVQECQHLFYNFTAMPNLINHETQIEAQTQLLTFQSLIKYKCSAKLLFFLCAVYIPMCDPNSHYLIGPCRPLCEEVRDSCEKIMKPFSLSWPVNLNCSRFPKSNTEGSMCMVGPGPSEKVE---------------------EVKVNCEKMKNPSSFVYINRTQKCVPKCMANILFNSDDKYIAKIWLAVLSSLCFISSMFTILTFLINTDRFKYPERPVIFLAVCYSLYSVSHFIRLLHNRKGSSCNRDPVTGQYILTQEGLENTMCAIIFLLNYFFAIASQIWWVILTLTWLLAAGFKWSEEAIYQRSGYFHLFAWLISSLLTVSVLVLRSVDADELLGLCSVGQQTASSLLIFVIIPNIIFLVIGCMFLLSGLIAL-VRVRRHVKNDGIKTDKLEILM---VRIGLFSVLFLIPSSTVLACNIYEYVNKDFW------LTSGTTPNIEIFMLKIFMASVVGITSGVWVWSIKTLDSWKWFFVVKLCRRQPSRSVIENKKNNFNKTIGYMPATSRENIALEANNNRN-------CWSGN 550          

Query:  115 IVDSIENEKCKPKPIAIGQCQNKFYNFTSLSQ----DQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNR-RIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            +++ ++  KC PK I + +CQN FYNFT +      + + E Q  ++T++SL+   CS++L F LCSVY+P CD  +   + PC+ +CE+V+  CE I++  NL WP  LNCSRFP+ ++    CM                        ++   + ++  C  M+N   ++FINRT +C  KCS N  F+ + K IA+IW+ V+ SL F+S++FT +TF  N  R +YPE+P+IFL   Y+IYS+S  + L   R+  +C+ DPVSGQ IL QEGL+NT CAI FLLNFFFSTA+ +WW++L + W L      S  ++ + SG FHL  WL++S+LTV+VL+LRSVDADEL GLCSVG+Q    LL F IIP +I L+IG  FLL G      R ++         +K+  L+    R+GLFS+++++  +T++ C  Y+Y N  +W ++        +  + V++LK FM+ VVGI S +W+ S+ ++ +W+
Sbjct:   37 VLEPVQTRKCLPKKILVPECQNLFYNFTGMPNLVNLETQIEAQSQLQTFQSLIKYKCSQNLLFFLCSVYIPMCDPISNYLIGPCQPLCEEVRDSCERIMRPFNLPWPVTLNCSRFPVRNAEGSMCMEGPGP-------------------SVKSTENFQTMCGGMKNPRLFIFINRTQKCVPKCSANILFTVDDKYIAKIWLTVLASLCFISSVFTILTFLINTDRFKYPERPVIFLAVCYSIYSVSHFINLANTRQSAACNRDPVSGQFILTQEGLDNTLCAIIFLLNFFFSTASQIWWVILTVAWLLAAGFKWSEEAIYQRSGYFHLAAWLISSLLTVAVLVLRSVDADELLGLCSVGQQNVSTLLIFVIIPNIIFLVIGCFFLLGGLVAL-VRVRRHVKNDGIKTEKLEILM---VRIGLFSVLFLVPSSTVLGCNFYEYANRDHWLKS------GTNPNIEVYMLKIFMSSVVGITSGVWVWSIKTLESWQ 502          

Query:  133 NEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNG--EKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFC-HNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLE 1608
            +E  + +PI +  C +  YN T +        +A+ ++ ++T+  L+  GCS  L F LC+VY P C     + + PC  +C  V+  C P+L+     WPE LNCS FP  +     CM    E++L           NK      E      +C  M  G  E+Y +  R+G C L+C  E+  + +++K   ++WM V   L F+ST FT +TF   + R  YPE+PI+FL+  YN+YS++ L+RL  GRE++SCD D  +   +L QEGL+NT CA+ FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +V T+ +LI+R VDAD+L GLC VG Q  D L  F + P    L+IG +F+ +G     ++ +    K      K+  L+    ++G+FS++Y +    +I C  YQ  N+  + +        +D+ +A  +L+ FM+ +VGI   +W+ S  ++  W++C + LL 
Sbjct:   27 DEDARCEPIRMAMCLDLGYNQTRMPNLVGNVLQADAELQLQTFTPLIQYGCSSQLKFFLCAVYAPMCTEKVPVTIGPCGSMCLAVKRKCLPVLQEFGFVWPELLNCSLFPPTNDQNHMCMEGPAEDDL--------FHPNKPVAPHEE------ECVTMGGGGPEQYAWAKRSGSCVLQCGYESGLYRRQAKMFTDVWMAVWAVLCFISTSFTVLTFLLDSARFSYPERPIMFLSMCYNVYSVAFLVRLTAGRERISCDLDEAA-VPVLAQEGLKNTGCAVVFLLAYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADDLTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSVLYTVPATCVIACYFYQISNWADFHQ------TARDSYMAAEMLRIFMSLLVGITCGMWVWSAKTLHTWQRCSLRLLH 501          

Query:  103 LLISIVDSIENEKCKPKPIAIGQCQNKFYNFTSLSQ----DQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDR-----NNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSE--NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWS-RAP----IKFSKRKD---------AIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            L I   D       K +PI I  CQ   YN T +      + + E  I +  +  L+  GC  HL F LCS+YVP C       +  CR +C + +  C PI++  +  WP+ L+CS+ P  +     C+   + + +    + + +     R          P    G C    N EK+ ++ ++  CA +CS   + F+S++ K  A IWM V ++L FVST FT +TF  + +R +YPE+PIIFL+  YN+YS++ ++R   G E ++CD +  +GQ  +IQEGLE+T C I FL+ ++F  A+ +WW++L L W L         ++  +S  FH+  W + ++ T+ +L +R V  DEL GLC VG    + L  F IIP    LIIG  F+L+GF    +  +K       + +K+  L+    ++G+FSI+Y +    +I C  Y+  N  YW  RA     + F  R+            VAVF+LK FM+ VVGI S +W+ S  ++  W+
Sbjct:   36 LDIGAYDGERGRPAKCEPITIPMCQGIGYNMTRMPNFMKYESQEEASIKLNEFAPLVEYGCDVHLRFFLCSLYVPMCTDQVSTTIPACRAMCVQARQKCSPIMEQFSFGWPDSLDCSKLPTNNDPNALCIEAPENDTVPPTKKGEGMLPVPARPRPPGTGAGRPSGGSGSCE---NHEKFQYVEKSESCAPRCSPTVDVFWSRQDKDFAFIWMVVWSTLCFVSTAFTVLTFLLDPQRFQYPERPIIFLSMCYNVYSVAFIIRSVAGAENIACDRE--NGQLYIIQEGLESTGCTIVFLILYYFGMASSIWWVILTLTWFLAAGRKWGHEAIEAHSSYFHMVAWGIPAMKTIVILTMRKVAGDELTGLCYVGSMDTNALTGFIIIPLSCYLIIGTSFILTGFVAL-FHIRKIMKTGGTNTEKLEKLM---VKIGVFSILYTVPATCVIICYFYERLNMDYWKFRASESKCVSFPGRRTEDCTLDSSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQ 546          

Query:  118 VDSIENEKCKP---KPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNL--SLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSE--NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYW-----SRAPIKFSKRKD---------AIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            + S + E+ +P   +PI I  CQ   YN T +      D + E  I +  +  L+  GC  HL F LCS+Y P C       +  CR +CE+ +  C PI++  N +WPE L+CS+ P  +     CM   + +      + + +     + R       +  G      N EK+ ++ ++  CA +CS   + F+S++ K  A IWM V ++L FVST FT +TF  +  R +YPE+PIIFL+  YN+YS++ ++R   G E ++CD +  +G+  +IQEGLE+T C I FL+ ++F  A+ +WW++L L W L         ++  +S  FH+  W + ++ T+ +L +R V  DEL GLC VG      L  F ++P    L++G  F+L+GF    +  +K       + +K+  L+    ++G++SI+Y +    +I C  Y+  N  YW         + F  R++           VAVF+LK FM+ VVGI S +W+ S  ++  W+
Sbjct:   29 IGSYDFERGRPAKCEPIVIPMCQGIGYNLTRMPNFMDHDSQKEAAIKLNEFAPLVEYGCDVHLRFFLCSLYAPMCTDQVSTSIPACRPMCEQARQRCSPIMEKFNYAWPESLDCSKLPTRNDPNALCMEAPENDTKPEPKKGEGMLPVPPRPRQPGSGGGRPGGSVGACENPEKFQYVEKSESCAPRCSSAVDVFWSRQDKDFAFIWMAVWSTLCFVSTAFTVLTFLLDPHRFQYPERPIIFLSMCYNVYSVAFIIRSVAGAENIACDRE--NGELYIIQEGLESTGCTIVFLILYYFGMASSIWWVILTLTWFLAAGKKWGHEAIESHSSYFHMAAWGIPALKTIVILTMRKVAGDELTGLCYVGSMDVGALTGFVLVPLSFYLVVGTSFVLTGFVAL-FHIRKVMKTEGTNTEKLEKLM---VKIGIYSILYTVPATCVIVCYFYERLNMDYWKFRGLESKCVTFPGRRNEDCSLDASMPAVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQ 537          

Query:  202 LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHP----SQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKC-SEND-FFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIK------------FSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCF 1593
            +  + + E  I +  +  L+  GC  HL F LCS+Y P C       +  CR +CE+ +  C PI++  N  WP+ L+CSR P ++     CM      S + +     Q  +    +  N+   P + R       N  K+ F+ ++  CA KC S+ D ++S   K  + +W+ + + L F+S+ FT +TF  + +R +YPE+PIIFL+ SY +YS+  L+RLF+G E V+CD D  SG + +IQEGLE+T C I FL+ ++F  A+ +WW++L L W L         ++  NS  FHL  W + ++ T+ +L++R V  DEL G+C VG      L  F +IP    LIIG  FLLSGF    +  +K       +  K+  L+    R+G+FS++Y +    +I C  Y+  N  YW     +              K     V +F++K FM  VVGI S +WI +  ++ +W+  F
Sbjct:    5 MGHEDQGEAAIKLHEFAPLIEFGCHSHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARQKCSPIMEQFNFHWPDSLDCSRLPNKNDPNFLCMEAPNNGSDDTSKGSHTQPPDSRPPRSGNSQELPVKERMGKDTCGNPGKFHFVQKSESCAPKCYSKVDVYWSHADKRFSLVWIAIWSILCFISSAFTVLTFLIDPQRFKYPERPIIFLSMSYCVYSVGYLIRLFVGAENVACDRD--SGVQYVIQEGLESTGCTIVFLILYYFGMASSLWWVILTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAIKTILILVMRRVAGDELTGVCYVGSMDVKALTGFVLIPLSCYLIIGTSFLLSGFVAL-FHIRKVMKTEGENTDKLEKLM---VRIGVFSVLYTVPATCVIACYFYERLNMDYWKVLAGEQRCLEGGGGEECMMKSSIPAVEIFMVKIFMLLVVGITSGMWIWTSKTLQSWQNVF 481          

Query:  151 KPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQ-----RKIQIQNLSLNKDRNNIHEPKQYRGQCRHMR-----NGEKYVFINR--TG---RCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA---PIKFSKRKDAI---VAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            +PI +  C+   YN T +    + D + EV + +  +  L+   CS  L F LCS+Y P C  D    L PCR VCE+ +  C P++      WPE+++C + P+       CM  +  E         K   +  S ++  +    P++   +CR          E +   NR  TG    CAL C +  +FS++ +     W+ + + L FVSTL T  TF  +  R +YPE+PIIFL   Y   S+  ++RL  G EKV+C       Q+ ++ +      C + FLL +FF  A+ +WW++L   W L   +     ++A  S  FHL  WL+ SV +++VL L SVD D + G+C VG Q+ + L  F + P ++ L  G +FLL+GF    +R +    +      K+  L+    R+GLF+++Y +    ++ C +Y+ +    W +A        +++  +    AVF+LK+FM  VVGI S +WI S  ++ +W++
Sbjct:   38 EPITVPMCKGIGYNLTYMPNQFNHDTQEEVGLEVHQFWPLVRIRCSPDLLFFLCSMYTPICLPDYKKPLPPCRSVCERAKRGCSPLMIQYGFEWPERMSCEQLPMLGDPDRLCMDQNSSETTTLSPSFPKPTPRGSSRHRATSKSAVPQKCDRECRCREPLVPIKKESHPLYNRVQTGSLPNCALPCHQ-PYFSQDERAFTTFWIGLWSVLCFVSTLTTVATFLIDMERFKYPERPIIFLAACYLFVSLGYIVRLLAGHEKVACGGS--GDQRHILYDTTGPALCTLVFLLIYFFGMASSIWWVVLSFTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLESLRGFVLAPLVVYLFSGSLFLLAGFVSL-FRIRSVIKQGGTKTDKLEKLM---IRIGLFTVLYTVPATIVVACLVYEQHYRPEWEQALGCSCASERQQQGLGPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRR 535          

Query:  157 IAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNL----SLNKDRNNI--------------HEPKQYRGQCRHMR---NGEKYVFINR--TG---RCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKD------------AIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            I +  C+   YN T +    + D + E  + +  +  L+   CS  L F LCS+Y P C  D    L PCR VCE+ +  C P+++    +WP+++ C R P+       CM  ++ +   +  +++      S N  +N                 E  +    CR        +++   NR  TG    CA+ C  + +F+++ +T A  W+ + + L FVST  T VTF  +  R +YPE+PIIFL+  Y   S+  ++RL +G + V C+ +     + +  E      C + FLL +FF  A+ +WW++L L W +   +  S+ ++A  S  +HL  WL+ SV +V+VL   SVDAD L G+CSVG Q+ + L  F ++P  + L +G +FLL+GF            +      K+  L+    R+G+FS++Y +    ++ C  Y+  +   W+RA I  S + D                +F+LK+FM  VVGI S +WI S  +V  WK+
Sbjct:   12 ITVPMCRGIGYNHTYMPNDFNHDSQDEAGLEVHQFWPLVEIKCSPDLRFFLCSMYTPICLEDYKQPLPPCRSVCERARAGCAPLMRQYGFAWPDRMRCDRLPVLGDQNRLCMDYNKSDTTPQPPEVKPTAPVRSFNPSKNRATTRVGGGGGGGGGSGEACESGCACRAPMVAIGSDRHPLYNRVRTGSVLNCAMPC-HDPYFTQDERTFASFWIGLWSILCFVSTFTTVVTFLIDMERFKYPERPIIFLSACYAFVSMGYIVRLVVGHDGVICNQE----HRHVHYETTGPALCTVVFLLTYFFGMASSIWWVILSLTWFMAAGMKWSSEAIAGYSQYYHLAAWLLPSVQSVAVLATSSVDADPLAGICSVGAQSLENLRGFVLVPLTVYLCVGAVFLLAGFTSLVRIRNAIKQQGGTKTDKLEKLM---VRIGIFSMLYTVPAIAVVACYFYEERSRDGWARALICPSCQGDEEPGSQQQQQQRPDYGIFMLKYFMCLVVGITSGVWIWSGKTVDTWKR 523          

Query:  151 KPIAIGQCQNKFYNFTS----LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRG---------------------------QCRHMRNGEKYVFINRTGR--CALKCSEND-----FFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAI-------------VAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEK 1611
            +PI+I  C +  YN T     L    + +  + +  +  L+   CS  L F LCS+Y P C       + PCR +CE+ +  CE ++      WPE+L C  FP++ S  + C+  +  +         +       ++   P  YR                             C H+     Y+     G+  C   C  +      +F  +    A +W+ V + L   STLFT +T+  +  R RYPE+PIIFL+  Y + SI+ ++  F   EK+ C+         ++Q G +   C I F++ +FFS A+ +WW++L L W L   +     ++  NS  FHL  W + ++ T+++L +  VD D L G+C VG  + D L  F + P  + L IG  FLL+GF    +R +          +K+  L+    R+G+FS++Y +    +I C  Y+      W ++ +  + +  A+               VF++K+ M  +VGI S  WI S  ++ +W+  +  L  K
Sbjct:   58 QPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPDLKFFLCSMYAPVCTVLEE-AIPPCRSLCERARQGCETLMNKFGFQWPERLRCENFPVQGSENI-CVGQNHTDEKGGHPTPPDPHPIPHGDSFTLPPHYRPGGPSSGGGIGGGGGGGASGGDSSSYQLTCPHVLRVPSYLNYQFLGKKECGSPCEPSKSNGLMYFDADELWFARMWVGVWSILCCASTLFTVLTYLVDMERFRYPERPIIFLSGCYAVVSIAYIVGFFF-EEKIVCNKFFEDSYSTVVQ-GTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILAMGQVDGDVLTGVCFVGLNSIDALRGFVLAPLFVYLFIGTSFLLAGFVSL-FRIRTIMKHDGTKTEKLEKLM---VRIGIFSVLYTVPATIVIACYFYEQAFRAQWEKSWVAHTCKSFAVQCPQGHYPNMKPDFTVFMIKYLMTLIVGITSGFWIWSGKTLQSWRNFYSRLSNK 588          

Query:  151 KPIAIGQCQNKFYNFTS----LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQM-----------QCMHPSQEENLQRKIQIQNLSLNKDRNNIH----EPKQYRGQCRHMRNGEKYVFIN--RTGRCALKCSEND-----FFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAI-------------VAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVML 1602
            +PI+I  C +  YN T     L    + +  + +  +  L+   CS  L F LCS+Y P C       + PCR +C++ +  CE ++      WPE+L C  FP++ S ++               P         +         D   IH      + +   C  +     Y+     R   CA  C         +FS+E    + +W+ + + L   STLFT  T+  + +R RYPE+PIIFL+  Y + +++ +   FL  +KV C+          + +G +   C I F+L +FFS A+ +WW++L L W L   +     ++  NS  FHL  W + +V T+++L +  VD D L G+C VG  +   L  F + P  + L +G  FLL+GF    +R +          +K+  L+    R+G+FS++Y +    +I C  Y+      W +  +  S +  AI               VF++K+ M  +VGI S  WI S  ++ +W+K +  L
Sbjct:   14 QPISIPLCTDIPYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPDLKFFLCSMYAPVCTVLEK-AIPPCRSLCDRARQGCEALMNKFGFQWPERLRCENFPVQGSDEICVGQNHTDKAGPTALPPTPPGGGGGVIGGIGGGAGDFVTIHTRRPPGRTHPFMCPRVLKVPPYLNAQLFRERNCAAPCEPKKPNGLMYFSEEELRFSRLWVGIWSVLCCASTLFTVTTYLVDMQRFRYPERPIIFLSGCYFMVAVAYVAG-FLLDDKVVCNEQFSEDIYRTVTQGTKKEGCTILFMLIYFFSMASSIWWVVLALTWFLAAGMKWGHEAIEANSQYFHLAAWAIPAVKTITILAMGLVDGDMLSGVCFVGISSVAALRGFVLAPLFVYLFLGTSFLLAGFVSL-FRIRTIMKHDGTKTEKLEKLM---VRIGIFSVLYTVPATIVIACYFYEQAFREQWEKTWVSQSCKGFAIPCPLNHYPNMKPDFTVFMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTKL 531          

Query:  628 RTGR---CALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXX-XXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPI------------KFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            RTG+   CA  C  + F  +E +T A  W+ + +SL F +T  T  TF  +  R +YPE+PIIFL+    + S+  ++R+  G E V+C  D       ++        C   FLL +FF  A  +WW++L L W +   L   + ++A  S  +HL  WL+ S+  ++ L + +VD D + G+CSVG Q+ D L  F + P +  L++G    L      F+ R    +N      +K+  L+    R+G+F+++Y +  A  + C LY+  +   W R  +            +   R D   AVF+LK+F+  V GI S  WI S  +  +WK+
Sbjct:   26 RTGQVRNCATPC-HSPFLGREQRTFASFWIGLWSSLCFAATFATVSTFLIDMERFKYPERPIIFLSLCCMLASLGYIVRMVAGHEAVACSAD----WHHVLYASSGPALCTAVFLLTYFFGMAGCVWWVILSLTWFMAAGLKWGSEAIAGYSQYYHLAAWLLPSIKAIAALAMNAVDGDPVAGICSVGNQSLDNLRGFVLAPLVAYLLVGTAFLLAGLVALFRIRNAISANPGGAKTEKLERLM---VRIGVFAVLYTVPAAVAVVCHLYEQQHRDSWERTLVCGACGPGPGHLPEPGARPD--FAVFMLKYFVCLVGGITSGAWIWSGKTAGSWKR 352          

Query:  136 EKC-KP---KPIAIGQCQNKFYNFTS----LSQDQEA--EVQIPIETYRSLLS-NGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNC--SRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN--RRIRYPEQPIIFLTFSYNIYSISILLR-LFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTL-FCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA 1455
            E+C +P   +P+A   C      +      L+ D  +  + Q  ++ +  L S   C + +  LLC+VY+P C    G    P R +C   +  C  + +  +  WP+ L+C   RFP    + +Q +H +   +    +                          +R      ++     C L CS +  ++ E           + +L  +S +FT  TF  +  R  RYP   I ++   + + S   L + L   R+ ++C  D     ++      E  +C I F+L ++   A   W++ L   W   F AL      LA+ +  FHL  W +  VLTV++L L+ VD D + G+C VG + P     F + P +    +   + L+   F  +R ++ S+  L   +  T +     RLG+F ++    +     C +Y + +   W R+
Sbjct:    1 ERCVRPAACEPLAYSSCLGAALPYAQTALVLASDSHSQHDAQANLQLWAGLRSVPRCWEVVQPLLCAVYMPRCS--AGAVELPSRALCHATRAPCAVVARTPH-GWPDFLSCQPERFPDGCPNTVQGVHFNTTSSCAAPL--------------------------VRTDNPASWVRDVEGCGLPCS-SPLYTAEEHAAMRTATAAMGALALLSEIFTLATFVGDWQRSRRYPAVVICYINACFLVASAGWLAQFLSDARQDITCRHD--GTPRVGEPTSSETLSCVIIFVLIYYPLMAAVCWFVCLAYAWNASFRALGTPQRPLARKTSYFHLACWSLPFVLTVAILALQQVDGDSMSGVCFVGYRDPHFRAGFVLAP-VGVATVAGGYYLACGMFTLFRIRR-SHPGLLSQKASTKIQETIVRLGVFGVLAWGFVLLTFGCHIYDFLHREQWQRS 423          

Query:  157 IAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSK-HLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSL-TFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVA-----VFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQLNSTNSN 1689
            I+I  C++  YN T +      + + E +  ++ +  L+  GC++  L F LCS Y P C     + +  CR +CE V+  C P+L    + WP  LNC+RF + ++ +  CM          K +     +N        P     QCR  +N + Y ++  T  CA++C+E+  F    K   +IW+ + +      +T+          R +YPE+ II+L   YN YS+S ++RL  GR+ +SCD DP +  K  IQ+GL NT CAI FL+ +FF  A  +WW++L L W L   +     ++   + +FH+  W++  + T+ +LI R VD DEL GLC VG Q    L  F + PQ   LIIG +FL++GF    +R +    +      K   L  +  R+G+FS++  +    +I C  Y+Y N  YW      +  ++D  VA     +F+LK FM+   G+ + +WI S  ++  W+  +        +    K   R++E  G  N+  + 
Sbjct:    7 ISIDLCRSVGYNVTRMPNLIGHETQKEAESQLKQFLPLIQYGCAREQLVFFLCSAYAPMCTDKVDVVITSCRPLCEYVRKSCLPVLTEFGIPWPNPLNCTRFLVRNNERNMCMPGPNFTESPEKPRPDFKPINDTTEK--PPSTGSEQCRRFKNSKNYFYVQSTESCAVRCNEDGIFKTSDKETMDIWITIWSIFCFISTTITLTTFLIETGRFKYPERSIIWLALCYNFYSLSYIIRLGAGRQAISCDTDPTTHVKFHIQDGLRNTGCAIVFLIQYFFCMAATIWWVVLALTWFLAAGMKWGCEAIGSYAKLFHIIAWILPCIKTIFILITRKVDGDELTGLCFVGNQDLIALAAFVLGPQFTYLIIGTLFLIAGFVAL-FRIRTTVQRG--GQAKTDKLERLIVRIGIFSVLSTVPATAVIACYFYEYANKEYW------YYGQRDGAVAEPNFSIFMLKVFMSLFTGVITGMWIWSHKTMNTWRAFY--------YKVSGKRPPRKLERNGNGNTNETT 509          

Query:   97 LFLLISIV-----DSIENEKCKPKPI----AIGQCQNKFYNFTSLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQ------CMH--------PSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFC-HNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGL---ENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWS-RAPIK-FSKRKDAI--------VAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQLNSTNSNKYWLYCKSGN*K*TEPHCNIFHPVLKS 1770
            LF+ +S +       + N KC P  I     IG    +F NF  L+Q+ + E    I  ++ L++  C+  L F LCSV+VP C  +  + +  CR +CE  +  C P+++    +WP+ L+C R P +   Q +      CM         P  E ++    +       K  N         G  R+     KY ++ +  +C  +C  +  FS  +K  A +W+ V + L F+ST  T +TF     R +YPE+PIIFL+  YN+YS+  ++R+  GR +V CD      +  +I+ G+   ++  C++ FLL ++F  A+ +WW++L   W L         ++ + +  FH   W + ++ T+  LI+R VDADEL GLC VG    + L  + + P  + L++G  FLL+GF    +R +        +  K+  L+    R+G+FS++Y I ++ +I C  Y+Y N   W  RAP   +  R D          + VF++K+FM  ++GI S +WI S  +  +W+K          ++K+    +++   Y   ++   N   ++    + +    H + F P+  S
Sbjct:   12 LFITVSAMVYGQRSEVPNSKCTPITIPLCMGIGYNATRFPNF--LAQESQEEAAKRIHEFKPLIAVNCAPLLRFFLCSVFVPMCTKEVNVPIYACRSMCESARDGCSPMMQRFGFNWPDTLDCDRLPKKGDPQAKSDPTKLCMAAPNIKQTAPLNESDIWSNFESLGPEFKKINNT--------GPLRY-----KYTYVEKYDQCVPQCKSDLMFSSNNKRFANVWISVWSVLCFISTAVTVLTFVIDTSRFKYPERPIIFLSLCYNLYSLGYIVRVTAGRNEVICD----ETESFVIRAGMNIADHACCSVVFLLLYYFGMASAVWWVVLTFAWFLAAGRKWGQEAIERKATYFHAVAWTVPAIQTIMALIMRKVDADELTGLCYVGNMDYENLANYVLTPLCLYLLVGTFFLLAGFVSL-FRIRTVLKNKETNTDKLEKLI---VRIGVFSVLYTIPVSAVIACSFYEYNNMDVWKVRAPFNTYICRGDQACLENYGPSIEVFIVKYFMLLIIGITSNMWIWSTKTFKSWRK---------FYSKRKGGEAKKKVDYSAGSAPPKNSLQVHMPPPSVQPVYHHTSAFAPIAPS 574          

Query:  106 LISIVDSIENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCM-HPSQEENLQRKIQIQNLSLNKDRNNIH------EPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSK----RKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
             IS ++ +  ++ K + I I  C+   YN T +    + D +AE  + +  +  L+   CS  L F LCS+Y P C+      L PCR VCE+ +  C P+++    SWPE++ C  FP        CM   S  E+  +  Q    + + D   I        P       ++++   + + +    +CA+ C+   +F+ +  + A  W+ +   L F+STL T +TF  +  R +YPE+PIIFL+  Y + S+  ++RL  G ++++CD        ++  +     +C I FLL +FF  A+ +WW++L   W L   +  S+ ++   S  FH   WL+ ++  ++VL + ++D D + G+C VG      L+ F I+P ++ L+ G  FL++GF+      K           K+  L+    R+G+FS++Y +    ++ C  Y+  N   W R  I  S     R     +VF++K+FM  VVGI S  WI S  ++ +W+
Sbjct:   15 FISCLNYVLTKEMKCEEITIPMCRGIGYNLTYMPNMFNHDTQAEAALEVHQFWPLVEIQCSPDLRFFLCSMYAPLCEKHYDKDLPPCRSVCERARTGCAPLMRKYGFSWPERMKCENFPELGDENTLCMGRNSSGESTPKPSQSPQPAPSPDTAAISANCCSCRPPFVSIAGKNIKP-TRAISVGGVPQCAMACNRT-YFTHDQDSFASFWIGLWAILCFISTLVTTLTFLVDMHRFKYPERPIIFLSGCYLMVSVGYIIRLIAGHKQIACD-----SNGLMRYDTSGPASCTIVFLLVYFFGMASSVWWVILAFTWFLSAGMKWSSEAITNYSQYFHAVAWLVPAIQAIAVLAMSTIDGDPVSGICYVGNHNLQSLVVFVIVPLVVYLVFGTSFLMAGFYSLVRIRKLLRQHGSTKTDKLEKLM---IRIGVFSVLYTVPATIVVACYYYELVNRETWERT-INCSGCGVTRVKPDHSVFIIKYFMALVVGITSGFWIWSGKTIESWR 512          

Query:  151 KPIAIGQCQNKFYNFT----SLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRN--GEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIV------------------------AVFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            +P+ I  C    YN T    +L    + E  + +  +  L+   CSK L F LCSVY P C       L PCR +C  V+  CE ++K    +WP+ L+C RFP        C+     EN       Q+  +N +     +    R +C   +    ++Y F +   RCA  C  N FF+K  + IA +W  +   L  VSTLFT +TF  + RR RYPE+PIIFL+  Y + SI+ +     G +K++C+     G    + +G ++  C + F++ +FFS A+ +WW++L + W L   L     ++  NS  FHL  W + +V T+++L++  VD DEL G+C VG      L  + + P  +  IIG  FLL+GF    +R +          +KI  L+    R+G+FSI+Y +    +I C  Y+  N   W  + I+  KR+                             VF++K+ M  +VGI S  WI S  ++ +W++
Sbjct:   30 EPVTIPLCTGLQYNMTIFPNTLKHRTQEEAALEVHQFFPLVKVDCSKDLAFFLCSVYAPVCTV-LETPLPPCRSLCLTVRSGCEGLMKRFGFTWPDSLSCERFPKLGDEI--CVG----ENTTTPTSDQDGGINNNTYPDVDMSTMRYRCPESQKIPNDQYTF-HGEKRCAATC-RNVFFTKREREIARMWTGIWAILCAVSTLFTILTFLIDMRRFRYPERPIIFLSGCYFMVSIAFITGYVAG-DKIACNEPIKKGFPKTLVQGTKHEGCTVIFMMLYFFSMASSIWWVILTVTWFLAAGLKWGQEAIEANSQFFHLAAWAIPAVKTIAILLMTKVDGDELSGVCYVGLSDVSALRGYVLAPLFVYFIIGATFLLAGFISL-FRVRSVLKDDYSKREKIEKLM---IRIGVFSILYTVPALVVIGCLYYEQSNRELWDNSWIEGWKRQKKCTEVETKLKGEVSCPPYPVPLQKPDFMVFMVKYLMFLIVGITSGFWIWSSKTLNSWRR 525          

Query:  139 KCKP--KPIAIGQCQNKFYNFTSLSQDQEAEVQIP--IETYRSL-LSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDR------NNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRI--RYPEQPIIFLTFSYNIYSISILLRLFL-GREKVSCDFDPVSGQKILIQEGLENTN--CAITFLLNFFFSTATHMWWIMLCLCWTL-FCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA 1455
            KC+P  +   +G+  +  Y  T L  D  ++ Q+   +E +  L     C + L   LC +Y P C  +  ++L PCR+ C   +  C  +       WPE L C + P              E N      ++ L LN+           ++P  Y G                   C ++C  N  FS+E  T    ++    +LT V TLFT VTF    +   RYP   + F+   + + S+  L++     R KV C  D      + + E  E+ +  C +TF+L ++FS A   W++ML   W + F  L  +  + A  +G FH+  W + +VLT  VL+++ VDA+ + G+C VG + P +   F + P  + L+IG +FL  G F   ++ +K +   L +   I    +I  R+G F+ +    +     C +Y+YYN   W R+
Sbjct:   25 KCEPLKEQTCLGEKLDYHYTTTELVTDSSSQDQVKKNLEKWEGLKFLPKCWEVLQPFLCQIYKPKCK-NGSVEL-PCREQCFATRKPCSVVESYRR--WPEFLRCDKLP--------------EGNCNG--TLKKLHLNESACKAPLVETAYKPSWYEG----------------IEGCGIQCM-NPIFSEEEHTRIHRFVAAFGTLTTVCTLFTVVTFLVGWKSQNRYPSVILFFMNACFCVASVGFLIQFSSDARRKVVCRRD----DTMRLGEPTESDSFLCVLTFVLVYYFSLAGMTWFVMLAYSWCICFKTLGSTRDNFAGKTGYFHIISWSLPAVLTGCVLLVKQVDANSISGICFVGYKNPSMRAGFLLAPLGLDLVIGGMFLAKGLFTL-FKLRKSNPNFLSNRASIKIKETI-MRVGFFAFVAFAFVFITFACHVYEYYNQERWERS 437          

Query:  121 DSIENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCS-ENDFFSKESKTIAEIWMKVITSL-TFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSRE 1650
            D +E   C P  I I  CQ   YN T +        +++ ++ + T+  L+  GCS  L F LCSVYVP C     I + PC  +C  V+  C P+L     +WPE LNCSRFP ++ H   CM    +E+                 ++H P     Q       ++Y ++ +T  C L+C  +N  + + +K   + WM V   L    +TL        ++R  YPE+PIIFL+   N+YS++ L+RL LGRE+VSCD D V G  +L+QEGL++T CAI FLL +FF  A+ +WW++L L W L   L     ++  +S  FH+  W + +  T+ +LI+R VDAD+L GLC VG Q  + L  F + P    L++G +F+ +G     ++ +    K      K+  L+    ++G+FSI+Y +  +T+I C LYQ  ++  +       +   D+ V   +L+ FM+ +VGI S +WI S  ++  W++C   LL +    +  KS   E
Sbjct:   28 DEMEEMTCDP--IRISMCQGLGYNVTKMPNLVGNMLQSDAELQLTTFTPLIQCGCSSQLKFFLCSVYVPMCTDKVPIPIGPCGSMCLSVKRKCLPVLLEFGYTWPEALNCSRFPPQNDHNHMCMEGPGDED-------------PPYQSVHHPSDQDCQALD-STPDQYTWLKQTESCVLQCGYDNGLYRRGAKVFTDAWMAVWAVLCFLSTTLTVLTFLLDSQRFSYPERPIIFLSMCCNLYSVAYLVRLTLGRERVSCDLDAV-GVPVLVQEGLKSTGCAIVFLLLYFFGMASSLWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAAKTIVILIMRLVDADDLTGLCYVGNQQQEALTGFVVAPLATYLLVGTLFICAGLMAL-FKIRSNLQKDGTKTDKLERLM---VKIGVFSILYTVPASTVIGCYLYQLSHWGEFK------TSTHDSYVTSEMLRIFMSLLVGITSGMWIWSAKTLHTWQRCSSRLLREGHVGRGGKSAPGE 516          

Query:  109 ISIVDSIENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMH-PSQEENLQRKI-QIQNLSLNKDR----NNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSE--NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYW------------SRAPIKFSKRKDAIVA--VFLLKFFMNQVVGINSAIWILSLDSVAAWKKCF 1593
            IS +D   + + + + I I  C++  YN T +      D + E  I ++ + SL+  GC  HL F LCS+Y P C       +  CR +CE+V+  C PIL+     WP+ L+CSR P ++     CM  P+   +   K+   Q       +     ++H PK   G+ +   N  K+ F+ ++  CA KC    + F+S+  K  + +WM + + L FVS+ FT +TF  + +R +YPE+PIIFL+ SY +YS+  L+RLF+G + ++CD D  +G + +IQEGLE+T C I FL+ ++F  A+ +WW++L L W L         ++  NS  FHL  W + +V T+ +L++R V  DEL G+C VG      L  F +IP    LIIG  FLLSGF    +  +K       +  K+  L+    R+G+FS++Y +    +I C  Y+  N  YW            SR        K +I A  +F++K FM  VVGI S +WI +  ++ +W+  F
Sbjct:   19 ISSIDPDWSGEGRCQHITIPLCKDIGYNMTRMPNLMGHDDQLEAAIKLQEFASLIQCGCHSHLKFFLCSLYAPMCTEQVSNPIPACRVMCEQVKVKCSPILEKFQFPWPDSLDCSRLPTKNDPNNLCMEAPNNSSDEPPKVPHTQPPDFRPQQPLSGQDLH-PKDI-GEKQTCSNPGKFHFVEKSESCAPKCYPKVDVFWSQGDKQFSLVWMAIWSILCFVSSAFTVLTFLIDPQRFKYPERPIIFLSMSYCVYSVGYLIRLFVGADGIACDRD--NGVQYIIQEGLESTGCTIVFLILYYFGMASSLWWVILTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTIMILVMRKVAGDELTGVCYVGSMDVKALTGFVLIPLSCYLIIGTSFLLSGFVAL-FHIRKVMKTEGENTDKLEKLM---VRIGVFSVLYTVPATCVIACYFYERLNMDYWRILAWKQKCVDGSRPESDECVMKASIPAIEIFMVKIFMLLVVGITSGMWIWTSKTLQSWQNVF 532          

Query:  103 LLISIVDSIENEKCKPKPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLN------KDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSE--NDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFC-HNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIK-----FSKRKD--------AIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKK 1629
            L +S  D   +   K +PI I  C    YN T +      D +AE  I ++ +  L+  GC  HL F LCS+Y P C       +  CR +CE+ +  C PI+K  + +WP+ L+CS+ P  +     CM   + E      + +           + R       +  G      N +K+ F+ ++  CA +CS   + ++S++ K  A IWM V + L FVST FT +TF     R +YPE+PIIFL+  Y +YS++ ++R   G E ++CD +   G+  +IQEGLE+T C I FL+ ++F  A+ +WW++L L W L         ++  +S  FH+  W + ++ T+ +L +R V  DEL GLC VG      L  F +IP    LIIG  F+L+GF    +  +K       + +K+  L+    ++G++SI+Y +    +I C  Y+  N  YW    ++     FS              VAVF+LK FM+ VVGI S +W+ S  ++  W+      L   T ++K
Sbjct:   26 LEMSFYDLERDRPAKCEPIVIPMCVGIGYNLTRMPNFMDHDDQAEAAIKLQEFAPLVDYGCDVHLRFFLCSLYAPMCTDKVSTSIPACRPMCEQARDKCAPIMKKFSYTWPDSLDCSKLPTRNDPNALCMEAPENETRTEGKKDKKKGEGMLPVPPRPRQPDTPSSRLPGSGNSCENPDKFQFVEKSQSCAPRCSPAVDVYWSRQDKDFAFIWMTVWSILCFVSTAFTVLTFLLEPHRFQYPERPIIFLSMCYMVYSLAFIIRSVAGAENIACDRE--HGELYIIQEGLESTGCTIVFLILYYFGMASSIWWVILTLTWFLAAGKKWGHEAIEAHSNYFHMAAWGIPALKTIVILTMRKVAGDELTGLCYVGSMDSGALTGFVLIPLSCYLIIGTSFILTGFVAL-FHIRKVMKTEGTNTEKLEKLM---VKIGIYSILYTVPATCVIVCYFYERLNMDYWKLRGLQEECDSFSSHNSKCSLETSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQGLCSRKLSDRTSSRK 554          

Query:  151 KPIAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNG------EKYVFINR--TG---RCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA-----PIKFSKR-KDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKK 1587
            +PI +  C+   YN T +    + D + EV + +  +  L+   CS  L F LCS+Y P C  D    L PCR VCE+ +  C P++      WPE+++C   P +   +  CM  +  E           S  K R     P Q   +CR  R+       E +    R  TG    CAL C    +FS + +     W+ + + L F+STL T  TF  +  R +YPE+PIIFL   Y   S+  ++RL  G E+V+C     S   IL  +      C + FLL +FF  A+ +WW++L   W L   +   + ++A  S  FHL  WL+ SV ++ VL L SVD D + G+C VG Q+ + L  F + P ++ L  G +FLL+GF    +R +    +      K+  L+    R+GLF+++Y +    ++ C +Y+ +    W RA     P++  +  +    AVF+LK+FM  VVGI S +WI S  ++ +W+ 
Sbjct:   25 EPITVPMCKGIGYNLTYMPNKFNHDTQEEVGLEVHQFWPLVRIRCSPDLLFFLCSMYTPICLPDYRKPLPPCRSVCERAKRGCSPLMSQYGFEWPERMSCEGLP-QLGDETLCMDQNSSEATTSAPPFPK-STPKVRTRPPSPSQCDRECR-CRDPLIPIKRESHALFGRVQTGPLPNCALPC-HLPYFSADERAFTSFWVGLWSVLCFISTLTTVATFLIDMERFKYPERPIIFLAACYLFVSLGYIIRLVAGHERVACGAGGTSQLHIL-YDATGPALCTLVFLLVYFFGMASSIWWVVLSFTWFLAAGMKWGSEAIAGYSQYFHLAAWLIPSVKSILVLALSSVDGDPVAGICYVGNQSLENLRGFVLAPLVVYLFTGTLFLLAGFVSL-FRIRSIIKQGGTKTDKLERLM---IRIGLFTVLYTVPATIVVACLVYEQHYRPSWERALACSCPLERQRSIRGPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRS 516          

Query:  157 IAIGQCQNKFYNFTSL----SQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEEN------LQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNG------------EKYVFINR--TGR---CALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHN-RRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSC--DFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAP-------IKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            IA+  C+   YN+T +    + D + E  + +  +  L+   CS  L F LCS+Y P C  D    L PCR VCE+ +  C P+++     WP+++ C   P++ +    CM  ++ ++      L +       S          P +Y+        G            E++   NR  TG+   CA+ C  N +F+ + +     W+ + + L FVST  T  TF  +  R +YPE+PIIFL+  Y   S+  ++RL  G EKV+C  DFD     + +  E      C I FLL +FF  A+ +WW++L L W L   +     ++A  +  FHL  WL+ S+ +++VL L SVD D + G+C VG Q  D L  F + P +I L IG +FLL+GF    +R +    +      K+  L+    R+G+F+++Y +    ++ C  Y+ +N   W            +   R     AVF+LK+FM  +VGI S +WI S  ++ +W+
Sbjct:   24 IAVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERARAGCAPLMRQYGFPWPDRMRCDLLPVQGNPDTLCMDYNRNDSTTASPVLSKPTNHPGRSPKSKPGRAGAPGKYKPPAAPCEPGCRCLEPMVAVTTERHPLYNRVKTGQVTNCAMPC-HNPYFTHDERAFTAFWIGLWSVLCFVSTFATVATFLIDMERFKYPERPIIFLSACYMFVSVGYIVRLIAGHEKVACNRDFD----VEHIHYETTGPALCTIVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIASYAQHFHLAAWLIPSMKSIAVLALSSVDGDSVAGICYVGNQNLDNLRGFVLAPLVIYLFIGTMFLLAGFVSL-FRIRSVIKQGGTKTDKLEKLM---IRIGIFTVLYTVPATVIVACYFYEQHNRQDWEMTHNCSSCLMERERARSGPDYAVFMLKYFMCLLVGITSGVWIWSGKTLDSWR 527          

Query:   67 MIKLPPVNICLFLLISIVDSIENEKCKPKPIAIGQCQNKFYNFTSLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQLNSTNSNKYWLYCKSGN 1719
            MIKLPPVNICLFLLISIVDSIENEKCKPKPIAIGQCQNKFYNFTSLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHE KQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSA+SLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQLICLIIGFIFLLSGFFFFKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSIIYIIAIATMICCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQLNSTNSNKYWLYCKSGN
Sbjct:    1 MIKLPPVNICLFLLISIVDSIENEKCKPKPIAIGQCQNKFYNFTSLSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHELKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSAMSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQLICLIIGFIFLLSGFFFFKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSIIYIIAIATMICCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIESYGQLNSTNSNKYWLYCKSGN 551          

Query:   85 VNICLFLLISIVDSIENEKCKPKPIAIGQCQNKFYNFTS----LSQDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKS---LCHHQKITFLLSIG---FRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKVTFNKKIKSNSREIES 1659
            +++C+ LL   + S  N KC  +      C+N F++ +S    +++D   + +I I+TY+S  ++ C K L  LLC +  P CD  T I+L PCRK CEKVQFDCEPILKLVNLSWPEKLNCSRFPL++SHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHE KQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLL FSIIP++ CL++G  FL  G      R+ K S K     C +Q+   L+ +     R+  F  IY + I+  ICC+ YQ+ NY  W             I  V+LLK F+NQVVGI SAIW LSLDS  AW + F  + +K    KK   NS+  +S
Sbjct:    8 ISLCIILLQ--IHSYTNRKCTKESKKHFYCRNDFFDLSSSKELIAEDYLLKFKIQIKTYKSFQNHKCIKTLITLLCLIQDPLCDPITNIRLGPCRKACEKVQFDCEPILKLVNLSWPEKLNCSRFPLKNSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHELKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNRRIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLLFSIIPKISCLVLGLTFLTIGLAIHAGRSDKLSGKVQILTCLNQQSEQLMDLSPMKLRIKTFLFIYCVTISLSICCDAYQFNNYASWLVNNPNTLNLTFPIFTVYLLKMFVNQVVGIYSAIWFLSLDSRGAWVELFRKITKKWDSEKKTSPNSQHFKS 540          

Query:  115 IVDSIENEKCKPKPIAIGQCQNKFYNFTSLSQ----DQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNR-RIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENTNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWK 1584
            +++ ++  KC PK I + +CQN FYNFT +      + + E Q  ++T++SL+   CS++L F LCSVY+P CD  +   + PC+ +CE+V+  CE I++  NL WP  LNCSRFP+ ++    CM                        ++   + ++  C  M+N   ++FINRT +C  KCS N  F+ + K IA+IW+ V+ SL F+S++FT +TF  N  R +YPE+P+IFL   Y+IYS+S  + L   R+  +C+ DPVSGQ IL QEGL+NT CAI FLLNFFFSTA+ +WW++L + W L      S  ++ + SG FHL  WL++S+LTV+VL+LRSVDADEL GLCSVG+Q    LL F +I   I  +I   F L G      R ++         +K+  L+    R+GLFS+++++  +T++ C  Y+Y N  +W ++        +  + V++LK FM+ VVGI S +W+ S+ ++ +W+
Sbjct:   37 VLEPVQTRKCLPKKILVPECQNLFYNFTGMPNLVNLETQIEAQSQLQTFQSLIKYKCSQNLLFFLCSVYIPMCDPISNYLIGPCQPLCEEVRDSCERIMRPFNLPWPVTLNCSRFPIRNAEGSMCMEGPGP-------------------SVKSTENFQTMCGGMKNPRLFIFINRTQKCVPKCSANILFTVDDKYIAKIWLTVLASLCFISSVFTILTFLINTDRFKYPERPVIFLAVCYSIYSVSHFINLANTRQSAACNRDPVSGQFILTQEGLDNTLCAIIFLLNFFFSTASQIWWVILTVAWLLAAGFKWSEEAIYQRSGYFHLAAWLISSLLTVAVLVLRSVDADELLGLCSVGQQNVSTLLIF-VIIPNIIFLIIGCFFLLGGLVALVRVRRHVKNDGIKTEKLEILM---VRIGLFSVLFLVPSSTVLGCNFYEYANRDHWLKS------GTNPNIEVYMLKIFMSSVVGITSGVWVWSIKTLESWQ 502          

Query:  124 SIENEKCKPK---PIAIGQCQNKFYNFTSLSQDQE----AEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCR-----HMRNGEKYVFINRTGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNR-RIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLENT-NCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRA---PIKFSKRKDAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLL 1605
            SI     +P    PI I  C+   YN T +  D       E  + I+ + +L+   CS+ L   LCS+Y P C  +   ++  CR +C   +  C  ++      WPE +NC + P +++    C+   +++N  R  +  N     +R  + + K+    CR       R+    V       C + C  + +F +  K+ +  W+ +   +  +ST  T +TFC ++ R +YPE+PIIFL+  Y + S+  L+R+ LG E V+C  D        I+ G      C+I FL  +FF  A+ +WW++L   W L   L   + ++   + I+H F W +  + ++ +L + SVD D + G+C VG      LL F IIP ++ L++G  FLL+GF       K    K      K+  L+    R+ +F I+Y +   T++ C +Y++     W ++   P + +K+     +VF+LK+FMN VVG  +  WI +  ++ +W K F  LL
Sbjct:   24 SISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNA----CL---RKDNKTRSNKTANFV--SERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNC-RSPYFGEFDKSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDA-------IRYGSSGAVPCSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYLLVGTGFLLAGFLALMKIRKTIKEKGESKTDKLEKLM---IRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTCPCR-TKKYQPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKLL 513          

Query:  118 VDSIENEKCKPK---PIAIGQCQNKFYNFTSLS----QDQEAEVQIPIETYRSLLSNGCSKHLNFLLCSVYVPFCDYDTGIQLEPCRKVCEKVQFDCEPILKLVNLSWPEKLNCSRFPLESSHQMQCMHPSQEENLQRKIQIQNLSLNKDRNNIHEPKQYRGQCRHMRNGEKYVFINR----------TGRCALKCSENDFFSKESKTIAEIWMKVITSLTFVSTLFTCVTFCHNR-RIRYPEQPIIFLTFSYNIYSISILLRLFLGREKVSCDFDPVSGQKILIQEGLEN-TNCAITFLLNFFFSTATHMWWIMLCLCWTLFCALNVSALSLAKNSGIFHLFVWLMTSVLTVSVLILRSVDADELFGLCSVGEQTPDLLLTFSIIPQXXXXXXXXXXXXXXXXXXKYRTKKFSNKSLCHHQKITFLLSIGFRLGLFSXXXXXXXXXXXCCELYQYYNYHYWSRAPIKFSKRK--------DAIVAVFLLKFFMNQVVGINSAIWILSLDSVAAWKKCFVMLLEKV 1614
             D    E  +P    PIAI  C+N  YN T +      + + E  + +  +  L+   CS +L   LCS+Y P C  +    ++ CR VCE  +  C P++      WP+ ++C +     +    C                   L KD  N+ +P     +C+       Y++ N+             C   C   +F S + K+    W+ +   L  +S+  T +TF  +R R +YPE+PI+FL+  Y + SI  ++R+ +G E ++CD D        ++ G      C+I FLL +FF  A  +WW++L + W L   L   + +++K S IFH   W ++ V ++  L L ++D D + G+C +G      L  F I+P  + L+IG  FLLSGF       K    K      K+  L+    R+G+F ++Y +  A +I C LY+  N  +W ++   +  R             +VF+LK+FM  VVGI S  WI +  ++ +W   F  L + +
Sbjct:   46 ADRSNQENFRPNKCVPIAIPMCKNIGYNLTYMPNEFHHETQEEAGLVVHQFYPLVEIACSDNLRLFLCSLYAPICLPNWPKPIQACRSVCESARDGCAPVMNTYGFKWPKSMDCDKL----TENQAC-------------------LKKDTKNVTKPPSKGCECKCR---SPYIYDNKPQFNSVITGGVANCFQSCHSANFVSID-KSFVTFWLGLWAVLCCLSSTATVLTFLLDRSRFKYPERPIVFLSGCYMMVSIGYIIRVAVGHELIACDGDK-------LRYGTTGPARCSIVFLLIYFFGMAASVWWVILTITWFLSAGLKWGSEAISKYSEIFHFLAWFLSGVKSILALTLVAIDGDPVGGICYIGNTNSLNLKLFLIVPLTVYLLIGSCFLLSGFIALISIRKTIRAKGESKTDKLEKLM---MRIGIFGLLYSVPAAVVIGCHLYEVKNREFWEKSNNCYCNRNIKSQENFSKPEYSVFMLKYFMCLVVGITSGFWIWTSKTLDSWHNAFRRLSQSI 534