Filamin
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30023110 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of Filamin vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755]) HSP 1 Score: 1339.71 bits (3466), Expect = 0.000e+0 Identity = 859/2302 (37.32%), Postives = 1250/2302 (54.30%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP----YKESKIKAFGPGL--TGGIVSKPAFFEVETN--GETGALGFSIKGPSEA-KIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPST-----VKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS----VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQET--NNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVV-----------DFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX---------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGST-----QKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 ++ +V A GPGLE GN P F + T AG G++ + V +P+G K E+ Y C Y P G + + I FA IP SPF V V A +P+ ASG G++P G + T F V T AG G + + KG ++ VK K + + EY G +S+ + + G I SPF V V + + ++ A G G+ G V A+F V + + LG + GP ++ + + C + Y P+ PG Y V I + I SP+ + P Y ++A+GPGL +G IV+ A F V+ G+ F+ G + I + DG+ +Y P ++ + ++ NIP SPY I + P KV +GPG+ SG+ N+P F V+ AG A + + I N + T++ +Y P G++T+ V + + IP SPF+V V + +A+ +K GPG+ +A + T+F V K AG + + + + ++D+ ++ DN D + T+KYTP G + + + IP+SPF V + + D K K+N L N +G+ EF + T G + + ++ + SP+ VP + A F P G + V V G+P+ SPY V A+ D K + P E L+ A++ ID K + + P E + ++ N + S ++ P + Y V E KA++ P V A G GL G +D +E P LG+ + +A++ +N DGT +V Y+P G Y + + Y E + P V + P D +++ +GPG+ VF+++ + FTV+++P+ G +KA I NP + C V +N DGTY Y+P G H +++TYD VP+ SP+ V V +G PSR++A GPGL+E T +P FTV GAG GGLG+++EGP++++I C DNKDG+CS +Y+P PG YDV+I + HIPGSPF VP+ D+VD SKVK GPGL +G R FTVD+SKAG APL+V V+ V+P ++ G VTY P G + V Y + ++P SPF VL + + KV +G G+ + + +P F I+ RDAGE L + +T + V ++ DGT+ Y D G Y + V YG ++P SP+ + +C GP I + V G+ V V+ + AG G ++ + P G + G + Y K G Y + + F +IPN +++ T T + P+ Y V D P + V+ PS + P +++N DGT+TV+Y P+E GLHE+ + Y G I SP +FYV+ SG V+AYGPGL YG + A FTIVT+DAG GGL LA+EGPSKAEI CIDNK+GTC V+YLP PGDY I +K+ DKHI GSPFTAKI + ++ SQ+ +G+ +D L ISETD+++L A + +P+GR+E C LKRL N ++GISF P+EVGEHLV++ ++G H+ NSP I V ++EIG+A R K+YG GL++G E F+VDTR+AGYGG+SL++EGPSKV+I+ D DGTC V+Y PT PG YI++ K+AD +VPGSPF V I G + E I R A V+ +G++C+LNL IP N + +A V SPSG EI+ + N +RF+P+E+GVHTVSVK +HVTGSPFQFTVGPL +GG HKV G G+ERG A +F+I+TREAGAG LSIA+EGPSKAEI F D+K+GSCGV+Y EPG+Y SIKFNDEH+P SP+++ PV + +D+R +++ +LQ+ G + A+F I +G G I A V SPS + +S+++ ++Y+V F+P ENG+H + V N S + GSPF+V V V+ G G+ G TG +EFF++T+ AG G L+VTI+GPSKV+++CQE GY Y P APG+Y IS+KYGG NHI+GSPF ++G S S ET S L ++V S T K S V +G GL A +G+++ F+VD AG ++L +GV GP PCEEV++KH+GN ++ V Y V+E+G ++L V+WG +PGSPF + VP Sbjct: 353 DASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEAC-NPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQK--DFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPE---AGMQKVRAWGPGLH--GGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSC--DVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSH---PQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDII--DNYDYSHTVKYTPTQQGNMQVL-VTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG--PCE-AKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAV-------DTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL-GSGVRARVLQSFTVDSSKAGLAPLEVRVLG-PRGLVEPVNVVDNGD-GTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYG---VPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPN-----------SPFTVMATDGEVTAVEEAPVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYP-NSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISG--EGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLV------------PVIAPS---DDARRLTVMSLQESGLKVNQPASFAIRLNG-AKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 2591 HSP 2 Score: 1066.99 bits (2758), Expect = 0.000e+0 Identity = 848/2595 (32.68%), Postives = 1244/2595 (47.94%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYK-ESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS------VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNT---TPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE--EGITKQPQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFT--PSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE--YSVVDFKFPVGPVFDY-------VRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVD----STIPSGQVT--AYGP-----GLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVG---------TTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAV-----NIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDAN--QFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRX---XXXXXXXXXXXIHHGHTG-RINE--FFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWG--NHDVPGSPFEIVV 7621 + E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS +R H+RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGL+WTLILHYSI+MP+WE ++ D K +PKQRLLGWI +K+P+ P+ NF +W DG A+GALVD+CAPGLCP+W WDP++ + NA+EA+ A++ L V +I P E+I+P VDE ++MTYLSQFP A+L APL PK N + RAYG G+E GN + PA FTVDT +AG+G++ + V +P+G KE ++ +K YS Y+P + G +++ + FA I SPF+V+V A GD SKVTA GPG+E VGN + T+F+++TA AG G + + D +G K++V+ + + + Y + G H V +FFAG I SPF V V + N +A + A+GRG+QP+GVR+R+ +F+V T+ AG +LGV + GP E + K +Y Y P PG Y + I +G + I SPF V V P K++A+GPGL GGIV + A F VE+ G E G+LGF+I+GPS+AKI+ D DGS +V YWP PGEYAVHI+CDDE+I SPYMA I T ++P V AYGPGL SG N A+F V+ K+AG + +K D GQ I +Q+++ DGTY+C YTP KHT+ V +G VNIP SP++VN+ + + +KV+GPG+ER+ K N T+F VDC AG GD+ + VL E DV N + TF YTI++ F+ EIP SPF+V ++ +D K K + G+ F + T G K + SP L +N +TPT G V V G+PI SP+ V ++ + E + ++ +D + + L+P R V P R N F P EE +Y V T + E P V A+G GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP +PG Y VN+L+ + HI SPF I D +KV A GPGL V + + G G + + ++ ++ NN DGTY+ +Y P G + + + Y G V P V V D SRI+ +GPG+E + + FTVD L G + I P+ A +CF DN DGT V+Y P + G + V + +++ IP SPF V + + S+V+ GPGL+ FT P+ FTV AG L + V + + + G YIP G+ ++ + Y +PGSPF V + +P KV + G G+ G + +V FT+++ AG + LE+ V GP ++V ++GDGT T Y G Y V V Y ++ +P SPF V V + GP L+ VP V ++ ++AG+G+L+ + G + + + G V+Y+P K G Y + + + ++IP R A Q T + SK + S V VG V D V V P + +I N DGT + Y ++ G + + V + G I SPF + + VT AY P GL + D+ F + G ++ V PS A + +DNK+GT V Y P G + + IK+M HI SP + P S G T+ + + L+ + P+ E SC + +G +++ P G++ + V + +HIP SPF + ++ S+VKL F++D L+ SI+ PS + C +NH G +++ P E G +++++K ++V SP ++ IG + + R L E+S ++ GY + +V PS E L D + + P GV+ VS K + HV GSPF + G K I + +A + + E + +S + PS +AEI K+ C V + E G + S+K+ +HV GSPF + P + + + G A F I G +S V PS E + N V ++ E G + V + N+ IP SP+ V + + +G ++N+ F N G + + PS C +E Y ++P+ G +TI +K+ G +H++GSPF V + N P V G GL+ G ++EF ++ AG L V + GP + C+E ++V Y G +L+ V++G NH V GSPF+ V Sbjct: 3 VTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWE----DEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQV-GEACNPNACR--ASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGK-APLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTF-TVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAG-KAPLNVQFNSPLPGDAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQG-KLDVTILSP-SRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADI-------EMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEA-----GPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLK----EAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKIN----CRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL----GSGVRARVLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQ--------------TGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVTEEAYVPVSDMNGLGFKPFDLVIPFAVRK-----GEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYV-NYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNK--DGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDS-RRCSQVKL----------GSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIG---ISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDF----IVDTRDAGYG--GISLAVEGPSKVDIQTE--DLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKIS---GEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEI-VPMGKNSHC-VRFVPQEMGVHTVSVKYRGQHVTGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNG-SHVVGSPFKVRVGEPGQAGN--------------------------PALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQET------PEGYKVMYTPMAPGNYLISVKYGGPNHIV-GSPFKAKV 2460
BLAST of Filamin vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755]) HSP 1 Score: 1339.32 bits (3465), Expect = 0.000e+0 Identity = 860/2303 (37.34%), Postives = 1251/2303 (54.32%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP----YKESKIKAFGPGL--TGGIVSKPAFFEVETN--GETGALGFSIKGPSEA-KIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPST-----VKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS----VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQET--NNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSV------------VDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX---------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGST-----QKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 ++ +V A GPGLE GN P F + T AG G++ + V +P+G K E+ Y C Y P G + + I FA IP SPF V V A +P+ ASG G++P G + T F V T AG G + + KG ++ VK K + + EY G +S+ + + G I SPF V V + + ++ A G G+ G V A+F V + + LG + GP ++ + + C + Y P+ PG Y V I + I SP+ + P Y ++A+GPGL +G IV+ A F V+ G+ F+ G + I + DG+ +Y P ++ + ++ NIP SPY I + P KV +GPG+ SG+ N+P F V+ AG A + + I N + T++ +Y P G++T+ V + + IP SPF+V V + +A+ +K GPG+ +A + T+F V K AG + + + + ++D+ ++ DN D + T+KYTP G + + + IP+SPF V + + D K K+N L N +G+ EF + T G + + ++ + SP+ VP + A F P G + V V G+P+ SPY V A+ D K + P E L+ A++ ID K + + P E + ++ N + S ++ P + Y V E KA++ P V A G GL G +D +E P LG+ + +A++ +N DGT +V Y+P G Y + + Y E + P V + P D +++ +GPG+ VF+++ + FTV+++P+ G +KA I NP + C V +N DGTY Y+P G H +++TYD VP+ SP+ V V +G PSR++A GPGL+E T +P FTV GAG GGLG+++EGP++++I C DNKDG+CS +Y+P PG YDV+I + HIPGSPF VP+ D+VD SKVK GPGL +G R FTVD+SKAG APL+V V+ V+P ++ G VTY P G + V Y + ++P SPF VL + + KV +G G+ + + +P F I+ RDAGE L + +T + V ++ DGT+ Y D G Y + V YG ++P SP+ + +C GP I + V G+ V V+ + AG G ++ + P G + G + Y K G Y + + F +IPN A E ++E + +P + E V D P + V+ PS + P +++N DGT+TV+Y P+E GLHE+ + Y G I SP +FYV+ SG V+AYGPGL YG + A FTIVT+DAG GGL LA+EGPSKAEI CIDNK+GTC V+YLP PGDY I +K+ DKHI GSPFTAKI + ++ SQ+ +G+ +D L ISETD+++L A + +P+GR+E C LKRL N ++GISF P+EVGEHLV++ ++G H+ NSP I V ++EIG+A R K+YG GL++G E F+VDTR+AGYGG+SL++EGPSKV+I+ D DGTC V+Y PT PG YI++ K+AD +VPGSPF V I G + E I R A V+ +G++C+LNL IP N + +A V SPSG EI+ + N +RF+P+E+GVHTVSVK +HVTGSPFQFTVGPL +GG HKV G G+ERG A +F+I+TREAGAG LSIA+EGPSKAEI F D+K+GSCGV+Y EPG+Y SIKFNDEH+P SP+++ PV + +D+R +++ +LQ+ G + A+F I +G G I A V SPS + +S+++ ++Y+V F+P ENG+H + V N S + GSPF+V V V+ G G+ G TG +EFF++T+ AG G L+VTI+GPSKV+++CQE GY Y P APG+Y IS+KYGG NHI+GSPF ++G S S ET S L ++V S T K S V +G GL A +G+++ F+VD AG ++L +GV GP PCEEV++KH+GN ++ V Y V+E+G ++L V+WG +PGSPF + VP Sbjct: 353 DASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEAC-NPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQK--DFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPE---AGMQKVRAWGPGLH--GGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSC--DVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSH---PQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDII--DNYDYSHTVKYTPTQQGNMQVL-VTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG--PCE-AKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAV-------DTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL-GSGVRARVLQSFTVDSSKAGLAPLEVRVLG-PRGLVEPVNVVDNGD-GTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYG---VPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATD-GEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYP-NSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISG--EGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLV------------PVIAPS---DDARRLTVMSLQESGLKVNQPASFAIRLNG-AKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 2602 HSP 2 Score: 1066.22 bits (2756), Expect = 0.000e+0 Identity = 850/2604 (32.64%), Postives = 1244/2604 (47.77%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYK-ESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS------VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPI---GQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE--EGITKQPQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFT--PSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE--YSVVDFKFPVGPVFDY-------VRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVD----STIPSGQVTAYGPGLSYGRP-----------DMHAH----FTIVTKDA-GAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVG---------TTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAV-----NIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDAN--QFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRX---XXXXXXXXXXXIHHGHTG-RINE--FFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWG--NHDVPGSPFEIVV 7621 + E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS +R H+RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGL+WTLILHYSI+MP+WE ++ D K +PKQRLLGWI +K+P+ P+ NF +W DG A+GALVD+CAPGLCP+W WDP++ + NA+EA+ A++ L V +I P E+I+P VDE ++MTYLSQFP A+L APL PK N + RAYG G+E GN + PA FTVDT +AG+G++ + V +P+G KE ++ +K YS Y+P + G +++ + FA I SPF+V+V A GD SKVTA GPG+E VGN + T+F+++TA AG G + + D +G K++V+ + + + Y + G H V +FFAG I SPF V V + N +A A+GRG+QP+GVR+R+ +F+V T+ AG +LGV + GP E + K +Y Y P PG Y + I +G + I SPF V V P K++A+GPGL GGIV + A F VE+ G E G+LGF+I+GPS+AKI+ D DGS +V YWP PGEYAVHI+CDDE+I SPYMA I T ++P V AYGPGL SG N A+F V+ K+AG + +K D GQ I +Q+++ DGTY+C YTP KHT+ V +G VNIP SP++VN+ + + +KV+GPG+ER+ K N T+F VDC AG GD+ + VL E DV N + TF YTI++ F+ EIP SPF+V ++ +D K K + G+ F + T G K + SP L +N +TPT G V V G+PI SP+ V ++ + E + ++ +D + + L+P R V P R N F P EE +Y V T + E P V A+G GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP +PG Y VN+L+ + HI SPF I D +KV A GPGL V + + G G + + ++ ++ NN DGTY+ +Y P G + + + Y G V P V V D SRI+ +GPG+E + + FTVD L G + I P+ A +CF DN DGT V+Y P + G + V + +++ IP SPF V + + S+V+ GPGL+ FT P+ FTV AG L + V + + + G YIP G+ ++ + Y +PGSPF V + +P KV + G G+ G + +V FT+++ AG + LE+ V GP ++V ++GDGT T Y G Y V V Y ++ +P SPF V V + GP L+ VP V ++ ++AG+G+L+ + G + + + G V+Y+P K G Y + + + ++IP R A Q T + SK + S V VG V D V V P + +I N DGT + Y ++ G + + V + G I SPF + + V A PG RP DM+ F +V A G ++ V PS A + +DNK+GT V Y P G + + IK+M HI SP + P S G T+ + + L+ + P+ E SC + +G +++ P G++ + V + +HIP SPF + ++ S+VKL F++D L+ SI+ PS + C +NH G +++ P E G +++++K ++V SP ++ IG + + R L E+S ++ GY + +V PS E L D + + P GV+ VS K + HV GSPF + G K I + +A + + E + +S + PS +AEI K+ C V + E G + S+K+ +HV GSPF + P + + + G A F I G +S V PS E + N V ++ E G + V + N+ IP SP+ V + + +G ++N+ F N G + + PS C +E Y ++P+ G +TI +K+ G +H++GSPF V + N P V G GL+ G ++EF ++ AG L V + GP + C+E ++V Y G +L+ V++G NH V GSPF+ V Sbjct: 3 VTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWE----DEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQV-GEACNPNA--CRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGK-APLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTF-TVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAG-KAPLNVQFNSPLPGDAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQG-KLDVTILSP-SRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADI-------EMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEA-----GPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLK----EAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKIN----CRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL----GSGVRARVLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQ--------------TGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGF---RPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYV-NYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNK--DGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDS-RRCSQVKL----------GSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIG---ISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDF----IVDTRDAGYG--GISLAVEGPSKVDIQTE--DLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKIS---GEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEI-VPMGKNSHC-VRFVPQEMGVHTVSVKYRGQHVTGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNG-SHVVGSPFKVRVGEPGQAGN--------------------------PALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQET------PEGYKVMYTPMAPGNYLISVKYGGPNHIV-GSPFKAKV 2471
BLAST of Filamin vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755]) HSP 1 Score: 1337.01 bits (3459), Expect = 0.000e+0 Identity = 858/2294 (37.40%), Postives = 1246/2294 (54.32%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP----YKESKIKAFGPGL--TGGIVSKPAFFEVETN--GETGALGFSIKGPSEA-KIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPST-----VKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS----VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQET--NNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE---YSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX---------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGST-----QKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 ++ +V A GPGLE GN P F + T AG G++ + V +P+G K E+ Y C Y P G + + I FA IP SPF V V A +P+ ASG G++P G + T F V T AG G + + KG ++ VK K + + EY G +S+ + + G I SPF V V + + ++ A G G+ G V A+F V + + LG + GP ++ + + C + Y P+ PG Y V I + I SP+ + P Y ++A+GPGL +G IV+ A F V+ G+ F+ G + I + DG+ +Y P ++ + ++ NIP SPY I + P KV +GPG+ SG+ N+P F V+ AG A + + I N + T++ +Y P G++T+ V + + IP SPF+V V + +A+ +K GPG+ +A + T+F V K AG + + + + ++D+ ++ DN D + T+KYTP G + + + IP+SPF V + + D K K+N L N +G+ EF + T G + + ++ + SP+ VP + A F P G + V V G+P+ SPY V A+ D K + P E L+ A++ ID K + + P E + ++ N + S ++ P + Y V E KA++ P V A G GL G +D +E P LG+ + +A++ +N DGT +V Y+P G Y + + Y E + P V + P D +++ +GPG+ VF+++ + FTV+++P+ G +KA I NP + C V +N DGTY Y+P G H +++TYD VP+ SP+ V V +G PSR++A GPGL+E T +P FTV GAG GGLG+++EGP++++I C DNKDG+CS +Y+P PG YDV+I + HIPGSPF VP+ D+VD SKVK GPGL +G R FTVD+SKAG APL+V V+ V+P ++ G VTY P G + V Y + ++P SPF VL + + KV +G G+ + + +P F I+ RDAGE L + +T + V ++ DGT+ Y D G Y + V YG ++P SP+ + +C GP I + V G+ V V+ + AG G ++ + P G + G + Y K G Y + + F +IPN T T E P+ + D P + V+ PS + P +++N DGT+TV+Y P+E GLHE+ + Y G I SP +FYV+ SG V+AYGPGL YG + A FTIVT+DAG GGL LA+EGPSKAEI CIDNK+GTC V+YLP PGDY I +K+ DKHI GSPFTAKI + ++ SQ+ +G+ +D L ISETD+++L A + +P+GR+E C LKRL N ++GISF P+EVGEHLV++ ++G H+ NSP I V ++EIG+A R K+YG GL++G E F+VDTR+AGYGG+SL++EGPSKV+I+ D DGTC V+Y PT PG YI++ K+AD +VPGSPF V I G + E I R A V+ +G++C+LNL IP N + +A V SPSG EI+ + N +RF+P+E+GVHTVSVK +HVTGSPFQFTVGPL +GG HKV G G+ERG A +F+I+TREAGAG LSIA+EGPSKAEI F D+K+GSCGV+Y EPG+Y SIKFNDEH+P SP+++ PV + +D+R +++ +LQ+ G + A+F I +G G I A V SPS + +S+++ ++Y+V F+P ENG+H + V N S + GSPF+V V V+ G G+ G TG +EFF++T+ AG G L+VTI+GPSKV+++CQE GY Y P APG+Y IS+KYGG NHI+GSPF ++G S S ET S L ++V S T K S V +G GL A +G+++ F+VD AG ++L +GV GP PCEEV++KH+GN ++ V Y V+E+G ++L V+WG +PGSPF + VP Sbjct: 353 DASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEAC-NPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQK--DFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPE---AGMQKVRAWGPGLH--GGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSC--DVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSH---PQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDII--DNYDYSHTVKYTPTQQGNMQVL-VTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG--PCE-AKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAV-------DTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL-GSGVRARVLQSFTVDSSKAGLAPLEVRVLG-PRGLVEPVNVVDNGD-GTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYG---VPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPF----------------TVMVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYP-NSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISG--EGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLV------------PVIAPS---DDARRLTVMSLQESGLKVNQPASFAIRLNG-AKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 2578 HSP 2 Score: 1071.23 bits (2769), Expect = 0.000e+0 Identity = 845/2586 (32.68%), Postives = 1242/2586 (48.03%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYK-ESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS------VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNT---TPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE--EGITKQPQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFT--PSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE--YSVVDFKFPVGPVFDY-------VRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYV--DSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVG---------TTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAV-----NIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDAN--QFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRX---XXXXXXXXXXXIHHGHTG-RINE--FFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWG--NHDVPGSPFEIVV 7621 + E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS +R H+RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGL+WTLILHYSI+MP+WE ++ D K +PKQRLLGWI +K+P+ P+ NF +W DG A+GALVD+CAPGLCP+W WDP++ + NA+EA+ A++ L V +I P E+I+P VDE ++MTYLSQFP A+L APL PK N + RAYG G+E GN + PA FTVDT +AG+G++ + V +P+G KE ++ +K YS Y+P + G +++ + FA I SPF+V+V A GD SKVTA GPG+E VGN + T+F+++TA AG G + + D +G K++V+ + + + Y + G H V +FFAG I SPF V V + N +A A+GRG+QP+GVR+R+ +F+V T+ AG +LGV + GP E + K +Y Y P PG Y + I +G + I SPF V V P K++A+GPGL GGIV + A F VE+ G E G+LGF+I+GPS+AKI+ D DGS +V YWP PGEYAVHI+CDDE+I SPYMA I T ++P V AYGPGL SG N A+F V+ K+AG + +K D GQ I +Q+++ DGTY+C YTP KHT+ V +G VNIP SP++VN+ + + +KV+GPG+ER+ K N T+F VDC AG GD+ + VL E DV N + TF YTI++ F+ EIP SPF+V ++ +D K K + G+ F + T G K + SP L +N +TPT G V V G+PI SP+ V ++ + E + ++ +D + + L+P R V P R N F P EE +Y V T + E P V A+G GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP +PG Y VN+L+ + HI SPF I D +KV A GPGL V + + G G + + ++ ++ NN DGTY+ +Y P G + + + Y G V P V V D SRI+ +GPG+E + + FTVD L G + I P+ A +CF DN DGT V+Y P + G + V + +++ IP SPF V + + S+V+ GPGL+ FT P+ FTV AG L + V + + + G YIP G+ ++ + Y +PGSPF V + +P KV + G G+ G + +V FT+++ AG + LE+ V GP ++V ++GDGT T Y G Y V V Y ++ +P SPF V V + GP L+ VP V ++ ++AG+G+L+ + G + + + G V+Y+P K G Y + + + ++IP R A Q T + SK + S V VG V D V V P + +I N DGT + Y ++ G + + V + G I SPF V ++ +P + GL + D+ F + G ++ V PS A + +DNK+GT V Y P G + + IK+M HI SP + P S G T+ + + L+ + P+ E SC + +G +++ P G++ + V + +HIP SPF + ++ S+VKL F++D L+ SI+ PS + C +NH G +++ P E G +++++K ++V SP ++ IG + + R L E+S ++ GY + +V PS E L D + + P GV+ VS K + HV GSPF + G K I + +A + + E + +S + PS +AEI K+ C V + E G + S+K+ +HV GSPF + P + + + G A F I G +S V PS E + N V ++ E G + V + N+ IP SP+ V + + +G ++N+ F N G + + PS C +E Y ++P+ G +TI +K+ G +H++GSPF V + N P V G GL+ G ++EF ++ AG L V + GP + C+E ++V Y G +L+ V++G NH V GSPF+ V Sbjct: 3 VTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWE----DEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQV-GEACNPNA--CRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGK-APLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTF-TVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAG-KAPLNVQFNSPLPGDAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQG-KLDVTILSP-SRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADI-------EMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEA-----GPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLK----EAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKIN----CRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL----GSGVRARVLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQ--------------TGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVTEEAYVPVSDMN----GLGFKPFDLVIPFAVRK-----GEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYV-NYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNK--DGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDS-RRCSQVKL----------GSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIG---ISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDF----IVDTRDAGYG--GISLAVEGPSKVDIQTE--DLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKIS---GEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEI-VPMGKNSHC-VRFVPQEMGVHTVSVKYRGQHVTGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNG-SHVVGSPFKVRVGEPGQAGN--------------------------PALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQET------PEGYKVMYTPMAPGNYLISVKYGGPNHIV-GSPFKAKV 2447
BLAST of Filamin vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755]) HSP 1 Score: 1333.16 bits (3449), Expect = 0.000e+0 Identity = 858/2294 (37.40%), Postives = 1246/2294 (54.32%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP----YKESKIKAFGPGL--TGGIVSKPAFFEVETN--GETGALGFSIKGPSEA-KIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPST-----VKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS----VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQET--NNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE---YSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX---------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGST-----QKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 ++ +V A GPGLE GN P F + T AG G++ + V +P+G K E+ Y C Y P G + + I FA IP SPF V V A +P+ ASG G++P G + T F V T AG G + + KG ++ VK K + + EY G +S+ + + G I SPF V V + + ++ A G G+ G V A+F V + + LG + GP ++ + + C + Y P+ PG Y V I + I SP+ + P Y ++A+GPGL +G IV+ A F V+ G+ F+ G + I + DG+ +Y P ++ + ++ NIP SPY I + P KV +GPG+ SG+ N+P F V+ AG A + + I N + T++ +Y P G++T+ V + + IP SPF+V V + +A+ +K GPG+ +A + T+F V K AG + + + + ++D+ ++ DN D + T+KYTP G + + + IP+SPF V + + D K K+N L N +G+ EF + T G + + ++ + SP+ VP + A F P G + V V G+P+ SPY V A+ D K + P E L+ A++ ID K + + P E + ++ N + S ++ P + Y V E KA++ P V A G GL G +D +E P LG+ + +A++ +N DGT +V Y+P G Y + + Y E + P V + P D +++ +GPG+ VF+++ + FTV+++P+ G +KA I NP + C V +N DGTY Y+P G H +++TYD VP+ SP+ V V +G PSR++A GPGL+E T +P FTV GAG GGLG+++EGP++++I C DNKDG+CS +Y+P PG YDV+I + HIPGSPF VP+ D+VD SKVK GPGL +G R FTVD+SKAG APL+V V+ V+P ++ G VTY P G + V Y + ++P SPF VL + + KV +G G+ + + +P F I+ RDAGE L + +T + V ++ DGT+ Y D G Y + V YG ++P SP+ + +C GP I + V G+ V V+ + AG G ++ + P G + G + Y K G Y + + F +IPN T T E P+ + D P + V+ PS + P +++N DGT+TV+Y P+E GLHE+ + Y G I SP +FYV+ SG V+AYGPGL YG + A FTIVT+DAG GGL LA+EGPSKAEI CIDNK+GTC V+YLP PGDY I +K+ DKHI GSPFTAKI + ++ SQ+ +G+ +D L ISETD+++L A + +P+GR+E C LKRL N ++GISF P+EVGEHLV++ ++G H+ NSP I V ++EIG+A R K+YG GL++G E F+VDTR+AGYGG+SL++EGPSKV+I+ D DGTC V+Y PT PG YI++ K+AD +VPGSPF V I G + E I R A V+ +G++C+LNL IP N + +A V SPSG EI+ + N +RF+P+E+GVHTVSVK +HVTGSPFQFTVGPL +GG HKV G G+ERG A +F+I+TREAGAG LSIA+EGPSKAEI F D+K+GSCGV+Y EPG+Y SIKFNDEH+P SP+++ PV + +D+R +++ +LQ+ G + A+F I +G G I A V SPS + +S+++ ++Y+V F+P ENG+H + V N S + GSPF+V V V+ G G+ G TG +EFF++T+ AG G L+VTI+GPSKV+++CQE GY Y P APG+Y IS+KYGG NHI+GSPF ++G S S ET S L ++V S T K S V +G GL A +G+++ F+VD AG ++L +GV GP PCEEV++KH+GN ++ V Y V+E+G ++L V+WG +PGSPF + VP Sbjct: 184 DASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEAC-NPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQK--DFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPE---AGMQKVRAWGPGLH--GGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSC--DVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSH---PQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDII--DNYDYSHTVKYTPTQQGNMQVL-VTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG--PCE-AKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAV-------DTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL-GSGVRARVLQSFTVDSSKAGLAPLEVRVLG-PRGLVEPVNVVDNGD-GTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYG---VPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPF----------------TVMVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYP-NSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISG--EGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLV------------PVIAPS---DDARRLTVMSLQESGLKVNQPASFAIRLNG-AKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 2409 HSP 2 Score: 847.81 bits (2189), Expect = 0.000e+0 Identity = 741/2402 (30.85%), Postives = 1107/2402 (46.09%), Query Frame = 2 Query: 719 LCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYK-ESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS------VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPI---GQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE--EGITKQPQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFT--PSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE--YSVVDFKFPVGPVFDY-------VRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYV--DSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVG---------TTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAV-----NIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDAN--QFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRX---XXXXXXXXXXXIHHGHTG-RINE--FFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWG--NHDVPGSPFEIVV 7621 LCP+W WDP++ + NA+EA+ A++ L V +I P E+I+P VDE ++MTYLSQFP A+L APL PK N + RAYG G+E GN + PA FTVDT +AG+G++ + V +P+G KE ++ +K YS Y+P + G +++ + FA I SPF+V+V A GD SKVTA GPG+E VGN + T+F+++TA AG G + + D +G K++V+ + + + Y + G H V +FFAG I SPF V V + N +A + A+GRG+QP+GVR+R+ +F+V T+ AG +LGV + GP E + K +Y Y P PG Y + I +G + I SPF V V P K++A+GPGL GGIV + A F VE+ G E G+LGF+I+GPS+AKI+ D DGS +V YWP PGEYAVHI+CDDE+I SPYMA I T ++P V AYGPGL SG N A+F V+ K+AG + +K D GQ I +Q+++ DGTY+C YTP KHT+ V +G VNIP SP++VN+ + + +KV+GPG+ER+ K N T+F VDC AG GD+ + VL E DV N + TF YTI++ F+ EIP SPF+V ++ +D K K + G+ F + T G K + SP L +N +TPT G V V G+PI SP+ V ++ + E + ++ +D + + L+P R V P R N F P EE +Y V T + E P V A+G GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP +PG Y VN+L+ + HI SPF I D +KV A GPGL V + + G G + + ++ ++ NN DGTY+ +Y P G + + + Y G V P V V D SRI+ +GPG+E + + FTVD L G + I P+ A +CF DN DGT V+Y P + G + V + +++ IP SPF V + + S+V+ GPGL+ FT P+ FTV AG L + V + + + G YIP G+ ++ + Y +PGSPF V + +P KV + G G+ G + +V FT+++ AG + LE+ V GP ++V ++GDGT T Y G Y V V Y ++ +P SPF V V + GP L+ VP V ++ ++AG+G+L+ + G + + + G V+Y+P K G Y + + + ++IP R A Q T + SK + S V VG V D V V P + +I N DGT + Y ++ G + + V + G I SPF V ++ +P + GL + D+ F + G ++ V PS A + +DNK+GT V Y P G + + IK+M HI SP + P S G T+ + + L+ + P+ E SC + +G +++ P G++ + V + +HIP SPF + ++ S+VKL F++D L+ SI+ PS + C +NH G +++ P E G +++++K ++V SP ++ IG + + R L E+S ++ GY + +V PS E L D + + P GV+ VS K + HV GSPF + G K I + +A + + E + +S + PS +AEI K+ C V + E G + S+K+ +HV GSPF + P + + + G A F I G +S V PS E + N V ++ E G + V + N+ IP SP+ V + + +G ++N+ F N G + + PS C +E Y ++P+ G +TI +K+ G +H++GSPF V + N P V G GL+ G ++EF ++ AG L V + GP + C+E ++V Y G +L+ V++G NH V GSPF+ V Sbjct: 13 LCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQV-GEACNPNACR--ASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGK-APLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTF-TVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAG-KAPLNVQFNSPLPGDAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQG-KLDVTILSP-SRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADI-------EMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEA-----GPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLK----EAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKIN----CRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL----GSGVRARVLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQ--------------TGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMVTEEAYVPVSDMN----GLGFKPFDLVIPFAVRK-----GEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYV-NYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNK--DGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSR-RCSQVKL----------GSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIG---ISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDF----IVDTRDAGYG--GISLAVEGPSKVDIQTE--DLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKIS---GEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEI-VPMGKNSHC-VRFVPQEMGVHTVSVKYRGQHVTGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNG-SHVVGSPFKVRVGEPGQAGN--------------------------PALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQET------PEGYKVMYTPMAPGNYLISVKYGGPNHIV-GSPFKAKV 2278
BLAST of Filamin vs. Ensembl Human
Match: FLNB (filamin B [Source:HGNC Symbol;Acc:HGNC:3755]) HSP 1 Score: 1331.62 bits (3445), Expect = 0.000e+0 Identity = 865/2332 (37.09%), Postives = 1257/2332 (53.90%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP----YKESKIKAFGPGL--TGGIVSKPAFFEVETN--GETGALGFSIKGPSEA-KIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPST-----VKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS----VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQET--NNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVI-----DTATKSVK-PAQILP---KSTP--------------------GLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSV------------VDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX---------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGST-----QKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 ++ +V A GPGLE GN P F + T AG G++ + V +P+G K E+ Y C Y P G + + I FA IP SPF V V A +P+ ASG G++P G + T F V T AG G + + KG ++ VK K + + EY G +S+ + + G I SPF V V + + ++ A G G+ G V A+F V + + LG + GP ++ + + C + Y P+ PG Y V I + I SP+ + P Y ++A+GPGL +G IV+ A F V+ G+ F+ G + I + DG+ +Y P ++ + ++ NIP SPY I + P KV +GPG+ SG+ N+P F V+ AG A + + I N + T++ +Y P G++T+ V + + IP SPF+V V + +A+ +K GPG+ +A + T+F V K AG + + + + ++D+ ++ DN D + T+KYTP G + + + IP+SPF V + + D K K+N L N +G+ EF + T G + + ++ + SP+ VP + A F P G + V V G+P+ SPY V A+ D K + P E L+ A++ ID K + + P E + ++ N + S ++ P + Y V E KA++ P V A G GL G +D +E P LG+ + +A++ +N DGT +V Y+P G Y + + Y E + P V + P D +++ +GPG+ VF+++ + FTV+++P+ G +KA I NP + C V +N DGTY Y+P G H +++TYD VP+ SP+ V V +G PSR++A GPGL+E T +P FTV GAG GGLG+++EGP++++I C DNKDG+CS +Y+P PG YDV+I + HIPGSPF VP+ D+VD SKVK GPGL +G R FTVD+SKAG APL+V V+ DT ++S + P + L K P G VTY P G + V Y + ++P SPF VL + + KV +G G+ + + +P F I+ RDAGE L + +T + V ++ DGT+ Y D G Y + V YG ++P SP+ + +C GP I + V G+ V V+ + AG G ++ + P G + G + Y K G Y + + F +IPN A E ++E + +P + E V D P + V+ PS + P +++N DGT+TV+Y P+E GLHE+ + Y G I SP +FYV+ SG V+AYGPGL YG + A FTIVT+DAG GGL LA+EGPSKAEI CIDNK+GTC V+YLP PGDY I +K+ DKHI GSPFTAKI + ++ SQ+ +G+ +D L ISETD+++L A + +P+GR+E C LKRL N ++GISF P+EVGEHLV++ ++G H+ NSP I V ++EIG+A R K+YG GL++G E F+VDTR+AGYGG+SL++EGPSKV+I+ D DGTC V+Y PT PG YI++ K+AD +VPGSPF V I G + E I R A V+ +G++C+LNL IP N + +A V SPSG EI+ + N +RF+P+E+GVHTVSVK +HVTGSPFQFTVGPL +GG HKV G G+ERG A +F+I+TREAGAG LSIA+EGPSKAEI F D+K+GSCGV+Y EPG+Y SIKFNDEH+P SP+++ PV + +D+R +++ +LQ+ G + A+F I +G G I A V SPS + +S+++ ++Y+V F+P ENG+H + V N S + GSPF+V V V+ G G+ G TG +EFF++T+ AG G L+VTI+GPSKV+++CQE GY Y P APG+Y IS+KYGG NHI+GSPF ++G S S ET S L ++V S T K S V +G GL A +G+++ F+VD AG ++L +GV GP PCEEV++KH+GN ++ V Y V+E+G ++L V+WG +PGSPF + VP Sbjct: 353 DASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEAC-NPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQK--DFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPE---AGMQKVRAWGPGLH--GGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSC--DVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSH---PQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDII--DNYDYSHTVKYTPTQQGNMQVL-VTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG--PCE-AKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAV-------DTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL-GSGVRARVLQSFTVDSSKAGLAPLEVRVLGPRADDTDSQSWRSPLKALSEFFKGDPKGDFNKTGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYG---VPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATD-GEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYP-NSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISG--EGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLV------------PVIAPS---DDARRLTVMSLQESGLKVNQPASFAIRLNG-AKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 2633 HSP 2 Score: 1052.74 bits (2721), Expect = 0.000e+0 Identity = 850/2635 (32.26%), Postives = 1247/2635 (47.32%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYK-ESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS------VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPI---GQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE--EGITKQPQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFT--PSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVN-------------------------------LDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE--YSVVDFKFPVGPVFDY-------VRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVD----STIPSGQVTAYGPGLSYGRP-----------DMHAH----FTIVTKDA-GAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVG---------TTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAV-----NIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDAN--QFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRX---XXXXXXXXXXXIHHGHTG-RINE--FFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWG--NHDVPGSPFEIVV 7621 + E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS +R H+RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGL+WTLILHYSI+MP+WE ++ D K +PKQRLLGWI +K+P+ P+ NF +W DG A+GALVD+CAPGLCP+W WDP++ + NA+EA+ A++ L V +I P E+I+P VDE ++MTYLSQFP A+L APL PK N + RAYG G+E GN + PA FTVDT +AG+G++ + V +P+G KE ++ +K YS Y+P + G +++ + FA I SPF+V+V A GD SKVTA GPG+E VGN + T+F+++TA AG G + + D +G K++V+ + + + Y + G H V +FFAG I SPF V V + N +A + A+GRG+QP+GVR+R+ +F+V T+ AG +LGV + GP E + K +Y Y P PG Y + I +G + I SPF V V P K++A+GPGL GGIV + A F VE+ G E G+LGF+I+GPS+AKI+ D DGS +V YWP PGEYAVHI+CDDE+I SPYMA I T ++P V AYGPGL SG N A+F V+ K+AG + +K D GQ I +Q+++ DGTY+C YTP KHT+ V +G VNIP SP++VN+ + + +KV+GPG+ER+ K N T+F VDC AG GD+ + VL E DV N + TF YTI++ F+ EIP SPF+V ++ +D K K + G+ F + T G K + SP L +N +TPT G V V G+PI SP+ V ++ + E + ++ +D + + L+P R V P R N F P EE +Y V T + E P V A+G GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP +PG Y VN+L+ + HI SPF I D +KV A GPGL V + + G G + + ++ ++ NN DGTY+ +Y P G + + + Y G V P V V D SRI+ +GPG+E + + FTVD L G + I P+ A +CF DN DGT V+Y P + G + V + +++ IP SPF V + + S+V+ GPGL+ FT P+ FTV AG L + V + + + G YIP G+ ++ + Y +PGSPF V + +P KV + G G+ G + +V FT+++ AG + LE+ V GP + + ++V ++GDGT T Y G Y V V Y ++ +P SPF V V + GP L+ VP V ++ ++AG+G+L+ + G + + + G V+Y+P K G Y + + + ++IP R A Q T + SK + S V VG V D V V P + +I N DGT + Y ++ G + + V + G I SPF + + V A PG RP DM+ F +V A G ++ V PS A + +DNK+GT V Y P G + + IK+M HI SP + P S G T+ + + L+ + P+ E SC + +G +++ P G++ + V + +HIP SPF + ++ S+VKL F++D L+ SI+ PS + C +NH G +++ P E G +++++K ++V SP ++ IG + + R L E+S ++ GY + +V PS E L D + + P GV+ VS K + HV GSPF + G K I + +A + + E + +S + PS +AEI K+ C V + E G + S+K+ +HV GSPF + P + + + G A F I G +S V PS E + N V ++ E G + V + N+ IP SP+ V + + +G ++N+ F N G + + PS C +E Y ++P+ G +TI +K+ G +H++GSPF V + N P V G GL+ G ++EF ++ AG L V + GP + C+E ++V Y G +L+ V++G NH V GSPF+ V Sbjct: 3 VTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWE----DEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQV-GEACNPNACR--ASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGK-APLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTF-TVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAG-KAPLNVQFNSPLPGDAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQG-KLDVTILSP-SRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADI-------EMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEA-----GPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLK----EAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKIN----CRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL----GSGVRARVLQSFTVDSSKAGLAPLEVRVLGPRADDTDSQSWRSPLKALSEFFKGDPKGDFNKTGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQ--------------TGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGF---RPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYV-NYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNK--DGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDS-RRCSQVKL----------GSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIG---ISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDF----IVDTRDAGYG--GISLAVEGPSKVDIQTE--DLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKIS---GEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEI-VPMGKNSHC-VRFVPQEMGVHTVSVKYRGQHVTGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNG-SHVVGSPFKVRVGEPGQAGN--------------------------PALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQET------PEGYKVMYTPMAPGNYLISVKYGGPNHIV-GSPFKAKV 2502
BLAST of Filamin vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09]) HSP 1 Score: 746.888 bits (1927), Expect = 0.000e+0 Identity = 489/1511 (32.36%), Postives = 764/1511 (50.56%), Query Frame = 2 Query: 3251 ANTPASFIIDSTEEPPAPLGVTIEGPM--EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKF----NEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEI--EVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVR------------PHRGHLIANKVPSLFTINTRDAGE-SDLELMVTGPN-NESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSE-------AKPEQCYIEGPILNEVPVGKTVTIPVNTQNA----GDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPV---GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKI-DNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX--------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSN----------DSIRET-KSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 + P F ID+T+ P + V + +D +DN DG+ +V Y + PG+Y +NV++ E I SP + + P+ DV+ + GL + S + T+N ++ KG+ +I +R + N DGTYS G+HK+ + +D +PV ++ V V +G+D ++ +AYGPGLE+ + + F +DL+GAG+G L + + GPA A+ + D +G CSV+Y+ + PG Y+++IKF ++H+ GSPF + D S++ GL++ R+ P F +D SK + P+K V + ++P S P +V ++P N I E++Y+ +++ + VL EP+ + + + + H GH VP + RD G +E V GP+ E +N +G + + D+ G Y V + V VPV +E E+ I P T P++ + +L+AK + ++N + + K+G + + + E++ + E+ ER E +Y F+F V G + A+V P+ +K+V +I+N DGTI V+Y P G HEL + NG + G+P KFYVD+ G T YGPGL A FT+ K + A LS+++EGP+K++I+ DNK+GTC +++P PG+Y + +K K + SPF + GE +KRS + VG+TS+V L I++ ++ ++A + SP G EE C ++ L G LG+SFTP+E GEHL+ V R G+ +P +PFKI V + ++G+AS+V++ G G G+ + + +VDT AGYGGLS+S++GPSK E+ C + G V Y PTEPG Y I +K+AD +V SP V G + + + I + + + L L + + + TA ++ P G + E+ L + ++F PK G+HT+SV + HV GSPFQFTVG +GG HKV G GV RG N F IY REAG G++++ IEGPSKA ++F+D+ DG+C V Y+V PG+YV ++KFND+H+P SPF + Y P E R + +A QG G F + H G + A V++P+N+ I I D Y++ FVP E G H +HV ++ +P+ SPFR+ V ++ SG+G+ G TG+ EF ++T+NAG G LTV +DGPSK L+ E E GY Y P APG Y S+KY G H GSPF + + G N D++ +T K V G K V +G GL G+ F +D GLAG ++L VGV PCEEV ++H G+ + +Y + ++ + + +++G+ ++PGSPF I Sbjct: 754 SKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNV-------DVSGIRV--EGLENENLLIGSHLRPTINIGKLEPKSKGL--QLIDEVNGKRYNVPMKINPDGTYSTDTPLMEVGEHKLQLLFDEIPVKEA--VVEVIKGTDVNKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKKDPSQITI--SGLDQPNYRLNQPINFVIDTSKTKDLPVKATV-PSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEK--LVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGH-----VP----FDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEVAAR---VPVMAEKIGRKEDVIKEEIVFHPEIAEHSPTVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYEAIGKLEYERIQAERAKVVVEKEDDVDKYEKQYK---FQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDA-YGDGWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKV---------YIAPATGE------VRKLELAQFHGQGIPAGKAFTFTVLTH-RAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNG-IHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAK-------VTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFAI 2204 HSP 2 Score: 456.062 bits (1172), Expect = 2.458e-129 Identity = 357/1116 (31.99%), Postives = 535/1116 (47.94%), Query Frame = 2 Query: 191 EDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIK------FANSEIPNSPFKVNVKNAAG--DPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDS-VKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHT----EDAGFADLGVNVYGP--GRSLEKCQIKKVSPCLYECSYIP-QRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDP--LKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE-TYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLY----NDEHIKDSPFNVTI 3469 +DA+WK+IQ+NTFTRW HL+ + I+ L+ D +DGLKLI L Q LS N +K+ FR+QKLENV++ L F + E ++++NIDS+ I D KLILGL+WTLILHYSI+M W E ++DG K +PKQ+LL WI +++P P+ NFT+DWNDG A+GALV++ APG +W W P AL+N ++A+ +A++ L VAPLI P EMI+P++DE ++MTYLSQFP + P + T S + + +P F + G + + + GQ + +KE AY + PT G + + F IP + V A D +K +VG F V A GP V+ +++D G++ V T E+ F EY GLHSVNVF + + SPF + K S GRGI PEG+R DV V + E+ A++ + V P G L + Y P Q P V +K I + VAP SKI+AFG GL GGIV++P F+VE NGE+ L F+++GPS+A+I C + DGSA ++Y PTV G Y V +L D ++I SP++ ++ + P +VT + + P F V+T+ G K E D I R+ G + P P KH + VS V++P +PF V V E +A+ +K++GPG++ + E T F +D AG G + +++ D++ +V + DN DG+FT+KYT + G +F E EI SP ++ ++ + D ++ L NE ++ GS +RP I + ++L + NG V K NP G T+TPL+ ++ + +++ IPV+ A + ++ ++V NK + AYG GL + V A F +D L + + GP +A+ D G+G CSV Y+ K PG Y + + + EH+K SPF + Sbjct: 20 DDAEWKIIQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALNFFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMG-WIQE--KREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQFPATKPIIMKPKVQATISNLDKIL---------QVNDPREFDLKLSRDG-FKPKVSIRDEDGQDIHLSLKKVEDKENAYKVKFTPTKIGFIHVDVAANDVHTFETQTIPEASVICQVVPIARLLDYNKTA-----------KVGDDVKFAVVDAIEGP--VEAIVVDPTGKEHRMVILDGTSPGEHSF--EYKIPCIGLHSVNVFHKKLPLTGSPFPLRGKPKNSFK------VWGRGIAPEGIRKNDVVGVHVESLDPEENIANANISLEVLKPSDGSHLPVSVGYNDESQSMDFEYSPKQAPDDLEVLVKVAGEVI--ESHKIHVAPESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIP--FRVDTRLCGVDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGVDGPVYSKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGE-EI--SPIEINVKPNVDVSGIRVEGLE--------NENLLI----GSHLRPTINIGKLEPKSKGLQLIDEVNG------------KRYNVPMKINPDGTY----------------STDTPLMEVGEHKL-QLLFDE--IPVKEAVVEVIKGTDV------NKCK----------------------------AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV 1017 HSP 3 Score: 275.789 bits (704), Expect = 9.063e-74 Identity = 327/1356 (24.12%), Postives = 578/1356 (42.63%), Query Frame = 2 Query: 3809 SRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA---GEA-PLKVNVIDTATKSVKPAQIL-----PKS------TPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNT---QNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHY-TTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFY----NGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSK-AEIQCIDNKNGT----CDVSYLPLAPGDYHIGIKF------MDKHIIG-----SPFTAKIFGEPKKRSQICVGTTSD------VPLRISET-DINNLNAIVISPTGREESCTLKRL-QNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGD--GLNDGMVNETCQF-----------------VVDTRNAGYGGLSLSIEGPSKVEIE-----CHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSL-TER---ILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPF-MLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXX--------XXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 S+IRA+G GLE GI +P F V++ G + L ++EGP+ A+I C + DG+ + Y P G Y V + + KHI SPF + + + ++ GL+ + +RV +D SK GE P +V+ V +IL P S TPGLF+ T IP+ +I+V + VPG+PF V + K+ + G GV + +K P+ FTI+ AG +E+ + E+V+LDV ++ DG+FT +Y PG Y + V++ + + SP + V +EG + +G + +N + G+ V VP I + G + ++G +++QL+F++ IP +++ + + + + + EQ+ + E +V + G + + P+ + R+ + G+G +V+Y G +E+ + + + + GSPFK VD Q+T G R + +F I T + L + PS A++Q + +++ + +V ++P + I I+ +D+ ++ P KI + KK S T++ VP + + ++ + + V P G+E ++ QNG +SF GE+ V +G+ + A+RV + + G + ++ E F + + + + + P V +E + H + + T+ GT ++V Y +V + IG + ER ++ +D + + + N+ GY ++ A V+ P+ E+ EII D +++ PK G H +S+ + + G+P +F V DG + G G++ + + FT+ + + A LS++IEGP+K++I DNKDG+C + PG+Y +K + V SPF +L + E S+ ++GS + + ISA + SP E+ + +D + V F P E G H + V + +P +PF++ +V VSG G G T + NE VDTS AG G L+V++ GPSK +L C+E +SG Y P PG Y I+IK+ ++H+ SP V +G KS + + I QK +V+ G L E + F+ + D+ + P +++ ++ LG +Q+ + + +G H L V + + V GSPF+ V Sbjct: 547 SKIRAFGAGLEGGIVNEPCVFDVEMNGESKD-LSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIE---------GLKPSATRVTG-----IDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGV----DGPVYSKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNVDVSGIRVEGLENENLLIGSHLRPTINIGKLEPKSKGLQLIDEVNGKRYNVPMKINPD--GTYSTDTPLMEVGEHKLQLLFDE--IP---VKEAVVEVIKGTDVNKCKAYGPGLEQA---VVGEKAVFELDLD-GAGEGALSMEMRGPAKAES--RIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKKDPSQITISGLDQPNYRLNQPINFVIDT--SKTKDLPVKATVPSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPFDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEV----------------AARVPVMAEKIGRKEDVIKEEIVFHPEIAEHSPTVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYEA-IGKLEYERIQAERAKVVVEKEDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGDGW---ATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSH--------------------------LSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKF-ADHHVKDSPLTVQCTG------------KSAGRVIQTI----QK------DVEQHGICLPDQE---SHLFLKLLNTSPMDIT-ARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTV 1793 HSP 4 Score: 210.69 bits (535), Expect = 6.120e-54 Identity = 223/883 (25.25%), Postives = 379/883 (42.92%), Query Frame = 2 Query: 1964 DCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTG-QTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNG-----------DGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDN--DFKKYKINNLNNTTPIG-QLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFV-AGFTPTVIGPHTVTVECKGNPIGNSPY----------KVIATDRVNTKEY----PETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQ--RSNFEPNEEIIYPVQRTNEKAELR---------------KPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDG-TYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIH-----------------DIV----------------DVSKVKCYGPGLERNGSRVF--TPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTY-IPENIGNCEIEVLYNNMQVPGSPF 4354 + +DN DG+ V Y P V G + + IL + + +P I+ + T YGPGL + + +PA F V K S K + G ++I DN DGT S + P +PG++ V V G + +SPF+V V+ G G +R+ ++ + ++ + + ++++ + G DG + I + +P++PFK+ ++ D K +++ I Q NE + T G + V+ P S+ + +E +G + +TPT G + + ++ + + +SP +VI T + + +++ P+ E+ L + K N + + + + P ++ + +Q + F P E I+ + + A + V A G+G+V+G T +F I E + VTIEGP +A +++ D+ DG C V+Y PG Y+V V +ND+HI DSPF V I P T + + +G G+ P G +F+ FTV + KG ++A + P N+ T + DG +Y+ + P G H I +T DG P+ +SP+ + V DP+ I A G GL +G T Q +F ++ AG G L + ++GP+ A + ++ + G V+Y P PGSY S+K+N H PGSPF +P+ D V D +KV G GL ++ F P+ F +D AG L V V+ TK ++ G + +Y IP+ + + + Y + ++PGSPF Sbjct: 1381 EIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTP----IKFYVDAYGDGWATVYGPGLQNAV-VGEPATFTVCAKG----SQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM-----------GEGQKRSHLSV----------GSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGL-SVSVQGP--SKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFL--------KLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPAT---GEVRKLELAQFHGQGI-PAG---KAFT-FTV----LTHRAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGL----NKFFPGRPAAFQIDTGLAGTNLLMVGVV--TTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGF-VFIKYGDKEIPGSPF 2202 HSP 5 Score: 203.371 bits (516), Expect = 8.983e-52 Identity = 234/854 (27.40%), Postives = 345/854 (40.40%), Query Frame = 2 Query: 3218 TAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----GEAPLKVNVIDTATKSVKPAQILPKSTPG----------LFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCE--PEKVIVTGEG-VRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPF---IVPVHSEA-KPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGP-----VGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQ-PSESGL--HELE------------------VFYNGQPITGSPFKFYVD----------------------------STIP-----SGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAV---EGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFT 5524 T YG GL V PA+F + + L V+IEGP +++I DN DGTCS ++P PG Y V+V + +KDSPF V + + + S++ S + A PI + A I +P C V G S++P G+H I + DG V K+P+ + V Q D S++ G G +GIT Q + VD AG GGL +S++GP+ A++ C + K G V Y P +PG Y ++IKF + H+ SP T V+C G ++ RV Q V+ E+ L + +++T+ + + PK + + + P+ G + V+Y + V GSPF V + E KV G+G VR G A F I R+AG + + + GP+ + L+ +H DG YK PG Y V V + ++++P SPF I P E K E G +P GK T V T A G L AK V P +IVP + E Y + +VP++ G + + + + +R+ F+ + + P T S G V+N N G G +TVQ PS++ L +ELE V YNG GSPFK V+ + +P + +VTA G GL+ P A F I T AG L + V +GP + E+ +G SY + IK+ DK I GSPF Sbjct: 1431 TVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHL---------------------SVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLT-----------VQCTG----KSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNA------FNIYHREAGVGAVAVTIEGPSKAT--LEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHG---QGIPAGKAFTFTVLTHRA-KGHLEAKVVTPNNEVDTIDIVPIE-DGESYA---MRFVPKETGNHFIHVTLD-----GAPMRESPFRLRVG----------GKDLCDP---TAISASGDGLVKGTTGQKCEFVINTA----------NAGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCE-EVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFA 2203 HSP 6 Score: 169.474 bits (428), Expect = 2.211e-41 Identity = 331/1505 (21.99%), Postives = 569/1505 (37.81%), Query Frame = 2 Query: 3350 IDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPF-NQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP----QKFTVD-LEGAGQGGLGLSIEGPADAQ----IQCFDNKDGTCSVQYLP-QKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNV---LNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDL--ELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYI-----EGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENI--------PNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKF----MDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISE-----TDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNA----------SRVKLYGDGLNDGM--------VNETCQFVVDTRNAG-YGGLSLSIEGPSKVEIECH---DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGS-PFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTA--SVISPSGSFEMCEIIALSDNQF----SIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPL----IDGGPHKVHIMGS-GVERGLANDANQFTIYTREAGAGSLSIAIEGPS-KAEI-DFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQ---YSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNC-----QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 +++ + V + P + G V+V ND H F P+ + +A++ Y N T D V+A +G V+AI+ +P + +D G +S Y G H +++ + +P+ SP+ + +G + + +G G+ EGI K ++D E + L + P+D ++++ + +Y P Q P +V +K + I V SK++ +G GLE G V P F V+ + GE+ ++ +K+ Q P + L +Y P G ++ VL + + SPFV V + +P VT G+ + + + K+P F ++TR G DL ++ + P ++ G F D P + + V +VPG+PF V V + I +GP+ ++ P T ++ AG G + G V + + + G TV Y Q+ GAY++ ++F E I PN + + E ++ +H +R ++ + P ++ + R +VP IN DGT + E G H+L++ ++ P+ + + + + + AYGPGL A F + AG G LS+ + GP+KAE + D NG C V Y+ APGDY + IKF +H+ GSPF A + K SQI + R+++ D + + + T + L+ + +S +P H V + SG+ + P +I +I +K+ D D + + D R+ G + + GP E H +G V++ G Y + V P G + E I+ H + AE S V N I ++ A + + + + I L DN I F +LG +T+ V HV ++ +G L I KV + V++ QF + L + P+ K E+ + DN DG+ V Y G + SI N + G+P +D + D + ++ Q +G A F + G +S + P+ K Q+ KI +N+ S +VP G + VHV + + SPFRV+V H G +E + + ++ +I P ++ C G +FT P G++ I++K G + +PF + + TQ G + V+ G G + NE +VD AG L V V GP + E+ K + + +V Y E G + + +++ +H V SP + Sbjct: 309 VEDKENAYKVKFTPTKIGFIHVDVAANDVHT----FETQTIPEASVICQVVPIARLLDY----NKTAKVGDDVKFAVVDAI------EGPVEAIVVDPTGKEHRMVILDGTSPGEHSFEYKIPCIGLHSVNVFHKKLPLTGSPFPL---RGKPKNSFKVWGRGIAPEGIRKNDVVGVHVESLDPEENIANANISLEVLKPSDGSHLPVSVGYNDESQSMDFEYSPKQAPDDLEVLVKVAGEVIESHKIHVAPE---SSSKIRAFGAGLE--GGIVNEPCVFDVEMN--GESKDLSFAVEGPSKAEIGCQERPDGSAIL---SYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVT--GIDESKVYNVGEKIP--FRVDTRLCG-VDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGVDGPVYSKEPTRFT----IDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEISPIEINVKPNVDVSGIRVEGLENENLLIGSH----------LRPTINIGKLE----PKSKGLQLIDEVNGKRYNVPMKINP-DGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVIKGTDV--NKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKA-VVDYKKDPSQITISGLDQPNYRLNQPINFVIDTSKTKDLPVKATVPSDFAQLQPV------VSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPFDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEVAARVPVMAEKIGRKEDVIKEEIVFHPEIAEHSP--TVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYE-AIGKLEYERIQAERAKVVVEKEDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDA----------------YGDG-WATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPA-KSQI----KIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRS---HLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFT--PREAGEHLITVKRDG-KLVPKAPFKIKVD-------------------------KTQVGDAS--KVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKA--ELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTV 1693 HSP 7 Score: 135.961 bits (341), Expect = 2.834e-31 Identity = 130/546 (23.81%), Postives = 238/546 (43.59%), Query Frame = 2 Query: 926 KTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNV-KNAAGDPSKVTASG----PGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIE--YTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDV-AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES---KIKAFGPGLTGGIVSKPAFFEV-ETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDG-TYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 K + RV G G + ++G+ + + + + +P G +EPC + L S+ P GE+ I +K +P +PFK+ V K GD SKV SG GI NE V T++AG G + + + K ++T + LI+ YT E G++++ + FA ++ SP V + K++ + + ++ G+ + D + + + D+ + P + +++ + Y+ + P+ G + + + Y + ++ SPF V + E K++A G G+ G F + GA+ +I+GPS+A ++ D+ DG+ +V Y PGEY V + +D++IP SP+ I T L++ + GI K F V T A ++A+ + + I DG +Y+ R+ PK G H + V+ + ESPF++ V + + I G G+ + T + FV++ AG+G + + + Sbjct: 1506 KDSPFRVLVMGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLG--VSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANE------LLVDTSKAGYGGLSVSV------QGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSA---GRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHG---QGIPAGKAFTFTVLTHRA--KGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQM 2029 HSP 8 Score: 132.88 bits (333), Expect = 2.244e-30 Identity = 196/870 (22.53%), Postives = 328/870 (37.70%), Query Frame = 2 Query: 1304 FNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVE---TNGETGALGFSIKGPSEAKIDCVDN--GDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLD-TKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAG---------SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI---ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFV-AGFTPTVIGPHTVTVECKGNPIGNSPYKVI---ATDRVNTKEYPE------------TETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNF--------EPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTI---------YPDTKSSSNID------------------DVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSY 3706 FNV P ++ +++ +K+ + I + L++YT K G H +++ G Q+Q +P V + +AT G + V + A F V + + +L V++ GP +S K K C +++P PG Y V +K G + SPF V V G G +S + EV T E + SIK P + C G V++ P GE+ + + D + +PK+P+ +I++D T++ D KV G G GI T + + +V+T AG PS + C +V G YTP PG + + + + + ++ +SP V I+ +E+ + E++ + DI ++D K + D G + +T+ + + +A + SPF+ + S ++ +K+ G+ F + + V S+ ++ ++ N+G + G + V V+ I +SP+KV AT V E + T T L A ++ K P+ V + + P+E K+ N P E + + R K ++A G+GLVKG F+I++ L V ++GP +A +D + G V Y P PGSY +V YN H SPF + + Y +T S ID D AKVTA G GLN F + F ++ G ++ + V + G Y CSY Sbjct: 1354 FNVRDLGYQPKDLEAIVMPPTQKKEVAE--IIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGD------GWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTC--SAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLV----------MGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPF--KIKVDKTQVGDASKVEVSGSGKAKGI-TLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEV------------KSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQ-QYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHGQGIPAGKAFTFTVLTHRAKGHLEAKVVT-PNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRL-RVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNET-SHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNK--FFPGRPAAFQIDT---GLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSY 2178 HSP 9 Score: 123.25 bits (308), Expect = 2.038e-27 Identity = 201/876 (22.95%), Postives = 346/876 (39.50%), Query Frame = 2 Query: 953 YGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVD--CVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG--------------------ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFD---PLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTG-QTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEA-GNAANIKV---YGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINN-----LNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLG---VTIEGPM-EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNV 3463 YGPGL+ +G PA FTV + L + + P K +I D NK+ S +++P + GEY++ +K + +SPF+V V S ++ V + ++ + + PG ++ C + G + + +T +E G H + V G + +PF + V KT DA + +G G + +G+ ++ E V T AG+ L V+V GP ++ C K+V L + Y P PG Y + IK+ ++ + SP V G + G V + +VE +G + A KG ++ I+ D G + + P + G + + ++ D ++ SP+ Q F KV A G G++ G T F + + AG V A + G ++ +D+NDG Y PG++ V V + + +IP+SPFKV + A G +++ +G GI K T+ V+ + G + + + ++ + +V + DG + I + A + +SPF++ + + I+ + TT GQ EF I T G+ + + V+ S+ + E G+ +TP G + +V+ G SP+K+ V KE + YN+ S K+ V +++ T + + P + + VTA G GL K PA+F ID+ L VT +GP E + + +G CS + G V + Y D+ I SPF + Sbjct: 1433 YGPGLQ--NAVVGEPATFTVCAKGSQAKELSVSIEGP--AKSQIKIHD--NKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVG--STSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDG--------------GRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKV-DKTQVGDASKVEVSGSG-KAKGITLQ-ANELLVDTSKAGYGGLSVSVQGPSKAELTC--KEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCT------------GKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTD-DIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPF----QFTVGSFSEGGAHKVRAAGQGVVRG-ETGTFNAFNIYHREAG----VGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHGQGIPAGKAF--TFTVLTHRAKGHLEAKVVTPNNEVDTIDIVPIE--DGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTT--GQKCEFVINTANAGAGI---LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKI----PVEGKE---------------LGGNGYNETS----HVKIDAVAKTSKGTVA---------------VVPEYQGD------AAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKG--FVFIKYGDKEIPGSPFAI 2204 HSP 10 Score: 106.301 bits (264), Expect = 3.335e-22 Identity = 90/370 (24.32%), Postives = 162/370 (43.78%), Query Frame = 2 Query: 1424 IEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGF--ADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 I +T + G ++++VF+ G + + + + A++A + + + +FQ + D G+ DL V P + E +I Y P+ G + + I + +P V Y + +GPGL +V +PA F V G + L SI+GP++++I DN DG+ + + P VPGEY VH+ + + SP+ + + + L V ST++ A I + G +++K+ G P +R + G +TP+ G+H + V +P++PFK+ V + G+A+ ++V G G + T +VD AG G + +SV Sbjct: 1291 IVFTATKLGTNTLDVFYGGEHVDHVEYEAIGKLEYERIQAERAKVVVEK-EDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGDGWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVG----------STSEVALPITQQELKGISASIKSPG----GIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSV 1645 HSP 11 Score: 103.605 bits (257), Expect = 1.932e-21 Identity = 125/476 (26.26%), Postives = 198/476 (41.60%), Query Frame = 2 Query: 986 IGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSC----------SYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIE-PVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES-----------KIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILC----DDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGIST-----NKPADFIVNT-KNAGSPSTVKAECFDVTGQTIPVQIRD-NNDGTYSCRYTP 2311 +G PF VDT G + L PK EI D ++Y + IP +++I + A +P +PF V VK D SK+ GPG++ PV ++ T F + +AGPG+V+ + D +G ++V + + F ++YT + G + +NV FAG +I SP + V S G+RV + + + + P +S I +V+ Y G Y D H D P KE+ K KA+GPGL +V + A FE++ +G GAL ++GP++A+ D G+G +V Y PG+Y + I E++ SP+ A + DP ++T ISG+ N+P +F+++T K P VKA Q PV R +N ++ R+ P Sbjct: 657 VGEKIPFRVDTRLCG------VDLVPK-----VEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPT-DASKLKIFGPGVDGPVYSK--EPTRFTIDATQAGPGAVEVALRDDQG--ENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNVDVS---------------GIRVEGLENENLLIGSHLRPTINIGKLEP-KSKGLQLIDEVNGKRYNVPMKINPDGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVIKGTDVNKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKK---DPSQIT------ISGLDQPNYRLNQPINFVIDTSKTKDLP--VKATVPSDFAQLQPVVSRSPSNPRHHNVRFVP 1087 HSP 12 Score: 73.9442 bits (180), Expect = 1.947e-12 Identity = 111/492 (22.56%), Postives = 215/492 (43.70%), Query Frame = 2 Query: 929 TNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNE---VGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNP----IHLSPFNVDVAPYKE--SKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSE-AKIDCVDNGDGS----ANVTYWP------TVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDN-NDGTYSCRYTPKIPGKHTVI 2338 T++ +++ +GPG++ + P FT+D AG G +++ + + +G+ ++ D N++ +++ Y G Y++ + FA EI SP ++NVK V SG +E + NE +G + + P S ++D G++ +V KI + + + E G H + + F + ++ + V+ +D + A G G+ E V + A F++ + AG L + + GP ++ + Q + C E Y+ + PG Y + IK+G + + SPF V YK+ S+I G +++P F ++T+ +T L PS+ A++ V + S NV + P ++P E L DE + K + QL L D K + + + S F + ++ G+ +++ F G+ +R +G Y + + G++ V+ Sbjct: 736 TDASKLKIFGPGVDGPVYS-KEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLD--NQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVK------PNVDVSGIRVEGLENENLLIGSHLRPTINIGKLEPKSKGLQLIDEVNGKRYNVPMKIN--PDGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVI-----KGTDVNKCKAYGPGL--EQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVE--YVAKAPGDYEMAIKFGKDEQKEHVKGSPFKA-VVDYKKDPSQITISGLDQPNYRLNQPINFVIDTS-KTKDLPVKATVPSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPF--DVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVV 1201 HSP 13 Score: 65.855 bits (159), Expect = 5.601e-10 Identity = 83/312 (26.60%), Postives = 132/312 (42.31%), Query Frame = 2 Query: 974 EGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNA-AGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILD--TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSK---------TSNSDAKQAYATGRGI-------QPEGVRVRDV------------AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSY-IPQRPGPYVVDIKYGNNPIHLSPFNVD 1813 +G G FTV T A KG+L+ V+ P + + +I + E +Y+ ++P G + I + + + SPF++ V DP+ ++ASG G+ V G++ F + TA AG G + V +D +K D+ + E + + YT G + +V + G+ SPF + V K TS+ T +G Q + +V A FQ+ T AG L V V E+ ++ Y CSY IP R +V IKYG+ I SPF ++ Sbjct: 1906 QGIPAGKAFTFTVLTHRA-KGHLEAKVVTPNNEVDTIDIVPIEDGE-SYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGL--VKGTTGQKCEFVINTANAGAG-ILTVQMDGPSKATLDAY------ELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVF-IKYGDKEIPGSPFAIE 2205
BLAST of Filamin vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09]) HSP 1 Score: 746.117 bits (1925), Expect = 0.000e+0 Identity = 489/1511 (32.36%), Postives = 764/1511 (50.56%), Query Frame = 2 Query: 3251 ANTPASFIIDSTEEPPAPLGVTIEGPM--EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKF----NEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEI--EVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVR------------PHRGHLIANKVPSLFTINTRDAGE-SDLELMVTGPN-NESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSE-------AKPEQCYIEGPILNEVPVGKTVTIPVNTQNA----GDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPV---GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKI-DNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX--------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSN----------DSIRET-KSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 + P F ID+T+ P + V + +D +DN DG+ +V Y + PG+Y +NV++ E I SP + + P+ DV+ + GL + S + T+N ++ KG+ +I +R + N DGTYS G+HK+ + +D +PV ++ V V +G+D ++ +AYGPGLE+ + + F +DL+GAG+G L + + GPA A+ + D +G CSV+Y+ + PG Y+++IKF ++H+ GSPF + D S++ GL++ R+ P F +D SK + P+K V + ++P S P +V ++P N I E++Y+ +++ + VL EP+ + + + + H GH VP + RD G +E V GP+ E +N +G + + D+ G Y V + V VPV +E E+ I P T P++ + +L+AK + ++N + + K+G + + + E++ + E+ ER E +Y F+F V G + A+V P+ +K+V +I+N DGTI V+Y P G HEL + NG + G+P KFYVD+ G T YGPGL A FT+ K + A LS+++EGP+K++I+ DNK+GTC +++P PG+Y + +K K + SPF + GE +KRS + VG+TS+V L I++ ++ ++A + SP G EE C ++ L G LG+SFTP+E GEHL+ V R G+ +P +PFKI V + ++G+AS+V++ G G G+ + + +VDT AGYGGLS+S++GPSK E+ C + G V Y PTEPG Y I +K+AD +V SP V G + + + I + + + L L + + + TA ++ P G + E+ L + ++F PK G+HT+SV + HV GSPFQFTVG +GG HKV G GV RG N F IY REAG G++++ IEGPSKA ++F+D+ DG+C V Y+V PG+YV ++KFND+H+P SPF + Y P E R + +A QG G F + H G + A V++P+N+ I I D Y++ FVP E G H +HV ++ +P+ SPFR+ V ++ SG+G+ G TG+ EF ++T+NAG G LTV +DGPSK L+ E E GY Y P APG Y S+KY G H GSPF + + G N D++ +T K V G K V +G GL G+ F +D GLAG ++L VGV PCEEV ++H G+ + +Y + ++ + + +++G+ ++PGSPF I Sbjct: 756 SKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNV-------DVSGIRV--EGLENENLLIGSHLRPTINIGKLEPKSKGL--QLIDEVNGKRYNVPMKINPDGTYSTDTPLMEVGEHKLQLLFDEIPVKEA--VVEVIKGTDVNKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKKDPSQITI--SGLDQPNYRLNQPINFVIDTSKTKDLPVKATV-PSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEK--LVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGH-----VP----FDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEVAAR---VPVMAEKIGRKEDVIKEEIVFHPEIAEHSPTVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYEAIGKLEYERIQAERAKVVVEKEDDVDKYEKQYK---FQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDA-YGDGWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKV---------YIAPATGE------VRKLELAQFHGQGIPAGKAFTFTVLTH-RAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNG-IHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAK-------VTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFAI 2206 HSP 2 Score: 450.669 bits (1158), Expect = 1.252e-127 Identity = 357/1118 (31.93%), Postives = 535/1118 (47.85%), Query Frame = 2 Query: 191 EDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMP--HKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIK------FANSEIPNSPFKVNVKNAAG--DPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDS-VKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHT----EDAGFADLGVNVYGP--GRSLEKCQIKKVSPCLYECSYIP-QRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDP--LKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE-TYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLY----NDEHIKDSPFNVTI 3469 +DA+WK+IQ+NTFTRW HL+ + I+ L+ D +DGLKLI L Q LS N +K+ FR+QKLENV++ L F + E ++++NIDS+ I D KLILGL+WTLILHYSI+M W E ++DG K +PKQ+LL WI +++P P+ NFT+DWNDG A+GALV++ APG +W W P AL+N ++A+ +A++ L VAPLI P EMI+P++DE ++MTYLSQFP + P + T S + + +P F + G + + + GQ + +KE AY + PT G + + F IP + V A D +K +VG F V A GP V+ +++D G++ V T E+ F EY GLHSVNVF + + SPF + K S GRGI PEG+R DV V + E+ A++ + V P G L + Y P Q P V +K I + VAP SKI+AFG GL GGIV++P F+VE NGE+ L F+++GPS+A+I C + DGSA ++Y PTV G Y V +L D ++I SP++ ++ + P +VT + + P F V+T+ G K E D I R+ G + P P KH + VS V++P +PF V V E +A+ +K++GPG++ + E T F +D AG G + +++ D++ +V + DN DG+FT+KYT + G +F E EI SP ++ ++ + D ++ L NE ++ GS +RP I + ++L + NG V K NP G T+TPL+ ++ + +++ IPV+ A + ++ ++V NK + AYG GL + V A F +D L + + GP +A+ D G+G CSV Y+ K PG Y + + + EH+K SPF + Sbjct: 20 DDAEWKIIQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALNFFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMG-WIQE--KREDGDNKEETPKQKLLNWIRNRLPVSGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQFPATKPIIMKPKVQATISNLDKIL---------QVNDPREFDLKLSRDG-FKPKVSIRDEDGQDIHLSLKKVEDKENAYKVKFTPTKIGFIHVDVAANDVHTFETQTIPEASVICQVVPIARLLDYNKTA-----------KVGDDVKFAVVDAIEGP--VEAIVVDPTGKEHRMVILDGTSPGEHSF--EYKIPCIGLHSVNVFHKKLPLTGSPFPLRGKPKNSFK------VWGRGIAPEGIRKNDVVGVHVESLDPEENIANANISLEVLKPSDGSHLPVSVGYNDESQSMDFEYSPKQAPDDLEVLVKVAGEVI--ESHKIHVAPESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIP--FRVDTRLCGVDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGVDGPVYSKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGE-EI--SPIEINVKPNVDVSGIRVEGLE--------NENLLI----GSHLRPTINIGKLEPKSKGLQLIDEVNG------------KRYNVPMKINPDGTY----------------STDTPLMEVGEHKL-QLLFDE--IPVKEAVVEVIKGTDV------NKCK----------------------------AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV 1019 HSP 3 Score: 275.018 bits (702), Expect = 1.482e-73 Identity = 327/1356 (24.12%), Postives = 578/1356 (42.63%), Query Frame = 2 Query: 3809 SRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA---GEA-PLKVNVIDTATKSVKPAQIL-----PKS------TPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNT---QNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHY-TTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFY----NGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSK-AEIQCIDNKNGT----CDVSYLPLAPGDYHIGIKF------MDKHIIG-----SPFTAKIFGEPKKRSQICVGTTSD------VPLRISET-DINNLNAIVISPTGREESCTLKRL-QNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGD--GLNDGMVNETCQF-----------------VVDTRNAGYGGLSLSIEGPSKVEIE-----CHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSL-TER---ILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPF-MLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXX--------XXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 S+IRA+G GLE GI +P F V++ G + L ++EGP+ A+I C + DG+ + Y P G Y V + + KHI SPF + + + ++ GL+ + +RV +D SK GE P +V+ V +IL P S TPGLF+ T IP+ +I+V + VPG+PF V + K+ + G GV + +K P+ FTI+ AG +E+ + E+V+LDV ++ DG+FT +Y PG Y + V++ + + SP + V +EG + +G + +N + G+ V VP I + G + ++G +++QL+F++ IP +++ + + + + + EQ+ + E +V + G + + P+ + R+ + G+G +V+Y G +E+ + + + + GSPFK VD Q+T G R + +F I T + L + PS A++Q + +++ + +V ++P + I I+ +D+ ++ P KI + KK S T++ VP + + ++ + + V P G+E ++ QNG +SF GE+ V +G+ + A+RV + + G + ++ E F + + + + + P V +E + H + + T+ GT ++V Y +V + IG + ER ++ +D + + + N+ GY ++ A V+ P+ E+ EII D +++ PK G H +S+ + + G+P +F V DG + G G++ + + FT+ + + A LS++IEGP+K++I DNKDG+C + PG+Y +K + V SPF +L + E S+ ++GS + + ISA + SP E+ + +D + V F P E G H + V + +P +PF++ +V VSG G G T + NE VDTS AG G L+V++ GPSK +L C+E +SG Y P PG Y I+IK+ ++H+ SP V +G KS + + I QK +V+ G L E + F+ + D+ + P +++ ++ LG +Q+ + + +G H L V + + V GSPF+ V Sbjct: 549 SKIRAFGAGLEGGIVNEPCVFDVEMNGESKD-LSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIE---------GLKPSATRVTG-----IDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGV----DGPVYSKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNVDVSGIRVEGLENENLLIGSHLRPTINIGKLEPKSKGLQLIDEVNGKRYNVPMKINPD--GTYSTDTPLMEVGEHKLQLLFDE--IP---VKEAVVEVIKGTDVNKCKAYGPGLEQA---VVGEKAVFELDLD-GAGEGALSMEMRGPAKAES--RIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKKDPSQITISGLDQPNYRLNQPINFVIDT--SKTKDLPVKATVPSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPFDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEV----------------AARVPVMAEKIGRKEDVIKEEIVFHPEIAEHSPTVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYEA-IGKLEYERIQAERAKVVVEKEDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGDGW---ATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSH--------------------------LSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKF-ADHHVKDSPLTVQCTG------------KSAGRVIQTI----QK------DVEQHGICLPDQE---SHLFLKLLNTSPMDIT-ARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTV 1795 HSP 4 Score: 210.305 bits (534), Expect = 8.156e-54 Identity = 223/883 (25.25%), Postives = 379/883 (42.92%), Query Frame = 2 Query: 1964 DCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTG-QTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNG-----------DGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDN--DFKKYKINNLNNTTPIG-QLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFV-AGFTPTVIGPHTVTVECKGNPIGNSPY----------KVIATDRVNTKEY----PETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQ--RSNFEPNEEIIYPVQRTNEKAELR---------------KPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDG-TYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIH-----------------DIV----------------DVSKVKCYGPGLERNGSRVF--TPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTY-IPENIGNCEIEVLYNNMQVPGSPF 4354 + +DN DG+ V Y P V G + + IL + + +P I+ + T YGPGL + + +PA F V K S K + G ++I DN DGT S + P +PG++ V V G + +SPF+V V+ G G +R+ ++ + ++ + + ++++ + G DG + I + +P++PFK+ ++ D K +++ I Q NE + T G + V+ P S+ + +E +G + +TPT G + + ++ + + +SP +VI T + + +++ P+ E+ L + K N + + + + P ++ + +Q + F P E I+ + + A + V A G+G+V+G T +F I E + VTIEGP +A +++ D+ DG C V+Y PG Y+V V +ND+HI DSPF V I P T + + +G G+ P G +F+ FTV + KG ++A + P N+ T + DG +Y+ + P G H I +T DG P+ +SP+ + V DP+ I A G GL +G T Q +F ++ AG G L + ++GP+ A + ++ + G V+Y P PGSY S+K+N H PGSPF +P+ D V D +KV G GL ++ F P+ F +D AG L V V+ TK ++ G + +Y IP+ + + + Y + ++PGSPF Sbjct: 1383 EIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTP----IKFYVDAYGDGWATVYGPGLQNAV-VGEPATFTVCAKG----SQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM-----------GEGQKRSHLSV----------GSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGL-SVSVQGP--SKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFL--------KLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPAT---GEVRKLELAQFHGQGI-PAG---KAFT-FTV----LTHRAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGL----NKFFPGRPAAFQIDTGLAGTNLLMVGVV--TTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGF-VFIKYGDKEIPGSPF 2204 HSP 5 Score: 202.986 bits (515), Expect = 1.218e-51 Identity = 234/854 (27.40%), Postives = 345/854 (40.40%), Query Frame = 2 Query: 3218 TAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----GEAPLKVNVIDTATKSVKPAQILPKSTPG----------LFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCE--PEKVIVTGEG-VRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPF---IVPVHSEA-KPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGP-----VGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQ-PSESGL--HELE------------------VFYNGQPITGSPFKFYVD----------------------------STIP-----SGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAV---EGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFT 5524 T YG GL V PA+F + + L V+IEGP +++I DN DGTCS ++P PG Y V+V + +KDSPF V + + + S++ S + A PI + A I +P C V G S++P G+H I + DG V K+P+ + V Q D S++ G G +GIT Q + VD AG GGL +S++GP+ A++ C + K G V Y P +PG Y ++IKF + H+ SP T V+C G ++ RV Q V+ E+ L + +++T+ + + PK + + + P+ G + V+Y + V GSPF V + E KV G+G VR G A F I R+AG + + + GP+ + L+ +H DG YK PG Y V V + ++++P SPF I P E K E G +P GK T V T A G L AK V P +IVP + E Y + +VP++ G + + + + +R+ F+ + + P T S G V+N N G G +TVQ PS++ L +ELE V YNG GSPFK V+ + +P + +VTA G GL+ P A F I T AG L + V +GP + E+ +G SY + IK+ DK I GSPF Sbjct: 1433 TVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHL---------------------SVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLT-----------VQCTG----KSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNA------FNIYHREAGVGAVAVTIEGPSKAT--LEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHG---QGIPAGKAFTFTVLTHRA-KGHLEAKVVTPNNEVDTIDIVPIE-DGESYA---MRFVPKETGNHFIHVTLD-----GAPMRESPFRLRVG----------GKDLCDP---TAISASGDGLVKGTTGQKCEFVINTA----------NAGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCE-EVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFA 2205 HSP 6 Score: 168.318 bits (425), Expect = 3.889e-41 Identity = 331/1505 (21.99%), Postives = 569/1505 (37.81%), Query Frame = 2 Query: 3350 IDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPF-NQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP----QKFTVD-LEGAGQGGLGLSIEGPADAQ----IQCFDNKDGTCSVQYLP-QKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNV---LNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDL--ELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYI-----EGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENI--------PNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKF----MDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISE-----TDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNA----------SRVKLYGDGLNDGM--------VNETCQFVVDTRNAG-YGGLSLSIEGPSKVEIECH---DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGS-PFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTA--SVISPSGSFEMCEIIALSDNQF----SIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPL----IDGGPHKVHIMGS-GVERGLANDANQFTIYTREAGAGSLSIAIEGPS-KAEI-DFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQ---YSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNC-----QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 +++ + V + P + G V+V ND H F P+ + +A++ Y N T D V+A +G V+AI+ +P + +D G +S Y G H +++ + +P+ SP+ + +G + + +G G+ EGI K ++D E + L + P+D ++++ + +Y P Q P +V +K + I V SK++ +G GLE G V P F V+ + GE+ ++ +K+ Q P + L +Y P G ++ VL + + SPFV V + +P VT G+ + + + K+P F ++TR G DL ++ + P ++ G F D P + + V +VPG+PF V V + I +GP+ ++ P T ++ AG G + G V + + + G TV Y Q+ GAY++ ++F E I PN + + E ++ +H +R ++ + P ++ + R +VP IN DGT + E G H+L++ ++ P+ + + + + + AYGPGL A F + AG G LS+ + GP+KAE + D NG C V Y+ APGDY + IKF +H+ GSPF A + K SQI + R+++ D + + + T + L+ + +S +P H V + SG+ + P +I +I +K+ D D + + D R+ G + + GP E H +G V++ G Y + V P G + E I+ H + AE S V N I ++ A + + + + I L DN I F +LG +T+ V HV ++ +G L I KV + V++ QF + L + P+ K E+ + DN DG+ V Y G + SI N + G+P +D + D + ++ Q +G A F + G +S + P+ K Q+ KI +N+ S +VP G + VHV + + SPFRV+V H G +E + + ++ +I P ++ C G +FT P G++ I++K G + +PF + + TQ G + V+ G G + NE +VD AG L V V GP + E+ K + + +V Y E G + + +++ +H V SP + Sbjct: 311 VEDKENAYKVKFTPTKIGFIHVDVAANDVHT----FETQTIPEASVICQVVPIARLLDY----NKTAKVGDDVKFAVVDAI------EGPVEAIVVDPTGKEHRMVILDGTSPGEHSFEYKIPCIGLHSVNVFHKKLPLTGSPFPL---RGKPKNSFKVWGRGIAPEGIRKNDVVGVHVESLDPEENIANANISLEVLKPSDGSHLPVSVGYNDESQSMDFEYSPKQAPDDLEVLVKVAGEVIESHKIHVAPE---SSSKIRAFGAGLE--GGIVNEPCVFDVEMN--GESKDLSFAVEGPSKAEIGCQERPDGSAIL---SYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVT--GIDESKVYNVGEKIP--FRVDTRLCG-VDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGVDGPVYSKEPTRFT----IDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEISPIEINVKPNVDVSGIRVEGLENENLLIGSH----------LRPTINIGKLE----PKSKGLQLIDEVNGKRYNVPMKINP-DGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVIKGTDV--NKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKA-VVDYKKDPSQITISGLDQPNYRLNQPINFVIDTSKTKDLPVKATVPSDFAQLQPV------VSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPFDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEVAARVPVMAEKIGRKEDVIKEEIVFHPEIAEHSP--TVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYE-AIGKLEYERIQAERAKVVVEKEDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDA----------------YGDG-WATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPA-KSQI----KIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRS---HLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFT--PREAGEHLITVKRDG-KLVPKAPFKIKVD-------------------------KTQVGDAS--KVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKA--ELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTV 1695 HSP 7 Score: 135.961 bits (341), Expect = 3.271e-31 Identity = 130/546 (23.81%), Postives = 238/546 (43.59%), Query Frame = 2 Query: 926 KTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNV-KNAAGDPSKVTASG----PGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIE--YTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDV-AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES---KIKAFGPGLTGGIVSKPAFFEV-ETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDG-TYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 K + RV G G + ++G+ + + + + +P G +EPC + L S+ P GE+ I +K +P +PFK+ V K GD SKV SG GI NE V T++AG G + + + K ++T + LI+ YT E G++++ + FA ++ SP V + K++ + + ++ G+ + D + + + D+ + P + +++ + Y+ + P+ G + + + Y + ++ SPF V + E K++A G G+ G F + GA+ +I+GPS+A ++ D+ DG+ +V Y PGEY V + +D++IP SP+ I T L++ + GI K F V T A ++A+ + + I DG +Y+ R+ PK G H + V+ + ESPF++ V + + I G G+ + T + FV++ AG+G + + + Sbjct: 1508 KDSPFRVLVMGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLG--VSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANE------LLVDTSKAGYGGLSVSV------QGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSA---GRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHG---QGIPAGKAFTFTVLTHRA--KGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQM 2031 HSP 8 Score: 132.494 bits (332), Expect = 2.913e-30 Identity = 196/870 (22.53%), Postives = 328/870 (37.70%), Query Frame = 2 Query: 1304 FNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVE---TNGETGALGFSIKGPSEAKIDCVDN--GDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLD-TKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAG---------SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI---ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFV-AGFTPTVIGPHTVTVECKGNPIGNSPYKVI---ATDRVNTKEYPE------------TETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNF--------EPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTI---------YPDTKSSSNID------------------DVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSY 3706 FNV P ++ +++ +K+ + I + L++YT K G H +++ G Q+Q +P V + +AT G + V + A F V + + +L V++ GP +S K K C +++P PG Y V +K G + SPF V V G G +S + EV T E + SIK P + C G V++ P GE+ + + D + +PK+P+ +I++D T++ D KV G G GI T + + +V+T AG PS + C +V G YTP PG + + + + + ++ +SP V I+ +E+ + E++ + DI ++D K + D G + +T+ + + +A + SPF+ + S ++ +K+ G+ F + + V S+ ++ ++ N+G + G + V V+ I +SP+KV AT V E + T T L A ++ K P+ V + + P+E K+ N P E + + R K ++A G+GLVKG F+I++ L V ++GP +A +D + G V Y P PGSY +V YN H SPF + + Y +T S ID D AKVTA G GLN F + F ++ G ++ + V + G Y CSY Sbjct: 1356 FNVRDLGYQPKDLEAIVMPPTQKKEVAE--IIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGD------GWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTC--SAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLV----------MGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPF--KIKVDKTQVGDASKVEVSGSGKAKGI-TLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEV------------KSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQ-QYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHGQGIPAGKAFTFTVLTHRAKGHLEAKVVT-PNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRL-RVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNET-SHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNK--FFPGRPAAFQIDT---GLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSY 2180 HSP 9 Score: 122.865 bits (307), Expect = 2.759e-27 Identity = 201/876 (22.95%), Postives = 346/876 (39.50%), Query Frame = 2 Query: 953 YGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVD--CVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG--------------------ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFD---PLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTG-QTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEA-GNAANIKV---YGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINN-----LNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLG---VTIEGPM-EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNV 3463 YGPGL+ +G PA FTV + L + + P K +I D NK+ S +++P + GEY++ +K + +SPF+V V S ++ V + ++ + + PG ++ C + G + + +T +E G H + V G + +PF + V KT DA + +G G + +G+ ++ E V T AG+ L V+V GP ++ C K+V L + Y P PG Y + IK+ ++ + SP V G + G V + +VE +G + A KG ++ I+ D G + + P + G + + ++ D ++ SP+ Q F KV A G G++ G T F + + AG V A + G ++ +D+NDG Y PG++ V V + + +IP+SPFKV + A G +++ +G GI K T+ V+ + G + + + ++ + +V + DG + I + A + +SPF++ + + I+ + TT GQ EF I T G+ + + V+ S+ + E G+ +TP G + +V+ G SP+K+ V KE + YN+ S K+ V +++ T + + P + + VTA G GL K PA+F ID+ L VT +GP E + + +G CS + G V + Y D+ I SPF + Sbjct: 1435 YGPGLQ--NAVVGEPATFTVCAKGSQAKELSVSIEGP--AKSQIKIHD--NKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVG--STSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDG--------------GRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKV-DKTQVGDASKVEVSGSG-KAKGITLQ-ANELLVDTSKAGYGGLSVSVQGPSKAELTC--KEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCT------------GKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTD-DIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPF----QFTVGSFSEGGAHKVRAAGQGVVRG-ETGTFNAFNIYHREAG----VGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHGQGIPAGKAF--TFTVLTHRAKGHLEAKVVTPNNEVDTIDIVPIE--DGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTT--GQKCEFVINTANAGAGI---LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKI----PVEGKE---------------LGGNGYNETS----HVKIDAVAKTSKGTVA---------------VVPEYQGD------AAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKG--FVFIKYGDKEIPGSPFAI 2206 HSP 10 Score: 105.916 bits (263), Expect = 3.849e-22 Identity = 90/370 (24.32%), Postives = 162/370 (43.78%), Query Frame = 2 Query: 1424 IEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGF--ADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 I +T + G ++++VF+ G + + + + A++A + + + +FQ + D G+ DL V P + E +I Y P+ G + + I + +P V Y + +GPGL +V +PA F V G + L SI+GP++++I DN DG+ + + P VPGEY VH+ + + SP+ + + + L V ST++ A I + G +++K+ G P +R + G +TP+ G+H + V +P++PFK+ V + G+A+ ++V G G + T +VD AG G + +SV Sbjct: 1293 IVFTATKLGTNTLDVFYGGEHVDHVEYEAIGKLEYERIQAERAKVVVEK-EDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGDGWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVG----------STSEVALPITQQELKGISASIKSPG----GIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSV 1647 HSP 11 Score: 103.219 bits (256), Expect = 2.287e-21 Identity = 125/476 (26.26%), Postives = 198/476 (41.60%), Query Frame = 2 Query: 986 IGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSC----------SYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIE-PVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES-----------KIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILC----DDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGIST-----NKPADFIVNT-KNAGSPSTVKAECFDVTGQTIPVQIRD-NNDGTYSCRYTP 2311 +G PF VDT G + L PK EI D ++Y + IP +++I + A +P +PF V VK D SK+ GPG++ PV ++ T F + +AGPG+V+ + D +G ++V + + F ++YT + G + +NV FAG +I SP + V S G+RV + + + + P +S I +V+ Y G Y D H D P KE+ K KA+GPGL +V + A FE++ +G GAL ++GP++A+ D G+G +V Y PG+Y + I E++ SP+ A + DP ++T ISG+ N+P +F+++T K P VKA Q PV R +N ++ R+ P Sbjct: 659 VGEKIPFRVDTRLCG------VDLVPK-----VEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPT-DASKLKIFGPGVDGPVYSK--EPTRFTIDATQAGPGAVEVALRDDQG--ENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNVDVS---------------GIRVEGLENENLLIGSHLRPTINIGKLEP-KSKGLQLIDEVNGKRYNVPMKINPDGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVIKGTDVNKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKK---DPSQIT------ISGLDQPNYRLNQPINFVIDTSKTKDLP--VKATVPSDFAQLQPVVSRSPSNPRHHNVRFVP 1089 HSP 12 Score: 73.559 bits (179), Expect = 2.227e-12 Identity = 111/492 (22.56%), Postives = 215/492 (43.70%), Query Frame = 2 Query: 929 TNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNE---VGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNP----IHLSPFNVDVAPYKE--SKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSE-AKIDCVDNGDGS----ANVTYWP------TVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDN-NDGTYSCRYTPKIPGKHTVI 2338 T++ +++ +GPG++ + P FT+D AG G +++ + + +G+ ++ D N++ +++ Y G Y++ + FA EI SP ++NVK V SG +E + NE +G + + P S ++D G++ +V KI + + + E G H + + F + ++ + V+ +D + A G G+ E V + A F++ + AG L + + GP ++ + Q + C E Y+ + PG Y + IK+G + + SPF V YK+ S+I G +++P F ++T+ +T L PS+ A++ V + S NV + P ++P E L DE + K + QL L D K + + + S F + ++ G+ +++ F G+ +R +G Y + + G++ V+ Sbjct: 738 TDASKLKIFGPGVDGPVYS-KEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLD--NQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVK------PNVDVSGIRVEGLENENLLIGSHLRPTINIGKLEPKSKGLQLIDEVNGKRYNVPMKIN--PDGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVI-----KGTDVNKCKAYGPGL--EQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVE--YVAKAPGDYEMAIKFGKDEQKEHVKGSPFKA-VVDYKKDPSQITISGLDQPNYRLNQPINFVIDTS-KTKDLPVKATVPSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPF--DVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVV 1203 HSP 13 Score: 65.4698 bits (158), Expect = 6.196e-10 Identity = 82/310 (26.45%), Postives = 128/310 (41.29%), Query Frame = 2 Query: 974 EGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNA-AGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSK---------TSNSDAKQAYATGRGI-------QPEGVRVRDV------------AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSY-IPQRPGPYVVDIKYGNNPIHLSPFNVD 1813 +G G FTV T A KG+L+ V+ P + + +I + E +Y+ ++P G + I + + + SPF++ V DP+ ++ASG G+ V G++ F + TA AG G IL + S + E + + YT G + +V + G+ SPF + V K TS+ T +G Q + +V A FQ+ T AG L V V E+ ++ Y CSY IP R +V IKYG+ I SPF ++ Sbjct: 1908 QGIPAGKAFTFTVLTHRA-KGHLEAKVVTPNNEVDTIDIVPIEDGE-SYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGL--VKGTTGQKCEFVINTANAGAG-----ILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVF-IKYGDKEIPGSPFAIE 2207
BLAST of Filamin vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09]) HSP 1 Score: 746.117 bits (1925), Expect = 0.000e+0 Identity = 489/1511 (32.36%), Postives = 767/1511 (50.76%), Query Frame = 2 Query: 3251 ANTPASFIIDSTEEPPAPLGVTIEGPM--EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKF----NEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEI--EVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVR------------PHRGHLIANKVPSLFTINTRDAGE-SDLELMVTGPN-NESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSE-------AKPEQCYIEGPILNEVPVGKTVTIPVNTQNA----GDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPV---GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKI-DNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX--------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSN----------DSIRET-KSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 + P F ID+T+ P + V + +D +DN DG+ +V Y + PG+Y +NV++ E I SP + + P+ DV+ + GL + S + T+N ++ KG+ +I +R + N DGTYS G+HK+ + +D +PV ++ V V +G+D ++ +AYGPGLE+ + + F +DL+GAG+G L + + GPA A+ + D +G CSV+Y+ + PG Y+++IKF ++H+ GSPF + D S++ GL++ R+ P F +D SK + P+K V + ++P S P +V ++P N I E++Y+ +++ + VL EP+ + + + + H GH VP + RD G +E V GP+ E +N +G + + D+ G Y V + V VPV +E E+ I P T P++ + +L+AK + ++N + + K+G + + + E++ + + A E I+ E+ + + E +KF V G + A+V P+ +K+V +I+N DGTI V+Y P G HEL + NG + G+P KFYVD+ G T YGPGL A FT+ K + A LS+++EGP+K++I+ DNK+GTC +++P PG+Y + +K K + SPF + GE +KRS + VG+TS+V L I++ ++ ++A + SP G EE C ++ L G LG+SFTP+E GEHL+ V R G+ +P +PFKI V + ++G+AS+V++ G G G+ + + +VDT AGYGGLS+S++GPSK E+ C + G V Y PTEPG Y I +K+AD +V SP V G + + + I + + + L L + + + TA ++ P G + E+ L + ++F PK G+HT+SV + HV GSPFQFTVG +GG HKV G GV RG N F IY REAG G++++ IEGPSKA ++F+D+ DG+C V Y+V PG+YV ++KFND+H+P SPF + Y P E R + +A QG G F + H G + A V++P+N+ I I D Y++ FVP E G H +HV ++ +P+ SPFR+ V ++ SG+G+ G TG+ EF ++T+NAG G LTV +DGPSK L+ E E GY Y P APG Y S+KY G H GSPF + + G N D++ +T K V G K V +G GL G+ F +D GLAG ++L VGV PCEEV ++H G+ + +Y + ++ + + +++G+ ++PGSPF I Sbjct: 754 SKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNV-------DVSGIRV--EGLENENLLIGSHLRPTINIGKLEPKSKGL--QLIDEVNGKRYNVPMKINPDGTYSTDTPLMEVGEHKLQLLFDEIPVKEA--VVEVIKGTDVNKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKKDPSQITI--SGLDQPNYRLNQPINFVIDTSKTKDLPVKATV-PSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEK--LVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGH-----VP----FDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEVAAR---VPVMAEKIGRKEDVIKEEIVFHPEIAEHSPTVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDH--VEYEAIGKLEYERIQAERAKVVVEKEDDVDKYEKQ---YKFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDA-YGDGWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKV---------YIAPATGE------VRKLELAQFHGQGIPAGKAFTFTVLTH-RAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNG-IHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAK-------VTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFAI 2202 HSP 2 Score: 456.062 bits (1172), Expect = 2.234e-129 Identity = 357/1116 (31.99%), Postives = 535/1116 (47.94%), Query Frame = 2 Query: 191 EDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIK------FANSEIPNSPFKVNVKNAAG--DPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDS-VKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHT----EDAGFADLGVNVYGP--GRSLEKCQIKKVSPCLYECSYIP-QRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDP--LKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE-TYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLY----NDEHIKDSPFNVTI 3469 +DA+WK+IQ+NTFTRW HL+ + I+ L+ D +DGLKLI L Q LS N +K+ FR+QKLENV++ L F + E ++++NIDS+ I D KLILGL+WTLILHYSI+M W E ++DG K +PKQ+LL WI +++P P+ NFT+DWNDG A+GALV++ APG +W W P AL+N ++A+ +A++ L VAPLI P EMI+P++DE ++MTYLSQFP + P + T S + + +P F + G + + + GQ + +KE AY + PT G + + F IP + V A D +K +VG F V A GP V+ +++D G++ V T E+ F EY GLHSVNVF + + SPF + K S GRGI PEG+R DV V + E+ A++ + V P G L + Y P Q P V +K I + VAP SKI+AFG GL GGIV++P F+VE NGE+ L F+++GPS+A+I C + DGSA ++Y PTV G Y V +L D ++I SP++ ++ + P +VT + + P F V+T+ G K E D I R+ G + P P KH + VS V++P +PF V V E +A+ +K++GPG++ + E T F +D AG G + +++ D++ +V + DN DG+FT+KYT + G +F E EI SP ++ ++ + D ++ L NE ++ GS +RP I + ++L + NG V K NP G T+TPL+ ++ + +++ IPV+ A + ++ ++V NK + AYG GL + V A F +D L + + GP +A+ D G+G CSV Y+ K PG Y + + + EH+K SPF + Sbjct: 20 DDAEWKIIQQNTFTRWVKNHLQKAGETIESLETDFSDGLKLIALAQVLSHKNVGKFNKKVAFRSQKLENVSLALNFFQNEENIKIINIDSTHIVDHNKKLILGLVWTLILHYSISMG-WIQE--KREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQFPATKPIIMKPKVQATISNLDKIL---------QVNDPREFDLKLSRDG-FKPKVSIRDEDGQDIHLSLKKVEDKENAYKVKFTPTKIGFIHVDVAANDVHTFETQTIPEASVICQVVPIARLLDYNKTA-----------KVGDDVKFAVVDAIEGP--VEAIVVDPTGKEHRMVILDGTSPGEHSF--EYKIPCIGLHSVNVFHKKLPLTGSPFPLRGKPKNSFK------VWGRGIAPEGIRKNDVVGVHVESLDPEENIANANISLEVLKPSDGSHLPVSVGYNDESQSMDFEYSPKQAPDDLEVLVKVAGEVI--ESHKIHVAPESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIP--FRVDTRLCGVDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGVDGPVYSKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGE-EI--SPIEINVKPNVDVSGIRVEGLE--------NENLLI----GSHLRPTINIGKLEPKSKGLQLIDEVNG------------KRYNVPMKINPDGTY----------------STDTPLMEVGEHKL-QLLFDE--IPVKEAVVEVIKGTDV------NKCK----------------------------AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV 1017 HSP 3 Score: 275.404 bits (703), Expect = 1.157e-73 Identity = 325/1353 (24.02%), Postives = 575/1353 (42.50%), Query Frame = 2 Query: 3809 SRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA---GEA-PLKVNVIDTATKSVKPAQIL-----PKS------TPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNT---QNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHY-TTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFY----NGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSK-AEIQCIDNKNGT----CDVSYLPLAPGDYHIGIKF------MDKHIIG-----SPFTAKIFGEPKKRSQICVGTTSD------VPLRISET-DINNLNAIVISPTGREESCTLKRL-QNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGD--GLNDGMVNETCQF-----------------VVDTRNAGYGGLSLSIEGPSKVEIE-----CHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPF-AVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPF-MLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXX--------XXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 S+IRA+G GLE GI +P F V++ G + L ++EGP+ A+I C + DG+ + Y P G Y V + + KHI SPF + + + ++ GL+ + +RV +D SK GE P +V+ V +IL P S TPGLF+ T IP+ +I+V + VPG+PF V + K+ + G GV + +K P+ FTI+ AG +E+ + E+V+LDV ++ DG+FT +Y PG Y + V++ + + SP + V +EG + +G + +N + G+ V VP I + G + ++G +++QL+F++ IP +++ + + + + + EQ+ + E +V + G + + P+ + R+ + G+G +V+Y G +E+ + + + + GSPFK VD Q+T G R + +F I T + L + PS A++Q + +++ + +V ++P + I I+ +D+ ++ P KI + KK S T++ VP + + ++ + + V P G+E ++ QNG +SF GE+ V +G+ + A+RV + + G + ++ E F + + + + + P V +E + H + + T+ GT ++V Y +V + A+ Y + + +V + + N+ GY ++ A V+ P+ E+ EII D +++ PK G H +S+ + + G+P +F V DG + G G++ + + FT+ + + A LS++IEGP+K++I DNKDG+C + PG+Y +K + V SPF +L + E S+ ++GS + + ISA + SP E+ + +D + V F P E G H + V + +P +PF++ +V VSG G G T + NE VDTS AG G L+V++ GPSK +L C+E +SG Y P PG Y I+IK+ ++H+ SP V +G KS + + I QK +V+ G L E + F+ + D+ + P +++ ++ LG +Q+ + + +G H L V + + V GSPF+ V Sbjct: 547 SKIRAFGAGLEGGIVNEPCVFDVEMNGESKD-LSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIE---------GLKPSATRVTG-----IDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGV----DGPVYSKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNVDVSGIRVEGLENENLLIGSHLRPTINIGKLEPKSKGLQLIDEVNGKRYNVPMKINPD--GTYSTDTPLMEVGEHKLQLLFDE--IP---VKEAVVEVIKGTDVNKCKAYGPGLEQA---VVGEKAVFELDLD-GAGEGALSMEMRGPAKAES--RIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKKDPSQITISGLDQPNYRLNQPINFVIDT--SKTKDLPVKATVPSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPFDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEV----------------AARVPVMAEKIGRKEDVIKEEIVFHPEIAEHSPTVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYEAIGKLEYERIQAERAKVVVEKEDDVDKYEKQYKFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGDGW---ATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSH--------------------------LSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKF-ADHHVKDSPLTVQCTG------------KSAGRVIQTI----QK------DVEQHGICLPDQE---SHLFLKLLNTSPMDIT-ARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTV 1791 HSP 4 Score: 210.69 bits (535), Expect = 6.115e-54 Identity = 223/883 (25.25%), Postives = 379/883 (42.92%), Query Frame = 2 Query: 1964 DCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTG-QTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNG-----------DGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDN--DFKKYKINNLNNTTPIG-QLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFV-AGFTPTVIGPHTVTVECKGNPIGNSPY----------KVIATDRVNTKEY----PETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQ--RSNFEPNEEIIYPVQRTNEKAELR---------------KPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDG-TYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIH-----------------DIV----------------DVSKVKCYGPGLERNGSRVF--TPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTY-IPENIGNCEIEVLYNNMQVPGSPF 4354 + +DN DG+ V Y P V G + + IL + + +P I+ + T YGPGL + + +PA F V K S K + G ++I DN DGT S + P +PG++ V V G + +SPF+V V+ G G +R+ ++ + ++ + + ++++ + G DG + I + +P++PFK+ ++ D K +++ I Q NE + T G + V+ P S+ + +E +G + +TPT G + + ++ + + +SP +VI T + + +++ P+ E+ L + K N + + + + P ++ + +Q + F P E I+ + + A + V A G+G+V+G T +F I E + VTIEGP +A +++ D+ DG C V+Y PG Y+V V +ND+HI DSPF V I P T + + +G G+ P G +F+ FTV + KG ++A + P N+ T + DG +Y+ + P G H I +T DG P+ +SP+ + V DP+ I A G GL +G T Q +F ++ AG G L + ++GP+ A + ++ + G V+Y P PGSY S+K+N H PGSPF +P+ D V D +KV G GL ++ F P+ F +D AG L V V+ TK ++ G + +Y IP+ + + + Y + ++PGSPF Sbjct: 1379 EIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTP----IKFYVDAYGDGWATVYGPGLQNAV-VGEPATFTVCAKG----SQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM-----------GEGQKRSHLSV----------GSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGL-SVSVQGP--SKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFL--------KLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPAT---GEVRKLELAQFHGQGI-PAG---KAFT-FTV----LTHRAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGL----NKFFPGRPAAFQIDTGLAGTNLLMVGVV--TTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGF-VFIKYGDKEIPGSPF 2200 HSP 5 Score: 203.756 bits (517), Expect = 8.252e-52 Identity = 234/854 (27.40%), Postives = 345/854 (40.40%), Query Frame = 2 Query: 3218 TAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----GEAPLKVNVIDTATKSVKPAQILPKSTPG----------LFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCE--PEKVIVTGEG-VRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPF---IVPVHSEA-KPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGP-----VGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQ-PSESGL--HELE------------------VFYNGQPITGSPFKFYVD----------------------------STIP-----SGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAV---EGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFT 5524 T YG GL V PA+F + + L V+IEGP +++I DN DGTCS ++P PG Y V+V + +KDSPF V + + + S++ S + A PI + A I +P C V G S++P G+H I + DG V K+P+ + V Q D S++ G G +GIT Q + VD AG GGL +S++GP+ A++ C + K G V Y P +PG Y ++IKF + H+ SP T V+C G ++ RV Q V+ E+ L + +++T+ + + PK + + + P+ G + V+Y + V GSPF V + E KV G+G VR G A F I R+AG + + + GP+ + L+ +H DG YK PG Y V V + ++++P SPF I P E K E G +P GK T V T A G L AK V P +IVP + E Y + +VP++ G + + + + +R+ F+ + + P T S G V+N N G G +TVQ PS++ L +ELE V YNG GSPFK V+ + +P + +VTA G GL+ P A F I T AG L + V +GP + E+ +G SY + IK+ DK I GSPF Sbjct: 1429 TVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHL---------------------SVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLT-----------VQCTG----KSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNA------FNIYHREAGVGAVAVTIEGPSKAT--LEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHG---QGIPAGKAFTFTVLTHRA-KGHLEAKVVTPNNEVDTIDIVPIE-DGESYA---MRFVPKETGNHFIHVTLD-----GAPMRESPFRLRVG----------GKDLCDP---TAISASGDGLVKGTTGQKCEFVINTA----------NAGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCE-EVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFA 2201 HSP 6 Score: 171.014 bits (432), Expect = 7.653e-42 Identity = 332/1506 (22.05%), Postives = 570/1506 (37.85%), Query Frame = 2 Query: 3350 IDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPF-NQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP----QKFTVD-LEGAGQGGLGLSIEGPADAQ----IQCFDNKDGTCSVQYLP-QKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNV---LNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDL--ELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYI-----EGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENI--------PNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKF----MDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISE-----TDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNA----------SRVKLYGDGLNDGM--------VNETCQFVVDTRNAG-YGGLSLSIEGPSKVEIECH---DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGS-PFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTA--SVISPSGSFEMCEIIALSDNQF----SIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPL----IDGGPHKVHIMGSGVERGLANDANQFTIYTREAG--AGSLSIAIEGPS-KAEI-DFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQ---YSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNC-----QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 +++ + V + P + G V+V ND H F P+ + +A++ Y N T D V+A +G V+AI+ +P + +D G +S Y G H +++ + +P+ SP+ + +G + + +G G+ EGI K ++D E + L + P+D ++++ + +Y P Q P +V +K + I V SK++ +G GLE G V P F V+ + GE+ ++ +K+ Q P + L +Y P G ++ VL + + SPFV V + +P VT G+ + + + K+P F ++TR G DL ++ + P ++ G F D P + + V +VPG+PF V V + I +GP+ ++ P T ++ AG G + G V + + + G TV Y Q+ GAY++ ++F E I PN + + E ++ +H +R ++ + P ++ + R +VP IN DGT + E G H+L++ ++ P+ + + + + + AYGPGL A F + AG G LS+ + GP+KAE + D NG C V Y+ APGDY + IKF +H+ GSPF A + K SQI + R+++ D + + + T + L+ + +S +P H V + SG+ + P +I +I +K+ D D + + D R+ G + + GP E H +G V++ G Y + V P G + E I+ H + AE S V N I ++ A + + + + I L DN I F +LG +T+ V HV ++ +G L I KV + E + Q+ R+ G L + P+ K E+ + DN DG+ V Y G + SI N + G+P +D + D + ++ Q +G A F + G +S + P+ K Q+ KI +N+ S +VP G + VHV + + SPFRV+V H G +E + + ++ +I P ++ C G +FT P G++ I++K G + +PF + + TQ G + V+ G G + NE +VD AG L V V GP + E+ K + + +V Y E G + + +++ +H V SP + Sbjct: 309 VEDKENAYKVKFTPTKIGFIHVDVAANDVHT----FETQTIPEASVICQVVPIARLLDY----NKTAKVGDDVKFAVVDAI------EGPVEAIVVDPTGKEHRMVILDGTSPGEHSFEYKIPCIGLHSVNVFHKKLPLTGSPFPL---RGKPKNSFKVWGRGIAPEGIRKNDVVGVHVESLDPEENIANANISLEVLKPSDGSHLPVSVGYNDESQSMDFEYSPKQAPDDLEVLVKVAGEVIESHKIHVAPE---SSSKIRAFGAGLE--GGIVNEPCVFDVEMN--GESKDLSFAVEGPSKAEIGCQERPDGSAIL---SYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVT--GIDESKVYNVGEKIP--FRVDTRLCG-VDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGVDGPVYSKEPTRFT----IDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEISPIEINVKPNVDVSGIRVEGLENENLLIGSH----------LRPTINIGKLE----PKSKGLQLIDEVNGKRYNVPMKINP-DGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVIKGTDV--NKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKA-VVDYKKDPSQITISGLDQPNYRLNQPINFVIDTSKTKDLPVKATVPSDFAQLQPV------VSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPFDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEVAARVPVMAEKIGRKEDVIKEEIVFHPEIAEHSP--TVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYE-AIGKLEYERIQAERAKVVVEK---EDDVDKYEKQYKFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDA----------------YGDG-WATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPA-KSQI----KIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRS---HLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFT--PREAGEHLITVKRDG-KLVPKAPFKIKVD-------------------------KTQVGDAS--KVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKA--ELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTV 1691 HSP 7 Score: 135.961 bits (341), Expect = 2.693e-31 Identity = 130/546 (23.81%), Postives = 238/546 (43.59%), Query Frame = 2 Query: 926 KTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNV-KNAAGDPSKVTASG----PGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIE--YTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDV-AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES---KIKAFGPGLTGGIVSKPAFFEV-ETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDG-TYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 K + RV G G + ++G+ + + + + +P G +EPC + L S+ P GE+ I +K +P +PFK+ V K GD SKV SG GI NE V T++AG G + + + K ++T + LI+ YT E G++++ + FA ++ SP V + K++ + + ++ G+ + D + + + D+ + P + +++ + Y+ + P+ G + + + Y + ++ SPF V + E K++A G G+ G F + GA+ +I+GPS+A ++ D+ DG+ +V Y PGEY V + +D++IP SP+ I T L++ + GI K F V T A ++A+ + + I DG +Y+ R+ PK G H + V+ + ESPF++ V + + I G G+ + T + FV++ AG+G + + + Sbjct: 1504 KDSPFRVLVMGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLG--VSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANE------LLVDTSKAGYGGLSVSV------QGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSA---GRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHG---QGIPAGKAFTFTVLTHRA--KGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQM 2027 HSP 8 Score: 133.265 bits (334), Expect = 1.977e-30 Identity = 196/877 (22.35%), Postives = 330/877 (37.63%), Query Frame = 2 Query: 1304 FNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVE---TNGETGALGFSIKGPSEAKIDCVDN--GDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLD-TKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAG---------SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI---ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFV-AGFTPTVIGPHTVTVECKGNPIGNSPYKVI---ATDRVNTKEYPE------------TETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKP---------------NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTI---------YPDTKSSSNID------------------DVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSY 3706 FNV P ++ +++ +K+ + I + L++YT K G H +++ G Q+Q +P V + +AT G + V + A F V + + +L V++ GP +S K K C +++P PG Y V +K G + SPF V V G G +S + EV T E + SIK P + C G V++ P GE+ + + D + +PK+P+ +I++D T++ D KV G G GI T + + +V+T AG PS + C +V G YTP PG + + + + + ++ +SP V I+ +E+ + E++ + DI ++D K + D G + +T+ + + +A + SPF+ + S ++ +K+ G+ F + + V S+ ++ ++ N+G + G + V V+ I +SP+KV AT V E + T T L A ++ K P+ V + + P+E F P E + + T + A +R+ ++A G+GLVKG F+I++ L V ++GP +A +D + G V Y P PGSY +V YN H SPF + + Y +T S ID D AKVTA G GLN F + F ++ G ++ + V + G Y CSY Sbjct: 1352 FNVRDLGYQPKDLEAIVMPPTQKKEVAE--IIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGD------GWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTC--SAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLV----------MGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPF--KIKVDKTQVGDASKVEVSGSGKAKGI-TLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEV------------KSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQ-QYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHGQGIPAGKAFTFTVLTHRAKGHLEAKVVT-PNNEVDTIDIVPIEDGESYAM--------RFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNET-SHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNK--FFPGRPAAFQIDT---GLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSY 2176 HSP 9 Score: 123.25 bits (308), Expect = 1.857e-27 Identity = 201/876 (22.95%), Postives = 347/876 (39.61%), Query Frame = 2 Query: 953 YGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVD--CVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG--------------------ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFD---PLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQT-IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEA-GNAANIKV---YGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINN-----LNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLG---VTIEGPM-EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNV 3463 YGPGL+ +G PA FTV + L + + P K +I D NK+ S +++P + GEY++ +K + +SPF+V V S ++ V + ++ + + PG ++ C + G + + +T +E G H + V G + +PF + V KT DA + +G G + +G+ ++ E V T AG+ L V+V GP ++ C K+V L + Y P PG Y + IK+ ++ + SP V G + G V + +VE +G + A KG ++ I+ D G + + P + G + + ++ D ++ SP+ Q F KV A G G++ G T F + + AG V A + G + ++ +D+NDG Y PG++ V V + + +IP+SPFKV + A G +++ +G GI K T+ V+ + G + + + ++ + +V + DG + I + A + +SPF++ + + I+ + TT GQ EF I T G+ + + V+ S+ + E G+ +TP G + +V+ G SP+K+ V KE + YN+ S K+ V +++ T + + P + + VTA G GL K PA+F ID+ L VT +GP E + + +G CS + G V + Y D+ I SPF + Sbjct: 1431 YGPGLQ--NAVVGEPATFTVCAKGSQAKELSVSIEGP--AKSQIKIHD--NKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVG--STSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDG--------------GRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKV-DKTQVGDASKVEVSGSG-KAKGITLQ-ANELLVDTSKAGYGGLSVSVQGPSKAELTC--KEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCT------------GKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTD-DIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPF----QFTVGSFSEGGAHKVRAAGQGVVRG-ETGTFNAFNIYHREAG----VGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHGQGIPAGKAF--TFTVLTHRAKGHLEAKVVTPNNEVDTIDIVPIE--DGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTT--GQKCEFVINTANAGAGI---LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKI----PVEGKE---------------LGGNGYNETS----HVKIDAVAKTSKGTVA---------------VVPEYQGD------AAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKG--FVFIKYGDKEIPGSPFAI 2202 HSP 10 Score: 105.531 bits (262), Expect = 4.438e-22 Identity = 89/370 (24.05%), Postives = 163/370 (44.05%), Query Frame = 2 Query: 1424 IEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGF--ADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 I +T + G ++++VF+ G + + + + A++A ++ E + +++ + D G+ DL V P + E +I Y P+ G + + I + +P V Y + +GPGL +V +PA F V G + L SI+GP++++I DN DG+ + + P VPGEY VH+ + + SP+ + + + L V ST++ A I + G +++K+ G P +R + G +TP+ G+H + V +P++PFK+ V + G+A+ ++V G G + T +VD AG G + +SV Sbjct: 1291 IVFTATKLGTNTLDVFYGGEHVDHVEYEAIGKLEYERIQAERAKVV---VEKEDDVDKYEKQYKFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGDGWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVG----------STSEVALPITQQELKGISASIKSPG----GIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSV 1643 HSP 11 Score: 103.605 bits (257), Expect = 1.791e-21 Identity = 125/476 (26.26%), Postives = 198/476 (41.60%), Query Frame = 2 Query: 986 IGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSC----------SYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIE-PVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES-----------KIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILC----DDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGIST-----NKPADFIVNT-KNAGSPSTVKAECFDVTGQTIPVQIRD-NNDGTYSCRYTP 2311 +G PF VDT G + L PK EI D ++Y + IP +++I + A +P +PF V VK D SK+ GPG++ PV ++ T F + +AGPG+V+ + D +G ++V + + F ++YT + G + +NV FAG +I SP + V S G+RV + + + + P +S I +V+ Y G Y D H D P KE+ K KA+GPGL +V + A FE++ +G GAL ++GP++A+ D G+G +V Y PG+Y + I E++ SP+ A + DP ++T ISG+ N+P +F+++T K P VKA Q PV R +N ++ R+ P Sbjct: 657 VGEKIPFRVDTRLCG------VDLVPK-----VEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPT-DASKLKIFGPGVDGPVYSK--EPTRFTIDATQAGPGAVEVALRDDQG--ENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNVDVS---------------GIRVEGLENENLLIGSHLRPTINIGKLEP-KSKGLQLIDEVNGKRYNVPMKINPDGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVIKGTDVNKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKK---DPSQIT------ISGLDQPNYRLNQPINFVIDTSKTKDLP--VKATVPSDFAQLQPVVSRSPSNPRHHNVRFVP 1087 HSP 12 Score: 73.9442 bits (180), Expect = 1.882e-12 Identity = 111/492 (22.56%), Postives = 215/492 (43.70%), Query Frame = 2 Query: 929 TNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNE---VGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNP----IHLSPFNVDVAPYKE--SKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSE-AKIDCVDNGDGS----ANVTYWP------TVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDN-NDGTYSCRYTPKIPGKHTVI 2338 T++ +++ +GPG++ + P FT+D AG G +++ + + +G+ ++ D N++ +++ Y G Y++ + FA EI SP ++NVK V SG +E + NE +G + + P S ++D G++ +V KI + + + E G H + + F + ++ + V+ +D + A G G+ E V + A F++ + AG L + + GP ++ + Q + C E Y+ + PG Y + IK+G + + SPF V YK+ S+I G +++P F ++T+ +T L PS+ A++ V + S NV + P ++P E L DE + K + QL L D K + + + S F + ++ G+ +++ F G+ +R +G Y + + G++ V+ Sbjct: 736 TDASKLKIFGPGVDGPVYS-KEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLD--NQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVK------PNVDVSGIRVEGLENENLLIGSHLRPTINIGKLEPKSKGLQLIDEVNGKRYNVPMKIN--PDGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVI-----KGTDVNKCKAYGPGL--EQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVE--YVAKAPGDYEMAIKFGKDEQKEHVKGSPFKA-VVDYKKDPSQITISGLDQPNYRLNQPINFVIDTS-KTKDLPVKATVPSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPF--DVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVV 1201 HSP 13 Score: 65.855 bits (159), Expect = 5.370e-10 Identity = 82/310 (26.45%), Postives = 128/310 (41.29%), Query Frame = 2 Query: 974 EGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNA-AGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSK---------TSNSDAKQAYATGRGI-------QPEGVRVRDV------------AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSY-IPQRPGPYVVDIKYGNNPIHLSPFNVD 1813 +G G FTV T A KG+L+ V+ P + + +I + E +Y+ ++P G + I + + + SPF++ V DP+ ++ASG G+ V G++ F + TA AG G IL + S + E + + YT G + +V + G+ SPF + V K TS+ T +G Q + +V A FQ+ T AG L V V E+ ++ Y CSY IP R +V IKYG+ I SPF ++ Sbjct: 1904 QGIPAGKAFTFTVLTHRA-KGHLEAKVVTPNNEVDTIDIVPIEDGE-SYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGL--VKGTTGQKCEFVINTANAGAG-----ILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVF-IKYGDKEIPGSPFAIE 2203
BLAST of Filamin vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09]) HSP 1 Score: 745.347 bits (1923), Expect = 0.000e+0 Identity = 489/1511 (32.36%), Postives = 764/1511 (50.56%), Query Frame = 2 Query: 3251 ANTPASFIIDSTEEPPAPLGVTIEGPM--EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKF----NEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEI--EVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVR------------PHRGHLIANKVPSLFTINTRDAGE-SDLELMVTGPN-NESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSE-------AKPEQCYIEGPILNEVPVGKTVTIPVNTQNA----GDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPV---GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKI-DNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX--------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSN----------DSIRET-KSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 + P F ID+T+ P + V + +D +DN DG+ +V Y + PG+Y +NV++ E I SP + + P+ DV+ + GL + S + T+N ++ KG+ +I +R + N DGTYS G+HK+ + +D +PV ++ V V +G+D ++ +AYGPGLE+ + + F +DL+GAG+G L + + GPA A+ + D +G CSV+Y+ + PG Y+++IKF ++H+ GSPF + D S++ GL++ R+ P F +D SK + P+K V + ++P S P +V ++P N I E++Y+ +++ + VL EP+ + + + + H GH VP + RD G +E V GP+ E +N +G + + D+ G Y V + V VPV +E E+ I P T P++ + +L+AK + ++N + + K+G + + + E++ + E+ ER E +Y F+F V G + A+V P+ +K+V +I+N DGTI V+Y P G HEL + NG + G+P KFYVD+ G T YGPGL A FT+ K + A LS+++EGP+K++I+ DNK+GTC +++P PG+Y + +K K + SPF + GE +KRS + VG+TS+V L I++ ++ ++A + SP G EE C ++ L G LG+SFTP+E GEHL+ V R G+ +P +PFKI V + ++G+AS+V++ G G G+ + + +VDT AGYGGLS+S++GPSK E+ C + G V Y PTEPG Y I +K+AD +V SP V G + + + I + + + L L + + + TA ++ P G + E+ L + ++F PK G+HT+SV + HV GSPFQFTVG +GG HKV G GV RG N F IY REAG G++++ IEGPSKA ++F+D+ DG+C V Y+V PG+YV ++KFND+H+P SPF + Y P E R + +A QG G F + H G + A V++P+N+ I I D Y++ FVP E G H +HV ++ +P+ SPFR+ V ++ SG+G+ G TG+ EF ++T+NAG G LTV +DGPSK L+ E E GY Y P APG Y S+KY G H GSPF + + G N D++ +T K V G K V +G GL G+ F +D GLAG ++L VGV PCEEV ++H G+ + +Y + ++ + + +++G+ ++PGSPF I Sbjct: 622 SKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNV-------DVSGIRV--EGLENENLLIGSHLRPTINIGKLEPKSKGL--QLIDEVNGKRYNVPMKINPDGTYSTDTPLMEVGEHKLQLLFDEIPVKEA--VVEVIKGTDVNKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKKDPSQITI--SGLDQPNYRLNQPINFVIDTSKTKDLPVKATV-PSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEK--LVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGH-----VP----FDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEVAAR---VPVMAEKIGRKEDVIKEEIVFHPEIAEHSPTVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYEAIGKLEYERIQAERAKVVVEKEDDVDKYEKQYK---FQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDA-YGDGWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKV---------YIAPATGE------VRKLELAQFHGQGIPAGKAFTFTVLTH-RAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNG-IHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAK-------VTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFAI 2072 HSP 2 Score: 320.472 bits (820), Expect = 1.555e-87 Identity = 293/994 (29.48%), Postives = 449/994 (45.17%), Query Frame = 2 Query: 563 NQQDGQGKGPSPKQRLLGWINSKMP--HKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIK------FANSEIPNSPFKVNVKNAAG--DPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDS-VKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHT----EDAGFADLGVNVYGP--GRSLEKCQIKKVSPCLYECSYIP-QRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDP--LKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE-TYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLY----NDEHIKDSPFNVTI 3469 ++DG K +PKQ+LL WI +++P P+ NFT+DWNDG A+GALV++ APG +W W P AL+N ++A+ +A++ L VAPLI P EMI+P++DE ++MTYLSQFP + P + T S + + +P F + G + + + GQ + +KE AY + PT G + + F IP + V A D +K +VG F V A GP V+ +++D G++ V T E+ F EY GLHSVNVF + + SPF + K S GRGI PEG+R DV V + E+ A++ + V P G L + Y P Q P V +K I + VAP SKI+AFG GL GGIV++P F+VE NGE+ L F+++GPS+A+I C + DGSA ++Y PTV G Y V +L D ++I SP++ ++ + P +VT + + P F V+T+ G K E D I R+ G + P P KH + VS V++P +PF V V E +A+ +K++GPG++ + E T F +D AG G + +++ D++ +V + DN DG+FT+KYT + G +F E EI SP ++ ++ + D ++ L NE ++ GS +RP I + ++L + NG V K NP G T+TPL+ ++ + +++ IPV+ A + ++ ++V NK + AYG GL + V A F +D L + + GP +A+ D G+G CSV Y+ K PG Y + + + EH+K SPF + Sbjct: 7 KREDGDNKEETPKQKLLNWIRNRLPVSGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQFPATKPIIMKPKVQATISNLDKIL---------QVNDPREFDLKLSRDG-FKPKVSIRDEDGQDIHLSLKKVEDKENAYKVKFTPTKIGFIHVDVAANDVHTFETQTIPEASVICQVVPIARLLDYNKTA-----------KVGDDVKFAVVDAIEGP--VEAIVVDPTGKEHRMVILDGTSPGEHSF--EYKIPCIGLHSVNVFHKKLPLTGSPFPLRGKPKNSFK------VWGRGIAPEGIRKNDVVGVHVESLDPEENIANANISLEVLKPSDGSHLPVSVGYNDESQSMDFEYSPKQAPDDLEVLVKVAGEVIE--SHKIHVAPESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIP--FRVDTRLCGVDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGVDGPVYSKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGE-EI--SPIEINVKPNVDVSGIRVEGLE--------NENLLI----GSHLRPTINIGKLEPKSKGLQLIDEVNG------------KRYNVPMKINPDGTY----------------STDTPLMEVGEHKL-QLLFDE--IPVKEAVVEVIKGTDV------NKCK----------------------------AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV 885 HSP 3 Score: 275.404 bits (703), Expect = 1.020e-73 Identity = 325/1359 (23.91%), Postives = 574/1359 (42.24%), Query Frame = 2 Query: 3809 SRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA---GEA-PLKVNVIDTATKSVKPAQIL-----PKS------TPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNT---QNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHY-TTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFY----NGQPITGSPFKFYVDSTIPSGQVTAYG---PGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSK-AEIQCIDNKNGT----CDVSYLPLAPGDYHIGIKF------MDKHIIG-----SPFTAKIFGEPKKRSQICVGTTSD------VPLRISET-DINNLNAIVISPTGREESCTLKRL-QNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGD--GLNDGMVNETCQF-----------------VVDTRNAGYGGLSLSIEGPSKVEIE-----CHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSL-TER---ILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPF-MLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXX--------XXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 S+IRA+G GLE GI +P F V++ G + L ++EGP+ A+I C + DG+ + Y P G Y V + + KHI SPF + + + ++ GL+ + +RV +D SK GE P +V+ V +IL P S TPGLF+ T IP+ +I+V + VPG+PF V + K+ + G GV + +K P+ FTI+ AG +E+ + E+V+LDV ++ DG+FT +Y PG Y + V++ + + SP + V +EG + +G + +N + G+ V VP I + G + ++G +++QL+F++ IP +++ + + + + + EQ+ + E +V + G + + P+ + R+ + G+G +V+Y G +E+ + + + + GSPFK VD Q+T G P +P T TKD L + PS A++Q + +++ + +V ++P + I I+ +D+ ++ P KI + KK S T++ VP + + ++ + + V P G+E ++ QNG +SF GE+ V +G+ + A+RV + + G + ++ E F + + + + + P V +E + H + + T+ GT ++V Y +V + IG + ER ++ +D + + + N+ GY ++ A V+ P+ E+ EII D +++ PK G H +S+ + + G+P +F V DG + G G++ + + FT+ + + A LS++IEGP+K++I DNKDG+C + PG+Y +K + V SPF +L + E S+ ++GS + + ISA + SP E+ + +D + V F P E G H + V + +P +PF++ +V VSG G G T + NE VDTS AG G L+V++ GPSK +L C+E +SG Y P PG Y I+IK+ ++H+ SP V +G KS + + I ++ + C D + N +D + + P +++ ++ LG +Q+ + + +G H L V + + V GSPF+ V Sbjct: 415 SKIRAFGAGLEGGIVNEPCVFDVEMNGESKD-LSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIE---------GLKPSATRVTG-----IDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGV----DGPVYSKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNVDVSGIRVEGLENENLLIGSHLRPTINIGKLEPKSKGLQLIDEVNGKRYNVPMKINPD--GTYSTDTPLMEVGEHKLQLLFDE--IP---VKEAVVEVIKGTDVNKCKAYGPGLEQA---VVGEKAVFELDLD-GAGEGALSMEMRGPAKAES--RIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKKDPSQITISGLDQPNYRLNQPINFVIDTSKTKD-----LPVKATVPSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPFDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEV----------------AARVPVMAEKIGRKEDVIKEEIVFHPEIAEHSPTVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYEA-IGKLEYERIQAERAKVVVEKEDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGDGW---ATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSH--------------------------LSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKF-ADHHVKDSPLTVQCTG------------KSAGRVIQTIQKDVEQ------HGICLPDQESHLFLKLLNTSPMD--------ITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTV 1661 HSP 4 Score: 209.149 bits (531), Expect = 1.457e-53 Identity = 223/883 (25.25%), Postives = 379/883 (42.92%), Query Frame = 2 Query: 1964 DCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTG-QTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNG-----------DGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDN--DFKKYKINNLNNTTPIG-QLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFV-AGFTPTVIGPHTVTVECKGNPIGNSPY----------KVIATDRVNTKEY----PETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQ--RSNFEPNEEIIYPVQRTNEKAELR---------------KPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDG-TYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIH-----------------DIV----------------DVSKVKCYGPGLERNGSRVF--TPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTY-IPENIGNCEIEVLYNNMQVPGSPF 4354 + +DN DG+ V Y P V G + + IL + + +P I+ + T YGPGL + + +PA F V K S K + G ++I DN DGT S + P +PG++ V V G + +SPF+V V+ G G +R+ ++ + ++ + + ++++ + G DG + I + +P++PFK+ ++ D K +++ I Q NE + T G + V+ P S+ + +E +G + +TPT G + + ++ + + +SP +VI T + + +++ P+ E+ L + K N + + + + P ++ + +Q + F P E I+ + + A + V A G+G+V+G T +F I E + VTIEGP +A +++ D+ DG C V+Y PG Y+V V +ND+HI DSPF V I P T + + +G G+ P G +F+ FTV + KG ++A + P N+ T + DG +Y+ + P G H I +T DG P+ +SP+ + V DP+ I A G GL +G T Q +F ++ AG G L + ++GP+ A + ++ + G V+Y P PGSY S+K+N H PGSPF +P+ D V D +KV G GL ++ F P+ F +D AG L V V+ TK ++ G + +Y IP+ + + + Y + ++PGSPF Sbjct: 1249 EIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTP----IKFYVDAYGDGWATVYGPGLQNAV-VGEPATFTVCAKG----SQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM-----------GEGQKRSHLSV----------GSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGL-SVSVQGP--SKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFL--------KLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPAT---GEVRKLELAQFHGQGI-PAG---KAFT-FTV----LTHRAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGL----NKFFPGRPAAFQIDTGLAGTNLLMVGVV--TTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGF-VFIKYGDKEIPGSPF 2070 HSP 5 Score: 202.216 bits (513), Expect = 2.354e-51 Identity = 234/854 (27.40%), Postives = 345/854 (40.40%), Query Frame = 2 Query: 3218 TAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----GEAPLKVNVIDTATKSVKPAQILPKSTPG----------LFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCE--PEKVIVTGEG-VRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPF---IVPVHSEA-KPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGP-----VGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQ-PSESGL--HELE------------------VFYNGQPITGSPFKFYVD----------------------------STIP-----SGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAV---EGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFT 5524 T YG GL V PA+F + + L V+IEGP +++I DN DGTCS ++P PG Y V+V + +KDSPF V + + + S++ S + A PI + A I +P C V G S++P G+H I + DG V K+P+ + V Q D S++ G G +GIT Q + VD AG GGL +S++GP+ A++ C + K G V Y P +PG Y ++IKF + H+ SP T V+C G ++ RV Q V+ E+ L + +++T+ + + PK + + + P+ G + V+Y + V GSPF V + E KV G+G VR G A F I R+AG + + + GP+ + L+ +H DG YK PG Y V V + ++++P SPF I P E K E G +P GK T V T A G L AK V P +IVP + E Y + +VP++ G + + + + +R+ F+ + + P T S G V+N N G G +TVQ PS++ L +ELE V YNG GSPFK V+ + +P + +VTA G GL+ P A F I T AG L + V +GP + E+ +G SY + IK+ DK I GSPF Sbjct: 1299 TVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHL---------------------SVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLT-----------VQCTG----KSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNA------FNIYHREAGVGAVAVTIEGPSKAT--LEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHG---QGIPAGKAFTFTVLTHRA-KGHLEAKVVTPNNEVDTIDIVPIE-DGESYA---MRFVPKETGNHFIHVTLD-----GAPMRESPFRLRVG----------GKDLCDP---TAISASGDGLVKGTTGQKCEFVINTA----------NAGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCE-EVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFA 2071 HSP 6 Score: 168.703 bits (426), Expect = 3.119e-41 Identity = 331/1505 (21.99%), Postives = 569/1505 (37.81%), Query Frame = 2 Query: 3350 IDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPF-NQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP----QKFTVD-LEGAGQGGLGLSIEGPADAQ----IQCFDNKDGTCSVQYLP-QKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNV---LNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDL--ELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYI-----EGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENI--------PNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKF----MDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISE-----TDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNA----------SRVKLYGDGLNDGM--------VNETCQFVVDTRNAG-YGGLSLSIEGPSKVEIECH---DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGS-PFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTA--SVISPSGSFEMCEIIALSDNQF----SIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPL----IDGGPHKVHIMGS-GVERGLANDANQFTIYTREAGAGSLSIAIEGPS-KAEI-DFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQ---YSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNC-----QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 +++ + V + P + G V+V ND H F P+ + +A++ Y N T D V+A +G V+AI+ +P + +D G +S Y G H +++ + +P+ SP+ + +G + + +G G+ EGI K ++D E + L + P+D ++++ + +Y P Q P +V +K + I V SK++ +G GLE G V P F V+ + GE+ ++ +K+ Q P + L +Y P G ++ VL + + SPFV V + +P VT G+ + + + K+P F ++TR G DL ++ + P ++ G F D P + + V +VPG+PF V V + I +GP+ ++ P T ++ AG G + G V + + + G TV Y Q+ GAY++ ++F E I PN + + E ++ +H +R ++ + P ++ + R +VP IN DGT + E G H+L++ ++ P+ + + + + + AYGPGL A F + AG G LS+ + GP+KAE + D NG C V Y+ APGDY + IKF +H+ GSPF A + K SQI + R+++ D + + + T + L+ + +S +P H V + SG+ + P +I +I +K+ D D + + D R+ G + + GP E H +G V++ G Y + V P G + E I+ H + AE S V N I ++ A + + + + I L DN I F +LG +T+ V HV ++ +G L I KV + V++ QF + L + P+ K E+ + DN DG+ V Y G + SI N + G+P +D + D + ++ Q +G A F + G +S + P+ K Q+ KI +N+ S +VP G + VHV + + SPFRV+V H G +E + + ++ +I P ++ C G +FT P G++ I++K G + +PF + + TQ G + V+ G G + NE +VD AG L V V GP + E+ K + + +V Y E G + + +++ +H V SP + Sbjct: 177 VEDKENAYKVKFTPTKIGFIHVDVAANDVHT----FETQTIPEASVICQVVPIARLLDY----NKTAKVGDDVKFAVVDAI------EGPVEAIVVDPTGKEHRMVILDGTSPGEHSFEYKIPCIGLHSVNVFHKKLPLTGSPFPL---RGKPKNSFKVWGRGIAPEGIRKNDVVGVHVESLDPEENIANANISLEVLKPSDGSHLPVSVGYNDESQSMDFEYSPKQAPDDLEVLVKVAGEVIESHKIHVAPE---SSSKIRAFGAGLE--GGIVNEPCVFDVEMN--GESKDLSFAVEGPSKAEIGCQERPDGSAIL---SYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVT--GIDESKVYNVGEKIP--FRVDTRLCG-VDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGVDGPVYSKEPTRFT----IDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEISPIEINVKPNVDVSGIRVEGLENENLLIGSH----------LRPTINIGKLE----PKSKGLQLIDEVNGKRYNVPMKINP-DGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVIKGTDV--NKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKA-VVDYKKDPSQITISGLDQPNYRLNQPINFVIDTSKTKDLPVKATVPSDFAQLQPV------VSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPFDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEVAARVPVMAEKIGRKEDVIKEEIVFHPEIAEHSP--TVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYE-AIGKLEYERIQAERAKVVVEKEDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDA----------------YGDG-WATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPA-KSQI----KIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRS---HLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFT--PREAGEHLITVKRDG-KLVPKAPFKIKVD-------------------------KTQVGDAS--KVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSK--AELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTV 1561 HSP 7 Score: 135.191 bits (339), Expect = 4.940e-31 Identity = 130/546 (23.81%), Postives = 238/546 (43.59%), Query Frame = 2 Query: 926 KTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNV-KNAAGDPSKVTASG----PGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIE--YTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDV-AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES---KIKAFGPGLTGGIVSKPAFFEV-ETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDG-TYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 K + RV G G + ++G+ + + + + +P G +EPC + L S+ P GE+ I +K +P +PFK+ V K GD SKV SG GI NE V T++AG G + + + K ++T + LI+ YT E G++++ + FA ++ SP V + K++ + + ++ G+ + D + + + D+ + P + +++ + Y+ + P+ G + + + Y + ++ SPF V + E K++A G G+ G F + GA+ +I+GPS+A ++ D+ DG+ +V Y PGEY V + +D++IP SP+ I T L++ + GI K F V T A ++A+ + + I DG +Y+ R+ PK G H + V+ + ESPF++ V + + I G G+ + T + FV++ AG+G + + + Sbjct: 1374 KDSPFRVLVMGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLG--VSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANE------LLVDTSKAGYGGLSVSV------QGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSA---GRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHG---QGIPAGKAFTFTVLTHRA--KGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQM 1897 HSP 8 Score: 132.494 bits (332), Expect = 3.066e-30 Identity = 196/870 (22.53%), Postives = 328/870 (37.70%), Query Frame = 2 Query: 1304 FNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVE---TNGETGALGFSIKGPSEAKIDCVDN--GDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLD-TKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAG---------SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI---ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFV-AGFTPTVIGPHTVTVECKGNPIGNSPYKVI---ATDRVNTKEYPE------------TETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNF--------EPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTI---------YPDTKSSSNID------------------DVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSY 3706 FNV P ++ +++ +K+ + I + L++YT K G H +++ G Q+Q +P V + +AT G + V + A F V + + +L V++ GP +S K K C +++P PG Y V +K G + SPF V V G G +S + EV T E + SIK P + C G V++ P GE+ + + D + +PK+P+ +I++D T++ D KV G G GI T + + +V+T AG PS + C +V G YTP PG + + + + + ++ +SP V I+ +E+ + E++ + DI ++D K + D G + +T+ + + +A + SPF+ + S ++ +K+ G+ F + + V S+ ++ ++ N+G + G + V V+ I +SP+KV AT V E + T T L A ++ K P+ V + + P+E K+ N P E + + R K ++A G+GLVKG F+I++ L V ++GP +A +D + G V Y P PGSY +V YN H SPF + + Y +T S ID D AKVTA G GLN F + F ++ G ++ + V + G Y CSY Sbjct: 1222 FNVRDLGYQPKDLEAIVMPPTQKKEVAE--IIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGD------GWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTC--SAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLV----------MGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPF--KIKVDKTQVGDASKVEVSGSGKAKGI-TLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEV------------KSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQ-QYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHGQGIPAGKAFTFTVLTHRAKGHLEAKVVT-PNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRL-RVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNET-SHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNK--FFPGRPAAFQIDT---GLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSY 2046 HSP 9 Score: 122.479 bits (306), Expect = 3.142e-27 Identity = 201/876 (22.95%), Postives = 347/876 (39.61%), Query Frame = 2 Query: 953 YGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVD--CVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG--------------------ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFD---PLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQT-IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEA-GNAANIKV---YGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINN-----LNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLG---VTIEGPM-EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNV 3463 YGPGL+ +G PA FTV + L + + P K +I D NK+ S +++P + GEY++ +K + +SPF+V V S ++ V + ++ + + PG ++ C + G + + +T +E G H + V G + +PF + V KT DA + +G G + +G+ ++ E V T AG+ L V+V GP ++ C K+V L + Y P PG Y + IK+ ++ + SP V G + G V + +VE +G + A KG ++ I+ D G + + P + G + + ++ D ++ SP+ Q F KV A G G++ G T F + + AG V A + G + ++ +D+NDG Y PG++ V V + + +IP+SPFKV + A G +++ +G GI K T+ V+ + G + + + ++ + +V + DG + I + A + +SPF++ + + I+ + TT GQ EF I T G+ + + V+ S+ + E G+ +TP G + +V+ G SP+K+ V KE + YN+ S K+ V +++ T + + P + + VTA G GL K PA+F ID+ L VT +GP E + + +G CS + G V + Y D+ I SPF + Sbjct: 1301 YGPGLQ--NAVVGEPATFTVCAKGSQAKELSVSIEGP--AKSQIKIHD--NKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVG--STSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDG--------------GRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKV-DKTQVGDASKVEVSGSG-KAKGITLQ-ANELLVDTSKAGYGGLSVSVQGPSKAELTC--KEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCT------------GKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTD-DIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPF----QFTVGSFSEGGAHKVRAAGQGVVRG-ETGTFNAFNIYHREAG----VGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHGQGIPAGKAF--TFTVLTHRAKGHLEAKVVTPNNEVDTIDIVPIE--DGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTT--GQKCEFVINTANAGAGI---LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKI----PVEGKE---------------LGGNGYNETS----HVKIDAVAKTSKGTVA---------------VVPEYQGDAA------KVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKG--FVFIKYGDKEIPGSPFAI 2072 HSP 10 Score: 105.531 bits (262), Expect = 4.786e-22 Identity = 90/370 (24.32%), Postives = 162/370 (43.78%), Query Frame = 2 Query: 1424 IEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGF--ADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 I +T + G ++++VF+ G + + + + A++A + + + +FQ + D G+ DL V P + E +I Y P+ G + + I + +P V Y + +GPGL +V +PA F V G + L SI+GP++++I DN DG+ + + P VPGEY VH+ + + SP+ + + + L V ST++ A I + G +++K+ G P +R + G +TP+ G+H + V +P++PFK+ V + G+A+ ++V G G + T +VD AG G + +SV Sbjct: 1159 IVFTATKLGTNTLDVFYGGEHVDHVEYEAIGKLEYERIQAERAKVVVEK-EDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGDGWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVG----------STSEVALPITQQELKGISASIKSPG----GIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSV 1513 HSP 11 Score: 103.219 bits (256), Expect = 2.798e-21 Identity = 125/476 (26.26%), Postives = 198/476 (41.60%), Query Frame = 2 Query: 986 IGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSC----------SYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIE-PVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES-----------KIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILC----DDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGIST-----NKPADFIVNT-KNAGSPSTVKAECFDVTGQTIPVQIRD-NNDGTYSCRYTP 2311 +G PF VDT G + L PK EI D ++Y + IP +++I + A +P +PF V VK D SK+ GPG++ PV ++ T F + +AGPG+V+ + D +G ++V + + F ++YT + G + +NV FAG +I SP + V S G+RV + + + + P +S I +V+ Y G Y D H D P KE+ K KA+GPGL +V + A FE++ +G GAL ++GP++A+ D G+G +V Y PG+Y + I E++ SP+ A + DP ++T ISG+ N+P +F+++T K P VKA Q PV R +N ++ R+ P Sbjct: 525 VGEKIPFRVDTRLCG------VDLVPK-----VEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPT-DASKLKIFGPGVDGPVYSK--EPTRFTIDATQAGPGAVEVALRDDQG--ENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNVDVS---------------GIRVEGLENENLLIGSHLRPTINIGKLEP-KSKGLQLIDEVNGKRYNVPMKINPDGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVIKGTDVNKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKK---DPSQIT------ISGLDQPNYRLNQPINFVIDTSKTKDLP--VKATVPSDFAQLQPVVSRSPSNPRHHNVRFVP 955 HSP 12 Score: 73.559 bits (179), Expect = 2.651e-12 Identity = 111/492 (22.56%), Postives = 215/492 (43.70%), Query Frame = 2 Query: 929 TNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNE---VGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNP----IHLSPFNVDVAPYKE--SKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSE-AKIDCVDNGDGS----ANVTYWP------TVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDN-NDGTYSCRYTPKIPGKHTVI 2338 T++ +++ +GPG++ + P FT+D AG G +++ + + +G+ ++ D N++ +++ Y G Y++ + FA EI SP ++NVK V SG +E + NE +G + + P S ++D G++ +V KI + + + E G H + + F + ++ + V+ +D + A G G+ E V + A F++ + AG L + + GP ++ + Q + C E Y+ + PG Y + IK+G + + SPF V YK+ S+I G +++P F ++T+ +T L PS+ A++ V + S NV + P ++P E L DE + K + QL L D K + + + S F + ++ G+ +++ F G+ +R +G Y + + G++ V+ Sbjct: 604 TDASKLKIFGPGVDGPVYS-KEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLD--NQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVK------PNVDVSGIRVEGLENENLLIGSHLRPTINIGKLEPKSKGLQLIDEVNGKRYNVPMKIN--PDGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVI-----KGTDVNKCKAYGPGL--EQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVE--YVAKAPGDYEMAIKFGKDEQKEHVKGSPFKA-VVDYKKDPSQITISGLDQPNYRLNQPINFVIDTS-KTKDLPVKATVPSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPF--DVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVV 1069 HSP 13 Score: 65.4698 bits (158), Expect = 6.403e-10 Identity = 82/310 (26.45%), Postives = 128/310 (41.29%), Query Frame = 2 Query: 974 EGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNA-AGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSK---------TSNSDAKQAYATGRGI-------QPEGVRVRDV------------AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSY-IPQRPGPYVVDIKYGNNPIHLSPFNVD 1813 +G G FTV T A KG+L+ V+ P + + +I + E +Y+ ++P G + I + + + SPF++ V DP+ ++ASG G+ V G++ F + TA AG G IL + S + E + + YT G + +V + G+ SPF + V K TS+ T +G Q + +V A FQ+ T AG L V V E+ ++ Y CSY IP R +V IKYG+ I SPF ++ Sbjct: 1774 QGIPAGKAFTFTVLTHRA-KGHLEAKVVTPNNEVDTIDIVPIEDGE-SYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGL--VKGTTGQKCEFVINTANAGAG-----ILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVF-IKYGDKEIPGSPFAIE 2073
BLAST of Filamin vs. Ensembl Celegans
Match: fln-1 (FiLamiN (Actin binding protein) homolog [Source:UniProtKB/TrEMBL;Acc:U4PM09]) HSP 1 Score: 745.347 bits (1923), Expect = 0.000e+0 Identity = 489/1511 (32.36%), Postives = 764/1511 (50.56%), Query Frame = 2 Query: 3251 ANTPASFIIDSTEEPPAPLGVTIEGPM--EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKF----NEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEI--EVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVR------------PHRGHLIANKVPSLFTINTRDAGE-SDLELMVTGPN-NESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSE-------AKPEQCYIEGPILNEVPVGKTVTIPVNTQNA----GDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPV---GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKI-DNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX--------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSN----------DSIRET-KSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 + P F ID+T+ P + V + +D +DN DG+ +V Y + PG+Y +NV++ E I SP + + P+ DV+ + GL + S + T+N ++ KG+ +I +R + N DGTYS G+HK+ + +D +PV ++ V V +G+D ++ +AYGPGLE+ + + F +DL+GAG+G L + + GPA A+ + D +G CSV+Y+ + PG Y+++IKF ++H+ GSPF + D S++ GL++ R+ P F +D SK + P+K V + ++P S P +V ++P N I E++Y+ +++ + VL EP+ + + + + H GH VP + RD G +E V GP+ E +N +G + + D+ G Y V + V VPV +E E+ I P T P++ + +L+AK + ++N + + K+G + + + E++ + E+ ER E +Y F+F V G + A+V P+ +K+V +I+N DGTI V+Y P G HEL + NG + G+P KFYVD+ G T YGPGL A FT+ K + A LS+++EGP+K++I+ DNK+GTC +++P PG+Y + +K K + SPF + GE +KRS + VG+TS+V L I++ ++ ++A + SP G EE C ++ L G LG+SFTP+E GEHL+ V R G+ +P +PFKI V + ++G+AS+V++ G G G+ + + +VDT AGYGGLS+S++GPSK E+ C + G V Y PTEPG Y I +K+AD +V SP V G + + + I + + + L L + + + TA ++ P G + E+ L + ++F PK G+HT+SV + HV GSPFQFTVG +GG HKV G GV RG N F IY REAG G++++ IEGPSKA ++F+D+ DG+C V Y+V PG+YV ++KFND+H+P SPF + Y P E R + +A QG G F + H G + A V++P+N+ I I D Y++ FVP E G H +HV ++ +P+ SPFR+ V ++ SG+G+ G TG+ EF ++T+NAG G LTV +DGPSK L+ E E GY Y P APG Y S+KY G H GSPF + + G N D++ +T K V G K V +G GL G+ F +D GLAG ++L VGV PCEEV ++H G+ + +Y + ++ + + +++G+ ++PGSPF I Sbjct: 620 SKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNV-------DVSGIRV--EGLENENLLIGSHLRPTINIGKLEPKSKGL--QLIDEVNGKRYNVPMKINPDGTYSTDTPLMEVGEHKLQLLFDEIPVKEA--VVEVIKGTDVNKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKKDPSQITI--SGLDQPNYRLNQPINFVIDTSKTKDLPVKATV-PSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEK--LVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGH-----VP----FDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEVAAR---VPVMAEKIGRKEDVIKEEIVFHPEIAEHSPTVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYEAIGKLEYERIQAERAKVVVEKEDDVDKYEKQYK---FQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDA-YGDGWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKV---------YIAPATGE------VRKLELAQFHGQGIPAGKAFTFTVLTH-RAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNG-IHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAK-------VTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFAI 2070 HSP 2 Score: 325.865 bits (834), Expect = 4.218e-89 Identity = 293/992 (29.54%), Postives = 449/992 (45.26%), Query Frame = 2 Query: 563 NQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIK------FANSEIPNSPFKVNVKNAAG--DPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDS-VKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHT----EDAGFADLGVNVYGP--GRSLEKCQIKKVSPCLYECSYIP-QRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDP--LKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE-TYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLY----NDEHIKDSPFNVTI 3469 ++DG K +PKQ+LL WI +++P P+ NFT+DWNDG A+GALV++ APG +W W P AL+N ++A+ +A++ L VAPLI P EMI+P++DE ++MTYLSQFP + P + T S + + +P F + G + + + GQ + +KE AY + PT G + + F IP + V A D +K +VG F V A GP V+ +++D G++ V T E+ F EY GLHSVNVF + + SPF + K S GRGI PEG+R DV V + E+ A++ + V P G L + Y P Q P V +K I + VAP SKI+AFG GL GGIV++P F+VE NGE+ L F+++GPS+A+I C + DGSA ++Y PTV G Y V +L D ++I SP++ ++ + P +VT + + P F V+T+ G K E D I R+ G + P P KH + VS V++P +PF V V E +A+ +K++GPG++ + E T F +D AG G + +++ D++ +V + DN DG+FT+KYT + G +F E EI SP ++ ++ + D ++ L NE ++ GS +RP I + ++L + NG V K NP G T+TPL+ ++ + +++ IPV+ A + ++ ++V NK + AYG GL + V A F +D L + + GP +A+ D G+G CSV Y+ K PG Y + + + EH+K SPF + Sbjct: 7 KREDGDNKEETPKQKLLNWIRNRLPGMPISNFTSDWNDGVALGALVNSMAPGALEDWENWSPNDALENTEKAMKSAQDLLKVAPLIAPAEMIHPEIDEMSVMTYLSQFPATKPIIMKPKVQATISNLDKIL---------QVNDPREFDLKLSRDG-FKPKVSIRDEDGQDIHLSLKKVEDKENAYKVKFTPTKIGFIHVDVAANDVHTFETQTIPEASVICQVVPIARLLDYNKTA-----------KVGDDVKFAVVDAIEGP--VEAIVVDPTGKEHRMVILDGTSPGEHSF--EYKIPCIGLHSVNVFHKKLPLTGSPFPLRGKPKNSFK------VWGRGIAPEGIRKNDVVGVHVESLDPEENIANANISLEVLKPSDGSHLPVSVGYNDESQSMDFEYSPKQAPDDLEVLVKVAGEVIE--SHKIHVAPESSSKIRAFGAGLEGGIVNEPCVFDVEMNGESKDLSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVTGIDESKVYNVGEKIP--FRVDTRLCGVDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGVDGPVYSKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGE-EI--SPIEINVKPNVDVSGIRVEGLE--------NENLLI----GSHLRPTINIGKLEPKSKGLQLIDEVNG------------KRYNVPMKINPDGTY----------------STDTPLMEVGEHKL-QLLFDE--IPVKEAVVEVIKGTDV------NKCK----------------------------AYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVV 883 HSP 3 Score: 275.789 bits (704), Expect = 8.383e-74 Identity = 325/1359 (23.91%), Postives = 574/1359 (42.24%), Query Frame = 2 Query: 3809 SRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA---GEA-PLKVNVIDTATKSVKPAQIL-----PKS------TPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNT---QNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHY-TTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFY----NGQPITGSPFKFYVDSTIPSGQVTAYG---PGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSK-AEIQCIDNKNGT----CDVSYLPLAPGDYHIGIKF------MDKHIIG-----SPFTAKIFGEPKKRSQICVGTTSD------VPLRISET-DINNLNAIVISPTGREESCTLKRL-QNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGD--GLNDGMVNETCQF-----------------VVDTRNAGYGGLSLSIEGPSKVEIE-----CHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSL-TER---ILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPF-MLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXX--------XXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 S+IRA+G GLE GI +P F V++ G + L ++EGP+ A+I C + DG+ + Y P G Y V + + KHI SPF + + + ++ GL+ + +RV +D SK GE P +V+ V +IL P S TPGLF+ T IP+ +I+V + VPG+PF V + K+ + G GV + +K P+ FTI+ AG +E+ + E+V+LDV ++ DG+FT +Y PG Y + V++ + + SP + V +EG + +G + +N + G+ V VP I + G + ++G +++QL+F++ IP +++ + + + + + EQ+ + E +V + G + + P+ + R+ + G+G +V+Y G +E+ + + + + GSPFK VD Q+T G P +P T TKD L + PS A++Q + +++ + +V ++P + I I+ +D+ ++ P KI + KK S T++ VP + + ++ + + V P G+E ++ QNG +SF GE+ V +G+ + A+RV + + G + ++ E F + + + + + P V +E + H + + T+ GT ++V Y +V + IG + ER ++ +D + + + N+ GY ++ A V+ P+ E+ EII D +++ PK G H +S+ + + G+P +F V DG + G G++ + + FT+ + + A LS++IEGP+K++I DNKDG+C + PG+Y +K + V SPF +L + E S+ ++GS + + ISA + SP E+ + +D + V F P E G H + V + +P +PF++ +V VSG G G T + NE VDTS AG G L+V++ GPSK +L C+E +SG Y P PG Y I+IK+ ++H+ SP V +G KS + + I ++ + C D + N +D + + P +++ ++ LG +Q+ + + +G H L V + + V GSPF+ V Sbjct: 413 SKIRAFGAGLEGGIVNEPCVFDVEMNGESKD-LSFAVEGPSKAEIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIE---------GLKPSATRVTG-----IDESKVYNVGEKIPFRVDTRLCGVDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGV----DGPVYSKEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNVDVSGIRVEGLENENLLIGSHLRPTINIGKLEPKSKGLQLIDEVNGKRYNVPMKINPD--GTYSTDTPLMEVGEHKLQLLFDE--IP---VKEAVVEVIKGTDVNKCKAYGPGLEQA---VVGEKAVFELDLD-GAGEGALSMEMRGPAKAES--RIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKKDPSQITISGLDQPNYRLNQPINFVIDTSKTKD-----LPVKATVPSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPFDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEV----------------AARVPVMAEKIGRKEDVIKEEIVFHPEIAEHSPTVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYEA-IGKLEYERIQAERAKVVVEKEDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGDGW---ATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSH--------------------------LSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKF-ADHHVKDSPLTVQCTG------------KSAGRVIQTIQKDVEQ------HGICLPDQESHLFLKLLNTSPMD--------ITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTV 1659 HSP 4 Score: 209.534 bits (532), Expect = 1.305e-53 Identity = 223/883 (25.25%), Postives = 379/883 (42.92%), Query Frame = 2 Query: 1964 DCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTG-QTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNG-----------DGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDN--DFKKYKINNLNNTTPIG-QLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFV-AGFTPTVIGPHTVTVECKGNPIGNSPY----------KVIATDRVNTKEY----PETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQ--RSNFEPNEEIIYPVQRTNEKAELR---------------KPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDG-TYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIH-----------------DIV----------------DVSKVKCYGPGLERNGSRVF--TPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTY-IPENIGNCEIEVLYNNMQVPGSPF 4354 + +DN DG+ V Y P V G + + IL + + +P I+ + T YGPGL + + +PA F V K S K + G ++I DN DGT S + P +PG++ V V G + +SPF+V V+ G G +R+ ++ + ++ + + ++++ + G DG + I + +P++PFK+ ++ D K +++ I Q NE + T G + V+ P S+ + +E +G + +TPT G + + ++ + + +SP +VI T + + +++ P+ E+ L + K N + + + + P ++ + +Q + F P E I+ + + A + V A G+G+V+G T +F I E + VTIEGP +A +++ D+ DG C V+Y PG Y+V V +ND+HI DSPF V I P T + + +G G+ P G +F+ FTV + KG ++A + P N+ T + DG +Y+ + P G H I +T DG P+ +SP+ + V DP+ I A G GL +G T Q +F ++ AG G L + ++GP+ A + ++ + G V+Y P PGSY S+K+N H PGSPF +P+ D V D +KV G GL ++ F P+ F +D AG L V V+ TK ++ G + +Y IP+ + + + Y + ++PGSPF Sbjct: 1247 EIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTP----IKFYVDAYGDGWATVYGPGLQNAV-VGEPATFTVCAKG----SQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVM-----------GEGQKRSHLSV----------GSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGL-SVSVQGP--SKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFL--------KLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPAT---GEVRKLELAQFHGQGI-PAG---KAFT-FTV----LTHRAKGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGL----NKFFPGRPAAFQIDTGLAGTNLLMVGVV--TTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGF-VFIKYGDKEIPGSPF 2068 HSP 5 Score: 202.216 bits (513), Expect = 1.987e-51 Identity = 232/850 (27.29%), Postives = 342/850 (40.24%), Query Frame = 2 Query: 3218 TAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----GEAPLKVNVIDTATKSVKPAQILPKSTPG----------LFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCE--PEKVIVTGEG-VRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPF---IVPVHSEA-KPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHS-TVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQ-PSESGL--HELE------------------VFYNGQPITGSPFKFYVD----------------------------STIP-----SGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAV---EGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFT 5524 T YG GL V PA+F + + L V+IEGP +++I DN DGTCS ++P PG Y V+V + +KDSPF V + + + S++ S + A PI + A I +P C V G S++P G+H I + DG V K+P+ + V Q D S++ G G +GIT Q + VD AG GGL +S++GP+ A++ C + K G V Y P +PG Y ++IKF + H+ SP T V+C G ++ RV Q V+ E+ L + +++T+ + + PK + + + P+ G + V+Y + V GSPF V + E KV G+G VR G A F I R+AG + + + GP+ + L+ +H DG YK PG Y V V + ++++P SPF I P E K E G +P GK T V T A G L AK V P + I G S + +VP++ G + + + + +R+ F+ + + P T S G V+N N G G +TVQ PS++ L +ELE V YNG GSPFK V+ + +P + +VTA G GL+ P A F I T AG L + V +GP + E+ +G SY + IK+ DK I GSPF Sbjct: 1297 TVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHL---------------------SVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLT-----------VQCTG----KSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNA------FNIYHREAGVGAVAVTIEGPSKAT--LEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHG---QGIPAGKAFTFTVLTHRA-KGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLD-----GAPMRESPFRLRVG----------GKDLCDP---TAISASGDGLVKGTTGQKCEFVINTA----------NAGAGILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCE-EVVVRHQGSGHYVCSYRIPDRVKGFVFIKYGDKEIPGSPFA 2069 HSP 6 Score: 169.088 bits (427), Expect = 2.504e-41 Identity = 331/1505 (21.99%), Postives = 569/1505 (37.81%), Query Frame = 2 Query: 3350 IDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPF-NQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP----QKFTVD-LEGAGQGGLGLSIEGPADAQ----IQCFDNKDGTCSVQYLP-QKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNV---LNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDL--ELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYI-----EGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENI--------PNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKF----MDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISE-----TDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNA----------SRVKLYGDGLNDGM--------VNETCQFVVDTRNAG-YGGLSLSIEGPSKVEIECH---DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGS-PFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTA--SVISPSGSFEMCEIIALSDNQF----SIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPL----IDGGPHKVHIMGS-GVERGLANDANQFTIYTREAGAGSLSIAIEGPS-KAEI-DFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQ---YSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNC-----QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 +++ + V + P + G V+V ND H F P+ + +A++ Y N T D V+A +G V+AI+ +P + +D G +S Y G H +++ + +P+ SP+ + +G + + +G G+ EGI K ++D E + L + P+D ++++ + +Y P Q P +V +K + I V SK++ +G GLE G V P F V+ + GE+ ++ +K+ Q P + L +Y P G ++ VL + + SPFV V + +P VT G+ + + + K+P F ++TR G DL ++ + P ++ G F D P + + V +VPG+PF V V + I +GP+ ++ P T ++ AG G + G V + + + G TV Y Q+ GAY++ ++F E I PN + + E ++ +H +R ++ + P ++ + R +VP IN DGT + E G H+L++ ++ P+ + + + + + AYGPGL A F + AG G LS+ + GP+KAE + D NG C V Y+ APGDY + IKF +H+ GSPF A + K SQI + R+++ D + + + T + L+ + +S +P H V + SG+ + P +I +I +K+ D D + + D R+ G + + GP E H +G V++ G Y + V P G + E I+ H + AE S V N I ++ A + + + + I L DN I F +LG +T+ V HV ++ +G L I KV + V++ QF + L + P+ K E+ + DN DG+ V Y G + SI N + G+P +D + D + ++ Q +G A F + G +S + P+ K Q+ KI +N+ S +VP G + VHV + + SPFRV+V H G +E + + ++ +I P ++ C G +FT P G++ I++K G + +PF + + TQ G + V+ G G + NE +VD AG L V V GP + E+ K + + +V Y E G + + +++ +H V SP + Sbjct: 175 VEDKENAYKVKFTPTKIGFIHVDVAANDVHT----FETQTIPEASVICQVVPIARLLDY----NKTAKVGDDVKFAVVDAI------EGPVEAIVVDPTGKEHRMVILDGTSPGEHSFEYKIPCIGLHSVNVFHKKLPLTGSPFPL---RGKPKNSFKVWGRGIAPEGIRKNDVVGVHVESLDPEENIANANISLEVLKPSDGSHLPVSVGYNDESQSMDFEYSPKQAPDDLEVLVKVAGEVIESHKIHVAPE---SSSKIRAFGAGLE--GGIVNEPCVFDVEMN--GESKDLSFAVEGPSKAEIGCQERPDGSAIL---SYTPTVAGVYKVGVLADGKHIQDSPFVLRVTEPIEGLKPSATRVT--GIDESKVYNVGEKIP--FRVDTRLCG-VDLVPKVEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPTDASKLKIFGPGVDGPVYSKEPTRFT----IDATQAGPGAVEVALRDDQGENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEISPIEINVKPNVDVSGIRVEGLENENLLIGSH----------LRPTINIGKLE----PKSKGLQLIDEVNGKRYNVPMKINP-DGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVIKGTDV--NKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKA-VVDYKKDPSQITISGLDQPNYRLNQPINFVIDTSKTKDLPVKATVPSDFAQLQPV------VSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPFDVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVVFYINGQEVAARVPVMAEKIGRKEDVIKEEIVFHPEIAEHSP--TVLTYNHPIDAKKKKAHPAIQVLAAKPDAVRLEHIQELVDNGHRVADRIVFTATKLGTNTLDVFYGGEHVDHVEYE-AIGKLEYERIQAERAKVVVEKEDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDA----------------YGDG-WATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPA-KSQI----KIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRS---HLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFT--PREAGEHLITVKRDG-KLVPKAPFKIKVD-------------------------KTQVGDAS--KVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSVQGPSK--AELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTV 1559 HSP 7 Score: 135.191 bits (339), Expect = 4.578e-31 Identity = 130/546 (23.81%), Postives = 238/546 (43.59%), Query Frame = 2 Query: 926 KTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNV-KNAAGDPSKVTASG----PGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIE--YTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDV-AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES---KIKAFGPGLTGGIVSKPAFFEV-ETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDG-TYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 K + RV G G + ++G+ + + + + +P G +EPC + L S+ P GE+ I +K +P +PFK+ V K GD SKV SG GI NE V T++AG G + + + K ++T + LI+ YT E G++++ + FA ++ SP V + K++ + + ++ G+ + D + + + D+ + P + +++ + Y+ + P+ G + + + Y + ++ SPF V + E K++A G G+ G F + GA+ +I+GPS+A ++ D+ DG+ +V Y PGEY V + +D++IP SP+ I T L++ + GI K F V T A ++A+ + + I DG +Y+ R+ PK G H + V+ + ESPF++ V + + I G G+ + T + FV++ AG+G + + + Sbjct: 1372 KDSPFRVLVMGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLG--VSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANE------LLVDTSKAGYGGLSVSV------QGPSKAELTCKEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSA---GRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHG---QGIPAGKAFTFTVLTHRA--KGHLEAKVVTPNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQM 1895 HSP 8 Score: 132.88 bits (333), Expect = 2.702e-30 Identity = 196/870 (22.53%), Postives = 328/870 (37.70%), Query Frame = 2 Query: 1304 FNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVE---TNGETGALGFSIKGPSEAKIDCVDN--GDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLD-TKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAG---------SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI---ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFV-AGFTPTVIGPHTVTVECKGNPIGNSPYKVI---ATDRVNTKEYPE------------TETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNF--------EPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTI---------YPDTKSSSNID------------------DVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSY 3706 FNV P ++ +++ +K+ + I + L++YT K G H +++ G Q+Q +P V + +AT G + V + A F V + + +L V++ GP +S K K C +++P PG Y V +K G + SPF V V G G +S + EV T E + SIK P + C G V++ P GE+ + + D + +PK+P+ +I++D T++ D KV G G GI T + + +V+T AG PS + C +V G YTP PG + + + + + ++ +SP V I+ +E+ + E++ + DI ++D K + D G + +T+ + + +A + SPF+ + S ++ +K+ G+ F + + V S+ ++ ++ N+G + G + V V+ I +SP+KV AT V E + T T L A ++ K P+ V + + P+E K+ N P E + + R K ++A G+GLVKG F+I++ L V ++GP +A +D + G V Y P PGSY +V YN H SPF + + Y +T S ID D AKVTA G GLN F + F ++ G ++ + V + G Y CSY Sbjct: 1220 FNVRDLGYQPKDLEAIVMPPTQKKEVAE--IIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGD------GWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTC--SAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLV----------MGEGQKRSHLSVGSTSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPF--KIKVDKTQVGDASKVEVSGSGKAKGI-TLQANELLVDTSKAGYGGLSVSVQGPSKAELTCKEV------------KSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCTGKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTDDIEMRDLGQ-QYYQLKFTPKMEGIHTLSVMYKDAHVNGSPFQFTVGSFSEGGAHKVRAAGQGVVRGETGTFNAFNIYHREAGVGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHGQGIPAGKAFTFTVLTHRAKGHLEAKVVT-PNNEVDTIDIVPIEDGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRL-RVGGKDLCDPTAISASGDGLVKGTTGQKCEFVINTANAGAGILTVQMDGPSKATLDAYELEKG-YKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNET-SHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNK--FFPGRPAAFQIDT---GLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSY 2044 HSP 9 Score: 122.865 bits (307), Expect = 2.815e-27 Identity = 201/876 (22.95%), Postives = 347/876 (39.61%), Query Frame = 2 Query: 953 YGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVD--CVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG--------------------ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFD---PLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQT-IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEA-GNAANIKV---YGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINN-----LNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLG---VTIEGPM-EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNV 3463 YGPGL+ +G PA FTV + L + + P K +I D NK+ S +++P + GEY++ +K + +SPF+V V S ++ V + ++ + + PG ++ C + G + + +T +E G H + V G + +PF + V KT DA + +G G + +G+ ++ E V T AG+ L V+V GP ++ C K+V L + Y P PG Y + IK+ ++ + SP V G + G V + +VE +G + A KG ++ I+ D G + + P + G + + ++ D ++ SP+ Q F KV A G G++ G T F + + AG V A + G + ++ +D+NDG Y PG++ V V + + +IP+SPFKV + A G +++ +G GI K T+ V+ + G + + + ++ + +V + DG + I + A + +SPF++ + + I+ + TT GQ EF I T G+ + + V+ S+ + E G+ +TP G + +V+ G SP+K+ V KE + YN+ S K+ V +++ T + + P + + VTA G GL K PA+F ID+ L VT +GP E + + +G CS + G V + Y D+ I SPF + Sbjct: 1299 YGPGLQ--NAVVGEPATFTVCAKGSQAKELSVSIEGP--AKSQIKIHD--NKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVG--STSEVALPITQQELKGISASIKSPGGIEEPCFVRLLDG--------------GRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKV-DKTQVGDASKVEVSGSG-KAKGITLQ-ANELLVDTSKAGYGGLSVSVQGPSKAELTC--KEVKSGLIKVLYTPTEPGVYAIAIKFADHHVKDSPLTVQCT------------GKSAGRVIQTIQKDVEQHGICLPDQESHLFLKLLNTSPMDITARLMDPKGHTD-DIEMRDLGQQYYQLKFTPKMEGIHTLSVMYKDAHVNGSPF----QFTVGSFSEGGAHKVRAAGQGVVRG-ETGTFNAFNIYHREAG----VGAVAVTIEGPSKATLEFKDHNDGNCHVDYKVATPGEYVVAVKFNDQHIPDSPFKVYIAPATGEVRKLELAQFHGQGIPAGKAF--TFTVLTHRAKGHLEAKVVTPNNEVDTIDIVPIE--DGESYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGLVKGTT--GQKCEFVINTANAGAGI---LTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKI----PVEGKE---------------LGGNGYNETS----HVKIDAVAKTSKGTVA---------------VVPEYQGDAA------KVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKG--FVFIKYGDKEIPGSPFAI 2070 HSP 10 Score: 105.531 bits (262), Expect = 4.626e-22 Identity = 90/370 (24.32%), Postives = 162/370 (43.78%), Query Frame = 2 Query: 1424 IEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGF--ADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 I +T + G ++++VF+ G + + + + A++A + + + +FQ + D G+ DL V P + E +I Y P+ G + + I + +P V Y + +GPGL +V +PA F V G + L SI+GP++++I DN DG+ + + P VPGEY VH+ + + SP+ + + + L V ST++ A I + G +++K+ G P +R + G +TP+ G+H + V +P++PFK+ V + G+A+ ++V G G + T +VD AG G + +SV Sbjct: 1157 IVFTATKLGTNTLDVFYGGEHVDHVEYEAIGKLEYERIQAERAKVVVEK-EDDVDKYEKQYKFQFNVRDLGYQPKDLEAIVMPPTQKKEVAEIIDNLDGTILVKYTPKVHGSHELSILQNGAQLQGTPIKFYVDAYGDGWATVYGPGLQNAVVGEPATFTVCAKGSQAKELSVSIEGPAKSQIKIHDNKDGTCSAAWVPPVPGEYKVHVKLGGKAVKDSPFRVLVMGEGQKRSHLSVG----------STSEVALPITQQELKGISASIKSPG----GIEEPCFVRLLDGGRLGVSFTPREAGEHLITVKRDGKLVPKAPFKIKVDKTQVGDASKVEVSGSGKAKGITLQANELLVDTSKAGYGGLSVSV 1511 HSP 11 Score: 103.219 bits (256), Expect = 2.465e-21 Identity = 125/476 (26.26%), Postives = 198/476 (41.60%), Query Frame = 2 Query: 986 IGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSC----------SYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIE-PVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES-----------KIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILC----DDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGIST-----NKPADFIVNT-KNAGSPSTVKAECFDVTGQTIPVQIRD-NNDGTYSCRYTP 2311 +G PF VDT G + L PK EI D ++Y + IP +++I + A +P +PF V VK D SK+ GPG++ PV ++ T F + +AGPG+V+ + D +G ++V + + F ++YT + G + +NV FAG +I SP + V S G+RV + + + + P +S I +V+ Y G Y D H D P KE+ K KA+GPGL +V + A FE++ +G GAL ++GP++A+ D G+G +V Y PG+Y + I E++ SP+ A + DP ++T ISG+ N+P +F+++T K P VKA Q PV R +N ++ R+ P Sbjct: 523 VGEKIPFRVDTRLCG------VDLVPK-----VEILDPELNPISYGAREITPGLFEYTLIPDAPIKHKIDVSVAGVSVPGAPFSVKVKEPT-DASKLKIFGPGVDGPVYSK--EPTRFTIDATQAGPGAVEVALRDDQG--ENVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVKPNVDVS---------------GIRVEGLENENLLIGSHLRPTINIGKLEP-KSKGLQLIDEVNGKRYNVPMKINPDGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVIKGTDVNKCKAYGPGLEQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVEYVAKAPGDYEMAIKFGKDEQKEHVKGSPFKAVVDYKK---DPSQIT------ISGLDQPNYRLNQPINFVIDTSKTKDLP--VKATVPSDFAQLQPVVSRSPSNPRHHNVRFVP 953 HSP 12 Score: 73.559 bits (179), Expect = 2.585e-12 Identity = 111/492 (22.56%), Postives = 215/492 (43.70%), Query Frame = 2 Query: 929 TNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNE---VGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNP----IHLSPFNVDVAPYKE--SKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSE-AKIDCVDNGDGS----ANVTYWP------TVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDN-NDGTYSCRYTPKIPGKHTVI 2338 T++ +++ +GPG++ + P FT+D AG G +++ + + +G+ ++ D N++ +++ Y G Y++ + FA EI SP ++NVK V SG +E + NE +G + + P S ++D G++ +V KI + + + E G H + + F + ++ + V+ +D + A G G+ E V + A F++ + AG L + + GP ++ + Q + C E Y+ + PG Y + IK+G + + SPF V YK+ S+I G +++P F ++T+ +T L PS+ A++ V + S NV + P ++P E L DE + K + QL L D K + + + S F + ++ G+ +++ F G+ +R +G Y + + G++ V+ Sbjct: 602 TDASKLKIFGPGVDGPVYS-KEPTRFTIDATQAGPGAVEVALRDDQGENVDLDVLD--NQDGSFTVKYTAQRPGAYQLNVVFAGEEI--SPIEINVK------PNVDVSGIRVEGLENENLLIGSHLRPTINIGKLEPKSKGLQLIDEVNGKRYNVPMKIN--PDGTYSTDTPLMEVGEHKLQLLFDEIPVKEAVVEVI-----KGTDVNKCKAYGPGL--EQAVVGEKAVFELDLDGAGEGALSMEMRGPAKAESRIQDRGNGKCSVE--YVAKAPGDYEMAIKFGKDEQKEHVKGSPFKA-VVDYKKDPSQITISGLDQPNYRLNQPINFVIDTS-KTKDLPVKATVPSDFAQLQPVVSRSPSNPRHHNVRFVPSGKPNVSIPIEIIYDGLKIDEKLVKVLPEVEPQLIKILHDKKKDSLTTTPITTNASHEGHVPF--DVRDCGNVKKIESRVFGPDGKERLNHVRSTEQNGIYDVSFPTDMAGEYCVV 1067 HSP 13 Score: 65.4698 bits (158), Expect = 6.243e-10 Identity = 82/310 (26.45%), Postives = 128/310 (41.29%), Query Frame = 2 Query: 974 EGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNA-AGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSK---------TSNSDAKQAYATGRGI-------QPEGVRVRDV------------AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSY-IPQRPGPYVVDIKYGNNPIHLSPFNVD 1813 +G G FTV T A KG+L+ V+ P + + +I + E +Y+ ++P G + I + + + SPF++ V DP+ ++ASG G+ V G++ F + TA AG G IL + S + E + + YT G + +V + G+ SPF + V K TS+ T +G Q + +V A FQ+ T AG L V V E+ ++ Y CSY IP R +V IKYG+ I SPF ++ Sbjct: 1772 QGIPAGKAFTFTVLTHRA-KGHLEAKVVTPNNEVDTIDIVPIEDGE-SYAMRFVPKETGNHFIHVTLDGAPMRESPFRLRVGGKDLCDPTAISASGDGL--VKGTTGQKCEFVINTANAGAG-----ILTVQMDGPSKATLDAYELEKGYKVRYTPLAPGSYFASVKYNGIHAPGSPFKIPVEGKELGGNGYNETSHVKIDAVAKTSKGTVAVVPEYQGDAAKVTAKGAGLNKFFPGRPAAFQIDTGLAGTNLLMVGVVTTKGPCEEVVVRHQGSGHYVCSYRIPDRVKGFVF-IKYGDKEIPGSPFAIE 2071
BLAST of Filamin vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0303364) HSP 1 Score: 1132.86 bits (2929), Expect = 0.000e+0 Identity = 726/2005 (36.21%), Postives = 1080/2005 (53.87%), Query Frame = 2 Query: 1832 SKIKAFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKGPS----EAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGS--PSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNG-FVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPE---TETPLLIS--------ADYAID-NKAYNKP-SIPVQSAKLT--PVERSNVKTFSNPN-KQRSNFEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVA-NTPASFIIDSTEEPPAPLGVTI---EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFN-GKGIVKAIITNPFNQ-RSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNC-EIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE---------YSVVDF-KFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDV--PLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG-------HTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMIS-GSTQKGPSKPY------NVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 ++++A+GPG+ G +V PA F VET + G++ I+GP+ +A + ++ + + V+Y P G + V + +IPKSP+ ++++ D KV GPG+ +G++ KP F + K+AG P + + + ++ ++R + T+ C Y + G H+V V Y IP SPF V V +A ++ G G++ + + F + + AG G+ + V+ + V+ DG + T Y I + F+ E+ +SPF+V + + ++ IG F + T +G V P S+ ++ + +G + + PT +G + V + C I SP+ IA T +PE P L + +D +KA N P + VQ T PVE N NP+ ++ + P + + V+ R + V A+G L GV N F +D+ E A L V I E +E IDN D T SV +P G+Y + Y + + P + + DV+K+ GL P+ V ++ + F V+ + N G + I +P + V D + Y+P G+H I++ YD +PV SP+ V V G DP+R +AYGPGLE+G+T Q KFTV+ +GAG GGL L+IEGP++A++ C DN+DG+C V YL PG YD++I+F +KHIPGSPF V + + VD SKVK YGPG+E R P+ F VD +AG + V + ++ V ++ K ++ V Y+P G+ +V ++ ++VP SPFV V EP KV V G + +P+ F I+T+ AG++D+ + + P +++ ++ GT+ + D G Y + YG+K + GSPF + + ++C + G + V+ + AGDG ++ K G+ + E+ G + Y G Y++ + F ++IPNGS A + EQYS +TT+ + ++E Y V F K P+ V A V PS + D P + +N DGT++V+Y P E G HEL V YNG+P+ GSPFKF+VDS I SG VTAYGPGL++G A+FTI TK A AGGL++AVEGPSKA+I DNK+GT V YLP APG+Y + ++F DKHI GSP+ AKI GE +KR+QI VG+ S+V P I++ D+ LNA + +P+G EE C LKR+ G +GISFTP+E+GEHLV+V R G+HI NSPFK+ V E E+G+A +VK+ G GL +G + F VDTRNAG+GGLS+SIEGPSK EI+C D DGT ++YKPTEPG YI+N+K+AD +V GSPF V + G S+ E+I R +DA +++IG+ C+L +PG + A V SPS E EI + D +++ F+PKELGVHTVSV+ H+ GSPFQFTVGPL D G H V GSG+ERG+ +A +F ++TREAG GSL+I++EGPSKA+I+F+D KDGSC V+Y+V EPG+Y +KFND H+P SPF + + + D+ + + + F++ +G G + A +++PS + I ID YSV F P ENGIH +HV N IP SPFR+ VG+ +H TG +F ++T NAG G L V+IDGPSKV ++C E E GY Y P PG++ I++KY N HI+GSPF V +G+ + + + +TV ++ G G P V +G GLK A IGK+N+F + A AG ++LYVG+ GP PCEE ++KH G+N + V Y V+++G+++L+++WG +PGSPF+I V Sbjct: 285 NRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPF--PVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPAN-HKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVM-QSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVET--NGETGALGFTVAGP--SQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF--IAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKN-----NPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRV---PLGEKVVVEQTV-----DVSKIKV--DGLEPS-VIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGN-CIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKK----TPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDS-ITSGYVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRNQISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA---------------GDAHKLEVQQFPQGNIQADAPYQFMVRKNG-AKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVGKDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKY-NNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV 2240 HSP 2 Score: 1007.28 bits (2603), Expect = 0.000e+0 Identity = 738/2289 (32.24%), Postives = 1145/2289 (50.02%), Query Frame = 2 Query: 173 AERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAG-SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIE-RAKTNIETYFVVDCKLAGSGDIGISVLDEKMR-DVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKV---RPEIIVKSPNGSRVPVKLQE--TNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV---IATDRVNTKEY-PETETPLLISAD-YAIDNKAYNKPSIPV-----QSAKLT-----------------PVERSNVKTFSNPNKQRSNFEP-NEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVA--NTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYI---DNGDGTCSVNYLPKEPGSYIV-NVLYNDEHIKDSPFNVTIYPDTKSS----SNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFD--NKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFT----------PSQFTVDASKAGEAPLKVNVIDTATKSVKPAQ-----ILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKT--VTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQ----EQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYV---DSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSK----AEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFT-------------AKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNH-DGTCL-VTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQF---------------------TVGPLIDGGPH-------------KVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDG--SCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQI 6655 AER+LAEDAQWK IQ+NTFTRWAN+HLK + I++L+ DL+DGL+LI L++ LS +KRP FR+QKLENV++ L+FL++ EG+++VNIDSSDI DC+LKLILGLIWTLILHYSI+MP+W+GED Q +G G +PKQRLL WI++K+P P+ NFT DW G A+GALVDACAPGLCP+W WDPK A++NA EA+ A++ LNV LI+P E++NP VDE++MMTYLSQ+PN++L APL PKTN RVRAYGPG+E G +G PA FTV+TF+AGKG++D+ + P G+ E ++ + +K L Y+ SYIP EG +++ +KF+ +IP SPF V V+ AGD SKV +GPGI+P G + + TFF++ +AG G + +I+D K SV K+ + + + EY T +GLHSVNVF+AG I +SPF V V+ SDA++ A+GRG+Q GVRV D A+F+++TE AG + V V GPG + KV YEC Y P + G YV+ + + + SPF V V P KES I A+GPGL+ G++ PA F VETNGETGALGF++ GPS+A+I+C DNGDGSA V Y PT GEYAVHILCD+E+IPKSP++AQI L F P V A GPGL +G++ N+P F V+ AG +P V + DV G +PV++++N DGT YTP HTV V+YG V+ P SP +V V +AA ++ +GP ++ + N T+F VD + AG ++ + ++ E+ + +VP DN D T++++ P + G T + + +P KV +E D K K++ L + + +F + GS + + + P G +P K+ + T++ F +TP G HT+ + P+ SP+ V D K Y P E L + + ++ K + + AK+T P E F++ + S F EE + P + V YG G+ G + P F +D E P + V + +D + D G+ +V+Y+P + GS + V +++ + SPF +T++P ++ + +++ K A P ++F ++ K G+ + I NP + ++ GTY S+ P G ++ I Y + SP+ + + + + + + + VD AG G + I A ++I D KDG + Y PG YD+++KF K IP F++ + ++ Y +E + ++V S+ T + + PL + + P+ ++ + G V Y P G+ E+ V YN V GSPF +V +S V G G+ H + + P+ FTI+T+ A L + V GP+ +N ++ DGT + QY PG Y V V +G+K++ GSP+ + E + N++ VG VT+P + + L+A P G PC ++ G+ +S+ P++IG + V + ++I N + + + ++ + T + I + F + +A + C + DGT+ + Y+P+E G + + + + + GSPF V S ++ + T + L+ V PS AEIQ ++ +G V ++P G + + +++ + HI GSPF K G +R VG ++ + E +L V P+ + K ++G +S+ E GE+ V + + RHIP+SPFK++V + G+A ++++ + + QF+V +N G L I PS + +C DG V + P E G + I+VK+ ++P SPF + +G + + H + ++ + + II N T +V S G ++ + + +R+ P G H ++VK +N H+ GSPF+ TV + GG + KV G G+++ NQF+I +AG L + + GP +F G + V Y V + G YV IK+ +EH+PGSPF + + Sbjct: 33 AERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQD-EGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGH--TPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPL---SDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQI-LPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQ--DVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQ-RVPLGE-KVVVEQTVDVSKIKVDGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSK------------VKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKKTPASLP------------AEFEIDTKQA---GQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEY---IEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHV-DSITSGYVTAYGPGLT----HGVTGE-PANFTISTKGASAGGLTMAVEGPSKADINY--HDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---------NQISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQC----------TDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVE--DGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERG--VVGEAAEFNVWTREAGGGSLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA-GDAHKLEVQQFPQGNIQADAPYQFMV-RKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVG----KDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAV-SIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV 2240 HSP 3 Score: 228.024 bits (580), Expect = 4.239e-59 Identity = 304/1254 (24.24%), Postives = 530/1254 (42.26%), Query Frame = 2 Query: 4064 PIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGL-FDVTYIPENIGNCEIEVLYNNMQVPGSPF-VQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNE--SVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVH--SEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVG---NIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIER----TTHHYTTEQSKPIIRTEYSVVDFKFPV-GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQ-----VTAYGPGLSYGRPDMH--AHFTIVTKDAGAGGLSLAVEG--PSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQI-CVGTTSDVPLRISETDINNLNA-----------IVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMV-NETCQFVVDTRNAG----YGGLSLSIEG------PSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDA--NQFTIYTREAGAGSLSIAIEGPSKAEID-FQDNKDGSC--GVTYRVNEPGDYV-CSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX--XXXXXXXXXIHHG----HTGRINEFFVDTSNAGNGALTVTID---GPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAI-SGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGL--AGGDVLYVGVSGPVR-PCEEVNIKHLGNNR---FQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 P+ + ++V+ YGPG+E G V P+ FTV+ AG+ + V+ I ++ A + + L + V+YIP++ G+ ++ V ++ +P SPF V+ ++ + KV VTG G++P+ + K P+ F I +DAG E+++ P N SV V + T+ C+Y + G ++V V Y +P SPF V V S+A+ + G V VG + T+ AG+G + +GP G N++ ++ Y Y P K G Y + + F + + S + P+++ SI + + ++ T F V GP +A + C +NGDG+ V+Y P+ G + + + + + I SPF + +P V A GPGL ++ FT+ AG L + V+ +K ++ +N +GT V+Y P + + + + + SP + G P +++ G +R + N++A I+ T E C + ++ + P G + + G+ +P K+ V + + S++K+ DGL ++ N F+VD G G LS +I PSK+ D + Y P E G + I + Y + VPGSPF VN+ S R + E + + G + ++ PS + C D + ++ + G + ++++ ++H+ GSPF+ V +D P KV + G G+E G ++ F + EAG G +++ + +D + G+C V Y + G + C +KF++ VP SPF++ + S+P K + N+ + + A+L A F I+ I+ + +P K + ++ Y V FVP E G + + + I GSPF++ + + +G + VD AG+GA+T I G V ++ E + ++ Y N PGDY I++K+GG + GS A+ S Y ++ I E T ++ +TQ S+ N K +EI R+ L GG+ V+ VR P +V+ + +NR V Y +E+G H L+V++ V GSPF+ V Sbjct: 277 PLRPKTNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVD-IQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNG---VTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTY---ECHYYPTKEGRYVIMVTFAGQEVAK-SPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGP----SQAEIECH----------DNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF---IAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYV-GVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRVPLGE-KVVV--EQTVDVSKIKV--DGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKI---VQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNV---KSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTC--TDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD--PSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTV-----FPKSEPTKVKVKGVNEKKK-TPASL---------PAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEE-----HTTKVVQQTTQ---SELVNGK--------SEITYRSVAFEKLPLPTTGGN-----VTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHV 1453
BLAST of Filamin vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0089471) HSP 1 Score: 1132.86 bits (2929), Expect = 0.000e+0 Identity = 726/2005 (36.21%), Postives = 1080/2005 (53.87%), Query Frame = 2 Query: 1832 SKIKAFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKGPS----EAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGS--PSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNG-FVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPE---TETPLLIS--------ADYAID-NKAYNKP-SIPVQSAKLT--PVERSNVKTFSNPN-KQRSNFEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVA-NTPASFIIDSTEEPPAPLGVTI---EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFN-GKGIVKAIITNPFNQ-RSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNC-EIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE---------YSVVDF-KFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDV--PLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG-------HTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMIS-GSTQKGPSKPY------NVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 ++++A+GPG+ G +V PA F VET + G++ I+GP+ +A + ++ + + V+Y P G + V + +IPKSP+ ++++ D KV GPG+ +G++ KP F + K+AG P + + + ++ ++R + T+ C Y + G H+V V Y IP SPF V V +A ++ G G++ + + F + + AG G+ + V+ + V+ DG + T Y I + F+ E+ +SPF+V + + ++ IG F + T +G V P S+ ++ + +G + + PT +G + V + C I SP+ IA T +PE P L + +D +KA N P + VQ T PVE N NP+ ++ + P + + V+ R + V A+G L GV N F +D+ E A L V I E +E IDN D T SV +P G+Y + Y + + P + + DV+K+ GL P+ V ++ + F V+ + N G + I +P + V D + Y+P G+H I++ YD +PV SP+ V V G DP+R +AYGPGLE+G+T Q KFTV+ +GAG GGL L+IEGP++A++ C DN+DG+C V YL PG YD++I+F +KHIPGSPF V + + VD SKVK YGPG+E R P+ F VD +AG + V + ++ V ++ K ++ V Y+P G+ +V ++ ++VP SPFV V EP KV V G + +P+ F I+T+ AG++D+ + + P +++ ++ GT+ + D G Y + YG+K + GSPF + + ++C + G + V+ + AGDG ++ K G+ + E+ G + Y G Y++ + F ++IPNGS A + EQYS +TT+ + ++E Y V F K P+ V A V PS + D P + +N DGT++V+Y P E G HEL V YNG+P+ GSPFKF+VDS I SG VTAYGPGL++G A+FTI TK A AGGL++AVEGPSKA+I DNK+GT V YLP APG+Y + ++F DKHI GSP+ AKI GE +KR+QI VG+ S+V P I++ D+ LNA + +P+G EE C LKR+ G +GISFTP+E+GEHLV+V R G+HI NSPFK+ V E E+G+A +VK+ G GL +G + F VDTRNAG+GGLS+SIEGPSK EI+C D DGT ++YKPTEPG YI+N+K+AD +V GSPF V + G S+ E+I R +DA +++IG+ C+L +PG + A V SPS E EI + D +++ F+PKELGVHTVSV+ H+ GSPFQFTVGPL D G H V GSG+ERG+ +A +F ++TREAG GSL+I++EGPSKA+I+F+D KDGSC V+Y+V EPG+Y +KFND H+P SPF + + + D+ + + + F++ +G G + A +++PS + I ID YSV F P ENGIH +HV N IP SPFR+ VG+ +H TG +F ++T NAG G L V+IDGPSKV ++C E E GY Y P PG++ I++KY N HI+GSPF V +G+ + + + +TV ++ G G P V +G GLK A IGK+N+F + A AG ++LYVG+ GP PCEE ++KH G+N + V Y V+++G+++L+++WG +PGSPF+I V Sbjct: 255 NRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPF--PVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPAN-HKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVM-QSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVET--NGETGALGFTVAGP--SQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF--IAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKN-----NPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRV---PLGEKVVVEQTV-----DVSKIKV--DGLEPS-VIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGN-CIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKK----TPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDS-ITSGYVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRNQISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA---------------GDAHKLEVQQFPQGNIQADAPYQFMVRKNG-AKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVGKDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKY-NNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV 2210 HSP 2 Score: 1007.67 bits (2604), Expect = 0.000e+0 Identity = 740/2289 (32.33%), Postives = 1145/2289 (50.02%), Query Frame = 2 Query: 173 AERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAG-SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIE-RAKTNIETYFVVDCKLAGSGDIGISVLDEKMR-DVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKV---RPEIIVKSPNGSRVPVKLQE--TNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV---IATDRVNTKEY-PETETPLLISAD-YAIDNKAYNKPSIPV-----QSAKLT-----------------PVERSNVKTFSNPNKQRSNFEP-NEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVA--NTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYI---DNGDGTCSVNYLPKEPGSYIV-NVLYNDEHIKDSPFNVTIYPDTKSS----SNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFD--NKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFT----------PSQFTVDASKAGEAPLKVNVIDTATKSVKPAQ-----ILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKT--VTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQ----EQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYV---DSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSK----AEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFT-------------AKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNH-DGTCL-VTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQF---------------------TVGPLIDGGPH-------------KVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDG--SCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQI 6655 AER+LAEDAQWK IQ+NTFTRWAN+HLK + I++L+ DL+DGL+LI L++ LS +KRP FR+QKLENV++ L+FL++ EG+++VNIDSSDI DC+LKLILGLIWTLILHYSI+MP+W+GED Q +G G +PKQRLL WI++K+P P+ NFT DW G A+GALVDACAPGLCP+W WDPK A++NA EA+ A++ LNV LI+P E++NP VDE++MMTYLSQ+PN++L APL PKTN RVRAYGPG+E G +G PA FTV+TF+AGKG++D+ + P G+ E ++ + +K L Y+ SYIP EG +++ +KF+ +IP SPF V V+ AGD SKV +GPGI+P G + + TFF++ +AG G + +I+D K SV K+ + + + EY T +GLHSVNVF+AG I +SPF V V+ SDA++ A+GRG+Q GVRV D A+F+++TE AG + V V GPG + KV YEC Y P + G YV+ + + + SPF V V P KES I A+GPGL+ G++ PA F VETNGETGALGF++ GPS+A+I+C DNGDGSA V Y PT GEYAVHILCD+E+IPKSP++AQI L F P V A GPGL +G++ N+P F V+ AG +P V + DV G +PV++++N DGT YTP HTV V+YG V+ P SP +V V +AA ++ +GP ++ + N T+F VD + AG ++ + ++ E+ + +VP DN D T++++ P + G T + + +P KV +E D K K++ L + + +F + GS + + + P G +P K+ + T++ F +TP G HT+ + P+ SP+ V D K Y P E L + + ++ K + + AK+T P E F++ + S F EE + P + V YG G+ G + P F +D E P + V + +D + D G+ +V+Y+P + GS + V +++ + SPF +T++P ++ + +++ K A P ++F ++ K G+ + I NP + ++ GTY S+ P G ++ I Y + SP+ + + + + + + + VD AG G + I A ++I D KDG + Y PG YD+++KF K IP F++ + ++ Y +E + ++V S+ T + + PL + + P+ ++ + G V Y P G+ E+ V YN V GSPF +V +S V G G+ H + + P+ FTI+T+ A L + V GP+ +N DN DGT + QY PG Y V V +G+K++ GSP+ + E + N++ VG VT+P + + L+A P G PC ++ G+ +S+ P++IG + V + ++I N + + + ++ + T + I + F + +A + C + DGT+ + Y+P+E G + + + + + GSPF V S ++ + T + L+ V PS AEIQ ++ +G V ++P G + + +++ + HI GSPF K G +R VG ++ + E +L V P+ + K ++G +S+ E GE+ V + + RHIP+SPFK++V + G+A ++++ + + QF+V +N G L I PS + +C DG V + P E G + I+VK+ ++P SPF + +G + + H + ++ + + II N T +V S G ++ + + +R+ P G H ++VK +N H+ GSPF+ TV + GG + KV G G+++ NQF+I +AG L + + GP +F G + V Y V + G YV IK+ +EH+PGSPF + + Sbjct: 3 AERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQD-EGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGH--TPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPL---SDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQI-LPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQ--DVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQ-RVPLGE-KVVVEQTVDVSKIKVDGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSK------------VKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKKTPASLP------------AEFEIDTKQA---GQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEY---IEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHV-DSITSGYVTAYGPGLT----HGVTGE-PANFTISTKGASAGGLTMAVEGPSKADINYH-DNK-DGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---------NQISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQC----------TDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVE--DGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERG--VVGEAAEFNVWTREAGGGSLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA-GDAHKLEVQQFPQGNIQADAPYQFMV-RKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVG----KDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAV-SIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV 2210 HSP 3 Score: 228.024 bits (580), Expect = 4.555e-59 Identity = 304/1254 (24.24%), Postives = 530/1254 (42.26%), Query Frame = 2 Query: 4064 PIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGL-FDVTYIPENIGNCEIEVLYNNMQVPGSPF-VQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNE--SVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVH--SEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVG---NIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIER----TTHHYTTEQSKPIIRTEYSVVDFKFPV-GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQ-----VTAYGPGLSYGRPDMH--AHFTIVTKDAGAGGLSLAVEG--PSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQI-CVGTTSDVPLRISETDINNLNA-----------IVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMV-NETCQFVVDTRNAG----YGGLSLSIEG------PSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDA--NQFTIYTREAGAGSLSIAIEGPSKAEID-FQDNKDGSC--GVTYRVNEPGDYV-CSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX--XXXXXXXXXIHHG----HTGRINEFFVDTSNAGNGALTVTID---GPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAI-SGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGL--AGGDVLYVGVSGPVR-PCEEVNIKHLGNNR---FQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 P+ + ++V+ YGPG+E G V P+ FTV+ AG+ + V+ I ++ A + + L + V+YIP++ G+ ++ V ++ +P SPF V+ ++ + KV VTG G++P+ + K P+ F I +DAG E+++ P N SV V + T+ C+Y + G ++V V Y +P SPF V V S+A+ + G V VG + T+ AG+G + +GP G N++ ++ Y Y P K G Y + + F + + S + P+++ SI + + ++ T F V GP +A + C +NGDG+ V+Y P+ G + + + + + I SPF + +P V A GPGL ++ FT+ AG L + V+ +K ++ +N +GT V+Y P + + + + + SP + G P +++ G +R + N++A I+ T E C + ++ + P G + + G+ +P K+ V + + S++K+ DGL ++ N F+VD G G LS +I PSK+ D + Y P E G + I + Y + VPGSPF VN+ S R + E + + G + ++ PS + C D + ++ + G + ++++ ++H+ GSPF+ V +D P KV + G G+E G ++ F + EAG G +++ + +D + G+C V Y + G + C +KF++ VP SPF++ + S+P K + N+ + + A+L A F I+ I+ + +P K + ++ Y V FVP E G + + + I GSPF++ + + +G + VD AG+GA+T I G V ++ E + ++ Y N PGDY I++K+GG + GS A+ S Y ++ I E T ++ +TQ S+ N K +EI R+ L GG+ V+ VR P +V+ + +NR V Y +E+G H L+V++ V GSPF+ V Sbjct: 247 PLRPKTNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVD-IQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNG---VTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTY---ECHYYPTKEGRYVIMVTFAGQEVAK-SPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGP----SQAEIECH----------DNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF---IAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYV-GVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRVPLGE-KVVV--EQTVDVSKIKV--DGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKI---VQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNV---KSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTC--TDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD--PSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTV-----FPKSEPTKVKVKGVNEKKK-TPASL---------PAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEE-----HTTKVVQQTTQ---SELVNGK--------SEITYRSVAFEKLPLPTTGGN-----VTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHV 1423
BLAST of Filamin vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0290014) HSP 1 Score: 1130.16 bits (2922), Expect = 0.000e+0 Identity = 623/1498 (41.59%), Postives = 884/1498 (59.01%), Query Frame = 2 Query: 3215 VTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFN-GKGIVKAIITNPFNQ-RSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNC-EIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE---------YSVVDF-KFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDV--PLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG-------HTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMIS-GSTQKGPSKPY------NVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 V A+G GL +G+ PA F+ID+ LGVT+EGP EA I+ DNGDGTC+V YLP E G Y VN+ +N+ HI SPF I P + ++ G G+ P GV ++ + F V+ + N G + I +P + V D + Y+P G+H I++ YD +PV SP+ V V G DP+R +AYGPGLE+G+T Q KFTV+ +GAG GGL L+IEGP++A++ C DN+DG+C V YL PG YD++I+F +KHIPGSPF V + + VD SKVK YGPG+E R P+ F VD +AG + V + ++ V ++ K ++ V Y+P G+ +V ++ ++VP SPFV V EP KV V G + +P+ F I+T+ AG++D+ + + P +++ ++ GT+ + D G Y + YG+K + GSPF + + ++C + G + V+ + AGDG ++ K G+ + E+ G + Y G Y++ + F ++IPNGS A + EQYS +TT+ + ++E Y V F K P+ V A V PS + D P + +N DGT++V+Y P E G HEL V YNG+P+ GSPFKF+VDS I SG VTAYGPGL++G A+FTI TK A AGGL++AVEGPSKA+I DNK+GT V YLP APG+Y + ++F DKHI GSP+ AKI GE +KR+QI VG+ S+V P I++ D+ LNA + +P+G EE C LKR+ G +GISFTP+E+GEHLV+V R G+HI NSPFK+ V E E+G+A +VK+ G GL +G + F VDTRNAG+GGLS+SIEGPSK EI+C D DGT ++YKPTEPG YI+N+K+AD +V GSPF V + G S+ E+I R +DA +++IG+ C+L +PG + A V SPS E EI + D +++ F+PKELGVHTVSV+ H+ GSPFQFTVGPL D G H V GSG+ERG+ +A +F ++TREAG GSL+I++EGPSKA+I+F+D KDGSC V+Y+V EPG+Y +KFND H+P SPF + + + D+ + + + F++ +G G + A +++PS + I ID YSV F P ENGIH +HV N IP SPFR+ VG+ +H TG +F ++T NAG G L V+IDGPSKV ++C E E GY Y P PG++ I++KY N HI+GSPF V +G+ + + + +TV ++ G G P V +G GLK A IGK+N+F + A AG ++LYVG+ GP PCEE ++KH G+N + V Y V+++G+++L+++WG +PGSPF+I V Sbjct: 932 VQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVP-------VPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGN-CIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKK----TPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDS-ITSGYVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRNQISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA---------------GDAHKLEVQQFPQGNIQADAPYQFMVRKNG-AKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVGKDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKY-NNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV 2399 HSP 2 Score: 1107.82 bits (2864), Expect = 0.000e+0 Identity = 816/2493 (32.73%), Postives = 1254/2493 (50.30%), Query Frame = 2 Query: 173 AERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAG-SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIE-RAKTNIETYFVVDCKLAGSGDIGISVLDEKMR-DVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYK---VIATDRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSI------PVQSA-------------KLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEE----PPAPLGVTIEGPMEAKI-DYIDNG--DGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQ--PQKFTVDLEGAGQGGLGLSI---EGPADAQIQCFDNKDGTCSVQYLPQKPGS-YDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTG-PNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPV--------HSEAKPEQC--YIEGPILNEVPVGKT---------VTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIER---TTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNK--NGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKI----FGEPKKRSQICVG-----TTSDVPLRISETDINN-----LNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFV-GENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKV--EIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGA-GSLSIAIEGPSKAEID-FQDNKDGSC-GVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSP------------------------------------------FRXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQE------NESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAI 7249 AER+LAEDAQWK IQ+NTFTRWAN+HLK + I++L+ DL+DGL+LI L++ LS +KRP FR+QKLENV++ L+FL++ EG+++VNIDSSDI DC+LKLILGLIWTLILHYSI+MP+W+GED Q +G G +PKQRLL WI++K+P P+ NFT DW G A+GALVDACAPGLCP+W WDPK A++NA EA+ A++ LNV LI+P E++NP VDE++MMTYLSQ+PN++L APL PKTN RVRAYGPG+E G +G PA FTV+TF+AGKG++D+ + P G+ E ++ + +K L Y+ SYIP EG +++ +KF+ +IP SPF V V+ AGD SKV +GPGI+P G + + TFF++ +AG G + +I+D K SV K+ + + + EY T +GLHSVNVF+AG I +SPF V V+ SDA++ A+GRG+Q GVRV D A+F+++TE AG + V V GPG + KV YEC Y P + G YV+ + + + SPF V V P KES I A+GPGL+ G++ PA F VETNGETGALGF++ GPS+A+I+C DNGDGSA V Y PT GEYAVHILCD+E+IPKSP++AQI L F P V A GPGL +G++ N+P F V+ AG +P V + DV G +PV++++N DGT YTP HTV V+YG V+ P SP +V V +AA ++ +GP ++ + N T+F VD + AG ++ + ++ E+ + +VP DN D T++++ P + G T + + +P KV +E D K K++ L T P+ L +F I+T K + + SP+G+R+ + T GF+ FTPT +G + +++ G PI P++ + +D + + P E ++ A++ ID + + + P ++A P E + N++ P + +I PV L+ V+ G + N F++D ++ L I PM + I G D + Y P E G + + ++Y++ + SPF V + KS D A+ AYGPGL + +KFTV K G G + I P + TCT +N DG+ Y G++ I I + + SP+ V V + DPS+++ YGPG+E G ++ P F VD+ AG G + + + EG ++ D + +V Y+P K GS +KF+E +P SPF + + + +KVK G E+ + P++F +D +AG+A + V + + K+++P L + + G + V+++P+ G + + Y + ++ GSPF + E +K + + + + + S ++ R+AG+ + +T +E V++DV DG F Y + PG+Y + V +G K++P F + HSE E ++ +E+ GK+ +P+ T G ++A+ P G + I++ R G +V Y P++ G++E+ + +N E + + + Y TH T E + I T+ G + V PS + D+ +N DGT++VQY P+ G +++ V + + I GSP+ + + G S M T D L+ +++ PS E C + G +S+ P G++ + +K + KHI SPF + G+ KK G T +D I D N L+ + P+ E CT K +G L IS+ P E G ++VN+ + H+ SPF + V GE +++ D + + C+ L+ + PS V + E + DG V + P E G + ++V+Y++ ++PGSPF +G S + + E +G E N+ + SV PS + E D + + E G + V +K ++RH+ SPF+ V P G HK+ + A+ QF + R+ GA G L I PS + D F DG V + E G + +KFN H+P SPF +++ ++ D + + G KA+F+IN G+++ + PS ++A Y V + P+ G H + V NN I GSP F+ +V G G+ + G+ N+F + ++AGN L V + GP + C+E + YN Y+ G Y + IK+ G HI GSPF + + Sbjct: 3 AERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQD-EGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGH--TPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPL---SDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQI-LPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQ--DVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQ-RVPLGE-KVVVEQTVDVSKIKVDGLEPTAPLNSLQQFRIIT-HGLPKADLAVTITSPSGNRIKAHIIPTAEGFLVNFTPTQLGEYLLSICFGGTPITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVPV------PNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNV----KSGC---DPARCKAYGPGLEKG--LTNQKNKFTVETKGA---GNGGLSLAIEGPSEAKMTCT--DNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVN-EKKKTPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPR--LEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPK-----IQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEK-DGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTG---GNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDSITSGYVTAYGPGLTHGVTGEPANFTISTK----------GASAGGLTMAVEGPS-KADI-NYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRNQISVG---SCSEVTMPGDIT----DDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHAD---NIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDK--DDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSG-SHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKA--DIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA-GDAHKLEVQQFPQGNIQADAPYQFMV--RKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVGKD---------------VADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPS---KVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGP---KGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKW-GEEHIPGSPFQIDV 2399 HSP 3 Score: 661.374 bits (1705), Expect = 0.000e+0 Identity = 578/2035 (28.40%), Postives = 934/2035 (45.90%), Query Frame = 2 Query: 1832 SKIKAFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKGPS----EAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGS--PSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNG-FVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPE---TETPLLIS--------ADYAID-NKAYNKP-SIPVQSAKLT--PVERSNVKTFSNPN-KQRSNFEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVA-NTPASFIIDSTEEPPAPLGVTI---EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAG----EAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVT--IPVNTQNAGDGILSAKNVG----PVGNIVPCSIENERYGHSTVSYVPQKIGA-YEVQLMFNDENIPNGSIRQYAFQPQE--QYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDY-VRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDM-----HAHFTIVTKDAGAGGLSLAVEGPSKAEIQCID--NKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFG--EPKKRSQICVGTTSDVPLRISETDI-----------------------NNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQ----DAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFR--------XXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 ++++A+GPG+ G +V PA F VET + G++ I+GP+ +A + ++ + + V+Y P G + V + +IPKSP+ ++++ D KV GPG+ +G++ KP F + K+AG P + + + ++ ++R + T+ C Y + G H+V V Y IP SPF V V +A ++ G G++ + + F + + AG G+ + V+ + V+ DG + T Y I + F+ E+ +SPF+V + + ++ IG F + T +G V P S+ ++ + +G + + PT +G + V + C I SP+ IA T +PE P L + +D +KA N P + VQ T PVE N NP+ ++ + P + + V+ R + V A+G L GV N F +D+ E A L V I E +E IDN D T SV +P G+Y + Y + + P + + DV+K+ GL PT +S +F + + K + IT+P R + +G + +++P G++ + I + G P+ P+ + GSD ++++A+GPGLE GI QP +F +D GAGQGGLG+++EGP +A I C DN DGTC+V YLP + G Y V+I FNE+HI GSPF I + ++ + G G++ +G + + F VD SK G L + D V P++I+ T +F + Y P G IE++Y+N+ VPGSPFV NV + C+P + G G+ +G + N+ + FT+ T+ AG L L + GP+ + DN DG+ Y PG Y + + + +K++PGSPF V V P + + GP + V ++V V+ AG G ++ K PV N+ +E++ V YVP K G+ Q+ F++ +P F E + ++ T S P +F+ + + P + PRL GT V + P E G ++ + Y + I GSPFK P+G+ A L P + +H + ++AG G ++ + + +EI ID K+G D+ Y PGDY I +KF K I F+ K E S+ T+ V + +++++ N+ A V P+G+ + ++ ++G + + + P+E G H + V +G + SPFK V G V YG GL G+ E F + T+ A GGL++++EGPSK +I HDN DGT V Y PT PG Y ++V++ D ++ GSP+ I G E R+Q +EV+ G++ + +L R AS+ +PSG E C + + I F P+E+G H VSVK +H+ SPF+ TV G KV + G+G++ G + N F++ TR AG G LS++IEGPSKAEI D DG+ ++Y+ EPG Y+ ++KF D HV GSPF +++ + + ++ E D+ I+ IGS+ G+T ++A V SPSN + A I ++++ Y+VHFVP E G+H V V + IPGSPF+ V G G+ G G EF V T AG G+L ++++GPSK + ++ + G + +Y PG+Y + +K+ + HI SPF V +S + ++ E + Q G+ Q PY +F+V A G+ L + P ++ I+ + + V +Y +E G H + V++ +P SPF I V Sbjct: 255 NRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPF--PVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPAN-HKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVM-QSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVET--NGETGALGFTVAGP--SQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF--IAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKN-----NPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRV---PLGEKVVVEQTV-----DVSKIKV--DGLEPTAPL-NSLQQFRIITHGLP---KADLAVTITSPSGNRIKAHIIPTAEG-FLVNFTPTQLGEYLLSICFGGTPITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVPVPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFD-PMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLE--KG--LTNQ-KNKFTVETKGAGNGGLSLAIEGPSEAKMTC-TDNR-DGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNL---RVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKKTPASLP--------AEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKL---EAFPTGE--AKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDSITSG---YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITG-------EGRKRNQISVGSCSEVTMPGDITDDDL-------RALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRE----RDAVPIT---------EIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKF-NDRHIPDSPFKVYVSPDAGDAHK--LEVQQFPQ------GNIQA--DAPY------------------QFMVRKNGAKGE-LDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKV 2175
BLAST of Filamin vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0337100) HSP 1 Score: 1130.16 bits (2922), Expect = 0.000e+0 Identity = 623/1498 (41.59%), Postives = 884/1498 (59.01%), Query Frame = 2 Query: 3215 VTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFN-GKGIVKAIITNPFNQ-RSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNC-EIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE---------YSVVDF-KFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDV--PLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG-------HTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMIS-GSTQKGPSKPY------NVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 V A+G GL +G+ PA F+ID+ LGVT+EGP EA I+ DNGDGTC+V YLP E G Y VN+ +N+ HI SPF I P + ++ G G+ P GV ++ + F V+ + N G + I +P + V D + Y+P G+H I++ YD +PV SP+ V V G DP+R +AYGPGLE+G+T Q KFTV+ +GAG GGL L+IEGP++A++ C DN+DG+C V YL PG YD++I+F +KHIPGSPF V + + VD SKVK YGPG+E R P+ F VD +AG + V + ++ V ++ K ++ V Y+P G+ +V ++ ++VP SPFV V EP KV V G + +P+ F I+T+ AG++D+ + + P +++ ++ GT+ + D G Y + YG+K + GSPF + + ++C + G + V+ + AGDG ++ K G+ + E+ G + Y G Y++ + F ++IPNGS A + EQYS +TT+ + ++E Y V F K P+ V A V PS + D P + +N DGT++V+Y P E G HEL V YNG+P+ GSPFKF+VDS I SG VTAYGPGL++G A+FTI TK A AGGL++AVEGPSKA+I DNK+GT V YLP APG+Y + ++F DKHI GSP+ AKI GE +KR+QI VG+ S+V P I++ D+ LNA + +P+G EE C LKR+ G +GISFTP+E+GEHLV+V R G+HI NSPFK+ V E E+G+A +VK+ G GL +G + F VDTRNAG+GGLS+SIEGPSK EI+C D DGT ++YKPTEPG YI+N+K+AD +V GSPF V + G S+ E+I R +DA +++IG+ C+L +PG + A V SPS E EI + D +++ F+PKELGVHTVSV+ H+ GSPFQFTVGPL D G H V GSG+ERG+ +A +F ++TREAG GSL+I++EGPSKA+I+F+D KDGSC V+Y+V EPG+Y +KFND H+P SPF + + + D+ + + + F++ +G G + A +++PS + I ID YSV F P ENGIH +HV N IP SPFR+ VG+ +H TG +F ++T NAG G L V+IDGPSKV ++C E E GY Y P PG++ I++KY N HI+GSPF V +G+ + + + +TV ++ G G P V +G GLK A IGK+N+F + A AG ++LYVG+ GP PCEE ++KH G+N + V Y V+++G+++L+++WG +PGSPF+I V Sbjct: 932 VQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVP-------VPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGN-CIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKK----TPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDS-ITSGYVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRNQISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA---------------GDAHKLEVQQFPQGNIQADAPYQFMVRKNG-AKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVGKDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKY-NNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV 2399 HSP 2 Score: 1107.82 bits (2864), Expect = 0.000e+0 Identity = 816/2493 (32.73%), Postives = 1254/2493 (50.30%), Query Frame = 2 Query: 173 AERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAG-SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIE-RAKTNIETYFVVDCKLAGSGDIGISVLDEKMR-DVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYK---VIATDRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSI------PVQSA-------------KLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEE----PPAPLGVTIEGPMEAKI-DYIDNG--DGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQ--PQKFTVDLEGAGQGGLGLSI---EGPADAQIQCFDNKDGTCSVQYLPQKPGS-YDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTG-PNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPV--------HSEAKPEQC--YIEGPILNEVPVGKT---------VTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIER---TTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNK--NGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKI----FGEPKKRSQICVG-----TTSDVPLRISETDINN-----LNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFV-GENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKV--EIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGA-GSLSIAIEGPSKAEID-FQDNKDGSC-GVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSP------------------------------------------FRXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQE------NESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAI 7249 AER+LAEDAQWK IQ+NTFTRWAN+HLK + I++L+ DL+DGL+LI L++ LS +KRP FR+QKLENV++ L+FL++ EG+++VNIDSSDI DC+LKLILGLIWTLILHYSI+MP+W+GED Q +G G +PKQRLL WI++K+P P+ NFT DW G A+GALVDACAPGLCP+W WDPK A++NA EA+ A++ LNV LI+P E++NP VDE++MMTYLSQ+PN++L APL PKTN RVRAYGPG+E G +G PA FTV+TF+AGKG++D+ + P G+ E ++ + +K L Y+ SYIP EG +++ +KF+ +IP SPF V V+ AGD SKV +GPGI+P G + + TFF++ +AG G + +I+D K SV K+ + + + EY T +GLHSVNVF+AG I +SPF V V+ SDA++ A+GRG+Q GVRV D A+F+++TE AG + V V GPG + KV YEC Y P + G YV+ + + + SPF V V P KES I A+GPGL+ G++ PA F VETNGETGALGF++ GPS+A+I+C DNGDGSA V Y PT GEYAVHILCD+E+IPKSP++AQI L F P V A GPGL +G++ N+P F V+ AG +P V + DV G +PV++++N DGT YTP HTV V+YG V+ P SP +V V +AA ++ +GP ++ + N T+F VD + AG ++ + ++ E+ + +VP DN D T++++ P + G T + + +P KV +E D K K++ L T P+ L +F I+T K + + SP+G+R+ + T GF+ FTPT +G + +++ G PI P++ + +D + + P E ++ A++ ID + + + P ++A P E + N++ P + +I PV L+ V+ G + N F++D ++ L I PM + I G D + Y P E G + + ++Y++ + SPF V + KS D A+ AYGPGL + +KFTV K G G + I P + TCT +N DG+ Y G++ I I + + SP+ V V + DPS+++ YGPG+E G ++ P F VD+ AG G + + + EG ++ D + +V Y+P K GS +KF+E +P SPF + + + +KVK G E+ + P++F +D +AG+A + V + + K+++P L + + G + V+++P+ G + + Y + ++ GSPF + E +K + + + + + S ++ R+AG+ + +T +E V++DV DG F Y + PG+Y + V +G K++P F + HSE E ++ +E+ GK+ +P+ T G ++A+ P G + I++ R G +V Y P++ G++E+ + +N E + + + Y TH T E + I T+ G + V PS + D+ +N DGT++VQY P+ G +++ V + + I GSP+ + + G S M T D L+ +++ PS E C + G +S+ P G++ + +K + KHI SPF + G+ KK G T +D I D N L+ + P+ E CT K +G L IS+ P E G ++VN+ + H+ SPF + V GE +++ D + + C+ L+ + PS V + E + DG V + P E G + ++V+Y++ ++PGSPF +G S + + E +G E N+ + SV PS + E D + + E G + V +K ++RH+ SPF+ V P G HK+ + A+ QF + R+ GA G L I PS + D F DG V + E G + +KFN H+P SPF +++ ++ D + + G KA+F+IN G+++ + PS ++A Y V + P+ G H + V NN I GSP F+ +V G G+ + G+ N+F + ++AGN L V + GP + C+E + YN Y+ G Y + IK+ G HI GSPF + + Sbjct: 3 AERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQD-EGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGH--TPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPL---SDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQI-LPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQ--DVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQ-RVPLGE-KVVVEQTVDVSKIKVDGLEPTAPLNSLQQFRIIT-HGLPKADLAVTITSPSGNRIKAHIIPTAEGFLVNFTPTQLGEYLLSICFGGTPITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVPV------PNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNV----KSGC---DPARCKAYGPGLEKG--LTNQKNKFTVETKGA---GNGGLSLAIEGPSEAKMTCT--DNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVN-EKKKTPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPR--LEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPK-----IQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEK-DGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTG---GNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDSITSGYVTAYGPGLTHGVTGEPANFTISTK----------GASAGGLTMAVEGPS-KADI-NYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRNQISVG---SCSEVTMPGDIT----DDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHAD---NIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDK--DDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSG-SHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKA--DIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA-GDAHKLEVQQFPQGNIQADAPYQFMV--RKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVGKD---------------VADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPS---KVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGP---KGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKW-GEEHIPGSPFQIDV 2399 HSP 3 Score: 661.374 bits (1705), Expect = 0.000e+0 Identity = 578/2035 (28.40%), Postives = 934/2035 (45.90%), Query Frame = 2 Query: 1832 SKIKAFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKGPS----EAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGS--PSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNG-FVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPE---TETPLLIS--------ADYAID-NKAYNKP-SIPVQSAKLT--PVERSNVKTFSNPN-KQRSNFEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVA-NTPASFIIDSTEEPPAPLGVTI---EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAG----EAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVT--IPVNTQNAGDGILSAKNVG----PVGNIVPCSIENERYGHSTVSYVPQKIGA-YEVQLMFNDENIPNGSIRQYAFQPQE--QYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDY-VRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDM-----HAHFTIVTKDAGAGGLSLAVEGPSKAEIQCID--NKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFG--EPKKRSQICVGTTSDVPLRISETDI-----------------------NNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQ----DAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFR--------XXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 ++++A+GPG+ G +V PA F VET + G++ I+GP+ +A + ++ + + V+Y P G + V + +IPKSP+ ++++ D KV GPG+ +G++ KP F + K+AG P + + + ++ ++R + T+ C Y + G H+V V Y IP SPF V V +A ++ G G++ + + F + + AG G+ + V+ + V+ DG + T Y I + F+ E+ +SPF+V + + ++ IG F + T +G V P S+ ++ + +G + + PT +G + V + C I SP+ IA T +PE P L + +D +KA N P + VQ T PVE N NP+ ++ + P + + V+ R + V A+G L GV N F +D+ E A L V I E +E IDN D T SV +P G+Y + Y + + P + + DV+K+ GL PT +S +F + + K + IT+P R + +G + +++P G++ + I + G P+ P+ + GSD ++++A+GPGLE GI QP +F +D GAGQGGLG+++EGP +A I C DN DGTC+V YLP + G Y V+I FNE+HI GSPF I + ++ + G G++ +G + + F VD SK G L + D V P++I+ T +F + Y P G IE++Y+N+ VPGSPFV NV + C+P + G G+ +G + N+ + FT+ T+ AG L L + GP+ + DN DG+ Y PG Y + + + +K++PGSPF V V P + + GP + V ++V V+ AG G ++ K PV N+ +E++ V YVP K G+ Q+ F++ +P F E + ++ T S P +F+ + + P + PRL GT V + P E G ++ + Y + I GSPFK P+G+ A L P + +H + ++AG G ++ + + +EI ID K+G D+ Y PGDY I +KF K I F+ K E S+ T+ V + +++++ N+ A V P+G+ + ++ ++G + + + P+E G H + V +G + SPFK V G V YG GL G+ E F + T+ A GGL++++EGPSK +I HDN DGT V Y PT PG Y ++V++ D ++ GSP+ I G E R+Q +EV+ G++ + +L R AS+ +PSG E C + + I F P+E+G H VSVK +H+ SPF+ TV G KV + G+G++ G + N F++ TR AG G LS++IEGPSKAEI D DG+ ++Y+ EPG Y+ ++KF D HV GSPF +++ + + ++ E D+ I+ IGS+ G+T ++A V SPSN + A I ++++ Y+VHFVP E G+H V V + IPGSPF+ V G G+ G G EF V T AG G+L ++++GPSK + ++ + G + +Y PG+Y + +K+ + HI SPF V +S + ++ E + Q G+ Q PY +F+V A G+ L + P ++ I+ + + V +Y +E G H + V++ +P SPF I V Sbjct: 255 NRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPF--PVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPAN-HKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVM-QSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVET--NGETGALGFTVAGP--SQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF--IAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKN-----NPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRV---PLGEKVVVEQTV-----DVSKIKV--DGLEPTAPL-NSLQQFRIITHGLP---KADLAVTITSPSGNRIKAHIIPTAEG-FLVNFTPTQLGEYLLSICFGGTPITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVPVPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFD-PMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLE--KG--LTNQ-KNKFTVETKGAGNGGLSLAIEGPSEAKMTC-TDNR-DGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNL---RVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKKTPASLP--------AEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKL---EAFPTGE--AKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDSITSG---YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITG-------EGRKRNQISVGSCSEVTMPGDITDDDL-------RALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRE----RDAVPIT---------EIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKF-NDRHIPDSPFKVYVSPDAGDAHK--LEVQQFPQ------GNIQA--DAPY------------------QFMVRKNGAKGE-LDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKV 2175
BLAST of Filamin vs. Ensembl Fly
Match: cher (gene:FBgn0014141 transcript:FBtr0337101) HSP 1 Score: 1129.78 bits (2921), Expect = 0.000e+0 Identity = 623/1498 (41.59%), Postives = 884/1498 (59.01%), Query Frame = 2 Query: 3215 VTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFN-GKGIVKAIITNPFNQ-RSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNC-EIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE---------YSVVDF-KFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDV--PLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG-------HTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMIS-GSTQKGPSKPY------NVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 V A+G GL +G+ PA F+ID+ LGVT+EGP EA I+ DNGDGTC+V YLP E G Y VN+ +N+ HI SPF I P + ++ G G+ P GV ++ + F V+ + N G + I +P + V D + Y+P G+H I++ YD +PV SP+ V V G DP+R +AYGPGLE+G+T Q KFTV+ +GAG GGL L+IEGP++A++ C DN+DG+C V YL PG YD++I+F +KHIPGSPF V + + VD SKVK YGPG+E R P+ F VD +AG + V + ++ V ++ K ++ V Y+P G+ +V ++ ++VP SPFV V EP KV V G + +P+ F I+T+ AG++D+ + + P +++ ++ GT+ + D G Y + YG+K + GSPF + + ++C + G + V+ + AGDG ++ K G+ + E+ G + Y G Y++ + F ++IPNGS A + EQYS +TT+ + ++E Y V F K P+ V A V PS + D P + +N DGT++V+Y P E G HEL V YNG+P+ GSPFKF+VDS I SG VTAYGPGL++G A+FTI TK A AGGL++AVEGPSKA+I DNK+GT V YLP APG+Y + ++F DKHI GSP+ AKI GE +KR+QI VG+ S+V P I++ D+ LNA + +P+G EE C LKR+ G +GISFTP+E+GEHLV+V R G+HI NSPFK+ V E E+G+A +VK+ G GL +G + F VDTRNAG+GGLS+SIEGPSK EI+C D DGT ++YKPTEPG YI+N+K+AD +V GSPF V + G S+ E+I R +DA +++IG+ C+L +PG + A V SPS E EI + D +++ F+PKELGVHTVSV+ H+ GSPFQFTVGPL D G H V GSG+ERG+ +A +F ++TREAG GSL+I++EGPSKA+I+F+D KDGSC V+Y+V EPG+Y +KFND H+P SPF + + + D+ + + + F++ +G G + A +++PS + I ID YSV F P ENGIH +HV N IP SPFR+ VG+ +H TG +F ++T NAG G L V+IDGPSKV ++C E E GY Y P PG++ I++KY N HI+GSPF V +G+ + + + +TV ++ G G P V +G GLK A IGK+N+F + A AG ++LYVG+ GP PCEE ++KH G+N + V Y V+++G+++L+++WG +PGSPF+I V Sbjct: 962 VQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVP-------VPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGN-CIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKK----TPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDS-ITSGYVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRNQISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA---------------GDAHKLEVQQFPQGNIQADAPYQFMVRKNG-AKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVGKDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKY-NNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV 2429 HSP 2 Score: 1106.66 bits (2861), Expect = 0.000e+0 Identity = 816/2493 (32.73%), Postives = 1254/2493 (50.30%), Query Frame = 2 Query: 173 AERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAG-SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIE-RAKTNIETYFVVDCKLAGSGDIGISVLDEKMR-DVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYK---VIATDRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSI------PVQSA-------------KLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEE----PPAPLGVTIEGPMEAKI-DYIDNG--DGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQ--PQKFTVDLEGAGQGGLGLSI---EGPADAQIQCFDNKDGTCSVQYLPQKPGS-YDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTG-PNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPV--------HSEAKPEQC--YIEGPILNEVPVGKT---------VTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIER---TTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNK--NGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKI----FGEPKKRSQICVG-----TTSDVPLRISETDINN-----LNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFV-GENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKV--EIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGA-GSLSIAIEGPSKAEID-FQDNKDGSC-GVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSP------------------------------------------FRXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQE------NESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAI 7249 AER+LAEDAQWK IQ+NTFTRWAN+HLK + I++L+ DL+DGL+LI L++ LS +KRP FR+QKLENV++ L+FL++ EG+++VNIDSSDI DC+LKLILGLIWTLILHYSI+MP+W+GED Q +G G +PKQRLL WI++K+P P+ NFT DW G A+GALVDACAPGLCP+W WDPK A++NA EA+ A++ LNV LI+P E++NP VDE++MMTYLSQ+PN++L APL PKTN RVRAYGPG+E G +G PA FTV+TF+AGKG++D+ + P G+ E ++ + +K L Y+ SYIP EG +++ +KF+ +IP SPF V V+ AGD SKV +GPGI+P G + + TFF++ +AG G + +I+D K SV K+ + + + EY T +GLHSVNVF+AG I +SPF V V+ SDA++ A+GRG+Q GVRV D A+F+++TE AG + V V GPG + KV YEC Y P + G YV+ + + + SPF V V P KES I A+GPGL+ G++ PA F VETNGETGALGF++ GPS+A+I+C DNGDGSA V Y PT GEYAVHILCD+E+IPKSP++AQI L F P V A GPGL +G++ N+P F V+ AG +P V + DV G +PV++++N DGT YTP HTV V+YG V+ P SP +V V +AA ++ +GP ++ + N T+F VD + AG ++ + ++ E+ + +VP DN D T++++ P + G T + + +P KV +E D K K++ L T P+ L +F I+T K + + SP+G+R+ + T GF+ FTPT +G + +++ G PI P++ + +D + + P E ++ A++ ID + + + P ++A P E + N++ P + +I PV L+ V+ G + N F++D ++ L I PM + I G D + Y P E G + + ++Y++ + SPF V + KS D A+ AYGPGL + +KFTV K G G + I P + TCT +N DG+ Y G++ I I + + SP+ V V + DPS+++ YGPG+E G ++ P F VD+ AG G + + + EG ++ D + +V Y+P K GS +KF+E +P SPF + + + +KVK G E+ + P++F +D +AG+A + V + + K+++P L + + G + V+++P+ G + + Y + ++ GSPF + E +K + + + + + S ++ R+AG+ + +T +E V++DV DG F Y + PG+Y + V +G K++P F + HSE E ++ +E+ GK+ +P+ T G ++A+ P G + I++ R G +V Y P++ G++E+ + +N E + + + Y TH T E + I T+ G + V PS + D+ +N DGT++VQY P+ G +++ V + + I GSP+ + + G S M T D L+ +++ PS E C + G +S+ P G++ + +K + KHI SPF + G+ KK G T +D I D N L+ + P+ E CT K +G L IS+ P E G ++VN+ + H+ SPF + V GE +++ D + + C+ L+ + PS V + E + DG V + P E G + ++V+Y++ ++PGSPF +G S + + E +G E N+ + SV PS + E D + + E G + V +K ++RH+ SPF+ V P G HK+ + A+ QF + R+ GA G L I PS + D F DG V + E G + +KFN H+P SPF +++ ++ D + + G KA+F+IN G+++ + PS ++A Y V + P+ G H + V NN I GSP F+ +V G G+ + G+ N+F + ++AGN L V + GP + C+E + YN Y+ G Y + IK+ G HI GSPF + + Sbjct: 33 AERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQD-EGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGH--TPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPL---SDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQI-LPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQ--DVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQ-RVPLGE-KVVVEQTVDVSKIKVDGLEPTAPLNSLQQFRIIT-HGLPKADLAVTITSPSGNRIKAHIIPTAEGFLVNFTPTQLGEYLLSICFGGTPITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVPV------PNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNV----KSGC---DPARCKAYGPGLEKG--LTNQKNKFTVETKGA---GNGGLSLAIEGPSEAKMTCT--DNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVN-EKKKTPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPR--LEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPK-----IQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEK-DGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTG---GNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDSITSGYVTAYGPGLTHGVTGEPANFTISTK----------GASAGGLTMAVEGPS-KADI-NYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRNQISVG---SCSEVTMPGDIT----DDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHAD---NIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDK--DDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSG-SHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKA--DIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA-GDAHKLEVQQFPQGNIQADAPYQFMV--RKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVGKD---------------VADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPS---KVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGP---KGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKW-GEEHIPGSPFQIDV 2429 HSP 3 Score: 660.218 bits (1702), Expect = 0.000e+0 Identity = 578/2035 (28.40%), Postives = 934/2035 (45.90%), Query Frame = 2 Query: 1832 SKIKAFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKGPS----EAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGS--PSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNG-FVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPE---TETPLLIS--------ADYAID-NKAYNKP-SIPVQSAKLT--PVERSNVKTFSNPN-KQRSNFEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVA-NTPASFIIDSTEEPPAPLGVTI---EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAG----EAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVT--IPVNTQNAGDGILSAKNVG----PVGNIVPCSIENERYGHSTVSYVPQKIGA-YEVQLMFNDENIPNGSIRQYAFQPQE--QYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDY-VRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDM-----HAHFTIVTKDAGAGGLSLAVEGPSKAEIQCID--NKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFG--EPKKRSQICVGTTSDVPLRISETDI-----------------------NNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQ----DAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFR--------XXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 ++++A+GPG+ G +V PA F VET + G++ I+GP+ +A + ++ + + V+Y P G + V + +IPKSP+ ++++ D KV GPG+ +G++ KP F + K+AG P + + + ++ ++R + T+ C Y + G H+V V Y IP SPF V V +A ++ G G++ + + F + + AG G+ + V+ + V+ DG + T Y I + F+ E+ +SPF+V + + ++ IG F + T +G V P S+ ++ + +G + + PT +G + V + C I SP+ IA T +PE P L + +D +KA N P + VQ T PVE N NP+ ++ + P + + V+ R + V A+G L GV N F +D+ E A L V I E +E IDN D T SV +P G+Y + Y + + P + + DV+K+ GL PT +S +F + + K + IT+P R + +G + +++P G++ + I + G P+ P+ + GSD ++++A+GPGLE GI QP +F +D GAGQGGLG+++EGP +A I C DN DGTC+V YLP + G Y V+I FNE+HI GSPF I + ++ + G G++ +G + + F VD SK G L + D V P++I+ T +F + Y P G IE++Y+N+ VPGSPFV NV + C+P + G G+ +G + N+ + FT+ T+ AG L L + GP+ + DN DG+ Y PG Y + + + +K++PGSPF V V P + + GP + V ++V V+ AG G ++ K PV N+ +E++ V YVP K G+ Q+ F++ +P F E + ++ T S P +F+ + + P + PRL GT V + P E G ++ + Y + I GSPFK P+G+ A L P + +H + ++AG G ++ + + +EI ID K+G D+ Y PGDY I +KF K I F+ K E S+ T+ V + +++++ N+ A V P+G+ + ++ ++G + + + P+E G H + V +G + SPFK V G V YG GL G+ E F + T+ A GGL++++EGPSK +I HDN DGT V Y PT PG Y ++V++ D ++ GSP+ I G E R+Q +EV+ G++ + +L R AS+ +PSG E C + + I F P+E+G H VSVK +H+ SPF+ TV G KV + G+G++ G + N F++ TR AG G LS++IEGPSKAEI D DG+ ++Y+ EPG Y+ ++KF D HV GSPF +++ + + ++ E D+ I+ IGS+ G+T ++A V SPSN + A I ++++ Y+VHFVP E G+H V V + IPGSPF+ V G G+ G G EF V T AG G+L ++++GPSK + ++ + G + +Y PG+Y + +K+ + HI SPF V +S + ++ E + Q G+ Q PY +F+V A G+ L + P ++ I+ + + V +Y +E G H + V++ +P SPF I V Sbjct: 285 NRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPF--PVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPAN-HKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVM-QSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVET--NGETGALGFTVAGP--SQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF--IAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKN-----NPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRV---PLGEKVVVEQTV-----DVSKIKV--DGLEPTAPL-NSLQQFRIITHGLP---KADLAVTITSPSGNRIKAHIIPTAEG-FLVNFTPTQLGEYLLSICFGGTPITPRPFRLQCLTGSDSNKVQAFGPGLERGIVGQPAEFMIDTRGAGQGGLGVTVEGPCEAAINCRDNGDGTCNVAYLPTEAGDYTVNITFNERHITGSPFQPLIVPVPNLKNTRVSGIGIQPHGVIMNAATDFMVDMSKVGSNIDSGKLSCAIFD-PMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLE--KG--LTNQ-KNKFTVETKGAGNGGLSLAIEGPSEAKMTC-TDNR-DGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNL---RVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKKTPASLP--------AEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKL---EAFPTGE--AKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDSITSG---YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITG-------EGRKRNQISVGSCSEVTMPGDITDDDL-------RALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRE----RDAVPIT---------EIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKF-NDRHIPDSPFKVYVSPDAGDAHK--LEVQQFPQ------GNIQA--DAPY------------------QFMVRKNGAKGE-LDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKV 2205
BLAST of Filamin vs. Ensembl Zebrafish
Match: flna (filamin A, alpha (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-030131-2145]) HSP 1 Score: 1860.88 bits (4819), Expect = 0.000e+0 Identity = 1079/2571 (41.97%), Postives = 1530/2571 (59.51%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGP-GLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV-APYKESKIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQ-LDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE----TYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNE---FEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETE--TPLLISADYAIDNKAYNKPSIPVQSAKLT-PVERS---NVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKA---------ELRKPN----VTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE---------VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIR-------------------QYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXX---------XXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLT--QTVHMISGSTQKGP----SKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS FR ++RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W D ++ + K +PKQRLLGWI +K+P P+ NF+ DW G A+GALVD+CAPGLCP+W WD + + NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L APL PK N + RAYGP G+E GN + A FTV+T +AG+G + + V +P G +E ++ + +K YS Y+P + G++++ + FA I SPF+V+V A GD SKVTA GPG+EP GN + T+F+V+TA AG G V+ VI+D G+KD+V+ + + + + Y +EG H + + FAG QI SP+ V V + S A GRG+QP+G+RV++ AEF+V+T+ AG DL V + GP E C+ K + +Y Y P PG Y++ I +G I SPF V + + +++A+GPGL G+V K A F VE G+ G LGFS++GPS AKI+C D GDGS +V YWPT PGEYAVH+LC +E+I SP+MA+I K F P KV AYGPGL SG+S KPA+F V+ K G + +K + D G + VQ++DN +GTYSC YTP+ P KHTV+VS+G VNIPESPF++N+ + +KV GPG+ AKT ++ TYF VDC AG GDI I + E D ++ +DN T + + F++ IP +P ++ ++ +D K K + +LN+ F + T G K + + PN +N +TP G + V G+PI SP+ V ++ + + + + D I K+ AK+T P +S V+ +P + F P ++ Y V+ T + A E P V G GL + P F++D T PA L + I + EA++ DNGDGT ++ Y+P PG+Y + + Y D+ + + P + + P ++S V +GPG+ GVF+++ + FTV+A+ + G +K I NP R+ + + DGTY Y+P +G H +++ YD PV KSP+ VPV +G DP+R+R +GPGL+ GIT +P KFTV+ GAG GGLGL++EGP++A++ C DNKDG+C V+Y+P +PG+Y++++ + + I GSPF+VP+HD VD +KVKC G GL N R P F+VDASKAG APL+V V V+PA+++ V+Y+P G I VLY + ++P SP+ VL + + KV +G G+ + +P FTI+ +DAGE L + +T P+ + ++ ++ DGT+ Y D+ G YT+ + YG +P SP+ + +C + I + +G+ I V+ + AG G ++ P G V + G + Y + G Y + + F E+IPN + QYA+ P + +R V+ F G + VR PS + P + +N DGT+TV+Y P+E+GLHE+++ Y+G I GSP +FYVD + SG VTAYGPGL +G + A FT+ TKDAG GGLSLA+EGPSKA+I C DN++GTC VSYLP+ PGDY+I +K+ DK+I GSPF +KI G+ R S + VG+ +D+PL I E D++ L A + +P+GREE C LK L+NG++GISF PKE+GEHLVN+ ++GRHIP+SP + + ++EIG+ASRV++ G GL++ E +F++DTR+AGYGGLSLSIEGPSKV+I D DGTC VTY PTEPG YIIN+K+AD +VPGS F V + G + E I R + AA V+ +G+ C+L+L IP + + TA V SPSG EI+ +N + IRF+P E+GVHTVSVK +HV GSPFQFTVGPL +GG HKV G G+ER A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGS GV+Y V EPGDY SIKFNDEH+P SPF++ P +S S +D+R +++A+LQ+ G + A+F ++ +G G I A V SPS + +++ID ++Y+V F+P ENG++ + V N S IPGSPF++ VGE + G G+ G TG EF V+TS+AG GAL VTIDGPSKV+++CQE GY TY P APG+Y ISIKYGG HI+GSPF I+G+ ++ S+ ET S+ ++ S Q P S V +G GL IG++N F VD AG ++L VGV GP PCEE+ +KHLGN + V+Y ++EKG ++L+V+WG+ +PGSP+ I V Sbjct: 33 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKMFRKYNQRPTFRQMQLENVSVALEFLD-IENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMW---DEEEESEESKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADDWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPAGIEPTGNVVMKKAVFTVETISAGQGEVLVYVEDPAGHREEAKVTANNDKNRTYSVFYVPKVTGQHKVTVLFAGQHISKSPFEVDVGMAQGDSSKVTAQGPGLEPAGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECSVEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTVNVGEACNPS---LCTAKGRGLQPKGLRVKETAEFKVYTKGAGTGDLKVTIKGPKGLEEPCKKKDLGDGVYSFDYYPSTPGNYIITITWGGQHIPRSPFEVKIGSEAGPQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQLSPFMAEIMPAPGKDFYPDKVKAYGPGLQSSGLSVGKPAEFTVDAKLGGK-APLKIQAQDRDGNPVDVQVKDNGNGTYSCSYTPRKPVKHTVMVSWGGVNIPESPFRMNIGAGCHPNKVKVSGPGV--AKTGLKAYDPTYFTVDCAEAGQGDISIGIKCAAGVVGPAEADIDFDIIRNDNDTFTVKYTPPGAGSYTI---MVLFADQTIPMTPIRIKVDPSHDASKVKAEGPGLSRSGVELNKPTHFTVNTKAAG-KAKLDAQFTGPNKGDAVRDFDIIDNHDGTHTVKYTPVQQGNMGLNVTYGGDPIPKSPFAVAIAPSLDLSKVKVAGLGSKMTVGKDQEITVKSKGAGGQGKVGAKVTGPSAKSVPCKVEPGLSPETSQVRFIPRDKGPYEVELTYDGAPIPGSPFPIEAIAPTDPSKVRCSGPGLERAKVGEPGQFVVDCTNAGPAELTIEIISDNGTEAEVHIQDNGDGTYTITYVPLYPGAYTLTIRYGDQDVPNFPARLHVEPAVETSG-------VKVFGPGVEGKGVFREATTDFTVDARALTKTGGNHIKTCINNPSGNRTEALIRDLGDGTYQVEYTPYEEGTHSVEVAYDSSPVPKSPFRVPVTEGCDPARVRVHGPGLQSGITNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCCVEYIPYEPGTYNLNVTYGGQPITGSPFSVPVHDTVDPTKVKCQGQGLGNN-VRANIPQVFSVDASKAGMAPLQVRV-QGPKGVVEPAEVVDNGDQ-THTVSYVPTREGPYSINVLYADEEIPQSPYKVKVLPTHDASKVRCSGPGLNTTG---VPASLPVEFTIDAKDAGEGLLAVQITDPDGKPKKANIRDNQDGTYLVSYVPDMTGRYTILIKYGGDEIPYSPYRIRALPTGDASKCTVTVSIGGHGLGAGVGPTIQIGEQTVITVDAKAAGKGKVTCTVCTPDGGEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVTALEGDSPDQLMQQSQNLQYAYAPNMGQTWATDGQLGMNGLDVAGLRPFDLVIPFTIQKGEITGDVRM----PSGKVAKPDITDNKDGTVTVKYAPTEAGLHEMDIKYDGIHIPGSPLQFYVD-YVNSGHVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPFMSKITGDDSMRMSHLKVGSAADIPLDIGELDLSQLTATLTTPSGREEPCLLKMLRNGHVGISFVPKEIGEHLVNIKKNGRHIPSSPISVMINQSEIGDASRVRVTGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTG--EGRMKESITRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSGKVHKAEIMEGENNTYCIRFVPTEMGVHTVSVKYQGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPFVV-----PVASPS----------DDARRLTVASLQESGLKVNQPASFAVSLNG-AKGVIDAKVHSPSGALEECCVTEIDEDKYAVRFIPRENGLYLIDVKFNGSHIPGSPFKIRVGETGQAGDPGMVSAYGAGLEGGTTGSPCEFIVNTSSAGPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKAKITGSRLVNSHSMHETSSVLVDPVTRSMTTSQQAAPGWASSDASRVVAKGLGLNKGFIGQKNTFSVDCSKAGRNMLLVGVDGPKVPCEEILVKHLGNRLYNVSYQLKEKGEYILVVKWGDEHIPGSPYHITV 2553
BLAST of Filamin vs. Ensembl Zebrafish
Match: CR352234.3 (filamin A, alpha (actin binding protein 280) [Source:NCBI gene;Acc:562529]) HSP 1 Score: 1860.5 bits (4818), Expect = 0.000e+0 Identity = 1081/2563 (42.18%), Postives = 1532/2563 (59.77%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV-APYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQ-LDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE----TYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNE---FEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPET--ETPLLISADYAIDNKAYNKPSIPVQSAKLT-PVERS---NVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKA---------ELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE---------VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYS------IERTTHHYTTEQ------SKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXX---------XXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLT--QTVHMISGSTQKGP----SKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS FR ++RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W D ++ + K +PKQRLLGWI +K+P P+ NF+ DW G A+GALVD+CAPGLCP+W WD + + NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L APL PK N + RAYGPG+E GN + A FTV+T +AG+G + + V +P G +E ++ + +K YS Y+P + G++++ + FA I SPF+V+V A GD SKVTA GPG+EP GN + T+F+V+TA AG G V+ VI+D G+KD+V+ + + + + Y +EG H + + FAG QI SP+ V V + S A GRG+QP+G+RV++ AEF+V+T+ AG DL V + GP E C+ K + +Y Y P PG Y++ I +G I SPF V + + +++A+GPGL G+V K A F VE G + G LGFS++GPS AKI+C D GDGS +V YWPT PGEYAVH+LC +E+I SP+MA+I K F P KV AYGPGL SG+S KPA+F V+ K G + +K + D G + VQ++DN +GTYSC YTP+ P KHTV+VS+G VNIPESPF++N+ + +KV GPG+ AKT ++ TYF VDC AG GDI I + E D ++ +DN T +YTI + F++ IP +P ++ ++ +D K K + +LN+ F + T G K + + PN +N +TP G + V G+PI SP+ V ++ + + + + D I K+ AK+T P +S V+ +P + F P ++ Y V+ T + A E P V G GL + P F++D T PA L + I + EA++ DNGDGT ++ Y+P PG+Y + + Y D+ + + P + + P ++S V +GPG+ GVF+++ + FTV+A+ + G +K I NP R+ + + DGTY Y+P +G H +++ YD PV KSP+ VPV +G DP+R+R +GPGL+ GIT +P KFTV+ GAG GGLGL++EGP++A++ C DNKDG+C V+Y+P +PG+Y++++ + + I GSPF+VP+HD VD +KVKC G GL N R P F+VDASKAG APL+V V V+PA+++ V+Y+P G I VLY + ++P SP+ VL + + KV +G G+ + +P FTI+ +DAGE L + +T P+ + ++ ++ DGT+ Y D+ G YT+ + YG +P SP+ + +C + I + +G+ I V+ + AG G ++ P G V + G + Y + G Y + + F E+IPN + + I + T Q +R V+ F G + VR PS + P + +N DGT+TV+Y P+E+GLHE+++ Y+G I GSP +FYVD + SG VTAYGPGL +G + A FT+ TKDAG GGLSLA+EGPSKA+I C DN++GTC VSYLP+ PGDY+I +K+ DK+I GSPF +KI G+ R S + VG+ +D+PL I E D++ L A + +P+GREE C LK L+NG++GISF PKE+GEHLVN+ ++GRHIP+SP + + ++EIG+ASRV++ G GL++ E +F++DTR+AGYGGLSLSIEGPSKV+I D DGTC VTY PTEPG YIIN+K+AD +VPGS F V + G + E I R + AA V+ +G+ C+L+L IP + + TA V SPSG EI+ +N + IRF+P E+GVHTVSVK +HV GSPFQFTVGPL +GG HKV G G+ER A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGS GV+Y V EPGDY SIKFNDEH+P SPF++ P +S S +D+R +++A+LQ+ G + A+F ++ +G G I A V SPS + +++ID ++Y+V F+P ENG++ + V N S IPGSPF++ VGE + G G+ G TG EF V+TS+AG GAL VTIDGPSKV+++CQE GY TY P APG+Y ISIKYGG HI+GSPF I+G+ ++ S+ ET S+ ++ S Q P S V +G GL IG++N F VD AG ++L VGV GP PCEE+ +KHLGN + V+Y ++EKG ++L+V+WG+ +PGSP+ I V Sbjct: 33 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKMFRKYNQRPTFRQMQLENVSVALEFLD-IENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMW---DEEEESEESKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADDWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNVVMKKAVFTVETISAGQGEVLVYVEDPAGHREEAKVTANNDKNRTYSVFYVPKVTGQHKVTVLFAGQHISKSPFEVDVGMAQGDSSKVTAQGPGLEPAGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECSVEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTVNVGEACNPS---LCTAKGRGLQPKGLRVKETAEFKVYTKGAGTGDLKVTIKGPKGLEEPCKKKDLGDGVYSFDYYPSTPGNYIITITWGGQHIPRSPFEVKIGSEAGPQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQLSPFMAEIMPAPGKDFYPDKVKAYGPGLQSSGLSVGKPAEFTVDAKLGGK-APLKIQAQDRDGNPVDVQVKDNGNGTYSCSYTPRKPVKHTVMVSWGGVNIPESPFRMNIGAGCHPNKVKVSGPGV--AKTGLKAYDPTYFTVDCAEAGQGDISIGIKCAAGVVGPAEADIDFDIIRNDNDTFTV---KYTPPGAGSYTIMVLFADQTIPMTPIRIKVDPSHDASKVKAEGPGLSRSGVELNKPTHFTVNTKAAG-KAKLDAQFTGPNKGDAVRDFDIIDNHDGTHTVKYTPVQQGNMGLNVTYGGDPIPKSPFAVAIAPSLDLSKVKVAGLGSKMTVGKDQEITVKSKGAGGQGKVGAKVTGPSAKSVPCKVEPGLSPETSQVRFIPRDKGPYEVELTYDGAPIPGSPFPIEAIAPTDPSKVRCSGPGLERAKVGEPGQFVVDCTNAGPAELTIEIISDNGTEAEVHIQDNGDGTYTITYVPLYPGAYTLTIRYGDQDVPNFPARLHVEPAVETSG-------VKVFGPGVEGKGVFREATTDFTVDARALTKTGGNHIKTCINNPSGNRTEALIRDLGDGTYQVEYTPYEEGTHSVEVAYDSSPVPKSPFRVPVTEGCDPARVRVHGPGLQSGITNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCCVEYIPYEPGTYNLNVTYGGQPITGSPFSVPVHDTVDPTKVKCQGQGLGNN-VRANIPQVFSVDASKAGMAPLQVRV-QGPKGVVEPAEVVDNGDQ-THTVSYVPTREGPYSINVLYADEEIPQSPYKVKVLPTHDASKVRCSGPGLNTTG---VPASLPVEFTIDAKDAGEGLLAVQITDPDGKPKKANIRDNQDGTYLVSYVPDMTGRYTILIKYGGDEIPYSPYRIRALPTGDASKCTVTVSIGGHGLGAGVGPTIQIGEQTVITVDAKAAGKGKVTCTVCTPDGGEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVTVHTCHAHHLFIHISFISNSGQTLTNGQLGMNGLDVAGLRPFDLVIPFTIQKGEITGDVRM----PSGKVAKPDITDNKDGTVTVKYAPTEAGLHEMDIKYDGIHIPGSPLQFYVD-YVNSGHVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPFMSKITGDDSMRMSHLKVGSAADIPLDIGELDLSQLTATLTTPSGREEPCLLKMLRNGHVGISFVPKEIGEHLVNIKKNGRHIPSSPISVMINQSEIGDASRVRVTGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTG--EGRMKESITRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSGKVHKAEIMEGENNTYCIRFVPTEMGVHTVSVKYQGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPFVV-----PVASPS----------DDARRLTVASLQESGLKVNQPASFAVSLNG-AKGVIDAKVHSPSGALEECCVTEIDEDKYAVRFIPRENGLYLIDVKFNGSHIPGSPFKIRVGETGQAGDPGMVSAYGAGLEGGTTGSPCEFIVNTSSAGPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKAKITGSRLVNSHSMHETSSVLVDPVTRSMTTSQQAAPGWASSDASRVVAKGLGLNKGFIGQKNTFSVDCSKAGRNMLLVGVDGPKVPCEEILVKHLGNRLYNVSYQLKEKGEYILVVKWGDEHIPGSPYHITV 2545
BLAST of Filamin vs. Ensembl Zebrafish
Match: CR352234.2 (filamin A, alpha (actin binding protein 280) [Source:NCBI gene;Acc:562529]) HSP 1 Score: 1860.5 bits (4818), Expect = 0.000e+0 Identity = 1081/2563 (42.18%), Postives = 1532/2563 (59.77%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV-APYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQ-LDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE----TYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNE---FEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPET--ETPLLISADYAIDNKAYNKPSIPVQSAKLT-PVERS---NVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKA---------ELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE---------VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYS------IERTTHHYTTEQ------SKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXX---------XXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLT--QTVHMISGSTQKGP----SKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS FR ++RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W D ++ + K +PKQRLLGWI +K+P P+ NF+ DW G A+GALVD+CAPGLCP+W WD + + NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L APL PK N + RAYGPG+E GN + A FTV+T +AG+G + + V +P G +E ++ + +K YS Y+P + G++++ + FA I SPF+V+V A GD SKVTA GPG+EP GN + T+F+V+TA AG G V+ VI+D G+KD+V+ + + + + Y +EG H + + FAG QI SP+ V V + S A GRG+QP+G+RV++ AEF+V+T+ AG DL V + GP E C+ K + +Y Y P PG Y++ I +G I SPF V + + +++A+GPGL G+V K A F VE G + G LGFS++GPS AKI+C D GDGS +V YWPT PGEYAVH+LC +E+I SP+MA+I K F P KV AYGPGL SG+S KPA+F V+ K G + +K + D G + VQ++DN +GTYSC YTP+ P KHTV+VS+G VNIPESPF++N+ + +KV GPG+ AKT ++ TYF VDC AG GDI I + E D ++ +DN T +YTI + F++ IP +P ++ ++ +D K K + +LN+ F + T G K + + PN +N +TP G + V G+PI SP+ V ++ + + + + D I K+ AK+T P +S V+ +P + F P ++ Y V+ T + A E P V G GL + P F++D T PA L + I + EA++ DNGDGT ++ Y+P PG+Y + + Y D+ + + P + + P ++S V +GPG+ GVF+++ + FTV+A+ + G +K I NP R+ + + DGTY Y+P +G H +++ YD PV KSP+ VPV +G DP+R+R +GPGL+ GIT +P KFTV+ GAG GGLGL++EGP++A++ C DNKDG+C V+Y+P +PG+Y++++ + + I GSPF+VP+HD VD +KVKC G GL N R P F+VDASKAG APL+V V V+PA+++ V+Y+P G I VLY + ++P SP+ VL + + KV +G G+ + +P FTI+ +DAGE L + +T P+ + ++ ++ DGT+ Y D+ G YT+ + YG +P SP+ + +C + I + +G+ I V+ + AG G ++ P G V + G + Y + G Y + + F E+IPN + + I + T Q +R V+ F G + VR PS + P + +N DGT+TV+Y P+E+GLHE+++ Y+G I GSP +FYVD + SG VTAYGPGL +G + A FT+ TKDAG GGLSLA+EGPSKA+I C DN++GTC VSYLP+ PGDY+I +K+ DK+I GSPF +KI G+ R S + VG+ +D+PL I E D++ L A + +P+GREE C LK L+NG++GISF PKE+GEHLVN+ ++GRHIP+SP + + ++EIG+ASRV++ G GL++ E +F++DTR+AGYGGLSLSIEGPSKV+I D DGTC VTY PTEPG YIIN+K+AD +VPGS F V + G + E I R + AA V+ +G+ C+L+L IP + + TA V SPSG EI+ +N + IRF+P E+GVHTVSVK +HV GSPFQFTVGPL +GG HKV G G+ER A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGS GV+Y V EPGDY SIKFNDEH+P SPF++ P +S S +D+R +++A+LQ+ G + A+F ++ +G G I A V SPS + +++ID ++Y+V F+P ENG++ + V N S IPGSPF++ VGE + G G+ G TG EF V+TS+AG GAL VTIDGPSKV+++CQE GY TY P APG+Y ISIKYGG HI+GSPF I+G+ ++ S+ ET S+ ++ S Q P S V +G GL IG++N F VD AG ++L VGV GP PCEE+ +KHLGN + V+Y ++EKG ++L+V+WG+ +PGSP+ I V Sbjct: 33 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKMFRKYNQRPTFRQMQLENVSVALEFLD-IENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMW---DEEEESEESKQKTPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADDWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNVVMKKAVFTVETISAGQGEVLVYVEDPAGHREEAKVTANNDKNRTYSVFYVPKVTGQHKVTVLFAGQHISKSPFEVDVGMAQGDSSKVTAQGPGLEPAGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECSVEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTVNVGEACNPS---LCTAKGRGLQPKGLRVKETAEFKVYTKGAGTGDLKVTIKGPKGLEEPCKKKDLGDGVYSFDYYPSTPGNYIITITWGGQHIPRSPFEVKIGSEAGPQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQLSPFMAEIMPAPGKDFYPDKVKAYGPGLQSSGLSVGKPAEFTVDAKLGGK-APLKIQAQDRDGNPVDVQVKDNGNGTYSCSYTPRKPVKHTVMVSWGGVNIPESPFRMNIGAGCHPNKVKVSGPGV--AKTGLKAYDPTYFTVDCAEAGQGDISIGIKCAAGVVGPAEADIDFDIIRNDNDTFTV---KYTPPGAGSYTIMVLFADQTIPMTPIRIKVDPSHDASKVKAEGPGLSRSGVELNKPTHFTVNTKAAG-KAKLDAQFTGPNKGDAVRDFDIIDNHDGTHTVKYTPVQQGNMGLNVTYGGDPIPKSPFAVAIAPSLDLSKVKVAGLGSKMTVGKDQEITVKSKGAGGQGKVGAKVTGPSAKSVPCKVEPGLSPETSQVRFIPRDKGPYEVELTYDGAPIPGSPFPIEAIAPTDPSKVRCSGPGLERAKVGEPGQFVVDCTNAGPAELTIEIISDNGTEAEVHIQDNGDGTYTITYVPLYPGAYTLTIRYGDQDVPNFPARLHVEPAVETSG-------VKVFGPGVEGKGVFREATTDFTVDARALTKTGGNHIKTCINNPSGNRTEALIRDLGDGTYQVEYTPYEEGTHSVEVAYDSSPVPKSPFRVPVTEGCDPARVRVHGPGLQSGITNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCCVEYIPYEPGTYNLNVTYGGQPITGSPFSVPVHDTVDPTKVKCQGQGLGNN-VRANIPQVFSVDASKAGMAPLQVRV-QGPKGVVEPAEVVDNGDQ-THTVSYVPTREGPYSINVLYADEEIPQSPYKVKVLPTHDASKVRCSGPGLNTTG---VPASLPVEFTIDAKDAGEGLLAVQITDPDGKPKKANIRDNQDGTYLVSYVPDMTGRYTILIKYGGDEIPYSPYRIRALPTGDASKCTVTVSIGGHGLGAGVGPTIQIGEQTVITVDAKAAGKGKVTCTVCTPDGGEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVTVHTCHAHHLFIHISFISNSGQTLTNGQLGMNGLDVAGLRPFDLVIPFTIQKGEITGDVRM----PSGKVAKPDITDNKDGTVTVKYAPTEAGLHEMDIKYDGIHIPGSPLQFYVD-YVNSGHVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCTDNQDGTCTVSYLPVLPGDYNIIVKYNDKNIPGSPFMSKITGDDSMRMSHLKVGSAADIPLDIGELDLSQLTATLTTPSGREEPCLLKMLRNGHVGISFVPKEIGEHLVNIKKNGRHIPSSPISVMINQSEIGDASRVRVTGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTG--EGRMKESITRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSGKVHKAEIMEGENNTYCIRFVPTEMGVHTVSVKYQGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDEHIPDSPFVV-----PVASPS----------DDARRLTVASLQESGLKVNQPASFAVSLNG-AKGVIDAKVHSPSGALEECCVTEIDEDKYAVRFIPRENGLYLIDVKFNGSHIPGSPFKIRVGETGQAGDPGMVSAYGAGLEGGTTGSPCEFIVNTSSAGPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKAKITGSRLVNSHSMHETSSVLVDPVTRSMTTSQQAAPGWASSDASRVVAKGLGLNKGFIGQKNTFSVDCSKAGRNMLLVGVDGPKVPCEEILVKHLGNRLYNVSYQLKEKGEYILVVKWGDEHIPGSPYHITV 2545
BLAST of Filamin vs. Ensembl Zebrafish
Match: flnca (filamin C, gamma a (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-070503-1]) HSP 1 Score: 1064.29 bits (2751), Expect = 0.000e+0 Identity = 767/2146 (35.74%), Postives = 1097/2146 (51.12%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKT-NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES---KIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNTTPIGQL-NEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV----------IATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIY---------PVQRTNEKAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQ-PQKFTVDLEGAG--QGG--LGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTP-GLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIV---PVHSEAKPEQCYIEGPILNEVPVGKT--VTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTH---HYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFK-FYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCI--DNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSP--FTAKIFGEPKKRSQ---ICVGTTSDVPLRISETDIN----NLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSS-SLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTV 6370 E++LAEDA WK IQ+NTFTRW N+HLK N + DLQ DL DGLKLI+L++ LS +R H RPNFR KLENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W+ ED D + K +PKQRLLGWI +K+P P+ NF DW DG A+GALVD CAPGLCP+W WDP Q ++NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L AP+ PK + +AYGPG+E +GN + PA FTV+T AG G + + V +P+G E ++ + +K+ +S +Y+P +EG +++ + FA +I SPF VNV A GDP+KV A GPG+EP GN + T+F+++TA AG G V VI+D + + ++V+ + + +N F Y EG H+++V FAG I SSPF V +S S+A ATGRG+QP+GVRV++VA+F V T+ AG +L V+V GPG ++ V +++C Y P +PG Y V+I +G PI SPF V+V+ KE+ K++A+GPGL G+V K A F VE G E G LGFSI+GPS+AKI+C D GDGS +V YWPT PG+YAVH++CDDE+I SP+MA I P KV A+GPGL +G++ NK F V+ + AG +K D G I +QI D DGT+ C Y P P KHT+I+++G VNIP+SPF+V V E + +KVYGPG+E+ K N TYF VDC AG GD+ I + E D ++ +DN T YTI + F++ EIP SPFKV ++ +D K + +N T ++ F I T G K +PE+ K+ + +N + +T G + V G+PI SP+K+ + +N K + +++ A N SI S + P + + KT + P EE Y PV + E P V AYG GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV YLP E G Y +N+LY + HI SPF + P D KVTA GPGL + FTV+ + I+++ Q C + NN DGT+S +Y+P G H I I Y G V KSP V V D S I+ YGPG+E +G+ ++ F VD +GG + + I P+ A + D DGT V+Y + G + + + ++E +P SPF V + + D ++V+ YGPGLE G V P+ FTV+ AG A L + + + A++L K G V Y+P G+ +I + Y +PGSPF V + + KV +G G+ + + VP FT++ AG + LE+ + GP + V N+ DGT T Y G +TV V Y N+ VP SP+ V P H +K GP L+ V + V ++ ++AG G+L+ + + P G SI + R G TVSYVP G Y + + + +NIP AF + T H E P I+ V V V P+ + + N DGT + Y E G + + + + GQ I SPF+ D + T +P ++ G LS V PS + DNK+GT V + P G + + IK+ HI GSP F + + +C GT + P + N L+ V P+ E SC K ++G +S+ P G++ + V HIP SPF + ++ L LN G + + +T + Y L+ SI+ PS E C + H G +++ P E G + ++V+ + +V SPF + +G PS R+ + V E + S+ PS C+ + D + + P E G + +++K ++H+ GSPF V Sbjct: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKGVTDLQKDLGDGLKLISLLEVLSQKKMYRKHHVRPNFRQMKLENVSVALEFLDR-ERIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDED----DEEVKKLTPKQRLLGWIQNKVPELPINNFNKDWRDGKALGALVDNCAPGLCPDWQTWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPVKPKQLYPKKAKAYGPGIEPQGNMVLKPAVFTVETLEAGLGEVIVYVEDPEGHTEEAKVVANNDKKRTFSVTYVPKVEGRHKVKVLFAGQDIDKSPFMVNVAKALGDPNKVQARGPGLEPEGNVAHKPTYFDIYTAGAGAGDVSVVIVDPQNKNNTVEVILENKGDNIFRCTYKPVLEGPHTIHVTFAGQPIPSSPFKVNISEA---SNANACRATGRGLQPKGVRVKEVADFTVFTKGAGTGELKVSVKGPGGVEVPVKVCDVGDGVFKCDYCPVKPGKYTVNITWGGQPIPRSPFEVEVS--KEAGTQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVKAFGPGLEPTGVTVNKSTQFTVDAREAGK-GGLKIYAQDAEGCVIDIQITDKGDGTFVCVYVPTKPVKHTIIITWGEVNIPKSPFRVLVGEGCHPDKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTV---KYTPPGPGRYTIMVVFADQEIPSSPFKVKVDPSHDAGKVRAEGPGINKTGVQVEIPTHFTIFTKGAG-KAKPEVHFKTAAKGNAVKDFEIIDNHDYSYTVKYTALHQGEMAIVVTHGGDPIPKSPFKITVAPSLDLGKVKVQGLNEKVEVGKDQEFIVNTKGAGGQGKVNV-SITSPSGRPIPCKLESDKT---KEATCVKYIPPEEGHYKVDITYDGNPVPESPFSVEGLMPADPSKVRAYGPGLKGGIVGQPAKFSIDTKGAGAGGLGLTLEGPCEAKIECQDNGDGTCSVVYLPTEAGDYNINILYGEAHIPGSPFKAVVKPAL-------DAGKVTASGPGLERAKA--GEVASFTVDCS--RAGEAELTIEIVSDSGAQAEVC-IQNNKDGTFSVTYTPLFHGVHTITIKYGGQQVPKSPIHVKVEPSVDTSGIKVYGPGVEPKGVLREVTTHFIVDARAHAKTKGGNHVKIRIINPSGANTDAYITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFKVSVVEGCDPTRVRAYGPGLE--GGIVNKPNCFTVETRGAGTAGLGLTI-----EGASEAKMLCKDNKDGSCSVEYMPFTAGDYDINIAYGGQPIPGSPFRVQVKDVVDVSKVKCSGPGL----ANKVTAHVPQTFTVDCSKAGVAPLEVQLYGPKGTLEPVVVKNNRDGTHTVNYTPAQEGPHTVSVKYANQEVPSSPYKVNSAPSHDASK---VRASGPGLDTTGVAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKASIHDNRDGTYTVSYVPDMTGRYTITIKYGGDNIPYSPYNVQAFPTGDASKCLLTVSIGGHGVAESLGPNIQMSEETVITVDAKAAGKGKVTCTVQTPNGMELDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVMATDQPVAPRDDT---------KPMFQPLNLVIPFTVQQGELSGEVRMPSGKTARPFIRDNKDGTVTVQFQPTEKGLHEMDIKYDGNHIPGSPLQFYVDVTNSGMVTAYGPGLCHGTVNK-PASFTVVTKNAGQGGLSLAVEGPSKAEISC--KDNKDGTCTVSYLPTTPGDYNIIVKFDNSHIPGSPFTAKITGDD-------SLRRSQLNVGTAADVSLKITET-DLSY--LTASIKAPSGKEEPCLLKRLPNRHIG---LSFTPKEVGEHEVSVRKSGKHVNNSPFKIMVG--PSEIGEASRVKAFGKGLVEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDINCDDV--EDGTCKVTYCPTEPGNYIINIKFADKHIPGSPFTVKV 2103 HSP 2 Score: 1004.2 bits (2595), Expect = 0.000e+0 Identity = 761/2301 (33.07%), Postives = 1125/2301 (48.89%), Query Frame = 2 Query: 941 RVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE----SKIKAFGPGL--TGGIVSKPAFFEVETNGETGALGFSIKGPSEA----KIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPS-TVKAECF-DVTGQT---IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE--TYFVVDCKLAGSGD----IGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQ--ETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV---IATDRVNTKEYPETETPLLIS--ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN-FEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKP-IDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE---------VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPK-KRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPG------YNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSK--AEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIH----HGHTGRINE--FFVDTSNAGNGALTVTIDGPSKVQLNC--QENESGYN-FTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 +V+A GPGLE EGN P F + T AG G++ +++++P+ + E+ + + C+Y P +EG + I + FA IP+SPFKVN+ A+ + + A+G G++P G V F VFT AG G + + G + V K+ + F +Y + G ++VN+ + G I SPF V VS + + ++ A G G++ V A+F V LG ++ GP ++ +C K C + Y P PG Y V + + I SPF + P K+KAFGPGL TG V+K F V+ E G G I I D GDG+ Y PT P ++ + I + NIPKSP+ L + P KV YGPG+ +G+ N+P F V+ AG ++ +C V G I I N++ T++ +YTP PG++T++V + + IP SPFKV V + +A ++ GPGI + +E T+F + K AG + ++D ++ DN D ++T+KYT G + + IP+SPFK+ + D K K+ LN +G+ EF + T G + + + + SP+G +P KL+ +T + P G + V + GNP+ SP+ V + D + Y ++ A ++ID K L + ++ N + S + P E Y + + K L VTA G GL + A ASF +D + A L + I + +A++ +N DGT SV Y P G + + + Y + + SP +V + P D + + YGPG+ P GV ++ + F V+A+ G VK I NP + + + DGTY Y+ DG H I++ YD V V KSP+ V V +G DP+R+RAYGPGLE GI +P FTV+ GAG GLGL+IEG ++A++ C DNKDG+CSV+Y+P G YD++I + + IPGSPF V + D+VDVSKVKC GPGL N P FTVD SKAG APL+V + K ++ + G V Y P G + V Y N +VP SP+ N S + KV +G G+ +A +P FTI+ RDAG+ L + + P + + ++ DGT+T Y D+ G YT+ + YG N+P SP+ V +C + I + + + I V+ + AG G ++ P G + + G + Y + G Y + + F ++IP + A +Q R + +KP+ + V+ F G + VR PS + P + +N DGT+TVQ+QP+E GLHE+++ Y+G I GSP +FYVD T SG VTAYGPGL +G + A FT+VTK+AG GGLSLAVEGPSKAEI C DNK+GTC VSYLP PGDY+I +KF + HI GSPFTAKI G+ +RSQ+ VGT +DV L+I+ETD++ L A + +P+G+EE C LKRL N ++G+SFTPKEVGEH V+V +SG+H+ NSPFKI VG +EIG ASRVK +G GL + E +F VDTRNAGYGGL LSIEGPSKV+I C D DGTC VTY PTEPG YIIN+K+AD ++PGSPF V + G + + I R + AA ++ +G+ C+LNL IPG Q T + S ++ E +S + VH V + G PF+ + G ++ G+ + G E G ++ + P A+ + D+ + + V + E G + ++K+ EHVPGSPF + + K + + A F I G +S V PS E + + V +V E G + V + NN IP SPF V V ++ + ++N+ F N G + + PS V C E +S N ++P G ++I +K+ G +HI GSPF V + E +S+ P V G GL+ G +EF+V+ AG L V + GP + + N G ++++Y G +L+ +++G + GSPF+ V Sbjct: 384 KVQARGPGLEPEGNVAHKPTYFDIYTAGAGAGDVSVVIVDPQNKNNTVEVILENKGDNIFRCTYKPVLEGPHTIHVTFAGQPIPSSPFKVNISEAS-NANACRATGRGLQPKGVRVKEVADFTVFTKGAGTGELKVSVKGPGGVE--VPVKVCDVGDGVFKCDYCPVKPGKYTVNITWGGQPIPRSPFEVEVSKE---AGTQKVRAWGPGLKTG--MVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSC--DVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVKAFGPGLEPTGVTVNKSTQFTVDAR-EAGKGGLKIYAQDAEGCVIDIQITDKGDGTFVCVYVPTKPVKHTIIITWGEVNIPKSPFRV---LVGEGCHPDKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGPGRYTIMVVFADQEIPSSPFKVKVDPSHDAGKVRAEGPGINKTGVQVEIPTHFTIFTKGAGKAKPEVHFKTAAKGNAVKDFEII--DNHDYSYTVKYTALHQGEMAIV-VTHGGDPIPKSPFKITVAPSLDLGKVKVQGLNEKVEVGKDQEFIVNTKGAGGQGKVNVSITSPSGRPIPCKLESDKTKEATCVKYIPPEEGHYKVDITYDGNPVPESPFSVEGLMPADPSKVRAYGPGLKGGIVGQPAKFSIDTKGAGAGG---LGLTLEGPCEAKIECQDNGDGTCSVVYLPTEAGDYNINILYGEAHIPGSPFKAVVKPALDAGKVTASGPGLERAKAGEVASFTVDCSRAGEAELTIEIVSDSGAQAEVCIQNNKDGTFSVTYTPLFHGVHTITIKYGGQQVPKSPIHVKVEPSV-------DTSGIKVYGPGVEPKGVLREVTTHFIVDARAHAKTKGGNHVKIRIINPSGANTDAYITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFKVSVVEGCDPTRVRAYGPGLEGGIVNKPNCFTVETRGAGTAGLGLTIEGASEAKMLCKDNKDGSCSVEYMPFTAGDYDINIAYGGQPIPGSPFRVQVKDVVDVSKVKCSGPGLA-NKVTAHVPQTFTVDCSKAGVAPLEVQLY--GPKGTLEPVVVKNNRDGTHTVNYTPAQEGPHTVSVKYANQEVPSSPYKVNSAPSHDASKVRASGPGLDTTG---VAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKASIHDNRDGTYTVSYVPDMTGRYTITIKYGGDNIPYSPYNVQAFPTGDASKCLLTVSIGGHGVAESLGPNIQMSEETVITVDAKAAGKGKVTCTVQTPNGMELDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVMA---TDQPVAPR-------DDTKPMFQPLNLVIPFTVQQGELSGEVRM----PSGKTARPFIRDNKDGTVTVQFQPTEKGLHEMDIKYDGNHIPGSPLQFYVDVT-NSGMVTAYGPGLCHGTVNKPASFTVVTKNAGQGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTTPGDYNIIVKFDNSHIPGSPFTAKITGDDSLRRSQLNVGTAADVSLKITETDLSYLTASIKAPSGKEEPCLLKRLPNRHIGLSFTPKEVGEHEVSVRKSGKHVNNSPFKIMVGPSEIGEASRVKAFGKGLVEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDINCDDVEDGTCKVTYCPTEPGNYIINIKFADKHIPGSPFTVKVTG--EGRMKQSITRKRQAASIASVGSTCDLNLKIPGNWFQMLSAQERLTRTFTRSSHTYTRTERTEISKTHGG----ETKREVH-VEESTQVGGGGGDPFRDVFESFL--GRDRLGSFGTIRQEG-------------ETGIQGMTAQVTSPGGNLADAEIVDSGNSTYRVRFVPTEMGSHTVNVKYRGEHVPGSPFQFTVGPLGEGGFHK--------------VRAGGTGLERAVAKVPAEFSIWTREAGAGGLSIAVEGPSKAE--INFEDRKDGSCGVSYVVQEPGDYEVSIKFNNEHIPDSPFIVPVATLSDDARRLTVTSLQEKDLKVNQEASFAVQRNGARGVIDAKVHAPSGVVEECYVTELDSDKNAIRFIPRENGVHSIDVKFNG-SHIPGSPFKVRVG-----------EAESV---------------GDPGMVSAFGPGLEGGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEG---YKISYTPMAPGNYLICIKYGGPQHIVGSPFKAKV 2568 HSP 3 Score: 642.499 bits (1656), Expect = 0.000e+0 Identity = 478/1529 (31.26%), Postives = 741/1529 (48.46%), Query Frame = 2 Query: 3215 VTAYGEGLV-KGVANTPAS-FIIDSTEEPPAPLG----VTIEGPMEAKID-YI-DNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQ-PQKFTVDLEGAGQGGLGLSIEGPADAQ--IQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVT----GEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIR------TEYSVVDFKFPVGPVFDYV----RAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPF--KFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNK--NGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKI----FGEPKKRSQICVGTTSDVPLRISETDINNLNA-------IVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFV-GENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXX---------XIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-----LTQTVHMISGSTQKGPSKPYN----VKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 + YG G+ KGV + FI+D+ G + I P A D YI D GDGT V Y E G +++ V Y++ + SPF V++ D +V AYGPGL G + + FTV + G G+ I + C +N DG+ S Y P G + I+I Y G P+ SP+ V V D S+++ GPGL +T PQ FTVD AG L + + GP + +N+DGT +V Y P + G + VS+K+ + +P SP+ V D SKV+ GPGL+ G P +FT+DA AG+ L V ++D K K + + + G + V+Y+P+ G I + Y +P SP+ + + K ++T G GV G I ++ T++ + AG+ + V PN +++DV + DGTF Y PG Y + + +G +++P SPF V + + + P+ + + IP Q G LS + P G I + + G TV + P + G +E+ + ++ +IP + Q+ ++ T T + ++VV G + V +A ++C N+ DGT TV Y P+ G + + V ++ I GSPF K D ++ Q+ A ++ + L+ +++ PS E C+ + N +S+ P G++ + ++ KH+ SPF + GE + G ++E ++ NA + P+ + +C +++G +++ P E G +++N+ + +HIP SPF + V GE + + K + V TC + + LS E ++ + T T G V +S G GG P + E L I E + + TA V SP G+ EI+ ++ + +RF+P E+G HTV+VK HV GSPFQFTVGPL +GG HKV G+G+ER +A +F+I+TREAGAG LSIA+EGPSKAEI+F+D KDGSCGV+Y V EPGDY SIKFN+EH+P SPF++ P ++ S +D+R +++ +LQ++ + +A+F + +G G I A V +PS + ++++D+++ ++ F+P ENG+H++ V N S IPGSPF+V VGE G+ G+ G TG +EF V+T AG+GAL+VTIDGPSKV+++C E + GY +Y P APG+Y I IKYGG HI+GSPF + G S+ ET S +T++ M + S P + V C G GL A +G++N F VD AG ++L VGV GP PCE+V +KH+GN + V Y V+EKG ++++V+WG+ +PGSPF + P Sbjct: 1260 IKVYGPGVEPKGVLREVTTHFIVDARAHAKTKGGNHVKIRIINPSGANTDAYITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFKVSVVEGC-------DPTRVRAYGPGLE--GGIVNKPNCFTVETRGAGTAGLGLT---IEGASEAKMLC--KDNKDGSCSVEYMPFTAGDYDINIAYGGQPIPGSPFRVQVKDVVDVSKVKCSGPGLANKVTAHVPQTFTVDCSKAGVAPLEVQLYGPKGTLEPVVVKNNRDGTHTVNYTPAQEGPHTVSVKYANQEVPSSPYKVNSAPSHDASKVRASGPGLDTTGVAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKAS--IHDNRDGTYTVSYVPDMTGRYTITIKYGGDNIPYSPYNVQAFPTGDASKCLLTVSIGGHGVAESLGPNIQMSEETVITVDAKAAGKGKVTCTVQTPNGMELDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVMATDQPVAPRDDTK-PMFQPL----NLVIPFTVQQ---GELSGEVRMPSGKTARPFIRDNKDGTVTVQFQPTEKGLHEMDIKYDGNHIPGSPL---------QFYVDVTNSGMVTAYGPGLCHGTVNKPASFTVVTKNAGQGGLSLAVEGPSKAEISCKDNK----------DGTCTVSYLPTTPGDYNIIVKFDNSHIPGSPFTAKITGDDSLRRSQLNV----------GTAADVSLKITETDLSYLTASIKAPSGKEEPCLLKRLPNRHIGLSFTPKEVGEHEVSVRKSGKHVNNSPFKIMVGPSEIGEASRVKAFGKGLVEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDINC--DDVEDGTCKVTYCPTEPGNYIINIKFADKHIPGSPFTVKVTGEGRMKQSITRKRQAASI--ASVGSTCDLNLKIPGNWFQMLSAQ-ERLTRTFTRSSHTYTRTERTEISKTHGGETKREVHVEESTQVGGG-----GGDPFRDVFESFLGRDRLGSFGTIRQEGETGI-------QGMTAQVTSPGGNLADAEIVDSGNSTYRVRFVPTEMGSHTVNVKYRGEHVPGSPFQFTVGPLGEGGFHKVRAGGTGLERAVAKVPAEFSIWTREAGAGGLSIAVEGPSKAEINFEDRKDGSCGVSYVVQEPGDYEVSIKFNNEHIPDSPFIV-----PVATLS----------DDARRLTVTSLQEKDLKVNQEASFAVQRNG-ARGVIDAKVHAPSGVVEECYVTELDSDKNAIRFIPRENGVHSIDVKFNGSHIPGSPFKVRVGEAESVGDPGMVSAFGPGLEGGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEGYKISYTPMAPGNYLICIKYGGPQHIVGSPFKAKVIGMRLSGGHSLHETSSVIVETVTKSSKMAGAYSSLTSSMPTSDASKVVCHGAGLSKAFVGQKNSFSVDCSKAGTNMLMVGVHGPRTPCEDVTVKHMGNKLYNVTYTVKEKGNYVVIVKWGDETIPGSPFHVSAP 2702 HSP 4 Score: 438.343 bits (1126), Expect = 3.757e-123 Identity = 416/1546 (26.91%), Postives = 669/1546 (43.27%), Query Frame = 2 Query: 3164 IYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPM----EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFN------GKGIVKAIITNPFNQRSTCTV--DNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGI-TKQPQKFTVDLEGAGQGGLGLSIEGPADAQ--IQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVL---NSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSA------KNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYG--PGLSYGRPDMHAHFTIVTKDAGA-GGLSLAVEGPSKAEIQCI----DNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAK--IFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQ-----NGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSI--EGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTAS------VISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIG-SKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG----HTGRIN----EFFVDTSNAGNGALTVTIDGPSK--VQLNCQENESG-YNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIV 7618 + P Q +KA+ P + G ++K PA F +++ E + V +E P EAK+ ++ T SV Y+PK G + V VL+ + I SPF V + + + D KV A GPGL P G V KP F+ G G V +I +P N+ +T V +N D + C+Y P ++G H I +T+ G P+ SP+ V + + S+ + RA G GL+ +G+ K+ FTV +GAG G L +S++GP + ++ D DG Y P KPG Y V+I + + IP SPF V + KV+ +GPGL+ V + F V+A L ++ + ++ G DV Y P G+ + V+ ++ + SPF+ ++L N PEKV G G+ P + NK + FT++ R+AG+ L++ +++ + + GDGTF C Y P +T+ + +G N+P SPF V V P++ + GP + + + + V+ AG G +S VGP + I TV Y P G Y + ++F D+ IP+ + + + + I T +++ F G V N +I+N D + TV+Y G + V + G PI SPFK V ++ G+V G + G+ F + TK AG G +++++ PS I C K TC V Y+P G Y + I + + SPF+ + + +P K G + + ++ I+ A E +++ +G + + P E G++ +N+L HIP SPFK V +A +V G GL E F VD AG L++ I + ++ E+ +N DGT VTY P G + I +KY VP SP V + S T I + E + + I+ T +I+PSG+ I D + + + E G+H + V D V SPF+ +V D P +V G G+E G+ N N FT+ TR AG L + IEG S+A++ +DNKDGSC V Y GDY +I + + +PGSPF +Q ++ + A Q F + SKA + + P + + + ++V++ P + G H V V N +P SP++V + + G TG EF +D +AG G LTV I P + + +N G Y +YVP+ G YTI+IKYGG+N I SP+ V + + D+ + +++ H ++ S GP+ ++ + VDA AG + V P ++++ + F + Y E G++++ +R+G +P SPF+++ Sbjct: 275 VKPKQLYPKKAKAYGPGIEPQGNMVLK-----PAVFTVETLEAGLGEVIVYVEDPEGHTEEAKVVANNDKKRTFSVTYVPKVEGRHKVKVLFAGQDIDKSPFMVNV------AKALGDPNKVQARGPGLEPEG---------NVAHKPTYFDIYTAGAGAGDVSVVIVDPQNKNNTVEVILENKGDNIFRCTYKPVLEGPHTIHVTFAGQPIPSSPFKVNISEASNANACRATGRGLQPKGVRVKEVADFTVFTKGAGTGELKVSVKGPGGVEVPVKVCDVGDGVFKCDYCPVKPGKYTVNITWGGQPIPRSPFEVEVSKEAGTQKVRAWGPGLKTG--MVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIE----CDDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVKAFGPGLEPT--GVTVNK-STQFTVDAREAGKGGLKIYAQDAEGCVIDIQITDKGDGTFVCVYVPTKPVKHTIIITWGEVNIPKSPFRVLVGEGCHPDKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGPGRYTIMVVFADQEIPSSPFKVKVDPSHDAGKVRAEGPGINKTGVQVEIPTHFTI--FTKGAGKAKPEVHFKTAAKGNAVKDFEIIDNHDYSYTVKYTALHQGEMAIVVTHGGDPIPKSPFKITVAPSLDLGKVKVQGLNEKVEVGK---DQEFIVNTKGAGGQGKVNVSITSPSGRPIPCKLESDKTKEATC-VKYIPPEEGHYKVDITYDGNPVPESPFSVEGLMPADPSKVRAYGPGLKGGIVGQPAKFSIDTKGAGAGGLGLTLEGPCEAKIECQDNGDGTCSVVYLPTEAGDYNINILYGEAHIPGSPFKAVV--KPALDAGKVTASGPGLERAKAGEVASFTVDCSRAGEAELTIEIVSDSGAQAEVCIQNNKDGTFSVTYTPLFHGVHTITIKYGGQQVPKSPIHVKV---EPSVDTSGIKVYGPGVEPKGVLREVTTHFIVDARAHAKTKGGNHVKIRIINPSGANTDAYITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFKVSVVEGCD--PTRVRAYGPGLEGGIVNKPNCFTVETRGAGTAGLGLTIEGASEAKMLCKDNKDGSCSVEYMPFTAGDYDINIAYGGQPIPGSPFRVQ-------VKDVVDVSKVKCSGPGLANKVTAHVPQTFTVDCSKAGVA---------PLEVQLYGPKGTLEPVVVKNNRDGTHTVNYTPAQEGPHTVSVKYANQEVPSSPYKVNSAPSHDASKVRASGPGLDTTGVAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKASIHDNRDGTYTVSYVPDMTGRYTITIKYGGDN-IPYSPYNV----QAFPTGDASKCLLTVSIGGHGVAESL--GPN--------------IQMSEETVITVDAKAAGKGKVTCTVQTPNGMELDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVM 1741 HSP 5 Score: 224.557 bits (571), Expect = 6.913e-58 Identity = 190/602 (31.56%), Postives = 281/602 (46.68%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSK----VTASGPGI-EPVGN--EVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSK--TSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKK 2701 ++ +VRA GPGL+ G P FT+D +AGKG L + +L+P+G+ + I D N++ Y+ SY+P M G Y I IK+ IP SP+ V GD SK V+ G G+ E +G ++ T V AG G V C + G + + +T+ + F I YT E G + + + F G I SPF VM + + D K + QP + V F V +L V P + I+ + P G + +DIKY N I SP V + A+GPGL G V+KPA F V T N G L +++GPS+A+I C DN DG+ V+Y PT PG+Y + + D+ +IP SP+ A+I D D L+ + G + +S I T + +++KA +G+ P ++ + +TPK G+H V V ++ SPFK+ V E G A+ +K +G G+ A T F VD + AG G +G+S+ E V + DD DGT T Y I I F++ IP SPF V + + K+ Sbjct: 1546 DASKVRASGPGLDTTGVAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKASIHD--NRDGTYTVSYVPDMTGRYTITIKYGGDNIPYSPYNVQA-FPTGDASKCLLTVSIGGHGVAESLGPNIQMSEETVITVDAKAAGKGKVTCTVQTPNGME--LDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVMATDQPVAPRDDTKPMF------QPLNL----VIPFTVQQ-----GELSGEVRMPSGKTARPFIRDNKDGTVTVQFQPTEKGLHEMDIKYDGNHIPGSPLQFYVDVTNSGMVTAYGPGLCHGTVNKPASFTVVTKNAGQGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTTPGDYNIIVKFDNSHIPGSPFTAKITGD----DSLRRSQLNVGTAADVSLK-----ITETDLSYLTASIKAP----SGKEEPCLLKRLPNRHIGLSFTPKEVGEHEVSVRKSGKHVNNSPFKIMVGPSEIGEASRVKAFGKGLVEAHTFEVAEFFVDTRNAGYGGLGLSI--EGPSKVDINCDDVEDGT-CKVTYCPTEPGNYIINIKFADKHIPGSPFTVKVTGEGRMKQ 2111 HSP 6 Score: 132.88 bits (333), Expect = 4.739e-30 Identity = 138/501 (27.54%), Postives = 212/501 (42.32%), Query Frame = 2 Query: 1052 VLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKN-AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVI-------LDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDA-GFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE----SKIKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAV--------HILCDD------------------------ENIPKSPYMA----QIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTV------KAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVN 2386 V +P G EI DS N Y ++PT G + + +K+ +P SPF+ V G KV A G G+E +V F+++T EAG G + + ++ + RKD + Y +E G + V++ F I SPF V V+ T + DA++ T +Q + ++V A F V A G D V+ P +E+C + ++ +IP+ G + +D+K+ + I SPF V V + + AFGPGL GG P+ F V T +GAL +I GPS+ K+DC + +G ++Y P PG Y + HI+ E + KS MA + D KV +G GL K + F V+ AG+ + + C DVT ++ + Y+ YT K G + VIV +G+ IP SPF V+ Sbjct: 2230 VTSPGGNLADAEIVDSGNS--TYRVRFVPTEMGSHTVNVKYRGEHVPGSPFQFTVGPLGEGGFHKVRAGGTGLERAVAKVPAE--FSIWTREAGAGGLSIAVEGPSKAEINFEDRKD-----------GSCGVSYVVQEPGDYEVSIKFNNEHIPDSPFIVPVA--TLSDDARRLTVT--SLQEKDLKVNQEASFAVQRNGARGVID--AKVHAPSGVVEECYVTELDSDKNAIRFIPRENGVHSIDVKFNGSHIPGSPFKVRVGEAESVGDPGMVSAFGPGLEGGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEGY-KISYTPMAPGNYLICIKYGGPQHIVGSPFKAKVIGMRLSGGHSLHETSSVIVETVTKSSKMAGAYSSLTSSMPTSDASKVVCHGAGLSKAFVGQKNS-FSVDCSKAGTNMLMVGVHGPRTPCEDVT-------VKHMGNKLYNVTYTVKEKGNYVVIVKWGDETIPGSPFHVS 2700 HSP 7 Score: 117.857 bits (294), Expect = 1.493e-25 Identity = 124/426 (29.11%), Postives = 174/426 (40.85%), Query Frame = 2 Query: 941 RVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHL--SPFNVDVAPYK---------------------------------------ESKIKAFGPGLTGGIVSKPAFFEVE-TNGETGALGFSIKGPSEAKIDCVD-----NGDGSANVTYWPTVPGEYAVHILCDDENIPKSPY 2077 +VRA G GLE + PA F++ T AG G L I V P EI K+ + SY+ G+Y + IKF N IP+SPF V V + D ++T + ++ +V + F V G +D + G + +T+ +K I + +E G+HS++V F G I SPF V V S D A G G+ EG R +EF V+T AG L V + GP + C + Y+ SY P PG Y++ IKYG P H+ SPF V + SK+ G GL+ V + F V+ + T L + GP + C D G+ NVTY G Y V + DE IP SP+ Sbjct: 2292 KVRAGGTGLERAVAKV--PAEFSIWTREAGAGGLSIAVEGP----SKAEINFEDRKDGSCGVSYVVQEPGDYEVSIKFNNEHIPDSPFIVPVATLSDDARRLTVT--SLQEKDLKVNQEASFAV-QRNGARGVIDAKVHAPSGVVEEC--YVTELDSDKNAIRFIPRENGVHSIDVKFNGSHIPGSPFKVRVGEAESVGDPGMVSAFGPGL--EGGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEG---YKISYTPMAPGNYLICIKYG-GPQHIVGSPFKAKVIGMRLSGGHSLHETSSVIVETVTKSSKMAGAYSSLTSSMPTSDASKVVCHGAGLSKAFVGQKNSFSVDCSKAGTNMLMVGVHGP---RTPCEDVTVKHMGNKLYNVTYTVKEKGNYVVIVKWGDETIPGSPF 2697 HSP 8 Score: 90.8929 bits (224), Expect = 2.701e-17 Identity = 92/304 (30.26%), Postives = 129/304 (42.43%), Query Frame = 2 Query: 998 APFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNA--AGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVI-------LDTKGRKDSVKPKITKQSENKFLI-------------EYTTKEEG--------LHSVNVFFAGVQIQSSPFGVMVSSKTSN---SDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNV 1810 A F V N +G +D V P G E C + + + + A +IP G + I +KF S IP SPFKV V A GDP V+A GPG+E G G + F V T +AG G++ I +D ++ K T + +LI + K G LH + +SS SS TS+ SDA + G G+ V ++ F V AG L V V+GP E +K + LY +Y + G YVV +K+G+ I SPF+V Sbjct: 2403 ASFAVQR-NGARGVIDAKVHAPSGVVEECYVTELDSDKNA--IRFIPRENGVHSIDVKFNGSHIPGSPFKVRVGEAESVGDPGMVSAFGPGLE--GGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEGYKISYTPMAPGNYLICIKYGGPQHIVGSPFKAKVIGMRLSGGHSLHETSSVIVETVTKSSKMAGAYSSLTSSMPTSDASKVVCHGAGLSKAFVGQKN--SFSVDCSKAGTNMLMVGVHGPRTPCEDVTVKHMGNKLYNVTYTVKEKGNYVVIVKWGDETIPGSPFHV 2699
BLAST of Filamin vs. Ensembl Zebrafish
Match: flnca (filamin C, gamma a (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-070503-1]) HSP 1 Score: 1059.67 bits (2739), Expect = 0.000e+0 Identity = 767/2160 (35.51%), Postives = 1098/2160 (50.83%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKT-NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVS---------------SKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES---KIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNTTPIGQL-NEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV----------IATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIY---------PVQRTNEKAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQ-PQKFTVDLEGAG--QGG--LGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTP-GLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIV---PVHSEAKPEQCYIEGPILNEVPVGKT--VTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTH--HYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFK-FYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCI--DNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSP--FTAKIFGEPKKRSQ---ICVGTTSDVPLRISETDIN----NLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSS-SLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTV 6370 E++LAEDA WK IQ+NTFTRW N+HLK N + DLQ DL DGLKLI+L++ LS +R H RPNFR KLENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W+ ED D + K +PKQRLLGWI +K+P P+ NF DW DG A+GALVD CAPGLCP+W WDP Q ++NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L AP+ PK + +AYGPG+E +GN + PA FTV+T AG G + + V +P+G E ++ + +K+ +S +Y+P +EG +++ + FA +I SPF VNV A GDP+KV A GPG+EP GN + T+F+++TA AG G V VI+D + + ++V+ + + +N F Y EG H+++V FAG I SSPF V +S K S+A ATGRG+QP+GVRV++VA+F V T+ AG +L V+V GPG ++ V +++C Y P +PG Y V+I +G PI SPF V+V+ KE+ K++A+GPGL G+V K A F VE G E G LGFSI+GPS+AKI+C D GDGS +V YWPT PG+YAVH++CDDE+I SP+MA I P KV A+GPGL +G++ NK F V+ + AG +K D G I +QI D DGT+ C Y P P KHT+I+++G VNIP+SPF+V V E + +KVYGPG+E+ K N TYF VDC AG GD+ I + E D ++ +DN T YTI + F++ EIP SPFKV ++ +D K + +N T ++ F I T G K +PE+ K+ + +N + +T G + V G+PI SP+K+ + +N K + +++ A N SI S + P + + KT + P EE Y PV + E P V AYG GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV YLP E G Y +N+LY + HI SPF + P D KVTA GPGL + FTV+ + I+++ Q C + NN DGT+S +Y+P G H I I Y G V KSP V V D S I+ YGPG+E +G+ ++ F VD +GG + + I P+ A + D DGT V+Y + G + + + ++E +P SPF V + + D ++V+ YGPGLE G V P+ FTV+ AG A L + + + A++L K G V Y+P G+ +I + Y +PGSPF V + + KV +G G+ + + VP FT++ AG + LE+ + GP + V N+ DGT T Y G +TV V Y N+ VP SP+ V P H +K GP L+ V + V ++ ++AG G+L+ + + P G SI + R G TVSYVP G Y + + + +NIP AF + T + E P I+ V V V P+ + + N DGT + Y E G + + + + GQ I SPF+ D + T +P ++ G LS V PS + DNK+GT V + P G + + IK+ HI GSP F + + +C GT + P + N L+ V P+ E SC K ++G +S+ P G++ + V HIP SPF + ++ L LN G + + +T + Y L+ SI+ PS E C + H G +++ P E G + ++V+ + +V SPF + +G PS R+ + V E + S+ PS C+ + D + + P E G + +++K ++H+ GSPF V Sbjct: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKGVTDLQKDLGDGLKLISLLEVLSQKKMYRKHHVRPNFRQMKLENVSVALEFLDR-ERIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDDED----DEEVKKLTPKQRLLGWIQNKVPELPINNFNKDWRDGKALGALVDNCAPGLCPDWQTWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPVKPKQLYPKKAKAYGPGIEPQGNMVLKPAVFTVETLEAGLGEVIVYVEDPEGHTEEAKVVANNDKKRTFSVTYVPKVEGRHKVKVLFAGQDIDKSPFMVNVAKALGDPNKVQARGPGLEPEGNVAHKPTYFDIYTAGAGAGDVSVVIVDPQNKNNTVEVILENKGDNIFRCTYKPVLEGPHTIHVTFAGQPIPSSPFKVNISEAHLKPPGAPKQIPPQKKKASNANACRATGRGLQPKGVRVKEVADFTVFTKGAGTGELKVSVKGPGGVEVPVKVCDVGDGVFKCDYCPVKPGKYTVNITWGGQPIPRSPFEVEVS--KEAGTQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVKAFGPGLEPTGVTVNKSTQFTVDAREAGK-GGLKIYAQDAEGCVIDIQITDKGDGTFVCVYVPTKPVKHTIIITWGEVNIPKSPFRVLVGEGCHPDKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTV---KYTPPGPGRYTIMVVFADQEIPSSPFKVKVDPSHDAGKVRAEGPGINKTGVQVEIPTHFTIFTKGAG-KAKPEVHFKTAAKGNAVKDFEIIDNHDYSYTVKYTALHQGEMAIVVTHGGDPIPKSPFKITVAPSLDLGKVKVQGLNEKVEVGKDQEFIVNTKGAGGQGKVNV-SITSPSGRPIPCKLESDKT---KEATCVKYIPPEEGHYKVDITYDGNPVPESPFSVEGLMPADPSKVRAYGPGLKGGIVGQPAKFSIDTKGAGAGGLGLTLEGPCEAKIECQDNGDGTCSVVYLPTEAGDYNINILYGEAHIPGSPFKAVVKPAL-------DAGKVTASGPGLERAKA--GEVASFTVDCS--RAGEAELTIEIVSDSGAQAEVC-IQNNKDGTFSVTYTPLFHGVHTITIKYGGQQVPKSPIHVKVEPSVDTSGIKVYGPGVEPKGVLREVTTHFIVDARAHAKTKGGNHVKIRIINPSGANTDAYITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFKVSVVEGCDPTRVRAYGPGLE--GGIVNKPNCFTVETRGAGTAGLGLTI-----EGASEAKMLCKDNKDGSCSVEYMPFTAGDYDINIAYGGQPIPGSPFRVQVKDVVDVSKVKCSGPGL----ANKVTAHVPQTFTVDCSKAGVAPLEVQLYGPKGTLEPVVVKNNRDGTHTVNYTPAQEGPHTVSVKYANQEVPSSPYKVNSAPSHDASK---VRASGPGLDTTGVAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKASIHDNRDGTYTVSYVPDMTGRYTITIKYGGDNIPYSPYNVQAFPTGDASKCLLTVSIGGHGVESLGPNIQMSEETVITVDAKAAGKGKVTCTVQTPNGMELDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVMATDQPVAPRDDT---------KPMFQPLNLVIPFTVQQGELSGEVRMPSGKTARPFIRDNKDGTVTVQFQPTEKGLHEMDIKYDGNHIPGSPLQFYVDVTNSGMVTAYGPGLCHGTVNK-PASFTVVTKNAGQGGLSLAVEGPSKAEISC--KDNKDGTCTVSYLPTTPGDYNIIVKFDNSHIPGSPFTAKITGDD-------SLRRSQLNVGTAADVSLKITET-DLSY--LTASIKAPSGKEEPCLLKRLPNRHIG---LSFTPKEVGEHEVSVRKSGKHVNNSPFKIMVG--PSEIGEASRVKAFGKGLVEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDINCDDV--EDGTCKVTYCPTEPGNYIINIKFADKHIPGSPFTVKV 2120 HSP 2 Score: 1000.35 bits (2585), Expect = 0.000e+0 Identity = 762/2317 (32.89%), Postives = 1125/2317 (48.55%), Query Frame = 2 Query: 941 RVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNV-----------------KNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE----SKIKAFGPGL--TGGIVSKPAFFEVETNGETGALGFSIKGPSEA----KIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPS-TVKAECF-DVTGQT---IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE--TYFVVDCKLAGSGD----IGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQ--ETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV---IATDRVNTKEYPETETPLLIS--ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN-FEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKP-IDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--------VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPK-KRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPG------YNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSK--AEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIH----HGHTGRINE--FFVDTSNAGNGALTVTIDGPSKVQLNC--QENESGYN-FTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 +V+A GPGLE EGN P F + T AG G++ +++++P+ + E+ + + C+Y P +EG + I + FA IP+SPFKVN+ K A + + A+G G++P G V F VFT AG G + + G + VK + + F +Y + G ++VN+ + G I SPF V VS + + ++ A G G++ V A+F V LG ++ GP ++ +C K C + Y P PG Y V + + I SPF + P K+KAFGPGL TG V+K F V+ E G G I I D GDG+ Y PT P ++ + I + NIPKSP+ L + P KV YGPG+ +G+ N+P F V+ AG ++ +C V G I I N++ T++ +YTP PG++T++V + + IP SPFKV V + +A ++ GPGI + +E T+F + K AG + ++D ++ DN D ++T+KYT G + + IP+SPFK+ + D K K+ LN +G+ EF + T G + + + + SP+G +P KL+ +T + P G + V + GNP+ SP+ V + D + Y ++ A ++ID K L + ++ N + S + P E Y + + K L VTA G GL + A ASF +D + A L + I + +A++ +N DGT SV Y P G + + + Y + + SP +V + P D + + YGPG+ P GV ++ + F V+A+ G VK I NP + + + DGTY Y+ DG H I++ YD V V KSP+ V V +G DP+R+RAYGPGLE GI +P FTV+ GAG GLGL+IEG ++A++ C DNKDG+CSV+Y+P G YD++I + + IPGSPF V + D+VDVSKVKC GPGL N P FTVD SKAG APL+V + K ++ + G V Y P G + V Y N +VP SP+ N S + KV +G G+ +A +P FTI+ RDAG+ L + + P + + ++ DGT+T Y D+ G YT+ + YG N+P SP+ V +C + I + + + I V+ + AG G ++ P G + + G + Y + G Y + + F ++IP + A +Q R + +KP+ + V+ F G + VR PS + P + +N DGT+TVQ+QP+E GLHE+++ Y+G I GSP +FYVD T SG VTAYGPGL +G + A FT+VTK+AG GGLSLAVEGPSKAEI C DNK+GTC VSYLP PGDY+I +KF + HI GSPFTAKI G+ +RSQ+ VGT +DV L+I+ETD++ L A + +P+G+EE C LKRL N ++G+SFTPKEVGEH V+V +SG+H+ NSPFKI VG +EIG ASRVK +G GL + E +F VDTRNAGYGGL LSIEGPSKV+I C D DGTC VTY PTEPG YIIN+K+AD ++PGSPF V + G + + I R + AA ++ +G+ C+LNL IPG Q T + S ++ E +S + VH V + G PF+ + G ++ G+ + G E G ++ + P A+ + D+ + + V + E G + ++K+ EHVPGSPF + + K + + A F I G +S V PS E + + V +V E G + V + NN IP SPF V V ++ + ++N+ F N G + + PS V C E +S N ++P G ++I +K+ G +HI GSPF V + E +S+ P V G GL+ G +EF+V+ AG L V + GP + + N G ++++Y G +L+ +++G + GSPF+ V Sbjct: 384 KVQARGPGLEPEGNVAHKPTYFDIYTAGAGAGDVSVVIVDPQNKNNTVEVILENKGDNIFRCTYKPVLEGPHTIHVTFAGQPIPSSPFKVNISEAHLKPPGAPKQIPPQKKKASNANACRATGRGLQPKGVRVKEVADFTVFTKGAGTGELKVSVKGPGGVEVPVK--VCDVGDGVFKCDYCPVKPGKYTVNITWGGQPIPRSPFEVEVSKE---AGTQKVRAWGPGLKTG--MVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSC--DVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVKAFGPGLEPTGVTVNKSTQFTVDAR-EAGKGGLKIYAQDAEGCVIDIQITDKGDGTFVCVYVPTKPVKHTIIITWGEVNIPKSPFRV---LVGEGCHPDKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGPGRYTIMVVFADQEIPSSPFKVKVDPSHDAGKVRAEGPGINKTGVQVEIPTHFTIFTKGAGKAKPEVHFKTAAKGNAVKDFEII--DNHDYSYTVKYTALHQGEMAIV-VTHGGDPIPKSPFKITVAPSLDLGKVKVQGLNEKVEVGKDQEFIVNTKGAGGQGKVNVSITSPSGRPIPCKLESDKTKEATCVKYIPPEEGHYKVDITYDGNPVPESPFSVEGLMPADPSKVRAYGPGLKGGIVGQPAKFSIDTKGAGAGG---LGLTLEGPCEAKIECQDNGDGTCSVVYLPTEAGDYNINILYGEAHIPGSPFKAVVKPALDAGKVTASGPGLERAKAGEVASFTVDCSRAGEAELTIEIVSDSGAQAEVCIQNNKDGTFSVTYTPLFHGVHTITIKYGGQQVPKSPIHVKVEPSV-------DTSGIKVYGPGVEPKGVLREVTTHFIVDARAHAKTKGGNHVKIRIINPSGANTDAYITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFKVSVVEGCDPTRVRAYGPGLEGGIVNKPNCFTVETRGAGTAGLGLTIEGASEAKMLCKDNKDGSCSVEYMPFTAGDYDINIAYGGQPIPGSPFRVQVKDVVDVSKVKCSGPGLA-NKVTAHVPQTFTVDCSKAGVAPLEVQLY--GPKGTLEPVVVKNNRDGTHTVNYTPAQEGPHTVSVKYANQEVPSSPYKVNSAPSHDASKVRASGPGLDTTG---VAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKASIHDNRDGTYTVSYVPDMTGRYTITIKYGGDNIPYSPYNVQAFPTGDASKCLLTVSIGGHGVESLGPNIQMSEETVITVDAKAAGKGKVTCTVQTPNGMELDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVMA---TDQPVAPR-------DDTKPMFQPLNLVIPFTVQQGELSGEVRM----PSGKTARPFIRDNKDGTVTVQFQPTEKGLHEMDIKYDGNHIPGSPLQFYVDVT-NSGMVTAYGPGLCHGTVNKPASFTVVTKNAGQGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTTPGDYNIIVKFDNSHIPGSPFTAKITGDDSLRRSQLNVGTAADVSLKITETDLSYLTASIKAPSGKEEPCLLKRLPNRHIGLSFTPKEVGEHEVSVRKSGKHVNNSPFKIMVGPSEIGEASRVKAFGKGLVEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDINCDDVEDGTCKVTYCPTEPGNYIINIKFADKHIPGSPFTVKVTG--EGRMKQSITRKRQAASIASVGSTCDLNLKIPGNWFQMLSAQERLTRTFTRSSHTYTRTERTEISKTHGG----ETKREVH-VEESTQVGGGGGDPFRDVFESFL--GRDRLGSFGTIRQEG-------------ETGIQGMTAQVTSPGGNLADAEIVDSGNSTYRVRFVPTEMGSHTVNVKYRGEHVPGSPFQFTVGPLGEGGFHK--------------VRAGGTGLERAVAKVPAEFSIWTREAGAGGLSIAVEGPSKAE--INFEDRKDGSCGVSYVVQEPGDYEVSIKFNNEHIPDSPFIVPVATLSDDARRLTVTSLQEKDLKVNQEASFAVQRNGARGVIDAKVHAPSGVVEECYVTELDSDKNAIRFIPRENGVHSIDVKFNG-SHIPGSPFKVRVG-----------EAESV---------------GDPGMVSAFGPGLEGGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEG---YKISYTPMAPGNYLICIKYGGPQHIVGSPFKAKV 2585 HSP 3 Score: 639.802 bits (1649), Expect = 0.000e+0 Identity = 478/1529 (31.26%), Postives = 741/1529 (48.46%), Query Frame = 2 Query: 3215 VTAYGEGLV-KGVANTPAS-FIIDSTEEPPAPLG----VTIEGPMEAKID-YI-DNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQ-PQKFTVDLEGAGQGGLGLSIEGPADAQ--IQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVT----GEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIR------TEYSVVDFKFPVGPVFDYV----RAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPF--KFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNK--NGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKI----FGEPKKRSQICVGTTSDVPLRISETDINNLNA-------IVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFV-GENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXX---------XIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-----LTQTVHMISGSTQKGPSKPYN----VKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 + YG G+ KGV + FI+D+ G + I P A D YI D GDGT V Y E G +++ V Y++ + SPF V++ D +V AYGPGL G + + FTV + G G+ I + C +N DG+ S Y P G + I+I Y G P+ SP+ V V D S+++ GPGL +T PQ FTVD AG L + + GP + +N+DGT +V Y P + G + VS+K+ + +P SP+ V D SKV+ GPGL+ G P +FT+DA AG+ L V ++D K K + + + G + V+Y+P+ G I + Y +P SP+ + + K ++T G GV G I ++ T++ + AG+ + V PN +++DV + DGTF Y PG Y + + +G +++P SPF V + + + P+ + + IP Q G LS + P G I + + G TV + P + G +E+ + ++ +IP + Q+ ++ T T + ++VV G + V +A ++C N+ DGT TV Y P+ G + + V ++ I GSPF K D ++ Q+ A ++ + L+ +++ PS E C+ + N +S+ P G++ + ++ KH+ SPF + GE + G ++E ++ NA + P+ + +C +++G +++ P E G +++N+ + +HIP SPF + V GE + + K + V TC + + LS E ++ + T T G V +S G GG P + E L I E + + TA V SP G+ EI+ ++ + +RF+P E+G HTV+VK HV GSPFQFTVGPL +GG HKV G+G+ER +A +F+I+TREAGAG LSIA+EGPSKAEI+F+D KDGSCGV+Y V EPGDY SIKFN+EH+P SPF++ P ++ S +D+R +++ +LQ++ + +A+F + +G G I A V +PS + ++++D+++ ++ F+P ENG+H++ V N S IPGSPF+V VGE G+ G+ G TG +EF V+T AG+GAL+VTIDGPSKV+++C E + GY +Y P APG+Y I IKYGG HI+GSPF + G S+ ET S +T++ M + S P + V C G GL A +G++N F VD AG ++L VGV GP PCE+V +KH+GN + V Y V+EKG ++++V+WG+ +PGSPF + P Sbjct: 1278 IKVYGPGVEPKGVLREVTTHFIVDARAHAKTKGGNHVKIRIINPSGANTDAYITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFKVSVVEGC-------DPTRVRAYGPGLE--GGIVNKPNCFTVETRGAGTAGLGLT---IEGASEAKMLC--KDNKDGSCSVEYMPFTAGDYDINIAYGGQPIPGSPFRVQVKDVVDVSKVKCSGPGLANKVTAHVPQTFTVDCSKAGVAPLEVQLYGPKGTLEPVVVKNNRDGTHTVNYTPAQEGPHTVSVKYANQEVPSSPYKVNSAPSHDASKVRASGPGLDTTGVAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKAS--IHDNRDGTYTVSYVPDMTGRYTITIKYGGDNIPYSPYNVQAFPTGDASKCLLTVSIGGHGVE-SLGPNIQMSEETVITVDAKAAGKGKVTCTVQTPNGMELDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVMATDQPVAPRDDTK-PMFQPL----NLVIPFTVQQ---GELSGEVRMPSGKTARPFIRDNKDGTVTVQFQPTEKGLHEMDIKYDGNHIPGSPL---------QFYVDVTNSGMVTAYGPGLCHGTVNKPASFTVVTKNAGQGGLSLAVEGPSKAEISCKDNK----------DGTCTVSYLPTTPGDYNIIVKFDNSHIPGSPFTAKITGDDSLRRSQLNV----------GTAADVSLKITETDLSYLTASIKAPSGKEEPCLLKRLPNRHIGLSFTPKEVGEHEVSVRKSGKHVNNSPFKIMVGPSEIGEASRVKAFGKGLVEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDINC--DDVEDGTCKVTYCPTEPGNYIINIKFADKHIPGSPFTVKVTGEGRMKQSITRKRQAASI--ASVGSTCDLNLKIPGNWFQMLSAQ-ERLTRTFTRSSHTYTRTERTEISKTHGGETKREVHVEESTQVGGG-----GGDPFRDVFESFLGRDRLGSFGTIRQEGETGI-------QGMTAQVTSPGGNLADAEIVDSGNSTYRVRFVPTEMGSHTVNVKYRGEHVPGSPFQFTVGPLGEGGFHKVRAGGTGLERAVAKVPAEFSIWTREAGAGGLSIAVEGPSKAEINFEDRKDGSCGVSYVVQEPGDYEVSIKFNNEHIPDSPFIV-----PVATLS----------DDARRLTVTSLQEKDLKVNQEASFAVQRNG-ARGVIDAKVHAPSGVVEECYVTELDSDKNAIRFIPRENGVHSIDVKFNGSHIPGSPFKVRVGEAESVGDPGMVSAFGPGLEGGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEGYKISYTPMAPGNYLICIKYGGPQHIVGSPFKAKVIGMRLSGGHSLHETSSVIVETVTKSSKMAGAYSSLTSSMPTSDASKVVCHGAGLSKAFVGQKNSFSVDCSKAGTNMLMVGVHGPRTPCEDVTVKHMGNKLYNVTYTVKEKGNYVVIVKWGDETIPGSPFHVSAP 2719 HSP 4 Score: 427.943 bits (1099), Expect = 6.946e-120 Identity = 417/1564 (26.66%), Postives = 664/1564 (42.46%), Query Frame = 2 Query: 3164 IYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPM----EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFN------GKGIVKAIITNPFNQRSTCTV--DNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQ------------------GSDPSRIRAYGPGLE-EGI-TKQPQKFTVDLEGAGQGGLGLSIEGPADAQ--IQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVL---NSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSA------KNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYG--PGLSYGRPDMHAHFTIVTKDAGA-GGLSLAVEGPSKAEIQCI----DNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAK--IFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQ-----NGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSI--EGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTAS------VISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIG-SKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG----HTGRIN----EFFVDTSNAGNGALTVTIDGPSK--VQLNCQENESG-YNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIV 7618 + P Q +KA+ P + G ++K PA F +++ E + V +E P EAK+ ++ T SV Y+PK G + V VL+ + I SPF V + + + D KV A GPGL P G V KP F+ G G V +I +P N+ +T V +N D + C+Y P ++G H I +T+ G P+ SP+ V + + S+ + RA G GL+ +G+ K+ FTV +GAG G L +S++GP + ++ D DG Y P KPG Y V+I + + IP SPF V + KV+ +GPGL+ V + F V+A L ++ + ++ G DV Y P G+ + V+ ++ + SPF+ ++L N PEKV G G+ P + NK + FT++ R+AG+ L++ +++ + + GDGTF C Y P +T+ + +G N+P SPF V V P++ + GP + + + + V+ AG G +S VGP + I TV Y P G Y + ++F D+ IP+ + + + + I T +++ F G V N +I+N D + TV+Y G + V + G PI SPFK V ++ G+V G + G+ F + TK AG G +++++ PS I C K TC V Y+P G Y + I + + SPF+ + + +P K G + + ++ I+ A E +++ +G + + P E G++ +N+L HIP SPFK V +A +V G GL E F VD AG L++ I + ++ E+ +N DGT VTY P G + I +KY VP SP V + S T I + E + + I+ T +I+PSG+ I D + + + E G+H + V D V SPF+ +V D P +V G G+E G+ N N FT+ TR AG L + IEG S+A++ +DNKDGSC V Y GDY +I + + +PGSPF +Q ++ + A Q F + SKA + + P + + + ++V++ P + G H V V N +P SP++V + + G TG EF +D +AG G LTV I P + + +N G Y +YVP+ G YTI+IKYGG+N I SP+ N Q+ + +K L G GP+ ++ + VDA AG + V P ++++ + F + Y E G++++ +R+G +P SPF+++ Sbjct: 275 VKPKQLYPKKAKAYGPGIEPQGNMVLK-----PAVFTVETLEAGLGEVIVYVEDPEGHTEEAKVVANNDKKRTFSVTYVPKVEGRHKVKVLFAGQDIDKSPFMVNV------AKALGDPNKVQARGPGLEPEG---------NVAHKPTYFDIYTAGAGAGDVSVVIVDPQNKNNTVEVILENKGDNIFRCTYKPVLEGPHTIHVTFAGQPIPSSPFKVNISEAHLKPPGAPKQIPPQKKKASNANACRATGRGLQPKGVRVKEVADFTVFTKGAGTGELKVSVKGPGGVEVPVKVCDVGDGVFKCDYCPVKPGKYTVNITWGGQPIPRSPFEVEVSKEAGTQKVRAWGPGLKTG--MVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIE----CDDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVKAFGPGLEPT--GVTVNK-STQFTVDAREAGKGGLKIYAQDAEGCVIDIQITDKGDGTFVCVYVPTKPVKHTIIITWGEVNIPKSPFRVLVGEGCHPDKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGPGRYTIMVVFADQEIPSSPFKVKVDPSHDAGKVRAEGPGINKTGVQVEIPTHFTI--FTKGAGKAKPEVHFKTAAKGNAVKDFEIIDNHDYSYTVKYTALHQGEMAIVVTHGGDPIPKSPFKITVAPSLDLGKVKVQGLNEKVEVGK---DQEFIVNTKGAGGQGKVNVSITSPSGRPIPCKLESDKTKEATC-VKYIPPEEGHYKVDITYDGNPVPESPFSVEGLMPADPSKVRAYGPGLKGGIVGQPAKFSIDTKGAGAGGLGLTLEGPCEAKIECQDNGDGTCSVVYLPTEAGDYNINILYGEAHIPGSPFKAVV--KPALDAGKVTASGPGLERAKAGEVASFTVDCSRAGEAELTIEIVSDSGAQAEVCIQNNKDGTFSVTYTPLFHGVHTITIKYGGQQVPKSPIHVKV---EPSVDTSGIKVYGPGVEPKGVLREVTTHFIVDARAHAKTKGGNHVKIRIINPSGANTDAYITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFKVSVVEGCD--PTRVRAYGPGLEGGIVNKPNCFTVETRGAGTAGLGLTIEGASEAKMLCKDNKDGSCSVEYMPFTAGDYDINIAYGGQPIPGSPFRVQ-------VKDVVDVSKVKCSGPGLANKVTAHVPQTFTVDCSKAGVA---------PLEVQLYGPKGTLEPVVVKNNRDGTHTVNYTPAQEGPHTVSVKYANQEVPSSPYKVNSAPSHDASKVRASGPGLDTTGVAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKASIHDNRDGTYTVSYVPDMTGRYTITIKYGGDN-IPYSPY-------NVQAFPTGDASKCLLTVSIGGHGVESLGPN--------------IQMSEETVITVDAKAAGKGKVTCTVQTPNGMELDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVM 1758 HSP 5 Score: 229.565 bits (584), Expect = 2.373e-59 Identity = 189/599 (31.55%), Postives = 279/599 (46.58%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSK----VTASGPGIEPVGN--EVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKK 2701 ++ +VRA GPGL+ G P FT+D +AGKG L + +L+P+G+ + I D N++ Y+ SY+P M G Y I IK+ IP SP+ V GD SK V+ G G+E +G ++ T V AG G V C + G + + +T+ + F I YT E G + + + F G I SPF VM + Q A +P + V F V +L V P + I+ + P G + +DIKY N I SP V + A+GPGL G V+KPA F V T N G L +++GPS+A+I C DN DG+ V+Y PT PG+Y + + D+ +IP SP+ A+I D D L+ + G + +S I T + +++KA +G+ P ++ + +TPK G+H V V ++ SPFK+ V E G A+ +K +G G+ A T F VD + AG G +G+S+ E V + DD DGT T Y I I F++ IP SPF V + + K+ Sbjct: 1564 DASKVRASGPGLDTTGVAASLPVEFTIDARDAGKGLLTVQILDPEGKPKKASIHD--NRDGTYTVSYVPDMTGRYTITIKYGGDNIPYSPYNVQA-FPTGDASKCLLTVSIGGHGVESLGPNIQMSEETVITVDAKAAGKGKVTCTVQTPNGME--LDMDVTENPDGTFDIYYTAPEPGKYVITIRFGGQHIPKSPFQVMATD--------QPVAPRDDTKPMFQPLNLVIPFTVQQ-----GELSGEVRMPSGKTARPFIRDNKDGTVTVQFQPTEKGLHEMDIKYDGNHIPGSPLQFYVDVTNSGMVTAYGPGLCHGTVNKPASFTVVTKNAGQGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTTPGDYNIIVKFDNSHIPGSPFTAKITGD----DSLRRSQLNVGTAADVSLK-----ITETDLSYLTASIKAP----SGKEEPCLLKRLPNRHIGLSFTPKEVGEHEVSVRKSGKHVNNSPFKIMVGPSEIGEASRVKAFGKGLVEAHTFEVAEFFVDTRNAGYGGLGLSI--EGPSKVDINCDDVEDGTC-KVTYCPTEPGNYIINIKFADKHIPGSPFTVKVTGEGRMKQ 2128 HSP 6 Score: 132.88 bits (333), Expect = 4.708e-30 Identity = 138/501 (27.54%), Postives = 212/501 (42.32%), Query Frame = 2 Query: 1052 VLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKN-AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVI-------LDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDA-GFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE----SKIKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAV--------HILCDD------------------------ENIPKSPYMA----QIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTV------KAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVN 2386 V +P G EI DS N Y ++PT G + + +K+ +P SPF+ V G KV A G G+E +V F+++T EAG G + + ++ + RKD + Y +E G + V++ F I SPF V V+ T + DA++ T +Q + ++V A F V A G D V+ P +E+C + ++ +IP+ G + +D+K+ + I SPF V V + + AFGPGL GG P+ F V T +GAL +I GPS+ K+DC + +G ++Y P PG Y + HI+ E + KS MA + D KV +G GL K + F V+ AG+ + + C DVT ++ + Y+ YT K G + VIV +G+ IP SPF V+ Sbjct: 2247 VTSPGGNLADAEIVDSGNS--TYRVRFVPTEMGSHTVNVKYRGEHVPGSPFQFTVGPLGEGGFHKVRAGGTGLERAVAKVPAE--FSIWTREAGAGGLSIAVEGPSKAEINFEDRKD-----------GSCGVSYVVQEPGDYEVSIKFNNEHIPDSPFIVPVA--TLSDDARRLTVT--SLQEKDLKVNQEASFAVQRNGARGVID--AKVHAPSGVVEECYVTELDSDKNAIRFIPRENGVHSIDVKFNGSHIPGSPFKVRVGEAESVGDPGMVSAFGPGLEGGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEGY-KISYTPMAPGNYLICIKYGGPQHIVGSPFKAKVIGMRLSGGHSLHETSSVIVETVTKSSKMAGAYSSLTSSMPTSDASKVVCHGAGLSKAFVGQKNS-FSVDCSKAGTNMLMVGVHGPRTPCEDVT-------VKHMGNKLYNVTYTVKEKGNYVVIVKWGDETIPGSPFHVS 2717 HSP 7 Score: 118.242 bits (295), Expect = 1.297e-25 Identity = 124/426 (29.11%), Postives = 174/426 (40.85%), Query Frame = 2 Query: 941 RVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHL--SPFNVDVAPYK---------------------------------------ESKIKAFGPGLTGGIVSKPAFFEVE-TNGETGALGFSIKGPSEAKIDCVD-----NGDGSANVTYWPTVPGEYAVHILCDDENIPKSPY 2077 +VRA G GLE + PA F++ T AG G L I V P EI K+ + SY+ G+Y + IKF N IP+SPF V V + D ++T + ++ +V + F V G +D + G + +T+ +K I + +E G+HS++V F G I SPF V V S D A G G+ EG R +EF V+T AG L V + GP + C + Y+ SY P PG Y++ IKYG P H+ SPF V + SK+ G GL+ V + F V+ + T L + GP + C D G+ NVTY G Y V + DE IP SP+ Sbjct: 2309 KVRAGGTGLERAVAKV--PAEFSIWTREAGAGGLSIAVEGP----SKAEINFEDRKDGSCGVSYVVQEPGDYEVSIKFNNEHIPDSPFIVPVATLSDDARRLTVT--SLQEKDLKVNQEASFAV-QRNGARGVIDAKVHAPSGVVEEC--YVTELDSDKNAIRFIPRENGVHSIDVKFNGSHIPGSPFKVRVGEAESVGDPGMVSAFGPGL--EGGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEG---YKISYTPMAPGNYLICIKYG-GPQHIVGSPFKAKVIGMRLSGGHSLHETSSVIVETVTKSSKMAGAYSSLTSSMPTSDASKVVCHGAGLSKAFVGQKNSFSVDCSKAGTNMLMVGVHGP---RTPCEDVTVKHMGNKLYNVTYTVKEKGNYVVIVKWGDETIPGSPF 2714 HSP 8 Score: 90.8929 bits (224), Expect = 2.704e-17 Identity = 92/304 (30.26%), Postives = 129/304 (42.43%), Query Frame = 2 Query: 998 APFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNA--AGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVI-------LDTKGRKDSVKPKITKQSENKFLI-------------EYTTKEEG--------LHSVNVFFAGVQIQSSPFGVMVSSKTSN---SDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNV 1810 A F V N +G +D V P G E C + + + + A +IP G + I +KF S IP SPFKV V A GDP V+A GPG+E G G + F V T +AG G++ I +D ++ K T + +LI + K G LH + +SS SS TS+ SDA + G G+ V ++ F V AG L V V+GP E +K + LY +Y + G YVV +K+G+ I SPF+V Sbjct: 2420 ASFAVQR-NGARGVIDAKVHAPSGVVEECYVTELDSDKNA--IRFIPRENGVHSIDVKFNGSHIPGSPFKVRVGEAESVGDPGMVSAFGPGLE--GGRTGVPSEFVVNTCKAGSGALSVTIDGPSKVKMDCNECQEGYKISYTPMAPGNYLICIKYGGPQHIVGSPFKAKVIGMRLSGGHSLHETSSVIVETVTKSSKMAGAYSSLTSSMPTSDASKVVCHGAGLSKAFVGQKN--SFSVDCSKAGTNMLMVGVHGPRTPCEDVTVKHMGNKLYNVTYTVKEKGNYVVIVKWGDETIPGSPFHV 2716 HSP 9 Score: 60.8474 bits (146), Expect = 2.759e-8 Identity = 76/310 (24.52%), Postives = 124/310 (40.00%), Query Frame = 2 Query: 6740 ALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQ--YSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTGRINE---------FFVDTSNAGNGALTVTIDGPSKVQLNCQ---ENESG--YNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 ++ QG + A F + G + YV P + A + ++ + +SV +VP G H V VL I SPF V V + + G E F + T+ AG G ++V I P + EN+ + TY P G +TI + + G I SPF V IS + + + ++ + + G + G++V E+ +F V AG L V V GP V + +G+ F+ +Y + G++ + + WG +P SPFE+ V Sbjct: 291 GIEPQGNMVLKPAVFTVETLEAGLGEVIVYVEDPEGHTEEAKVVANNDKKRTFSVTYVPKVEGRHKVKVLFAGQDIDKSPFMVNVAKALGDPNKVQARGPGLEPEGNVAHKPTYFDIYTAGAGAGDVSVVIVDPQNKNNTVEVILENKGDNIFRCTYKPVLEGPHTIHVTFAGQP-IPSSPFKVNISEAHLKPPGAPKQIPPQKKKASNANACRATGRG------LQPKGVRVKEVA---DFTVFTKGAGTGELKVSVKGPGGVEVPVKVCDVGDGVFKCDYCPVKPGKYTVNITWGGQPIPRSPFEVEV 590
BLAST of Filamin vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165]) HSP 1 Score: 1734.92 bits (4492), Expect = 0.000e+0 Identity = 1053/2625 (40.11%), Postives = 1497/2625 (57.03%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVA-PYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS------VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINN---LNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYK--VIATDRVNTKEYPETETPLLISAD--YAID-NKAYNKPSIPVQSAKLTPVERSNVKTFSNP----NKQRSNFEPNEEIIY---------PVQRTNEKAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNID---DVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEE-GITKQP-QKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVN----TQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIR-------------------QYAFQPQEQ--YSIERTTH-------------------------------HYTTEQSKP-IIRTEYSVVD-----FKFPVGPVFDYVRAVV-------------NCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXX---------XXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGSTQ-----KGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 + E++LA+DA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS +R H+RP F +LENV++ L FLE E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+WE ++ D + K +PKQRLLGWI +K+P P+ NF+ +W DG A+GALVD+CAPGLCP+W WDPK+ ++NA+EA+ A++ L V +I P E+I+P VDE ++MTYLSQFP A+L APL PK N + RAYG G+E GN + APFTV+T +AG G + + + +P+G +E ++ + +K +S Y+P + G +++ + FA I SPF+VNV+ A GD SKVTA GPG+EP+GN + T+F+++TA AG G + ++D +GR ++V+ + + + Y + G H+V + F G SP+ V + + N +A A GRG+QP+GVR+R+ A+F+V T+ AG DL V+V GP E + + L+ Y P PG YVV I +G + I SPF V VA K++A+GPGL G+ K A F VE+ G E G+LGF+I+GPS+AKI+C D GDGS +V YWP PGEYA+HI+CDDE+I SPYMA IQ + DP KV AYGPGL +G + PA+F V+ +AG + +K DV G + + ++ DGTY+C YTP P KHTV V++G V++P SPF+VN+ + + +KV+GPG+E+ K N T+F VDC AG GD+ + V+ ++ D+ N + TF YTI++ F+ EIP+SPF++ ++ +D K + + G+ + F + T G K ++ P + +N +TP G V V G+PI SP+ V A +N E+ + + D + +D N A + + V K++ R +V P + P EE +Y PV + E P V AYG GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP PG Y VN+L+ + HI SPF +N++ D +KV A GPGL V + + G G + + ++ V +N DGTY+ +Y P G + + + Y G V K P V V D S+I+ +GPG+EE G+ ++ FTVD L G + I P+ A DN DGT V+Y P + G++ + + ++++ +P SPF V + + +VK G GL + P+ F+V AG L + V + + + G V Y P G+ ++ + Y+ +PGSPF V + +P KV ++G G+ G + K+P FT++T AG + L + VTGP +D+ ++GDGT T Y + G YTV V Y ++ +P SPF V V + GP L G + ++PVN +NAG G LS + G I++ G +VSY+P + G Y V + + ++IP R Q A + E+ + ++ TT +YTT ++ P +I + D F P F V+ + PS + +++N DGT++++Y P+E+GLHEL + NG I SP +F+V+ +G V+AYGPGL YG + A FTI+T+DAG GGL LA+EGPSKAEI CIDNK+GTC V+YLP PGDY+I +K+ D HI GSPF AKI + ++RSQ+ +G+T+D L I+ETD++ L+A + +P+GR+E C LKRL N ++GISF P+EVGEHLV++ ++GRHIPNSP I V ++EIG+AS+VK +G GL +G E F+VDTR AGYGGLSL++EGPSKV+I+ D DGTC V+Y PTEPG YI+++K+AD +VPGSPF + G + E I R + A V+ +G +CELNL IP ++ TA V+SPSG + EI+ L N +RF+P+E G+HTVSVK HV GSPFQFTVGPL +GG KV G G+ERG A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGS GV+Y V EPGDY IKFNDEH+P SPF++ I +D+R +++ +LQ+ G + A+F I +G G I A V SPS + +++++ ++Y+V F+P ENGIH + V N S +PGSPF+V VGE T G+G+ G TG+ +EF ++TS AG GAL+VTI+GPSKV + C+E GY Y P APG Y I +KYGG NHI+GSPF ++G ET S + Q+V S T + S V +G GL A +G+++ F VD AG ++L VGV GP PCEEV+IKHLGN + V+Y+V+E+G ++L+V+WG +PGSPF I VP Sbjct: 3 VTEKDLAQDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFSQMQLENVSVALEFLER-ENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWE----DEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGLGVEPTGNMVKRSAPFTVETISAGTGEVLVYIEDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFAGQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSI-GEACNPNA--CRANGRGLQPKGVRIRETADFRVDTKAAGSGDLHVSVKGPKGLDEVLKQSESLDGLHLFEYYPLTPGKYVVAITWGGHHIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYGPGLEKTGCIVSTPAEFAVDPTDAGK-AALKIYSQDVEGNPVDIMTKEKPDGTYACSYTPAKPIKHTVAVTWGGVSVPNSPFRVNIGQGSHPHLVKVFGPGVEKTGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVISDEEEDIDFDIIPNANDTF-TVKYMPPAAGRYTIKVLFAGEEIPESPFRIKVDPSHDASKVRAEGPGLSKSGVENGKPSHFTVYTKGAG-KAPVDVSFTGPAPGDAVKDFEIIDNYDYSHTVRYTPVQQGKMKVAVNYGGDPIPKSPFTVGVAAPLDLNKIRINGLESRVEVGKDQQFIVDPNGAGGQGKLEV---KISSPSRKSVPCLVEPVPGNECSTVKYIPKEEGLYNVDVSYDGNPVPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPFQ----------ANVEMPFDPSKVIATGPGLEHGKVGEAGLIHVDCSQA-----GPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKIKVFGPGIEEKGVFREATTDFTVDAKSLTKTGGNHVKTKITNPSGASTDYLLRDNGDGTYYVEYTPFEKGAHAIKVTYDDEPVPNSPFKVGVTEGCYPDRVKAQGAGLTE--ALTNKPNLFSVITRGAGIGGLGITVEGPSESKMS----CKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGL----GTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRGTVEPVDLVDNGDGTHTVSYTPTLEGPYTVAVQYADEEIPRSPFKVKVLPTYDASKVTASGPGL--CAQGISASLPVNFAVDAKNAGLGPLSVQITDQEGKPKKAQIQDNNDGTYSVSYIPDRTGRYHVAVKYGGDDIPYSPYRIRAMSIGDASKCTVAGPGIQAAVKTGEEVGFVVDATTAGKGKVTCSILGPDGLENEADVIENVDGTYDIYYTTAKTGPYVIHVRFGGADIPNSPFTVMGAPCFRPFDLVIPFAIRTGEITGDVHMPSGKTAPADIVDNKDGTVSIRYVPTETGLHELAIKCNGAHIPESPLQFFVNYP-NTGSVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITDDSRRRSQVKLGSTADFLLDITETDLSLLSASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMG--EGRVKESITRRRKAPSVASVGGLCELNLKIPEIDRNELTAEVVSPSGRKQEAEIVDLGQNTSCVRFVPQETGIHTVSVKYRGEHVPGSPFQFTVGPLGEGGAEKVKAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATS---------------DDARRLTVTSLQESGLKVNQPASFAIRLNG-ARGKIDAKVHSPSGAVEECFVTELEPDKYAVRFMPRENGIHMIDVKFNGSHVPGSPFKVRVGEAGQEGDPGLVTAYGDGLETGTTGKQSEFIINTSKAGPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFKAKVTGQRLVGIGGTSETSSIIVQSVTRASTETTYSALPRFASDATKVTSKGAGLSKAFLGQKSTFTVDCSKAGSNILLVGVHGPTLPCEEVSIKHLGNKHYTVHYHVKERGDYMLVVKWGEEHIPGSPFHITVP 2567
BLAST of Filamin vs. Ensembl Xenopus
Match: FLNB (filamin B [Source:NCBI gene;Acc:100485165]) HSP 1 Score: 1556.96 bits (4030), Expect = 0.000e+0 Identity = 1001/2626 (38.12%), Postives = 1429/2626 (54.42%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVA-PYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS------VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINN---LNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYK--VIATDRVNTKEYPETETPLLISAD--YAID-NKAYNKPSIPVQSAKLTPVERSNVKTFSNP----NKQRSNFEPNEEIIY---------PVQRTNEKAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNID---DVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEE-GITKQP-QKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVN----TQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE--YSVVDFKFPVGPVFDYVRA---VVNC----PSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIP--------SGQVTAYGP--------------GLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFT----------------AKIFGEPKKRSQICVGTTS----------DVPLRISETDINNLNA---IVISPTGREESCTLKRLQNGYL----------GISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXX---------XXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGSTQ-----KGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 + E++LA+DA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS +R H+RP F +LENV++ L FLE E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+WE ++ D + K +PKQRLLGWI +K+P P+ NF+ +W DG A+GALVD+CAPGLCP+W WDPK+ ++NA+EA+ A++ L V +I P E+I+P VDE ++MTYLSQFP A+L APL PK N + RAYG G+E GN + APFTV+T +AG G + + + +P+G +E ++ + +K +S Y+P + G +++ + FA I SPF+VNV+ A GD SKVTA GPG+EP+GN + T+F+++TA AG G + ++D +GR ++V+ + + + Y + G H+V + F G SP+ V + + N +A A GRG+QP+GVR+R+ A+F+V T+ AG DL V+V GP E + + L+ Y P PG YVV I +G + I SPF V VA K++A+GPGL G+ K A F VE+ G E G+LGF+I+GPS+AKI+C D GDGS +V YWP PGEYA+HI+CDDE+I SPYMA IQ + DP KV AYGPGL +G + PA+F V+ +AG + +K DV G + + ++ DGTY+C YTP P KHTV V++G V++P SPF+VN+ + + +KV+GPG+E+ K N T+F VDC AG GD+ + V+ ++ D+ N + TF YTI++ F+ EIP+SPF++ ++ +D K + + G+ + F + T G K ++ P + +N +TP G V V G+PI SP+ V A +N E+ + + D + +D N A + + V K++ R +V P + P EE +Y PV + E P V AYG GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP PG Y VN+L+ + HI SPF +N++ D +KV A GPGL V + + G G + + ++ V +N DGTY+ +Y P G + + + Y G V K P V V D S+I+ +GPG+EE G+ ++ FTVD L G + I P+ A DN DGT V+Y P + G++ + + ++++ +P SPF V + + +VK G GL + P+ F+V AG L + V + + + G V Y P G+ ++ + Y+ +PGSPF V + +P KV ++G G+ G + K+P FT++T AG + L + VTGP +D+ ++GDGT T Y + G YTV V Y ++ +P SPF V V + GP L G + ++PVN +NAG G LS + G I++ G +VSY+P + G Y V + + ++IP YS R + SK + + V VG V D A V C P ++ +I N DGT + Y +++G + + V + G I SPF +P S Y P GLS+ D+ F I T G ++ V PS A +DNK+GT + Y+P G + + IK HI SP I+G K + + T + P + + I+N + + PT + L + + ++ GISF P+EVGEHLV++ ++GRHIPNSP I V ++EIG+AS+VK +G GL +G E F+VDTR AGYGGLSL++EGPSKV+I+ D DGTC V+Y PTEPG YI+++K+AD +VPGSPF + G + E I R + A V+ +G +CELNL IP ++ TA V+SPSG + EI+ L N +RF+P+E G+HTVSVK HV GSPFQFTVGPL +GG KV G G+ERG A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGS GV+Y V EPGDY IKFNDEH+P SPF++ I +D+R +++ +LQ+ G + A+F I +G G I A V SPS + +++++ ++Y+V F+P ENGIH + V N S +PGSPF+V VGE T G+G+ G TG+ +EF ++TS AG GAL+VTI+GPSKV + C+E GY Y P APG Y I +KYGG NHI+GSPF ++G ET S + Q+V S T + S V +G GL A +G+++ F VD AG ++L VGV GP PCEEV+IKHLGN + V+Y+V+E+G ++L+V+WG +PGSPF I VP Sbjct: 3 VTEKDLAQDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFSQMQLENVSVALEFLER-ENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPVWE----DEGDEETKNQTPKQRLLGWIQNKIPQLPITNFSQNWQDGKALGALVDSCAPGLCPDWESWDPKKPVENAREAMQQADDWLGVPQVIAPEEIIDPNVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGLGVEPTGNMVKRSAPFTVETISAGTGEVLVYIEDPEGNREEAKVTGNNDKNKTFSVEYVPKVTGMHKVTVLFAGQHIAKSPFEVNVEKAQGDASKVTAKGPGLEPIGNIANKPTYFDIYTAGAGVGDIGIEVIDPQGRNNTVELALEDKGNCVYRCTYKPIKAGPHNVAINFGGEATPKSPYLVSI-GEACNPNA--CRANGRGLQPKGVRIRETADFRVDTKAAGSGDLHVSVKGPKGLDEVLKQSESLDGLHLFEYYPLTPGKYVVAITWGGHHIPKSPFEVQVALEAGPQKVRAWGPGLYSGMAGKAADFVVESVGSEVGSLGFAIEGPSQAKIECEDQGDGSCDVRYWPKEPGEYAIHIMCDDEDIQNSPYMALIQPASGDIDPDKVKAYGPGLEKTGCIVSTPAEFAVDPTDAGK-AALKIYSQDVEGNPVDIMTKEKPDGTYACSYTPAKPIKHTVAVTWGGVSVPNSPFRVNIGQGSHPHLVKVFGPGVEKTGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVISDEEEDIDFDIIPNANDTF-TVKYMPPAAGRYTIKVLFAGEEIPESPFRIKVDPSHDASKVRAEGPGLSKSGVENGKPSHFTVYTKGAG-KAPVDVSFTGPAPGDAVKDFEIIDNYDYSHTVRYTPVQQGKMKVAVNYGGDPIPKSPFTVGVAAPLDLNKIRINGLESRVEVGKDQQFIVDPNGAGGQGKLEV---KISSPSRKSVPCLVEPVPGNECSTVKYIPKEEGLYNVDVSYDGNPVPGSPYVVEATLPPDPSKVKAYGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTTPGEYFVNILFEETHIPGSPFQ----------ANVEMPFDPSKVIATGPGLEHGKVGEAGLIHVDCSQA-----GPGNLAVEAVSDSGSKAEVNVQDNKDGTYTVTYVPLFAGMYTLALKYGGEQVPKFPARVKVDPAVDTSKIKVFGPGIEEKGVFREATTDFTVDAKSLTKTGGNHVKTKITNPSGASTDYLLRDNGDGTYYVEYTPFEKGAHAIKVTYDDEPVPNSPFKVGVTEGCYPDRVKAQGAGLTE--ALTNKPNLFSVITRGAGIGGLGITVEGPSESKMS----CKDNKDGSCSVEYTPYVTGDYDVNITYDGEHIPGSPFRVPVKDVVDPSKVKISGPGL----GTAVRAKIPQQFTVDTSKAGIAPLAVQVTGPRGTVEPVDLVDNGDGTHTVSYTPTLEGPYTVAVQYADEEIPRSPFKVKVLPTYDASKVTASGPGL--CAQGISASLPVNFAVDAKNAGLGPLSVQITDQEGKPKKAQIQDNNDGTYSVSYIPDRTGRYHVAVKYGGDDIP--------------YSPYRIRAMSIGDASKCTVAGPGIQAAVKTGEEVGFVVDATTAGKGKVTCSILGPDGLENEADVIENVDGTYDIYYTTAKTGPYVIHVRFGGADIPNSPFTVMATDEVPVQVQQQSLSACPPGYQPLVSETDYAQVGSMNGLSFRPFDLVIPFAIRT-----GEITGDVHMPSGKTAPADIVDNKDGTVSIRYVPTETGLHELAIKCNGAHIPESPLQFFVNYPNTGSVSAYGPGLIYGVANKPATFTIITEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYNILVKYNDTHIAGSPFIAKITGISFIPREVGEHLVSIKKNGRHIPNSPISIMVYQSEIGDASKVKAFGPGLIEGRTYEMSDFIVDTREAGYGGLSLAVEGPSKVDIQTEDLEDGTCQVSYCPTEPGVYIVSIKFADEHVPGSPFTAKVMG--EGRVKESITRRRKAPSVASVGGLCELNLKIPEIDRNELTAEVVSPSGRKQEAEIVDLGQNTSCVRFVPQETGIHTVSVKYRGEHVPGSPFQFTVGPLGEGGAEKVKAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSSGVSYVVQEPGDYDVIIKFNDEHIPQSPFLVPIVATS---------------DDARRLTVTSLQESGLKVNQPASFAIRLNG-ARGKIDAKVHSPSGAVEECFVTELEPDKYAVRFMPRENGIHMIDVKFNGSHVPGSPFKVRVGEAGQEGDPGLVTAYGDGLETGTTGKQSEFIINTSKAGPGALSVTIEGPSKVTMECKECPEGYRVLYTPMAPGIYMIGVKYGGPNHIVGSPFKAKVTGQRLVGIGGTSETSSIIVQSVTRASTETTYSALPRFASDATKVTSKGAGLSKAFLGQKSTFTVDCSKAGSNILLVGVHGPTLPCEEVSIKHLGNKHYTVHYHVKERGDYMLVVKWGEEHIPGSPFHITVP 2550
BLAST of Filamin vs. Ensembl Xenopus
Match: coq2 (coenzyme Q2 4-hydroxybenzoate polyprenyltransferase [Source:Xenbase;Acc:XB-GENE-967037]) HSP 1 Score: 1419.06 bits (3672), Expect = 0.000e+0 Identity = 962/2614 (36.80%), Postives = 1352/2614 (51.72%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKT-NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP-YKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNT-TPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVP--VKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAIDNK---AYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIY---------PVQRTNEKAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQ-PQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLE---------------------------------------RNGSRV-----FTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIE--------GPILN-EVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAF-------QPQEQYSIERTTHHYTTEQSKPI------IRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPG------YNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPS--KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPF------RXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK N I DLQ DL+DGLKLI L++ LS +R H RPNFR KLENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+WE ED Q +PKQRLLGWI +K+P P+ NF DW DG A+GALVD CAPGLCP+W WDP Q ++NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L APL K + + AYGPG+E GN + PA FTV+T NAG G + + V +P+G E ++ + +K YS SY+P + G +++ + FA I SPF VNV A GD +KVTA GPG+EPVGN + T+F+++TA AG G V +I+D + +D+V+ + + +N + Y EG H V + FAG QI P+ V + S+ N +A ATGRG+QP+GVRV++VA+F+V T+ A +L + G G + E +I+ +YEC Y P PF V V+P K++A+GPGL G+V K A F VE G E G LGFSI+GPS+AKI+C D GDGS +V YWPT PGEYAVH++CDDE+I SP++A I + P KV AYG GL +G PA+F ++ + AG+ + +K D G I ++I+DN D TY C Y P P KHT+I+++G VNIP SP++V+V E + +KVYGPG+E+ K N TYF VDC AG GD+ I + E D ++ +DN T YTI + F++ EIP SPF+V ++ +D K + LN T +G+ F + T G S G V + + + +T G TV+V G+PI SP+ V ++ + + + +++ID K + + S P+ V+T + + P EE Y PV + E P V AYG GL G PA F ID+ LG+T+EGP EAKI+ DNGDG+CSV+YLP EPG Y +N+L+ + HI SPF I P + D +KVTA GPGL + FTV+ G + I + ++ + NN DGTYS +Y PA G + I I Y G V K P V V D S ++ +GPG+E G+ ++ +FTVD L G + I GP+ A + F DN DGT VQY + G + + + +++ +P SPF VP+ + D S+V+ YGPGLE ++GS FTP + V+ + G + A+ L + G V Y P G + V Y + +VP SPF VL + + KV +G G+ I +P FTI+ RDAGE L + + P + ++ +GDGT+T Y D+ G YT+ + YG +P SPF + +C + G L + +G+ I V+ + AG G ++ K P G + + + G + Y + G Y + + F E+IPN A +P + + + + T E P+ +R V+ F G + VR PS + P + +N DGT+TV++ P E GLHE+++ Y+G I GSP +FYVD+ I S V+AYGPGLS+G + A FTIVTKDAG GGLSLAVEGPSKAEI C DNK+GTC VSY+P APGDY+I ++F DKHI GSPFT+KI G+ R SQ+ VGT++DV L+I+E+D++ L A + +P+G EE C LKRL N ++GISFTPKEVGEH+V+V ++G+H+ NSPFKI VG +EIG+AS+VK+ G GL +G+ E +F+VDTRNAGYGGL LSIEGPSKV+I C D DGTC V+Y PTEPGTYIIN+K+A+ +VPGSPF V + G + E I R + A ++ IG+ C+LNL IPG Q T + S ++ E +S + +E+ V ++ V G PF G + G + GS T EAGA ++ + PS A+ + D +D + V + E G + S+K+ +HVPGSPF + P + + + G A F I G +S V PS E + + V ++ E G + V + N+ IP SPF R G F N G + + PS + C +E Y+ ++P G ++I +K+ G HI GSPF + + G Q+ D P V G GL+ G+ +EFIV AG L V + GP + + G ++V+Y G +L+ +++G + GSPF+ V Sbjct: 26 EKDLAEDAPWKKIQQNTFTRWCNEHLKCMNKRIGDLQKDLSDGLKLIGLLEVLSQKKMYRKYHSRPNFRQMKLENVSVALEFLDR-EHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDEEDAKKQ----TPKQRLLGWIQNKIPQLPITNFHRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRSKQLHPKKANAYGPGIEPHGNMVLKPAYFTVETINAGLGEVLVFVEDPEGHTEEAKVIPNNDKNRTYSVSYVPKVAGLHKVTVLFAGQNINKSPFNVNVAMALGDANKVTARGPGLEPVGNVANKPTYFDIYTAGAGSGDVGVIIVDPQNHQDTVEVILEDKGDNIYRCTYRPNMEGPHKVFITFAGSQIPKCPYVVNI-SEACNPNA--CRATGRGLQPKGVRVKEVADFKVFTKGAEVENLKSLLKGQG-TEEPVKIRDAGDGVYECDYYP-------------------VPFEVQVSPEVGLQKVRAWGPGLETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIKDSPFIAHILPASNKGFPEKVKAYGQGLEPTGCIVEHPAEFTIDARAAGT-AELKIYAQDAEGSPIDIKIKDNGDNTYVCVYVPTKPIKHTIIITWGGVNIPNSPYRVSVGEGSHPNKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTV---KYTPPGAGKYTIMVLFADQEIPTSPFRVKVDPSHDASKVRAEGPGLNRTGVEVGKPTHFTVYTKGAGKAKLDVQFAGSIKGEAVQDFEIIDNHDYSYTVKYTAVQQGTLTVSVTYGGDPIPKSPFNVNVAPPLDLSKVKVQGLNNKVDVGKDQEFSIDTSGAGGQGKVDVKITSPSRRPIP-CKVETGVTSDIHTVKYMPPEEGPYKVDISYDGHPVPGSPFSVEAVMPPDSSKVRAYGPGLKGGFVGKPAPFAIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCSVSYLPTEPGEYSINILFAESHIPGSPFKADIRP-------VFDPSKVTASGPGLEKGKA--GEVATFTVDCSKA---GDAELTIEILSDSGSKAEVLIQNNSDGTYSITYIPACPGAYTITIKYGGHAVPKFPVRVNVEPAVDTSGVKVFGPGVEPRGVLREVTTEFTVDARSLTKTGGSHVTTRILGPSGAVTESFLSDNGDGTYHVQYTAYEDGVHLIEVLYDDVPVPKSPFRVPVTEGCDPSRVRAYGPGLEGGLLNKSNRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGDYDVNITFGGRPIPGIPCSSDFHSGFAGARTLRDNGDGTHTVNYTPATDGPYTVSVRYADQEVPRSPFKIKVLPTHDASKVRASGPGLNTAG---IPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRGNGDGTYTVSYVPDMAGRYTITIKYGGDEIPYSPFRIHAVPTGDASKCLVTVSIGGHGLGTCLGPSIQIGEETVITVDAKAAGKGKVTCKVSTPDGAELDVDVVENQDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVVACDTIPIIEEPCDTVQLHQ-PYPATEEPVVPVENLDTMLRPFNLVIPFTVQKGEITGEVR----MPSGKTARPNITDNKDGTVTVKFAPVEKGLHEMDIKYDGNHIPGSPLQFYVDA-INSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYMPTAPGDYNIIVRFDDKHIPGSPFTSKITGDDSMRTSQLNVGTSTDVSLKITESDLSLLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVKKNGKHVTNSPFKIMVGPSEIGDASKVKVSGKGLLEGVTFEVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVSYCPTEPGTYIINIKFAEKHVPGSPFMVKVTG--EGRMKESITRRRQAPSIASIGSTCDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGG--ETKREVRVE------ESTQVGGDPFHNVFGEFL--GRESLGTFGS------------ITRQEGEAGAQEMTAQVTSPSGQTADAEIIDGEDNTYSVRFVPQEMGAHTVSVKYRGQHVPGSPFQFTV--GPMGE------------GGAHKVRAGGPGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFEDRKDGSCGVSYIVQEAGDYEVSIKFNDEHIPDSPFVVPVASRSDDARRLTVTSLQETGIIVNQPASFAVQLNGARGVIDAKVHTPSGMVEECYVSEVDSDKYSIRFIPRENGVHSIDVKFNG-RHIPGSPFKIRV-GEQSQAGD-------------------------PGLVTAYGLGLEGGVTGRPSEFIVSTLNAGAGSLSVTIDGPSKVKLDCQDSPEG---YKVSYTPMAPGNYLISIKYGGPQHIVGSPFKARV 2515 HSP 2 Score: 952.97 bits (2462), Expect = 0.000e+0 Identity = 748/2394 (31.24%), Postives = 1155/2394 (48.25%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES----KIKAFGPGL--TGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCV--DNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPS-TVKAECF-DVTGQT---IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGI----SVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQE--TNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEYPETETPLLIS--ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQ---------RTNEKAELRK----PNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYI--DNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPG--------------------------------------------------SPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVT----GEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPF------IVPVHSE-AKPEQCYIEGPILNE--VPVGK--------TVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQY----------AFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPV-GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPF--KFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNK--NGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKI----FGEPKKRSQICVGTTSDVPLRISETDINNLNA-------IVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFV-GENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADS-NVPGSPFAVNIG---GYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXX---------XXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRET-----KSLTQTVHMISGSTQKGP---SKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 ++ +V A GPGLE GN P F + T AG G++ +I+++P+ ++ E+ + Y C+Y P MEG +++ I FA S+IP P+ VN+ A +P+ A+G G++P G V F VFT A ++ +L +G ++ VK + +G++ + + ++Q SP ++ A G G+ E V A+F V LG ++ GP ++ +C K C + Y P PG Y V + + I SPF + P K+KA+G GL TG IV PA F ++ T L + + ID DNGD + Y PT P ++ + I NIP SPY + + P KV YGPG+ +G+ N+P F V+ AG ++ +C V G I I N++ T++ +YTP GK+T++V + + IP SPF+V V + +A+ ++ GPG+ R + T+F V K AG + + S+ E ++D ++ DN D ++T+KYT G + + IP+SPF V + D K K+ LNN +G+ EF I T G + + ++ + SP+ +P K++ T++ + P GP+ V + G+P+ SP+ V A D + Y + A +AID K + + P E + ++ N + S ++ P E Y + + KA++R VTA G GL KG A A+F +D ++ A L + I +K + + +N DGT S+ Y+P PG+Y + + Y + P V + P D + V +GPG+ P GV ++ ++FTV+A+ + G V I P + + +N DGTY Y+ DG H I++ YD VPV KSP+ VPV +G DPSR+RAYGPGLE G+ + +FTV+ GAG GGLGL+IEGP++A++ C DNKDG+CSV+Y+P PG YDV+I F + IPG SPF + + D SKV+ GPGL G P +FT+DA AGE L V ++D K K A I G + V+Y+P+ G I + Y ++P SPF + + + + K +VT G G+ G I ++ T++ + AG+ + V+ P+ +++DV + DGTF Y PG Y + + +G +++P SPF +P+ E Q + P E VPV + IP Q G ++ + P G +I + + G TV + P + G +E+ + ++ +IP ++ Y A+ P + + +T I+ + V GP +A + C N+ DGT TV Y P+ G + + V ++ + I GSPF K D ++ + Q+ G S I D L+ ++ PS E C+ + N +S+ P G++ + +K KH+ SPF + G+ K G V ++E ++ NA + P+ + +C + +++G +S+ P E G +++N+ + +H+P SPF + V GE + + + + + TC + + +S E ++ + T T G V+ +S V G PF G G S I R + A ++ TA V SPSG EII DN +S+RF+P+E+G HTVSVK +HV GSPFQFTVGP+ +GG HKV G G+ERG+A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGSCGV+Y V E GDY SIKFNDEH+P SPF++ P +S S +D+R +++ +LQ+ G + A+F + +G G I A V +PS + +S++D+++YS+ F+P ENG+H++ V N IPGSPF++ VGE + + G G+ G TGR +EF V T NAG G+L+VTIDGPSKV+L+CQ++ GY +Y P APG+Y ISIKYGG HI+GSPF ++G S+ ET +++T++ + G P S V G GL A +G++N F VD AG ++L VGV GP PCEEV +KH+GN + V Y V++KG ++L+V+WG+ +VPGSPF++ VP Sbjct: 375 DANKVTARGPGLEPVGNVANKPTYFDIYTAGAGSGDVGVIIVDPQNHQDTVEVILEDKGDNIYRCTYRPNMEGPHKVFITFAGSQIPKCPYVVNISEAC-NPNACRATGRGLQPKGVRVKEVADFKVFTKGAEVENLKS-LLKGQGTEEPVKIR--------------DAGDGVYECDYYPVPFEVQVSP----------EVGLQKVRAWGPGL--ETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSC--DVRYWPTEPGEYAVHVICDDEDIKDSPFIAHILPASNKGFPEKVKAYGQGLEPTGCIVEHPAEFTIDARAAGTAELKIYAQDAEGSPIDIKIKDNGDNTYVCVYVPTKPIKHTIIITWGGVNIPNSPYRVSVGEGSH---PNKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGKYTIMVLFADQEIPTSPFRVKVDPSHDASKVRAEGPGLNRTGVEVGKPTHFTVYTKGAGKAKLDVQFAGSIKGEAVQDFEII--DNHDYSYTVKYTAVQQGTLTV-SVTYGGDPIPKSPFNVNVAPPLDLSKVKVQGLNNKVDVGKDQEFSIDTSGAGGQGKVDVKITSPSRRPIPCKVETGVTSDIHTVKYMPPEEGPYKVDISYDGHPVPGSPFSVEAVMPPDSSKVRAYGPGLKGGFVGKPAPFAIDTKGAGTGGLGLTVEG--PCE-AKIECQDNGDGSCSVSYLPTEPGEYSINILFAESHIPGSPFKADIRPVFDPSKVTASGPGLEKGKAGEVATFTVDCSKAGDAELTIEILSDSGSKAEVLIQNNSDGTYSITYIPACPGAYTITIKYGGHAVPKFPVRVNVEPAV-------DTSGVKVFGPGVEPRGVLREVTTEFTVDARSLTKTGGSHVTTRILGPSGAVTESFLSDNGDGTYHVQYTAYEDGVHLIEVLYDDVPVPKSPFRVPVTEGCDPSRVRAYGPGLEGGLLNKSNRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGDYDVNITFGGRPIPGIPCSSDFHSGFAGARTLRDNGDGTHTVNYTPATDGPYTVSVRYADQEVPRSPFKIKVLPTHDASKVRASGPGLNTAGIPASLPVEFTIDARDAGEGLLTVQILDPEGKP-KKANIRGNGD-GTYTVSYVPDMAGRYTITIKYGGDEIPYSPFRIHAVPTGDASKCLVTVSIGGHGLGTCLGPSIQIGEETVITVDAKAAGKGKVTCKVSTPDGAELDVDVVENQDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVVACDTIPIIEEPCDTVQLHQPYPATEEPVVPVENLDTMLRPFNLVIPFTVQK---GEITGEVRMPSGKTARPNITDNKDGTVTVKFAPVEKGLHEMDIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFT------IVTKDAGEGGLSLAVEGPS----KAEITCKDNK----------DGTCTVSYMPTAPGDYNIIVRFDDKHIPGSPFTSKITGDDSMRTSQLNV---GTS-----TDVSLKITESDLSL--LTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVKKNGKHVTNSPFKIMVGPSEIGDASKVKVSGKGLLEGVTFEVAEFIVDTRNAGYGGLGLSIEGPSKVDINC--EDMEDGTCKVSYCPTEPGTYIINIKFAEKHVPGSPFMVKVTGEGRMKESITRRRQAPSI--ASIGSTCDLNLKIPGNWFQMVSAQ-ERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFHNVFGEFLGRESLGTFGSITRQEGEAGAQEM------------------TAQVTSPSGQTADAEIIDGEDNTYSVRFVPQEMGAHTVSVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVQEAGDYEVSIKFNDEHIPDSPFVV-----PVASRS----------DDARRLTVTSLQETGIIVNQPASFAVQLNG-ARGVIDAKVHTPSGMVEECYVSEVDSDKYSIRFIPRENGVHSIDVKFNGRHIPGSPFKIRVGEQSQAGDPGLVTAYGLGLEGGVTGRPSEFIVSTLNAGAGSLSVTIDGPSKVKLDCQDSPEGYKVSYTPMAPGNYLISIKYGGPQHIVGSPFKARVTGVRLSGGHSLHETSTVLVETVTKSSASVGGYAMTAPKFSSDASKVVSRGPGLSKAFVGQKNTFTVDCSKAGTNMLMVGVHGPKTPCEEVYVKHMGNRLYNVTYTVKDKGDYILIVKWGDQNVPGSPFQVAVP 2648
BLAST of Filamin vs. Ensembl Xenopus
Match: coq2 (coenzyme Q2 4-hydroxybenzoate polyprenyltransferase [Source:Xenbase;Acc:XB-GENE-967037]) HSP 1 Score: 1418.29 bits (3670), Expect = 0.000e+0 Identity = 907/2311 (39.25%), Postives = 1298/2311 (56.17%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVIL-DTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES----KIKAFGPGL--TGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCV--DNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPS-TVKAECF-DVTGQT---IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGI----SVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQE--TNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEYPETETPLLIS--ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQ---------RTNEKAELRK----PNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYI--DNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIE--------GPILN-EVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTH--HYTTEQSKPI------IRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXX---------XXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRET-----KSLTQTVHMISGSTQKGP---SKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 ++ +V A GPGLE GN P F + T AG G++ +I+++P+ ++ E+ + Y C+Y P MEG +++ I FA S+IP P+ VN+ A +P+ A+G G++P G V F VFT A ++ ++ KG ++ VK I + + +Y G ++V + + G I SPF V VS + ++ A G G+ E V A+F V LG ++ GP ++ +C K C + Y P PG Y V + + I SPF + P K+KA+G GL TG IV PA F ++ T L + + ID DNGD + Y PT P ++ + I NIP SPY + + P KV YGPG+ +G+ N+P F V+ AG ++ +C V G I I N++ T++ +YTP GK+T++V + + IP SPF+V V + +A+ ++ GPG+ R + T+F V K AG + + S+ E ++D ++ DN D ++T+KYT G + + IP+SPF V + D K K+ LNN +G+ EF I T G + + ++ + SP+ +P K++ T++ + P GP+ V + G+P+ SP+ V A D + Y + A +AID K + + P E + ++ N + S ++ P E Y + + KA++R VTA G GL KG A A+F +D ++ A L + I +K + + +N DGT S+ Y+P PG+Y + + Y + P V + P D + V +GPG+ P GV ++ ++FTV+A+ + G V I P + + +N DGTY Y+ DG H I++ YD VPV KSP+ VPV +G DPSR+RAYGPGLE G+ + +FTV+ GAG GGLGL+IEGP++A++ C DNKDG+CSV+Y+P PG YDV+I F + IPGSPF VP+ +IVD SKVKC GPGL +G R P FTVD SKAG APL+V ++ + +P I G V Y P G + V Y + +VP SPF VL + + KV +G G+ I +P FTI+ RDAGE L + + P + ++ +GDGT+T Y D+ G YT+ + YG +P SPF + +C + G L + +G+ I V+ + AG G ++ K P G + + + G + Y + G Y + + F E+IPN S QE I + H T E P+ +R V+ F G + VR PS + P + +N DGT+TV++ P E GLHE+++ Y+G I GSP +FYVD+ I S V+AYGPGLS+G + A FTIVTKDAG GGLSLAVEGPSKAEI C DNK+GTC VSY+P APGDY+I ++F DKHI GSPFT+KI G+ R SQ+ VGT++DV L+I+E+D++ L A + +P+G EE C LKRL N ++GISFTPKEVGEH+V+V ++G+H+ NSPFKI VG +EIG+AS+VK+ G GL +G+ E +F+VDTRNAGYGGL LSIEGPSKV+I C D DGTC V+Y PTEPGTYIIN+K+A+ +VPGSPF V + G + E I R + A ++ IG+ C+LNL IP + TA V SPSG EII DN +S+RF+P+E+G HTVSVK +HV GSPFQFTVGP+ +GG HKV G G+ERG+A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGSCGV+Y V E GDY SIKFNDEH+P SPF++ P +S S +D+R +++ +LQ+ G + A+F + +G G I A V +PS + +S++D+++YS+ F+P ENG+H++ V N IPGSPF++ VGE + + G G+ G TGR +EF V T NAG G+L+VTIDGPSKV+L+CQ++ GY +Y P APG+Y ISIKYGG HI+GSPF ++G S+ ET +++T++ + G P S V G GL A +G++N F VD AG ++L VGV GP PCEEV +KH+GN + V Y V++KG ++L+V+WG+ +VPGSPF++ VP Sbjct: 354 DANKVTARGPGLEPVGNVANKPTYFDIYTAGAGSGDVGVIIVDPQNHQDTVEVILEDKGDNIYRCTYRPNMEGPHKVFITFAGSQIPKCPYVVNISEAC-NPNACRATGRGLQPKGVRVKEVADFKVFTKGAEVENLKSLLKGQVKGTEEPVK--IRDAGDGVYECDYYPVLPGKYTVTITWGGYAIPRSPFEVQVSPEVG---LQKVRAWGPGL--ETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSC--DVRYWPTEPGEYAVHVICDDEDIKDSPFIAHILPASNKGFPEKVKAYGQGLEPTGCIVEHPAEFTIDARAAGTAELKIYAQDAEGSPIDIKIKDNGDNTYVCVYVPTKPIKHTIIITWGGVNIPNSPYRVSVGEGSH---PNKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGKYTIMVLFADQEIPTSPFRVKVDPSHDASKVRAEGPGLNRTGVEVGKPTHFTVYTKGAGKAKLDVQFAGSIKGEAVQDFEII--DNHDYSYTVKYTAVQQGTLTV-SVTYGGDPIPKSPFNVNVAPPLDLSKVKVQGLNNKVDVGKDQEFSIDTSGAGGQGKVDVKITSPSRRPIPCKVETGVTSDIHTVKYMPPEEGPYKVDISYDGHPVPGSPFSVEAVMPPDSSKVRAYGPGLKGGFVGKPAPFAIDTKGAGTGGLGLTVEG--PCE-AKIECQDNGDGSCSVSYLPTEPGEYSINILFAESHIPGSPFKADIRPVFDPSKVTASGPGLEKGKAGEVATFTVDCSKAGDAELTIEILSDSGSKAEVLIQNNSDGTYSITYIPACPGAYTITIKYGGHAVPKFPVRVNVEPAV-------DTSGVKVFGPGVEPRGVLREVTTEFTVDARSLTKTGGSHVTTRILGPSGAVTESFLSDNGDGTYHVQYTAYEDGVHLIEVLYDDVPVPKSPFRVPVTEGCDPSRVRAYGPGLEGGLLNKSNRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKEIVDPSKVKCSGPGL-GSGVRAHVPQTFTVDCSKAGLAPLEV-LVQGPSGLAEPVDIRDNGD-GTHTVNYTPATDGPYTVSVRYADQEVPRSPFKIKVLPTHDASKVRASGPGLNTAG---IPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRGNGDGTYTVSYVPDMAGRYTITIKYGGDEIPYSPFRIHAVPTGDASKCLVTVSIGGHGLGTCLGPSIQIGEETVITVDAKAAGKGKVTCKVSTPDGAELDVDVVENQDGTFDIYYTAPEPGKYVITIRFGGEHIPN-SPFHVVVSKQEVMKIFLSFHPIQATEEPVVPVENLDTMLRPFNLVIPFTVQKGEITGEVR----MPSGKTARPNITDNKDGTVTVKFAPVEKGLHEMDIKYDGNHIPGSPLQFYVDA-INSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYMPTAPGDYNIIVRFDDKHIPGSPFTSKITGDDSMRTSQLNVGTSTDVSLKITESDLSLLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVKKNGKHVTNSPFKIMVGPSEIGDASKVKVSGKGLLEGVTFEVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVSYCPTEPGTYIINIKFAEKHVPGSPFMVKVTG--EGRMKESITRRRQAPSIASIGSTCDLNLKIPEAGAQEMTAQVTSPSGQTADAEIIDGEDNTYSVRFVPQEMGAHTVSVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVQEAGDYEVSIKFNDEHIPDSPFVV-----PVASRS----------DDARRLTVTSLQETGIIVNQPASFAVQLNG-ARGVIDAKVHTPSGMVEECYVSEVDSDKYSIRFIPRENGVHSIDVKFNGRHIPGSPFKIRVGEQSQAGDPGLVTAYGLGLEGGVTGRPSEFIVSTLNAGAGSLSVTIDGPSKVKLDCQDSPEGYKVSYTPMAPGNYLISIKYGGPQHIVGSPFKARVTGVRLSGGHSLHETSTVLVETVTKSSASVGGYAMTAPKFSSDASKVVSRGPGLSKAFVGQKNTFTVDCSKAGTNMLMVGVHGPKTPCEEVYVKHMGNRLYNVTYTVKDKGDYILIVKWGDQNVPGSPFQVAVP 2608 HSP 2 Score: 1112.06 bits (2875), Expect = 0.000e+0 Identity = 853/2588 (32.96%), Postives = 1249/2588 (48.26%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKT-NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEK-CQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP-YKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNT-TPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVP--VKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAIDNK---AYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIY---------PVQRTNEKAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQ-PQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPF---IVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTT----HHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRL----INNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRP--------DMHAHFTIVTK-DAGAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF--------TAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGY--NQRNT-----TASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTR--EAGAGSLSIAIEGPS--KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPF------RXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK N I DLQ DL+DGLKLI L++ LS +R H RPNFR KLENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+WE ED Q +PKQRLLGWI +K+P P+ NF DW DG A+GALVD CAPGLCP+W WDP Q ++NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L APL K + + AYGPG+E GN + PA FTV+T NAG G + + V +P+G E ++ + +K YS SY+P + G +++ + FA I SPF VNV A GD +KVTA GPG+EPVGN + T+F+++TA AG G V +I+D + +D+V+ + + +N + Y EG H V + FAG QI P+ V + S+ N +A ATGRG+QP+GVRV++VA+F+V T+ A +L + G + E+ +I+ +YEC Y P PG Y V I +G I SPF V V+P K++A+GPGL G+V K A F VE G E G LGFSI+GPS+AKI+C D GDGS +V YWPT PGEYAVH++CDDE+I SP++A I + P KV AYG GL +G PA+F ++ + AG+ + +K D G I ++I+DN D TY C Y P P KHT+I+++G VNIP SP++V+V E + +KVYGPG+E+ K N TYF VDC AG GD+ I + E D ++ +DN T YTI + F++ EIP SPF+V ++ +D K + LN T +G+ F + T G S G V + + + +T G TV+V G+PI SP+ V ++ + + + +++ID K + + S P+ V+T + + P EE Y PV + E P V AYG GL G PA F ID+ LG+T+EGP EAKI+ DNGDG+CSV+YLP EPG Y +N+L+ + HI SPF I P + D +KVTA GPGL + FTV+ G + I + ++ + NN DGTYS +Y PA G + I I Y G V K P V V D S ++ +GPG+E G+ ++ +FTVD L G + I GP+ A + F DN DGT VQY + G + + + +++ +P SPF VP+ + D S+V+ YGPGLE G + ++FTV+ AG L + + + + + G V YIP G+ ++ + + +PGSPF V +P KV +G G+ G + VP FT++ AG + LE++V GP+ + +D+ ++GDGT T Y G YTV V Y ++ VP SPF ++P H +K GP LN +P V ++ ++AG+G+L+ + + P G +I G TVSYVP G Y + + + + IP R +A + T H T I E +V+ + V C + D L + N DGT + Y E G + + + + G+ I SPF V ++ P + P M F +V G ++ V PS A DNK+GT V + P+ G + + IK+ HI GSP + + S V + + + L+ V P+ E +C K ++G +S+ P G++ + V +HIP SPF + ++ S+ LN G + + ++ L+ SI PS E C + H G +++ P E G ++++VK +V SPF + +G PS + +VS G + + + + + RN S+ PS CE + D + + P E G + +++K +HV GSPF V G K I +A+ + + + EAGA ++ + PS A+ + D +D + V + E G + S+K+ +HVPGSPF + P + + + G A F I G +S V PS E + + V ++ E G + V + N+ IP SPF R G F N G + + PS + C +E Y+ ++P G ++I +K+ G HI GSPF + + G Q+ D P V G GL+ G+ +EFIV AG L V + GP + + G ++V+Y G +L+ +++G + GSPF+ V Sbjct: 5 EKDLAEDAPWKKIQQNTFTRWCNEHLKCMNKRIGDLQKDLSDGLKLIGLLEVLSQKKMYRKYHSRPNFRQMKLENVSVALEFLDR-EHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDEEDAKKQ----TPKQRLLGWIQNKIPQLPITNFHRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRSKQLHPKKANAYGPGIEPHGNMVLKPAYFTVETINAGLGEVLVFVEDPEGHTEEAKVIPNNDKNRTYSVSYVPKVAGLHKVTVLFAGQNINKSPFNVNVAMALGDANKVTARGPGLEPVGNVANKPTYFDIYTAGAGSGDVGVIIVDPQNHQDTVEVILEDKGDNIYRCTYRPNMEGPHKVFITFAGSQIPKCPYVVNI-SEACNPNA--CRATGRGLQPKGVRVKEVADFKVFTKGAEVENLKSLLKGQVKGTEEPVKIRDAGDGVYECDYYPVLPGKYTVTITWGGYAIPRSPFEVQVSPEVGLQKVRAWGPGLETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIKDSPFIAHILPASNKGFPEKVKAYGQGLEPTGCIVEHPAEFTIDARAAGT-AELKIYAQDAEGSPIDIKIKDNGDNTYVCVYVPTKPIKHTIIITWGGVNIPNSPYRVSVGEGSHPNKVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTV---KYTPPGAGKYTIMVLFADQEIPTSPFRVKVDPSHDASKVRAEGPGLNRTGVEVGKPTHFTVYTKGAGKAKLDVQFAGSIKGEAVQDFEIIDNHDYSYTVKYTAVQQGTLTVSVTYGGDPIPKSPFNVNVAPPLDLSKVKVQGLNNKVDVGKDQEFSIDTSGAGGQGKVDVKITSPSRRPIP-CKVETGVTSDIHTVKYMPPEEGPYKVDISYDGHPVPGSPFSVEAVMPPDSSKVRAYGPGLKGGFVGKPAPFAIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCSVSYLPTEPGEYSINILFAESHIPGSPFKADIRP-------VFDPSKVTASGPGLEKGKA--GEVATFTVDCSKA---GDAELTIEILSDSGSKAEVLIQNNSDGTYSITYIPACPGAYTITIKYGGHAVPKFPVRVNVEPAVDTSGVKVFGPGVEPRGVLREVTTEFTVDARSLTKTGGSHVTTRILGPSGAVTESFLSDNGDGTYHVQYTAYEDGVHLIEVLYDDVPVPKSPFRVPVTEGCDPSRVRAYGPGLE--GGLLNKSNRFTVETRGAGTGGLGLAIEGPSEAKMS----CKDNKDGSCSVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKEIVDPSKVKCSGPGL----GSGVRAHVPQTFTVDCSKAGLAPLEVLVQGPSGLAEPVDIRDNGDGTHTVNYTPATDGPYTVSVRYADQEVPRSPFKIKVLPTHDASK---VRASGPGLNTAGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRGNGDGTYTVSYVPDMAGRYTITIKYGGDEIPYSPFRIHAVPTGDASKCLVTVSIGGHGLGTCLGPSIQIGEETVITVDAKAAG-----KGKVTCKVSTPDGAELDVDVVENQDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVVVSKQEVMKIFLSFHPIQATEEPVVPVENLDTMLRPFNLVIPFTVQKGEITGEVRMPSGKTARPNITDNKDGTVTVKFAPVEKGLHEMDIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITC--KDNKDGTCTVSYMPTAPGDYNIIVRFDDKHIPGSPFTSKITGDDSMRTSQ-------LNVGTSTDVSLKITESD---LSLLTASIRAPSGNEEPCLLKRLPNRHIG---ISFTPKEVGEHVVSVKKNGKHVTNSPFKIMVG--PSE------IGDASKVKVSGKGLLEGVTFEVAEFIVDTRNAGYGGLGLSIEGPSKVDINCE--DMEDGTCKVSYCPTEPGTYIINIKFAEKHVPGSPFMVKV---TGEGRMKESITRRRQAPSIASIGSTCDLNLKIPEAGAQEMTAQVTSPSGQTADAEIIDGEDNTYSVRFVPQEMGAHTVSVKYRGQHVPGSPFQFTV--GPMGE------------GGAHKVRAGGPGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFEDRKDGSCGVSYIVQEAGDYEVSIKFNDEHIPDSPFVVPVASRSDDARRLTVTSLQETGIIVNQPASFAVQLNGARGVIDAKVHTPSGMVEECYVSEVDSDKYSIRFIPRENGVHSIDVKFNG-RHIPGSPFKIRV-GEQSQAGD-------------------------PGLVTAYGLGLEGGVTGRPSEFIVSTLNAGAGSLSVTIDGPSKVKLDCQDSPEG---YKVSYTPMAPGNYLISIKYGGPQHIVGSPFKARV 2475
BLAST of Filamin vs. Ensembl Xenopus
Match: coq2 (coenzyme Q2 4-hydroxybenzoate polyprenyltransferase [Source:Xenbase;Acc:XB-GENE-967037]) HSP 1 Score: 1405.96 bits (3638), Expect = 0.000e+0 Identity = 897/2295 (39.08%), Postives = 1281/2295 (55.82%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVIL-DTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES----KIKAFGPGL--TGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCV--DNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFD-PLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGI----SVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQE--TNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEYPETETPLLIS--ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQ---------RTNEKAELRK----PNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYI--DNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPI------IRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXX---------XXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRET-----KSLTQTVHMISGSTQKGP---SKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 ++ +V A GPGLE GN P F + T AG G++ +I+++P+ ++ E+ + Y C+Y P MEG +++ I FA S+IP P+ VN+ A +P+ A+G G++P G V F VFT A ++ ++ KG ++ VK I + + +Y G ++V + + G I SPF V VS + ++ A G G+ E V A+F V LG ++ GP ++ +C K C + Y P PG Y V + + I SPF + P K+KA+G GL TG IV PA F ++ T L + + ID DNGD + Y PT P ++ + I NIP SPY L F PL G+ PA+ ++ FD+ I+++ND T++ +YTP GK+T++V + + IP SPF+V V + +A+ ++ GPG+ R + T+F V K AG + + S+ E ++D ++ DN D ++T+KYT G + + IP+SPF V + D K K+ LNN +G+ EF I T G + + ++ + SP+ +P K++ T++ + P GP+ V + G+P+ SP+ V A D + Y + A +AID K + P E + ++ N + S ++ P E Y + + KA++R VTA G GL KG A A+F +D ++ A L + I +K + + +N DGT S+ Y+P PG+Y + + Y + P V + P D + V +GPG+ P GV ++ ++FTV+A+ + G V I P + + +N DGTY Y+ DG H I++ YD VPV KSP+ VPV +G DPSR+RAYGPGLE G+ + +FTV+ GAG GGLGL+IEGP++A++ C DNKDG+CSV+Y+P PG YDV+I F + IPGSPF VP+ +IVD SKVKC GPGL +G R P FTVD SKAG APL+V ++ + +P I G V Y P G + V Y + +VP SPF VL + + KV +G G+ I +P FTI+ RDAGE L + + P + ++ +GDGT+T Y D+ G YT+ + YG +P SPF + +C + G E +G+ I V+ + AG G ++ K P G + + + G + Y + G Y + + F E+IPN S QE T E P+ +R V+ F G + VR PS + P + +N DGT+TV++ P E GLHE+++ Y+G I GSP +FYVD+ I S V+AYGPGLS+G + A FTIVTKDAG GGLSLAVEGPSKAEI C DNK+GTC VSY+P APGDY+I ++F DKHI GSPFT+KI G+ R SQ+ VGT++DV L+I+E+D++ L A + +P+G EE C LKRL N ++GISFTPKEVGEH+V+V ++G+H+ NSPFKI VG +EIG+AS+VK+ G GL +G+ E +F+VDTRNAGYGGL LSIEGPSKV+I C D DGTC V+Y PTEPGTYIIN+K+A+ +VPGSPF V + G + E I R + A ++ IG+ C+LNL IP + TA V SPSG EII DN +S+RF+P+E+G HTVSVK +HV GSPFQFTVGP+ +GG HKV G G+ERG+A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGSCGV+Y V E GDY SIKFNDEH+P SPF++ P +S S +D+R +++ +LQ+ G + A+F + +G G I A V +PS + +S++D+++YS+ F+P ENG+H++ V N IPGSPF++ VGE + + G G+ G TGR +EF V T NAG G+L+VTIDGPSKV+L+CQ++ GY +Y P APG+Y ISIKYGG HI+GSPF ++G S+ ET +++T++ + G P S V G GL A +G++N F VD AG ++L VGV GP PCEEV +KH+GN + V Y V++KG ++L+V+WG+ +VPGSPF++ VP Sbjct: 354 DANKVTARGPGLEPVGNVANKPTYFDIYTAGAGSGDVGVIIVDPQNHQDTVEVILEDKGDNIYRCTYRPNMEGPHKVFITFAGSQIPKCPYVVNISEAC-NPNACRATGRGLQPKGVRVKEVADFKVFTKGAEVENLKSLLKGQVKGTEEPVK--IRDAGDGVYECDYYPVLPGKYTVTITWGGYAIPRSPFEVQVSPEVG---LQKVRAWGPGL--ETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSC--DVRYWPTEPGEYAVHVICDDEDIKDSPFIAHILPASNKGFPEKVKAYGQGLEPTGCIVEHPAEFTIDARAAGTAELKIYAQDAEGSPIDIKIKDNGDNTYVCVYVPTKPIKHTIIITWGGVNIPNSPYRVSYSLIGLCFSSPLFFRDVSIGIKCAPGVVGPAEADID--------------FDI--------IKNDND-TFTVKYTPPGAGKYTIMVLFADQEIPTSPFRVKVDPSHDASKVRAEGPGLNRTGVEVGKPTHFTVYTKGAGKAKLDVQFAGSIKGEAVQDFEII--DNHDYSYTVKYTAVQQGTLTV-SVTYGGDPIPKSPFNVNVAPPLDLSKVKVQGLNNKVDVGKDQEFSIDTSGAGGQGKVDVKITSPSRRPIPCKVETGVTSDIHTVKYMPPEEGPYKVDISYDGHPVPGSPFSVEAVMPPDSSKVRAYGPGLKGGFVGKPAPFAIDTKGAGTGG--LGLTVEGPCE-AKIECQDNGDGSCSVSYLPTEPGEYSINILFAESHIPGSPFKADIRPVFDPSKVTASGPGLEKGKAGEVATFTVDCSKAGDAELTIEILSDSGSKAEVLIQNNSDGTYSITYIPACPGAYTITIKYGGHAVPKFPVRVNVEPAV-------DTSGVKVFGPGVEPRGVLREVTTEFTVDARSLTKTGGSHVTTRILGPSGAVTESFLSDNGDGTYHVQYTAYEDGVHLIEVLYDDVPVPKSPFRVPVTEGCDPSRVRAYGPGLEGGLLNKSNRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKEIVDPSKVKCSGPGL-GSGVRAHVPQTFTVDCSKAGLAPLEV-LVQGPSGLAEPVDIRDNGD-GTHTVNYTPATDGPYTVSVRYADQEVPRSPFKIKVLPTHDASKVRASGPGLNTAG---IPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRGNGDGTYTVSYVPDMAGRYTITIKYGGDEIPYSPFRIHAVPTGDASKCLVTG----EPAIGEETVITVDAKAAGKGKVTCKVSTPDGAELDVDVVENQDGTFDIYYTAPEPGKYVITIRFGGEHIPN-SPFHVVVSKQEVMKSASKAPAATEEPVVPVENLDTMLRPFNLVIPFTVQKGEITGEVR----MPSGKTARPNITDNKDGTVTVKFAPVEKGLHEMDIKYDGNHIPGSPLQFYVDA-INSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYMPTAPGDYNIIVRFDDKHIPGSPFTSKITGDDSMRTSQLNVGTSTDVSLKITESDLSLLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVKKNGKHVTNSPFKIMVGPSEIGDASKVKVSGKGLLEGVTFEVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVSYCPTEPGTYIINIKFAEKHVPGSPFMVKVTG--EGRMKESITRRRQAPSIASIGSTCDLNLKIPEAGAQEMTAQVTSPSGQTADAEIIDGEDNTYSVRFVPQEMGAHTVSVKYRGQHVPGSPFQFTVGPMGEGGAHKVRAGGPGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFEDRKDGSCGVSYIVQEAGDYEVSIKFNDEHIPDSPFVV-----PVASRS----------DDARRLTVTSLQETGIIVNQPASFAVQLNG-ARGVIDAKVHTPSGMVEECYVSEVDSDKYSIRFIPRENGVHSIDVKFNGRHIPGSPFKIRVGEQSQAGDPGLVTAYGLGLEGGVTGRPSEFIVSTLNAGAGSLSVTIDGPSKVKLDCQDSPEGYKVSYTPMAPGNYLISIKYGGPQHIVGSPFKARVTGVRLSGGHSLHETSTVLVETVTKSSASVGGYAMTAPKFSSDASKVVSRGPGLSKAFVGQKNTFTVDCSKAGTNMLMVGVHGPKTPCEEVYVKHMGNRLYNVTYTVKDKGDYILIVKWGDQNVPGSPFQVAVP 2568 HSP 2 Score: 1066.99 bits (2758), Expect = 0.000e+0 Identity = 834/2574 (32.40%), Postives = 1229/2574 (47.75%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKT-NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEK-CQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP-YKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNT-TPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVP--VKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAIDNK---AYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIY---------PVQRTNEKAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQ-PQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPF---IVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRL----INNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVD--------STIPSGQVTAYGPGLSYGRPDMHAHFTIVTK-DAGAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR--------SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGY--NQRNT-----TASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTR--EAGAGSLSIAIEGPS--KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPF------RXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK N I DLQ DL+DGLKLI L++ LS +R H RPNFR KLENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+WE ED Q +PKQRLLGWI +K+P P+ NF DW DG A+GALVD CAPGLCP+W WDP Q ++NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L APL K + + AYGPG+E GN + PA FTV+T NAG G + + V +P+G E ++ + +K YS SY+P + G +++ + FA I SPF VNV A GD +KVTA GPG+EPVGN + T+F+++TA AG G V +I+D + +D+V+ + + +N + Y EG H V + FAG QI P+ V + S+ N +A ATGRG+QP+GVRV++VA+F+V T+ A +L + G + E+ +I+ +YEC Y P PG Y V I +G I SPF V V+P K++A+GPGL G+V K A F VE G E G LGFSI+GPS+AKI+C D GDGS +V YWPT PGEYAVH++CDDE+I SP++A I + P KV AYG GL +G PA+F ++ + AG+ + +K D G I ++I+DN D TY C Y P P KHT+I+++G VNIP SP++V+ G + F D + G+ E D ++ +DN T YTI + F++ EIP SPF+V ++ +D K + LN T +G+ F + T G S G V + + + +T G TV+V G+PI SP+ V ++ + + + +++ID K + + S P+ V+T + + P EE Y PV + E P V AYG GL G PA F ID+ LG+T+EGP EAKI+ DNGDG+CSV+YLP EPG Y +N+L+ + HI SPF I P + D +KVTA GPGL + FTV+ G + I + ++ + NN DGTYS +Y PA G + I I Y G V K P V V D S ++ +GPG+E G+ ++ +FTVD L G + I GP+ A + F DN DGT VQY + G + + + +++ +P SPF VP+ + D S+V+ YGPGLE G + ++FTV+ AG L + + + + + G V YIP G+ ++ + + +PGSPF V +P KV +G G+ G + VP FT++ AG + LE++V GP+ + +D+ ++GDGT T Y G YTV V Y ++ VP SPF ++P H +K GP LN +P V ++ ++AG+G+L+ + + P G +I G TVSYVP G Y + + + + IP R +A T + SK ++ E ++ + + V C + D L + N DGT + Y E G + + + + G+ I SPF V S P+ P + M F +V G ++ V PS A DNK+GT V + P+ G + + IK+ HI GSP + + S V + + + L+ V P+ E +C K ++G +S+ P G++ + V +HIP SPF + ++ S+ LN G + + ++ L+ SI PS E C + H G +++ P E G ++++VK +V SPF + +G PS + +VS G + + + + + RN S+ PS CE + D + + P E G + +++K +HV GSPF V G K I +A+ + + + EAGA ++ + PS A+ + D +D + V + E G + S+K+ +HVPGSPF + P + + + G A F I G +S V PS E + + V ++ E G + V + N+ IP SPF R G F N G + + PS + C +E Y+ ++P G ++I +K+ G HI GSPF + + G Q+ D P V G GL+ G+ +EFIV AG L V + GP + + G ++V+Y G +L+ +++G + GSPF+ V Sbjct: 5 EKDLAEDAPWKKIQQNTFTRWCNEHLKCMNKRIGDLQKDLSDGLKLIGLLEVLSQKKMYRKYHSRPNFRQMKLENVSVALEFLDR-EHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDEEDAKKQ----TPKQRLLGWIQNKIPQLPITNFHRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRSKQLHPKKANAYGPGIEPHGNMVLKPAYFTVETINAGLGEVLVFVEDPEGHTEEAKVIPNNDKNRTYSVSYVPKVAGLHKVTVLFAGQNINKSPFNVNVAMALGDANKVTARGPGLEPVGNVANKPTYFDIYTAGAGSGDVGVIIVDPQNHQDTVEVILEDKGDNIYRCTYRPNMEGPHKVFITFAGSQIPKCPYVVNI-SEACNPNA--CRATGRGLQPKGVRVKEVADFKVFTKGAEVENLKSLLKGQVKGTEEPVKIRDAGDGVYECDYYPVLPGKYTVTITWGGYAIPRSPFEVQVSPEVGLQKVRAWGPGLETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIKDSPFIAHILPASNKGFPEKVKAYGQGLEPTGCIVEHPAEFTIDARAAGT-AELKIYAQDAEGSPIDIKIKDNGDNTYVCVYVPTKPIKHTIIITWGGVNIPNSPYRVSYSLIGLCFS---------------SPLFFRDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTV---KYTPPGAGKYTIMVLFADQEIPTSPFRVKVDPSHDASKVRAEGPGLNRTGVEVGKPTHFTVYTKGAGKAKLDVQFAGSIKGEAVQDFEIIDNHDYSYTVKYTAVQQGTLTVSVTYGGDPIPKSPFNVNVAPPLDLSKVKVQGLNNKVDVGKDQEFSIDTSGAGGQGKVDVKITSPSRRPIP-CKVETGVTSDIHTVKYMPPEEGPYKVDISYDGHPVPGSPFSVEAVMPPDSSKVRAYGPGLKGGFVGKPAPFAIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCSVSYLPTEPGEYSINILFAESHIPGSPFKADIRP-------VFDPSKVTASGPGLEKGKA--GEVATFTVDCSKA---GDAELTIEILSDSGSKAEVLIQNNSDGTYSITYIPACPGAYTITIKYGGHAVPKFPVRVNVEPAVDTSGVKVFGPGVEPRGVLREVTTEFTVDARSLTKTGGSHVTTRILGPSGAVTESFLSDNGDGTYHVQYTAYEDGVHLIEVLYDDVPVPKSPFRVPVTEGCDPSRVRAYGPGLE--GGLLNKSNRFTVETRGAGTGGLGLAIEGPSEAKMS----CKDNKDGSCSVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKEIVDPSKVKCSGPGL----GSGVRAHVPQTFTVDCSKAGLAPLEVLVQGPSGLAEPVDIRDNGDGTHTVNYTPATDGPYTVSVRYADQEVPRSPFKIKVLPTHDASK---VRASGPGLNTAGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRGNGDGTYTVSYVPDMAGRYTITIKYGGDEIPYSPFRIHAVP--------------TGDASKCLVTGEPAIGEETVITVDAKAAGKGKVTCKVSTPDGAELDVDVVENQDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVVVSKQEVMKSASKAPAATEEPVVPVENLDT--MLRPFNLVIPFTVQKGEITGEVRMPSGKTARPNITDNKDGTVTVKFAPVEKGLHEMDIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITC--KDNKDGTCTVSYMPTAPGDYNIIVRFDDKHIPGSPFTSKITGDDSMRTSQ-------LNVGTSTDVSLKITESD---LSLLTASIRAPSGNEEPCLLKRLPNRHIG---ISFTPKEVGEHVVSVKKNGKHVTNSPFKIMVG--PSE------IGDASKVKVSGKGLLEGVTFEVAEFIVDTRNAGYGGLGLSIEGPSKVDINCE--DMEDGTCKVSYCPTEPGTYIINIKFAEKHVPGSPFMVKV---TGEGRMKESITRRRQAPSIASIGSTCDLNLKIPEAGAQEMTAQVTSPSGQTADAEIIDGEDNTYSVRFVPQEMGAHTVSVKYRGQHVPGSPFQFTV--GPMGE------------GGAHKVRAGGPGLERGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFEDRKDGSCGVSYIVQEAGDYEVSIKFNDEHIPDSPFVVPVASRSDDARRLTVTSLQETGIIVNQPASFAVQLNGARGVIDAKVHTPSGMVEECYVSEVDSDKYSIRFIPRENGVHSIDVKFNG-RHIPGSPFKIRV-GEQSQAGD-------------------------PGLVTAYGLGLEGGVTGRPSEFIVSTLNAGAGSLSVTIDGPSKVKLDCQDSPEG---YKVSYTPMAPGNYLISIKYGGPQHIVGSPFKARV 2435
BLAST of Filamin vs. Ensembl Mouse
Match: Flnb (filamin, beta [Source:MGI Symbol;Acc:MGI:2446089]) HSP 1 Score: 1340.87 bits (3469), Expect = 0.000e+0 Identity = 869/2335 (37.22%), Postives = 1250/2335 (53.53%), Query Frame = 2 Query: 842 PKVD--EKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP----YKESKIKAFGPGL--TGGIVSKPAFFEVETNGETGALGFSIKGPSEAK---IDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPST-----VKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS----VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQET--NNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSV------------VDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX---------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGST-----QKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 PKV K ++ + Q + + ++ +V A GPGLE GN P F + T AG G++ I V +P+G K E+ Y C Y P G + + + FA IP SPF V + A +P+ ASG G++P G + F V T AG G + + KG ++ VK K + + EY G +SV V + G I SPF V V + + ++ A G G+ G V A+F V + + LG + GP ++ + + C + Y P+ PG Y V I + I SP+ + P Y ++A+GPGL +G ++ PA F V+ A + E + I DG+ +Y P ++ + ++ NIP SPY I + P KV +GPG+ SG+ N+P F V+ AG A + + I N + T++ +Y P PG++T+ V + + IP SPF+V V + +A+ +K GPG+ +A + T+F V K AG + + + E ++D+ ++ DN D + T+KYTP G + + + IP+SPF V + + D K KIN L N +G+ EF I T G + + ++ + SP+ VP + A F P G V V G+P+ SPY V A+ D K + P E L+ A++ ID K + P E + ++ N + S ++ P + Y V E KA++ P V A G GL G P +D +E P LG+ + +A++ +N DGT +V Y+P G Y + + Y E + P V + P D + + A+GPG+ VF+++ + FTV+++P+ G +KA ITNP + C V +N DGTY Y+P G H +++TYD VP+ SP+ V V +G PSR+ A GPGL+E T + FTV GAG GGLG+++EGP++++I C DNKDG+CS +Y+P PG YDV+I + HIPGSPF VP D+VD SKVK GPGL + R P FTVD+SKAG APL+V V+ V+P ++ G VTY P G + V Y + ++P SPF VL + + KV +G G+ + + +P F I+ RDAGE L + +T + V ++ DGT+ Y D G Y + V YG N+P SP+ + +C GP I V G+ V V+ + AG G ++ + P G + G + Y K G Y + + F +IPN A E ++E + +P + E V D P + V+ PS +K P +++N DGT+TV+Y P+E GLHE+ + Y G I SP +FYV+ SG V+AYGPGL YG + A FTIVT+DAG GGL LA+EGPSKAEI CIDNK+GTC V+YLP PGDY I +K+ DKHI GSPFTAKI + ++ SQ+ +G+ +D L ISETD++ L A + +P+GR+E C LKRL N ++GISF P+EVGEHLV++ ++G H+ NSP I V ++EIG+A R K+YG GL++G E F+VDTR+AGYGG+SL++EGPSKV+I+ D DGTC V+Y PT PG YI++ K+AD +VPGSPF V I G + E I R A V+ +G++C+LNL IP N + +A V SPSG EI+ + N +RF+P+E+GVHTVSVK +HVTGSPFQFTVGPL +GG HKV G G+ERG A +F+I+TREAGAG LSIA+EGPSKAEI F D+K+GSCGV+Y EPG+Y SIKFNDEH+P SP+++ PV + +D+R +++ +LQ+ G + A+F I +G G I A V SPS + +S+++ ++Y+V F+P ENGIH + V N S + GSPF+V V V+ G G+ G TG +EFF++T+ AG G L+VTI+GPSKV+++CQE GY Y P APG+Y I +KYGG NHI SPF ++G S S ET S L ++V S T K S V +G GL A +G+++ F+VD AG ++L +GV GP PCEEV++KH+G ++ V Y V+E+G ++L V+WG +PGSPF + VP Sbjct: 321 PKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQG-KNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEAC-NPNACRASGRGLQPKGVRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQK--GFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQVGPE---AGMQKVRAWGPGLH--GGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSC--DVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAGSAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSH---PQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPLPGEAVKDLDII--DNYDYSHTVKYTPTQQGNMQVL-VTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGG--LGLTVEGPCE-AKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAI-------DTSGIKAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLS-SCVRACIPQSFTVDSSKAGLAPLEVRVLG-PRGLVEPVNVVDNGD-GTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLS---AYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATD-GEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPESPLQFYVNYP-NSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDNRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISG--EGRVRESITRTSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLV------------PVIAPS---DDARCLTVLSLQESGLKVNQPASFAIRLNG-AKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 2602 HSP 2 Score: 1080.86 bits (2794), Expect = 0.000e+0 Identity = 854/2602 (32.82%), Postives = 1248/2602 (47.96%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHT-HKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYK-ESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS------VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNT---TPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAID-NKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQR----SNFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE--EGITKQPQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLER---NGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYS---VVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVD----STIPSGQVTAYGPGLSYGRP-----------DMHAH----FTIVTKDA-GAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVG---------TTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLII-----PGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLA----NDANQFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRX---XXXXXXXXXXXIHHGHTG-RINE--FFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWG--NHDVPGSPFEIVV 7621 + E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS H H+RP FR KLENV++ L FL+ E ++LV+IDS I D LKLILGL+WTLILHYSI+MP+WE ++ D K +PKQRLLGWI +K+P+ P+ NF +W DG A+GALVD+CAPGLCP+W WDP++ + NA+EA+ A++ L V +I P E+I+P VDE ++MTYLSQFP A+L APL PK N + RAYG G+E GN + PA FTVDT +AG+G++ + V +P+G KE + +K YS Y+P + G +++I+ FA I SPF+VNV A GD SKVTA GPG+E GN + T+F+++TA AG G + + D +G K+SV+ + + + Y + G H V V FAG I SPFGV + + N +A A+GRG+QP+GVR+R+ A+F+V T+ AG +LGV V GP E + K +Y Y P PG Y V + +G + I SPF V V P K++A+GPGL GGIV + A F VE+ G E G LGF+I+GPS+AKI+ D DGS +V YWP PGEYAVHI+CDDE+I SPYMA I T ++P V AYGPGL SG + N PA+FIV+ K+AGS + +K D GQ I +Q++ DGTY+C YTP KHT+ V +G VNIP SP++VN+ + + +KV+GPG+ER+ K N T+F VDC AG GD+ + VL + DV N + TF YTI++ F+ EIP SPF+V ++ +D K K + G+ F + T G K + SP L +N +TPT G V V G+PI SP+ V ++ + E + ++AID N A + + V L+P R V P R + F P EE ++ V T + E P V A+G GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP +PG Y VN+L+ + HI SPF I D +KV A GPGL V + + G G + + ++ ++ NN DGTY+ +Y P G + + + Y G V P +V V D S I+A+GPG+E + + FTVD L G + I P+ A +CF DN DGT V+Y P + G + V + +++ IP SPF V + + S+V GPGL+ N S V FTV AG L + V + + + G YIP G+ ++ + Y + +PGSPF + +P KV + G G+ + +P FT+++ AG + LE+ V GP ++V ++GDGT T Y G Y V V Y ++ +P SPF V V + GP L+ VP V ++ ++AG+G+L+ + G ++ + + G V+Y+P K G Y + + + +NIP R A Q + + + T P ++T VVD K V V+ P + +I N DGT + Y ++ G + + V + G I SPF + + V A PG RP DM+ F +V A G ++ V PS KA + +DNK+GT V Y P G + + IK+ HI SP + P S G T+ + + L+ + P+ E SC + +G +++ P G++ + V + +HIP SPF + ++ S+VKL F++D L+ SI+ PS + C +NH G +++ P E G +++++K ++V SP ++ + + Q +E G E++ I GY + +V PS E L D + + P GV+ VS K + HV GSPF + G +V + R A + E + +S + PS +AEI K+ C V + E G + S+K+ +HV GSPF + P + + + G A F I G +S V PS E + N V ++ E G + V + N+ IP SP+ V + + +G ++N+ F N G + + PS C +E Y ++P+ G +TI +K+ G +H++GSPF V + N P V G GL+ G ++EF ++ AG L V + GP + C+E+ ++V Y G +L+ V++G NH + SPF+ V Sbjct: 3 VTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDH-ESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWE----DEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQG-KNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQI-GEACNPNA--CRASGRGLQPKGVRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAGS-APLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTF-TVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAG-KAPLNVQFSSPLPGEAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTNGAGGQGKLDV--TILSP-SRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADI-------EMPFDPSKVVASGPGLEHGKVGEPGILCVDCSEA-----GPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSGIKAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNV-----FTVVTRGAGIGGLGITVEGPSESKIN----CRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLS----SCVRACIPQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQ-----TGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGK---GKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGF---RPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPESPLQFYV-NYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNK--DGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDN-RRCSQVKL----------GSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIG---ISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGQGLSE----GRTFEMSDFIVDTRDAGYG--GISLAVEGPSKVDIQTE--DLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKI-----SGEGRVRESITRTSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEI-VPMGKNSHC-VRFVPQEMGVHTVSVKYRGQHVTGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNG-SHVVGSPFKVRVGEPGQAGN--------------------------PALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEI------PEGYKVMYTPMAPGNYLIGVKYGGPNH-ISRSPFKAKV 2471
BLAST of Filamin vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556]) HSP 1 Score: 1162.13 bits (3005), Expect = 0.000e+0 Identity = 653/1512 (43.19%), Postives = 922/1512 (60.98%), Query Frame = 2 Query: 3212 NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAF---QPQEQYSI--ERTTHHYTTEQ--------SKPIIR------TEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXX---------XXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETK-----SLTQTV----HMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 V G GL + A F +D + A L + I E + A++ D+GDGT ++ Y+P PG+Y V + Y + + + P + + P D + V YGPG+ GVF+++ ++F+V+A+ + G VKA + NP + V + DGTY Y+P +G H +D+TYDG PV SP+ VPV +G DPSR+R +GPG++ G T +P KFTV+ GAG GGLGL++EGP++A++ C DNKDG+CSV+Y+P + G+Y +++ + +PGSPF VP+HD+ D SKVKC GPGL R P F VD SKAG APL+V V V+P ++ + G V Y+P G+ I VLY +VP SPF VL + + KV +G G+ + +P FTI+ +DAGE L + +T P + + ++ DGT+T Y DVPG YT+ + YG +P SP+ V +C + G I + +G+ I V+T+ AG G ++ P G+ V + G + Y + G Y + + F E++PN + A QP Q + ++ Y Q +P++ T D P + V PS + P + +N DGT+TV+Y PSE+GLHE+++ Y+ I GSP +FYVD + G +TAYGPGL++G + A FT+ TKDAG GGLSLA+EGPSKAEI C DN++GTC VSYLP+ PGDY I +K+ D+HI GSPFTA++ G+ R S + VG+ +D+P+ ISETD++ L A V+ P+GREE C LKRL+NG++GISF PKE GEHLV+V ++G+H+ +SP + + ++EIG+ASRV++ G GL++G E +F++DTR+AGYGGLSLSIEGPSKV+I D DGTC VTY PTEPG YIIN+K+AD +VPGSPF+V + G + E I R + A V+ IG+ C+L+L IP + ++ TA V SPSG EI+ ++ + IRF+P E+G+HTVSVK +HV GSPFQFTVGPL +GG HKV G G+ER +F I+TREAGAG L+IA+EGPSKAEI F+D KDGSCGV Y V EPGDY S+KFN+EH+P SPF++ P +S S D+R +++++LQ+ G + A+F ++ +G G+I A V SPS + +++ID ++Y+V F+P ENGI+ + V N + IPGSPF++ VGE V+ G G+ G TG EF V+TSNAG GAL+VTIDGPSKV+++CQE GY TY P APG Y ISIKYGG HI GSPF ++G SN S+ ET SLT+ H SG GP+ V +G GL A +G+++ F VD AG ++L VGV GP PCEE+ +KH+G+ + V+Y +++KG + L+V+WG+ +PGSP+ I+VP Sbjct: 1162 KVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAV-------DTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKV-QGPKGLVEPVDVVDNAD-GTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTG---VPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVD-YVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTG--EGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVV-----PVASPS----------GDARRLTVSSLQESGLKVNQPASFAVSLNG-AKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGP---GPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMVP 2639 HSP 2 Score: 1047.34 bits (2707), Expect = 0.000e+0 Identity = 822/2607 (31.53%), Postives = 1245/2607 (47.76%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTH-KRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP-YKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNT-TPIGQLNEFEILTPFDGS---KVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETET--PLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNEK-------------AELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP-QKFTVDLEGAGQGG---LGLSIEGPA----DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----------GEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRT-EYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKF--------YVDSTIPSGQ---------------------VTAYGPGLSYGRP-DMHAHFTIVTKDAGAGGLSLAVEGPSK--AEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF--------TAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIEC--HDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCE-LNLII----PGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQ--FTIYTREAGAGSLSIAIEGPSKA--EIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTG----RINE--FFVDTSNAGNGALTVTIDGPSKVQLNC---QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK + I +LQ DL+DGL+LI L++ LS H +RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W+ E+ + Q +PKQRLLGWI +K+P P+ NF+ DW G A+GALVD+CAPGLCP+W WD + + NA+EA+ A++ L + +I P E+++P VDE ++MTYLSQFP A+L APL PK N + RAYGPG+E GN + A FTV+T +AG+G + + V +P G +E ++ + +K +S Y+P + G +++ + FA I SPF+V V + GD SKVTA GPG+EP GN + T+F +FTA AG G V+ VI D G+K +V+P++ + ++ + Y EG+H+V+V FAGV I SP+ V V + + + A GRG+QP+GVRV++ A+F+V+T+ AG +L V V GP + E+ + K + +Y Y P PG Y V I +G I SPF V V K++A+GPGL GGIV K A F VE G + G LGFS++GPS+AKI+C D GDGS +V YWP GEYAVH+LC+ E+I SP+MA I+ + F P +V A GPGL +G++ NKPA+F V+ K+AG + ++ + D G ++ ++DN +GTYSC Y P+ P KHT +VS+G V+IP SPF+VNV + +KVYGPG+ + K + TYF VDC AG GD+ I + E D ++ +DN T +YTI + F++ P SP +V +E +D K K LN T +G+ F + G V+ + K V + + +N + + P GP V V G+ I SP+ V + ++ + + + + D K+ ++K+ + V P N F P EE Y V+ T + A + V A+G GL G A +PA F ID+ LG+T+EGP EA+++ +DNGDGTCSV+Y+P EPG Y +N+L+ D HI SPF + P D +KV GPGL +F V+ G + I + + + ++ DGT++ +Y P G + + I Y G PV P + V D S ++ YGPG+E +G+ ++ +F+VD Q G + + P+ D +Q D DGT V+Y P + G + V + ++ +P SPF VP+ + D S+V+ +GPG++ + P++FTV+ A G + K++ +D G V YIP G + V Y QVPGSPF V + + KV +G G+ P G + AN +P F ++T AG + L++ V GP +DV ++ DGT T Y G+Y++ VLYG + VP SPF V V + GP LN VP V ++ ++AG+G+L+ + P G I++ G TV+YVP G Y + + + + IP R A + + + T P I+ E +V+ V + DV ++ N DGT + Y + G + + V + G+ + SPF+ V + + S Q V G ++ RP D+ FTI G ++ V PS A+ DNK+GT V Y P G + + I++ + HI GSP I + V + + + L+ + P+ E SCT Q+G +S+ P G++ + V + +HIP SPF V ++ S +K V ++ L+ ++ PS E C +G +++ P E G ++++VK +V SP V I S S R + + + G+ E II GY + S+ PS E L D + + P E G + +++K ++HV GSPF V G K I +AN + ++ E ++ + PS E + + ++ + + + E G + S+K+ +HVPGSPF + P + + + +G A F I G ++ V PS E S + V +V E G + V V N IP SPF V V + + ++N+ F + N GA+ + PS C + ++ Y ++P G Y I +K+ G HI GSPF + + + + P V G GL+ G EFIV+ AG L V + GP + C+E ++V Y G +L+ +++G + + GSPF+ V Sbjct: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQ----TPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACR---AIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGP-KGEERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAGK-APLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTV---KYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDI-IDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLGDKVDVGKDQEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAP-------CFDASKVKCSGPGLE--RATAGEVGQFQVDCSSA---GSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQ--DCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTN--KPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKD--------------GSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSP--GMVRAN-LPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVP-----TGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDV-DVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTI-----KKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDN--QDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLK----------VGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVI----SQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYG--GLSLSIEGPSKVDINTE--DLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKV---TGEGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAE--ISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNG-THIPGSPFKIRVGEPGHGGD--------------------------PGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQEC------PEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2508 HSP 3 Score: 150.599 bits (379), Expect = 1.821e-35 Identity = 138/493 (27.99%), Postives = 219/493 (44.42%), Query Frame = 2 Query: 1037 NLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKN-AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESK----IKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHI-LCDDENIPKSPYMAQI------------QLDTKLFDPL--------------------KVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQ---IRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV 2389 ++ V +P G+ EI + N Y ++P G + + +K+ +P SPF+ V G KV A GPG+E EVG F ++T EAG G + + + S + + + + Y +E G + V+V F I SPF V V+S + DA++ T +Q G++V A F V A A + V+ P +LE+C + ++ Y +IP+ G Y++D+K+ I SPF + V + A+G GL GG+ PA F V T N GAL +I GPS+ K+DC + +G VTY P PG Y + I +I SP+ A++ + + D L KV A G GL S + ++F V+ AG+ + V G P + ++ YS Y K G++T++V +G+ +IP SP+++ V Sbjct: 2165 DMTAQVTSPSGKTHEAEIVEGENH--TYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERA--EVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFE----DRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSG--DARRL--TVSSLQESGLKVNQPASFAVSLNGAKGA-IDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGY-RVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGL-SKAYVGQKSNFTVDCSKAGNNMLL----VGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2638 HSP 4 Score: 91.6633 bits (226), Expect = 1.330e-17 Identity = 88/318 (27.67%), Postives = 134/318 (42.14%), Query Frame = 2 Query: 965 LELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA--GDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAG-VQIQSSPF-------------------GVMVSSKTSNSDAKQAYATG-----------RGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV 1816 L+ G + PA F V + N KG +D V +P G E C + + + Y+ +IP G Y I +KF + IP SPFK+ V GDP V+A G G+E G G F V T+ AG G++ I +K + D ++ + + YT G + +++ + G I SPF V V S T + Q +G +G+ V + F V AG L V V+GP E+ +K + LY SY+ + G Y + +K+G+ I SP+ + V Sbjct: 2332 LQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDK--YAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLE--GGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDC------QECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2638 HSP 5 Score: 62.003 bits (149), Expect = 1.636e-8 Identity = 61/227 (26.87%), Postives = 94/227 (41.41%), Query Frame = 2 Query: 944 VRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANS-EIPNSPFKVNVKN----------------------------------AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENK-FLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMV 1516 V AYG GLE G G+PA F V+T NAG G L + + P K C+ + P Y +Y P G Y I IK+ I SPFK V D SKV A G G+ VG+++ F V ++AG + +++ G + + + K ++ + + Y K++G +++ V + I SP+ +MV Sbjct: 2424 VSAYGAGLE--GGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQ--ECPE---GYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKA--YVGQKSNFTVDCSKAGN---NMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2638
BLAST of Filamin vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556]) HSP 1 Score: 1162.13 bits (3005), Expect = 0.000e+0 Identity = 653/1512 (43.19%), Postives = 922/1512 (60.98%), Query Frame = 2 Query: 3212 NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAF---QPQEQYSI--ERTTHHYTTEQ--------SKPIIR------TEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXX---------XXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETK-----SLTQTV----HMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 V G GL + A F +D + A L + I E + A++ D+GDGT ++ Y+P PG+Y V + Y + + + P + + P D + V YGPG+ GVF+++ ++F+V+A+ + G VKA + NP + V + DGTY Y+P +G H +D+TYDG PV SP+ VPV +G DPSR+R +GPG++ G T +P KFTV+ GAG GGLGL++EGP++A++ C DNKDG+CSV+Y+P + G+Y +++ + +PGSPF VP+HD+ D SKVKC GPGL R P F VD SKAG APL+V V V+P ++ + G V Y+P G+ I VLY +VP SPF VL + + KV +G G+ + +P FTI+ +DAGE L + +T P + + ++ DGT+T Y DVPG YT+ + YG +P SP+ V +C + G I + +G+ I V+T+ AG G ++ P G+ V + G + Y + G Y + + F E++PN + A QP Q + ++ Y Q +P++ T D P + V PS + P + +N DGT+TV+Y PSE+GLHE+++ Y+ I GSP +FYVD + G +TAYGPGL++G + A FT+ TKDAG GGLSLA+EGPSKAEI C DN++GTC VSYLP+ PGDY I +K+ D+HI GSPFTA++ G+ R S + VG+ +D+P+ ISETD++ L A V+ P+GREE C LKRL+NG++GISF PKE GEHLV+V ++G+H+ +SP + + ++EIG+ASRV++ G GL++G E +F++DTR+AGYGGLSLSIEGPSKV+I D DGTC VTY PTEPG YIIN+K+AD +VPGSPF+V + G + E I R + A V+ IG+ C+L+L IP + ++ TA V SPSG EI+ ++ + IRF+P E+G+HTVSVK +HV GSPFQFTVGPL +GG HKV G G+ER +F I+TREAGAG L+IA+EGPSKAEI F+D KDGSCGV Y V EPGDY S+KFN+EH+P SPF++ P +S S D+R +++++LQ+ G + A+F ++ +G G+I A V SPS + +++ID ++Y+V F+P ENGI+ + V N + IPGSPF++ VGE V+ G G+ G TG EF V+TSNAG GAL+VTIDGPSKV+++CQE GY TY P APG Y ISIKYGG HI GSPF ++G SN S+ ET SLT+ H SG GP+ V +G GL A +G+++ F VD AG ++L VGV GP PCEE+ +KH+G+ + V+Y +++KG + L+V+WG+ +PGSP+ I+VP Sbjct: 1162 KVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAV-------DTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKV-QGPKGLVEPVDVVDNAD-GTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTG---VPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVD-YVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTG--EGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVV-----PVASPS----------GDARRLTVSSLQESGLKVNQPASFAVSLNG-AKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGP---GPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMVP 2639 HSP 2 Score: 1047.34 bits (2707), Expect = 0.000e+0 Identity = 822/2607 (31.53%), Postives = 1245/2607 (47.76%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTH-KRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP-YKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNT-TPIGQLNEFEILTPFDGS---KVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETET--PLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNEK-------------AELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP-QKFTVDLEGAGQGG---LGLSIEGPA----DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----------GEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRT-EYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKF--------YVDSTIPSGQ---------------------VTAYGPGLSYGRP-DMHAHFTIVTKDAGAGGLSLAVEGPSK--AEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF--------TAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIEC--HDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCE-LNLII----PGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQ--FTIYTREAGAGSLSIAIEGPSKA--EIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTG----RINE--FFVDTSNAGNGALTVTIDGPSKVQLNC---QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK + I +LQ DL+DGL+LI L++ LS H +RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W+ E+ + Q +PKQRLLGWI +K+P P+ NF+ DW G A+GALVD+CAPGLCP+W WD + + NA+EA+ A++ L + +I P E+++P VDE ++MTYLSQFP A+L APL PK N + RAYGPG+E GN + A FTV+T +AG+G + + V +P G +E ++ + +K +S Y+P + G +++ + FA I SPF+V V + GD SKVTA GPG+EP GN + T+F +FTA AG G V+ VI D G+K +V+P++ + ++ + Y EG+H+V+V FAGV I SP+ V V + + + A GRG+QP+GVRV++ A+F+V+T+ AG +L V V GP + E+ + K + +Y Y P PG Y V I +G I SPF V V K++A+GPGL GGIV K A F VE G + G LGFS++GPS+AKI+C D GDGS +V YWP GEYAVH+LC+ E+I SP+MA I+ + F P +V A GPGL +G++ NKPA+F V+ K+AG + ++ + D G ++ ++DN +GTYSC Y P+ P KHT +VS+G V+IP SPF+VNV + +KVYGPG+ + K + TYF VDC AG GD+ I + E D ++ +DN T +YTI + F++ P SP +V +E +D K K LN T +G+ F + G V+ + K V + + +N + + P GP V V G+ I SP+ V + ++ + + + + D K+ ++K+ + V P N F P EE Y V+ T + A + V A+G GL G A +PA F ID+ LG+T+EGP EA+++ +DNGDGTCSV+Y+P EPG Y +N+L+ D HI SPF + P D +KV GPGL +F V+ G + I + + + ++ DGT++ +Y P G + + I Y G PV P + V D S ++ YGPG+E +G+ ++ +F+VD Q G + + P+ D +Q D DGT V+Y P + G + V + ++ +P SPF VP+ + D S+V+ +GPG++ + P++FTV+ A G + K++ +D G V YIP G + V Y QVPGSPF V + + KV +G G+ P G + AN +P F ++T AG + L++ V GP +DV ++ DGT T Y G+Y++ VLYG + VP SPF V V + GP LN VP V ++ ++AG+G+L+ + P G I++ G TV+YVP G Y + + + + IP R A + + + T P I+ E +V+ V + DV ++ N DGT + Y + G + + V + G+ + SPF+ V + + S Q V G ++ RP D+ FTI G ++ V PS A+ DNK+GT V Y P G + + I++ + HI GSP I + V + + + L+ + P+ E SCT Q+G +S+ P G++ + V + +HIP SPF V ++ S +K V ++ L+ ++ PS E C +G +++ P E G ++++VK +V SP V I S S R + + + G+ E II GY + S+ PS E L D + + P E G + +++K ++HV GSPF V G K I +AN + ++ E ++ + PS E + + ++ + + + E G + S+K+ +HVPGSPF + P + + + +G A F I G ++ V PS E S + V +V E G + V V N IP SPF V V + + ++N+ F + N GA+ + PS C + ++ Y ++P G Y I +K+ G HI GSPF + + + + P V G GL+ G EFIV+ AG L V + GP + C+E ++V Y G +L+ +++G + + GSPF+ V Sbjct: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQ----TPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACR---AIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGP-KGEERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAGK-APLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTV---KYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDI-IDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLGDKVDVGKDQEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAP-------CFDASKVKCSGPGLE--RATAGEVGQFQVDCSSA---GSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQ--DCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTN--KPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKD--------------GSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSP--GMVRAN-LPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVP-----TGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDV-DVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTI-----KKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDN--QDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLK----------VGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVI----SQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYG--GLSLSIEGPSKVDINTE--DLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKV---TGEGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAE--ISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNG-THIPGSPFKIRVGEPGHGGD--------------------------PGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQEC------PEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2508 HSP 3 Score: 150.599 bits (379), Expect = 1.821e-35 Identity = 138/493 (27.99%), Postives = 219/493 (44.42%), Query Frame = 2 Query: 1037 NLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKN-AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESK----IKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHI-LCDDENIPKSPYMAQI------------QLDTKLFDPL--------------------KVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQ---IRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV 2389 ++ V +P G+ EI + N Y ++P G + + +K+ +P SPF+ V G KV A GPG+E EVG F ++T EAG G + + + S + + + + Y +E G + V+V F I SPF V V+S + DA++ T +Q G++V A F V A A + V+ P +LE+C + ++ Y +IP+ G Y++D+K+ I SPF + V + A+G GL GG+ PA F V T N GAL +I GPS+ K+DC + +G VTY P PG Y + I +I SP+ A++ + + D L KV A G GL S + ++F V+ AG+ + V G P + ++ YS Y K G++T++V +G+ +IP SP+++ V Sbjct: 2165 DMTAQVTSPSGKTHEAEIVEGENH--TYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERA--EVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFE----DRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSG--DARRL--TVSSLQESGLKVNQPASFAVSLNGAKGA-IDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGY-RVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGL-SKAYVGQKSNFTVDCSKAGNNMLL----VGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2638 HSP 4 Score: 91.6633 bits (226), Expect = 1.330e-17 Identity = 88/318 (27.67%), Postives = 134/318 (42.14%), Query Frame = 2 Query: 965 LELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA--GDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAG-VQIQSSPF-------------------GVMVSSKTSNSDAKQAYATG-----------RGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV 1816 L+ G + PA F V + N KG +D V +P G E C + + + Y+ +IP G Y I +KF + IP SPFK+ V GDP V+A G G+E G G F V T+ AG G++ I +K + D ++ + + YT G + +++ + G I SPF V V S T + Q +G +G+ V + F V AG L V V+GP E+ +K + LY SY+ + G Y + +K+G+ I SP+ + V Sbjct: 2332 LQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDK--YAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLE--GGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDC------QECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2638 HSP 5 Score: 62.003 bits (149), Expect = 1.636e-8 Identity = 61/227 (26.87%), Postives = 94/227 (41.41%), Query Frame = 2 Query: 944 VRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANS-EIPNSPFKVNVKN----------------------------------AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENK-FLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMV 1516 V AYG GLE G G+PA F V+T NAG G L + + P K C+ + P Y +Y P G Y I IK+ I SPFK V D SKV A G G+ VG+++ F V ++AG + +++ G + + + K ++ + + Y K++G +++ V + I SP+ +MV Sbjct: 2424 VSAYGAGLE--GGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQ--ECPE---GYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKA--YVGQKSNFTVDCSKAGN---NMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2638
BLAST of Filamin vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556]) HSP 1 Score: 1159.05 bits (2997), Expect = 0.000e+0 Identity = 650/1493 (43.54%), Postives = 915/1493 (61.29%), Query Frame = 2 Query: 3212 NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXX---------XXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETK-----SLTQTV----HMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 V G GL + A F +D + A L + I E + A++ D+GDGT ++ Y+P PG+Y V + Y + + + P + + P D + V YGPG+ GVF+++ ++F+V+A+ + G VKA + NP + V + DGTY Y+P +G H +D+TYDG PV SP+ VPV +G DPSR+R +GPG++ G T +P KFTV+ GAG GGLGL++EGP++A++ C DNKDG+CSV+Y+P + G+Y +++ + +PGSPF VP+HD+ D SKVKC GPGL R P F VD SKAG APL+V V V+P ++ + G V Y+P G+ I VLY +VP SPF VL + + KV +G G+ + +P FTI+ +DAGE L + +T P + + ++ DGT+T Y DVPG YT+ + YG +P SP+ V +C + G I + +G+ I V+T+ AG G ++ P G+ V + G + Y + G Y + + F E++PN Q +I +R V+ F G + VR PS + P + +N DGT+TV+Y PSE+GLHE+++ Y+ I GSP +FYVD + G +TAYGPGL++G + A FT+ TKDAG GGLSLA+EGPSKAEI C DN++GTC VSYLP+ PGDY I +K+ D+HI GSPFTA++ G+ R S + VG+ +D+P+ ISETD++ L A V+ P+GREE C LKRL+NG++GISF PKE GEHLV+V ++G+H+ +SP + + ++EIG+ASRV++ G GL++G E +F++DTR+AGYGGLSLSIEGPSKV+I D DGTC VTY PTEPG YIIN+K+AD +VPGSPF+V + G + E I R + A V+ IG+ C+L+L IP + ++ TA V SPSG EI+ ++ + IRF+P E+G+HTVSVK +HV GSPFQFTVGPL +GG HKV G G+ER +F I+TREAGAG L+IA+EGPSKAEI F+D KDGSCGV Y V EPGDY S+KFN+EH+P SPF++ P +S S D+R +++++LQ+ G + A+F ++ +G G+I A V SPS + +++ID ++Y+V F+P ENGI+ + V N + IPGSPF++ VGE V+ G G+ G TG EF V+TSNAG GAL+VTIDGPSKV+++CQE GY TY P APG Y ISIKYGG HI GSPF ++G SN S+ ET SLT+ H SG GP+ V +G GL A +G+++ F VD AG ++L VGV GP PCEE+ +KH+G+ + V+Y +++KG + L+V+WG+ +PGSP+ I+VP Sbjct: 1138 KVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAV-------DTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKV-QGPKGLVEPVDVVDNAD-GTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTG---VPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPF---------QVTIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRM----PSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVD-YVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTG--EGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVV-----PVASPS----------GDARRLTVSSLQESGLKVNQPASFAVSLNG-AKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGP---GPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMVP 2583 HSP 2 Score: 1057.74 bits (2734), Expect = 0.000e+0 Identity = 822/2579 (31.87%), Postives = 1243/2579 (48.20%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTH-KRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVA-PYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNT-TPIGQLNEFEILTPFDGS---KVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETET--PLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNEK-------------AELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP-QKFTVDLEGAGQGG---LGLSIEGPA----DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----------GEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRT-EYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSG-QVTAYGPGLSYGRP-DMHAHFTIVTKDAGAGGLSLAVEGPSK--AEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF--------TAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIEC--HDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCE-LNLII----PGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQ--FTIYTREAGAGSLSIAIEGPSKA--EIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTG----RINE--FFVDTSNAGNGALTVTIDGPSKVQLNC---QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK + I +LQ DL+DGL+LI L++ LS H +RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W+ E+ + Q +PKQRLLGWI +K+P P+ NF+ DW G A+GALVD+CAPGLCP+W WD + + NA+EA+ A++ L + +I P E+++P VDE ++MTYLSQFP A+L APL PK N + RAYGPG+E GN + A FTV+T +AG+G + + V +P G +E ++ + +K +S Y+P + G +++ + FA I SPF+V V + GD SKVTA GPG+EP GN + T+F +FTA AG G V+ VI D G+K +V+P++ + ++ + Y EG+H+V+V FAGV I SP+ V V + + + A GRG+QP+GVRV++ A+F+V+T+ AG +L V V GP + E+ + K + +Y Y P PG Y V I +G I SPF V V K++A+GPGL GGIV K A F VE G + G LGFS++GPS+AKI+C D GDGS +V YWP GEYAVH+LC+ E+I SP+MA I+ + F P +V A GPGL +G++ NKPA+F V+ K+AG + ++ + D G ++ ++DN +GTYSC Y P+ P KHT +VS+G V+IP SPF+VNV + +KVYGPG+ + K + TYF VDC AG GD+ I + E D ++ +DN T +YTI + F++ P SP +V +E +D K K LN T +G+ F + G V+ + K V + + +N + + P GP V V G+ I SP+ V + ++ + + + + D K+ ++K+ + V P N F P EE Y V+ T + A + V A+G GL G A +PA F ID+ LG+T+EGP EA+++ +DNGDGTCSV+Y+P EPG Y +N+L+ D HI SPF + P D +KV GPGL +F V+ G + I + + + ++ DGT++ +Y P G + + I Y G PV P + V D S ++ YGPG+E +G+ ++ +F+VD Q G + + P+ D +Q D DGT V+Y P + G + V + ++ +P SPF VP+ + D S+V+ +GPG++ + P++FTV+ A G + K++ +D S V YIP G + V Y QVPGSPF V + + KV +G G+ P G + AN +P F ++T AG + L++ V GP +DV ++ DGT T Y G+Y++ VLYG + VP SPF V V + GP LN VP V ++ ++AG+G+L+ + P G I++ G TV+YVP G Y + + + + IP R A + + + T P I+ E +V+ V + DV ++ N DGT + Y + G + + V + G+ + SPF+ TIP V G ++ RP D+ FTI G ++ V PS A+ DNK+GT V Y P G + + I++ + HI GSP I + V + + + L+ + P+ E SCT Q+G +S+ P G++ + V + +HIP SPF V ++ S +K V ++ L+ ++ PS E C +G +++ P E G ++++VK +V SP V I S S R + + + G+ E II GY + S+ PS E L D + + P E G + +++K ++HV GSPF V G K I +AN + ++ E ++ + PS E + + ++ + + + E G + S+K+ +HVPGSPF + P + + + +G A F I G ++ V PS E S + V +V E G + V V N IP SPF V V + + ++N+ F + N GA+ + PS C + ++ Y ++P G Y I +K+ G HI GSPF + + + + P V G GL+ G EFIV+ AG L V + GP + C+E ++V Y G +L+ +++G + + GSPF+ V Sbjct: 8 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQ----TPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACR---AIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGP-KGEERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAGK-APLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTV---KYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDI-IDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLGDKVDVGKDQEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAP-------CFDASKVKCSGPGLE--RATAGEVGQFQVDCSSA---GSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQ--DCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTN--KPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCS--------------VEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSP--GMVRAN-LPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVP-----TGDASKCTVTGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDV-DVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQV----TIPERPMVGVNGLDVTSLRPFDLVIPFTI-----KKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDN--QDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLK----------VGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVI----SQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYG--GLSLSIEGPSKVDINTE--DLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKV---TGEGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAE--ISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNG-THIPGSPFKIRVGEPGHGGD--------------------------PGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQEC------PEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2452 HSP 3 Score: 182.956 bits (463), Expect = 3.347e-45 Identity = 211/838 (25.18%), Postives = 349/838 (41.65%), Query Frame = 2 Query: 5276 QVTAYGPGL--SYGRPDMHAHFTIVTKDAGAGGLSLAVEGPS----KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICV------------GTTSDVPLRISETDINNLNAIVISPTGREESC--TLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDG--MVNETCQFVVDTRNAGYGGLSLSIEGPSKVE-IECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPL-IDGGPHKVHIMGSGVER-GLA-NDANQFTIYTREAGAGSLSIAI---EGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDE----NPYSSYSKPVKNENIIFNDSRYISIAALQ-DQG-FNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG--------HTGRINEFFVDTSNAGNGALTVTIDGPSKVQLN-----CQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGD----VLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPF--EIVVPN 7627 + AYGPG+ + A FT+ T+ AG G + + VE P+ +A++ ++KN T V Y+P G + + + F +HI SPF + S++ T+ + + + + ++ PTG++ + L+ + S+ P G H V+V +G IP SP+ + VG+ N + + G GL V ET F V T+ AG G L ++++GP E ++ D DG Y PT PGTY + + + N+ SPF V +G + +++ E +G + + G + SV PS + C+ D +R+ P+E G + V V ++ + SPF + D P +V G G+E+ G+A N +FT+ + AG L + + EG S E +DN +G+ +Y +P + + + +P SPF + + N Y V + ++ Y ++ + QG +IG K + V+ P+ + I + DN+ ++V + P G + + VL + P SP RV V + + G G+ F V+ AG G L V G +K +++ Y Y+P G +++ YGG +HI SPF V +S S+ +K +K G G KV ++GK EF V + AGG V SG PC+ LG + V + +E+G + + V + VPGSPF E V P Sbjct: 259 KARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQ--ACNPAACRAIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVG---TECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECD--DKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAGKAPLRVQVQDNEGCS-VEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKC--------------APGVVGPTEADIDFDIIRNDNDTFTVKYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDIIDHHDNTYTVKYIPVQQGPVGVNVTYGG-DHIPKSPFSVGVS-------PSLDLSK----------------------IKVSGLGDKV-DVGKDQEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVE--PGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPT 1041 HSP 4 Score: 150.599 bits (379), Expect = 1.901e-35 Identity = 138/488 (28.28%), Postives = 217/488 (44.47%), Query Frame = 2 Query: 1052 VLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKN-AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESK----IKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHI-LCDDENIPKSPYMAQI------------QLDTKLFDPL--------------------KVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQ---IRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV 2389 V +P G+ EI + N Y ++P G + + +K+ +P SPF+ V G KV A GPG+E EVG F ++T EAG G + + + S + + + + Y +E G + V+V F I SPF V V+S + DA++ T +Q G++V A F V A A + V+ P +LE+C + ++ Y +IP+ G Y++D+K+ I SPF + V + A+G GL GG+ PA F V T N GAL +I GPS+ K+DC + +G VTY P PG Y + I +I SP+ A++ + + D L KV A G GL S + ++F V+ AG+ + V G P + ++ YS Y K G++T++V +G+ +IP SP+++ V Sbjct: 2114 VTSPSGKTHEAEIVEGENH--TYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERA--EVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFE----DRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSG--DARRL--TVSSLQESGLKVNQPASFAVSLNGAKGA-IDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGY-RVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGL-SKAYVGQKSNFTVDCSKAGNNMLL----VGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2582 HSP 5 Score: 91.6633 bits (226), Expect = 1.381e-17 Identity = 88/318 (27.67%), Postives = 134/318 (42.14%), Query Frame = 2 Query: 965 LELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA--GDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAG-VQIQSSPF-------------------GVMVSSKTSNSDAKQAYATG-----------RGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV 1816 L+ G + PA F V + N KG +D V +P G E C + + + Y+ +IP G Y I +KF + IP SPFK+ V GDP V+A G G+E G G F V T+ AG G++ I +K + D ++ + + YT G + +++ + G I SPF V V S T + Q +G +G+ V + F V AG L V V+GP E+ +K + LY SY+ + G Y + +K+G+ I SP+ + V Sbjct: 2276 LQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDK--YAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLE--GGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDC------QECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2582 HSP 6 Score: 61.6178 bits (148), Expect = 1.731e-8 Identity = 61/227 (26.87%), Postives = 94/227 (41.41%), Query Frame = 2 Query: 944 VRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANS-EIPNSPFKVNVKN----------------------------------AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENK-FLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMV 1516 V AYG GLE G G+PA F V+T NAG G L + + P K C+ + P Y +Y P G Y I IK+ I SPFK V D SKV A G G+ VG+++ F V ++AG + +++ G + + + K ++ + + Y K++G +++ V + I SP+ +MV Sbjct: 2368 VSAYGAGLE--GGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQ--ECPE---GYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKA--YVGQKSNFTVDCSKAGN---NMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2582
BLAST of Filamin vs. Ensembl Mouse
Match: Flna (filamin, alpha [Source:MGI Symbol;Acc:MGI:95556]) HSP 1 Score: 1156.35 bits (2990), Expect = 0.000e+0 Identity = 652/1520 (42.89%), Postives = 921/1520 (60.59%), Query Frame = 2 Query: 3212 NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE---------VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAF---QPQEQYSI--ERTTHHYTTEQ--------SKPIIR------TEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXX---------XXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETK-----SLTQTV----HMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 V G GL + A F +D + A L + I E + A++ D+GDGT ++ Y+P PG+Y V + Y + + + P + + P D + V YGPG+ GVF+++ ++F+V+A+ + G VKA + NP + V + DGTY Y+P +G H +D+TYDG PV SP+ VPV +G DPSR+R +GPG++ G T +P KFTV+ GAG GGLGL++EGP++A++ C DNKDG+CSV+Y+P + G+Y +++ + +PGSPF VP+HD+ D SKVKC GPGL R P F VD SKAG APL+V V V+P ++ + G V Y+P G+ I VLY +VP SPF VL + + KV +G G+ + +P FTI+ +DAGE L + +T P + + ++ DGT+T Y DVPG YT+ + YG +P SP+ V +C + I + +G+ I V+T+ AG G ++ P G+ V + G + Y + G Y + + F E++PN + A QP Q + ++ Y Q +P++ T D P + V PS + P + +N DGT+TV+Y PSE+GLHE+++ Y+ I GSP +FYVD + G +TAYGPGL++G + A FT+ TKDAG GGLSLA+EGPSKAEI C DN++GTC VSYLP+ PGDY I +K+ D+HI GSPFTA++ G+ R S + VG+ +D+P+ ISETD++ L A V+ P+GREE C LKRL+NG++GISF PKE GEHLV+V ++G+H+ +SP + + ++EIG+ASRV++ G GL++G E +F++DTR+AGYGGLSLSIEGPSKV+I D DGTC VTY PTEPG YIIN+K+AD +VPGSPF+V + G + E I R + A V+ IG+ C+L+L IP + ++ TA V SPSG EI+ ++ + IRF+P E+G+HTVSVK +HV GSPFQFTVGPL +GG HKV G G+ER +F I+TREAGAG L+IA+EGPSKAEI F+D KDGSCGV Y V EPGDY S+KFN+EH+P SPF++ P +S S D+R +++++LQ+ G + A+F ++ +G G+I A V SPS + +++ID ++Y+V F+P ENGI+ + V N + IPGSPF++ VGE V+ G G+ G TG EF V+TSNAG GAL+VTIDGPSKV+++CQE GY TY P APG Y ISIKYGG HI GSPF ++G SN S+ ET SLT+ H SG GP+ V +G GL A +G+++ F VD AG ++L VGV GP PCEE+ +KH+G+ + V+Y +++KG + L+V+WG+ +PGSP+ I+VP Sbjct: 1162 KVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAV-------DTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKV-QGPKGLVEPVDVVDNAD-GTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTG---VPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVD-YVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTG--EGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVV-----PVASPS----------GDARRLTVSSLQESGLKVNQPASFAVSLNG-AKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGP---GPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMVP 2647 HSP 2 Score: 1047.73 bits (2708), Expect = 0.000e+0 Identity = 823/2610 (31.53%), Postives = 1244/2610 (47.66%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTH-KRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP-YKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNT-TPIGQLNEFEILTPFDGS---KVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETET--PLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNEK-------------AELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP-QKFTVDLEGAGQGG---LGLSIEGPA----DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----------GEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTH---HYTTEQSKPIIRT-EYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKF--------YVDSTIPSGQ---------------------VTAYGPGLSYGRP-DMHAHFTIVTKDAGAGGLSLAVEGPSK--AEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF--------TAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIEC--HDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCE-LNLII----PGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQ--FTIYTREAGAGSLSIAIEGPSKA--EIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTG----RINE--FFVDTSNAGNGALTVTIDGPSKVQLNC---QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK + I +LQ DL+DGL+LI L++ LS H +RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W+ E+ + Q +PKQRLLGWI +K+P P+ NF+ DW G A+GALVD+CAPGLCP+W WD + + NA+EA+ A++ L + +I P E+++P VDE ++MTYLSQFP A+L APL PK N + RAYGPG+E GN + A FTV+T +AG+G + + V +P G +E ++ + +K +S Y+P + G +++ + FA I SPF+V V + GD SKVTA GPG+EP GN + T+F +FTA AG G V+ VI D G+K +V+P++ + ++ + Y EG+H+V+V FAGV I SP+ V V + + + A GRG+QP+GVRV++ A+F+V+T+ AG +L V V GP + E+ + K + +Y Y P PG Y V I +G I SPF V V K++A+GPGL GGIV K A F VE G + G LGFS++GPS+AKI+C D GDGS +V YWP GEYAVH+LC+ E+I SP+MA I+ + F P +V A GPGL +G++ NKPA+F V+ K+AG + ++ + D G ++ ++DN +GTYSC Y P+ P KHT +VS+G V+IP SPF+VNV + +KVYGPG+ + K + TYF VDC AG GD+ I + E D ++ +DN T +YTI + F++ P SP +V +E +D K K LN T +G+ F + G V+ + K V + + +N + + P GP V V G+ I SP+ V + ++ + + + + D K+ ++K+ + V P N F P EE Y V+ T + A + V A+G GL G A +PA F ID+ LG+T+EGP EA+++ +DNGDGTCSV+Y+P EPG Y +N+L+ D HI SPF + P D +KV GPGL +F V+ G + I + + + ++ DGT++ +Y P G + + I Y G PV P + V D S ++ YGPG+E +G+ ++ +F+VD Q G + + P+ D +Q D DGT V+Y P + G + V + ++ +P SPF VP+ + D S+V+ +GPG++ + P++FTV+ A G + K++ +D G V YIP G + V Y QVPGSPF V + + KV +G G+ P G + AN +P F ++T AG + L++ V GP +DV ++ DGT T Y G+Y++ VLYG + VP SPF V V + GP LN VP V ++ ++AG+G+L+ + P G I++ G TV+YVP G Y + + + + IP R A + T H P I+ E +V+ V + DV ++ N DGT + Y + G + + V + G+ + SPF+ V + + S Q V G ++ RP D+ FTI G ++ V PS A+ DNK+GT V Y P G + + I++ + HI GSP I + V + + + L+ + P+ E SCT Q+G +S+ P G++ + V + +HIP SPF V ++ S +K V ++ L+ ++ PS E C +G +++ P E G ++++VK +V SP V I S S R + + + G+ E II GY + S+ PS E L D + + P E G + +++K ++HV GSPF V G K I +AN + ++ E ++ + PS E + + ++ + + + E G + S+K+ +HVPGSPF + P + + + +G A F I G ++ V PS E S + V +V E G + V V N IP SPF V V + + ++N+ F + N GA+ + PS C + ++ Y ++P G Y I +K+ G HI GSPF + + + + P V G GL+ G EFIV+ AG L V + GP + C+E ++V Y G +L+ +++G + + GSPF+ V Sbjct: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQ----TPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACR---AIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGP-KGEERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAGK-APLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTV---KYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDI-IDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLGDKVDVGKDQEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAP-------CFDASKVKCSGPGLE--RATAGEVGQFQVDCSSA---GSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQ--DCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTN--KPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKD--------------GSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSP--GMVRAN-LPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDV-DVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTI-----KKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDN--QDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLK----------VGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVI----SQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYG--GLSLSIEGPSKVDINTE--DLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKV---TGEGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAE--ISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNG-THIPGSPFKIRVGEPGHGGD--------------------------PGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQEC------PEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2516 HSP 3 Score: 92.0485 bits (227), Expect = 1.308e-17 Identity = 88/318 (27.67%), Postives = 134/318 (42.14%), Query Frame = 2 Query: 965 LELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA--GDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAG-VQIQSSPF-------------------GVMVSSKTSNSDAKQAYATG-----------RGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV 1816 L+ G + PA F V + N KG +D V +P G E C + + + Y+ +IP G Y I +KF + IP SPFK+ V GDP V+A G G+E G G F V T+ AG G++ I +K + D ++ + + YT G + +++ + G I SPF V V S T + Q +G +G+ V + F V AG L V V+GP E+ +K + LY SY+ + G Y + +K+G+ I SP+ + V Sbjct: 2340 LQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDK--YAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLE--GGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMD------CQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2646
BLAST of Filamin vs. UniProt/SwissProt
Match: sp|Q80X90|FLNB_MOUSE (Filamin-B OS=Mus musculus OX=10090 GN=Flnb PE=1 SV=3) HSP 1 Score: 1340.87 bits (3469), Expect = 0.000e+0 Identity = 869/2335 (37.22%), Postives = 1250/2335 (53.53%), Query Frame = 2 Query: 842 PKVD--EKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP----YKESKIKAFGPGL--TGGIVSKPAFFEVETNGETGALGFSIKGPSEAK---IDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPST-----VKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS----VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQET--NNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSV------------VDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX---------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGST-----QKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 PKV K ++ + Q + + ++ +V A GPGLE GN P F + T AG G++ I V +P+G K E+ Y C Y P G + + + FA IP SPF V + A +P+ ASG G++P G + F V T AG G + + KG ++ VK K + + EY G +SV V + G I SPF V V + + ++ A G G+ G V A+F V + + LG + GP ++ + + C + Y P+ PG Y V I + I SP+ + P Y ++A+GPGL +G ++ PA F V+ A + E + I DG+ +Y P ++ + ++ NIP SPY I + P KV +GPG+ SG+ N+P F V+ AG A + + I N + T++ +Y P PG++T+ V + + IP SPF+V V + +A+ +K GPG+ +A + T+F V K AG + + + E ++D+ ++ DN D + T+KYTP G + + + IP+SPF V + + D K KIN L N +G+ EF I T G + + ++ + SP+ VP + A F P G V V G+P+ SPY V A+ D K + P E L+ A++ ID K + P E + ++ N + S ++ P + Y V E KA++ P V A G GL G P +D +E P LG+ + +A++ +N DGT +V Y+P G Y + + Y E + P V + P D + + A+GPG+ VF+++ + FTV+++P+ G +KA ITNP + C V +N DGTY Y+P G H +++TYD VP+ SP+ V V +G PSR+ A GPGL+E T + FTV GAG GGLG+++EGP++++I C DNKDG+CS +Y+P PG YDV+I + HIPGSPF VP D+VD SKVK GPGL + R P FTVD+SKAG APL+V V+ V+P ++ G VTY P G + V Y + ++P SPF VL + + KV +G G+ + + +P F I+ RDAGE L + +T + V ++ DGT+ Y D G Y + V YG N+P SP+ + +C GP I V G+ V V+ + AG G ++ + P G + G + Y K G Y + + F +IPN A E ++E + +P + E V D P + V+ PS +K P +++N DGT+TV+Y P+E GLHE+ + Y G I SP +FYV+ SG V+AYGPGL YG + A FTIVT+DAG GGL LA+EGPSKAEI CIDNK+GTC V+YLP PGDY I +K+ DKHI GSPFTAKI + ++ SQ+ +G+ +D L ISETD++ L A + +P+GR+E C LKRL N ++GISF P+EVGEHLV++ ++G H+ NSP I V ++EIG+A R K+YG GL++G E F+VDTR+AGYGG+SL++EGPSKV+I+ D DGTC V+Y PT PG YI++ K+AD +VPGSPF V I G + E I R A V+ +G++C+LNL IP N + +A V SPSG EI+ + N +RF+P+E+GVHTVSVK +HVTGSPFQFTVGPL +GG HKV G G+ERG A +F+I+TREAGAG LSIA+EGPSKAEI F D+K+GSCGV+Y EPG+Y SIKFNDEH+P SP+++ PV + +D+R +++ +LQ+ G + A+F I +G G I A V SPS + +S+++ ++Y+V F+P ENGIH + V N S + GSPF+V V V+ G G+ G TG +EFF++T+ AG G L+VTI+GPSKV+++CQE GY Y P APG+Y I +KYGG NHI SPF ++G S S ET S L ++V S T K S V +G GL A +G+++ F+VD AG ++L +GV GP PCEEV++KH+G ++ V Y V+E+G ++L V+WG +PGSPF + VP Sbjct: 321 PKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQG-KNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQIGEAC-NPNACRASGRGLQPKGVRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQK--GFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQVGPE---AGMQKVRAWGPGLH--GGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSC--DVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAGSAPLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSH---PQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTFTVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAGKAPLNVQFSSPLPGEAVKDLDII--DNYDYSHTVKYTPTQQGNMQVL-VTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTNGAGGQGKLDVTILSPSRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGG--LGLTVEGPCE-AKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEPGILCVDCSEAGPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAI-------DTSGIKAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLS-SCVRACIPQSFTVDSSKAGLAPLEVRVLG-PRGLVEPVNVVDNGD-GTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLS---AYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQTGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGKGKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATD-GEVTAMEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPESPLQFYVNYP-NSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDNRRCSQVKLGSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGQGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISG--EGRVRESITRTSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLV------------PVIAPS---DDARCLTVLSLQESGLKVNQPASFAIRLNG-AKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEIPEGYKVMYTPMAPGNYLIGVKYGGPNHISRSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKSSSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGKQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 2602 HSP 2 Score: 1080.86 bits (2794), Expect = 0.000e+0 Identity = 854/2602 (32.82%), Postives = 1248/2602 (47.96%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHT-HKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYK-ESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS------VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNT---TPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAID-NKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQR----SNFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE--EGITKQPQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLER---NGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYS---VVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVD----STIPSGQVTAYGPGLSYGRP-----------DMHAH----FTIVTKDA-GAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVG---------TTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLII-----PGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLA----NDANQFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRX---XXXXXXXXXXXIHHGHTG-RINE--FFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWG--NHDVPGSPFEIVV 7621 + E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS H H+RP FR KLENV++ L FL+ E ++LV+IDS I D LKLILGL+WTLILHYSI+MP+WE ++ D K +PKQRLLGWI +K+P+ P+ NF +W DG A+GALVD+CAPGLCP+W WDP++ + NA+EA+ A++ L V +I P E+I+P VDE ++MTYLSQFP A+L APL PK N + RAYG G+E GN + PA FTVDT +AG+G++ + V +P+G KE + +K YS Y+P + G +++I+ FA I SPF+VNV A GD SKVTA GPG+E GN + T+F+++TA AG G + + D +G K+SV+ + + + Y + G H V V FAG I SPFGV + + N +A A+GRG+QP+GVR+R+ A+F+V T+ AG +LGV V GP E + K +Y Y P PG Y V + +G + I SPF V V P K++A+GPGL GGIV + A F VE+ G E G LGF+I+GPS+AKI+ D DGS +V YWP PGEYAVHI+CDDE+I SPYMA I T ++P V AYGPGL SG + N PA+FIV+ K+AGS + +K D GQ I +Q++ DGTY+C YTP KHT+ V +G VNIP SP++VN+ + + +KV+GPG+ER+ K N T+F VDC AG GD+ + VL + DV N + TF YTI++ F+ EIP SPF+V ++ +D K K + G+ F + T G K + SP L +N +TPT G V V G+PI SP+ V ++ + E + ++AID N A + + V L+P R V P R + F P EE ++ V T + E P V A+G GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP +PG Y VN+L+ + HI SPF I D +KV A GPGL V + + G G + + ++ ++ NN DGTY+ +Y P G + + + Y G V P +V V D S I+A+GPG+E + + FTVD L G + I P+ A +CF DN DGT V+Y P + G + V + +++ IP SPF V + + S+V GPGL+ N S V FTV AG L + V + + + G YIP G+ ++ + Y + +PGSPF + +P KV + G G+ + +P FT+++ AG + LE+ V GP ++V ++GDGT T Y G Y V V Y ++ +P SPF V V + GP L+ VP V ++ ++AG+G+L+ + G ++ + + G V+Y+P K G Y + + + +NIP R A Q + + + T P ++T VVD K V V+ P + +I N DGT + Y ++ G + + V + G I SPF + + V A PG RP DM+ F +V A G ++ V PS KA + +DNK+GT V Y P G + + IK+ HI SP + P S G T+ + + L+ + P+ E SC + +G +++ P G++ + V + +HIP SPF + ++ S+VKL F++D L+ SI+ PS + C +NH G +++ P E G +++++K ++V SP ++ + + Q +E G E++ I GY + +V PS E L D + + P GV+ VS K + HV GSPF + G +V + R A + E + +S + PS +AEI K+ C V + E G + S+K+ +HV GSPF + P + + + G A F I G +S V PS E + N V ++ E G + V + N+ IP SP+ V + + +G ++N+ F N G + + PS C +E Y ++P+ G +TI +K+ G +H++GSPF V + N P V G GL+ G ++EF ++ AG L V + GP + C+E+ ++V Y G +L+ V++G NH + SPF+ V Sbjct: 3 VTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMHHKYHQRPTFRQMKLENVSVALEFLDH-ESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWE----DEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPRKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEARVTPDSDKNKTYSVEYLPKVTGLHKVIVLFAGQHISKSPFEVNVDKAQGDASKVTAKGPGLETTGNIANKPTYFDIYTAGAGVGDIGIEVEDPQG-KNSVELLVEDRGNQVYRCVYKPVQPGPHVVKVSFAGDAIPKSPFGVQI-GEACNPNA--CRASGRGLQPKGVRIRETADFKVDTKAAGSGELGVTVKGPKGLEELVKQKGFLDGVYSFEYYPSTPGKYSVAVTWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGTLGFAIEGPSQAKIEYDDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGDYNPDLVQAYGPGLEKSGCTINNPAEFIVDPKDAGS-APLKILAQDGEGQPIDIQMKSRMDGTYACSYTPLKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSDDEEDVDFDIIHNANDTF-TVKYVPPAPGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVHTKGAG-KAPLNVQFSSPLPGEAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKINGLENRVEVGKDQEFAIDTNGAGGQGKLDV--TILSP-SRKVVPCLVAPVAGRECSTAKFIPREEGLFAVDVTYDGHPVPGSPYTVEASLPPDPTKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADI-------EMPFDPSKVVASGPGLEHGKVGEPGILCVDCSEA-----GPGTLGLEAVSDSGAKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPAWVKVEPAIDTSGIKAFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAQITNPSGASTECFVKDNADGTYQVEYTPFEKGFHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVHAQGPGLKEAFTNKSNV-----FTVVTRGAGIGGLGITVEGPSESKIN----CRDNKDGSCSAEYIPFAPGDYDVNITYGGVHIPGSPFRVPSKDVVDPSKVKIAGPGLS----SCVRACIPQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYIVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSAYGVPASLPVEFAIDARDAGEGLLAVQITDQEGKPQRATVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDNIPLSPYRIRATQ-----TGDASKCLATGPGIAPTVKTGEEVGFVVDAKTAGK---GKVTCVILTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAMEEAPVNACPPGF---RPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGTVHMPSGKKATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYRGSHIPESPLQFYV-NYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNK--DGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDN-RRCSQVKL----------GSAADFLLDISETDLSTLTASIKAPSGRDEPCLLKRLPNNHIG---ISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGQGLSE----GRTFEMSDFIVDTRDAGYG--GISLAVEGPSKVDIQTE--DLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKI-----SGEGRVRESITRTSRAPAVATVGSICDLNLKIPEINSSDMSAHVTSPSGHVTEAEI-VPMGKNSHC-VRFVPQEMGVHTVSVKYRGQHVTGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERGEAGIPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPDSPYLVPVIAPSDDARCLTVLSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGIHTIDVKFNG-SHVVGSPFKVRVGEPGQAGN--------------------------PALVSAYGAGLETGTTGIQSEFFINTTQAGPGTLSVTIEGPSKVKMDCQEI------PEGYKVMYTPMAPGNYLIGVKYGGPNH-ISRSPFKAKV 2471
BLAST of Filamin vs. UniProt/SwissProt
Match: sp|O75369|FLNB_HUMAN (Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2) HSP 1 Score: 1339.32 bits (3465), Expect = 0.000e+0 Identity = 860/2303 (37.34%), Postives = 1251/2303 (54.32%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP----YKESKIKAFGPGL--TGGIVSKPAFFEVETN--GETGALGFSIKGPSEA-KIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPST-----VKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS----VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQET--NNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEY-PETETPLLIS-ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSV------------VDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX---------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGST-----QKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 ++ +V A GPGLE GN P F + T AG G++ + V +P+G K E+ Y C Y P G + + I FA IP SPF V V A +P+ ASG G++P G + T F V T AG G + + KG ++ VK K + + EY G +S+ + + G I SPF V V + + ++ A G G+ G V A+F V + + LG + GP ++ + + C + Y P+ PG Y V I + I SP+ + P Y ++A+GPGL +G IV+ A F V+ G+ F+ G + I + DG+ +Y P ++ + ++ NIP SPY I + P KV +GPG+ SG+ N+P F V+ AG A + + I N + T++ +Y P G++T+ V + + IP SPF+V V + +A+ +K GPG+ +A + T+F V K AG + + + + ++D+ ++ DN D + T+KYTP G + + + IP+SPF V + + D K K+N L N +G+ EF + T G + + ++ + SP+ VP + A F P G + V V G+P+ SPY V A+ D K + P E L+ A++ ID K + + P E + ++ N + S ++ P + Y V E KA++ P V A G GL G +D +E P LG+ + +A++ +N DGT +V Y+P G Y + + Y E + P V + P D +++ +GPG+ VF+++ + FTV+++P+ G +KA I NP + C V +N DGTY Y+P G H +++TYD VP+ SP+ V V +G PSR++A GPGL+E T +P FTV GAG GGLG+++EGP++++I C DNKDG+CS +Y+P PG YDV+I + HIPGSPF VP+ D+VD SKVK GPGL +G R FTVD+SKAG APL+V V+ V+P ++ G VTY P G + V Y + ++P SPF VL + + KV +G G+ + + +P F I+ RDAGE L + +T + V ++ DGT+ Y D G Y + V YG ++P SP+ + +C GP I + V G+ V V+ + AG G ++ + P G + G + Y K G Y + + F +IPN A E ++E + +P + E V D P + V+ PS + P +++N DGT+TV+Y P+E GLHE+ + Y G I SP +FYV+ SG V+AYGPGL YG + A FTIVT+DAG GGL LA+EGPSKAEI CIDNK+GTC V+YLP PGDY I +K+ DKHI GSPFTAKI + ++ SQ+ +G+ +D L ISETD+++L A + +P+GR+E C LKRL N ++GISF P+EVGEHLV++ ++G H+ NSP I V ++EIG+A R K+YG GL++G E F+VDTR+AGYGG+SL++EGPSKV+I+ D DGTC V+Y PT PG YI++ K+AD +VPGSPF V I G + E I R A V+ +G++C+LNL IP N + +A V SPSG EI+ + N +RF+P+E+GVHTVSVK +HVTGSPFQFTVGPL +GG HKV G G+ERG A +F+I+TREAGAG LSIA+EGPSKAEI F D+K+GSCGV+Y EPG+Y SIKFNDEH+P SP+++ PV + +D+R +++ +LQ+ G + A+F I +G G I A V SPS + +S+++ ++Y+V F+P ENG+H + V N S + GSPF+V V V+ G G+ G TG +EFF++T+ AG G L+VTI+GPSKV+++CQE GY Y P APG+Y IS+KYGG NHI+GSPF ++G S S ET S L ++V S T K S V +G GL A +G+++ F+VD AG ++L +GV GP PCEEV++KH+GN ++ V Y V+E+G ++L V+WG +PGSPF + VP Sbjct: 353 DASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQVGEAC-NPNACRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQK--DFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPE---AGMQKVRAWGPGLH--GGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSC--DVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSH---PQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDII--DNYDYSHTVKYTPTQQGNMQVL-VTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEG--PCE-AKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAV-------DTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL-GSGVRARVLQSFTVDSSKAGLAPLEVRVLG-PRGLVEPVNVVDNGD-GTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYG---VPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATD-GEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYVNYP-NSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISG--EGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLV------------PVIAPS---DDARRLTVMSLQESGLKVNQPASFAIRLNG-AKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGDYVLAVKWGEEHIPGSPFHVTVP 2602 HSP 2 Score: 1066.22 bits (2756), Expect = 0.000e+0 Identity = 850/2604 (32.64%), Postives = 1244/2604 (47.77%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYK-ESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS------VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPI---GQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE--EGITKQPQKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFT--PSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE--YSVVDFKFPVGPVFDY-------VRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVD----STIPSGQVTAYGPGLSYGRP-----------DMHAH----FTIVTKDA-GAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVG---------TTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAV-----NIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDAN--QFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRX---XXXXXXXXXXXIHHGHTG-RINE--FFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWG--NHDVPGSPFEIVV 7621 + E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS +R H+RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGL+WTLILHYSI+MP+WE ++ D K +PKQRLLGWI +K+P+ P+ NF +W DG A+GALVD+CAPGLCP+W WDP++ + NA+EA+ A++ L V +I P E+I+P VDE ++MTYLSQFP A+L APL PK N + RAYG G+E GN + PA FTVDT +AG+G++ + V +P+G KE ++ +K YS Y+P + G +++ + FA I SPF+V+V A GD SKVTA GPG+E VGN + T+F+++TA AG G + + D +G K++V+ + + + Y + G H V +FFAG I SPF V V + N +A A+GRG+QP+GVR+R+ +F+V T+ AG +LGV + GP E + K +Y Y P PG Y + I +G + I SPF V V P K++A+GPGL GGIV + A F VE+ G E G+LGF+I+GPS+AKI+ D DGS +V YWP PGEYAVHI+CDDE+I SPYMA I T ++P V AYGPGL SG N A+F V+ K+AG + +K D GQ I +Q+++ DGTY+C YTP KHT+ V +G VNIP SP++VN+ + + +KV+GPG+ER+ K N T+F VDC AG GD+ + VL E DV N + TF YTI++ F+ EIP SPF+V ++ +D K K + G+ F + T G K + SP L +N +TPT G V V G+PI SP+ V ++ + E + ++ +D + + L+P R V P R N F P EE +Y V T + E P V A+G GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP +PG Y VN+L+ + HI SPF I D +KV A GPGL V + + G G + + ++ ++ NN DGTY+ +Y P G + + + Y G V P V V D SRI+ +GPG+E + + FTVD L G + I P+ A +CF DN DGT V+Y P + G + V + +++ IP SPF V + + S+V+ GPGL+ FT P+ FTV AG L + V + + + G YIP G+ ++ + Y +PGSPF V + +P KV + G G+ G + +V FT+++ AG + LE+ V GP ++V ++GDGT T Y G Y V V Y ++ +P SPF V V + GP L+ VP V ++ ++AG+G+L+ + G + + + G V+Y+P K G Y + + + ++IP R A Q T + SK + S V VG V D V V P + +I N DGT + Y ++ G + + V + G I SPF + + V A PG RP DM+ F +V A G ++ V PS A + +DNK+GT V Y P G + + IK+M HI SP + P S G T+ + + L+ + P+ E SC + +G +++ P G++ + V + +HIP SPF + ++ S+VKL F++D L+ SI+ PS + C +NH G +++ P E G +++++K ++V SP ++ IG + + R L E+S ++ GY + +V PS E L D + + P GV+ VS K + HV GSPF + G K I + +A + + E + +S + PS +AEI K+ C V + E G + S+K+ +HV GSPF + P + + + G A F I G +S V PS E + N V ++ E G + V + N+ IP SP+ V + + +G ++N+ F N G + + PS C +E Y ++P+ G +TI +K+ G +H++GSPF V + N P V G GL+ G ++EF ++ AG L V + GP + C+E ++V Y G +L+ V++G NH V GSPF+ V Sbjct: 3 VTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWE----DEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAKGPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQG-KNTVELLVEDKGNQVYRCVYKPMQPGPHVVKIFFAGDTIPKSPFVVQV-GEACNPNA--CRASGRGLQPKGVRIRETTDFKVDTKAAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFEVQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQNDGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGCIVNNLAEFTVDPKDAGK-APLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAVVWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVGIKCDARVLSEDEEDVDFDIIHNANDTF-TVKYVPPAAGRYTIKVLFASQEIPASPFRVKVDPSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAG-KAPLNVQFNSPLPGDAVKDLDIIDNYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGKDQEFTVDTRGAGGQG-KLDVTILSP-SRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTYDGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGPCEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADI-------EMPFDPSKVVASGPGLEHGKVGEAGLLSVDCSEA-----GPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQVGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKVAVTEGCQPSRVQAQGPGLK----EAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKIN----CRDNKDGSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGL----GSGVRARVLQSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADEEIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITDQEGKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQ--------------TGDASKCLATGPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGF---RPWVTEEAYVPVSDMNGLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHIKYMGSHIPESPLQFYV-NYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEGPSKAEISCIDNK--DGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDS-RRCSQVKL----------GSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIG---ISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDF----IVDTRDAGYG--GISLAVEGPSKVDIQTE--DLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKIS---GEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEI-VPMGKNSHC-VRFVPQEMGVHTVSVKYRGQHVTGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAE--ITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNG-SHVVGSPFKVRVGEPGQAGN--------------------------PALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQET------PEGYKVMYTPMAPGNYLISVKYGGPNHIV-GSPFKAKV 2471
BLAST of Filamin vs. UniProt/SwissProt
Match: sp|Q8BTM8|FLNA_MOUSE (Filamin-A OS=Mus musculus OX=10090 GN=Flna PE=1 SV=5) HSP 1 Score: 1156.35 bits (2990), Expect = 0.000e+0 Identity = 652/1520 (42.89%), Postives = 921/1520 (60.59%), Query Frame = 2 Query: 3212 NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE---------VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAF---QPQEQYSI--ERTTHHYTTEQ--------SKPIIR------TEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXX---------XXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETK-----SLTQTV----HMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 V G GL + A F +D + A L + I E + A++ D+GDGT ++ Y+P PG+Y V + Y + + + P + + P D + V YGPG+ GVF+++ ++F+V+A+ + G VKA + NP + V + DGTY Y+P +G H +D+TYDG PV SP+ VPV +G DPSR+R +GPG++ G T +P KFTV+ GAG GGLGL++EGP++A++ C DNKDG+CSV+Y+P + G+Y +++ + +PGSPF VP+HD+ D SKVKC GPGL R P F VD SKAG APL+V V V+P ++ + G V Y+P G+ I VLY +VP SPF VL + + KV +G G+ + +P FTI+ +DAGE L + +T P + + ++ DGT+T Y DVPG YT+ + YG +P SP+ V +C + I + +G+ I V+T+ AG G ++ P G+ V + G + Y + G Y + + F E++PN + A QP Q + ++ Y Q +P++ T D P + V PS + P + +N DGT+TV+Y PSE+GLHE+++ Y+ I GSP +FYVD + G +TAYGPGL++G + A FT+ TKDAG GGLSLA+EGPSKAEI C DN++GTC VSYLP+ PGDY I +K+ D+HI GSPFTA++ G+ R S + VG+ +D+P+ ISETD++ L A V+ P+GREE C LKRL+NG++GISF PKE GEHLV+V ++G+H+ +SP + + ++EIG+ASRV++ G GL++G E +F++DTR+AGYGGLSLSIEGPSKV+I D DGTC VTY PTEPG YIIN+K+AD +VPGSPF+V + G + E I R + A V+ IG+ C+L+L IP + ++ TA V SPSG EI+ ++ + IRF+P E+G+HTVSVK +HV GSPFQFTVGPL +GG HKV G G+ER +F I+TREAGAG L+IA+EGPSKAEI F+D KDGSCGV Y V EPGDY S+KFN+EH+P SPF++ P +S S D+R +++++LQ+ G + A+F ++ +G G+I A V SPS + +++ID ++Y+V F+P ENGI+ + V N + IPGSPF++ VGE V+ G G+ G TG EF V+TSNAG GAL+VTIDGPSKV+++CQE GY TY P APG Y ISIKYGG HI GSPF ++G SN S+ ET SLT+ H SG GP+ V +G GL A +G+++ F VD AG ++L VGV GP PCEE+ +KH+G+ + V+Y +++KG + L+V+WG+ +PGSP+ I+VP Sbjct: 1162 KVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAV-------DTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQDCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKV-QGPKGLVEPVDVVDNAD-GTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTG---VPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVD-YVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTG--EGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVV-----PVASPS----------GDARRLTVSSLQESGLKVNQPASFAVSLNG-AKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGP---GPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMVP 2647 HSP 2 Score: 1047.73 bits (2708), Expect = 0.000e+0 Identity = 823/2610 (31.53%), Postives = 1244/2610 (47.66%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTH-KRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP-YKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNT-TPIGQLNEFEILTPFDGS---KVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETET--PLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNEK-------------AELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP-QKFTVDLEGAGQGG---LGLSIEGPA----DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----------GEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTH---HYTTEQSKPIIRT-EYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKF--------YVDSTIPSGQ---------------------VTAYGPGLSYGRP-DMHAHFTIVTKDAGAGGLSLAVEGPSK--AEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF--------TAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIEC--HDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCE-LNLII----PGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQ--FTIYTREAGAGSLSIAIEGPSKA--EIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTG----RINE--FFVDTSNAGNGALTVTIDGPSKVQLNC---QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK + I +LQ DL+DGL+LI L++ LS H +RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W+ E+ + Q +PKQRLLGWI +K+P P+ NF+ DW G A+GALVD+CAPGLCP+W WD + + NA+EA+ A++ L + +I P E+++P VDE ++MTYLSQFP A+L APL PK N + RAYGPG+E GN + A FTV+T +AG+G + + V +P G +E ++ + +K +S Y+P + G +++ + FA I SPF+V V + GD SKVTA GPG+EP GN + T+F +FTA AG G V+ VI D G+K +V+P++ + ++ + Y EG+H+V+V FAGV I SP+ V V + + + A GRG+QP+GVRV++ A+F+V+T+ AG +L V V GP + E+ + K + +Y Y P PG Y V I +G I SPF V V K++A+GPGL GGIV K A F VE G + G LGFS++GPS+AKI+C D GDGS +V YWP GEYAVH+LC+ E+I SP+MA I+ + F P +V A GPGL +G++ NKPA+F V+ K+AG + ++ + D G ++ ++DN +GTYSC Y P+ P KHT +VS+G V+IP SPF+VNV + +KVYGPG+ + K + TYF VDC AG GD+ I + E D ++ +DN T +YTI + F++ P SP +V +E +D K K LN T +G+ F + G V+ + K V + + +N + + P GP V V G+ I SP+ V + ++ + + + + D K+ ++K+ + V P N F P EE Y V+ T + A + V A+G GL G A +PA F ID+ LG+T+EGP EA+++ +DNGDGTCSV+Y+P EPG Y +N+L+ D HI SPF + P D +KV GPGL +F V+ G + I + + + ++ DGT++ +Y P G + + I Y G PV P + V D S ++ YGPG+E +G+ ++ +F+VD Q G + + P+ D +Q D DGT V+Y P + G + V + ++ +P SPF VP+ + D S+V+ +GPG++ + P++FTV+ A G + K++ +D G V YIP G + V Y QVPGSPF V + + KV +G G+ P G + AN +P F ++T AG + L++ V GP +DV ++ DGT T Y G+Y++ VLYG + VP SPF V V + GP LN VP V ++ ++AG+G+L+ + P G I++ G TV+YVP G Y + + + + IP R A + T H P I+ E +V+ V + DV ++ N DGT + Y + G + + V + G+ + SPF+ V + + S Q V G ++ RP D+ FTI G ++ V PS A+ DNK+GT V Y P G + + I++ + HI GSP I + V + + + L+ + P+ E SCT Q+G +S+ P G++ + V + +HIP SPF V ++ S +K V ++ L+ ++ PS E C +G +++ P E G ++++VK +V SP V I S S R + + + G+ E II GY + S+ PS E L D + + P E G + +++K ++HV GSPF V G K I +AN + ++ E ++ + PS E + + ++ + + + E G + S+K+ +HVPGSPF + P + + + +G A F I G ++ V PS E S + V +V E G + V V N IP SPF V V + + ++N+ F + N GA+ + PS C + ++ Y ++P G Y I +K+ G HI GSPF + + + + P V G GL+ G EFIV+ AG L V + GP + C+E ++V Y G +L+ +++G + + GSPF+ V Sbjct: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQ----TPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGMGEVEVVIQDPTGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPAACR---AIGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGP-KGEERVKQKDLGDGVYGFEYYPTIPGTYTVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGIVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIREAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHAGK-APLRVQVQDNEGCSVEATVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPTEADIDFDIIRNDNDTFTV---KYTPCGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLNRTGVELGKPTHFTVNAKTAGKGKLDVQFSGLAKGDAVRDVDI-IDHHDNTYTVKYIPVQQGPVGVNVTYGGDHIPKSPFSVGVSPSLDLSKIKVSGLGDKVDVGKDQEFTVKSKGAGGQGKVASKIVSPSGAAVPCKVEPGLGADNSVVRFVPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGNAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVAP-------CFDASKVKCSGPGLE--RATAGEVGQFQVDCSSA---GSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTDTYVQ--DCGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTN--KPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKD--------------GSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSP--GMVRAN-LPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGSYSISVLYGEEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVPGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDV-DVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPTVQTPLRSQQLAPQYNYPQGSQQTWIPERPMVGVNGLDVTSLRPFDLVIPFTI-----KKGEITGEVRMPSGKVAQPSITDNKDGTVTVRYSPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHITAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDN--QDGTCSVSYLPVLPGDYSILVKYNDQHIPGSPFTARVTGDDSMRMSHLK----------VGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVI----SQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYG--GLSLSIEGPSKVDINTE--DLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKV---TGEGRVKESITRRRRAPSVANIGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGMHTVSVKYKGQHVPGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERAEVGVPAEFGIWTREAGAGGLAIAVEGPSKAE--ISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGIYLIDVKFNG-THIPGSPFKIRVGEPGHGGD--------------------------PGLVSAYGAGLEGGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMDCQEC------PEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2516 HSP 3 Score: 92.0485 bits (227), Expect = 9.151e-17 Identity = 88/318 (27.67%), Postives = 134/318 (42.14%), Query Frame = 2 Query: 965 LELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA--GDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAG-VQIQSSPF-------------------GVMVSSKTSNSDAKQAYATG-----------RGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV 1816 L+ G + PA F V + N KG +D V +P G E C + + + Y+ +IP G Y I +KF + IP SPFK+ V GDP V+A G G+E G G F V T+ AG G++ I +K + D ++ + + YT G + +++ + G I SPF V V S T + Q +G +G+ V + F V AG L V V+GP E+ +K + LY SY+ + G Y + +K+G+ I SP+ + V Sbjct: 2340 LQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDK--YAVRFIPRENGIYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLE--GGVTGSPAEFIVNTSNAGAGALSVTIDGPSKVKMD------CQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKVATVPQHATSGPGPADVSKVVAKGLGLSKAYVGQKSNFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHMGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRIMV 2646
BLAST of Filamin vs. UniProt/SwissProt
Match: sp|P21333|FLNA_HUMAN (Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4) HSP 1 Score: 1154.04 bits (2984), Expect = 0.000e+0 Identity = 646/1517 (42.58%), Postives = 919/1517 (60.58%), Query Frame = 2 Query: 3212 NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE---------VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAF---QPQEQYSI--ERTTHHYTTEQ--------SKPIIR------TEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXX---------XXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSL------TQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 V G GL + A F +D + A L + I E + A++ D+GDGT ++ Y+P PG+Y V + Y + + + P + + P D + V YGPG+ GVF+++ ++F+V+A+ + G VKA + NP + V + DG Y Y+P +G H +D+TYDG PV SP+ VPV +G DPSR+R +GPG++ G T +P KFTV+ GAG GGLGL++EGP++A++ C DNKDG+CSV+Y+P + G+Y +++ + +PGSPF VP+HD+ D SKVKC GPGL R P F VD SKAG APL+V V V+P ++ + G V Y+P G I VLY + +VP SPF VL + + KV +G G+ + +P FTI+ +DAGE L + +T P + + ++ DGT+T Y DV G YT+ + YG +P SP+ V +C + I + +G+ I V+T+ AG G ++ P G+ V + G + Y + G Y + + F E++PN + A QP Q + ++ YT Q +P++ T D P + V PS + P + +N DGT+TV+Y PSE+GLHE+++ Y+ I GSP +FYVD + G VTAYGPGL++G + A FT+ TKDAG GGLSLA+EGPSKAEI C DN++GTC VSYLP+ PGDY I +K+ ++H+ GSPFTA++ G+ R S + VG+ +D+P+ ISETD++ L A V+ P+GREE C LKRL+NG++GISF PKE GEHLV+V ++G+H+ +SP + + ++EIG+ASRV++ G GL++G E +F++DTR+AGYGGLSLSIEGPSKV+I D DGTC VTY PTEPG YIIN+K+AD +VPGSPF+V + G + E I R + A V+ +G+ C+L+L IP + ++ TA V SPSG EI+ ++ + IRF+P E+G HTVSVK +HV GSPFQFTVGPL +GG HKV G G+ER A +F+I+TREAGAG L+IA+EGPSKAEI F+D KDGSCGV Y V EPGDY S+KFN+EH+P SPF++ P +S S D+R +++++LQ+ G + A+F ++ +G G+I A V SPS + +++ID ++Y+V F+P ENG++ + V N + IPGSPF++ VGE V+ G G+ G TG EF V+TSNAG GAL+VTIDGPSKV+++CQE GY TY P APG Y ISIKYGG HI GSPF ++G SN S+ ET S+ T G+ GP+ V +G GL A +G+++ F VD AG ++L VGV GP PCEE+ +KH+G+ + V+Y +++KG + L+V+WG+ +PGSP+ +VVP Sbjct: 1162 KVKCSGPGLERATAGEVGQFQVDCSSAGSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAV-------DTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTNKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKDGSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSPGMVRANLPQSFQVDTSKAGVAPLQVKV-QGPKGLVEPVDVVDNAD-GTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTG---VPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTIKKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVD-YVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDNQDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLKVGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVISQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTG--EGRVKESITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVV-----PVASPS----------GDARRLTVSSLQESGLKVNQPASFAVSLNG-AKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVVP 2647 HSP 2 Score: 1050.04 bits (2714), Expect = 0.000e+0 Identity = 816/2608 (31.29%), Postives = 1239/2608 (47.51%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTH-KRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVA-PYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNT-TPIGQLNEFEILTPFDGS---KVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETET--PLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN----FEPNEEIIYPVQRTNEK-------------AELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP-QKFTVDLEGAGQGG---LGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKA----------GEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTH---HYTTEQSKPIIRT-EYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYV-----DSTIPSGQVTAYGPGLSYG----------RP---------------DMHAHFTIVTKDAGAGGLSLAVEGPSK--AEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF--------TAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIEC--HDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCE-LNLII----PGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQ--FTIYTREAGAGSLSIAIEGPSKA--EIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGHTG----RINE--FFVDTSNAGNGALTVTIDGPSKVQLNC---QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK + I +LQ DL+DGL+LI L++ LS H +RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W+ E+ + Q +PKQRLLGWI +K+P P+ NF+ DW G A+GALVD+CAPGLCP+W WD + + NA+EA+ A++ L + +I P E+++P VDE ++MTYLSQFP A+L APL PK N + RAYGPG+E GN + A FTV+T +AG+G + + V +P G +E ++ + +K +S Y+P + G +++ + FA I SPF+V V + GD SKVTA GPG+EP GN + T+F +FTA AG G V+ VI D G+K +V+P++ + ++ + Y EG+H+V+V FAGV I SP+ V V + S + A GRG+QP+GVRV++ A+F+V+T+ AG +L V V GP + E+ + K + +Y Y P PG Y+V I +G I SPF V V K++A+GPGL GG+V K A F VE G + G LGFS++GPS+AKI+C D GDGS +V YWP GEYAVH+LC+ E+I SP+MA I+ + F P +V A GPGL +G++ NKPA+F V+ K+ G + ++ + D G + ++DN +GTYSC Y P+ P KHT +VS+G V+IP SPF+VNV + +KVYGPG+ + K + TYF VDC AG GD+ I + E D ++ +DN T +YTI + F++ P SP +V +E +D K K L+ T +G+ F + G V+ + K V + + +N + +TP GP V V G+PI SP+ V + ++ + + + + D K+ ++K+ + V P N F P EE Y V+ T + A + V A+G GL G A +PA F ID+ LG+T+EGP EA+++ +DNGDGTCSV+Y+P EPG Y +N+L+ D HI SPF + P D +KV GPGL +F V+ G + I + + + ++ DGT++ +Y P G + + I Y G PV P + V D S ++ YGPG+E +G+ ++ +F+VD Q G + + P+ + + D DG V+Y P + G + V + ++ +P SPF VP+ + D S+V+ +GPG++ + P++FTV+ A G + K++ +D G V YIP G + V Y QVPGSPF V + + KV +G G+ P G + AN +P F ++T AG + L++ V GP +DV ++ DGT T Y G Y++ VLYG++ VP SPF V V + GP LN VP V ++ ++AG+G+L+ + P G I++ G TV+YVP G Y + + + + IP R A + T H P I+ E +V+ V + DV ++ N DGT + Y + G + + V + G+ + SPF+ S P + P +Y RP D+ FTI G ++ V PS A+ DNK+GT V Y P G + + I++ + HI GSP + + V + + + L+ + P+ E SCT Q+G +S+ P G++ + V + +H+P SPF V ++ S +K V ++ L+ ++ PS E C +G +++ P E G ++++VK +V SP V I S S R + + + G+ E II GY + S+ PS E L D + + P E G + +++K ++HV GSPF V G K I +AN + ++ E ++ + PS E + + ++ + + + E G + S+K+ +HVPGSPF + P + + + G A F I G ++ V PS E S + V +V E G + V V N IP SPF V V + + ++N+ F + N GA+ + PS C + ++ Y ++P G Y I +K+ G HI GSPF + + + + P V G GL+ G EF+V+ AG L V + GP + C+E ++V Y G +L+ +++G + + GSPF+ V Sbjct: 32 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDR-ESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEEAKKQ----TPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQACNPSACR---AVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGP-KGEERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKVGTECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGK-APLRVQVQDNEGCPVEALVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRNDNDTFTV---KYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGLTKGDAVRDVDI-IDHHDNTYTVKYTPVQQGPVGVNVTYGGDPIPKSPFSVAVSPSLDLSKIKVSGLGEKVDVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVEPGLGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPTKPSKVKAFGPGLQGGSAGSPARFTIDTKGAGTGGLGLTVEGPCEAQLECLDNGDGTCSVSYVPTEPGDYNINILFADTHIPGSPFKAHVVP-------CFDASKVKCSGPGLE--RATAGEVGQFQVDCSSA---GSAELTIEICSEAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSGVQCYGPGIEGQGVFREATTEFSVDARALTQTGGPHVKARVANPSGNLTETYVQDRGDGMYKVEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGCDPSRVRVHGPGIQSGTTN--KPNKFTVETRGAGTGGLGLAVEGPSEAKMSCMDNKD--------------GSCSVEYIPYEAGTYSLNVTYGGHQVPGSPFKVPVHDVTDASKVKCSGPGLSP--GMVRAN-LPQSFQVDTSKAGVAPLQVKVQGPKGLVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKASGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTHIQDNHDGTYTVAYVPDVTGRYTILIKYGGDEIPFSPYRVRAVPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEETVITVDTKAAGKGKVTCTVCTPDGSEVDV-DVVENEDGTFDIFYTAPQPGKYVICVRFGGEHVPNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTI-----KKGEITGEVRMPSGKVAQPTITDNKDGTVTVRYAPSEAGLHEMDIRYDNMHIPGSPLQFYVDYVNCGHVTAYGPGLTHGVVNKPATFTVNTKDAGEGGLSLAIEGPSKAEISCTDN--QDGTCSVSYLPVLPGDYSILVKYNEQHVPGSPFTARVTGDDSMRMSHLK----------VGSAADIPINISETDLSLLTATVVPPSGREEPCLLKRLRNGHVGISFVPKETGEHLVHVKKNGQHVASSPIPVVI----SQSEIGDASRVRVSGQGLHEGHTFEPAEFIIDTRDAGYG--GLSLSIEGPSKVDINTE--DLEDGTCRVTYCPTEPGNYIINIKFADQHVPGSPFSVKV---TGEGRVKESITRRRRAPSVANVGSHCDLSLKIPEISIQDMTAQVTSPSGKTHEAEIVEGENHTYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTV--GPLGE------------GGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLAIAVEGPSKAE--ISFEDRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSGDARRLTVSSLQESGLKVNQPASFAVSLNGAKGAIDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNG-THIPGSPFKIRVGEPGHGGD--------------------------PGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQEC------PEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKV 2516 HSP 3 Score: 177.948 bits (450), Expect = 6.732e-43 Identity = 208/837 (24.85%), Postives = 345/837 (41.22%), Query Frame = 2 Query: 5276 QVTAYGPGL--SYGRPDMHAHFTIVTKDAGAGGLSLAVEGPS----KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICV------------GTTSDVPLRISETDINNLNAIVISPTGREESC--TLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDG--MVNETCQFVVDTRNAGYGGLSLSIEGPSKVE-IECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPL-IDGGPHKVHIMGSGVER-GLA-NDANQFTIYTREAGAGSLSIAIEGPSKAEID--FQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDE----NPYSSYSKPVKNENIIFNDSRYISI-AALQDQG-FNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG--------HTGRINEFFVDTSNAGNGALTVTIDGPSKVQLN-----CQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGD----VLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPF--EIVVPN 7627 + AYGPG+ + A FT+ T+ AG G + + VE P+ +A++ ++KN T V Y+P G + + + F +HI SPF + S++ T+ + + + ++ P G++ + L+ + S+ P G H V+V +G IP SP+ + VG+ N S + G GL V ET F V T+ AG G L ++++GP E ++ D DG Y P PGTYI+ + + N+ SPF V +G + +++ E +G + + G + SV PS + C+ D +R+ P+E G + V V ++ + SPF + D P +V G G+E+ G+A N +FT+ + G L + ++ ++ +DN +G+ +Y +P + + + +P SPF + + N Y V + ++ Y ++ A QG +IG K + V+ P+ + I + DN+ ++V + P G + + VL + P SP RV V + + G G+ F V+ AG G L V G +K +++ Y Y P G +++ YGG+ I SPF VA+S S+ +K +K G G KV ++GK EF V + AGG VG SG PC+ LG + V + +E+G + + V + VPGSPF E V P Sbjct: 283 KARAYGPGIEPTGNMVKKRAEFTVETRSAGQGEVLVYVEDPAGHQEEAKVTANNDKNRTFSVWYVPEVTGTHKVTVLFAGQHIAKSPFEVYVDKSQGDASKVTAQGPGLEPSGNIANKTTYFEIFTAGAGTGEVEVVIQDPMGQKGTVEPQLEARGDSTYRCSYQPTMEGVHTVHVTFAGVPIPRSPYTVTVGQ--ACNPSACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVTVKGPKGEERVKQKDLGDGVYGFEYYPMVPGTYIVTITWGGQNIGRSPFEVKVG---TECGNQKVRAWGPGLEGGVVGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECD--DKGDGSCDVRYWPQEAGEYAVHVLCNSEDIRLSPFMADIRDAPQDFHPDRVKARGPGLEKTGVAVNKPAEFTVDAKHGGKAPLRVQVQDNEGCPVEALVKDNGNGTYSCSYVPRKPVKHTAMVSWGGVSIPNSPFRVNVGAGSHPNKVKVYGPGVAKTGLKAHEPTYFTVDCAEAGQGDVSIGIKC--------------APGVVGPAEADIDFDIIRNDNDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRVKVEPSHDASKVKAEGPGLSRTGVELGKPTHFTVNAKAAGKGKLDVQFSGLTKGDAVRDVDIIDHHDNTYTVKYTPVQQGPVGVNVTYGGDP-IPKSPFSVAVS-------PSLDLSK----------------------IKVSGLGEKV-DVGKDQEFTVKSKGAGGQGKVASKIVGPSGAAVPCKVE--PGLGADNSVVRFLPREEGPYEVEVTYDGVPVPGSPFPLEAVAPT 1065 HSP 4 Score: 149.058 bits (375), Expect = 3.966e-34 Identity = 138/493 (27.99%), Postives = 218/493 (44.22%), Query Frame = 2 Query: 1037 NLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKN-AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESK----IKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHI-LCDDENIPKSPYMAQI------------QLDTKLFDPL--------------------KVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQ---IRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV 2389 ++ V +P G+ EI + N Y ++P G + + +K+ +P SPF+ V G KV A GPG+E E G F+++T EAG G + + + S + + + + Y +E G + V+V F I SPF V V+S + DA++ T +Q G++V A F V A A + V+ P +LE+C + ++ Y +IP+ G Y++D+K+ I SPF + V + A+G GL GG+ PA F V T N GAL +I GPS+ K+DC + +G VTY P PG Y + I +I SP+ A++ + + D L KV A G GL S + + F V+ AG+ + V G P + ++ YS Y K G++T++V +G+ +IP SP++V V Sbjct: 2173 DMTAQVTSPSGKTHEAEIVEGENH--TYCIRFVPAEMGTHTVSVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERA--EAGVPAEFSIWTREAGAGGLAIAVEGPSKAEISFE----DRKDGSCGVAYVVQEPGDYEVSVKFNEEHIPDSPFVVPVASPSG--DARRL--TVSSLQESGLKVNQPASFAVSLNGAKGA-IDAKVHSPSGALEECYVTEIDQDKYAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLEGGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQECPEGY-RVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGL-SKAYVGQKSSFTVDCSKAGNNMLL----VGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVV 2646 HSP 5 Score: 95.5153 bits (236), Expect = 7.556e-18 Identity = 92/318 (28.93%), Postives = 135/318 (42.45%), Query Frame = 2 Query: 965 LELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA--GDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILD-TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAG-VQIQSSPF-------------------GVMVSSKTSNSDAKQAYATG-----------RGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV 1816 L+ G + PA F V + N KG +D V +P G E C + + + Y+ +IP G Y I +KF + IP SPFK+ V GDP V+A G G+E G G F V T+ AG G++ I +K + D ++ + + YT G + +++ + G I SPF V V S T + A Q A G +G+ V + F V AG L V V+GP E+ +K V LY SY+ + G Y + +K+G+ I SP+ V V Sbjct: 2340 LQESGLKVNQPASFAV-SLNGAKGAIDAKVHSPSGALEECYVTEIDQDK--YAVRFIPRENGVYLIDVKFNGTHIPGSPFKIRVGEPGHGGDPGLVSAYGAGLE--GGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMD------CQECPEGYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKAYVGQKSSFTVDCSKAGNNMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVV 2646 HSP 6 Score: 63.1586 bits (152), Expect = 4.395e-8 Identity = 62/227 (27.31%), Postives = 94/227 (41.41%), Query Frame = 2 Query: 944 VRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANS-EIPNSPFKVNVKN----------------------------------AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENK-FLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMV 1516 V AYG GLE G GNPA F V+T NAG G L + + P K C+ + P Y +Y P G Y I IK+ I SPFK V D SKV A G G+ VG+++ F V ++AG + +++ G + + + K ++ + + Y K++G +++ V + I SP+ V+V Sbjct: 2432 VSAYGAGLE--GGVTGNPAEFVVNTSNAGAGALSVTIDGPSKVKMDCQ--ECPE---GYRVTYTPMAPGSYLISIKYGGPYHIGGSPFKAKVTGPRLVSNHSLHETSSVFVDSLTKATCAPQHGAPGPGPADASKVVAKGLGLSKA--YVGQKSSFTVDCSKAGN---NMLLVGVHGPRTPCEEILVKHVGSRLYSVSYLLKDKGEYTLVVKWGDEHIPGSPYRVVV 2646
BLAST of Filamin vs. UniProt/SwissProt
Match: sp|Q9VEN1|FLNA_DROME (Filamin-A OS=Drosophila melanogaster OX=7227 GN=cher PE=1 SV=2) HSP 1 Score: 1132.86 bits (2929), Expect = 0.000e+0 Identity = 726/2005 (36.21%), Postives = 1080/2005 (53.87%), Query Frame = 2 Query: 1832 SKIKAFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKGPS----EAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGS--PSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNG-FVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPE---TETPLLIS--------ADYAID-NKAYNKP-SIPVQSAKLT--PVERSNVKTFSNPN-KQRSNFEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVA-NTPASFIIDSTEEPPAPLGVTI---EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFN-GKGIVKAIITNPFNQ-RSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNC-EIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTE---------YSVVDF-KFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDV--PLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG-------HTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMIS-GSTQKGPSKPY------NVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 ++++A+GPG+ G +V PA F VET + G++ I+GP+ +A + ++ + + V+Y P G + V + +IPKSP+ ++++ D KV GPG+ +G++ KP F + K+AG P + + + ++ ++R + T+ C Y + G H+V V Y IP SPF V V +A ++ G G++ + + F + + AG G+ + V+ + V+ DG + T Y I + F+ E+ +SPF+V + + ++ IG F + T +G V P S+ ++ + +G + + PT +G + V + C I SP+ IA T +PE P L + +D +KA N P + VQ T PVE N NP+ ++ + P + + V+ R + V A+G L GV N F +D+ E A L V I E +E IDN D T SV +P G+Y + Y + + P + + DV+K+ GL P+ V ++ + F V+ + N G + I +P + V D + Y+P G+H I++ YD +PV SP+ V V G DP+R +AYGPGLE+G+T Q KFTV+ +GAG GGL L+IEGP++A++ C DN+DG+C V YL PG YD++I+F +KHIPGSPF V + + VD SKVK YGPG+E R P+ F VD +AG + V + ++ V ++ K ++ V Y+P G+ +V ++ ++VP SPFV V EP KV V G + +P+ F I+T+ AG++D+ + + P +++ ++ GT+ + D G Y + YG+K + GSPF + + ++C + G + V+ + AGDG ++ K G+ + E+ G + Y G Y++ + F ++IPNGS A + EQYS +TT+ + ++E Y V F K P+ V A V PS + D P + +N DGT++V+Y P E G HEL V YNG+P+ GSPFKF+VDS I SG VTAYGPGL++G A+FTI TK A AGGL++AVEGPSKA+I DNK+GT V YLP APG+Y + ++F DKHI GSP+ AKI GE +KR+QI VG+ S+V P I++ D+ LNA + +P+G EE C LKR+ G +GISFTP+E+GEHLV+V R G+HI NSPFK+ V E E+G+A +VK+ G GL +G + F VDTRNAG+GGLS+SIEGPSK EI+C D DGT ++YKPTEPG YI+N+K+AD +V GSPF V + G S+ E+I R +DA +++IG+ C+L +PG + A V SPS E EI + D +++ F+PKELGVHTVSV+ H+ GSPFQFTVGPL D G H V GSG+ERG+ +A +F ++TREAG GSL+I++EGPSKA+I+F+D KDGSC V+Y+V EPG+Y +KFND H+P SPF + + + D+ + + + F++ +G G + A +++PS + I ID YSV F P ENGIH +HV N IP SPFR+ VG+ +H TG +F ++T NAG G L V+IDGPSKV ++C E E GY Y P PG++ I++KY N HI+GSPF V +G+ + + + +TV ++ G G P V +G GLK A IGK+N+F + A AG ++LYVG+ GP PCEE ++KH G+N + V Y V+++G+++L+++WG +PGSPF+I V Sbjct: 255 NRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPF--PVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPAN-HKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVM-QSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVET--NGETGALGFTVAGP--SQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF--IAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKN-----NPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRV---PLGEKVVVEQTV-----DVSKIKV--DGLEPS-VIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGN-CIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKK----TPASLPAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVDS-ITSGYVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPSKADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKRNQISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPSKADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA---------------GDAHKLEVQQFPQGNIQADAPYQFMVRKNG-AKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVGKDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKY-NNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV 2210 HSP 2 Score: 1007.67 bits (2604), Expect = 0.000e+0 Identity = 740/2289 (32.33%), Postives = 1145/2289 (50.02%), Query Frame = 2 Query: 173 AERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAG-SPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIE-RAKTNIETYFVVDCKLAGSGDIGISVLDEKMR-DVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKV---RPEIIVKSPNGSRVPVKLQE--TNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV---IATDRVNTKEY-PETETPLLISAD-YAIDNKAYNKPSIPV-----QSAKLT-----------------PVERSNVKTFSNPNKQRSNFEP-NEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVA--NTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYI---DNGDGTCSVNYLPKEPGSYIV-NVLYNDEHIKDSPFNVTIYPDTKSS----SNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFD--NKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFT----------PSQFTVDASKAGEAPLKVNVIDTATKSVKPAQ-----ILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKT--VTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQ----EQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYV---DSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSK----AEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFT-------------AKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNH-DGTCL-VTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQF---------------------TVGPLIDGGPH-------------KVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDG--SCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQI 6655 AER+LAEDAQWK IQ+NTFTRWAN+HLK + I++L+ DL+DGL+LI L++ LS +KRP FR+QKLENV++ L+FL++ EG+++VNIDSSDI DC+LKLILGLIWTLILHYSI+MP+W+GED Q +G G +PKQRLL WI++K+P P+ NFT DW G A+GALVDACAPGLCP+W WDPK A++NA EA+ A++ LNV LI+P E++NP VDE++MMTYLSQ+PN++L APL PKTN RVRAYGPG+E G +G PA FTV+TF+AGKG++D+ + P G+ E ++ + +K L Y+ SYIP EG +++ +KF+ +IP SPF V V+ AGD SKV +GPGI+P G + + TFF++ +AG G + +I+D K SV K+ + + + EY T +GLHSVNVF+AG I +SPF V V+ SDA++ A+GRG+Q GVRV D A+F+++TE AG + V V GPG + KV YEC Y P + G YV+ + + + SPF V V P KES I A+GPGL+ G++ PA F VETNGETGALGF++ GPS+A+I+C DNGDGSA V Y PT GEYAVHILCD+E+IPKSP++AQI L F P V A GPGL +G++ N+P F V+ AG +P V + DV G +PV++++N DGT YTP HTV V+YG V+ P SP +V V +AA ++ +GP ++ + N T+F VD + AG ++ + ++ E+ + +VP DN D T++++ P + G T + + +P KV +E D K K++ L + + +F + GS + + + P G +P K+ + T++ F +TP G HT+ + P+ SP+ V D K Y P E L + + ++ K + + AK+T P E F++ + S F EE + P + V YG G+ G + P F +D E P + V + +D + D G+ +V+Y+P + GS + V +++ + SPF +T++P ++ + +++ K A P ++F ++ K G+ + I NP + ++ GTY S+ P G ++ I Y + SP+ + + + + + + + VD AG G + I A ++I D KDG + Y PG YD+++KF K IP F++ + ++ Y +E + ++V S+ T + + PL + + P+ ++ + G V Y P G+ E+ V YN V GSPF +V +S V G G+ H + + P+ FTI+T+ A L + V GP+ +N DN DGT + QY PG Y V V +G+K++ GSP+ + E + N++ VG VT+P + + L+A P G PC ++ G+ +S+ P++IG + V + ++I N + + + ++ + T + I + F + +A + C + DGT+ + Y+P+E G + + + + + GSPF V S ++ + T + L+ V PS AEIQ ++ +G V ++P G + + +++ + HI GSPF K G +R VG ++ + E +L V P+ + K ++G +S+ E GE+ V + + RHIP+SPFK++V + G+A ++++ + + QF+V +N G L I PS + +C DG V + P E G + I+VK+ ++P SPF + +G + + H + ++ + + II N T +V S G ++ + + +R+ P G H ++VK +N H+ GSPF+ TV + GG + KV G G+++ NQF+I +AG L + + GP +F G + V Y V + G YV IK+ +EH+PGSPF + + Sbjct: 3 AERDLAEDAQWKKIQQNTFTRWANEHLKTIDRSINNLETDLSDGLRLIALIEVLSQKRMPKYNKRPTFRSQKLENVSVALKFLQD-EGIKIVNIDSSDIVDCKLKLILGLIWTLILHYSISMPMWDGEDDKQLNGSGH--TPKQRLLNWIHAKIPDLPINNFTNDWTTGKAVGALVDACAPGLCPDWELWDPKDAVQNASEAMGLADDWLNVRQLIKPEELVNPNVDEQSMMTYLSQYPNSKLKTGAPLRPKTNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVDIQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNGVTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPL---SDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTYECHYYPTKEGRYVIMVTFAGQEVAKSPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGPSQAEIECHDNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPFIAQI-LPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQ--DVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYVGVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQ-RVPLGE-KVVVEQTVDVSKIKVDGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKIVQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNVKSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTCTDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVDPSK------------VKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTVFPKSEPTKVKVKGVNEKKKTPASLP------------AEFEIDTKQA---GQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEY---IEEHTTKVVQQTTQSELVNGKSEITYRSVAFEKLPLPTTGGNVTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHV-DSITSGYVTAYGPGLT----HGVTGE-PANFTISTKGASAGGLTMAVEGPSKADINYH-DNK-DGTVSVQYLPTAPGEYQVSVRFGDKHIKGSPYFAKITGEGRKR---------NQISVGSCSEVTMPGDITDDDLRALNASIQAPSGLEEPCFLKRMPTGNIGISFTPREIGEHLVSVKRLGKHINNSPFKVTVCEREVGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPSKAEIQC----------TDKDDGTLNISYKPTEPGYYIVNLKFADHHVEGSPFTVKVAGEGSNRKREKIQRERDAVPITEIGSQCKLTFKMPGITSFDLAACVTSPSNVTEDAEIQEVE--DGLYAVHFVPKELGVHTVSVRYSEMHIPGSPFQFTVGPLRDSGSHLVKAGGSGLERG--VVGEAAEFNVWTREAGGGSLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPDSPFKVYVSPDA-GDAHKLEVQQFPQGNIQADAPYQFMV-RKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVHIPDSPFRIKVG----KDVADPAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAV-SIDGPSKVAMDCTEVEEGYKVRYTPLLPGEHYITVKYNNMHIVGSPFKVNATGDKLADEGAQETSTVIVETVQKVAKGGKNTGVHLPTFKSDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEHIPGSPFQIDV 2210 HSP 3 Score: 228.024 bits (580), Expect = 4.566e-58 Identity = 304/1254 (24.24%), Postives = 530/1254 (42.26%), Query Frame = 2 Query: 4064 PIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGL-FDVTYIPENIGNCEIEVLYNNMQVPGSPF-VQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNE--SVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVH--SEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVG---NIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIER----TTHHYTTEQSKPIIRTEYSVVDFKFPV-GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQ-----VTAYGPGLSYGRPDMH--AHFTIVTKDAGAGGLSLAVEG--PSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQI-CVGTTSDVPLRISETDINNLNA-----------IVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMV-NETCQFVVDTRNAG----YGGLSLSIEG------PSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDA--NQFTIYTREAGAGSLSIAIEGPSKAEID-FQDNKDGSC--GVTYRVNEPGDYV-CSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX--XXXXXXXXXIHHG----HTGRINEFFVDTSNAGNGALTVTID---GPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAI-SGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGL--AGGDVLYVGVSGPVR-PCEEVNIKHLGNNR---FQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 P+ + ++V+ YGPG+E G V P+ FTV+ AG+ + V+ I ++ A + + L + V+YIP++ G+ ++ V ++ +P SPF V+ ++ + KV VTG G++P+ + K P+ F I +DAG E+++ P N SV V + T+ C+Y + G ++V V Y +P SPF V V S+A+ + G V VG + T+ AG+G + +GP G N++ ++ Y Y P K G Y + + F + + S + P+++ SI + + ++ T F V GP +A + C +NGDG+ V+Y P+ G + + + + + I SPF + +P V A GPGL ++ FT+ AG L + V+ +K ++ +N +GT V+Y P + + + + + SP + G P +++ G +R + N++A I+ T E C + ++ + P G + + G+ +P K+ V + + S++K+ DGL ++ N F+VD G G LS +I PSK+ D + Y P E G + I + Y + VPGSPF VN+ S R + E + + G + ++ PS + C D + ++ + G + ++++ ++H+ GSPF+ V +D P KV + G G+E G ++ F + EAG G +++ + +D + G+C V Y + G + C +KF++ VP SPF++ + S+P K + N+ + + A+L A F I+ I+ + +P K + ++ Y V FVP E G + + + I GSPF++ + + +G + VD AG+GA+T I G V ++ E + ++ Y N PGDY I++K+GG + GS A+ S Y ++ I E T ++ +TQ S+ N K +EI R+ L GG+ V+ VR P +V+ + +NR V Y +E+G H L+V++ V GSPF+ V Sbjct: 247 PLRPKTNPNRVRAYGPGIEPIGPVVGAPANFTVETFSAGKGSVDVD-IQGPNGEIEKADVRFNNDKNLTYTVSYIPKSEGSHKVAVKFSGRDIPKSPFPVKVEGHAGDASKVKVTGPGIQPNG---VTIKKPTFFDILAKDAGRGVPEVIIIDPANHKTSVAAKVRQLENDTWRCEYVTALQGLHSVNVFYAGTPIPNSPFPVKVAPLSDARKVRASGRGLQATGVRVGDDADFKIYTEGAGEGEPEVRVIGPGGMNQNVMQSKVDGNTY---ECHYYPTKEGRYVIMVTFAGQEVAK-SPFEVKVGPKKESSIVAYGPGLSSGVIGYPAAFVVETNGETGALGFTVAGP----SQAEIECH----------DNGDGSALVKYHPTAVGEYAVHILCDNEDIPKSPF---IAQILPRTDFHPELVKASGPGLEKNGVTINQPTSFTVDPSKAGNAPLDVVVQDVFGTKLPVELKNNPDGTKKVTYTPTSGVPHTVEVNYGGVSTPNSPHRVYV-GVPVDAAKVQAFGPWLQPGVRPNAATHFNVDAREAGDAELKVKIIHEETKIEVPCRIIDNEDNTYSVEVIPPSKGAYTTTMTYGGQRVPLGE-KVVV--EQTVDVSKIKV--DGLEPSVIMNAATDFMVDMSKVGSNIDSGKLSCAIFDPMGHVLPSKI---VQGPTDDIFRIMYTPFEAGRHTIELMYDNIPVPGSPFVVNV---KSGCDPARCKAYGPGLEKGLTNQKNKFTVETKGAGNGGLSLAIEGPSEAKMTC--TDNRDGSCDVDYLATDPGEYDITIRFADKHIPGSPFRVLVEETVD--PSKVKVYGPGIEHGQVRESVPTFFNVDVGEAGPGRIAVKLTNSEGIPVDNLRVEDKGNCIYAVHYVPPKAGSVLTCQVKFSEVEVPCSPFVMTV-----FPKSEPTKVKVKGVNEKKK-TPASL---------PAEFEIDTKQAGQADINVAIKNPKGKAMQPRLEEVSTGTYVVSFVPDECGTYQCSIKYGDKEIEGSPFKLEAFPTGEAKKCKLVEQAPKIQTSGSQSHLKVDAREAGDGAVTCKITNKAGSEIVDIDVIEKDGFFDILYALNDPGDYDINVKFGGKDIPNGSFSIKAVESIEQYSHSEYIEE-----HTTKVVQQTTQ---SELVNGK--------SEITYRSVAFEKLPLPTTGGN-----VTAEVRMPSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHV 1423
BLAST of Filamin vs. TrEMBL
Match: A0A504ZB76 (Filamin-A OS=Fasciola gigantica OX=46835 GN=FGIG_01162 PE=4 SV=1) HSP 1 Score: 2853.16 bits (7395), Expect = 0.000e+0 Identity = 1443/2535 (56.92%), Postives = 1811/2535 (71.44%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSN----------------------------------SDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILT----PFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPK-STPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYA-----FQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXX-----XXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQK-GPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 +AERELAEDA+WK+IQKNTFTRWAN+HL+P NLI+DDLQYD ADGLKLI LV+ LSG F+H +++P+FRTQKLENVTMVLRFLEE+EGLRLVNIDS+DI DCR KLILGLIWTLILHYSIT+PLWEGE GQG+GP+PKQRLL W+N+K+ +PVKNFT+DWNDGTAIGALVDACAPGLCP+W QW+PKQ L+NA+EA+N AE+ L+V LI+P EMINP+VDEKAMMTYLSQFP+A+L APL PK+ VRAYGPGLE GNT+GNPA FT+DTF+AG+G +++IVLNPKGQ+EPC+I + +++ YSC+Y+PT EGEYR+IIKFA EI NSPFKV V+ A GDPSK +ASGPGIEP GN+ GRRTFFN+FTA AGPG+VDCVILD G +DS+KP ITKQ E+ +L+EYT K+EGLHSVNVFFAG QI SPFGVMV K S D KQAYATGRGIQP+GVRVRD+A+F+VHTEDAG L V V P C ++K L++C+Y PQR GP+ V ++YG + I LSPFNVDV PYK+S+I+AFGPGLTGG+V+KPA F VETNGETGALGFSI+GPSEA+IDC DNGDGSA V YWPTVPGEYAVHILC+DENIPKSPYM I+ D DP +V +GPG+ +G +P +F V+ ++AG P+ + EC D G+ + +++RDN DGTY+C YTPK+P KHT++VSYG VN+P SPF+V+V E ++V+GPG+E T+F VDCKLAG G++GIS+ DE RDVP+ T D DGTF + YT T GPTYT+ +FF+ E+P+SPF+VP++ + D K + NL+ + P+G+ EF+++T P SK +P ++VK PNG R+P + E+ +GF FTPTV+GPH+V V+ G P+ SP++ AT P+ PVQ A + PV + +Q + P I E A L V AYG+GL + A PA F IDS + PPAPL VTIEGP EAKI+Y+DNGDGTC V YLP EPG Y+VNVLY D HIK SPF V + P + DV++V AYGPGL PTGV K+SF+KFTV+AKP+D G+G+VKAI+ +P QR+ C V NN DGT+SCSYSP DG H +++TYDG PV SP+ V V G DPSR+RAYGPGLE G+T + Q+FTVDL+GAGQG LGL++EGPADAQIQC DNKDGTC+V YLP K G+YDV +KFN+ +IPGSPF VPI D VD S+V+CYGPGLE G+R P+ FTVDAS+AG+AP+ V +D +S PA ++P+ P ++DVTY+P G C+IEV V SPF Q+VL + EP++V VTGEGV P R + P+ F ++TR+AG DLEL V+ P + + L+V +HGDGT++C Y+ V G +TV+V +G + +P SP++VPV + + C IE + +PVG+ I VNT AG G ++ + + P G I G + Y P G Y V++ F + +PNG Q A P+ ER H T + T Y VDFK PVGP F +V +V+ PS R P L++NGDGT+T Q+QP+E GLHELE+ YNGQPI GSPF+FYV++ + SG VTAYGPGLSYGR A FT+VTK+AGAGGLSL+VEGPSKAEIQC DNKNGTC VSYLPL PG+Y I IKFM+ HI GSPFTA I GEP++ +Q+CVGTTS++PLRI+ETDI NL A V SP+G+E+ TLKRL NG+LGISFTP+E+GEH VNV R+GRHI NSPFKI+VGENEIGNASRV++YG+GL +G N+ CQF VDTRNAGYG LSLSIEGPSK +IECHDNHDGTCLVTY+PTEPGTYIINV+YAD VPGSPF V IGG PS + ERI R ++ A+V+ +G+ CELNL IPG N R+ A+V SP+G + C+++AL D ++IRF+P+E+GVHTVSV++ H+ GSPFQFTVG + DGG HKVH G G+++GL N F+IYTREAGAG LSIAIEGPSKAEIDF+D KDGSCGV+YRV EPG+Y CSI+FNDEH+PGSPF + I+E ++ P + R +S+A +QD+G IG F +NY G+T G++ AYV+SPS A + ++D +Q++V F P ENG H VHVL++ PIPGSPFRVV G VT SGEG+ HG G N FFVDT +AG+GAL+VT+DGPSKVQLNC E +GY F+Y+P PG+Y I+IKYG HIIGSPF ++G+ Q ++ T + +T SG Q G S+P V C G GL+ A + + N F V+A AG DVLYVGVSGPV CEEVNIKHLG ++ VNY V+++GRHL+MV+WG VPGSPF + V Sbjct: 26 MAERELAEDAEWKLIQKNTFTRWANEHLRPKNLIVDDLQYDFADGLKLIGLVEALSGQQFKHVNRKPSFRTQKLENVTMVLRFLEENEGLRLVNIDSTDIVDCRSKLILGLIWTLILHYSITIPLWEGE---VDHGQGQGPTPKQRLLSWLNNKLVDRPVKNFTSDWNDGTAIGALVDACAPGLCPDWRQWEPKQNLRNAREAMNAAEQWLDVPQLIRPEEMINPRVDEKAMMTYLSQFPSAKLKEGAPLRPKSTPEMVRAYGPGLERHGNTVGNPARFTIDTFSAGRGGVEVIVLNPKGQREPCDILSNNDRQQTYSCAYVPTQEGEYRVIIKFATKEILNSPFKVMVEGAQGDPSKASASGPGIEPQGNQAGRRTFFNIFTAAAGPGNVDCVILDPHGGRDSIKPVITKQGEDNYLVEYTPKDEGLHSVNVFFAGQQIPKSPFGVMVGPKPSAPLLMQPPTPLMTGSEEPIQAMQAPRKMSAPRRPACDPKQAYATGRGIQPQGVRVRDLADFKVHTEDAGEGPLEVAVIAPDGREIPCNVRKTGAYLFDCNYTPQRAGPHQVHVRYGGDHIMLSPFNVDVGPYKDSRIRAFGPGLTGGVVNKPAVFVVETNGETGALGFSIEGPSEARIDCTDNGDGSATVAYWPTVPGEYAVHILCNDENIPKSPYMVPIEPDMGKCDPERVKVHGPGVQPTGNVAGQPTEFTVDIRDAGGPAPLTVECRDNEGEPVALKVRDNGDGTYTCNYTPKVPRKHTILVSYGAVNVPRSPFRVDVAEPSQPGKVRVFGPGVESVIRGQPTHFTVDCKLAGQGNVGISITDEMGRDVPMDTQDMRDGTFRVAYTAHTPGPTYTVHVFFNNQEVPRSPFRVPVKPNIDMSKIHVENLSPSIPVGKPTEFDVITAGAGPPSNSKPQPNVVVKGPNGMRIPSTMTESVDGFTPSFTPTVVGPHSVAVDVGGVPVKGSPFRTNAT------------------------------PAPPVQDA-ICPV--------VDVPRQHAAITPLSAI--------EAAGL----VRAYGDGLHRATAGRPAQFTIDSRDAPPAPLSVTIEGPAEAKINYMDNGDGTCGVEYLPVEPGPYVVNVLYKDTHIKGSPFPVRVVPPGREHV---DVSRVHAYGPGLQPTGVLKESFAKFTVDAKPVDPQGRGLVKAIVVSPTKQRTACIVKNNGDGTWSCSYSPIDDGLHHVEVTYDGAPVNGSPFPVNVAPGCDPSRVRAYGPGLEGGMTHELQRFTVDLDGAGQGALGLALEGPADAQIQCHDNKDGTCTVDYLPTKAGTYDVFVKFNDMNIPGSPFAVPIKDKVDPSRVRCYGPGLEPRGARAQQPATFTVDASQAGDAPIHVATVDRLGRST-PAHVVPRPGQPNIYDVTYVPATEGPCQIEVRQGQSHVARSPFTQHVLPAYEPQRVRVTGEGVHPSRPLGLPATQPTSFHVDTREAGMGDLELSVSDPEAQPLQLEVVDHGDGTYSCHYRPVVVGRHTVRVKFGGQEIPESPYLVPVAPSGRADLCRIESGNESRIPVGQECVITVNTAQAGIGQVTCRIITPSGAQADVEIHEAGNGRVNIYYTPPIRGDYLVEVRFGGDLVPNGRFNQKAVTADELTPEVVIQEERVQHVSTQSIHSSTLVTGYHPVDFKLPVGPTFSHVDGLVHTPSGRTMRPTLLDNGDGTVTAQFQPNEPGLHELEITYNGQPIPGSPFRFYVEA-VGSGNVTAYGPGLSYGRSGEPADFTLVTKEAGAGGLSLSVEGPSKAEIQCHDNKNGTCSVSYLPLVPGEYTISIKFMENHIPGSPFTAHIAGEPRRFNQVCVGTTSEMPLRITETDIYNLVATVRSPSGQEQPSTLKRLPNGHLGISFTPREIGEHYVNVFRNGRHIANSPFKIYVGENEIGNASRVRIYGNGLREGTANQNCQFTVDTRNAGYGSLSLSIEGPSKADIECHDNHDGTCLVTYRPTEPGTYIINVRYADQTVPGSPFVVQIGGEPSLRMMERITRQRELADVTHVGSQCELNLKIPGINIRDLVATVTSPTGVTQRCDVVALDDVNYTIRFVPQEMGVHTVSVRNRGAHIPGSPFQFTVGAITDGGAHKVHAAGPGLQQGLTYSPNDFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKDGSCGVSYRVTEPGEYQCSIRFNDEHIPGSPFRVVINEAIERTFLSP---------EMRQLSVATVQDRGLMIGRPTAFTVNYTGMT-GALRAYVVSPSGAHTDALVHRVDVDQHAVRFTPSENGPHLVHVLMDERPIPGSPFRVVVGQDDQGLVTASGEGLTHGRVGERNRFFVDTMHAGSGALSVTVDGPSKVQLNCNERPNGYEFSYLPFLPGEYLINIKYGDMQHIIGSPFKAYVTGDAIQETYAVDSTHVVVET--RASGMQQSLGESRPSRVICTGSGLQQAYLNQTNTFTVNATQAGHDVLYVGVSGPVVACEEVNIKHLGQGQYAVNYVVRDRGRHLIMVKWGEQHVPGSPFVVDV 2489 HSP 2 Score: 157.532 bits (397), Expect = 3.142e-34 Identity = 123/416 (29.57%), Postives = 197/416 (47.36%), Query Frame = 2 Query: 3215 VTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNE-KHIPGSPFTVPI--------------HDIVDV--------------SKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVID--TATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVL 4369 V A G GL +G+ +P F I + E L + IEGP +A+ID+ D DG+C V+Y EPG Y ++ +NDEHI SPF V I + + ++ +++ + G+ + FTVN + G ++A + +P + V ++ ++P+ +G H + + D P+ SP+ V V Q D + A G GL G + +F VD AG G L ++++GP+ Q+ C + +G YLP PG Y ++IK+ + +HI GSPF + H +V+ S+V C G GL++ + + + FTV+A++AG L V V A + V + G + V Y+ + G I V + VPGSPFV +VL Sbjct: 2089 VHAAGPGLQQGLTYSPNDFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKDGSCGVSYRVTEPGEYQCSIRFNDEHIPGSPFRVVINEAIERTFLSPEMRQLSVAT--VQDRGLMIGRPTAFTVNYTGM----TGALRAYVVSPSGAHTDALVHRVDVDQHAVRFTPSENGPHLVHVLMDERPIPGSPFRVVVGQ-DDQGLVTASGEGLTHGRVGERNRFFVDTMHAGSGALSVTVDGPSKVQLNCNERPNGY-EFSYLPFLPGEYLINIKYGDMQHIIGSPFKAYVTGDAIQETYAVDSTHVVVETRASGMQQSLGESRPSRVICTGSGLQQ--AYLNQTNTFTVNATQAGHDVLYVGVSGPVVACEEVNIKHL----GQGQYAVNYVVRDRGRHLIMVKWGEQHVPGSPFVVDVL 2490 HSP 3 Score: 116.701 bits (291), Expect = 8.178e-22 Identity = 125/495 (25.25%), Postives = 210/495 (42.42%), Query Frame = 2 Query: 1037 NLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA-GDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVI-------LDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNS----DAKQ-AYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDD-ENIPKSPYMAQIQLD----TKLFD---------------------PLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIP---VQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVI 2392 +L V +P G + C++ ++ Y+ ++P G + + ++ + IP SPF+ V G KV A+GPG++ F+++T EAG G + I +D + RKD + Y E G + ++ F I SPF V+++ + + +Q + AT +Q G+ + F V+ A L V P + + +V + + P GP++V + PI SPF V V + + A G GLT G V + F V+T + +GAL ++ GPS+ +++C + +G +Y P +PGEY ++I D ++I SP+ A + D T D P +V G GL N+ F VN AG V+G + V I+ G Y+ Y + G+H ++V +G ++P SPF V+V+ Sbjct: 2021 DLVATVTSPTGVTQRCDVVAL--DDVNYTIRFVPQEMGVHTVSVRNRGAHIPGSPFQFTVGAITDGGAHKVHAAGPGLQ--QGLTYSPNDFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKD-----------GSCGVSYRVTEPGEYQCSIRFNDEHIPGSPFRVVINEAIERTFLSPEMRQLSVAT---VQDRGLMIGRPTAFTVNYTGMTGA-LRAYVVSPSGAHTDALVHRVDVDQHAVRFTPSENGPHLVHVLMDERPIPGSPFRVVVGQDDQGLVTASGEGLTHGRVGERNRFFVDTMHAGSGALSVTVDGPSKVQLNCNERPNGY-EFSYLPFLPGEYLINIKYGDMQHIIGSPFKAYVTGDAIQETYAVDSTHVVVETRASGMQQSLGESRPSRVICTGSGLQQAY-LNQTNTFTVNATQAGH----DVLYVGVSGPVVACEEVNIKHLGQGQYAVNYVVRDRGRHLIMVKWGEQHVPGSPFVVDVL 2490
BLAST of Filamin vs. TrEMBL
Match: A0A4E0RU07 (Filamin-A OS=Fasciola hepatica OX=6192 GN=D915_004146 PE=4 SV=1) HSP 1 Score: 2848.54 bits (7383), Expect = 0.000e+0 Identity = 1438/2535 (56.73%), Postives = 1806/2535 (71.24%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSN----------------------------------SDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILT----PFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPK-STPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYA-----FQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXX-----XXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQK-GPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 +AERELAEDA+WK+IQKNTFTRWAN+HL+P NLI+DDLQYD ADGLKLI LV+ LSG F+H +++P+FRTQKLENVTMVLRFLEE+EGLRLVNIDS+DI DCR KLILGLIWTLILHYSIT+PLWEGE GQG+GP+PKQRLL W+N+K+ +PVKNFT+DWNDGTAIGALVDACAPGLCP+W QW+PKQ L+NA+EA+N AE+ L+V LI+P EMINP+VDEKAMMTYLSQFP+A+L APL PK+ VRAYGPGLE GNT+GNPA FT+DTF+AG+G +++IVLNPKGQ+EPC+I + +++ YSC+Y+PT EGEYR+IIKFA EI NSPFKV V+ A GD SK +ASGPGIEP GN+ GRRTFFN+FTA AGPG+VDCVILD G +DS+KP ITKQ E+ +L+EYT K+EGLHSVNVFFAG QI SPFGVMV K S D KQAYATGRGIQP+GVRVRD+A+F+VHTEDAG L V V P C ++K L++C+Y PQR GP+ V ++YG + I LSPFNVDV PYK+S+I+AFGPGLTGG+V+KPA F VETNGETGALGFSI+GPSEA+IDC DNGDGSA V YWPTVPGEYAVHILC+DENIPKSPYM I+ D DP +V +GPG+ +G +P +F V+ ++AG P+ + EC D G+ + +++RDN DGTY+C YTPK+P KHT++VSYG VN+P SPF+V+V E ++V+GPG+E T+F VDCKLAG G++GIS+ DE RDVP+ T D DGTF + YT T GPTYT+ +FF+ E+P+SPF+VP++ + D K + NL+ + P+G+ EF+++T P SK +P ++VK PNG R+P + E+ +GF FTPTV+GPH+V V+ G P+ SP+ R N P + + D +P Q A +TP+ E A L V AYG+GL + A PA F IDS + PPAPL VTIEGP EAKI+Y+DNGDGTC V YLP EPG Y+VNVLY D HIK SPF V + P + DV++V AYGPGL PTGV K+SF+KFTV+AKP+D G+G+VKAI+ +P QR+ C V NN DGT+SCSYSP DG H +++TYDG PV SP+ V V G DPSR+RAYGPGLE G+T + Q+FTVDL+GAGQG LGL++EGPADAQIQC DNKDGTC+V YLP K G+YDV +KFN+ +IPGSPF VPI D VD S+V+CYGPGLE G+R P+ FTVDAS+AG+AP+ V +D +S PA ++P+ P ++DVTY+P G C+IEV V SPF Q+VL + EP++V VTGEGV P R + P+ F ++TR+AG DLEL V+ P + + L+V +HGDGT++C Y+ V G +TV+V +G + +P SP++VPV + + C IE + +PVG+ I VNT AG G ++ + + P G I G + Y P G Y V++ F + +PNG Q A P+ ER H T + T Y VDFK PVGP F +V +V+ PS R P L++NGDGT+T Q+QP+E GLHELE+ YNGQPI GSPF+FYV++ + SG VTAYGPGLSYGR A FT+VTK+AGAGGLSL+VEGPSKAEIQC DNKNGTC VSYLPL PG+Y I IKFM+ HI GSPFTA I GEP++ +Q+CVGTTS++PLRI+ETDI NL A V SP+G+E+ TLKRL NG+LGISFTP+E+GEH VNV R+GRHI NSPFKI+VGENEIGNASRV++YG+GL +G N+ CQF VDTRNAGYG LSLSIEGPSK +IECHDNHDGTCLVTY+PTEPGTYIINV+YAD VPGSPF V IGG PS + ERI R ++ A+V+ +G+ CELNL IPG N R+ A+V SP+G + C+++AL D ++IRF+P+E+GVHTVSV++ H+ GSPFQFTVG + DGG HKVH G G+++GL N F+IYTREAGAG LSIAIEGPSKAEIDF+D KDGSCGV+YRV EPG+Y CSI+FNDEH+PGSP+ + I+E ++ P + R +S+A +QD+G IG F +NY G+T G++ AYV+SPS A + ++D +Q++V F P ENG H VHVL++ PIPGSPFRVV G VT SGEG+ HG G N FFVDT +AG+GAL+VT+DGPSKVQLNC E +GY F+Y+P PG+Y I+IKYG HIIGSPF ++G+ Q ++ T + +T SG Q G S+P V C G GL+ A + + N F V+A AG DVLYVGVSGPV CEEVNIKHLG ++ VNY V+++GRHL+MV+WG VPGSPF + V Sbjct: 26 MAERELAEDAEWKLIQKNTFTRWANEHLRPKNLIVDDLQYDFADGLKLIGLVEALSGQQFKHVNRKPSFRTQKLENVTMVLRFLEENEGLRLVNIDSTDIVDCRSKLILGLIWTLILHYSITIPLWEGE---VDHGQGQGPTPKQRLLSWLNNKLVDRPVKNFTSDWNDGTAIGALVDACAPGLCPDWRQWEPKQNLRNAREAMNAAEQWLDVPQLIRPEEMINPRVDEKAMMTYLSQFPSAKLKEGAPLRPKSTPEMVRAYGPGLERHGNTVGNPARFTIDTFSAGRGGVEVIVLNPKGQREPCDILSNNDRQQTYSCAYVPTQEGEYRVIIKFATKEILNSPFKVMVEGAQGDASKASASGPGIEPQGNQAGRRTFFNIFTAAAGPGNVDCVILDPHGGRDSIKPVITKQGEDNYLVEYTPKDEGLHSVNVFFAGQQIPKSPFGVMVGPKPSAPLLMQPPTPLMTGSEEPIQAMQAPRKMSAPRRPACDPKQAYATGRGIQPQGVRVRDLADFKVHTEDAGEGPLEVAVIAPDGREIPCNVRKTGAYLFDCNYTPQRAGPHQVHVRYGGDHIMLSPFNVDVGPYKDSRIRAFGPGLTGGVVNKPAVFVVETNGETGALGFSIEGPSEARIDCTDNGDGSATVAYWPTVPGEYAVHILCNDENIPKSPYMVPIEPDMGKCDPERVKVHGPGVQPTGNVAGQPTEFTVDIRDAGGPAPLTVECRDNEGEPVALKVRDNGDGTYTCNYTPKVPRKHTILVSYGAVNVPRSPFRVDVAEPSQPGKVRVFGPGVESVIRGQPTHFTVDCKLAGQGNVGISITDEMGRDVPMDTQDMRDGTFRVAYTAHTPGPTYTVHVFFNNQEVPRSPFRVPVKPNIDMSKIHVENLSPSIPVGKPTEFDVITAGAGPPSNSKPQPNVVVKGPNGMRIPSTMTESVDGFTPSFTPTVVGPHSVAVDVGGVPVKGSPF------RTNATPAPPVQDAICPVVD------------VPRQHAAITPLS-----------------------------ALEAAGL----VRAYGDGLHRATAGRPAQFTIDSRDAPPAPLSVTIEGPAEAKINYMDNGDGTCGVEYLPVEPGPYVVNVLYKDTHIKGSPFPVRVVPPGREHV---DVSRVHAYGPGLQPTGVLKESFAKFTVDAKPVDPQGRGLVKAIVVSPTKQRTACIVKNNGDGTWSCSYSPIDDGLHHVEVTYDGAPVNGSPFPVNVAPGCDPSRVRAYGPGLEGGMTHELQRFTVDLDGAGQGALGLALEGPADAQIQCHDNKDGTCTVDYLPTKAGTYDVFVKFNDMNIPGSPFAVPIKDKVDPSRVRCYGPGLEPRGARAQQPATFTVDASQAGDAPIHVATVDRLGRST-PAHVVPRPGQPNIYDVTYVPATEGPCQIEVRQGQSHVARSPFTQHVLPAYEPQRVRVTGEGVHPSRPLGLPATQPTSFHVDTREAGMGDLELSVSDPEAQPLQLEVVDHGDGTYSCHYRPIVVGRHTVRVKFGGQEIPESPYLVPVAPSGRADLCRIESGNESRIPVGQECVITVNTAQAGIGQVTCRIITPSGAQADVEIHEAGNGRVNIYYTPPIRGDYLVEVRFGGDLVPNGRFNQRAVTADELTPEVVIQEERVQHMSTQSIHSSTLVTGYHPVDFKLPVGPTFSHVDGLVHTPSGRTMRPTLLDNGDGTVTAQFQPNEPGLHELEITYNGQPIPGSPFRFYVEA-VGSGNVTAYGPGLSYGRSGEPADFTLVTKEAGAGGLSLSVEGPSKAEIQCHDNKNGTCSVSYLPLVPGEYTISIKFMENHIPGSPFTAHIAGEPRRFNQVCVGTTSEMPLRITETDIYNLVATVRSPSGQEQPSTLKRLPNGHLGISFTPREIGEHYVNVFRNGRHIANSPFKIYVGENEIGNASRVRIYGNGLREGTANQNCQFTVDTRNAGYGSLSLSIEGPSKADIECHDNHDGTCLVTYRPTEPGTYIINVRYADQTVPGSPFVVQIGGEPSLRMMERITRQRELADVTHVGSQCELNLKIPGINIRDLVATVTSPTGVTQRCDVVALDDVNYTIRFVPQEMGVHTVSVRNRGAHIPGSPFQFTVGAITDGGAHKVHAAGPGLQQGLTYSPNDFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKDGSCGVSYRVTEPGEYQCSIRFNDEHIPGSPYRVVINEAIERTFLSP---------EMRQLSVATVQDRGLMIGRPTAFTVNYTGMT-GALRAYVVSPSGAHTDALVHRVDVDQHAVRFTPSENGPHLVHVLMDERPIPGSPFRVVVGQDDQGLVTASGEGLTHGRVGERNRFFVDTMHAGSGALSVTVDGPSKVQLNCNERPNGYEFSYLPFLPGEYLINIKYGDMQHIIGSPFKAYVTGDAIQETYAVDSTHVVVET--RASGMQQSLGESRPSRVICTGSGLQQAYLNQTNTFTVNATQAGHDVLYVGVSGPVVACEEVNIKHLGQGQYAVNYVVRDRGRHLIMVKWGEQHVPGSPFVVDV 2489 HSP 2 Score: 156.377 bits (394), Expect = 7.991e-34 Identity = 122/416 (29.33%), Postives = 197/416 (47.36%), Query Frame = 2 Query: 3215 VTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNE-KHIPGSPFTVPI--------------HDIVDV--------------SKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVID--TATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVL 4369 V A G GL +G+ +P F I + E L + IEGP +A+ID+ D DG+C V+Y EPG Y ++ +NDEHI SP+ V I + + ++ +++ + G+ + FTVN + G ++A + +P + V ++ ++P+ +G H + + D P+ SP+ V V Q D + A G GL G + +F VD AG G L ++++GP+ Q+ C + +G YLP PG Y ++IK+ + +HI GSPF + H +V+ S+V C G GL++ + + + FTV+A++AG L V V A + V + G + V Y+ + G I V + VPGSPFV +VL Sbjct: 2089 VHAAGPGLQQGLTYSPNDFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKDGSCGVSYRVTEPGEYQCSIRFNDEHIPGSPYRVVINEAIERTFLSPEMRQLSVAT--VQDRGLMIGRPTAFTVNYTGM----TGALRAYVVSPSGAHTDALVHRVDVDQHAVRFTPSENGPHLVHVLMDERPIPGSPFRVVVGQ-DDQGLVTASGEGLTHGRVGERNRFFVDTMHAGSGALSVTVDGPSKVQLNCNERPNGY-EFSYLPFLPGEYLINIKYGDMQHIIGSPFKAYVTGDAIQETYAVDSTHVVVETRASGMQQSLGESRPSRVICTGSGLQQ--AYLNQTNTFTVNATQAGHDVLYVGVSGPVVACEEVNIKHL----GQGQYAVNYVVRDRGRHLIMVKWGEQHVPGSPFVVDVL 2490 HSP 3 Score: 115.161 bits (287), Expect = 2.113e-21 Identity = 124/495 (25.05%), Postives = 210/495 (42.42%), Query Frame = 2 Query: 1037 NLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA-GDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVI-------LDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNS----DAKQ-AYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDD-ENIPKSPYMAQIQLD----TKLFD---------------------PLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIP---VQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVI 2392 +L V +P G + C++ ++ Y+ ++P G + + ++ + IP SPF+ V G KV A+GPG++ F+++T EAG G + I +D + RKD + Y E G + ++ F I SP+ V+++ + + +Q + AT +Q G+ + F V+ A L V P + + +V + + P GP++V + PI SPF V V + + A G GLT G V + F V+T + +GAL ++ GPS+ +++C + +G +Y P +PGEY ++I D ++I SP+ A + D T D P +V G GL N+ F VN AG V+G + V I+ G Y+ Y + G+H ++V +G ++P SPF V+V+ Sbjct: 2021 DLVATVTSPTGVTQRCDVVAL--DDVNYTIRFVPQEMGVHTVSVRNRGAHIPGSPFQFTVGAITDGGAHKVHAAGPGLQ--QGLTYSPNDFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKD-----------GSCGVSYRVTEPGEYQCSIRFNDEHIPGSPYRVVINEAIERTFLSPEMRQLSVAT---VQDRGLMIGRPTAFTVNYTGMTGA-LRAYVVSPSGAHTDALVHRVDVDQHAVRFTPSENGPHLVHVLMDERPIPGSPFRVVVGQDDQGLVTASGEGLTHGRVGERNRFFVDTMHAGSGALSVTVDGPSKVQLNCNERPNGY-EFSYLPFLPGEYLINIKYGDMQHIIGSPFKAYVTGDAIQETYAVDSTHVVVETRASGMQQSLGESRPSRVICTGSGLQQAY-LNQTNTFTVNATQAGH----DVLYVGVSGPVVACEEVNIKHLGQGQYAVNYVVRDRGRHLIMVKWGEQHVPGSPFVVDVL 2490
BLAST of Filamin vs. TrEMBL
Match: A0A4S2L3S3 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_010478 PE=4 SV=1) HSP 1 Score: 2816.95 bits (7301), Expect = 0.000e+0 Identity = 1423/2501 (56.90%), Postives = 1800/2501 (71.97%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILT----PFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPK-STPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYS--IERTTHHYTTE--QSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFR-----XXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPS--KPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 +AERELAEDA+WK+IQKNTFTRWAN+HLKP N+ ++DLQYDLADGL+LI LV+ LSG F+H +++P+FRTQKLENVTMVLRFLEE+EGLRLVNIDS+DI DCR KLILGLIWTLILHYSIT+PLWEGE + GQG+GP+PKQRLL W+N+K+ +PVKNFTTDWNDGTAIGALVDACAPGLCP+W QW+PKQ L+NA+EA+N AE+ L+V LI+P EMINP+VDEKAMMTYLSQFP+A+L APL PK+ VRAYGPGL+ GNT+GNPA FT+DTF+AG+G +++IVLNPKGQ+EPCEI + +++ YSC+Y+PT EGEYR+IIKFA EI NSPFKV V+ AAGD SK TASGPGIEP GN+ GRRTFFN+FTA AGPG+VDCVILD G +DS+KP ITKQ E+ +L+EYT ++EGLHSVNVFFAG QI +SPFGVMV DAKQAYATGRGIQP+GVRV+D+A+F+VHTEDAG L V V P C +K L++CSY PQR G + V ++YG + I LSPFNVDV PYK+S+I+AFGPGL+GG+V+KPA F VETNGETGALGFSI+GPSEA+IDC DNGDGSA V YWPT PGEYAVHILC+DENIPKSP+M I+ D DP +V +GPG++ +G +P +F+V+ ++AG P+ + EC D G+ + +++RDN DGTY+C YTPK+P KHTV+VSYG VN+P SPF+V V E ++V+GPG+E T+F VDCK AG G++GISV DE RDV + T D DGTF + YT T GPTYT+ +FF+ E+P+SPF+VP++ + D K + NL+ P+G+ EF+++T P +K RP ++VKSP+G RVP + ET +GF FTPTV GPHT+ V+ G P+ SP++ AT V +E P+ Y + N + +++P+E + + V AYG+GL + PA F IDS + PPAPL VTIEGP EAKI+Y DNGDGTC V YLP EPG Y VNVLY D HIK SPF V + P + DV++V AYGPGL PTGV K+SF+KFTV+AKP+D G G+VKAI+ NP QR+ C V NN DGT+ CSYSP DG H I++TYDG PV SP+ V V G DPSR+R YGPGLE G+T + Q+FTVDL+GAGQG LGL+IEGPADAQIQC DNKDGTC+V YLP K G YDV +KFN+ ++PGSPF VPI D VD S+V+CYGPGLE G+R P+ FTVDAS+AG+AP+ V +D +S PA +P+ S PG++DVTY+P G C+IEV + V SPF Q+VL + EP++V VTGEGV P R + +P+ F ++TRDAG DLEL V+ P + + L+V +HGDGT+TC Y+ + G +TV+V +G + +P SPF+VPV + + C IE VPVG+ I VNT AG G ++ + V P G I+ G V Y P G Y V++ F + +PNG Q A E S +E H TT QS I+ T Y VDFK PVGP+F +V +V PS R P LI+NGDGT+T Q+QP+E GLHELE+ YN QPI GSPF+FYV++ + SG V+AYGPGLSYGR A FT++T++AGAGGLSL+VEGPSKAEIQC DNKNGTC VSYLPL PG+Y I IKFM++HI GSPFTA + GE ++ +Q+CVGTTS++PLRI+ETDI NL A V SP+G+E+ +LKRL NG+LGISFTP+E+GEH VNV R+GRHI NSPFKI+VGE EIGNAS+V++YG+GL++G N+ CQF VDTRNAGYG LSLSIEGPSK +IECHDNHDGTCLVTY+PTEPGTYIINVKYAD V GSPF V+IGG PS + ERI R ++ A+V+ +G+ CELNL IPG + R+ TA+V SPSG + C+++ + D ++IRF+P+E+GVHTVSV+ H+ GSPFQFTVG + DGG HKVH G G++ GL N+F+IYTREAGAG LSIAIEGPSKAEIDF+D KDGSCG++YRV EPG+Y CS++FNDE++PGSPF + I+E ++ P + R +S+AA+QD+G IG F +NY G T G++ AY +SPS + A + ++D +Q+ V F P ENG H VHVL++ PIPGSPFR +G VT SGEG+ HG G N FFV+T+ AG+GAL+VT+DGPSKV+LNC E GY FTY+P APGDY I+I++G HIIGSPF ++G+ Q + T + +T + Q+ S +P V C G GL A + + N F V+A AG DVLYVGVSGPV CEEVNIKHLG ++ VNY V+++G+HL+M++WG+ VPGSPF + V Sbjct: 25 MAERELAEDAEWKLIQKNTFTRWANEHLKPKNVTVEDLQYDLADGLRLIGLVEALSGQQFKHVNRKPSFRTQKLENVTMVLRFLEENEGLRLVNIDSTDIVDCRSKLILGLIWTLILHYSITIPLWEGEIDH---GQGQGPTPKQRLLSWLNNKLVDRPVKNFTTDWNDGTAIGALVDACAPGLCPDWRQWEPKQNLRNAREAMNAAEQWLDVPQLIRPEEMINPRVDEKAMMTYLSQFPSAKLKEGAPLRPKSTPELVRAYGPGLQPHGNTVGNPARFTIDTFSAGRGQVEVIVLNPKGQREPCEILTNNDRQQTYSCAYVPTQEGEYRVIIKFATKEILNSPFKVMVEGAAGDASKATASGPGIEPQGNQAGRRTFFNIFTAAAGPGNVDCVILDPHGGRDSIKPVITKQGEDNYLVEYTPRDEGLHSVNVFFAGQQIPNSPFGVMVGPM---CDAKQAYATGRGIQPQGVRVKDLADFKVHTEDAGEGPLEVAVIAPDGREIPCTTRKTGAYLFDCSYNPQRAGLHQVHVRYGGDHIMLSPFNVDVGPYKDSRIRAFGPGLSGGVVNKPAVFVVETNGETGALGFSIEGPSEARIDCTDNGDGSATVAYWPTAPGEYAVHILCNDENIPKSPFMVPIEPDMGKCDPDRVKVHGPGVLPTGNVAGQPTEFVVDIRDAGGPAPLTVECRDNEGEPVALKVRDNGDGTYTCSYTPKVPRKHTVLVSYGTVNVPRSPFRVEVAEPSQPGKVRVFGPGVESVVRGEPTHFTVDCKQAGQGNVGISVTDETGRDVAMDTQDMRDGTFRVAYTANTPGPTYTVHVFFNNQEVPRSPFRVPVKPNIDMSKIHVENLSPNIPVGKPTEFDVITAGAGPPSNNKPRPNVVVKSPSGMRVPCTMAETVDGFTPSFTPTVAGPHTIAVDIAGMPVKGSPFRTQATPEVAIQE------PI-----YPVANAVQKHAPV----TQMSPIEAAGL------------------------------------VRAYGDGLHHATSGRPAHFTIDSRDAPPAPLSVTIEGPAEAKINYADNGDGTCGVEYLPMEPGPYTVNVLYKDIHIKGSPFPVRVAPPGREHI---DVSRVHAYGPGLQPTGVLKESFAKFTVDAKPVDPQGHGLVKAIVVNPHKQRTACLVQNNGDGTWKCSYSPVDDGLHHIEVTYDGAPVQGSPFPVNVAPGCDPSRVRVYGPGLEGGLTHELQRFTVDLDGAGQGALGLAIEGPADAQIQCHDNKDGTCTVDYLPTKAGPYDVFVKFNDMNVPGSPFQVPIRDRVDPSRVRCYGPGLEPRGARAQQPATFTVDASQAGDAPIYVATVDRLGRST-PAHTVPRPSQPGVYDVTYVPATEGPCQIEVRQGSAHVARSPFTQHVLPAFEPQRVRVTGEGVHPTRPLGLPATLPTSFHVDTRDAGMGDLELSVSDPEAQPLQLEVVDHGDGTYTCHYRPIIVGRHTVRVKFGGQEIPESPFLVPVAPSGRADLCRIESGNDGRVPVGQECVITVNTLQAGLGQVTCRIVTPSGATADVEIQEAPNGRVNVYYTPPIRGDYLVEVRFGGDLVPNGRFNQRAVTTDELISDTVEERVQHVTTHSVQSSTIV-TGYHPVDFKLPVGPMFSHVEGLVRTPSGRTVQPNLIDNGDGTVTAQFQPTEPGLHELEITYNRQPIPGSPFRFYVEA-VGSGNVSAYGPGLSYGRAGEPAEFTLITREAGAGGLSLSVEGPSKAEIQCHDNKNGTCSVSYLPLVPGEYTISIKFMERHIPGSPFTAHVGGETRRFNQVCVGTTSEMPLRITETDIYNLVATVRSPSGQEQPSSLKRLPNGHLGISFTPREIGEHYVNVFRNGRHIANSPFKIYVGEGEIGNASKVRIYGNGLHEGTANQNCQFTVDTRNAGYGSLSLSIEGPSKADIECHDNHDGTCLVTYRPTEPGTYIINVKYADQLVNGSPFVVHIGGEPSLRMMERITRQRELADVTHVGSQCELNLKIPGISLRDLTATVTSPSGVTQRCDVMPIDDVNYTIRFVPQEMGVHTVSVRHRGSHIPGSPFQFTVGAITDGGAHKVHAAGPGLQHGLTYTPNEFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKDGSCGISYRVTEPGEYQCSVRFNDENIPGSPFRVIINEAMERTFYSP---------EIRQLSVAAVQDRGLQIGRPTAFTVNYTG-TSGTLRAYAVSPSGVQIPAYVHQVDIDQHGVRFTPQENGPHLVHVLMDERPIPGSPFRIIVGQEDLGLVTASGEGLTHGRVGEKNRFFVNTTQAGSGALSVTVDGPSKVKLNCTERPDGYEFTYLPLAPGDYMINIRHGDQRHIIGSPFKAYVTGDAVQDIYNADTTHVVVETGSRFATGPQRSVSEARPDKVICTGSGLHQAFLNQTNTFNVNATQAGHDVLYVGVSGPVVACEEVNIKHLGLGQYAVNYLVRDRGQHLIMIKWGDEHVPGSPFVVNV 2452 HSP 2 Score: 125.946 bits (315), Expect = 1.383e-24 Identity = 131/502 (26.10%), Postives = 207/502 (41.24%), Query Frame = 2 Query: 1037 NLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA-GDPSKVTASGPGIEP----VGNEVGRRTFFNVFTAEAGPGSVDCVI-------LDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNS----DAKQAYATGRGIQPEGVRVRDVAEFQV-HTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIV-SKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDE-NIPKSPYMAQI----------------------------QLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIP---VQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVI 2392 +L V +P G + C++ P ++ Y+ ++P G + + ++ S IP SPF+ V G KV A+GPG++ NE F+++T EAG G + I +D + RKD I Y E G + +V F I SPF V+++ + + +Q +Q G+++ F V +T +G L P + +V + + PQ GP++V + PI SPF + V + A G GLT G V K FF T +GAL ++ GPS+ K++C + DG TY P PG+Y ++I D+ +I SP+ A + Q P KV G GL N+ F VN AG V+G + V I+ G Y+ Y + G+H +++ +G+ ++P SPF VNV+ Sbjct: 1981 DLTATVTSPSGVTQRCDVM--PIDDVNYTIRFVPQEMGVHTVSVRHRGSHIPGSPFQFTVGAITDGGAHKVHAAGPGLQHGLTYTPNE------FSIYTREAGAGGLSIAIEGPSKAEIDFEDRKD-----------GSCGISYRVTEPGEYQCSVRFNDENIPGSPFRVIINEAMERTFYSPEIRQLSVAA--VQDRGLQIGRPTAFTVNYTGTSG--TLRAYAVSPSGVQIPAYVHQVDIDQHGVRFTPQENGPHLVHVLMDERPIPGSPFRIIVGQEDLGLVTASGEGLTHGRVGEKNRFFVNTTQAGSGALSVTVDGPSKVKLNCTERPDGY-EFTYLPLAPGDYMINIRHGDQRHIIGSPFKAYVTGDAVQDIYNADTTHVVVETGSRFATGPQRSVSEARPDKVICTGSGLHQAF-LNQTNTFNVNATQAGH----DVLYVGVSGPVVACEEVNIKHLGLGQYAVNYLVRDRGQHLIMIKWGDEHVPGSPFVVNVV 2453
BLAST of Filamin vs. TrEMBL
Match: G7Y5W0 (Filamin OS=Clonorchis sinensis OX=79923 GN=CLF_101494 PE=4 SV=1) HSP 1 Score: 2811.56 bits (7287), Expect = 0.000e+0 Identity = 1423/2542 (55.98%), Postives = 1804/2542 (70.97%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNS------------------------------------------DAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILT----PFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPK-STPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYS--IERTTHHYTTEQSKP-IIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXX-----XXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQK--GPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 +AERELAEDA+WK+IQKNTFTRWAN+HLKP N+ +DDLQYDLADGL+LI LV+ LSG F+H +++P+FRTQKLENVTMVLRFLEE+EGLRLVNIDS+DI DCR KLILGLIWTLILHYSIT+PLWEGE + GQG+GP+PKQRLL W+N+K+ +PVKNFTTDWNDGTAIGALVDACAPGLCP+W QW+PKQ L+NA+EA+N AE+ L+V LI+P EMINP+VDEKAMMTYLSQFP+A+L APL PK+ VRAYGPGL+ GNT+GNPA FT+DTF+AG+G +++IVLNPKGQ+EPCEI + +++ YSC+Y+PT EGEYR+IIKFA EI NSPFKV V+ AAGD SK TASGPGIEP GN+ GRRTFFN+FTA AGPG+VDCVILD G +DS+KP ITKQ E+ +L+EYT ++EGLHSVNVFFAG QI +SPFGVMV K + DAKQAYATGRGIQP+GVRV+D+A+F+VHTEDAG L V V P C +K L++CSY PQR G + V ++YG + I LSPFNVDV PYK+S+I+AFGPGL+GG+V+KPA F VETNGETGALGFSI+GPSEA+IDC DNGDGSA V YWPT PGEYAVHILC+DENIPKSP+M I+ D DP +V +GPG++ +G +P +F+V+ ++AG P+ + EC D G+ + +++RDN DGTY+C YTPK+P KHTV+VSYG VN+P SPF+V V E ++V+GPG+E T+F VDCK AG G++GISV DE RDV + T D DGTF + YT T GPTYT+ +FF+ E+P+SPF+VP++ + D K + NL+ P+G+ EF+++T P +K RP ++VKSP+G RVP + ET +GF FTPTV GPHTV V+ G P+ SP+++ AT V +E P+ Y + N + +++P+E S + V AYG+GL + PA F IDS + PPAPL VTIEGP EAKI+Y DNGDGTC V YLP EPG Y VNVLY D HIK SPF V + P + DV++V AYGPGL PTGV K+SF+KFTV+AKP+D G G+VKAI+ NP QR+ C V NN DGT+ CSYSP DG H I++TYDG PV SP+ V V G DPSR+R YGPGLE G+T + Q+FTVDL+GAGQG LGL+IEGPADAQIQC DNKDGTC+V YLP K G YDV +KFN+ ++PGSPF VPI D VD S+V+CYGPGLE G+R P+ FTVDAS+AG+AP+ V +D +S PA +P+ S PG++DVTY+P G C+IEV + V SPF Q+VL + EP++V VTGEGV P R + P+ F ++TRDAG DLEL V+ P + + L+V +HGDGT+TC Y+ + G +TV+V +G + +P SPF+VPV + + C IE VPVG+ I VNT AG G ++ + V P G I+ G + Y P G Y V++ F + +PNG Q A E S +E H TT + I T Y VDFK PVGP+F +V +V PS R P LI+NGDGT+T Q+QP+E GLHELE+ YNGQPI GSPF+FYV++ + SG V+AYGPGLSYGR A FT+VT++AGAGGLSL+VEGPSKAEIQC DNKNGTC VSYLPL PG+Y I IKFM++HI GSPFTA + GE ++ +Q+CVGTTS++PLRI+ETDI NL A V SP+G+E+ +LKRL NG+LGISFTP+E+GEH VNV R+GRHI NSPFKI+VGE EIGNAS+V++YG+GL++G N+ CQF VDTRNAGYG LSLSIEGPSK +IECHDNHDGTCLVTY+PTEPGTYIINVKYAD V GSPF V+IGG PS + ERI R ++ A+V+ +G+ CELNL IPG + R+ TA+V SPSG + C+++ + D ++IRF+P+E+GVHTVSV+ H+ GSPFQFTVG + DGG HKVH G G++ GL N+F+IYTREAGAG LSIAIEGPSKAEIDF+D KDGSCG++YRV EPG+Y CS++FNDE++PGSPF + I+E ++ P + R +S+AA+QD+G IG F +NY G++ G++ AY +SPS + A + ++D +Q+ V F P ENG H VHVL++ PIPGSPFR++VG+ T SGEG+ HG G N FFV+T+ AG+GAL+VT+DGPSKV+LNC E GY FTY+P APGDY I+I++G HIIGSPF ++G+ Q + T + +T ++ Q+ +P V C G GL A + + N F V+A AG DVLYVGVSGPV CEEVN+KHLG ++ VNY V+++G+HL+M++WG+ VPGSPF + V Sbjct: 25 MAERELAEDAEWKLIQKNTFTRWANEHLKPKNVTVDDLQYDLADGLRLIGLVEALSGQQFKHVNRKPSFRTQKLENVTMVLRFLEENEGLRLVNIDSTDIVDCRSKLILGLIWTLILHYSITIPLWEGEIDH---GQGQGPTPKQRLLSWLNNKLVDRPVKNFTTDWNDGTAIGALVDACAPGLCPDWRQWEPKQNLRNAREAMNAAEQWLDVPQLIRPEEMINPRVDEKAMMTYLSQFPSAKLKEGAPLRPKSTPELVRAYGPGLQPHGNTVGNPARFTIDTFSAGRGQVEVIVLNPKGQREPCEILTNNDRQQTYSCAYVPTQEGEYRVIIKFATKEILNSPFKVMVEGAAGDASKATASGPGIEPQGNQAGRRTFFNIFTAAAGPGNVDCVILDPHGGRDSIKPVITKQGEDNYLVEYTPRDEGLHSVNVFFAGQQIPNSPFGVMVGPKPAVQPPIQPSLQPLIQSPAPIMPSREEPIQAMTAPRKMSVPKRPVCDAKQAYATGRGIQPQGVRVKDLADFKVHTEDAGEGPLEVAVIAPDGREIPCTTRKTGAYLFDCSYNPQRAGLHQVHVRYGGDHIMLSPFNVDVGPYKDSRIRAFGPGLSGGVVNKPAVFVVETNGETGALGFSIEGPSEARIDCTDNGDGSATVAYWPTAPGEYAVHILCNDENIPKSPFMVPIEPDMGKCDPDRVKVHGPGVMPTGNVAGQPTEFVVDIRDAGGPAPLTVECRDNEGEPVALKVRDNGDGTYTCSYTPKVPRKHTVLVSYGTVNVPRSPFRVEVAEPSQPGKVRVFGPGVESVVRGEPTHFTVDCKQAGQGNVGISVTDETGRDVAMDTQDMRDGTFRVAYTANTPGPTYTVHVFFNNQEVPRSPFRVPVKPNIDMSKIHVENLSPNIPVGKSTEFDVITAGAGPPSNNKPRPNVVVKSPSGMRVPCTMAETVDGFTPSFTPTVAGPHTVAVDIAGMPVKGSPFRIQATPEVAIQE------PI-----YPVANAVQKHAPV----TQMSPIEASGL------------------------------------VRAYGDGLHHATSGRPAHFTIDSRDAPPAPLSVTIEGPAEAKINYADNGDGTCGVEYLPMEPGPYTVNVLYKDIHIKGSPFPVRVAPPGREHI---DVSRVHAYGPGLQPTGVLKESFAKFTVDAKPVDPQGHGLVKAIVVNPHKQRTACLVQNNGDGTWKCSYSPVDDGLHHIEVTYDGAPVQGSPFPVNVAPGCDPSRVRVYGPGLEGGLTHELQRFTVDLDGAGQGALGLAIEGPADAQIQCHDNKDGTCTVDYLPTKAGPYDVFVKFNDMNVPGSPFQVPIRDRVDPSRVRCYGPGLEPRGARAQQPATFTVDASQAGDAPIYVATVDRLGRST-PAHTVPRPSQPGVYDVTYVPATEGPCQIEVRQGSAHVARSPFTQHVLPAFEPQRVRVTGEGVHPTRPLGLPATQPTSFHVDTRDAGMGDLELSVSDPEAQPLQLEVVDHGDGTYTCHYRPIIVGRHTVRVKFGGQEIPESPFLVPVAPSGRADLCRIESGNDGRVPVGQECVITVNTLQAGLGQVTCRIVTPSGATADVEIQEAPNGRVNIYYTPPIRGDYLVEVRFGGDLVPNGRFNQRAVTTDELISDTVEERVQHVTTHSVQSSTIMTGYHPVDFKLPVGPMFSHVEGLVRTPSGRTVQPNLIDNGDGTVTAQFQPTEPGLHELEITYNGQPIPGSPFRFYVEA-VGSGNVSAYGPGLSYGRAGEPAEFTLVTREAGAGGLSLSVEGPSKAEIQCHDNKNGTCSVSYLPLVPGEYTISIKFMERHIPGSPFTAHVGGETRRFNQVCVGTTSEMPLRITETDIYNLVATVRSPSGQEQPSSLKRLPNGHLGISFTPREIGEHYVNVFRNGRHIANSPFKIYVGEGEIGNASKVRIYGNGLHEGTANQNCQFTVDTRNAGYGSLSLSIEGPSKADIECHDNHDGTCLVTYRPTEPGTYIINVKYADQLVNGSPFVVHIGGEPSLRMMERITRQRELADVTHVGSQCELNLKIPGISLRDLTATVTSPSGVTQRCDVMPIDDVNYTIRFVPQEMGVHTVSVRHRGSHIPGSPFQFTVGAITDGGAHKVHAAGPGLQHGLTYSPNEFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKDGSCGISYRVTEPGEYQCSVRFNDENIPGSPFRVIINEAMERTFYSP---------ELRQLSVAAVQDRGLQIGRPTAFTVNYTGMS-GTLRAYAVSPSGVQIPAYVHQVDVDQHGVRFTPQENGPHLVHVLMDERPIPGSPFRIIVGQEDFGLVTASGEGLTHGRVGEKNRFFVNTTQAGSGALSVTVDGPSKVKLNCTERPDGYEFTYLPLAPGDYMINIRHGDQRHIIGSPFKAYVTGDAVQDIYTADTTHVVVETGSRLAAGPQRLVTEPRPDKVICTGSGLHQAFLNQTNTFNVNATQAGHDVLYVGVSGPVVACEEVNVKHLGLGQYAVNYLVRDRGQHLIMIKWGDQHVPGSPFAVNV 2497 HSP 2 Score: 124.02 bits (310), Expect = 5.201e-24 Identity = 129/498 (25.90%), Postives = 207/498 (41.57%), Query Frame = 2 Query: 1037 NLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA-GDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVI-------LDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNS----DAKQAYATGRGIQPEGVRVRDVAEFQV-HTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIV-SKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDE-NIPKSPYMAQIQLDT-------------------------KLFD---PLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIP---VQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVI 2392 +L V +P G + C++ P ++ Y+ ++P G + + ++ S IP SPF+ V G KV A+GPG++ F+++T EAG G + I +D + RKD I Y E G + +V F I SPF V+++ + + +Q +Q G+++ F V +T +G L P + +V + + PQ GP++V + PI SPF + V + A G GLT G V K FF T +GAL ++ GPS+ K++C + DG TY P PG+Y ++I D+ +I SP+ A + D +L P KV G GL N+ F VN AG V+G + V ++ G Y+ Y + G+H +++ +G+ ++P SPF VNV+ Sbjct: 2026 DLTATVTSPSGVTQRCDVM--PIDDVNYTIRFVPQEMGVHTVSVRHRGSHIPGSPFQFTVGAITDGGAHKVHAAGPGLQ--HGLTYSPNEFSIYTREAGAGGLSIAIEGPSKAEIDFEDRKD-----------GSCGISYRVTEPGEYQCSVRFNDENIPGSPFRVIINEAMERTFYSPELRQLSVAA--VQDRGLQIGRPTAFTVNYTGMSG--TLRAYAVSPSGVQIPAYVHQVDVDQHGVRFTPQENGPHLVHVLMDERPIPGSPFRIIVGQEDFGLVTASGEGLTHGRVGEKNRFFVNTTQAGSGALSVTVDGPSKVKLNCTERPDGY-EFTYLPLAPGDYMINIRHGDQRHIIGSPFKAYVTGDAVQDIYTADTTHVVVETGSRLAAGPQRLVTEPRPDKVICTGSGLHQAF-LNQTNTFNVNATQAGH----DVLYVGVSGPVVACEEVNVKHLGLGQYAVNYLVRDRGQHLIMIKWGDQHVPGSPFAVNVV 2498
BLAST of Filamin vs. TrEMBL
Match: A0A5J4NU72 (Filamin OS=Paragonimus westermani OX=34504 GN=DEA37_0004303 PE=4 SV=1) HSP 1 Score: 2806.16 bits (7273), Expect = 0.000e+0 Identity = 1418/2540 (55.83%), Postives = 1805/2540 (71.06%), Query Frame = 2 Query: 170 LAERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSNFRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSK----------------------------------TSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILT----PFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKST-PGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAF---------QPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXX-----XXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKG--PSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 +AERELAEDA+WK+IQKNTFTRWAN+HLKP N+ ++DLQYD ADGLKLI LV+ LSG F+H +++P+FRTQKLENVTMVLRFLEE+EGLRLVNIDS+DI D R KLILGLIWTLILHYSIT+PLWEGE GQG+GP+PKQRLL W+N+K+ +PVKNFTTDWNDG AIGALVDACAPGLCP+W +W+PKQ L+NA+EA++ AE+ L+V LI+P E+INP+VDEKAMMTYLSQFP+A+L APL PK+ VRAYGPGL+ GNT+GNPA FT+DTF+AG+G +++IVLNPKGQ+EPCEI + +++ YSC+Y+PT EGEYR+IIKFA EI NSPFKV V+ A GD SK +ASGPGIEP GN+ GRRTFFN+FTA AGPG+VDCVILD GR+D++KP ITKQ E+ +L+EYT K+EGLHSVNVFFAG QI +SPFGVMV+ K DAKQAYATGRGIQP+G+RV+D+A+F+VHTEDAG L V V P C +K L++CSY PQR G + V ++YG + I LSPFNVDV PYKES+I+AFGPGL+GG+V+KPA F VETNGETGALGFSI+GPSEA+IDC DNGDGSA V YWPTVPGEYAVHILC+DENIPKSP+M I D DP +V +GPG++ +G +P +F V+ ++AG P+ + EC D G+ + +++RDN DGTY+C YTPK+P KHT++VSYG VN+P SPF+V+V E ++V+GPG+E T+F+VDCK AG G++GISV DE RDV + T D DGTF + YT T GP YTI +FF+ E+P+SPF+VP++ + D K + NL+ P+G+ EF+++T P SK RP ++V SP+G RVP + E+ +GF FTPTV GPHTV ++ G P+ SP++ A+ ETP+ ++P P+ +A + + P + E A L V A+G+GL + PA F IDS + PPAPL VTIEGP EAKI+Y DNGDGTC V YLP EPG Y+VNVLY D HIK SPF V + P + DV++V AYGPGL PTGV K+SF+KFTV+AKP+D G+G+VKAI+ NP QR+ C V NN DGT+ CSYSP +G H I++TYDG PV SP+ V V G DPSR+ AYGPGLE G+T + Q+FTVDL+GAGQG LGL++EGPADAQIQC DNKDGTC+V+YLP + GSYDV +KFN+ +IPGSPF VPI D VD S+V+CYGPGLE G+R P+ FTVDAS+AG+AP+ V +D +S PA ++P++ PG++DVTY+P G C+IEV V SPF Q+VL + EP++V VTGEGV P R + P+ F ++TRDAG DLEL V+ P + + L+V +HGDGT+TC Y+ V G +TV+V +G + + SPF+VPV + + C+IE + VPVG+ I +NT AG G ++ + V P G I+ G V Y P G Y V++ F E +PNG Q A QP ER H T + T Y VDFK PVGP F V +V PS R P LI+NGDGT+T Q+QP+E GLHELE+ YNGQPI GSPF+FYV++ + SG VTAYGPGLSYGR A FT+VTK+AGAGGLSL+VEGPSKAEIQC DNKNGTC VSYLPLAPGDY I IKFM++HI GSPFTA I GE ++ +Q+CVGTTS++PLRI+ETDI NL A V SP+G+E+ TLKRL NG+LGISFTP+E+G+H VNV R+GRHI NSPFKI+VGE+EIGNAS+V++YG+GL +G N+ CQF VDTRNAGYG LSLSIEGPSK +IECHDNHDGTCLVTY+PTEPGTYIINVKYAD V GSP+ V++GG PS + ERI R ++ A+V+ +G+ CELNL IPG + R+ TA+V SPSG + C++IA+ D ++I+F+P+E+GVHTVSV+ H+ GSPFQFTVG + DGG HKV G G++ GL N F+IYTREAGAG LS+AIEGPSKAEIDF+D KDGSCG++YRV EPG+Y CS++FNDEH+PGSPF + I+E ++ P + R +S+A++QD+G IG F +NY G+T G + AYV++PS + A I ++D +Q++V F P ENG H VHVL++ PIPGSPFRV+VG+ VT +GEG+ HG G N FFV+T+ AG+GAL+VT+DGPSKVQLNC E GY+F+Y+P APG+Y I+I++G HI+GSPF ++G+ + T + +T ++ Q+ S+P V C G GL+ A + + N F V+A AG DVLYVGVSGPV CEEVNIKHLG+ ++ VNY V+++G+HL+MV+WG+ VPGSPF I V Sbjct: 83 MAERELAEDAEWKLIQKNTFTRWANEHLKPKNMFVEDLQYDFADGLKLIGLVEALSGQQFKHVNRKPSFRTQKLENVTMVLRFLEENEGLRLVNIDSTDIVDSRSKLILGLIWTLILHYSITIPLWEGE---VDHGQGQGPTPKQRLLSWLNNKLVERPVKNFTTDWNDGIAIGALVDACAPGLCPDWRKWEPKQNLRNAREAMDAAEQWLDVPQLIRPEEIINPRVDEKAMMTYLSQFPSAKLKEGAPLRPKSTPELVRAYGPGLQPHGNTVGNPARFTIDTFSAGRGQVEVIVLNPKGQREPCEILSNNDRQQTYSCAYVPTQEGEYRVIIKFATKEILNSPFKVMVEGAIGDASKASASGPGIEPQGNQAGRRTFFNIFTAAAGPGNVDCVILDPHGRRDAIKPVITKQGEDNYLVEYTPKDEGLHSVNVFFAGQQIPNSPFGVMVAPKPVAQPPIQPPAPIIPSQEEPIQAAISQRKMSAPRRPACDAKQAYATGRGIQPQGIRVKDLADFKVHTEDAGEGPLEVTVISPDGREIPCTTRKTGAYLFDCSYNPQRAGLHQVHVRYGGDHIMLSPFNVDVGPYKESRIRAFGPGLSGGVVNKPAVFVVETNGETGALGFSIEGPSEARIDCTDNGDGSATVAYWPTVPGEYAVHILCNDENIPKSPFMVPIDPDMGKCDPERVKVHGPGVMPTGNVAGQPTEFTVDIRDAGGPAPLTVECRDNEGEPVALKVRDNGDGTYTCSYTPKVPRKHTILVSYGTVNVPRSPFRVDVAEPSQPGRVRVFGPGVESVVRGEPTHFIVDCKQAGQGNVGISVTDEMGRDVAMDTQDMRDGTFRVAYTANTPGPNYTIHVFFNNQEVPRSPFRVPVKPNVDMSKILVENLSPNIPVGKPTEFDVITAGAGPPSNSKPRPNVVVTSPSGMRVPCTMAESVDGFTPSFTPTVTGPHTVAIDVGGIPVKGSPFRTHAS----------PETPI-------------HEPVYPMSNAG---------------QQHAAAMAPMSAL--------EAAGL----VRAFGDGLYHATSGRPAHFTIDSRDAPPAPLSVTIEGPAEAKINYNDNGDGTCGVEYLPTEPGPYVVNVLYKDVHIKGSPFPVRVAPPGREHV---DVSRVHAYGPGLQPTGVLKESFAKFTVDAKPVDPQGRGLVKAIVVNPHKQRTACLVQNNGDGTWKCSYSPIDEGLHHIEVTYDGAPVQGSPFPVNVAPGCDPSRVCAYGPGLEGGLTHELQRFTVDLDGAGQGALGLALEGPADAQIQCHDNKDGTCTVEYLPTRAGSYDVFVKFNDMNIPGSPFQVPIRDRVDPSRVRCYGPGLEPRGARAQQPATFTVDASQAGDAPVHVATVDRLGRST-PAHVVPRAAQPGVYDVTYVPNTEGPCQIEVRQGPSHVARSPFTQHVLPAFEPQRVRVTGEGVHPSRPLGLPATQPTSFHVDTRDAGIGDLELSVSDPEAQPLQLEVVDHGDGTYTCHYRPMVVGRHTVRVKFGGQEITESPFLVPVAPSGRADLCHIESGNDSRVPVGQECVITLNTSQAGIGQVTCRIVTPSGATADVEIQEAPNGRVHVYYTPPIRGDYLVEVRFGGELVPNGRFNQRAVTADELMADTQPPTYIQEERVQHMTTQSLHSSTMVTGYHPVDFKLPVGPTFSQVEGLVRTPSGRTMQPTLIDNGDGTVTAQFQPNEPGLHELEITYNGQPIPGSPFRFYVEA-VGSGVVTAYGPGLSYGRAGELADFTLVTKEAGAGGLSLSVEGPSKAEIQCNDNKNGTCSVSYLPLAPGDYTISIKFMERHIPGSPFTAHIGGETRRLNQVCVGTTSEMPLRITETDIYNLVATVRSPSGQEQPSTLKRLPNGHLGISFTPREIGDHYVNVFRNGRHIANSPFKIYVGESEIGNASKVRVYGNGLREGTANQNCQFTVDTRNAGYGSLSLSIEGPSKADIECHDNHDGTCLVTYRPTEPGTYIINVKYADQLVQGSPYVVHVGGEPSLRMMERITRQRELADVTHVGSQCELNLKIPGVSLRDLTANVTSPSGVTQRCDVIAVDDVNYTIKFVPQEMGVHTVSVRHRGSHIAGSPFQFTVGAITDGGAHKVRAAGQGLQHGLTYAPNDFSIYTREAGAGGLSVAIEGPSKAEIDFEDRKDGSCGISYRVTEPGEYQCSVRFNDEHIPGSPFQVTINETMERTFYSP---------ELRQLSVASIQDRGLQIGRSTAFTVNYSGMT-GRMRAYVVAPSGVQTEAYIHQVDVDQHAVRFTPQENGPHLVHVLMDERPIPGSPFRVIVGQDDFGLVTATGEGLSHGRVGERNRFFVNTTQAGSGALSVTVDGPSKVQLNCTERPDGYDFSYLPMAPGEYLINIRHGDQQHIVGSPFKAFVTGDAVHDVFTADSTHVVVETGGRLATGPQRSVTESRPNRVICTGSGLQQAYLNQTNTFTVNATQAGHDVLYVGVSGPVVACEEVNIKHLGSGQYAVNYVVRDRGQHLIMVKWGDQHVPGSPFVINV 2554 HSP 2 Score: 118.242 bits (295), Expect = 2.809e-22 Identity = 125/497 (25.15%), Postives = 203/497 (40.85%), Query Frame = 2 Query: 1037 NLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAA-GDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVI-------LDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNS----DAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIV-SKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHIL-CDDENIPKSPYMAQIQLDT--KLFD--------------------------PLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIP---VQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVI 2392 +L V +P G + C++ ++ Y+ ++P G + + ++ S I SPF+ V G KV A+G G++ F+++T EAG G + I +D + RKD I Y E G + +V F I SPF V ++ + + +Q IQ G+++ F V+ + V P + I +V + + PQ GP++V + PI SPF V V + A G GL+ G V + FF T +GAL ++ GPS+ +++C + DG + +Y P PGEY ++I D ++I SP+ A + D +F P +V G GL N+ F VN AG V+G + V I+ G Y+ Y + G+H ++V +G+ ++P SPF +NVI Sbjct: 2083 DLTANVTSPSGVTQRCDVIAV--DDVNYTIKFVPQEMGVHTVSVRHRGSHIAGSPFQFTVGAITDGGAHKVRAAGQGLQ--HGLTYAPNDFSIYTREAGAGGLSVAIEGPSKAEIDFEDRKD-----------GSCGISYRVTEPGEYQCSVRFNDEHIPGSPFQVTINETMERTFYSPELRQLSVAS--IQDRGLQIGRSTAFTVNYSGM-TGRMRAYVVAPSGVQTEAYIHQVDVDQHAVRFTPQENGPHLVHVLMDERPIPGSPFRVIVGQDDFGLVTATGEGLSHGRVGERNRFFVNTTQAGSGALSVTVDGPSKVQLNCTERPDGY-DFSYLPMAPGEYLINIRHGDQQHIVGSPFKAFVTGDAVHDVFTADSTHVVVETGGRLATGPQRSVTESRPNRVICTGSGLQQAY-LNQTNTFTVNATQAGH----DVLYVGVSGPVVACEEVNIKHLGSGQYAVNYVVRDRGQHLIMVKWGDQHVPGSPFVINVI 2555
BLAST of Filamin vs. Ensembl Cavefish
Match: flna (filamin A, alpha (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-030131-2145]) HSP 1 Score: 1858.19 bits (4812), Expect = 0.000e+0 Identity = 1070/2554 (41.90%), Postives = 1522/2554 (59.59%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYK-ESKIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQ-LDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE----TYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNE---FEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETET--PLLISADYAIDNKAYNKPSIPVQSAKLT-PVER---SNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEK-------------AELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILN-EVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTT----HHYTTEQSKPI---------------IRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXX---------XXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLT--QTVHMISGSTQKGP----SKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK N I +LQ DL+DGL+LI L++ LS FR ++RP FR +LENV++ L FL+ E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+W+ E+ + D + K +PKQRLLGWI +K+P P+ NF+ DW G A+GALVD+CAPGLCP+W WD + + NA+EA+ A+E L V +I P E+++P VDE ++MTYLSQFP A+L APL PK N + RAYGPG+E GN + A FTV+T +AG+G + + V +P G +E ++ + +K YS YIP + G +++ + FA I SPF+V+V A GD SKVTA GPG+E VGN + T+F+V+TA AG G V+ VI+D G+KD+V+ +I + + + Y +EG H + + FAG QI SP+ V V + S A GRG+QP+G+R+++ AEF+V+T+ AG +L V + GP E C+ K + +Y Y P PG Y++ I +G I SPF V V +++A+GPGL G+V K A F VE G+ G LGFS++GPS AKI+C D GDGS +V YWPT PGEYAVH+LC +E+I SP+MA+I+ + F P KV AYGPGL SG+S KPA+F V+ K G + +K + D G + VQ++DN +GTYSC YTP+ P KHTV+VS+G VN PESPF++N+ + +KV GPG+ AKT ++ TYF VDC AG GDI I + +G T + F++ IP +P ++ ++ +D K K + +LN+ F + T G K + + P NN + +TP G V V G+PI +P+ V ++ + + + D I K+ AK+T P + V+ +P + F P ++ Y V+ T + A V G GL + F++D T PA L + I + EA++ DNGDGT ++ Y+P PG+Y + + Y + + + P + + P ++S V +GPG+ GVF+++ ++FTV+A+ + G +K + NP + + + DGTY Y+P +G H +++ YD PV SP+ VPV +G DP+R+R +GPGL+ G+T +P KFTV+ GAG GGLGL++EGP++A++ C DNKDG+CSV+Y+P +PG+Y+++I + + I GSPF+VP+ D VD +KVKC G G+ N R P FTVDASKAG APL+V V V+PA+++ V+Y+P G I VLY + ++P SP+ VL + + KV +G G+ + +P FTI+ +DAGE L + +T P + ++ ++ DGT+ Y D+ G YT+ + YG +P SP+ + +C + G + + +G+ I V+ + AG G ++ P G V + G + Y + G Y + + F E+IPN + A + + + T + Y +P +R V+ F G V VR PS + P + +N DGT+TV+Y P+E+GLHE+++ Y+G I GSP +FYVD + SG VTAYGPGL +G + A FT+ TKDAG GGLSLA+EGPSKA+I C+DN++GTC VSYLP+ PGDY+I +K+ DKHI GSP+ AKI G+ R S + VG+ +D+PL I E D++ L A + +P+GREE C LK L+NG++G+SF PKE+GEHLVN+ ++GRHIP+SP + + ++EI +ASRV++ G GL++ E +F++DTR+AGYGGLSLSIEGPSKV+I D DGTC VTY PTEPG YIIN+K+AD +VPGS F V + G + E I R + AA V+ +G+ C+L+L IP + + TA V SPSG EI+ +N + IRF+P E+GVHTVSVK +HV GSPFQFTVGPL +GG HKV G G+ER A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGS GV+Y V EPGDY SIKFNDE++P SPF++ P +S S +D+R +++A+LQ+ G + A+F ++ +G G I A V SPS + +++ID ++Y+V F+P ENG++ + V N S IPGSPF++ VGE + G G+ G+TG EF V+TS+AG GAL VTIDGPSKV+++CQE GY TY P APG+Y ISIKYGG HI+GSPF I+G+ S+ S+ ET S+ ++ S Q P S V +G GL IG++N F VD AG ++L VGV GP PCEE+ +KHLGN + V+Y ++EKG ++L+V+WG+ +PGSPF I V Sbjct: 33 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIANLQTDLSDGLRLIGLLEVLSQKKMFRKYNQRPTFRQMQLENVSVALEFLDR-ENIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWD-EEEDTDDAKQK--TPKQRLLGWIQNKLPELPITNFSRDWQSGKALGALVDSCAPGLCPDWDSWDQTKPVDNAREAMQQADEWLGVPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPGIEPTGNVVMKKAVFTVETISAGQGEVLVYVEDPAGHREEAKVTANNDKNRTYSVFYIPKVTGMHKVTVLFAGLHISKSPFEVDVGMAQGDSSKVTAQGPGLEAVGNIANKTTYFDVYTAGAGVGEVEVVIMDPSGKKDTVECQIEDKGNSSYRCTYKPTQEGQHIIYITFAGGQISKSPYTVSVGEACNPS---LCVAKGRGLQPKGLRIKETAEFKVYTKGAGTGELKVTIKGPKGLEEPCKKKDLGDGVYSFEYYPTTPGNYIITITWGGQHIPRSPFEVKVGTEAGAQQVRAWGPGLESGVVGKSADFVVEAVGDDVGTLGFSVEGPSPAKIECDDKGDGSCDVRYWPTEPGEYAVHVLCKNEDIQHSPFMAEIKPAPDRDFYPDKVKAYGPGLQSSGLSVGKPAEFTVDAKLGGK-APLKIQAQDRDGNPVDVQVKDNGNGTYSCSYTPRKPLKHTVMVSWGGVNTPESPFRMNIGAGCHPNKVKVSGPGV--AKTGLKAFEPTYFTVDCAEAGQGDISIGI-------------KSGSYTI---------------MVLFADQAIPMTPIRIKVDPSHDASKVKAEGPGLSRTGVELNKPTHFTVNTKGAG-KAKLDAQFTGPTKGEAVRDFDIVNNHDNTYTVKYTPVQQGNMGVNVTYGGDPIPKTPFAVAVAPSLDLSKVKVAGLGDKMTVGKDQDITVKSKGAGGQGKVGAKVTGPAGKPVPCKVEPGLSPETSQVRFIPRDKGPYEVELTYDGVPIPGSPFPVEAVAPTDPSKVRCSGPGLERAKVGETGQFVVDCTNAGPAELTIEIISDNGTEAEVHIQDNGDGTYTITYIPLYPGAYTLTIRYGGQDVPNFPARLHVEPAVETSG-------VKVFGPGVEGKGVFREATTEFTVDARALTKTGGKHIKTCVNNPSGNCTEALIRDQGDGTYKVEYTPYEEGPHSVEVAYDDSPVPNSPFRVPVTEGCDPARVRVHGPGLKAGLTNKPNKFTVETRGAGTGGLGLAMEGPSEAKMSCTDNKDGSCSVEYIPYEPGTYNLNITYGGQPITGSPFSVPVQDTVDPTKVKCQGQGIGTN-VRANIPQVFTVDASKAGMAPLQVRV-QGPKGVVEPAEVVDNGDQ-THTVSYVPTREGPYSINVLYADEEIPRSPYKVKVLPTHDASKVRASGPGLNTTG---VPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKANIRDNQDGTYLVSYVPDMTGRYTILIKYGGDEIPYSPYRIRALPTGDASKCTVTGAGVGPTIQIGEQTVITVDAKAAGKGKVTCTVCTPDGAEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEHIPNSPFQVMALEGASPEQLMQQTQVPQYAYAPNMGQPWATDRPMGMNGLDVAGLRPFDLVIPFTIQKGEVTGEVR----MPSGKVARPEIADNKDGTVTVKYAPTEAGLHEMDIKYDGIHIPGSPLQFYVD-YVNSGHVTAYGPGLIHGMVNKPAVFTVNTKDAGEGGLSLAIEGPSKADISCVDNQDGTCTVSYLPVLPGDYNILVKYNDKHIPGSPYVAKITGDDSMRMSHLKVGSAADIPLDIGELDLSQLTASLTTPSGREEPCLLKMLRNGHVGVSFVPKEIGEHLVNIKKNGRHIPSSPISVMINQSEIADASRVRVSGQGLSEARTFEPAEFIIDTRDAGYGGLSLSIEGPSKVDINTEDQEDGTCKVTYCPTEPGNYIINIKFADQHVPGSAFTVKVTG--EGRMKESITRKRRAASVANVGSQCDLSLKIPEISIADMTAQVTSPSGKVHKAEIMEGENNTYCIRFVPTEMGVHTVSVKYQGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEIAFEDRKDGSSGVSYIVQEPGDYEVSIKFNDENIPDSPFVV-----PVASPS----------DDARRLTVASLQESGLKVNQPASFAVSLNG-AKGVIDAKVHSPSGALEECCVTEIDEDKYAVRFIPRENGLYLIDVKFNGSHIPGSPFKIRVGEAGQAGDPGMVSAYGAGLEGGNTGSPCEFIVNTSSAGPGALAVTIDGPSKVKMDCQECPEGYKVTYTPMAPGNYLISIKYGGPYHIVGSPFKARITGSRLVSSHSMHETSSVLVDPVTRSVTSSQQAAPGWASSDASRVVAKGLGLTKGFIGQKNSFSVDCSKAGRNMLLVGVDGPKVPCEEILVKHLGNRLYNVSYQLKEKGEYILVVKWGDDHIPGSPFHITV 2511
BLAST of Filamin vs. Ensembl Cavefish
Match: flncb (filamin C, gamma b (actin binding protein 280) [Source:ZFIN;Acc:ZDB-GENE-041008-175]) HSP 1 Score: 1397.88 bits (3617), Expect = 0.000e+0 Identity = 891/2276 (39.15%), Postives = 1271/2276 (55.84%), Query Frame = 2 Query: 992 NPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE----SKIKAFGPGL--TGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDC--VDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPS-TVKAECF-DVTGQT---IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIE----TYFVVDCKLAGSGDIGI----SVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQE--TNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV---IATDRVNTKEYPETETPLLIS--ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILN-EVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPG-YNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXX---------XXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMIS------GSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 P F + T AG G++ +I+++ +G+++ EI + + C+Y P +EG + I + FA +IP SPF V++ A+ +P+ A G G++P G V F V+T AG G + +I KG + VK + + + +Y G ++V + + G I SPF V+VS ++ ++ A G G+ E V A+F V LG ++ GP ++ +C K C + Y P PG Y V + + I SPF + P K+K +GPGL TG IV+KPA F ++ G G L + ID DNGD + Y PT P ++ + I + N+P SP+ I + P V YGPG+ SG+ N+P F V+ AG ++ +C V G I I N++ T++ +YTP G++T++V + + IP SPF++ V + +A +K GPG+ KT +E T+F V K AG + ++ E + D ++ DN D ++T++YT G T +A IP+SPF + + D K K+ LN +G+ EF I T G + + ++ + SP+ +P K++ N + P GP+ V + GNP+ SP+ V + D + Y ++ A +AID K + + P E + ++ N + S ++ P E Y + + ++ VTA G GL +G N ASF +D ++ A L + I + +A++ +N DGT S+ Y+P G Y + + Y + P V + P D + V +GPG+ P GV ++ + F V+ + + G +K I NP + + + DGTY Y+ DG H I++ YD V V KSP+ V V +G DPSR+RAYGPGLEEG+ +P +FTV+ GAG GGLGL+IEGP++A++ C DNKDG+CSV+Y+P PG YDV+I F IPGSPF VP+ ++VD SKV+C GPGL NG R P FTVD SKAG APL+V ++ T + +P I G V Y P G + V Y + +VP SPF L + + KV +G G+ + +P FTI+ RDAGE L + + P + ++ ++ DGT+T Y D+ G YT+ + YG +P SP+ + +C + G L + +G+ I V+ + AG G ++ K P G + + G + Y + G Y + + F E+IPN + + RT + + K I E V PS + P + +N DGT+TV+Y P+E GLHE+++ Y+G I GSP +FYVD+ I SG VTAYGPGLS+G + + FTIVTKDAG GGLSLAVEGPSKAEI C DNK+GTC VSYLP APGDY+I +KF DKHI GSPFTAKI G+ R SQ+ VGT +DV L+I+ETD+++L A + +P+G EE C LKRL N ++GISFTPKEVGEH+V+V ++G+H+ NSPFKI VG++EIG+AS+VK++G GL +G E +F+VDTR+AGYGGL LSIEGPSKV+I C D DGTC VTY PTEPGTYIIN+K+AD +VPGSPF V + G E I R + A ++ +G+ C+LNL IPG + R TA V SP G + EII D+ +S+RF+P+E+G HTV+VK +HV GSPFQFTVGPL +GG HKV G+G++RG+A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGSCGV Y V EPGDY SIKFNDEH+P SPF++ I + +D+R +++ +LQ+ G + +A+F + +G G I A V +PS + I+++DN+++++ F+P ENG+H++ V N S IPGSPF++ V G V+ G G+ G TG ++F V+T NAG+GAL+VTIDGPSKV+++CQE GY TY P APG Y ISIKYGG HI+GSPF +SG S+ ET S L +TV S S K S V G GL A IG++N F VD AG ++L VGV GP PCEEV +KH+GN + V Y V+EKG ++L+V+WG+ VPGSPF + VP Sbjct: 359 QPTYFDIYTAGAGAGDVGVIIVDSQGRRDTVEIILENKGDSVFRCTYGPVLEGPHVIYVTFAGQQIPRSPFTVHISEAS-NPNACRAIGRGLQPKGVRVKEVADFKVYTRGAGSGDLRVLIKGPKGGDEPVK--VHDLGDGVYECDYYPIFTGKYTVIITWGGHAIPRSPFEVVVSE---DAGPQKVRAWGPGL--ETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSC--DVLYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVKCYGPGLEPTGCIVNKPAEFTIDARGAGRGQLKIYAQDSEGYPIDIQITDNGDSTFFCVYIPTKPIKHTIIITWGEVNVPNSPFRVTIGEGSH---PENVKVYGPGVEKSGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFADQEIPISPFRIKVDPSHDANKVKAEGPGL--CKTGVEVGKPTHFTVYTKGAGKATPEVHFTGALKGEAVSDFEII--DNHDYSYTVRYTAIQQGNTSISVCHGGDA-IPKSPFVINVAPPLDLSKIKVQGLNTKVDVGKDEEFIINTRGAGGQGKVDVKITSPSRRPIPCKVESGTANEVHTVKYIPPEEGPYKVDINYDGNPVPGSPFTVEGVMPPDPSKVRAYGPGLKGGIVGKPAPFAIDTKGAGTGGLGLTVEG--PCE-AKIECQDNGDGSCSVSYLPTEPGEYAINILFADAHIPGSPFKAMVQSVFDPSKVTASGPGLERGKVNEAASFTVDCSKAGEAELTIEIISDSGAQAEVHVQNNSDGTYSITYIPPFHGMYTITINYGGHAVPKFPARVQVDPAV-------DTSGVKVFGPGVEPRGVLREVTTHFIVDTRAHNKTGGNHIKTRIVNPSGSNTDAYITDKGDGTYRVEYTAYEDGVHLIEVLYDEVSVPKSPFRVSVTEGCDPSRVRAYGPGLEEGLVNKPNRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCSVEYIPFTPGDYDVNITFGGLPIPGSPFRVPVRELVDPSKVRCSGPGL-GNGVRAHVPQTFTVDCSKAGLAPLEV-LLYGPTGTTEPVSITDNGD-GTHTVIYTPAKDGPYTVCVKYADQEVPRSPFKIKALPAHDASKVRASGPGLN---ASGVPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNRDGTYTVSYVPDMTGRYTITIKYGGDEIPYSPYRIHALPSGDASKCLVTGSGLGPTIQIGEETVITVDAKAAGKGKVTCKVSTPDGAELDVDVVENSDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPF----------HVVVRTFLSFDLQYRKLCIMGE--------------------VRMPSGKTARPHITDNKDGTVTVKYAPTEKGLHEMDIKYDGNHIPGSPLQFYVDA-INSGHVTAYGPGLSHGMVNKPSIFTIVTKDAGEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDDKHIPGSPFTAKITGDDSMRTSQLNVGTATDVSLKITETDLSSLTASIRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVKKNGKHVTNSPFKIMVGQSEIGDASKVKVFGKGLVEGHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCEDVEDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKVLG--EGRKKESITRRRQAPSIASVGSTCDLNLKIPGETSTREMTAQVTSPGGKTDDAEIIEGEDSTYSVRFVPQEMGPHTVNVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLDRGVAGVPAEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVAYVVQEPGDYEVSIKFNDEHIPDSPFIVPI---------------ATLSDDARRLTVTSLQEMGLKVNHEASFAVQLNG-ARGVIDAKVHTPSGAVEECYITELDNDKHAIRFIPRENGVHSIDVRFNGSHIPGSPFKIRVGEPGQVGDPGMVSAFGPGLEGGTTGVPSDFIVNTCNAGSGALSVTIDGPSKVKMDCQECPEGYKVTYTPMAPGSYLISIKYGGPQHIVGSPFKAKVSGARLSGGHSLHETSSVLVETVTKTSSVAGSFASLPKFSSDASKVVSRGTGLSKAFIGQKNTFTVDCSKAGTNMLMVGVHGPKTPCEEVYVKHMGNRMYNVTYTVKEKGDYILIVKWGDEMVPGSPFHVTVP 2551 HSP 2 Score: 1081.63 bits (2796), Expect = 0.000e+0 Identity = 839/2578 (32.54%), Postives = 1234/2578 (47.87%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKT-NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNV----DVAPYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVL--------DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINN---LNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNN---GFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV----------IATDRVNTKEYPETETPLLISADYA-----IDNK--AYNKPSIPVQSAKLTPVERSNVKTF---SNPNKQRSNFEPNEEIIYPVQRTNEKAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQ-PQKFTVDLEGAGQGG---LGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF--------TAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGS---LSIAIEGPSKAEIDFQ--DNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPF------------RXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENE---SGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK N I DLQ DL+DGLKLI L++ LS +R H RPNFR KLENV++ L FLE E ++LV+IDS I D LKLILGLIWTLILHYSI+MP+WE ED D K +PKQRLLGWI +K+P P+ NF DW DG A+GALVD CAPGLCP+W WDP Q ++NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L APL KT + R +AYGPG+E GN + PA F V+T AG G + + + +P+G E + + +K +YS Y+P +EG +++ + FA +I +SPF VNV A GDP+KV + T+F+++TA AG G V +I+D++GR+D+V+ + + ++ F Y EG H + V FAG QI SPF V + S+ SN +A A GRG+QP+GVRV++VA+F+V+T AG DL V + GP E ++ + +YEC Y P G Y V I +G + I SPF V D P K++A+GPGL G+V K A F VE G E G LGFSI+GPS+AKI+C D GDGS +V YWPT PG+YAVH++CDDE+I SP+MA I P KV YGPGL +G NKPA+F ++ + AG +K D G I +QI DN D T+ C Y P P KHT+I+++G VN+P SPF+V + E + N+KVYGPG+E++ K N TYF VDC AG GD+ I + E D ++ +DN T YTI + F++ EIP SPF++ ++ +D K K +G+ F + T G K PE+ + +N + +T G +++V G+ I SP+ + I +NTK + +I+ A +D K + ++ IP + T E VK P K N++ N PV + E P V AYG GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDG+CSV+YLP EPG Y +N+L+ D HI SPF + ++ D +KVTA GPGL V + + FTV+ G+ + I + ++ V NN DGTYS +Y P G + I I Y G V K P V V D S ++ +GPG+E G+ ++ F VD + G + I P+ + + D DGT V+Y + G + + + ++E +P SPF V + + D S+V+ YGPGLE V P++FTV+ AG L + + + + + G V YIP G+ ++ + + + +PGSPF V +P KV +G G+ G+ + VP FT++ AG + LE+++ GP + + + ++GDGT T Y G YTV V Y ++ VP SPF + + GP LN VP V ++ ++AG+G+L+ + + P G +I + R G TVSYVP G Y + + + + IP R +A S + + T P I+ V V V+ P + ++ N DGT + Y E G + + + + G+ I SPF V + LS+ D+ + + V PS A DNK+GT V Y P G + + IK+ HI GSP + + S V S + + L+ V P+ E SC K ++G +S+ P G++ + V +HIP SPF + ++ S+ LN G + + +T L+ SI PS E C + H G +++ P E G ++++VK +V SPF + +G ++ + + E V E + S+ PS CE + D + + P E G + +++K ++HV GSPF V + G K I +A+ + + + G S ++ + P D + + +D + V + E G + ++K+ +HVPGSPF + P + + D+G G A F I G +S V PS E S + V +V E G + V + N+ IP SPF R+ V + G ++H + F N G + + PS C E + ++P G ++I +++ G +HI GSPF + + G Q D P V G GL+ G ++FIV+ AG L V + GP + C+E ++V Y G +L+ +++G + GSPF+ V Sbjct: 5 EKDLAEDAPWKKIQQNTFTRWCNEHLKCMNKKIGDLQRDLSDGLKLIGLLEVLSQKKMYRKYHARPNFRQMKLENVSVALEFLER-EHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDED----DEDAKKLTPKQRLLGWIQNKVPQLPINNFHRDWRDGKALGALVDNCAPGLCPDWEMWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRSKTLHPKRAKAYGPGIEPRGNMVMRPAEFVVETVEAGLGEVLVYIEDPEGHTEEARVIPNNDKNRSYSVVYLPKVEGLHKVKVLFAGQDINHSPFLVNVSKALGDPNKV---------------QPTYFDIYTAGAGAGDVGVIIVDSQGRRDTVEIILENKGDSVFRCTYGPVLEGPHVIYVTFAGQQIPRSPFTVHI-SEASNPNA--CRAIGRGLQPKGVRVKEVADFKVYTRGAGSGDLRVLIKGPKGGDEPVKVHDLGDGVYECDYYPIFTGKYTVIITWGGHAIPRSPFEVVVSEDAGP---QKVRAWGPGLETGMVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVLYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVKCYGPGLEPTGCIVNKPAEFTIDARGAGR-GQLKIYAQDSEGYPIDIQITDNGDSTFFCVYIPTKPIKHTIIITWGEVNVPNSPFRVTIGEGSHPENVKVYGPGVEKSGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTV---KYTPPGAGRYTIMVLFADQEIPISPFRIKVDPSHDANKVKAEGPGLCKTGVEVGKPTHFTVYTKGAG-KATPEVHFTGALKGEAVSDFEIIDNHDYSYTVRYTAIQQGNTSISVCHGGDAIPKSPFVINVAPPLDLSKIKVQGLNTKVDVGKDEEFIINTRGAGGQGKVDVKITSPSRRPIPCKVESGTANEVHTVKYIPPEEGPYKVDINYDGN-----PVPGSPFTVEGVMPPDPSKVRAYGPGLKGGIVGKPAPFAIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCSVSYLPTEPGEYAINILFADAHIPGSPFKAMV-------QSVFDPSKVTASGPGLERGKV--NEAASFTVDCSKA---GEAELTIEIISDSGAQAEVHVQNNSDGTYSITYIPPFHGMYTITINYGGHAVPKFPARVQVDPAVDTSGVKVFGPGVEPRGVLREVTTHFIVDTRAHNKTGGNHIKTRIVNPSGSNTDAYITDKGDGTYRVEYTAYEDGVHLIEVLYDEVSVPKSPFRVSVTEGCDPSRVRAYGPGLEEG--LVNKPNRFTVETRGAGTGGLGLAIEGPSEAKMS----CKDNKDGSCSVEYIPFTPGDYDVNITFGGLPIPGSPFRVPVRELVDPSKVRCSGPGL----GNGVRAHVPQTFTVDCSKAGLAPLEVLLYGPTGTTEPVSITDNGDGTHTVIYTPAKDGPYTVCVKYADQEVPRSPFKIKALPAHDASKVRASGPGLNASGVPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNRDGTYTVSYVPDMTGRYTITIKYGGDEIPYSPYRIHALP-----SGDASKCLVTGSGLGPTIQIGEETVITVDAKAAGKGKVTCKVSTPDGAELDVDVVENSDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVVVRTF------------LSF---DLQYRKLCIMGE---------VRMPSGKTARPHITDNKDGTVTVKYAPTEKGLHEMDIKYDGNHIPGSPLQFYVDAINSGHVTAYGPGLSHGMVNKPSIFTIVTKDAGEGGLSLAVEGPSKAEISC--KDNKDGTCTVSYLPTAPGDYNIIVKFDDKHIPGSPFTAKITGDDSMRTSQ-------LNVGTATDVSLKITETD---LSSLTASIRAPSGNEEPCLLKRLPNRHIG---ISFTPKEVGEHVVSVKKNGKHVTNSPFKIMVGQSEIGDASKVKVFGKGLVE-GHTFEVAEFIVDTRSAGYGGLGLSIEGPSKVDINCEDV--EDGTCKVTYCPTEPGTYIINIKFADQHVPGSPFTVKV---LGEGRKKESITRRRQAPSIASVGSTCDLNLKIPGETSTREMTAQVTSPGGKTDDAEIIEGEDSTYSVRFVPQEMGPHTVNVKYRGQHVPGSPFQFTV--GPLGEGGA-----------HKVRAGGTGLDRGV-AGVPAEFSIWTREAGAGGLSIAVEGPSKAE--ISFEDRKDGSCGVAYVVQEPGDYEVSIKFNDEHIPDSPFIVPIATLSDDARRLTVTSLQEMGLKVNHEAS------FAVQLNGARGVIDAKVHTPSGAVEECYITELDNDKHAIRFIPRENGVHSIDVRFNG-SHIPGSPFKIRV-GEPGQVGD-------------------------PGMVSAFGPGLEGGTTGVPSDFIVNTCNAGSGALSVTIDGPSKVKMDCQEC------PEGYKVTYTPMAPGSYLISIKYGGPQHIVGSPFKAKV 2419 HSP 3 Score: 93.9745 bits (232), Expect = 2.158e-18 Identity = 87/315 (27.62%), Postives = 135/315 (42.86%), Query Frame = 2 Query: 965 LELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKN--AAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVI-------LDTKGRKDSVKPKITKQSENKFLIEYT------------------TKEEGLHSVN----VFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV 1816 L+ G + + A F V N +G +D V P G E C I + N + ++ +IP G + I ++F S IP SPFK+ V GDP V+A GPG+E G G + F V T AG G++ I +D + + K T + +LI + G HS++ V V SS G S +SDA + + G G+ + ++ F V AG L V V+GP E+ +K + +Y +Y + G Y++ +K+G+ + SPF+V V Sbjct: 2243 LQEMGLKVNHEASFAVQ-LNGARGVIDAKVHTPSGAVEECYITELDNDK--HAIRFIPRENGVHSIDVRFNGSHIPGSPFKIRVGEPGQVGDPGMVSAFGPGLE--GGTTGVPSDFIVNTCNAGSGALSVTIDGPSKVKMDCQECPEGYKVTYTPMAPGSYLISIKYGGPQHIVGSPFKAKVSGARLSGGHSLHETSSVLVETVTKTSSVAGSFASLPKFSSDASKVVSRGTGLSKAFIGQKNT--FTVDCSKAGTNMLMVGVHGPKTPCEEVYVKHMGNRMYNVTYTVKEKGDYILIVKWGDEMVPGSPFHVTV 2550 HSP 4 Score: 66.2402 bits (160), Expect = 5.777e-10 Identity = 64/228 (28.07%), Postives = 94/228 (41.23%), Query Frame = 2 Query: 944 VRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSE-IPNSPFKVNVKNA-----------------------------------AGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFL-IEYTTKEEGLHSVNVFFAGVQIQSSPFGVMV 1516 V A+GPGLE G T G P+ F V+T NAG G L + + P K C+ + P Y +Y P G Y I IK+ + I SPFK V A + D SKV + G G+ +G++ F V ++AG + +++ G K + K N+ + YT KE+G + + V + + SPF V V Sbjct: 2335 VSAFGPGLE--GGTTGVPSDFIVNTCNAGSGALSVTIDGPSKVKMDCQ--ECPE---GYKVTYTPMAPGSYLISIKYGGPQHIVGSPFKAKVSGARLSGGHSLHETSSVLVETVTKTSSVAGSFASLPKFSSDASKVVSRGTGLSKA--FIGQKNTFTVDCSKAG---TNMLMVGVHGPKTPCEEVYVKHMGNRMYNVTYTVKEKGDYILIVKWGDEMVPGSPFHVTV 2550
BLAST of Filamin vs. Ensembl Cavefish
Match: flnca (filamin-C [Source:NCBI gene;Acc:103033794]) HSP 1 Score: 1358.2 bits (3514), Expect = 0.000e+0 Identity = 871/2293 (37.99%), Postives = 1260/2293 (54.95%), Query Frame = 2 Query: 941 RVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE----SKIKAFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDC--VDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPS-TVKAECF-DVTGQT---IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIET--YFVVDCKLAGSG--DIGISVLDEK--MRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAG--FTPTVIGPHTVTVECKGNPIGNSPYKVIA---TDRVNTKEYPETETPLLIS--ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXX---------XIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGSTQKGP----------SKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 +V+A GPGLE GN P F + T AG G++ +++++P+G+K+ E+ + + C+Y P +EG + I + FA IP SPFKV++ A+ + S A+G G++P G V F VFT AG G + + G + VK + + + +Y G ++V + + G I SPF V V + + ++ A G G++ V A+F V LG ++ GP ++ +C+ K C + Y P PG Y V + + I SPF + P K++AFGPGL TG IV+ PA F ++ G L + ID D GDG+ Y P P ++ + I N+P SPY L + P KV YGPG+ +G+ +++P F V+ AG ++ +C V G I I N++ T++ +YTP PG++TV+V + IP SP+KV V + +A ++ GPG+ + ++T +F + K AG ++ S + ++D ++ DN D ++T+KYT G + +P+SPF + + D K K+ LN +G+ EF + T G + + + SP+G +P KL+ V + P G + V V GNP+ SP+ V A D + Y ++ A ++ID K + P E + ++ N + S ++ P E Y + + K L VT G GL + A A+F +D + A L V I + A++ +N DGT SV Y P+ G Y +++ Y + + P + + P D + V YGPG+ P GV +D + F V+A+ + G ++ I NP + + + DGTY Y+ DG H I++ YD V V KSP+ V V +G DPSR+RAYGPGLE GI +P FTV+ GAG GGLGL+IEG ++A++ C DNKDG+CSV+Y+P PG+YD++I + + IPGSPF V + D+VD SKVKC GPGL +G R P FTVD SKAG A L V + + +P +L + G V Y P G + V Y + VP SPF + + + KV +G G+ + +P FTI+ RDAGE L + + P + + ++ DGT+T Y DV G YT+ + YG +P SP+ + +C + G + + + + I V+ + AG G ++ K + P G + + G + Y + G Y + + F ++IPN + Q ++ + R ++ +P R ++ F G + VR PS + P + +N DGT+TV+Y P+E GLHE+++ Y+G I GSP +F+VD+ SG VTAYGPGL +G + A FT+VTK+A GGLSLAVEGPSKAEI C DNK+GTC VSYLP APGDY+I +KF KHI GSPFTAKI G+ R SQ+ VG+ +DV L+I+ETD+++L A + +P+G E+ C LK L N ++G+SFTPKEVGEH V+V +SG+H+ NSPFKI VG +EIG ASRV+ +G GL + E +F VDTRNAGYGGL LSIEGPSKV+I+C D DGTC VTY PTEPG YIIN+K+A+ ++PGSPF V + G + E I+R + A ++ +G +C+LNL IP + + TA V SP G E++ D+ +S+RF+P E+G HTVSVK +HV GSPFQFTVGPL +GGPHKV G+G++RG+A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGSCGV+Y V EPGDY SIKFN+EH+P SPF++ I + +D+R +++ +LQ++ + +A+F + +G G I A V SPS + I+ +D ++ ++ F+P ENG+H++ V N S IPGSPF V VGE +G+ G+ G TG EF V+T NAG+GAL+VTIDGPSK +++C E GY Y P APG+Y ISIKYGG HI+GSPF I+G S+ ET S L +T M S G S V C+G GL A IG++N F VD AG ++L VGV GP PCE+V +KHLGN + V Y V+EKG ++++V+WG+ VPGSPF + VP Sbjct: 357 KVQARGPGLEPTGNVTQRPTYFDIYTAGAGAGDVSVVIVDPQGKKDTVEVILENKGDSVFRCTYQPVLEGPHTIHVSFAGQPIPKSPFKVHISEAS-NASSCRATGRGLQPKGVRVKEVADFRVFTKGAGTGELKVSVKGPGGAEVPVK--VRDVGDGVYECDYRPTVPGKYTVTITWGGQAIPRSPFEVEVGVQ---AGLQKVRAWGPGLKTG--MVGKSADFVVEAIGTEVGSLGFSIEGPSQAKIECEDKGDGSC--DVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVRAFGPGLQPTGVIVNMPAEFTIDARQAGKGELKIYAQDAEGCIIDIKITDKGDGTFVCVYVPKKPIKHTIIISWGGVNVPNSPYRV---LVGEGCHPDKVKVYGPGVEKTGLKSSEPTYFTVDCGEAGQGDISIGIKCAAGVVGTAEADIDFDIIKNDNDTFTVKYTPPAPGRYTVMVLFAEKEIPSSPYKVKVEPSHDAGKVRAEGPGLNKTGECMDTPTHFTIFTKGAGKAKPEVHFSTGQKGNPVKDFEII--DNHDYSYTVKYTALQQGNMSI-SVTHGGDPVPKSPFNISVAPPLDLSKVKVQGLNEKVEVGKDQEFTVNTQGAGGQGNVGVKMVSPSGRPIPCKLEPDRAKGVTNVKYIPPEEGQYKVDVSYDGNPVPGSPFAVEALMPADPSKVRAYGPGLKGGIVGKPAPFSIDTKGAGAGG--LGLTVEGPCE-AKIECQDNGDGTCSVSYLPTEAGDYNINILYGEKHIPGSPFKAAVKPALDASRVTVSGPGLERAKAGEVATFTVDCSRAGEAELTVEIVSDSGATAEVRIYNNNDGTFSVTYTPQSDGPYTISIRYGGQMVPKCPIRIQVEPAV-------DTSGVKVYGPGVEPKGVLRDVTTHFIVDARAQNKMGGNHIRVRIINPSGSNTDTHITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFRVSVVEGCDPSRVRAYGPGLEGGIVNKPNCFTVETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPFHVLVRDVVDASKVKCSGPGL-GSGVRAHVPQTFTVDCSKAGLASLDVKLYGPG-GATEPVAVL-NNGDGTHTVNYTPSEEGPYTVAVKYADKDVPRSPFKVHSSPAHDASKVRASGPGLDKAG---VPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKASIQDNKDGTYTVSYVPDVTGRYTITIKYGGDQIPFSPYSIQARPTGDASKCLLSGSLGPNIQMCEETVISVDAKAAGTGKVTCKVLTPDGAELDVDVVENLDGTFDIYYTAPEPGKYVITIRFGGQHIPNSP---FHVQATKEPVVPR-------DEKQPQFRPINLLIPFTVQQGALTGEVRM----PSGKTARPLIRDNKDGTVTVKYAPTERGLHEMDIKYDGNHIPGSPLQFFVDAA-ESGMVTAYGPGLCHGTVNKPATFTVVTKNAAEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDGKHIPGSPFTAKITGDDSLRTSQLNVGSAADVSLKITETDLSSLTASIRAPSGAEQPCLLKTLPNRHIGLSFTPKEVGEHEVSVKKSGKHVNNSPFKIMVGPSEIGEASRVRAFGKGLMEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDIKCEDVEDGTCRVTYCPTEPGNYIINIKFAEKHIPGSPFTVKVTG--EGRMKESIMRKRQAPSIASVGTICDLNLKIP--DVQGMTAQVTSPGGKVVNAELVESGDSTYSVRFVPTEMGSHTVSVKYSGQHVPGSPFQFTVGPLGEGGPHKVRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPI---------------ATLSDDARRLTVTSLQEKDLRVYQEASFAVQRNG-ARGVIDAKVHSPSGVVEECYITDVDADKSAIRFIPRENGVHSIDVKFNGSHIPGSPFNVRVGETGHAGDPGLVSAYGPGLQAGCTGVPAEFVVNTCNAGSGALSVTIDGPSKAKMDCVECAEGYKINYTPMAPGNYLISIKYGGPQHIVGSPFKAKITGVRLSGGHSLHETSSVLVET--MTKSSKVAGAYSSASSSSLSSDGSRVVCQGAGLTRAFIGQKNIFTVDCSKAGTNMLMVGVHGPRTPCEDVYVKHLGNRLYNVTYTVKEKGNYVVIVKWGDETVPGSPFHVTVP 2580 HSP 2 Score: 1112.06 bits (2875), Expect = 0.000e+0 Identity = 847/2592 (32.68%), Postives = 1255/2592 (48.42%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKT-NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE-SKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISV--------LDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNTTP-IGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVK----LQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV----------IATDRVNTKEYPETETPLLISADYA-----IDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIY---------PVQRTNEKAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQ-PQKFTVDLEGAGQGG---LGLSIEGP--ADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIV---PVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIR---------TEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYV--DSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCI--DNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQI-------CVGTTSDVPLRISETDIN----NLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSS-SLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQ--DNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPF------------RXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYN---FTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRP---CEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFE 7612 E+ELAEDA WK IQ+NTFTRW N+HLK N + DLQ DL DGLKLI L++ LS +R H RPNFR KLENV++ L FL+ E ++LV+IDS I D LKLILG+IWTLILHYSI+MP+W+ +D ++ +PKQRLLGWI +K+P P+ NF DW DG A+GALVD CAPGLCP+W WDP Q ++NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L AP+ P+ + + +AYGPG+E EGN + PA FTV+T +AG G + + V +P+G +E ++ + +K+ YS SY+P + G +++ + FA +I SPF VNV GDP+KV A GPG+EP GN R T+F+++TA AG G V VI+D +G+KD+V+ + + ++ F Y EG H+++V FAG I SPF V +S S+A ATGRG+QP+GVRV++VA+F+V T+ AG +L V+V GPG + +++ V +YEC Y P PG Y V I +G I SPF V+V K++A+GPGL G+V K A F VE G E G+LGFSI+GPS+AKI+C D GDGS +V YWPT PG+YAVH++CDDE+I SP+MA I P KV A+GPGL +G+ N PA+F ++ + AG +K D G I ++I D DGT+ C Y PK P KHT+I+S+G VN+P SP++V V E + +KVYGPG+E+ K++ TYF VDC AG GDI I + E D ++ +DN T YT+ + F+E EIP SP+KV +E +D K + LN T + F I T G K +PE+ + PVK + + + +T G +++V G+P+ SP+ + + +N K + ++ A + K + P+ KL P V + P EE Y PV + E P V AYG GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP E G Y +N+LY ++HI SPF + P D ++VT GPGL + FTV+ G+ + I + + + NN+DGT+S +Y+P DG + I I Y G V K P + V D S ++ YGPG+E +G+ + F VD + G + + I P ++ D DGT V+Y + G + + + ++E +P SPF V + + D S+V+ YGPGLE G V P+ FTV+ ++ A I+ A+++ + + G V Y+P GN +I + Y +PGSPF V + + KV +G G+ G + VP FT++ AG + L++ + GP + + V N+GDGT T Y G YTV V Y +K+VP SPF V P H +K GP L++ VP V ++ ++AG+G+L+ + + P G SI++ + G TVSYVP G Y + + + + IP F P YSI+ T + SK ++ E +V+ V+ DV ++ N DGT + Y E G + + + + GQ I SPF + +P + +P ++ G L+ V PS + + DNK+GT V Y P G + + IK+ HI GSP + F + + + C GT + P + N L+ V P+ E SC K ++G +S+ P G++ + V G+HIP SPF + ++ S+ LN G + + +T L+ SI PS E C + H G +++ P E G + ++VK + +V SPF + +G PS R+ + V E + S+ PS CE + D + + P E G + +++K +H+ GSPF V G K IM +A+ + + ++ + P ++ + ++ D + V + E G + S+K++ +HVPGSPF + P + Q G F I G +S V PS E S + V ++ E G + V + NN IP SPF R+ V + ++ + F N G + + PS V C + + ++P G ++I +K+ G +HI GSPF V + + + P V G GL+ G EF+V+ AG L V + GP + C E +++NY G +L+ +++G + GSPF+ Sbjct: 5 EKELAEDAPWKKIQQNTFTRWCNEHLKCINKNVTDLQRDLGDGLKLIALLEVLSQKKMYRKHHVRPNFRQMKLENVSVALEFLDR-ERIKLVSIDSKAIVDGNLKLILGMIWTLILHYSISMPMWDDDDDEEKKKL----TPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWETWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPVKPRQLHPKKAKAYGPGIEPEGNMVMKPAVFTVETLDAGLGEVIVYVEDPEGYREEAKVVPNNDKKRTYSVSYVPKVAGPHKVKVLFAGQDIDKSPFSVNVAKTVGDPNKVQARGPGLEPTGNVTQRPTYFDIYTAGAGAGDVSVVIVDPQGKKDTVEVILENKGDSVFRCTYQPVLEGPHTIHVSFAGQPIPKSPFKVHISEA---SNASSCRATGRGLQPKGVRVKEVADFRVFTKGAGTGELKVSVKGPGGAEVPVKVRDVGDGVYECDYRPTVPGKYTVTITWGGQAIPRSPFEVEVGVQAGLQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGSLGFSIEGPSQAKIECEDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVRAFGPGLQPTGVIVNMPAEFTIDARQAGK-GELKIYAQDAEGCIIDIKITDKGDGTFVCVYVPKKPIKHTIIISWGGVNVPNSPYRVLVGEGCHPDKVKVYGPGVEKTGLKSSEPTYFTVDCGEAGQGDISIGIKCAAGVVGTAEADIDFDIIKNDNDTFTV---KYTPPAPGRYTVMVLFAEKEIPSSPYKVKVEPSHDAGKVRAEGPGLNKTGECMDTPTHFTIFTKGAG-KAKPEVHFSTGQKGN-PVKDFEIIDNHDYSYTVKYTALQQGNMSISVTHGGDPVPKSPFNISVAPPLDLSKVKVQGLNEKVEVGKDQEFTVNTQGAGGQGNVGVKMVSPSGRPI-PCKLEPDRAKGVTNV--------KYIPPEEGQYKVDVSYDGNPVPGSPFAVEALMPADPSKVRAYGPGLKGGIVGKPAPFSIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEAGDYNINILYGEKHIPGSPFKAAVKPAL-------DASRVTVSGPGLERAKA--GEVATFTVDC---SRAGEAELTVEIVSDSGATAEVRIYNNNDGTFSVTYTPQSDGPYTISIRYGGQMVPKCPIRIQVEPAVDTSGVKVYGPGVEPKGVLRDVTTHFIVDARAQNKMGGNHIRVRIINPSGSNTDTHITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFRVSVVEGCDPSRVRAYGPGLE--GGIVNKPNCFTVE-TRGAGAGGLGLTIEGASEAKMSCK---DNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPFHVLVRDVVDASKVKCSGPGL----GSGVRAHVPQTFTVDCSKAGLASLDVKLYGPGGATEPVAVLNNGDGTHTVNYTPSEEGPYTVAVKYADKDVPRSPFKVHSSPAHDASK---VRASGPGLDKAGVPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKASIQDNKDGTYTVSYVPDVTGRYTITIKYGGDQIP--------FSP---YSIQARP---TGDASKCLLSGSLGPNIQMCEETVISVDAKAAGTGKVTCKVLTPDGAELDV-DVVENLDGTFDIYYTAPEPGKYVITIRFGGQHIPNSPFHVQATKEPVVPRDE----------KQPQFRPINLLIPFTVQQGALTGEVRMPSGKTARPLIRDNKDGTVTVKYAPTERGLHEMDIKYDGNHIPGSPL--QFFVDAAESGMVTAYGPGLCHGTVNK-PATFTVVTKNAAEGGLSLAVEGPSKAEISC--KDNKDGTCTVSYLPTAPGDYNIIVKFDGKHIPGSPFTAKITGDDSLRTSQ-------LNVGSAADVSLKITETD---LSSLTASIRAPSGAEQPCLLKTLPNRHIG---LSFTPKEVGEHEVSVKKSGKHVNNSPFKIMVG--PSEIGEASRVRAFGKGLMEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDIKCEDV--EDGTCRVTYCPTEPGNYIINIKFAEKHIPGSPFTVKV---TGEGRMKESIMRKRQAPSIASVGTICDLNLKIPDVQGMTAQVTSPGGKVVNAELVESGDSTYSVRFVPTEMGSHTVSVKYSGQHVPGSPFQFTV--GPLGE------------GGPHKVRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAE--ISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPIATLSDDARRLTVTSLQEKDLRVYQEAS------FAVQRNGARGVIDAKVHSPSGVVEECYITDVDADKSAIRFIPRENGVHSIDVKFNG-SHIPGSPFNVRVGETGHAGD--------------------------PGLVSAYGPGLQAGCTGVPAEFVVNTCNAGSGALSVTIDGPSKAKMDCVEC------AEGYKINYTPMAPGNYLISIKYGGPQHIVGSPFK 2443 HSP 3 Score: 124.02 bits (310), Expect = 2.108e-27 Identity = 117/487 (24.02%), Postives = 196/487 (40.25%), Query Frame = 2 Query: 6212 VISPSGSFEMCEIIALSDNQ--FSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVE--RGLANDANQFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPF------RXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEI--GKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 V P G E +++ +D + +S+ ++PK G H V V + + SPF V + G P+KV G G+E + F IYT AGAG +S+ I P E+ ++ D TY+ G + + F + +P SPF + I E +S + LQ +G + A+F + G G + V P E + + + Y + P G + V + IP SPF + + +V G G+ G G+ +F V+ G+L +I+GPS+ ++ C++ G + Y P PGDY + + + I SPF H++ + P K V+ G GL+ + EF +DA AG L + ++ I G+ F Y ++ +H +++ WG +VP SP+ ++V Sbjct: 294 VEDPEGYREEAKVVPNNDKKRTYSVSYVPKVAGPHKVKVLFAGQDIDKSPFSVNVAKTV-GDPNKVQARGPGLEPTGNVTQRPTYFDIYTAGAGAGDVSVVIVDPQGKKDTVEVILENKGDSVFRCTYQPVLEGPHTIHVSFAGQPIPKSPFKVHISEASNASSCRATGR--------------GLQPKGVRVKEVADFRVFTKGAGTGELKVSVKGPGGAEVPVKVRDVGDGVYECDYRPTVPGKYTVTITWGGQAIPRSPFEVEVGVQAGLQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGSLGFSIEGPSQAKIECEDKGDGSCDVRYWPTEPGDYAVHV-ICDDEDIKDSPFMA-----------------------HILPAANDVFPEK---VRAFGPGLQPTGVIVNMPAEFTIDARQAGKGELKIYAQDAEGCIIDIKITDKGDGTFVCVYVPKKPIKHTIIISWGGVNVPNSPYRVLV 738
BLAST of Filamin vs. Ensembl Cavefish
Match: FLNB (filamin B [Source:NCBI gene;Acc:103028460]) HSP 1 Score: 1347.41 bits (3486), Expect = 0.000e+0 Identity = 850/2292 (37.09%), Postives = 1261/2292 (55.02%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES----KIKAFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKG----PSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPS-TVKAEC----FDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGIS----VLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVP--VKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIAT---DRVNTKEYPETETPLLIS--ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQRTNE---------KAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGP-ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXX---------XXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLT-----QTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 ++ +V A GPGLE GN P F + T AG G + ++ +P+G K E + + C+Y P G + + I F IP SP+ V V A P A+G G++P G V + F V T AG G + + KG ++ VK +T+ + + EY +G ++V + + G I SPF V+V + + A++ A G G+ EG V A+F + + LG + GP ++ +C+ + C + Y P PG Y V + + I SPF + P +S ++KA+GPGL +G I++KPA F VE N G L + P E K+ + GD + TY PT ++ V + ++P SP+ + K P KV +GPG+ +G+ ++P F V+ AG +V +C + + I N + T + +Y P G+ T+ V + + IP SPF+V V + +A+ +K GPG+ RA ++ T+F V K AG + + + E ++D ++ DN D ++T+KYTP G + F I +SPF V + + D K ++N L + +GQ EF + T G + + E + SP+G VP V+ Q + + P G +TV + +GNP+ SP+ V A D K + L+ A++ ID K + + T + ++ N + S ++ P E Y V E A+++ P V A G GL +G + +D + P L + + +AK + +DN DGT +V Y+P G Y + + Y + + + P V + P D +KV +GPG+ G+F+++ + FTV+A+ + G +KA + NP + C + + DGTY Y+P +G H +++ YD PV KSP+ V V +G DP+R+ A GPGLEEG+T + KF++ GAG GGLG+++EGP+++++ C DNKDG+C+V+Y P PG YDV+I + +HI GSPF VP+ D+VD SKVK GPG+ +G R P FTVD SKAG APL V V T K V + + G V Y P G + V Y + +VP SPF VL + + KV +G G+ + +P FTI+ +DAGE L + +T + + ++ ++ DGT+ Y D G YT+ + YG +P SP+ V + +C + GP I + +G+ V VNT+ AG G +S V P G V + G + Y K G Y + + F ENIP + + + T Y S + T + D P + V+ PS + P +I+N DGT+ V+Y P+E+GLHE+ + YNG I SP +FYV++ S VTAYGPGL YG + A FTI T+DA GGL LA+EGPSKAEI CIDNK+GTC V+YLP PGDY+I +++ +KHI GSPFTA+I + K+RSQ+ +G+ +D L I+ETD++ L A + +P+GR+E C LKR N +GISF P+EVGEHLV++ ++GRH+ NSP I V ++EIG+A RV+++G GL +G E FVVDTR+AGYGGL+LSIEGPSKV+I+ D DGTC V+Y PTEPGTYI+++++A+ +VPGSPF+V + G + E I R Q AA V+ +G+VC+LNL IP + + +A V SPSGS E EI+ + ++ + +RF+P E+GVHTV+VK +HV GSPFQFTVGPL +GG +KV G G+ER +F+I+TREAGAG LSIA+EGPS+AEI F+D KDGSCGV+Y NEPGDY S+KFN+EH+P SP+++ PV + +D+R +++ +LQ+ G + +F + +G G+I A V SPS + +S+++ ++Y++ F+P ENGIH + V N + IPGSPF V G VT G G+ G TG +F ++T+ AG G+L VTI+GPSKV++ CQE G+ Y P APG+Y ISIKYGG NHI GSPF + G + + E+ +LT + S S+ + S V G GL A +G+R F VD AG ++L VGV GP PCEE+ +KH+G+ ++ V+Y ++E+G +LL V+WG +PGSPF + VP Sbjct: 352 DASKVTAKGPGLEPLGNIANKPTYFDIYTAGAGVGEVTAVIKDPQGNKNTVEALMEDKGDSVFRCTYRPVQAGPHSVNITFGGIAIPKSPYTVTV-GPASSPGACRATGRGLQPRGVRVRQVADFRVDTRSAGSGELKVTVKGPKGLEEPVK--LTEAMDGTYAYEYYPNTQGKYTVTITWGGQHIPKSPFEVVVGPE---AGAQKIRAWGPGL--EGGIVGRSADFVAESIGSDVGVLGFAIEGPSQARIECEDQNDGSC--DVKYWPTEPGEYAVHVMCDDEDIEDSPFMAYIVPDDKSSDPSQVKAYGPGLEKSGCIINKPAEFTVEAKNAGKGPLKIIAQNADGEPIEVKMR--NKGDNVYSCTYTPTSALKHTVAVTWGGVSVPNSPFRVNVG---KGSHPHKVKVFGPGVERTGLKAHEPTHFTVDCTEAGEGDVSVGIKCDANIISDKEEDVDFDIIPNANDTITVKYIPPGAGRLTIKVLFTDQEIPVSPFRVKVEPSHDASKVKADGPGLARAGVESGKPTHFTVHTKGAGKAPLDVQFSGPIKGEPVQDFEII--DNYDYSYTVKYTPVQQGEMVI-NVTFGGDPISKSPFAVGVAAPLDLSKIQVNGLESRVEVGQDQEFAVSTKGAGGQGKLEARITSPSGKSVPCAVEPQPGKGASLVKYIPKEEGVYTVEILYEGNPVPGSPFPVDAMLPPDPSKVKAFGPGLKGGLVGNPAEFTIDTKGAGTGGLGLTVEGPT---EAKIECSDNGDGTCSVSYLPTEPGEYLVNILFEDVHVPGSPFHADIQYPFDPTKVVASGSGLKRGKVGEISVVNVDCAKAGPGQLTLEAMSDAGSKAKTEVLDNKDGTYTVTYVPLTAGMYTLLLKYGGQAVPNFPAKVVVDPAV-------DTSKVKVFGPGVAGEGLFREATTDFTVDARALTKVGGKHIKAQVKNPSGAATDCVIADQGDGTYKVEYTPFENGVHAVEVLYDDTPVPKSPFQVGVGEGCDPARVVAKGPGLEEGLTDKANKFSIITRGAGIGGLGITVEGPSESKMSCKDNKDGSCNVEYTPYAPGLYDVNITYGGQHIQGSPFKVPVKDVVDASKVKLSGPGV-GSGVRAKIPQSFTVDCSKAGVAPLAVAV--TGPKGVAEPVDVIDNGDGTHTVAYTPSVEGPYSVVVKYADEEVPRSPFKLRVLPTHDASKVRASGPGLTTG----LPASLPVEFTIDAKDAGEGQLSVQITDQDGKLKTANISDNQDGTYKVSYVPDKVGRYTIVIKYGGDEIPTSPYRVRATTSGDASKCTVTGPGIGPTIGIGEEVGFVVNTKGAGKGKVSCVVVTPDGTEVEADVVENEDGTFDIFYTAPKPGTYVIYVRFGGENIP-----------KSPFKVMVTDGAYIPVNS--MNGTGFRPFDMVIPFAFRKGEITGEVHMPSGKTTQPEIIDNKDGTVMVKYAPTEAGLHEMHIKYNGSHIPESPLQFYVNNA-NSPNVTAYGPGLVYGVANKPATFTIYTEDAAEGGLDLAIEGPSKAEITCIDNKDGTCTVTYLPTLPGDYNILVRYNEKHIAGSPFTARITEDNKRRSQVKLGSAADFALDITETDLSLLTASIKAPSGRDEPCLLKRQPNNRIGISFIPREVGEHLVSIKKNGRHVANSPITIMVVQSEIGDAGRVQVFGQGLVEGRTFEMSDFVVDTRDAGYGGLALSIEGPSKVDIQTEDMDDGTCGVSYCPTEPGTYIVSIRFAEDHVPGSPFSVKVTG--EGRIRESISRRQKAASVASVGSVCDLNLKIPEIDALDMSAQVTSPSGSVEPAEIVEVGNHTYCVRFVPHEMGVHTVNVKYRGQHVPGSPFQFTVGPLGEGGANKVKAGGPGLERAEIGVPAEFSIWTREAGAGGLSIAVEGPSRAEISFEDRKDGSCGVSYVANEPGDYEVSVKFNEEHIPESPYLV------------PVMAPS---DDARRLTVTSLQESGLKVNQPTSFAVRLNG-AQGAIDAKVHSPSGALEECVVSELEQDKYAIRFIPRENGIHTIDVKFNGTHIPGSPFEVRVGEPGQGGDAGLVTAYGSGLERGTTGNQADFIINTTKAGPGSLAVTIEGPSKVKMECQECSEGFKVQYTPMAPGNYLISIKYGGPNHINGSPFRAKVMGPRLVNVTNASESSTLTVDPVIRPSSANSYSSLRAASDASKVSSRGSGLSKAYVGQRASFSVDCSKAGKNMLLVGVHGPQTPCEEIMVKHMGSLQYNVSYVLKERGSYLLAVKWGEDHIPGSPFHVTVP 2576 HSP 2 Score: 1089.33 bits (2816), Expect = 0.000e+0 Identity = 845/2580 (32.75%), Postives = 1245/2580 (48.26%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNK-ELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKES-KIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGS-PSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGI------SVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINN---LNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVK----LQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYP----ETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS----NFEPNEEIIYPVQRTNEK----------AELRKPN---VTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTI-YPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQP-QKFTVD---LEGAGQGGLGLSIEGPADAQIQCF--DNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPF---IVPVHSEAKPEQCYIEGPILNE-VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVD--STIPSGQVTAYGPGLSYGRP-DMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQ--CIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFT----------------AKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIEC--HDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEM-CEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVG--PLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSK----AEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXI---HHGHTG-RINE--FFVDTSNAGNGALTVTIDGPSKVQLNC---QENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWG--NHDVPGSPFEIVV 7621 E++LAEDA WK IQ+NTFTRW N+HLK N I DLQ DL+DGL+LI L++ LS +R H+RP FR KLENV++ L FL+ E +RLV+IDS I D LKLILG++WTLILHYSI+MP+WEGE +D + K +PKQRLLGWI K+P P+ NF+ DW DG A+GALVD+CAPGLCP+W WD ++ ++NA EA+ A++ L + +I P E+I+P VDE+++MTYLSQFP A+L APL PK N + RAYGPG+E GN + PA FTVDTF+AG+G + + + +P+G++E E+ PN+ + +S +YIP + G +++ + FA +IP SPF+VNV A GD SKVTA GPG+EP+GN + T+F+++TA AG G V VI D +G K++V+ + + ++ F Y + G HSVN+ F G+ I SP+ V V +S + ATGRG+QP GVRVR VA+F+V T AG +L V V GP E ++ + Y Y P G Y V I +G I SPF V V P + KI+A+GPGL GGIV + A F E+ G + G LGF+I+GPS+A+I+C D DGS +V YWPT PGEYAVH++CDDE+I SP+MA I D K DP +V AYGPGL SG NKPA+F V KNAG P + A+ D G+ I V++R+ D YSC YTP KHTV V++G V++P SPF+VNV + + +KV+GPG+ER K + T+F VDC AG GD+ + +++ +K DV N + T TI++ F++ EIP SPF+V +E +D K K + G+ F + T G K ++ P PV+ + + + +TP G + V G+PI SP+ V ++ + E+ + ++A+ K A++T +V P + + P EE +Y V+ E + P+ V A+G GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP EPG Y+VN+L+ D H+ SPF+ I YP D KV A G GL + + +V G G + + ++ V +N DGTY+ +Y P G + + + Y G V P V V D S+++ +GPG+ EG+ ++ FTVD L G + ++ P+ A C D DGT V+Y P + G + V + +++ +P SPF V + + D ++V GPGLE + ++F++ AG L + V + + + G +V Y P G ++ + Y + GSPF V + + KV ++G GV G + K+P FT++ AG + L + VTGP + +DV ++GDGT T Y V G Y+V V Y ++ VP SPF ++P H +K GP L +P V ++ ++AG+G LS + G + +I + + G VSYVP K+G Y + + + + IP R A S + + T P I V G V VV P + ++ N DGT + Y + G + + V + G+ I SPFK V + IP + G RP DM F G ++ V PS Q IDNK+GT V Y P G + + IK+ HI SP ++G K + + T + L+ + P+ E +C + +G +++ P G++ + V + +HI SPF + E+ S+VKL F +D L+ SI+ PS + C + +++ P E G +++++K +V SP + + S R Q + G E++ + +S G ++ + + D + + P E G + VS++ HV GSPF V I + S G D N + E A +S + PS AEI N + V + +E G + ++K+ +HVPGSPF + P + + + IG A F I G +S V PS E S + V +V E G + V V N IP SP+ V V + + +G ++N+ F N GA+ + PS C + + Y ++P G +TI +K+ G HI GSPF V + G Q D+ V G GL+ G + +FI++ AG L V + GP + C+E + F+V Y G +L+ +++G NH + GSPF V Sbjct: 5 EKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIADLQLDLSDGLRLIALLEILSQKKMYRKFHQRPTFRQMKLENVSVALEFLDR-ENIRLVSIDSKAIVDGNLKLILGMVWTLILHYSISMPVWEGE----EDDEAKKATPKQRLLGWIQHKVPDLPITNFSQDWKDGKALGALVDSCAPGLCPDWETWDTEKPVENATEAMQLADDWLGIPQVIAPEEIIDPSVDEQSVMTYLSQFPKAKLKPGAPLKPKLNPKKARAYGPGIEPVGNRVMRPAVFTVDTFSAGQGQVTVYIEDPEGRRE--EVKAVPNEGKKTFSVAYIPQVMGPHKVTVLFAGQQIPKSPFEVNVDKAQGDASKVTAKGPGLEPLGNIANKPTYFDIYTAGAGVGEVTAVIKDPQGNKNTVEALMEDKGDSVFRCTYRPVQAGPHSVNITFGGIAIPKSPYTVTVGPASSPGACR---ATGRGLQPRGVRVRQVADFRVDTRSAGSGELKVTVKGPKGLEEPVKLTEAMDGTYAYEYYPNTQGKYTVTITWGGQHIPKSPFEVVVGPEAGAQKIRAWGPGLEGGIVGRSADFVAESIGSDVGVLGFAIEGPSQARIECEDQNDGSCDVKYWPTEPGEYAVHVMCDDEDIEDSPFMAYIVPDDKSSDPSQVKAYGPGLEKSGCIINKPAEFTVEAKNAGKGPLKIIAQNAD--GEPIEVKMRNKGDNVYSCTYTPTSALKHTVAVTWGGVSVPNSPFRVNVGKGSHPHKVKVFGPGVERTGLKAHEPTHFTVDCTEAGEGDVSVGIKCDANIISDKEEDVDFDIIPNANDTI-TVKYIPPGAGRLTIKVLFTDQEIPVSPFRVKVEPSHDASKVKADGPGLARAGVESGKPTHFTVHTKGAG-KAPLDVQFSGPIKGE-PVQDFEIIDNYDYSYTVKYTPVQQGEMVINVTFGGDPISKSPFAVGVAAPLDLSKIQVNGLESRVEVGQDQEFAVSTKGAGGQG--KLEARITSPSGKSVPCAVEPQPGKGASLVKYIPKEEGVYTVEILYEGNPVPGSPFPVDAMLPPDPSKVKAFGPGLKGGLVGNPAEFTIDTKGAGTGGLGLTVEGPTEAKIECSDNGDGTCSVSYLPTEPGEYLVNILFEDVHVPGSPFHADIQYP--------FDPTKVVASGSGLK-----RGKVGEISVVNVDCAKAGPGQLTLEAMSDAGSKAKTEVLDNKDGTYTVTYVPLTAGMYTLLLKYGGQAVPNFPAKVVVDPAVDTSKVKVFGPGVAGEGLFREATTDFTVDARALTKVGGKHIKAQVKNPSGAATDCVIADQGDGTYKVEYTPFENGVHAVEVLYDDTPVPKSPFQVGVGEGCDPARVVAKGPGLEEGLTD--KANKFSIITRGAGIGGLGITVEGPSESKMS----CKDNKDGSCNVEYTPYAPGLYDVNITYGGQHIQGSPFKVPVKDVVDASKVKLSGPGV----GSGVRAKIPQSFTVDCSKAGVAPLAVAVTGPKGVAEPVDVIDNGDGTHTVAYTPSVEGPYSVVVKYADEEVPRSPFKLRVLPTHDASK---VRASGPGLTTGLPASLPVEFTIDAKDAGEGQLSVQITDQDGKLKTANISDNQDGTYKVSYVPDKVGRYTIVIKYGGDEIPTSPYRVRA-----TTSGDASKCTVTGPGIGPTIGIGEEVGFVVNTKGAGKGKVSCVVVTPDGTEVEADVVENEDGTFDIFYTAPKPGTYVIYVRFGGENIPKSPFKVMVTDGAYIPVNSMNGTG-----FRPFDMVIPFAFRK-----GEITGEVHMPSGKTTQPEIIDNKDGTVMVKYAPTEAGLHEMHIKYNGSHIPESPLQFYVNNANSPNVTAYGPGLVYGVANKPATFTIYT--------EDAAEGGLDLAIEGPSKAEITCIDNK--DGTCTVTYLPTLPGDYNILVRYNEKHIAGSPFTARITEDN-KRRSQVKL----------GSAADFALDITETDLSLLTASIKAPSGRDEPCLLKRQPNNRIGISFIPREVGEHLVSIKKNGRHVANSPITIMV----VQSEIGDAGRVQVFGQGLVEGRTFEMSDFVVDTRDAGYGGLALSIEGPSKVDIQTEDMDDGTCGVSYCPTEPGTYIVSIRFAEDHVPGSPFSVKVTGEGRIRESISRRQKAASVASVGSVCDLN---LKIPEIDALDMSAQVTSPSGSVEPAEIVEVGNH--TYCVRFVPHEMGVHTVNVKYRGQHVPGSPFQFTV--GPLGE------------GGANKVKAGGPGLERAEIGVPAEFSIWTREAGAGGLSIAVEGPSRAE--ISFEDRKDGSCGVSYVANEPGDYEVSVKFNEEHIPESPYLVPVMAPSDDARRLTVTSLQESGLKVNQPTSFAVRLNGAQGAIDAKVHSPSGALEECVVSELEQDKYAIRFIPRENGIHTIDVKFNG-THIPGSPFEVRV-GEPGQGGDAGL-------------------------VTAYGSGLERGTTGNQADFIINTTKAGPGSLAVTIEGPSKVKMECQEC------SEGFKVQYTPMAPGNYLISIKYGGPNH-INGSPFRAKV 2446
BLAST of Filamin vs. Ensembl Cavefish
Match: flnca (filamin-C [Source:NCBI gene;Acc:103033794]) HSP 1 Score: 1063.91 bits (2750), Expect = 0.000e+0 Identity = 758/2165 (35.01%), Postives = 1105/2165 (51.04%), Query Frame = 2 Query: 176 ERELAEDAQWKVIQKNTFTRWANQHLKPSNLIIDDLQYDLADGLKLINLVQELSGSN-FRHTHKRPNFRTQKLENVTMVLRFLEESEGLRLVNIDSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKT-NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE-SKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLI-SGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISV--------LDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKIN--NLNNT-TPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVK----LQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKV----------IATDRVNTKEYPETETPLLISADYA-----IDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIY---------PVQRTNEKAELRKP----NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGITKQ-PQKFTVDLEGAGQGG---LGLSIEGP--ADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIV---PVHSEAKPEQCYIEGPILNE--VPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRT-----------------EYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYV--DSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCI--DNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQI-------CVGTTSDVPLRISETDIN----NLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-----DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSS-SLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTV 6370 E+ELAEDA WK IQ+NTFTRW N+HLK N + DLQ DL DGLKLI L++ LS +R H RPNFR KLENV++ L FL+ E ++LV+IDS I D LKLILG+IWTLILHYSI+MP+W+ +D ++ +PKQRLLGWI +K+P P+ NF DW DG A+GALVD CAPGLCP+W WDP Q ++NA+EA+ A++ L V +I P E+++P VDE ++MTYLSQFP A+L AP+ P+ + + +AYGPG+E EGN + PA FTV+T +AG G + + V +P+G +E ++ + +K+ YS SY+P + G +++ + FA +I SPF VNV GDP+KV A GPG+EP GN R T+F+++TA AG G V VI+D +G+KD+V+ + + ++ F Y EG H+++V FAG I SPF V +S S+A ATGRG+QP+GVRV++VA+F+V T+ AG +L V+V GPG + +++ V +YEC Y P PG Y V I +G I SPF V+V K++A+GPGL G+V K A F VE G E G+LGFSI+GPS+AKI+C D GDGS +V YWPT PG+YAVH++CDDE+I SP+MA I P KV A+GPGL +G+ N PA+F ++ + AG +K D G I ++I D DGT+ C Y PK P KHT+I+S+G VN+P SP++V V E + +KVYGPG+E+ K++ TYF VDC AG GDI I + E D ++ +DN T YT+ + F+E EIP SP+KV +E +D K + LN T + F I T G K +PE+ + PVK + + + +T G +++V G+P+ SP+ + + +N K + ++ A + K + P+ KL P V + P EE Y PV + E P V AYG GL G+ PA F ID+ LG+T+EGP EAKI+ DNGDGTCSV+YLP E G Y +N+LY ++HI SPF + P D ++VT GPGL + FTV+ G+ + I + + + NN+DGT+S +Y+P DG + I I Y G V K P + V D S ++ YGPG+E +G+ + F VD + G + + I P ++ D DGT V+Y + G + + + ++E +P SPF V + + D S+V+ YGPGLE G V P+ FTV+ ++ A I+ A+++ + + G V Y+P GN +I + Y +PGSPF V + + KV +G G+ G + VP FT++ AG + L++ + GP + + V N+GDGT T Y G YTV V Y +K+VP SPF V P H +K GP L++ VP V ++ ++AG+G+L+ + + P G SI++ + G TVSYVP G Y + + + + IP F P YSI+ T + SK ++ E +V+ V+ DV ++ N DGT + Y E G + + + + GQ I SPF + +P + +P ++ G L+ V PS + + DNK+GT V Y P G + + IK+ HI GSP + F + + + C GT + P + N L+ V P+ E SC K ++G +S+ P G++ + V G+HIP SPF + ++ S+ LN G + + +T L+ SI PS E C + H G +++ P E G + ++VK + +V SPF + +G PS R+ + V E + S+ PS CE + D + + P E G + +++K +H+ GSPF V Sbjct: 33 EKELAEDAPWKKIQQNTFTRWCNEHLKCINKNVTDLQRDLGDGLKLIALLEVLSQKKMYRKHHVRPNFRQMKLENVSVALEFLDR-ERIKLVSIDSKAIVDGNLKLILGMIWTLILHYSISMPMWDDDDDEEKKKL----TPKQRLLGWIQNKVPQLPINNFNRDWRDGKALGALVDNCAPGLCPDWETWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPDVDEHSVMTYLSQFPKAKLKPGAPVKPRQLHPKKAKAYGPGIEPEGNMVMKPAVFTVETLDAGLGEVIVYVEDPEGYREEAKVVPNNDKKRTYSVSYVPKVAGPHKVKVLFAGQDIDKSPFSVNVAKTVGDPNKVQARGPGLEPTGNVTQRPTYFDIYTAGAGAGDVSVVIVDPQGKKDTVEVILENKGDSVFRCTYQPVLEGPHTIHVSFAGQPIPKSPFKVHISEA---SNASSCRATGRGLQPKGVRVKEVADFRVFTKGAGTGELKVSVKGPGGAEVPVKVRDVGDGVYECDYRPTVPGKYTVTITWGGQAIPRSPFEVEVGVQAGLQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGSLGFSIEGPSQAKIECEDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVRAFGPGLQPTGVIVNMPAEFTIDARQAGK-GELKIYAQDAEGCIIDIKITDKGDGTFVCVYVPKKPIKHTIIISWGGVNVPNSPYRVLVGEGCHPDKVKVYGPGVEKTGLKSSEPTYFTVDCGEAGQGDISIGIKCAAGVVGTAEADIDFDIIKNDNDTFTV---KYTPPAPGRYTVMVLFAEKEIPSSPYKVKVEPSHDAGKVRAEGPGLNKTGVQVDTPTHFTIFTKGAG-KAKPEVHFSTGQKGN-PVKDFEIIDNHDYSYTVKYTALQQGNMSISVTHGGDPVPKSPFNISVAPPLDLSKVKVQGLNEKVEVGKDQEFTVNTQGAGGQGNVGVKMVSPSGRPI-PCKLEPDRAKGVTNV--------KYIPPEEGQYKVDVSYDGNPVPGSPFAVEALMPADPSKVRAYGPGLKGGIVGKPAPFSIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEAGDYNINILYGEKHIPGSPFKAAVKPAL-------DASRVTVSGPGLERAKA--GEVATFTVDC---SRAGEAELTVEIVSDSGATAEVRIYNNNDGTFSVTYTPQSDGPYTISIRYGGQMVPKCPIRIQVEPAVDTSGVKVYGPGVEPKGVLRDVTTHFIVDARAQNKMGGNHIRVRIINPSGSNTDTHITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFRVSVVEGCDPSRVRAYGPGLE--GGIVNKPNCFTVE-TRGAGAGGLGLTIEGASEAKMSCK---DNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPFHVLVRDVVDASKVKCSGPGL----GSGVRAHVPQTFTVDCSKAGLASLDVKLYGPGGATEPVAVLNNGDGTHTVNYTPSEEGPYTVAVKYADKDVPRSPFKVHSSPAHDASK---VRASGPGLDKAGVPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKASIQDNKDGTYTVSYVPDVTGRYTITIKYGGDQIP--------FSP---YSIQARP---TGDASKCLLSVSIGGRGVGSLGPNIQMCEETVISVDAKAAGTGKVTCKVLTPDGAELDV-DVVENLDGTFDIYYTAPEPGKYVITIRFGGQHIPNSPFHVQATKEPVVPRDE----------KQPQFRPINLLIPFTVQQGALTGEVRMPSGKTARPLIRDNKDGTVTVKYAPTERGLHEMDIKYDGNHIPGSPL--QFFVDAAESGMVTAYGPGLCHGTVNK-PATFTVVTKNAAEGGLSLAVEGPSKAEISC--KDNKDGTCTVSYLPTAPGDYNIIVKFDGKHIPGSPFTAKITGDDSLRTSQ-------LNVGSAADVSLKITETD---LSSLTASIRAPSGAEQPCLLKTLPNRHIG---LSFTPKEVGEHEVSVKKSGKHVNNSPFKIMVG--PSEIGEASRVRAFGKGLMEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDIKCEDV--EDGTCRVTYCPTEPGNYIINIKFAEKHIPGSPFTVKV 2102 HSP 2 Score: 985.712 bits (2547), Expect = 0.000e+0 Identity = 741/2302 (32.19%), Postives = 1116/2302 (48.48%), Query Frame = 2 Query: 941 RVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE----SKIKAFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDC--VDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPS-TVKAECF-DVTGQT---IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIET--YFVVDCKLAGSG--DIGISVLDEK--MRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAG--FTPTVIGPHTVTVECKGNPIGNSPYKVIA---TDRVNTKEYPETETPLLIS--ADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIYPVQ-------------RTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTI--EGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIE--------GPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPG------YNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPF------------RXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYN---FTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRP---CEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGN-HDVPGSPFE 7612 +V+A GPGLE GN P F + T AG G++ +++++P+G+K+ E+ + + C+Y P +EG + I + FA IP SPFKV++ A+ + S A+G G++P G V F VFT AG G + + G + VK + + + +Y G ++V + + G I SPF V V + + ++ A G G++ V A+F V LG ++ GP ++ +C+ K C + Y P PG Y V + + I SPF + P K++AFGPGL TG IV+ PA F ++ G L + ID D GDG+ Y P P ++ + I N+P SPY L + P KV YGPG+ +G+ +++P F V+ AG ++ +C V G I I N++ T++ +YTP PG++TV+V + IP SP+KV V + +A ++ GPG+ + ++T +F + K AG ++ S + ++D ++ DN D ++T+KYT G + +P+SPF + + D K K+ LN +G+ EF + T G + + + SP+G +P KL+ V + P G + V V GNP+ SP+ V A D + Y ++ A ++ID K + P E + ++ N + S ++ P E Y + + K L VT G GL + A A+F +D + A L V I + A++ +N DGT SV Y P+ G Y +++ Y + + P + + P D + V YGPG+ P GV +D + F V+A+ + G ++ I NP + + + DGTY Y+ DG H I++ YD V V KSP+ V V +G DPSR+RAYGPGLE GI +P FTV+ GAG GGLGL+IEG ++A++ C DNKDG+CSV+Y+P PG+YD++I + + IPGSPF V + D+VD SKVKC GPGL +G R P FTVD SKAG A L V + + +P +L + G V Y P G + V Y + VP SPF + + + KV +G G+ + +P FTI+ RDAGE L + + P + + ++ DGT+T Y DV G YT+ + YG +P SP+ + +C + G + + + + I V+ + AG G ++ K + P G + + G + Y + G Y + + F ++IPN + Q ++ + R ++ +P R ++ F G + VR PS + P + +N DGT+TV+Y P+E GLHE+++ Y+G I GSP +F+VD+ SG VTAYGPGL +G + A FT+VTK+A GGLSLAVEGPSKAEI C DNK+GTC VSYLP APGDY+I +KF KHI GSPFTAKI G+ R SQ+ VG+ +DV L+I+ETD+++L A + +P+G E+ C LK L N ++G+SFTPKEVGEH V+V +SG+H+ NSPFKI VG +EIG ASRV+ +G GL + E +F VDTRNAGYGGL LSIEGPSKV+I+C D DGTC VTY PTEPG YIIN+K+A+ ++PGSPF V + G + E I+R + A ++ +G +C+LNL IPG Q T + S ++ E +S R + VH V+ + PF+ G ++ G + GS + D T G ++ + ++ D + V + E G + S+K++ +HVPGSPF + P + Q G F I G +S V PS E S + V ++ E G + V + NN IP SPF R+ V + ++ + F N G + + PS V C + + ++P G ++I +K+ G +HI GSPF V + + + P V G GL+ G EF+V+ AG L V + GP + C E +++NY G +L+ +++G + GSPF+ Sbjct: 385 KVQARGPGLEPTGNVTQRPTYFDIYTAGAGAGDVSVVIVDPQGKKDTVEVILENKGDSVFRCTYQPVLEGPHTIHVSFAGQPIPKSPFKVHISEAS-NASSCRATGRGLQPKGVRVKEVADFRVFTKGAGTGELKVSVKGPGGAEVPVK--VRDVGDGVYECDYRPTVPGKYTVTITWGGQAIPRSPFEVEVGVQ---AGLQKVRAWGPGLKTG--MVGKSADFVVEAIGTEVGSLGFSIEGPSQAKIECEDKGDGSC--DVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVRAFGPGLQPTGVIVNMPAEFTIDARQAGKGELKIYAQDAEGCIIDIKITDKGDGTFVCVYVPKKPIKHTIIISWGGVNVPNSPYRV---LVGEGCHPDKVKVYGPGVEKTGLKSSEPTYFTVDCGEAGQGDISIGIKCAAGVVGTAEADIDFDIIKNDNDTFTVKYTPPAPGRYTVMVLFAEKEIPSSPYKVKVEPSHDAGKVRAEGPGLNKTGVQVDTPTHFTIFTKGAGKAKPEVHFSTGQKGNPVKDFEII--DNHDYSYTVKYTALQQGNMSI-SVTHGGDPVPKSPFNISVAPPLDLSKVKVQGLNEKVEVGKDQEFTVNTQGAGGQGNVGVKMVSPSGRPIPCKLEPDRAKGVTNVKYIPPEEGQYKVDVSYDGNPVPGSPFAVEALMPADPSKVRAYGPGLKGGIVGKPAPFSIDTKGAGAGG--LGLTVEGPCE-AKIECQDNGDGTCSVSYLPTEAGDYNINILYGEKHIPGSPFKAAVKPALDASRVTVSGPGLERAKAGEVATFTVDCSRAGEAELTVEIVSDSGATAEVRIYNNNDGTFSVTYTPQSDGPYTISIRYGGQMVPKCPIRIQVEPAV-------DTSGVKVYGPGVEPKGVLRDVTTHFIVDARAQNKMGGNHIRVRIINPSGSNTDTHITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFRVSVVEGCDPSRVRAYGPGLEGGIVNKPNCFTVETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPFHVLVRDVVDASKVKCSGPGL-GSGVRAHVPQTFTVDCSKAGLASLDVKLYGPG-GATEPVAVL-NNGDGTHTVNYTPSEEGPYTVAVKYADKDVPRSPFKVHSSPAHDASKVRASGPGLDKAG---VPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKASIQDNKDGTYTVSYVPDVTGRYTITIKYGGDQIPFSPYSIQARPTGDASKCLLSVSIGGRGVGSLGPNIQMCEETVISVDAKAAGTGKVTCKVLTPDGAELDVDVVENLDGTFDIYYTAPEPGKYVITIRFGGQHIPNSP---FHVQATKEPVVPR-------DEKQPQFRPINLLIPFTVQQGALTGEVRM----PSGKTARPLIRDNKDGTVTVKYAPTERGLHEMDIKYDGNHIPGSPLQFFVDAA-ESGMVTAYGPGLCHGTVNKPATFTVVTKNAAEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDGKHIPGSPFTAKITGDDSLRTSQLNVGSAADVSLKITETDLSSLTASIRAPSGAEQPCLLKTLPNRHIGLSFTPKEVGEHEVSVKKSGKHVNNSPFKIMVGPSEIGEASRVRAFGKGLMEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDIKCEDVEDGTCRVTYCPTEPGNYIINIKFAEKHIPGSPFTVKVTG--EGRMKESIMRKRQAPSIASVGTICDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKT----RGGETKREVH---VEESTKVGGRDPFRDIFGSIL--GRESLGCFGSLTSK---EDVQGMTAQVTSPGGKVVN----------AELVESGDSTYSVRFVPTEMGSHTVSVKYSGQHVPGSPFQFTV--GPLGE------------GGPHKVRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAE--ISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPIATLSDDARRLTVTSLQEKDLRVYQEAS------FAVQRNGARGVIDAKVHSPSGVVEECYITDVDADKSAIRFIPRENGVHSIDVKFNG-SHIPGSPFNVRVGETGHAGD--------------------------PGLVSAYGPGLQAGCTGVPAEFVVNTCNAGSGALSVTIDGPSKAKMDCVEC------AEGYKINYTPMAPGNYLISIKYGGPQHIVGSPFK 2560 HSP 3 Score: 591.267 bits (1523), Expect = 2.788e-171 Identity = 573/2002 (28.62%), Postives = 887/2002 (44.31%), Query Frame = 2 Query: 941 RVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEI---FDS-PNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKP-KITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGF-ADLGVNVYGPGRSLEKCQIK-KVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVD-VAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGF-SIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKT--NIETYFVVDCKL---AGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVA-GFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLL-------ISADYAIDNKAYNKPSIPVQ----SAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQ-RTNEKAELRKP------------NVTAYGEGLVK-GV-ANTPASFIIDSTEEPPAPLGVTI---EG-PMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVA----KVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLE---GAGQGGLGLSIEGPA--DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTP-GLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVP-------------GNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIE--GPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIP----------NGSIRQYAFQPQEQYSIE-------------------------------RTTHHYTTEQSKPIIRT------------EYSVVDFKFPVGPVFDYV--RAVVNC---PSNRKDV----------------PRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSG--QVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDI---------NNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGEN-EIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYAD-SNVPGSPFAVNIGGY----------PSSSLTERILRHQDAAEVSQIGN-----------VC-----------ELNLIIPGYNQRNTTASVISPSGSFEMCE---IIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTV 6370 +V+ YGPG+E G P FTVD AG+G++ I + G E FD N ++ Y P G Y +++ FA EIP+SP+KV V+ + D KV A GPG+ G +V T F +FT AG + V T + + VK +I + + ++YT ++G S++V G + SPF + V+ S K +G+ E V V EF V+T+ AG ++GV + P C+++ + + YIP G Y VD+ Y NP+ SPF V+ + P SK++A+GPGL GGIV KPA F ++T G +++GP EAKI+C DNGDG+ +V+Y PT G+Y ++IL +++IP SP+ A ++ D +VT GPGL + A F V+ AG + + E +G T V+I +NNDGT+S YTP+ G +T+ + YG +P+ P ++ V A + + +KVYGPG+E ++ T+F+VD + G I + +++ + D GDGT+ ++YT G ++F+ E +P+SPF+V + D ++ G +N+ T + + S + ++ +G + + P + G + + + G PI SP+ V+ D V+ + + P L + + +D S+ V+ PV N + N+ P+EE Y V + +K R P V A G GL K GV A+ P F ID+ + L V I EG P +A I DN DGT +V+Y+P G Y + + Y + I SP+++ P +S + V+ V + GP + + TV + G G V + P V N DGT+ Y+ G++ I I + G + SP+ V + +P R KQPQ ++L QG L + P+ A+ DNKDGT +V+Y P + G +++ IK++ HIPGSP + D + V YGPGL V P+ FTV A E L + A + A+I K G V+Y+P G+ I V ++ +PGSPF + TG+ SL T +D+ L +T + S+ + C K +P G + V V K+V SPF + V E + G L E + V+T+NAG G L GP + C E+ G V+Y P + G Y + + F +++IP G +++ + ++ SI R++H YT + I +T E + V + P +F + R + C ++++DV L+ +GD T +V++ P+E G H + V Y+GQ + GSPF+F V G +V A G GL G + F+I T++AGAGGLS+AVEGPSKAEI D K+G+C VSY+ PGDY + IKF ++HI SPF I ++ V + + LR+ + ++A V SP+G E C + + I F P+E G H ++V +G HIP SPF + VGE G+ V YG GL G +FVV+T NAG G LS++I+GPSK +++C + +G + Y P PG Y+I++KY ++ GSPF I G SS L E + + A + VC + N+ ++ T ++ G CE + L + +++ + KE G + V VK + V GSPF TV Sbjct: 774 KVKVYGPGVEKTGLKSSEPTYFTVDCGEAGQGDISIGIKCAAGVVGTAEADIDFDIIKNDNDTFTVKYTPPAPGRYTVMVLFAEKEIPSSPYKVKVE-PSHDAGKVRAEGPGLNKTGVQVDTPTHFTIFTKGAGKAKPE-VHFSTGQKGNPVKDFEIIDNHDYSYTVKYTALQQGNMSISVTHGGDPVPKSPFNISVAPPLDLSKVKV-----QGLN-EKVEVGKDQEFTVNTQGAGGQGNVGVKMVSPSGRPIPCKLEPDRAKGVTNVKYIPPEEGQYKVDVSYDGNPVPGSPFAVEALMPADPSKVRAYGPGLKGGIVGKPAPFSIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEAGDYNINILYGEKHIPGSPFKAAVK---PALDASRVTVSGPGLERA-KAGEVATFTVDCSRAGE-AELTVEIVSDSGATAEVRIYNNNDGTFSVTYTPQSDGPYTISIRYGGQMVPKCPIRIQVEPAVDTSGVKVYGPGVEPKGVLRDVTTHFIVDARAQNKMGGNHIRVRIINPSGSNTDTHITDKGDGTYRVEYTAFEDGLHLI-EVFYDEVAVPKSPFRVSVVEGCD--PSRVRAYGPGLEGGIVNKPNCFTVETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPFHVLVRDVVDASKV-KCSGPGLGSGVRAHVPQTFTVDCSKAGLASLDVKLYGPGGATEPVAVLN----NGDGTHTVNYTPSEEGPYTVAVKYADKDVPRSPFKVHSSPAHDASKVRASGPGLDKAGVPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKASIQ--DNKDGTYTVSYVPDVTGRYTITIKYGGDQIPFSPYSIQARPTGDASKCLLSVSIGGRGVGSLGPNIQ--------MCEETVISVDAKAAGTGKVTCKVLTPDGAELDVDVVENLDGTFDIYYTAPEPGKYVITIRFGGQHIPNSPFHVQATK--EPVVPRD---------EKQPQFRPINLLIPFTVQQGALTGEVRMPSGKTARPLIRDNKDGTVTVKYAPTERGLHEMDIKYDGNHIPGSPLQFFV-DAAESGMVTAYGPGLCHG--TVNKPATFTVVTKNAAEGGLSL-----AVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDGKHIPGSPFTAKI-----------TGDD--------------SLRTSQLNVGSAADVSLKITETDLSSLTASIRAPSGAEQPCLLK-TLPNRHIGLSFTPKEVGEHEVSVKKSGKHVNNSPFKIMVGPSEIGEASRVRAFGKGLMEAHTFEVAEFFVDTRNAGYGGLGLSIEGPSKVDIKC--EDVEDGTCRVTYCPTEPGNYIINIKFAEKHIPGSPFTVKVTGEGRMKESIMRKRQAPSIASVGTICDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVHVEESTKVGGRDPFRDIFGSILGRESLGCFGSLTSKEDVQGMTAQVTSPGGKVVNAELVESGDSTYSVRFVPTEMGSHTVSVKYSGQHVPGSPFQFTVGPLGEGGPHKVRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPIATLSDDARRLTVTSLQEKDLRVYQEASFAVQRNGARGVIDAKVHSPSGVVEECYITDVDADKSAIRFIPRENGVHSIDVKFNGSHIPGSPFNVRVGETGHAGDPGLVSAYGPGLQAGCTGVPAEFVVNTCNAGSGALSVTIDGPSKAKMDCVECAEGY-KINYTPMAPGNYLISIKYGGPQHIVGSPFKAKITGVRLSGGHSLHETSSVLVETMTKSSKVAGAYSSASSSSLSSDGSRVVCQGAGLTRAFIGQKNIFTVDCSKAGTNMLMVGVHGPRTPCEDVYVKHLGNRLYNVTYTVKEKGNYVVIVKWGDETVPGSPFHVTV 2696 HSP 4 Score: 516.538 bits (1329), Expect = 1.882e-147 Identity = 505/1816 (27.81%), Postives = 790/1816 (43.50%), Query Frame = 2 Query: 2417 KVYGPGIERAKTNIE--TYFVVDCKLAGSGDIGISVLD-EKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPI-ESDNDFKKYKINNLNNTTPIGQLNE----FEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNG---FVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLIS-------ADYAIDNKAYN----KPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRT-NEKAELRKP------------NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITK--QPQKFTVDLEGAGQGGLGLSIE------GPADAQIQCFD---NKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKS--VKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAG-ESDLELMVTGPNNESVNLDVD-NHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYG--RPDMHAHFTIVTK---DAGAGGLSLAVEGPSKA--EIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIF--GEPKKRSQICVGTTSDVPLR----ISETDINNLNAIVISPTGREES-CTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQ-FVVDTRNAGYGGLSLSIEGPSKVE--IECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGP--HKVHIMGSGVERGLAN----DANQFTIYTREAGAGSLSIAIEGPSKAEIDFQ--DNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIH-----HGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 K YGPGIE + F V+ AG G++ + V D E R+ V +N + +++ F+ +I +SPF V + ++ D K + P G + + F+I T G+ +IV P G + V++ N G F + P + GPHT+ V G PI SP+KV ++ N T L AD+ + K K S+ PV+ +V ++ P Y V T +A R P V A+G GL G+ A F++++ LG +IEGP +AKI+ D GDG+C V Y P EPG Y V+V+ +DE IKDSPF I P ++N KV A+GPGL PTGV + ++FT++A+ GKG +K + + + DGT+ C Y P +H I I++ GV V SPY V V +G P +++ YGPG+E+ K +P FTVD AGQG + + I+ G A+A I FD N + T +V+Y P PG Y V + F EK IP SP+ V + D KV+ GPGL + G +V TP+ FT+ AG+A +V+ T K VK +I+ + V Y GN I V + VP SPF +V + KV V G + G FT+NT+ AG + ++ + + P+ + ++ + G +Y G Y V V Y VPGSPF V A P + GP L VGK ++T+ AG G L GP + C ++ G +VSY+P + G Y + +++ +++IP GS + A +P S T E++K E + + +V+ +V R+ NN DGT +V Y P G + + + Y GQ + P + V+ + + V YGPG+ D+ HF + + G + + + PS + + D +GT V Y G + I + + + + SPF + +P + G + + ET + ++ G E+ + K ++G + + P G + +N+ G+ IP SPF + V ++ +AS+VK G GL G+ Q F VD AG L + + GP + +N DGT V Y P+E G Y + VKYAD +VP SPF V+ +S D A V V E + + T ++ P G + I D +++ ++P G +T+++K + SP+ P D V I G GV N + ++ + AG G ++ + P AE+D +N DG+ + Y EPG YV +I+F +H+P SPF +Q + P ++ D + + N +I + + G+++ V PS K I + +V + P E G+H + + + + IPGSP + V + HG + F V T NA G L++ ++GPSK +++C++N+ G +Y+P APGDY I +K+ G HI GSPF I+G+ DS+R ++ L V + I + L+ SG +PC +K L N +++ +E G H + V+ V SPF+I+V Sbjct: 287 KAYGPGIEPEGNMVMKPAVFTVETLDAGLGEVIVYVEDPEGYREEAKVVPNNDKKRTYSVSYVPKVAGPHKVKVLFAGQDIDKSPFSVNVAKTVGDPNKVQARG-PGLEPTGNVTQRPTYFDIYTAGAGAGDVSVVIV-DPQGKKDTVEVILENKGDSVFRCTYQPVLEGPHTIHVSFAGQPIPKSPFKVHISEASNASSCRATGRGLQPKGVRVKEVADFRVFTKGAGTGELKVSVKGPGGAEVPVKVRDV----GDGVYECDYRPTVPGKYTVTITWGGQAIPRSPFEVEVGVQAGLQKVRAWGPGLKTGMVGKSADFVVEAIGTEVGSLGFSIEGPSQAKIECEDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILP----AANDVFPEKVRAFGPGLQPTGVIVNMPAEFTIDARQA---GKGELKIYAQDAEGCIIDIKITDKGDGTFVCVYVPKKPIKHTIIISWGGVNVPNSPYRVLVGEGCHPDKVKVYGPGVEKTGLKSSEPTYFTVDCGEAGQGDISIGIKCAAGVVGTAEADID-FDIIKNDNDTFTVKYTPPAPGRYTVMVLFAEKEIPSSPYKVKVEPSHDAGKVRAEGPGLNKTGVQVDTPTHFTIFTKGAGKAKPEVH-FSTGQKGNPVKDFEIIDNHDYS-YTVKYTALQQGNMSISVTHGGDPVPKSPFNISVAPPLDLSKVKVQGLNEKVEVGK------DQEFTVNTQGAGGQGNVGVKMVSPSGRPIPCKLEPDRAKGVTNVKYIPPEEGQYKVDVSYDGNPVPGSPFAVEALMPADPSKVRAYGPGLKGGIVGKPAPFSIDTKGAGAGGLGLTVEGPCEAKIEC--QDNGDGTCSVSYLPTEAGDYNINILYGEKHIP-GSPFKAAVKPALDAS-RVTVSGPGLERAK---AGEVATFTVDCSRAGEAELTVEIVSDSGATAEV-RIYNNNDGTFSVTYTPQSDGPYTISIRYGGQMVPKCPIRIQVEPAVDTSGVKVYGPGVEPKGVLRDVTTHFIVDARAQNKMGGNHIRVRIINPSGSNTDTHITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFRVSVVEGCDPSRVRAYGPGLEGGIVNKPNCFTVETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPFHVLV--RDVVDASKVKCSGPGLGSGVRAHVPQTFTVDCSKAGLASLDVKLYGPGGATEPVAVLNNGDGTHTVNYTPSEEGPYTVAVKYADKDVPRSPFKVHSSPAHDASKVRASGPGLDKAGVPASLPV-EFTIDARDAGEGLLTVQILDPEGKPKKASIQDNKDGTYTVSYVPDVTGRYTITIKYGGDQIPFSPYSIQARPTGDASKCLLSVSIGGRGVGSLGPNIQMCEETVISVDAKAAGTGKVTCKVLTPDGAELDVDVVENLDGTFDIYYTAPEPGKYVITIRFGGQHIPNSPFHVQATKEP------------VVPRDEKQPQFRPI-----------NLLIPFT-VQQGALTGEVRMPSGKTARPLIRDNKDGTVTVKYAPTERGLHEMDIKYDGNHIPGSPLQFFVDAAESGMVTAYGPGLCHGTVNKPATFTVVTKNAAEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDGK-HIPGSPFTAKITGD-----DSLRTSQ-----------------------------LNVGSAADVSLKITETDLSSLTASIRAPSGAEQPCL---LKTLPNRHIGLSFTPKEVGEHEVSVKKSGKHVNNSPFKIMV 2007 HSP 5 Score: 438.728 bits (1127), Expect = 2.624e-123 Identity = 414/1544 (26.81%), Postives = 671/1544 (43.46%), Query Frame = 2 Query: 3164 IYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPM----EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDS---FSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTV--DNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLE-EGI-TKQPQKFTVDLEGAGQGGLGLSIEGPADAQI--QCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVL---NSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKT--VTIPVNTQNAGDGILS------AKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYG--PGLSYGRPDMHAHFTIVTKDAGA-GGLSLAVEGPSKAEIQCI---DNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIF--GEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQ-----NGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSI--EGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQR-----NTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKAN----FVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGH--------TGRINEFFVDTSNAGNGALTVTIDGPSKV--QLNCQENESG-YNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMIS-GSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEI 7615 + P Q +KA+ P + G ++K PA F +++ + + V +E P EAK+ ++ T SV+Y+PK G + V VL+ + I SPF+V + + + D KV A GPGL PTG F +T A G G V +I +P ++ T V +N D + C+Y P ++G H I +++ G P+ KSP+ V + + S+ S RA G GL+ +G+ K+ F V +GAG G L +S++GP A++ + D DG Y P PG Y V+I + + IP SPF V + + KV+ +GPGL+ V + F V+A L ++ + ++ G DV Y P G+ + V+ ++ + SPF+ ++L N PEKV G G++P +I N +P+ FTI+ R AG+ +L++ +++ + + GDGTF C Y P +T+ + +G NVP SP+ V V P++ + GP + + + + V+ AG G +S A VG + I TV Y P G Y V ++F ++ IP+ + + + + T +++ F G V N +I+N D + TV+Y + G + V + G P+ SPF V + +V G + G+ FT+ T+ AG G + + + PS I C D G +V Y+P G Y + + + + GSPF + +P K G + + + I+ A E +++ +G +S+ P E G++ +N+L +HIP SPFK V +ASRV + G GL E F VD AG L++ I + + E+ ++N+DGT VTY P G Y I+++Y VP P + + + T + + E + + I+ Q + +I+PSGS I D + + + E G+H + V D V SPF+ +V D P +V G G+E G+ N N FT+ TR AGAG L + IEG S+A++ +DNKDGSC V Y PG+Y +I + + +PGSPF +++ D S G G +A+ F ++ S+ + P + ++ + ++V++ P E G + V V + +P SPF+V + + G EF +D +AG G LTV I P + + Q+N+ G Y +YVP+ G YTI+IKYGG+ I SP+ + R T ++ + +S G G P CE VDA AG + V P +V++ + F + Y E G++++ +R+G +P SPF + Sbjct: 276 VKPRQLHPKKAKAYGPGIEPEGNMVMK-----PAVFTVETLDAGLGEVIVYVEDPEGYREEAKVVPNNDKKRTYSVSYVPKVAGPHKVKVLFAGQDIDKSPFSVNV------AKTVGDPNKVQARGPGLEPTGNVTQRPTYFDIYTAGA------GAGDVSVVIVDPQGKKDTVEVILENKGDSVFRCTYQPVLEGPHTIHVSFAGQPIPKSPFKVHISEASNASSCRATGRGLQPKGVRVKEVADFRVFTKGAGTGELKVSVKGPGGAEVPVKVRDVGDGVYECDYRPTVPGKYTVTITWGGQAIPRSPFEVEVGVQAGLQKVRAWGPGLKTG--MVGKSADFVVEAIGTEVGSLGFSIEGPSQAKIE----CEDKGDGSCDVRYWPTEPGDYAVHVICDDEDIKDSPFMAHILPAANDVFPEKVRAFGPGLQPT--GVIVN-MPAEFTIDARQAGKGELKIYAQDAEGCIIDIKITDKGDGTFVCVYVPKKPIKHTIIISWGGVNVPNSPYRVLVGEGCHPDKVKVYGPGVEKTGLKSSEPTYFTVDCGEAGQGDISIGIKCAAGVVGTAEADIDFDIIKNDNDTFTVKYTPPAPGRYTVMVLFAEKEIPSSPYKVKVEPSHDAGKVRAEGPGLNKTGVQVDTPTHFTI--FTKGAGKAKPEVHFSTGQKGNPVKDFEIIDNHDYSYTVKYTALQQGNMSISVTHGGDPVPKSPFNISVAPPLDLSKVKVQGLNEKVEVGK---DQEFTVNTQGAGGQGNVGVKMVSPSGRPIPCKLEPDRAKGVTNVKYIPPEEGQYKVDVSYDGNPVPGSPFAVEALMPADPSKVRAYGPGLKGGIVGKPAPFSIDTKGAGAGGLGLTVEGPCEAKIECQDNGDGTCSVSYLPTEAGDYNINILYGEKHIPGSPFKAAV--KPALDASRVTVSGPGLERAKAGEVATFTVDCSRAGEAELTVEIVSDSGATAEVRIYNNNDGTFSVTYTPQSDGPYTISIRYGGQMVPKCPIRIQV---EPAVDTSGVKVYGPGVEPKGVLRDVTTHFIVDARAQNKMGGNHIRVRIINPSGSNTDTHITDKGDGTYRVEYTAFEDGLHLIEVFYDEVAVPKSPFRVSVVEGCD--PSRVRAYGPGLEGGIVNKPNCFTVETRGAGAGGLGLTIEGASEAKMSCKDNKDGSCSVEYVPFIPGNYDINITYGGQPIPGSPF-------------------HVLVRDVVDASKVKCSGPGLGSGVRAHVPQTFTVDCSKAGLASLDVKLYGPGGATEPVAVLNNGDGTHTVNYTPSEEGPYTVAVKYADKDVPRSPFKVHSSPAHDASKVRASGPGLDKAGVPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKASIQDNKDGTYTVSYVPDVTGRYTITIKYGGD-QIPFSPYSI-----------QARPTGDASKCLLSVSIGGRGVGSLGPNIQMCE-----------ETVISVDAKAAGTGKVTCKVLTPDGAELDVDVVENLDGTFDIYYTAPEPGKYVITIRFGGQHIPNSPFHV 1739 HSP 6 Score: 420.239 bits (1079), Expect = 1.163e-117 Identity = 232/497 (46.68%), Postives = 311/497 (62.58%), Query Frame = 2 Query: 6194 RNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXX---------XIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKS-LTQTVHMISGSTQKGP----------SKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 + TA V SP G E++ D+ +S+RF+P E+G HTVSVK +HV GSPFQFTVGPL +GGPHKV G+G++RG+A +F+I+TREAGAG LSIA+EGPSKAEI F+D KDGSCGV+Y V EPGDY SIKFN+EH+P SPF++ I + +D+R +++ +LQ++ + +A+F + +G G I A V SPS + I+ +D ++ ++ F+P ENG+H++ V N S IPGSPF V VGE +G+ G+ G TG EF V+T NAG+GAL+VTIDGPSK +++C E GY Y P APG+Y ISIKYGG HI+GSPF I+G S+ ET S L +T M S G S V C+G GL A IG++N F VD AG ++L VGV GP PCE+V +KHLGN + V Y V+EKG ++++V+WG+ VPGSPF + VP Sbjct: 2219 QGMTAQVTSPGGKVVNAELVESGDSTYSVRFVPTEMGSHTVSVKYSGQHVPGSPFQFTVGPLGEGGPHKVRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPI---------------ATLSDDARRLTVTSLQEKDLRVYQEASFAVQRNG-ARGVIDAKVHSPSGVVEECYITDVDADKSAIRFIPRENGVHSIDVKFNGSHIPGSPFNVRVGETGHAGDPGLVSAYGPGLQAGCTGVPAEFVVNTCNAGSGALSVTIDGPSKAKMDCVECAEGYKINYTPMAPGNYLISIKYGGPQHIVGSPFKAKITGVRLSGGHSLHETSSVLVET--MTKSSKVAGAYSSASSSSLSSDGSRVVCQGAGLTRAFIGQKNIFTVDCSKAGTNMLMVGVHGPRTPCEDVYVKHLGNRLYNVTYTVKEKGNYVVIVKWGDETVPGSPFHVTVP 2697 HSP 7 Score: 369.392 bits (947), Expect = 4.769e-102 Identity = 339/1211 (27.99%), Postives = 532/1211 (43.93%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSK----VTASGPGIEPVGN--EVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKK--YKINNLNNTTPIGQLNEFEILTP---FDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVI-----------ATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNG-KGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQ---GSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKF-NEKHIPGSPFTVPI--------HDIVDVS------------------------------KVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPG--LFDVTYIPENIGNCEIEVLYNNMQVPGSPF 4354 ++ +VRA GPGL+ G P FT+D +AG+G L + +L+P+G+ + I D NK+ Y+ SY+P + G Y I IK+ +IP SP+ + + GD SK V+ G G+ +G ++ T +V AG G V C +L G + V + + + F I YT E G + + + F G I +SPF V + K+ QP+ + + F V L V P + I+ Y P G + +DIKY N I SP V + + A+GPGL G V+KPA F V T N G L +++GPS+A+I C DN DG+ V+Y PT PG+Y + + D ++IP SP+ A+I D D L+ + G + +S I T + ++++A +G P ++ + +TPK G+H V V ++ SPFK+ V E G A+ ++ +G G+ A T F VD + AG G +G+S+ E V + +D DGT T Y I I F+E IP SPF V + + K+ + + +G + + + P F + + S + + T G V VE G P++ I + +KE + T + S + N + S + P E + + Q P + + P+ E V A G GL +G+A P F I + E L + +EGP +A+I + D DG+C V+Y+ +EPG Y V++ +N+EHI DSPF V I ++ DD ++T T + + + + + NG +G++ A + +P C + + + + P +G H ID+ ++G + SP+ V V + DP + AYGPGL+ G T P +F V+ AG G L ++I+GP+ A++ C + +G + Y P PG+Y +SIK+ +HI GSPF I H + + S +V C G GL R + + + FTVD SKAG L V V T P + + G L++VTY + GN + V + + VPGSPF Sbjct: 1546 DASKVRASGPGLDKAGVPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKASIQD--NKDGTYTVSYVPDVTGRYTITIKYGGDQIPFSPYSIQAR-PTGDASKCLLSVSIGGRGVGSLGPNIQMCEETVISVDAKAAGTGKVTCKVLTPDGAELDVD--VVENLDGTFDIYYTAPEPGKYVITIRFGGQHIPNSPFHVQAT--------KEPVVPRDEKQPQFRPINLLIPFTVQQ-----GALTGEVRMPSGKTARPLIRDNKDGTVTVKYAPTERGLHEMDIKYDGNHIPGSPLQFFVDAAESGMVTAYGPGLCHGTVNKPATFTVVTKNAAEGGLSLAVEGPSKAEISCKDNKDGTCTVSYLPTAPGDYNIIVKFDGKHIPGSPFTAKITGD----DSLRTSQLNVGSAADVSLK-----ITETDLSSLTASIRAP----SGAEQPCLLKTLPNRHIGLSFTPKEVGEHEVSVKKSGKHVNNSPFKIMVGPSEIGEASRVRAFGKGLMEAHTFEVAEFFVDTRNAGYGGLGLSI--EGPSKVDIKCEDVEDGTC-RVTYCPTEPGNYIINIKFAEKHIPGSPFTVKVTGEGRMKESIMRKRQAPSIASVGTICDLNLKIPGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETK----REVHVEESTKVGGRDPFRDIFGSILGRESLGCFGSLTSKEDVQGMTAQVTSPGGKVVNAELVESGDSTYSVRFVPTEMGSHTVSVKYSGQHVPGSPFQFTVGPL------GEGGPHKVRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPI------ATLSDDARRLTV-------TSLQEKDLRVYQEASFAVQRNGARGVIDAKVHSPSGVVEECYITDVDADKSAIRFIPRENGVHSIDVKFNGSHIPGSPFNVRVGETGHAGDPGLVSAYGPGLQAGCTGVPAEFVVNTCNAGSGALSVTIDGPSKAKMDCVECAEGY-KINYTPMAPGNYLISIKYGGPQHIVGSPFKAKITGVRLSGGHSLHETSSVLVETMTKSSKVAGAYSSASSSSLSSDGSRVVCQGAGLTR--AFIGQKNIFTVDCSKAGTNMLMVGVHGPRT----PCEDVYVKHLGNRLYNVTYTVKEKGNYVVIVKWGDETVPGSPF 2692 HSP 8 Score: 217.624 bits (553), Expect = 7.849e-56 Identity = 162/523 (30.98%), Postives = 241/523 (46.08%), Query Frame = 2 Query: 5531 IFGEPKKRSQI-CVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPS-------SSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVI-----SPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGG-PHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVN----EPGDYVCSIKFND-EHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAA-------------------LQDQGFN---IGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPF 6976 IFG R + C G+ + S+ D+ + A V SP G+ + L + + F P E+G H V+V SG+H+P SPF+ VG G +V+ G GL G+ +F + TR AG GGLS+++EGPSK EI D DG+C V+Y EPG Y +++K+ + ++P SPF V I +SL E+ LR A + QRN VI SPSG E C I + ++ +IRF+P+E GVH++ VK + H+ GSPF VG G P V G G++ G +F + T AG+G+LS+ I+GPSKA++D + C Y++N PG+Y+ SIK+ +H+ GSPF +I S + +++ S A Q G IG K F ++ + V P + + + N Y+V + E G + V V + +PGSPF Sbjct: 2196 IFGSILGRESLGCFGSLT------SKEDVQGMTAQVTSPGGKVVNAELVESGDSTYSVRFVPTEMGSHTVSVKYSGQHVPGSPFQFTVGPLGEGGPHKVRAGGTGLQRGIAGVPTEFSIWTREAGAGGLSIAVEGPSKAEISFEDRKDGSCGVSYIVQEPGDYEVSIKFNNEHIPDSPFIVPIATLSDDARRLTVTSLQEKDLRVYQEASFAV---------------QRNGARGVIDAKVHSPSGVVEECYITDVDADKSAIRFIPRENGVHSIDVKFNGSHIPGSPFNVRVGETGHAGDPGLVSAYGPGLQAGCTGVPAEFVVNTCNAGSGALSVTIDGPSKAKMDCVE-----CAEGYKINYTPMAPGNYLISIKYGGPQHIVGSPFKAKITGVRLSGGHSLHETSSVLVETMTKSSKVAGAYSSASSSSLSSDGSRVVCQGAGLTRAFIGQKNIFTVDCSKAGTNMLMVGVHGPRTPCEDVYVKHLGNRLYNVTYTVKEKGNYVVIVKWGDETVPGSPF 2692
BLAST of Filamin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004223.1 (pep scaffold:Pmarinus_7.0:GL476636:147693:235187:1 gene:ENSPMAG00000003806.1 transcript:ENSPMAT00000004223.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 849.736 bits (2194), Expect = 0.000e+0 Identity = 516/1386 (37.23%), Postives = 749/1386 (54.04%), Query Frame = 2 Query: 3554 FKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHI-PGSPFTVPIHDIVDVSKVKCYGPGLERNGS-------RVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIE----GPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSI-ENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPI-TGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRI-SETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGG--------------PHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFR---------XXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLT----QTVHMISGSTQ-----KGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLM 7570 +D+ S+F V+A+ I G V+ + P + +V +NHDGTY+ Y P+ G H +++TY G V +SP+ V V G DPSR+R +GPGLE G+T + F++D AG GGLGL +EGP +A + ++ +G +V+Y PG Y I + I GSPF VP+ D V+ +KV+C GPGL + R P F+VD S+AG+A L V + +P +++ ++ G+ +TY P +G + V Y VP SPF +VL + + +V V+G GV + +P+ FTI+TR+AG++ L + + P+ V + GDG F+ Y DV G Y+V V YG VPGSPF V + +C++ GP + +G+ + VN + AG G ++ + + P + + EN G ++ + + G Y + + F + IPN A + +TE +P + VV F G ++ V+ PS RK PR+I+N DGT++V + P E GLHE+++ YNG I + SP +FYVD + VTAYGPGLS+G HA FTI TKDAG GGLSLAVEGPSKAEI C DNK+GTC VSYLP APGDY I +KF +HI GSP+ A+I + + S + G+T DV LRI +TD L A + +P+GR++ C LKRL +G +GISF+PKEVGEHLV+V GRH+P+SPF++ VG +E+G+A RV+ G GL + E +F+VDTR AG+G + +S+EGPS+VE+ C D DG C V Y P EPGTY + +K+A+ +PGSPF V + G E + Q AA V+ +G+ C L L IP + + T ++ F + DN + R +P + + + H + S + + VG GG H+V+ +G + +I+ R EGP + + C V P DY S++F DEH+PGSPF+L +D + +SR ++++ L + G+ + A+F ++ +G G I A V +PS + +S+ID + + FVP ENG+H V V + + +PGSPFR V+ G G+ G TG EF VDTS AG G+L V IDGPSKV+++C E GY+F Y+P APG Y +SI YGG +HI GSP+ ++G ++ ET S + ++G K S V+ G GL A +GK+N F VD G AG +VL VGV GP PCEEV++KH G RF V Y V+E+G +LL+ Sbjct: 1138 LRDAVSEFAVDARTISRCGGDHVRCAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTA-QGPHGTREPVEVV-QAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVS---ASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLADGGPGPAIQ---IGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLAM-----------SEDISTESLRPF----HLVVPFSLRKG----HITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPSRSPLQFYVDE-MDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIREDSLRASLLSRGSTHDVSLRIPDDTDPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSMEGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLVSG--PGRQKEEVSLCQAAAPVAVVGSTCSLPLAIPVTDCTHRTLKRVASGKDFSLEGAHVRDDNCTAQRQLPPRV--------TRSGHYSVSRWLWRVGRGAAGGSDARLASPKIGETFSHRVNEGATGGVNRMNGRMGHGSIFLRGG---GGGGHTEGPFFNTGTCDAHFNSGCAVENVTPPPRDYEVSVRFEDEHIPGSPFLLTVDG---------------VCEESRRVAVSGLLESGWKVNHPASFAVHLNG-AKGRIEAKVHTPSGSVENCFVSEID--KVAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNAFTVDCGRAGSNVLLVGVLGPSVPCEEVHVKHAGGRRFAVTYAVKERGSYLLI 2464 HSP 2 Score: 441.425 bits (1134), Expect = 5.931e-125 Identity = 249/563 (44.23%), Postives = 346/563 (61.46%), Query Frame = 2 Query: 455 DSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFT----AEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV-APYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKV 2125 DS I D LKLILGL+WTLILHYSI+MP+WE +++D + K +PKQRLLGWI K+P P+ NF+ DW DG A+GALVD+CAPGLCP+W WD Q + NA+EA+ AE+ L VA +I P E+++P VDE ++MTYLSQFP A+L APL PK N A+GPG+E GN++ A F V+T NAG G + + V +P+G KE + +K+ ++ Y P + G +++ + FA I SPF V V GD KVTA GPG+EP GN G+ T+F++ T A AG G V +LD +GR+D+V+ + ++ + Y G H V+V +AG + SPF V + + + A+GRG+Q GVRV D A F+V T+ AG +D G+ E + ++V ++E Y P GP+V+ I +G I SPF V V A K++A+GPGL G+ + A F VE G + G LGFSI+GPS+A+I C D GDGS +V Y PT PG+YAVH+LCD+E++ SP+MA I ++ P +V Sbjct: 1 DSKAIVDGNLKLILGLVWTLILHYSISMPVWE----DEEDDEAKKQTPKQRLLGWIQHKLPDLPISNFSQDWKDGRALGALVDSCAPGLCPDWEIWDVHQPIDNAREAMQQAEDWLGVAQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKNAHAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACR---ASGRGLQSRGVRVGDAAGFRVLTKQAG-SDFGMC---KASGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERV 552 HSP 3 Score: 419.083 bits (1076), Expect = 4.613e-118 Identity = 497/1956 (25.41%), Postives = 796/1956 (40.70%), Query Frame = 2 Query: 1844 AFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKGPS----EAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAE---CFDVTGQ--TIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGISVL--DEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPY--KVIATDR----VNTKEYPETETPL--LISADYAIDNKAYNKPSIPVQSAKL---TPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQ---RTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIE---GPM-----EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVD----NNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPG--LEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKP---GSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGES---------DLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFP-VGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPIT-GSPFKFYVDSTIPSGQVTAYGPGLSY------------GRPDMHAHFTIVTKDAGAGGLSLAVEGP--SKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF-----------TAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGM-VNETCQFVVDTRNAGYGGLSLSIEGPSKVEIE---CHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIP-GYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHV-TGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGS-ISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXX--------XXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMIS--GSTQKGPSKPYNVKCEGDGLKVAEIGK 7405 AFGPG+ G V + A F VET N G + ++ P EA++ ++ S Y P V G + V +L ++I +SP+ + + D KVTA GPG+ SG K F + T G+ + V D G+ + + + D C Y P +PG H V V Y +P SPF VN+ EA N + G G++ + F V K AGS D G+ +E MR V G+G +Y P GP I + IP+SPF+V + ++ +K + T + + ++ ++ P+ +R+ + + V + PT G + V V C + SP+ ++ R + P + PL L A + K +P P + + + +R+ ++ + PV T+ L + GE K + ++ I PP + V I+ G M + D I N + T +V Y P G + + V ++++ ++DSPF + + P D +KV GPG+N TGV + FTV + GK + +P + +D +NHD +Y+ Y+P G + +TY G V SP+ V V D +IR G G LE G ++ + T G GQ L + P ++ C + G + + + ++ +PGSPF + + SKV+ +G GL G V P++F VD + AG L + V ++ G V+Y+P G + +L+ + VPGSPF V S E V V G GV L S ++ E D+ P++ V + + + TFTC +K+ T + + P + H KP P L + V ++ GD + A + P G S+ + G V YVP G + V++ + +P R + R H + R +D + G + +V ++ P +G TV+Y G + + Y G IT GSPF V + +V GPGL G P M F++ AG L + +GP ++ ++ + +G ++Y P G Y + +++ + + SPF ++ G S + +D + E L+ ++ P G + +G +S+ P G + V V +P SPF + G+AS+ L G + + E +V+ + AG G ++ + P ++E++ + DGT + + T+PG Y+I V++ +P SPF V S ++ LR +L++P + + T V PSG II D S+ F P E G+H + +K + H+ + SP QF V + GP V G G+ G+ FTI T++AG G LS+A+EGPSKAEI QDNKDG+C V+Y PGDY ++KF +H+PGSP+M +I E+ +L+ + GS + + TD + ++A + +PS ++ + + ++D+ Q + F P E G H V V +P SPFRV V SG G+ T EF VDT AG G++ V+++GPS+V+L+C++ E G Y P PG Y ++IK+ I GSPF V +SG Q +E SL Q ++ GST P C LK GK Sbjct: 162 AFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPF--PVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGS-DFGMCKASGEEPMRHREV-----GEGVHEFEYKPLALGPHVIT-ITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVR-YVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERVRHRPSAKPPLPGLPRAPQPLKTKTKKQP-WPFAAVTMRGNSVSDRAVIRFMYLCTDLHIRPSVALRLFVPVPMSVSTSLLVSLTRRRSRHTGES--KCFSTKVSANAISPVVVPPGDVSVGIKCAAGAMVPVDSDVHFDIIKNDNDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPS-------HDASKVRVEGPGINATGVEAAKPAHFTVYTR---GAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPLDLGKIRVEGLGTKLEMGCEQEVRVVTRGAGGRGQ--LEARLLSPTRQKVPCSSEPLAEAAAPAAAAALLETGPHRMDVTYDGHPVPGSPFLMEAVLPANPSKVRVWGEGL--RGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLE----CHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVFGPGVEKGTTFLPPPLHSSCSLSDSHSLLEPTQREEVKHIDVPTPKEKPDSTIVTILLTSR--MTFTCLFKYIKAVRLTPVLPTKLRARPS--LLSSFHQSFKPTP--PSHPALRDAVSEFAVDARTISRCGGDHVRCAV-MAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAV---ADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDP------EGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQM---FSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHA--FATGDASKCFLADGGPGPAIQIGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLAM---SEDISTESLR--------------PFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPSRSPLQFYVDEM--DGP-SVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIRED-------------------------SLRASLLSRGSTHDVSLRIPDDTDPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSMEGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKF-AEEQIPGSPFTVLVSGPGRQ-----KEEVSLCQAAAPVAVVGSTCSLPLAIPVTDCTHRTLKRVASGK 2014 HSP 4 Score: 351.673 bits (901), Expect = 2.327e-97 Identity = 433/1756 (24.66%), Postives = 703/1756 (40.03%), Query Frame = 2 Query: 1130 YIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTK--GRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAG-FADLGVNVYGPGRSLEKCQ-IKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVD-VAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIP----------VQIRDNNDGTYSC--------RYTPKIPGKH----TVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKL---AGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIG-QLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPI-GNSPYKVIATDRVNTKEYPETETPLLISAD----YAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEI------------IYPVQRTNEKAELRKPN-------VTAYGEGLVK----GV------ANTPASFIIDSTEEPPAPLGVTIEGP--MEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGL-----NPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFN-QRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQ---PQKFTVDLEGAGQGGLGLSIEGPA--DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPG-SPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSE--AKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQP---QEQYSIERTTHHYTTEQSKPIIRTEYSVVDF------KFPVGPVFDYVRAVV---NCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISE-----TDIN----NLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGE-NEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYAD-SNVPGSPFAVNIGG 6082 Y P G + I++ F+ E+ +SPF ++V + D SKV GPGI G E + F V+T AG +D D + + +I + + ++YT ++G + V + G + SPF V V+ D + G G + E + E +V T AG L + P R C + GP+ +D+ Y +P+ SPF ++ V P SK++ +G GL GG V PA F V+T G LG +++GP EA+++C D+GDG+ +V+Y P GEYAV+IL D ++P SP+ A ++ + V +GPG+ G + P + + + +V +P V I + T++C R TP +P K +++ S+ P P P + A + F VD + G + +V+ DN DGT+ ++ + +++ ++ A +P+SPF+V + D + +++ + + N F I T G + V+ P + V + ++ GF + G + + G I SP+ V D VN + + L +SA A+ A S+ A ++ T P+ R E + + + P + A P+ + AY G V+ GV A+ P F ID+ E APL +TI P + +D GDG SV+YLP G Y V V Y + + SPF V + +S + GPG PT V VNAK G+G V + P + V+N DGT+S ++ G + I + + G + SP+ V + E I+ + P V +G + + P+ A + DN+DGT SV + P + G +++ IK+N HIP SP + D +D V YGPGL V + FT+D AGE L + V + +K+ Q + G V+Y+P G+ I V + +PGSP++ + ++ G H ++ ++P D + L + P+ + DG + G + V V G ++VP SPF V V + + G L E + V+T+ AG G + GP + V E+ G V Y P + G Y + + F +E IP P +E+ S+ + S + V D + G F A V NC + R+ PR+ +G +++ G P G F V+ G G H +I + G EGP C + N C V + P DY + ++F D+HI GSPF + G ++ ++ V + +++ +N + A V +P+G E+C + + + F P+E G H V+V G +P SPF++ VGE +A+ V +G GL G +FVVDT AG G L+++I+GPSKV ++C + +G Y PT PG Y++++ Y ++ GSP+ + G Sbjct: 701 YTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPSH-DASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPL---DLGKIRVEGLGTKLE---MGCEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCSSEPLAEAAAPAAAAALLETGPHRMDVTYDGHPVPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSG---VQVFGPGVEKGTTFLPPPLHSSCSLSDSHSLLEPTQREEVKHIDVPTPKEKPDSTIVTILLTSRMTFTCLFKYIKAVRLTPVLPTKLRARPSLLSSFHQSFKPTPPSH----------------PALRDAVSE----FAVDARTISRCGGDHVRCAVMAPSGITTEGSVTDNHDGTY-AVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGL-GLHVEGPGEAHVAFE-EDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALD----VTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCF-----LADGGPGPAIQIGEPTLVL--------VNAKE---AGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLA---------------MSEDISTESLRPFHLVVPFS-LRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPSRSPLQFYV-DEMDGPSVTAYGPGLSHG--MVGKHAAFTIDTKDAGEGGLSLAV-EGPSKAEISCQ---DNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIREDSLRASLLSRGS------THDVSLRIPD-------DTDPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSMEGP--SRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLVSGPGRQKEEVSLCQAAAPVAVVGSTCSLPLAIPVTDCTHRTLKRVASGKDFSLEGAHVRDDNCTAQRQLPPRVTRSGHYSVSRWLWRVGRGAAGGSDARLASPKIGETFSHRVNEGATGGVNRMNG---------RMGHGSIFLRGGGG---GGHTEGPFFNTGTCDAHFNSGCAVENVTPPPRDYEVSVRFEDEHIPGSPFLLTVDGVCEESRRVAVSGLLESGWKVNHPASFAVHLNGAKGRIEAKVHTPSGSVENCFVSEIDK--VAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFC-YLPTAPGLYLVSICYGGPHHIAGSPYRARVTG 2350 HSP 5 Score: 342.428 bits (877), Expect = 1.471e-94 Identity = 313/1149 (27.24%), Postives = 507/1149 (44.13%), Query Frame = 2 Query: 929 TNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVK----PKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRD-VAEFQVHTED---AGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE-SKIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPK-SPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAEC-------FDVTGQ-----TIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNE--FEILTPFDGSKVRPEIIVKSPNGSRVPVKLQE--TNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIA-TDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRS-NFEPNEEIIY---------------PVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVK 4231 N +VR +G GL G +G PA F VDT AG G L + V P + C + + S SY+P GEY + I FA++ +P SPF VK PS T+ G++ G V + T F + D L +++ VK P ++ ++ + T + + V++ + + + S Q++ + P +RD V+EF V G + V P + + Y Y+P GP+ V++ Y + SPF V VA + S+++ GPGL GG+ + F ++T G LG ++GP EA + ++ +G V Y PGEY HI I SP+ ++ + +P KV GPGL G+S +V AG+P +C DVT Q PV++ DG ++ YTP + G +++ V Y ++P SPF V+V+ A +A ++V G G+ + ++ T F +D + AG + I+++D D GDG F++ Y P G + + E+P SPF V + D K + + P Q+ E ++ + + + V +P + V + E + F FT T GP+ + V G I NSP+ V+A ++ ++T E+ P + +++ K + + + S + +++ + N + S +F P E+ ++ P+Q + E+ P+VTAYG GL G+ A+F ID+ + L + +EGP +A+I DN DGTCSV+YLP PG Y + V + +HI SP+ I D+ +S + S V+ + D ++ A I P ++ C + DG S+SP G+H + + G V SP+ V V + D R+RA G GLEE T + +F VD AG G + +S+EGP+ ++ C D +DG C V Y P +PG+Y ++IKF E+ IPGSPFTV + GPG ++ + + PL + V D +++K Sbjct: 930 ANPSKVRVWGEGLR--GGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECH----DHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVK-----PSVETS---GVQVFGPGVEKGTTFLPPPLHSSCSLSDSHSLLEPTQREEVKHIDVPTPKEKPDSTIVTILLTSRMTFTCLFKYIKAVRLTPVLPTKLRARPSLLSSFHQSF---KPTPPSHPALRDAVSEFAVDARTISRCGGDHVRCAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEV---NPAKVRCSGPGL--GLSAG---GGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVA-VGYGTDEVPGSPFPVHAFATGDASKCFLAD-GGPGPAIQIGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLAMSEDIST----ESLRPFHLVVPFSL-RKGHITGEVHMPSGR-----KASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPSRSPLQFYVD--EMDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIREDSLRASLL--------------------SRGSTHDVSLRIPDDTDPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSMEGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLVS-----------GPGRQKEEVSLCQAAAPVAVVGSTCSLPLAIPVTDCTHRTLK 2008 HSP 6 Score: 241.891 bits (616), Expect = 5.705e-64 Identity = 315/1352 (23.30%), Postives = 549/1352 (40.61%), Query Frame = 2 Query: 1394 ITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCL-----------YECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP---YKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVP---GEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPS---TVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVT-DDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKV---PIESDNDFKKYKINNLNNTTPIGQLNEFEI----LTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNG-FVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEY----PETETPLLISAD-YAIDNKAYNKPSIPVQ----SAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIY-------------PVQRTNEKAELR--KPNV-TAYGEGLVKGV-ANTPASFIIDSTEEPPAPLGVTIEGPMEAK--IDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAY----GPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQ---CFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDAS-KAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYV 5254 I K + ++YT G ++ VFF+ +++ SPFG+ V + DA + G GI GV A F V+T AG A+L V E ++ P L Y Y P + G + + YG + + SPF V VAP + +++ G L G + G G L + P+ K+ C A G + + + D +P SP++ + L +P KV +G GL G PA+F V+T AG TV+ C ++ D+ DGT S Y P G++ V + + + ++P SPF V + + ++V+GPG+E+ T + C L+ S + E+++ + V T + D T T + + P P K+ P + + +K ++ ++EF + ++ G VR V +P+G + + ++G + + P+ GPH V V G + SP++V D + P E L A+ ++ID +A + + E F+ S E I Y PV+ A++R P + + G G+V V A P F +D + A L VT +GP + ++ + DG ++ Y P G Y ++V Y + + SPF V + D +V G G++ +GV + FT++ + G + I +P V + DG +S SY P V G++ + + Y V SP+ V + D S+ GP ++ G +P V+ + AG+G + + P ++ + DGT S+ + +PG Y ++++F + IP SPF V + D+S + P V S + G +V++ + + P I + G V++ P G E+++ YN +P +Q ++ + V G G+ H + K + FTI+T+DAGE L L V GP+ ++ DN DGT + Y PG+Y++ V + +++PGSP++ + ++ G + ++ IP +T A +L+A P G C ++ G +S+ P+++G + V + ++P+ R + + E+++ E+ +VD ++ F + + PS R ++ + DG V Y P E G + L + + + I GSPF V Sbjct: 689 IIKNDNDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDV---VPSHDASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAELDVQ-------FEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPLDLGKIRVEGLGTKLEMG-CEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCSSEPLAEAAAPAAAAALLETGPHRMDVTYDGHPVPGSPFLMEAVLPA---NPSKVRVWGEGLRGG-EVGIPAEFCVDTTAAGVGGLGLTVEGPC------EARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVFGPGVEKGTTFLPPPLHSSCSLSDSHSLLEPTQREEVKHIDVPTPKEKPDSTIVTILLTSRMTFTCLFKYIKAVRLTPVLPTKLRARPSLLSSFHQSFKPTPPSHPALRDAVSEFAVDARTISRCGGDHVR--CAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVL-------AAYDAGRVRVSGAGVSASGVPASLPTDFTIDTRE---AGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLADGGPGPAIQIG---EPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHV-LAMSEDIS-------------TESLRPFHLVVPFSLRKGHITGEVHM--PSGRKASPRII--DNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPSRSPLQFYVDEMDGPSVTAYGPGL----SHGMVGK-HAAFTIDTKDAGEGGLSLAVEGPSKAEISCQ-DNK-DGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIREDSLRASLLSRGSTHD-----VSLRIPDDTDPA---LLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEF-IVDTRY---AGFGSMCVSMEGPS-RVEL-HCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLV 1965 HSP 7 Score: 201.445 bits (511), Expect = 1.266e-51 Identity = 215/859 (25.03%), Postives = 362/859 (42.14%), Query Frame = 2 Query: 5357 GAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFG--EPKKRSQICVGTTSDVPLRISETDINNLNA------IVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHI-PNSPFKIFVGENEIGNASRVKLYGDGLN----DGMVNET-----CQFVVDTRNAGYGGLSLSIEGP--SKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNI-GGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASV--ISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPF---QFTVGP-----LIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDF---QDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPF-MLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPG-SPFR-----XXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQS---------NDSIR-----ETKSLTQTVHMISG-----------------------------STQKG----PSKPYNV-------------KCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 G + AV PS E DN +GT V Y+P + G + + + + + SPF + +P + G + R + I+ A + + G E + G + + GE+L ++ G I SPF + V +E+ N ++V+ G GL G+V F VD AG L ++ +GP ++ +E DG +TY P+ G Y ++V+YA +VP SPF V++ Y + R+ S + + I + S+ + P G ++ D FS+ ++P G ++V+V V GSPF F G L DGGP G ++ G + + +EAG G ++ + P + E+D ++ DG+ + + +PG YV +++F + +P SPF +L + E+ + +P + V+ + L G I+ V PS ++ I + SV F P+E G+H + + N IP SP + + VT G G+ HG G+ F +DT +AG G L++ ++GPSK +++CQ+N+ G + +Y+P APGDY+I++K+ G HI GSP+ I ++ ++ + S+R + LT + SG S ++G PS P+ V + G GL+ A + EFIVD AG + V + GP R E++ + L + R +V Y E G + L +++ +PGSPF ++V Sbjct: 1156 GGDHVRCAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPG-EAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPV-RDEV-NPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAG----RVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLADGGP------GPAIQIG---EPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLAMSEDISTESLRPF-----------------------------HLVVPF-SLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPSRSPLQFYVDEMDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQ-HIPGSPYMARIREDSLRASLLSRGSTHDVSLRIPDDTDPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSMEGPSR--VELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLV 1965 HSP 8 Score: 151.369 bits (381), Expect = 1.889e-36 Identity = 222/894 (24.83%), Postives = 340/894 (38.03%), Query Frame = 2 Query: 5084 VRAVVNCPSNRKDVPRLI--NNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTI-PSGQVTAYGPGL--SYGRPDMHAHFTIVTKDAGAGGLS-------LAVEGPSKA-EIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKI-----------FGEPKKRSQICVGTTS--DVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALS-DNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEG----PSKAEIDFQDNKDGSCGVTYRVNEP--GDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISK--IDNNQYS--VHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG-----HTGRINEFFVDTSNAG-NGALTVTIDGPSKVQLNCQENESGYNFTYVPNAP----GDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCE-EVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 V V P K+ R+ N+ + Y+P +G H++ V + GQ I SPF V +G+VTA GPG+ S +F I T GAG L G A E+ ++ +Y PL PG + + + + + SPF+ I G + + VG + V + + +D A EE + + G + P +G H++ + G+HIP SPF++ V +V+ +G GL GM + FVV+ G L SIEGPS+ I C D DG+C V Y PTEPG Y ++V + +V SPF +I ER+ RH+ +A+ G +P Q T + P F + S ++ IRFM +H + R P + L+ + G AN + G S+ I P +++ F K+ + +T + P G + + F+++ V SPF ID P SK V+ E N + G A+F + G + P + + IDN+ YS V + P + G + V +PGSPF V V G+ G G E V T AG G L + P++ ++ C A G + + + Y G+ + GSPF L + V P+ P V+ G+GL+ E+G EF VD AG L + V G PCE + G+ V+Y + G + + + + + VPGSPF VV Sbjct: 192 VLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSDFGMCKA------SGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAE--AGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERV-RHRPSAKPPLPG--------LPRAPQPLKTKTKKQPW-PFAAVTMRGNSVSDRAVIRFMYLCTDLH-IRPSVALRLFVPVPMSVSTSLLVSLTRRRSRHTGESKCFSTKVSANAISPVVVPPGDVSVGIKCAAGAMVPVDSDVHFDIIKNDNDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPF--GIDVVPSHDASK-VRVEGPGINAT-----------GVEAAKPAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPLDLGKIRVEGLGTKLEMGCEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCSSEPLAEAAAPAAAAALLETGPHRMDVTYDGHP-VPGSPF--------------------LMEAVL---------PANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEG---PCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVV 1019 HSP 9 Score: 135.961 bits (341), Expect = 1.002e-31 Identity = 123/418 (29.43%), Postives = 180/418 (43.06%), Query Frame = 2 Query: 1190 PNSPF--KVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGV----NVYGPG--RSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVA-PYKESKIKAFGPGLT--GGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIR----DNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEA 2398 P +P K+N KNA A GPG+E VGN V R F V T AG G V + D +G K+ + + F+ Y + G H V V FAG I SPF V+V+ + DA + A G G++P G F + T G V P R + +++ + C+Y P PGP++V + Y + SPF+V++ +A G GL G V A F V T G K E + + G+G Y P G + + I ++IP+SP+ + + P KV A+GPGL +G++ + ADF+V + V F + G P Q R D DG+ RY P PG + V V ++ SPF +++ A Sbjct: 147 PGAPLRPKLNPKNA-------HAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPP--HGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSDFGM-CKASGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEA---GPQKVRAWGPGLETGMA-GRSADFVVEAIG----TDVGTLGFSIEG---PSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPA 543 HSP 10 Score: 116.701 bits (291), Expect = 5.524e-26 Identity = 107/374 (28.61%), Postives = 164/374 (43.85%), Query Frame = 2 Query: 1544 KQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQI-----KKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP--YKESKIKAFGPGL--TGGIVSKPAFFEVET-------------------NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLIS-GISTNKPADFIVNTKNAGSP-STVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGT 2575 K A+A G G++ G V AEF V TE+AG ++ V V P E+ ++ K+ S + Y P+ GP+ V + + I SPF V VAP K+ A GPG+ +G + K +F++ T G A+ +++ +A + C TY P VPG + V + +P SP+ I + +P A G GL S G+ A F V TK AGS KA +G+ P++ R+ +G + Y P G H + +++G +IP SPF+V V ++ +GPG+E FVV+ G +G S+ E + DD GDG+ Sbjct: 158 KNAHAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRS---FVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRC----------TYRPLVPGPHIVSVGYAGAAVPHSPFSVNIG---EACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSDFGMCKA-----SGEE-PMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSI--EGPSQARIACDDRGDGS 507 HSP 11 Score: 116.316 bits (290), Expect = 8.696e-26 Identity = 111/416 (26.68%), Postives = 180/416 (43.27%), Query Frame = 2 Query: 3191 KAELRKPNVTAYGEGLVKGVANT---PASFIIDSTEEPPAPLGVTIEGPM----EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTV-NAKPIDFNGKGIVKAIITNPFNQRSTC--TVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITK--QPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVL---NSCEPEKV 4393 + +L N A+G G V+ V N+ A F++++ + V +E P EA++ ++ + Y P+ G + V VL+ +HI SPF V + P D KVTA GPG+ P+G + F + A G G V + +P +R T++ D C+Y P V G H + + Y G V SP+ V + + +P RA G GL+ + F V + AG G+ + + ++ + +G +Y P G + ++I + KHIP SPF V + KV+ +GPGLE + F V+A L ++ + + G DV Y+P G+ + VL + V SPF+ ++L C PE+V Sbjct: 152 RPKLNPKNAHAFGPG-VEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPH------GDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGS-DFGM-CKASGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETG--MAGRSADFVVEAIGTDVGTLGFSIEGPSQARIA----CDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERV 552 HSP 12 Score: 113.62 bits (283), Expect = 4.787e-25 Identity = 117/450 (26.00%), Postives = 191/450 (42.44%), Query Frame = 2 Query: 3710 PAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEE--GITKQPQKFTVDLEGAGQGGLGLSIEGPA----DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTV---PIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTV----DASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKP 5020 P VD +H + P AK P+ +P A+GPG+E ++ +F V+ E AG G + + +E P +A++ ++K + Y P+ G + V++ F +HI SPF V P H D KV GPG+E +G+ + F + D + AG + V V+D + L + + TY P G + V Y VP SPF N+ +C P +G G++ RG + + + F + T+ AG SD + + +V G+G +YK G + + + +G K++P SPF V V +EA P++ GP L G++ V G L GP + C + G V YVP + G Y V ++ ++E++ + ER H + + P Sbjct: 126 PNVD-EHSVMTYLSQFPKAKLKPGAPLRPKLNPKNAHAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHG--DAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQ-SRGVRVGDA--AGFRVLTKQAG-SDFGMCKASGEEPMRHREV---GEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGD--GSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERVRHRPSAKPPLP 563 HSP 13 Score: 96.6709 bits (239), Expect = 7.704e-20 Identity = 187/840 (22.26%), Postives = 314/840 (37.38%), Query Frame = 2 Query: 5285 AYGPGLSY--GRPDMHAHFTIVTKDAGAGGLSLAVEGPS----KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF---TAKIFGEPKKRSQICVGT--TSDVPLRISETDI-----------NNLNAIVISPTGREESC--TLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAG--YGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGD-------YVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSIS------AYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG--------HTGRINEFFVDTSNAGNGALTVTIDGP---SKVQLNCQE----NESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEF-IVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPF--EIVVP 7624 A+GPG+ + A F + T++AG G + + VE P +A + ++K + Y P G + + + F +HI SPF A G+ K + G + +V + + DI ++ V+ P GR ++ TL++ ++ L ++ P G H+V+V +G +P+SPF + +GE A R G V + F V T+ AG +G S E P + + +G YKP G ++I + + ++P SPF V + + + +++ E G + + G + S+ PS + C+ D +R++P E G + V V D V SPF HI+ + + D + R + L P + + VT R N D Y+C+ D H+ S + P S + +++ + +R S + + F+ AN I+ + G +S A + P + + I K DN+ +V + P G + V + + SPF + V + + G + F V T AG L V + P + V + E ++ Y Y P G + + YGG+ H+ GSPF V ++ P ++ EG G K+ E+G E +V G G L + P R PC + + E G H + V + H VPGSPF E V+P Sbjct: 162 AFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSDFGMCKASGEEP----MRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVS---AEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACD--DRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFM-------------AHILPA------SRDCFPERVRHRPSAKPPLPGLPRAPQPLKTKTKKQPWPFAAVTMRGNSVSDRAVIRFMYLCT----DLHIRPSVALRLFVPVPMSV------STSLLVSLTRRRSRHTGESKCFSTKVSAN-AISPVVVPPGDVSVGIKCAAGAMVPVDSDVHFDIIKNDNDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPSHDASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGD-HVPGSPFPVTVAP-----------------------------PLDLGKIRVEGLGTKL-EMGCEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCSSEPLAE--AAAPAAAAALLETGPHRMDVTYDGHPVPGSPFLMEAVLP 929 HSP 14 Score: 95.1301 bits (235), Expect = 2.315e-19 Identity = 95/327 (29.05%), Postives = 140/327 (42.81%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPK-GQKEP---CEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEA-GPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDV---AEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE-SKIKAFGPGLTGGIVSKP 1885 ++ +VR GPG+ G PA FTV T AGK LD+ +P+ G P EI D N + +Y+ Y P +G + + + +P SPF V V D K+ G G + E+G V T A G G ++ +L +K E G H ++V + G + SPF +M + +N + + EG+R +V AEF V T AG LG+ V GP + +C C SY+P + G Y V+I + + + SPF V P E S ++ FGPG+ G P Sbjct: 734 DASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIID--NHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPL-DLGKIRVEGLGTK---LEMGCEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCS-SEPLAEAAAPAAAAALLETGPHRMDVTYDGHPVPGSPF-LMEAVLPANPSKVRVWG-------EGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTC--SVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVFGPGVEKGTTFLP 1043 HSP 15 Score: 75.0998 bits (183), Expect = 2.786e-13 Identity = 71/247 (28.74%), Postives = 102/247 (41.30%), Query Frame = 2 Query: 1151 EYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIE-------YTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGLTGG 1870 +Y + ++F + IP SPF + V + +V SG + G +V F V A KGR ++ + EN F+ E + +E G+H V+V G + SPF V V +DA A G G+ E AEF V T AG L V + GP + C P Y Y+P PG Y+V I YG P ++ +PY+ + GP L+GG Sbjct: 2138 DYEVSVRFEDEHIPGSPFLLTVDGVCEESRRVAVSG--LLESGWKVNHPASFAVHLNGA------------KGRIEAKVHTPSGSVENCFVSEIDKVAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGL--ERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCS---EGPEGYHFCYLPTAPGLYLVSICYGG------PHHIAGSPYRA---RVTGPRLSGG 2356 HSP 16 Score: 66.6254 bits (161), Expect = 9.071e-11 Identity = 54/210 (25.71%), Postives = 97/210 (46.19%), Query Frame = 2 Query: 3125 NKQRSNFEPNEEIIYPVQRTNEKA---------ELRKPN-------VTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYND-EHIKDSPFNVTIY-PDTKSSSNIDDVAK--VTAYGPGLNPTGVFKDSFS-KFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGT 3691 +K + F P E ++PV T + A + +P V+A+G GL +G +PA F++D++ P L V I+GP + ++D + +G YLP PG Y+V++ Y HI SP+ + P N+ + + V A P G+ + K T ++ ++ +G G+ A++ +++ TVD G+ Sbjct: 2218 DKVAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEGY-HFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALV----GKQNAFTVDCGRAGS 2422 HSP 17 Score: 66.2402 bits (160), Expect = 1.269e-10 Identity = 89/346 (25.72%), Postives = 149/346 (43.06%), Query Frame = 2 Query: 2057 NIPKSPYMAQIQLDTKLFDPLKVTAYGPGLIS-GISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDG--TYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEA-GNAANIKVYGPGIERAK--TNIETYFVV----DCKLAGSGDIGISVLDEK-MRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNL---NNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVA-GFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEY----PETETPLL-ISADYAID 3034 PK+ L KL +P A+GPG+ + G S + A+F+V T+NAG V D G ++ ND ++ Y P++ G H V V + +I SPF V V G+A + GPG+E + TYF + D AG GD+ ++VLD + RD +T + + + + ++ A +P SPF V I + + + + +G F +LT GS + + +G P++ +E G + P +GPH +T+ G I SP++V+ + ++ P ET + SAD+ ++ Sbjct: 139 QFPKAKLKPGAPLRPKL-NPKNAHAFGPGVEAVGNSVERAAEFVVETENAGL-GEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGS----DFGMCKASGEE-PMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVE 477 HSP 18 Score: 61.6178 bits (148), Expect = 3.033e-9 Identity = 105/444 (23.65%), Postives = 168/444 (37.84%), Query Frame = 2 Query: 4523 NESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEV--PVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSI--ENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPII--RTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLI--NNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGL-SYG-RPDMHAHFTIVTKDAGA--GGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGE--PKKRSQI-------CVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFV 5791 E V+ +VD H T+ Q+ K PG+P + P+ + GP + V V + V T+NAG G + P G+ + N++ Y P+ G ++V ++F ++I + S P + + T E S + T + + G V V P R+D + D + Y+P G H + V Y G + SPF + G A G GL S G R A F ++TK AG+ G + E P + + G + Y PLA G + I I + KHI SPF + E P+K G ++D + TD+ L + P+ +C + +G + + P E G++ V+VL + SPF + Sbjct: 121 EEIVDPNVDEHSVMTYLSQFPK-------------AKLKPGAPL----RPKLNPKNAHAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHI-DRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSDFGMCKASGEEPMRHR----EVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDR--GDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHI 540 HSP 19 Score: 57.7658 bits (138), Expect = 4.234e-8 Identity = 100/430 (23.26%), Postives = 156/430 (36.28%), Query Frame = 2 Query: 6392 PHKVHIMGSGVERGLAND---ANQFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQI-----DENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLA--SISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGH--------TGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVS--GPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPF 7609 P H G GVE + N A +F + T AG G + + +E P +A + +++K S YR G + ++ F +H+ SPF + + D ++ V+ + + Y I D V+ P + ++ + + + P+ G H V V + +P SPF V +GE G G G F V T AG+ G ++ + E + F Y P A G + I+I +GG HI SPF V +S + GP K V+ G GL+ G+ +F+V+A G DV +G S GP + + G+ V Y E G + + V DV SPF Sbjct: 157 PKNAHAFGPGVE-AVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVT--------------VLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSDFGMCKASGEEPMRHR-EVGEGVHEFEYKPLALGPHVITITWGGK-HIPRSPFEVLVS--------------------------AEAGPQK---VRAWGPGLETGMAGRSADFVVEA--IGTDVGTLGFSIEGPSQ--ARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPF 536 HSP 20 Score: 56.6102 bits (135), Expect = 1.040e-7 Identity = 57/191 (29.84%), Postives = 86/191 (45.03%), Query Frame = 2 Query: 962 GLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNA--AGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILD--TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGV-QIQSSPFGVMVS 1519 GL G + +PA F V N KG ++ V P G E C F S ++A ++P G + + + + +P SPF+V V A D + V+A GPG+E G F V T+ AGPGS+ V +D +K R D + + Y GL+ V++ + G I SP+ V+ Sbjct: 2173 GLLESGWKVNHPASFAVH-LNGAKGRIEAKVHTPSGSVENC--FVSEIDKVA--ARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLE--RGTTGSPAEFVVDTSGAGPGSL-AVAIDGPSKVRVD------CSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVT 2349 HSP 21 Score: 51.9878 bits (123), Expect = 2.747e-6 Identity = 55/212 (25.94%), Postives = 80/212 (37.74%), Query Frame = 2 Query: 929 TNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFAN-SEIPNSPFKVNVKN-----------------AAGDP--------------------SKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEG 1450 ++ V A+GPGLE T G+PA F VDT AG G+L + + P + C + P Y Y+PT G Y + I + I SP++ V AG+P SKV + GPG+ VG++ F V AG + +L + V + +F + Y KE G Sbjct: 2259 ADAALVSAFGPGLER--GTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCS--EGPE---GYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTA--LVGKQNAFTVDCGRAGSNVLLVGVLGPSVPCEEV--HVKHAGGRRFAVTYAVKERG 2459
BLAST of Filamin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004195.1 (pep scaffold:Pmarinus_7.0:GL476636:147693:235244:1 gene:ENSPMAG00000003806.1 transcript:ENSPMAT00000004195.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 625.55 bits (1612), Expect = 0.000e+0 Identity = 372/966 (38.51%), Postives = 533/966 (55.18%), Query Frame = 2 Query: 3482 KSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHI-PGSPFTVPIHDIVDVSKVKCYGPGLERNGS-------RVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIE-----------------GPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSI-ENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIR------------------QYAFQP---------QEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPI-TGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIF-GEPKKR-SQICVGTTSDVPLRI-SETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTA 6208 K + + K ++ P +P +D+ S+F V+A+ I G V+ + P + +V +NHDGTY+ Y P+ G H +++TY G V +SP+ V V G DPSR+R +GPGLE G+T + F++D AG GGLGL +EGP +A + ++ +G +V+Y PG Y I + I GSPF VP+ D V+ +KV+C GPGL + R P F+VD S+AG+A L V + +P +++ ++ G+ +TY P +G + V Y VP SPF +VL + + +V V+G GV + +P+ FTI+TR+AG++ L + + P+ V + GDG F+ Y DV G Y+V V YG VPGSPF V + +C++ GP + +G+ + VN + AG G ++ + + P + + EN G ++ + + G Y + + F + IPN Q P +E + + + + S +R + VV F G ++ V+ PS RK PR+I+N DGT++V + P E GLHE+++ YNG I TGSP +FYVD + VTAYGPGLS+G HA FTI TKDAG GGLSLAVEGPSKAEI C DNK+GTC VSYLP APGDY I +KF +HI GSP+ A+I GE R S + G+T DV LRI +TD L A + +P+GR++ C LKRL +G +GISF+PKEVGEHLV+V GRH+P+SPF++ VG +E+G+A RV+ G GL + E +F+VDTR AG+G + +S+EGPS+VE+ C D DG C V Y P EPGTY + +K+A+ +PGSPF V + G E + Q AA V+ +G+ C L L IPG N TA Sbjct: 1118 KQKTTTTSITKASSQAPPSHPA--LRDAVSEFAVDARTISRCGGDHVRCAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTA-QGPHGTREPVEVV-QAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVS---ASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQ---IGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLTHPAAGGRGLCERELWRAPSESIAMSEDISTESLRPFHLVVPFSLRKG----HITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDE-MDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGEDSLRASLLSRGSTHDVSLRIPDDTDPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSMEGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLVSG--PGRQKEEVSLCQAAAPVAVVGSTCSLPLAIPGNELFNCTA 2066 HSP 2 Score: 477.248 bits (1227), Expect = 5.004e-136 Identity = 410/1544 (26.55%), Postives = 679/1544 (43.98%), Query Frame = 2 Query: 3299 APLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPV-AKSPYFVPVYQGSDPSRIRAYGPGLEEGITK-----------QPQKFTVDLEGAGQGGLGLSIEGPADAQ--IQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGE-------GVRPHRGHLIANKV--PSLFTINTRDAGESDLELMVTGPNNESVNLDV-DNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIV-----PVHSEAKP---------------------------EQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIER----TTHHYTTEQSKPIIRT-EYSVVDFKFPV-GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNK--NGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKI----FGEPKKRSQICVGT----TSDVPLRISETDINNLNAIVIS---PTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKEL-GVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPG-----DYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSV---HFVPVENGIHNVHVLVNNSPIPGSPFR---------XXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLT----QTVHMISGSTQ-----KGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 AP G+T EG + DN DGT +V Y+P G + V V Y + SPF V + ++ D ++V +GPGL G + F+++ + G G+ + P + + + +G ++ Y G++ ITY G + A SP+ VPV +P+++R GPGL G++ PQ F+VD AG L ++ +GP + ++ DG ++ Y P G Y + +++ + +P SPF V + D +V+ G G+ +G P+ FT+D +AG+APL + ++D + A++L GLF V+Y+P+ G + V Y +VPGSPF + + + K + GV G A ++ P+L +N ++AG + V P +++DV +N DGTF+ + PG Y + V +G + +P SPF V P+ +P E + I E + +P + + G ++ + P G I + R G +VS+ P + G +E+ + +N +IP GS Q+ + S+ +H + + I T + V GP +A ++C N+ DGT +V Y P+ G + + V + GQ I GSP+ + I +G+ + LS G H + D L+ + PS + C+ + +G +S+ P G++ + ++ +H+ SPF + G+ ++ +G T + I +T ++ +S P+ E C + L++G + + P E G + + + + IP SPF + V V L +V TC + + + P +V H + + G+ + + A + G F + GG + C+ P T I + +++ L Q S F+ + + H+V+ K+ ++ V + T + +GG KV + G R +F +T + GA + S+ ++ + D V RV++ DY S++F DEH+PGSPF+L +D + +SR ++++ L + G+ + A+F ++ +G G I A V +PS + +S+ID +++S+ FVP ENG+H V V + + +PGSPFR V+ G G+ G TG EF VDTS AG G+L V IDGPSKV+++C E GY+F Y+P APG Y +SI YGG +HI GSP+ ++G ++ ET S + ++G K S V+ G GL A +GK+N F VD G AG +VL VGV GP PCEEV++KH G RF V Y V+E+G +LL+V+WG+ VPGSPF + VP Sbjct: 1168 APSGITTEGSV------TDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAV-------ADGCDPSRVRVHGPGLE--GGLTHRANVFSIDTRAAGCGGLGL---HVEGP--GEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGL--GLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRR-ARVL-DGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQIGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLTHPAAGGRGLCERELWRAPSESIAMSEDISTESLRPFHLVVPFSLRK---GHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEMDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPS----KAEISCQDNK----------DGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYM----ARIIAGEDSLRASLLSRG--STHDVSLRIPDDTDPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSMEGPSRVELHC--EDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLV-SGPGRQKEEVSLCQAAAPVAVVGSTCSLPLAIPGNELFNCTAQRQLPPRVTRSGHYSVSRWLWRVGRGAAGGS---DARLASPKI-GETFKIYNGG-------------TRGGCCGAVTKYCQREPAEPSMAHEGT----IPQAACIHASDLLKLKAGQGSYPFVTELMCSKHSVTYKASSQRVAVCKDRRTSRLVGNGGHRKVRLWGVSPSRATQPVCTRFYFWTHKKGARASSVDVDCVALNSFAVHDRLH----VDKRVSQTKNGINRDYEVSVRFEDEHIPGSPFLLTVDG---------------VCEESRRVAVSGLLESGWKVNHPASFAVHLNG-AKGRIEAKVHTPSGSVENCFVSEIDKDKWSLLAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNAFTVDCGRAGSNVLLVGVLGPSVPCEEVHVKHAGGRRFAVTYAVKERGSYLLIVKWGDQHVPGSPFRVTVP 2620 HSP 3 Score: 448.358 bits (1152), Expect = 5.110e-127 Identity = 251/563 (44.58%), Postives = 348/563 (61.81%), Query Frame = 2 Query: 455 DSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFT----AEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV-APYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKV 2125 DS I D LKLILGL+WTLILHYSI+MP+WE +++D + K +PKQRLLGWI K+P P+ NF+ DW DG A+GALVD+CAPGLCP+W WD Q + NA+EA+ AE+ L VA +I P E+++P VDE ++MTYLSQFP A+L APL PK N A+GPG+E GN++ A F V+T NAG G + + V +P+G KE + +K+ ++ Y P + G +++ + FA I SPF V V GD KVTA GPG+EP GN G+ T+F++ T A AG G V +LD +GR+D+V+ + ++ + Y G H V+V +AG + SPF V + + + A+GRG+Q GVRV D A F+V T+ AG +L V + P R E + ++V ++E Y P GP+V+ I +G I SPF V V A K++A+GPGL G+ + A F VE G + G LGFSI+GPS+A+I C D GDGS +V Y PT PG+YAVH+LCD+E++ SP+MA I ++ P +V Sbjct: 1 DSKAIVDGNLKLILGLVWTLILHYSISMPVWE----DEEDDEAKKQTPKQRLLGWIQHKLPDLPISNFSQDWKDGRALGALVDSCAPGLCPDWEIWDVHQPIDNAREAMQQAEDWLGVAQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKNAHAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACR---ASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNVLLRNP-RGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERV 555 HSP 4 Score: 426.017 bits (1094), Expect = 4.283e-120 Identity = 504/1977 (25.49%), Postives = 809/1977 (40.92%), Query Frame = 2 Query: 1844 AFGPGL--TGGIVSKPAFFEVET-NGETGALGFSIKGPS----EAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGL-ISGISTNKPADFIVNTKNAGSPSTVKAE---CFDVTGQ--TIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPY--KVIATDR----VNTKEYPETETPL--LISADYAIDNKAYNKP----------SIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIE---GPM-----EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVD----NNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPG--LEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKP---GSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLD-------VDNHGDGTFTCQYKHDVPGNYTVKV---LYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFP-VGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPIT-GSPFKFYVDSTIPSGQVTAYGPGLSY------------GRPDMHAHFTIVTKDAGAGGLSLAVEGP--SKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF-----------TAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLY---------GDGLNDG-----MVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIE---CHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSS--------------------SLTERILRHQDAAEVSQIGNVCE-----LNLIIP-GYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHV-TGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGS-ISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXX--------XXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMIS--GSTQKGP 7345 AFGPG+ G V + A F VET N G + ++ P EA++ ++ S Y P V G + V +L ++I +SP+ + + D KVTA GPG+ SG K F + T G+ + V D G+ + + + D C Y P +PG H V V Y +P SPF VN+ EA N + G G++ + F V K AGSG++ + +L + P+ + G+G +Y P GP I + IP+SPF+V + ++ +K + T + + ++ ++ P+ +R+ + + V + PT G + V V C + SP+ ++ R + P + PL L A + K +P ++P+ K V RS ++ S ++ SN + ++ + +T K + ++ I PP + V I+ G M + D I N + T +V Y P G + + V ++++ ++DSPF + + P D +KV GPG+N TGV + FTV + GK + +P + +D +NHD +Y+ Y+P G + +TY G V SP+ V V D +IR G G LE G ++ + T G GQ L + P ++ C + G + + + ++ +PGSPF + + SKV+ +G GL G V P++F VD + AG L + V ++ G V+Y+P G + +L+ + VPGSPF V S E V V G GV L P L + + S LEL + PN + +L TFTC +K+ T + L+ K S I S+A P P L + V ++ GD + A + P G S+ + G V YVP G + V++ + +P R + R H + R +D + G + +V ++ P +G TV+Y G + + Y G IT GSPF V + +V GPGL G P M F++ AG L + +GP ++ ++ + +G ++Y P G Y + +++ + + SPF ++ G S + +D + E L+ ++ P G + +G +S+ P G + V V +P SPF + G+AS+ L G + G + E +V+ + AG G ++ + P ++E++ + DGT + + T+PG Y+I V++ +P SPF V + P + L ER L + ++ ++ +L++P + + T V PSG II D S+ F P E G+H + +K + H+ TGSP QF V + GP V G G+ G+ FTI T++AG G LS+A+EGPSKAEI QDNKDG+C V+Y PGDY ++KF +H+PGSP+M +I I DS S+ + GS + + TD + ++A + +PS ++ + + ++D+ Q + F P E G H V V +P SPFRV V SG G+ T EF VDT AG G++ V+++GPS+V+L+C++ E G Y P PG Y ++IK+ I GSPF V +SG Q +E SL Q ++ GST P Sbjct: 162 AFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPF--PVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNV-LLRNPRGEEPMRHREVGEGVHEFEYKPLALGPHVIT-ITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVR-YVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERVRHRPSAKPPLPGLPRAPQPLKTKTKKQPWPFAALYLTWALPL---KFEVVSRSTMRGNSVSDRAGSNVIIVSSSRIIIIIIIFLIDVTQSPLTVCTR-ESKCFSTKVSANAISPVVVPPGDVSVGIKCAAGAMVPVDSDVHFDIIKNDNDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPS-------HDASKVRVEGPGINATGVEAAKPAHFTVYTR---GAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPLDLGKIRVEGLGTKLEMGCEQEVRVVTRGAGGRGQ--LEARLLSPTRQKVPCSSEPLAEAAAPAAAAALLETGPHRMDVTYDGHPVPGSPFLMEAVLPANPSKVRVWGEGL--RGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLE----CHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVFGPGVEKGTTFL----PPPLHSSCSLSDSHSLLELYRSDPNQQPEHLKWKLLFVYYSPSFKMTFTCLFKYIKAVRLTPVLPTKLHKQKTTTTS--ITKASSQAPPSH-----PALRDAVSEFAVDARTISRCGGDHVRCAV-MAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAV---ADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDP------EGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQM---FSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHA--FATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQIGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLTHPAAGGRGLCERELWRAPSESIAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEM--DGP-SVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARI----------------IAGEDSLRASL-------LSRGSTHDVSLRIPDDTDPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSMEGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKF-AEEQIPGSPFTVLVSGPGRQ-----KEEVSLCQAAAPVAVVGSTCSLP 2053 HSP 5 Score: 327.02 bits (837), Expect = 7.175e-90 Identity = 313/1136 (27.55%), Postives = 486/1136 (42.78%), Query Frame = 2 Query: 929 TNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKD-SVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPF--GVMVSSKTSNSDAKQAYATGRGIQPEGVRVRD-VAEFQVHTED---AGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE-SKIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPK-SPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAEC-------FDVTGQ-----TIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERA--KTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKY------------KINNLNNTTPIGQLNE--FEILTPFDGSKVRPEIIVKSPNGSRVPVKLQE--TNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIA-----TDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAK------LTPV----------------------ERSNVKTFSNPNKQRS-NFEPNEEIIY---------------PVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPV--YQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTV 4063 N +VR +G GL G +G PA F VDT AG G L + V P + C + + S SY+P GEY + I FA++ +P SPF VK PS T+ G++ G V + T F + D L R D + +P+ K K L Y + + +F ++ +P + KT+ + +A + P +RD V+EF V G + V P + + Y Y+P GP+ V++ Y + SPF V VA + S+++ GPGL GG+ + F ++T G LG ++GP EA + ++ +G V Y PGEY HI I SP+ ++ + +P KV GPGL G+S +V AG+P +C DVT Q PV++ DG ++ YTP + G +++ V Y ++P SPF V+V+ A +A ++V G G+ + ++ T F +D + AG + I+++D D GDG F++ Y P G + + E+P SPF V + D K + P Q+ E ++ + + + V +P + V + E + F FT T GP+ + V G I NSP+ V+ R P+T T + + + PS + ++ L P +++ + N + S +F P E+ ++ P+Q + E+ P+VTAYG GL G+ A+F ID+ + L + +EGP +A+I DN DGTCSV+YLP PG Y + V + +HI SP+ I S A + + G S V+ + D ++ A I P ++ C + DG S+SP G+H + + G V SP+ V V + D R+RA G GLEE T + +F VD AG G + +S+EGP+ ++ C D +DG C V Y P +PG+Y ++IKF E+ IPGSPFTV Sbjct: 936 ANPSKVRVWGEGLR--GGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECH----DHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVK-----PSVETS---GVQVFGPGVEKGTTFLPPPLHSSCSLSDSHSLLELYRSDPNQQPEHLKW---KLLFVYYSPSFKMTFTCLFKYIKAVRLTPVLPTKLHKQKTTTTSITKASSQAPPSHPA---LRDAVSEFAVDARTISRCGGDHVRCAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEV---NPAKVRCSGPGL--GLSAG---GGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVA-VGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQIGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLTHPAAGGRGLCERELWRAPSESIAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVD--EMDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGEDSLR-----ASLLSRG-------------STHDVSLRIPDDTDPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSMEGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTV 2022 HSP 6 Score: 255.373 bits (651), Expect = 5.654e-68 Identity = 350/1472 (23.78%), Postives = 569/1472 (38.65%), Query Frame = 2 Query: 1130 YIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTK--GRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAG-FADLGVNVYGPGRSLEKCQ-IKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVD-VAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVN--IPESPFKVNVIEAGNAANIKV--YGPGIERAKTNIETYFVVDCKL---AGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIG-QLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPI-GNSPYKVIATDRVNTKEYPETETPLLISAD----YAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSNFEPNEEI------------IYPVQRTNEKAELRKPN-------VTAYGEGLVK------GVANTPAS----FIIDSTEEPPAPLGVTIEGP--MEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTG-----VFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFN-QRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIR------------AYGPGL-EEGITKQPQKFTVDLEGAG----------------QGGLGLSIEGPA--DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIP-GSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSE--AKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVG--------PVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFY 5251 Y P G + I++ F+ E+ +SPF ++V + D SKV GPGI G E + F V+T AG +D D + + +I + + ++YT ++G + V + G + SPF V V+ D + G G + E + E +V T AG L + P R C + GP+ +D+ Y +P+ SPF ++ V P SK++ +G GL GG V PA F V+T G LG +++GP EA+++C D+GDG+ +V+Y P GEYAV+IL D ++P SP+ A ++ + V +GPG+ G + P + + S E + P ++ Y Y+P T + Y P P K++ + + K P A + + F VD + G + +V+ DN DGT+ ++ + +++ ++ A +P+SPF+V + D + +++ + + N F I T G + V+ P + V + ++ GF + G + + G I SP+ V D VN + + L +SA A+ A S+ A ++ T P+ R E + + + P + A P+ + AY G V+ + PAS F ID+ E APL +TI P + +D GDG SV+YLP G Y V V Y + + SPF V + +S V + PG+ G + + VNAK G+G V + P + V+N DGT+S ++ G + I + + G + SP+ V V R R A G GL E + + P + E +G + + P+ A + DN+DGT SV + P + G +++ IK+N HIP GSP + D +D V YGPGL V + FT+D AGE L + V + + + G V+Y+P G+ I V + +PGSP++ ++ + + + G H ++ ++P D + L + P+ + DG + G + V V G ++VP SPF V V + + G L E + V+T+ AG G + GP + V E+ G V Y P + G Y + + F +E IP P Q + E S+ PV P+ + NC + R+ PR+ +G +++ G P G FK Y Sbjct: 707 YTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPSH-DASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPL---DLGKIRVEGLGTKLE---MGCEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCSSEPLAEAAAPAAAAALLETGPHRMDVTYDGHPVPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSG---VQVFGPGVEKGTTFLPPPLHSSCSLSD---SHSLLELYRSDPNQQPEHLKWKLLFVY---YSPSFKMTFTCLFKYIKAVRLTPVLPTKLHKQKTTTTSITKASSQAPPSHPALRDAVSEFAVDARTISRCGGDHVRCAVMAPSGITTEGSVTDNHDGTY-AVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGL-GLHVEGPGEAHVAFE-EDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALD----VTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQIGEPTLVLVNAKE---AGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLTHPAAGGRGLCERELWRAPSESIAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYV-DEMDGPSVTAYGPGLSHG--MVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEIS----CQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGEDSLRASLLSRGST----HDVSLRIPD-------DTDPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSMEGP--SRVELHCEDLEDGRCRVWYCPPEPGTYHLAIKFAEEQIPGSPFTVLVSGPGRQ-------------------KEEVSLCQAAAPVAVVGSTCSLPLAIPGNELFNCTAQRQLPPRVTRSGHYSVSRWLWRVGRGAAGGSDARLASPKIGETFKIY 2113 HSP 7 Score: 209.92 bits (533), Expect = 3.536e-54 Identity = 188/643 (29.24%), Postives = 294/643 (45.72%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASG-------PGIEPVGN-----EVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSK---------TSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQI---------KKVSPCLYE-------CSYIPQRPGPYVVDIKYGNNPIHL-SPFNVDVAPYKESKIKAFGPGLTGGIVSKPAFFEVET-NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNV--IEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPI 2737 ++ RVR G G+ G P FT+DT AG L I +++P G + D + +S SY+P + G Y + + + E+P SPF V+ A GD SK + PG+ G ++G T V EAG G V C +L + + V + ++ F I +T + G + + V F G I +SPF V+V + T+ A GRG+ E R +E +ED L SL K I +K SP + + S+ P G + +DIKY + I SP V + A+GPGL+ G+V K A F ++T + G L +++GPS+A+I C DN DG+ +V+Y PT PG+Y++ + ++IP SPYMA+I D L+ + G +S P D P+ + A+ +G+ ++ +DG ++PK G+H V V G ++P SPF+V V E G+A ++ G G+E A+T F+VD + AG G + +S+ E V + +D DG + Y P G + I F+E +IP SPF V + S +K +++ P+ Sbjct: 1421 DAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLD--GGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHA-FATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQIGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVD-VVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLTHPAAGGRGLC-ERELWRAPSESIAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEMDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGE---DSLRASLLSRGSTHDVSLRIPDDT--------DPALLTADIAAPSGRQDVCLLKRLDDGQIGISFSPKEVGEHLVSVREGGRHVPSSPFRVAVGASEVGDARRVRASGLGLEEARTCEAAEFIVDTRYAGFGSMCVSM--EGPSRVELHCEDLEDGRCRVWYCPPEPGTYHLA-IKFAEEQIPGSPFTV-LVSGPGRQKEEVSLCQAAAPV 2043 HSP 8 Score: 135.961 bits (341), Expect = 9.394e-32 Identity = 124/420 (29.52%), Postives = 184/420 (43.81%), Query Frame = 2 Query: 1190 PNSPF--KVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGV----NVYGPG--RSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVA-PYKESKIKAFGPGLT--GGIVSKPAFFEVET-NGETGALGFSIKGP-SEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIR----DNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEA 2398 P +P K+N KNA A GPG+E VGN V R F V T AG G V + D +G K+ + + F+ Y + G H V V FAG I SPF V+V+ + DA + A G G++P G F + T G V P R + +++ + C+Y P PGP++V + Y + SPF+V++ +A G GL G V A F V T +G L ++ P E + + G+G Y P G + + I ++IP+SP+ + + P KV A+GPGL +G++ + ADF+V + V F + G P Q R D DG+ RY P PG + V V ++ SPF +++ A Sbjct: 147 PGAPLRPKLNPKNA-------HAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPP--HGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNVLLRNPRGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEA---GPQKVRAWGPGLETGMA-GRSADFVVEAIG----TDVGTLGFSIEG---PSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPA 546 HSP 9 Score: 123.635 bits (309), Expect = 4.954e-28 Identity = 113/417 (27.10%), Postives = 182/417 (43.65%), Query Frame = 2 Query: 3191 KAELRKPNVTAYGEGLVKGVANT---PASFIIDSTEEPPAPLGVTIEGPM----EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTV-NAKPIDFNGKGIVKAIITNPFNQRSTC--TVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITK--QPQKFTVDLEGAGQGGLGLSIEGP-ADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVL---NSCEPEKV 4393 + +L N A+G G V+ V N+ A F++++ + V +E P EA++ ++ + Y P+ G + V VL+ +HI SPF V + P D KVTA GPG+ P+G + F + A G G V + +P +R T++ D C+Y P V G H + + Y G V SP+ V + + +P RA G GL+ + F V + AG G L + + P + ++ + +G +Y P G + ++I + KHIP SPF V + KV+ +GPGLE + F V+A L ++ + + G DV Y+P G+ + VL + V SPF+ ++L C PE+V Sbjct: 152 RPKLNPKNAHAFGPG-VEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPH------GDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNVLLRNPRGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETG--MAGRSADFVVEAIGTDVGTLGFSIEGPSQARIA----CDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERV 555 HSP 10 Score: 122.094 bits (305), Expect = 1.502e-27 Identity = 117/450 (26.00%), Postives = 193/450 (42.89%), Query Frame = 2 Query: 3710 PAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEE--GITKQPQKFTVDLEGAGQGGLGLSIEGPA----DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTV---PIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTV----DASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKP 5020 P VD +H + P AK P+ +P A+GPG+E ++ +F V+ E AG G + + +E P +A++ ++K + Y P+ G + V++ F +HI SPF V P H D KV GPG+E +G+ + F + D + AG + V V+D + L + + TY P G + V Y VP SPF N+ +C P +G G++ RG + + + F + T+ AG +L +++ P E + G+G +YK G + + + +G K++P SPF V V +EA P++ GP L G++ V G L GP + C + G V YVP + G Y V ++ ++E++ + ER H + + P Sbjct: 126 PNVD-EHSVMTYLSQFPKAKLKPGAPLRPKLNPKNAHAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHG--DAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQ-SRGVRVGDA--AGFRVLTKQAGSGELNVLLRNPRGEE-PMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGD--GSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERVRHRPSAKPPLP 566 HSP 11 Score: 116.701 bits (291), Expect = 6.002e-26 Identity = 105/373 (28.15%), Postives = 163/373 (43.70%), Query Frame = 2 Query: 1544 KQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQI-----KKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYK--ESKIKAFGPGL--TGGIVSKPAFFEVET-------------------NGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLIS-GISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGT 2575 K A+A G G++ G V AEF V TE+AG ++ V V P E+ ++ K+ S + Y P+ GP+ V + + I SPF V VAP K+ A GPG+ +G + K +F++ T G A+ +++ +A + C TY P VPG + V + +P SP+ I + +P A G GL S G+ A F V TK AGS + + G+ P++ R+ +G + Y P G H + +++G +IP SPF+V V ++ +GPG+E FVV+ G +G S+ E + DD GDG+ Sbjct: 158 KNAHAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRS---FVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRC----------TYRPLVPGPHIVSVGYAGAAVPHSPFSVNIG---EACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGS-GELNVLLRNPRGEE-PMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSI--EGPSQARIACDDRGDGS 510 HSP 12 Score: 109.383 bits (272), Expect = 1.061e-23 Identity = 98/373 (26.27%), Postives = 156/373 (41.82%), Query Frame = 2 Query: 1394 ITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCL-----------YECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAP---YKESKIKAFGPGLTGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVP---GEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPS---TVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKT 2452 I K + ++YT G ++ VFF+ +++ SPFG+ V + DA + G GI GV A F V+T AG A+L V E ++ P L Y Y P + G + + YG + + SPF V VAP + +++ G L G + G G L + P+ K+ C A G + + + D +P SP++ + L +P KV +G GL G PA+F V+T AG TV+ C ++ D+ DGT S Y P G++ V + + + ++P SPF V + + ++V+GPG+E+ T Sbjct: 695 IIKNDNDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDV---VPSHDASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAELDVQ-------FEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPLDLGKIRVEGLGTKLEMG-CEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCSSEPLAEAAAPAAAAALLETGPHRMDVTYDGHPVPGSPFLMEAVLPA---NPSKVRVWGEGLRGG-EVGIPAEFCVDTTAAGVGGLGLTVEGPC------EARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVFGPGVEKGTT 1046 HSP 13 Score: 101.293 bits (251), Expect = 2.734e-21 Identity = 186/831 (22.38%), Postives = 319/831 (38.39%), Query Frame = 2 Query: 5285 AYGPGLSY--GRPDMHAHFTIVTKDAGAGGLSLAVEGPS----KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPF---TAKIFGEPKKRSQICVGT--TSDVPLRISETDI-----------NNLNAIVISPTGREESC--TLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECH-DNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLI-DGGPHKVHIMGSGVER--GLANDANQFTIYTREAGA--GSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG--------HTGRINEFFVDTSNAGNGALTVTIDGP---SKVQLNCQE----NESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEF-IVDAGLAGGDVLYVGVSGPVR---PCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPF--EIVVP 7624 A+GPG+ + A F + T++AG G + + VE P +A + ++K + Y P G + + + F +HI SPF A G+ K + G + +V + + DI ++ V+ P GR ++ TL++ ++ L ++ P G H+V+V +G +P+SPF + +GE A R G V + F V T+ AG G L++ + P E H + +G YKP G ++I + + ++P SPF V + + + +++ E G + + G + S+ PS + C+ D +R++P E G + V V D V SPF + P D P +V S GL T++ +L + P K E+ + G+ V+ R G V + + + F++ + ++P + ++ K + + + IS + ++G K +A + P + + I K DN+ +V + P G + V + + SPF + V + + G + F V T AG L V + P + V + E ++ Y Y P G + + YGG+ H+ GSPF V ++ P ++ EG G K+ E+G E +V G G L + P R PC + + E G H + V + H VPGSPF E V+P Sbjct: 162 AFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNVLLRNPRGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVS---AEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACD--DRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERVRHRPSAKPPLPGLPRAPQPLKTKTKKQPWPFAALYLTWALPLKFEVVSRSTMRGN-SVSDRA---GSNVIIVSSSRIIIIIIIFLIDVTQSPLTVCTRESKCFSTKVS-ANAISPVVVPPGDVSVGIKC--------------AAGAMVPVDSDVHFDIIKNDNDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPSHDASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGD-HVPGSPFPVTVAP-----------------------------PLDLGKIRVEGLGTKL-EMGCEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCSSEPLAE--AAAPAAAAALLETGPHRMDVTYDGHPVPGSPFLMEAVLP 935 HSP 14 Score: 95.1301 bits (235), Expect = 1.964e-19 Identity = 95/324 (29.32%), Postives = 140/324 (43.21%), Query Frame = 2 Query: 932 NSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPK-GQKEP---CEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEA-GPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKE-SKIKAFGPGLTGGIVSKP 1885 ++ +VR GPG+ G PA FTV T AGK LD+ +P+ G P EI D N + +Y+ Y P +G + + + +P SPF V V D K+ G G + E+G V T A G G ++ +L +K E G H ++V + G + SPF +M + +N + + G G++ G V AEF V T AG LG+ V GP + +C C SY+P + G Y V+I + + + SPF V P E S ++ FGPG+ G P Sbjct: 740 DASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIID--NHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPL-DLGKIRVEGLGTK---LEMGCEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCS-SEPLAEAAAPAAAAALLETGPHRMDVTYDGHPVPGSPF-LMEAVLPANPSKVRVW--GEGLR--GGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTC--SVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVFGPGVEKGTTFLP 1049 HSP 15 Score: 91.6633 bits (226), Expect = 2.115e-18 Identity = 79/284 (27.82%), Postives = 113/284 (39.79%), Query Frame = 2 Query: 6818 ISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG------HTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQEN-ESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVA---------EIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 + V++PS S++ + Y+V +VP G H V V + +P SPFRV V + HG T R N F +DT AG G L + ++GP + + +E+ E G+ Y +PG+Y I YGG GSPF V + D + P V+C G GL ++ G F VD AG L V GP E V + + + Y G + L V++ DVP SPF + V Sbjct: 1162 VRCAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPV-------RDEV----------------------NPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDV 1416 HSP 16 Score: 85.5001 bits (210), Expect = 2.021e-16 Identity = 95/357 (26.61%), Postives = 151/357 (42.30%), Query Frame = 2 Query: 1754 YVVDIKYGNNPIHLSPFNVDVAPYKESKIKAFGPGL--TGGIVSKPAFFEVETNGETGALGFSIKGPSEAKIDC----VDNGDGSANVTYWPTVPGEYAVH---ILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQT-IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNV-NIPESPFKVNV------------------IEAG--------------------NAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPI 2677 Y V +++ + I SPF + V E + GL +G V+ PA F V NG G + + PS + +C +D S + VP E VH + CD ++P SP+ ++ D V+A+GPGL G +T PA+F+V+T AG S A + G + + V + +G + C Y P PG + V + YG +I SP++ V +EAG +++ ++ +GPG+ A + F VDC AGS + + VL + V G F + Y K G I + + + +P SPF+V + Sbjct: 2272 YEVSVRFEDEHIPGSPFLLTVDGVCEESRRVAVSGLLESGWKVNHPASFAVHLNGAKGRIEAKVHTPSGSVENCFVSEIDKDKWSLLAARF--VPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERG-TTGSPAEFVVDTSGAGPGSLAVA----IDGPSKVRVDCSEGPEGYHFC-YLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNAFTVDCGRAGSNVLLVGVLGPSVPCEEVHVKHAGGRRFAVTYAVKERGSYLLI-VKWGDQHVPGSPFRVTV 2619 HSP 17 Score: 80.4925 bits (197), Expect = 6.111e-15 Identity = 93/359 (25.91%), Postives = 140/359 (39.00%), Query Frame = 2 Query: 1151 EYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGR-KDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHL--SPFNVDVA-----------------------------------PYK----ESKIKAFGPGLTGGIVSKPAFFEVETNGETGA--LGFSIKGPSE--AKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQI 2089 +Y + ++F + IP SPF + V + +V SG + G +V F V A G ++ + G ++ +I K + + +E G+H V+V G + SPF V V +DA A G G+ E AEF V T AG L V + GP + C P Y Y+P PG Y+V I YG P H+ SP+ V P K SK+++ GPGL+ +V K F V+ G G+ L + GPS ++ G VTY G Y + + D+++P SP+ + Sbjct: 2271 DYEVSVRFEDEHIPGSPFLLTVDGVCEESRRVAVSG--LLESGWKVNHPASFAVHLNGA-KGRIEAKVHTPSGSVENCFVSEIDKDKWSLLAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGL--ERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCS---EGPEGYHFCYLPTAPGLYLVSICYG-GPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNAFTVDC-GRAGSNVLLVGVLGPSVPCEEVHVKHAGGRRFAVTYAVKERGSYLLIVKWGDQHVPGSPFRVTV 2619 HSP 18 Score: 75.8702 bits (185), Expect = 1.510e-13 Identity = 52/171 (30.41%), Postives = 86/171 (50.29%), Query Frame = 2 Query: 2024 EYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQT---IPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAAN---IKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISV 2518 +Y V + +DE+IP SP++ + +D + +V G L SG N PA F V+ G+ ++A+ +G +I + + R+ P+ G H V V+ ++P SPF+V V E G+AA+ + +GPG+ER T FVVD AG G + +++ Sbjct: 2271 DYEVSVRFEDEHIPGSPFL--LTVDGVCEESRRVAVSGL-LESGWKVNHPASFAVHLN--GAKGRIEAKVHTPSGSVENCFVSEIDKDKWSLLAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAI 2436 HSP 19 Score: 73.1738 bits (178), Expect = 1.095e-12 Identity = 90/346 (26.01%), Postives = 152/346 (43.93%), Query Frame = 2 Query: 2057 NIPKSPYMAQIQLDTKLFDPLKVTAYGPGLIS-GISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDG--TYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEA-GNAANIKVYGPGIERAK--TNIETYFVV----DCKLAGSGDIGISVLDEK-MRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNL---NNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVA-GFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEY----PETETPLL-ISADYAID 3034 PK+ L KL +P A+GPG+ + G S + A+F+V T+NAG V D G ++ ND ++ Y P++ G H V V + +I SPF V V G+A + GPG+E + TYF + D AG GD+ ++VLD + RD +T + + + + ++ A +P SPF V I + + + + +G F +LT GS +++++P G P++ +E G + P +GPH +T+ G I SP++V+ + ++ P ET + SAD+ ++ Sbjct: 139 QFPKAKLKPGAPLRPKL-NPKNAHAFGPGVEAVGNSVERAAEFVVETENAGL-GEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSG-ELNVLLRNPRGEE-PMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVE 480 HSP 20 Score: 70.4774 bits (171), Expect = 6.174e-12 Identity = 81/326 (24.85%), Postives = 130/326 (39.88%), Query Frame = 2 Query: 962 GLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFD-SPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNA--AGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILD--TKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGV-QIQSSPFGVMVSSK-----------------------------------TSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV 1816 GL G + +PA F V N KG ++ V P G E C + + +K + ++P G + + + + +P SPF+V V A D + V+A GPG+E G F V T+ AGPGS+ V +D +K R D + + Y GL+ V++ + G I SP+ V+ + SD+ + + G G+ V ++ F V AG L V V GP E+ +K + +Y + G Y++ +K+G+ + SPF V V Sbjct: 2306 GLLESGWKVNHPASFAVH-LNGAKGRIEAKVHTPSGSVENCFVSEIDKDKWSLLAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLE--RGTTGSPAEFVVDTSGAGPGSL-AVAIDGPSKVRVD------CSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNA--FTVDCGRAGSNVLLVGVLGPSVPCEEVHVKHAGGRRFAVTYAVKERGSYLLIVKWGDQHVPGSPFRVTV 2619 HSP 21 Score: 65.855 bits (159), Expect = 1.744e-10 Identity = 53/206 (25.73%), Postives = 95/206 (46.12%), Query Frame = 2 Query: 3137 SNFEPNEEIIYPVQRTNEKA---------ELRKPN-------VTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYND-EHIKDSPFNVTIY-PDTKSSSNIDDVAK--VTAYGPGLNPTGVFKDSFS-KFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGT 3691 + F P E ++PV T + A + +P V+A+G GL +G +PA F++D++ P L V I+GP + ++D + +G YLP PG Y+V++ Y HI SP+ + P N+ + + V A P G+ + K T ++ ++ +G G+ A++ +++ TVD G+ Sbjct: 2360 ARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEGY-HFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALV----GKQNAFTVDCGRAGS 2560 HSP 22 Score: 65.4698 bits (158), Expect = 1.995e-10 Identity = 103/432 (23.84%), Postives = 160/432 (37.04%), Query Frame = 2 Query: 6392 PHKVHIMGSGVERGLAND---ANQFTIYTREAGAGSLSIAIEGPS----KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQI-----DENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLA--SISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGH--------TGRINEFFVDTSNAGNGALTVTIDGP--SKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVS--GPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPF 7609 P H G GVE + N A +F + T AG G + + +E P +A + +++K S YR G + ++ F +H+ SPF + + D ++ V+ + + Y I D V+ P + ++ + + + P+ G H V V + +P SPF V +GE G G G F V T AG+G L V + P + + + E + F Y P A G + I+I +GG HI SPF V +S + GP K V+ G GL+ G+ +F+V+A G DV +G S GP + + G+ V Y E G + + V DV SPF Sbjct: 157 PKNAHAFGPGVE-AVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVT--------------VLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNVLLRNPRGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGK-HIPRSPFEVLVS--------------------------AEAGPQK---VRAWGPGLETGMAGRSADFVVEA--IGTDVGTLGFSIEGPSQ--ARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPF 539 HSP 23 Score: 58.9214 bits (141), Expect = 1.780e-8 Identity = 61/234 (26.07%), Postives = 90/234 (38.46%), Query Frame = 2 Query: 929 TNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFAN-SEIPNSPFKVNVKN-----------------AAGDP--------------------SKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMV 1516 ++ V A+GPGLE T G+PA F VDT AG G+L + + P + C + P Y Y+PT G Y + I + I SP++ V AG+P SKV + GPG+ VG++ F V AG + +L + V + +F + Y KE G + + V + + SPF V V Sbjct: 2397 ADAALVSAFGPGLER--GTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCS--EGPE---GYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTA--LVGKQNAFTVDCGRAGSNVLLVGVLGPSVPCEEV--HVKHAGGRRFAVTYAVKERGSYLLIVKWGDQHVPGSPFRVTV 2619 HSP 24 Score: 56.6102 bits (135), Expect = 1.082e-7 Identity = 94/384 (24.48%), Postives = 140/384 (36.46%), Query Frame = 2 Query: 6515 SKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISK--IDNNQYS--VHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG-----HTGRINEFFVDTSNAG-NGALTVTIDGPSKVQLNCQENESGYNFTYVPNAP----GDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCE-EVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 S D N + + V Y G + + F+++ V SPF ID P SK V+ E N + G A+F + G + P + + IDN+ YS V + P + G + V +PGSPF V V G+ G G E V T AG G L + P++ ++ C A G + + + Y G+ + GSPF L + V P+ P V+ G+GL+ E+G EF VD AG L + V G PCE + G+ V+Y + G + + + + + VPGSPF VV Sbjct: 689 SDVHFDIIKNDNDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPF--GIDVVPSHDASK-VRVEGPGINAT-----------GVEAAKPAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPLDLGKIRVEGLGTKLEMGCEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCSSEPLAEAAAPAAAAALLETGPHRMDVTYDGHP-VPGSPF--------------------LMEAVL---------PANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEG---PCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVV 1025
BLAST of Filamin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001908.1 (pep scaffold:Pmarinus_7.0:GL483086:279:38879:-1 gene:ENSPMAG00000001731.1 transcript:ENSPMAT00000001908.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 484.182 bits (1245), Expect = 1.822e-147 Identity = 335/956 (35.04%), Postives = 492/956 (51.46%), Query Frame = 2 Query: 716 GLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSK--------TSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVA-PYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDT---KLFDP----LKVTAYGPGLISG-ISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGN--AANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLN-NTTPIGQLNEFEILTPFDGSKVRP---EIIVKSPNGSRVPVKLQETNNGFVA-GFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPET-----ETPLLISA--DYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQRSN------FEPNEEIIYPVQRTNEKAEL-RKP------------NVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYN 3430 GLCP+W WD + + NA+EA+ A++ L V +I P E+++P VDE ++MTYL+QFP A+L APL PK N + RA+GPG+E GN + PA FTV+T +AG+G + + V +P G KE ++ +K YS Y P + G +++ + FA I SPF+V+V D SKVTA GPG+E G G+ T+F++ TA AG G V I D +GR D+V ++ + E+ F Y EG HSV V + G I SPF V V+ SN + +PE V +R V ++ ++ G D V + + E+ Q+K + P C Y+P G +VV + + I SPF V+V P E K++A+GPGL G+V PA F VE G + G LGFSI+GPS+A+I+C D GDGS +V YWP G+YAVH++CDD++I SP+MA+I ++T LF P KV +GPGL SG + KP +F V+ + AG + K D G I VQ++DN DGT+ CRYTP+ KHT + ++G V++P SP +V + AG ++V GPG++ + F VD + AG G +G++V E R+ + +DNGDGT + + + F+ +P SPF+ I D + + +G+ F + D SK + V S +G R VK + +G A FTP GPHTV++ G P+ + P KV V+T + E + A + +D +A + + +T V + P K + + + P E ++ V E + R P V +G GL G+ N P F +++ LG+ IEGP EA I DN DG+C V Y+P+ G Y V V Y Sbjct: 1 GLCPDWETWDARPPVDNAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLAQFPKAKLKPGAPLRPKLNPKKARAFGPGVEAMGNMVMKPAAFTVETISAGQGEVLVFVEDPAGHKEEAKVSPVKDKNQTYSVVYTPKVVGPHKVTVLFAGQHINKSPFEVSVAKPQADASKVTARGPGLELNGVIAGKPTYFDIHTAGAGMGDVHVTITDPRGRSDTVDVELEDRGESVFRCAYRAVLEGAHSVAVSYGGTAIPRSPFPVNVAQACRVHLCHVCSNGQRESDLQ-----KPEMVDIRPV----IYEKERG--DGSVKTFIISKGKERNQVKPLGP-TRSCEYMPSVQGKHVVSVTWAGQHIPRSPFEVEVGPPAGEQKVRAWGPGLRSGLVDHPAHFVVEAIGDDIGTLGFSIEGPSQARIECQDCGDGSCDVVYWPGEAGDYAVHVVCDDQDIKHSPFMAEI-VETGVRGLFVPNALTTKVKVFGPGLESGKVVVGKPIEFTVDAR-AGGRAPFKVYAQDAEGTPIDVQVKDNGDGTFLCRYTPRKAIKHTFLTTWGGVSVPGSPHRVQ-LXAGRHPQRGVRVSGPGLQSGEVGRPAQFSVDTRGAGDGGLGLTV--EGPREARIECEDNGDGTC-SVAYTPAEAGEHLVNVLFAGQHVPGSPFRALIHPTFDPSRVLATGRGLEKSKMGEPATFNV----DCSKAGDGDLAVDVVSDSGKRADVKTRRGPDGLHAVTFTPVTHGPHTVSLTYGGKPVPHFPAKVAVDPAVDTSGIKVSGPGVEERGVFCEAITGFTVDARALGRAGNGARV--VTRVTGPSGAMMDAPVKAKGDGTYAVEYTPCEIGVHTVDVLFEDTPVPRSPFRIAVDEGCDPSRVRVHGPGLKSGITNQPNRFTVETRGAGTGGLGLQIEGPTEAIISCTDNKDGSCLVEYVPETAGDYDVLVTYG 932 HSP 2 Score: 309.686 bits (792), Expect = 4.494e-88 Identity = 265/888 (29.84%), Postives = 404/888 (45.50%), Query Frame = 2 Query: 2402 NAANIKVYGPGIERAKTNI--ETYFVVDCKLAGSGDIGISVLD----EKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPI---ESDNDFKKYKINNLN-NTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNG---FVAGFTPTVIGPHTVTVECKGNPIGNSPY--KVIATDRV-------NTKEYPETETPLLISADYAIDNKAYN------------------KPSIPVQSAKLTP-VERSNVK--TFSNPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDV--AKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSR-IRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTP-GLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESD----LELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFN 4912 N + +GPG+E + F V+ AG G++ + V D ++ V V D N + + + F+ I +SPF+V + ++D + L N G+ F+I T G + + P G V ++ + G F + + G H+V V G I SP+ V RV N + + + P ++ I K KP P +S + P V+ +V T++ + RS FE E+ P V A+G GL G+ + PA F++++ + LG +IEGP +A+I+ D GDG+C V Y P E G Y V+V+ +D+ IK SPF I + + KV +GPGL V +FTV+A+ G+ K + V +N DGT+ C Y+P +H T+ GV V SP+ V + G P R +R GPGL+ G +P +F+VD GAG GGLGL++EGP +A+I+C DN DGTCSV Y P + G + V++ F +H+PGSPF IH D S+V G GLE+ S++ P+ F VD SKAG+ L V+V+ + S K A + + P GL VT+ P G + + Y VP P V + + + V+G GV RG + + + FT++ R G + + VTGP+ ++ V GDGT+ +Y G +TV VL+ + VP SPF + V P + + GP L + V T+ AG G L + GP I+ C+ + + G V YVP+ G Y+V + + Sbjct: 73 NPKKARAFGPGVEAMGNMVMKPAAFTVETISAGQGEVLVFVEDPAGHKEEAKVSPVKDKN---QTYSVVYTPKVVGPHKVTVLFAGQHINKSPFEVSVAKPQADASKVTARGPGLELNGVIAGKPTYFDIHTAGAGMG-DVHVTITDPRGRSDTVDVELEDRGESVFRCAYRAVLEGAHSVAVSYGGTAIPRSPFPVNVAQACRVHLCHVCSNGQRESDLQKPEMVDIRPVIYEKERGDGSVKTFIISKGKERNQVKPLGPTRSCEYMPSVQGKHVVSVTWAGQHIPRSPFE--VEVGPPAGEQK---------VRAWGPGLRSGLVDHPAHFVVEAIGDDIGTLGFSIEGPSQARIECQDCGDGSCDVVYWPGEAGDYAVHVVCDDQDIKHSPFMAEIVETGVRGLFVPNALTTKVKVFGPGLESGKVVVGKPIEFTVDAR---AGGRAPFKVYAQDAEGTPIDVQVKDNGDGTFLCRYTPRKAIKHTFLTTWGGVSVPGSPHRVQLXAGRHPQRGVRVSGPGLQSGEVGRPAQFSVDTRGAGDGGLGLTVEGPREARIECEDNGDGTCSVAYTPAEAGEHLVNVLFAGQHVPGSPFRALIHPTFDPSRVLATGRGLEK--SKMGEPATFNVDCSKAGDGDLAVDVV---SDSGKRADVKTRRGPDGLHAVTFTPVTHGPHTVSLTYGGKPVPHFPAKVAVDPAVDTSGIKVSGPGVE-ERG--VFCEAITGFTVDARALGRAGNGARVVTRVTGPSGAMMDAPVKAKGDGTYAVEYTPCEIGVHTVDVLFEDTPVPRSPFRIAVDEGCDPSRVRVHGPGLKSGITNQPNRFTVETRGAGTGGLGLQIEGPTEAIISCT--DNKDGSCLVEYVPETAGDYDVLVTYG 932 HSP 3 Score: 299.671 bits (766), Expect = 9.218e-85 Identity = 247/838 (29.47%), Postives = 371/838 (44.27%), Query Frame = 2 Query: 3068 QSAKLTPVERSNVKTFS--------NPNKQRSNFEPNEEIIYPVQRTNEKAELRKPNVTAYGEGL-VKGV-ANTPASFIIDSTEEPPAPLGVTIEGPM----EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDF---NGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDI---------VDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKV--PSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAV--VNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKF 5491 + AK++PV+ N +T+S P+K F P + + K + VTA G GL + GV A P F I + + VTI P ++ D G+ Y G++ V V Y I SPF V + + + V + G + D V+ +P+ + G G VK I + +R+ T SC Y P+V G+H + +T+ G + +SP+ V V + ++RA+GPGL G+ P F V+ G G LG SIEGP+ A+I+C D DG+C V Y P + G Y V + +++ I SPF I + +KVK +GPGLE V P +FTVDA G AP KV D + Q+ G F Y P + + VPGSP + P++ GVR L + +V P+ F+++TR AG+ L L V GP ++ +++GDGT + Y G + V VL+ ++VPGSPF +H P + G L + +G+ T V+ AGDG L+ V G G V++ P G + V L + + +P+ + A P S + + E+ VD + +G + R V V PS + GDGT V+Y P E G+H ++V + P+ SPF+ VD +V +GPGL G + FT+ T+ AG GGL L +EGP++A I C DNK+G+C V Y+P GDY + + + Sbjct: 121 EEAKVSPVKDKN-QTYSVVYTPKVVGPHKVTVLFAGQHINKSPFEVSVAKPQADASKVTARGPGLELNGVIAGKPTYFDIHTAGAGMGDVHVTITDPRGRSDTVDVELEDRGESVFRCAYRAVLEGAHSVAVSYGGTAIPRSPFPVNVAQACRVH-----LCHVCSNGQRES------DLQKPEMVDIRPVIYEKERGDGSVKTFIISKGKERNQVKPLGP---TRSCEYMPSVQGKHVVSVTWAGQHIPRSPFEVEVGPPAGEQKVRAWGPGLRSGLVDHPAHFVVEAIGDDIGTLGFSIEGPSQARIECQDCGDGSCDVVYWPGEAGDYAVHVVCDDQDIKHSPFMAEIVETGVRGLFVPNALTTKVKVFGPGLESGKVVVGKPIEFTVDARAGGRAPFKVYAQDAEGTPID-VQVKDNGD-GTFLCRYTPRKAIKHTFLTTWGGVSVPGSPHRVQLXAGRHPQR------GVRVSGPGLQSGEVGRPAQFSVDTRGAGDGGLGLTVEGPRE--ARIECEDNGDGTCSVAYTPAEAGEHLVNVLFAGQHVPGSPFRALIHPTFDPSRVLATGRGLEKSKMGEPATFNVDCSKAGDGDLAVDVVSDSGKRADVKTRRGPDGLHAVTFTPVTHGPHTVSLTYGGKPVPHFPAK-VAVDPAVDTSGIKVSGPGVEERGVFCEAITGFTVDARA-LGRAGNGARVVTRVTGPSGAMMDAPVKAKGDGTYAVEYTPCEIGVHTVDVLFEDTPVPRSPFRIAVDEGCDPSRVRVHGPGLKSGITNQPNRFTVETRGAGTGGLGLQIEGPTEAIISCTDNKDGSCLVEYVPETAGDYDVLVTY 931 HSP 4 Score: 251.521 bits (641), Expect = 6.881e-69 Identity = 233/818 (28.48%), Postives = 354/818 (43.28%), Query Frame = 2 Query: 4340 PGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGP--NNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHS-EAKPEQCYIEGP--ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKI--GAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRA-------VVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTA--------------------KIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASR-VKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGV-ERGLANDA-NQFTIYTR---EAGAGSLSIA-IEGPSKAEID--FQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDEN 6664 PG+P + LN P+K G GV G+++ P+ FT+ T AG+ ++ + V P + E + + T++ Y V G + V VL+ +++ SPF V V +A + GP LN V GK ++T AG G + P G +E E G S + + GA+ V + + IP + F + H + + + +VD + PV +++ R +++ R V L T + +Y PS G H + V + GQ I SPF+ V +V A+GPGL G D AHF + G L ++EGPS+A I+C D +G+CDV Y P GDY + + D+ I SPF A K+FG + ++ VG + + G +K +G +TP++ +H G +P SP ++ + + R V++ G GL G V QF VDTR AG GGL L++EGP + IEC DN DGTC V Y P E G +++NV +A +VPGSPF I +P+ + R+L E S++G N+ + V+S SG + D ++ F P G HTVS+ + V P + V P +D + + G GV ERG+ +A FT+ R AG G+ + + GPS A +D + DG+ V Y E G + + F D VP SPF + +DE Sbjct: 64 PGAPL-RPKLN---PKKARAFGPGVE-AMGNMVMK--PAAFTVETISAGQGEVLVFVEDPAGHKEEAKVSPVKDKNQTYSVVYTPKVVGPHKVTVLFAGQHINKSPFEVSVAKPQADASKVTARGPGLELNGVIAGKPTYFDIHTAGAGMGDVHVTITDPRGRSDTVDVELEDRGESVFRCAYRAVLEGAHSVAVSYGGTAIP-----RSPFPVNVAQACRVHLCHVCSNGQRESDLQKPEMVDIR-PV--IYEKERGDGSVKTFIISKGKERNQVKPL----GPTRSCEYMPSVQGKHVVSVTWAGQHIPRSPFEVEVGPPAGEQKVRAWGPGLRSGLVDHPAHFVVEAIGDDIGTLGFSIEGPSQARIECQDCGDGSCDVVYWPGEAGDYAVHVVCDDQDIKHSPFMAEIVETGVRGLFVPNALTTKVKVFGPGLESGKVVVGKPIEFTVDARAGGRAPFKVYAQDAEGTPIDVQVKDNGDGTFLCRYTPRKAIKHTFLTTWGGVSVPGSPHRVQLXAGR--HPQRGVRVSGPGLQSGEVGRPAQFSVDTRGAGDGGLGLTVEGPREARIECEDNGDGTCSVAYTPAEAGEHLVNVLFAGQHVPGSPFRALI--HPTFDPS-RVLATGRGLEKSKMGEPATFNVDCSKAGDGDLAVDVVSDSGKRADVKTRRGPDGLHAVTFTPVTHGPHTVSLTYGGKPVPHFPAKVAVDPAVD--TSGIKVSGPGVEERGVFCEAITGFTVDARALGRAGNGARVVTRVTGPSGAMMDAPVKAKGDGTYAVEYTPCEIGVHTVDVLFEDTPVPRSPFRIAVDEG 855 HSP 5 Score: 246.899 bits (629), Expect = 2.246e-67 Identity = 228/842 (27.08%), Postives = 364/842 (43.23%), Query Frame = 2 Query: 3710 PAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEE--GITKQPQKFTVDLEGAGQGGLGLSIEGPA----DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHD-IVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIAN-------KVPSLFTIN----TRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIR--------QYAFQPQEQYSIERTTHHYTTEQSKPIIRT--EYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDS-TIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTA---------KIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLND-GMVNETCQ-FVVDTRNAGYGG----LSLSIEGPSKVEIEC--HDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPF--AVNIGGYPS 6091 P VD +H + P AK P+ +P + RA+GPG+E + +P FTV+ AGQG + + +E PA +A++ +K+ T SV Y P+ G + V++ F +HI SPF V + D SKV GPGLE NG P+ F + + AG + V + D +S L +F Y G + V Y +P SPF NV +C R H H+ +N + P + I ++ G+ ++ + E + T +C+Y V G + V V + +++P SPF V V A ++ GP L V V G L GP + C ++ G V Y P + G Y V ++ +D++I + + F P + + E K ++ E++V P Y + P + + + +NGDGT +Y P ++ H + G + GSP + + + P V GPGL G A F++ T+ AG GGL L VEGP +A I+C DN +GTC V+Y P G++ + + F +H+ GSPF A ++ + + +G + + S+ +L V+S +G+ +R +G ++FTP G H V++ G+ +P+ P K+ V + + S +K+ G G+ + G+ E F VD R G G + + GPS ++ DGT V Y P E G + ++V + D+ VP SPF AV+ G PS Sbjct: 43 PNVD-EHSVMTYLAQFPKAKLKPGAPLRPKLNPKKARAFGPGVEAMGNMVMKPAAFTVETISAGQGEVLVFVEDPAGHKEEAKVSPVKDKNQTYSVVYTPKVVGPHKVTVLFAGQHINKSPFEVSVAKPQADASKVTARGPGLELNGVIAGKPTYFDIHTAGAGMGDVHVTITDPRGRSDTVDVELEDRGESVFRCAYRAVLEGAHSVAVSYGGTAIPRSPFPVNVAQAC------------RVHLCHVCSNGQRESDLQKPEMVDIRPVIYEKERGDGSVKTFIISKGKERNQVKPLGP---TRSCEYMPSVQGKHVVSVTWAGQHIPRSPFEVEVGPPAGEQKVRAWGPGLRSGLVDHPAHFVVEAIGDDIGTLGFSIEGPSQARIEC--QDCGDGSCDVVYWPGEAGDYAVHVVCDDQDIKHSPFMAEIVETGVRGLFVPN-ALTTKVKVFGPGLESGKVVVGKPIEFTVDARAGGRAPFKVYAQDAEGTPIDVQ----VKDNGDGTFLCRYTPRKAIKHTFLTTWGGVSVPGSPHRVQLXAGRHPQRGVRVSGPGLQSGEVGRPAQFSVDTRGAGDGGLGLTVEGPREARIECEDNGDGTCSVAYTPAEAGEHLVNVLFAGQHVPGSPFRALIHPTFDPSRVLATGRGLEKSKMGEPATFNVDCSKAGDGDLAVDVVSDSGKRADVKTRRGPDGLHAVTFTPVTHGPHTVSLTYGGKPVPHFPAKVAV--DPAVDTSGIKVSGPGVEERGVFCEAITGFTVDARALGRAGNGARVVTRVTGPSGAMMDAPVKAKGDGTYAVEYTPCEIGVHTVDVLFEDTPVPRSPFRIAVDEGCDPS 859 HSP 6 Score: 229.95 bits (585), Expect = 7.895e-62 Identity = 226/889 (25.42%), Postives = 362/889 (40.72%), Query Frame = 2 Query: 5084 VRAVVNCPSNRKDVPRL--INNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDS-TIPSGQVTAYGPGLSY-----GRPDMHAHFTIVTKDAGAGGLSLAVEGP----SKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREE------------SCTLKRLQNGYLG----ISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNI------GGYPSSSLTERILRHQDAAEVSQI--GNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPH---KVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHG--------HTGRINEFFVDT---SNAGNGALTVT-IDGPSKVQLNCQENESG---YNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNH 7588 V V P+ K+ ++ + + + T +V Y P G H++ V + GQ I SPF+ V + +VTA GPGL G+P +F I T AG G + + + P +++ D +Y + G + + + + I SPF + R +C ++ E+D+ + I P E+ S +R Q LG + P G+H+V+V +G+HIP SPF++ VG +V+ +G GL G+V+ FVV+ G L SIEGPS+ IEC D DG+C V Y P E G Y ++V D ++ SPF I G + ++LT ++ E ++ G E + + G+ ++ D F R+ P++ HT V GSP + + G H V + G G++ G QF++ TR AG G L + +EGP +A I+ +DN DG+C V Y E G+++ ++ F +HVPGSPF I + F+ SR ++ ++ +G A F ++ DG ++ V+S S K + + ++V F PV +G H V + P+P P +V V + G I F VD AGNGA VT + GPS ++ G Y Y P G +T+ + + + + SPF +A+ P V+ G GLK + N F V+ AG L + + GP ++ + V Y + G + ++V +G H Sbjct: 109 VLVFVEDPAGHKEEAKVSPVKDKNQTYSVVYTPKVVGPHKVTVLFAGQHINKSPFEVSVAKPQADASKVTARGPGLELNGVIAGKP---TYFDIHTAGAGMGDVHVTITDPRGRSDTVDVELEDRGESVFRCAYRAVLEGAHSVAVSYGGTAIPRSPFPVNV--AQACRVHLCHVCSNGQ----RESDLQKPEMVDIRPVIYEKERGDGSVKTFIISKGKERNQVKPLGPTRSCEYMPSVQGKHVVSVTWAGQHIPRSPFEVEVGPP--AGEQKVRAWGPGLRSGLVDHPAHFVVEAIGDDIGTLGFSIEGPSQARIECQDCGDGSCDVVYWPGEAGDYAVHVVCDDQDIKHSPFMAEIVETGVRGLFVPNALTTKVKVFGPGLESGKVVVGKPIEFTVDARAGGRAPFKVYAQDAEGTPIDVQVKDNGDGTFLCRYTPRKAIKHTFLTTWGGVSVPGSPHRVQ----LXAGRHPQRGVRVSGPGLQSGEVGRPAQFSVDTRGAGDGGLGLTVEGPREARIECEDNGDGTCSVAYTPAEAGEHLVNVLFAGQHVPGSPFRALI---------------HPTFDPSRVLATGRGLEKS-KMGEPATFNVDCSKAGDGDLAVDVVSDSGKRADVKTRRGPDGLHAVTFTPVTHGPHTVSLTYGGKPVPHFPAKVAVDPAVDTSGIKVSGPGVEERGVFCEAITGFTVDARALGRAGNGARVVTRVTGPSGAMMDAPVKAKGDGTYAVEYTPCEIGVHTVDVLFE-DTPVPRSPFRIAVDEG-----------------------------CDPSRVRVHGPGLKSGITNQPNRFTVETRGAGTGGLGLQIEGPTEAI--ISCTDNKDGSCLVEYVPETAGDYDVLVTYGGH 934 HSP 7 Score: 199.904 bits (507), Expect = 3.464e-52 Identity = 227/952 (23.84%), Postives = 387/952 (40.65%), Query Frame = 2 Query: 4523 NESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVP--VGKTVTIPVNTQNAGDGILSAKNVGPVGN-----IVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVP--RLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPF--------KFYVDSTIPSGQVTAYGPGLSYGRPDM-HAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKI---FGEPKKRSQ---ICVGTTSDVPLRISET---DINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGN-------ASRVKLYGDGLNDG--MVNETCQFVVDTRNAGYGGLSL---SIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNI--GGYPSSSLTERILRHQD-AAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPS--KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVIS----PSNKEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFRXXXXXXXXXXXXIHHGH------TGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFT-YVPNAPGDYTISIKYGGN 7213 E V+ +VD H T+ Q+ K PG+P + P++ GP + + V K V T +AG G + P G+ + P +N+ Y +V Y P+ +G ++V ++F ++I +PQ S + T + +I + + D G V + P R D L + G+ Y+ G H + V Y G I SPF + ++ +GQ + +P+M I K+ G G + + K Q + T Y+P G + + + + +HI SPF ++ GE K R+ + G + E DI L + P+ C + +G + + P E G++ V+V+ + I +SPF + E + ++VK++G GL G +V + +F VD R G + EG + ++++ DN DGT L Y P + + + +VPGSP V + G +P +R +R + ++G + ++ G +V P + CE D S+ + P E G H V+V +HV GSPF+ + P D P +V G G+E+ + F + +AG G L++ + S +A++ + DG VT+ G + S+ + + VP P + +D +S K +S ++++G + F ++ L A V++ PS A + + Y+V + P E G+H V VL ++P+P SPFR+ V E HG T + N F V+T AG G L + I+GP++ ++C +N+ G YVP GDY + + YGG+ Sbjct: 38 EEIVDPNVDEHSVMTYLAQFPK-------------AKLKPGAPL----RPKLNPKKARAFGPGVEAMGNMVMKPAAFTVETISAGQGEVLVFVEDPAGHKEEAKVSPVKDKNQTY---SVVYTPKVVGPHKVTVLFAGQHINKSPFEVSVAKPQADAS--KVTARGPGLELNGVIAGKPTYFDIHT-AGAGMGDVHVTITDPRGRSDTVDVELEDRGESVFRCAYRAVLEGAHSVAVSYGGTAIPRSPFPVNVAQACRVHLCHVCSNGQRES-----DLQKPEMVDIRPVIYEKERGDGSVKTFIISKGKERNQ-VKPLGPTRSCEYMPSVQGKHVVSVTWAGQHIPRSPFEVEVGPPAGEQKVRAWGPGLRSGLVDHPAHFVVEAIGDDIGTLGFSIEGPSQARIEC--QDCGDGSCDVVYWPGEAGDYAVHVVCDDQDIKHSPFMAEIVETGVRGLFVPNALTTKVKVFGPGLESGKVVVGKPIEFTVDARAGGRAPFKVYAQDAEG-TPIDVQVKDNGDGTFLCRYTPRKAIKHTFLTTWGGVSVPGSPHRVQLXAGRHP-----QRGVRVSGPGLQSGEVGRPAQFSVDTRGAGDGGLGLTVEGPREARIECE--DNGDGTCSVAYTPAEAGEHLVNVLFAGQHVPGSPFRALIHPTFD--PSRVLATGRGLEKSKMGEPATFNVDCSKAGDGDLAVDVVSDSGKRADVKTRRGPDGLHAVTFTPVTHGPHTVSLTYGGKPVPHFPAKVAVDPAVDTSGIK--------------VSGPGVEERGVFCEAITGFTVDARALGRAGNGARVVTRVTGPSGAMMDAPVKAKGDGTYAVEYTPCEIGVHTVDVLFEDTPVPRSPFRIAVDEGCDPSRVRVHGPGLKSGITNQPNRFTVETRGAGTGGLGLQIEGPTEAIISCTDNKDGSCLVEYVPETAGDYDVLVTYGGH 934 HSP 8 Score: 98.9821 bits (245), Expect = 9.090e-21 Identity = 81/283 (28.62%), Postives = 129/283 (45.58%), Query Frame = 2 Query: 941 RVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAG-PGSVDCVILDTKGRKDSV-KPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNN 1783 RV A G GLE + +G PA F VD AG G+L + V++ G++ + P+ ++ ++ P G + + + + +P+ P KV V A D S + SGPG+E G T F V G G+ V+ G ++ + + + + +EYT E G+H+V+V F + SPF + V D + G G++ G+ F V T AG LG+ + GP ++ C K CL E Y+P+ G Y V + YG + Sbjct: 664 RVLATGRGLEK--SKMGEPATFNVDCSKAGDGDLAVDVVSDSGKRADVKTRRGPDG--LHAVTFTPVTHGPHTVSLTYGGKPVPHFPAKVAVDPAV-DTSGIKVSGPGVEERGVFCEAITGFTVDARALGRAGNGARVVTRVTGPSGAMMDAPVKAKGDGTYAVEYTPCEIGVHTVDVLFEDTPVPRSPFRIAVDE---GCDPSRVRVHGPGLK-SGI-TNQPNRFTVETRGAGTGGLGLQIEGPTEAIISCTDNKDGSCLVE--YVPETAGDYDVLVTYGGH 934 HSP 9 Score: 92.4337 bits (228), Expect = 9.425e-19 Identity = 130/564 (23.05%), Postives = 211/564 (37.41%), Query Frame = 2 Query: 6212 VISPSGSFEMCEIIALSD-NQ-FSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVG-PLIDGGPHKVHIMGSGVERG--LANDANQFTIYTREAGAGSLSIAIEGP----SKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSN-KEQLASISKIDNNQYSVHFVPVENGIHNVHVLVNNSPIPGSPFR------XXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQEN--------------------------------------ESGYNFTYVPNA---------------------PGDYTISIKYGGN-------NHIIGSPFFVAISGN-------NYQSNDSIRETKSLTQTVHMISGSTQK-----GPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVV 7621 V P+G E ++ + D NQ +S+ + PK +G H V+V +H+ SPF+ +V P D KV G G+E +A F I+T AG G + + I P +++ +D + YR G + ++ + +P SPF + + + + V ++ N R + + + +I VI DGS+ ++IS + Q+ + + +Y +P G H V V IP SPF +V G G+ G F V+ G L +I+GPS+ ++ CQ+ E+G +VPNA P ++T+ + GG G+P V + N Y +I+ T T + GS + G V+ G GL+ E+G+ +F VD AG L + V GP + + G+ V Y E G HL+ V + VPGSPF ++ Sbjct: 113 VEDPAGHKEEAKVSPVKDKNQTYSVVYTPKVVGPHKVTVLFAGQHINKSPFEVSVAKPQADA--SKVTARGPGLELNGVIAGKPTYFDIHTAGAGMGDVHVTITDPRGRSDTVDVELEDRGESVFRCAYRAVLEGAHSVAVSYGGTAIPRSPFPVNV------AQACRVHLCHVCSNGQRESDLQ--KPEMVDI----RPVIYEKERGDGSVKTFIISKGKERNQVKPLGPTRSCEY----MPSVQGKHVVSVTWAGQHIPRSPFEVEVGPPAGEQKVRAWGPGLRSGLVDHPAHFVVEAIGDDIGTLGFSIEGPSQARIECQDCGDGSCDVVYWPGEAGDYAVHVVCDDQDIKHSPFMAEIVETGVRGLFVPNALTTKVKVFGPGLESGKVVVGKPIEFTVDARAGGRAPFKVYAQDAEGTPIDVQVKDNGDGTFLCRYTPRKAIKHTFLTTWGGVSVPGSPHRVQLXAGRHPQRGVRVSGPGLQSGEVGRPAQFSVDTRGAGDGGLGLTVEGPRE--ARIECEDNGDGTCSVAYTPAEAGEHLVNVLFAGQHVPGSPFRALI 656
BLAST of Filamin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004210.1 (pep scaffold:Pmarinus_7.0:GL476636:147693:235244:1 gene:ENSPMAG00000003806.1 transcript:ENSPMAT00000004210.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 506.523 bits (1303), Expect = 7.805e-146 Identity = 364/1130 (32.21%), Postives = 535/1130 (47.35%), Query Frame = 2 Query: 3554 FKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHI-PGSPFTVPIHDIVDVSKVKCYGPGLERNGS-------RVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIE-----------------GPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCS-IENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSI----------RQYAFQPQEQYSIERTTHHYTTEQ---------------SKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPI-TGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIF-GEPKKR-SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIEC---HDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSV-KSDNRHVTGSPFQFTV-GPLIDGG-----------------------------------PHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSK--AEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQI 6655 +D+ S+F V+A+ I G V+ + P + +V +NHDGTY+ Y P+ G H +++TY G V +SP+ V V G DPSR+R +GPGLE G+T + F++D AG GGLGL +EGP +A + ++ +G +V+Y PG Y I + I GSPF VP+ D V+ +KV+C GPGL + R P F+VD S+AG+A L V + +P +++ ++ G+ +TY P +G + V Y VP SPF +VL + + +V V+G GV + +P+ FTI+TR+AG++ L + + P+ V + GDG F+ Y DV G Y+V V YG VPGSPF V + +C++ GP + +G+ + VN + AG G ++ + + P + +EN G ++ + + G Y + + F + IPN R+ Q R +T Q S +R + VV F G ++ V+ PS RK PR+I+N DGT++V + P E GLHE+++ YNG I TGSP +FYVD + VTAYGPGLS+G HA FTI TKDAG GGLSLAVEGPSKAEI C DNK+GTC VSYLP APGDY I +KF +HI GSP+ A+I GE R S + G+T DV LRI E + L++G + + P E G++ V+V HIP SPF + V + + RV + G + VN F V N G + + PS C + D + P E G + ++V ++VPGSPF V +G ++ + E G+ E + G + ++ PS C + + ++P G++ VS+ H+ GSP++ V GP + GG KV G G+ L N FT+ AG+ L + + GPS E+ + VTY V E G Y+ +K+ D+HVPGSPF + + Sbjct: 1148 LRDAVSEFAVDARTISRCGGDHVRCAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTA-QGPHGTREPVEVV-QAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGV---SASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQ---IGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLWARVAQLTSTSQTCGDAGLSLAMSEDISTESLRPFHLVVPFSLRKG----HITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDE-MDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGEDSLRASLLSRGSTHDVSLRILELHCED-------------------LEDGRCRVWYCPPEPGDYEVSVRFEDEHIPGSPFLLTV-DGVCEESRRVAVSGLLESGWKVNHPASFAVHL-NGAKGRIEAKVHTPSGSVENCFVSEIDKDKWIAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDC---SEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNAFTVDCGRAGSNVLLVGVLGPSVPCEEVHVKHAGGRRFAVTYAVKERGSYLLIVKWGDQHVPGSPFRVTV 2240 HSP 2 Score: 447.973 bits (1151), Expect = 2.436e-127 Identity = 249/551 (45.19%), Postives = 343/551 (62.25%), Query Frame = 2 Query: 455 DSSDITDCRLKLILGLIWTLILHYSITMPLWEGEDANQQDGQGKGPSPKQRLLGWINSKMPHKPVKNFTTDWNDGTAIGALVDACAPGLCPNWSQWDPKQALKNAKEAINTAEEHLNVAPLIQPHEMINPKVDEKAMMTYLSQFXXXXXXXXXXXXXKTNSMRVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFT----AEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV-APYKESKIKAFGPGLTGGIVSKPAFFEVETNG-ETGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQI 2089 DS I D LKLILGL+WTLILHYSI+MP+WE +++D + K +PKQRLLGWI K+P P+ NF+ DW DG A+GALVD+CAPGLCP+W WD Q + NA+EA+ AE+ L VA +I P E+++P VDE ++MTYLSQFP A+L APL PK N A+GPG+E GN++ A F V+T NAG G + + V +P+G KE + +K+ ++ Y P + G +++ + FA I SPF V V GD KVTA GPG+EP GN G+ T+F++ T A AG G V +LD +GR+D+V+ + ++ + Y G H V+V +AG + SPF V + + + A+GRG+Q GVRV D A F+V T+ AG +L V + P R E + ++V ++E Y P GP+V+ I +G I SPF V V A K++A+GPGL G+ + A F VE G + G LGFSI+GPS+A+I C D GDGS +V Y PT PG+YAVH+LCD+E++ SP+MA I Sbjct: 1 DSKAIVDGNLKLILGLVWTLILHYSISMPVWE----DEEDDEAKKQTPKQRLLGWIQHKLPDLPISNFSQDWKDGRALGALVDSCAPGLCPDWEIWDVHQPIDNAREAMQQAEDWLGVAQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKNAHAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACR---ASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNVLLRNP-RGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHI 543 HSP 3 Score: 391.349 bits (1004), Expect = 9.199e-110 Identity = 331/1149 (28.81%), Postives = 501/1149 (43.60%), Query Frame = 2 Query: 4454 SLFTINTRD---AGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTH-HYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRA-------VVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSY-GRP-DMHAHFTIVTKDAGAGGLSLAVEGPS--KAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIF--GEPKK---------------------RSQICVGTTSDVPLRISETDINNLNAIVISPTGREESC-TLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEI-------------------ECH------------DNHDGTCLVTYKPTEPGTYIINVKYADSNVP-GSP--FAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQY-SVHFVPVENGIHNVHVLVNNSPIPGSPFR---------XXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGYNFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLT----QTVHMISGSTQ-----KGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYVQEKGRHLLMVRWGNHDVPGSPFEIVVP 7624 S F ++ R G + V P+ + V ++ DGT+ +Y G + V+V Y VP SPF V V P + + GP L + ++T+ AG G L GP V + E + G TV Y G Y + + I GS + + + R + ++ + F V D RA P ++ ++ DG + Y PS G + L V Y GQ + SPF V + +G+V G G+S G P + FTI T++AG LS+ + P + +D +G VSYLP G Y + + + + GSPF F G+ K I +G + V + E + V++P E ++ +G I FT + G +++ V G+ IPNSPF + V + + +R L Q ++ G GLSL++ E E H DN DGT V++ P E G + +++KY ++P GSP F V+ PS + L H +G + + + +V PS + C+ D S+ ++P G ++++VK +H+ GSP+ + I G + + S + RG +D SL I E+ +D +DG C V Y EPGDY S++F DEH+PGSPF+L +D + +SR ++++ L + G+ + A+F ++ +G G I A V +PS + +S+ID +++ + FVP ENG+H V V + + +PGSPFR V+ G G+ G TG EF VDTS AG G+L V IDGPSKV+++C E GY+F Y+P APG Y +SI YGG +HI GSP+ ++G ++ ET S + ++G K S V+ G GL A +GK+N F VD G AG +VL VGV GP PCEEV++KH G RF V Y V+E+G +LL+V+WG+ VPGSPF + VP Sbjct: 1153 SEFAVDARTISRCGGDHVRCAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHV--AFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSV----DCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQIGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTL----WARVAQLTSTSQTCGDAGLSLAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEMDGPSVTAYGPGLSH------GMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQ--DNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARI---IAG---EDSLRASLLSRGSTHDV-------------SLRIL-------ELHCEDLEDGRCRVWYCPPEPGDYEVSVRFEDEHIPGSPFLLTVDG---------------VCEESRRVAVSGLLESGWKVNHPASFAVHLNG-AKGRIEAKVHTPSGSVENCFVSEIDKDKWIAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNAFTVDCGRAGSNVLLVGVLGPSVPCEEVHVKHAGGRRFAVTYAVKERGSYLLIVKWGDQHVPGSPFRVTVP 2241 HSP 4 Score: 342.043 bits (876), Expect = 1.616e-94 Identity = 292/1130 (25.84%), Postives = 496/1130 (43.89%), Query Frame = 2 Query: 3299 APLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPV-AKSPYFVPVYQGSDPSRIRAYGPGLEEGITK-----------QPQKFTVDLEGAGQGGLGLSIEGPADAQ--IQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGE-------GVRPHRGHLIANKV--PSLFTINTRDAGESDLELMVTGPNNESVNLDV-DNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGIL--------SAKNVGPVGNIVPCSIE---------------------NERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIER----TTHHYTTEQSKPIIRT-EYSVVDFKFPV-GPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICVGTTSDVPLRISE-----TDIN----NLNAIVISPTGREESCTLKRL-QNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGE-NEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYAD-SNVPGSPFAVNIGG-----------------------------------YPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTV 6370 AP G+T EG + DN DGT +V Y+P G + V V Y + SPF V + ++ D ++V +GPGL G + F+++ + G G+ + P + + + +G ++ Y G++ ITY G + A SP+ VPV +P+++R GPGL G++ PQ F+VD AG L ++ +GP + ++ DG ++ Y P G Y + +++ + +P SPF V + D +V+ G G+ +G P+ FT+D +AG+APL + ++D + A++L GLF V+Y+P+ G + V Y +VPGSPF + + + K + GV G A ++ P+L +N ++AG + V P +++DV +N DGTF+ + PG Y + V +G + +P SPF V V + P P + + + +Q GD L S +++ P +VP S+ + R G +VS+ P + G +E+ + +N +IP GS Q+ + S+ +H + + I T + V GP +A ++C N+ DGT +V Y P+ G + + V + GQ I GSP+ + I +G+ + LS G T D +SL + E+ C D ++G C V Y P PGDY + ++F D+HI GSPF + G ++ ++ V + +++ +N + A V +P+G E+C + + ++ ++ F P+E G H V+V G +P SPF++ VGE +A+ V +G GL G +FVVDT AG G L+++I+GPSKV ++C + +G Y PT PG Y++++ Y ++ GSP+ + G ++S + ++ H + +G + V+ PS E + +F++ + KE G + + VK ++HV GSPF+ TV Sbjct: 1176 APSGITTEGSV------TDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAV-------ADGCDPSRVRVHGPGLE--GGLTHRANVFSIDTRAAGCGGLGL---HVEGP--GEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGL--GLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRR-ARVL-DGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQIGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRT--SPLARRTRPPTTPQTLWARVAQLTSTSQTCGDAGLSLAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEMDGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGP----SKAEISCQDNK----------DGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYM----ARIIAGEDSLRASLLSRGS----------THD-----VSLRI-----LELHCEDLEDGRCRVWYCPPEPGDYEVSVRFEDEHIPGSPFLLTVDGVCEESRRVAVSGLLESGWKVNHPASFAVHLNGAKGRIEAKVHTPSGSVENCFVSEIDKDKWIAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEGYHFC-YLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNAFTVDCGRAGSNVLLVGVLGPSVPCEEVHVKHAGGRRFAVTYAVKERGSYLLIVKWGDQHVPGSPFRVTV 2240 HSP 5 Score: 316.235 bits (809), Expect = 1.196e-86 Identity = 359/1429 (25.12%), Postives = 576/1429 (40.31%), Query Frame = 2 Query: 3395 EPGSYIVNVLYNDEHIKDSPFNV-TIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGS--------YDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDA---SKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNV-PGSPFIVPVHSEAKPEQCYIEGP---------ILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSVVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPF-----------KFYVDSTIP----SGQVTAYGPG--LSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAE--IQCIDN-KNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKR---------------------SQIC--VGTTSDVPLRISETDINNLNAI-------------VISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPN-SPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIA--LSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGL-ANDANQFTIYTREAGAGSLSIAIEGPSK-------AEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQIDENPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQ----YSVHFVPVENGIHNVHVLVNN-SPIPGSPFRXXXXXXXXXXXXIHH------------------------------------GHTGRINEFFVDTSNA--------GNGALTVTIDGPSKVQLNCQE----NESGYNF--TYVPNAPGDYTISIKYGGNNHIIGSPFFVAI 7249 E G + ++V Y+ + SPF + + P S KV +G GL G ++F V+ G G+ + P R C ++ DGT S SY P G++ ++I + V SP+ V + S ++ +GPG+E+G T P + L EG + + K P +P S VSIK + P P + + S + + P + + S+F VDA S+ G ++ V+ A + + + G + V Y+P + G +EV Y +VP SPF V + C+P +V V G G+ H ++F+I+TR AG L L V GP V + D +G FT +Y PG Y + YG + GSPF VPV E P + GP ++ V G V+ AGD L GP G P + G ++Y P +G Y + + + +++P+ + + + + + T++++ + P + + P R+++ GDG +V Y P +G + + V Y + GSPF K ++ +P G T GPG + G P + + K+AG G ++ V P + E + ++N +GT + + PG Y I ++F + I SPF + P R SQ C G + + IS + + + V P+GR+ S + ++G + +SF P E G H +++ +G HIP SP + +V E + V YG GL+ GMV + F +DT++AG GGLSL++EGPSK EI C DN DGTC V+Y PT PG Y I VK+A ++PGSP+ RI+ +D+ S + R +T V S + E+ L D + + + P E G + VSV+ ++ H+ GSPF TV + + +V + G +E G N F ++ A G + + PS +EID KD + E G + S+ + VPGSPF +++ E +++ D+ +S + GS A FV++ G GS++ + PS ++D ++ Y ++P G++ V + I GSP+R V +SG H H ++ V NA G+ L V + GPS + C+E + G F TY G Y + +K+ G+ H+ GSPF V + Sbjct: 916 ETGPHRMDVTYDGHPVPGSPFLMEAVLPANPS--------KVRVWGEGLR--GGEVGIPAEFCVDTTAAGVGGLGLT---VEGPCEARLEC--HDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVFGPGVEKGTTFLPPPLHSSCSLSDSHSLLELTEGRGETHLMYRRPKRN-------PIQPLSPCVMCLKRMSVSIK-AVRLTPVLPTKLRARPSLLSSFHQSFKPTPPSHPALRDAVSEFAVDARTISRCGGDHVRCAVM--APSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRA-----NVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDP--EGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAP----LSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQIGEPTL---VLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLWARVAQLTSTSQTCGDAGLSLAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEM---DGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEGGLSLAVEGPSKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMA------------RIIAGEDSLRASLL--------------SRGSTHDV-----SLRILELHCEDLEDGRCRVWYCPPEPGDYEVSVRFEDEHIPGSPFLLTVDGVCEES-RRVAVSGL-LESGWKVNHPASFAVHLNGA-KGRIEAKVHTPSGSVENCFVSEID----KDKWIAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAA-------------DAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSK-------VRVDCSEGPEGYHFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNAFTVDCGRAGSNVLLVGVLGPS---VPCEEVHVKHAGGRRFAVTYAVKERGSYLLIVKW-GDQHVPGSPFRVTV 2240 HSP 6 Score: 300.442 bits (768), Expect = 8.927e-82 Identity = 360/1429 (25.19%), Postives = 564/1429 (39.47%), Query Frame = 2 Query: 3668 VDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEE-GI-TKQPQKFTVDLEGAGQGGLGLSIEGP--------ADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPG--LERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIP---------------VNTQNAGDGILSAKN--VGPVGNIVPCSIENERYGHSTVS-----YVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYS--VVDFKFPVGPVFDYVRAVVNCPSNRKDVPRLINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHII-GSPFTAKIFGEPKKRSQIC-------------VGTTSDVPLRISETDINN-----LNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETC--QFVVDTRNAGYGGLSLSIEGPSKV--EIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVN---IGGYPSSSLTER--------ILRHQDAAEVSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIA-LSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIA-----------------------------IEGPS--KAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVP-GSPFMLQIDE--NPYSSYSKPVKNENIIFNDSRYISIAALQDQGFNIGSKANFVINYHGLTDGSISAYVISPSNKEQLASISKIDNNQ--YSVHFVPVENGIHNVHVLVNNSPIPGSPF--RXXXXXXXXXXXXIHHGHTGRINEFFVDTSNAGNGALTVTIDGPSKVQLNCQENESGY-NFTYVPNAPGDYTISIKYGGNNHIIGSPFFVAISGNNYQSNDSIRETKSLTQTVHMISGSTQKGPSKPYNVKCEGDGLKVAEIGKRNEFIVDAGLAGGDVLYVGVSGPVRPCEEVNIKHLGNNRFQVNYYV-QEKGRHLLMVRWGNHDVPGSPFEIVV 7621 + N++D T + Y+P G+ I + + V SP+ + V D S++R GPG+ G+ +P FTV GAG+ L + E P D++I DN D + +V+Y P + G + + + H+PGSPF V + +D+ K++ G G LE + V G L+ ++ + T+ P P + + G ++V Y+ VPGSPF+ + P KV V GEG+R G + +P+ F ++T AG L L V GP L+ +HGDGT + Y G Y V +L+ + +VPGSPF V + + GP + + G T P T+ G+ L + P+ + PC + +R S + +P K+ A L S +F+P T S P +R S VD + D+VR V PS + +N DGT V+Y PS +G H +EV Y G + SPF+ V +V +GPGL G F+I T+ AG GGL L VEGP +A + ++ G V Y +PG+Y I + I GSPF + E C VG ++ D + L+ P G E + + +G +++TP VG + ++V +G+ +P+SPF + V +A RV++ G G++ V + F +DTR AG LS++I P D DG V+Y P G Y + V Y VPGSPF V+ G L R + QIG + + + T V++P +++ +D FSI F + G + ++V+ + + SPF L+ P + L Q T ++ G LS+A + PS KA DN+DG+ V++ E G + IK+N H+P GSP +DE P + P + + +G A F I+ +G +S V PS E IS DN SV ++P G +++ V IPGSP+ R++ GE ++ + G T ++ ++L+C++ E G Y P PGDY +S+++ + HI GSPF + + G +S +SG + G ++ F V A G + V P E + + +++ +V +E G H + V VPGSPF + V Sbjct: 704 IKNDND-TLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPSHDASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEI--IDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPLDLGKIRVEGLGTKLEMGCEQEVR----VVTRGAGGRGQLEARLL-SPTRQKVPCSSEPPGHAVEHSLLFTLLETGPHRMDVTYDGHPVPGSPFLMEAVLPANPSKVRVWGEGLR---GGEVG--IPAEFCVDTTAAGVGGLGLTVEGPCE--ARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVFGPGVEK---GTTFLPPPLHSSCSLSDSHSLLELTEGRGETHLMYRRPKRNPIQPLSPCVMCLKRMSVSIKAVRLTPVLPTKLRARPSLL----------SSFHQSFKP--------------TPPSHPALRDAVSEFAVDARTISRCGGDHVRCAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAY--DAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQIGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHV----LVRTSPLARRTRPPTTPQTLWARVAQLTSTSQTCGDAGLSLAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEMDGPSVTAYGPGLSHGM-------------------VGKHAAFTIDTKDAGEGGLSLAVEGPSKAE----ISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGEDSLRASLLSRGSTHDVSLRI--------------------LELHCEDLEDGRCRVWYCPPEPGDYEVSVRF-EDEHIPGSPFLLTVDGVCEESRRV------------AVSGLLESG----------------WKVNHPASFAVHLNGAKGRI-EAKVHTPSGSVENCFVSEIDKDKWIAARFVPRENGVHPVSVTCDGASVPGSPFRVRV 2011 HSP 7 Score: 216.083 bits (549), Expect = 3.878e-56 Identity = 270/1144 (23.60%), Postives = 453/1144 (39.60%), Query Frame = 2 Query: 2777 GSKVRPEIIVKSPNGSRVPVKLQETNNG-FVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEY----PETETPLLISAD-YAIDNKAYNKPSIPVQ----SAKLTPVERSNVKTFSNPNKQRSNFEPNEEIIY-------------PVQRTNEKAELR--KPNV-TAYGEGLVKGV-ANTPASFIIDSTEEPPAPLGVTIEGPMEAK--IDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSR----IR-------------AYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQC---FDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTP-------SQFTVDASKAGEAPLKVNVI-DTATKSVKPAQIL-------------------PKSTPGLFD-------VTYIPENIGNCEIEVLYNNMQVP-GSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKPIIRTEYSV---VDFKFPVGPVFDYVRAVVNCPSNRKDVPRLIN-NGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDS---TIPSGQVTAYGPGLSYGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKAEIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMD-KHIIGSPFTAKI--------------------FGEPKKR---------------------------SQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFV 5791 G VR V +P+G + + ++G + + P+ GPH V V G + SP++V D + P E L A+ ++ID +A + + E F+ S E I Y PV+ A++R P + + G G+V V A P F +D + A L VT +GP + ++ + DG ++ Y P G Y ++V Y + + SPF V + D +V G G++ +GV + FT++ + G + I +P V + DG +S SY P V G++ + + Y V SP+ V + D S+ +R GP ++ G +P V+ + AG+G + + P ++ + DGT S+ + +PG Y ++++F + IP SPF H +V S L R TP +Q T + G+A L + + D +T+S++P ++ K++P + D V++ P G E+++ YN +P GSP Q ++ + V G G+ H + K + FTI+T+DAGE L L V GP+ ++ DN DGT + Y PG+Y++ V + +++PGSP++ + I E + ++ +T + IL E+ G V Y P + G YEV + F DE+IP +++ ++ + + V F + + A V+ PS + + + D I ++ P E+G+H + V +G + GSPF+ V + V+A+GPGL G A F + T AG G L++A++GPSK + C + G YLP APG Y + I + HI GSP+ A++ GEP++ S VG + + N L V+ P+ E +K +++ KE G +L+ V +H+P SPF++ V Sbjct: 1167 GDHVR--CAVMAPSGITTEGSVTDNHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGCDPSRVRVHGPGLEGGLTHRANVFSIDTRAAGCGGLGLHVEGPGEAHVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEVNPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVL-------AAYDAGRVRVSGAGVSASGVPASLPTDFTIDTRE---AGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPGPAIQIG---EPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPF----HVLVRTSP-------LARRTRPPTTPQTLWARVAQLTSTSQTCGDAGLSLAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPL-QFYVDEMDGPSVTAYGPGLS----HGMVGKH-AAFTIDTKDAGEGGLSLAVEGPSKAEISCQ-DNK-DGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARI--------------IAGEDSLRASLLSRGSTHDVSLRILE------------LHCEDLEDGRCRVWYCPPEPGDYEVSVRFEDEHIPGSPF---------LLTVDGVCEESRRVAVSGLLESGWKVNHPASFAVHLNGAKGRIEAKVHTPSGSVENCFVSEIDKDKWIAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEGY-HFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNAFTVDCGRAGSNVLLVGVLGPSVPCEEVHVKHAGGRRFAVTYAVKERGSYLLIVKWGDQHVPGSPFRVTV 2240 HSP 8 Score: 193.356 bits (490), Expect = 3.360e-49 Identity = 283/1164 (24.31%), Postives = 458/1164 (39.35%), Query Frame = 2 Query: 1004 FTVDTF---NAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQS-SPFGVMVSSKTSNSDAKQAYATGRGIQPEG-----VRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDV-APYKESKIKAFGPGLTGGIV--SKPAFFEVETNGETGALGFSIK------GPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLD---TKLFDPLKV---------TAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQ---IRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGS----GDIGISVL------DEKMRDVPVVTD-------------------------DNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTT--------PIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVA-GFTPTVIGPHTVTVECKGNPIGNSPY--KVIATDRVNTKEYPETETPLLISADYAIDNKAYNKPSIPVQSAKLTPVERSNVKTFSNPNKQ-----RSNFE----PNEEIIYPVQRTNEKAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVN-----------YLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGL--NPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGV-PVAKSPYF--------------------------------------VPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPA--DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPI 4069 F VD G ++ V+ P G + D N + Y+ Y+P+ G + + + +A + +P SPF+V V + DPS+V GPG+E G R F++ T AG G + L +G ++ + E F +EY G + ++ + G I + SPFGV V + N + G G+ G VR F V AG A L V GP + E ++ + ++ +Y P GPY + ++Y + SPF VDV A Y +++ G G++ V S P F ++T E G SI P A++ +D GDG +V+Y P V G Y+V + + +P SP+ +K F ++V T GPG I +P +VN K AG K C +T + + + + + DGT+S +T PG + + V +G IP SPF V V + A R T +T + +L + GD G+S+ E +R +V DN DGT ++ + P G E +I + +P S F +++ + T +G+ F I T D + + V+ P S+ + Q+ +G + + PT G +++ V+ G I SPY ++IA E L S + + + S+ + +E + + P + FE P + V E E R+ V+ E K N PASF + +G +EAK+ C V+ ++P+E G + V+V + + SPF V + + D A V+A+GPGL TG S ++F V+ G G + I P R C+ +G + C Y P G + + I Y G +A SPY +P+ SD S++ ++GPGL + + FTVD AG L + + GP+ ++ +V Y ++ GSY + +K+ ++H+PGSPF V + Sbjct: 1155 FAVDARTISRCGGDHVRCAVMAPSGITTEGSVTD--NHDGTYAVEYVPSSAGPHAVEVTYAGARVPRSPFRVAVADGC-DPSRVRVHGPGLE--GGLTHRANVFSIDTRAAGCGGLG---LHVEGPGEA-HVAFEEDPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEV-NPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVEVVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDVLAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTR-EAGDAPLSITIVDPDGFPRRARV--LDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDASKCFLAVRVPPSPLPGVTTDGGPG--PAIQIGEPTLVLVNAKEAGR---GKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRT--------RPPTTPQTLWARVAQLTSTSQTCGDAGLSLAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKG--------LHEMDIKYNGHHIPTGSPLQFYVDEMDGPSVTAYGPGLSHGMVGKHAAFTIDTK-DAGEGGLSLAVEGP--SKAEISCQDNKDGTCSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIA-----------GEDSLRAS---LLSRGSTHDVSLRILELHCEDLEDGRCRVWYCPPEPGDYEVSVRFEDEHIPGSPFLLTVDGVCE--ESRRVAVSGLLESGWK--VNHPASFAVHLN---------GAKGRIEAKVHTPSGSVENCFVSEIDKDKWIAARFVPRENGVHPVSVTCDGASVPGSPFRVRV----GEPGHAADAALVSAFGPGLERGTTG----SPAEFVVDTS---GAGPGSLAVAIDGPSKVRVDCS--EGPEGYHFC-YLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALVGKQNAFTVDCGRAGSNVLLVGVLGPSVPCEEVHVKHAGGRRFAVTYAVKERGSYLLIVKWGDQHVPGSPFRVTV 2240 HSP 9 Score: 183.341 bits (464), Expect = 3.438e-46 Identity = 244/997 (24.47%), Postives = 405/997 (40.62%), Query Frame = 2 Query: 941 RVRAYGPGLELEGNTIGNPAPFTVDTFNAGKGNLDIIVLNPKGQKEPCEIFDSPNKELAYSCSYIPTMEGEYRIIIKFANSEI-PNSPFKVNVKNAAGDPSKVTASGPGIEPVGN-------EVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGVNVYGPGRSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVAPYKESKIKAF---------GPGLT--GG-----IVSKPAFFEVETN-GETGALGFSIKGPS--EAKIDCVDN-GDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQ---LDTKLFDP------------LKVTAYGPG-------LISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIRDNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPE-SPFKVNVIEAGNAANIKVYGPGIERAKTNIETYFVVDCKLAGSGDIGISVLDEKMRDVPVVTDDNGDGTFXXXXXXXXXXXXXXXQIFFSEAEIPQSPFKVPIESDNDFKKYKINNLNNTTPIGQLNEFEILTPFDGSKVRPEIIVKSPNGSRVPVKLQETNNGFVAGFTPTVIGPHTVTVECKGNPIGNSPYKVIATDRVNTKEYPETETPLLISADYAIDNKA-----YNKPSIPVQSAKLTP---VERSNVKTFSNPNKQRSNFEPNEEIIYPVQRTNEKA---------ELRKPN-------VTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYND-EHIKDSPFNVTIY-PDTKSSSNIDDVAK--VTAYGPGLNPTGVFKDSFS-KFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGT 3691 RVR +GPGLE G F++DT AG G L + V +G E F+ + E ++ Y GEY I + + I SPF V V++ +P+KV SGPG+ G F+V + AG ++D G ++ V+ + + + + YT G +S++V +AG + SPFGV V + DA + +G G+ GV +F + T +AG A L + + P + ++ L+ SY+P G Y V + YG + + SPF V ++ K F PG+T GG + +P V G + + P E +D V+N DG+ ++ + T PG Y + + + IP SP+ ++ L + P L T+ G + IST F + + + E +G+ +I DN DGT S + P G H + + Y +IP SP + V E + ++ YGPG+ F +D K AG G G+S+ E + DN DGT T Y+I + F+ IP SP+ I + D + + + +T + IL E+ + R V + P G + V+V + I SP+ ++ D V +E L+ + + +++ A N +++ TP VE V + F P E ++PV T + A + +P V+A+G GL +G +PA F++D++ P L V I+GP + ++D + +G YLP PG Y+V++ Y HI SP+ + P N+ + + V A P G+ + K T ++ ++ +G G+ A++ +++ TVD G+ Sbjct: 1234 RVRVHGPGLE--GGLTHRANVFSIDTRAAGCGGLGLHV---EGPGEAHVAFEE-DPEGGFTVEYHAPSPGEYLFHITYGGTAITAGSPFGVPVRDEV-NPAKVRCSGPGLGLSAGGGVVGAVRAGAPQMFSVDCSRAGDAALDVTAQGPHGTREPVE--VVQAVDGIHAMTYTPSLVGPYSLHVQYAGQDVPHSPFGVDV---LAAYDAGRVRVSGAGVSASGVPASLPTDFTIDTREAGDAPLSITIVDPDGFPRRARVLDGGDGLFSVSYLPDVAGRYSVAVGYGTDEVPGSPFPVHAFATGDAS-KCFLAVRVPPSPLPGVTTDGGPGPAIQIGEPTLVLVNAKEAGRGKVTCRVLTPEQLELDVDVVENAADGTFSIVFTATQPGPYVIAVRFGGQLIPNSPFHVLVRTSPLARRTRPPTTPQTLWARVAQLTSTSQTCGDAGLSLAMSEDISTESLRPFHLVVPFSLRKGHITGEVHMPSGRKASPRIIDNRDGTMSVSFAPIEKGLHEMDIKYNGHHIPTGSPLQFYVDEM-DGPSVTAYGPGLSHGMVGKHAAFTIDTKDAGEG--GLSLAVEGPSKAEISCQDNKDGT-CSVSYLPTAPGDYSIAVKFAGQHIPGSPYMARIIAGEDSLRASLLSRGSTHDV----SLRIL----------ELHCEDLEDGRCRVW-----------YCPPEPGDYEVSVRFEDEHIPGSPF-LLTVDGV-CEESRRVAVSGLLESGWKVNHPASFAVHLNGAKGRIEAKVHTPSGSVENCFVSEIDKDKWIAARFVPRENGVHPVSVTCDGASVPGSPFRVRVGEPGHAADAALVSAFGPGLERGTTGSPAEFVVDTSGAGPGSLAVAIDGPSKVRVDCSEGPEGY-HFCYLPTAPGLYLVSICYGGPHHIAGSPYRARVTGPRLSGGHNLHETSSFLVEAGEPRRAMNGLGSEPLPLKTTSDSSKVESHGPGLSTALV----GKQNAFTVDCGRAGS 2181 HSP 10 Score: 174.481 bits (441), Expect = 1.632e-43 Identity = 107/319 (33.54%), Postives = 161/319 (50.47%), Query Frame = 2 Query: 3191 KAELRKPNVTAYGEGLVKGVANTPASFIIDSTEEPPAPLGVTIEGPMEAKI------DYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDN-NHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERN 4126 K + P + A G K PA F + + A L V E P + IDN D + +V Y P + G + V Y +H+ SPF VT+ P D+ K+ G G + T A G+G ++A + +P Q+ C+ + H +S ++ G H++D+TYDG PV SP+ + ++PS++R +G GL G P +F VD AG GGLGL++EGP +A+++C D+ DGTCSV YLP + G Y V+I F + H+PGSPFT + V+ S V+ +GPG+E+ Sbjct: 751 KVRVEGPGINATGVEAAK-----PAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPL-------DLGKIRVEGLGTKLEMGCEQEVRVVTRGA-----GGRGQLEARLLSPTRQKVPCSSEPPGHAVEHSLLFTLLETGPHRMDVTYDGHPVPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVFGPGVEKG 1052 HSP 11 Score: 159.844 bits (403), Expect = 5.027e-39 Identity = 111/341 (32.55%), Postives = 176/341 (51.61%), Query Frame = 2 Query: 5132 LINNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTIPSGQVTAYGPGLS-----YGRPDMHAHFTIVTKDAGAGGLSLAVEGPSKA------EIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKIFGEPKKRSQICV---GTTSDV----PLRISETDI---NNLNAIVISPTGREESCTLK----RLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEI-GNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNI 6076 +I N + T+TV+Y P +G + VF++ Q + SPF V + + +V GPG++ +P AHFT+ T+ AG L + E P + + IDN + + V Y P G +G+ + H+ GSPF + P +I V GT ++ +R+ L A ++SPT ++ C+ + +++ L FT E G H ++V G +P SPF + E + N S+V+++G+GL G V +F VDT AG GGL L++EGP + +ECHD+ DGTC V+Y P + G Y +N+ +AD++VPGSPF + Sbjct: 703 IIKNDNDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPSHDASKVRVEGPGINATGVEAAKP---AHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTV-APPLDLGKIRVEGLGTKLEMGCEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCSSEPPGHAVEHSLL---FTLLETGPHRMDVTYDGHPVPGSPFLM---EAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVV 1033 HSP 12 Score: 146.747 bits (369), Expect = 4.671e-35 Identity = 107/354 (30.23%), Postives = 172/354 (48.59%), Query Frame = 2 Query: 1130 YIPTMEGEYRIIIKFANSEIPNSPFKVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTK--GRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAG-FADLGVNVYGPGRSLEKCQIKKVSPCL-YECSYIPQRPGPYVVDIKYGNNPIHLSPFNVD-VAPYKESKIKAFGPGLTGGIVSKPAFFEVETNGE-TGALGFSIKGPSEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKP 2173 Y P G + I++ F+ E+ +SPF ++V + D SKV GPGI G E + F V+T AG +D D + + +I + + ++YT ++G + V + G + SPF V V+ D + G G + E + E +V T AG L + P R C + + + + GP+ +D+ Y +P+ SPF ++ V P SK++ +G GL GG V PA F V+T G LG +++GP EA+++C D+GDG+ +V+Y P GEYAV+IL D ++P SP+ A ++ + V +GPG+ G + P Sbjct: 715 YTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPSH-DASKVRVEGPGINATGVEAAKPAHFTVYTRGAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPL---DLGKIRVEGLGTKLE---MGCEQEVRVVTRGAGGRGQLEARLLSPTRQKVPCSSEPPGHAVEHSLLFTLLETGPHRMDVTYDGHPVPGSPFLMEAVLPANPSKVRVWGEGLRGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLECHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSG---VQVFGPGVEKGTTFLPP 1058 HSP 13 Score: 136.346 bits (342), Expect = 7.280e-32 Identity = 124/420 (29.52%), Postives = 184/420 (43.81%), Query Frame = 2 Query: 1190 PNSPF--KVNVKNAAGDPSKVTASGPGIEPVGNEVGRRTFFNVFTAEAGPGSVDCVILDTKGRKDSVKPKITKQSENKFLIEYTTKEEGLHSVNVFFAGVQIQSSPFGVMVSSKTSNSDAKQAYATGRGIQPEGVRVRDVAEFQVHTEDAGFADLGV----NVYGPG--RSLEKCQIKKVSPCLYECSYIPQRPGPYVVDIKYGNNPIHLSPFNVDVA-PYKESKIKAFGPGLT--GGIVSKPAFFEVET-NGETGALGFSIKGP-SEAKIDCVDNGDGSANVTYWPTVPGEYAVHILCDDENIPKSPYMAQIQLDTKLFDPLKVTAYGPGLISGISTNKPADFIVNTKNAGSPSTVKAECFDVTGQTIPVQIR----DNNDGTYSCRYTPKIPGKHTVIVSYGNVNIPESPFKVNVIEA 2398 P +P K+N KNA A GPG+E VGN V R F V T AG G V + D +G K+ + + F+ Y + G H V V FAG I SPF V+V+ + DA + A G G++P G F + T G V P R + +++ + C+Y P PGP++V + Y + SPF+V++ +A G GL G V A F V T +G L ++ P E + + G+G Y P G + + I ++IP+SP+ + + P KV A+GPGL +G++ + ADF+V + V F + G P Q R D DG+ RY P PG + V V ++ SPF +++ A Sbjct: 147 PGAPLRPKLNPKNA-------HAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPP--HGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNVLLRNPRGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEA---GPQKVRAWGPGLETGMA-GRSADFVVEAIG----TDVGTLGFSIEG---PSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPA 546 HSP 14 Score: 135.961 bits (341), Expect = 7.656e-32 Identity = 116/380 (30.53%), Postives = 175/380 (46.05%), Query Frame = 2 Query: 5597 ISETDINNLNAIVI---SPTG-REESCTLKR--LQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGL--NDGMVNETCQFVVDTRNAGYGGLSL----SIEGPS----KVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIG-----GYPSSS---LTERILRHQDAAE---VSQIGNVCELNLIIPGYNQRNTTASVISPSGSFEMCEIIALSDNQFSIRFMPKELGVHTVSVKSDNRHVTGSPFQFTVGPLIDGGPHKVHIMGSGVERGLANDANQFTIYTREAGAGSLSIAIEGPSKAEIDFQDNKDGSCGVTYRVNEPGDYVCSIKFNDEHVPGSPFMLQI 6655 + ET+ L +++ P G +EE+ R Q ++ + + P+ G H V VL +G+HI SPF + V G+A +V G G+ + + + F + T G G ++ P VE+ D TY+P PG +I++V YA + VP SPF+VNIG G +S L R +R DAA +++ ELN+++ RN P G M + + + P LG H +++ +H+ SPF+ V + GP KV G G+E G+A + F + G+L +IEGPS+A I D DGSC V Y EPGDY + ++E V SPFM I Sbjct: 181 VVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAV-YRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPH-GDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNVLL-----RN-------PRGEEPM-RHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVS--AEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHI 543 HSP 15 Score: 135.576 bits (340), Expect = 1.090e-31 Identity = 108/375 (28.80%), Postives = 165/375 (44.00%), Query Frame = 2 Query: 5084 VRAVVNCPSNRKDVPRLI--NNGDGTITVQYQPSESGLHELEVFYNGQPITGSPFKFYVDSTI-PSGQVTAYGPGL--SYGRPDMHAHFTIVTKDAGAGGLS-------LAVEGPSKA-EIQCIDNKNGTCDVSYLPLAPGDYHIGIKFMDKHIIGSPFTAKI-----------FGEPKKRSQICVGTTSDVPLRISETDINNLNAIVISPTGREESCTLKRLQNGYLGISFTPKEVGEHLVNVLRSGRHIPNSPFKIFVGENEIGNASRVKLYGDGLNDGMVNETCQFVVDTRNAGYGGLSLSIEGPSKVEIECHDNHDGTCLVTYKPTEPGTYIINVKYADSNVPGSPFAVNIGGYPSSSLTERILRHQDAAE 6136 V V P K+ R+ N+ + Y+P +G H++ V + GQ I SPF V +G+VTA GPG+ S +F I T GAG L G A E+ ++ +Y PL PG + + + + + SPF+ I G + + VG + + + LN ++ +P G EE + + G + P +G H++ + G+HIP SPF++ V +V+ +G GL GM + FVV+ G L SIEGPS+ I C D DG+C V Y PTEPG Y ++V + +V SPF +I ER+ RH+ +A+ Sbjct: 192 VLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHGDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNVLLRNPRG-EEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAE--AGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERV-RHRPSAK 562 HSP 16 Score: 128.257 bits (321), Expect = 1.811e-29 Identity = 105/370 (28.38%), Postives = 165/370 (44.59%), Query Frame = 2 Query: 3332 EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVD----NNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPG--LEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTC---SVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGV 4414 + D I N + T +V Y P G + + V ++++ ++DSPF + + P D +KV GPG+N TGV + FTV + GK + +P + +D +NHD +Y+ Y+P G + +TY G V SP+ V V D +IR G G LE G ++ + T G GQ L + P ++ C G S+ + + G + + + ++ +PGSPF + + SKV+ +G GL G V P++F VD + AG L + V ++ G V+Y+P G + +L+ + VPGSPF V S E V V G GV Sbjct: 698 DVHFDIIKNDNDTLTVKYTPPCAGRFTIMVFFSEQEVRDSPFGIDVVPS-------HDASKVRVEGPGINATGVEAAKPAHFTVYTR---GAGKAELDVQFEDPRVGAAVPILDSEIIDNHDYSYTVKYTPGQQGGVCLGVTYGGDHVPGSPFPVTVAPPLDLGKIRVEGLGTKLEMGCEQEVRVVTRGAGGRGQ--LEARLLSPTRQKVPCSSEPPGHAVEHSLLFTLLETGPHRMDVTYDGHPVPGSPFLMEAVLPANPSKVRVWGEGL--RGGEVGIPAEFCVDTTAAGVGGLGLTVEGPCEARLE----CHDHGDGTCSVSYLPVQAGEYAVNILFADAHVPGSPFTAVVKPSVETSGVQVFGPGV 1049 HSP 17 Score: 124.405 bits (311), Expect = 2.761e-28 Identity = 79/236 (33.47%), Postives = 113/236 (47.88%), Query Frame = 2 Query: 3362 DGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTVNAKPIDFNGKGIVKAIITNPFNQRSTCTVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITKQPQKFTVDLEGAGQGGLGLSIEGPADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPI 4069 D Y P PG +IV+V Y + SPF+V I + A G GL GV + F V K G G + ++ NP + + +G + Y P G H I IT+ G + +SP+ V V + P ++RA+GPGLE G+ + F V+ G G LG SIEGP+ A+I C D DG+C V+Y+P +PG Y V + +E+ + SPF I Sbjct: 319 DAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNI-------GEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQ---AGSGELNVLLRNPRGEEPMRHREVG-EGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHI 543 HSP 18 Score: 123.25 bits (308), Expect = 6.565e-28 Identity = 113/417 (27.10%), Postives = 182/417 (43.65%), Query Frame = 2 Query: 3191 KAELRKPNVTAYGEGLVKGVANT---PASFIIDSTEEPPAPLGVTIEGPM----EAKIDYIDNGDGTCSVNYLPKEPGSYIVNVLYNDEHIKDSPFNVTIYPDTKSSSNIDDVAKVTAYGPGLNPTGVFKDSFSKFTV-NAKPIDFNGKGIVKAIITNPFNQRSTC--TVDNNHDGTYSCSYSPAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEEGITK--QPQKFTVDLEGAGQGGLGLSIEGP-ADAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTVPIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTVDASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVL---NSCEPEKV 4393 + +L N A+G G V+ V N+ A F++++ + V +E P EA++ ++ + Y P+ G + V VL+ +HI SPF V + P D KVTA GPG+ P+G + F + A G G V + +P +R T++ D C+Y P V G H + + Y G V SP+ V + + +P RA G GL+ + F V + AG G L + + P + ++ + +G +Y P G + ++I + KHIP SPF V + KV+ +GPGLE + F V+A L ++ + + G DV Y+P G+ + VL + V SPF+ ++L C PE+V Sbjct: 152 RPKLNPKNAHAFGPG-VEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPH------GDAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQSRGVRVGDAAGFRVLTKQAGSGELNVLLRNPRGEEPMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETG--MAGRSADFVVEAIGTDVGTLGFSIEGPSQARIA----CDDRGDGSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERV 555 HSP 19 Score: 121.324 bits (303), Expect = 2.148e-27 Identity = 117/450 (26.00%), Postives = 193/450 (42.89%), Query Frame = 2 Query: 3710 PAVDGQHKIDITYDGVPVAKSPYFVPVYQGSDPSRIRAYGPGLEE--GITKQPQKFTVDLEGAGQGGLGLSIEGPA----DAQIQCFDNKDGTCSVQYLPQKPGSYDVSIKFNEKHIPGSPFTV---PIHDIVDVSKVKCYGPGLERNGSRVFTPSQFTV----DASKAGEAPLKVNVIDTATKSVKPAQILPKSTPGLFDVTYIPENIGNCEIEVLYNNMQVPGSPFVQNVLNSCEPEKVIVTGEGVRPHRGHLIANKVPSLFTINTRDAGESDLELMVTGPNNESVNLDVDNHGDGTFTCQYKHDVPGNYTVKVLYGNKNVPGSPFIVPVHSEAKPEQCYIEGPILNEVPVGKTVTIPVNTQNAGDGILSAKNVGPVGNIVPCSIENERYGHSTVSYVPQKIGAYEVQLMFNDENIPNGSIRQYAFQPQEQYSIERTTHHYTTEQSKP 5020 P VD +H + P AK P+ +P A+GPG+E ++ +F V+ E AG G + + +E P +A++ ++K + Y P+ G + V++ F +HI SPF V P H D KV GPG+E +G+ + F + D + AG + V V+D + L + + TY P G + V Y VP SPF N+ +C P +G G++ RG + + + F + T+ AG +L +++ P E + G+G +YK G + + + +G K++P SPF V V +EA P++ GP L G++ V G L GP + C + G V YVP + G Y V ++ ++E++ + ER H + + P Sbjct: 126 PNVD-EHSVMTYLSQFPKAKLKPGAPLRPKLNPKNAHAFGPGVEAVGNSVERAAEFVVETENAGLGEVLVFVEDPEGHKEEARVTPRNDKQRSFVAVYRPRVAGPHKVTVLFAGQHIDRSPFPVLVAPPHG--DAGKVTARGPGVEPSGNVAGKATYFDICTAGDGAGAGVGDVAVTVLDPRGRRDAVEMTLEQRRDAVLRCTYRPLVPGPHIVSVGYAGAAVPHSPFSVNIGEACNPGACRASGRGLQ-SRGVRVGDA--AGFRVLTKQAGSGELNVLLRNPRGEE-PMRHREVGEGVHEFEYKPLALGPHVITITWGGKHIPRSPFEVLVSAEAGPQKVRAWGPGLETGMAGRSADFVVEAIGTDVGTLGFSIEGPSQARIACDDRGD--GSCDVRYVPTEPGDYAVHVLCDEEDVALSPFMAHILPASRDCFPERVRHRPSAKPPLP 566 HSP 20 Score: 116.701 bits (291), Expect = 5.750e-26 Identity = 105/373 (28.15%), Postives = 16 |