SMED30023104

Overview


Name	SMED30023104
Smed ID	SMED30023104
Length (bp)	334

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SMED30023104 (SMED30023104) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30023104 (SMED30023104) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30023104 (SMED30023104) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30023104 (SMED30023104) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30023104

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
pharynx	SMED30023104	dd_Smed_v4_1576_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30023104	dd_Smed_v4_1576_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30023104	dd_Smed_v4_1576_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30023104	dd_Smed_v6_1576_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
neoblast	SMED30023104	dd_Smed_v6_1576_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of SMED30023104 vs. Ensembl Human
Match: ANK1 (ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492])

HSP 1 Score: 60.8474 bits (146), Expect = 1.639e-11
Identity = 27/64 (42.19%), Postives = 40/64 (62.50%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E ++K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  261 RGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 324

HSP 2 Score: 44.669 bits (104), Expect = 8.040e-6
Identity = 22/61 (36.07%), Postives = 37/61 (60.66%), Query Frame = 1

Query:   10 NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            NV+ E+     P+H A+R GH+++ K LL+ K ++  K K+ ++PL  A +    + VKLL
Sbjct:  434 NVKVET-----PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489

[Close]

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E ++K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  261 RGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 324

HSP 2 Score: 44.669 bits (104), Expect = 8.040e-6
Identity = 22/61 (36.07%), Postives = 37/61 (60.66%), Query Frame = 1

Query:   10 NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            NV+ E+     P+H A+R GH+++ K LL+ K ++  K K+ ++PL  A +    + VKLL
Sbjct:  434 NVKVET-----PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489

[Close]

BLAST of SMED30023104 vs. Ensembl Human
Match: ANK1 (ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492])

HSP 1 Score: 60.8474 bits (146), Expect = 1.640e-11
Identity = 27/64 (42.19%), Postives = 40/64 (62.50%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E ++K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  294 RGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 357

HSP 2 Score: 44.669 bits (104), Expect = 8.042e-6
Identity = 22/61 (36.07%), Postives = 37/61 (60.66%), Query Frame = 1

Query:   10 NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            NV+ E+     P+H A+R GH+++ K LL+ K ++  K K+ ++PL  A +    + VKLL
Sbjct:  467 NVKVET-----PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 522

[Close]

BLAST of SMED30023104 vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494])

HSP 1 Score: 55.0694 bits (131), Expect = 1.790e-9
Identity = 22/64 (34.38%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  284 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLL 347

[Close]

BLAST of SMED30023104 vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494])

HSP 1 Score: 55.0694 bits (131), Expect = 1.808e-9
Identity = 22/64 (34.38%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  273 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLL 336

[Close]

BLAST of SMED30023104 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 47.3654 bits (111), Expect = 3.691e-7
Identity = 21/64 (32.81%), Postives = 36/64 (56.25%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++ LL+ +   I  K KNG +PL +A Q +  D  + L
Sbjct:  282 RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTL 345

[Close]

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++ LL+ +   I  K KNG +PL +A Q +  D  + L
Sbjct:  282 RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTL 345

[Close]

BLAST of SMED30023104 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 47.3654 bits (111), Expect = 3.692e-7
Identity = 21/64 (32.81%), Postives = 36/64 (56.25%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++ LL+ +   I  K KNG +PL +A Q +  D  + L
Sbjct:  282 RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTL 345

[Close]

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++ LL+ +   I  K KNG +PL +A Q +  D  + L
Sbjct:  282 RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTL 345

[Close]

BLAST of SMED30023104 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 47.3654 bits (111), Expect = 3.694e-7
Identity = 21/64 (32.81%), Postives = 36/64 (56.25%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++ LL+ +   I  K KNG +PL +A Q +  D  + L
Sbjct:  282 RGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTL 345

[Close]

BLAST of SMED30023104 vs. Ensembl Fly
Match: TrpA1 (gene:FBgn0035934 transcript:FBtr0331827)

HSP 1 Score: 53.1434 bits (126), Expect = 4.570e-9
Identity = 30/76 (39.47%), Postives = 42/76 (55.26%), Query Frame = 1

Query:   43 PIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCE 270
            P+HYASR+GH   L+ L+R    I  KN N +SPL  A +  R++ V+ L + EK   II   D   +  L IS +
Sbjct:  482 PLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQ 557

[Close]

BLAST of SMED30023104 vs. Ensembl Fly
Match: TrpA1 (gene:FBgn0035934 transcript:FBtr0331826)

HSP 1 Score: 53.1434 bits (126), Expect = 4.615e-9
Identity = 30/76 (39.47%), Postives = 42/76 (55.26%), Query Frame = 1

Query:   43 PIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCE 270
            P+HYASR+GH   L+ L+R    I  KN N +SPL  A +  R++ V+ L + EK   II   D   +  L IS +
Sbjct:  447 PLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQ 522

[Close]

BLAST of SMED30023104 vs. Ensembl Fly
Match: TrpA1 (gene:FBgn0035934 transcript:FBtr0331825)

HSP 1 Score: 52.7582 bits (125), Expect = 4.845e-9
Identity = 30/76 (39.47%), Postives = 42/76 (55.26%), Query Frame = 1

Query:   43 PIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCE 270
            P+HYASR+GH   L+ L+R    I  KN N +SPL  A +  R++ V+ L + EK   II   D   +  L IS +
Sbjct:  447 PLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQ 522

[Close]

BLAST of SMED30023104 vs. Ensembl Fly
Match: TrpA1 (gene:FBgn0035934 transcript:FBtr0331824)

HSP 1 Score: 52.7582 bits (125), Expect = 4.851e-9
Identity = 30/76 (39.47%), Postives = 42/76 (55.26%), Query Frame = 1

Query:   43 PIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCE 270
            P+HYASR+GH   L+ L+R    I  KN N +SPL  A +  R++ V+ L + EK   II   D   +  L IS +
Sbjct:  482 PLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQ 557

[Close]

BLAST of SMED30023104 vs. Ensembl Fly
Match: TrpA1 (gene:FBgn0035934 transcript:FBtr0331823)

HSP 1 Score: 52.7582 bits (125), Expect = 5.143e-9
Identity = 30/76 (39.47%), Postives = 42/76 (55.26%), Query Frame = 1

Query:   43 PIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCE 270
            P+HYASR+GH   L+ L+R    I  KN N +SPL  A +  R++ V+ L + EK   II   D   +  L IS +
Sbjct:  482 PLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQ 557

[Close]

BLAST of SMED30023104 vs. Ensembl Zebrafish
Match: ank1a (ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GENE-041010-44])

HSP 1 Score: 58.9214 bits (141), Expect = 4.619e-11
Identity = 24/64 (37.50%), Postives = 41/64 (64.06%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  I+++LL +   I  K KNG SP+ +A Q +  DC++ L
Sbjct:  261 RGAKIDAKTKDELTPLHCAARNGHVRIIEILLDQGAPIQAKTKNGLSPIHMAAQGDHLDCIRQL 324

HSP 2 Score: 44.2838 bits (103), Expect = 7.334e-6
Identity = 20/64 (31.25%), Postives = 35/64 (54.69%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            +  NV C+++    P+H A++ GH+DI+ LLL+   +      NG S L +AK+      + +L
Sbjct:  723 QQANVNCKTRMSYTPLHQAAQQGHTDIVTLLLKHGAQPNEVTSNGTSALAIAKRLGYISVIDVL 786

[Close]

BLAST of SMED30023104 vs. Ensembl Zebrafish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 57.3806 bits (137), Expect = 1.570e-10
Identity = 23/64 (35.94%), Postives = 41/64 (64.06%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  ++++LL +   +  K KNG SP+ +A Q +  DCV+ L
Sbjct:  202 RGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQL 265

[Close]

BLAST of SMED30023104 vs. Ensembl Zebrafish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 57.3806 bits (137), Expect = 1.578e-10
Identity = 23/64 (35.94%), Postives = 41/64 (64.06%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  ++++LL +   +  K KNG SP+ +A Q +  DCV+ L
Sbjct:  294 RGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQL 357

[Close]

BLAST of SMED30023104 vs. Ensembl Zebrafish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 57.3806 bits (137), Expect = 1.595e-10
Identity = 23/64 (35.94%), Postives = 41/64 (64.06%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  ++++LL +   +  K KNG SP+ +A Q +  DCV+ L
Sbjct:  264 RGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQL 327

[Close]

BLAST of SMED30023104 vs. Ensembl Zebrafish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 57.3806 bits (137), Expect = 1.595e-10
Identity = 23/64 (35.94%), Postives = 41/64 (64.06%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  ++++LL +   +  K KNG SP+ +A Q +  DCV+ L
Sbjct:  272 RGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQL 335

[Close]

BLAST of SMED30023104 vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080])

HSP 1 Score: 56.9954 bits (136), Expect = 3.728e-10
Identity = 26/64 (40.62%), Postives = 38/64 (59.38%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  247 RGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 310

[Close]

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  252 RGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 315

[Close]

BLAST of SMED30023104 vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080])

HSP 1 Score: 56.9954 bits (136), Expect = 3.735e-10
Identity = 26/64 (40.62%), Postives = 38/64 (59.38%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  219 RGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 282

[Close]

BLAST of SMED30023104 vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080])

HSP 1 Score: 56.9954 bits (136), Expect = 3.736e-10
Identity = 26/64 (40.62%), Postives = 38/64 (59.38%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  257 RGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 320

[Close]

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  294 RGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 357

[Close]

BLAST of SMED30023104 vs. Ensembl Mouse
Match: Ank1 (ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88024])

HSP 1 Score: 60.4622 bits (145), Expect = 1.414e-11
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  265 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 328

[Close]

BLAST of SMED30023104 vs. Ensembl Mouse
Match: Ank1 (ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88024])

HSP 1 Score: 60.4622 bits (145), Expect = 1.485e-11
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  265 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 328

[Close]

BLAST of SMED30023104 vs. Ensembl Mouse
Match: Ank1 (ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88024])

HSP 1 Score: 60.4622 bits (145), Expect = 1.517e-11
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  294 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 357

[Close]

BLAST of SMED30023104 vs. Ensembl Mouse
Match: Ank1 (ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88024])

HSP 1 Score: 60.4622 bits (145), Expect = 1.520e-11
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  265 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 328

[Close]

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  265 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 328

[Close]

BLAST of SMED30023104 vs. UniProt/SwissProt
Match: sp|P16157|ANK1_HUMAN (Ankyrin-1 OS=Homo sapiens OX=9606 GN=ANK1 PE=1 SV=3)

HSP 1 Score: 60.8474 bits (146), Expect = 7.871e-11
Identity = 27/64 (42.19%), Postives = 40/64 (62.50%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E ++K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  261 RGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 324

[Close]

BLAST of SMED30023104 vs. UniProt/SwissProt
Match: sp|Q02357|ANK1_MOUSE (Ankyrin-1 OS=Mus musculus OX=10090 GN=Ank1 PE=1 SV=2)

HSP 1 Score: 60.4622 bits (145), Expect = 1.064e-10
Identity = 27/64 (42.19%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  257 RGAQIETRTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 320

[Close]

BLAST of SMED30023104 vs. UniProt/SwissProt
Match: sp|G5E8K5|ANK3_MOUSE (Ankyrin-3 OS=Mus musculus OX=10090 GN=Ank3 PE=1 SV=1)

HSP 1 Score: 55.4546 bits (132), Expect = 7.158e-9
Identity = 22/64 (34.38%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  273 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLL 336

[Close]

BLAST of SMED30023104 vs. UniProt/SwissProt
Match: sp|Q8C8R3|ANK2_MOUSE (Ankyrin-2 OS=Mus musculus OX=10090 GN=Ank2 PE=1 SV=2)

HSP 1 Score: 55.0694 bits (131), Expect = 7.926e-9
Identity = 23/64 (35.94%), Postives = 40/64 (62.50%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H A+R+GH  +++LLL  K  +  + KNG SPL +A Q +  +CVK L
Sbjct:  288 RGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHL 351

[Close]

BLAST of SMED30023104 vs. UniProt/SwissProt
Match: sp|O70511|ANK3_RAT (Ankyrin-3 OS=Rattus norvegicus OX=10116 GN=Ank3 PE=1 SV=3)

HSP 1 Score: 55.0694 bits (131), Expect = 8.673e-9
Identity = 22/64 (34.38%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  298 RGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLL 361

[Close]

BLAST of SMED30023104 vs. TrEMBL
Match: A0A059LBQ3 (ANK_REP_REGION domain-containing protein (Fragment) OS=Helicosporidium sp. ATCC 50920 OX=1291522 GN=H632_c4503p0 PE=4 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 4.385e-10
Identity = 25/66 (37.88%), Postives = 39/66 (59.09%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTN 198
            R     C+ KSK+ P HYA+ +GH ++L+LL  +   +  ++  G+SPL LA    + DCV+ L N
Sbjct:    7 RGAETSCQDKSKLTPAHYAAAHGHEEVLRLLWSKGTDLDAESPGGQSPLHLAAAAGQADCVRFLVN 72

[Close]

BLAST of SMED30023104 vs. TrEMBL
Match: A0A1A8HDW4 (Ankyrin 1, erythrocytic (Fragment) OS=Nothobranchius korthausae OX=1143690 GN=ANK1 PE=4 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 4.268e-9
Identity = 25/64 (39.06%), Postives = 40/64 (62.50%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  I+++LL     I  K KNG SP+ +A Q +  DCV+ L
Sbjct:   95 RGAQIDAKTKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQL 158

[Close]

BLAST of SMED30023104 vs. TrEMBL
Match: V8NF47 (Ankyrin-1 OS=Ophiophagus hannah OX=8665 GN=ANK1 PE=4 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 4.450e-9
Identity = 28/64 (43.75%), Postives = 40/64 (62.50%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R  N+E  +K ++ P+H A+RNGH  I ++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  218 RGANIEVRTKDELTPLHCAARNGHLRIAEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLL 281

[Close]

BLAST of SMED30023104 vs. TrEMBL
Match: A0A4Z2J7F7 (Ankyrin-1 OS=Liparis tanakae OX=230148 GN=Ank1_0 PE=4 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 5.113e-9
Identity = 26/64 (40.62%), Postives = 40/64 (62.50%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A+RNGH+ I+++LL     I  K KNG SP+ +A Q +  DCVK L
Sbjct:  212 RGAQIDAVTKDELTPLHCAARNGHARIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVKQL 275

[Close]

BLAST of SMED30023104 vs. TrEMBL
Match: M7B3Q0 (Ankyrin-1 OS=Chelonia mydas OX=8469 GN=UY3_11160 PE=4 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 6.658e-9
Identity = 27/64 (42.19%), Postives = 40/64 (62.50%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E  +K ++ P+H A+RNGH  I+++LL     I  K KNG SP+ +A Q +  DCV+LL
Sbjct:  197 RGAQIETRTKDELTPLHCAARNGHMRIMEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLL 260

[Close]

BLAST of SMED30023104 vs. Ensembl Cavefish
Match: ank1a (ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GENE-041010-44])

HSP 1 Score: 59.3066 bits (142), Expect = 2.831e-11
Identity = 25/64 (39.06%), Postives = 41/64 (64.06%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  I+++LL +   I  K KNG SP+ +A Q +  DCV+ L
Sbjct:  233 RGATIDAKTKDELTPLHCAARNGHVRIIEILLDQGAPIQAKTKNGLSPIHMAAQGDHMDCVRQL 296

[Close]

BLAST of SMED30023104 vs. Ensembl Cavefish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 58.5362 bits (140), Expect = 6.097e-11
Identity = 24/64 (37.50%), Postives = 40/64 (62.50%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K ++ P+H A+RNGH  ++++LL +   I  K KNG SP+ +A Q +  DCV+ L
Sbjct:  236 RGAQIDARTKDELTPLHCAARNGHVRVIEILLDQGAPIQAKTKNGLSPIHMAAQGDHMDCVRQL 299

HSP 2 Score: 43.8986 bits (102), Expect = 7.026e-6
Identity = 23/68 (33.82%), Postives = 39/68 (57.35%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQ---CNRFDCVKLLT 195
            +  +V C+++    P+H A++ GH+DI+ LLL+          NG SPL +AK+    +  D +KL+T
Sbjct:  703 QQAHVNCKTRVGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIAKRLGYISVIDVLKLVT 770

[Close]

BLAST of SMED30023104 vs. Ensembl Cavefish
Match: ank3b (ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2])

HSP 1 Score: 56.6102 bits (135), Expect = 2.749e-10
Identity = 24/68 (35.29%), Postives = 41/68 (60.29%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNME 204
            R   ++ ++K  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL + E
Sbjct:  237 RGARIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLHHE 304

[Close]

BLAST of SMED30023104 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1])

HSP 1 Score: 55.8398 bits (133), Expect = 5.587e-10
Identity = 23/64 (35.94%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  292 RGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLL 355

HSP 2 Score: 44.2838 bits (103), Expect = 5.840e-6
Identity = 20/58 (34.48%), Postives = 34/58 (58.62%), Query Frame = 1

Query:   25 SKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTN 198
            ++  + P+H A++ G  D++ LLL +   +   NKNG +PL LA Q +R    ++L N
Sbjct:  663 TRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLN 720

[Close]

BLAST of SMED30023104 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1])

HSP 1 Score: 55.8398 bits (133), Expect = 5.600e-10
Identity = 23/64 (35.94%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  264 RGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLL 327

HSP 2 Score: 44.2838 bits (103), Expect = 5.854e-6
Identity = 20/58 (34.48%), Postives = 34/58 (58.62%), Query Frame = 1

Query:   25 SKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTN 198
            ++  + P+H A++ G  D++ LLL +   +   NKNG +PL LA Q +R    ++L N
Sbjct:  635 TRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLN 692

[Close]

BLAST of SMED30023104 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 1.301e-10
Identity = 23/64 (35.94%), Postives = 38/64 (59.38%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H A+R+GH  ++++LL     I  K KNG SPL +A Q     CV+LL
Sbjct:  260 RGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLL 323

HSP 2 Score: 43.5134 bits (101), Expect = 1.929e-6
Identity = 24/92 (26.09%), Postives = 45/92 (48.91%), Query Frame = 1

Query:   10 NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDD--PIEIEKLFISCEFIR 279
            ++   ++S + PIH AS  GH ++++LLL+        N  G++PL +A +  + + VK L        +  R+D  P+ I       E ++
Sbjct:  395 SIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQ 486

[Close]

BLAST of SMED30023104 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 1.307e-10
Identity = 23/64 (35.94%), Postives = 38/64 (59.38%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H A+R+GH  ++++LL     I  K KNG SPL +A Q     CV+LL
Sbjct:  267 RGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLL 330

HSP 2 Score: 43.5134 bits (101), Expect = 1.938e-6
Identity = 24/92 (26.09%), Postives = 45/92 (48.91%), Query Frame = 1

Query:   10 NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDD--PIEIEKLFISCEFIR 279
            ++   ++S + PIH AS  GH ++++LLL+        N  G++PL +A +  + + VK L        +  R+D  P+ I       E ++
Sbjct:  402 SIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQ 493

[Close]

BLAST of SMED30023104 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.6026 bits (122), Expect = 3.141e-9
Identity = 21/52 (40.38%), Postives = 35/52 (67.31%), Query Frame = 1

Query:   37 MRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            + P+H A+R+GH  ++++LL +   I  K KNG SPL +A Q +  +CV++L
Sbjct:    7 LTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVL 58

[Close]

BLAST of SMED30023104 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003991.1 (pep scaffold:Pmarinus_7.0:GL484476:255315:281660:1 gene:ENSPMAG00000003623.1 transcript:ENSPMAT00000003991.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 1.211e-8
Identity = 25/79 (31.65%), Postives = 42/79 (53.16%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDP 237
            +  N+    K   R IH+A+  GH++++K+L+     + CK+K G SPL  A    +   VKLL ++      ++ DDP
Sbjct:  160 KGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAHGADVRCKDKKGYSPLHAASSSGQIGVVKLLLDLG-----VDIDDP 233

[Close]

BLAST of SMED30023104 vs. Ensembl Sea Lamprey
Match: asap2a (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a [Source:ZFIN;Acc:ZDB-GENE-041210-256])

HSP 1 Score: 47.7506 bits (112), Expect = 7.292e-8
Identity = 27/69 (39.13%), Postives = 42/69 (60.87%), Query Frame = 1

Query:    4 NC-NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEK 207
            NC NV  ++++    +H+ SR   ++ LKLLLR K  ++  N+ G++ LD+AKQ +   C  LLT  EK
Sbjct:  546 NCRNVNKQTENGNTALHFCSRYNATECLKLLLRSKAALHVSNEAGETALDIAKQMDHAQCEDLLTLAEK 614

[Close]

BLAST of SMED30023104 vs. Ensembl Yeast
Match: PHO81 (Cyclin-dependent kinase (CDK) inhibitor; regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003465])

HSP 1 Score: 44.669 bits (104), Expect = 5.902e-7
Identity = 21/59 (35.59%), Postives = 33/59 (55.93%), Query Frame = 1

Query:   16 ECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            E +  +K  PI YA R+GHS+++  LL+   R+  ++ NG SPL  A   +  D +  L
Sbjct:  586 EIDGFNKWTPIFYAVRSGHSEVITELLKHNARLDIEDDNGHSPLFYALWESHVDVLNAL 644

[Close]

BLAST of SMED30023104 vs. Ensembl Nematostella
Match: EDO38657 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCC3])

HSP 1 Score: 45.8246 bits (107), Expect = 9.542e-8
Identity = 22/61 (36.07%), Postives = 34/61 (55.74%), Query Frame = 1

Query:   10 NVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            N++ +S S +  +HYA+  G  + L+LL+ +  RI   +  G SPLD A +   FDC   L
Sbjct:   20 NIDHQSASGLTALHYAALEGSFECLELLVNKGARIDILDSKGCSPLDFAVRGGNFDCAAYL 80

[Close]

BLAST of SMED30023104 vs. Ensembl Nematostella
Match: EDO45485 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSW0])

HSP 1 Score: 43.1282 bits (100), Expect = 4.904e-7
Identity = 20/50 (40.00%), Postives = 28/50 (56.00%), Query Frame = 1

Query:   43 PIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            P+H A   GH +I+KLLL E   +  + KNG  PL LA Q      +++L
Sbjct:    4 PLHIAVVYGHWEIVKLLLDEGADVEAQTKNGYQPLHLAAQYGHKIIIEIL 53

[Close]

BLAST of SMED30023104 vs. Ensembl Nematostella
Match: EDO49727 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFI4])

HSP 1 Score: 43.8986 bits (102), Expect = 6.510e-7
Identity = 17/51 (33.33%), Postives = 30/51 (58.82%), Query Frame = 1

Query:    4 NCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLA 156
              +V+   +    P+H+A+  G+ DI++LLLR    +   N++G  P+DLA
Sbjct:   45 GADVDKTDRYGWAPLHHAAAEGYIDIVRLLLRANANVRALNQHGHMPMDLA 95

[Close]

BLAST of SMED30023104 vs. Ensembl Nematostella
Match: EDO28510 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T695])

HSP 1 Score: 45.0542 bits (105), Expect = 1.082e-6
Identity = 18/52 (34.62%), Postives = 34/52 (65.38%), Query Frame = 1

Query:   43 PIHYASRNGHSDILKLLLREKC--RIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            P+H+A + G +++ K+LLR      I+ +N NGK+P+ LAK+    + ++L+
Sbjct:  132 PLHFAGQAGKTEVAKVLLRSGAAESIHIENSNGKTPVQLAKESGHSETLELV 183

[Close]

BLAST of SMED30023104 vs. Ensembl Nematostella
Match: EDO26963 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAK8])

HSP 1 Score: 40.817 bits (94), Expect = 4.632e-6
Identity = 19/46 (41.30%), Postives = 28/46 (60.87%), Query Frame = 1

Query:   55 ASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            A+RNG S+ L+LL R+   +  +NK+GK PL  A      +CV+ L
Sbjct:    9 AARNGRSETLELLYRKGVDLEKRNKDGKRPLHEAASAGSLECVQFL 54

[Close]

BLAST of SMED30023104 vs. Ensembl Medaka
Match: ank1b (ankyrin-1 [Source:NCBI gene;Acc:101157380])

HSP 1 Score: 59.6918 bits (143), Expect = 2.250e-11
Identity = 25/64 (39.06%), Postives = 40/64 (62.50%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ ++K ++ P+H A+RNGH  I+++LL     I  K KNG SP+ +A Q +  DCV+ L
Sbjct:  259 RGAQIDAQTKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQL 322

[Close]

BLAST of SMED30023104 vs. Ensembl Medaka
Match: ENSORLT00000040233.1 (pep primary_assembly:ASM223467v1:19:16412534:16434057:1 gene:ENSORLG00000021910.1 transcript:ENSORLT00000040233.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.9954 bits (136), Expect = 2.070e-10
Identity = 24/64 (37.50%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++  +K  + P+H A+R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  266 RGSKIDARTKDGLTPLHCAARSGHEQVVEMLLNRGAPILSKTKNGLSPLHMATQGDHLNCVQLL 329

HSP 2 Score: 44.669 bits (104), Expect = 4.201e-6
Identity = 20/66 (30.30%), Postives = 40/66 (60.61%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTN 198
            R   V+ ++++ + P+H AS+ G+S++++LLL    +I  + K+G +PL  A +      V++L N
Sbjct:  233 RGAAVDFKARNDITPLHVASKRGNSNMVRLLLERGSKIDARTKDGLTPLHCAARSGHEQVVEMLLN 298

[Close]

BLAST of SMED30023104 vs. Ensembl Medaka
Match: ENSORLT00000039903.1 (pep primary_assembly:ASM223467v1:15:18469388:18484014:-1 gene:ENSORLG00000030042.1 transcript:ENSORLT00000039903.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.6102 bits (135), Expect = 2.575e-10
Identity = 24/64 (37.50%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   +E ++K  + P+H  +R+GH  ++++LL     I  K KNG SPL +A Q +  +CV+LL
Sbjct:  266 RGARIEAKTKDGLTPLHCGARSGHEQVVEILLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLL 329

[Close]

BLAST of SMED30023104 vs. Ensembl Medaka
Match: ENSORLT00000006308.2 (pep primary_assembly:ASM223467v1:1:12516834:12530692:1 gene:ENSORLG00000005003.2 transcript:ENSORLT00000006308.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.6842 bits (130), Expect = 1.029e-9
Identity = 23/64 (35.94%), Postives = 39/64 (60.94%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            R   ++ +++  + P+H A+R+GH   ++LLL     I  + KNG SPL ++ Q +  +CVKLL
Sbjct:  236 RGAQIDAKTRDGLTPLHCAARSGHDPAVELLLERGAPILARTKNGLSPLHMSAQGDHIECVKLL 299

[Close]

BLAST of SMED30023104 vs. Ensembl Medaka
Match: ank1a (ankyrin-1 [Source:NCBI gene;Acc:101174837])

HSP 1 Score: 53.5286 bits (127), Expect = 3.767e-9
Identity = 24/56 (42.86%), Postives = 35/56 (62.50%), Query Frame = 1

Query:   25 SKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            +  ++ P+H A+RNGH  I+++LL     I  K KNG SP+ +A Q +  DCVK L
Sbjct:  207 ANDELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQL 262

HSP 2 Score: 46.9802 bits (110), Expect = 6.799e-7
Identity = 23/64 (35.94%), Postives = 35/64 (54.69%), Query Frame = 1

Query:   13 VECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNME 204
            V+ ++K    P+H A+R GH +++KLLL  K         G SPL +A +      V+LL +ME
Sbjct:  401 VDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDME 464

[Close]

BLAST of SMED30023104 vs. Planmine SMEST
Match: SMESG000019970.1 (SMESG000019970.1)

HSP 1 Score: 194.897 bits (494), Expect = 3.304e-59
Identity = 95/111 (85.59%), Postives = 100/111 (90.09%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCEFIRENICTGLNVLEMAMTSNA 333
            RNCN ECESKSK RPIHYASR GHS+I+KL L+ K RI CKNK+GKSPLD+AKQ NR DCVKLLTNMEKLFAIIERD PIEIEKLFISCEFIRENI TGLNVLEMAMTSNA
Sbjct:   59 RNCNTECESKSKWRPIHYASREGHSEIVKLFLQRKWRIDCKNKDGKSPLDIAKQFNRVDCVKLLTNMEKLFAIIERDAPIEIEKLFISCEFIRENIYTGLNVLEMAMTSNA 169

[Close]

BLAST of SMED30023104 vs. Planmine SMEST
Match: SMESG000010347.1 (SMESG000010347.1)

HSP 1 Score: 188.348 bits (477), Expect = 4.759e-59
Identity = 93/111 (83.78%), Postives = 100/111 (90.09%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCEFIRENICTGLNVLEMAMTSNA 333
            RNCN+ECE KSK RPIH AS NGHS+ LKLLL+ KCRI  KNK+GKSPLD+AKQ NR DCV+LLT+MEKLFAIIERDDPIEIEKLFISCEFIRENI TGLNVLEMAMTSNA
Sbjct:   92 RNCNIECEDKSKWRPIHCASWNGHSETLKLLLQWKCRIDYKNKDGKSPLDIAKQYNRVDCVELLTHMEKLFAIIERDDPIEIEKLFISCEFIRENIYTGLNVLEMAMTSNA 202

[Close]

BLAST of SMED30023104 vs. Planmine SMEST
Match: SMESG000019959.1 (SMESG000019959.1)

HSP 1 Score: 190.66 bits (483), Expect = 1.720e-57
Identity = 92/111 (82.88%), Postives = 100/111 (90.09%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCEFIRENICTGLNVLEMAMTSNA 333
            RNCN ECE++S  RPIHYASR GHS+I+KL L+ KCRI CKNK+GKSPLD AK+ NR DC+KLLTNMEKLFAIIERDDPIEIEKLFISCEFIRENI TGLNVLEMAMTSNA
Sbjct:  158 RNCNTECENESGNRPIHYASREGHSEIVKLFLQRKCRIDCKNKDGKSPLDFAKEYNRVDCMKLLTNMEKLFAIIERDDPIEIEKLFISCEFIRENIYTGLNVLEMAMTSNA 268

HSP 2 Score: 69.3218 bits (168), Expect = 6.740e-15
Identity = 33/64 (51.56%), Postives = 41/64 (64.06%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            RNCN  CE+KS  RPIHYAS  GHS+I+KLLL   C   C+N++G  P+  A      + VKLL
Sbjct:   59 RNCNTICETKSGDRPIHYASWQGHSEIVKLLLDRNCNTECENESGNRPIHYASWQGHSEIVKLL 122

[Close]

BLAST of SMED30023104 vs. Planmine SMEST
Match: SMESG000019761.1 (SMESG000019761.1)

HSP 1 Score: 188.348 bits (477), Expect = 7.186e-57
Identity = 91/111 (81.98%), Postives = 100/111 (90.09%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCEFIRENICTGLNVLEMAMTSNA 333
            RNCN ECE+KSK RPIHYAS  GHS+ILKLLLR KCRI CKNK+GKSPLD+AK+ N FDCV+LLTNMEKLFAIIERD+ IEIEKLFISC+FIRENI TGLNVL +AMTSNA
Sbjct:  238 RNCNTECETKSKWRPIHYASWKGHSEILKLLLRRKCRIDCKNKDGKSPLDIAKEYNHFDCVELLTNMEKLFAIIERDEAIEIEKLFISCQFIRENIYTGLNVLAIAMTSNA 348

HSP 2 Score: 70.8626 bits (172), Expect = 2.078e-15
Identity = 33/64 (51.56%), Postives = 42/64 (65.62%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            RNCN ECE K   RPIH+ASR GHS+I+KLLL   C   C++K+G+ P+  A      + VKLL
Sbjct:   92 RNCNTECEDKLGWRPIHWASRQGHSEIVKLLLDRNCNTECEDKSGERPIHHASWRGHSEIVKLL 155

HSP 3 Score: 69.3218 bits (168), Expect = 7.793e-15
Identity = 33/64 (51.56%), Postives = 42/64 (65.62%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            RNCN ECE+K  MRPI+ ASR GHS+I+KLLL   C   C++K G  P+  A +    + VKLL
Sbjct:   59 RNCNTECETKWGMRPIYLASRQGHSEIVKLLLDRNCNTECEDKLGWRPIHWASRQGHSEIVKLL 122

HSP 4 Score: 65.0846 bits (157), Expect = 2.061e-13
Identity = 35/80 (43.75%), Postives = 45/80 (56.25%), Query Frame = 1

Query:    1 RNCNVECESKS--------------KMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTN 198
            RNCN ECE+KS              K RPIHYAS  GHS+I+KLLL   C I C++++G  P+  A      + +KLL N
Sbjct:  158 RNCNTECETKSETDRFIMQAGEDKSKWRPIHYASWEGHSEIVKLLLDRNCNIECEDESGNRPIHHASWRGHSEILKLLLN 237

HSP 5 Score: 57.3806 bits (137), Expect = 1.026e-10
Identity = 26/44 (59.09%), Postives = 31/44 (70.45%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKN 132
            RNCN ECE KS  RPIH+AS  GHS+I+KLLL   C   C+ K+
Sbjct:  125 RNCNTECEDKSGERPIHHASWRGHSEIVKLLLDRNCNTECETKS 168

[Close]

BLAST of SMED30023104 vs. Planmine SMEST
Match: SMESG000019761.1 (SMESG000019761.1)

HSP 1 Score: 187.963 bits (476), Expect = 9.331e-57
Identity = 91/111 (81.98%), Postives = 100/111 (90.09%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCEFIRENICTGLNVLEMAMTSNA 333
            RNCN ECE+KSK RPIHYAS  GHS+ILKLLLR KCRI CKNK+GKSPLD+AK+ N FDCV+LLTNMEKLFAIIERD+ IEIEKLFISC+FIRENI TGLNVL +AMTSNA
Sbjct:  238 RNCNTECETKSKWRPIHYASWKGHSEILKLLLRRKCRIDCKNKDGKSPLDIAKEYNHFDCVELLTNMEKLFAIIERDEAIEIEKLFISCQFIRENIYTGLNVLAIAMTSNA 348

HSP 2 Score: 73.9442 bits (180), Expect = 1.778e-16
Identity = 35/66 (53.03%), Postives = 44/66 (66.67%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLLTN 198
            RNCN ECE KSK RPIHYAS  GHS+I+KLLL   C I C++++G  P+  A      + +KLL N
Sbjct:  172 RNCNTECEDKSKWRPIHYASWEGHSEIVKLLLDRNCNIECEDESGNRPIHHASWRGHSEILKLLLN 237

HSP 3 Score: 68.9366 bits (167), Expect = 9.192e-15
Identity = 33/64 (51.56%), Postives = 42/64 (65.62%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            RNCN ECE+K  MRPI+ ASR GHS+I+KLLL   C   C++K G  P+  A +    + VKLL
Sbjct:   59 RNCNTECETKWGMRPIYLASRQGHSEIVKLLLDRNCNTECEDKLGWRPIHWASRQGHSEIVKLL 122

HSP 4 Score: 66.6254 bits (161), Expect = 6.611e-14
Identity = 29/52 (55.77%), Postives = 37/52 (71.15%), Query Frame = 1

Query:    1 RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLA 156
            RNCN ECE K   RPIH+ASR GHS+I+KLLL   C   C++K+G+ P+  A
Sbjct:   92 RNCNTECEDKLGWRPIHWASRQGHSEIVKLLLDRNCNTECEDKSGERPIHHA 143

HSP 5 Score: 58.9214 bits (141), Expect = 3.134e-11
Identity = 33/78 (42.31%), Postives = 42/78 (53.85%), Query Frame = 1

Query:    1 RNCNVECESKS--------------KMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLDLAKQCNRFDCVKLL 192
            RNCN ECE KS              + RPIH+ASR GHS+I+KLLL   C   C++K+   P+  A      + VKLL
Sbjct:  125 RNCNTECEDKSGERPIHHASWRDQIRNRPIHHASRRGHSEIVKLLLDRNCNTECEDKSKWRPIHYASWEGHSEIVKLL 202

The following BLAST results are available for this feature:

BLAST of SMED30023104 vs. Ensembl Human
BLAST of SMED30023104 vs. Ensembl Celegans
BLAST of SMED30023104 vs. Ensembl Fly
BLAST of SMED30023104 vs. Ensembl Zebrafish
BLAST of SMED30023104 vs. Ensembl Xenopus
BLAST of SMED30023104 vs. Ensembl Mouse
BLAST of SMED30023104 vs. UniProt/SwissProt
BLAST of SMED30023104 vs. TrEMBL
BLAST of SMED30023104 vs. Ensembl Cavefish
BLAST of SMED30023104 vs. Ensembl Sea Lamprey
BLAST of SMED30023104 vs. Ensembl Yeast
BLAST of SMED30023104 vs. Ensembl Nematostella
BLAST of SMED30023104 vs. Ensembl Medaka
BLAST of SMED30023104 vs. Planmine SMEST

BLAST of SMED30023104 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ANK1	1.639e-11	42.19	ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492]	[more]
ANK1	1.639e-11	42.19	ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492]	[more]
ANK1	1.640e-11	42.19	ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492]	[more]
ANK3	1.790e-9	34.38	ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]	[more]
ANK3	1.808e-9	34.38	ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]	[more]

BLAST of SMED30023104 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
unc-44	3.691e-7	32.81	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	3.691e-7	32.81	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	3.692e-7	32.81	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	3.692e-7	32.81	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	3.694e-7	32.81	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]

BLAST of SMED30023104 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TrpA1	4.570e-9	39.47	gene:FBgn0035934 transcript:FBtr0331827	[more]
TrpA1	4.615e-9	39.47	gene:FBgn0035934 transcript:FBtr0331826	[more]
TrpA1	4.845e-9	39.47	gene:FBgn0035934 transcript:FBtr0331825	[more]
TrpA1	4.851e-9	39.47	gene:FBgn0035934 transcript:FBtr0331824	[more]
TrpA1	5.143e-9	39.47	gene:FBgn0035934 transcript:FBtr0331823	[more]

BLAST of SMED30023104 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ank1a	4.619e-11	37.50	ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GEN...	[more]
ank1b	1.570e-10	35.94	ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN...	[more]
ank1b	1.578e-10	35.94	ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN...	[more]
ank1b	1.595e-10	35.94	ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN...	[more]
ank1b	1.595e-10	35.94	ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN...	[more]

BLAST of SMED30023104 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ANK1	3.728e-10	40.63	ankyrin 1 [Source:NCBI gene;Acc:613080]	[more]
ANK1	3.728e-10	40.63	ankyrin 1 [Source:NCBI gene;Acc:613080]	[more]
ANK1	3.735e-10	40.63	ankyrin 1 [Source:NCBI gene;Acc:613080]	[more]
ANK1	3.736e-10	40.63	ankyrin 1 [Source:NCBI gene;Acc:613080]	[more]
ANK1	3.736e-10	40.63	ankyrin 1 [Source:NCBI gene;Acc:613080]	[more]

BLAST of SMED30023104 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ank1	1.414e-11	42.19	ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88...	[more]
Ank1	1.485e-11	42.19	ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88...	[more]
Ank1	1.517e-11	42.19	ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88...	[more]
Ank1	1.520e-11	42.19	ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88...	[more]
Ank1	1.520e-11	42.19	ankyrin 1, erythroid [Source:MGI Symbol;Acc:MGI:88...	[more]

BLAST of SMED30023104 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P16157\|ANK1_HUMAN	7.871e-11	42.19	Ankyrin-1 OS=Homo sapiens OX=9606 GN=ANK1 PE=1 SV=...	[more]
sp\|Q02357\|ANK1_MOUSE	1.064e-10	42.19	Ankyrin-1 OS=Mus musculus OX=10090 GN=Ank1 PE=1 SV...	[more]
sp\|G5E8K5\|ANK3_MOUSE	7.158e-9	34.38	Ankyrin-3 OS=Mus musculus OX=10090 GN=Ank3 PE=1 SV...	[more]
sp\|Q8C8R3\|ANK2_MOUSE	7.926e-9	35.94	Ankyrin-2 OS=Mus musculus OX=10090 GN=Ank2 PE=1 SV...	[more]
sp\|O70511\|ANK3_RAT	8.673e-9	34.38	Ankyrin-3 OS=Rattus norvegicus OX=10116 GN=Ank3 PE...	[more]

BLAST of SMED30023104 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A059LBQ3	4.385e-10	37.88	ANK_REP_REGION domain-containing protein (Fragment...	[more]
A0A1A8HDW4	4.268e-9	39.06	Ankyrin 1, erythrocytic (Fragment) OS=Nothobranchi...	[more]
V8NF47	4.450e-9	43.75	Ankyrin-1 OS=Ophiophagus hannah OX=8665 GN=ANK1 PE...	[more]
A0A4Z2J7F7	5.113e-9	40.63	Ankyrin-1 OS=Liparis tanakae OX=230148 GN=Ank1_0 P...	[more]
M7B3Q0	6.658e-9	42.19	Ankyrin-1 OS=Chelonia mydas OX=8469 GN=UY3_11160 P...	[more]

BLAST of SMED30023104 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ank1a	2.831e-11	39.06	ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GEN...	[more]
ank1b	6.097e-11	37.50	ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN...	[more]
ank3b	2.749e-10	35.29	ankyrin 3b [Source:ZFIN;Acc:ZDB-GENE-060621-2]	[more]
ank3a	5.587e-10	35.94	ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]	[more]
ank3a	5.600e-10	35.94	ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]	[more]

BLAST of SMED30023104 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000000095.1	1.301e-10	35.94	pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 g...	[more]
ENSPMAT00000000093.1	1.307e-10	35.94	pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 g...	[more]
ENSPMAT00000007446.1	3.141e-9	40.38	pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1...	[more]
ENSPMAT00000003991.1	1.211e-8	31.65	pep scaffold:Pmarinus_7.0:GL484476:255315:281660:1...	[more]
asap2a	7.292e-8	39.13	ArfGAP with SH3 domain, ankyrin repeat and PH doma...	[more]

BLAST of SMED30023104 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
PHO81	5.902e-7	35.59	Cyclin-dependent kinase (CDK) inhibitor; regulates...	[more]

BLAST of SMED30023104 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO38657	9.542e-8	36.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45485	4.904e-7	40.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49727	6.510e-7	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28510	1.082e-6	34.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26963	4.632e-6	41.30	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SMED30023104 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ank1b	2.250e-11	39.06	ankyrin-1 [Source:NCBI gene;Acc:101157380]	[more]
ENSORLT00000040233.1	2.070e-10	37.50	pep primary_assembly:ASM223467v1:19:16412534:16434...	[more]
ENSORLT00000039903.1	2.575e-10	37.50	pep primary_assembly:ASM223467v1:15:18469388:18484...	[more]
ENSORLT00000006308.2	1.029e-9	35.94	pep primary_assembly:ASM223467v1:1:12516834:125306...	[more]
ank1a	3.767e-9	42.86	ankyrin-1 [Source:NCBI gene;Acc:101174837]	[more]

BLAST of SMED30023104 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000019970.1	3.304e-59	85.59	SMESG000019970.1	[more]
SMESG000010347.1	4.759e-59	83.78	SMESG000010347.1	[more]
SMESG000019959.1	1.720e-57	82.88	SMESG000019959.1	[more]
SMESG000019761.1	7.186e-57	81.98	SMESG000019761.1	[more]
SMESG000019761.1	9.331e-57	81.98	SMESG000019761.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30023104 ID=SMED30023104|Name=SMED30023104|organism=Schmidtea mediterranea sexual|type=transcript|length=334bp
CGCAACTGCAATGTCGAATGTGAGAGCAAATCAAAAATGAGACCAATTCA
CTATGCAAGCCGTAATGGTCATTCAGATATATTGAAATTATTGCTGCGGG
AAAAATGTCGAATCTATTGCAAAAACAAAAACGGAAAGAGTCCACTGGAT
TTGGCAAAGCAATGTAATCGGTTTGATTGCGTGAAATTATTGACTAATAT
GGAGAAATTATTCGCTATCATTGAACGGGATGATCCAATCGAAATTGAAA
AATTGTTCATATCCTGCGAATTCATTAGAGAGAATATTTGTACTGGATTG
AATGTGCTGGAGATGGCAATGACGAGTAATGCTG

protein sequence of SMED30023104-orf-1

>SMED30023104-orf-1 ID=SMED30023104-orf-1|Name=SMED30023104-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=111bp
RNCNVECESKSKMRPIHYASRNGHSDILKLLLREKCRIYCKNKNGKSPLD
LAKQCNRFDCVKLLTNMEKLFAIIERDDPIEIEKLFISCEFIRENICTGL
NVLEMAMTSNA

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000429	neoblast

Vocabulary: **INTERPRO**
Term	Definition
IPR036770	Ankyrin_rpt-contain_sf
IPR002110	Ankyrin_rpt
IPR020683	Ankyrin_rpt-contain_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0005198	structural molecule activity
GO:0005200	structural constituent of cytoskeleton
GO:0008093	cytoskeletal adaptor activity
GO:0019899	enzyme binding
GO:0030507	spectrin binding
GO:0051117	ATPase binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0014731	spectrin-associated cytoskeleton
GO:0016020	membrane
GO:0016323	basolateral plasma membrane
GO:0016529	sarcoplasmic reticulum
GO:0030018	Z disc
GO:0030673	axolemma
GO:0031430	M band
GO:0031672	A band
GO:0042383	sarcolemma
GO:0043005	neuron projection
GO:0045211	postsynaptic membrane

Vocabulary: **biological process**
Term	Definition
GO:0006887	exocytosis
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0007010	cytoskeleton organization
GO:0007165	signal transduction
GO:0010638	positive regulation of organelle organization
GO:0045199	maintenance of epithelial cell apical/basal polarity
GO:0072661	protein targeting to plasma membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002110	Ankyrin repeat	SMART	SM00248	ANK_2a	coord: 11..40 e-value: 0.51 score: 19.4 coord: 44..73 e-value: 170.0 score: 10.7
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 11..43 score: 8.71
None	No IPR available	PFAM	PF13857	Ank_5	coord: 3..52 e-value: 6.9E-9 score: 35.8
None	No IPR available	PANTHER	PTHR45854:SF3	ARFGAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN	coord: 4..69
None	No IPR available	PANTHER	PTHR45854	FAMILY NOT NAMED	coord: 4..69
IPR036770	Ankyrin repeat-containing domain superfamily	GENE3D	G3DSA:1.25.40.20		coord: 1..76 e-value: 4.2E-17 score: 64.2
IPR036770	Ankyrin repeat-containing domain superfamily	SUPERFAMILY	SSF48403	Ankyrin repeat	coord: 2..69
IPR020683	Ankyrin repeat-containing domain	PROSITE	PS50297	ANK_REP_REGION	coord: 1..64 score: 14.132