HIV Tat-specific factor 1

Overview


Name	HIV Tat-specific factor 1
Smed ID	SMED30023117
Length (bp)	1464

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of HIV Tat-specific factor 1 (SMED30023117) t-SNE clustered cells

Violin plots show distribution of expression levels for HIV Tat-specific factor 1 (SMED30023117) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of HIV Tat-specific factor 1 (SMED30023117) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for HIV Tat-specific factor 1 (SMED30023117) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30023117

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30023117	SMESG000021348.1	SmedASXL_006598	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
muscle cell	SMED30023117	SMESG000021348.1	dd_Smed_v4_4508_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Human
Match: HTATSF1 (HIV-1 Tat specific factor 1 [Source:HGNC Symbol;Acc:HGNC:5276])

HSP 1 Score: 176.407 bits (446), Expect = 2.084e-47
Identity = 106/300 (35.33%), Postives = 173/300 (57.67%), Query Frame = 1

Query:  274 WFLRLTKDFLDICQL------ENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKT--IRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            WF ++T+DF+   Q       +    +T  +ED + +  +   +  EK  +     KK   + AES WF ++E++N N+Y+  LP DI  +EF++L+SK+G++M +P T   KVKLYK+  G  KGDG CCYLK ES+ LAL LLD   +RG  L V  AKF+ K  +D  K++K     KKKL  +Q+ L  W PE +    R + +  VI+KN+F P   +++P +  +I++ +  E    G ++ +++ D HP+ V  ++F+D   +D  ++  + + +  R I+A+ WDG T Y+V
Sbjct:   59 WFPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQ--EKAPEPTDARKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSMQQKQL-DWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQV 355

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Query:  274 WFLRLTKDFLDICQL------ENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKT--IRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            WF ++T+DF+   Q       +    +T  +ED + +  +   +  EK  +     KK   + AES WF ++E++N N+Y+  LP DI  +EF++L+SK+G++M +P T   KVKLYK+  G  KGDG CCYLK ES+ LAL LLD   +RG  L V  AKF+ K  +D  K++K     KKKL  +Q+ L  W PE +    R + +  VI+KN+F P   +++P +  +I++ +  E    G ++ +++ D HP+ V  ++F+D   +D  ++  + + +  R I+A+ WDG T Y+V
Sbjct:   59 WFPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQ--EKAPEPTDARKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSMQQKQL-DWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQV 355

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Human
Match: HTATSF1 (HIV-1 Tat specific factor 1 [Source:HGNC Symbol;Acc:HGNC:5276])

HSP 1 Score: 114.39 bits (285), Expect = 2.187e-28
Identity = 68/169 (40.24%), Postives = 99/169 (58.58%), Query Frame = 1

Query:  274 WFLRLTKDFLDICQL------ENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFD 762
            WF ++T+DF+   Q       +    +T  +ED + +  +      EK  +     KK   + AES WF ++E++N N+Y+  LP DI  +EF++L+SK+G++M +P T   KVKLYK+  G  KGDG CCYLK ES+ LAL LLD   +RG  L V  AKF+ K  +D
Sbjct:   59 WFPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAE--EPPQEKAPEPTDARKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYD 225

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Human
Match: HTATSF1 (HIV-1 Tat specific factor 1 [Source:HGNC Symbol;Acc:HGNC:5276])

HSP 1 Score: 112.849 bits (281), Expect = 4.253e-28
Identity = 67/165 (40.61%), Postives = 97/165 (58.79%), Query Frame = 1

Query:  274 WFLRLTKDFLDICQL------ENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKK 750
            WF ++T+DF+   Q       +    +T  +ED + +  +      EK  +     KK   + AES WF ++E++N N+Y+  LP DI  +EF++L+SK+G++M +P T   KVKLYK+  G  KGDG CCYLK ES+ LAL LLD   +RG  L V  AKF+ K
Sbjct:   59 WFPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAE--EPPQEKAPEPTDARKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLK 221

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Celegans
Match: cus-2 (pep chromosome:WBcel235:I:654090:658810:1 gene:WBGene00022025.1 transcript:Y65B4A.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:cus-2)

HSP 1 Score: 188.348 bits (477), Expect = 3.843e-54
Identity = 97/237 (40.93%), Postives = 154/237 (64.98%), Query Frame = 1

Query:  445 AESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQES-LFRWGPET-KTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            A+  W ++  +K   +Y+ NLP DI + EF + +SK G++  +  TN PK KLY+  +G  KGDG+CCY+K ES+ LA N+LDG NL G  +KV  A+FE K  FDP ++R+     +KK   +Q++ +F W P+  +  RPK D TVI+KN+F   +M +N  L +D+K+++++  +  G VK ++V+  HP+ VV + F     SD+AV+Y + ++ + R ++AE+WDGRTK+KV
Sbjct:  167 AKEGWLDLG-DKVHAVYVSNLPEDITDEEFQKFMSKCGVIQPDIRTNKPKCKLYREENGKLKGDGRCCYIKKESVELACNILDGANLNGREVKVEEARFEMKGDFDPARKRRKLTAAQKKRYMEQQNKIFEWTPDKPRNYRPKSDCTVIVKNLFTQEMMNKNAALMLDLKEEMTQSCQKYGIVKKVVVYANHPDGVVSVTFPTTEESDMAVKYLHGRVVDGRKLTAELWDGRTKFKV 402

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Fly
Match: barc (gene:FBgn0037081 transcript:FBtr0078399)

HSP 1 Score: 191.815 bits (486), Expect = 2.226e-54
Identity = 97/242 (40.08%), Postives = 155/242 (64.05%), Query Frame = 1

Query:  457 WFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPET-KTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETEDEEKVR 1179
            WFE+D  +N  +Y+ NLPLDI  +EF +L+ K G++M +P T   K+KLY   DG  KGDG C Y+K+ES+NLAL +LD YNLRG  ++V RA+F+ +  ++P  + K   K+K+KL K +E LF W P+  +  R K + TVI+KN+F P + ++  +L ++ ++ + +E    G V+ ++++D HP+ V QIN      +D+ ++    + +  R +SAE WDG+TKYK++E+  E   R
Sbjct:  275 WFEMDPLQNTKVYVSNLPLDITMDEFADLMGKCGMVMRDPQTQKFKLKLYAEKDGQIKGDGLCDYIKVESVNLALKILDEYNLRGHKIRVQRAQFQMRGEYNPALKPKRKKKDKEKLQKMKEKLFDWRPDKLRGERSKNEKTVIIKNLFTPELFEKEVELILEYQNNLREECSKCGMVRKVVIYDRHPDGVAQINMASPEEADLVIQMMQGRYFGQRQLSAEAWDGKTKYKIEESAVEAHER 516

HSP 2 Score: 53.5286 bits (127), Expect = 3.316e-7
Identity = 20/38 (52.63%), Postives = 28/38 (73.68%), Query Frame = 1

Query:  109 TRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFL 222
            T  D+DG+E  WD  K AWFP IDD+F+ ++ +NYGF+
Sbjct:  178 TYTDKDGVEFFWDATKSAWFPKIDDDFMARYQMNYGFI 215

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Fly
Match: barc (gene:FBgn0037081 transcript:FBtr0078400)

HSP 1 Score: 191.815 bits (486), Expect = 2.226e-54
Identity = 97/242 (40.08%), Postives = 155/242 (64.05%), Query Frame = 1

Query:  457 WFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPET-KTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETEDEEKVR 1179
            WFE+D  +N  +Y+ NLPLDI  +EF +L+ K G++M +P T   K+KLY   DG  KGDG C Y+K+ES+NLAL +LD YNLRG  ++V RA+F+ +  ++P  + K   K+K+KL K +E LF W P+  +  R K + TVI+KN+F P + ++  +L ++ ++ + +E    G V+ ++++D HP+ V QIN      +D+ ++    + +  R +SAE WDG+TKYK++E+  E   R
Sbjct:  275 WFEMDPLQNTKVYVSNLPLDITMDEFADLMGKCGMVMRDPQTQKFKLKLYAEKDGQIKGDGLCDYIKVESVNLALKILDEYNLRGHKIRVQRAQFQMRGEYNPALKPKRKKKDKEKLQKMKEKLFDWRPDKLRGERSKNEKTVIIKNLFTPELFEKEVELILEYQNNLREECSKCGMVRKVVIYDRHPDGVAQINMASPEEADLVIQMMQGRYFGQRQLSAEAWDGKTKYKIEESAVEAHER 516

HSP 2 Score: 53.5286 bits (127), Expect = 3.316e-7
Identity = 20/38 (52.63%), Postives = 28/38 (73.68%), Query Frame = 1

Query:  109 TRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFL 222
            T  D+DG+E  WD  K AWFP IDD+F+ ++ +NYGF+
Sbjct:  178 TYTDKDGVEFFWDATKSAWFPKIDDDFMARYQMNYGFI 215

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Zebrafish
Match: htatsf1 (HIV-1 Tat specific factor 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1578])

HSP 1 Score: 196.823 bits (499), Expect = 5.389e-57
Identity = 133/359 (37.05%), Postives = 195/359 (54.32%), Query Frame = 1

Query:   79 QEINNKIHPTTRID-EDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPE-TKTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            Q   N   P T  D EDG    WD EK+AWFP I+D+FI  +  NYGF   EE   +   AV   E     ++      + +  +  T P E             A +  KNK   KK   + A+ TWFE+++ KN N+Y+  LP DI  +EFVE++SK G++M +P T   K+K+YK+ DG  KGDG CCYLK ES+ LA  LLD   +RG  L V  A+FE K  FD   ++K  NKE +K L++Q+    W PE +  +R + +  +I++N+F P   +E+P +  + +D +  E +  G VK +I+ D HP+ V  + FK+   +D      N + +  R +SA +WDG T Y+V
Sbjct:   23 QRQENSDDPYTYTDPEDGTVYDWDHEKRAWFPKINDDFIAAYQANYGF--NEEGAPDPSAAVNSAESLPAKSE------EPKKPEEPTKPAE-------------APEQGKNKEGEKKGEKRKADPTWFEVEKEKNTNVYVTGLPPDITPDEFVEVMSKCGIVMRDPITEEYKIKIYKDKDGNQKGDGLCCYLKKESVALAKQLLDETEIRGYRLHVEEARFELKGQFD-ASKKKKKNKEYRKKLQQQQKQLDWRPEKSGEVRKRHEKVIIIQNMFHPTDFEEDPLVLNEYRDDLRTECEKFGQVKKVIIFDRHPDGVASVAFKEPEEADACQVALNGRWFGGRKLSALLWDGVTDYQV 359

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Mouse
Match: Htatsf1 (HIV TAT specific factor 1 [Source:MGI Symbol;Acc:MGI:1919709])

HSP 1 Score: 186.037 bits (471), Expect = 5.542e-51
Identity = 122/367 (33.24%), Postives = 195/367 (53.13%), Query Frame = 1

Query:   55 DTMNDDICQEINNKIHPTTRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKTI--RPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            D    D   E + + H   +  +D    +WD +K+AWFP I ++FI  +  NYGF S   + + + TA VQ                    D  T  +E+   K          +  +     +K   + AES WF ++E++N N+Y+  LP DI  +EF++L+SK+G++M +P T   KVKLYK+  G  KGDG CCYLK ES+ LAL LLD   +RG  L V  AKF+ K  +D  K++K     KKKL  +Q+ L  W PE +    R + +  VILKN+F P   +++P +  +I++ +  E    G ++ +++ D HP+ V  ++F++   +D  ++  + + +  R I+A+ WDG T Y+V
Sbjct:   25 DPKEGDTQNEPSGEAHSLGQPPDD-TPYEWDLDKKAWFPKITEDFIATYQANYGFSS---DGASSSTANVQ--------------------DANTKAVEEPPQK----------EVPETPDSKRKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDDQGNLKGDGLCCYLKKESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSLQQKQL-DWRPERRAGPNRLRHERVVILKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFREPEEADHCIQTLDGRWFGGRQITAQAWDGTTDYQV 356

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Mouse
Match: Htatsf1 (HIV TAT specific factor 1 [Source:MGI Symbol;Acc:MGI:1919709])

HSP 1 Score: 103.99 bits (258), Expect = 2.618e-25
Identity = 68/205 (33.17%), Postives = 104/205 (50.73%), Query Frame = 1

Query:   55 DTMNDDICQEINNKIHPTTRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESI 669
            D    D   E + + H   +  +D    +WD +K+AWFP I ++FI  +  NYGF S   + + + TA VQ                    D  T  +E+   K          +  +     +K   + AES WF ++E++N N+Y+  LP DI  +EF++L+SK+G++M +P T   KVKLYK+  G  KGDG CCYLK+ S+
Sbjct:   25 DPKEGDTQNEPSGEAHSLGQPPDD-TPYEWDLDKKAWFPKITEDFIATYQANYGFSS---DGASSSTANVQ--------------------DANTKAVEEPPQK----------EVPETPDSKRKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDDQGNLKGDGLCCYLKVFSV 195

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BLAST of HIV Tat-specific factor 1 vs. UniProt/SwissProt
Match: sp|Q8BGC0|HTSF1_MOUSE (HIV Tat-specific factor 1 homolog OS=Mus musculus OX=10090 GN=Htatsf1 PE=1 SV=1)

HSP 1 Score: 186.037 bits (471), Expect = 3.877e-50
Identity = 122/367 (33.24%), Postives = 195/367 (53.13%), Query Frame = 1

Query:   55 DTMNDDICQEINNKIHPTTRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKTI--RPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            D    D   E + + H   +  +D    +WD +K+AWFP I ++FI  +  NYGF S   + + + TA VQ                    D  T  +E+   K          +  +     +K   + AES WF ++E++N N+Y+  LP DI  +EF++L+SK+G++M +P T   KVKLYK+  G  KGDG CCYLK ES+ LAL LLD   +RG  L V  AKF+ K  +D  K++K     KKKL  +Q+ L  W PE +    R + +  VILKN+F P   +++P +  +I++ +  E    G ++ +++ D HP+ V  ++F++   +D  ++  + + +  R I+A+ WDG T Y+V
Sbjct:   25 DPKEGDTQNEPSGEAHSLGQPPDD-TPYEWDLDKKAWFPKITEDFIATYQANYGFSS---DGASSSTANVQ--------------------DANTKAVEEPPQK----------EVPETPDSKRKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDDQGNLKGDGLCCYLKKESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSLQQKQL-DWRPERRAGPNRLRHERVVILKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFREPEEADHCIQTLDGRWFGGRQITAQAWDGTTDYQV 356

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BLAST of HIV Tat-specific factor 1 vs. UniProt/SwissProt
Match: sp|O43719|HTSF1_HUMAN (HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1)

HSP 1 Score: 176.407 bits (446), Expect = 1.001e-46
Identity = 106/300 (35.33%), Postives = 173/300 (57.67%), Query Frame = 1

Query:  274 WFLRLTKDFLDICQL------ENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKT--IRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            WF ++T+DF+   Q       +    +T  +ED + +  +   +  EK  +     KK   + AES WF ++E++N N+Y+  LP DI  +EF++L+SK+G++M +P T   KVKLYK+  G  KGDG CCYLK ES+ LAL LLD   +RG  L V  AKF+ K  +D  K++K     KKKL  +Q+ L  W PE +    R + +  VI+KN+F P   +++P +  +I++ +  E    G ++ +++ D HP+ V  ++F+D   +D  ++  + + +  R I+A+ WDG T Y+V
Sbjct:   59 WFPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQ--EKAPEPTDARKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSMQQKQL-DWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQV 355

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BLAST of HIV Tat-specific factor 1 vs. UniProt/SwissProt
Match: sp|Q5RB63|HTSF1_PONAB (HIV Tat-specific factor 1 homolog OS=Pongo abelii OX=9601 GN=HTATSF1 PE=2 SV=1)

HSP 1 Score: 176.022 bits (445), Expect = 1.635e-46
Identity = 106/300 (35.33%), Postives = 173/300 (57.67%), Query Frame = 1

Query:  274 WFLRLTKDFLDICQL------ENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKT--IRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            WF ++T+DF+   Q       +    +T  +ED + +  +   +  EK  +     KK   + AES WF ++E++N N+Y+  LP DI  +EF++L+SK+G++M +P T   KVKLYK+  G  KGDG CCYLK ES+ LAL LLD   +RG  L V  AKF+ K  +D  K++K     KKKL  +Q+ L  W PE +    R + +  VI+KN+F P   +++P +  +I++ +  E    G ++ +++ D HP+ V  ++F+D   +D  ++  + + +  R I+A+ WDG T Y+V
Sbjct:   59 WFPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQ--EKAPEPTDPRKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKKLSMQQKQL-DWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQV 355

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BLAST of HIV Tat-specific factor 1 vs. UniProt/SwissProt
Match: sp|O43120|UAP2_SCHPO (Splicing factor U2AF-associated protein 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=uap2 PE=1 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 4.790e-23
Identity = 64/246 (26.02%), Postives = 128/246 (52.03%), Query Frame = 1

Query:  481 NKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLR---GCILKVSRAK--FEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKTIRPKK----DNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYK------VKETEDEEK 1173
            NK +YI+ LPLD+  +E  E+  K G++        P++K+Y+  DGT KGD    + + ES+ LA  L D    R   G  ++V +A   ++K++  +      +  K  +   ++ + +  W    + +  K+    +  V+LK++F    + + P+L +D+KD I++E +  G V +++++D  P+ VV + F +   ++  V     + ++ R + A I+DG+ +++      + + EDEEK
Sbjct:  109 NKAVYIQGLPLDVTVDEIEEVFKKCGVIAKNIDNGTPRIKIYRTEDGTPKGDALIVFFRSESVELAEQLFDDTEFRYGSGQKMRVQKANIDYKKEKTVNKDVGGALKKKALRLRQQQMQQISSWDDVDEEVDDKRKKRFNKIVVLKHIFTLEELDKTPELLIDLKDDITEEAEKCGRVTNVVLYDKEPDGVVTVRFSNNEEAEACVRLMQGRYFDGRVVEASIYDGKVRFQKSGKHTLDDEEDEEK 354

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BLAST of HIV Tat-specific factor 1 vs. UniProt/SwissProt
Match: sp|P53830|CUS2_YEAST (Cold sensitive U2 snRNA suppressor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CUS2 PE=1 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 4.497e-8
Identity = 64/208 (30.77%), Postives = 87/208 (41.83%), Query Frame = 1

Query:  475 NKNKNIYIENLPLDIEENE-FVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRW-GPETKTIRPKK---------------------DNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVV 1029
            +KN +IYI  LP D    E   E   KYG++        P  KLY N  G  KGD    Y K ES+ LA+ +++     G  ++V RA+F+ KEG                +  K+  L  + GPE    R KK                     D TVI  NVF+      N D+  DI++ + +  + IG V SI V     EA V
Sbjct:   42 SKNTSIYISGLPTDKTTKEGLTEQFCKYGMIRTNR-DGEPLCKLYVNDKGAFKGDALITYSKEESVTLAIEMMNESIFLGKQIRVERAQFQNKEG--------------DNMHGKENDLKEFNGPEPPIKRLKKAKSEGEGEVIDYNDDESLAKADRTVIFANVFNIYKSYTNDDIN-DIQEDLLEGCEEIGQVDSISVSPNKGEATV 233

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BLAST of HIV Tat-specific factor 1 vs. TrEMBL
Match: A0A087UHQ3 (HIV Tat-specific factor 1 (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_23879 PE=4 SV=1)

HSP 1 Score: 223.787 bits (569), Expect = 4.270e-64
Identity = 135/362 (37.29%), Postives = 203/362 (56.08%), Query Frame = 1

Query:  103 PTTRIDE-DGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPX-XXXXXXXXXXXXXXXXQESLFRWGPET-KTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETEDEEKVR 1179
            P T +D  DG   +W+ EKQAWFP +DD+FI K+  NY + S E ++S+  +   QP+   R   D                                                     WF++DE+ N N+Y+  LP D  E EF+EL+SK GL+M +P     K+KLY++ DGT KGDG+CCY+KIES+ LAL++LDGY  +G  + V RA+FE K  +DP  K +K   KEK+KL KK + LF W P+  + +R + +NTVI+KN+FDP    E+  L +D ++ I +E    G VK ++++D +P+ VV + F +  ++D  +   N + + +R ++AE WDG+TKYK+ ETE+E + R
Sbjct:   30 PYTYVDPNDGTVYEWNTEKQAWFPKVDDDFIAKYQSNYTYQSNE-DESKGTSPEPQPKGEKRKAND---------------------------------------------------PGWFQVDEDHNTNVYVSGLPQDTTEEEFIELMSKCGLIMKDPDNMKYKIKLYRDSDGTLKGDGRCCYIKIESVKLALDILDGYLFKGKPIHVERAQFELKGQYDPSKKPKKKKAKEKEKLKKKLDKLFDWRPDKLRGMRSRNENTVIIKNMFDPKEFDEDAALLLDYQNDIREECSKCGEVKKVVIYDRNPDGVVAVTFSEPEMADECINLMNGRWFASRQLTAETWDGKTKYKIVETEEEREKR 339

[Close]

BLAST of HIV Tat-specific factor 1 vs. TrEMBL
Match: A0A1Y1KY94 (RRM domain-containing protein OS=Photinus pyralis OX=7054 GN=PPYR_12769 PE=4 SV=1)

HSP 1 Score: 219.935 bits (559), Expect = 1.829e-62
Identity = 133/356 (37.36%), Postives = 198/356 (55.62%), Query Frame = 1

Query:  109 TRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTN-KGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXX-XXQESLFRWGPE-TKTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETEDE 1167
            T  D DG++  WD +K AWFP +DDEF+  + LNYGF+  E+   + +  +                                        ++  EK  +   +  KR   P E TWF++D+  N N+Y+ NLPL + E+EFVE + K GL+M +  T   KVKLY +P+  + KGD  C Y++IES+NLAL LLDG +L+G  +K+ RAKF+ K  FDPK + K   K++++ L + QE LF W PE  +  R K +  VIL NVF P++   +  L ++I+  + +E    G VK +I++D HPE V Q+N K+   +D  V+  N + +  R + AEIWDGRTKYK+ ET+ +
Sbjct:   98 TYTDSDGVKYFWDTQKNAWFPKLDDEFMAMYQLNYGFVQNEQAPPKADEVI----------------------------------------TKEVEKKPEKVEQAPKRKAPPPEPTWFDVDDEHNTNVYVTNLPLSLTEDEFVEFMQKCGLVMRDLSTGKMKVKLYIDPETKSFKGDALCTYIRIESVNLALQLLDGSDLKGNKVKLERAKFQMKGAFDPKLKPKKRKKKEREKLKRMQEKLFDWRPEKMRGERAKHEKVVILTNVFVPSMFDADVSLILEIQQDLREECSKCGTVKKVIMYDQHPEGVAQVNMKEPEEADAVVQLLNGRWFGKRKLFAEIWDGRTKYKIAETDSQ 413

[Close]

BLAST of HIV Tat-specific factor 1 vs. TrEMBL
Match: A0A1S3KG96 (HIV Tat-specific factor 1 homolog isoform X1 OS=Lingula unguis OX=7574 GN=LOC106181608 PE=4 SV=1)

HSP 1 Score: 222.246 bits (565), Expect = 3.927e-62
Identity = 110/243 (45.27%), Postives = 165/243 (67.90%), Query Frame = 1

Query:  454 TWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETK-TIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETEDEEKVR 1179
            TWFE+D+N+N N+Y+  LP ++EE EF EL+SK G++MY+  T  PK+KLY+N DGT KGDG+CCY+K+ES++LAL +LDG + +   + V RA+F+ K  +DP K++K++NK K+K+ +KQE +F W P+     R K +  V++K++FDP   + +P L  DI+D I  E    G V+ +IV+D +PE V  + F     +D+ VE FN + +  R + AE WDG+TKY+VKET  E + R
Sbjct:  263 TWFEVDQNRNTNVYVSGLPANMEETEFQELMSKCGMIMYDHITRKPKIKLYRNEDGTLKGDGRCCYIKVESVDLALKILDGSSYKDHTIHVERAQFQLKGDYDPSKKKKVSNKMKRKIKEKQEKMFDWRPDKPLGTRGKHEKVVVIKHMFDPKEFETDPSLINDIRDDIRTEASKYGEVRKVIVYDRNPEGVATVAFHAPEHADLCVEAFNGRWFAKRQLVAETWDGKTKYEVKETAAEREAR 505

[Close]

BLAST of HIV Tat-specific factor 1 vs. TrEMBL
Match: Q7Q5Q6 (AGAP006266-PA OS=Anopheles gambiae OX=7165 GN=1276920 PE=4 SV=4)

HSP 1 Score: 224.172 bits (570), Expect = 4.036e-62
Identity = 137/367 (37.33%), Postives = 208/367 (56.68%), Query Frame = 1

Query:   64 NDDICQEINNKIHPTTRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGP-ETKTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETE 1161
             DD      + +H  T  D+DG    WDEE++AWFP +DDEF+  + LNYGF+   +N S             R+      + +    +L   P  D ++   +   E          K KKR   P    WFEI    N  +Y+ NLP DI E EF EL+SK G++M +P T+  K+KLY+ PDGT KGDG C Y+KIES++LAL +LD Y++RG  +KV RA+F+ +  ++P  + K+  KEK++L K QESLF W P + +  R K +  VI+KN+F+P +      L ++ ++ + +E    G V+ ++++D HPE V Q+   D   +D+ V+  N + +  R ++A IWDGRTKY++ ET+
Sbjct:  208 GDDRSYGYEDGVH--TYKDKDGAVYFWDEERKAWFPKVDDEFMAIYQLNYGFI---DNTSSGGGPAAAAPAPARV------VSEPSGREL---PGCDEDDDADEQGEEAQRALAAAAAKGKKRKAPPEPPKWFEIAPEHNTKVYVSNLPTDISEEEFGELMSKCGMVMKDPKTHKLKLKLYREPDGTLKGDGLCHYIKIESVDLALKILDNYDVRGHKIKVQRAEFQMRGEYNPTLKPKMRKKEKERLKKIQESLFDWRPVKMRGERSKHERIVIIKNLFEPELFDREVHLLLEYQNDLREECGKCGTVRRVLLYDRHPEGVAQVTMGDPEEADLVVQLMNGRFFGQRKLTAAIWDGRTKYRIAETD 560

[Close]

BLAST of HIV Tat-specific factor 1 vs. TrEMBL
Match: A0A1S3KFU8 (HIV Tat-specific factor 1 homolog isoform X2 OS=Lingula unguis OX=7574 GN=LOC106181608 PE=4 SV=1)

HSP 1 Score: 221.476 bits (563), Expect = 4.069e-62
Identity = 110/243 (45.27%), Postives = 165/243 (67.90%), Query Frame = 1

Query:  454 TWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETK-TIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETEDEEKVR 1179
            TWFE+D+N+N N+Y+  LP ++EE EF EL+SK G++MY+  T  PK+KLY+N DGT KGDG+CCY+K+ES++LAL +LDG + +   + V RA+F+ K  +DP K++K++NK K+K+ +KQE +F W P+     R K +  V++K++FDP   + +P L  DI+D I  E    G V+ +IV+D +PE V  + F     +D+ VE FN + +  R + AE WDG+TKY+VKET  E + R
Sbjct:  263 TWFEVDQNRNTNVYVSGLPANMEETEFQELMSKCGMIMYDHITRKPKIKLYRNEDGTLKGDGRCCYIKVESVDLALKILDGSSYKDHTIHVERAQFQLKGDYDPSKKKKVSNKMKRKIKEKQEKMFDWRPDKPLGTRGKHEKVVVIKHMFDPKEFETDPSLINDIRDDIRTEASKYGEVRKVIVYDRNPEGVATVAFHAPEHADLCVEAFNGRWFAKRQLVAETWDGKTKYEVKETAAEREAR 505

[Close]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Cavefish
Match: htatsf1 (HIV-1 Tat specific factor 1 [Source:NCBI gene;Acc:103032098])

HSP 1 Score: 191.43 bits (485), Expect = 5.656e-55
Identity = 124/351 (35.33%), Postives = 194/351 (55.27%), Query Frame = 1

Query:  103 PTTRID-EDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPE-TKTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            P T +D EDG    WD +K+AWFP I ++FI  +  NYGF   E+   ++E A    E     ++   ++ + E         +  + K  +  S         K   +K   + AE  WF+I+++KN N+Y+  LP DI  +EFVE++SK G++M +P T   KVKLYK+ DG  KGDG CCYLK ES+ LA  LLD   +RG  L V  A+FE K  +D  K++K + + +KK+  +Q+ L  W PE T   R + +  VI++N+F P   +E+P    + ++ +  E +  G VK +I+ D HP+ V  + FK+   +D+     + + +  R +SA++WDG T Y+V
Sbjct:   31 PFTYVDPEDGTVYDWDHDKKAWFPKITEDFIAAYQANYGF--SEDGTPDSEAAGPPSE----TSEKPEEMEKPEEEKKKNEVKKPEDGKQPEISS--------TKEGKQKGEKRKAEPGWFDIEKDKNTNVYVSGLPPDITPDEFVEVMSKCGIIMRDPITEEYKVKLYKDSDGNQKGDGLCCYLKKESVALAERLLDEMEIRGYRLHVEAARFELKGQYDASKKKKKSKEYRKKMQLQQKQL-DWRPEKTADGRKRHERVVIIQNMFHPKDFEEDPLELNEYREDLRSECEKFGEVKKVIIFDRHPDGVASVAFKEPEEADMCQTVLDGRWFGGRKLSAQLWDGVTDYQV 366

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Yeast
Match: CUS2 (Putative checkpoint factor in transcription; binds to U2 snRNA and Prp11p; regulates toggling of the U2 snRNA stem II region between different structures; contains two RNA recognition motifs (RRMs) [Source:SGD;Acc:S000005230])

HSP 1 Score: 58.151 bits (139), Expect = 6.476e-10
Identity = 64/208 (30.77%), Postives = 87/208 (41.83%), Query Frame = 1

Query:  475 NKNKNIYIENLPLDIEENE-FVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRW-GPETKTIRPKK---------------------DNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVV 1029
            +KN +IYI  LP D    E   E   KYG++        P  KLY N  G  KGD    Y K ES+ LA+ +++     G  ++V RA+F+ KEG                +  K+  L  + GPE    R KK                     D TVI  NVF+      N D+  DI++ + +  + IG V SI V     EA V
Sbjct:   42 SKNTSIYISGLPTDKTTKEGLTEQFCKYGMIRTNR-DGEPLCKLYVNDKGAFKGDALITYSKEESVTLAIEMMNESIFLGKQIRVERAQFQNKEG--------------DNMHGKENDLKEFNGPEPPIKRLKKAKSEGEGEVIDYNDDESLAKADRTVIFANVFNIYKSYTNDDIN-DIQEDLLEGCEEIGQVDSISVSPNKGEATV 233

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BLAST of HIV Tat-specific factor 1 vs. Ensembl Nematostella
Match: EDO33511 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRZ1])

HSP 1 Score: 147.517 bits (371), Expect = 1.779e-40
Identity = 82/241 (34.02%), Postives = 141/241 (58.51%), Query Frame = 1

Query:  457 WFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETEDEEKVR 1179
            WF+ D  KN N+Y+  LPLDI + EFVEL+SKYG++M +P T+                 G+CCYLK+ S++LA++LLD    +   L V +A+F  K  ++P  ++K   K+KK+  + QE L  W  +    RPK +  +++KN+FDP + +++P L +  ++ + KE +  G V+ +IV D H E +  + FK+   +D  +E  N + +  R ++A+ WDG + + ++E++ + K R
Sbjct:   63 WFQPDPEKNPNVYVSGLPLDITDEEFVELMSKYGIIMEDPDTH-----------------GRCCYLKMASVHLAIDLLDEAEYKKSTLHVEQAQFNMKGNYNPALKKKKKKKKKKQGKQ-QEKLLDW-VDRDNRRPKNERVIVIKNMFDPKVFEKDPQLIITTRNDLRKECEKFGDVRKVIVFDRHSEGICSVAFKEHPPADACLERMNGRWFAGRRLAADRWDGVSNFNIQESDKDLKDR 284

[Close]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Medaka
Match: htatsf1 (HIV Tat-specific factor 1 [Source:NCBI gene;Acc:101155132])

HSP 1 Score: 201.06 bits (510), Expect = 9.791e-59
Identity = 134/373 (35.92%), Postives = 197/373 (52.82%), Query Frame = 1

Query:   61 MNDDICQEINNKIHPTTRID-EDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWY-KFYSENA-------EXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKT-IRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            M++   Q  ++   P T  D  DG    WD EK+AWFP + D+FI  +  NYGF +KE +   N  AV                        +  P  + N+K   K  SE +       +         +K   + A+  WFEIDE KN N+Y+  LP DI   EFV L+SKYG++M +P T   KVKLYK+ DG  KGDG CCYLK ES+ LA+ LLD Y +RG  L V  A+FE K G     ++K  +K+ KK L++Q+    W PE K  +R + +  VI++N+F P+  +E+P +  + ++ +  E +  G VK +++ D HP+ V  + FK+   +D  V  FN + +  R + A +WDG T Y+V
Sbjct:   17 MHELYGQRKDDGSDPFTYTDPADGTVYDWDPEKKAWFPKVTDDFIAAYQANYGF-TKEGDPDTNAGAVSS----------------------SDPPAPEPNSKAPEKAKSETSAAKPAPDQTEATTNQAKQKGEKRKADPGWFEIDEGKNTNVYVSGLPPDITPEEFVGLMSKYGIVMRDPITEEYKVKLYKDKDGNLKGDGLCCYLKKESLELAVRLLDEYEVRGYKLHVEAAQFELK-GQYDASKKKKKSKDYKKKLQQQQKQLDWRPEKKGDVRKRHEKVVIIRNMFHPSDFEEDPLVLNEYREDLRTECEKFGGVKKVVLFDRHPDGVASVAFKEPEEADACVLSFNGRWFGGRQLIAHLWDGTTDYQV 365

[Close]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Medaka
Match: htatsf1 (HIV Tat-specific factor 1 [Source:NCBI gene;Acc:101155132])

HSP 1 Score: 166.007 bits (419), Expect = 1.042e-45
Identity = 125/367 (34.06%), Postives = 187/367 (50.95%), Query Frame = 1

Query:   61 MNDDICQEINNKIHPTTRID-EDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEEN--EFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKT-IRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKV 1149
            M++   Q  ++   P T  D  DG    WD EK+AWFP + D+FI  +  NYGF +KE +   N  AV                        +  P  + N+K        A +  K++    K      E+T    ++ K K    E    D   N  EFV L+SKYG++M +P T   KVKLYK+ DG  KGDG CCYLK ES+ LA+ LLD Y +RG  L V  A+FE K G     ++K  +K+ KK L++Q+    W PE K  +R + +  VI++N+F P+  +E+P +  + ++ +  E +  G VK +++ D HP+ V  + FK+   +D  V  FN + +  R + A +WDG T Y+V
Sbjct:   17 MHELYGQRKDDGSDPFTYTDPADGTVYDWDPEKKAWFPKVTDDFIAAYQANYGF-TKEGDPDTNAGAVSS----------------------SDPPAPEPNSK--------APEKAKSETSAAKPAPDQTEAT---TNQAKQKG---EKRKADPARNNFEFVGLMSKYGIVMRDPITEEYKVKLYKDKDGNLKGDGLCCYLKKESLELAVRLLDEYEVRGYKLHVEAAQFELK-GQYDASKKKKKSKDYKKKLQQQQKQLDWRPEKKGDVRKRHEKVVIIRNMFHPSDFEEDPLVLNEYREDLRTECEKFGGVKKVVLFDRHPDGVASVAFKEPEEADACVLSFNGRWFGGRQLIAHLWDGTTDYQV 345

[Close]

BLAST of HIV Tat-specific factor 1 vs. Planmine SMEST
Match: SMESG000021348.1 (SMESG000021348.1)

HSP 1 Score: 783.097 bits (2021), Expect = 0.000e+0
Identity = 443/444 (99.77%), Postives = 443/444 (99.77%), Query Frame = 1

Query:   61 MNDDICQEINNKIHPTTRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEXXXXXXXXXXXXXXXXAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPXXXXXXXXXXXXXXXXXQESLFRWGPETKTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETEDEEKVRXXXXXXXXXXXXXXGNIDEFPSENDIETENLEDVLKLLKGDCSVEGDKSNNSQIATSINEGSFEDTEEQDT 1392
            MNDDICQEINNKIHPTTRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEKYEKNKIKPKKRHHKPAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPKKRRKITNKEKKKLLKKQESLFRWGPETKTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETEDEEKVRIEKWEKLLEEEKIEGNIDEF SENDIETENLEDVLKLLKGDCSVEGDKSNNSQIATSINEGSFEDTEEQDT
Sbjct:    1 MNDDICQEINNKIHPTTRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLNYGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYNNKWYKFYSENAEKYEKNKIKPKKRHHKPAESTWFEIDENKNKNIYIENLPLDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKIESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPKKRRKITNKEKKKLLKKQESLFRWGPETKTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKISKETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHISAEIWDGRTKYKVKETEDEEKVRIEKWEKLLEEEKIEGNIDEFHSENDIETENLEDVLKLLKGDCSVEGDKSNNSQIATSINEGSFEDTEEQDT 444

The following BLAST results are available for this feature:

BLAST of HIV Tat-specific factor 1 vs. Ensembl Human
BLAST of HIV Tat-specific factor 1 vs. Ensembl Celegans
BLAST of HIV Tat-specific factor 1 vs. Ensembl Fly
BLAST of HIV Tat-specific factor 1 vs. Ensembl Zebrafish
BLAST of HIV Tat-specific factor 1 vs. Ensembl Xenopus
BLAST of HIV Tat-specific factor 1 vs. Ensembl Mouse
BLAST of HIV Tat-specific factor 1 vs. UniProt/SwissProt
BLAST of HIV Tat-specific factor 1 vs. TrEMBL
BLAST of HIV Tat-specific factor 1 vs. Ensembl Cavefish
BLAST of HIV Tat-specific factor 1 vs. Ensembl Sea Lamprey
BLAST of HIV Tat-specific factor 1 vs. Ensembl Yeast
BLAST of HIV Tat-specific factor 1 vs. Ensembl Nematostella
BLAST of HIV Tat-specific factor 1 vs. Ensembl Medaka
BLAST of HIV Tat-specific factor 1 vs. Planmine SMEST

BLAST of HIV Tat-specific factor 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4


Match Name	E-value	Identity	Description
HTATSF1	2.084e-47	35.33	HIV-1 Tat specific factor 1 [Source:HGNC Symbol;Ac...	[more]
HTATSF1	2.084e-47	35.33	HIV-1 Tat specific factor 1 [Source:HGNC Symbol;Ac...	[more]
HTATSF1	2.187e-28	40.24	HIV-1 Tat specific factor 1 [Source:HGNC Symbol;Ac...	[more]
HTATSF1	4.253e-28	40.61	HIV-1 Tat specific factor 1 [Source:HGNC Symbol;Ac...	[more]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
cus-2	3.843e-54	40.93	pep chromosome:WBcel235:I:654090:658810:1 gene:WBG...	[more]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2


Match Name	E-value	Identity	Description
barc	2.226e-54	40.08	gene:FBgn0037081 transcript:FBtr0078399	[more]
barc	2.226e-54	40.08	gene:FBgn0037081 transcript:FBtr0078400	[more]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
htatsf1	5.389e-57	37.05	HIV-1 Tat specific factor 1 [Source:ZFIN;Acc:ZDB-G...	[more]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of HIV Tat-specific factor 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Htatsf1	5.542e-51	33.24	HIV TAT specific factor 1 [Source:MGI Symbol;Acc:M...	[more]
Htatsf1	2.618e-25	33.17	HIV TAT specific factor 1 [Source:MGI Symbol;Acc:M...	[more]

BLAST of HIV Tat-specific factor 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q8BGC0\|HTSF1_MOUSE	3.877e-50	33.24	HIV Tat-specific factor 1 homolog OS=Mus musculus ...	[more]
sp\|O43719\|HTSF1_HUMAN	1.001e-46	35.33	HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 ...	[more]
sp\|Q5RB63\|HTSF1_PONAB	1.635e-46	35.33	HIV Tat-specific factor 1 homolog OS=Pongo abelii ...	[more]
sp\|O43120\|UAP2_SCHPO	4.790e-23	26.02	Splicing factor U2AF-associated protein 2 OS=Schiz...	[more]
sp\|P53830\|CUS2_YEAST	4.497e-8	30.77	Cold sensitive U2 snRNA suppressor 2 OS=Saccharomy...	[more]

BLAST of HIV Tat-specific factor 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A087UHQ3	4.270e-64	37.29	HIV Tat-specific factor 1 (Fragment) OS=Stegodyphu...	[more]
A0A1Y1KY94	1.829e-62	37.36	RRM domain-containing protein OS=Photinus pyralis ...	[more]
A0A1S3KG96	3.927e-62	45.27	HIV Tat-specific factor 1 homolog isoform X1 OS=Li...	[more]
Q7Q5Q6	4.036e-62	37.33	AGAP006266-PA OS=Anopheles gambiae OX=7165 GN=1276...	[more]
A0A1S3KFU8	4.069e-62	45.27	HIV Tat-specific factor 1 homolog isoform X2 OS=Li...	[more]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
htatsf1	5.656e-55	35.33	HIV-1 Tat specific factor 1 [Source:NCBI gene;Acc:...	[more]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of HIV Tat-specific factor 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
CUS2	6.476e-10	30.77	Putative checkpoint factor in transcription; binds...	[more]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO33511	1.779e-40	34.02	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of HIV Tat-specific factor 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
htatsf1	9.791e-59	35.92	HIV Tat-specific factor 1 [Source:NCBI gene;Acc:10...	[more]
htatsf1	1.042e-45	34.06	HIV Tat-specific factor 1 [Source:NCBI gene;Acc:10...	[more]

BLAST of HIV Tat-specific factor 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000021348.1	0.000e+0	99.77	SMESG000021348.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30023117 ID=SMED30023117|Name=HIV Tat-specific factor 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1464bp
ATTGTTTTAATAATAATTTTTAATTAATTGTAAATTATAATTTATTTTAT
TAAAGATACAATGAATGATGATATTTGCCAAGAAATTAATAATAAAATTC
ACCCAACAACTAGAATAGATGAGGATGGAATTGAAGTTAAATGGGATGAA
GAGAAGCAAGCATGGTTTCCTAATATTGACGATGAATTTATTTATAAACA
CAATTTGAATTATGGATTTCTTTCTAAGGAAGAAAATAAATCAGAAAACG
AAACAGCTGTAGTTCAACCAGAATGGTTCTTACGCCTAACAAAAGATTTT
TTAGACATTTGTCAATTGGAAAATGTAGATTTAACAACATTCCCTTTAGA
GGATTACAATAACAAATGGTATAAATTCTATTCTGAAAACGCTGAAAAAT
ATGAGAAAAATAAGATTAAACCCAAAAAACGTCACCACAAACCTGCTGAA
TCAACATGGTTTGAAATCGACGAGAACAAAAACAAAAATATTTATATTGA
AAATTTACCACTAGACATCGAGGAAAATGAATTTGTTGAATTAGTTTCAA
AGTATGGATTGTTGATGTATGAACCATTTACAAACATTCCCAAAGTCAAA
TTGTATAAAAATCCCGATGGCACTAATAAAGGCGATGGAAAATGTTGTTA
TTTAAAAATAGAGTCAATTAATTTGGCGTTGAATCTTTTGGATGGATATA
ATCTTCGAGGATGTATTTTAAAAGTCTCACGAGCTAAATTCGAGAAAAAA
GAAGGTTTTGATCCAAAAAAACGACGAAAAATTACCAACAAAGAGAAAAA
AAAGTTATTGAAAAAACAAGAAAGCCTATTTCGCTGGGGCCCCGAAACCA
AAACAATCCGGCCGAAAAAAGACAATACAGTTATTTTAAAGAATGTTTTT
GACCCAAATATAATGAAAGAAAATCCCGACTTAGCTATGGATATAAAAGA
TAAAATCAGCAAAGAAACCAAAAATATAGGTGCTGTGAAATCTATAATAG
TTCACGATTTACATCCTGAGGCGGTTGTTCAAATTAATTTTAAAGATGCA
AATCTATCTGATATCGCAGTTGAATATTTCAACAACAAATTGTGGAATAA
TCGACATATCAGTGCTGAAATCTGGGACGGTAGAACCAAATATAAAGTAA
AAGAAACTGAAGATGAAGAAAAAGTAAGAATAGAAAAATGGGAAAAACTA
CTTGAAGAAGAAAAGATTGAAGGAAATATTGACGAGTTTCCCTCGGAAAA
TGATATTGAAACTGAAAATCTGGAAGATGTTTTAAAATTACTTAAAGGTG
ATTGTTCAGTTGAAGGTGACAAGTCAAACAACTCTCAAATCGCTACATCT
ATCAATGAAGGATCTTTTGAGGACACCGAGGAACAGGACACGTGAATGTT
TTTTTAATAAACTGTTGTTGATAATTTTAGTAATACAAATAATTAATAAT
AAATATTTAATAAT

protein sequence of SMED30023117-orf-1

>SMED30023117-orf-1 ID=SMED30023117-orf-1|Name=SMED30023117-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=445bp
MNDDICQEINNKIHPTTRIDEDGIEVKWDEEKQAWFPNIDDEFIYKHNLN
YGFLSKEENKSENETAVVQPEWFLRLTKDFLDICQLENVDLTTFPLEDYN
NKWYKFYSENAEKYEKNKIKPKKRHHKPAESTWFEIDENKNKNIYIENLP
LDIEENEFVELVSKYGLLMYEPFTNIPKVKLYKNPDGTNKGDGKCCYLKI
ESINLALNLLDGYNLRGCILKVSRAKFEKKEGFDPKKRRKITNKEKKKLL
KKQESLFRWGPETKTIRPKKDNTVILKNVFDPNIMKENPDLAMDIKDKIS
KETKNIGAVKSIIVHDLHPEAVVQINFKDANLSDIAVEYFNNKLWNNRHI
SAEIWDGRTKYKVKETEDEEKVRIEKWEKLLEEEKIEGNIDEFPSENDIE
TENLEDVLKLLKGDCSVEGDKSNNSQIATSINEGSFEDTEEQDT*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0000398	mRNA splicing, via spliceosome

Vocabulary: **molecular function**
Term	Definition
GO:0003723	RNA binding
GO:0003676	nucleic acid binding
GO:0000166	nucleotide binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR034393	TatSF1-like
IPR034392	TatSF1-like_RRM1
IPR035979	RBD_domain_sf
IPR000504	RRM_dom
IPR012677	Nucleotide-bd_a/b_plait_sf

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 367..387
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 421..444
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 421..435
IPR000504	RNA recognition motif domain	SMART	SM00360	rrm1_1	coord: 143..223 e-value: 1.6E-5 score: 34.4
IPR000504	RNA recognition motif domain	PROSITE	PS50102	RRM	coord: 142..227 score: 11.042
IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	GENE3D	G3DSA:3.30.70.330		coord: 272..356 e-value: 4.9E-13 score: 50.9
IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	GENE3D	G3DSA:3.30.70.330		coord: 134..256 e-value: 1.4E-14 score: 56.2
IPR034393	TatSF1-like	PANTHER	PTHR15608	SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2	coord: 16..384
IPR034392	TatSF1-like, RNA recognition motif 1	CDD	cd12281	RRM1_TatSF1_like	coord: 141..231 e-value: 5.34564E-37 score: 128.42
IPR035979	RNA-binding domain superfamily	SUPERFAMILY	SSF54928	RNA-binding domain, RBD	coord: 294..358
IPR035979	RNA-binding domain superfamily	SUPERFAMILY	SSF54928	RNA-binding domain, RBD	coord: 126..234

Main menu

HIV Tat-specific factor 1

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Owlery

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