ATP-binding cassette sub-family A member 1

Overview


Name	ATP-binding cassette sub-family A member 1
Smed ID	SMED30023044
Length (bp)	2501

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30023044

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30023044	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30023044	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30023044	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30023044	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30023044	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30023044	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30023044	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
reproductive organ	SMED30023044	SMESG000032891.1 SMESG000029537.1	Contig8654	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30023044	SMESG000032891.1 SMESG000029537.1	Contig8654	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
epidermis	SMED30023044	SMESG000032896.1 SMESG000029537.1 SMESG000029534.1	dd_Smed_v4_2300_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

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Homology

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:29])

HSP 1 Score: 298.13 bits (762), Expect = 1.355e-84
Identity = 259/881 (29.40%), Postives = 440/881 (49.94%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKW--SPIP--------NGNIPL--ISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWS-SKLIGDSPFWEELRDFVNASQANHNQSNLNSL-KFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF------NNKIKKT--EDFDISLEKNRMNSEQKFDDVLQVINLTKIYNR 2410
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 ++  ++++  +  S++G                +   I+ H+ +A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG+S+T+LEE+F++VA++ + ++ ET +  L P   NR A +GD ++   PF   D  D N      +S    L+S    +    ++G+ L +QQ + L  KR   A+R++KG FA+++LP + + + +    +V P    P++E+ PW+            +  +   ++       G    +N LT         D G  G RCM  +    T  +   E    +W  +P+P        NGN  +   SP C C++   +    +C     G P    R   ++D L +LTG NISDYL+K + ++  K            YGGF   + +T     S+ + D+   ++++  +  ++ +     LNSL +F+  L     +        ++W N+KG+ ++ ++ N+ +N +LR+ L K       YGI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERVS +K  QF+SG+ P +YW+SNF+WD+  Y++P  ++IIIFI F  +SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   TD      N+ILK VFLIFP + LGRG+ID+  N    +  + + +        W++    L ++ +              GV+  ++  +++  +F      N K+     ED D+  E+ R+      +D+L++  LTKIY R
Sbjct: 1098 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEE-SGVDAETSDGTL-PARRNRRA-FGDKQSCLRPFTEDDAADPNDSDIDPESRETDLLSGMDGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWM------------YNEQYTFVSNDAPEDTGTLELLNALT--------KDPG-FGTRCMEGNPIPDTPCQAGEE----EWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSSDKIKKMLPVCPPGAGGLP-PPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNTQALPPSQEVNDAI--KQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNV--------KVWFNNKGWHAISSFLNVINNAILRANLQKGE-NPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELF--TDNKLNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAV-------------EGVVFFLITVLIQYRFFIRPRPVNAKLSPLNDEDEDVRRERQRILDGGGQNDILEIKELTKIYRR 1923

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Match: ABCA7 (ATP binding cassette subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:37])

HSP 1 Score: 286.96 bits (733), Expect = 6.480e-81
Identity = 250/857 (29.17%), Postives = 412/857 (48.07%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------NFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAK---INEETKNEKL--------IPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGN-IP-LISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWSSKLIGDS--PFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYN 2407
             DR+A+++ G+L CCGS +FL+R  G GY L LVK                   +   +K+N  +G      +LL  ++  +P A++  E   +   VLP   ++   F+ LF  LD  +  L    YG+SDTSLEE+F++V ++ A    + + +  + L        +   L        +EN EP     + +Q +  D         R    ++G+ L +QQ+  L +KRF  A+R+++G+FA+++LP L + L +    +V P    PA+ +SP             T Y    Q++F   +  G+      L   L+        E+G+    P +  S+H    PE        + +GN  P   SP C C+  G +     C     G P     +  S + + NLTG N+SD+L+K +P+L R+            YGGF          S + +G S    W  L      +  +    NL +       Q + KI          W N+KG+ SM A+ N  SN +LR+ L     +   + I+  N P+ + +       +    +++ ++I V+F +SF+PASF + L+EERV+ +K  Q + G++P +YW+ NFLWD+  Y++P  I+++IF+AF  ++Y+   N  A +LLL+ YG +I P MYP SFF S PSTA+VVL   NL +G   +M+TF+L++   +D+  +  + ILK+VFLIFP + LGRG+ID+  N     M D + +           WEV  + L ++++   L+ +  ++++       L    +V      +   ED D++ E+ R+       DVL + NLTK+Y 
Sbjct: 1005 GDRVAVVAGGRLCCCGSPLFLRRHLGSGYYLTLVKARLPLTTNEKADTDMEGSVDTRQEKKNGSQGSRVGTPQLLALVQHWVPGARLVEELPHELVLVLPYTGAHDGSFATLFRELDTRLAELRLTGYGISDTSLEEIFLKVVEECAADTDMEDGSCGQHLCTGIAGLDVTLRLKMPPQETALENGEPAGSAPETDQGSGPDA------VGR----VQGWALTRQQLQALLLKRFLLARRSRRGLFAQIVLPALFVGLALVFSLIVPPFGHYPALRLSP-------------TMYGA--QVSFFSEDAPGDPGRARLLEALLQ--------EAGLE--EPPVQHSSHRFSAPEVPAEVAKVLASGNWTPESPSPACQCSRPGARRLLPDCPAAAGGPP-PPQAVTGSGEVVQNLTGRNLSDFLVKTYPRLVRQGLKTKKWVNEVRYGGFSLGGRDPGLPSGQELGRSVEELWALLSPLPGGA-LDRVLKNLTAWAHSLDAQDSLKI----------WFNNKGWHSMVAFVNRASNAILRAHLPPGPARHA-HSITTLNHPLNLTKEQLSEGALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLMGGLSPTLYWLGNFLWDMCNYLVPACIVVLIFLAFQQRAYVAPANLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINGSMATFVLELF--SDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRN---QAMADAFERLGDRQFQSPLRWEVVGKNLLAMVIQGPLFLLFTLLLQH---RSQLLPQPRVRSL--PLLGEEDEDVARERERVVQGATQGDVLVLRNLTKVYR 1803

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Match: ABCA4 (ATP binding cassette subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:34])

HSP 1 Score: 278.87 bits (712), Expect = 3.604e-78
Identity = 253/885 (28.59%), Postives = 424/885 (47.91%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILV---KNFNAQKENFR-------KGISNS---------------GD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHK--------------LLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKE-NQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYR--STHYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSR-----------KLYGGFQF-----VLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLK-FIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEM--EQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKT--------EDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRT 2413
             DRIAII+QG+L C G+ +FLK  FG G  L LV   KN  +Q++          KG S +               GD  +L+  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D           +   +N+N          + P L   +   Q   D ++ S      H               L  G  L+ Q +  L +KRF +  R+ K   A+++LP   + L + L  ++ P    PA+ + PW+   +    +++    ++   L   + N+ G  N    L +    EY          C N + ++  S        ++  KW+ +        SP C C+T    T    C +  +GG P   R   S++ L +LT  NISD+L+K +P L R           + YGG        V+P T      L+G   F  +L   +N S     +     +  F+ +L+    I        ++W N+KG+ ++ ++ N+  N +LR+ L K      +YGI+V + P+ +  EQ ++   L   +  +  +AI VIF +SF+PASFV++L++ERV+ SK  QF+SG++P  YWV+NFLWDIM Y +   +++ IFI F  ++Y   +N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TFIL++ E+     R  N +L+K+ ++FP + LGRG+IDL+   +   +TD YA++      + F W++  + L ++++              GV+  +L  +++  +F ++            ED D++ E+ R+ +     D+L++  LTKIY  T
Sbjct: 1127 GDRIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTCSCSSKGFSTTCPAHVDDLTPEQVLDGDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGPLFAGGAQQKRENVN---------PRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPECPGPQLNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPALTLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRC--LKEGWLPEYP---------CGNSTPWKTPSVSPNITQLFQKQKWTQVNP------SPSCRCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPVVPIT---GEALVG---FLSDLGRIMNVSGGPITREASKEIPDFLKHLETEDNI--------KVWFNNKGWHALVSFLNVAHNAILRASLPKDRSPE-EYGITVISQPLNLTKEQLSEITVLTTSV--DAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSVSAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAITFILELFENNRTLLR-FNAVLRKLLIVFPHFCLGRGLIDLA---LSQAVTDVYARFGEEHSANPFHWDLIGKNLFAMVV-------------EGVVYFLLTLLVQRHFFLSQWIAEPTKEPIVDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGT 1950

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Match: ABCA4 (ATP binding cassette subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:34])

HSP 1 Score: 247.669 bits (631), Expect = 1.724e-68
Identity = 224/803 (27.90%), Postives = 385/803 (47.95%), Query Frame = 2

Query:  167 LQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHK--------------LLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKE-NQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYR--STHYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSR-----------KLYGGFQF-----VLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLK-FIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEM--EQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF--------NNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRT 2413
            +  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D           +   +N+N          + P L   +   Q   D ++ S      H               L  G  L+ Q +  L +KRF +  R+ K   A+++LP   + L + L  ++ P    PA+ + PW+   +    +++    ++   L   + N+ G  N    L +    EY          C N + ++  S        ++  KW+ +        SP C C+T    T    C +  +GG P   R   S++ L +LT  NISD+L+K +P L R           + YGG        V+P T      L+G   F  +L   +N S     +     +  F+ +L+    I        ++W N+KG+ ++ ++ N+  N +LR+ L K      +YGI+V + P+ +  EQ ++   L   +  +  +AI VIF +SF+PASFV++L++ERV+ SK  QF+SG++P  YWV+NFLWDIM Y +   +++ IFI F  ++Y   +N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TFIL++ E+     R  N +L+K+ ++FP + LGRG+IDL+   +   +TD YA++      + F W++  + L ++++              GV+  +L  +++  +F          +    ED D++ E+ R+ +     D+L++  LTKIY  T
Sbjct:    1 MDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGPLFAGGAQQKRENVN---------PRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPECPGPQLNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPALTLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRC--LKEGWLPEYP---------CGNSTPWKTPSVSPNITQLFQKQKWTQVNP------SPSCRCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPVVPIT---GEALVG---FLSDLGRIMNVSGGPITREASKEIPDFLKHLETEDNI--------KVWFNNKGWHALVSFLNVAHNAILRASLPKDRSPE-EYGITVISQPLNLTKEQLSEITVLTTSV--DAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSVSAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAITFILELFENNRTLLR-FNAVLRKLLIVFPHFCLGRGLIDLA---LSQAVTDVYARFGEEHSANPFHWDLIGKNLFAMVV-------------EGVVYFLLTLLVQRHFFLSQWIAEPTKEPIVDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGT 742

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Match: ABCA12 (ATP binding cassette subfamily A member 12 [Source:HGNC Symbol;Acc:HGNC:14637])

HSP 1 Score: 214.157 bits (544), Expect = 9.307e-57
Identity = 237/828 (28.62%), Postives = 386/828 (46.62%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDN----LNALSYGLSDTSLEEVFIRVADDPAKIN----EETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWS----PIPNGNIPLISPECDCNTTGYQICNDPR-SGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPI----EMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVG--SITTMS-TFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYA-KYDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSY--FN-NKIKKT--EDFDISLEKNRMNSEQKFDDVLQVINLTKIYN 2407
            SDRIA + QG L+CCGS  +LK  FGDGY L L K    +  N           +   I+SH+P+A ++ +   +  +VLP     S K SG +++L   +DN    LN   YG+SDT++EEVF+ +  +  K +    E    +K+   N N I+   D+           ++   F D+    L   R  +L  GF LL ++I+ + IKRFH+ +RN KG+ A++ILPI+ +T  + L  L N   S P ++ISP L                     +  + Q     + +P T+ L S      G   + C+N S       +C  +    KW+    PI N  +      C C +   Q C  P+ +  PP  +R   SS  + NLTG  + +YL+    +  +K YGG+ F LP T              ++LR  +    AN                          +  ++W + +GY S+PAY N  +N LLR  ++K       +GI + + P     + EQ+T     ++ +I ++ +A+ ++ G S   ASFV ++V E  + +K+ Q +SGI    YWV+NF++D++ Y++P+   I I   F   ++    N  A  LLL+ +G A    MY  +        AF+     NL  G  SI ++S  + L   +  D T    +E LK++FLIFPQ+  G G+I+LS      +    Y  +Y    +E+   KL ++ +  +    +   + R +IN  L + L++ +  FN + +++T  ED D+  E+ R+ S     D++Q+  LTK Y 
Sbjct: 1544 SDRIAFLEQGGLRCCGSPFYLKEAFGDGYHLTLTKK---KSPNLNANAVCDTMAVTAMIQSHLPEAYLKEDIGGELVYVLP---PFSTKVSGAYLSLLRALDNGMGDLNIGCYGISDTTVEEVFLNLTKESQKNSAMSLEHLTQKKIGNSNANGISTPDDL----------SVSSSNFTDRDDKILT--RGERL-DGFGLLLKKIMAILIKRFHHTRRNWKGLIAQVILPIVFVTTAMGLGTLRNSSNSYPEIQISPSL---------------------YGTSEQTAFYANYHPSTEALVSAMWDFPGIDNM-CLNTS-----DLQCLNKDSLEKWNTSGEPITNFGV------CSC-SENVQEC--PKFNYSPP--HRRTYSSQVIYNLTGQRVENYLISTANEFVQKRYGGWSFGLPLT--------------KDLRFDITGVPANR-------------------------TLAKVWYDPEGYHSLPAYLNSLNNFLLRVNMSKYDAA--RHGIIMYSHPYPGVQDQEQAT-----ISSLI-DILVALSILMGYSVTTASFVTYVVREHQTKAKQLQHISGIGVTCYWVTNFIYDMVFYLVPVAFSIGIIAIFKLPAFYSENNLGAVSLLLLLFGYATFSWMYLLAGLFHETGMAFITYVCVNLFFGINSIVSLSVVYFLSKEKPNDPTLELISETLKRIFLIFPQFCFGYGLIELSQQQSVLDFLKAYGVEYPNETFEM--NKLGAMFVALVSQGTMFFSL-RLLINESLIKKLRLFFRKFNSSHVRETIDEDEDVRAERLRVESGAAEFDLVQLYCLTKTYQ 2264

HSP 2 Score: 51.6026 bits (122), Expect = 7.940e-6
Identity = 35/125 (28.00%), Postives = 59/125 (47.20%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRL-ILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  GK QC GS   +K +FG G+ + + +KN     E   K           F++ H P   ++ + ++   + +P         + +F  L+     LN  ++ +S T+LEEVFI  A D
Sbjct: 2458 RLAIMVNGKFQCIGSLQHIKSRFGRGFTVKVHLKNNKVTMETLTK-----------FMQLHFPKTYLKDQHLSMLEYHVPVTAGG---VANIFDLLETNKTALNITNFLVSQTTLEEVFINFAKD 2568

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Match: abt-2 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q1RS86])

HSP 1 Score: 91.2781 bits (225), Expect = 1.842e-18
Identity = 99/383 (25.85%), Postives = 182/383 (47.52%), Query Frame = 2

Query: 1031 CDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDY-LLKNFPKLSRK----LYGGFQFVLPSTFGWSSKLIGDSP--FWEELRDFVNASQA-NHNQSNLN--SLKFIDYLQKTFKIYGIKTSF---------TRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIF----VIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIG-SKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLG----RGMI 2095
            C C   G+    +       N  R+ T+ D++ +LTG N++ + L+  F +L+        GGF     +    S   I  S   + E ++D   + +  N N + +   + K +D   +   +  +              ++W N+K +   P  +NI SN LLR      A+   D GI   N P+  +  ++ LD  N +    +LA+F    ++  LS IPA F ++LVE+R+  +   Q V G+    YWV+++L+D++ Y + II+I++I++ F    +        AF+LL   +G++ I + Y F    S  + +FV++   +  VG +  ++  +L+ +   D +  P + +   VFL+ PQY+LG    RG++
Sbjct: 1317 CGCEDFGWNCTLEDWKWNETNWLRLNTT-DRIFDLTGRNLTQFRLITRFAQLANTTAPFFLGGFSLGHVNQRAQSQADIDTSKRGWLETIKDIAQSMRIINLNTTGIEPATPKVLDPFAQNITLNQVVNDLLQNLDVRENVKVWFNNKIWPGFPIASNILSNALLRQEDY--AIDPEDLGILTMNHPMN-KTISQTLD-QNALKFTQALAVFRITILLLVLSMIPAGFTVYLVEDRICEALHLQLVGGLRKVTYWVTSYLYDMVVYTLVIIVIMLIYLCFRVSDFTADGATFFAFLLLFFVHGMSTILYAYVFQKAFSVAALSFVLIAIGSYFVGIVCALTVIMLESLMVQDPSLIPAHTVCSIVFLVLPQYNLGIAIFRGLM 1694

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Match: abt-2 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q1RS86])

HSP 1 Score: 91.2781 bits (225), Expect = 1.948e-18
Identity = 99/383 (25.85%), Postives = 182/383 (47.52%), Query Frame = 2

Query: 1031 CDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDY-LLKNFPKLSRK----LYGGFQFVLPSTFGWSSKLIGDSP--FWEELRDFVNASQA-NHNQSNLN--SLKFIDYLQKTFKIYGIKTSF---------TRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIF----VIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIG-SKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLG----RGMI 2095
            C C   G+    +       N  R+ T+ D++ +LTG N++ + L+  F +L+        GGF     +    S   I  S   + E ++D   + +  N N + +   + K +D   +   +  +              ++W N+K +   P  +NI SN LLR      A+   D GI   N P+  +  ++ LD  N +    +LA+F    ++  LS IPA F ++LVE+R+  +   Q V G+    YWV+++L+D++ Y + II+I++I++ F    +        AF+LL   +G++ I + Y F    S  + +FV++   +  VG +  ++  +L+ +   D +  P + +   VFL+ PQY+LG    RG++
Sbjct: 1280 CGCEDFGWNCTLEDWKWNETNWLRLNTT-DRIFDLTGRNLTQFRLITRFAQLANTTAPFFLGGFSLGHVNQRAQSQADIDTSKRGWLETIKDIAQSMRIINLNTTGIEPATPKVLDPFAQNITLNQVVNDLLQNLDVRENVKVWFNNKIWPGFPIASNILSNALLRQEDY--AIDPEDLGILTMNHPMN-KTISQTLD-QNALKFTQALAVFRITILLLVLSMIPAGFTVYLVEDRICEALHLQLVGGLRKVTYWVTSYLYDMVVYTLVIIVIMLIYLCFRVSDFTADGATFFAFLLLFFVHGMSTILYAYVFQKAFSVAALSFVLIAIGSYFVGIVCALTVIMLESLMVQDPSLIPAHTVCSIVFLVLPQYNLGIAIFRGLM 1657

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Match: abt-4 (ABC Transporter family [Source:UniProtKB/TrEMBL;Acc:Q9TXV8])

HSP 1 Score: 78.1814 bits (191), Expect = 1.933e-14
Identity = 51/171 (29.82%), Postives = 93/171 (54.39%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFV 514
             DRIAI++ G+L+CCGS +FLK+++GDGY L +V +  +  +     +S + D     I+ +IP+A + +    + +++L  + ++   F  LF  L++        S+G+S T++EEVF++V       +E    E  I ++++ +     IE  +P   L+DL  Q  V
Sbjct:  794 GDRIAIMAHGQLECCGSPMFLKQQYGDGYHLTIVYDTTSTPD-----VSKTTD----IIREYIPEAHVFSYIGQEATYLL--SATHRPIFPKLFKELEDHQTQCGITSFGVSITTMEEVFLKVGHTA---DERYNYEHGIENDISEM-----IEKDDPI--LQDLRAQVRV 943

HSP 2 Score: 66.2402 bits (160), Expect = 9.766e-11
Identity = 43/165 (26.06%), Postives = 81/165 (49.09%), Query Frame = 2

Query: 1598 LAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILL-LIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFL-IFPQYDLGR 2086
            +A  +I   +   A +  FL+ ER   SK  Q +SGI P+++W++ F+WD   ++I I+    IF  F+  +Y      +  + L  + YG   +P  Y F FF  +    F+++  Y++L G I +++  I+      D  +     +   +F  +FP Y++ +
Sbjct: 1159 IAYGLIVSFAVCVAGYSQFLITERKKKSKHMQLLSGIRPWMFWLTAFIWDAAWFVIRILCFDAIFYIFNITAYTHDFGVMLILTLSFLLYGWTALPFTYWFQFFFESAPKGFMMVTMYHILTGMIGSIAVPIISQTSSLDAGY-----LWSIIFAWLFPTYNISQ 1318

HSP 3 Score: 52.373 bits (124), Expect = 1.665e-6
Identity = 38/127 (29.92%), Postives = 63/127 (49.61%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLIL-VKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPA 385
             +AI+  GK +C GS   +K ++G GY L++ +KN             N  +K    IK     + ++ E + Q +F +P++  +   +S LF  L+    +LN   Y LS T+LE+VFI  + D  
Sbjct: 1649 ELAIMVYGKFRCYGSCQHIKSRYGSGYTLLIRLKN------------RNDAEKTKSTIKQTFRGSVIKEEHVLQLNFDIPRDGDS---WSRLFEKLETVSTSLNWDDYSLSQTTLEQVFIEFSRDAG 1760

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Match: ced-7 (ABC transporter ced-7 [Source:UniProtKB/Swiss-Prot;Acc:P34358])

HSP 1 Score: 76.2554 bits (186), Expect = 7.817e-14
Identity = 50/189 (26.46%), Postives = 106/189 (56.08%), Query Frame = 2

Query: 1547 QSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIF-YGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFL-IFPQYDLGRGMIDLSS 2107
            +ST   +L+   ++++ LA  +I   + + ++FV+FL+EER      QQF++GI+P  ++ ++ ++D + Y +  +I + +F+AF +       + LA ++L  F Y  + +P +Y  SF   +PS A V+L  + +++     ++ F++ +I + DE  +    IL  +F+ + P Y  G  +I +++
Sbjct: 1163 KSTSNSNLLPSQLIDVLLAPMLILIFAMVTSTFVMFLIEERTCQFAHQQFLTGISPITFYSASLIYDGILYSLICLIFLFMFLAFHWM-----YDHLAIVILFWFLYFFSSVPFIYAVSFLFQSPSKANVLLIIWQVVISGAALLAVFLIFMIFNIDEWLK---SILVNIFMFLLPSYAFGSAIITINT 1343

HSP 2 Score: 56.6102 bits (135), Expect = 8.257e-8
Identity = 59/233 (25.32%), Postives = 100/233 (42.92%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISN----------SGDKLLQFIKSHIPDA-KMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFL-----DLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAE 655
            D + I+S GKL   G++ +LK+KFG GY L +V + N  K      +++           G+   Q I+  +P+A K E   + Q    +   +  S  F  +   L  ++  L   S+GLS  +LE+VFI + D   K     +N ++  ++ N           EP L     D +   + A   + L+        K   G   +  Q I +  K+F Y++RN   +F +
Sbjct:  799 DWVFIMSHGKLVASGTNQYLKQKFGTGYLLTVVLDHNGDKRKMAVILTDVCTHYVKEAERGEMHGQQIEIILPEARKKEFVPLFQALEAIQDRNYRSNVFDNMPNTLKSQLATLEMRSFGLSLNTLEQVFITIGDKVDKAIASRQNSRISHNSRN---------ASEPSLKPAGYDTQSSTKSADSYQKLMDSQARGPEK--SGVAKMVAQFISIMRKKFLYSRRNWAQLFTQ 1020

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Match: ced-7 (ABC transporter ced-7 [Source:UniProtKB/Swiss-Prot;Acc:P34358])

HSP 1 Score: 76.2554 bits (186), Expect = 8.310e-14
Identity = 50/189 (26.46%), Postives = 106/189 (56.08%), Query Frame = 2

Query: 1547 QSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIF-YGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFL-IFPQYDLGRGMIDLSS 2107
            +ST   +L+   ++++ LA  +I   + + ++FV+FL+EER      QQF++GI+P  ++ ++ ++D + Y +  +I + +F+AF +       + LA ++L  F Y  + +P +Y  SF   +PS A V+L  + +++     ++ F++ +I + DE  +    IL  +F+ + P Y  G  +I +++
Sbjct: 1109 KSTSNSNLLPSQLIDVLLAPMLILIFAMVTSTFVMFLIEERTCQFAHQQFLTGISPITFYSASLIYDGILYSLICLIFLFMFLAFHWM-----YDHLAIVILFWFLYFFSSVPFIYAVSFLFQSPSKANVLLIIWQVVISGAALLAVFLIFMIFNIDEWLK---SILVNIFMFLLPSYAFGSAIITINT 1289

HSP 2 Score: 56.6102 bits (135), Expect = 7.878e-8
Identity = 59/233 (25.32%), Postives = 100/233 (42.92%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISN----------SGDKLLQFIKSHIPDA-KMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFL-----DLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAE 655
            D + I+S GKL   G++ +LK+KFG GY L +V + N  K      +++           G+   Q I+  +P+A K E   + Q    +   +  S  F  +   L  ++  L   S+GLS  +LE+VFI + D   K     +N ++  ++ N           EP L     D +   + A   + L+        K   G   +  Q I +  K+F Y++RN   +F +
Sbjct:  745 DWVFIMSHGKLVASGTNQYLKQKFGTGYLLTVVLDHNGDKRKMAVILTDVCTHYVKEAERGEMHGQQIEIILPEARKKEFVPLFQALEAIQDRNYRSNVFDNMPNTLKSQLATLEMRSFGLSLNTLEQVFITIGDKVDKAIASRQNSRISHNSRNA---------SEPSLKPAGYDTQSSTKSADSYQKLMDSQARGPEK--SGVAKMVAQFISIMRKKFLYSRRNWAQLFTQ 966

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Match: CG34120 (gene:FBgn0083956 transcript:FBtr0343018)

HSP 1 Score: 90.8929 bits (224), Expect = 3.317e-18
Identity = 80/285 (28.07%), Postives = 141/285 (49.47%), Query Frame = 2

Query: 1274 ELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEM----SLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYI 2116
            E R F N SQ +++   LNS  + +Y ++ +  YG+  S   +W N+KGY SM A+ N  ++ LLR+ +N S     +  I   N P ++     F +L    IL      S+   ++     + AS  ++LV ERV+G K QQ + G++   YW+   +WD +  ++ +I+ +++ + F    ++  +  +  I L + +  A +P ++      S  S A V +   NL+V  +T     IL ++ D    +      L + FLIFP + LG G ++L  NY+
Sbjct: 1289 ECRVF-NTSQQSYDWV-LNS--WGEYSERRYGGYGLNGSGATVWYNNKGYHSMMAWLNDLNSELLRTTMNDS-----ESSILTLNEPWKL----GFAELSTSSILRQAGDGSMVFILLIAFGLVVASGSVYLVNERVNGEKLQQRLCGVSAVTYWLVALVWDYLVMVLGLIVCLVVILMFGMPVFVDRQQLVGIIGLSLAFSFACVPSVHVAEKIFSDSSIAIVSIFCANLIVPLVTMGIILILGVVGD-GPAWDDWRHALNQAFLIFPIHALGDGFLELCKNYM 1559

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Match: CG34120 (gene:FBgn0083956 transcript:FBtr0299591)

HSP 1 Score: 90.8929 bits (224), Expect = 3.484e-18
Identity = 80/285 (28.07%), Postives = 141/285 (49.47%), Query Frame = 2

Query: 1274 ELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEM----SLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYI 2116
            E R F N SQ +++   LNS  + +Y ++ +  YG+  S   +W N+KGY SM A+ N  ++ LLR+ +N S     +  I   N P ++     F +L    IL      S+   ++     + AS  ++LV ERV+G K QQ + G++   YW+   +WD +  ++ +I+ +++ + F    ++  +  +  I L + +  A +P ++      S  S A V +   NL+V  +T     IL ++ D    +      L + FLIFP + LG G ++L  NY+
Sbjct: 1272 ECRVF-NTSQQSYDWV-LNS--WGEYSERRYGGYGLNGSGATVWYNNKGYHSMMAWLNDLNSELLRTTMNDS-----ESSILTLNEPWKL----GFAELSTSSILRQAGDGSMVFILLIAFGLVVASGSVYLVNERVNGEKLQQRLCGVSAVTYWLVALVWDYLVMVLGLIVCLVVILMFGMPVFVDRQQLVGIIGLSLAFSFACVPSVHVAEKIFSDSSIAIVSIFCANLIVPLVTMGIILILGVVGD-GPAWDDWRHALNQAFLIFPIHALGDGFLELCKNYM 1542

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Match: CG34120 (gene:FBgn0083956 transcript:FBtr0110827)

HSP 1 Score: 90.8929 bits (224), Expect = 3.491e-18
Identity = 80/285 (28.07%), Postives = 141/285 (49.47%), Query Frame = 2

Query: 1274 ELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEM----SLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYI 2116
            E R F N SQ +++   LNS  + +Y ++ +  YG+  S   +W N+KGY SM A+ N  ++ LLR+ +N S     +  I   N P ++     F +L    IL      S+   ++     + AS  ++LV ERV+G K QQ + G++   YW+   +WD +  ++ +I+ +++ + F    ++  +  +  I L + +  A +P ++      S  S A V +   NL+V  +T     IL ++ D    +      L + FLIFP + LG G ++L  NY+
Sbjct: 1288 ECRVF-NTSQQSYDWV-LNS--WGEYSERRYGGYGLNGSGATVWYNNKGYHSMMAWLNDLNSELLRTTMNDS-----ESSILTLNEPWKL----GFAELSTSSILRQAGDGSMVFILLIAFGLVVASGSVYLVNERVNGEKLQQRLCGVSAVTYWLVALVWDYLVMVLGLIVCLVVILMFGMPVFVDRQQLVGIIGLSLAFSFACVPSVHVAEKIFSDSSIAIVSIFCANLIVPLVTMGIILILGVVGD-GPAWDDWRHALNQAFLIFPIHALGDGFLELCKNYM 1558

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Match: ABCA (gene:FBgn0031170 transcript:FBtr0332488)

HSP 1 Score: 87.4261 bits (215), Expect = 3.672e-17
Identity = 70/212 (33.02%), Postives = 104/212 (49.06%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNK 637
             DRIAI+  G+L+C G+S FLK+++G GYRLI VK  + +            +++   +  +IP  K E +   + S+ LP  DS S KF  +F  L+E+ D L+   YG+  TS+EEVF++V  +               DN   I    +I N       ED N+    D       F+ N +LL+G  LL  Q   + +K+F Y  RNK
Sbjct:  712 GDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVKRDDCET-----------NEVTALLNKYIPGLKPECDIGAELSYQLP--DSASAKFEEMFGQLEEQSDELHLNGYGVGITSMEEVFMKVGAE--------------KDNTGNIKDQHEIMNGGSGFRGEDDNESVQSDGI-----FSENRRLLQGLQLLSNQWKAMLLKKFLYTWRNK 891

HSP 2 Score: 77.0258 bits (188), Expect = 5.673e-14
Identity = 78/296 (26.35%), Postives = 136/296 (45.95%), Query Frame = 2

Query: 1280 RDFVNASQANHNQSNLNSLKFIDY---LQKTFKI-----YGIKTSFTR----IWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETF--RPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYN 2125
             D   +  +N+      +  F DY   L KT ++     Y +  + T      W N++   + P   N+  N +       S+VK     I V+N P+    ST    L     L   LA  + F + F+ + +++FL++ER S +K  QFV G+  + +W+S F+ D   YI+  +I++I  + F             + LLL+ +G A++P +Y  S F   P+T F  ++  N+  G    M+ FI+ ++  + E F  + T +IL  +F IFP + L   +  + +N    N
Sbjct:  956 EDLARSYGSNYGLELTGTQGFEDYILDLGKTIQVRINSRYLVAATITESKITAWLNNQALHTAPLTVNMVHNAIADKLF-GSSVK-----IQVTNAPLPYTTSTLLSQLSTGNNLGTQLASNLCFCMCFVSSIYILFLIKERESRAKLLQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGLSTFGELGRYYLLLLLFGFAVLPFIYIMSLFFREPATGFARVSIVNIFCG----MALFIVVVVM-SSELFDTKDTADILGWIFRIFPHFSLAMSLNKVYTNTATRN 1240

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Match: ABCA (gene:FBgn0031170 transcript:FBtr0332489)

HSP 1 Score: 87.4261 bits (215), Expect = 3.822e-17
Identity = 70/212 (33.02%), Postives = 104/212 (49.06%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNK 637
             DRIAI+  G+L+C G+S FLK+++G GYRLI VK  + +            +++   +  +IP  K E +   + S+ LP  DS S KF  +F  L+E+ D L+   YG+  TS+EEVF++V  +               DN   I    +I N       ED N+    D       F+ N +LL+G  LL  Q   + +K+F Y  RNK
Sbjct:  712 GDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVKRDDCET-----------NEVTALLNKYIPGLKPECDIGAELSYQLP--DSASAKFEEMFGQLEEQSDELHLNGYGVGITSMEEVFMKVGAE--------------KDNTGNIKDQHEIMNGGSGFRGEDDNESVQSDGI-----FSENRRLLQGLQLLSNQWKAMLLKKFLYTWRNK 891

HSP 2 Score: 76.6406 bits (187), Expect = 7.243e-14
Identity = 78/296 (26.35%), Postives = 136/296 (45.95%), Query Frame = 2

Query: 1280 RDFVNASQANHNQSNLNSLKFIDY---LQKTFKI-----YGIKTSFTR----IWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETF--RPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYN 2125
             D   +  +N+      +  F DY   L KT ++     Y +  + T      W N++   + P   N+  N +       S+VK     I V+N P+    ST    L     L   LA  + F + F+ + +++FL++ER S +K  QFV G+  + +W+S F+ D   YI+  +I++I  + F             + LLL+ +G A++P +Y  S F   P+T F  ++  N+  G    M+ FI+ ++  + E F  + T +IL  +F IFP + L   +  + +N    N
Sbjct:  956 EDLARSYGSNYGLELTGTQGFEDYILDLGKTIQVRINSRYLVAATITESKITAWLNNQALHTAPLTVNMVHNAIADKLF-GSSVK-----IQVTNAPLPYTTSTLLSQLSTGNNLGTQLASNLCFCMCFVSSIYILFLIKERESRAKLLQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGLSTFGELGRYYLLLLLFGFAVLPFIYIMSLFFREPATGFARVSIVNIFCG----MALFIVVVVM-SSELFDTKDTADILGWIFRIFPHFSLAMSLNKVYTNTATRN 1240

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Match: abca4a (ATP-binding cassette, sub-family A (ABC1), member 4a [Source:ZFIN;Acc:ZDB-GENE-050517-3])

HSP 1 Score: 317.775 bits (813), Expect = 2.138e-91
Identity = 248/876 (28.31%), Postives = 416/876 (47.49%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRK-GISNSGD--------------------------------KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD--PAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINP------LTDRLESEYRSD--LGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSR-----------KLYGGFQF--VLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLK-FIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKT----EDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTF 2416
            SDR+AIISQG+L CCGS +FLK   G G+ L LV+    Q    RK G  +  D                                 +   +  H+P+A++      + +F+LP        ++ LF  L+E + ++   S+G+SDTSLEEVF++V  D   A IN  +  ++    + N  +   ++ ++E                        R  + ++GF L+ +Q   L IKRFH+  R+ K   A+++LP   + + +    +V P    P++ +SPW+     R     TF+  E Q+        G      P      + D    EY  +    E  +  +NP +             N++W+ I        SP C C+T    T   +C +   G PP   RI ++ D L +LTG NISDYL+K +P L R           + YGG      LP       K I ++    ++   +N +   +++  L+    F+ Y++    +        ++W N+KG+ +M A+ N+ +N  +        V   +YGI+  N P+ + +       V    ++  +AI VIF +SF+PA FV++L++ERV+ +K  QFVSG++P VYW +NF WD++ Y +   +++ IFIAFD + Y    N  A I LL+ YG ++ P MYP S+  + PSTA+V L+  NL +G  ++  TFILD+ + T+  ++  N++LKK  L+FP + LGRG+ID++ N     + D YA++      D F W+   E L  + +   +++         ++N ++     + ++ +  KK     ED D++ E+ R+      +D+LQ+ +L+K Y  TF
Sbjct: 1145 SDRVAIISQGRLYCCGSPLFLKNCLGAGFYLTLVRRIKEQPAPVRKEGQCDCTDDCSCKCSLCTKFKASDTEKPRVSERQMEGNIESITALVHHHVPEARLIEVIGQELTFLLPSRAFKHRSYASLFRELEETLADMGLSSFGVSDTSLEEVFLKVTADGEAAHINTASDTDR---SHANGQSNSANVISKE-----------------------GRGSQQVKGFFLVVKQFFALLIKRFHHTTRSGKDFLAQIVLPASFVFISLMFTLIVPPFGEYPSLTLSPWMY---GRQF---TFFSNE-QMQSPDMRYFGEVLLNRPGFGTRCMVDEPLEEYPCNNITTEWEMPLVNPMLIEM--------LSNSEWTDISP------SPSCQCSTPNKLTMLPVCPEGAGGLPPPQ-RIQSTGDMLMDLTGRNISDYLVKTYPNLIRTSLKSKYWVNEQRYGGISVGGRLP-VLNLDPKSIQNAA--AQIGRLLNVTGGRYSKLALDEFATFLRYMETENNV--------KVWFNNKGWHAMVAFMNV-ANNAILRANLPPGVDLNEYGITAINHPLNLTKEQLSEVTVLTTSVDAVVAINVIFAMSFVPAGFVLYLIQERVTQAKHLQFVSGVSPLVYWTANFFWDMINYSVSAAMVVGIFIAFDKKCYTSPGNLQALIALLMLYGWSVTPMMYPMSYIFNVPSTAYVSLSCINLFIGINSSAITFILDLFDSTEALYK-CNQVLKKALLVFPHFCLGRGLIDMAMNQA---VMDVYARFGEDFSLDPFSWDFVGENLTFMAVEGFVYF---------ILNILIQYRFFLDHWMSDFKKPPITDEDVDVAKERERIYKGGSSNDILQIKDLSKTYTGTF 1947

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Match: abca4b (ATP-binding cassette, sub-family A (ABC1), member 4b [Source:ZFIN;Acc:ZDB-GENE-050517-4])

HSP 1 Score: 312.383 bits (799), Expect = 1.293e-89
Identity = 252/872 (28.90%), Postives = 419/872 (48.05%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQ--KENF--------------------------RKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQA-FVDKSLIS-LNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCF------------PEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKL-----------SRKLYGGFQFVLPSTFGWSSKLIGDSP-----FWEELRDFVNASQANHNQSNLNSLK-FIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNR 2410
            SDR+AIIS+GKL C GS +FLK  FG G+ L LV+    Q  KEN                            + +  + + +   I  H+P+AK+      + +++LP        ++ LF  L+E + ++   S+G+SDTSLEE+F++V  D      E  N  + P+      +    +N   F+    L + A  V  SL S  +  R  + ++GF L+ +Q   L +KRFH+A R+ K   A+++LP   + + +    +V P    P + ++PW+  P               Q  F     + N+   +P           D G  G RCM      +  + C             PE  N   SP  +   P  SP C+C+T    T   +C     G PP   R   + D L ++T  NISDYL+K + KL           + + YGG       + G    ++   P      + +L   +N     +++S ++ L+ F+ Y++  + +        ++W N+KG+ +M ++ N+ +N +LR+ L   A    DYGI+  N P+ + +       V    ++  +AI VIF +SFIPASFV++L++ERV+ +K  QFVSG++P VYW +NF WD++ Y +   +++ IF+ FD + Y    N  A I LL  YG ++ P MYP S+  + PSTA+V L+  NL +G  ++  TFIL++ E+ + +    NE+LKKV L+FP + LGRG+ID++ N     +TD YA++      D F W    + L  + +   +++I  +     +I    +    +S +   +   ED D++ E+ R+      +D+L + +L+K Y R
Sbjct: 1178 SDRVAIISKGKLHCSGSPLFLKNCFGVGFYLTLVRRMKDQRKKENECDCASECSCTCSTCTRYKEESQALQPERVLDGNVESITTLIHHHVPEAKLIEMIGQEMTYLLPNKGFKYRAYASLFRELEETLGDMGLSSFGISDTSLEEIFLKVTAD-----GEAANSSVTPEQW----MLQQRKNGNGFMKDTGLAEDANGVGASLESDSSEGRASRQVKGFSLVLKQFHALLVKRFHHATRSHKDFLAQIVLPASFVLIALVFTMIVPPFGEYPCLTLTPWMYGP---------------QFTF-----ISNEQPSHPKMKHFIQTLLKDPG-MGTRCMANQPLENI-FTCLNSSSDWEVPPVSPEVSNILSSPEWDSRNP--SPSCECSTDLKLTMLPMCPAGAGGLPPRQ-RKEPTGDILLDMTNRNISDYLVKTYTKLIKTSLKSKYWVNEQRYGGI------SVGGRLPILDVDPEEIQNIFSQLGRMMNIRGGRYSKSAMDELETFLHYMESEYNV--------KVWYNNKGWHAMASFLNVANNAILRAYLPPHA-NPSDYGITAINHPLNLTKEQLSEVTVLTTSVDAVVAICVIFAMSFIPASFVLYLIQERVTKAKHLQFVSGVSPLVYWFANFFWDMLNYSVSTAMVVAIFVGFDKKCYTSPTNLPALIALLCLYGWSVTPMMYPLSYMFNVPSTAYVSLSCINLFIGINSSAITFILELFEN-NRSLLMFNEVLKKVLLVFPHFCLGRGLIDMAMNQA---VTDVYARFGEEFSMDPFRWNFVGKNLFCMAVEGFVYFIFNL-----LIQYKFFLHHWISDYGMSLGTDEDDDVAQERERIYKGGNKNDILLIRDLSKTYRR 1991

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Match: abca1b (ATP-binding cassette, sub-family A (ABC1), member 1B [Source:ZFIN;Acc:ZDB-GENE-030131-9826])

HSP 1 Score: 301.597 bits (771), Expect = 4.785e-86
Identity = 263/915 (28.74%), Postives = 446/915 (48.74%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG---DK-------------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQ--EPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCM-NPSIYRSTHYRCFPEYKNNKWSP--IPNGNIPLI----------SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIY--GIKT-SFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIK--------KTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLC 2497
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 +F  + +N  +  S++G   D+             + + I  H+P A+M  +   + ++VLP   + +  F  LF +LD+ + +L   SYG+SDT+LEE+F++VA+D + ++ E  ++  +P    R   +G       +P    D  D N+     +S     +S +  +    ++G+ L +QQ + L  KR  YA+R++KG FA+++LP + + + +    +V P    P++ ++PW+                E Q  F            +  T +L      D G  G RCM   SI  +    C     + +WS   +P   I ++          SP C+C+  G +     C     G PP   +I + ++ L NLTG NISDYL+K + ++  K            YGGF     ST     +++   P  EE+ D ++  +    Q   +S    D   K+   +  G+ T +  +IW N+KG+ S+ A+ N+ +N +LR+ L        ++GI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERV+ +K  QF+SG+ PY+YW++NFLWD+  Y++P  ++I+IF+ F  ++Y+ + N     LLL+ YG +I P MYP SF    PSTA+VVL + N+L+G   ++STF++++  + +      N+ILK V LIFP + LGRG+ID+  N    +  + + +       +W++  + L ++ +              GV+  ++  +++  +F               ED D++ E+ R+ S     D+L++  LTK+Y R                    QK AV+ LC
Sbjct: 1100 GDRIAIISHGKLCCVGSSLFLKTQLGTGYYLTLVKKNTEPSLSSCRNSSSTVSFVKKDDNASESSSDAGLGSDQESEAATAIVDVTIISRLILKHVPAARMVEDQGHEITYVLPYESAKNGAFVELFHDLDDRLADLGISSYGVSDTTLEEIFLKVAED-SGVDTEMLSDGTLPVRRQRRHAFGADHQSCLKPLTEDDSFDCNESEGDPESKETDYLSGSDGKGSYQVKGWSLKRQQFVALLWKRLLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLALNPWMY---------------EEQFMF-----FSEDAPYDVSTHKLLRALFDDPG-FGTRCMKGESIPDAP---C--TMGDEEWSTPEVPESIIEILTTRNWTMNDPSPACECSCNGKKKMLPECPAGAGGLPPPQIKI-SETETLQNLTGRNISDYLVKTYAQIIGKSLKNKIWVNEFRYGGFSLGARST-----QVL---PPAEEIDDAISRVREIF-QLGKDSGSAADRFLKSLSAFINGLDTKNNVKIWFNNKGWHSIGAFLNVMNNGILRANLPPGKDPS-EFGITAYNHPLNLTKEQLSQVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPYLYWLANFLWDMCNYVVPATLVILIFVCFQQKAYVSATNLPVLALLLLLYGWSITPLMYPASFLFKIPSTAYVVLTSVNILIGINGSISTFVMELFGNHE--IGGINDILKNVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFRSPLEWDMVGKNLFAMAV-------------EGVVFFIITVLIQYRFFFEPKSLCPKLSPIGEEDEDVARERQRIMSGAGQGDILELRQLTKVYKR-------------------KQKPAVDRLC 1942

HSP 2 Score: 51.2174 bits (121), Expect = 5.862e-6
Identity = 34/122 (27.87%), Postives = 60/122 (49.18%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVA 373
            R+AI+  G+ +C GS   LK +FGDGY +IL             G       +++FI+S +P + ++ +      + LP   S+    + +F  L +  + L    Y +S T+L++VF+  A
Sbjct: 2122 RMAIMVNGRFRCLGSVQHLKNRFGDGYTIILRV----------AGPDPDLQPVMKFIESELPGSTLKEKHRNMLQYQLP---SSLTSLAHIFSILAKNKEFLRIEDYSVSQTTLDQVFVNFA 2230

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Match: abca4b (ATP-binding cassette, sub-family A (ABC1), member 4b [Source:ZFIN;Acc:ZDB-GENE-050517-4])

HSP 1 Score: 300.056 bits (767), Expect = 1.590e-85
Identity = 243/853 (28.49%), Postives = 398/853 (46.66%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQ--KENF--------------------------RKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCF------------PEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNR 2410
            SDR+AIIS+GKL C GS +FLK  FG G+ L LV+    Q  KEN                            + +  + + +   I  H+P+AK+      + +++LP        ++ LF  L+E + ++   S+G+SDTSLEE+F++V  D    N        +  + N +    + ++ E                        R  + ++GF L+ +Q   L +KRFH+A R+ K   A+++LP   + + +    +V P    P + ++PW+  P               Q  F     + N+   +P           D G  G RCM      +  + C             PE  N   SP  +   P  SP C+C+T    T   +C     G PP   R   + D L ++T  NISDYL+K + KL +       +V    +G  S + G  P  +     V+  +  +  S L          +   I G       +W N+KG+ +M ++ N+ +N +LR+ L   A    DYGI+  N P+ + +       V    ++  +AI VIF +SFIPASFV++L++ERV+ +K  QFVSG++P VYW +NF WD++ Y +   +++ IF+ FD + Y    N  A I LL  YG ++ P MYP S+  + PSTA+V L+  NL +G  ++  TFIL++ E+ + +    NE+LKKV L+FP + LGRG+ID++ N     +TD YA++      D F W    + L  + +   +++I  +     +I    +    +S +   +   ED D++ E+ R+      +D+L + +L+K Y R
Sbjct: 1097 SDRVAIISKGKLHCSGSPLFLKNCFGVGFYLTLVRRMKDQRKKENECDCASECSCTCSTCTRYKEESQALQPERVLDGNVESITTLIHHHVPEAKLIEMIGQEMTYLLPNKGFKYRAYASLFRELEETLGDMGLSSFGISDTSLEEIFLKVTADGEAANSSIMCVSGLVTDANGVGASLESDSSE-----------------------GRASRQVKGFSLVLKQFHALLVKRFHHATRSHKDFLAQIVLPASFVLIALVFTMIVPPFGEYPCLTLTPWMYGP---------------QFTF-----ISNEQPSHPKMKHFIQTLLKDPG-MGTRCMANQPLENI-FTCLNSSSDWEVPPVSPEVSNILSSPEWDSRNP--SPSCECSTDLKLTMLPMCPAGAGGLPPRQ-RKEPTGDILLDMTNRNISDYLVKTYTKLIKTSLKSKYWVNEQRYGGIS-VGGRLPILD-----VDPEEIQNIFSQLG---------RMMNIRGAFNVLLYVWYNNKGWHAMASFLNVANNAILRAYLPPHA-NPSDYGITAINHPLNLTKEQLSEVTVLTTSVDAVVAICVIFAMSFIPASFVLYLIQERVTKAKHLQFVSGVSPLVYWFANFFWDMLNYSVSTAMVVAIFVGFDKKCYTSPTNLPALIALLCLYGWSVTPMMYPLSYMFNVPSTAYVSLSCINLFIGINSSAITFILELFEN-NRSLLMFNEVLKKVLLVFPHFCLGRGLIDMAMN---QAVTDVYARFGEEFSMDPFRWNFVGKNLFCMAVEGFVYFIFNL-----LIQYKFFLHHWISDYGMSLGTDEDDDVAQERERIYKGGNKNDILLIRDLSKTYRR 1876

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Match: abca1b (ATP-binding cassette, sub-family A (ABC1), member 1B [Source:ZFIN;Acc:ZDB-GENE-030131-9826])

HSP 1 Score: 297.36 bits (760), Expect = 1.282e-84
Identity = 263/926 (28.40%), Postives = 446/926 (48.16%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG---DK------------------------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQ--EPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCM-NPSIYRSTHYRCFPEYKNNKWSP--IPNGNIPLI----------SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIY--GIKT-SFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIK--------KTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLC 2497
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 +F  + +N  +  S++G   D+                        + + I  H+P A+M  +   + ++VLP   + +  F  LF +LD+ + +L   SYG+SDT+LEE+F++VA+D + ++ E  ++  +P    R   +G       +P    D  D N+     +S     +S +  +    ++G+ L +QQ + L  KR  YA+R++KG FA+++LP + + + +    +V P    P++ ++PW+                E Q  F            +  T +L      D G  G RCM   SI  +    C     + +WS   +P   I ++          SP C+C+  G +     C     G PP   +I + ++ L NLTG NISDYL+K + ++  K            YGGF     ST     +++   P  EE+ D ++  +    Q   +S    D   K+   +  G+ T +  +IW N+KG+ S+ A+ N+ +N +LR+ L        ++GI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERV+ +K  QF+SG+ PY+YW++NFLWD+  Y++P  ++I+IF+ F  ++Y+ + N     LLL+ YG +I P MYP SF    PSTA+VVL + N+L+G   ++STF++++  + +      N+ILK V LIFP + LGRG+ID+  N    +  + + +       +W++  + L ++ +              GV+  ++  +++  +F               ED D++ E+ R+ S     D+L++  LTK+Y R                    QK AV+ LC
Sbjct: 1100 GDRIAIISHGKLCCVGSSLFLKTQLGTGYYLTLVKKNTEPSLSSCRNSSSTVSFVKKDDNASESSSDAGLGSDQESEAATAIGTSWPESPVVPVDVTIISRLILKHVPAARMVEDQGHEITYVLPYESAKNGAFVELFHDLDDRLADLGISSYGVSDTTLEEIFLKVAED-SGVDTEMLSDGTLPVRRQRRHAFGADHQSCLKPLTEDDSFDCNESEGDPESKETDYLSGSDGKGSYQVKGWSLKRQQFVALLWKRLLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLALNPWMY---------------EEQFMF-----FSEDAPYDVSTHKLLRALFDDPG-FGTRCMKGESIPDAP---C--TMGDEEWSTPEVPESIIEILTTRNWTMNDPSPACECSCNGKKKMLPECPAGAGGLPPPQIKI-SETETLQNLTGRNISDYLVKTYAQIIGKSLKNKIWVNEFRYGGFSLGARST-----QVL---PPAEEIDDAISRVREIF-QLGKDSGSAADRFLKSLSAFINGLDTKNNVKIWFNNKGWHSIGAFLNVMNNGILRANLPPGKDPS-EFGITAYNHPLNLTKEQLSQVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPYLYWLANFLWDMCNYVVPATLVILIFVCFQQKAYVSATNLPVLALLLLLYGWSITPLMYPASFLFKIPSTAYVVLTSVNILIGINGSISTFVMELFGNHE--IGGINDILKNVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFRSPLEWDMVGKNLFAMAV-------------EGVVFFIITVLIQYRFFFEPKSLCPKLSPIGEEDEDVARERQRIMSGAGQGDILELRQLTKVYKR-------------------KQKPAVDRLC 1953

HSP 2 Score: 51.6026 bits (122), Expect = 5.622e-6
Identity = 34/122 (27.87%), Postives = 60/122 (49.18%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVA 373
            R+AI+  G+ +C GS   LK +FGDGY +IL             G       +++FI+S +P + ++ +      + LP   S+    + +F  L +  + L    Y +S T+L++VF+  A
Sbjct: 2133 RMAIMVNGRFRCLGSVQHLKNRFGDGYTIILRV----------AGPDPDLQPVMKFIESELPGSTLKEKHRNMLQYQLP---SSLTSLAHIFSILAKNKEFLRIEDYSVSQTTLDQVFVNFA 2241

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 316.235 bits (809), Expect = 7.709e-91
Identity = 255/867 (29.41%), Postives = 432/867 (49.83%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN-----------------AQKENFRKGISNSG---------------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-------DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--CMNPSIYRSTHY---RCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF------NNKIKKT--EDFDISLEKNRMNSEQKFDDVLQVINLTKIY 2404
             DRIAIIS GKL C GSS+FLK + G GY L LVK  N                  ++++  +  S++G                       +   I  H+P+A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VADD   ++ ET +  L P    R A +GD ++   PF + +       D++ ++     L  ++   +++L + + L++QQ   L  KR  YAKR++KG FA+++LP + + + +    +V P    P++E+ PW+   +       TF+  +        +  G +  +  L D+         G S ++  C       ST +        + N  W+      +   SP C+C++   +    IC  P +GG P   R   +SD L NLTG NISDYL+K + ++  K YGGF                           + AS +     N   +  I++++K  ++  ++  ++ +W N+KG+ ++ A+ N+ +N +LRS+L +       YGI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERVS +K  Q +SG+ P +YW++NF+WD+  Y++P  ++IIIFI F   SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   T+      NEILK V LIFP + LGRG+ID+  N    +  + + +        W++    L ++ +              GV+   +  M++  +F      N K+     ED D++ E+ R+N E   +D+L++  LTKIY
Sbjct: 1052 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKRDNDSSLSSCRNSSSTMSYLKKEDSVSQSSSDAGLGSDHESDTMTIGKYKSLTDVSAISNLINKHVPEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGIADTTLEEIFLKVADDTG-VDAETSDGTL-PARRKRYA-FGDHQSCLRPFTEDDAFDTNDSDMDPESRETDYLSGIDGKGSYQL-KSWNLMRQQFTALLWKRLLYAKRSRKGFFAQIVLPAVFVLIALVFSLIVPPFGKYPSLELEPWMYDEQY------TFFSNDA------PDDQGTQALLKALIDKPGFGTACMEGHSVMKVSCSGEEEEWSTQFVSQSVMDLFLNGNWT------MENPSPSCECSSDKRKKMLPIC-PPGAGGLPPFQRRQNTSDILQNLTGRNISDYLVKTYSQIIEKRYGGFS--------------------------LGASNSPALPPNEEVVASINHIKKRLELPQVEYLYSVVWFNNKGWHAVGAFLNVMNNAILRSKL-REGEDPASYGITAFNHPLNLTKEQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHMQCISGVKPVIYWLANFVWDMCNYVVPATLVIIIFICFQQDSYVSSSNLPVLALLLLLYGWSITPLMYPASFIFKIPSTAYVVLTSVNLFIGINGSVATFVLELF--TNNKLSNINEILKSVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPMSWDLVGRNLFAMAV-------------EGVVFFAITLMIQYRFFIKPRPVNAKLPPVVDEDEDVARERQRIN-EGGRNDILELKGLTKIY 1852

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 315.849 bits (808), Expect = 1.145e-90
Identity = 262/866 (30.25%), Postives = 436/866 (50.35%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN-----------------AQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-------DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--CMNPSIYRSTHY---RCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLN------SLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF------NNKIKKT--EDFDISLEKNRMNSEQKFDDVLQVINLTKIY 2404
             DRIAIIS GKL C GSS+FLK + G GY L LVK  N                  ++++  +  S++G                +   I  H+P+A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VADD   ++ ET +  L P    R A +GD ++   PF + +       D++ ++     L  ++   +++L + + L++QQ   L  KR  YAKR++KG FA+++LP + + + +    +V P    P++E+ PW+   +       TF+  +        +  G +  +  L D+         G S ++  C       ST +        + N  W+      +   SP C+C++   +    IC  P +GG P   R   +SD L NLTG NISDYL+K + ++  K YGGF      + G S     +SP      + V  +  NH +  L       + +F+D      K    K +  ++W N+KG+ ++ A+ N+ +N +LRS+L +       YGI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERVS +K  Q +SG+ P +YW++NF+WD+  Y++P  ++IIIFI F   SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   T+      NEILK V LIFP + LGRG+ID+  N    +  + + +        W++    L ++ +              GV+   +  M++  +F      N K+     ED D++ E+ R+N E   +D+L++  LTKIY
Sbjct: 1097 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKRDNDSSLSSCRNSSSTMSYLKKEDSVSQSSSDAGLGSDHESDTMTIDVSAISNLINKHVPEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGIADTTLEEIFLKVADDTG-VDAETSDGTL-PARRKRYA-FGDHQSCLRPFTEDDAFDTNDSDMDPESRETDYLSGIDGKGSYQL-KSWNLMRQQFTALLWKRLLYAKRSRKGFFAQIVLPAVFVLIALVFSLIVPPFGKYPSLELEPWMYDEQY------TFFSND------APDDQGTQALLKALIDKPGFGTACMEGHSVMKVSCSGEEEEWSTQFVSQSVMDLFLNGNWT------MENPSPSCECSSDKRKKMLPIC-PPGAGGLPPFQRRQNTSDILQNLTGRNISDYLVKTYSQIIEKRYGGF------SLGAS-----NSPALPPNEEVV--ASINHIKKRLELPQNGAANRFLDSFGAFMKGLDTKDN-VKVWFNNKGWHAVGAFLNVMNNAILRSKL-REGEDPASYGITAFNHPLNLTKEQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHMQCISGVKPVIYWLANFVWDMCNYVVPATLVIIIFICFQQDSYVSSSNLPVLALLLLLYGWSITPLMYPASFIFKIPSTAYVVLTSVNLFIGINGSVATFVLELF--TNNKLSNINEILKSVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPMSWDLVGRNLFAMAV-------------EGVVFFAITLMIQYRFFIKPRPVNAKLPPVVDEDEDVARERQRIN-EGGRNDILELKGLTKIY 1908

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 315.079 bits (806), Expect = 2.162e-90
Identity = 254/863 (29.43%), Postives = 430/863 (49.83%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN-----------------AQKENFRKGISNSG-----------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-------DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--CMNPSIYRSTHY---RCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF------NNKIKKT--EDFDISLEKNRMNSEQKFDDVLQVINLTKIY 2404
             DRIAIIS GKL C GSS+FLK + G GY L LVK  N                  ++++  +  S++G                   +   I  H+P+A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VADD   ++ ET +  L P    R A +GD ++   PF + +       D++ ++     L  ++   +++L + + L++QQ   L  KR  YAKR++KG FA+++LP + + + +    +V P    P++E+ PW+   +       TF+  +        +  G +  +  L D+         G S ++  C       ST +        + N  W+      +   SP C+C++   +    IC  P +GG P   R   +SD L NLTG NISDYL+K + ++  K YGGF                           + AS +     N   +  I++++K  ++  ++  ++ +W N+KG+ ++ A+ N+ +N +LRS+L +       YGI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERVS +K  Q +SG+ P +YW++NF+WD+  Y++P  ++IIIFI F   SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++          TN ILK V LIFP + LGRG+ID+  N    +  + + +        W++    L ++ +              GV+   +  M++  +F      N K+     ED D++ E+ R+N E   +D+L++  LTKIY
Sbjct: 1067 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKRDNDSSLSSCRNSSSTMSYLKKEDSVSQSSSDAGLGSDHESDTMTIGLTDVSAISNLINKHVPEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGIADTTLEEIFLKVADDTG-VDAETSDGTL-PARRKRYA-FGDHQSCLRPFTEDDAFDTNDSDMDPESRETDYLSGIDGKGSYQL-KSWNLMRQQFTALLWKRLLYAKRSRKGFFAQIVLPAVFVLIALVFSLIVPPFGKYPSLELEPWMYDEQY------TFFSNDA------PDDQGTQALLKALIDKPGFGTACMEGHSVMKVSCSGEEEEWSTQFVSQSVMDLFLNGNWT------MENPSPSCECSSDKRKKMLPIC-PPGAGGLPPFQRRQNTSDILQNLTGRNISDYLVKTYSQIIEKRYGGFS--------------------------LGASNSPALPPNEEVVASINHIKKRLELPQVEYLYSVVWFNNKGWHAVGAFLNVMNNAILRSKL-REGEDPASYGITAFNHPLNLTKEQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHMQCISGVKPVIYWLANFVWDMCNYVVPATLVIIIFICFQQDSYVSSSNLPVLALLLLLYGWSITPLMYPASFIFKIPSTAYVVLTSVNLFIGINGSVATFVLELF---------TNNILKSVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPMSWDLVGRNLFAMAV-------------EGVVFFAITLMIQYRFFIKPRPVNAKLPPVVDEDEDVARERQRIN-EGGRNDILELKGLTKIY 1856

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Match: klf9 (Kruppel-like factor 9 [Source:Xenbase;Acc:XB-GENE-483889])

HSP 1 Score: 313.153 bits (801), Expect = 1.048e-89
Identity = 262/885 (29.60%), Postives = 426/885 (48.14%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISN-------------------------SGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISL-------NFN------RNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWS-PIPNGNIPLI-----------SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSR-----------KLYGGFQF--VLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLK-FIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVL-----YRMLKVSYFNNKIK---KTEDFDISLEKNRMNSEQKFDDVLQVINLTKIY 2404
             DRIAI+SQGKL C GS +FLK  FG G+ L LV+     K+  +K  ++                          GD   L + I  H+P+AK+      +  ++LP  D     ++ LF  L+E + +L   S+G+SDT LEE+F++V  D +    ET  E ++    +R ++   ++NQ   +++++  Q++ + K            N N      R  + ++G  LL+QQ   L IKRF +A R+ K  FA+++LP   + L +    +V P    P++ + PW+                  Q  F    Q GN+           + + +  G  G RCM      S  Y+C     +N+W+ P  + ++  +           SP C C++    +    C +   G PP   RI  SS+ + +LT  NISD+LLK +P L R           + YGG      LP        ++    F+ ++    N +     ++    L+ F+  L+    I        ++W N+KG+ SM  + N+ +N  +      +     ++GI+  N P+ + +       V    +++ +AI VIF +SFIPASFV++L++ERVS +K  QFVSG+ P +YW++NF WDI+ Y I + +++IIFIAFD ++Y  S N  A I LL FYG A+IP MYP S+  + PSTA+V L+  NL +G  ++  TFILD+ E+ + +    NE LK + LIFP + LGRG+IDL+ N     +TD YA++      + F WE     + ++ +              GV+   L     +R    ++F+   K   + ED D++ E+ R+      +D+L++  LTK Y
Sbjct: 1195 GDRIAIVSQGKLFCSGSPLFLKNCFGTGFYLTLVRRMRNIKDTGKKDSASCQSDCSCPCSSCTPKVKENLLEQELDGDVSGLTELIHHHVPEAKLLESIGQELIYLLPSKDFKFRAYASLFRELEETLGDLGLSSFGISDTPLEEIFLKVTAD-SVTGTETPEEWMLQQRKSRTSL--GVDNQTTVINIDNKGQESSIRKDSHHCKAEKNPPNINDREADGRGSRQIKGTELLQQQFNALIIKRFKHATRSHKDFFAQIVLPASFVLLALVFTLIVPPFGEYPSLTLHPWIY---------------GQQFVFFSNEQPGNEQMAT-----FSNAFLNSPG-LGTRCMKDQPL-SKKYQC--TNTSNEWTMPAVSPSVTNMLLSQEWTRDNPSPSCTCSSRSKLMMLPECPEGAGGRPPPQ-RIQPSSEIIQDLTERNISDFLLKTYPDLIRSSMKSKYWVNEQRYGGISVGGKLPVLHVKGGDIVS---FFSQVGQMTNVTAGTTTKAISQELQTFLQNLETEDNI--------KVWFNNKGWHSMVIFINV-ANNAILRANLGADKDPEEFGITTMNHPLNLTKDQLSEVTVLTTSVDVVVAICVIFAMSFIPASFVLYLIQERVSNAKHLQFVSGVTPAIYWLTNFAWDIINYAISVAMVVIIFIAFDKKAYTSSSNLPALIALLFFYGWAVIPMMYPASYLFNVPSTAYVALSCINLFIGINSSAITFILDLFEN-NRSLLKFNEKLKDLLLIFPHFCLGRGLIDLAMNQA---VTDVYARFGEEHVSNPFQWEFLGRNIFAMAV-------------EGVVYFTLNLLIQHRFFFSTWFSEPPKGLVEGEDEDVAQERQRVIKGGGKNDILKLKELTKTY 2022

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Match: ABCA1 (ATP binding cassette subfamily A member 1 [Source:NCBI gene;Acc:100491942])

HSP 1 Score: 311.612 bits (797), Expect = 2.701e-89
Identity = 257/864 (29.75%), Postives = 423/864 (48.96%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN-----------------AQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-------DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHY---RCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQF------VLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF------NNKIKKT--EDFDISLEKNRMNSEQKFDDVLQVINLTKIY 2404
             DRIAIIS GKL C GSS+FLK + G GY L LVK  N                  ++++  +  S++G                +   I  H+P+A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG++DT+LEE+F++VADD   ++ ET +  L P    R A +GD ++   PF + +       D++ ++     L  ++   +++L + + L++QQ   L  KR  YAKR++KG FA+++LP + + + +    +V P    P++E+ PW+   +       TF+  +        +  G +  +  L D+         G +   C       ST +        + N  W+      +   SP C+C++   +    IC  P +GG P   R   +SD L NLTG NISDYL+K + ++  K YGGF         LPS  G   K+ G          F+       N                           ++W N+KG+ ++ A+ N+ +N +LRS+L +       YGI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERVS +K  Q +SG+ P +YW++NF+WD+  Y++P  ++IIIFI F   SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   T+      NEILK V LIFP + LGRG+ID+  N    +  + + +        W++    L ++ +              GV+   +  M++  +F      N K+     ED D++ E+ R+N E   +D+L++  LTKIY
Sbjct: 1064 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKRDNDSSLSSCRNSSSTMSYLKKEDSVSQSSSDAGLGSDHESDTMTIDVSAISNLINKHVPEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGIADTTLEEIFLKVADDTG-VDAETSDGTL-PARRKRYA-FGDHQSCLRPFTEDDAFDTNDSDMDPESRETDYLSGIDGKGSYQL-KSWNLMRQQFTALLWKRLLYAKRSRKGFFAQIVLPAVFVLIALVFSLIVPPFGKYPSLELEPWMYDEQY------TFFSNDA------PDDQGTQALLKALIDK------PGFG-TAFSCSGEEEEWSTQFVSQSVMDLFLNGNWT------MENPSPSCECSSDKRKKMLPIC-PPGAGGLPPFQRRQNTSDILQNLTGRNISDYLVKTYSQIIEKRYGGFSLGASNSPALPSVVGKLLKIFGA---------FMKGLDTKDN--------------------------VKVWFNNKGWHAVGAFLNVMNNAILRSKL-REGEDPASYGITAFNHPLNLTKEQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHMQCISGVKPVIYWLANFVWDMCNYVVPATLVIIIFICFQQDSYVSSSNLPVLALLLLLYGWSITPLMYPASFIFKIPSTAYVVLTSVNLFIGINGSVATFVLELF--TNNKLSNINEILKSVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPMSWDLVGRNLFAMAV-------------EGVVFFAITLMIQYRFFIKPRPVNAKLPPVVDEDEDVARERQRIN-EGGRNDILELKGLTKIY 1845

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
Match: Abca1 (ATP-binding cassette, sub-family A (ABC1), member 1 [Source:MGI Symbol;Acc:MGI:99607])

HSP 1 Score: 296.59 bits (758), Expect = 3.071e-84
Identity = 257/879 (29.24%), Postives = 438/879 (49.83%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIP--------NGNIPL--ISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWS-SKLIGDSPFWEELRDFVNASQANHNQSNLNSL-KFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF--NNKIKKT------EDFDISLEKNRMNSEQKFDDVLQVINLTKIYNR 2410
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 +   ++++  +  S++G                +   I+ H+ +A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG+S+T+LEE+F++VA++ + ++ ET +  L P   NR A +GD ++   PF   D  D N      +S    L+S    +    L+G+ L +QQ + L  KR   A+R++KG FA+++LP + + + +    +V P    P++E+ PW+            +  +   ++      +G +  +N LT         D G  G RCM  +    T   C    ++   SP+P        NGN  +   SP C C++   +    +C     G P    R   ++D L NLTG NISDYL+K + ++  K            YGGF   + ++     S  + D+   ++++  +  ++ +     L+SL +F+  L     +        ++W N+KG+ ++ ++ N+ +N +LR+ L K       YGI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERVS +K  QF+SG+ P +YW+SNF+WD+  Y++P  ++IIIFI F  +SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   T+      N+ILK VFLIFP + LGRG+ID+  N    +  + + +        W++    L ++ +              GV+  ++  +++  +F     +K        ED D+  E+ R+      +D+L++  LTKIY R
Sbjct: 1098 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSCLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEE-SGVDAETSDGTL-PARRNRRA-FGDKQSCLHPFTEDDAVDPNDSDIDPESRETDLLSGMDGKGSYQLKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWM------------YNEQYTFVSNDAPEDMGTQELLNALT--------KDPG-FGTRCMEGNPIPDTP--CLAGEEDWTISPVPQSIVDLFQNGNWTMKNPSPACQCSSDKIKKMLPVCPPGAGGLP-PPQRKQKTADILQNLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNSQALPPSHEVNDAI--KQMKKLLKLTKDSSADRFLSSLGRFMAGLDTKNNV--------KVWFNNKGWHAISSFLNVINNAILRANLQKGE-NPSQYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELF--TNNKLNDINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAV-------------EGVVFFLITVLIQYRFFIRPRPVKAKLPPLNDEDEDVRRERQRILDGGGQNDILEIKELTKIYRR 1923

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
Match: Abca4 (ATP-binding cassette, sub-family A (ABC1), member 4 [Source:MGI Symbol;Acc:MGI:109424])

HSP 1 Score: 295.819 bits (756), Expect = 5.904e-84
Identity = 248/886 (27.99%), Postives = 421/886 (47.52%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILV---KNFNAQKENFR-------KGISN---------------SGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPA----------KINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--------CMNPSIYRS-------THYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSR-----------KLYGGFQF--VLPSTFGWSSKLIGDSPFWEELRDFVNASQAN-HNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKT--------EDFDISLEKNRMNSEQKFDDVLQVINLTKIYN 2407
             DRIAIISQG+L C G+ +FLK  FG G+ L LV   KN  +Q+           KG S                 GD  +L+  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D            +  E+            ++  Y    +      ++    Q   +     + FN   +L+       Q +  L +KRFH+  R++K   A+++LP   + L + L  +V P    PA+ + PW+                 +Q  F   ++  N++ +  L D L +  R   G   ++        C+N + +++       TH      ++  KW+          SP C C+T    T    C +  +GG P   R   S++ L +LT  NISDYL+K +P L R           + YGG      LP+       L+G   F   L   +N S      +++   L F+ +L+ T  I        ++W N+KG+ ++ ++ N+  N +LR+ L +      +YGI+V + P+ + +       V    ++  +AI VIF +SF+PASFV++L++ERV+ +K  QF+SG++P  YW++NFLWDIM Y +   +++ IFI F  ++Y    N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TF+L++ E+     R  N +L+K+ ++FP + LGRG+IDL+   +   +TD YA++      + F W++  + L ++ +              GV+  +L  +++  +F  +            ED D++ E+ R+ S     D+L++  LTK+Y+
Sbjct: 1127 GDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGVCSCTSKGFSTRCPTRVDEITEEQVLDGDVQELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDAGAGSMFVGGAQQKREQAGLRHPCSAPTEKLRQYAQAPHTCSPGQVDPPKGQPSPEPEDPGVPFNTGARLIL------QHVQALLVKRFHHTIRSRKDFVAQIVLPATFVFLALMLSIIVPPFGEFPALTLHPWMY---------------GHQYTFFSMDEPNNEH-LEVLADVLLN--RPGFGNRCLKEEWLPEYPCINATSWKTPSVSPNITHL-----FQKQKWTAAHP------SPSCKCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPAIPISGEALVG---FLSGLGQMMNVSGGPVTREASKEMLDFLKHLETTDNI--------KVWFNNKGWHALVSFLNVAHNAILRASLPRDRDP-EEYGITVISQPLNLTKEQLSDITVLTTSVDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIMNYAVSAGLVVGIFIGFQKKAYTSPDNLPALVSLLMLYGWAVIPMMYPASFLFEVPSTAYVALSCANLFIGINSSAITFVLELFENNRTLLR-FNAMLRKLLIVFPHFCLGRGLIDLA---LSQAVTDVYAQFGEEYSANPFQWDLIGKNLVAMAI-------------EGVVYFLLTLLIQHHFFLTRWIAEPAREPVFDEDDDVAEERQRVMSGGNKTDILKLNELTKVYS 1947

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
Match: Abca7 (ATP-binding cassette, sub-family A (ABC1), member 7 [Source:MGI Symbol;Acc:MGI:1351646])

HSP 1 Score: 272.707 bits (696), Expect = 2.613e-76
Identity = 249/890 (27.98%), Postives = 422/890 (47.42%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------------NFNAQKENFRKGISN---------------SGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIY-------RSTH----YRCFPEYKNNKWSPIPNGN-IP-LISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFV-----LPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFT-RIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVL----YRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFN 2419
             DR+A+++ G L CCGS +FL+R  G GY L LVK                         N       F +G S+               S  ++L+ ++ H+P A++  +   +   VLP   +    F+ +F  LD++++ L    YG+SDT+LEE+F++V +D  +   +++ +     +L           +   L+  +L  Q              N   ++G+ L  QQ+  L  KRF  A+R+++G+FA+++LP L + L +    +V P    P +++SP +  P               Q++F   +  G+ N +  L         + LGE+G++   PS+          TH    Y   PE   +  S + +GN  P   SP C C+  G +     C     G P     +    + + NLTG N+SD+L+K +P L R+            YGGF        LP+       L        E+R  ++    N     LN+L        T    G+    + +IW N+KG+ +M A+ N  +N LL + L    V+   + I+  N P+ + +       +    +++ ++I V+F +SF+PASF + L+EER++ +K  Q VSG+   +YW+ NFLWD+  Y++ + I++ IF+AF  ++Y+  +N  A +LLL+ YG +I P MYP SFF S PSTA+VVL   NL +G  ++M+TF+L+++  +D+  +  + ILK+VFLIFP + LGRG+ID+  N     M D + +           W++  + L +++    L+ +I ++++    NR+L     R+L            ED D++ E+ R+       DVL + +LTK+Y    N
Sbjct: 1002 GDRVAMVAGGSLCCCGSPLFLRRHLGCGYYLTLVKSSQSLVTHDAKGDSEDPRREKKSDGNGRTSDTAFTRGTSDKSNQAPAPGAVPITPSTARILELVQQHVPGAQLVEDLPHELLLVLPYAGALDGSFAMVFQELDQQLELLGLTGYGISDTNLEEIFLKVVEDAHREGGDSRPQL----HLRTCTPQPPTGPEASVLENGELAPQGLAP----------NAAQVQGWTLTCQQLRALLHKRFLLARRSRRGLFAQVVLPALFVGLALFFSLIVPPFGQYPPLQLSPAMYGP---------------QVSFFSEDAPGDPNRMKLL--------EALLGEAGLQ--EPSMQDKDARGSECTHSLACYFTVPEVPPDVASILASGNWTPESPSPACQCSQPGARRLLPDCPAGAGGPP-PPQAVAGLGEVVQNLTGRNVSDFLVKTYPSLVRRGLKTKKWVDEVRYGGFSLGGRDPDLPTGHEVVRTL-------AEIRALLSPQPGNALDRILNNL--------TQWALGLDARNSLKIWFNNKGWHAMVAFVNRANNGLLHALLPSGPVRHA-HSITTLNHPLNLTKEQLSEATLIASSVDVLVSICVVFAMSFVPASFTLVLIEERITRAKHLQLVSGLPQTLYWLGNFLWDMCNYLVAVCIVVFIFLAFQQRAYVAPENLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELL--SDQNLQEVSRILKQVFLIFPHFCLGRGLIDMVRN---QAMADAFERLGDKQFQSPLRWDIIGKNLLAMMAQGPLFLLITLLLQH--RNRLLPQSKPRLLPP-------LGEEDEDVAQERERVTKGATQGDVLVLRDLTKVYRGQRN 1821

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Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------------NFNAQKENFRKGISN---------------SGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIY-------RSTH----YRCFPEYKNNKWSPIPNGN-IP-LISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFV-----LPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFT-RIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVL----YRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFN 2419
             DR+A+++ G L CCGS +FL+R  G GY L LVK                         N       F +G S+               S  ++L+ ++ H+P A++  +   +   VLP   +    F+ +F  LD++++ L    YG+SDT+LEE+F++V +D  +   +++ +     +L           +   L+  +L  Q              N   ++G+ L  QQ+  L  KRF  A+R+++G+FA+++LP L + L +    +V P    P +++SP +  P               Q++F   +  G+ N +  L         + LGE+G++   PS+          TH    Y   PE   +  S + +GN  P   SP C C+  G +     C     G P     +    + + NLTG N+SD+L+K +P L R+            YGGF        LP+       L        E+R  ++    N     LN+L        T    G+    + +IW N+KG+ +M A+ N  +N LL + L    V+   + I+  N P+ + +       +    +++ ++I V+F +SF+PASF + L+EER++ +K  Q VSG+   +YW+ NFLWD+  Y++ + I++ IF+AF  ++Y+  +N  A +LLL+ YG +I P MYP SFF S PSTA+VVL   NL +G  ++M+TF+L+++  +D+  +  + ILK+VFLIFP + LGRG+ID+  N     M D + +           W++  + L +++    L+ +I ++++    NR+L     R+L            ED D++ E+ R+       DVL + +LTK+Y    N
Sbjct: 1002 GDRVAMVAGGSLCCCGSPLFLRRHLGCGYYLTLVKSSQSLVTHDAKGDSEDPRREKKSDGNGRTSDTAFTRGTSDKSNQAPAPGAVPITPSTARILELVQQHVPGAQLVEDLPHELLLVLPYAGALDGSFAMVFQELDQQLELLGLTGYGISDTNLEEIFLKVVEDAHREGGDSRPQL----HLRTCTPQPPTGPEASVLENGELAPQGLAP----------NAAQVQGWTLTCQQLRALLHKRFLLARRSRRGLFAQVVLPALFVGLALFFSLIVPPFGQYPPLQLSPAMYGP---------------QVSFFSEDAPGDPNRMKLL--------EALLGEAGLQ--EPSMQDKDARGSECTHSLACYFTVPEVPPDVASILASGNWTPESPSPACQCSQPGARRLLPDCPAGAGGPP-PPQAVAGLGEVVQNLTGRNVSDFLVKTYPSLVRRGLKTKKWVDEVRYGGFSLGGRDPDLPTGHEVVRTL-------AEIRALLSPQPGNALDRILNNL--------TQWALGLDARNSLKIWFNNKGWHAMVAFVNRANNGLLHALLPSGPVRHA-HSITTLNHPLNLTKEQLSEATLIASSVDVLVSICVVFAMSFVPASFTLVLIEERITRAKHLQLVSGLPQTLYWLGNFLWDMCNYLVAVCIVVFIFLAFQQRAYVAPENLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELL--SDQNLQEVSRILKQVFLIFPHFCLGRGLIDMVRN---QAMADAFERLGDKQFQSPLRWDIIGKNLLAMMAQGPLFLLITLLLQH--RNRLLPQSKPRLLPP-------LGEEDEDVAQERERVTKGATQGDVLVLRDLTKVYRGQRN 1821

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
Match: Abca7 (ATP-binding cassette, sub-family A (ABC1), member 7 [Source:MGI Symbol;Acc:MGI:1351646])

HSP 1 Score: 271.937 bits (694), Expect = 5.009e-76
Identity = 251/890 (28.20%), Postives = 421/890 (47.30%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------------NFNAQKENFRKGISN---------------SGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIY-------RSTH----YRCFPEYKNNKWSPIPNGN-IP-LISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFV-----LPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFT-RIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVL----YRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFN 2419
             DR+A+++ G L CCGS +FL+R  G GY L LVK                         N       F +G S+               S  ++L+ ++ H+P A++  +   +   VLP   +    F+ +F  LD++++ L    YG+SDT+LEE+F++V +D  +   +++     P    R          E  + LE+      V           N   ++G+ L  QQ+  L  KRF  A+R+++G+FA+++LP L + L +    +V P    P +++SP +  P               Q++F   +  G+ N +  L         + LGE+G++   PS+          TH    Y   PE   +  S + +GN  P   SP C C+  G +     C     G P     +    + + NLTG N+SD+L+K +P L R+            YGGF        LP+       L        E+R  ++    N     LN+L        T    G+    + +IW N+KG+ +M A+ N  +N LL + L    V+   + I+  N P+ + +       +    +++ ++I V+F +SF+PASF + L+EER++ +K  Q VSG+   +YW+ NFLWD+  Y++ + I++ IF+AF  ++Y+  +N  A +LLL+ YG +I P MYP SFF S PSTA+VVL   NL +G  ++M+TF+L+++  +D+  +  + ILK+VFLIFP + LGRG+ID+  N     M D + +           W++  + L +++    L+ +I ++++    NR+L     R+L            ED D++ E+ R+       DVL + +LTK+Y    N
Sbjct: 1002 GDRVAMVAGGSLCCCGSPLFLRRHLGCGYYLTLVKSSQSLVTHDAKGDSEDPRREKKSDGNGRTSDTAFTRGTSDKSNQAPAPGAVPITPSTARILELVQQHVPGAQLVEDLPHELLLVLPYAGALDGSFAMVFQELDQQLELLGLTGYGISDTNLEEIFLKVVEDAHREGGDSR-----PQLHLRTCTPQPPTGPEASV-LENGELAKLVLDPQAPQGLAPNAAQVQGWTLTCQQLRALLHKRFLLARRSRRGLFAQVVLPALFVGLALFFSLIVPPFGQYPPLQLSPAMYGP---------------QVSFFSEDAPGDPNRMKLL--------EALLGEAGLQ--EPSMQDKDARGSECTHSLACYFTVPEVPPDVASILASGNWTPESPSPACQCSQPGARRLLPDCPAGAGGPP-PPQAVAGLGEVVQNLTGRNVSDFLVKTYPSLVRRGLKTKKWVDEVRYGGFSLGGRDPDLPTGHEVVRTL-------AEIRALLSPQPGNALDRILNNL--------TQWALGLDARNSLKIWFNNKGWHAMVAFVNRANNGLLHALLPSGPVRHA-HSITTLNHPLNLTKEQLSEATLIASSVDVLVSICVVFAMSFVPASFTLVLIEERITRAKHLQLVSGLPQTLYWLGNFLWDMCNYLVAVCIVVFIFLAFQQRAYVAPENLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELL--SDQNLQEVSRILKQVFLIFPHFCLGRGLIDMVRN---QAMADAFERLGDKQFQSPLRWDIIGKNLLAMMAQGPLFLLITLLLQH--RNRLLPQSKPRLLPP-------LGEEDEDVAQERERVTKGATQGDVLVLRDLTKVYRGQRN 1829

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BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Match: sp|O95477|ABCA1_HUMAN (Phospholipid-transporting ATPase ABCA1 OS=Homo sapiens OX=9606 GN=ABCA1 PE=1 SV=3)

HSP 1 Score: 298.13 bits (762), Expect = 6.509e-84
Identity = 259/881 (29.40%), Postives = 440/881 (49.94%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKW--SPIP--------NGNIPL--ISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWS-SKLIGDSPFWEELRDFVNASQANHNQSNLNSL-KFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF------NNKIKKT--EDFDISLEKNRMNSEQKFDDVLQVINLTKIYNR 2410
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 ++  ++++  +  S++G                +   I+ H+ +A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG+S+T+LEE+F++VA++ + ++ ET +  L P   NR A +GD ++   PF   D  D N      +S    L+S    +    ++G+ L +QQ + L  KR   A+R++KG FA+++LP + + + +    +V P    P++E+ PW+            +  +   ++       G    +N LT         D G  G RCM  +    T  +   E    +W  +P+P        NGN  +   SP C C++   +    +C     G P    R   ++D L +LTG NISDYL+K + ++  K            YGGF   + +T     S+ + D+   ++++  +  ++ +     LNSL +F+  L     +        ++W N+KG+ ++ ++ N+ +N +LR+ L K       YGI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERVS +K  QF+SG+ P +YW+SNF+WD+  Y++P  ++IIIFI F  +SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   TD      N+ILK VFLIFP + LGRG+ID+  N    +  + + +        W++    L ++ +              GV+  ++  +++  +F      N K+     ED D+  E+ R+      +D+L++  LTKIY R
Sbjct: 1098 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSYLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEE-SGVDAETSDGTL-PARRNRRA-FGDKQSCLRPFTEDDAADPNDSDIDPESRETDLLSGMDGKGSYQVKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWM------------YNEQYTFVSNDAPEDTGTLELLNALT--------KDPG-FGTRCMEGNPIPDTPCQAGEE----EWTTAPVPQTIMDLFQNGNWTMQNPSPACQCSSDKIKKMLPVCPPGAGGLP-PPQRKQNTADILQDLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNTQALPPSQEVNDAI--KQMKKHLKLAKDSSADRFLNSLGRFMTGLDTKNNV--------KVWFNNKGWHAISSFLNVINNAILRANLQKGE-NPSHYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELF--TDNKLNNINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAV-------------EGVVFFLITVLIQYRFFIRPRPVNAKLSPLNDEDEDVRRERQRILDGGGQNDILEIKELTKIYRR 1923

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BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Match: sp|P41233|ABCA1_MOUSE (Phospholipid-transporting ATPase ABCA1 OS=Mus musculus OX=10090 GN=Abca1 PE=1 SV=4)

HSP 1 Score: 296.59 bits (758), Expect = 2.148e-83
Identity = 257/879 (29.24%), Postives = 438/879 (49.83%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQKENFRKGISNSG--------------DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFL--DLEDLNQQAFVDKS----LISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIP--------NGNIPL--ISPECDCNTTGYQ----ICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWS-SKLIGDSPFWEELRDFVNASQANHNQSNLNSL-KFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF--NNKIKKT------EDFDISLEKNRMNSEQKFDDVLQVINLTKIYNR 2410
             DRIAIIS GKL C GSS+FLK + G GY L LVK                 +   ++++  +  S++G                +   I+ H+ +A++  +   + ++VLP   +    F  LF  +D+ + +L   SYG+S+T+LEE+F++VA++ + ++ ET +  L P   NR A +GD ++   PF   D  D N      +S    L+S    +    L+G+ L +QQ + L  KR   A+R++KG FA+++LP + + + +    +V P    P++E+ PW+            +  +   ++      +G +  +N LT         D G  G RCM  +    T   C    ++   SP+P        NGN  +   SP C C++   +    +C     G P    R   ++D L NLTG NISDYL+K + ++  K            YGGF   + ++     S  + D+   ++++  +  ++ +     L+SL +F+  L     +        ++W N+KG+ ++ ++ N+ +N +LR+ L K       YGI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERVS +K  QF+SG+ P +YW+SNF+WD+  Y++P  ++IIIFI F  +SY+ S N     LLL+ YG +I P MYP SF    PSTA+VVL + NL +G   +++TF+L++   T+      N+ILK VFLIFP + LGRG+ID+  N    +  + + +        W++    L ++ +              GV+  ++  +++  +F     +K        ED D+  E+ R+      +D+L++  LTKIY R
Sbjct: 1098 GDRIAIISHGKLCCVGSSLFLKNQLGTGYYLTLVKKDVESSLSSCRNSSSTVSCLKKEDSVSQSSSDAGLGSDHESDTLTIDVSAISNLIRKHVSEARLVEDIGHELTYVLPYEAAKEGAFVELFHEIDDRLSDLGISSYGISETTLEEIFLKVAEE-SGVDAETSDGTL-PARRNRRA-FGDKQSCLHPFTEDDAVDPNDSDIDPESRETDLLSGMDGKGSYQLKGWKLTQQQFVALLWKRLLIARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWM------------YNEQYTFVSNDAPEDMGTQELLNALT--------KDPG-FGTRCMEGNPIPDTP--CLAGEEDWTISPVPQSIVDLFQNGNWTMKNPSPACQCSSDKIKKMLPVCPPGAGGLP-PPQRKQKTADILQNLTGRNISDYLVKTYVQIIAKSLKNKIWVNEFRYGGFSLGVSNSQALPPSHEVNDAI--KQMKKLLKLTKDSSADRFLSSLGRFMAGLDTKNNV--------KVWFNNKGWHAISSFLNVINNAILRANLQKGE-NPSQYGITAFNHPLNLTKQQLSEVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVSKAKHLQFISGVKPVIYWLSNFVWDMCNYVVPATLVIIIFICFQQKSYVSSTNLPVLALLLLLYGWSITPLMYPASFVFKIPSTAYVVLTSVNLFIGINGSVATFVLELF--TNNKLNDINDILKSVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFVSPLSWDLVGRNLFAMAV-------------EGVVFFLITVLIQYRFFIRPRPVKAKLPPLNDEDEDVRRERQRILDGGGQNDILEIKELTKIYRR 1923

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BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Match: sp|O35600|ABCA4_MOUSE (Retinal-specific phospholipid-transporting ATPase ABCA4 OS=Mus musculus OX=10090 GN=Abca4 PE=2 SV=1)

HSP 1 Score: 295.819 bits (756), Expect = 4.130e-83
Identity = 248/886 (27.99%), Postives = 421/886 (47.52%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILV---KNFNAQKENFR-------KGISN---------------SGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPA----------KINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIR--------CMNPSIYRS-------THYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSR-----------KLYGGFQF--VLPSTFGWSSKLIGDSPFWEELRDFVNASQAN-HNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKT--------EDFDISLEKNRMNSEQKFDDVLQVINLTKIYN 2407
             DRIAIISQG+L C G+ +FLK  FG G+ L LV   KN  +Q+           KG S                 GD  +L+  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D            +  E+            ++  Y    +      ++    Q   +     + FN   +L+       Q +  L +KRFH+  R++K   A+++LP   + L + L  +V P    PA+ + PW+                 +Q  F   ++  N++ +  L D L +  R   G   ++        C+N + +++       TH      ++  KW+          SP C C+T    T    C +  +GG P   R   S++ L +LT  NISDYL+K +P L R           + YGG      LP+       L+G   F   L   +N S      +++   L F+ +L+ T  I        ++W N+KG+ ++ ++ N+  N +LR+ L +      +YGI+V + P+ + +       V    ++  +AI VIF +SF+PASFV++L++ERV+ +K  QF+SG++P  YW++NFLWDIM Y +   +++ IFI F  ++Y    N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TF+L++ E+     R  N +L+K+ ++FP + LGRG+IDL+   +   +TD YA++      + F W++  + L ++ +              GV+  +L  +++  +F  +            ED D++ E+ R+ S     D+L++  LTK+Y+
Sbjct: 1127 GDRIAIISQGRLYCSGTPLFLKNCFGTGFYLTLVRKMKNIQSQRGGCEGVCSCTSKGFSTRCPTRVDEITEEQVLDGDVQELMDLVYHHVPEAKLVECIGQELIFLLPNKNFKQRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDAGAGSMFVGGAQQKREQAGLRHPCSAPTEKLRQYAQAPHTCSPGQVDPPKGQPSPEPEDPGVPFNTGARLIL------QHVQALLVKRFHHTIRSRKDFVAQIVLPATFVFLALMLSIIVPPFGEFPALTLHPWMY---------------GHQYTFFSMDEPNNEH-LEVLADVLLN--RPGFGNRCLKEEWLPEYPCINATSWKTPSVSPNITHL-----FQKQKWTAAHP------SPSCKCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEVLQDLTNRNISDYLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPAIPISGEALVG---FLSGLGQMMNVSGGPVTREASKEMLDFLKHLETTDNI--------KVWFNNKGWHALVSFLNVAHNAILRASLPRDRDP-EEYGITVISQPLNLTKEQLSDITVLTTSVDAVVAICVIFAMSFVPASFVLYLIQERVTKAKHLQFISGVSPTTYWLTNFLWDIMNYAVSAGLVVGIFIGFQKKAYTSPDNLPALVSLLMLYGWAVIPMMYPASFLFEVPSTAYVALSCANLFIGINSSAITFVLELFENNRTLLR-FNAMLRKLLIVFPHFCLGRGLIDLA---LSQAVTDVYAQFGEEYSANPFQWDLIGKNLVAMAI-------------EGVVYFLLTLLIQHHFFLTRWIAEPAREPVFDEDDDVAEERQRVMSGGNKTDILKLNELTKVYS 1947

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BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Match: sp|Q8IZY2|ABCA7_HUMAN (Phospholipid-transporting ATPase ABCA7 OS=Homo sapiens OX=9606 GN=ABCA7 PE=1 SV=3)

HSP 1 Score: 286.96 bits (733), Expect = 3.112e-80
Identity = 250/857 (29.17%), Postives = 412/857 (48.07%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------NFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAK---INEETKNEKL--------IPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGN-IP-LISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWSSKLIGDS--PFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYN 2407
             DR+A+++ G+L CCGS +FL+R  G GY L LVK                   +   +K+N  +G      +LL  ++  +P A++  E   +   VLP   ++   F+ LF  LD  +  L    YG+SDTSLEE+F++V ++ A    + + +  + L        +   L        +EN EP     + +Q +  D         R    ++G+ L +QQ+  L +KRF  A+R+++G+FA+++LP L + L +    +V P    PA+ +SP             T Y    Q++F   +  G+      L   L+        E+G+    P +  S+H    PE        + +GN  P   SP C C+  G +     C     G P     +  S + + NLTG N+SD+L+K +P+L R+            YGGF          S + +G S    W  L      +  +    NL +       Q + KI          W N+KG+ SM A+ N  SN +LR+ L     +   + I+  N P+ + +       +    +++ ++I V+F +SF+PASF + L+EERV+ +K  Q + G++P +YW+ NFLWD+  Y++P  I+++IF+AF  ++Y+   N  A +LLL+ YG +I P MYP SFF S PSTA+VVL   NL +G   +M+TF+L++   +D+  +  + ILK+VFLIFP + LGRG+ID+  N     M D + +           WEV  + L ++++   L+ +  ++++       L    +V      +   ED D++ E+ R+       DVL + NLTK+Y 
Sbjct: 1005 GDRVAVVAGGRLCCCGSPLFLRRHLGSGYYLTLVKARLPLTTNEKADTDMEGSVDTRQEKKNGSQGSRVGTPQLLALVQHWVPGARLVEELPHELVLVLPYTGAHDGSFATLFRELDTRLAELRLTGYGISDTSLEEIFLKVVEECAADTDMEDGSCGQHLCTGIAGLDVTLRLKMPPQETALENGEPAGSAPETDQGSGPDA------VGR----VQGWALTRQQLQALLLKRFLLARRSRRGLFAQIVLPALFVGLALVFSLIVPPFGHYPALRLSP-------------TMYGA--QVSFFSEDAPGDPGRARLLEALLQ--------EAGLE--EPPVQHSSHRFSAPEVPAEVAKVLASGNWTPESPSPACQCSRPGARRLLPDCPAAAGGPP-PPQAVTGSGEVVQNLTGRNLSDFLVKTYPRLVRQGLKTKKWVNEVRYGGFSLGGRDPGLPSGQELGRSVEELWALLSPLPGGA-LDRVLKNLTAWAHSLDAQDSLKI----------WFNNKGWHSMVAFVNRASNAILRAHLPPGPARHA-HSITTLNHPLNLTKEQLSEGALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLMGGLSPTLYWLGNFLWDMCNYLVPACIVVLIFLAFQQRAYVAPANLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINGSMATFVLELF--SDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRN---QAMADAFERLGDRQFQSPLRWEVVGKNLLAMVIQGPLFLLFTLLLQH---RSQLLPQPRVRSL--PLLGEEDEDVARERERVVQGATQGDVLVLRNLTKVYR 1803

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BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Match: sp|P78363|ABCA4_HUMAN (Retinal-specific phospholipid-transporting ATPase ABCA4 OS=Homo sapiens OX=9606 GN=ABCA4 PE=1 SV=3)

HSP 1 Score: 278.87 bits (712), Expect = 1.731e-77
Identity = 253/885 (28.59%), Postives = 424/885 (47.91%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILV---KNFNAQKENFR-------KGISNS---------------GD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHK--------------LLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKE-NQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYR--STHYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSR-----------KLYGGFQF-----VLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLK-FIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEM--EQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKT--------EDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRT 2413
             DRIAII+QG+L C G+ +FLK  FG G  L LV   KN  +Q++          KG S +               GD  +L+  +  H+P+AK+      +  F+LP  +     ++ LF  L+E + +L   S+G+SDT LEE+F++V +D           +   +N+N          + P L   +   Q   D ++ S      H               L  G  L+ Q +  L +KRF +  R+ K   A+++LP   + L + L  ++ P    PA+ + PW+   +    +++    ++   L   + N+ G  N    L +    EY          C N + ++  S        ++  KW+ +        SP C C+T    T    C +  +GG P   R   S++ L +LT  NISD+L+K +P L R           + YGG        V+P T      L+G   F  +L   +N S     +     +  F+ +L+    I        ++W N+KG+ ++ ++ N+  N +LR+ L K      +YGI+V + P+ +  EQ ++   L   +  +  +AI VIF +SF+PASFV++L++ERV+ SK  QF+SG++P  YWV+NFLWDIM Y +   +++ IFI F  ++Y   +N  A + LL+ YG A+IP MYP SF    PSTA+V L+  NL +G  ++  TFIL++ E+     R  N +L+K+ ++FP + LGRG+IDL+   +   +TD YA++      + F W++  + L ++++              GV+  +L  +++  +F ++            ED D++ E+ R+ +     D+L++  LTKIY  T
Sbjct: 1127 GDRIAIIAQGRLYCSGTPLFLKNCFGTGLYLTLVRKMKNIQSQRKGSEGTCSCSSKGFSTTCPAHVDDLTPEQVLDGDVNELMDVVLHHVPEAKLVECIGQELIFLLPNKNFKHRAYASLFRELEETLADLGLSSFGISDTPLEEIFLKVTEDSDSGPLFAGGAQQKRENVN---------PRHPCLGPREKAGQTPQDSNVCSPGAPAAHPEGQPPPEPECPGPQLNTGTQLVLQHVQALLVKRFQHTIRSHKDFLAQIVLPATFVFLALMLSIVIPPFGEYPALTLHPWIYGQQYTFFSMDEPGSEQFTVLADVLLNKPGFGNRC--LKEGWLPEYP---------CGNSTPWKTPSVSPNITQLFQKQKWTQVNP------SPSCRCSTREKLTMLPECPE-GAGGLPPPQRTQRSTEILQDLTDRNISDFLVKTYPALIRSSLKSKFWVNEQRYGGISIGGKLPVVPIT---GEALVG---FLSDLGRIMNVSGGPITREASKEIPDFLKHLETEDNI--------KVWFNNKGWHALVSFLNVAHNAILRASLPKDRSPE-EYGITVISQPLNLTKEQLSEITVLTTSV--DAVVAICVIFSMSFVPASFVLYLIQERVNKSKHLQFISGVSPTTYWVTNFLWDIMNYSVSAGLVVGIFIGFQKKAYTSPENLPALVALLLLYGWAVIPMMYPASFLFDVPSTAYVALSCANLFIGINSSAITFILELFENNRTLLR-FNAVLRKLLIVFPHFCLGRGLIDLA---LSQAVTDVYARFGEEHSANPFHWDLIGKNLFAMVV-------------EGVVYFLLTLLVQRHFFLSQWIAEPTKEPIVDEDDDVAEERQRIITGGNKTDILRLHELTKIYPGT 1950

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BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Match: A0A1S3JVH4 (LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 1-like OS=Lingula unguis OX=7574 GN=LOC106176500 PE=4 SV=2)

HSP 1 Score: 412.149 bits (1058), Expect = 1.712e-120
Identity = 297/926 (32.07%), Postives = 468/926 (50.54%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-------------------------NFNAQKENFRKGISNSGDK----------------------------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPA--KINEETKNEKL--------IPDNLNRIAVYGD----IENQEPFLDLEDLNQQAFVD----KSLISLNFNR---------NHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRS-INLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIP--NGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLI--GDSPFWEELRDFVNASQANHNQSNLNS----LKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTD----GYAKYDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLCF 2500
             DRIAIIS GKL+CCGSS+FLK K+G GY L +VK                          F ++K+     +S++G K                            +  F++  IP AK+  +  T+  F LP+  +++  F  LF  L+  +  L   SYG+SDT+LEEVF++VA++     +NEE     L        I   + R++         +  +P L++ D N+    D     S+ S+  +          +HK+  G    K Q + L +KRFH+ +R+ KG   E++LP + + + +   K++  ++  PA+E+ PW+ +P + +  +L  FY               N    + L D LE + RS LG  G RCMN S+Y    Y C P     +W+P P   GN  L SP C C+T GYQ C  P +GGP  S R+M ++D+L N+TG N+SD+L+K      ++ YGG+      + G  ++L+    S  ++ +     A   N+ Q  LN        ID L K   +     +  ++W N+KG+ +M +Y N  +N++LRS+L         YGI+VSN P+         D +N   + + +AI VIF +SFIPASFV++L+EERVS SK  QFVSG+N   YWVS+  WDIM Y + +++ I++F+AF+ +SY+   NA   +LLL  YG A+IP M+PF++    PSTAFV L   N+ +G  +T+ST++L+   D D+     N +L++VFLI P Y LGRG+ID+++N +  ++      G A  D F+W+     L +L +    W+   +     +I    +   ++S   N +   ED D++ E+ R  S +   D+L+V NLTK++++                  + +  AV+ LCF
Sbjct:  796 GDRIAIISLGKLRCCGSSLFLKNKYGSGYYLTMVKANSDEKPADRPVTALSNRTVSDIKAQFVSEKDEGVADMSDTGSKSEHSDSDQSATPPPEYEDPVPCVKDSSDVAVFVQKFIPSAKLVEDMGTELCFQLPEEGTHTGAFEALFRALESNLTKLGITSYGISDTTLEEVFLKVAEESGVDDVNEEQTRNALERYTEGGKIARPVTRLSFRKKKLDFFKKSKPVLNISDTNELVDSDFEDADSVASMPVSEVSTAQGGAGSHKV-TGLAHTKDQFLALFVKRFHHVRRSYKGFVCEILLPAIFVCIAMIFTKIIPVIKENPALELQPWMYVPITGTNPHLTVFYT--------------NDAPGSMLADSLERQIRSPLG-IGTRCMNSSVYSIRGYPCTPASSAERWTPSPAVTGNTSLDSPSCSCDT-GYQTC-PPGAGGPLGSSRVMDNTDRLVNMTGRNVSDWLVKTMEDYKKRRYGGY------SLGERNQLVQLNSSQLYQVVDRLSRA--VNNGQPVLNGNESIWSDIDALIKNVAV----QNNVKVWFNNKGWAAMASYMNAMNNVILRSKLPPGK-DPAQYGITVSNHPMAPTNKQIERDTLNSAWISVLVAIGVIFAMSFIPASFVLYLIEERVSNSKHLQFVSGVNRVTYWVSHLAWDIMNYSVSMVLCILLFLAFNERSYVSPTNAPCLVLLLFLYGWAMIPMMFPFNYLFKVPSTAFVALACVNVFLGVTSTLSTYVLEFFSD-DQELVQINTVLRQVFLILPHYCLGRGLIDMAANQLIADVAGIYVAGTAVKDPFEWDQVGRNLFALAVSGAAWFGFTL-----LIEYKFFCTSRLSSNENAVDDNEDIDVARERRRAMSAEARSDILRVENLTKVFHK----------------RRKGKFVAVDRLCF 1668

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BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Match: V4ABB8 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_212836 PE=4 SV=1)

HSP 1 Score: 392.889 bits (1008), Expect = 1.086e-113
Identity = 298/865 (34.45%), Postives = 451/865 (52.14%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN-----FNAQKENFRKGI------------------------------SNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNF-------NRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNN----KWSPIP--NGNIPLISPECDCNTTGYQICNDPR-SGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLS--------RKLYGGFQF--VLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGY---AK-YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYR-MLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIY 2404
             DRIAIIS GKL CCGSS+FLK KFG GY L LVK       N   ++   G+                              S S  ++  F++ ++ +A++  +  T+  + LP    +S  F  LF  L+     L   S+GLSDTSLEEVF+ VAD+    N +   ++   +N  +   +  + N+   ++  +L +    + S+ S          N   + L G+ L+  Q + L IKRFH+ +R+KKG   E+ILP   + L IA   ++ PL + P +E+ PWL +PK    NL  FY               N N  + L + LE    S     G RCMNP +Y    Y C  E  +N    KW+  P   GN+ + SP CDC + G+  C  P+ +GGP  S   + ++D L N+T  NISD+LL + P  S           Y G  F  + P     SS+++        L +  N  Q   N S L     ID L + F    +  +  ++W N+KG+ S  +Y N+ +N++LRS+L  +     DYGI+  N P+   Q     + +   ++++ +AI VIF +SFIPASF+IFL+EERVS SK  QFVSGINP +YW+S F WD++ Y++P  + ++IF+AFD +SY+ + N    + LL  YG AIIP MYPFS   S  S+AFV ++  N+ +G ++T+STFI++++E +D+     N ILK VFL+ P Y LGRG+ID++ N ++Y++T  +   AK  +   W++    L SL +L + ++I+  +IE        YR  +K  Y        ED D+S EK R+ S +  +DVL + NL+K++
Sbjct: 1088 GDRIAIISHGKLCCCGSSLFLKSKFGSGYYLTLVKQDGNGAVNVDDDDDEDGLKKALNDDDGLRPSTADVDEGFGESNGSTTGSLSVGRITGFVQKYVKNAQLVEDNSTELCYQLPTEAMSSGDFEALFTQLERSHHELGIDSFGLSDTSLEEVFLAVADE---TNVDDLTDEATRNNFRKKKKFNFLRNRRSRIEHTELVEDTDDNVSIASSTLENRVGFANSGVQKLHGWSLIFNQFLALFIKRFHHVRRSKKGFVCEIILPAGFVALAIAFSLILPPLVTEPPLELHPWLYVPKKSEPNLYMFY--------------SNDNPRSTLANSLEQALLSK-PWVGTRCMNPDVYSIDGYPC--EGSSNSQYLKWTERPKMTGNLTIDSPSCDC-SRGFPDC--PKGAGGPTPSMSYLPTTDYLYNMTARNISDWLLAHIPSFSICFDMFIFHYRYAGISFGDINPLADVNSSQIVD---IINRLSEAANGGQPIVNNSFLTD---IDTLARGF----LTRNVAKVWYNNKGWASSVSYMNVLNNMILRSKLPANKDP-ADYGITTINHPMAYNQKQFSAEAILTSVIDLIVAICVIFAMSFIPASFLIFLIEERVSDSKHMQFVSGINPTIYWISTFAWDMVNYLVPATLCVLIFLAFDQESYVSASNFPCLLALLFLYGWAIIPLMYPFSRLFSVSSSAFVTISCANVFLGVVSTLSTFIVELLEQSDKELADINTILKSVFLVLPHYCLGRGLIDMTRNQLQYDLTKQFFPDAKPSNILAWDLVGRNLFSLAMLGIFFFILNWLIE--------YRFFIKPRYVKESEDTNEDIDVSREKQRVLSGEADNDVLVLKNLSKVF 1910

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BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Match: N1PB02 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_226736 PE=4 SV=1)

HSP 1 Score: 368.237 bits (944), Expect = 3.158e-105
Identity = 278/840 (33.10%), Postives = 438/840 (52.14%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN---------FNAQKENFRKGISNSGD-KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNE-KLIPDNLNRIAVYG-----------------DIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMP-KSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNG-NIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKI------KKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIY 2404
             DRIAII+QGKL C GSS+FLK  FG GY L LVK+          + + EN  +   N+G+     FI   +P+A +      + ++ LP + S++  F  LF +LD  + +L  LSYG+SDT+LEEVF++VA++  + N  ++ + +   + L    +Y                  D E+ E  LD  D N  + V  + IS N   ++K+  G  L+ +Q + + IKRF+Y +R+KK   ++                        PAMEI PWLM P K +  +L TF+          +N L ++     + D L  +        G+RCM+P +Y    +RC  + ++++WS +    + P    EC C + GYQ C    +G   + Y ++ ++D++ N+TG NISD++LK   +  ++ YGG  F   +    ++    DS F +     +  + A  + +N+     I  L+   K    K +  +IW N+KGYVSM AY NI +NL+LR+ L         YGIS+ N P+    S  +   +   I+++ +++ VIF +  IPASFV+FL+EERVSGSK  QFVSG+NP VYWV+NF WD++ Y++  I+ I+IF+AF   +Y+   NA   + LL+ YG A  P MYP S F + PS+AFV+L   N+ +G I+T+STFIL+     ++     N I+ KVFL+ P Y LGRG+ID++ N +  ++ +   +      F W++    L SL +L + ++ + I IE       +Y M  +S    +I         ED D+  E+ R+       D+L +  LTK+Y
Sbjct: 1093 GDRIAIINQGKLCCVGSSLFLKSNFGGGYYLTLVKDERKGDSASTSDVKVENATED-GNAGEISTTAFIMERVPEAVLVESIGIEMTYQLPNDKSHTASFEKLFRDLDAHLSSLGLLSYGVSDTTLEEVFLKVANESEEANHLSEEDVRQGTERLTDGGMYARPVTRLSFRKRNFFASKDRESNE-LLD-ADGNPDSAVSTASISCNGTGSYKV-TGLSLIPRQFLAIFIKRFNYLRRSKKAFISQE-----------------------PAMEIHPWLMSPSKLQDSHLFTFF----------SNDLPSEAWTQAIEDLLTQK-----PGLGVRCMDPDVYSLKGFRCV-DAEDSQWSNVEEDFDEP---EECSCES-GYQRCPKGAAGAEASKY-LLPTTDEMYNMTGRNISDWILKTSQEYIKRRYGGLTFGERNDLLRANDTEVDSIFAQ-----LATAAAGDDTNNVTLPGLILDLENLIKNIATKRN-AKIWFNNKGYVSMVAYMNIMNNLVLRAHLPPDTDPS-RYGISLINHPMNRTSSQLYAYTLKASIVDVMISVSVIFAMCLIPASFVLFLIEERVSGSKHLQFVSGVNPVVYWVANFTWDMLNYLVSGILCILIFVAFQQNAYVSQTNAPCLVSLLLLYGWAATPMMYPASHFFNVPSSAFVILGCMNIFLGIISTLSTFILEAF--MEQELDEINAIIMKVFLVLPHYCLGRGLIDMTRNQLVADIFENLGETFFQSPFTWDIVGRNLLSLSILGVFFFFLNICIEYKFW---IYSMKCISPCKEQIPVNVEETDEEDIDVVRERERVTLGAASGDILTLEGLTKVY 1872

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BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Match: A0A3P9HY39 (Uncharacterized protein OS=Oryzias latipes OX=8090 PE=4 SV=1)

HSP 1 Score: 350.517 bits (898), Expect = 2.464e-99
Identity = 267/872 (30.62%), Postives = 448/872 (51.38%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN----FNAQKENFRKGI---------------------------SNSGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE-ETKNEKLIPD-----------NLNRI---AVYGDIENQ---EPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMN----PSIYRSTHYRCF--PEYKNNKWSPIPNGNIPLI--SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKT---FKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNR 2410
             DRIAIIS GK++CCGSS+FLK+ FG GY L LV++      AQ+     GI                           SN  D   + QF++ H+P+A        + +F+LP   +    F+ LF  LD+ +D L   SYG+SDT+LEE+F++VA+D     E     E ++ D           +++R    A  G+++++   +    +ED    A V+         R   ++ G+ L++QQ + L IKRFH+A+R++KG+ A+++LP + + L +    +V    + P++E+ PW+   ++      TFY          +N +    +++ + + L      D    G RCM     P +  S+    +  P    +      NGN  +   SP C C+T G  I    C     G P    R+  ++D L NLT  N++D+LLK +    +K YGG      S  G +S+++            +   +     +NL    + D +QK     K  G + +  ++W  +KG+ SM ++ ++ +N +LR  L +       YG+SVSN P+ + +    L  +     ++ ++I VIF +SFIPASFV+FL++ERVS +K  QFVSG+NP VYWV++F+WDI  YIIP  +++ IFI F  ++Y+  +N  A ILLL+ YG AI P MYP SF  + PSTA+VVL   NL +G   +++TF++++ +  DE+    N I+K+V LIFP + LGRG++D++ N    N+   + +    D   W +  + L ++ +   + +   +     +I    +   ++S    + ++ ED D++ E++R++  +  +DVL++ +LTK+Y R
Sbjct:  753 GDRIAIISHGKMRCCGSSIFLKKSFGSGYYLTLVRSGTEVMTAQRSGIISGIAEEKPTESDCPSSSSLDEDGGCQSSDNSNPADLKHVTQFVRRHVPEAVFLESIGQEITFILPYARARDGTFATLFQELDKVMDKLGLTSYGVSDTTLEEIFLKVAEDTGVDKELSPTKEPVVKDYKKDSRESKRRSMSRFHGKAAKGNMKDELKKKLSNKVEDFKNSASVN--------GRGSVVITGWKLIRQQFLALFIKRFHHARRSRKGLIAQVVLPAIFVCLALVFSLIVPSFTAYPSLELQPWMYDSQT------TFY----------SNDMPEDANVSRVVETL-----VDNPGFGTRCMEGNPIPRLPCSSGASDWFSPSVDQSVADIFLNGNWSMSNPSPSCQCSTPGRTIIMPDCPPGAGGLP-PPQRVQNTTDTLLNLTSINMTDFLLKTYEHAGKKRYGGI-----SVGGINSQVL------------LTEVEIEEAFANLEPPGYGDTIQKAEMVLKKLGTRNN-VKVWFYNKGWHSMVSFLSVVNNGILRGYLPEGQ-DLRQYGLSVSNHPLNLSKEQLSLSAMATTSSDVVVSICVIFAMSFIPASFVLFLIQERVSKAKHLQFVSGVNPTVYWVASFVWDICNYIIPCFLVVGIFICFQQKAYVSPQNLPALILLLVMYGWAITPMMYPASFIFTVPSTAYVVLTCLNLFIGINGSVATFVMELFK--DESITKINNIVKQVLLIFPHFCLGRGLMDMARNQAMANVFSNFGEDRFEDPLSWNMVGKNLIAMSIQGAVMFAFTL-----LIQHKFFYKPRLSLPKVQSEEKEDVDVARERHRVHEGRANNDVLRICDLTKVYPR 1568

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BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Match: A0A3P9HY72 (Uncharacterized protein OS=Oryzias latipes OX=8090 PE=4 SV=1)

HSP 1 Score: 350.517 bits (898), Expect = 2.684e-99
Identity = 267/872 (30.62%), Postives = 448/872 (51.38%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN----FNAQKENFRKGI---------------------------SNSGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE-ETKNEKLIPD-----------NLNRI---AVYGDIENQ---EPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMN----PSIYRSTHYRCF--PEYKNNKWSPIPNGNIPLI--SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKT---FKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNR 2410
             DRIAIIS GK++CCGSS+FLK+ FG GY L LV++      AQ+     GI                           SN  D   + QF++ H+P+A        + +F+LP   +    F+ LF  LD+ +D L   SYG+SDT+LEE+F++VA+D     E     E ++ D           +++R    A  G+++++   +    +ED    A V+         R   ++ G+ L++QQ + L IKRFH+A+R++KG+ A+++LP + + L +    +V    + P++E+ PW+   ++      TFY          +N +    +++ + + L      D    G RCM     P +  S+    +  P    +      NGN  +   SP C C+T G  I    C     G P    R+  ++D L NLT  N++D+LLK +    +K YGG      S  G +S+++            +   +     +NL    + D +QK     K  G + +  ++W  +KG+ SM ++ ++ +N +LR  L +       YG+SVSN P+ + +    L  +     ++ ++I VIF +SFIPASFV+FL++ERVS +K  QFVSG+NP VYWV++F+WDI  YIIP  +++ IFI F  ++Y+  +N  A ILLL+ YG AI P MYP SF  + PSTA+VVL   NL +G   +++TF++++ +  DE+    N I+K+V LIFP + LGRG++D++ N    N+   + +    D   W +  + L ++ +   + +   +     +I    +   ++S    + ++ ED D++ E++R++  +  +DVL++ +LTK+Y R
Sbjct:  753 GDRIAIISHGKMRCCGSSIFLKKSFGSGYYLTLVRSGTEVMTAQRSGIISGIAEEKPTESDCPSSSSLDEDGGCQSSDNSNPADLKHVTQFVRRHVPEAVFLESIGQEITFILPYARARDGTFATLFQELDKVMDKLGLTSYGVSDTTLEEIFLKVAEDTGVDKELSPTKEPVVKDYKKDSRESKRRSMSRFHGKAAKGNMKDELKKKLSNKVEDFKNSASVN--------GRGSVVITGWKLIRQQFLALFIKRFHHARRSRKGLIAQVVLPAIFVCLALVFSLIVPSFTAYPSLELQPWMYDSQT------TFY----------SNDMPEDANVSRVVETL-----VDNPGFGTRCMEGNPIPRLPCSSGASDWFSPSVDQSVADIFLNGNWSMSNPSPSCQCSTPGRTIIMPDCPPGAGGLP-PPQRVQNTTDTLLNLTSINMTDFLLKTYEHAGKKRYGGI-----SVGGINSQVL------------LTEVEIEEAFANLEPPGYGDTIQKAEMVLKKLGTRNN-VKVWFYNKGWHSMVSFLSVVNNGILRGYLPEGQ-DLRQYGLSVSNHPLNLSKEQLSLSAMATTSSDVVVSICVIFAMSFIPASFVLFLIQERVSKAKHLQFVSGVNPTVYWVASFVWDICNYIIPCFLVVGIFICFQQKAYVSPQNLPALILLLVMYGWAITPMMYPASFIFTVPSTAYVVLTCLNLFIGINGSVATFVMELFK--DESITKINNIVKQVLLIFPHFCLGRGLMDMARNQAMANVFSNFGEDRFEDPLSWNMVGKNLIAMSIQGAVMFAFTL-----LIQHKFFYKPRLSLPKVQSEEKEDVDVARERHRVHEGRANNDVLRICDLTKVYPR 1568

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Match: abca4a (retinal-specific ATP-binding cassette transporter-like [Source:NCBI gene;Acc:103024609])

HSP 1 Score: 327.791 bits (839), Expect = 6.324e-95
Identity = 264/889 (29.70%), Postives = 429/889 (48.26%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRK-------------------------------GISNSGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRV-ADDPAKINEETKNEKLIPDNLNRIAVYGD----IENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNN---KWS-PIPNGNIPLI-----------SPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSR-----------KLYGGFQF--VLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNL-NSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMI--LEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF--------NNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYN 2407
            SDR+AIISQG+L CCGS +FLK   G G+ L LV+         RK                               G    GD   +   +  H+P+A++      + +F+LP        ++ LF  L+E + ++   S+G+SDTSLEE+F++V AD    + +   + + + +  +R +V+ D    +  +EP       N Q        S    +  + ++G  L+ +Q + L IKRFH+  R+ K  FA+++LP   + + +    +V P    P++ +SPW+     R     TF+  E       +   G K   + L +R            G RCM         Y C     NN   +W  P+ N  +  +           SP+C C+T    T   +C +  +GG P   RI ++ D L +LTG NISDYL+K +P L R           + YGG      LP   G S K I D+   E+L    N +   H +  L ++  F+ Y++  + +        ++W N+KG+ +MPA+ N+ +N +LR+ L  +A    +YG++V N P+ + +    L  VN +   ++  +A+ VIF +SF+PASFV++L++ERV+ +K  QFVSG++P VYW +NFLWD++ Y +   +++ IFI FD + Y    N  A I LL+ YG ++ P MYP S+  S PSTA+V L+  NL +G  ++  TFILD+  D+  T    N++LK+V LIFP + LGRG+ID++   I   + D YA++      D F W    + +  +                G I  +L  +++  +F           +   ED D++ E+ R+       D+L + +L+K Y+
Sbjct: 1177 SDRVAIISQGRLHCCGSPLFLKSMLGAGFYLTLVRRMKDDTPPTRKEGQCDCKDDCSCKCSICTEYKESTCGQTKSAGRQMDGDVETITNLVHHHVPEARLVEAVGQELTFLLPSRGFKHRAYASLFRELEETLADIGLSSFGVSDTSLEEIFLKVTADGETSLGKSAADLRALQET-SRSSVFRDTTVTVNTEEPEDKKACANGQP--TAGGSSSGEGQGSRQVKGVSLVVKQFLALLIKRFHHTTRSGKDFFAQIVLPASFVLVSLMFTLIVPPFGEYPSLTLSPWIY---GRQF---TFFSNEQ------SEMEGMKYFADVLLNR---------PGFGTRCMVDEPLE--EYPC-----NNITTEWEKPLVNPALVDVLNKSQWTELRPSPDCQCSTPTKLTMLPVCPE-GAGGLPLPQRIQSTGDVLIDLTGRNISDYLVKTYPTLIRTSLKSKYWVNEQRYGGISVGGRLP-VVGLSPKTIQDTA--EQLGGIFNITAGKHVKRALRDTGTFLRYMETEYNV--------KVWYNNKGWHAMPAFLNVANNAILRAHLPTNA-NPSEYGVTVINHPLNLTKEQ--LSEVNVLTTSVDAVVAMCVIFAMSFVPASFVLYLIQERVTQAKHLQFVSGVSPLVYWTANFLWDMISYSVSAALVVQIFINFDKKCYTSPANLHALIALLMLYGWSVTPMMYPMSYVFSVPSTAYVSLSCLNLFIGINSSAITFILDLF-DSSTTLYMFNQVLKRVLLIFPHFCLGRGLIDMA---INQAVMDVYAQFGEDYSLDPFSWNFVGKNVVCMAA-------------EGFIYFILNILIQYRFFLEHWMPDSKKPLIVDEDLDVAKERERIYRGGSSSDILHIRDLSKTYS 2002

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Match: ENSAMXT00000022236.2 (pep primary_assembly:Astyanax_mexicanus-2.0:21:13397857:13560117:1 gene:ENSAMXG00000021540.2 transcript:ENSAMXT00000022236.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 323.553 bits (828), Expect = 1.522e-93
Identity = 265/849 (31.21%), Postives = 432/849 (50.88%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILV--------KNFNAQKENFR--KGISNSG----DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPD------NLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGI--RCM--NPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLI-----------SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXE-RGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFN 2419
             DRIAIIS G++ CCGSS+FLK+ +G GY L LV        +   +Q ++F   +GI +S       L   ++ H+P+A        +  ++LP   S    F+ LF  LD E + L   SYG+SDTSLEEV          ++ + K + L+ D           ++   +E +E      D  +Q+      + LN  +   ++ G+PL++ Q + L IKRFH+A+R++KGI A+++LP   + L +    +V P    P++E+ PW M  K +    NTFY  +     ++T                 S  RS L E G   RCM  NP       Y C P    +  +P  +  I  I           SP+C C+T    I    C     G PP   R  +++D L+NLT YN++D+LLK + K  +  YGG      S  G +S+++            +N S+     S+  +L     + +T     + TS + +W  ++G+ ++ ++ N+ ++  +      S ++   YGIS  N P+ + +      +      ++ ++I VIF +SFIPASFV+FL++ERVS +K  QFVSG+NP  YWV+NF WD+  YI+P +I+IIIF+ F  +SY+   N  A ILLLI YG +I P MYP SF  S PSTA+VVL   NL +G   +++TF++++ +D + T    N+I+K+V LIFP + LGRG+ID++ N     +     +    D   W++  + L ++ +  ++ +   ++I+ +      L + L VS         ED D++ E+ R++     +D+L++ +LTK+   +F+
Sbjct:  859 GDRIAIISHGRVCCCGSSLFLKKTYGSGYYLTLVQANQERGARKHQSQCDDFSLDEGIGSSSLSNVADLSALVRRHVPEAVFLEVLGQELVYILPYTGSKDGSFASLFKELDLEKERLGISSYGISDTSLEEVHTLAQTHTHTLSIQYK-DTLVRDWKRSSRESRTHSISSAMEQKEKESSKCDDQRQS------VCLN-GKGSSVMSGWPLIRHQFLALFIKRFHHARRSRKGIIAQVVLPAFFVCLSLIFSLIVPPFVEYPSLELQPW-MYGKPQ----NTFYSTDRPTEAAVT-----------------SVTRSLLNEPGFGTRCMESNPI----PKYPCVPAGATDWSTPAVDPAILKIFQDGNWTMQNPSPDCQCSTPERNIMLPDCQPGAGGLPPP--RTQSTTDTLHNLTSYNMTDFLLKTYAKSGKIRYGGI-----SVGGVNSQVM------------LNESEIIAAVSDFKALFNSTQVSQT-----LCTSLSLVWFYNQGWHAIASFLNV-ASNAILRASLPSRLQPKLYGISAFNHPLNLTKQ----QMSAAFSTDVVVSICVIFAMSFIPASFVLFLIQERVSKAKHLQFVSGVNPAGYWVANFTWDMCNYIVPCLIVIIIFLCFQQKSYVSPPNLPALILLLILYGWSITPMMYPASFLFSVPSTAYVVLTCINLFIGINGSVATFVMELFDDPNIT--RINDIMKQVLLIFPHFCLGRGLIDMAKNQAMATLFSSLGEDRFKDPLGWDMVGKNLFAMAVEGVVMFGFTLLIQYKFCWKPGLVKGLPVSL------GQEDEDVARERERVHKGGAENDLLRICDLTKVLLLSFS 1636

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Match: abca4a (retinal-specific ATP-binding cassette transporter-like [Source:NCBI gene;Acc:103024609])

HSP 1 Score: 321.242 bits (822), Expect = 1.181e-92
Identity = 252/874 (28.83%), Postives = 418/874 (47.83%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRK-------------------------------GISNSGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRV-ADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINP--LTDRLESEYRSD--LGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNT----TGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSR-----------KLYGGFQF--VLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNL-NSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMI--LEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY------DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYF--------NNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYN 2407
            SDR+AIISQG+L CCGS +FLK   G G+ L LV+         RK                               G    GD   +   +  H+P+A++      + +F+LP        ++ LF  L+E + ++   S+G+SDTSLEE+F++V AD    + +   ++K                N +P                  S    +  + ++G  L+ +Q + L IKRFH+  R+ K  FA+++LP   + + +    +V P    P++ +SPW+     R     +  + E +      + L N+       + D    EY  +    E     +NP++    +         ++W+ +        SP+C C+T    T   +C +  +GG P   RI ++ D L +LTG NISDYL+K +P L R           + YGG      LP   G S K I D+   E+L    N +   H +  L ++  F+ Y++  + +        ++W N+KG+ +MPA+ N+ +N +LR+ L  +A    +YG++V N P+ + +    L  VN +   ++  +A+ VIF +SF+PASFV++L++ERV+ +K  QFVSG++P VYW +NFLWD++ Y +   +++ IFI FD + Y    N  A I LL+ YG ++ P MYP S+  S PSTA+V L+  NL +G  ++  TFILD+  D+  T    N++LK+V LIFP + LGRG+ID++   I   + D YA++      D F W    + +  +                G I  +L  +++  +F           +   ED D++ E+ R+       D+L + +L+K Y+
Sbjct: 1177 SDRVAIISQGRLHCCGSPLFLKSMLGAGFYLTLVRRMKDDTPPTRKEGQCDCKDDCSCKCSICTEYKESTCGQTKSAGRQMDGDVETITNLVHHHVPEARLVEAVGQELTFLLPSRGFKHRAYASLFRELEETLADIGLSSFGVSDTSLEEIFLKVTADGETSLGKSAADKK-------------ACANGQP-------------TAGGSSSGEGQGSRQVKGVSLVVKQFLALLIKRFHHTTRSGKDFFAQIVLPASFVLVSLMFTLIVPPFGEYPSLTLSPWIY---GRQFTFFSNEQSEMEGMKYFADVLLNRPGFGTRCMVDEPLEEYPCNNITTEWEKPLVNPALVDVLN--------KSQWTELRP------SPDCQCSTPTKLTMLPVCPE-GAGGLPLPQRIQSTGDVLIDLTGRNISDYLVKTYPTLIRTSLKSKYWVNEQRYGGISVGGRLP-VVGLSPKTIQDTA--EQLGGIFNITAGKHVKRALRDTGTFLRYMETEYNV--------KVWYNNKGWHAMPAFLNVANNAILRAHLPTNA-NPSEYGVTVINHPLNLTKEQ--LSEVNVLTTSVDAVVAMCVIFAMSFVPASFVLYLIQERVTQAKHLQFVSGVSPLVYWTANFLWDMISYSVSAALVVQIFINFDKKCYTSPANLHALIALLMLYGWSVTPMMYPMSYVFSVPSTAYVSLSCLNLFIGINSSAITFILDLF-DSSTTLYMFNQVLKRVLLIFPHFCLGRGLIDMA---INQAVMDVYAQFGEDYSLDPFSWNFVGKNVVCMAA-------------EGFIYFILNILIQYRFFLEHWMPDSKKPLIVDEDLDVAKERERIYRGGSSSDILHIRDLSKTYS 1975

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Match: zgc:172302 (zgc:172302 [Source:ZFIN;Acc:ZDB-GENE-081205-5])

HSP 1 Score: 318.546 bits (815), Expect = 7.560e-92
Identity = 273/867 (31.49%), Postives = 424/867 (48.90%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDL--NQQAFVDKSLISLNFNRNHKL---------LRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCM--NPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSL-KFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKY---DAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKK--TEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLCF 2500
             DRIAIISQGKL CCGSS+FLK   G GY L  VK    ++   R   S SG+ L+   + ++  A++  +   +    LP   S     +     LD+       +SYGLSDT+LEE+F++VA++     E        PD           +  EP  D + +  NQQ     SL+         L         L G+ L  QQ+  L  KR  YA R++KG  A+++LP L I + +    +V P+   PA+E+ PW+                  Q  F       N    +P    L S      G  G +C+  +P I  ST ++ F           PN  +   SP+C C+T   +     C +   G PP   + +T  D L NLTG NISDYL+K +P++ +K            YGGF          S  LIG      +L + V A +  +  +  +SL + +D L   F     + +  ++W N+KG+ +M ++ NI +N LLR+ L     +   +GI+  N P+ + +      ++    +++ L+I VIF +S +PASFV+FL+EERVS +K  QFVSG+ P +YW +NF+WD++ Y +P  ++++IFI F  Q+Y+  KN  A +LLL+ YG AI P MYP SF  S PSTA+V L + NL +G   +++TF+L++   T+E  R  N ILKKVFLIFP + LGRG+ID++ N    +      K        W+   + L ++ +  ++++I  I+++     R      ++ +F   +     ED D+  E++R+ + +  DD+L +I+L+K+Y                      +K AVN LC 
Sbjct: 1003 GDRIAIISQGKLCCCGSSLFLKSHLGTGYYLTAVK----KELQSRTPTSASGNGLVALAQHYVSGARLVEDVGREVVINLPHAASEDGTLALFLAELDKRQAEFGIISYGLSDTTLEEIFLKVAEETGVDAE--------PDEAATPPAVSPSQQGEPPEDRDAVLFNQQV----SLLYTEAQETDPLSGDGRGSVSLTGWGLTWQQLRALFTKRLLYATRSRKGFIAQIVLPALFILIDLLFSLIVPPMGKYPALELQPWMY---------------GEQFTF-----FSNDAPQDPAMQNLLSALLDPPG-FGTKCLFNSPQIPFST-WKLFNS---------PNWTMEHPSPDCMCSTEEVRRMLPDCPEGAGGLPPPQIKRLTG-DILQNLTGRNISDYLMKTYPQILKKSMKTKKWVNEFRYGGFSLGAKG----SQTLIGSL----QLEESVMAIRKQYKIAENSSLDQLLDRLPDLFTDLNSQNN-VKVWYNNKGWHAMVSFVNIMNNGLLRASLPPGPER-QKHGITAYNHPLNLTKEQLSDMVLMTTSVDVLLSISVIFAMSLVPASFVLFLIEERVSKAKHLQFVSGVKPILYWTANFVWDMLNYTVPATLVVLIFIGFQQQAYVSEKNLPALVLLLLLYGWAITPLMYPASFVFSVPSTAYVTLTSINLFIGINGSIATFVLELF--TNEHLREVNRILKKVFLIFPHFCLGRGLIDMAKNQAMADALQRLGKCHMPSPIVWDFVGKNLFAMAVEGVVFFIFTILLQYKFFIRC-----RLPWFEPVLPPLCAEDEDVGRERDRVKNGRTQDDILTLIDLSKVY-------------------KSGKKPAVNRLCL 1785

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Match: zgc:172302 (zgc:172302 [Source:ZFIN;Acc:ZDB-GENE-081205-5])

HSP 1 Score: 312.383 bits (799), Expect = 1.018e-89
Identity = 266/889 (29.92%), Postives = 419/889 (47.13%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN--------------FNAQKENFRKGISNSGDK--------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPI--PNGNIPLISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSL-KFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK------YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRML--------KVSYFNNKIKK--TEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLCF 2500
             DRIAIISQGKL CCGSS+FLK   G GY L  VK                 A  ++ R   +  G +        L+   + ++  A++  +   +    LP   S     +     LD+       +SYGLSDT+LEE+F++VA++     E        PD           +  EP  D ++ +  +   +  +SL          G+ L  QQ+  L  KR  YA R++KG  A+++LP L I + +    +V P+   PA+E+ PW+                  Q  F       N    +P    L S      G  G +C+       T +   P+   + W     PN  +   SP+C C+T   +     C +   G PP   + +T  D L NLTG NISDYL+K +P++ +K            YGGF          S  LIG      +L + V A +  +  +  +SL + +D L   F     + +  ++W N+KG+ +M ++ NI +N LLR+ L     +   +GI+  N P+ + +      ++    +++ L+I VIF +S +PASFV+FL+EERVS +K  QFVSG+ P +YW +NF+WD++ Y +P  ++++IFI F  Q+Y+  KN  A +LLL+ YG AI P MYP SF  S PSTA+V L + NL +G   +++TF+L++   T+E  R  N ILKKVFLIFP + LGRG+ID++ N     M D   +       +  +W+   + L ++ +              GV+  +   +L        ++ +F   +     ED D+  E++R+ + +  DD+L +I+L+K+Y                      +K AVN LC 
Sbjct: 1055 GDRIAIISQGKLCCCGSSLFLKSHLGTGYYLTAVKKELQSRTPTSASGKLLAADTDSTRSDDTGLGSEVNSSVISGLVALAQHYVSGARLVEDVGREVVINLPHAASEDGTLALFLAELDKRQAEFGIISYGLSDTTLEEIFLKVAEETGVDAE--------PDEAATPPAVSPSQQGEPPEDRDETDPLSGDGRGSVSLT---------GWGLTWQQLRALFTKRLLYATRSRKGFIAQIVLPALFILIDLLFSLIVPPMGKYPALELQPWMY---------------GEQFTF-----FSNDAPQDPAMQNLLSALLDPPG-FGTKCLCTGENVGTKFNS-PQIPFSTWKLFNSPNWTMEHPSPDCMCSTEEVRRMLPDCPEGAGGLPPPQIKRLTG-DILQNLTGRNISDYLMKTYPQILKKSMKTKKWVNEFRYGGFSLGAKG----SQTLIGSL----QLEESVMAIRKQYKIAENSSLDQLLDRLPDLFTDLNSQNN-VKVWYNNKGWHAMVSFVNIMNNGLLRASLPPGPER-QKHGITAYNHPLNLTKEQLSDMVLMTTSVDVLLSISVIFAMSLVPASFVLFLIEERVSKAKHLQFVSGVKPILYWTANFVWDMLNYTVPATLVVLIFIGFQQQAYVSEKNLPALVLLLLLYGWAITPLMYPASFVFSVPSTAYVTLTSINLFIGINGSIATFVLELF--TNEHLREVNRILKKVFLIFPHFCLGRGLIDMAKNQA---MADALQRLGTKQTLEPLEWDFVGKNLFAMAV-------------EGVVFFIFTILLQYKFFIRCRLPWFEPVLPPLCAEDEDVGRERDRVKNGRTQDDILTLIDLSKVY-------------------KSGKKPAVNRLCL 1856

HSP 2 Score: 55.0694 bits (131), Expect = 4.125e-7
Identity = 42/148 (28.38%), Postives = 69/148 (46.62%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVA----DDPAKINEETKNEKLIPDNLNR 439
            R+AI+  G+ QC GS   LK +FGDGY +IL    +A  ++           +  +IK+      ++        + LP   SNSC  + +F  L    + L    Y +S T+L++VF+  A    DD  +++  T N  L+    +R
Sbjct: 2035 RMAIMVNGRFQCLGSVQHLKNRFGDGYTIIL--RLSAPPKD--------PCPVDAYIKNSFTGIVLKERHHNVLQYQLP---SNSCSLARVFDVLSNNYEELGVTDYSISQTTLDQVFVNFAKEQTDDDDQLSGVTVNGGLVAAQTSR 2169

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002495.1 (pep scaffold:Pmarinus_7.0:GL480265:53:27909:1 gene:ENSPMAG00000002218.1 transcript:ENSPMAT00000002495.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 171.014 bits (432), Expect = 4.985e-44
Identity = 157/569 (27.59%), Postives = 262/569 (46.05%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK---------------------NFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAK-------INEETKNEK---LIPDNLNRIAVYGDIENQEP--FLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMN-PSIYRSTHYRCFPEYKNNKWSPI-------PNGNIPLISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSS---KLIGDSPFWEELR-DFVNASQANHNQSNLNSLKFIDYLQKTFK----IYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQ 1549
             DRIAIIS G+L+CCGSS+FLK  FG GY L +VK                      F + + N     +N    + + ++ H+PDA++      + +++LP + +    F+ LF  LDE++  L   SYG+SDT+LEE+F++VA++PA        +    +N K   L P +   I        + P    +LE LN+   +D         +  + + G  L+  Q   L IKRFH+A+R++KG  A++ILP + + L +    ++ P    P +++ PW+   +   ++ +     EN    S+ + L NK                     G RCMN  SI  +       E+     SP         N ++   SPEC C+  G ++    C +  +GGPP   R+  ++D L +L+G NISDYL+K +P+  RK      +V    +G  S   K +  S   +++   F N  +  H ++     K +D L    K      G K +  ++W N+KG+ ++ A+ N+ +N  +      +     DYGI+  N P+ + +
Sbjct:  561 GDRIAIISHGRLRCCGSSLFLKNAFGAGYYLTMVKRSGSGGSNSSCLAGLASSSDEGFGSDESNPDSIAANHVSSVTRLLQQHVPDARLIENFGQELTYLLPSHGAKDGTFALLFKELDEKLAELGVSSYGVSDTTLEEIFLKVAEEPAANSHFTNGVKLSARNSKYTYLQPVHAGCICKNYSTCKKAPAELGELEKLNE---LD--------GKGTQQISGVQLILLQFKALFIKRFHHARRSRKGFVAQIILPAVFVCLALVFSLIIPPFGKYPMLQLQPWMYGEQYTFLSNDA---PENVKTNSLYDALLNKPGF------------------GTRCMNGESIPDAACVETKSEWVQPPMSPAMARTMQSRNWSMEDPSPECRCSGEGRRVILPDCPE-GAGGPPPMQRVQNTTDTLEDLSGRNISDYLVKTYPQAIRKSLKHKYWVNEIRYGGLSVGKKKLSHSASPKDMDIVFTNVKRVFHIEN-----KAVDVLYSGVKDMVSFLGPKETI-KVWFNNKGWHAIVAFMNM-ANNAVLRSSLPAGTDPSDYGITAYNHPLNLTK 1089

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Match: abca12 (ATP-binding cassette, sub-family A (ABC1), member 12 [Source:ZFIN;Acc:ZDB-GENE-030131-9790])

HSP 1 Score: 141.354 bits (355), Expect = 1.831e-34
Identity = 124/449 (27.62%), Postives = 212/449 (47.22%), Query Frame = 2

Query: 1130 NLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDII---EDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKYDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTE-------DFDISLEKNRMNSEQKF------DDVLQVINLTKIY---NRTFN 2419
            NL+G ++ +YL+    +   K YGG+ F LP +                              S+L  +     L K ++      +  ++W N +GY ++PAY N F+NLLL   L          GISV++ P   +Q ++  D++ Q + +  +AI ++ G S +  SF   +V ER++GSKR Q +SG++P  YW  NF +D++ Y +   + I +  AF   +Y  + N  A  LLLI +G A +P MY  S   S    AFV   + N+++G  T +STF+++ +    D+   +   N I++ +FL+FPQ+ LG G++ LS    K  + +   K    D      + +S   + +  W  + +   G++   L  +L  S+     +K         D D+  E++R+  + +       DD LQ++ L K Y   NR+F 
Sbjct: 1059 NLSGEDVEEYLMGTTCQYLLKRYGGWSFGLPHS----------------------------TTSDLEVVPDNRTLTKVWR------NHMKVWYNPEGYHALPAYVNSFNNLLLWDNLPDGEHPGDYKGISVNSKPYAGQQLSQ--DMILQNLGDTGVAICILLGFSILTGSFATAVVRERITGSKRLQQISGVSPTFYWAVNFTYDMVSYTVTTGLCIAVIAAFHLPAYTDNSNLGAVSLLLILFGFASLPWMYLISGVFSEEEMAFVTYISINIILGVSTIISTFLVNFLYLSSDSQSLYNAYN-IMRWLFLVFPQFCLGWGLVSLS----KQRLMEDIMKLLGSD-----PQESSSFAMDITGWPFVALAVNGIVCFTLRLVLTDSFIRWWRRKAVEPGQPELDTDVQAERSRVEEQSRVVDAATPDDTLQLVGLRKRYRLLNRSFT 1461

HSP 2 Score: 71.633 bits (174), Expect = 6.187e-13
Identity = 44/141 (31.21%), Postives = 77/141 (54.61%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSG-DKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIP 424
            D++AI+  G+ +C G+   LK +FG+G+ + L           R    NS   ++ +FI SH P A ++ + ++Q  F +P   SN+ K S +F+ L++E ++L+   Y +S T+L++VFI  A     + EE+ N    P
Sbjct: 1652 DKLAIMVNGQFKCLGTLQHLKNRFGNGHMIKL-----------RLSSGNSKVTEVTEFITSHFPGAYLKEQHISQLEFQVP---SNAGKLSEIFIALEKEKESLSIQHYSISQTTLDQVFINFARQQIDMEEESSNADARP 1778

HSP 3 Score: 70.0922 bits (170), Expect = 1.819e-12
Identity = 67/269 (24.91%), Postives = 109/269 (40.52%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFN----AQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWS------FVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFI---RVADDPAKINEETKNEKLIPDN----LNRIAVYG-------------------DIENQEPFLDLEDLNQQAFVDK-----------SLISLNFNRNHKL----LRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAE 655
            SDRIA++  GKL+CCGS  +LK  +G G  L L K       +Q            ++++  ++S +  A +++   +  +      F+LP +  N    S   V L+E ++ L    Y +SDT+LEEV +   RV  +PA +          P +    L +    G                   DI N+ P  +   +N +                 L SL     H +    + G  LL ++   L  KRFH+ +R+ KG  A+
Sbjct:  581 SDRIAVLEHGKLRCCGSPQYLKEIYGQGLTLTLTKKVRVLCLSQSVTLGSRPPFDPERVVSLVRSGVAGAALKSGEDSSGNRNADMVFLLPAHSQNVLGQS-FLVTLEENMEELGLSGYAISDTTLEEVCLRQQRVMSEPA-LGCSASARYFTPTSAASLLTKATQCGPGLYSCSQLVQEAEDQRLKDITNKSPEAESGSINSETAAPPDHTSPAASSILCLSSLWRTEKHLVKKERVTGIHLLVRKTQALIYKRFHHWRRDVKGAAAQ 847

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006988.1 (pep scaffold:Pmarinus_7.0:GL478499:147909:176415:-1 gene:ENSPMAG00000006318.1 transcript:ENSPMAT00000006988.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.8322 bits (120), Expect = 1.146e-6
Identity = 21/36 (58.33%), Postives = 29/36 (80.56%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN 109
            +D  A++SQG+L+C GSS+FLK KFG GYRL L+ +
Sbjct:  649 ADWKAVLSQGRLKCAGSSLFLKTKFGVGYRLTLITD 684

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006855.1 (pep scaffold:Pmarinus_7.0:GL486953:391:4596:1 gene:ENSPMAG00000006189.1 transcript:ENSPMAT00000006855.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.9062 bits (115), Expect = 2.349e-6
Identity = 33/125 (26.40%), Postives = 59/125 (47.20%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLE---EVFIRVA 373
            R+AI+  G  +C GS   LK +FGDGY + +           R   +    ++L+F     PDA ++    T+  +   Q  S +   + +F  +++ +D L    Y +S T+L+   +VF+  A
Sbjct:  192 RLAIMVNGHFKCLGSIQHLKNRFGDGYMITI-----------RTRSTLHVKEVLRFFSRSFPDAVLKERHHTKVQY---QLKSETLSLAAVFTKMEQVLDVLGVEDYSVSQTTLDNDPQVFVNFA 302

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Match: EDO46878 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNL9])

HSP 1 Score: 321.242 bits (822), Expect = 2.818e-93
Identity = 265/839 (31.59%), Postives = 417/839 (49.70%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----NFNAQKENFRKGISNS------------GD---------KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSL-ISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDK--LNNLTGYNISDYLLKNFPKLSRKLY-GGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNY-------IKYNMTDGYAKYDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSE-QKFDDVLQVINLTKIY 2404
             DRIAIISQGKLQCCG+S+FLK  +G+GY L L K       ++   + R  + +             GD          +  FIKSHIP A +     T+ ++VLP + +   KF  +F  LD  +  L+  SYG+SDT+LEEVF++VA++    +EE      +P   +         +  P   L+   Q    + S+  SL F+       G  LL +Q   L +KRFH+ +RN+K   A+ I+   +   +  ++  + P    PA+E++P            + F ++E   N+ +     N +   PL   L   +    G  G  CM+ +  R       P       SP+P       SP+CDC +    +C     G PP ++   TS D   +  ++G NISDYLLK + K  +K Y    + ++   +G  S   GD+          N   AN   S+  +++ +           I     +IW N+KGY ++PA+ N  SN +LR++     +    YGI+  N P+   +     +   +  +++ +AI V+F LSF+PASFV+FLV ERVS +K    VSG+ PY+YW++N++WD+  Y IP ++ + IF+AF  +SY  + N      LL+ YG +I P MYP S F S  STA++VL + NL VG   T++TFIL++ ED D+     N +LK VFL+FP Y LGRG+IDL+ N           N+T      D F W++    + ++I+   +++ + ++IE     R   ++  V      +++ ED D+  E+ R+NS      D L+++NLTK+Y
Sbjct:  569 GDRIAIISQGKLQCCGTSLFLKSHYGNGYYLTLTKKTPGLGLDSVDASERDSLGSRSSDSDPISDSVLGDYSDVYCNEKSVTSFIKSHIPSASLVEHVGTELTYVLPSHAAKEGKFQDMFEELDRNLHKLHVGSYGVSDTTLEEVFLKVAEEAQ--SEEAGTSAEVPVRRSTFTF-----SSHPVKCLQPPAQGDSKNDSVDGSLEFDDRES---GLALLLRQFFALLVKRFHHCRRNRKAFIAQ-IILPAVFVCLAMIVAQIRPFYEKPALELTP------------HMFVKEEPYENYVL---YANDDPGEPLARNLSDAFLQYPG-LGTWCMSNNCSRK------PIAFQPSLSPVPTP-----SPDCDC-SEAMNVCPAGAGGPPPPTW---TSYDGNIIQKMSGRNISDYLLKTYMKFVKKRYINKIEIMIVREYGGLS--FGDN---------YNNLPANVRNSSDPAIRRL-----------ISPRNVKIWYNNKGYHALPAFLNTLSNTVLRAKAKARGLDPSQYGITAYNHPMNYTKEQLDDETFVKRAVDVLVAICVVFALSFVPASFVVFLVSERVSKAKHLHLVSGVKPYIYWLANYVWDMCNYFIPAMLCVFIFLAFGDESYTTAMNFPPTFCLLLLYGWSITPLMYPASHFFSVSSTAYIVLISINLFVGINCTLATFILELFED-DKELTDINTVLKSVFLVFPNYCLGRGLIDLAKNQFLGIFSRFGVNLTR-----DPFSWDITGRNIFAMIIEGFVFFTLTVLIEY----RFFIKLRPVKVVLKPVEE-EDDDVQRERQRVNSGLGHATDALRLMNLTKVY 1332

HSP 2 Score: 55.8398 bits (133), Expect = 8.396e-8
Identity = 38/126 (30.16%), Postives = 61/126 (48.41%), Query Frame = 2

Query:    5 DRIAIISQGKLQCCGSSVFLKRKFGDGYRLIL-VKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            +R+AI+  G+++C GS   LK KFGDGY +IL V   N   E           ++ QFI    P+A ++ +      + +P         S LF +L+      +   Y ++ T+L++VFI  A D
Sbjct: 1525 NRVAIMVNGQMKCLGSPQHLKNKFGDGYTVILRVAGSNPDTE-----------QVCQFIIQCFPNAVLKDKHHNMVEYQIP---CQGLSVSRLFGHLEANRKMFDIEDYSVTQTTLDQVFINFAKD 1636

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Match: EDO38879 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBQ0])

HSP 1 Score: 291.582 bits (745), Expect = 3.739e-83
Identity = 260/891 (29.18%), Postives = 416/891 (46.69%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNF----NAQKENFRKGISN-------SGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE-----ETKNEKLI----------PDNLNRI-------------------AVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRN---------HKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESL------PAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSIN-PLTDRLESEYRSDLGESGIRCMNPSIYRST-------------HYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTG-YQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKF---LDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKYDA----FDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIK--------KTEDFDISLEKNRMNSEQKFDDVLQVINLTKIY 2404
             DRIAIIS GKL+C GS ++LKR+FG+GY L LVK      +    +FR+  S+       S +KL  FI SHI  A+++ +T  +++F+LP N      F  LF +L++ ID L   SYG++ T LEEVF++V D    +NE       + +KL           P +L  +                    V    E+ E  L  + L+       +L +   N +            L G  L  QQ   L +KRFHYA+RN KG+ ++++LP L I + + +   + P   L      P+M   P  +   + +  +N   ++  Q   ++++ +G    +  P  D L S  +  L +S +  M     R               H   +  Y N+  +   +       P C C+  G + +C+   +G  P     +T  D L N+TG N+S+YLL          YG   F                     +  FV         S L+S+  ID +++      I+ + ++ W N+KGY ++P Y N+ +N +LR+ + KS      YGI+  N P     ++      D + Q   ++ +AIFVI  +SF+PASFV+FLV ER + +K  QFVSG++P VYW+SN+LWD+  Y+IP +  I +   F   +Y    N  A + L + YG +I P MYP +F  S  S+A+V +   NL VG   T++TFIL +  D DE     N+++K + L FP Y LGRG++DL+ N           + D+    F+W + S  L  +++              G    +L  +++  +F  + +        +TED D++ E++R+      DD++++ NLTKIY
Sbjct:  801 GDRIAIISSGKLRCVGSPLYLKRRFGEGYNLTLVKKSISSPHGSIGSFRRSTSSNLEASRRSEEKLTSFITSHISSAQLKHKTNQEFTFILPDNSIKRGAFKKLFADLEQNIDVLGIDSYGITHTLLEEVFLKVTD--VSLNETGNMPHHRQDKLPTQLLQFPADKPGHLGHVLLSPPLPTLPTNEGLEMSDVVRNRGEDTERLLGYQPLSDSGTHQGNLYNEASNGHAAGLFEGVGSHTLTGSALQWQQFYALMLKRFHYARRNFKGVISQILLPALFICIAMTMALSLPPKPDLPPLELSPSMFYQPNYIPFGNEAKGMNILAKRLEQ-TLTLSSGIGATCCLRYPQYDLLNSTVK--LTKSQVALMFDKSCRKAIDEVSGVYLKPNKHRFSYIYYTNSSMNVSESVTHQKAGPGCRCSANGTWYLCDQGAAGKQPKELVTITR-DTLQNVTGRNMSEYLLYTTQTFRMHRYGALSF-------------------GNVVQFV--------PSRLDSVH-IDAVRRL----AIREA-SKSWYNNKGYHALPTYLNVMNNAILRASIPKSKGNPAAYGITAYNHPFPFNSTSAVHLSADYLRQGT-DLVIAIFVIIAMSFVPASFVVFLVTERSTKAKHLQFVSGVDPVVYWLSNYLWDMCNYLIPALACITLLYLFGVPAYASETNFPAVVGLFMLYGWSITPMMYPSAFCFSEASSAYVAMIVLNLFVGVTATVTTFILQLFPD-DEVLTDVNDVIKLISLGFPNYCLGRGLMDLAYNQYLSEYYRQIGEEDSIKSPFEWMIVSRNLVCMLM-------------EGFAFFILTILIEFKFFLKRRRIPVSQLPIETEDEDVAAERDRVLRGDADDDLVKIENLTKIY 1637

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Match: EDO48951 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI12])

HSP 1 Score: 102.449 bits (254), Expect = 3.356e-22
Identity = 70/209 (33.49%), Postives = 116/209 (55.50%), Query Frame = 2

Query: 1505 DYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITT----MSTFILDI--IEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNY 2113
            + GI  +N P+      K  D V   I  + LAIF+  G++F+ ASF+ FLV+ER S +K  QFVSG++ + YW + + WD + Y++P ++I+I+F AF  + +    +  +  LLLI +GL ++P +Y  SF   +   A+    A  + V SI +    ++ F+  I  +   DE      EI+  VF++ P Y +   +ID+S+NY
Sbjct: 1119 EQGIETTNHPLPNNAQNK-ADNVTSTISVLFLAIFMSMGMAFMAASFITFLVQERTSKAKHLQFVSGVDAFSYWSATYTWDFLNYLVPCLLILILFAAFQIEEF--ENDMGSVFLLLILFGLVVLPFIYVMSFAFKSQLIAY----AMTVFVLSIMSFGMLLAVFLCRIPSLNLLDEA-----EIMHYVFMLLPTYTVSYALIDMSTNY 1315

HSP 2 Score: 95.5153 bits (236), Expect = 5.028e-20
Identity = 68/222 (30.63%), Postives = 108/222 (48.65%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNR----NHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAE 655
             DRIAI++ G+L+CCGSS+FLK ++G GY L LVK  +              + ++  ++  +P A++ +    +  FVL  N   S  F  LFV L+   ++    SYG+S T++EEVF++V +          +EK + D LN              L L  L+ Q+ +    I +   R    N+ L  GF L  Q    + +KRF  +KR+KK +  +
Sbjct:  699 GDRIAIMADGQLRCCGSSLFLKSRYGVGYHLTLVKKEDCDD-----------NAIINAVRETVPSAQVLSNVGAEIEFVL--NGEASKDFESLFVKLENNKEDYGIASYGVSCTTMEEVFMKVGEG---------SEKTVEDILN--------------LLLRILSSQSLLRYQNIKIKILRLLKSNYPLQTGFALQWQHYKAMLVKRFINSKRDKKSVVTQ 884

HSP 3 Score: 56.9954 bits (136), Expect = 3.141e-8
Identity = 39/124 (31.45%), Postives = 65/124 (52.42%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ +C GS+  LK +FG GY L+L      + E     +SN+     QF+ S  P A++        ++   Q +S    +S +F  L+    +LN + Y +S TSLE+VF+ +A +
Sbjct: 1612 RLAIMVNGQFKCVGSAQHLKSRFGMGYTLML------KVEARLVPVSNTE----QFVSSTFPGAQLLESHNGMLTY---QINSTELSWSRIFGELERNRASLNIVDYSVSQTSLEQVFLNLAKE 1722

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Match: EDO32071 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW57])

HSP 1 Score: 55.8398 bits (133), Expect = 2.766e-8
Identity = 37/124 (29.84%), Postives = 63/124 (50.81%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRL--ILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVA 373
            R+ I+ +G+L+C GS+  LK KFG GY L   L  +F +   +      +   +L+ F++   P+AK       +  + +P+  SN  K S  F  L+E   ++    Y  S ++LE+VF+  A
Sbjct:  184 RVGIMVKGQLKCLGSTQHLKSKFGSGYTLEIKLSPSFQSSDPDV-----DMQTQLVAFVEGLFPNAKRTESFGDRVIYKVPK--SNVSKLSSTFATLEEGKRSIGIEEYSFSQSTLEQVFLEFA 300

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Match: EDO28092 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7F9])

HSP 1 Score: 53.5286 bits (127), Expect = 4.536e-8
Identity = 37/117 (31.62%), Postives = 62/117 (52.99%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEV 358
            R+AI+  G+ +C GS+  LK +FG GY L+L      + E     +SN+ ++  QF+ S  P A++        ++   Q +S    +S +F  L+    +LN + Y +S TSLE+V
Sbjct:   76 RLAIMVNGQFKCVGSAQHLKSRFGMGYTLML------KVEARLVPVSNT-EQAQQFVSSTFPGAQLLESHNGMLTY---QINSTELSWSRIFGELERNRASLNIVDYSVSQTSLEQV 182

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Match: ENSORLT00000045391.1 (ATP-binding cassette sub-family A member 1-like [Source:NCBI gene;Acc:101164844])

HSP 1 Score: 348.977 bits (894), Expect = 3.270e-102
Identity = 267/872 (30.62%), Postives = 442/872 (50.69%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN----FNAQKENFRKGI---------------------------SNSGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE-ETKNEKLIPD-----------NLNRIAVYGDIENQEPFLD------LEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMN----PSIYRSTHYRCF--PEYKNNKWSPIPNGNIPLI--SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKT---FKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNR 2410
             DRIAIIS GK++CCGSS+FLK+ FG GY L LV++      AQ+     GI                           SN  D   + QF++ H+P+A        + +F+LP   +    F+ LF  LD+ +D L   SYG+SDT+LEE+F++VA+D     E     E ++ D           +++R        N +  L       +ED  + A V+         R   ++ G+ L++QQ + L IKRFH+A+R++KG+ A+++LP + + L +    +V      P++E+ PW+   ++      TFY          +N +    +++ + + L      D    G RCM     P +  S+    +  P    +      NGN  +   SP C C+T G  I    C     G P    R+  ++D L NLT  N++D+LLK +    +K YGG      S  G +S+++            +   +     +NL    + D +QK     K  G + +  ++W  +KG+ SM ++ ++ +N +LR  L +       YG+SVSN P+ + +    L  +     ++ ++I VIF +SFIPASFV+FL++ERVS +K  QFVSG+NP VYWV++F+WDI  Y+IP  +++ IFI F  ++Y+  +N  A ILLL+ YG AI P MYP SF  + PSTA+VVL   NL +G   +++TF++++ E  DE+    N I+K+V LIFP + LGRG++D++ N    N+   + +    D   W +  + L ++ +   + +   +     +I    +   ++S    + ++ ED D++ E+ R++  +  +DVL++ +LTK+Y R
Sbjct:  753 GDRIAIISHGKMRCCGSSIFLKKSFGSGYYLTLVRSGTEVMTAQRSGIISGIAEEKPTESDCPSSSSLDEDRGCQSSDNSNPTDLKHVTQFVRRHVPEAVFLESIGQEITFILPYARARDGTFATLFQELDKVMDKLGLTSYGVSDTTLEEIFLKVAEDTGVDKELSPTKEPVVKDYKKDSRESKRRSMSRFHGKAAKGNTKDELKKKLSNKVEDFKKSASVN--------GRGSVVITGWKLIRQQFLALFIKRFHHARRSRKGLIAQVVLPAIFVCLALVFSLIVPSFTDYPSLELQPWMYNSQT------TFY----------SNDMPEDANVSRVVETL-----VDNPGFGTRCMEGNPIPRLPCSSGASDWFSPSVDQSVADIFLNGNWSMSNPSPSCQCSTPGRTIIMPDCPPGAGGLP-PPQRVQNTTDTLLNLTSINMTDFLLKTYEHSGKKRYGGI-----SVGGINSQVL------------LTEVEIEEAFANLEPPGYGDTIQKAEMVLKKLGTRNN-VKVWFYNKGWHSMVSFLSVVNNGILRGYLPEGQ-NLRQYGLSVSNHPLNLSKEQLSLSAMASTSSDVVVSICVIFAMSFIPASFVLFLIQERVSKAKHLQFVSGVNPTVYWVASFVWDICNYVIPCFLVVGIFICFQQKAYVSPQNLPALILLLVMYGWAITPMMYPASFIFTVPSTAYVVLTCLNLFIGINGSVATFVMELFE--DESITKINNIVKQVLLIFPHFCLGRGLMDMARNQAMANVFSNFGEDRFEDPLSWNMVGKNLIAMSIQGAVMFAFTL-----LIQYKFFYKPRLSLPKVQSEEKEDVDVARERQRVHEGRANNDVLRICDLTKVYPR 1568

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Match: ENSORLT00000046301.1 (ATP-binding cassette sub-family A member 1-like [Source:NCBI gene;Acc:101164844])

HSP 1 Score: 348.591 bits (893), Expect = 4.183e-102
Identity = 267/872 (30.62%), Postives = 442/872 (50.69%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKN----FNAQKENFRKGI---------------------------SNSGD--KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE-ETKNEKLIPD-----------NLNRIAVYGDIENQEPFLD------LEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMN----PSIYRSTHYRCF--PEYKNNKWSPIPNGNIPLI--SPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKT---FKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNR 2410
             DRIAIIS GK++CCGSS+FLK+ FG GY L LV++      AQ+     GI                           SN  D   + QF++ H+P+A        + +F+LP   +    F+ LF  LD+ +D L   SYG+SDT+LEE+F++VA+D     E     E ++ D           +++R        N +  L       +ED  + A V+         R   ++ G+ L++QQ + L IKRFH+A+R++KG+ A+++LP + + L +    +V      P++E+ PW+   ++      TFY          +N +    +++ + + L      D    G RCM     P +  S+    +  P    +      NGN  +   SP C C+T G  I    C     G P    R+  ++D L NLT  N++D+LLK +    +K YGG      S  G +S+++            +   +     +NL    + D +QK     K  G + +  ++W  +KG+ SM ++ ++ +N +LR  L +       YG+SVSN P+ + +    L  +     ++ ++I VIF +SFIPASFV+FL++ERVS +K  QFVSG+NP VYWV++F+WDI  Y+IP  +++ IFI F  ++Y+  +N  A ILLL+ YG AI P MYP SF  + PSTA+VVL   NL +G   +++TF++++ E  DE+    N I+K+V LIFP + LGRG++D++ N    N+   + +    D   W +  + L ++ +   + +   +     +I    +   ++S    + ++ ED D++ E+ R++  +  +DVL++ +LTK+Y R
Sbjct:  753 GDRIAIISHGKMRCCGSSIFLKKSFGSGYYLTLVRSGTEVMTAQRSGIISGIAEEKPTESDCPSSSSLDEDRGCQSSDNSNPTDLKHVTQFVRRHVPEAVFLESIGQEITFILPYARARDGTFATLFQELDKVMDKLGLTSYGVSDTTLEEIFLKVAEDTGVDKELSPTKEPVVKDYKKDSRESKRRSMSRFHGKAAKGNTKDELKKKLSNKVEDFKKSASVN--------GRGSVVITGWKLIRQQFLALFIKRFHHARRSRKGLIAQVVLPAIFVCLALVFSLIVPSFTDYPSLELQPWMYNSQT------TFY----------SNDMPEDANVSRVVETL-----VDNPGFGTRCMEGNPIPRLPCSSGASDWFSPSVDQSVADIFLNGNWSMSNPSPSCQCSTPGRTIIMPDCPPGAGGLP-PPQRVQNTTDTLLNLTSINMTDFLLKTYEHSGKKRYGGI-----SVGGINSQVL------------LTEVEIEEAFANLEPPGYGDTIQKAEMVLKKLGTRNN-VKVWFYNKGWHSMVSFLSVVNNGILRGYLPEGQ-NLRQYGLSVSNHPLNLSKEQLSLSAMASTSSDVVVSICVIFAMSFIPASFVLFLIQERVSKAKHLQFVSGVNPTVYWVASFVWDICNYVIPCFLVVGIFICFQQKAYVSPQNLPALILLLVMYGWAITPMMYPASFIFTVPSTAYVVLTCLNLFIGINGSVATFVMELFE--DESITKINNIVKQVLLIFPHFCLGRGLMDMARNQAMANVFSNFGEDRFEDPLSWNMVGKNLIAMSIQGAVMFAFTL-----LIQYKFFYKPRLSLPKVQSEEKEDVDVARERQRVHEGRANNDVLRICDLTKVYPR 1568

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BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Match: zgc:172302 (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101162276])

HSP 1 Score: 316.62 bits (810), Expect = 3.963e-91
Identity = 273/912 (29.93%), Postives = 433/912 (47.48%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK------------------------------NFNAQKENFRKGISNSGD---KLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPS--------IYRSTHYRCFPEYKNNKWSPIPNGNIP--LISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKL-----------YGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHN---QSNLNSL--KFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK------YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNN----------KIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLCF 2500
             DRIAIIS+GKL CCGS +FLK + G GY L +VK                              + ++  E+   G   S      LL  ++ HIP A +  E+  +    LPQ  +     +     LD+ +  L   SYGLSD++LEE+F+RVA++   ++ E + E+L P   N     G+   ++P     +  +   ++  L+S +  R  + L G  L+ QQ+  L IKR+ YA+R+++G FA+++LP L + + +    +V P    P++E+ PW+   +       TF+  +   N ++ N L               E   D    G +CM           +     +R  P+   + W     GN      SPEC C+T         C +   G PP   + +T  D L NLT YN+SDYL+K + ++ +K            YGGF            K+       E + D V+A +  +     S+L+SL  K   +L+       +K     +W N+KG+ SM ++ N+ +N LLR+ L     +   +GIS  N P+ + +       +    +++ ++  VIF +SF+PASFV+FL+EER S +K  QFVSG+ P +YWV+NF+WD++ Y +P  ++++IFI F  +SY+  +N  A ILLL+FYG +I P MYP SF  + PSTA+VVL + NL +G   +M+TF+L++    D+     N +LKKVFLIFP + LGRG+ID++ N     M D + +       D F W+   + L  +                GV   +   +L+  +F +               ED D++ E+ R+ S +   D+L +INL+K+Y                      +K AVN LC 
Sbjct: 1127 GDRIAIISKGKLCCCGSPLFLKSQLGSGYYLTVVKREETNPNTPSGSSFSTSTSIITNKLPHAKDSESSLSEDTGLGSDESSSCVAALLALVQQHIPSASLVEESRREAVINLPQKAAKDGSLAIFLSKLDQRLPELGISSYGLSDSTLEEIFLRVAEE-TGVDAEPEQEELSP---NSQQPSGERVEEQP----AEQPEPEPLETDLLSGDC-RGGEPLSGSWLMWQQLKALFIKRWLYARRSRRGFFAQIVLPALFVLVALLFSLIVPPFGRYPSVELQPWMYGEQY------TFFSNDAPGNPAMENLL---------------EALLDQPGFGTKCMEKEEGNNTSCEVEGGGQFR-RPQVSFSMWQMFSKGNWSKERPSPECQCSTEDVSRMLPECPEGAGGLPPPQIKRVTG-DILQNLTSYNVSDYLVKTYAQILKKSLKTKKLVNEFRYGGFSL--------GGKVTQTEVDVEHVEDAVSAFRRRYQVTQNSSLDSLLNKLPAFLEGLHSKDNVK-----VWFNNKGWHSMVSFVNVMNNGLLRASLPPGPER-SKHGISAYNHPLNLTKDQLTEVALMATSVDVLISTCVIFAMSFVPASFVLFLIEERASKAKHLQFVSGVQPLLYWVANFIWDMLNYAVPAAMVVLIFIGFQQKSYVSEQNLPALILLLLFYGWSITPLMYPASFVFTVPSTAYVVLTSINLFIGINCSMATFVLELF--VDDNLNQINNVLKKVFLIFPHFCLGRGLIDMAKNQA---MADAFHRLGARPVLDPFQWDFVGKNLFCMAAS-------------GVFYFIFTILLQYKFFIHLKPWWTEPQLPPIGPEDEDVARERARVMSGKFHSDILTMINLSKVY-------------------KAGKKPAVNRLCL 1955

HSP 2 Score: 54.299 bits (129), Expect = 6.558e-7
Identity = 34/125 (27.20%), Postives = 62/125 (49.60%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLIL-VKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ QC GS   LK +FGDGY +IL + +  +  E+           + +++    P+ +++ +      + LP   S+ C  + +F  L    + L    + +S T+L++VFI  A D
Sbjct: 2134 RMAIMVNGQFQCLGSVQHLKNRFGDGYTVILRLADTKSDTESC---------PVDEYMTKSFPNIELKEQHQNVLQYHLP---SHGCSLALIFDALANNCEELGVADFSVSQTTLDQVFISFAKD 2246

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Match: ENSORLT00000025407.2 (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163308])

HSP 1 Score: 302.753 bits (774), Expect = 1.831e-86
Identity = 272/927 (29.34%), Postives = 444/927 (47.90%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-----------------NFNAQ-KENFRKGISNSG----------------------------DKLL--QFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFL-----DLEDLNQQA----FVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNP-SIYRST--------HYRCFPEYKNNKWSPIPNGNIPL--ISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQF------VLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLK-FIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERG--VINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLC 2497
             DRIAIIS GKL C GSS++LK + G GY L LVK                 +FN + +EN     S++G                            D  L    I  H+P A++  +   + +++LP + + +  F  LF +LD ++  L   SYG+SDT+LEE+F++VA+D     E   +  L      R   +G  E+Q         D  D N         +   +S    +    + G+ L +QQ + L  KRF YA+R++KG FA+++LP + + + +    +V P    P++E+ PW+                E+Q+ F   +  G+ N    L   +E          G RCM+  SI  S         H    PE     +S   +GN  +   SP C C + G +     C     G PP   + ++++D L NLTG NISDYL+K + ++  K            YGGF        VLP      +  I D+   E +R+     +       L+SL  FI+ L     +        ++W N+KG+ S+PA+ N+ +N +LR+ L   A    +YGI   N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERV+ +K  QF+SG+ P +YW +NFLWD+  Y +P  ++I+IF+ F  ++Y+ S N     LLL+ YG +I P MYP SFF + PSTA+VVL + N+L+G   ++STF++++  D +      N+ILK V LIFP + LGRG+ID+  N    +  + + +       +W++  + L ++ +  ++++II ++I+    +  R + ++ K+          ED D++ E+ R+       D+L++  LTK++ R                    QK AV+ LC
Sbjct: 1104 GDRIAIISHGKLCCVGSSLYLKNQLGSGYYLTLVKKDPETSLSSCRNSSSTISFNKKDEENTSVSSSDAGLGSEHESEAATIENGPAASICTVPFVPTDTSLVSALILRHVPTARLVEDLGHELTYILPYSAAKNGAFVELFKDLDLKLHELGISSYGVSDTTLEEIFLKVAEDNGVDTEVLSDGTLPVRARRRTHAFGGGEHQSCLKPISEDDTYDCNDSEGDPDCRETDWLSCTEGKGSYQVNGWSLRRQQFVALMWKRFLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLELQPWMY---------------EDQVTFISDDAPGDANMQKLLKSLMEPP------GFGTRCMDGYSIPESPCTMGDEDWHNPDVPESLQQLFS---SGNWTMENPSPSCFCASDGKKRMLPDCPVGAGGLPPPEMK-LSATDTLQNLTGRNISDYLVKTYAQIIGKSLNNKVWVNEFRYGGFSLGARSTQVLPP-----ANEIDDA--IERVRNIFELQKGAAADRFLDSLSNFINGLDTKNNV--------KVWFNNKGWHSVPAFMNVMNNAILRANLPPGADPS-NYGIMSFNHPLNLTKEQLSQVALVTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPLLYWTANFLWDMCNYFVPAALVILIFVCFQQKAYVSSANLPVLALLLLLYGWSITPLMYPASFFFTIPSTAYVVLTSVNILIGINGSISTFVMELFGDHE--IGGINDILKNVLLIFPHFCLGRGLIDMVKNQAMADALERFGENRFRSPLEWDMVGKNLFAMAVEGVVFFIITLLIQYKFCIKPRPISKLTKMGSLGE-----EDEDVARERQRIVQGLGQGDILELRQLTKVFKR-------------------KQKPAVDRLC 1963

HSP 2 Score: 50.8322 bits (120), Expect = 6.480e-6
Identity = 34/124 (27.42%), Postives = 60/124 (48.39%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ +C GS   LK +FGDGY +IL             G       +++FI+S +  + ++ +      + LP   S+    + +F  L +  D L    Y ++ T+L++VF+  A D
Sbjct: 2143 RMAIMVNGRFRCLGSVQHLKNRFGDGYTIILRV----------AGPDPDLLPVMKFIESELSGSTLKEKHRNMLQYQLP---SSLTSLAHIFSILAKNKDTLRIEDYSVTQTTLDQVFVNFAKD 2253

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Match: abca1a (ATP-binding cassette sub-family A member 1 [Source:NCBI gene;Acc:101163147])

HSP 1 Score: 301.212 bits (770), Expect = 6.792e-86
Identity = 262/900 (29.11%), Postives = 430/900 (47.78%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVK-NFNAQKENFR------------------------KGISNSGDK---------LLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIEN-QEPFLDLE-DLN-QQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCM------NPSIYRSTHYRCFPEYKNNKWSPIPNGNIPL--ISPECDCNTTGYQI----CNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRK-----------LYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIF--XXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAK---YDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRML---KVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLC 2497
             DRIAIIS GKL C GSS+FLK   G GY L +VK +++   ++ R                         G+ +  D          +   I  H+ +A++  +   + ++VLP   +    F  LF  LD+ + +L   SYG+SDT+LEE+F++VA+D + ++    ++ ++P    R   +GD ++  +PF + E D N  +   +   +     +    ++G+ L +QQ + L  KRF YA+R++KG FA+++LP + + + +    +V P    P++ + P             + Y +  Q +F I+N + +    +P T++L        G  G RCM      N            PE   +       GN      SP C C+  G +     C D   G PP   RI +  D L NLTG N+SDYL+K + ++  K            YGGF     S+   S K   D    +  R F       H +    + +F   L    +    K +  +IW N+KG+ S+ ++ N+     L       K   KF   GI+  N P+ + +       +    +++ ++I VIF +SF+PASFV+FL++ERV+ +K  QF+SG+ P++YW++NF+WD+  YI+P  ++IIIF+ F   +Y+ S N     LLL+ YG +I P MYP SFF   PSTA+VVL + N+L+G   ++STF+L++    +      N+ILK VFLIFP + LGRG+ID+  N    +  + + +        W++  + L ++ +  ++++         +   + YR     + S  + K    ED D++ E+ R+ S     D+L++  LTKIY R                    QK AV+ LC
Sbjct: 1102 GDRIAIISHGKLCCVGSSLFLKTHLGTGYYLTMVKRDYDLALQSCRNSASTVSYSKKTEKEDSISESSSDAGLGSEPDSETTTIDVSLISNVIFKHVREARLVEDLGHELTYVLPYQSAKDGAFVELFHELDDRLTDLGISSYGISDTTLEEIFLKVAED-SGVDAVELSDGVVPTRTRRRHAFGDHQSCLKPFTEDEFDFNDSEESRETDWLGGADGKGSFQVKGWSLKRQQFVALLWKRFLYARRSRKGFFAQIVLPAVFVCIALVFSLIVPPFGKYPSLALHP-------------SMYGE--QFSF-ISNDMPD----DPHTNKLLGALMEKPG-FGSRCMKGEPIPNTPCTAVEDEWAVPEVSESLRDIFAKGNWTRENPSPLCQCSCEGRKRMLPECPDGAGGLPPPQMRI-SDKDTLQNLTGRNVSDYLVKTYAQIIGKSLKNKIWVNEFRYGGFSLGARSSQFLSHKDDIDVAIAQLRRRF-------HLERGTAADRFFHSLSSFIQGLDSKNN-VKIWFNNKGWHSISSFLNVMNNGILRASLPAGKDPTKF---GITAYNHPLNLTKEQLSQVALMTTSVDVLVSICVIFAMSFVPASFVVFLIQERVNKAKHMQFISGVQPFLYWLANFVWDMCNYIVPATLVIIIFVCFQQDAYVSSTNLPVLALLLLLYGWSITPLMYPASFFFKIPSTAYVVLTSVNILIGINGSVSTFVLELFGSNE--IGGINDILKNVFLIFPHFCLGRGLIDMVKNQAMADALERFGENRFRSPLAWDMVGKNLFAMAVEGVVFFC--------ITVLIQYRFCITTRSSISHLKPIGEEDEDVARERQRVLSGSGQSDILELRELTKIYKR-------------------KQKPAVDRLC 1938

HSP 2 Score: 51.9878 bits (123), Expect = 3.233e-6
Identity = 34/124 (27.42%), Postives = 60/124 (48.39%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADD 379
            R+AI+  G+ +C GS   LK +FGDGY +IL         + R         ++ FI+  +P + ++ +      + LP   S+    + +F  L +  + L    Y +S T+L++VF+  A D
Sbjct: 2118 RMAIMVNGRFRCLGSVQHLKNRFGDGYTIIL--RVAGPDPDLR--------PVMGFIERELPGSTLKEKHRNMLQYQLP---SSLTSLARIFSLLSKNKETLCIEDYSVSQTTLDQVFVNFAKD 2228

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Match: SMESG000029534.1 (SMESG000029534.1)

HSP 1 Score: 1401.34 bits (3626), Expect = 0.000e+0
Identity = 746/835 (89.34%), Postives = 782/835 (93.65%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKYDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNN-KIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCC-KNKNNDVENENQKFAVNNLCF 2500
            SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAELILPILMITLMIALLKLVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNF KLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIW NSKGYVSMPAYANIFSNLLLRSRLNKSAVKFIDYGISVSNFPIEMEQSTKFLDLV QMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYIIPIIIIIIIFIAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLN YNLLVG+ITT+STFILDI+E   E  +  N+ILKKVFLIFPQ++LGRG++DL  NY   + +    +Y+A  W++A EKL SL  L + WWI+LIIIE G++NR++   LK SY    +I+ TEDFD++LE+ RM+S+QK DDVL+VINLTKIYN    F+  C  K K+N ++N+ ++ AVNNLCF
Sbjct:  947 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAELILPILMITLMIALLKLVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFRKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWVNSKGYVSMPAYANIFSNLLLRSRLNKSAVKFIDYGISVSNFPIEMEQSTKFLDLVIQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYIIPIIIIIIIFIAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNVYNLLVGTITTISTFILDILEGNYEYLKEINDILKKVFLIFPQFNLGRGIMDLFFNYFYNSNSIVKHEYNALQWDIAGEKLFSLFSLSIGWWIVLIIIESGIVNRIICGKLKNSYLKRIEIRNTEDFDVNLERERMSSDQKSDDVLRVINLTKIYNVYLKFKDNCGEKGKDNYIKNKAREVAVNNLCF 1781

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Match: SMESG000029537.1 (SMESG000029537.1)

HSP 1 Score: 1023.85 bits (2646), Expect = 0.000e+0
Identity = 585/836 (69.98%), Postives = 669/836 (80.02%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPA-KINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLE-DLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXX-XXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKYDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLCF 2500
            SDR+AIISQGKLQCCGS VFLKRKFG+GY L L+KN N    + R     +G+ +L+F+K +I DA+M  E+  QW+ VLPQND NS KF+ LF NLD+ +  ++ +SYGLSDTSLEEVF++VADDP  K+  + K+      N+ ++ +  +    E FL+   D  Q  F+D+S        +H LL+GFPLL+QQII L IKR+HYAKR+ KG  AELIL  ++++ +++ L   + P + +P M+ISPWLMM K    NLNTFYRKEN         LG       L ++LESEYRSDLGESGIRCMNPSIYR  +Y+CF   +NN WSP    +IP++SPECDC+ TG QICND RSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNF +LSRK++GG+QF+LP+ F  SSKLI  SP W+ +RD VN SQ      NL  L+F+ Y Q+ F       +F+RIW NSKGY SMPAYANI SNLLLRSR+  S   + +YGISV+N+PI  +  TK     N ++LE++LAI+VI  LSFI ASFVIFL++ER+SGSKRQQFVSGINPYVYWVSNFLWDIMKYIIPIIIIIIIFIAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKYDAFDWEVASEKLASLILLFLLWWIILIIIERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLCF
Sbjct:  899 SDRVAIISQGKLQCCGSLVFLKRKFGEGYYLSLLKNQNNHSNSNR-----NGENILKFVKIYIADARMMEESRLQWTIVLPQNDINSRKFTELFKNLDQHMAEMSIISYGLSDTSLEEVFLKVADDPMNKLINKEKSYYSYYCNILKMKLRINATKTEIFLNQNPDQKQSKFLDQS--------DH-LLKGFPLLQQQIIALHIKRYHYAKRDFKGFLAELILPVLMILFIILFLKISILPKKQIP-MQISPWLMMSKMGKENLNTFYRKENI-------SLG-------LINKLESEYRSDLGESGIRCMNPSIYRLDNYQCFYRNENNMWSPASILDIPMVSPECDCSKTGNQICNDLRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFQRLSRKIFGGYQFLLPNDFAQSSKLIAQSPTWDGIRDSVNQSQPQ----NLEPLRFLKYFQEFFNKSSKTMNFSRIWINSKGYASMPAYANILSNLLLRSRIKLSQNSW-NYGISVTNYPIA-DSETKISQFNNLILLEVTLAIYVILALSFISASFVIFLIDERISGSKRQQFVSGINPYVYWVSNFLWDIMKYIIPIIIIIIIFIAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKYDAFDWEVASEKLASLILLFLLWWIILIIIERGVINRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNNDVENENQKFAVNNLCF 1699

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Match: SMESG000032861.1 (SMESG000032861.1)

HSP 1 Score: 851.277 bits (2198), Expect = 0.000e+0
Identity = 485/837 (57.95%), Postives = 615/837 (73.48%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQ-QAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKYDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKT--EDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNND-VENENQKFAVNNLCF 2500
            SDRIAIISQGKLQCCGSSVFLK++FGDGY LILVKN  +Q+E+FR GIS+SG+K+L FI++HI DAKM  ET TQW+ VLPQN+ NS KFS LF ++D  +  LN +SYGLSDTSLEEVF++VADDPA   EE K++++  ++L+ +   G+       L      +   F D + I         LL G  LL+QQ++GLQ+KRFHY KRN KG  AEL+LPIL+I +MIA  K+ + L   P MEISPWLMMPK+RS+NLNTFYRKEN              S N L D+L   YRSDL E+G RCMN S+YR   Y C      N+W+  P   IPL++  CDCNTTG+Q+C++  SGGP NSYR+M S+DKLNNLTGYNISD+L+K F    +K YGGFQF+LPS FG S KLIG  P W+ +R   + S ++++ SN + L F++Y Q+ F + GIKT+FTRIW NSKGY S+PAY NIFSNLL+R+R   +     +YGISV+N+P++  QS     L  QM +E+SLA+FVIFGLSFIPASFVIFL+EER++GSKRQQ VSG+NPYVYW+SNFLWDI+KYI+PI II++IF+AFDYQSYIGSKN  AFI LLIFYGLAIIPHMYPFSF +STPSTAFVVL+AYNLL+GSITT+STF LD+++  DET +P N++LKKVFL+FPQY LGRGM+DLS NY+ +N+++G   YD F W    EKL SL +LF+ WWI++ IIE G+INR+L   +K      K  K   ED D+++E+ R+ SE+  DDVL+VI LTK+YN++ N ++ CCK    D +ENE +K AVNNLCF
Sbjct:  883 SDRIAIISQGKLQCCGSSVFLKKEFGDGYYLILVKNSRSQEEDFRSGISSSGEKVLNFIRAHITDAKMIEETRTQWTIVLPQNEINSGKFSDLFADIDRSLSGLNIVSYGLSDTSLEEVFLKVADDPAGTVEEIKDKQITAEDLDSLTDDGNFPRPSSRLSFRCKREFPRFDDLNSIPYESGAPSSLLTGSALLRQQLLGLQVKRFHYTKRNIKGFVAELVLPILLIVVMIAFSKISSNLNYQPPMEISPWLMMPKARSLNLNTFYRKEN--------------SSNTLIDKLVEGYRSDLSEAGTRCMNQSVYRLDSYPCSSSI-GNQWTGNPPEPIPLLTAACDCNTTGFQLCSNSSSGGPQNSYRLMASTDKLNNLTGYNISDHLIKKFKSYIKKQYGGFQFLLPSPFGQSCKLIGSLPIWDAMR---SQSNSSNSSSNSDQLPFLNYFQEFFNLSGIKTNFTRIWINSKGYASLPAYGNIFSNLLMRTRFESNGS---NYGISVANYPLKYTQSDLLSKLNTQMFVEVSLAVFVIFGLSFIPASFVIFLIEERITGSKRQQIVSGVNPYVYWMSNFLWDILKYIVPIFIIVLIFVAFDYQSYIGSKNLGAFITLLIFYGLAIIPHMYPFSFLLSTPSTAFVVLDAYNLLLGSITTISTFFLDLLQQDDETLKPVNDVLKKVFLLFPQYGLGRGMMDLSFNYLTFNISNGKQDYDPFGWSTTGEKLCSLSVLFVGWWIVVFIIESGIINRMLCGKIKNRNLKAKEMKDEFEDVDVAVERERIISEKISDDVLKVIKLTKVYNQSLNVKNTCCKKVVKDTLENEKRKLAVNNLCF 1698

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Match: SMESG000032891.1 (SMESG000032891.1)

HSP 1 Score: 846.269 bits (2185), Expect = 0.000e+0
Identity = 484/837 (57.83%), Postives = 612/837 (73.12%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQ-QAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKYDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINRVLYRMLKVSYFNNKIKKT--EDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNND-VENENQKFAVNNLCF 2500
            SDRIAIISQGKLQCCGSSVFLK++FGDGY LILVKN  +Q+E+FR GIS+SG+K+L FI++HI DAKM  ET TQW+ VL QN+ N+ KFS LF ++D  +  LN +SYGLSDTSLEEVF++VADDPA   EE K++++  ++L+ +   G+       L   D  +   F D + I         LL G  LL QQ++GLQ+KRFHY KRN KG  AEL+LPIL+I +MIA  K+ + L   P MEISPWLMMPK+RS+NLNTFYRKEN              S N L D+L   YRSDL E+G RCMN S+YR   Y C      N+W+  P   IPL++  CDC  TGYQ+C++  SGGP NSYR+M S+DKLNNLTGYNISD+L+K F    +K YGG+QF+LPS FG S KLIG  P W+ +R   + S ++++ SN + L F++Y Q+ F + GIKT+FTRIW NSKGY S+PAY NIFSNLLLR+R   +     +YGISV+N+P++  QS     L  QM +E+SLA+FVIFGLSFIPASFVIFL+EER++GSKRQQ VSG+NPYVYW+SNFLWDI+KYI+PI II++IF+AFDYQSYIGSKN  AFI LLIFYGLAIIPHMYPFSF +STPSTAFVVL+AYNLLVGSITT+STF LD+++  DET +P N++LKKVFL+FPQY LGRGM+DLS NY+ +N+++G   YD F W    EKL SL +LF+ WWI+++IIE G+INR L   +K      K  K   ED D+++E+ R+ SE+  DDVL+VI LTK+YN++ N ++ CCK    D +ENE +K AVNNLCF
Sbjct:  873 SDRIAIISQGKLQCCGSSVFLKKEFGDGYYLILVKNSRSQEEDFRSGISSSGEKVLNFIRAHITDAKMIEETRTQWTIVLSQNEINNGKFSDLFADIDRSLSGLNIVSYGLSDTSLEEVFLKVADDPAGTVEEIKDKQITTEDLDSLTDDGNFPRPSSRLSFRDKREFPRFDDLNSIPYESGAPSSLLTGSALLCQQLLGLQVKRFHYTKRNIKGFVAELVLPILLIVIMIAFSKISSNLNYQPPMEISPWLMMPKARSLNLNTFYRKEN--------------SSNTLIDKLVEGYRSDLSEAGTRCMNQSVYRLDSYPC-SSRTGNQWTGNPPEPIPLLTAACDCKKTGYQMCSNSSSGGPQNSYRLMASTDKLNNLTGYNISDHLIKKFKSYIKKQYGGYQFLLPSPFGQSCKLIGSLPIWDAIR---SQSNSSNSSSNSDQLPFLNYFQEFFNLSGIKTNFTRIWINSKGYASLPAYGNIFSNLLLRTRFESNGS---NYGISVANYPLKYTQSDLLSKLNTQMFIEVSLAVFVIFGLSFIPASFVIFLIEERITGSKRQQIVSGVNPYVYWMSNFLWDILKYIVPIFIIVLIFVAFDYQSYIGSKNLGAFITLLIFYGLAIIPHMYPFSFLLSTPSTAFVVLDAYNLLVGSITTISTFFLDLLQKDDETLKPVNDVLKKVFLLFPQYGLGRGMMDLSFNYLTFNISNGKQDYDPFGWSTTGEKLCSLSVLFVGWWIVVLIIESGIINRTLCGKIKNRNLKAKEIKDEFEDVDVAVERERIISEKISDDVLKVIKLTKVYNQSLNVKNTCCKKVVKDALENEKRKLAVNNLCF 1688

[Close]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Match: SMESG000068605.1 (SMESG000068605.1)

HSP 1 Score: 837.795 bits (2163), Expect = 0.000e+0
Identity = 461/836 (55.14%), Postives = 607/836 (72.61%), Query Frame = 2

Query:    2 SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVYGDIENQEPFLDLEDLNQQAFVDK-SLISLNFNRNHKLLRGFPLLKQQIIGLQIKRFHYAKRNKKGIFAEXXXXXXXXXXXXXXXXXVNPLESLPAMEISPWLMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDLGESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTGYQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYGGFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDYLQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFXXXXXXXXXXKSAVKFIDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVIFLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYXXXXXXXXXXXXAFDYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYNLLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDLSSNYIKYNMTDGYAKYDAFDWEVASEKLASXXXXXXXXXXXXXXXERGVINR-VLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKIYNRTFNFRSVCCKNKNND-VENENQKFAVNNLCF 2500
            SDRIAIISQGKLQCCGSSVFLK++FG+GY LI+VK  + Q E+F+  +S SG   L+FI++H+PDAKM  ET +QW+  LPQ+++N  KF  LF NLD  +++L  ++YGLSDTSLEEVF++VADDP+      K +KL P+ L+ +   G+       L L D ++ A +++   +S      + +L G  L  QQIIGLQIKRFHY +RN K   AEL+LP+LMI ++I LL + +PL   P M ISPWLMMPK+R +NLNTFYRKE+                N + D +E+ YRSD+GESG+RCMN ++YR  +Y C+PE   N+WS IP+  I L SPECDC+ TG+Q C+DP SGGP  S RIMTSSD+L N+TGYNISDYLLK F    +K YGG+QF+LPS FG SS  IG SP W+ +     +S  N + +N NSL F++Y Q+ F   GIKT++TRIW NSKG+VSMPAY NIFSN+LLRS+L  S      YGISV+N+P++  Q+     L  QM LE+SLAIFVIFGLSFIPASFVIFL+EER+SG+KRQQFVSG+NPY+YW+SNF+WD++KYIIP+ I+++IF+ F+YQSYIG++NA AFI+LL+FYGLAIIPHMYPFSF +S PSTAFV+L+AYNLLVG+ITT++TF LD+++  D + +P N++LKK+FLIFPQYDLGRGM+DLS NY++YN++ G   YD F WE   +KL SLI+LF+ WW ++  IE G+INR +  R+        +++  ED D+ LE+ RM   ++  DVL+VINLTKIYN + N  + CCK    D + +E +K AVNN+CF
Sbjct:  909 SDRIAIISQGKLQCCGSSVFLKKEFGNGYYLIIVKTESIQWEDFQNELSISGGIALKFIQNHVPDAKMMEETRSQWTIALPQSENNCSKFPDLFDNLDRAMEDLGIVTYGLSDTSLEEVFLKVADDPSGEVGGIKEKKLTPEKLDALTDGGNFPRPASILSLRDKSEFAKIEEIRRVSFKSEITYSMLTGISLFIQQIIGLQIKRFHYTRRNMKSFIAELVLPVLMILMIIGLLNISSPLSDAPPMVISPWLMMPKTRLVNLNTFYRKES--------------PSNAIIDSMENVYRSDVGESGVRCMNSAVYRLGNYSCYPENNVNQWSAIPSAPISLSSPECDCSKTGFQFCSDPLSGGPTISSRIMTSSDQLGNITGYNISDYLLKKFKTFIKKQYGGYQFLLPSNFGLSSNSIGSSPIWDGI-----SSYINSSPNNSNSLGFLNYSQRFFNQSGIKTNYTRIWVNSKGFVSMPAYENIFSNILLRSKL-NSFSDISKYGISVTNYPLKFSQTDLQSQLNTQMFLEVSLAIFVIFGLSFIPASFVIFLIEERISGAKRQQFVSGVNPYLYWISNFMWDLVKYIIPVAIVLVIFVLFNYQSYIGTQNAGAFIVLLLFYGLAIIPHMYPFSFVLSNPSTAFVILDAYNLLVGAITTIATFFLDLLQVDDPSLKPANDVLKKIFLIFPQYDLGRGMMDLSFNYLQYNISGGKVTYDPFGWETTGQKLCSLIILFIAWWSVIFTIESGIINRSICGRIKNYKLKERELQHEEDTDVFLERERMTKRKENVDVLKVINLTKIYNPSLNINNKCCKRAVADSLSSEKRKLAVNNICF 1724

HSP 2 Score: 50.0618 bits (118), Expect = 9.008e-6
Identity = 41/133 (30.83%), Postives = 61/133 (45.86%), Query Frame = 2

Query:    8 RIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISNSGDKLLQFIKSHIPDA---KMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEEIDNLNALSYGLSDTSLEEVFIRVADDPAKINE 397
            R++I+  G+++C G+   LK KFGD Y + +  NF          I N  DK+   +K+  P     K E     Q+ F      + S K S +F   +    N     Y +S TSL+EVFI  A + +  NE
Sbjct: 1904 RLSIMVNGEMKCLGNVQHLKSKFGDDYFVKIRMNF----------IENESDKIKAIMKTQFPQGVSLKDENFITLQYRF------NCSLKLSTIFHFFENLKANGVIADYSVSQTSLDEVFINFAKNKSSNNE 2020

The following BLAST results are available for this feature:

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Yeast
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ABCA1	1.355e-84	29.40	ATP binding cassette subfamily A member 1 [Source:...	[more]
ABCA7	6.480e-81	29.17	ATP binding cassette subfamily A member 7 [Source:...	[more]
ABCA4	3.604e-78	28.59	ATP binding cassette subfamily A member 4 [Source:...	[more]
ABCA4	1.724e-68	27.90	ATP binding cassette subfamily A member 4 [Source:...	[more]
ABCA12	9.307e-57	28.62	ATP binding cassette subfamily A member 12 [Source...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
abt-2	1.842e-18	25.85	ABC Transporter family [Source:UniProtKB/TrEMBL;A...	[more]
abt-2	1.948e-18	25.85	ABC Transporter family [Source:UniProtKB/TrEMBL;A...	[more]
abt-4	1.933e-14	29.82	ABC Transporter family [Source:UniProtKB/TrEMBL;A...	[more]
ced-7	7.817e-14	26.46	ABC transporter ced-7 [Source:UniProtKB/Swiss-Pro...	[more]
ced-7	8.310e-14	26.46	ABC transporter ced-7 [Source:UniProtKB/Swiss-Pro...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG34120	3.317e-18	28.07	gene:FBgn0083956 transcript:FBtr0343018	[more]
CG34120	3.484e-18	28.07	gene:FBgn0083956 transcript:FBtr0299591	[more]
CG34120	3.491e-18	28.07	gene:FBgn0083956 transcript:FBtr0110827	[more]
ABCA	3.672e-17	33.02	gene:FBgn0031170 transcript:FBtr0332488	[more]
ABCA	3.822e-17	33.02	gene:FBgn0031170 transcript:FBtr0332489	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
abca4a	2.138e-91	28.31	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
abca4b	1.293e-89	28.90	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
abca1b	4.785e-86	28.74	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
abca4b	1.590e-85	28.49	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
abca1b	1.282e-84	28.40	ATP-binding cassette, sub-family A (ABC1), member ...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ABCA1	7.709e-91	29.41	ATP binding cassette subfamily A member 1 [Source:...	[more]
ABCA1	1.145e-90	30.25	ATP binding cassette subfamily A member 1 [Source:...	[more]
ABCA1	2.162e-90	29.43	ATP binding cassette subfamily A member 1 [Source:...	[more]
klf9	1.048e-89	29.60	Kruppel-like factor 9 [Source:Xenbase;Acc:XB-GENE-...	[more]
ABCA1	2.701e-89	29.75	ATP binding cassette subfamily A member 1 [Source:...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Abca1	3.071e-84	29.24	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
Abca4	5.904e-84	27.99	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
Abca7	2.613e-76	27.98	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
Abca7	2.613e-76	27.98	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
Abca7	5.009e-76	28.20	ATP-binding cassette, sub-family A (ABC1), member ...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O95477\|ABCA1_HUMAN	6.509e-84	29.40	Phospholipid-transporting ATPase ABCA1 OS=Homo sap...	[more]
sp\|P41233\|ABCA1_MOUSE	2.148e-83	29.24	Phospholipid-transporting ATPase ABCA1 OS=Mus musc...	[more]
sp\|O35600\|ABCA4_MOUSE	4.130e-83	27.99	Retinal-specific phospholipid-transporting ATPase ...	[more]
sp\|Q8IZY2\|ABCA7_HUMAN	3.112e-80	29.17	Phospholipid-transporting ATPase ABCA7 OS=Homo sap...	[more]
sp\|P78363\|ABCA4_HUMAN	1.731e-77	28.59	Retinal-specific phospholipid-transporting ATPase ...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3JVH4	1.712e-120	32.07	LOW QUALITY PROTEIN: ATP-binding cassette sub-fami...	[more]
V4ABB8	1.086e-113	34.45	Uncharacterized protein OS=Lottia gigantea OX=2251...	[more]
N1PB02	3.158e-105	33.10	Uncharacterized protein OS=Capitella teleta OX=283...	[more]
A0A3P9HY39	2.464e-99	30.62	Uncharacterized protein OS=Oryzias latipes OX=8090...	[more]
A0A3P9HY72	2.684e-99	30.62	Uncharacterized protein OS=Oryzias latipes OX=8090...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
abca4a	6.324e-95	29.70	retinal-specific ATP-binding cassette transporter-...	[more]
ENSAMXT00000022236.2	1.522e-93	31.21	pep primary_assembly:Astyanax_mexicanus-2.0:21:133...	[more]
abca4a	1.181e-92	28.83	retinal-specific ATP-binding cassette transporter-...	[more]
zgc:172302	7.560e-92	31.49	zgc:172302 [Source:ZFIN;Acc:ZDB-GENE-081205-5]	[more]
zgc:172302	1.018e-89	29.92	zgc:172302 [Source:ZFIN;Acc:ZDB-GENE-081205-5]	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ENSPMAT00000002495.1	4.985e-44	27.59	pep scaffold:Pmarinus_7.0:GL480265:53:27909:1 gene...	[more]
abca12	1.831e-34	27.62	ATP-binding cassette, sub-family A (ABC1), member ...	[more]
ENSPMAT00000006988.1	1.146e-6	58.33	pep scaffold:Pmarinus_7.0:GL478499:147909:176415:-...	[more]
ENSPMAT00000006855.1	2.349e-6	26.40	pep scaffold:Pmarinus_7.0:GL486953:391:4596:1 gene...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46878	2.818e-93	31.59	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38879	3.739e-83	29.18	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48951	3.356e-22	33.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32071	2.766e-8	29.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28092	4.536e-8	31.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000045391.1	3.270e-102	30.62	ATP-binding cassette sub-family A member 1-like [S...	[more]
ENSORLT00000046301.1	4.183e-102	30.62	ATP-binding cassette sub-family A member 1-like [S...	[more]
zgc:172302	3.963e-91	29.93	ATP-binding cassette sub-family A member 1 [Source...	[more]
ENSORLT00000025407.2	1.831e-86	29.34	ATP-binding cassette sub-family A member 1 [Source...	[more]
abca1a	6.792e-86	29.11	ATP-binding cassette sub-family A member 1 [Source...	[more]

BLAST of ATP-binding cassette sub-family A member 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000029534.1	0.000e+0	89.34	SMESG000029534.1	[more]
SMESG000029537.1	0.000e+0	69.98	SMESG000029537.1	[more]
SMESG000032861.1	0.000e+0	57.95	SMESG000032861.1	[more]
SMESG000032891.1	0.000e+0	57.83	SMESG000032891.1	[more]
SMESG000068605.1	9.008e-6	55.14	SMESG000068605.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30023044 ID=SMED30023044|Name=ATP-binding cassette sub-family A member 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2501bp
CAGTGACAGAATTGCTATCATTTCCCAGGGAAAACTCCAATGTTGCGGCT
CATCAGTGTTTTTGAAACGGAAATTCGGCGATGGATATCGATTGATCCTG
GTAAAGAATTTCAACGCTCAAAAAGAAAATTTCCGCAAAGGAATTTCTAA
TTCCGGAGATAAGTTATTGCAATTTATCAAGTCCCATATTCCGGATGCGA
AGATGGAAACCGAAACAATGACTCAATGGAGCTTTGTTTTACCGCAAAAT
GATAGCAATAGTTGCAAATTCTCTGGGCTATTTGTGAATCTCGATGAAGA
AATTGACAACTTGAATGCGTTGTCATATGGATTGTCGGACACATCTCTTG
AGGAAGTGTTTATTAGGGTAGCTGATGATCCAGCAAAAATAAACGAGGAA
ACAAAGAATGAAAAACTGATTCCAGATAACTTGAATAGAATTGCTGTCTA
TGGTGACATAGAAAACCAGGAACCCTTTCTAGACCTCGAGGACCTCAATC
AGCAGGCGTTTGTTGATAAATCCTTGATTTCATTGAATTTTAATAGAAAT
CATAAATTATTAAGAGGATTTCCCCTATTAAAACAGCAAATAATTGGACT
GCAAATTAAAAGATTCCATTACGCAAAACGAAACAAAAAAGGGATTTTCG
CTGAATTGATATTACCGATTTTAATGATTACACTAATGATTGCTTTATTG
AAACTCGTAAATCCCCTGGAAAGCTTACCGGCAATGGAAATCAGTCCCTG
GTTGATGATGCCAAAATCTAGATCAATAAATTTAAATACATTTTATCGGA
AAGAAAATCAATTAAATTTTTCGATAACAAATCAATTGGGAAATAAAAAT
TCAATAAATCCTTTGACGGATCGATTGGAAAGCGAATATCGATCCGATCT
CGGTGAATCGGGAATCAGGTGCATGAATCCATCAATTTATCGATCAACCC
ATTATCGGTGTTTCCCTGAATATAAAAACAATAAATGGTCACCTATTCCT
AATGGAAACATTCCATTAATTAGCCCAGAATGTGATTGCAATACAACCGG
ATATCAGATCTGCAATGATCCTCGCAGCGGTGGTCCACCGAATTCATACC
GAATAATGACCAGTAGTGATAAACTGAACAATTTAACCGGATATAATATA
TCGGATTATTTATTGAAAAACTTTCCTAAACTATCACGAAAACTTTATGG
CGGTTTTCAATTTGTGCTACCCAGCACTTTTGGATGGTCATCGAAACTAA
TAGGAGACTCTCCGTTCTGGGAGGAATTACGCGATTTTGTGAATGCTTCC
CAGGCTAATCATAATCAATCGAATTTGAATTCATTGAAATTTATTGATTA
TCTTCAAAAAACCTTTAAGATATACGGAATAAAGACCTCATTCACTCGAA
TATGGGCCAATTCCAAAGGCTACGTGTCAATGCCAGCATATGCAAATATT
TTCAGCAATTTACTGCTGAGATCTAGATTGAATAAATCAGCAGTGAAATT
TATCGATTATGGAATCTCAGTGTCAAACTTCCCGATTGAAATGGAACAAT
CGACTAAATTTTTAGACCTAGTCAATCAGATGATTCTCGAAATGTCATTG
GCTATTTTCGTAATATTTGGACTATCTTTTATTCCGGCTAGTTTTGTGAT
ATTTTTAGTCGAAGAAAGGGTAAGTGGTTCCAAGCGGCAGCAATTCGTGT
CGGGAATTAACCCCTACGTGTATTGGGTATCCAATTTCTTGTGGGACATC
ATGAAATACATCATTCCCATTATTATCATCATAATAATTTTTATTGCCTT
TGATTATCAATCATATATCGGCAGTAAAAATGCTCTTGCTTTCATTCTTC
TTTTAATTTTCTACGGATTAGCTATTATTCCCCATATGTATCCATTTAGC
TTCTTCATTTCCACACCAAGCACCGCATTTGTGGTGTTAAATGCCTACAA
TTTATTAGTGGGTTCGATAACTACAATGTCCACTTTCATTCTAGACATAA
TAGAAGACACTGATGAAACGTTTAGGCCTACAAATGAAATCTTGAAGAAA
GTATTTTTGATATTTCCTCAATACGATTTAGGTAGAGGAATGATAGATTT
ATCTTCAAATTATATAAAGTACAACATGACGGATGGGTATGCAAAATATG
ATGCATTTGATTGGGAAGTTGCTAGTGAAAAGTTGGCATCTCTTATCTTA
TTATTTTTATTATGGTGGATCATTTTGATAATAATAGAAAGGGGCGTAAT
AAATCGAGTTCTTTACCGGATGTTAAAAGTATCTTATTTTAATAATAAGA
TTAAAAAAACAGAAGATTTCGATATTTCTTTGGAAAAAAATCGAATGAAT
TCTGAACAAAAGTTTGATGATGTGTTGCAAGTTATCAATTTGACTAAAAT
ATACAATAGGACTTTCAATTTTAGAAGTGTTTGTTGTAAAAATAAAAATA
ATGATGTCGAAAATGAAAATCAAAAATTTGCTGTTAATAATCTGTGTTTT
G

protein sequence of SMED30023044-orf-1

>SMED30023044-orf-1 ID=SMED30023044-orf-1|Name=SMED30023044-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=833bp
SDRIAIISQGKLQCCGSSVFLKRKFGDGYRLILVKNFNAQKENFRKGISN
SGDKLLQFIKSHIPDAKMETETMTQWSFVLPQNDSNSCKFSGLFVNLDEE
IDNLNALSYGLSDTSLEEVFIRVADDPAKINEETKNEKLIPDNLNRIAVY
GDIENQEPFLDLEDLNQQAFVDKSLISLNFNRNHKLLRGFPLLKQQIIGL
QIKRFHYAKRNKKGIFAELILPILMITLMIALLKLVNPLESLPAMEISPW
LMMPKSRSINLNTFYRKENQLNFSITNQLGNKNSINPLTDRLESEYRSDL
GESGIRCMNPSIYRSTHYRCFPEYKNNKWSPIPNGNIPLISPECDCNTTG
YQICNDPRSGGPPNSYRIMTSSDKLNNLTGYNISDYLLKNFPKLSRKLYG
GFQFVLPSTFGWSSKLIGDSPFWEELRDFVNASQANHNQSNLNSLKFIDY
LQKTFKIYGIKTSFTRIWANSKGYVSMPAYANIFSNLLLRSRLNKSAVKF
IDYGISVSNFPIEMEQSTKFLDLVNQMILEMSLAIFVIFGLSFIPASFVI
FLVEERVSGSKRQQFVSGINPYVYWVSNFLWDIMKYIIPIIIIIIIFIAF
DYQSYIGSKNALAFILLLIFYGLAIIPHMYPFSFFISTPSTAFVVLNAYN
LLVGSITTMSTFILDIIEDTDETFRPTNEILKKVFLIFPQYDLGRGMIDL
SSNYIKYNMTDGYAKYDAFDWEVASEKLASLILLFLLWWIILIIIERGVI
NRVLYRMLKVSYFNNKIKKTEDFDISLEKNRMNSEQKFDDVLQVINLTKI
YNRTFNFRSVCCKNKNNDVENENQKFAVNNLCF

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0042626	ATPase activity, coupled to transmembrane movement of substances
GO:0000166	nucleotide binding
GO:0005215	transporter activity
GO:0005524	ATP binding
GO:0016887	ATPase activity

Vocabulary: **biological process**
Term	Definition
GO:0055085	transmembrane transport
GO:0006810	transport

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0002032	epidermal cell
PLANA:0002089	reproductive organ
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR026082	ABCA

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PFAM	PF12698	ABC2_membrane_3	coord: 443..743 e-value: 1.8E-36 score: 125.9
None	No IPR available	PANTHER	PTHR19229:SF185		coord: 2..811
None	No IPR available	TMHMM	TMhelix		coord: 576..598
None	No IPR available	TMHMM	TMhelix		coord: 214..236
None	No IPR available	TMHMM	TMhelix		coord: 613..635
None	No IPR available	TMHMM	TMhelix		coord: 728..750
None	No IPR available	TMHMM	TMhelix		coord: 531..553
None	No IPR available	TMHMM	TMhelix		coord: 642..664
IPR026082	ABC transporter A	PANTHER	PTHR19229	ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA	coord: 2..811

Main menu

ATP-binding cassette sub-family A member 1

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Owlery

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