Glycine receptor subunit alpha-3
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30023116 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA3 (glycine receptor alpha 3 [Source:HGNC Symbol;Acc:HGNC:4328]) HSP 1 Score: 247.669 bits (631), Expect = 1.566e-75 Identity = 150/431 (34.80%), Postives = 242/431 (56.15%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSEL-WQRDVQNIVH----QELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W+ P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L ++R +N ++ +++S M + ++S + MG A+ T N Q++ SP+E + I + + +ID S+ FP F+++N FYW+ Y IL
Sbjct: 56 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQ------AKDGMTPKGPNH---------PVQVMPKSPDEMRKVFIDRAK----------KIDTISRACFPLAFLIFNIFYWVIYKIL 454
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA3 (glycine receptor alpha 3 [Source:HGNC Symbol;Acc:HGNC:4328]) HSP 1 Score: 243.432 bits (620), Expect = 4.564e-74 Identity = 145/426 (34.04%), Postives = 231/426 (54.23%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W+ P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ H+EL ++ + K + + A+ T N Q++ SP+E + I + + +ID S+ FP F+++N FYW+ Y IL
Sbjct: 56 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ--------------HKELLRFRRKRKNKDDEVRESRFSFTAYGMGPCLQ--AKDGMTPKGPNH---------PVQVMPKSPDEMRKVFIDRAK----------KIDTISRACFPLAFLIFNIFYWVIYKIL 439
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA2 (glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]) HSP 1 Score: 241.121 bits (614), Expect = 3.253e-73 Identity = 153/436 (35.09%), Postives = 236/436 (54.13%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDS----------EIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + SV M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG+VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W S P+ + + +P+F + C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L R Q ++E + ++ NF S H L+V ++A+P L PQ PP D+ ID S+ FP F+++N FYW+ Y I+
Sbjct: 57 GYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE------EDVTRESRFNF-------------------------SGYGMGHCLQV-KDGTAVKATPANPL------PQ---PPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKII 444
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA2 (glycine receptor alpha 2 [Source:HGNC Symbol;Acc:HGNC:4327]) HSP 1 Score: 240.736 bits (613), Expect = 6.009e-73 Identity = 152/436 (34.86%), Postives = 236/436 (54.13%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDS----------EIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG+VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W S P+ + + +P+F + C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L R Q ++E + ++ NF S H L+V ++A+P L PQ PP D+ ID S+ FP F+++N FYW+ Y I+
Sbjct: 57 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE------EDVTRESRFNF-------------------------SGYGMGHCLQV-KDGTAVKATPANPL------PQ---PPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKII 444
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Match: GLRA1 (glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326]) HSP 1 Score: 240.35 bits (612), Expect = 8.290e-73 Identity = 146/429 (34.03%), Postives = 237/429 (55.24%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA++ +++L + P + IW PDLFF N K + H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W+ + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L R + + + + NF + MG P + + +NS + N S S ++ + +Q +ID S+ FP F+++N FYW+ Y I+ R+
Sbjct: 51 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQEDEAGEGRFNF-SAYGMG-PACLQAKDGISVKGANNS------------------NTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRRE 452
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: glc-3 (Glutamate-gated ChLoride channel; Glutamate-gated chloride channel subunit [Source:UniProtKB/TrEMBL;Acc:G5EEZ3]) HSP 1 Score: 236.113 bits (601), Expect = 2.486e-71 Identity = 162/492 (32.93%), Postives = 255/492 (51.83%), Query Frame = 3
Query: 171 RKMIKCFSICFFFMSTTSLGTSMNSDREQIQNHIFKGYKSNERP--------SENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAW----DHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQ--IPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSI--------NFLQMHLMGTP-----KTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLR-----KSISKPQVSEPPVQIDS---EIDGYSQFLFPAFFMLYNCFYWLYY 1541
R ++ I F++ + S SD E I+ + KGY RP + IV V M + +I+ +D + MEYS + R+EW+D RLA+ D F ++IW+PD FF+N K + H + PN L+R+ +G +LYS +I+M SC M LQ +PMD Q C +D+ SY YT + +++RW+ +P+ L + +P F + NV T C+ S T+TG Y+C++ L+RQ YL YIP+ ++V+VSW++FW+ AVPAR+TLG+ TLL + TQA+G++A LP VSY KAIDVWI AC+ F+ GAL+EFA + IS +S ++R+ L +K AL ++ ++M L P ++ + ++++N N N+ +L +F N + ++I + + +D D S+ LFP F+ +N YW Y
Sbjct: 4 RSLLNILLIVAFWIVGGNCDAS--SDTEIIKKLLGKGYDWRVRPPGINLTIPGTHGAVIVYVNMLIRSISKIDDVNMEYSVQLTFREEWVDGRLAYGFPGDSTPDFLILTAG-------QQIWMPDSFFQNEKQAHKHDIDKPNVLIRIHRDGRILYSVRISMVLSCPMHLQYYPMDVQTCLIDLASYAYTENDIEYRWKKTDPVQLKKGLHSSLPSF-ELNNVDTTLCT--SKTNTGTYSCLRTVLELRRQFSYYLLQLYIPSTMLVIVSWVSFWLDRGAVPARVTLGVTTLLTMTTQASGINAKLPPVSYTKAIDVWIGACLTFIFGALLEFAWVTYISSRS---FYKRNKNCSSRNSLLIETKQALIIPNTVVAQFPEHPEEVEMGLAQAPDVWIRQSGNGKTVSRVNGHINHNNDEAAELIIFDAKH-----KNRRFVWWTNFRNIRLIRWIRNRLNVDDNAKRADLISRVLFPTLFVCFNFVYWTKY 475
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: glc-1 (Glutamate-gated chloride channel alpha [Source:UniProtKB/Swiss-Prot;Acc:G5EBR3]) HSP 1 Score: 230.335 bits (586), Expect = 2.645e-69 Identity = 147/431 (34.11%), Postives = 229/431 (53.13%), Query Frame = 3
Query: 255 QIQNHIF-KGYKSNERPSENKQ--TIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQ--IPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYW 1532
+I H+F GY RP + +V+V M + I+ +DV+ MEYS + LR+ WID+RL++ + + V +IW+PD FF N K Y H++ PN L+R+ +G VLYS +I++ SC M LQ +PMD Q+C++D+ SY YT +++ W+ P+ L + +P F Q TN T C+ S T+TG Y+C++ T L+R+ YL YIP+ ++V+VSW++FW A+PAR+TLG+ TLL + Q+ G+++ LP VSYIKAIDVWI AC+ F+ AL+EFA+ + I+ K E R +++ I LQ N ++ + +++ E T L N L +K + ++ I +D S+ LFP F ++N YW
Sbjct: 65 KILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQP---DFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSF-QLTNTSTTYCT--SVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANKQGVERKAR----------------TEREKAEIPLLQ------------------NLHNDVPTKVFNQEEKVRTVPLNRRQMNSFLNLLETKTEWND----ISKRVDLISRALFPVLFFVFNILYW 451
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: glc-1 (Glutamate-gated chloride channel alpha [Source:UniProtKB/Swiss-Prot;Acc:G5EBR3]) HSP 1 Score: 230.335 bits (586), Expect = 2.645e-69 Identity = 147/431 (34.11%), Postives = 229/431 (53.13%), Query Frame = 3
Query: 255 QIQNHIF-KGYKSNERPSENKQ--TIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQ--IPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYW 1532
+I H+F GY RP + +V+V M + I+ +DV+ MEYS + LR+ WID+RL++ + + V +IW+PD FF N K Y H++ PN L+R+ +G VLYS +I++ SC M LQ +PMD Q+C++D+ SY YT +++ W+ P+ L + +P F Q TN T C+ S T+TG Y+C++ T L+R+ YL YIP+ ++V+VSW++FW A+PAR+TLG+ TLL + Q+ G+++ LP VSYIKAIDVWI AC+ F+ AL+EFA+ + I+ K E R +++ I LQ N ++ + +++ E T L N L +K + ++ I +D S+ LFP F ++N YW
Sbjct: 65 KILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQP---DFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSF-QLTNTSTTYCT--SVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHIANKQGVERKAR----------------TEREKAEIPLLQ------------------NLHNDVPTKVFNQEEKVRTVPLNRRQMNSFLNLLETKTEWND----ISKRVDLISRALFPVLFFVFNILYW 451
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: avr-15 (pep chromosome:WBcel235:V:13498786:13502743:-1 gene:WBGene00000233.1 transcript:R11G10.1b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-15) HSP 1 Score: 226.098 bits (575), Expect = 1.504e-67 Identity = 150/444 (33.78%), Postives = 238/444 (53.60%), Query Frame = 3
Query: 240 NSDREQIQNHIFKGYKSNERPSENKQTI------VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQ--IPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVF-LTAQLLEASPNEKLRKSISKPQVSEPPVQIDSE-IDGYSQFLFPAFFMLYNCFYWLYY 1541
SD E +++ + +GY RP TI V+V M + +I+ +D + MEYS + R+ W+D+RL++ K + + L+ +E IW+PD FF+N K Y H + PN L+R+ +G +LYS +I++ SC M LQ +PMD Q+C +D+ SY YT +++ W+ P+ L + +P F Q TN T C+ S T+TG Y+C++ L+RQ YL YIP+ ++V+VSW++FW+ AVPAR+TLG+ TLL + TQ++G++A LP V+YIKAIDVWI AC+ F+ AL+EFA + I+ K +D E +++ + FLQ NS N+ + EV +++ N + S+ K ++ S+ D S+ +FP F+ +N YW +Y
Sbjct: 70 TSDTEILEHLLTRGYDHRVRPPGEDGTIHGGPVVVSVNMLLRSISKIDNVNMEYSVQLTFRESWVDKRLSFG--VKGDAQPDFLILTAGQE-IWMPDSFFQNEKQAYKHMIDKPNVLIRVHKDGTILYSVRISLVLSCPMHLQYYPMDVQQCFIDLASYAYTTKDIEYVWKEETPVQLKAGLSSSLPSF-QLTNTSTTYCT--SKTNTGSYSCLRTIIQLRRQFSYYLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINAKLPPVAYIKAIDVWIGACMTFIFCALLEFAWVTYIANK-------QDANKRARTE---------REKAELPFLQ----------------------NSHNDVWVPREVAEQEREVMTVRMNRRQTNSVWKWIKTKTEWNDKSKRADLISRVMFPVLFLTFNISYWTHY 469
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Match: avr-15 (pep chromosome:WBcel235:V:13498786:13502582:-1 gene:WBGene00000233.1 transcript:R11G10.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:avr-15) HSP 1 Score: 226.098 bits (575), Expect = 1.504e-67 Identity = 150/444 (33.78%), Postives = 238/444 (53.60%), Query Frame = 3
Query: 240 NSDREQIQNHIFKGYKSNERPSENKQTI------VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQ--IPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVF-LTAQLLEASPNEKLRKSISKPQVSEPPVQIDSE-IDGYSQFLFPAFFMLYNCFYWLYY 1541
SD E +++ + +GY RP TI V+V M + +I+ +D + MEYS + R+ W+D+RL++ K + + L+ +E IW+PD FF+N K Y H + PN L+R+ +G +LYS +I++ SC M LQ +PMD Q+C +D+ SY YT +++ W+ P+ L + +P F Q TN T C+ S T+TG Y+C++ L+RQ YL YIP+ ++V+VSW++FW+ AVPAR+TLG+ TLL + TQ++G++A LP V+YIKAIDVWI AC+ F+ AL+EFA + I+ K +D E +++ + FLQ NS N+ + EV +++ N + S+ K ++ S+ D S+ +FP F+ +N YW +Y
Sbjct: 70 TSDTEILEHLLTRGYDHRVRPPGEDGTIHGGPVVVSVNMLLRSISKIDNVNMEYSVQLTFRESWVDKRLSFG--VKGDAQPDFLILTAGQE-IWMPDSFFQNEKQAYKHMIDKPNVLIRVHKDGTILYSVRISLVLSCPMHLQYYPMDVQQCFIDLASYAYTTKDIEYVWKEETPVQLKAGLSSSLPSF-QLTNTSTTYCT--SKTNTGSYSCLRTIIQLRRQFSYYLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINAKLPPVAYIKAIDVWIGACMTFIFCALLEFAWVTYIANK-------QDANKRARTE---------REKAELPFLQ----------------------NSHNDVWVPREVAEQEREVMTVRMNRRQTNSVWKWIKTKTEWNDKSKRADLISRVMFPVLFLTFNISYWTHY 469
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335420) HSP 1 Score: 238.424 bits (607), Expect = 1.649e-72 Identity = 150/426 (35.21%), Postives = 237/426 (55.63%), Query Frame = 3
Query: 282 YKSNERPS-----ENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYL 1544
Y + RPS +NK T V+V M + +I+ +D KMEYS + R++W DERL +D I+ Y ++ ++W+PDLFF N K+G+ H++ PN +R+ PNG VLYS +I++ +C M+L+ +P+D Q C++ + SYG+T + L F W+ +P+ + + +P F + T C+ S T+TG+Y+C+K +R+ YL YIP ++V+VSW++FW+ AVPAR++LG+ TLL + TQ +G++A+LP VSY KAIDVW C+ FV GAL+EFA+ + SR +H+E K + L +Q S++ L+ T +F + + LE L ++ +P R + K +S+ P + ID S+ FP F L+N YW YL
Sbjct: 46 YDARIRPSGINGTDNKATNVSVNMFLRSISKIDDYKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKFL-TDYCN--SKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSD------------MHKENMKKKRRDL-EQASLD-AASDLLDTDSNATFAMKPLVRHPGDPL-----ALEKRLQCEVHMQAPK---RPNCCKTWLSKFPTR-SKRIDVISRITFPLVFALFNLVYWSTYL 441
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335418) HSP 1 Score: 238.424 bits (607), Expect = 2.345e-72 Identity = 152/429 (35.43%), Postives = 240/429 (55.94%), Query Frame = 3
Query: 282 YKSNERPS-----ENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDS---EIDGYSQFLFPAFFMLYNCFYWLYYL 1544
Y + RPS +NK T V+V M + +I+ +D KMEYS + R++W DERL +D I+ Y ++ ++W+PDLFF N K+G+ H++ PN +R+ PNG VLYS +I++ +C M+L+ +P+D Q C++ + SYG+T + L F W+ +P+ + + +P F + T C+ S T+TG+Y+C+K +R+ YL YIP ++V+VSW++FW+ AVPAR++LG+ TLL + TQ +G++A+LP VSY KAIDVW C+ FV GAL+EFA+ + SR + + +H+E K + L +Q S++ L T+S A + + LE L ++ +P R + K +S+ P + S ID S+ FP F L+N YW YL
Sbjct: 46 YDARIRPSGINGTDNKATNVSVNMFLRSISKIDDYKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKFL-TDYCN--SKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSN-------KANMHKENMKKKRRDL-EQASLDAASDLL----DTDSNATFAMKPLVRHPGDPL--ALEKRLQCEVHMQAPK---RPNCCKTWLSKFPTRQCSRSKRIDVISRITFPLVFALFNLVYWSTYL 450
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0343788) HSP 1 Score: 235.728 bits (600), Expect = 2.652e-71 Identity = 148/431 (34.34%), Postives = 236/431 (54.76%), Query Frame = 3
Query: 282 YKSNERPSENKQT----IVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHK------LEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYL 1544
Y + RPS T +V V + V +I+ +D + MEYS + R++W DERL +D I+ Y ++ ++W+PDLFF N K+G+ H++ PN +R+ PNG VLYS +I++ +C M+L+ +P+D Q C++ + SYG+T + L F W+ +P+ + + +P F + T C+ S T+TG+Y+C+K +R+ YL YIP ++V+VSW++FW+ AVPAR++LG+ TLL + TQ +G++A+LP VSY KAIDVW C+ FV GAL+EFA+ + SR + + +H+E K + L +Q S++ L+ T +F +Q LE L ++ +P R + K +S+ P + ID S+ FP F L+N YW YL
Sbjct: 46 YDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKFL-TDYCN--SKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSN-------KANMHKENMKKKRRDL-EQASLD-AASDLLDTDSNATFAMASQFARGGGQQKPLVRHPGDPLALEKRLQCEVHMQAPK---RPNCCKTWLSKFPTR-SKRIDVISRITFPLVFALFNLVYWSTYL 456
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0343790) HSP 1 Score: 234.572 bits (597), Expect = 5.909e-71 Identity = 151/425 (35.53%), Postives = 237/425 (55.76%), Query Frame = 3
Query: 282 YKSNERPSENKQT----IVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYL 1544
Y + RPS T +V V + V +I+ +D + MEYS + R++W DERL +D I+ Y ++ ++W+PDLFF N K+G+ H++ PN +R+ PNG VLYS +I++ +C M+L+ +P+D Q C++ + SYG+T + L F W+ +P+ + + +P F + T C+ S T+TG+Y+C+K +R+ YL YIP ++V+VSW++FW+ AVPAR++LG+ TLL + TQ +G++A+LP VSY KAIDVW C+ FV GAL+EFA+ + SR S S R +H+E K + L +Q S++ L T+S A + + LE L ++ +P R + K +S+ P + ID S+ FP F L+N YW YL
Sbjct: 46 YDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKFL-TDYCN--SKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASR-SGSNKANRAAD--MHKENMKKKRRDL-EQASLDAASDLL----DTDSNATFAMKPLVRHPGDPL--ALEKRLQCEVHMQAPK---RPNCCKTWLSKFPTR-SKRIDVISRITFPLVFALFNLVYWSTYL 449
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Match: GluClalpha (gene:FBgn0024963 transcript:FBtr0335416) HSP 1 Score: 233.032 bits (593), Expect = 1.905e-70 Identity = 148/425 (34.82%), Postives = 234/425 (55.06%), Query Frame = 3
Query: 282 YKSNERPSENKQT----IVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYL 1544
Y + RPS T +V V + V +I+ +D + MEYS + R++W DERL +D I+ Y ++ ++W+PDLFF N K+G+ H++ PN +R+ PNG VLYS +I++ +C M+L+ +P+D Q C++ + SYG+T + L F W+ +P+ + + +P F + T C+ S T+TG+Y+C+K +R+ YL YIP ++V+VSW++FW+ AVPAR++LG+ TLL + TQ +G++A+LP VSY KAIDVW C+ FV GAL+EFA+ + SR +H+E K + L +Q S++ L T+S A + + LE L ++ +P R + K +S+ P + ID S+ FP F L+N YW YL
Sbjct: 46 YDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKFL-TDYCN--SKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSD------------MHKENMKKKRRDL-EQASLDAASDLL----DTDSNATFAMKPLVRHPGDPL--ALEKRLQCEVHMQAPK---RPNCCKTWLSKFPTR-SKRIDVISRITFPLVFALFNLVYWSTYL 440
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra3 (glycine receptor, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-020402-1]) HSP 1 Score: 242.662 bits (618), Expect = 5.452e-74 Identity = 146/426 (34.27%), Postives = 235/426 (55.16%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K + H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W+ P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G +LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ H+EL ++ + K + + L TP N+ + A + +N+A + +E++RK + +ID S+ FP F+ +N FYW+ Y IL
Sbjct: 56 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEKGPVQVADGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ--------------HKELLRFRRRRKKSGKEEEVRESRLSFTP--NAGKDGAVPKTANNAATTPSE-------PAVAPGKSHEEMRKLF---------IDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 442
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 241.121 bits (614), Expect = 1.783e-73 Identity = 149/438 (34.02%), Postives = 239/438 (54.57%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQEL--FKWSKMALKKQQSINF---LQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIE 1571
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + I+R+ H+EL F+ + LK+ ++ + + MG + +A + +N+ +P EK + + K +S ID S+ FP F+++N FYW+ Y I +R +I
Sbjct: 47 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQ--------------HKELLRFQRRRRHLKEDEAGDGRFSFAAYGMGPACLQAKDGMAIKGNNNNAPT---------------STNPPEKTVEEMRKLFISRA-----KRIDTVSRVAFPLVFLIFNIFYWITYKI-IRSEDIH 442
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra4b (glycine receptor, alpha 4b [Source:ZFIN;Acc:ZDB-GENE-020402-2]) HSP 1 Score: 240.35 bits (612), Expect = 4.971e-73 Identity = 149/437 (34.10%), Postives = 236/437 (54.00%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVS--PLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIEMGL 1580
GY + RP+ + VT + + + S+ M+Y +V+LRQ+W D RLA ++ Y ++ + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMDTQ C M + S+GYT++ L F+W P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++L V++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ ++E F+ + +Q+ N ++ G S S D +E A + P I + V + ID S+ +FP F+++N FYW+ Y +L R +I + L
Sbjct: 68 GYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLA------YKEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCTMQLESFGYTMNDLIFQWLDEGPVQVADDLMLPQFVLKEEKDLGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ--------------YKEFFRLRRKL--RQEQRNRADLYFPGFGIDTSL-------SGDGPLSE---------AAAMFAGLPPGHALFDIRRRFVEQA-----KRIDTISRAVFPLSFLVFNVFYWVTYKVL-RNEDIHLAL 458
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 240.35 bits (612), Expect = 5.739e-73 Identity = 148/438 (33.79%), Postives = 238/438 (54.34%), Query Frame = 3
Query: 276 KGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQEL--FKWSKMALKKQQSINF---LQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIE 1571
+G KS+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + I+R+ H+EL F+ + LK+ ++ + + MG + +A + +N+ +P EK + + K +S ID S+ FP F+++N FYW+ Y I +R +I
Sbjct: 60 QGSKSDGTHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQ--------------HKELLRFQRRRRHLKEDEAGDGRFSFAAYGMGPACLQAKDGMAIKGNNNNAPT---------------STNPPEKTVEEMRKLFISRA-----KRIDTVSRVAFPLVFLIFNIFYWITYKI-IRSEDIH 455
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Match: glra4b (glycine receptor, alpha 4b [Source:ZFIN;Acc:ZDB-GENE-020402-2]) HSP 1 Score: 239.58 bits (610), Expect = 6.836e-73 Identity = 148/437 (33.87%), Postives = 239/437 (54.69%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVS--PLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIEMGL 1580
GY + RP+ + VT + + + S+ M+Y +V+LRQ+W D RLA ++ Y ++ + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMDTQ C M + S+GYT++ L F+W P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++L V++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ ++E F+ + ++Q++ + + P T+L+ +A F A L +R+ V+ ID S+ +FP F+++N FYW+ Y +L R +I + L
Sbjct: 51 GYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLA------YKEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCTMQLESFGYTMNDLIFQWLDEGPVQVADDLMLPQFVLKEEKDLGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ--------------YKEFFRLRRKLRQEQRNRD------LYFPGFGIDTSLSGDGPLSEAAAMF---------AGLPPGHALFDIRRRF---------VEQAKRIDTISRAVFPLSFLVFNVFYWVTYKVL-RNEDIHLAL 440
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: GLRA1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:100498379]) HSP 1 Score: 244.202 bits (622), Expect = 2.169e-74 Identity = 158/471 (33.55%), Postives = 253/471 (53.72%), Query Frame = 3
Query: 201 FFFMSTTSLGTSMNSDREQIQNHIF--------KGYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFT----NLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIE 1571
FF ++ +G S S + + F GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ STG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K EL + + H K +N LQ + SF A + + D + + + +AQ + SP+E + IS+ + +ID S+ FP F+++N FYW+ Y I VR ++
Sbjct: 11 FFLAASKEVGASARSSAKLMSPSDFLDKLMGKISGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTK--HYSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK-ELLRFRRRRRHH------------KSPMLNLLQEDENAEGRF-SFAAYGMGPACLQAKDGISMKGNNNNNPASSAQPVSKSPDEMRKLFISRAK----------KIDKVSRIGFPLVFLIFNTFYWIIYKI-VRSEDVH 449
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: GLRA1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:100498379]) HSP 1 Score: 243.817 bits (621), Expect = 3.568e-74 Identity = 157/475 (33.05%), Postives = 255/475 (53.68%), Query Frame = 3
Query: 177 MIKCFSICFFFMSTTSLGTSMNSDREQIQNHIF--------KGYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIE 1571
+I S F ++ +G S S + + F GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ STG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K EL + + H+E + +F + MG A + + D + + + +AQ + SP+E + IS+ + +ID S+ FP F+++N FYW+ Y I VR ++
Sbjct: 11 IIPIVSAMIFLAASKEVGASARSSAKLMSPSDFLDKLMGKISGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTK--HYSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK-ELLRFRRRRRHHKE-------DENAEGRFSF-AAYGMGP---------ACLQAKDGISMKGNNNNNPASSAQPVSKSPDEMRKLFISRAK----------KIDKVSRIGFPLVFLIFNTFYWIIYKI-VRSEDVH 449
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: GLRA1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:100498379]) HSP 1 Score: 242.276 bits (617), Expect = 1.231e-73 Identity = 150/433 (34.64%), Postives = 242/433 (55.89%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIE 1571
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ STG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K EL + + H+E + +F + MG A + + D + + + +AQ + SP+E + IS+ + +ID S+ FP F+++N FYW+ Y I VR ++
Sbjct: 51 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTK--HYSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK-ELLRFRRRRRHHKE-------DENAEGRFSF-AAYGMGP---------ACLQAKDGISMKGNNNNNPASSAQPVSKSPDEMRKLFISRAK----------KIDKVSRIGFPLVFLIFNTFYWIIYKI-VRSEDVH 447
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: GLRA1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:100498379]) HSP 1 Score: 241.506 bits (615), Expect = 1.325e-73 Identity = 150/433 (34.64%), Postives = 242/433 (55.89%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIE 1571
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ STG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K EL + + H+E + +F + MG A + + D + + + +AQ + SP+E + IS+ + +ID S+ FP F+++N FYW+ Y I VR ++
Sbjct: 34 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTK--HYSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK-ELLRFRRRRRHHKE-------DENAEGRFSF-AAYGMGP---------ACLQAKDGISMKGNNNNNPASSAQPVSKSPDEMRKLFISRAK----------KIDKVSRIGFPLVFLIFNTFYWIIYKI-VRSEDVH 430
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Match: GLRA1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:100498379]) HSP 1 Score: 241.891 bits (616), Expect = 1.701e-73 Identity = 150/433 (34.64%), Postives = 242/433 (55.89%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIE 1571
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ STG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K EL + + H+E + +F + MG A + + D + + + +AQ + SP+E + IS+ + +ID S+ FP F+++N FYW+ Y I VR ++
Sbjct: 52 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTK--HYSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK-ELLRFRRRRRHHKE-------DENAEGRFSF-AAYGMGP---------ACLQAKDGISMKGNNNNNPASSAQPVSKSPDEMRKLFISRAK----------KIDKVSRIGFPLVFLIFNTFYWIIYKI-VRSEDVH 448
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra3 (glycine receptor, alpha 3 subunit [Source:MGI Symbol;Acc:MGI:95749]) HSP 1 Score: 246.128 bits (627), Expect = 5.817e-75 Identity = 145/434 (33.41%), Postives = 237/434 (54.61%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEA-------SPNEKLRKSISKP-QVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W+ P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ H+EL ++ + K ++ + + + + TD+ E + L+A PN ++ P ++ + + +ID S+ FP F+++N FYW+ Y IL
Sbjct: 72 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ--------------HKELLRFRRKRKNKTEAFALEKFY--------------RFSDTDDEVRESRFSFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 470
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747]) HSP 1 Score: 241.891 bits (616), Expect = 1.424e-73 Identity = 147/429 (34.27%), Postives = 238/429 (55.48%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA++ +++L + P + IW PDLFF N K + H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W+ + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L R + + + + NF + MG A + + D + + + SP E++RK +Q +ID S+ FP F+++N FYW+ Y I+ R+
Sbjct: 51 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQDDEGGEGRFNF-SAYGMGP---------ACLQAKDGISVKGANNNNTTNPPPAPSKSP-EEMRKLF---------IQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRRE 452
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra2 (glycine receptor, alpha 2 subunit [Source:MGI Symbol;Acc:MGI:95748]) HSP 1 Score: 241.506 bits (615), Expect = 1.905e-73 Identity = 155/436 (35.55%), Postives = 240/436 (55.05%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDS----------EIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + SV M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG+VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W S P+ + + +P+F + C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L R Q ++E + ++ NF + MG + QM D +A ++A+P L PQ PP D+ ID S+ FP F+++N FYW+ Y I+
Sbjct: 57 GYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE------EDVTRESRFNF-SGYGMG--------HCLQMK--DGTA---------------VKATPANPL------PQ---PPKDADAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKII 444
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747]) HSP 1 Score: 238.424 bits (607), Expect = 2.613e-72 Identity = 147/429 (34.27%), Postives = 237/429 (55.24%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA++ +++L + P + IW PDLFF N K + H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W+ + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L R + + + NF + MG A + + D + + + SP E++RK +Q +ID S+ FP F+++N FYW+ Y I+ R+
Sbjct: 51 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKDD--------EGGEGRFNF-SAYGMGP---------ACLQAKDGISVKGANNNNTTNPPPAPSKSP-EEMRKLF---------IQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRRE 444
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Match: Glra1 (glycine receptor, alpha 1 subunit [Source:MGI Symbol;Acc:MGI:95747]) HSP 1 Score: 234.187 bits (596), Expect = 1.142e-71 Identity = 141/396 (35.61%), Postives = 223/396 (56.31%), Query Frame = 3
Query: 375 MEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
M+Y +++LRQ+W D RLA++ +++L + P + IW PDLFF N K + H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W+ + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L R + + + NF + MG A + + D + + + SP E++RK +Q +ID S+ FP F+++N FYW+ Y I+ R+
Sbjct: 1 MDYRVNIFLRQQWNDPRLAYNEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKDD--------EGGEGRFNF-SAYGMGP---------ACLQAKDGISVKGANNNNTTNPPPAPSKSP-EEMRKLF---------IQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRRE 361
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|O75311|GLRA3_HUMAN (Glycine receptor subunit alpha-3 OS=Homo sapiens OX=9606 GN=GLRA3 PE=1 SV=2) HSP 1 Score: 247.669 bits (631), Expect = 7.519e-75 Identity = 150/431 (34.80%), Postives = 242/431 (56.15%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSEL-WQRDVQNIVH----QELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W+ P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L ++R +N ++ +++S M + ++S + MG A+ T N Q++ SP+E + I + + +ID S+ FP F+++N FYW+ Y IL
Sbjct: 56 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQ------AKDGMTPKGPNH---------PVQVMPKSPDEMRKVFIDRAK----------KIDTISRACFPLAFLIFNIFYWVIYKIL 454
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|Q91XP5|GLRA3_MOUSE (Glycine receptor subunit alpha-3 OS=Mus musculus OX=10090 GN=Glra3 PE=1 SV=2) HSP 1 Score: 246.514 bits (628), Expect = 1.910e-74 Identity = 145/434 (33.41%), Postives = 237/434 (54.61%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEA-------SPNEKLRKSISKP-QVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W+ P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ H+EL ++ + K ++ + + + + TD+ E + L+A PN ++ P ++ + + +ID S+ FP F+++N FYW+ Y IL
Sbjct: 56 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ--------------HKELLRFRRKRKNKTEAFALEKFY--------------RFSDTDDEVRESRFSFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 454
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|P24524|GLRA3_RAT (Glycine receptor subunit alpha-3 OS=Rattus norvegicus OX=10116 GN=Glra3 PE=1 SV=1) HSP 1 Score: 245.358 bits (625), Expect = 6.056e-74 Identity = 148/435 (34.02%), Postives = 236/435 (54.25%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEA-------SPNEKLRKSISKPQVSEPPVQID--SEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W+ P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ H+EL ++ + K ++ + + + TD+ E + L+A PN + + + K V ID +ID S+ FP F+++N FYW+ Y IL
Sbjct: 56 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ--------------HKELLRFRRKRKNKTEAF--------------ALEKFYRFSDTDDEVRESRLSFTAYGMGPCLQAKDGVVPKGPNHAV-QVMPKSADEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 454
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|Q64018|GLRA1_MOUSE (Glycine receptor subunit alpha-1 OS=Mus musculus OX=10090 GN=Glra1 PE=1 SV=2) HSP 1 Score: 241.891 bits (616), Expect = 9.959e-73 Identity = 147/429 (34.27%), Postives = 238/429 (55.48%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA++ +++L + P + IW PDLFF N K + H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W+ + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L R + + + + NF + MG A + + D + + + SP E++RK +Q +ID S+ FP F+++N FYW+ Y I+ R+
Sbjct: 51 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQDDEGGEGRFNF-SAYGMGP---------ACLQAKDGISVKGANNNNTTNPPPAPSKSP-EEMRKLF---------IQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRRE 452
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Match: sp|P07727|GLRA1_RAT (Glycine receptor subunit alpha-1 OS=Rattus norvegicus OX=10116 GN=Glra1 PE=1 SV=4) HSP 1 Score: 241.891 bits (616), Expect = 1.205e-72 Identity = 148/429 (34.50%), Postives = 239/429 (55.71%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA++ +++L + P + IW PDLFF N K + H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W+ + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L R + + + + NF + MG A + + D + + + A SP E++RK +Q +ID S+ FP F+++N FYW+ Y I+ R+
Sbjct: 51 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQDDEGGEGRFNF-SAYGMGP---------ACLQAKDGISVKGANNNNTTNPAPAPSKSP-EEMRKLF---------IQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRRE 452
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A183SPC0 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS6068 PE=3 SV=1) HSP 1 Score: 469.929 bits (1208), Expect = 3.290e-158 Identity = 238/439 (54.21%), Postives = 314/439 (71.53%), Query Frame = 3
Query: 249 REQIQNHIFKGYKSNERPSE--NKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
R+++ +F YK++ERP+E + T+V V MKVLAI SVDV M+Y D LRQ W D RLAWD ++F ++ LVSP KE +WLPDLFFRNGKDGY+H MT PNYLLR+ PNG VLYSQKITM+FSCQMDLQTFPMDTQ C+M+IGSYGYTL++LKF WR P+ LP +QI EFN P+N TIDC+ +SSTSTG+YTC+ A F L+RQLGSYL +TYIPN+LI+MVSWL+F+VS+DA PAR+ LGLL+LLG+LTQA+ ++ANLPRVSYIKAID+W+I I+FVI L+E+AIA + R+ + E W+ DV++IV +EL +W + Q + L+ +G + F FY+ L++FLT ++E S + + I P +SEID YS+FLFP +++YN FYWLYYL++V++
Sbjct: 82 RDRLVGMLFSNYKTHERPTELLDMATVVEVNMKVLAIFSVDVRTMDYYIDALLRQTWTDPRLAWDTSKEFENFTQALVSPTLKESLWLPDLFFRNGKDGYLHKMTLPNYLLRVYPNGNVLYSQKITMRFSCQMDLQTFPMDTQHCHMNIGSYGYTLNELKFAWRPENPVELPDKLQISEFNTPSNFTTIDCTAMSSTSTGNYTCLMAKFALKRQLGSYLVTTYIPNILIIMVSWLSFYVSVDAAPARVPLGLLSLLGLLTQASSVTANLPRVSYIKAIDLWLIFSIIFVISVLVEYAIAITLLRRKRRENWRNDVESIVKEELARWCAACQQTQLANMQLKSGAVGHELSQQFA--------------FYNDLDLFLTRTVIEESQKKSRKTKI--------PEATESEIDAYSRFLFPTCYIMYNVFYWLYYLVIVKQ 498
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A3P7LGN4 (Ig-like domain-containing protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS11906 PE=3 SV=1) HSP 1 Score: 468.389 bits (1204), Expect = 1.463e-157 Identity = 238/439 (54.21%), Postives = 310/439 (70.62%), Query Frame = 3
Query: 249 REQIQNHIFKGYKSNERPSE--NKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
R+++ +F YK++ERP+E + T+V V MKVLAI SVDV M+Y D LRQ W D RLAWD ++F ++ LVSP KE +WLPDLFFRNGKDGY+H MT PNYLLR+ PNG VLYSQKITM+FSCQMDLQTFPMDTQ C+M+IGSYGYTL++LKF WR P+ LP +QI EFN P+N TIDC+ +SSTSTG+YTC+ A F L+RQLGSYL +TYIPN+LI+MVSWL+F+VS+DA PAR+ LGLL+LLG+LTQA+ ++ANLPRVSYIKAID+W+I I+FVI L+E+AIA + R+ + E W+ DV+ IV +EL +W Q M L + F+ FY+ L++FLT ++E S + + I P +SEID YS+FLFP +++YN FYWLYYL++V++
Sbjct: 85 RDRLVGMLFSNYKTHERPTELLDVATVVEVNMKVLAIFSVDVRTMDYYIDALLRQTWTDPRLAWDTSKEFENFTQALVSPTLKESLWLPDLFFRNGKDGYLHKMTLPNYLLRVYPNGHVLYSQKITMRFSCQMDLQTFPMDTQHCHMNIGSYGYTLNELKFTWRPESPVELPDKLQISEFNTPSNFTTIDCTAMSSTSTGNYTCLMAKFALKRQLGSYLVTTYIPNILIIMVSWLSFYVSVDAAPARVPLGLLSLLGLLTQASSVTANLPRVSYIKAIDLWLIFSIIFVISVLVEYAIAITLLRRKRRENWRNDVETIVKEELARWCAAC----QQTQLANMQLNSGAVAHEFSQ----------QFAFYNDLDLFLTRTVIEESQKKSRKTKI--------PEATESEIDAYSRFLFPTCYIMYNVFYWLYYLVIVKQ 501
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A068YF69 (Glycine receptor subunit alpha 1 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_001119800 PE=3 SV=1) HSP 1 Score: 463.766 bits (1192), Expect = 2.800e-156 Identity = 239/441 (54.20%), Postives = 314/441 (71.20%), Query Frame = 3
Query: 243 SDREQIQNHIFKGYKSNERPSE--NKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
+ R+++ +F YK++ERP+E + T+V + MKVLAI SVDV M+Y D LRQ W D RLAW+H E F++Y LVSP KE +WLPDLFFRNGKDGY+H MT PNYLLR+ PNGEVLYSQKITM+FSCQMDL TFPMDTQ C+M+IGSYGYTL +LKF WR EP+ L +Q+ EFN PTN T+DC+ SSTSTG+YTC+ A F L+RQLGSYL +TYIPN+LI+MVSWL+F+VS+DA PAR+ LGLL+LLG+LTQA+ ++ NLPRVSYIKAID+W+I I+FVIG L+E+AIA + R+ + E W+ DV+ IV +EL +W +A +Q + +Q G+ Q +++ L+ FLT ++E + +K K S PV ++SEID YS+FLFP +++YN FYW YYL +V+K
Sbjct: 56 TQRDRLVGMLFANYKTHERPTEKLDIPTVVEINMKVLAIFSVDVRTMDYYIDALLRQTWTDPRLAWNHREGFKNYTQPLVSPTLKENLWLPDLFFRNGKDGYLHKMTLPNYLLRVHPNGEVLYSQKITMRFSCQMDLATFPMDTQYCHMNIGSYGYTLSELKFVWREKEPVELQNNLQLSEFNTPTNFTTLDCTAQSSTSTGNYTCLMAQFSLKRQLGSYLVTTYIPNILIIMVSWLSFYVSVDAAPARVPLGLLSLLGLLTQASSITGNLPRVSYIKAIDLWLIFSIIFVIGVLVEYAIAITMLRQKRKETWRGDVELIVKEELTRW--LAACEQGQMASIQ----GSGGVRGDQGFIQQQLA------YFNDLDAFLTKSVIEETRAKKGDKK------SRVPVAVESEIDAYSRFLFPTCYIMYNIFYWTYYLAIVKK 478
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: A0A0R3X4J8 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS8324 PE=3 SV=1) HSP 1 Score: 463.766 bits (1192), Expect = 7.274e-156 Identity = 239/441 (54.20%), Postives = 314/441 (71.20%), Query Frame = 3
Query: 243 SDREQIQNHIFKGYKSNERPSE--NKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
+ R+++ +F YK++ERP+E + T+V + MKVLAI SVDV M+Y D LRQ WID RLAW+H E F++Y LVSP KE +WLPDLFFRNGKDGY+H MT PNYLLR+ PNGEVLYSQKITM+FSCQMDL TFPMDTQ C+M+IGSYGYTL +LKF WR EP+ L +Q+ EFN PTN T+DC+ SSTSTG+YTC+ A F L+RQLGSYL +TYIPN+LI+MVSWL+F+VS+DA PAR+ LGLL+LLG+LTQA+ ++ NLPRVSYIKAID+W+I I+FVIG L+E+AIA + R+ + E W+ DV+ IV +EL +W + Q + M G + + Q+ +++ L+ FLT ++E + +K K S PV ++SEID YS+FLFP +++YN FYW YYL +V+K
Sbjct: 76 TQRDRLVGMLFANYKTHERPTEKLDIPTVVEINMKVLAIFSVDVRTMDYYIDALLRQTWIDPRLAWNHREDFQNYTQPLVSPTLKENLWLPDLFFRNGKDGYLHKMTLPNYLLRVHPNGEVLYSQKITMRFSCQMDLATFPMDTQYCHMNIGSYGYTLSELKFIWREKEPVELQNNLQLSEFNTPTNFTTLDCTAQSSTSTGNYTCLMAQFSLKRQLGSYLVTTYIPNILIIMVSWLSFYVSVDAAPARVPLGLLSLLGLLTQASSITGNLPRVSYIKAIDLWLIFSIIFVIGVLVEYAIAITMLRQKRKETWRGDVELIVKEELTRWLAACEQSQMA----SMQGSGCVRGDQGFIQQQL--------AYFNDLDAFLTKSVIEETRAKKGGKK------SRIPVAVESEIDAYSRFLFPTCYIMYNIFYWTYYLAIVKK 498
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Match: U6J8V0 (Glycine receptor subunit alpha 1 OS=Echinococcus granulosus OX=6210 GN=EGR_05559 PE=3 SV=1) HSP 1 Score: 462.611 bits (1189), Expect = 1.055e-155 Identity = 238/441 (53.97%), Postives = 314/441 (71.20%), Query Frame = 3
Query: 243 SDREQIQNHIFKGYKSNERPSE--NKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRK 1559
+ R+++ +F YK++ERP+E + T+V + MKVLAI SVDV M+Y D LRQ W D RLAW+H E F++Y LVSP KE +WLPDLFFRNGKDGY+H MT PNYLLR+ PNGEVLYSQKITM+FSCQMDL TFPMDTQ C+M+IGSYGYTL +L+F WR EP+ L +Q+ EFN PTN T+DC+ SSTSTG+YTC+ A F L+RQLGSYL +TYIPN+LI+MVSWL+F+VS+DA PAR+ LGLL+LLG+LTQA+ ++ NLPRVSYIKAID+W+I I+FVIG L+E+AIA + R+ + E W+ DV+ IV +EL +W +A +Q + +Q G+ Q +++ L+ FLT ++E + +K K S PV ++SEID YS+FLFP +++YN FYW YYL +V+K
Sbjct: 56 TQRDRLVGMLFANYKTHERPTEKLDIPTVVEINMKVLAIFSVDVRTMDYYIDALLRQTWTDPRLAWNHREGFKNYTQPLVSPTLKENLWLPDLFFRNGKDGYLHKMTLPNYLLRVHPNGEVLYSQKITMRFSCQMDLATFPMDTQYCHMNIGSYGYTLSELQFVWREKEPVELQNNLQLSEFNTPTNFTTLDCTAQSSTSTGNYTCLMAKFSLKRQLGSYLVTTYIPNILIIMVSWLSFYVSVDAAPARVPLGLLSLLGLLTQASSITGNLPRVSYIKAIDLWLIFSIIFVIGVLVEYAIAITMLRQKRKETWRGDVELIVKEELTRW--LAACEQGQMASIQ----GSGGVRGDQGFIQQQLA------YFNDLDAFLTKSVIEEARAKKGDKK------SRVPVAVESEIDAYSRFLFPTCYIMYNIFYWTYYLAIVKK 478
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:103026517]) HSP 1 Score: 241.506 bits (615), Expect = 1.457e-73 Identity = 147/427 (34.43%), Postives = 235/427 (55.04%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSEL-WQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + I+R+ K L +QR +++ E + +F + MG + +A + +N+ + P EK + + K +S ID S+ FP F+++N FYW+ Y I+
Sbjct: 50 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFQRRRRHLKEDE---------AGEGRFSF-AAYGMGPACLQAKDGMAIKGNNNNAPT---------------SSIPPEKTVEEMRKLFISRA-----KRIDTVSRVAFPLVFLIFNIFYWIIYKII 439
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:103026517]) HSP 1 Score: 239.965 bits (611), Expect = 7.300e-73 Identity = 146/427 (34.19%), Postives = 234/427 (54.80%), Query Frame = 3
Query: 276 KGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSEL-WQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
+G KS+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + I+R+ K L +QR +++ E + +F + MG + +A + +N+ + P EK + + K +S ID S+ FP F+++N FYW+ Y I+
Sbjct: 63 QGSKSDGTHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFQRRRRHLKEDE---------AGEGRFSF-AAYGMGPACLQAKDGMAIKGNNNNAPT---------------SSIPPEKTVEEMRKLFISRA-----KRIDTVSRVAFPLVFLIFNIFYWIIYKII 452
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra3 (glycine receptor, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-020402-1]) HSP 1 Score: 240.35 bits (612), Expect = 1.007e-72 Identity = 148/445 (33.26%), Postives = 243/445 (54.61%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKS---ELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPP--------------VQID--SEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K + H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W++ P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G +LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K +R +H F+ + + QS+N L+ + ++ QM+ +++ E F + + + + S P+ P + ID +ID S+ FP F+ +N FYW+ Y IL
Sbjct: 55 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQANGPVQVADGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRKKSTKLHDRSFE--EELSESLQSVNGLR------SADPVYGSMDQMSESNDREEEVRESCLSFTANAGKDGTMTKPTNNAASTPKGQPTPTVPQAGKSTEEMRKIFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 484
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1]) HSP 1 Score: 238.039 bits (606), Expect = 2.196e-72 Identity = 147/428 (34.35%), Postives = 234/428 (54.67%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKS--ELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + SV M+Y +++LRQ+W D RLA+ + +L + P + IW PDLFF N K H +TT N LLR+ +G VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W P+ + + +P+F + C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L +R +N+ +EL ++ +F + K + A N+ + L +A N K K + + + ID S+ FP F+++N FYW+ Y I+
Sbjct: 45 GYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQKWNDPRLAYSEYP-----DPSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKDGTVLYSIRLTLILSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLDEGPVQVAEGLTLPQFIMREEKELGYCTK--HYNTGKFTCIEVKFKLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGVNFVSRQQKEFLRLKRRQKRNL-KEEL---------REGRFHFSGYSMAPCMKDGTVVKSATANAIQQP-------------SALRDAEHNRK--KFVDRAK----------RIDTISRAAFPLAFLIFNIFYWITYKII 430
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Match: glra3 (glycine receptor, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-020402-1]) HSP 1 Score: 238.039 bits (606), Expect = 3.264e-72 Identity = 148/433 (34.18%), Postives = 237/433 (54.73%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQ-----ID--SEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K + H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W++ P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G +LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ H+EL ++ + K + + L SFT A + T +T A+ K + + + PQ + + ID +ID S+ FP F+ +N FYW+ Y IL
Sbjct: 55 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQANGPVQVADGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ--------------HKELLRFRRRRKKSTKEEEVRESCL-------SFTANAGKDGT--------------MTKPTNNAASTPKGQPTPTVPQAGKSTEEMRKIFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 445
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008467.1 (pep scaffold:Pmarinus_7.0:GL477211:8305:20106:1 gene:ENSPMAG00000007648.1 transcript:ENSPMAT00000008467.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 251.136 bits (640), Expect = 7.964e-78 Identity = 149/443 (33.63%), Postives = 240/443 (54.18%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDH--IEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKS-----KSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIEMGLI 1583
GY RP+ + V+ + + + S+ +Y VYLRQ W D RLA+ H + +N+ + IW PDLFF N K + H +TT N +LR+ NG V Y+ ++T+ SC MDL FPMDTQ C+M + S+GYT + F W P+ L + +P+F + T C++ + STG +TCI A F L R++G YL Y+P++LIV++SW++FW++++A PAR+ LG+ T+L + TQ+TG A+LP+VSYIKA+D+W+ C+LFV AL+E+A ++ SR+S K Q+ + +VH+++F W + + + + + + L + +S ++ L+ Q EK+RK V ID S+ FP F+++N YW + +++ KRN+ +G I
Sbjct: 55 GYNHRVRPNFGGPAVNVSCGVFIRSFGSIQEATSDYRMTVYLRQRWTDPRLAYSHYPVPLLHLDQSNI------KHIWKPDLFFDNEKSAHFHEITTDNKMLRIANNGVVDYAMRLTLTLSCPMDLHNFPMDTQMCSMYLESFGYTTADIVFHWNGPTPVSLFEGLTLPQFVLSNKISTGSCTK--TYSTGSFTCIFAKFTLHREMGFYLIQLYVPSILIVILSWVSFWINMEAAPARVALGITTVLTLTTQSTGARASLPKVSYIKAMDIWMATCLLFVFAALLEYAAVNVTSRQSQGFMKKGRGNQKPIDLLVHKKMF-WKFLVAENDNDLLYFTITIF---------TLNGLLPVSDSKKPVIVCIKPLLSLQ----ETKEKMRKKY---------VACAQTIDNISRLFFPISFLIFNVVYWFAFKVML-KRNVHVGPI 465
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra2 (glycine receptor, alpha 2 [Source:ZFIN;Acc:ZDB-GENE-090407-1]) HSP 1 Score: 227.254 bits (578), Expect = 1.637e-69 Identity = 140/407 (34.40%), Postives = 224/407 (55.04%), Query Frame = 3
Query: 324 VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYY 1541
VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ +G VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W+ + + + +P+F + C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L R + +L + + L F+ + P N F + + N + + K A A + ++K V ID S+ FP F+++N FYW+ Y
Sbjct: 8 VTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWKQEGAVQVAEGLTLPQFVLKDEKDLVYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKELLRIRRRRQRNQIDL---TSLILICNIFTYFINSSV---PIFNMFKRV-EGNERALTKDSVSVKGVNATNAAPAPAPTQDAIKKKF---------VDRAKRIDTISRAAFPLAFLIFNIFYWIIY 391
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra1 (glycine receptor, alpha 1 [Source:NCBI gene;Acc:30676]) HSP 1 Score: 208.764 bits (530), Expect = 5.896e-64 Identity = 107/265 (40.38%), Postives = 167/265 (63.02%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI---VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHI-EKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVS 1061
GY RP+ T+ +VY+K + S++ M+Y ++LRQ+WID RL + H E + + + + + IW PDLFF N K Y H +TT N +LR+ NG VL++ ++T+ SC MDL+ FPMDTQ C M + S+GYT+ L F W EP+I+ + +P+F + + T C +L S+ TG ++CI A F L R++G YL Y+P+ LIV++SW++FW++++A PAR+ LG+ T+L + TQ+TG A+LP+V+
Sbjct: 16 GYDHRIRPNFGGPTVNVNCSVYIK--SFGSIEETTMDYQVTIFLRQKWIDPRLTYSHYPEPYLDLDQSNI-----QYIWRPDLFFDNEKSAYFHEVTTDNKMLRIFKNGLVLFTVRLTLTLSCPMDLRNFPMDTQMCYMFLESFGYTMADLSFHWDEEEPVIISKELVLPQFVLSSKIDTDSCDKLYSSGTGHFSCISARFVLHREMGFYLIQLYVPSALIVIISWVSFWINMEAAPARVALGITTVLTMTTQSTGARASLPKVT 273
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: glra4a (glycine receptor, alpha 4a [Source:ZFIN;Acc:ZDB-GENE-010410-3]) HSP 1 Score: 206.453 bits (524), Expect = 6.893e-61 Identity = 136/428 (31.78%), Postives = 213/428 (49.77%), Query Frame = 3
Query: 279 GYKSNERPS-ENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLV--SPLFKEKIWLPDLFFRNGKDGYVHS---MTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQEL-FKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYY 1541
GY S RP+ + +V + V V+ M+YS +++LRQ W D R+ ++ K YN + + F + +W PDLFF N K +T Y+ ++++ +C M L+ +PMD Q C++ + SYGYT + L F+W EP+ + P+F +C++ + G ++C+KATFFL R +G YL YIP+ L+V++SWL+FW++++A PAR+ LG+ T+L + TQ T +A LP+VSYIKAIDVW+ AC +FV AL+EFA +M +R+ D + EL +W + S+ Q H P+ + + K VF T N R +S + + ID S+ +FP FM++N FYW+ Y
Sbjct: 55 GYDSRMRPNVDGPPVVVNCSILVKGFGPVEEATMDYSINIFLRQTWNDPRIL--NVLKSIEYNTDFLDLGNSFVDSVWKPDLFFENEKSAAFQMYQLVTGFKYMYTFAMWITCFLCFRLSLVLACPMSLEVYPMDAQYCSIYLESYGYTTNDLIFQWNDTEPVSFGAGVSTPKFTLSNETFLGECTK--EYTYGTFSCVKATFFLDRDMGYYLIQVYIPSCLLVIISWLSFWLNVEAAPARVGLGITTILTVTTQMTSANAALPKVSYIKAIDVWMGACQVFVFSALLEFAAVNMATRRHGISPSHHDGDHGTKGELPIEWKRHRHANVSSVRRPQRH---RPERDCRSQ---------------GKPGVFHTNS--RRDENNATRVHVSDEEWRYQSLLHARRIDYISRVIFPTVFMIFNIFYWVIY 458
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002305.1 (pep scaffold:Pmarinus_7.0:GL478144:76380:93696:1 gene:ENSPMAG00000002075.1 transcript:ENSPMAT00000002305.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 192.586 bits (488), Expect = 6.685e-56 Identity = 129/438 (29.45%), Postives = 219/438 (50.00%), Query Frame = 3
Query: 282 YKSNERPS-ENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERL-----AWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRK---SKSELWQRDVQNIVHQELF---KWSKMALKKQQSINFLQMHLMGTPKTNSFTN------LAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYY 1541
Y RP+ +V + V + ++ M+Y +YL+Q WID R+ A + + F NN + + +W PDLFF N K H + ++ N + +S +++ +C M+L+ +P+DTQEC +++ S+GYT L F+W EP+++ + P+F + + DCS+ TG ++CI ATF+L R +G YL Y P+ L+V++SWL+FW+S+++ PAR++LG+ T+L + TQ T +A LP++SYIKA+DVW+ AC +FV AL+E + S+ + K+E RD +N +LF + + + +S+ +T S N ++Q +D A E +S+ + + +ID S+ LFP F+++ YW Y
Sbjct: 44 YDGRLRPNMYGSPVLVNCSVLVKSFGPIEENTMDYMMLIYLQQSWIDSRIESIYSAGHYQKDFLDLANNYI-----DTVWTPDLFFENEKSAAFHEIHCRFSIIVHATNNKTCFSLVLSLTLACPMNLEYYPLDTQECRINLESFGYTTQDLIFQWDENEPLVVATNLYTPKFKLSNHTELGDCSK--EYLTGTHSCINATFYLHRDMGYYLIQVYFPSCLLVIISWLSFWLSVESTPARVSLGITTILTVTTQMTSANAALPKMSYIKAMDVWMAACQVFVFAALLESTVVSVTKQHVVSGKAE--TRDQKNNNVWDLFFNPLYDVVGYNRSRSLG------RAAKRTTSVVNQPHGWFISQPTDSDGMARE-----------------------RSLVRSR----------QIDYISRVLFPLAFVIFLTIYWFSY 433
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO37555 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFG6]) HSP 1 Score: 197.593 bits (501), Expect = 1.209e-57 Identity = 132/439 (30.07%), Postives = 233/439 (53.08%), Query Frame = 3
Query: 243 SDREQIQNHIFKGYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCS-ELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSE-IDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
S+ + +++ +GY RP + VTV VL+I++++VI M+Y D +LRQ W D RL K R + +S +KIW+PD +F N K HS+TT N +L + P+G V Y+ ++T+K SC M+L+ FP D Q CN+DI SYGY+ D ++++W + + +I + Q N+ I+ S + G+++ + ATF +R+ G ++ Y P LIV++SW++F + ++ ARI LG+ ++L I T ++ ++P+VSY+KA+D ++I C LFV L+E+ I + +E +++D+ N +S ++K + H M N ++ + +H + + S E+L +P++ P V ID+E ID +++ LFP F+ +N Y++ + +
Sbjct: 4 SEMTSLLDNLIQGYDPRLRPDFGGDPVTVTVGFWVLSIDAINVIDMDYRMDFFLRQLWRDPRL------KHRFDDTLALSNTMLDKIWVPDTYFVNSKMSKFHSVTTINKMLSISPDGLVHYNSRVTVKASCAMNLRMFPKDVQNCNIDIESYGYSADNVQYQWENRSDNGIAVNKKIRDMPQ-YNLSDINVSRHFTMYVAGNWSGLTATFRFRRRSGYFIIHIYAPCALIVILSWISFCIPPESTAARIALGITSVLTITTILNMLNNSMPKVSYVKAVDWYLIGCFLFVFAVLLEYTFVLYIDNEEVTE-YKKDLVN--------YSSESVKHRSP-----AHAMNGSIPNGYSPAVFSEHGKKCGHNCHHAHHDVVLKREKHKSSYEQLGG--CRPRLKFPAV-IDTECIDEFARVLFPFIFIAFNVIYFIVFFFI 418
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO35410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK4]) HSP 1 Score: 186.037 bits (471), Expect = 1.587e-54 Identity = 104/324 (32.10%), Postives = 189/324 (58.33%), Query Frame = 3
Query: 195 ICFFF---MSTTSLGTSMNSDREQIQNHIFKGYKSNERP-SENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWR----SWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIAS 1142
+CF F ST S + + ++ +GY RP S+ + +V V M V I ++ + M+++ D+YLRQ W DERL E +S ++IW+P +F K Y H +TT NYLL+++P+G + YS ++T+ SC++DL+ FP DTQ C++ + SYGY + + W + + + +++P+F + ++++ + G+++ + A F ++R++G +L TYIP+ +IV++SW++FW+ + PAR+ LG+ T+L + T + ANLP+VSY+KAID +++ C++FV G+++E+ +
Sbjct: 1 MCFHFSGQFSTKSTPAGKYWNSTLVLKNLLEGYDRRIRPGSKGEPVVVYVDMYVSNIWAMQEMNMDFTIDIYLRQYWRDERL---QFETQTPGAMLTLSSDINKQIWVPSTYFLATKKAYFHDVTTDNYLLQVKPDGSLFYSIRLTITTSCRLDLRDFPHDTQSCSLSLESYGYQSTDVLYVWNERLDNTSAIYIHDDLELPQFEV---LGVSRSAKMNKYNIGNHSSLVANFRMKRRIGYFLIDTYIPSTIIVIISWISFWIDPETAPARVALGITTVLTMTTLISSARANLPKVSYVKAIDWYLLLCLIFVFGSILEYTCVT 318
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO47783 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL25]) HSP 1 Score: 185.652 bits (470), Expect = 2.682e-54 Identity = 108/312 (34.62%), Postives = 182/312 (58.33%), Query Frame = 3
Query: 255 QIQNHIFKGYKSNERP--SENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSST-STGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQR 1181
+ N +F GY RP + +VTV +L+I++++VI M++S D++LRQEW D+RL DH ++ +S +KIWLPD +F N KD H++TT N ++ L P G V Y+ +++++ C M+L+ FPMDTQ C + SYGY+ + F W I + +P++ N+K + S + G+++ +KATF +R ++ Y P+ +IV++SW+ F + D PARITLG+ ++L I+T +S + +V+Y+K ID ++I C LFV +LIE++ +++ + K +QR
Sbjct: 3 DVLNDLFSGYDRRVRPHYEDGHPVVVTVGFTLLSIDTINVIDMDFSMDMFLRQEWYDQRL--DH----KTNETVFLSNHVMDKIWLPDSYFVNAKDAKFHTVTTDNKMIMLSPGGRVQYNARVSVRLYCDMELRDFPMDTQYCPVVFESYGYSDRHITFVWELGMNTIPERLKILPQY----NLKEVALSTTYNVYVVGNWSGVKATFAFERTYSYFIYHVYAPSAIIVVISWIGFVLPRDKPPARITLGVTSVLTIVTVLNMLSNTVAKVNYVKRIDEYLIGCFLFVFCSLIEYSFVLLLAYRMKK--YQR 302
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO30047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1W8]) HSP 1 Score: 184.111 bits (466), Expect = 5.060e-54 Identity = 107/308 (34.74%), Postives = 183/308 (59.42%), Query Frame = 3
Query: 255 QIQNHIFKGYKSNERPSEN---KQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRW--RSWEPMILPP--VMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISR 1154
+I + I K ++R N IVTV VL+I++++V+ M+Y+ D++LRQ W+DERL+ D N + +S +KIWLPD +F N K G H +T N ++ +QP+G+V Y+ ++T++ SC M+L+ FPMDTQ C + + SYGY+ D + F+W + + P + +P++ N SEL G+++ IKA F +R ++ Y P LIV+VSW++F + + PARITLG+ ++L ++T ++ ++P+V+Y+K ID ++I C LFV L+E+++ +++
Sbjct: 3 RILDSILTAEKYDKRLRPNYGAGPVIVTVGFWVLSIDTINVVDMDYTLDIFLRQSWVDERLSHD-------LNTTMFLSNTVMDKIWLPDSYFVNAKQGSFHKVTKDNMMVMIQPDGQVQYNARVTIRASCPMNLRKFPMDTQHCPLTLESYGYSSDHIVFKWEIEDGDGLGFVPESLKMLPQYKLAPNEPR---SELCFVIPGNWSGIKALFTFERMYSYFVIHVYGPCALIVVVSWVSFLLPKEQAPARITLGVTSVLTVVTILNMLNNSMPKVNYVKTIDKYLIGCFLFVFATLVEYSLVLWLTK 300
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Match: EDO34692 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNK5]) HSP 1 Score: 180.644 bits (457), Expect = 6.050e-53 Identity = 102/266 (38.35%), Postives = 165/266 (62.03%), Query Frame = 3
Query: 381 YSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFK---EKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRS----WEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRK 1157
++ D+YLRQ W D RL +D + N V L + ++IW+P +F N K Y H +TT NYLL ++PNG+V YS ++T+ +C++ LQ FP D Q C M + SYGY + +RW S + + + +++P+F + TNVK + + + + G ++ + A F R+LG Y+ TYIP++L V +SW +FW+S D+ PAR+ LG+ T+L ++T + A LP+VSY KAID +++ C+++V GAL+E+AI + + K
Sbjct: 2 FTIDMYLRQYWRDPRLIFDPVPV-----NTDVLTLNRQTIDEIWIPSTYFFNAKKAYFHDVTTENYLLMIKPNGDVFYSVRLTITMACKLTLQMFPHDVQVCEMMLESYGYQATDVYYRWNSRNSTGDVVYISEDLEMPQF-KITNVKLEERTNIY--NIGPHSALIAKFTFHRRLGYYMIQTYIPSMLTVTISWFSFWISPDSPPARVGLGITTVLTMITISNSARAPLPKVSYTKAIDWFLLMCLVYVFGALMEYAIVNFYACK 259
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: ENSORLT00000025211.2 (glycine receptor subunit alpha-3 [Source:NCBI gene;Acc:101174559]) HSP 1 Score: 244.202 bits (622), Expect = 1.248e-74 Identity = 144/430 (33.49%), Postives = 238/430 (55.35%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMH----LMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + V+ + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K + H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F+W+ P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G +LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ H+EL ++ + K ++ + ++ + TP + + + N+ +AN + A E++RK + +ID S+ FP F+ +N FYW+ Y IL
Sbjct: 48 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYAEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFQWQENGPVQVAEGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ--------------HKELLRFRRHKSKTKEEVGESKLTSTAVMTSTPSISKDSKASVNNAVAPAANTTQNA-----PAAGGGGRSTEEMRKLF---------IDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 442
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra4a (glycine receptor subunit alpha-4-like [Source:NCBI gene;Acc:101156095]) HSP 1 Score: 243.047 bits (619), Expect = 4.333e-74 Identity = 154/440 (35.00%), Postives = 236/440 (53.64%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKS--ELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNS--FTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIEMGL 1580
GY + RP+ + VT + + + S+ M+Y +V+LRQ W D RLA+ +N+L + P + IW PDLFF N K H +TT N LLR+ +G VLYS ++T+ SC MDL+ FPMD Q C M + S+GYT++ L F W S P+ + + +P+F C++ +TG +TCI+ F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ K L ++ Q + +EL + S+ + + G P + F+ M D EVF S+ V ID S+ +FP F+++N FYWL Y +L R +I L
Sbjct: 56 GYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQNWNDPRLAYSEYP-----DNSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQDGSVLYSIRLTLILSCPMDLKNFPMDIQTCTMQLESFGYTMNDLIFEWLSDNPVQVADDLTLPQFVLKEEKDLGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFIRLRKKQRQQRIEEELVRESRGFYFRGYGLGHCLQTKDGAPLEGATVFSPPPPMTMYDG---------EVF-----------------------SKRFVDRAKRIDTISRAVFPLSFLIFNIFYWLTYKVL-RHEDIHANL 455
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra4b (glycine receptor subunit alpha-2 [Source:NCBI gene;Acc:101174852]) HSP 1 Score: 241.891 bits (616), Expect = 2.140e-73 Identity = 151/443 (34.09%), Postives = 240/443 (54.18%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVS--PLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLE----ASPNEKLRKSISKPQVSEPP------------VQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +V+LRQ+W D RLA ++ Y ++ + P + IW PDLFF N K H +TT N LLR+ NG VLYS ++T+ SC MDL+ FPMD+Q C M + S+GYT++ L F W + + + +P+F C++ +T G +TCI+ F+L+RQ+G YL YIP++L V++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + +SR+ H+E F+ K LK+QQ + N+ N A + + + + E+ LL+ A E+ + + P ++ P V+ ID S+ LFP F+++N YWL Y +L
Sbjct: 52 GYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLA------YKEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDSQMCTMQLESFGYTMNDLIFEWLDVGAVQVADDLMLPQFVLKEEKGLGYCTKYYNT--GKFTCIEVKFYLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ--------------HKEFFRMRK-KLKEQQRLRTGSAD-SKVKGNNTPGNSAAQGNVNQRCSACAREEELAQQGYLLQSFGLALSTERGPEMDATPVFADLPPGLGFYEIRRRFVERAKRIDTISRALFPMTFLVFNVLYWLTYKVL 470
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557]) HSP 1 Score: 234.958 bits (598), Expect = 2.762e-71 Identity = 144/426 (33.80%), Postives = 231/426 (54.23%), Query Frame = 3
Query: 279 GYKSNERPSENKQTI-VTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
GY + RP+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + I+R+ K L R + + ++ + + MG + +A + +N+ T+ E S E + I + + ID S+ FP F+++N FYW+ Y I+
Sbjct: 40 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFRRRRRHMKEDETGDGRFGFPG---------YGMGPACLQAKDGMAIKGNNNNAP-----------TSAAPEKSIEEMKKLFIGRAK----------RIDTVSRVAFPLVFLIFNIFYWITYKII 428
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Match: glra1 (glycine receptor alpha 1 [Source:NCBI gene;Acc:101173557]) HSP 1 Score: 233.802 bits (595), Expect = 9.850e-71 Identity = 143/426 (33.57%), Postives = 229/426 (53.76%), Query Frame = 3
Query: 276 KGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNL-VSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLIL 1550
KG K+ + VT + + + S+ M+Y +++LRQ+W D RLA+ +++L + P + IW PDLFF N K H +TT N LLR+ NG VLYS +IT+ +C MDL+ FPMD Q C M + S+GYT++ L F W + + + +P+F C++ +TG +TCI+A F L+RQ+G YL YIP++LIV++SW++FW+++DA PAR+ LG+ T+L + TQ++G A+LP+VSY+KAID+W+ C+LFV AL+E+A + I+R+ K L R + + ++ + + MG + +A + +N+ T+ E S E + I + + ID S+ FP F+++N FYW+ Y I+
Sbjct: 53 KGSKNEATHKKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYP-----DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIARQHKELLRFRRRRRHMKEDETGDGRFGFPG---------YGMGPACLQAKDGMAIKGNNNNAP-----------TSAAPEKSIEEMKKLFIGRAK----------RIDTVSRVAFPLVFLIFNIFYWITYKII 441
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000037124.1 (SMESG000037124.1) HSP 1 Score: 924.85 bits (2389), Expect = 0.000e+0 Identity = 459/460 (99.78%), Postives = 459/460 (99.78%), Query Frame = 3
Query: 210 MSTTSLGTSMNSDREQIQNHIFKGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIEMGLINN 1589
MSTT LGTSMNSDREQIQNHIFKGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARITLGLLTLLGILTQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIEMGLINN
Sbjct: 1 MSTTFLGTSMNSDREQIQNHIFKGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARITLGLLTLLGILTQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRNIEMGLINN 460
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000041885.1 (SMESG000041885.1) HSP 1 Score: 524.628 bits (1350), Expect = 0.000e+0 Identity = 267/441 (60.54%), Postives = 333/441 (75.51%), Query Frame = 3
Query: 237 MNSDREQIQNHIF--KGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILV 1553
M R+ I I K YK +ERPSE QT V VYMKVLAINSV V KMEYSTDVYLRQEW D RL W+++E+FRS+NNN+VSP K+ +WLPDLFFRNGK+GYVH MT PNYL+RL+PNG +LYSQKITM+FSC+M+LQTFPMD+QEC MDIGSYGYTLD+LKF WR +P+++ +QI EFN P V TIDC+ SSTSTG YTC+KA F LQRQLGSYL ST++P++LIVMVSWLNFW+++D+VPAR+TLGL+TLLG+LTQATG+S+ LPRVSYIKAIDVW+IACI+FVIGAL+E+ +AS+++RK KS W++DV+ IV EL +W A ++QQ F +L + N+ D + EF +LE L L+A +K K+ P + DS+ID YS+FLFPA F+LYNCFYWLYYL+LV
Sbjct: 28 MAQQRDLIMERIVDKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARVTLGLVTLLGMLTQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCS-ACQRQQ-----------------FFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTT--------PTE-DSDIDSYSRFLFPACFLLYNCFYWLYYLVLV 441
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000061905.1 (SMESG000061905.1) HSP 1 Score: 499.204 bits (1284), Expect = 8.384e-174 Identity = 279/450 (62.00%), Postives = 339/450 (75.33%), Query Frame = 3
Query: 213 STTSLGTSMNSDREQIQNHIFKGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFL---TAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILV 1553
++T+ + N RE I +F+ Y +ERPSE KQT V VYM+VLAINSVDV+KMEYSTDV LRQEW+D+RL W + SYN ++ SP KEK+WLPDLFFRNGK GYVHSMT PNYL+RL NG +LYSQKITM+FSCQM+L TFPMD+QEC MDIGSYGYTLDQLKF WR EP+I+ +QIPEFN T+ T DCS+ + TSTG+YTC+KA+F L+RQLGSYLASTYIPNVLIVMVSWLNFWVS++A+PARITLGLLTLLGILTQATGMS +LPRVSYIKAID+WIIACI+FVIGALIEFA+ASMI+R+ KSE WQ+ V+ IV QEL +W + ++Q + +S + Q + + + LE+ L T Q + P +K+ + SKPQ S +DSEID YS+FLFPA F+LYNCFYWLYYL+LV
Sbjct: 37 NSTTYFSENNVTREDILKIVFENYNLHERPSEVKQTEVVVYMRVLAINSVDVLKMEYSTDVLLRQEWLDDRLTWHRHPRLASYNKSISSPALKEKVWLPDLFFRNGKKGYVHSMTLPNYLMRLNSNGMILYSQKITMRFSCQMNLSTFPMDSQECIMDIGSYGYTLDQLKFLWREKEPIIIASNIQIPEFNPSTDPYTFDCSKEAGTSTGNYTCLKASFHLRRQLGSYLASTYIPNVLIVMVSWLNFWVSVEAIPARITLGLLTLLGILTQATGMSNSLPRVSYIKAIDIWIIACIIFVIGALIEFAMASMIARRRKSEDWQKQVREIVRQELARWCAVCQQQQLV----------QIQNSSLIDRTQFETPIGTED-----LEILLCPDTVQKWKKKPVQKVNR--SKPQKS-----VDSEIDCYSRFLFPACFVLYNCFYWLYYLVLV 464
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000008993.1 (SMESG000008993.1) HSP 1 Score: 490.345 bits (1261), Expect = 4.112e-170 Identity = 257/475 (54.11%), Postives = 344/475 (72.42%), Query Frame = 3
Query: 189 FSICFFFMSTT-SLGTSMNSDREQIQNHIFKG--YKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQE--LFKWSKMALKKQQSI---------NFLQMHLMGT-----PKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVR 1556
F++ STT + + S +E+I+N + YK ERP EN T+V +Y+K+LAI+SVDV +M+YSTDVYLRQ WID RL W+H+E+F+ YN+N+VSP K++IWLPDLFFRNGK GY+H+MTTPNYL+RLQPNGEVLYSQK+TM FSCQM+LQ FPMDTQ C ++IGSYGYTL++LKF WR+++ + + ++IPEF+ P ++TIDC++ S+TSTG+YTC+KA L RQLGSYLASTY+P++LI+MVSW+NFWVSIDAVPARITLGLL+LLGI+ A MS+ LPRVSYIKAIDVW+IACI+FVI AL+EFAIA+ + +++ S+ WQ DV +++ +E L S +K SI N ++ +MG P N + + S + S NE L +L E N+ R ++ KP ++ +DS ID YS+FLFPA F+LYNCFYWLYY++L+R
Sbjct: 16 FTVFILVNSTTCDISSKYLSTQERIRNKLLDKIVYKKQERPDENNTTLVMIYIKILAIDSVDVRQMQYSTDVYLRQAWIDSRLRWEHLEEFKHYNSNIVSPSLKDEIWLPDLFFRNGKKGYIHNMTTPNYLMRLQPNGEVLYSQKLTMVFSCQMELQAFPMDTQNCEINIGSYGYTLEELKFYWRTFDTIAVQKELKIPEFDTPDIIETIDCTQDSATSTGNYTCLKAIITLNRQLGSYLASTYVPSILIIMVSWMNFWVSIDAVPARITLGLLSLLGIVNMAISMSSTLPRVSYIKAIDVWLIACIIFVIAALVEFAIATSVLKRNTSKSWQSDVCSLIREEINLMHTSFSMIKSMNSISKEKKSNNNNSNRVGIMGATGTAKPIPNLPPGIDMLFSNNPSQNE-------VLLKELDER--NKMSRFTMKKPNNTKSKSSVDSTIDNYSRFLFPACFLLYNCFYWLYYIVLIR 481
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Match: SMESG000032691.1 (SMESG000032691.1) HSP 1 Score: 488.034 bits (1255), Expect = 9.581e-170 Identity = 260/456 (57.02%), Postives = 339/456 (74.34%), Query Frame = 3
Query: 201 FFFMSTTSLGTSMNS----DREQIQNHIFKGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARXXXXXXXXXXXXXQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQI-DSEIDGYSQFLFPAFFMLYNCFYWLYYLILV 1553
F F+ +G + S RE+I + I + Y NERP E+ QT V V+MKVLAINSV+V MEYSTD+YLRQ W+D RL WD++ +F+ +N++LVSP K+++WLPDLFFRNGK+GYVH MT PNYL+RL PNGEVLYSQKITM+FSCQMDLQT+PMDTQ C M+IGSYGYTLDQLKF W PM L +QIPEFN PT V+T DC+ S+T TG Y+C+KA F L+RQLGSYL ST+IPN LIV+VSWLNFWVS++AVPARITLGLLTLLGILTQA+G+S NLPRVSYIKAIDVW+IACI+FVIGAL+EFA+AS ++++ K W+ +V++IV QEL +W+ +A+ +Q++ H M T + + L EF +L++ LTAQ + + N ++S + + + +I +S+ID YS++LFP+ F+ YN YW+YYLI+V
Sbjct: 11 FIFLLAIHVGCNSCSVAGITRERIMDKILQNYSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDARLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARITLGLLTLLGILTQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWN-LAINRQKT------HHMQTSQILNRNEL-----------EFCEELDILLTAQ--QYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIV 446 The following BLAST results are available for this feature:
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Glycine receptor subunit alpha-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30023116 ID=SMED30023116|Name=Glycine receptor subunit alpha-3|organism=Schmidtea mediterranea sexual|type=transcript|length=1602bpback to top protein sequence of SMED30023116-orf-1 >SMED30023116-orf-1 ID=SMED30023116-orf-1|Name=SMED30023116-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=472bp MIKCFSICFFFMSTTSLGTSMNSDREQIQNHIFKGYKSNERPSENKQTIVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
