Thyroid adenoma-associated-like protein

Overview
NameThyroid adenoma-associated-like protein
Smed IDSMED30023155
Length (bp)4372
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Thyroid adenoma-associated-like protein (SMED30023155) t-SNE clustered cells

Violin plots show distribution of expression levels for Thyroid adenoma-associated-like protein (SMED30023155) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Thyroid adenoma-associated-like protein (SMED30023155) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Thyroid adenoma-associated-like protein (SMED30023155) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30023155

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30023155h1SMcG0022363 SmedASXL_018272SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30023155h1SMcG0022363 SmedASXL_018272SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
pharynxSMED30023155h1SMcG0022363 dd_Smed_v4_12325_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30023155h1SMcG0022363 dd_Smed_v4_12325_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30023155h1SMcG0022363 dd_Smed_v4_12325_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30023155h1SMcG0022363 dd_Smed_v4_12325_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30023155h1SMcG0022363 dd_Smed_v4_12325_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30023155h1SMcG0022363 dd_Smed_v4_12325_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Human
Match: THADA (THADA armadillo repeat containing [Source:HGNC Symbol;Acc:HGNC:19217])

HSP 1 Score: 142.124 bits (357), Expect = 4.793e-33
Identity = 88/260 (33.85%), Postives = 144/260 (55.38%), Query Frame = 3 
Query: 1776 EYLTICCWRSCKEISLILGNI----AAELVNKSSDNF---NQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSL-NFAMDQLNSILVKADS-QNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIK 2519
            + + +CCWRS KE++L+LG +      + V +SSD      QV++I D+F   +    H+GAFE    GF KL + L R   + + ++P  ++   ++ I  ++    LC+TRRSAG+P     L+ SEP   K R  L    M +L S+    D  Q++  Q   +H  NI R LF+++ L   +I +     K ++  F+S +W +RNS+TLL+ ALI RIFG  +    H+K NR+  + FF+R+  +Y F++  ++
Sbjct: 1047 QMVLVCCWRSMKEVALLLGMLCQLLPMQPVPESSDGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQALLASEP--KKGRMDLLKITMKELISLAGPTDDIQSTVPQ---VHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSALITRIFGVKRAKDEHSKTNRMTGREFFSRFPELYPFLLKQLE 1301

HSP 2 Score: 58.151 bits (139), Expect = 1.455e-7
Identity = 80/346 (23.12%), Postives = 142/346 (41.04%), Query Frame = 3 
Query:  867 NVRMEMFAILCKEISRQNQRNYQLWNQILRFLIS-NLSIASNKLRQHFVNCFRQLV-----------------------NGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSF--DSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYE------SLKQIALEKSNTSNPHDCAVA-----FTIMKTLLGIEEYKLLPHVIA----DQLIARLE--------CSLESIKSNI-----ELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP 1727
             VR++   +LC E +R  +       Q ++F I+ NL+  S  +RQ   +  ++L                        N + +Q+   S      F++ +   L   L+P +S+  R S L +L  I   F    G I+ +  +S    V   +TL+  F  TFE+ ++ A   F +L+       H++       L Q ALE S ++ P+DC  A     F I +  L       L   +A    D+  A +E        C +E+++  +      L   A   P Y  ++C+   L +   N    +S     V +++ + Y ++ V+ P   S++PEG +P
Sbjct:  636 QVRIDTLGLLC-ESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQHPSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILA---FDLLMKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENLEEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIP 977
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Human
Match: THADA (THADA armadillo repeat containing [Source:HGNC Symbol;Acc:HGNC:19217])

HSP 1 Score: 142.124 bits (357), Expect = 4.793e-33
Identity = 88/260 (33.85%), Postives = 144/260 (55.38%), Query Frame = 3 
Query: 1776 EYLTICCWRSCKEISLILGNI----AAELVNKSSDNF---NQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSL-NFAMDQLNSILVKADS-QNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIK 2519
            + + +CCWRS KE++L+LG +      + V +SSD      QV++I D+F   +    H+GAFE    GF KL + L R   + + ++P  ++   ++ I  ++    LC+TRRSAG+P     L+ SEP   K R  L    M +L S+    D  Q++  Q   +H  NI R LF+++ L   +I +     K ++  F+S +W +RNS+TLL+ ALI RIFG  +    H+K NR+  + FF+R+  +Y F++  ++
Sbjct: 1047 QMVLVCCWRSMKEVALLLGMLCQLLPMQPVPESSDGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQALLASEP--KKGRMDLLKITMKELISLAGPTDDIQSTVPQ---VHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSALITRIFGVKRAKDEHSKTNRMTGREFFSRFPELYPFLLKQLE 1301

HSP 2 Score: 58.151 bits (139), Expect = 1.455e-7
Identity = 80/346 (23.12%), Postives = 142/346 (41.04%), Query Frame = 3 
Query:  867 NVRMEMFAILCKEISRQNQRNYQLWNQILRFLIS-NLSIASNKLRQHFVNCFRQLV-----------------------NGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSF--DSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYE------SLKQIALEKSNTSNPHDCAVA-----FTIMKTLLGIEEYKLLPHVIA----DQLIARLE--------CSLESIKSNI-----ELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP 1727
             VR++   +LC E +R  +       Q ++F I+ NL+  S  +RQ   +  ++L                        N + +Q+   S      F++ +   L   L+P +S+  R S L +L  I   F    G I+ +  +S    V   +TL+  F  TFE+ ++ A   F +L+       H++       L Q ALE S ++ P+DC  A     F I +  L       L   +A    D+  A +E        C +E+++  +      L   A   P Y  ++C+   L +   N    +S     V +++ + Y ++ V+ P   S++PEG +P
Sbjct:  636 QVRIDTLGLLC-ESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQHPSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILA---FDLLMKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENLEEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIP 977
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Human
Match: THADA (THADA armadillo repeat containing [Source:HGNC Symbol;Acc:HGNC:19217])

HSP 1 Score: 128.642 bits (322), Expect = 4.111e-29
Identity = 91/265 (34.34%), Postives = 140/265 (52.83%), Query Frame = 3 
Query: 1788 ICCWRSCKEISLILGNI----AAELVNKSSDNF---NQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSL-NFAMDQLNSILVKADS-QNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLN-SKVFFNRYQN--------MYEFIVNTIK 2519
            +CCWRS KE++L+LG +      + V +SSD      QV++I D+F   +    H+GAFE    GF KL + L R   + + ++P  ++   ++ I  ++    LC+TRRSAG+P     L+ SEP   K R  L    M +L S+    D  Q++  Q   +H  NI R LF+++ L   +I +     K ++  F+S +W +RNS+TLL+ ALI RIFG  +    H+K NR   S V+ +R           M + I NTI+
Sbjct:  365 VCCWRSMKEVALLLGMLCQLLPMQPVPESSDGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQALLASEP--KKGRMDLLKITMKELISLAGPTDDIQSTVPQ---VHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSALITRIFGVKRAKDEHSKTNRCGHSPVYHSREMAARALVPFVMIDHIPNTIR 624

HSP 2 Score: 57.3806 bits (137), Expect = 2.526e-7
Identity = 66/271 (24.35%), Postives = 116/271 (42.80%), Query Frame = 3 
Query: 1020 RQLVNGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSF--DSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYE------SLKQIALEKSNTSNPHDCAVA-----FTIMKTLLGIEEYKLLPHVIA----DQLIARLE--------CSLESIKSNI-----ELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP 1727
            R+  N + +Q+   S      F++ +   L   L+P +S+  R S L +L  I   F    G I+ +  +S    V   +TL+  F  TFE+ ++ A   F +L+       H++       L Q ALE S ++ P+DC  A     F I +  L       L   +A    D+  A +E        C +E+++  +      L   A   P Y  ++C+   L +   N    +S     V +++ + Y ++ V+ P   S++PEG +P
Sbjct:   24 REPENELTKQHPSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILA---FDLLMKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENLEEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIP 291
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Celegans
Match: Y92H12A.5 (pep chromosome:WBcel235:I:1490887:1514411:-1 gene:WBGene00022361.1 transcript:Y92H12A.5b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y92H12A.5)

HSP 1 Score: 141.739 bits (356), Expect = 1.852e-33
Identity = 93/320 (29.06%), Postives = 166/320 (51.88%), Query Frame = 3 
Query: 1662 CYAINDVIFPFNSSAAPEGCLPDEVRNLL---DSHFVESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNED---LCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFH---NKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYPILVILGRL 2594
            C+ I  ++ P   S  PEGC+PDE+ + L    +  +    ++L ICCWR+ K +S I   I   L         +++ I  F++ Q+T   H+GAFES   GF +LC  LW S+T++ +  P  ++ + +  I    D   LCSTRRSAGLP L L ++ +EP  N+     N A+ +    L+  D + S  +   +H  N+ + + + S+L  + +     A++ +++   ++ W  RN+A+ L+ AL  +IFG  ++ +     +  NR ++  FF+++  +Y+F+ + +    +S  +L       P LV+L  L
Sbjct:  645 CHKIIKIVAPVVQSMTPEGCIPDEILSKLCGVSADRLTEISQHLLICCWRAHKHVSGIFAWIIEMLAPLGIVTNAEIEAIGSFYWAQLTECKHRGAFESATDGFFQLCSFLW-STTIQGLPKPADWLEEILSAIRGETDLTNLCSTRRSAGLPSLVLSIVATEPKENE-----NGALIKATGSLLNMDGKTSEYR---VHSMNVMKTIVQSSTLHNKAVFCFERALRVAIEACRAD-WSERNAASQLFAALRTKIFGVMRSAQRSLVVDAKNRKSNYEFFSKFPTLYKFLYDQLTSEQQSEFSL------LPPLVVLSHL 948
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Celegans
Match: Y92H12A.5 (pep chromosome:WBcel235:I:1491340:1514411:-1 gene:WBGene00022361.1 transcript:Y92H12A.5a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y92H12A.5)

HSP 1 Score: 141.354 bits (355), Expect = 1.913e-33
Identity = 93/320 (29.06%), Postives = 166/320 (51.88%), Query Frame = 3 
Query: 1662 CYAINDVIFPFNSSAAPEGCLPDEVRNLL---DSHFVESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNED---LCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFH---NKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYPILVILGRL 2594
            C+ I  ++ P   S  PEGC+PDE+ + L    +  +    ++L ICCWR+ K +S I   I   L         +++ I  F++ Q+T   H+GAFES   GF +LC  LW S+T++ +  P  ++ + +  I    D   LCSTRRSAGLP L L ++ +EP  N+     N A+ +    L+  D + S  +   +H  N+ + + + S+L  + +     A++ +++   ++ W  RN+A+ L+ AL  +IFG  ++ +     +  NR ++  FF+++  +Y+F+ + +    +S  +L       P LV+L  L
Sbjct:  645 CHKIIKIVAPVVQSMTPEGCIPDEILSKLCGVSADRLTEISQHLLICCWRAHKHVSGIFAWIIEMLAPLGIVTNAEIEAIGSFYWAQLTECKHRGAFESATDGFFQLCSFLW-STTIQGLPKPADWLEEILSAIRGETDLTNLCSTRRSAGLPSLVLSIVATEPKENE-----NGALIKATGSLLNMDGKTSEYR---VHSMNVMKTIVQSSTLHNKAVFCFERALRVAIEACRAD-WSERNAASQLFAALRTKIFGVMRSAQRSLVVDAKNRKSNYEFFSKFPTLYKFLYDQLTSEQQSEFSL------LPPLVVLSHL 948
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Fly
Match: THADA (gene:FBgn0031077 transcript:FBtr0289978)

HSP 1 Score: 132.88 bits (333), Expect = 1.197e-30
Identity = 145/592 (24.49%), Postives = 270/592 (45.61%), Query Frame = 3 
Query: 1059 SSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFLKT--LVYFFADTFEENRMNASKCFIILVNTKPLVDHYES----LKQIALEKSNTSNPHDCAV-AFTIMKTLLGIEEYKLLP-----HVIADQLIAR-LECSLESIKSNIELFHIAMN-----SPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLPD--------EVRNLLDSHF-------VESHPEYLTICCWRSCKEISLILGNIAAELVNKSS-------------DNF----NQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNED-------LCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQ-FFSSNIWPLRNSATLLYCALIERIFGPSK----TIKFHNKFNRLNSKVFFNRYQNMYEFIVNTI-KECDKSPLNLNSS----------TRIYPILVILGRLVP 2600
            +SQ V  +FL +L+R L++NL+P A++ +R   L +        D   + +++ ++ +E  I L T  L+    D++E N++ A++          L++ ++S         +E   +  P D A  AF +            +P       I + L  R L+  L+ ++  + L  + +      +P Y  L+  R+LL +      ++       +  ++++C A++ V+ P  SSA+PEG LP+         + N+LD          V + P+ + +C WRS KE+ LILG    ELV ++               +F     Q++ I + F   +    H+GAFE    GF  LC+  W S ++ + ++P  ++ +++ ++   E+       LC+TRRSAG+P +   L+ +E L     ++L   M++L  +  +     +    R  H  NI R LF+ S L   +       ++ ++     +  W  RNSATLL  ALI R+FG  +    T + H + NR+  ++FF RY  ++++    + +E ++       S           ++  +L++L RL P
Sbjct:  640 ASQEV-LQFLIRLIRTLAQNLFPTANYGRRWLSLRL------LRDCLELSEMVGITFSELGIELPTEALMACLGDSYEHNKVLAAQ----------LLERFQSHSLFKPDEMIELLLSLRPSDSATGAFQLQVYCKASRVQSEMPTPTHGGTIHEPLTFRALQWCLQHLREGLRLAQLDLGEAAKLNPLYGLLFASRHLLQQLKLKELAKEPQWRQYIDELVTMCLAVSSVVLPVVSSASPEGHLPETCDQETDQPLTNVLDRQLSREELLQVRTTPQMILLCAWRSSKEVCLILG----ELVQRAPLEEEEDEEQQQQQGDFLLSRAQLEAIGEHFLQLLAETKHRGAFEQAYVGFTMLCRRFWHSESVRLNQLPGQWVDEAMAMVSGQEEWAGKGARLCATRRSAGMPFMLQALVGTE-LKLGTHATLYRCMNRLLEVCERRTGGAAGITAR-SHALNIMRALFRSSELAELVTEFMARGIQCALDGLLLAEEWAERNSATLLLAALIVRVFGVERARLETGELHVR-NRMTGRIFFTRYPQLFDYFHAALQRESEQMDAGGGGSENASGKRRQAVQLEAMLLMLSRLYP 1207
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Zebrafish
Match: thada (THADA armadillo repeat containing [Source:ZFIN;Acc:ZDB-GENE-050320-49])

HSP 1 Score: 179.874 bits (455), Expect = 9.845e-47
Identity = 190/805 (23.60%), Postives = 359/805 (44.60%), Query Frame = 3 
Query:  801 ERILGSVLNEGFVEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLV------NGIIRQNIDSSQ--------AVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLI-----FNSFDSGI-IFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTK---PLVDHYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEEYK------LLPHVIADQ---LIARLECSL------------------ESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISS-------QLSVTRIISLCYAINDV------------IFPFN----SSAAPEGCL-------------------PDEVRNLLDSHFVES--------HP------------EYLTICCWRSCKEISLILGNIAAELV---------NKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRI--IHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYP----ILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIR-VSXXXXXXXXXXGESVLSIDTIRDLTQQIIDCPRNHNLIHGSI 2822
            E++ G ++    +++A V   + VRM+   +LC+        +    + I  FL  NL+  S  +RQ  V+  ++L+        ++++ +D  +        ++  EFL      L + L+P ASF +    L +L +I     FN+   G  + +++  S A+ V+F        A  F E +  A      L ++     + +  +SL Q+AL+ S ++ P D   +  +   LL  E  +      +  H +  Q   LI  LE S+                  E +K+ + L   A + P Y   +C+  +L +  +N  S       +  V+ +I+LCY ++DV            + P +    SSA  +  L                   P    + ++   VES        +P            + + +CCWR+ KE+S++LG++   +           +     +QV+ +  +F  Q+    H+GAFE    GF +L + L RS + ++ ++P  ++++ ++ + +++    LC+TRRSAG+P     L++SEP        L   M  L ++ +  +++ S D   +  +H  NI R LF+++ L   ++      ++ ++  +SS +W +RNS+TLL+  LI RIFG  K    H+K NR+  + FF R+  +Y F+++ ++E   S  + +   +++P    +LV+LGRL P     +SS   L      I     S+V+  R +SA   +  + + +  ++I T+ +   Q +      N IHG++
Sbjct:  617 EKLWGCLVPIPLMQQALVHKHDQVRMDALGLLCETHRSTETVSKDEMDLIRHFLPFNLNSQSPGIRQQTVSLLKKLLCRVKDSAQLLQKRLDQHETDTDQEILSMYKEFLHWFCETLFQVLHPGASFSRCLMALHLLGIIAEHFTFNTGTGGFALGEVVSASHAQGVLFC------LASNFLEVKQLACNLLKKLPSSAVQLQVPERLQSLLQVALDLSISNKPFDSITSAHLFNLLLHQEGLQDALFSCIRKHHLPFQPPALIQSLEASILEQNALTVVQWLMTCLKDEILKAELSLLQAAASFPLYGRAHCITAILQQ--QNTGSLVLLTQWRAVVSELIALCYRMSDVVSPVVQSSSPEGLIPMDAESDSSAGLQNILQEIQPRDSNDFFTSAKKLEPSTTGHNIEQQDVESTIHKPPICNPGDGNGEAYRVTSQMVLVCCWRTMKEVSMLLGHLCHSMPLCCPLTHPDGRGVITEDQVEGVGMYFRKQLLQSRHRGAFELAYVGFVRLTEMLCRSGSAKLQQLPAHWMKEVLEEVKSSDPSSKLCATRRSAGIPFYIQALLSSEP--KSSCGLLKMTMRSLMALAMPCNNETS-DSSSVPQVHALNILRALFRDTRLGENIVPFVSEGMQAAILGYSSPVWAVRNSSTLLFSTLITRIFGVKKDKDEHSKKNRMTGREFFTRFPALYPFLLSQLQEATISVNSDSGQVKLHPSLFLLLVVLGRLYPSPMDGSSSPLGLAPFIPLIISCGRSAVYRTREMSARALVPFVLVTQVPITIQTLLEELPQELGSEIQQNHIHGTL 1410

HSP 2 Score: 29.261 bits (64), Expect = 9.845e-47
Identity = 39/169 (23.08%), Postives = 71/169 (42.01%), Query Frame = 1 
Query:  247 IRNNTTSVLSSGLSIHLNKCQKCSR-------TVLCRELFQRLLKLFQQSWNVSGKFSFINIFIRVFSGEVIRKIEPKIELILLQTAQEYSLSTYACDSYISLLTASNNSSIGIEL-----IVEIFHRE--NPETSFSNIDSIRKT--ICEYFVPKLTQENCGKLTEIV 705
            +R+ T S+  + L+IH    Q CS             +L Q LL L    W++ GK+  +   +     E + K++  +   LL    + +L+ YA D  +  L  S+ + + +        ++ +H     P         + +T  I +YF+PKL + N   L  +V
Sbjct:  416 VRHQTRSLFQNLLTIH----QHCSNHKSDPTSDPYLTQLTQDLLAL---EWHMKGKYGTLACLVEHIGAEYLLKLDSGLPSRLLGLMGDQTLAPYASD-LLEKLFVSHKAQLCMRFKNGHGWIDRWHEVWVTPLLQVLCTAQLDQTTYILDYFLPKLLRCNPNSLGHMV 576
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Zebrafish
Match: thada (THADA armadillo repeat containing [Source:ZFIN;Acc:ZDB-GENE-050320-49])

HSP 1 Score: 157.918 bits (398), Expect = 1.917e-38
Identity = 101/368 (27.45%), Postives = 193/368 (52.45%), Query Frame = 3 
Query: 1776 EYLTICCWRSCKEISLILGNIAAELV---------NKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRI--IHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYP----ILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIR-VSXXXXXXXXXXGESVLSIDTIRDLTQQIIDCPRNHNLIHGSI 2822
            + + +CCWR+ KE+S++LG++   +           +     +QV+ +  +F  Q+    H+GAFE    GF +L + L RS + ++ ++P  ++++ ++ + +++    LC+TRRSAG+P     L++SEP        L   M  L ++ +  +++ S D   +  +H  NI R LF+++ L   ++      ++ ++  +SS +W +RNS+TLL+  LI RIFG  K    H+K NR+  + FF R+  +Y F+++ ++E   S  + +   +++P    +LV+LGRL P     +SS   L      I     S+V+  R +SA   +  + + +  ++I T+ +   Q +      N IHG++
Sbjct:  161 QMVLVCCWRTMKEVSMLLGHLCHSMPLCCPLTHPDGRGVITEDQVEGVGMYFRKQLLQSRHRGAFELAYVGFVRLTEMLCRSGSAKLQQLPAHWMKEVLEEVKSSDPSSKLCATRRSAGIPFYIQALLSSEP--KSSCGLLKMTMRSLMALAMPCNNETS-DSSSVPQVHALNILRALFRDTRLGENIVPFVSEGMQAAILGYSSPVWAVRNSSTLLFSTLITRIFGVKKDKDEHSKKNRMTGREFFTRFPALYPFLLSQLQEATISVNSDSGQVKLHPSLFLLLVVLGRLYPSPMDGSSSPLGLAPFIPLIISCGRSAVYRTREMSARALVPFVLVTQVPITIQTLLEELPQELGSEIQQNHIHGTL 525
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Zebrafish
Match: thada (THADA armadillo repeat containing [Source:ZFIN;Acc:ZDB-GENE-050320-49])

HSP 1 Score: 157.532 bits (397), Expect = 2.590e-38
Identity = 101/368 (27.45%), Postives = 193/368 (52.45%), Query Frame = 3 
Query: 1776 EYLTICCWRSCKEISLILGNIAAELV---------NKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRI--IHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYP----ILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIR-VSXXXXXXXXXXGESVLSIDTIRDLTQQIIDCPRNHNLIHGSI 2822
            + + +CCWR+ KE+S++LG++   +           +     +QV+ +  +F  Q+    H+GAFE    GF +L + L RS + ++ ++P  ++++ ++ + +++    LC+TRRSAG+P     L++SEP        L   M  L ++ +  +++ S D   +  +H  NI R LF+++ L   ++      ++ ++  +SS +W +RNS+TLL+  LI RIFG  K    H+K NR+  + FF R+  +Y F+++ ++E   S  + +   +++P    +LV+LGRL P     +SS   L      I     S+V+  R +SA   +  + + +  ++I T+ +   Q +      N IHG++
Sbjct:  153 QMVLVCCWRTMKEVSMLLGHLCHSMPLCCPLTHPDGRGVITEDQVEGVGMYFRKQLLQSRHRGAFELAYVGFVRLTEMLCRSGSAKLQQLPAHWMKEVLEEVKSSDPSSKLCATRRSAGIPFYIQALLSSEP--KSSCGLLKMTMRSLMALAMPCNNETS-DSSSVPQVHALNILRALFRDTRLGENIVPFVSEGMQAAILGYSSPVWAVRNSSTLLFSTLITRIFGVKKDKDEHSKKNRMTGREFFTRFPALYPFLLSQLQEATISVNSDSGQVKLHPSLFLLLVVLGRLYPSPMDGSSSPLGLAPFIPLIISCGRSAVYRTREMSARALVPFVLVTQVPITIQTLLEELPQELGSEIQQNHIHGTL 517
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Zebrafish
Match: si:ch211-225b11.4 (si:ch211-225b11.4 [Source:ZFIN;Acc:ZDB-GENE-060526-114])

HSP 1 Score: 115.161 bits (287), Expect = 4.150e-25
Identity = 110/441 (24.94%), Postives = 203/441 (46.03%), Query Frame = 3 
Query: 1764 ESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDNFN----QVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQL---NSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKEC--DKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIRVSXXXXXXXXXXGESVLS--IDTIRDLTQQ--IIDCPRNHNLIHGSIKAIRCIFEDLLDNLFISDNQWALLRGISAEIWNRLSPVILSLRTDSRCP---QEFIDLIEFIHGK-SSKFLEQIN 3035
            E H   LT CCW S KEI + LG++   +++   +       +++  +  F D I    H GA E  C GF K C++L  SS  +I +IP   +++ + ++ +      TRR+AGLP L L ++ +E   +K R  L   ++ L      L+ +D   + D  ++  +  + + L K SSL   ++  T +    S+   SS  W +RN+A  LY +L  R+ G  K  +  +  + +++  FF+ Y  +  F+   ++    D     L     +YP+L +L +L P  +     +  L+     +    +S V+ +RV ++KA+ A+      ++  +  ++DL +   ++ C   HN +HG +   R I    L +         ++    + +W   S          RCP   Q ++D++  I G  S+ FL Q++
Sbjct:  974 EEHSLVLT-CCWVSLKEIGIFLGSLVERILSLHCEELKLSVEELRTASKVFKDIILKCRHWGAVEGCCVGFTKFCRALLSSSDPDIRQIPSLMLQQGLSVLQSPSSTSVTRRAAGLPMLILGVLAAED-SSKSRPLLAHTINTLLDTAKALLPSDWDQTLDLPQVCAVHTL-QALVKGSSLGVAVLQFTPAMAVLSLTLLSSACWAMRNAALQLYSSLCTRMLGQQKAGEGSSN-SGMSAASFFHLYPALQPFLQGALETAANDLHDATLLLHPALYPVLTLLSKLQPGAE---KQTRALSEFLPPLLLLSASPVYGVRVMSSKALVAMIPTSEYMATVLQLVKDLPESPDVVSC---HNRLHGKLLQTRAILTRALRSSVSLSLS-EVVDVFESRLWLGSS--------KQRCPLVRQSYVDIVRLIRGHCSAGFLSQLS 1395
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Xenopus
Match: pxn (paxillin [Source:Xenbase;Acc:XB-GENE-941407])

HSP 1 Score: 167.162 bits (422), Expect = 7.793e-41
Identity = 157/680 (23.09%), Postives = 288/680 (42.35%), Query Frame = 3 
Query:  834 FVEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGI---------------------IRQNIDSSQAVST--EFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFL------KTLVYFFADTFEENRMNASKCFIILVNTKPLV---DHYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLLPHVIADQLIARLEC------------SLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP---------------------------DEVRNLLDSHFVESHPE-------------YLTICCWRSCKEISLILGNIAAELVNKSSDN-------FNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRI--IHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYP 2570
             +++  V   + VR++   +LC+        +      +L  L  NL+  S  +RQ      ++L   I                     +R   DSS A+    EF+A +   L  +L+  +S   R S L +L         G I ++  + + E  +F+      + L+   ++TFEE ++ A   F++L    P V        L Q A++ S ++   DC  A  ++  L+  E   +    +       + C             +E +++ + L   A + P Y  ++C+  LL +      S ++     +  ++ + Y ++ ++ P   S++PEG +P                            + R L      +  PE              + +CCWRS KE+SL+LG +   L   +  +         QV+++ ++F   +    H+GAFE    GF KL + L       +  +P  ++   ++ I +++    LC+TRRSAG+P     L+ SEP  N +   L   M QL S L   +S  S D+  I  +H  NI R LF+++ L   +I +     + ++  F+S IW +RNS+TLL+  LI RIFG  +     +K NR+  + FF+R+  +Y F++  ++    +  +    ++++P
Sbjct:  591 LIQQGLVHKHDQVRVDALGLLCESHWSTEVVSLDEMKLVLFCLQYNLNCQSPSIRQQLCYMLKKLFCRIHESSQVLYKQEQTKKLNIAKDVRNVGDSSLALQQYQEFMASVTNSLFESLFAGSSHPTRFSALTIL---------GAIAEIFPVEEGEEGVFVYIQKHVQALLECLSNTFEEVKVLA---FVLLRKLTPCVLDSARLHLLLQAAMDLSTSTKHFDCVTASYLLNFLMCQEALPVALDALDQNQPGPVVCWSRNTEYLMNKLGVEIVQAEMSLLQAAASFPLYGRVHCIIGLLQQLPLKELSMVAEWRDLIGELLLMSYRLSAIVSPVVHSSSPEGLMPMDTDTEAAAQLHMIMSEIQPRDTNDYFSQPRTLQKDLHSQPLPEDTAPGSSCSVTAQMVLVCCWRSMKEVSLLLGMLCQNLPLMTEPDSPRGLITVEQVKEMGEYFKHHLLQSRHRGAFELAYVGFAKLTEMLIGCKEESLRRLPGQWLCSVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEP-KNSKAGFLKMTMKQLIS-LAMPESDASGDKSTIPQVHALNILRALFRDTRLGENVIPYVAEGTQAAILGFTSPIWAVRNSSTLLFSTLITRIFGVKRGKDERSKKNRMTGREFFSRFPALYPFLLEQLEVVADTVDSPTGESKLHP 1256
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Xenopus
Match: pxn (paxillin [Source:Xenbase;Acc:XB-GENE-941407])

HSP 1 Score: 164.081 bits (414), Expect = 7.340e-40
Identity = 158/683 (23.13%), Postives = 290/683 (42.46%), Query Frame = 3 
Query:  834 FVEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGI---------------------IRQNIDSSQAVST--EFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSF--DSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLKQIALEKSNTSNPHDCAVAFTIMKTLL----------GIEEYKLLPHVIADQLIARLECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP---------------------------DEVRNLLDSHFVESHPE-------------------------YLTICCWRSCKEISLILGNIAAELVNKSSDN-------FNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRI--IHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYP 2570
             +++  V   + VR++   +LC+        +      +L  L  NL+  S  +RQ      ++L   I                     +R   DSS A+    EF+A +   L  +L+  +S   R S L +L  I   F  + G    +  +  A     ++ L+   ++TFEE ++ A   F++L N          L Q A++ S ++   DC  A  ++  L+           +++ +  P V    L+ +L   +E +++ + L   A + P Y  ++C+  LL +      S ++     +  ++ + Y ++ ++ P   S++PEG +P                            + R L      +  PE                          + +CCWRS KE+SL+LG +   L   +  +         QV+++ ++F   +    H+GAFE    GF KL + L       +  +P  ++   ++ I +++    LC+TRRSAG+P     L+ SEP  N +   L   M QL S L   +S  S D+  I  +H  NI R LF+++ L   +I +     + ++  F+S IW +RNS+TLL+  LI RIFG  +     +K NR+  + FF+R+  +Y F++  ++    +  +    ++++P
Sbjct:  602 LIQQGLVHKHDQVRVDALGLLCESHWSTEVVSLDEMKLVLFCLQYNLNCQSPSIRQQLCYMLKKLFCRIHESSQVLYKQEQTKKLNIAKDVRNVGDSSLALQQYQEFMASVTNSLFESLFAGSSHPTRFSALTILGAIAEIFPVEEGSCQSVFHLGPAVQAQHVQALLECLSNTFEEVKVLA---FVLLRNVL-KGKLLHLLLQAAMDLSTSTKHFDCVTASYLLNFLMCQEALPVALDALDQNQPGPVVSVRYLMNKL--GVEIVQAEMSLLQAAASFPLYGRVHCIIGLLQQLPLKELSMVAEWRDLIGELLLMSYRLSAIVSPVVHSSSPEGLMPMDTDTEAAAQLHMIMSEIQPRDTNDYFSQPRTLQKDLHSQPLPEDTAPANSLCTEMKGSEGSSCSVTAQMVLVCCWRSMKEVSLLLGMLCQNLPLMTEPDSPRGLITVEQVKEMGEYFKHHLLQSRHRGAFELAYVGFAKLTEMLIGCKEESLRRLPGQWLCSVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEP-KNSKAGFLKMTMKQLIS-LAMPESDASGDKSTIPQVHALNILRALFRDTRLGENVIPYVAEGTQAAILGFTSPIWAVRNSSTLLFSTLITRIFGVKRGKDERSKKNRMTGREFFSRFPALYPFLLEQLEVVADTVDSPTGESKLHP 1276
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Xenopus
Match: pxn (paxillin [Source:Xenbase;Acc:XB-GENE-941407])

HSP 1 Score: 162.54 bits (410), Expect = 2.029e-39
Identity = 158/687 (23.00%), Postives = 291/687 (42.36%), Query Frame = 3 
Query:  834 FVEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGI---------------------IRQNIDSSQAVST--EFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFL--------KTLVYFFADTFEENRMNASKCFIILVNTKPLV---DHYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLLPHVIADQLIARL-----ECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP---------------------------DEVRNLLDSHFVESHPE-------------------------YLTICCWRSCKEISLILGNIAAELVNKSSDN-------FNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRI--IHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYP 2570
             +++  V   + VR++   +LC+        +      +L  L  NL+  S  +RQ      ++L   I                     +R   DSS A+    EF+A +   L  +L+  +S   R S L +L         G I ++  + + E  +F+        + L+   ++TFEE ++ A   F++L    P V        L Q A++ S ++   DC  A  ++  L+  E    LP  +  + +  +     +  +E +++ + L   A + P Y  ++C+  LL +      S ++     +  ++ + Y ++ ++ P   S++PEG +P                            + R L      +  PE                          + +CCWRS KE+SL+LG +   L   +  +         QV+++ ++F   +    H+GAFE    GF KL + L       +  +P  ++   ++ I +++    LC+TRRSAG+P     L+ SEP  N +   L   M QL S L   +S  S D+  I  +H  NI R LF+++ L   +I +     + ++  F+S IW +RNS+TLL+  LI RIFG  +     +K NR+  + FF+R+  +Y F++  ++    +  +    ++++P
Sbjct:  592 LIQQGLVHKHDQVRVDALGLLCESHWSTEVVSLDEMKLVLFCLQYNLNCQSPSIRQQLCYMLKKLFCRIHESSQVLYKQEQTKKLNIAKDVRNVGDSSLALQQYQEFMASVTNSLFESLFAGSSHPTRFSALTIL---------GAIAEIFPVEEGEEGVFVYIQKAQHVQALLECLSNTFEEVKVLA---FVLLRKLTPCVLDSARLHLLLQAAMDLSTSTKHFDCVTASYLLNFLMCQEA---LPVALDGRWLFPVRYLMNKLGVEIVQAEMSLLQAAASFPLYGRVHCIIGLLQQLPLKELSMVAEWRDLIGELLLMSYRLSAIVSPVVHSSSPEGLMPMDTDTEAAAQLHMIMSEIQPRDTNDYFSQPRTLQKDLHSQPLPEDTAPANSLCTEMKGSEGSSCSVTAQMVLVCCWRSMKEVSLLLGMLCQNLPLMTEPDSPRGLITVEQVKEMGEYFKHHLLQSRHRGAFELAYVGFAKLTEMLIGCKEESLRRLPGQWLCSVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEP-KNSKAGFLKMTMKQLIS-LAMPESDASGDKSTIPQVHALNILRALFRDTRLGENVIPYVAEGTQAAILGFTSPIWAVRNSSTLLFSTLITRIFGVKRGKDERSKKNRMTGREFFSRFPALYPFLLEQLEVVADTVDSPTGESKLHP 1261
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Xenopus
Match: pxn (paxillin [Source:Xenbase;Acc:XB-GENE-941407])

HSP 1 Score: 161.77 bits (408), Expect = 3.831e-39
Identity = 159/687 (23.14%), Postives = 291/687 (42.36%), Query Frame = 3 
Query:  834 FVEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGI---------------------IRQNIDSSQAVST--EFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLV------DHYESLKQIALEKSNTSNPHDCAVAFTIMKTLL----------GIEEYKLLPHVIADQLIARLECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP---------------------------DEVRNLLDSHFVESHPE-------------------------YLTICCWRSCKEISLILGNIAAELVNKSSDN-------FNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRI--IHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYP 2570
             +++  V   + VR++   +LC+        +      +L  L  NL+  S  +RQ      ++L   I                     +R   DSS A+    EF+A +   L  +L+  +S   R S L +L  I   F        ++   A++V   + L+   ++TFEE ++ A   F++L    P V           L Q A++ S ++   DC  A  ++  L+           +++ +  P V    L+ +L   +E +++ + L   A + P Y  ++C+  LL +      S ++     +  ++ + Y ++ ++ P   S++PEG +P                            + R L      +  PE                          + +CCWRS KE+SL+LG +   L   +  +         QV+++ ++F   +    H+GAFE    GF KL + L       +  +P  ++   ++ I +++    LC+TRRSAG+P     L+ SEP  N +   L   M QL S L   +S  S D+  I  +H  NI R LF+++ L   +I +     + ++  F+S IW +RNS+TLL+  LI RIFG  +     +K NR+  + FF+R+  +Y F++  ++    +  +    ++++P
Sbjct:  546 LIQQGLVHKHDQVRVDALGLLCESHWSTEVVSLDEMKLVLFCLQYNLNCQSPSIRQQLCYMLKKLFCRIHESSQVLYKQEQTKKLNIAKDVRNVGDSSLALQQYQEFMASVTNSLFESLFAGSSHPTRFSALTILGAIAEIFP-------VEEVQAQHV---QALLECLSNTFEEVKVLA---FVLLRKLTPCVLVSKDSARLHLLLQAAMDLSTSTKHFDCVTASYLLNFLMCQEALPVALDALDQNQPGPVVSVRYLMNKL--GVEIVQAEMSLLQAAASFPLYGRVHCIIGLLQQLPLKELSMVAEWRDLIGELLLMSYRLSAIVSPVVHSSSPEGLMPMDTDTEAAAQLHMIMSEIQPRDTNDYFSQPRTLQKDLHSQPLPEDTAPANSLCTEMKGSEGSSCSVTAQMVLVCCWRSMKEVSLLLGMLCQNLPLMTEPDSPRGLITVEQVKEMGEYFKHHLLQSRHRGAFELAYVGFAKLTEMLIGCKEESLRRLPGQWLCSVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEP-KNSKAGFLKMTMKQLIS-LAMPESDASGDKSTIPQVHALNILRALFRDTRLGENVIPYVAEGTQAAILGFTSPIWAVRNSSTLLFSTLITRIFGVKRGKDERSKKNRMTGREFFSRFPALYPFLLEQLEVVADTVDSPTGESKLHP 1215
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Xenopus
Match: pxn (paxillin [Source:Xenbase;Acc:XB-GENE-941407])

HSP 1 Score: 152.525 bits (384), Expect = 2.658e-36
Identity = 137/588 (23.30%), Postives = 253/588 (43.03%), Query Frame = 3 
Query: 1089 AKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSF--DSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLV---DHYESLKQIALEKSNTSNPHDCAVAFTIMKTLL----------GIEEYKLLPHVIADQLIARL----------ECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP---------------------------DEVRNLLDSHFVESHPE-------------------------YLTICCWRSCKEISLILGNIAAELVNKSSDN-------FNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRI--IHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYP 2570
            A +   L  +L+  +S   R S L +L  I   F  + G    +  +  A     ++ L+   ++TFEE ++ A   F++L    P V        L Q A++ S ++   DC  A  ++  L+           +++ +  P V   +   R+          +  +E +++ + L   A + P Y  ++C+  LL +      S ++     +  ++ + Y ++ ++ P   S++PEG +P                            + R L      +  PE                          + +CCWRS KE+SL+LG +   L   +  +         QV+++ ++F   +    H+GAFE    GF KL + L       +  +P  ++   ++ I +++    LC+TRRSAG+P     L+ SEP  N +   L   M QL S L   +S  S D+  I  +H  NI R LF+++ L   +I +     + ++  F+S IW +RNS+TLL+  LI RIFG  +     +K NR+  + FF+R+  +Y F++  ++    +  +    ++++P
Sbjct:  643 ASVTNSLFESLFAGSSHPTRFSALTILGAIAEIFPVEEGSCQSVFHLGPAVQAQHVQALLECLSNTFEEVKVLA---FVLLRKLTPCVLDSARLHLLLQAAMDLSTSTKHFDCVTASYLLNFLMCQEALPVALDALDQNQPGPVVCWSRNTERVIVSNILYLMNKLGVEIVQAEMSLLQAAASFPLYGRVHCIIGLLQQLPLKELSMVAEWRDLIGELLLMSYRLSAIVSPVVHSSSPEGLMPMDTDTEAAAQLHMIMSEIQPRDTNDYFSQPRTLQKDLHSQPLPEDTAPANSLCTEMKGSEGSSCSVTAQMVLVCCWRSMKEVSLLLGMLCQNLPLMTEPDSPRGLITVEQVKEMGEYFKHHLLQSRHRGAFELAYVGFAKLTEMLIGCKEESLRRLPGQWLCSVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEP-KNSKAGFLKMTMKQLIS-LAMPESDASGDKSTIPQVHALNILRALFRDTRLGENVIPYVAEGTQAAILGFTSPIWAVRNSSTLLFSTLITRIFGVKRGKDERSKKNRMTGREFFSRFPALYPFLLEQLEVVADTVDSPTGESKLHP 1225
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Mouse
Match: Thada (thyroid adenoma associated [Source:MGI Symbol;Acc:MGI:3039623])

HSP 1 Score: 146.362 bits (368), Expect = 1.494e-34
Identity = 162/675 (24.00%), Postives = 286/675 (42.37%), Query Frame = 3 
Query:  867 NVRMEMFAILCKEISRQNQRNYQLWNQILRFLIS-NLSIASNKLRQHFVNCFRQLV-----------------------NGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSG-----IIFDLL-DMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIIL--VNTKPLVD--HYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLLPHVIADQLIAR----------------LECSLESIKSNI-----ELFHIAMNSPFYSSLYCL-----RYLLDEHFENISSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLP---------------------------------------------DEVRNLLDSHFVESHPE-------YLTICC-WRSCKEIS----LILGNIAAELVNKSSDNF---NQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSS-LNFAMDQLNSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIK 2519
             VR++   +LC E +R  +       Q ++F I+ NL+  S  +RQ   +  ++L                        NG IR+    +      F++ +   L   L+P +S+  R S L +L  +   F         ++ L  D+    Y I ++     F  TFEE +  A    + L  V      D    + L Q ALE S ++ P+DC  A  ++  L+  +    +    + Q + R                ++C +E+++  I      L   A + P Y  ++C+     R  L++       +  + R++ L Y ++ V+ P   S++PEG +P                                               V N+  S  V+   E        + + C WRS KE++     +   +  +   +SS+ F    QV++I D+F   +    H+GAFE    GF KL + L R S + + ++P  ++R  ++ I  ++    LC+TRRSAG+P     L+ SEP   K R   L   M +L S+ + AD  +S  +   +H  NI R LF+++ L   +I +     K ++  F+S +W +RNS+TLL+ +LI R+FG  +     +K NR+  + FF+R+  +Y F++  ++
Sbjct:  627 QVRIDTLGLLC-ESNRSTEVVSTEEMQWVQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSTPDSENGSIREQPSVTLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSVAEVFPDPEGNIQTVYQLSHDIDAGRYQILMEC----FTSTFEEVKTLAFDLLMKLSSVTAGQFQDSEKLQDLFQAALELSTSTKPYDCVTASYLLNLLIRQDALPAVLSASSPQQLTRGAGETSAVLERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQRLPLNDLRLASEWRPLLGRLLLLSYRLSTVVAPVIQSSSPEGLIPVDTDSASASRLQLILNEIQPRDTNDYFNHTKILKECDSFDLEDLSTSVSNIDSSAEVKGKEEKACDVTAQMVLACCWRSMKEVALLLGTLCQLLPVQPGPESSNVFLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLRSVLEEIKGSDPSSKLCATRRSAGIPFYIQALLASEP--KKSRMDLLKITMRELISLALSAD--DSKGRVPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILGFTSPVWAVRNSSTLLFSSLITRVFGVKRGKDEVSKTNRMTGREFFSRFPELYPFLLKQLE 1292
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. UniProt/SwissProt
Match: sp|A8C750|THADA_CANLF (Thyroid adenoma-associated protein homolog OS=Canis lupus familiaris OX=9615 GN=THADA PE=2 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 9.753e-39
Identity = 168/675 (24.89%), Postives = 291/675 (43.11%), Query Frame = 3 
Query:  867 NVRMEMFAILCKEISRQNQRNYQLWNQILRFLIS-NLSIASNKLRQHFVNCFRQLV-----------------------NGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFD--SGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLK---QIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLLPHVIADQLIAR---------------------LECSLESIKSNIE-----LFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP----DEVRNLLDSHFVESHP----EYLT---------------------------------------------ICCWRSCKEISLILGNIAA----ELVNKSSDNF---NQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKAD-SQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIK 2519
             VR++   +LC E +R  +       Q ++F I+ NL+  S  +RQ   +  ++L                        N + +Q+   S      F++ +  +L   L+P +S+  R S L +L  I   F    G +  +  +S    V   +TL+  F  TFEE ++ A    + L  T       E L+   Q ALE S+++ P+DC  A  ++  L+  +   +LP  + D L  +                     ++C LE+++  +      L   A + P Y  ++C+   L     N    +S     + +++ + Y ++ V+ P   S++PEG +P     E  + L +   E  P    +Y T                                             +CCWRS KE++L+LG +      + V +SS+      QV++I D+F   +    H+GAFE    GF KL + L R   + + ++P  ++   ++ I  ++    LC+TRRSAG+P     L+ SEP   K    L   M +L S+    D SQ++  Q   +H  NI R LF+++ L   +I +     K ++  F+S +W +RNS+TLL+  LI RIFG  +     +K NR+    FF+R+  +Y F++  ++
Sbjct:  632 QVRIDTLGLLC-ESNRSTEIVSTEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKQEQSRSKHEPENELTKQHPSVSLQQYKNFMSSICSHLFEALFPGSSYPTRFSALTILGSIAEVFPVTEGQVQAVYQLSHDIDVGRFQTLMECFTSTFEEVKILAFDLLMKLPKTVVQFQDSEKLQGLFQAALELSSSTKPYDCVTASYLLNFLIWQD---VLPSSLFDSLKTQQTACEDGDKSAIVVERNTLMVIKCLLENLEEEVSQAENSLLQAAASFPLYGRVHCVTGALQRLSLNNLQLVSEWRPVIEKLLLMSYRLSAVVSPVIQSSSPEGLIPMDTDSESASRLQTILNEIQPRDTNDYFTQAKILKEHDSFDLEDLNVSVQNIGASAEVKGKERKTCDVTAQMVLVCCWRSMKEVALLLGTLCQLLPMQSVPESSNGLLTEEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCPNVSLQKLPEQWLWNVLEEIKCSDPSSKLCATRRSAGIPFYIQALLASEPKKGKM-DLLKITMKELISLAGPTDDSQSTVPQ---VHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSTLITRIFGVKRGKDELSKKNRMTGSEFFSRFPELYPFLLQQLE 1298
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. UniProt/SwissProt
Match: sp|A8C754|THADA_CHICK (Thyroid adenoma-associated protein homolog OS=Gallus gallus OX=9031 GN=THADA PE=2 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 1.870e-34
Identity = 146/601 (24.29%), Postives = 267/601 (44.43%), Query Frame = 3 
Query: 1080 EFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIF----------LKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLK---QIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLL---------PHVIADQLIARLECSL-------------ESIKSNIELFHIAMNSPFYSSLYCLRYLLDE------HFENISSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLPDEV--------------------------RNLLDSH-------FVESHP--------------------EYLTICCWRSCKEISLILGNIAAELVNKSSD-------NFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHT---NEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYP 2570
            +FL+ L   L   L+P +S   R S L++L         G + ++  +   +  +F          ++TL+  FA TFEE ++ A +  + L +    +   ESL    Q A++ S ++ P+DC  A  ++  L   E+ + +         P +  D  +  +E ++             E  ++   L   A + P Y  ++C+   L +       F     Q+ V R+I + Y ++ V+ P   S++PEG +P ++                            +L  H         E  P                    + + +CCWRS KE+SL+LG +   L  ++S           QV+ I D+F   +    H+GAFE    GF +L ++L R ++  + ++P  ++R  ++ I +   +  LC+TRRSAG+P     L+ SEP   K    L   + +L S+   +    SA  +  +H  NI R LF+++ L   ++ +    ++ ++  F+S IW +RNS+TLL+ ALI RIFG  +    ++K NR+    FF+R+ ++Y F++  ++    +  + +   +I+P
Sbjct:  723 DFLSSLCDRLFEALFPGSSHPTRFSALSIL---------GSVAEIFSVQKGQEQVFRLDQEINSARVRTLIQCFASTFEEVKVLAFELLMKLRDVVFXLQDSESLDLLFQAAMDLSTSTKPYDCVTASYLLNFLAYHEDLQHICLGKWIKHNPQMNEDTSVGTVEKNILAVIKLLLVNVEEEIFQAKKSLLQAAASFPMYGRVHCINGALQQLPLNNLMFVTEWKQI-VARLILMSYELSAVVSPVVQSSSPEGLIPMDIDSETADRLHMILKEIQPQDTNDYFMQAKMLKEHCKIQSEKLAEHKPMENICTEMRGKESQICDVTAQMVLVCCWRSMKEVSLLLGTLCKLLPTQASSEPSHGLITVEQVKNIGDYFKHHLMQSRHRGAFELAYAGFVQLTETLSRCNSESLRKMPEQWLRCVLEEIKSCDPSSTLCATRRSAGIPFYIQALLASEPKKGKM-DLLKMTIKELMSLASPSSEPPSAIPQ--VHALNILRALFRDTRLGENIMPYVADGIQAAILGFTSPIWAVRNSSTLLFSALITRIFGVKRGKDENSKKNRMTGAEFFSRFPSLYPFLLKQLEVVANTLNSEDEELKIHP 1310
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. UniProt/SwissProt
Match: sp|A8C756|THADA_MOUSE (Thyroid adenoma-associated protein homolog OS=Mus musculus OX=10090 GN=Thada PE=1 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 1.045e-33
Identity = 162/675 (24.00%), Postives = 286/675 (42.37%), Query Frame = 3 
Query:  867 NVRMEMFAILCKEISRQNQRNYQLWNQILRFLIS-NLSIASNKLRQHFVNCFRQLV-----------------------NGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSG-----IIFDLL-DMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIIL--VNTKPLVD--HYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLLPHVIADQLIAR----------------LECSLESIKSNI-----ELFHIAMNSPFYSSLYCL-----RYLLDEHFENISSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLP---------------------------------------------DEVRNLLDSHFVESHPE-------YLTICC-WRSCKEIS----LILGNIAAELVNKSSDNF---NQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSS-LNFAMDQLNSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIK 2519
             VR++   +LC E +R  +       Q ++F I+ NL+  S  +RQ   +  ++L                        NG IR+    +      F++ +   L   L+P +S+  R S L +L  +   F         ++ L  D+    Y I ++     F  TFEE +  A    + L  V      D    + L Q ALE S ++ P+DC  A  ++  L+  +    +    + Q + R                ++C +E+++  I      L   A + P Y  ++C+     R  L++       +  + R++ L Y ++ V+ P   S++PEG +P                                               V N+  S  V+   E        + + C WRS KE++     +   +  +   +SS+ F    QV++I D+F   +    H+GAFE    GF KL + L R S + + ++P  ++R  ++ I  ++    LC+TRRSAG+P     L+ SEP   K R   L   M +L S+ + AD  +S  +   +H  NI R LF+++ L   +I +     K ++  F+S +W +RNS+TLL+ +LI R+FG  +     +K NR+  + FF+R+  +Y F++  ++
Sbjct:  627 QVRIDTLGLLC-ESNRSTEVVSTEEMQWVQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSTPDSENGSIREQPSVTLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSVAEVFPDPEGNIQTVYQLSHDIDAGRYQILMEC----FTSTFEEVKTLAFDLLMKLSSVTAGQFQDSEKLQDLFQAALELSTSTKPYDCVTASYLLNLLIRQDALPAVLSASSPQQLTRGAGETSAVLERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQRLPLNDLRLASEWRPLLGRLLLLSYRLSTVVAPVIQSSSPEGLIPVDTDSASASRLQLILNEIQPRDTNDYFNHTKILKECDSFDLEDLSTSVSNIDSSAEVKGKEEKACDVTAQMVLACCWRSMKEVALLLGTLCQLLPVQPGPESSNVFLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLRSVLEEIKGSDPSSKLCATRRSAGIPFYIQALLASEP--KKSRMDLLKITMRELISLALSAD--DSKGRVPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILGFTSPVWAVRNSSTLLFSSLITRVFGVKRGKDEVSKTNRMTGREFFSRFPELYPFLLKQLE 1292
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. UniProt/SwissProt
Match: sp|Q6YHU6|THADA_HUMAN (Thyroid adenoma-associated protein OS=Homo sapiens OX=9606 GN=THADA PE=1 SV=1)

HSP 1 Score: 142.124 bits (357), Expect = 2.302e-32
Identity = 88/260 (33.85%), Postives = 144/260 (55.38%), Query Frame = 3 
Query: 1776 EYLTICCWRSCKEISLILGNI----AAELVNKSSDNF---NQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSL-NFAMDQLNSILVKADS-QNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIK 2519
            + + +CCWRS KE++L+LG +      + V +SSD      QV++I D+F   +    H+GAFE    GF KL + L R   + + ++P  ++   ++ I  ++    LC+TRRSAG+P     L+ SEP   K R  L    M +L S+    D  Q++  Q   +H  NI R LF+++ L   +I +     K ++  F+S +W +RNS+TLL+ ALI RIFG  +    H+K NR+  + FF+R+  +Y F++  ++
Sbjct: 1047 QMVLVCCWRSMKEVALLLGMLCQLLPMQPVPESSDGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQALLASEP--KKGRMDLLKITMKELISLAGPTDDIQSTVPQ---VHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSALITRIFGVKRAKDEHSKTNRMTGREFFSRFPELYPFLLKQLE 1301

HSP 2 Score: 58.151 bits (139), Expect = 6.987e-7
Identity = 80/346 (23.12%), Postives = 142/346 (41.04%), Query Frame = 3 
Query:  867 NVRMEMFAILCKEISRQNQRNYQLWNQILRFLIS-NLSIASNKLRQHFVNCFRQLV-----------------------NGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSF--DSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYE------SLKQIALEKSNTSNPHDCAVA-----FTIMKTLLGIEEYKLLPHVIA----DQLIARLE--------CSLESIKSNI-----ELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP 1727
             VR++   +LC E +R  +       Q ++F I+ NL+  S  +RQ   +  ++L                        N + +Q+   S      F++ +   L   L+P +S+  R S L +L  I   F    G I+ +  +S    V   +TL+  F  TFE+ ++ A   F +L+       H++       L Q ALE S ++ P+DC  A     F I +  L       L   +A    D+  A +E        C +E+++  +      L   A   P Y  ++C+   L +   N    +S     V +++ + Y ++ V+ P   S++PEG +P
Sbjct:  636 QVRIDTLGLLC-ESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQHPSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTSTFEDVKILA---FDLLMKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLIWQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENLEEEVSQAENSLLQAAAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIP 977
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. UniProt/SwissProt
Match: sp|A8C752|THADA_CHLAE (Thyroid adenoma-associated protein homolog OS=Chlorocebus aethiops OX=9534 GN=THADA PE=2 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 2.397e-31
Identity = 86/259 (33.20%), Postives = 142/259 (54.83%), Query Frame = 3 
Query: 1776 EYLTICCWRSCKEISLILGNI----AAELVNKSSDNF---NQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNE---DLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADS-QNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIK 2519
            + + +CCWRS KE++L+LG +      + V +SSD      QV++I D+F   +    H+GAFE    GF KL + L R   + + ++P  ++   ++ I  ++    LC+TRRSAG+P     L+ SEP   K    L   M +L S+    D  Q++  Q   +H  NI R LF+++ L   +I +     K ++  F+S +W +RNS+TLL+ ALI RIFG  +     +K NR+  + FF+R+  +Y F++  ++
Sbjct: 1047 QMVLVCCWRSMKEVALLLGTLCQLLPMQPVPESSDGLLTVEQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEIKCSDPSSKLCATRRSAGIPFYIQALLASEPKKGKM-DLLKITMKELISLAGPTDDLQSTVPQ---VHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSALITRIFGVKRAKDELSKTNRMTGREFFSRFPELYPFLLKQLE 1301

HSP 2 Score: 56.6102 bits (135), Expect = 2.515e-6
Identity = 76/361 (21.05%), Postives = 145/361 (40.17%), Query Frame = 3 
Query:  813 GSVLNEGFVEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLIS-NLSIASNKLRQHFVNCFRQLV-----------------------NGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSF--DSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLK---QIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLLPHVIADQLIAR-----------------LECSLESIKSNI-----ELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLS-----VTRIISLCYAINDVIFPFNSSAAPEGCLP 1727
            G+ + +G + +        VR++   +LC E +R  +       Q ++F I+ NL+  S  +RQ   +  ++L                          + +Q+   S      F++ +   L   L+P +S+  R S L +L  I   F    G I+ +  ++    V   + L+  F  TFE+ +M A    + L  T       E L+   Q AL  S ++ P+DC  A  ++  L+  +       V   Q +AR                 ++C +E+++  +      L   A + P Y  ++C+   L +   N    +S     V +++ + Y ++ V+ P   S++PEG +P
Sbjct:  623 GARIKQGLIHQHC-----QVRIDTLGLLC-ESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQNKSKHEPEKELTKQHPSVSLQQYKNFMSSICNSLFEALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLNHDIDVGRFQALMECFTSTFEDVKMLAFDLLMKLSKTAVHFQDSEKLQGLFQAALALSTSTKPYDCVTASYLLNFLIWQDALPSSLSVYLTQQVARGDGDRPASVVERNTLMVIKCLMENLEEEVYQAENSLLQAAASFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSPEGLIP 977
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. TrEMBL
Match: A0A210QPQ6 (Thyroid adenoma-associated protein-like OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT10789 PE=4 SV=1)

HSP 1 Score: 236.498 bits (602), Expect = 7.124e-59
Identity = 219/799 (27.41%), Postives = 382/799 (47.81%), Query Frame = 3 
Query:  786 DSVTRERILGSVLNEGFVEEASVDWDENVRMEMFAILCKEISRQNQRNYQL-----WNQILRFLISNLSIASNKLRQHFVNCFRQLV------NGIIRQNIDSSQAVS-------------TEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSF---DSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIIL---VNTKPLVDHYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEE-YKLLPHVIADQLIARLECS-------LESIKSN------------------------IELFHIAMNSPFYSSLYCLRYLL-DEHFENISSQLS-------VTRIISLCYAINDVIFPFNSSAAPEGCLPDEVRNLLD----------------SHFVESHPEYLTICCWRSCKEISLILG--NIAAELVNKSSDN------FNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRK-SIDIIHTNED--LCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAM-DQLNSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFG--PSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLN----LNSSTRIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIRVSXXXXXXXXXXGESVLSIDTIRDLTQQIIDCP------RNHNLIHGSIKAIRCIFEDL 2852
            +S ++E + G+V +   +++A    DE VR+++ A+LC     +NQR+ ++     ++ + +FL  NL+  S   RQH +   ++L          +R+NI + +                 +F+A L+ +    L   +SF +R++ L++L+L+  +       + FDL+    + +   L++L+    DTFEEN+M A+K        +  +  V   E L   AL  + ++ P DC  A  ++K +L  +E Y +L +  +D+  ++L  +       L S+ +N                          L   A N P Y +L+C+RYLL D   +N+    S       +  +I+ C  I++++ P   + +PEG +P E    L+                   V   PEYL +CCWR+ KE+SL+LG  N+A  + +    +       +Q+  +  +F  Q+    H+GAFE    GF K+   LWRS+  E+ E+P  ++++  +DI   + D  LCSTRRSAG+P     L+T+EP  +  RS    AM D L   L+ +    SA   ++ H  N  R L++++ L   + +     ++ ++  F +  W +RNSATLL  ALI R+FG   SK     +K N    + FF+RY ++Y+F+++ +    ++  N    L+    +YPIL++LGRL P       +S +L      + R  SS+V+  R+ +AKA+  L L + + S+     L+Q +   P       N NLIHG +  +  + + L
Sbjct:  609 ESGSQECLYGAV-SVAVIKQAMAHTDEQVRLDVIALLC-----ENQRSTEVISKTEFDLLRQFLPWNLNNQSPSFRQHLLAHLKKLFFRLQESQVTLRRNIKNRKTKPDDGESYRASLDSYQDFVAWLVEHQFLCLSG-SSFARRTTCLSILSLVTTALPYTGDDLGFDLVGCVHSPH---LQSLLECLTDTFEENKMEATKILQYCCQHIGGRQGVSDLEPLFDTALTLAASTRPQDCTTAAYLLKVILVQQEIYDILKN--SDRYQSKLFLTKHRETFCLPSVDNNQSGRSLLLLWILLSYLQDQKEVAKGSLIMAAANRPLYPTLHCIRYLLFDVALKNLPQDQSLPYWQSFIQDLITTCLEISEIVSPVVHNTSPEGNVPVEAIGGLNLDTLLHPNSLKDAERSKETVMLMPEYLVVCCWRNIKEVSLLLGQLNLATPISDPHRPDSGGLLSCDQILVMGKYFRKQLLESVHRGAFELAYAGFVKMADMLWRSNIQELHELPRRWLKEVMVDIQADDPDSKLCSTRRSAGVPFYIQTLVTTEP-TSTGRSCFKQAMTDLLQMALLDSTGLESASNPQV-HALNTLRSLYRDTRLAEDVASFVADGLRAAILGFQNPFWAVRNSATLLLSALITRVFGVKRSKDEGSVSKKNCQTGRAFFHRYPSLYKFLLDQLATATENIGNSEGALHLHPSLYPILMVLGRLFPSHLEGADTSLNLAAFIPYVIRCSSSAVYKTRIMSAKALQPLVLPDQLTSV-----LSQLLGMLPDSGIQSTNQNLIHGLLPQVHQLIQTL 1388
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. TrEMBL
Match: A0A433TA35 (DUF2428 domain-containing protein OS=Elysia chlorotica OX=188477 GN=EGW08_013851 PE=4 SV=1)

HSP 1 Score: 233.032 bits (593), Expect = 8.958e-58
Identity = 199/714 (27.87%), Postives = 340/714 (47.62%), Query Frame = 3 
Query:  822 LNEGFVEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLIS-NLSIASNKLRQHFVNCFRQLVNGI------IRQNIDSSQAVSTE---------FLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSF----DSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFI-ILVNTKPLVDHYESLK--QIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLLPH------VIADQLIARLECSLESIKSNIE---------------------LFHIAMNSPFYSSLYCLRYLLDE-HFENI------SSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLPDEVRNLLD-------SHFVESHPEYLTICCWRSCKEISLILGNIAAEL----VNKSSDN----FNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNED---LCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRI-------IHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFG--PSKTIKFHNKFNRLNSKVFFNRYQNMYEFI-----VNTIKECDKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIRV 2696
            L+   ++EA    D+++R++ FA++C E S+ ++       ++L+F I  N++  S   RQ+ +   ++L+  +      +R+ +    +  T          FL  L  +   NLYP A+F +R++ LA+L+L+  SF    D   I  LL        + ++TL+    DTFEEN+  A       L + +P+ D   +++   +AL  + ++ P DC  A  I   LL  +E+   PH       ++    + LE    ++ SN +                     L   A + P Y +L+C+RY+L E  F  +      S++  +  +I  C  ++ V+ P   +++PEG +P+E  +  D          VES PEYL +C WRS KE+SL LG++  +L    + K ++      +Q++ I  +F  Q+    H+GAFE    GF+ +CQ LW+        +P  ++   +  I + +    LC+TRRSAG+P L   + ++EP +   R   + AM +L  + +  + +   D   +       +H  NI R L++ES L   ++ +    +K ++  F S  W +RNSATLL  AL+ RIFG   SK     +K N    + FF RY  +Y F+     V T     +  L+L+ S  +YP+L++LGRL P     + +S  L+     + R  SS V+  RV
Sbjct:  624 LSSEVLKEALCSMDDHIRLDAFALVC-ENSKTSEVVTIFEFEMLKFFIPHNINNQSPAFRQNLLAQLKKLMFRVKESILSLRRKLKGKTSTQTVCKSINDYECFLTWLTMFTVDNLYPGAAFARRTTSLAILSLLTTSFTSEKDGFCIPALLKK------VHIQTLLGALTDTFEENKREALGILTGFLKHQEPIWDPPGTVETLNVALSLACSTRPQDCDTAVYIFLVLLKQQEF--YPHKFDFAASLSSASGSTLELLDSALSSNPKLLLLRSLLQLLDSQISVAEQSLVSAAASRPMYPTLHCIRYILQELDFSAMEEDHMPSAKNFIKHLIISCLHLSRVVSPVVQNSSPEGNIPEEAVSGPDMPNAEWSRALVESMPEYLVVCGWRSIKEVSLTLGSLCLQLPTDFIVKEAEGGLLSLDQIEVIGRYFNQQLLESIHRGAFELAYAGFQLMCQMLWKHPLSCFHHLPSQWLTAVLQDIKSEDAQSRLCATRRSAGVPFLVQAITSTEPNLTG-RQMFHNAMKELLRLALSQEEKACEDGGNLASSSDAQVHALNILRALYRESRLGDDVVLYVADGLKAAILGFRSEQWAVRNSATLLLSALMTRIFGVKRSKDESAMSKKNCQTGRAFFYRYPTLYPFLLSELEVATANVMSRDRLSLHPS--LYPVLLVLGRLFPSTLEGSDTSLSLSAFIPYVIRCASSPVYKTRV 1325
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BLAST of Thyroid adenoma-associated-like protein vs. TrEMBL
Match: A0A4Y2E5D4 (Thyroid adenoma-associated OS=Araneus ventricosus OX=182803 GN=THADA_1 PE=4 SV=1)

HSP 1 Score: 231.106 bits (588), Expect = 3.222e-57
Identity = 223/769 (29.00%), Postives = 363/769 (47.20%), Query Frame = 3 
Query:  837 VEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGII-------RQNIDSSQAVS---------TEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCF----IILVNTKPLVDHYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEEYK--LLPHVIADQ----LIARLECSLESIKSNIELF--------------HIAMNS--------PFYSSLYCLRYLLDE-HFENISSQLSVTR-------IISLCYAINDVIFPFNSSAAPEGCLP-----DEVRNL-----------LDSHFVESH---PE-----------------YLTICCWRSCKEISLILGNIAAEL-VNKSSD------NFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRK---SIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQ-NSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSST-----RIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIRVSXXXXXXXXXXGESVLS-IDTIRDLTQQIIDCPRNHNLIHG 2816
            +++A    D+ VR+  F+++C+            +  I+  L  NL+  +   RQ  V+  ++L+N ++       R+  DS + V           EFL  L +YL   L+P A+F +R + L +L L+   F   + F       +  +   +TL+Y   DT+E N+  + K      I ++ T+   D +++L + +L  ++++ P D   A  +   ++  + +   LL H++        + +LE    SI SN   F               IA +S        P Y  L C+R ++ E  F+ +    SV         +ISL   +  V+ P  S A+PEG LP     D +  L             S  VES    PE                  L +CCWR+ KE+SL+ G I+  + V+  +D      N  QV+ I D+F DQ+ SV HKGAFE    GF KLC+ LWRS  +E+ E+P +++     +I  +  +++   TRRSAGLP +   ++ SEP ++   SSL F  + ++S+L  A +Q ++ +   ++H  NI R LF++S L   LI     A+  S+  F S+ W +RNS+ LL+ AL+ RIFG S       K NRL  + FF+ Y+ +Y F+ + +K+C  + +N N  +      +YPIL++LGRL P     +S    LT     +     S +W +RV AA+A+  L   E+  S + ++ D   Q      +HN IHG
Sbjct:  583 LQKALTHADDQVRLSAFSMICESPKTTEVVLENAFKLIMELLPYNLNCQAPAFRQQLVSHLKKLLNRMVDSKNAFPRKKADSPELVDFFTSVENAYEEFLKWLKKYLYSCLFPGANFPRRVTVLNLLLLLHKYFPETLSF-------SGTLEETQTLLYALQDTYENNKQISLKILQSVDISILATED-EDCFKTLLETSLILASSTKPPDTVTAAYMFAFMVKSKNFDTVLLNHLLVSMENGPCLLQLEKDSLSIVSNSSAFIGLLLLSCELLKHLKIAQDSLCDAAACAPIYGVLACIRSIISEIDFKTLDDNFSVREWANLIRELISLGIQVAKVVEPVVSHASPEGHLPMDPDSDSISKLQATVRRSIGKRFQSAVVESEDFVPESDQVVLDKVKTHAVSAQILLLCCWRTHKEVSLLFGEISDRIPVSGDNDTESGILNVTQVKDIGDYFMDQMASVQHKGAFEQAYIGFTKLCKMLWRSPILELQELPQNWLNDLCLAIKGLKDDKNFSYTRRSAGLPFIMQAILASEPGIS---SSL-FFKNTISSLLSMASTQKDNGNVDEMVHALNILRALFRDSCLSDVLIPFVSEALMASIIGFKSHYWIVRNSSHLLFSALMTRIFGVSGPQDEVGKKNRLTGRTFFSYYKEIYAFLYDELKQC-AAVMNQNRESLTLVPSLYPILLVLGRLYPAPGECDSR---LTSFIPFLNVCSGSPIWKVRVLAAQALVPLISAENFSSTLQSLFDYLPQNGQIITSHNQIHG 1335
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BLAST of Thyroid adenoma-associated-like protein vs. TrEMBL
Match: A0A4Y2E4B3 (Thyroid adenoma-associated OS=Araneus ventricosus OX=182803 GN=THADA_1 PE=4 SV=1)

HSP 1 Score: 231.106 bits (588), Expect = 3.251e-57
Identity = 222/769 (28.87%), Postives = 361/769 (46.94%), Query Frame = 3 
Query:  837 VEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGII-------RQNIDSSQAVS---------TEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCF----IILVNTKPLVDHYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEEYK--LLPHVIADQ----LIARLECSLESIKSNIELF--------------HIAMNS--------PFYSSLYCLRYLLDE-HFENISSQLSVTR-------IISLCYAINDVIFPFNSSAAPEGCLP-----DEVRNL-----------LDSHFVESH---PE-----------------YLTICCWRSCKEISLILGNIAAEL-VNKSSD------NFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRK---SIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQ-NSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSST-----RIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIRVSXXXXXXXXXXGESVLS-IDTIRDLTQQIIDCPRNHNLIHG 2816
            +++A    D+ VR+  F+++C+            +  I+  L  NL+  +   RQ  V+  ++L+N ++       R+  DS + V           EFL  L +YL   L+P A+F +R + L +L L+   F   + F       +  +   +TL+Y   DT+E N+  + K      I ++ T+   D +++L + +L  ++++ P D   A  +   ++  + +   LL H++        + +LE    SI SN   F               IA +S        P Y  L C+R ++ E  F+ +    SV         +ISL   +  V+ P  S A+PEG LP     D +  L             S  VES    PE                  L +CCWR+ KE+SL+ G I+  + V+  +D      N  QV+ I D+F DQ+ SV HKGAFE    GF KLC+ LWRS  +E+ E+P +++     +I  +  +++   TRRSAGLP +   ++ SEP +    SS  F  + ++S+L  A +Q ++ +   ++H  NI R LF++S L   LI     A+  S+  F S+ W +RNS+ LL+ AL+ RIFG S       K NRL  + FF+ Y+ +Y F+ + +K+C  + +N N  +      +YPIL++LGRL P     +S    LT     +     S +W +RV AA+A+  L   E+  S + ++ D   Q      +HN IHG
Sbjct:  549 LQKALTHADDQVRLSAFSMICESPKTTEVVLENAFKLIMELLPYNLNCQAPAFRQQLVSHLKKLLNRMVDSKNAFPRKKADSPELVDFFTSVENAYEEFLKWLKKYLYSCLFPGANFPRRVTVLNLLLLLHKYFPETLSF-------SGTLEETQTLLYALQDTYENNKQISLKILQSVDISILATED-EDCFKTLLETSLILASSTKPPDTVTAAYMFAFMVKSKNFDTVLLNHLLVSMENGPCLLQLEKDSLSIVSNSSAFIGLLLLSCELLKHLKIAQDSLCDAAACAPIYGVLACIRSIISEIDFKTLDDNFSVREWANLIRELISLGIQVAKVVEPVVSHASPEGHLPMDPDSDSISKLQATVRRSIGKRFQSAVVESEDFVPESDQVVLDKVKTHAVSAQILLLCCWRTHKEVSLLFGEISDRIPVSGDNDTESGILNVTQVKDIGDYFMDQMASVQHKGAFEQAYIGFTKLCKMLWRSPILELQELPQNWLNDLCLAIKGLKDDKNFSYTRRSAGLPFIMQAILASEPGI----SSSLFFKNTISSLLSMASTQKDNGNVDEMVHALNILRALFRDSCLSDVLIPFVSEALMASIIGFKSHYWIVRNSSHLLFSALMTRIFGVSGPQDEVGKKNRLTGRTFFSYYKEIYAFLYDELKQC-AAVMNQNRESLTLVPSLYPILLVLGRLYPAPGECDSR---LTSFIPFLNVCSGSPIWKVRVLAAQALVPLISAENFSSTLQSLFDYLPQNGQIITSHNQIHG 1301
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BLAST of Thyroid adenoma-associated-like protein vs. TrEMBL
Match: A0A2C9L3N9 (DUF2428 domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106056962 PE=4 SV=1)

HSP 1 Score: 230.335 bits (586), Expect = 5.617e-57
Identity = 217/843 (25.74%), Postives = 390/843 (46.26%), Query Frame = 3 
Query:  684 REINGNRILCIEMLWKKSFSDGI*WR*IELEKKIDSVTRERILGSVLNEGFVEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVN------GIIRQNIDSSQAVS---------TEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGII-FDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCF-IILVNTKPLVDHYE--SLKQIALEKSNTSNPHDCAVA-----------------FTIMKTL-----LGIEEYKLLPHVIADQLIARLECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDE-HFENISSQLS------VTRIISLCYAINDVIFPFNSSAAPEGCLPDEVRN--LLDSH----------------------FVESHPEYLTICCWRSCKEISLILG--------NIAAELVNKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNED---LCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILV--KADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFG--PSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTR------IYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIRVSXXXXXXXXXXGESVLSIDTIRDLTQQIIDCPRNH---NLIHGSIKAIRCIFEDL--LDNLFISDNQWALLRGISAEIW 2918
            R   G  I+C+    +K+ + G+       + K +S+ ++ +    L+   ++ A   +D+ VR++ F +LC+        ++  +  +  F+  NL+  S   RQ F++  ++  +        +R+++  +Q  +          +F   L  YL  +LYP ++F +R++ LA+L+L+ N F S  + F +  +   +++   + L+   +DTFEEN+  A     + +    PL +  +   + +I++  + ++ P DC  A                 FT+ +TL       I    L   V+    +       E   +N  L   A   P Y +L C+RY++ E +++ + S+        +  +I  C  +  ++ P   +++PEG +P+ V N   LD                         VES PEYL +CCWRS KE+SL LG        N+  E    S   F+QV+ I D+F +Q+    H+GAFE    GF+ +CQ LW         +P+ ++ + +  I + +     C TRRSAG+P     + ++EP V   R   +  M+ L ++ V  + + + +  Q   IH  NI R L++++ L   ++ +    +K SV  F S +W +RNSATLL  +L+ RIFG   SK     +K N  + + FF++Y ++Y F+++ +K       N++SS +      +YP+L++LGRL P       ++  L+     + +  SS V+  R+ A+ A+  L     V+SI   + L   I +    H   +LIHGS+  +  I + L  LD+    D    +L  +S   W
Sbjct:  546 RASCGAVIMCL----RKARTLGL------FKAKQESIEKQPLWYGYLHPDVLKSALCSFDQQVRLDAFGLLCENHKTTEPVSHFEFTMLKFFIPCNLNNQSPAFRQSFLSLSKKFFSRSKESLATMRKHLSKNQKHADFDETIQNYQKFYTWLTNYLLSSLYPGSAFARRTTSLAMLSLLTNIFGSDCVEFSVTRLLSHQHI---QVLLECISDTFEENKKEAFNILSVYMQQAGPLWNQNQLNHIFEISMMLACSTRPQDCETAVYNFLLILKQQELHADIFTLPETLNIVNGAPIRNTGLKHPVLNLLNVLLDLLDDEICVANQSLITAAATRPMYPTLLCIRYIMPELNYQLLESEYIPFAKNFILHLIQSCQNLAKIVSPVVQNSSPEGNMPENVLNSSTLDMSDLFNIESIGPVLSESTVKESQILVESMPEYLVVCCWRSIKEVSLTLGKLCLQVPVNLITEHETLSLLTFDQVKMIGDYFSEQLLESIHRGAFELAYAGFQLMCQMLWSHPLASFNHLPIQWLTQVMLDIKSEDSGSKFCITRRSAGIPFFIQAITSTEP-VTAGRKCFHQVMNDLLALAVIEEGEEKQTKYQDSQIHAVNILRALYRDARLGEDVLPYVADGLKASVLGFKSELWAIRNSATLLLSSLMTRIFGVKRSKDETDISKKNCQSGRTFFHQYPSLYTFLLSELKAATD---NIHSSDKLQLHPSLYPVLLVLGRLYPSTIDNPDTNMSLSAFIPFVIKCASSPVYKTRIIASLALLPLVRRNEVISIS--QTLLANIPESYNQHISNSLIHGSLLQLCQIMKLLPSLDSATKEDYLNFMLSNLSKRTW 1369
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000012404.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000027.1:248023:283669:1 gene:ENSAMXG00000012066.2 transcript:ENSAMXT00000012404.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 129.028 bits (323), Expect = 2.320e-29
Identity = 121/490 (24.69%), Postives = 216/490 (44.08%), Query Frame = 3 
Query: 1656 SLCYAINDVIFPFNSSAAPEGCLPDEV-RNLLDSHFVESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDN-----FNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRIIHIFNIS-----RLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIK----ECDKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIRV-SXXXXXXXXXXGESVLSIDTIRDLTQQIIDCPRNHNLIHGSIKAIRCIFEDLLDNLFISDNQWALLRGISAEIWNRLSPVILSLRTDSRCP---QEFIDLIEFIHGKSSKFLEQINFNSYLTEITSL 3068
            S C   N +      S A E  L +E   N+L S   E H   LT CCW + KEI + LG++   +++ S  N        +   +  F D I    H GA E  C GF K C +L  S   E+ EIP   +++ + ++ +      TRR+AGLP L L ++ +E    +  SS       +N++L  A +    D  + + +  +      + L K SSL   ++ +  +    S+   SS  W +RN+A  LY +L  R+ G     +  +    ++   FF+ Y  +  F+   ++    +  +S L+L+ S  +YP+L +L +L P        +  L+   H + +  +S V+ +RV S+   +A +   E + S+  +     +  + P  HN +HG +  I  +       L  S +   ++ G+ A +W   S        D RC    QE++ ++        + L +I   ++L+ + S+
Sbjct:  920 SFCDMGNAISSLIGQSGAGEAGLDEEGDENVLLS---EEHSLVLT-CCWVTLKEIGIFLGSLVERILSVSCKNTPLLTVKDLHGASRVFKDIILKCRHWGAVEGCCIGFTKFCAALLGSPDPELREIPSRMLQQGLTVLQSPRATSVTRRAAGLPMLILGVLAAE----ENSSSRPLLALSVNTLLETARTPLPPDWDQTLDLPQVCAVHTLQTLVKGSSLGLSILQYAPAVAMLSLTLLSSPCWAMRNAALQLYSSLCSRMLGQRPAGEDVSAQYAMSPPAFFSHYPALQPFLQEALERAAADLHESRLSLHPS--LYPVLTLLAKLQP---GAQEQTRALSAFLHPLLQLAASPVYAVRVMSSRALVAMIPPAEYLASVVRMVGDLPESPESPCRHNRVHGQLLQINTV-------LLCSSSLRPVVEGLEARLWLGSS--------DQRCALVRQEYVSVL--------RLLRKICSETFLSRLCSV 1373
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Yeast
Match: TRM732 (Protein involved in 2'-O-methylation of C32 of substrate tRNAs; interacts with 2'-O-ribose methyltransferase Trm7p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; non-essential gene; yeast null mutant can be functionally complemented by human THADA, mutations in which have been implicated in epithelial thyroid adenomas, type 2 diabetes, and polycystic ovary syndrome (PCOS) [Source:SGD;Acc:S000004872])

HSP 1 Score: 67.0106 bits (162), Expect = 2.301e-11
Identity = 68/276 (24.64%), Postives = 121/276 (43.84%), Query Frame = 3 
Query: 1707 APEGCLPDEVRNL-LDSHFVESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLCS--TRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSI--LVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNR-LNSKVFFNRYQNMYEFIVNTI 2516
            +  G LP++  N  +    + SH        +R+ KE S +L  I    + K     +Q+  I D F  Q++++ H GAF+++  G +  C           +E P          + + +      TRRS GLP L   ++++E  V K R  L    + L  +  L     Q+  D  ++  I N    +F E  L     +    A++ ++  F  +IW LRN + +L+ +L  RIFG         K  R +++K+FF +Y  + + ++N +
Sbjct:  638 SAHGILPEKYANCGVPDQVIISH-------AFRAIKEASYLLETI----LKKYPLTRDQLDSIGDLFIVQLSTIRHSGAFQAVLPGLKAFCIRCQ-------LEFPAILEELLSKSVKSLKSKTQHITRRSGGLPFLVTTVLSAE--VTKGRPLLQKTFENLLLVARLPIPPHQDEFDLPQVNAI-NCINAIFVEPKLSVHCTSFVSEALELALLNFDCDIWALRNCSIMLFTSLQNRIFG---------KVGRSVSAKLFFTKYSGLRQLLLNIL 883
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Nematostella
Match: EDO39110 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB36])

HSP 1 Score: 172.94 bits (437), Expect = 8.583e-44
Identity = 170/690 (24.64%), Postives = 306/690 (44.35%), Query Frame = 3 
Query:  807 ILGSVLNEGFVEEASVDWDENVRMEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNC-------FRQLVNGIIRQNIDSSQAVS---------TEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSF-DSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLKQIALEKSN-TSNPH--DCAVAFTIMKTLLGIEEYKLLPHVIAD---------QLIARLECSLESIKS-----NIELFHIAMNSPFYSSLYCLRYLLDE-HFENISSQLS----VTRIISLCYAINDVIFPFNSSAAPEGCLPDEV--RNLLDSHFV-ESHP---------------------------------EYLTICCWRSCKEISLILGNIAAELVNKSSD-NFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHT---NEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTR----IYPILVILGRLVP-ELDHFNSS 2624
            + G V++   +++A    D+  R++   +LC         +      +  FL  N++  S   RQ             R+ V   +R N+D  + +          T FL      L  +L+P ASF + ++ L  L L+ + F DS   +      D  +   ++ L+  F+DT++ N+  A                 ESL+ + L      ++P   D + A   +K L+      L P    +         Q  + L   L ++ S     N  L   A  +P + +++CLR LL   +  N+ S  S    V+R+++  + + +++FP  +S++PEG + D+    NLL      ++ P                                 + L +CCWR+ KE++L+LG++   + + S     +QV++I DFF   + +  H+GAFE    GF KLC+ LWR    ++  +P++++   +  I T   ++ L  TRRSAG+P    V+  S P        L+        +       +S  Q   +H  NI R L++++ L   +       +  S+  F+S+ W +RNS+TLL+ AL+ R+FG +K    H++ N +  + FF+RY +M+ F++  +++  +  LN   S      +YP+LV+L RL P  +D  +S+
Sbjct:  227 VWGGVVSVDVLQKALCHTDDQCRLDALGLLCDSPRTTESVSVTDMRLLKTFLQLNINSQSPSFRQQSAALLKKLLLRMREGVRLSVR-NLDRDKNIELHKYKLHAYTRFLQWYSNLLFSSLFPGASFARLTTSLHGLKLLASIFTDSDSKYGSFHFHDVMHPCNIRGLMKCFSDTYDVNKQLAYDLLTSCPRDFLPFQSAESLEPLLLMVEQLVTSPRAVDASTASVYLKILVDRCMVPLYPESATEISDNPLNQRQAFSVLSALLSTLTSQASVANESLVLAAARAPMHGAVFCLRTLLTHVNLRNVESAGSWKHLVSRLLTELFVVAELVFPVVTSSSPEGHVIDDSINGNLLSYALTSKARPCNTITKTPVSPATNSKLHYFLFKMMFPVFTPSSQALLVCCWRTMKEVALLLGDLVQNISDDSGLLTADQVKRIGDFFTAVLLTSKHRGAFELAYTGFMKLCEVLWRCRDADLRGLPLAWLDGLMSDISTTVPSDFLSGTRRSAGVPFFVQVVKQSSPASLCSLCLLDLLHAASLPVEPSLPQDSSLPQ---VHSRNIIRALYRDTRLGEDVSPFVADGLIASISGFTSSSWAVRNSSTLLFSALVTRVFGVAKAKDDHSRRNCMTGREFFSRYPSMHPFLLKHLEKATEF-LNREESVTLHPCLYPVLVLLSRLYPSSMDGVDST 911
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Medaka
Match: si:ch211-225b11.4 (thyroid adenoma-associated protein homolog [Source:NCBI gene;Acc:105354731])

HSP 1 Score: 107.071 bits (266), Expect = 1.153e-22
Identity = 107/424 (25.24%), Postives = 180/424 (42.45%), Query Frame = 3 
Query: 1764 ESHPEYLTICCWRSCKEISLILGNIAAE--LVNKSSDNFN----QVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQL-----NSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNR-LNSKVFFNRYQNMYEFIVNTIKECDK------SPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIRVSXXXXXXXXXXGESVLSIDTIRDLTQQIIDCPRN---HNLIHGSIKAIRCIFED-LLDNLFISDNQWALLRGISAEIWNRLSPVILSLRTDSRCP 2969
            E H   LT CCW S KEI + LG +  +    +K S   N     + +++  F + + +  H GA E  C GF K C  L   S  E+ EIP   + + + ++        TRR+AGLP L L ++ +E   +K R  L  ++  L       +L   D      Q   +H       L + + L   +          S+   SS  W +RN+A  LY +L  R+ G     +        +    F   Y+ +  F++  +    K      +   L+    ++PIL +L +L P +   +    D +   H + +  +S ++ +RV A+KA+ A+      ++I  +  LT Q+   P++   HN +HG +  I+ I E  L  N  ISD +W        E+ +R+      +    RCP
Sbjct:  979 EEHRLVLT-CCWVSLKEIGIFLGTLVEKGFTESKQSGEHNLLKPHLSRVSKVFKNILLNCRHWGAIEGCCVGFTKFCSCLLSCSDPELKEIPAQMLTQGLQVVQCPRSASVTRRAAGLPMLILSILAAED-ASKARPLLALSVQTLMDTARTPVLDNWDQTLDLPQVCAVHTLQA---LVRAAPLAAAVRQFASGITVLSLTLLSSTCWAMRNAALQLYSSLCFRMLGQKSGNEESGAVQHGMTPPAFLFHYRQLQPFLLGELTRAAKGLRGPSAEAKLHLQPSLFPILTLLAQLQPAVTDTSGVFLDFS---HPLLQLSASPIYSVRVMASKALVAMTPTSEHMNI--LLQLTAQLPG-PQDICSHNQLHGRLLQIKAILEKCLCTNSRISD-EW-------REVVSRVQDAQWLVTESQRCP 1383
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BLAST of Thyroid adenoma-associated-like protein vs. Planmine SMEST
Match: SMESG000023235.1 (SMESG000023235.1)

HSP 1 Score: 2112.04 bits (5471), Expect = 0.000e+0
Identity = 1051/1065 (98.69%), Postives = 1058/1065 (99.34%), Query Frame = 3 
Query:  876 MEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLLPHVIADQLIARLECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLPDEVRNLLDSHFVESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIRVSXXXXXXXXXXGESVLSIDTIRDLTQQIIDCPRNHNLIHGSIKAIRCIFEDLLDNLFISDNQWALLRGISAEIWNRLSPVILSLRTDSRCPQEFIDLIEFIHGKSSKFLEQINFNSYLTEITSLWQVKLLFIALESNRIDEDMKYVKGISIGALQNAEYKIRKEMLIKLSLNPEIINKIFPRFDIDLIFHLACSESHPSVDLLCYRFLDQFISAHEISSHSFTQMLSVLIGILQCQSSIRTKKFCILLELVGSILHRWIPSDSSTSNQQVCEYLESYLQLISANSKYETDVEIRISCAESLRRCLQNADWRDYYHGNNTFIEIAITQLSDENDHIRNLAALSVAIVLQMPSLRSIVPSAVLSKYFKLIICGSQSNSVRILSDLSPIGYQIGNVKYSQGKISVFDSEEINFYYDFYDVHSDLKLDLNQGNEFLYRSSFQEILLGTSKFSSAYQNKLLNR 4070
            M MFAILCKEISRQNQ NYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLKQIALEKSNTSNPHDC+VAFTIMKTLLGIEEYKLLPHVIA+QLIARLECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLPDEVRNLLDSHFVESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKA+SQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLT++KHKIQRYLSSSVWVIRVSAAKAIAALALGESVLSIDTIRDLTQQIIDCPRNHNLIHGSIKAIRCIFEDLLDNLFISDNQWALLRGISAEIWNRL PVILSLRTDSRCPQEFIDLIEFIHGKSSKFLEQINFNS LTEITSLWQVKLLFIAL+SNRIDEDMKYVKGISIGALQNAEYKIRKEM IKLSLNPEIINKIFPR DIDLIFHLACSESHPSVDLLCYRFLDQFISAHEISSHSFTQMLSVLIGILQCQSSIRTKKFCILLELVGSILHRWIPSDSSTSNQQV EYLESYLQLISANSKYETDVEIRISCAESLRRCLQNADWRDYYHGNNTFIEIAITQLSDENDHIRNLAALSVAIVLQMPSLRSIVPSAVLSKYFKLIICGSQSNSVRILSDLSPIGYQIGNVKYSQGKISVFDSEEINFYYDFYDVHSDLKLDLNQGNEFLYRSSF+EILLGTSKFSSAYQNKLLNR
Sbjct:    1 MGMFAILCKEISRQNQHNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLKQIALEKSNTSNPHDCSVAFTIMKTLLGIEEYKLLPHVIAEQLIARLECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLPDEVRNLLDSHFVESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKANSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLTFVKHKIQRYLSSSVWVIRVSAAKAIAALALGESVLSIDTIRDLTQQIIDCPRNHNLIHGSIKAIRCIFEDLLDNLFISDNQWALLRGISAEIWNRLRPVILSLRTDSRCPQEFIDLIEFIHGKSSKFLEQINFNSNLTEITSLWQVKLLFIALKSNRIDEDMKYVKGISIGALQNAEYKIRKEMFIKLSLNPEIINKIFPRSDIDLIFHLACSESHPSVDLLCYRFLDQFISAHEISSHSFTQMLSVLIGILQCQSSIRTKKFCILLELVGSILHRWIPSDSSTSNQQVSEYLESYLQLISANSKYETDVEIRISCAESLRRCLQNADWRDYYHGNNTFIEIAITQLSDENDHIRNLAALSVAIVLQMPSLRSIVPSAVLSKYFKLIICGSQSNSVRILSDLSPIGYQIGNVKYSQGKISVFDSEEINFYYDFYDVHSDLKLDLNQGNEFLYRSSFREILLGTSKFSSAYQNKLLNR 1065
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Planmine SMEST
Match: SMESG000023235.1 (SMESG000023235.1)

HSP 1 Score: 2077.37 bits (5381), Expect = 0.000e+0
Identity = 1036/1059 (97.83%), Postives = 1046/1059 (98.77%), Query Frame = 3 
Query:  894 LCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLLPHVIADQLIARLECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLPDEVRNLLDSHFVESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIRVSXXXXXXXXXXGESVLSIDTIRDLTQQIIDCPRNHNLIHGSIKAIRCIFEDLLDNLFISDNQWALLRGISAEIWNRLSPVILSLRTDSRCPQEFIDLIEFIHGKSSKFLEQINFNSYLTEITSLWQVKLLFIALESNRIDEDMKYVKGISIGALQNAEYKIRKEMLIKLSLNPEIINKIFPRFDIDLIFHLACSESHPSVDLLCYRFLDQFISAHEISSHSFTQMLSVLIGILQCQSSIRTKKFCILLELVGSILHRWIPSDSSTSNQQVCEYLESYLQLISANSKYETDVEIRISCAESLRRCLQNADWRDYYHGNNTFIEIAITQLSDENDHIRNLAALSVAIVLQMPSLRSIVPSAVLSKYFKLIICGSQSNSVRILSDLSPIGYQIGNVKYSQGKISVFDSEEINFYYDFYDVHSDLKLDLNQGNEFLYRSSFQEILLGTSKFSSAYQNKLLNR 4070
            L K+  R   + + LWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLKQIALEKSNTSNPHDC+VAFTIMKTLLGIEEYKLLPHVIA+QLIARLECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLPDEVRNLLDSHFVESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKA+SQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLT++KHKIQRYLSSSVWVIRVSAAKAIAALALGESVLSIDTIRDLTQQIIDCPRNHNLIHGSIKAIRCIFEDLLDNLFISDNQWALLRGISAEIWNRL PVILSLRTDSRCPQEFIDLIEFIHGKSSKFLEQINFNS LTEITSLWQVKLLFIAL+SNRIDEDMKYVKGISIGALQNAEYKIRKEM IKLSLNPEIINKIFPR DIDLIFHLACSESHPSVDLLCYRFLDQFISAHEISSHSFTQMLSVLIGILQCQSSIRTKKFCILLELVGSILHRWIPSDSSTSNQQV EYLESYLQLISANSKYETDVEIRISCAESLRRCLQNADWRDYYHGNNTFIEIAITQLSDENDHIRNLAALSVAIVLQMPSLRSIVPSAVLSKYFKLIICGSQSNSVRILSDLSPIGYQIGNVKYSQGKISVFDSEEINFYYDFYDVHSDLKLDLNQGNEFLYRSSF+EILLGTSKFSSAYQNKLLNR
Sbjct:  433 LKKKSIRLRGKGFWLWNQILRFLISNLSIASNKLRQHFVNCFRQLVNGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNLIFNSFDSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIILVNTKPLVDHYESLKQIALEKSNTSNPHDCSVAFTIMKTLLGIEEYKLLPHVIAEQLIARLECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENISSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLPDEVRNLLDSHFVESHPEYLTICCWRSCKEISLILGNIAAELVNKSSDNFNQVQQIADFFFDQITSVTHKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLCSTRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKANSQNSADQKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKECDKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLTFVKHKIQRYLSSSVWVIRVSAAKAIAALALGESVLSIDTIRDLTQQIIDCPRNHNLIHGSIKAIRCIFEDLLDNLFISDNQWALLRGISAEIWNRLRPVILSLRTDSRCPQEFIDLIEFIHGKSSKFLEQINFNSNLTEITSLWQVKLLFIALKSNRIDEDMKYVKGISIGALQNAEYKIRKEMFIKLSLNPEIINKIFPRSDIDLIFHLACSESHPSVDLLCYRFLDQFISAHEISSHSFTQMLSVLIGILQCQSSIRTKKFCILLELVGSILHRWIPSDSSTSNQQVSEYLESYLQLISANSKYETDVEIRISCAESLRRCLQNADWRDYYHGNNTFIEIAITQLSDENDHIRNLAALSVAIVLQMPSLRSIVPSAVLSKYFKLIICGSQSNSVRILSDLSPIGYQIGNVKYSQGKISVFDSEEINFYYDFYDVHSDLKLDLNQGNEFLYRSSFREILLGTSKFSSAYQNKLLNR 1491

HSP 2 Score: 502.286 bits (1292), Expect = 1.671e-152
Identity = 269/272 (98.90%), Postives = 270/272 (99.26%), Query Frame = 1 
Query:    1 LYLAILSSFSXXXXXXXXXXXXXXXXXXRKSPRNYDESILKSMFFRKLCDIISINKEHEKTMEISEYLIDHAFDQQFIKQTSIRNNTTSVLSSGLSIHLNKCQKCSRTVLCRELFQRLLKLFQQSWNVSGKFSFINIFIRVFSGEVIRKIEPKIELILLQTAQEYSLSTYACDSYISLLTASNNSSIGIELIVEIFHRENPETSFSNIDSIRKTICEYFVPKLTQENCGKLTEIVFYALKCYGKSRFPMEFSGDRSSLKKKSIRLRGKGFWV 816
            LYLAILSSFSFLNLIENNYLINLIEFINRKSPRNYDESILKSMFFRKLCDIISINKEHEKTMEISEYLIDHAFDQQFIKQTSIRNNTTSVLSSGLSIHLNKCQKCSRTVLCRELFQRLLKLFQQSWNVSGKFSFINIFIRVFSGEVIRKIEPKIELILLQTAQEYSLSTYACDSYISLLTASNNSSIGIELIVEIFHRENPETSFSNID IRKTICEYFVPKLTQENCGKLTEIVF ALKCYGKSRFPMEFSGDRSSLKKKSIRLRGKGFW+
Sbjct:  176 LYLAILSSFSFLNLIENNYLINLIEFINRKSPRNYDESILKSMFFRKLCDIISINKEHEKTMEISEYLIDHAFDQQFIKQTSIRNNTTSVLSSGLSIHLNKCQKCSRTVLCRELFQRLLKLFQQSWNVSGKFSFINIFIRVFSGEVIRKIEPKIELILLQTAQEYSLSTYACDSYISLLTASNNSSIGIELIVEIFHRENPETSFSNIDLIRKTICEYFVPKLTQENCGKLTEIVFCALKCYGKSRFPMEFSGDRSSLKKKSIRLRGKGFWL 447
[Close]
BLAST of Thyroid adenoma-associated-like protein vs. Planmine SMEST
Match: SMESG000032327.1 (SMESG000032327.1)

HSP 1 Score: 51.6026 bits (122), Expect = 5.387e-6
Identity = 57/214 (26.64%), Postives = 98/214 (45.79%), Query Frame = 3 
Query: 2079 TRRSAGLPHLFLVLITSEPLVNKQRSSL---NFAMDQLNSILVKADSQNSAD---QKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSATLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIK-EC--DKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSSSVWVIR 2693
            TRRSAGLP   L+L+++    N   S     N  + QL  +  K D+ N  +      I+H  N+ + +    +L   L  H    +  +++ FSS+ W +RN+A  L+ A++ R+   +K +  +  F+ +     F+ Y  ++  I+N +K  C  D S   + + T + P L  L  L+   D        L+ L       L+S V V+R
Sbjct:  888 TRRSAGLP---LILMSALNGSNDNSSGSVLPNECLIQLMDLCNKLDNANDVNGWCDPPIVHYLNLVKQMCSNPALQVPLQRHFGRIILITLKHFSSSNWGVRNAALQLFMAMLSRVASATKGVASNPTFSEV-----FSLYPELWNPILNILKLSCIKDDSKSFVKNQTLV-PTLTFLSNLLYSADKQLPQGMSLSDLLSCFWPLLTSPVVVVR 1092
The following BLAST results are available for this feature:
BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
THADA4.793e-3333.85THADA armadillo repeat containing [Source:HGNC Sym... [more]
THADA4.793e-3333.85THADA armadillo repeat containing [Source:HGNC Sym... [more]
THADA4.111e-2934.34THADA armadillo repeat containing [Source:HGNC Sym... [more]
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Y92H12A.51.852e-3329.06pep chromosome:WBcel235:I:1490887:1514411:-1 gene:... [more]
Y92H12A.51.913e-3329.06pep chromosome:WBcel235:I:1491340:1514411:-1 gene:... [more]
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
THADA1.197e-3024.49gene:FBgn0031077 transcript:FBtr0289978[more]
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
thada9.845e-4723.60THADA armadillo repeat containing [Source:ZFIN;Acc... [more]
thada1.917e-3827.45THADA armadillo repeat containing [Source:ZFIN;Acc... [more]
thada2.590e-3827.45THADA armadillo repeat containing [Source:ZFIN;Acc... [more]
si:ch211-225b11.44.150e-2524.94si:ch211-225b11.4 [Source:ZFIN;Acc:ZDB-GENE-060526... [more]
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pxn7.793e-4123.09paxillin [Source:Xenbase;Acc:XB-GENE-941407][more]
pxn7.340e-4023.13paxillin [Source:Xenbase;Acc:XB-GENE-941407][more]
pxn2.029e-3923.00paxillin [Source:Xenbase;Acc:XB-GENE-941407][more]
pxn3.831e-3923.14paxillin [Source:Xenbase;Acc:XB-GENE-941407][more]
pxn2.658e-3623.30paxillin [Source:Xenbase;Acc:XB-GENE-941407][more]
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Thada1.494e-3424.00thyroid adenoma associated [Source:MGI Symbol;Acc:... [more]
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BLAST of Thyroid adenoma-associated-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A8C750|THADA_CANLF9.753e-3924.89Thyroid adenoma-associated protein homolog OS=Cani... [more]
sp|A8C754|THADA_CHICK1.870e-3424.29Thyroid adenoma-associated protein homolog OS=Gall... [more]
sp|A8C756|THADA_MOUSE1.045e-3324.00Thyroid adenoma-associated protein homolog OS=Mus ... [more]
sp|Q6YHU6|THADA_HUMAN2.302e-3233.85Thyroid adenoma-associated protein OS=Homo sapiens... [more]
sp|A8C752|THADA_CHLAE2.397e-3133.20Thyroid adenoma-associated protein homolog OS=Chlo... [more]
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BLAST of Thyroid adenoma-associated-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A210QPQ67.124e-5927.41Thyroid adenoma-associated protein-like OS=Mizuhop... [more]
A0A433TA358.958e-5827.87DUF2428 domain-containing protein OS=Elysia chloro... [more]
A0A4Y2E5D43.222e-5729.00Thyroid adenoma-associated OS=Araneus ventricosus ... [more]
A0A4Y2E4B33.251e-5728.87Thyroid adenoma-associated OS=Araneus ventricosus ... [more]
A0A2C9L3N95.617e-5725.74DUF2428 domain-containing protein OS=Biomphalaria ... [more]
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSAMXT00000012404.22.320e-2924.69pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
TRM7322.301e-1124.64Protein involved in 2'-O-methylation of C32 of sub... [more]
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO391108.583e-4424.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Thyroid adenoma-associated-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
si:ch211-225b11.41.153e-2225.24thyroid adenoma-associated protein homolog [Source... [more]
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BLAST of Thyroid adenoma-associated-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000023235.10.000e+098.69SMESG000023235.1[more]
SMESG000023235.11.671e-15297.83SMESG000023235.1[more]
SMESG000032327.15.387e-626.64SMESG000032327.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023155 ID=SMED30023155|Name=Thyroid adenoma-associated-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=4372bp
CTGTATTTAGCGATATTGAGTTCATTTTCCTTTTTGAATTTAATAGAAAA
TAATTATTTAATAAATCTAATTGAATTTATTAATCGAAAATCTCCTCGAA
ATTATGACGAATCCATTTTAAAATCGATGTTTTTTCGAAAGTTATGCGAC
ATTATTTCAATAAATAAAGAACATGAAAAAACAATGGAAATATCGGAATA
TCTAATCGACCACGCTTTTGATCAGCAATTCATCAAACAGACTTCAATAC
GAAACAATACAACATCGGTTTTGTCATCAGGCCTGTCGATTCATTTGAAT
AAATGCCAGAAATGCAGTCGGACGGTTTTGTGTCGGGAATTATTTCAACG
ACTTTTAAAACTCTTCCAACAGTCGTGGAATGTTTCGGGGAAATTTTCAT
TCATCAACATTTTCATCCGAGTGTTCTCCGGTGAAGTTATTAGAAAAATC
GAGCCGAAAATTGAATTAATCCTCCTACAAACCGCTCAGGAATATTCGCT
TTCCACTTATGCTTGCGACAGTTACATTTCTCTGTTGACAGCGAGCAACA
ATTCATCGATTGGAATAGAATTAATCGTCGAGATTTTCCACCGAGAAAAC
CCCGAAACTTCTTTCTCGAATATCGACTCGATTCGTAAAACGATTTGCGA
ATATTTCGTCCCGAAATTGACTCAGGAAAATTGCGGGAAATTAACGGAAA
TCGTATTTTATGCATTGAAATGCTATGGAAAAAGTCGTTTTCCGATGGAA
TTTAGTGGAGATAGATCGAGCTTGAAAAAAAAATCGATTCGGTTACGCGG
GAAAGGATTTTGGGTTCGGTGTTGAATGAGGGATTTGTTGAGGAGGCCTC
TGTGGATTGGGATGAAAATGTACGAATGGAAATGTTTGCTATTCTATGCA
AAGAAATATCCCGGCAAAACCAACGCAATTATCAGCTGTGGAATCAGATT
TTGAGGTTTCTGATAAGTAACCTATCGATTGCTTCCAATAAACTCCGGCA
ACATTTTGTCAACTGTTTCCGACAGTTAGTCAACGGGATTATTCGACAAA
ATATCGATAGTTCTCAGGCGGTTTCAACGGAATTTCTCGCGAAGTTGTTG
AGATATCTTTCTCGTAATCTTTATCCAATCGCATCGTTCTATAAGCGAAG
TTCTTTTCTCGCGGTTCTTAATTTGATTTTTAACTCGTTTGACAGTGGAA
TAATTTTCGACCTGCTGGACATGAGTGATGCCGAATATGTCATTTTCTTG
AAAACTCTCGTTTATTTCTTCGCCGATACATTTGAAGAAAATCGAATGAA
CGCTTCTAAATGCTTCATTATCTTGGTAAACACAAAACCGCTTGTTGATC
ATTACGAATCTCTTAAACAAATTGCACTTGAGAAGAGTAACACCAGTAAT
CCACACGACTGTGCAGTGGCTTTTACGATAATGAAAACCCTGTTAGGTAT
CGAGGAATATAAATTGTTACCCCATGTAATCGCTGATCAATTGATTGCTC
GTTTGGAGTGCAGTTTGGAAAGCATAAAATCCAACATTGAACTATTCCAC
ATCGCTATGAATTCACCGTTCTATTCCTCCTTATACTGCTTGAGATATCT
ACTTGATGAGCACTTCGAAAATATCAGTTCCCAATTGTCTGTAACAAGAA
TCATTTCGCTTTGCTATGCGATAAATGACGTAATATTCCCTTTCAATTCA
TCTGCAGCCCCCGAGGGATGTCTGCCAGATGAAGTTCGTAATTTATTAGA
TTCTCATTTTGTTGAATCTCACCCTGAATATCTTACGATTTGCTGCTGGA
GAAGTTGTAAAGAAATTTCTCTCATTCTCGGTAACATTGCAGCTGAGTTA
GTTAATAAGTCTTCGGATAATTTTAATCAGGTGCAACAAATCGCTGACTT
CTTTTTTGATCAAATAACTTCCGTTACTCATAAAGGAGCTTTTGAATCTT
TATGTGGAGGATTTGAAAAGTTGTGTCAATCATTGTGGAGATCATCAACA
ATGGAAATTGTTGAGATTCCTATGAGTTTCATTAGAAAATCAATAGATAT
CATTCATACAAATGAAGATCTGTGTTCGACTCGACGATCAGCTGGATTGC
CGCATCTTTTTCTGGTGTTGATAACATCTGAACCGTTGGTAAATAAGCAG
AGATCGTCTTTAAACTTTGCAATGGACCAACTAAACTCGATTTTAGTAAA
AGCGGATTCTCAGAACTCTGCCGATCAAAAGCGAATAATTCACATATTTA
ATATCTCTCGACTGTTGTTTAAGGAATCTAGTTTGCTTACTCAATTGATC
AATCATACCTTTTCTGCTGTAAAATATTCTGTACAATTCTTTTCCTCAAA
TATATGGCCTTTACGAAACTCTGCAACCTTGCTGTATTGTGCTTTGATTG
AACGCATTTTCGGGCCGAGTAAAACCATTAAGTTTCACAATAAATTCAAT
AGACTGAATAGCAAAGTGTTCTTTAACCGCTACCAAAACATGTATGAATT
TATCGTTAACACCATCAAGGAATGCGATAAATCTCCCCTGAATTTAAACT
CCTCCACAAGAATCTATCCGATCTTGGTCATTTTAGGTCGATTGGTTCCA
GAATTGGACCATTTTAATAGCTCTTCATACGATTTGACATATTTAAAGCA
CAAAATCCAAAGGTATTTAAGTTCCAGTGTTTGGGTTATCAGGGTGTCGG
CTGCGAAAGCAATTGCTGCCTTGGCATTGGGAGAATCGGTGCTGTCGATC
GATACTATTAGGGATTTGACTCAACAGATTATCGATTGTCCCAGAAATCA
CAATCTCATTCATGGATCGATTAAAGCGATTCGTTGCATTTTCGAAGATC
TTTTGGATAATCTTTTCATTTCCGATAACCAATGGGCATTACTGAGAGGC
ATCAGTGCTGAAATATGGAATCGATTGAGTCCCGTAATTCTGTCACTGCG
AACGGATTCTCGGTGTCCACAAGAATTTATCGATTTGATTGAATTCATTC
ATGGAAAATCTTCGAAATTTTTGGAACAAATTAATTTCAATTCTTATTTA
ACGGAAATTACTTCATTGTGGCAAGTGAAGCTGTTATTTATTGCTTTGGA
GTCGAACAGAATTGATGAGGACATGAAATACGTGAAAGGAATATCGATAG
GAGCCTTGCAGAATGCAGAATATAAAATTCGCAAAGAAATGCTTATAAAG
CTCTCACTGAACCCTGAAATCATCAATAAAATATTCCCAAGATTTGATAT
TGATCTGATATTCCACCTGGCGTGCAGTGAATCTCATCCTAGCGTGGATT
TGCTGTGCTACAGATTTCTGGATCAATTTATCTCAGCTCACGAGATCTCC
TCTCATTCTTTTACACAAATGCTTTCAGTTCTCATTGGAATCCTTCAATG
CCAATCATCTATCCGCACCAAAAAGTTCTGCATTCTCCTCGAGCTCGTCG
GCAGCATTCTCCATCGGTGGATTCCTTCAGATTCCTCCACATCGAATCAG
CAAGTCTGCGAATATCTGGAGAGTTATTTGCAACTGATCTCAGCGAATTC
CAAATATGAAACCGATGTGGAAATCCGAATCTCTTGTGCTGAATCGCTGA
GGAGATGCCTGCAGAATGCCGATTGGAGGGATTATTACCATGGCAACAAC
ACATTCATTGAGATCGCAATCACCCAGCTGAGCGATGAGAATGACCATAT
CAGGAATCTCGCTGCTTTGTCTGTTGCGATCGTCCTCCAAATGCCCTCGC
TGCGATCGATTGTTCCCTCCGCTGTCCTCAGCAAGTATTTCAAATTGATT
ATTTGCGGGAGCCAATCAAATTCTGTTCGCATTCTATCCGATCTTTCTCC
GATTGGATATCAAATAGGAAATGTTAAATATTCACAGGGAAAGATTTCAG
TTTTCGATTCAGAAGAAATCAATTTCTACTATGATTTCTACGATGTCCAT
TCTGATTTGAAATTGGATCTGAATCAAGGCAACGAGTTTCTATACCGATC
CAGTTTCCAGGAGATTTTGCTGGGAACCAGCAAATTCTCATCTGCTTATC
AAAATAAGCTATTGAATCGATAAATTGTTTCTTGAAATAAAATTGGTCTT
CTATTGATTTTTATATAAATTTTAATTTTTAGATGCTCCGGTGGACTTGA
TGATTTCCGGCAATCTCTAATCGGGGGAAAAGAGTTGGAAATTATAGTTG
ATTATCAGAAGCTATTATCTAATTTTATCTCACTATATTTCGGTACATCT
CATTTGATGACTTTTATTGTACGGTAATATTGGATAGTGTGCAAGAAAGT
TGATAGGAAAGGAGCTGTTTTATATGCATGAAATGTAAAAATTATTTAGT
GTTGTAGAGTAGATTACGCTGA
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protein sequence of SMED30023155-orf-1

>SMED30023155-orf-1 ID=SMED30023155-orf-1|Name=SMED30023155-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1066bp
MEMFAILCKEISRQNQRNYQLWNQILRFLISNLSIASNKLRQHFVNCFRQ
LVNGIIRQNIDSSQAVSTEFLAKLLRYLSRNLYPIASFYKRSSFLAVLNL
IFNSFDSGIIFDLLDMSDAEYVIFLKTLVYFFADTFEENRMNASKCFIIL
VNTKPLVDHYESLKQIALEKSNTSNPHDCAVAFTIMKTLLGIEEYKLLPH
VIADQLIARLECSLESIKSNIELFHIAMNSPFYSSLYCLRYLLDEHFENI
SSQLSVTRIISLCYAINDVIFPFNSSAAPEGCLPDEVRNLLDSHFVESHP
EYLTICCWRSCKEISLILGNIAAELVNKSSDNFNQVQQIADFFFDQITSV
THKGAFESLCGGFEKLCQSLWRSSTMEIVEIPMSFIRKSIDIIHTNEDLC
STRRSAGLPHLFLVLITSEPLVNKQRSSLNFAMDQLNSILVKADSQNSAD
QKRIIHIFNISRLLFKESSLLTQLINHTFSAVKYSVQFFSSNIWPLRNSA
TLLYCALIERIFGPSKTIKFHNKFNRLNSKVFFNRYQNMYEFIVNTIKEC
DKSPLNLNSSTRIYPILVILGRLVPELDHFNSSSYDLTYLKHKIQRYLSS
SVWVIRVSAAKAIAALALGESVLSIDTIRDLTQQIIDCPRNHNLIHGSIK
AIRCIFEDLLDNLFISDNQWALLRGISAEIWNRLSPVILSLRTDSRCPQE
FIDLIEFIHGKSSKFLEQINFNSYLTEITSLWQVKLLFIALESNRIDEDM
KYVKGISIGALQNAEYKIRKEMLIKLSLNPEIINKIFPRFDIDLIFHLAC
SESHPSVDLLCYRFLDQFISAHEISSHSFTQMLSVLIGILQCQSSIRTKK
FCILLELVGSILHRWIPSDSSTSNQQVCEYLESYLQLISANSKYETDVEI
RISCAESLRRCLQNADWRDYYHGNNTFIEIAITQLSDENDHIRNLAALSV
AIVLQMPSLRSIVPSAVLSKYFKLIICGSQSNSVRILSDLSPIGYQIGNV
KYSQGKISVFDSEEINFYYDFYDVHSDLKLDLNQGNEFLYRSSFQEILLG
TSKFSSAYQNKLLNR*
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protein sequence of SMED30023155-orf-2

>SMED30023155-orf-2 ID=SMED30023155-orf-2|Name=SMED30023155-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=275bp
LYLAILSSFSFLNLIENNYLINLIEFINRKSPRNYDESILKSMFFRKLCD
IISINKEHEKTMEISEYLIDHAFDQQFIKQTSIRNNTTSVLSSGLSIHLN
KCQKCSRTVLCRELFQRLLKLFQQSWNVSGKFSFINIFIRVFSGEVIRKI
EPKIELILLQTAQEYSLSTYACDSYISLLTASNNSSIGIELIVEIFHREN
PETSFSNIDSIRKTICEYFVPKLTQENCGKLTEIVFYALKCYGKSRFPME
FSGDRSSLKKKSIRLRGKGFWVRC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0002056medial muscle cell
PLANA:0002109X1 cell
PLANA:0002111X2 cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR019442DUF2428_death-receptor-like
IPR016024ARM-type_fold
Vocabulary: molecular function
TermDefinition
GO:0005488binding
GO:0005515protein binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019442Domain of unknown function DUF2428, death-receptor-likePFAMPF10350DUF2428coord: 256..494
e-value: 4.8E-50
score: 170.4
NoneNo IPR availablePANTHERPTHR14387THADA/DEATH RECEPTOR INTERACTING PROTEINcoord: 25..1020
IPR016024Armadillo-type foldSUPERFAMILYSSF48371ARM repeatcoord: 793..958
IPR016024Armadillo-type foldSUPERFAMILYSSF48371ARM repeatcoord: 234..976