Calcineurin subunit B type

Overview
NameCalcineurin subunit B type
Smed IDSMED30023025
Length (bp)975
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Calcineurin subunit B type (SMED30023025) t-SNE clustered cells

Violin plots show distribution of expression levels for Calcineurin subunit B type (SMED30023025) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Calcineurin subunit B type (SMED30023025) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Calcineurin subunit B type (SMED30023025) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30023025

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30023025h1SMcG0001336 Contig38700uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30023025h1SMcG0001336 Contig38700newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30023025h1SMcG0001336 dd_Smed_v4_4924_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30023025h1SMcG0001336 dd_Smed_v4_4924_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30023025h1SMcG0001336 dd_Smed_v4_4924_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior sideSMED30023025h1SMcG0001336 dd_Smed_v4_4924_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30023025h1SMcG0001336 dd_Smed_v4_4924_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30023025h1SMcG0001336 dd_Smed_v6_4924_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Calcineurin subunit B type vs. Ensembl Human
Match: PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha [Source:HGNC Symbol;Acc:HGNC:9317])

HSP 1 Score: 269.24 bits (687), Expect = 1.124e-90
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Human
Match: PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha [Source:HGNC Symbol;Acc:HGNC:9317])

HSP 1 Score: 266.929 bits (681), Expect = 1.615e-89
Identity = 128/153 (83.66%), Postives = 145/153 (94.77%), Query Frame = 3
Query:   87 GNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            GNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:   21 GNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 173          
BLAST of Calcineurin subunit B type vs. Ensembl Human
Match: PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha [Source:HGNC Symbol;Acc:HGNC:9317])

HSP 1 Score: 251.521 bits (641), Expect = 9.350e-84
Identity = 121/144 (84.03%), Postives = 137/144 (95.14%), Query Frame = 3
Query:  114 LCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            +CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 144          
BLAST of Calcineurin subunit B type vs. Ensembl Human
Match: PPP3R2 (protein phosphatase 3 regulatory subunit B, beta [Source:HGNC Symbol;Acc:HGNC:9318])

HSP 1 Score: 251.906 bits (642), Expect = 9.902e-84
Identity = 120/154 (77.92%), Postives = 140/154 (90.91%), Query Frame = 3
Query:   81 SMGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEF 542
            +MGNEAS P E+CS FD DE++RLG+RF+KLDLD SGSLSVEEFMSLP+L+ NPLV+RVI++FD+DG+GEVDFKEFI G SQFSVKG++E KLRFAF IYDMD+DG+ISNGELFQVLK+MVGNNL D QLQQ+VDKTII  DKDGDGKIS+EEF
Sbjct:    3 TMGNEASYPAEMCSHFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRRVIDVFDTDGDGEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLKMMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEF 156          
BLAST of Calcineurin subunit B type vs. Ensembl Human
Match: PPP3R2 (protein phosphatase 3 regulatory subunit B, beta [Source:HGNC Symbol;Acc:HGNC:9318])

HSP 1 Score: 250.366 bits (638), Expect = 2.968e-83
Identity = 120/153 (78.43%), Postives = 139/153 (90.85%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEF 542
            MGNEAS P E+CS FD DE++RLG+RF+KLDLD SGSLSVEEFMSLP+L+ NPLV+RVI++FD+DG+GEVDFKEFI G SQFSVKG++E KLRFAF IYDMD+DG+ISNGELFQVLK+MVGNNL D QLQQ+VDKTII  DKDGDGKIS+EEF
Sbjct:    1 MGNEASYPAEMCSHFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRRVIDVFDTDGDGEVDFKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQVLKMMVGNNLTDWQLQQLVDKTIIILDKDGDGKISFEEF 153          
BLAST of Calcineurin subunit B type vs. Ensembl Celegans
Match: cnb-1 (Protein phosphatase 2B regulatory subunit cnb-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EDN6])

HSP 1 Score: 261.536 bits (667), Expect = 5.102e-88
Identity = 125/154 (81.17%), Postives = 143/154 (92.86%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MG +ASLP+E+CS FD  ELRRL +RF+KLD+DGSGSLSVEEFMSLP+LQQNPLVQRVI+IFD DGNGEVDF+EFI G+SQFSVKG+K  KL+FAF+IYDMDRDGFISNGELFQVLK+MVGNNLKD+QLQQIVDKTI+F DKDGDGKIS++EF 
Sbjct:    1 MGADASLPMEMCSNFDAYELRRLTRRFKKLDVDGSGSLSVEEFMSLPELQQNPLVQRVIDIFDEDGNGEVDFREFIQGISQFSVKGDKNTKLKFAFRIYDMDRDGFISNGELFQVLKMMVGNNLKDSQLQQIVDKTILFHDKDGDGKISFQEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Celegans
Match: cnb-1 (Protein phosphatase 2B regulatory subunit cnb-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EDN6])

HSP 1 Score: 261.151 bits (666), Expect = 7.970e-88
Identity = 125/154 (81.17%), Postives = 143/154 (92.86%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MG +ASLP+E+CS FD  ELRRL +RF+KLD+DGSGSLSVEEFMSLP+LQQNPLVQRVI+IFD DGNGEVDF+EFI G+SQFSVKG+K  KL+FAF+IYDMDRDGFISNGELFQVLK+MVGNNLKD+QLQQIVDKTI+F DKDGDGKIS++EF 
Sbjct:    1 MGADASLPMEMCSNFDAYELRRLTRRFKKLDVDGSGSLSVEEFMSLPELQQNPLVQRVIDIFDEDGNGEVDFREFIQGISQFSVKGDKNTKLKFAFRIYDMDRDGFISNGELFQVLKMMVGNNLKDSQLQQIVDKTILFHDKDGDGKISFQEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Celegans
Match: chpf-2 (Calcineurin-like EF-Hand Protein Family member [Source:UniProtKB/TrEMBL;Acc:O16343])

HSP 1 Score: 112.464 bits (280), Expect = 1.053e-29
Identity = 64/159 (40.25%), Postives = 103/159 (64.78%), Query Frame = 3
Query:  120 STFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIF----DSDGN---GEVDFKEFIDGMSQFS----VKGN----KEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVRS 551
            + F++ ++ RL  RF  LD +G G LS ++F+++P+L  NPL  R+I+ F    DSDG+   G++ F++F+  ++ F     VK N    ++ KLRFAFK+YD++++ +I+  E   +L  MVG N+   QL +I DKT+  AD+D DGKIS+E+F R+
Sbjct:   21 TQFNKHQILRLYTRFASLDKNGQGYLSRDDFLNVPELAVNPLGDRIIDAFFTLGDSDGDSKSGQLTFRQFVRILAHFQPISKVKDNALNSRKDKLRFAFKMYDLNKNNYITREEFKVILNSMVGANITSDQLDKIADKTLEEADQDRDGKISFEDFCRA 179          
BLAST of Calcineurin subunit B type vs. Ensembl Celegans
Match: chpf-1 (Calcineurin-like EF-Hand Protein Family member [Source:UniProtKB/TrEMBL;Acc:Q23643])

HSP 1 Score: 104.375 bits (259), Expect = 1.120e-26
Identity = 67/179 (37.43%), Postives = 109/179 (60.89%), Query Frame = 3
Query:   84 MGNEASLPI------ELCST--FDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIF----DSDGNGE---VDFKEFIDGMSQFS----VKGN----KEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVRS 551
            MGN +SL +      E+ S   F+++++ RL  RF  LD  G G LS ++F+++P+L  NPL  R+++ F     S+G+ E   ++F++F+  ++ F     VK N    ++ KL FAFK+YD++++ +I+  E   +L  MVG N+   QL +I D+TI  AD D DGKIS++EF R+
Sbjct:    1 MGNSSSLMLRDEEIEEIMSETEFNRNQIVRLYSRFLSLDKKGQGFLSRDDFLNVPELAVNPLGDRIVDAFFTLASSNGDNEEQQLNFRQFVRILAHFQPISRVKKNALNSRKDKLLFAFKMYDLNKNDYITREEFKVILNSMVGANITSDQLDKIADRTIEEADADRDGKISFDEFCRA 179          
BLAST of Calcineurin subunit B type vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 84.3445 bits (207), Expect = 9.309e-20
Identity = 51/148 (34.46%), Postives = 84/148 (56.76%), Query Frame = 3
Query:  114 LCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMS-LPQLQQNPL---VQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            +     ++++    + F   D DG G+++ +E  + +  L QNP    +Q +I   D+DGNG +DF EF+  M++     + E ++R AF+++D D +GFIS  EL  V+      NL +    + VD+ I  AD DGDG+++YEEFV
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVM-----TNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143          
BLAST of Calcineurin subunit B type vs. Ensembl Fly
Match: CanB2 (gene:FBgn0015614 transcript:FBtr0309866)

HSP 1 Score: 262.692 bits (670), Expect = 2.035e-88
Identity = 127/154 (82.47%), Postives = 143/154 (92.86%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNE SLP+E+CS FD DE+RRLGKRFRKLDLD SG+LSV+EFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI G+SQFSVKG+K +KLRFAF+IYDMD DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTI FADKD DGKIS++EF 
Sbjct:    1 MGNETSLPMEMCSNFDADEIRRLGKRFRKLDLDNSGALSVDEFMSLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQGVSQFSVKGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIGFADKDEDGKISFDEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Fly
Match: CanB2 (gene:FBgn0015614 transcript:FBtr0088930)

HSP 1 Score: 262.692 bits (670), Expect = 2.035e-88
Identity = 127/154 (82.47%), Postives = 143/154 (92.86%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNE SLP+E+CS FD DE+RRLGKRFRKLDLD SG+LSV+EFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI G+SQFSVKG+K +KLRFAF+IYDMD DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTI FADKD DGKIS++EF 
Sbjct:    1 MGNETSLPMEMCSNFDADEIRRLGKRFRKLDLDNSGALSVDEFMSLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQGVSQFSVKGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIGFADKDEDGKISFDEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Fly
Match: CanB (gene:FBgn0010014 transcript:FBtr0070764)

HSP 1 Score: 261.536 bits (667), Expect = 7.134e-88
Identity = 124/154 (80.52%), Postives = 143/154 (92.86%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNE SLP+++CS FD DE+RRLGKRFRKLDLD SG+LS++EFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI G+SQFSV+G+K +KLRFAF+IYDMD DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTI FADKD DGKIS++EF 
Sbjct:    1 MGNETSLPMDMCSNFDADEIRRLGKRFRKLDLDNSGALSIDEFMSLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQGVSQFSVRGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTICFADKDEDGKISFDEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Fly
Match: CanB (gene:FBgn0010014 transcript:FBtr0308348)

HSP 1 Score: 261.536 bits (667), Expect = 7.134e-88
Identity = 124/154 (80.52%), Postives = 143/154 (92.86%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNE SLP+++CS FD DE+RRLGKRFRKLDLD SG+LS++EFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI G+SQFSV+G+K +KLRFAF+IYDMD DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTI FADKD DGKIS++EF 
Sbjct:    1 MGNETSLPMDMCSNFDADEIRRLGKRFRKLDLDNSGALSIDEFMSLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQGVSQFSVRGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTICFADKDEDGKISFDEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Fly
Match: Cib2 (gene:FBgn0034558 transcript:FBtr0304717)

HSP 1 Score: 116.316 bits (290), Expect = 3.829e-31
Identity = 61/153 (39.87%), Postives = 88/153 (57.52%), Query Frame = 3
Query:  117 CSTFDQDELRRLGKRFRKLDLD-----------GSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEF 542
            C+ F + E+ R+ KRFR+L  D            S  +  E    +P+L++NP  +R+ E F  DG G + F++F+D +S FS +  ++ K+ +AFKIYD D+DGFI + +L   L  M  N L   + QQI DK I  AD DGDGK+S  EF
Sbjct:   19 CTFFTRKEILRVHKRFRELRPDLVPRQMTEGQASSVKVPCECIEKMPELRENPFRRRICEAFSRDGQGNLSFEDFLDALSVFSEQAPRDIKVFYAFKIYDFDQDGFIGHADLMSCLTTMTKNELSPEEHQQIADKVIEEADVDGDGKLSILEF 171          
BLAST of Calcineurin subunit B type vs. Ensembl Zebrafish
Match: ppp3r1b (protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b [Source:ZFIN;Acc:ZDB-GENE-040912-18])

HSP 1 Score: 269.24 bits (687), Expect = 7.148e-91
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Zebrafish
Match: ppp3r1a (protein phosphatase 3, regulatory subunit B, alpha a [Source:ZFIN;Acc:ZDB-GENE-081113-3])

HSP 1 Score: 269.24 bits (687), Expect = 8.060e-91
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEMKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Zebrafish
Match: chp1 (calcineurin-like EF-hand protein 1 [Source:ZFIN;Acc:ZDB-GENE-030131-4086])

HSP 1 Score: 108.227 bits (269), Expect = 7.808e-28
Identity = 63/157 (40.13%), Postives = 90/157 (57.32%), Query Frame = 3
Query:  120 STFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQF-SVKGN-------------KEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVR 548
            + F   ++ RL  RF  LD   +G LS E+F  +P+L  NPL  R+I  F  +G  +V+F+ F+  ++ F  V+ N             +  KL FAF++YD+DRD  IS  EL QVL++MVG N+ D QL  I D+TI  AD +GD  IS+ EF +
Sbjct:   21 TGFSHSQITRLYSRFHSLDKGENGGLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPVEDNEKNKDLTGEPLNSRTNKLLFAFRLYDLDRDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADTNGDMCISFNEFTK 177          
BLAST of Calcineurin subunit B type vs. Ensembl Zebrafish
Match: chp2 (calcineurin-like EF-hand protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-5810])

HSP 1 Score: 96.6709 bits (239), Expect = 1.764e-23
Identity = 62/169 (36.69%), Postives = 91/169 (53.85%), Query Frame = 3
Query:  126 FDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVK--------------GNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVRSSAEWMYIRKWSSI 590
            F    + RL +RF  LD +  G L  ++F ++ +L  NP+  R+I+ F S G   VDF  F+  ++ F                  ++  KL+FAF++YD D+DG IS  EL +VL+ M+G  + + QL+ I D+TI  AD D D  IS+EEF R S E + I    SI
Sbjct:   24 FSPAHIIRLYERFEALDKERRGHLCPQDFGAIKELAMNPIGDRIIDAFFSPGKDTVDFHTFVKILAHFRPVDKDRPKEPNSPEPINSRSNKLKFAFQLYDQDKDGKISRDELLKVLRDMLGLQVTEEQLESIADRTIQEADLDRDDAISFEEF-RKSLEKVNIDHKMSI 191          
BLAST of Calcineurin subunit B type vs. Ensembl Zebrafish
Match: chp2 (calcineurin-like EF-hand protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-5810])

HSP 1 Score: 96.6709 bits (239), Expect = 1.764e-23
Identity = 62/169 (36.69%), Postives = 91/169 (53.85%), Query Frame = 3
Query:  126 FDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVK--------------GNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVRSSAEWMYIRKWSSI 590
            F    + RL +RF  LD +  G L  ++F ++ +L  NP+  R+I+ F S G   VDF  F+  ++ F                  ++  KL+FAF++YD D+DG IS  EL +VL+ M+G  + + QL+ I D+TI  AD D D  IS+EEF R S E + I    SI
Sbjct:   24 FSPAHIIRLYERFEALDKERRGHLCPQDFGAIKELAMNPIGDRIIDAFFSPGKDTVDFHTFVKILAHFRPVDKDRPKEPNSPEPINSRSNKLKFAFQLYDQDKDGKISRDELLKVLRDMLGLQVTEEQLESIADRTIQEADLDRDDAISFEEF-RKSLEKVNIDHKMSI 191          
BLAST of Calcineurin subunit B type vs. Ensembl Xenopus
Match: hspe1 (heat shock protein family E (Hsp10) member 1 [Source:Xenbase;Acc:XB-GENE-963412])

HSP 1 Score: 269.24 bits (687), Expect = 1.019e-90
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Xenopus
Match: hspe1 (heat shock protein family E (Hsp10) member 1 [Source:Xenbase;Acc:XB-GENE-963412])

HSP 1 Score: 250.366 bits (638), Expect = 1.481e-77
Identity = 122/157 (77.71%), Postives = 140/157 (89.17%), Query Frame = 3
Query:  123 TFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVRSSAEWMYIRKWSSIY 593
            + D DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF   S   + +    SIY
Sbjct:   42 SIDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVSM-LVCVAHLPSIY 197          
BLAST of Calcineurin subunit B type vs. Ensembl Xenopus
Match: chp1 (calcineurin-like EF-hand protein 1 [Source:NCBI gene;Acc:448152])

HSP 1 Score: 112.079 bits (279), Expect = 3.689e-29
Identity = 63/154 (40.91%), Postives = 93/154 (60.39%), Query Frame = 3
Query:  126 FDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQF-SVKGN------------KEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVR 548
            F   ++ RL  RF  LD   +G+LS E+F  +P+L  NPL  R+I  F ++G  +V+F+ F+  ++ F  ++ N            +  KL FAF++YD+D+D  IS  EL QVL++MVG N+ D QL  I D+TI  AD+DGD  IS+ EFV+
Sbjct:   23 FSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFTEGEDQVNFRGFMRTLAHFRPIEDNSKDANSQEPLNSRSNKLLFAFRLYDLDKDDKISREELLQVLRMMVGVNISDDQLGSIADRTIQEADQDGDSAISFTEFVK 176          
BLAST of Calcineurin subunit B type vs. Ensembl Xenopus
Match: chp1 (calcineurin-like EF-hand protein 1 [Source:NCBI gene;Acc:448152])

HSP 1 Score: 110.538 bits (275), Expect = 1.092e-28
Identity = 62/152 (40.79%), Postives = 92/152 (60.53%), Query Frame = 3
Query:  132 QDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQF-SVKGN------------KEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVR 548
              ++ RL  RF  LD   +G+LS E+F  +P+L  NPL  R+I  F ++G  +V+F+ F+  ++ F  ++ N            +  KL FAF++YD+D+D  IS  EL QVL++MVG N+ D QL  I D+TI  AD+DGD  IS+ EFV+
Sbjct:   14 HSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFTEGEDQVNFRGFMRTLAHFRPIEDNSKDANSQEPLNSRSNKLLFAFRLYDLDKDDKISREELLQVLRMMVGVNISDDQLGSIADRTIQEADQDGDSAISFTEFVK 165          
BLAST of Calcineurin subunit B type vs. Ensembl Xenopus
Match: fads2 (fatty acid desaturase 2 [Source:Xenbase;Acc:XB-GENE-1010230])

HSP 1 Score: 87.4261 bits (215), Expect = 6.561e-20
Identity = 51/151 (33.77%), Postives = 79/151 (52.32%), Query Frame = 3
Query:  117 CSTFDQDELRRLGKRFRKL-------DLDGSGSLSV--EEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEF 542
            C+ F + E+ RL  R+R L       D      + +  E   S+P+L+ NP  QR+ E+F  DG+G +   +F+D  S  S    K+ K  +AFKIYD + D +I   +L + L  +  N L   ++  + +K I  AD D DGK+S E+F
Sbjct:   19 CTFFTRKEILRLFNRYRDLAPQLVPDDYTNKPDVKIPYELIGSMPELKDNPFRQRIAEVFSEDGDGNMTLDDFLDMFSVLSEMAPKDLKAFYAFKIYDFNNDDYICKSDLEKTLNKLTRNELTPEEVCLVCEKVIDEADVDNDGKLSLEDF 169          
BLAST of Calcineurin subunit B type vs. Ensembl Mouse
Match: Ppp3r1 (protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) [Source:MGI Symbol;Acc:MGI:107172])

HSP 1 Score: 269.24 bits (687), Expect = 7.715e-91
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Mouse
Match: Ppp3r2 (protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II) [Source:MGI Symbol;Acc:MGI:107171])

HSP 1 Score: 247.669 bits (631), Expect = 3.940e-82
Identity = 121/153 (79.08%), Postives = 137/153 (89.54%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEF 542
            MGNEAS   ELC+ FDQ+E+RRLGK FRKLDLD SGSLS+EEFM LP+LQQNPLV RVI+IFD+DGNGEVDF EFI G SQFSVKG++E KLRFAF+IYDMD DGFISNGELFQVLK+MVGNNLKD QLQQ+VDK+I+  DKDGDG+IS+EEF
Sbjct:    1 MGNEASYQTELCNHFDQEEIRRLGKSFRKLDLDKSGSLSIEEFMRLPELQQNPLVGRVIDIFDTDGNGEVDFHEFIVGTSQFSVKGDEEQKLRFAFRIYDMDNDGFISNGELFQVLKMMVGNNLKDWQLQQLVDKSILVLDKDGDGRISFEEF 153          
BLAST of Calcineurin subunit B type vs. Ensembl Mouse
Match: Chp1 (calcineurin-like EF hand protein 1 [Source:MGI Symbol;Acc:MGI:1927185])

HSP 1 Score: 114.39 bits (285), Expect = 3.082e-30
Identity = 65/156 (41.67%), Postives = 93/156 (59.62%), Query Frame = 3
Query:  126 FDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFS----------VKG-----NKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVR 548
            F   ++ RL  RF  LD   +G+LS E+F  +P+L  NPL  R+I  F S+G  +V+F+ F+  ++ F           V G     ++  KL FAF++YD+D+D  IS  EL QVL++MVG N+ D QL  I D+TI  AD+DGD  IS+ EFV+
Sbjct:   23 FSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFSEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVK 178          
BLAST of Calcineurin subunit B type vs. Ensembl Mouse
Match: Chp1 (calcineurin-like EF hand protein 1 [Source:MGI Symbol;Acc:MGI:1927185])

HSP 1 Score: 114.39 bits (285), Expect = 3.282e-30
Identity = 65/156 (41.67%), Postives = 93/156 (59.62%), Query Frame = 3
Query:  126 FDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQF----------SVKG-----NKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVR 548
            F   ++ RL  RF  LD   +G+LS E+F  +P+L  NPL  R+I  F S+G  +V+F+ F+  ++ F           V G     ++  KL FAF++YD+D+D  IS  EL QVL++MVG N+ D QL  I D+TI  AD+DGD  IS+ EFV+
Sbjct:   23 FSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFSEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDKDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVK 178          
BLAST of Calcineurin subunit B type vs. Ensembl Mouse
Match: Chp2 (calcineurin-like EF hand protein 2 [Source:MGI Symbol;Acc:MGI:1917511])

HSP 1 Score: 103.605 bits (257), Expect = 4.064e-26
Identity = 67/173 (38.73%), Postives = 95/173 (54.91%), Query Frame = 3
Query:  120 STFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEA----------------KLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVRSSAEWMYIRKWSSI 590
            + F Q  L RL  RF+ LD D  G LS  +   +  L  NPL  R+I+ F  +G+  + F  F   ++ F     ++A                KLRFAF++YD+DRDG IS  E+ QVL++MVG  + D QL+ I D+T+  AD+DGDG +S+ EF + S E M I +  SI
Sbjct:   21 TGFSQASLLRLYHRFQALDRDEKGFLSRLDLQQIGALAVNPLGDRIIDSFFPNGSQRLYFAGFARVLAYFRPIDEEDATLRDPKQPEPLNSRMNKLRFAFQLYDLDRDGKISRNEMLQVLRLMVGVQVTDEQLESITDRTVQEADEDGDGAVSFLEFTK-SLEKMNIEQKMSI 192          
BLAST of Calcineurin subunit B type vs. UniProt/SwissProt
Match: sp|P63100|CANB1_RAT (Calcineurin subunit B type 1 OS=Rattus norvegicus OX=10116 GN=Ppp3r1 PE=1 SV=2)

HSP 1 Score: 269.24 bits (687), Expect = 5.396e-90
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. UniProt/SwissProt
Match: sp|Q63810|CANB1_MOUSE (Calcineurin subunit B type 1 OS=Mus musculus OX=10090 GN=Ppp3r1 PE=1 SV=3)

HSP 1 Score: 269.24 bits (687), Expect = 5.396e-90
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. UniProt/SwissProt
Match: sp|P63098|CANB1_HUMAN (Calcineurin subunit B type 1 OS=Homo sapiens OX=9606 GN=PPP3R1 PE=1 SV=2)

HSP 1 Score: 269.24 bits (687), Expect = 5.396e-90
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. UniProt/SwissProt
Match: sp|P63099|CANB1_BOVIN (Calcineurin subunit B type 1 OS=Bos taurus OX=9913 GN=PPP3R1 PE=1 SV=2)

HSP 1 Score: 269.24 bits (687), Expect = 5.396e-90
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. UniProt/SwissProt
Match: sp|Q24214|CANB2_DROME (Calcineurin subunit B type 2 OS=Drosophila melanogaster OX=7227 GN=CanB2 PE=1 SV=2)

HSP 1 Score: 262.692 bits (670), Expect = 2.040e-87
Identity = 127/154 (82.47%), Postives = 143/154 (92.86%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNE SLP+E+CS FD DE+RRLGKRFRKLDLD SG+LSV+EFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI G+SQFSVKG+K +KLRFAF+IYDMD DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTI FADKD DGKIS++EF 
Sbjct:    1 MGNETSLPMEMCSNFDADEIRRLGKRFRKLDLDNSGALSVDEFMSLPELQQNPLVQRVIDIFDADGNGEVDFKEFIQGVSQFSVKGDKLSKLRFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIGFADKDEDGKISFDEFC 154          
BLAST of Calcineurin subunit B type vs. TrEMBL
Match: V3ZQE0 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_216002 PE=4 SV=1)

HSP 1 Score: 276.174 bits (705), Expect = 3.507e-90
Identity = 132/154 (85.71%), Postives = 147/154 (95.45%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNE SLP+ELCSTFD DE++RLGKRFRKLDLD SGSLSVEEFM+LP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE+KLRFAFKIYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII AD DGDGKIS+EEF 
Sbjct:    1 MGNENSLPLELCSTFDADEIKRLGKRFRKLDLDNSGSLSVEEFMTLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGISQFSVKGDKESKLRFAFKIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIIHADTDGDGKISFEEFC 154          
BLAST of Calcineurin subunit B type vs. TrEMBL
Match: R7U4E2 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_3297 PE=4 SV=1)

HSP 1 Score: 275.789 bits (704), Expect = 4.176e-90
Identity = 132/154 (85.71%), Postives = 148/154 (96.10%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNE +LP+ELCSTFD DE++RLGKRF+KLDLD SGSLSV+EFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE+KLRFAFKIYDMD+DGFISNGELFQVLK+MVGNNLKDAQLQQIVDKTII AD DGDGKIS+EEF 
Sbjct:    1 MGNEVTLPMELCSTFDADEIKRLGKRFKKLDLDNSGSLSVDEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKESKLRFAFKIYDMDKDGFISNGELFQVLKMMVGNNLKDAQLQQIVDKTIIHADTDGDGKISFEEFC 154          
BLAST of Calcineurin subunit B type vs. TrEMBL
Match: A8D8A2 (Calcineurin subunit B OS=Artemia franciscana OX=6661 PE=2 SV=1)

HSP 1 Score: 275.789 bits (704), Expect = 4.410e-90
Identity = 133/154 (86.36%), Postives = 148/154 (96.10%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNE+SLP+ELCSTFD DE+RRLGKRFRKLDLD SGSLSV+EFM+LP+LQQNPLVQRVI+IFDSDGNGEVDFKEFI G+SQFSVKG+KE+KLRFAF+IYDMD DGFISNGELFQVLK+MVGNNLKDAQLQQIVDKTI+FADKD DGK+S+EEF 
Sbjct:    1 MGNESSLPMELCSTFDPDEIRRLGKRFRKLDLDNSGSLSVDEFMTLPELQQNPLVQRVIDIFDSDGNGEVDFKEFIQGVSQFSVKGDKESKLRFAFRIYDMDNDGFISNGELFQVLKMMVGNNLKDAQLQQIVDKTILFADKDEDGKVSFEEFC 154          
BLAST of Calcineurin subunit B type vs. TrEMBL
Match: A0A0V0JAM0 (Calcineurin subunit B type 1 (Fragment) OS=Schistocephalus solidus OX=70667 GN=CANB1 PE=4 SV=1)

HSP 1 Score: 276.559 bits (706), Expect = 4.834e-90
Identity = 137/164 (83.54%), Postives = 152/164 (92.68%), Query Frame = 3
Query:   57 RQNYW*IYSMGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVR 548
            R + W    MGNEASLP ELCSTFD +E++RLGKRF+KLDLDGSGSLSVEEFMSLP+LQQNPLV RVI+IFD+DGNGEVDFKEFI+GMSQFSVKGNKEAKL FAFKIYDMD DGFISNGELFQVLK+MVGNNLKDAQLQQIVDKTI+FAD+DGDGKIS++EF +
Sbjct:   11 RGSTWSSGKMGNEASLP-ELCSTFDVEEIKRLGKRFKKLDLDGSGSLSVEEFMSLPELQQNPLVSRVIDIFDTDGNGEVDFKEFIEGMSQFSVKGNKEAKLNFAFKIYDMDDDGFISNGELFQVLKMMVGNNLKDAQLQQIVDKTIMFADQDGDGKISFKEFCQ 173          
BLAST of Calcineurin subunit B type vs. TrEMBL
Match: A0A0R3T9T8 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS3826 PE=4 SV=1)

HSP 1 Score: 275.018 bits (702), Expect = 8.204e-90
Identity = 134/155 (86.45%), Postives = 150/155 (96.77%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVR 548
            MGNEASLP ELCSTFD +E++RLGKRF+KLDLDGSGSLSVEEFMSLP+LQQNPLV RVIEIFD+DGNGEVDFKEFI+GMSQFSVKGNKEAKL FAFKIYD+D+DG+ISNGELFQVLK+MVGNNLKDAQLQQIVDKTI+FAD+DGDG+IS+EEF +
Sbjct:    1 MGNEASLP-ELCSTFDVEEIKRLGKRFKKLDLDGSGSLSVEEFMSLPELQQNPLVARVIEIFDTDGNGEVDFKEFIEGMSQFSVKGNKEAKLNFAFKIYDVDKDGYISNGELFQVLKMMVGNNLKDAQLQQIVDKTIMFADQDGDGRISFEEFCQ 154          
BLAST of Calcineurin subunit B type vs. Ensembl Cavefish
Match: ENSAMXT00000038285.1 (calcineurin subunit B type 1 [Source:NCBI gene;Acc:103042847])

HSP 1 Score: 269.24 bits (687), Expect = 6.058e-91
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Cavefish
Match: ppp3r1a (calcineurin subunit B type 1 [Source:NCBI gene;Acc:103037384])

HSP 1 Score: 268.085 bits (684), Expect = 2.195e-90
Identity = 128/154 (83.12%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDF+EFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFQEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Cavefish
Match: ENSAMXT00000049698.1 (calcineurin subunit B type 1 [Source:NCBI gene;Acc:103042847])

HSP 1 Score: 246.128 bits (627), Expect = 7.729e-82
Identity = 125/155 (80.65%), Postives = 142/155 (91.61%), Query Frame = 3
Query:   84 MGNEASL-PIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            +GN+ SL P    S FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 IGNQFSLYP---PSLFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 152          
BLAST of Calcineurin subunit B type vs. Ensembl Cavefish
Match: ENSAMXT00000045317.1 (calcineurin subunit B type 1 [Source:NCBI gene;Acc:103042847])

HSP 1 Score: 243.432 bits (620), Expect = 8.776e-81
Identity = 118/141 (83.69%), Postives = 134/141 (95.04%), Query Frame = 3
Query:  123 TFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            + D DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:   12 SVDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 152          
BLAST of Calcineurin subunit B type vs. Ensembl Cavefish
Match: chp1 (calcineurin like EF-hand protein 1 [Source:NCBI gene;Acc:103021582])

HSP 1 Score: 110.538 bits (275), Expect = 6.909e-29
Identity = 63/157 (40.13%), Postives = 92/157 (58.60%), Query Frame = 3
Query:  120 STFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQF-SVKGN-------------KEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVR 548
            + F   ++ RL  RF  LD   +G+LS E+F  +P+L  NPL  R+I  F  +G  +V+F+ F+  ++ F  V+ N             +  KL FAF++YD+DRD  IS  EL QVL++MVG N+ D QL  I D+TI  AD +GD  IS+ EF++
Sbjct:   21 TGFSHSQITRLYSRFHSLDKGENGALSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPVEDNEKNKDPTAEPLNSRNNKLLFAFRLYDLDRDDKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADTNGDMSISFSEFIK 177          
BLAST of Calcineurin subunit B type vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009304.1 (pep scaffold:Pmarinus_7.0:GL479988:26077:30241:1 gene:ENSPMAG00000008415.1 transcript:ENSPMAT00000009304.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 257.684 bits (657), Expect = 4.387e-87
Identity = 122/153 (79.74%), Postives = 144/153 (94.12%), Query Frame = 3
Query:   87 GNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            GN+ S P+++C+ FD DE++RLGKRFRKLDLD SGSLSV+EFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+K+ KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTI+ ADKDGDG+IS+EEF 
Sbjct:    2 GNDLSYPLDMCTHFDADEIKRLGKRFRKLDLDNSGSLSVDEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKDQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTILNADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000781.1 (pep scaffold:Pmarinus_7.0:GL476952:2198:8857:1 gene:ENSPMAG00000000709.1 transcript:ENSPMAT00000000781.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 257.299 bits (656), Expect = 5.953e-87
Identity = 124/153 (81.05%), Postives = 141/153 (92.16%), Query Frame = 3
Query:   87 GNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            GNE+S P+E+CS FD DE++RLGKRFRKLDLDGSGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLR  +   +MDRDG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    2 GNESSYPLEMCSHFDADEIKRLGKRFRKLDLDGSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRCKYSSCNMDRDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004125.1 (pep scaffold:Pmarinus_7.0:GL483005:7747:12994:-1 gene:ENSPMAG00000003768.1 transcript:ENSPMAT00000004125.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 203.756 bits (517), Expect = 6.555e-66
Identity = 95/136 (69.85%), Postives = 116/136 (85.29%), Query Frame = 3
Query:  138 ELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            ELRRL  RF KLDLD SG+LS +EF+SLP+L  NPLV+RV++I DSDG+GEVDF EFI+G+S+F++ G KE KL+FAF+IYD+DRDGFI+NGELF VLK MVG NL+D QLQQIVDK+II AD DGDGK+S+ EF 
Sbjct:   13 ELRRLSARFHKLDLDSSGALSADEFLSLPELHNNPLVRRVVDILDSDGDGEVDFAEFIEGISRFTINGTKEEKLKFAFQIYDVDRDGFITNGELFGVLKTMVGRNLRDPQLQQIVDKSIISADADGDGKVSFPEFC 148          
BLAST of Calcineurin subunit B type vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008747.1 (pep scaffold:Pmarinus_7.0:GL492596:4314:5073:1 gene:ENSPMAG00000007919.1 transcript:ENSPMAT00000008747.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 141.354 bits (355), Expect = 9.290e-43
Identity = 69/78 (88.46%), Postives = 75/78 (96.15%), Query Frame = 3
Query:  129 DQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLR 362
            D DE+RRLGKRFRKLDLDGSGSLSVEEFMSLP+LQQNPLVQRVI IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLR
Sbjct:    1 DPDEIRRLGKRFRKLDLDGSGSLSVEEFMSLPELQQNPLVQRVIHIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLR 78          
BLAST of Calcineurin subunit B type vs. Ensembl Sea Lamprey
Match: chp2 (calcineurin-like EF-hand protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-5810])

HSP 1 Score: 112.849 bits (281), Expect = 1.853e-30
Identity = 63/153 (41.18%), Postives = 93/153 (60.78%), Query Frame = 3
Query:  126 FDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQF----SVK----------GNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEF 542
            F   ++ RL  RF  LD   +G+LS E+F  +P+L  NPL  R+I  F  +G  +V+F+ F+  ++ F    +VK           ++ +KL+FAF++YD+D+D  IS  EL QVL++MVG N+ D QL  I D+TI  AD+DGD  IS+ EF
Sbjct:   23 FSHSQITRLYSRFTSLDKGENGTLSREDFQRIPELAINPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPVDTVKEKDPNAPAALNSRASKLKFAFRLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDNAISFTEF 175          
BLAST of Calcineurin subunit B type vs. Ensembl Yeast
Match: CNB1 (Calcineurin B; regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (stress-response transcription factor); other calcineurin subunit encoded by CNA1 and/or CMP1; regulates function of Aly1p alpha-arrestin; myristoylation by Nmt1p reduces calcineurin activity in response to submaximal Ca signals, is needed to prevent constitutive phosphatase activity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001673])

HSP 1 Score: 188.734 bits (478), Expect = 4.335e-60
Identity = 93/153 (60.78%), Postives = 122/153 (79.74%), Query Frame = 3
Query:  120 STFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVRSSAEWMYIRK 578
            + FD+DE+ RL KRF KLD D SGS+   EFMS+P +  NPL  R++E+FD+D +G+VDF+EFI G+S FS +G+K+ KLRFAFKIYD+D+DGFISNGELF VLKIMVG+NL D QLQQIVD+TI+  D DGDG++S+EEF +++ E   + K
Sbjct:   16 TNFDRDEIERLRKRFMKLDRDSSGSIDKNEFMSIPGVSSNPLAGRIMEVFDADNSGDVDFQEFITGLSIFSGRGSKDEKLRFAFKIYDIDKDGFISNGELFIVLKIMVGSNLDDEQLQQIVDRTIVENDSDGDGRLSFEEF-KNAIETTEVAK 167          
BLAST of Calcineurin subunit B type vs. Ensembl Yeast
Match: FRQ1 (N-myristoylated calcium-binding protein; may have a role in intracellular signaling through its regulation of the phosphatidylinositol 4-kinase Pik1p; member of the recoverin/frequenin branch of the EF-hand superfamily; human NCS1 functionally complements the heat sensitivity of a frq1 ts mutant [Source:SGD;Acc:S000002781])

HSP 1 Score: 65.0846 bits (157), Expect = 4.025e-13
Identity = 49/157 (31.21%), Postives = 81/157 (51.59%), Query Frame = 3
Query:  120 STFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSL-----PQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGEL-------FQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVRSS 554
            + FD+ E+++  K F  L    SG L+ E+F+ +     P          +  +FD D NG + F+EFI  +S  S +G  E KL +AF++YD++ DG+I+  E+       ++++  MV  N  +A  +  V K     DK+ DG I+ +EF   S
Sbjct:   20 TYFDRREIQQWHKGF--LRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTS-RGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGS 173          
BLAST of Calcineurin subunit B type vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 59.3066 bits (142), Expect = 2.004e-11
Identity = 43/148 (29.05%), Postives = 76/148 (51.35%), Query Frame = 3
Query:  114 LCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMS-LPQLQQNPLVQRVIEIF---DSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            + S   ++++    + F   D D +GS+S  E  + +  L  +P    V ++    D DGN +++F EF+  MS+     + E +L  AFK++D + DG IS  EL  VL   +G  L DA++  ++ +       DG G+I+ ++F 
Sbjct:    1 MSSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVL-TSIGEKLTDAEVDDMLREV-----SDGSGEINIQQFA 142          
BLAST of Calcineurin subunit B type vs. Ensembl Nematostella
Match: EDO48535 (Predicted protein; Protein phosphatase 3 (Formerly 2B), regulatory subunit B [Source:UniProtKB/TrEMBL;Acc:A7RJ82])

HSP 1 Score: 258.84 bits (660), Expect = 2.833e-87
Identity = 125/154 (81.17%), Postives = 142/154 (92.21%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEASLP ++ + FD DE+RRLGKRFRKLDLD SGSLSVEEFMSLP+LQQNPLVQRVI IFD+DGNGEVDFKEFI+G+SQFSVKG+KE+KL+FAF+IYDMD DG+ISNGELFQVLK+MVGNNLK+ QLQQIVDKTI+ ADKDGDGKI + EF 
Sbjct:    1 MGNEASLPGDMVTHFDADEIRRLGKRFRKLDLDNSGSLSVEEFMSLPELQQNPLVQRVITIFDADGNGEVDFKEFIEGVSQFSVKGDKESKLKFAFRIYDMDNDGYISNGELFQVLKMMVGNNLKETQLQQIVDKTILNADKDGDGKICFSEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Nematostella
Match: EDO40303 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7U9])

HSP 1 Score: 99.7525 bits (247), Expect = 2.877e-25
Identity = 54/152 (35.53%), Postives = 85/152 (55.92%), Query Frame = 3
Query:  126 FDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIF-----DSDGNGEVDFKEFIDGMSQF--------SVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEF 542
            F   ++ RL  RF  LD    G+L+ E+F+ +P+L  NPL  R+++ F     ++    + +FK+F+  ++ F        +    +E KL+FAF+IYD+D DG+IS  +L  +L +MVG  + D  L  I D+ I  AD DGD  IS+ E 
Sbjct:   23 FSPKQISRLYSRFSNLDKANQGTLTREDFLRIPELAINPLGDRIVDAFFMNQEEAGLQEQCNFKQFVRTLAHFRPFHGHSPNPLNTREEKLKFAFRIYDIDSDGYISKTDLIAILHMMVGVTISDEHLTGIADRAISDADTDGDKLISFAEL 174          
BLAST of Calcineurin subunit B type vs. Ensembl Nematostella
Match: EDO47515 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM01])

HSP 1 Score: 92.0485 bits (227), Expect = 1.996e-22
Identity = 50/147 (34.01%), Postives = 84/147 (57.14%), Query Frame = 3
Query:  120 STFDQDELRRLGKRFRKLD-----LDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNN-LKDAQLQQIVDKTIIFADKDGDGKISYEEF 542
            + F Q E+    KRF +LD     L+ +  LS  + ++LP+L+ NP   R+ ++F S  +G + F++F+D MS FS    K  K+ +AF+IYD + D +I   +L +V+  + G   L D  +Q +++K    AD D D ++S+ EF
Sbjct:   20 TYFTQKEILHCFKRFMQLDPEAVRLNKNAKLSQRKILTLPELKVNPFRDRICKVFSSSKDGSLTFEDFLDMMSVFSENAPKSVKVEYAFRIYDFNEDDYICENDLKKVIMRLCGEQRLSDDNMQAMIEKIFEEADLDEDNQLSFAEF 166          
BLAST of Calcineurin subunit B type vs. Ensembl Nematostella
Match: EDO46518 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPI8])

HSP 1 Score: 85.5001 bits (210), Expect = 2.395e-20
Identity = 51/149 (34.23%), Postives = 85/149 (57.05%), Query Frame = 3
Query:  114 LCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMS-LPQLQQNPL---VQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVR 548
            +     ++++    + F   D DG G+++ +E  + +  L QNP    +Q +I   D+DGNG +DF EF+  M++     + E ++R AF+++D D +GFIS  EL  V+      NL +    + VD+ I  AD DGDG+++YEEFV+
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVM-----TNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVK 144          
BLAST of Calcineurin subunit B type vs. Ensembl Nematostella
Match: EDO36724 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHW4])

HSP 1 Score: 85.1149 bits (209), Expect = 6.157e-20
Identity = 45/152 (29.61%), Postives = 86/152 (56.58%), Query Frame = 3
Query:  117 CSTFDQDELRRLGKRFRKL----------DLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEF 542
            C+ F + ++ R+ KR+R L          +L+    L +   + LP+L++NP   R+ ++F  +G+G + F +F++ MS  S    +E K+++AFKI+D D D  +   +L Q +  + G +LK+ ++Q +V+  +  AD D  G +++ EF
Sbjct:   19 CTFFTRADILRIHKRYRALHPVLIPDDYKELETQPLLKMRHLLKLPELKENPFKCRICQVFSVNGSGALTFDDFLNMMSVLSDSAPRELKVKYAFKIFDFDGDQKLGPTDLAQTVLSVTGGDLKEDEVQFVVESLLSEADIDETGYLNFLEF 170          
BLAST of Calcineurin subunit B type vs. Ensembl Medaka
Match: ENSORLT00000002911.2 (protein phosphatase 3 regulatory subunit B, alpha [Source:NCBI gene;Acc:101161991])

HSP 1 Score: 269.24 bits (687), Expect = 6.021e-91
Identity = 129/154 (83.77%), Postives = 146/154 (94.81%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEAS P+E+CS FD DE++RLGKRF+KLDLD SGSLSVEEFMSLP+LQQNPLVQRVI+IFD+DGNGEVDFKEFI+G+SQFSVKG+KE KLRFAF+IYDMD+DG+ISNGELFQVLK+MVGNNLKD QLQQIVDKTII ADKDGDG+IS+EEF 
Sbjct:    1 MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFC 154          
BLAST of Calcineurin subunit B type vs. Ensembl Medaka
Match: ENSORLT00000043908.1 (calcineurin subunit B type 1-like [Source:NCBI gene;Acc:101168674])

HSP 1 Score: 190.66 bits (483), Expect = 5.159e-60
Identity = 105/148 (70.95%), Postives = 128/148 (86.49%), Query Frame = 3
Query:   81 SMGNEA-SLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDG 521
            S G EA S P+ L S     E++RL KRF+KLDLDGSGSLSV EFMSLP+LQQNPLV RVI+IFD+DG+GE+DF+EF++G+SQFSV G++E KL+FAF+IYD+D+DGFISNGELFQVLK M G+NLKD +LQQ+VDKTII AD+DGDG
Sbjct:    6 SGGVEAPSPPVTLLSHDPAGEIKRLKKRFKKLDLDGSGSLSVGEFMSLPELQQNPLVPRVIDIFDTDGDGEIDFREFMEGISQFSVGGSREQKLQFAFRIYDVDKDGFISNGELFQVLKTMAGSNLKDWELQQVVDKTIISADQDGDG 153          
BLAST of Calcineurin subunit B type vs. Ensembl Medaka
Match: ENSORLT00000002914.2 (calcineurin subunit B type 1-like [Source:NCBI gene;Acc:101168674])

HSP 1 Score: 187.578 bits (475), Expect = 7.514e-59
Identity = 101/139 (72.66%), Postives = 123/139 (88.49%), Query Frame = 3
Query:  105 PIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDG 521
            P ELC      E++RL KRF+KLDLDGSGSLSV EFMSLP+LQQNPLV RVI+IFD+DG+GE+DF+EF++G+SQFSV G++E KL+FAF+IYD+D+DGFISNGELFQVLK M G+NLKD +LQQ+VDKTII AD+DGDG
Sbjct:    8 PEELCQA---GEIKRLKKRFKKLDLDGSGSLSVGEFMSLPELQQNPLVPRVIDIFDTDGDGEIDFREFMEGISQFSVGGSREQKLQFAFRIYDVDKDGFISNGELFQVLKTMAGSNLKDWELQQVVDKTIISADQDGDG 143          
BLAST of Calcineurin subunit B type vs. Ensembl Medaka
Match: ENSORLT00000002912.2 (calcineurin subunit B type 1-like [Source:NCBI gene;Acc:101168674])

HSP 1 Score: 187.193 bits (474), Expect = 8.751e-59
Identity = 101/145 (69.66%), Postives = 124/145 (85.52%), Query Frame = 3
Query:   87 GNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDG 521
            G  A   + LC      E++RL KRF+KLDLDGSGSLSV EFMSLP+LQQNPLV RVI+IFD+DG+GE+DF+EF++G+SQFSV G++E KL+FAF+IYD+D+DGFISNGELFQVLK M G+NLKD +LQQ+VDKTII AD+DGDG
Sbjct:    2 GTTAPTSLSLC--LLAGEIKRLKKRFKKLDLDGSGSLSVGEFMSLPELQQNPLVPRVIDIFDTDGDGEIDFREFMEGISQFSVGGSREQKLQFAFRIYDVDKDGFISNGELFQVLKTMAGSNLKDWELQQVVDKTIISADQDGDG 144          
BLAST of Calcineurin subunit B type vs. Ensembl Medaka
Match: ENSORLT00000043316.1 (calcineurin subunit B type 1-like [Source:NCBI gene;Acc:101168674])

HSP 1 Score: 186.422 bits (472), Expect = 2.300e-58
Identity = 89/116 (76.72%), Postives = 108/116 (93.10%), Query Frame = 3
Query:  174 DLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDG 521
            DLDGSGSLSV EFMSLP+LQQNPLV RVI+IFD+DG+GE+DF+EF++G+SQFSV G++E KL+FAF+IYD+D+DGFISNGELFQVLK M G+NLKD +LQQ+VDKTII AD+DGDG
Sbjct:   44 DLDGSGSLSVGEFMSLPELQQNPLVPRVIDIFDTDGDGEIDFREFMEGISQFSVGGSREQKLQFAFRIYDVDKDGFISNGELFQVLKTMAGSNLKDWELQQVVDKTIISADQDGDG 159          
BLAST of Calcineurin subunit B type vs. Planmine SMEST
Match: SMESG000019278.1 (SMESG000019278.1)

HSP 1 Score: 307.76 bits (787), Expect = 3.666e-106
Identity = 153/154 (99.35%), Postives = 153/154 (99.35%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEF 
Sbjct:    1 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFC 154          
BLAST of Calcineurin subunit B type vs. Planmine SMEST
Match: SMESG000081409.1 (SMESG000081409.1)

HSP 1 Score: 286.574 bits (732), Expect = 7.386e-98
Identity = 137/154 (88.96%), Postives = 151/154 (98.05%), Query Frame = 3
Query:   84 MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            MGNE+SLP+E+CSTFDQ+E+RRLGKRF+KLDLDGSGSLSV+EFMSLPQLQQNPLVQRVIEIFDSD NGEVDFKEFI+GMSQFSVKGNKE+KL+FAFKIYD+DRDGFISNGELFQVLK+MVGNNLK+ QLQQIVDKTI+FADKDGDGKISYEEF 
Sbjct:    1 MGNESSLPVEMCSTFDQEEIRRLGKRFKKLDLDGSGSLSVDEFMSLPQLQQNPLVQRVIEIFDSDSNGEVDFKEFIEGMSQFSVKGNKESKLKFAFKIYDIDRDGFISNGELFQVLKMMVGNNLKETQLQQIVDKTIMFADKDGDGKISYEEFC 154          
BLAST of Calcineurin subunit B type vs. Planmine SMEST
Match: SMESG000018297.1 (SMESG000018297.1)

HSP 1 Score: 101.679 bits (252), Expect = 1.015e-25
Identity = 57/154 (37.01%), Postives = 93/154 (60.39%), Query Frame = 3
Query:  108 IELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQQNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQF------SVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFVRS 551
            I + + F   ++RRL  RF  LD + +G L+ + F+ +P+L  NPL  R++  F  +   E++FK+F+  ++ F      S K ++E KL+F F +YD+D+D  IS  EL  +L++MVG N+   Q+  I ++T+  AD D DG ISY EF ++
Sbjct:   17 ISIETGFSDKQIRRLYNRFVALDKEDNGYLTRQTFLLIPELAINPLGDRIVHEFFKNNVDELNFKDFVHKLAIFRKTSVDSTKSSRELKLKFLFDLYDLDKDEKISLEELMGMLQMMVGENITSEQMNNIGERTMAEADLDNDGYISYGEFEKA 170          
BLAST of Calcineurin subunit B type vs. Planmine SMEST
Match: SMESG000034095.1 (SMESG000034095.1)

HSP 1 Score: 84.3445 bits (207), Expect = 9.760e-20
Identity = 51/148 (34.46%), Postives = 84/148 (56.76%), Query Frame = 3
Query:  114 LCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMS-LPQLQQNPL---VQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            +     ++++    + F   D DG G+++ +E  + +  L QNP    +Q +I   D+DGNG +DF EF+  M++     + E ++R AF+++D D +GFIS  EL  V+      NL +    + VD+ I  AD DGDG+++YEEFV
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVM-----TNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143          
BLAST of Calcineurin subunit B type vs. Planmine SMEST
Match: SMESG000010769.1 (SMESG000010769.1)

HSP 1 Score: 84.3445 bits (207), Expect = 9.760e-20
Identity = 51/148 (34.46%), Postives = 84/148 (56.76%), Query Frame = 3
Query:  114 LCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMS-LPQLQQNPL---VQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYDMDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISYEEFV 545
            +     ++++    + F   D DG G+++ +E  + +  L QNP    +Q +I   D+DGNG +DF EF+  M++     + E ++R AF+++D D +GFIS  EL  V+      NL +    + VD+ I  AD DGDG+++YEEFV
Sbjct:    1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVM-----TNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143          
The following BLAST results are available for this feature:
BLAST of Calcineurin subunit B type vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PPP3R11.124e-9083.77protein phosphatase 3 regulatory subunit B, alpha ... [more]
PPP3R11.615e-8983.66protein phosphatase 3 regulatory subunit B, alpha ... [more]
PPP3R19.350e-8484.03protein phosphatase 3 regulatory subunit B, alpha ... [more]
PPP3R29.902e-8477.92protein phosphatase 3 regulatory subunit B, beta [... [more]
PPP3R22.968e-8378.43protein phosphatase 3 regulatory subunit B, beta [... [more]
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BLAST of Calcineurin subunit B type vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cnb-15.102e-8881.17Protein phosphatase 2B regulatory subunit cnb-1 [... [more]
cnb-17.970e-8881.17Protein phosphatase 2B regulatory subunit cnb-1 [... [more]
chpf-21.053e-2940.25Calcineurin-like EF-Hand Protein Family member [S... [more]
chpf-11.120e-2637.43Calcineurin-like EF-Hand Protein Family member [S... [more]
cmd-19.309e-2034.46Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630... [more]
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BLAST of Calcineurin subunit B type vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CanB22.035e-8882.47gene:FBgn0015614 transcript:FBtr0309866[more]
CanB22.035e-8882.47gene:FBgn0015614 transcript:FBtr0088930[more]
CanB7.134e-8880.52gene:FBgn0010014 transcript:FBtr0070764[more]
CanB7.134e-8880.52gene:FBgn0010014 transcript:FBtr0308348[more]
Cib23.829e-3139.87gene:FBgn0034558 transcript:FBtr0304717[more]
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BLAST of Calcineurin subunit B type vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ppp3r1b7.148e-9183.77protein phosphatase 3 (formerly 2B), regulatory s1... [more]
ppp3r1a8.060e-9183.77protein phosphatase 3, regulatory subunit B, alpha... [more]
chp17.808e-2840.13calcineurin-like EF-hand protein 1 [Source:ZFIN;Ac... [more]
chp21.764e-2336.69calcineurin-like EF-hand protein 2 [Source:ZFIN;Ac... [more]
chp21.764e-2336.69calcineurin-like EF-hand protein 2 [Source:ZFIN;Ac... [more]
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BLAST of Calcineurin subunit B type vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hspe11.019e-9083.77heat shock protein family E (Hsp10) member 1 [Sour... [more]
hspe11.481e-7777.71heat shock protein family E (Hsp10) member 1 [Sour... [more]
chp13.689e-2940.91calcineurin-like EF-hand protein 1 [Source:NCBI ge... [more]
chp11.092e-2840.79calcineurin-like EF-hand protein 1 [Source:NCBI ge... [more]
fads26.561e-2033.77fatty acid desaturase 2 [Source:Xenbase;Acc:XB-GEN... [more]
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BLAST of Calcineurin subunit B type vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ppp3r17.715e-9183.77protein phosphatase 3, regulatory subunit B, alpha... [more]
Ppp3r23.940e-8279.08protein phosphatase 3, regulatory subunit B, alpha... [more]
Chp13.082e-3041.67calcineurin-like EF hand protein 1 [Source:MGI Sym... [more]
Chp13.282e-3041.67calcineurin-like EF hand protein 1 [Source:MGI Sym... [more]
Chp24.064e-2638.73calcineurin-like EF hand protein 2 [Source:MGI Sym... [more]
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BLAST of Calcineurin subunit B type vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P63100|CANB1_RAT5.396e-9083.77Calcineurin subunit B type 1 OS=Rattus norvegicus ... [more]
sp|Q63810|CANB1_MOUSE5.396e-9083.77Calcineurin subunit B type 1 OS=Mus musculus OX=10... [more]
sp|P63098|CANB1_HUMAN5.396e-9083.77Calcineurin subunit B type 1 OS=Homo sapiens OX=96... [more]
sp|P63099|CANB1_BOVIN5.396e-9083.77Calcineurin subunit B type 1 OS=Bos taurus OX=9913... [more]
sp|Q24214|CANB2_DROME2.040e-8782.47Calcineurin subunit B type 2 OS=Drosophila melanog... [more]
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BLAST of Calcineurin subunit B type vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
V3ZQE03.507e-9085.71Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
R7U4E24.176e-9085.71Uncharacterized protein OS=Capitella teleta OX=283... [more]
A8D8A24.410e-9086.36Calcineurin subunit B OS=Artemia franciscana OX=66... [more]
A0A0V0JAM04.834e-9083.54Calcineurin subunit B type 1 (Fragment) OS=Schisto... [more]
A0A0R3T9T88.204e-9086.45Uncharacterized protein OS=Rodentolepis nana OX=10... [more]
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BLAST of Calcineurin subunit B type vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000038285.16.058e-9183.77calcineurin subunit B type 1 [Source:NCBI gene;Acc... [more]
ppp3r1a2.195e-9083.12calcineurin subunit B type 1 [Source:NCBI gene;Acc... [more]
ENSAMXT00000049698.17.729e-8280.65calcineurin subunit B type 1 [Source:NCBI gene;Acc... [more]
ENSAMXT00000045317.18.776e-8183.69calcineurin subunit B type 1 [Source:NCBI gene;Acc... [more]
chp16.909e-2940.13calcineurin like EF-hand protein 1 [Source:NCBI ge... [more]
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BLAST of Calcineurin subunit B type vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000009304.14.387e-8779.74pep scaffold:Pmarinus_7.0:GL479988:26077:30241:1 g... [more]
ENSPMAT00000000781.15.953e-8781.05pep scaffold:Pmarinus_7.0:GL476952:2198:8857:1 gen... [more]
ENSPMAT00000004125.16.555e-6669.85pep scaffold:Pmarinus_7.0:GL483005:7747:12994:-1 g... [more]
ENSPMAT00000008747.19.290e-4388.46pep scaffold:Pmarinus_7.0:GL492596:4314:5073:1 gen... [more]
chp21.853e-3041.18calcineurin-like EF-hand protein 2 [Source:ZFIN;Ac... [more]
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BLAST of Calcineurin subunit B type vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
CNB14.335e-6060.78Calcineurin B; regulatory subunit of calcineurin, ... [more]
FRQ14.025e-1331.21N-myristoylated calcium-binding protein; may have ... [more]
CMD12.004e-1129.05Calmodulin; Ca2+ binding protein that regulates Ca... [more]
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BLAST of Calcineurin subunit B type vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO485352.833e-8781.17Predicted protein; Protein phosphatase 3 (Formerly... [more]
EDO403032.877e-2535.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO475151.996e-2234.01Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO465182.395e-2034.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO367246.157e-2029.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Calcineurin subunit B type vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000002911.26.021e-9183.77protein phosphatase 3 regulatory subunit B, alpha ... [more]
ENSORLT00000043908.15.159e-6070.95calcineurin subunit B type 1-like [Source:NCBI gen... [more]
ENSORLT00000002914.27.514e-5972.66calcineurin subunit B type 1-like [Source:NCBI gen... [more]
ENSORLT00000002912.28.751e-5969.66calcineurin subunit B type 1-like [Source:NCBI gen... [more]
ENSORLT00000043316.12.300e-5876.72calcineurin subunit B type 1-like [Source:NCBI gen... [more]
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BLAST of Calcineurin subunit B type vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000019278.13.666e-10699.35SMESG000019278.1[more]
SMESG000081409.17.386e-9888.96SMESG000081409.1[more]
SMESG000018297.11.015e-2537.01SMESG000018297.1[more]
SMESG000034095.19.760e-2034.46SMESG000034095.1[more]
SMESG000010769.19.760e-2034.46SMESG000010769.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30023025 ID=SMED30023025|Name=Calcineurin subunit B type|organism=Schmidtea mediterranea sexual|type=transcript|length=975bp
TATTTATACTAGTGCTAAGTAATTTTAACCTTAGCTGTTTGATTCAGTAA
ATATTTAGACAGAATTATTGGTAAATTTATTCAATGGGAAATGAAGCGTC
CTTGCCAATTGAACTATGTTCTACATTTGATCAGGATGAATTGCGTAGAT
TAGGAAAGCGGTTTCGAAAATTAGATTTGGATGGATCGGGCTCATTGAGT
GTTGAAGAATTTATGAGTCTACCTCAATTACAGCAGAATCCATTGGTTCA
ACGTGTGATTGAAATTTTCGATAGCGATGGCAATGGTGAAGTTGACTTTA
AAGAATTTATAGATGGTATGTCTCAATTCAGCGTAAAGGGCAACAAAGAA
GCCAAATTACGATTTGCATTTAAAATTTATGACATGGATCGAGATGGGTT
CATTAGCAATGGAGAATTGTTTCAAGTTCTTAAAATTATGGTGGGAAATA
ATTTGAAAGACGCACAATTGCAACAGATTGTCGATAAAACGATAATATTT
GCTGACAAAGATGGCGACGGGAAAATTTCGTATGAAGAATTTGTTCGGTC
GTCAGCGGAATGGATGTACATACGAAAATGGTCGTCGATATATAAAATCT
TTGATTTTACAACCGTATTTTTAACCTTTATATTCTATTTTCTTTGATTG
TTGTATTTGTCACGGAGCATTGGTTGAGCTAGCAAATTCTGTATAGCTTT
TATCGGTGCATGAATATCGAATTTTTCATTTTTACTTATAGTCAAATTTT
ATTGATAAAATTATTGATAAAATTTTATATATATATTGTTAACATACTTT
TGTTGAGTTGTATTAATAATTAATTTCCTTGCTGATTTGATGTATTTCTG
CCAGCGAATCTGATTGGTTTCTGTTGGCAATTTATTGATTAAAATTCCGA
ATCTTATTATTTGAGAGAATTGTATTGGTTGAATTTGTTATAATTAATCA
ATATTTTTATTGATTTAAAAAAAAA
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protein sequence of SMED30023025-orf-1

>SMED30023025-orf-1 ID=SMED30023025-orf-1|Name=SMED30023025-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=188bp
MGNEASLPIELCSTFDQDELRRLGKRFRKLDLDGSGSLSVEEFMSLPQLQ
QNPLVQRVIEIFDSDGNGEVDFKEFIDGMSQFSVKGNKEAKLRFAFKIYD
MDRDGFISNGELFQVLKIMVGNNLKDAQLQQIVDKTIIFADKDGDGKISY
EEFVRSSAEWMYIRKWSSIYKIFDFTTVFLTFIFYFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
PLANA:0000418head
PLANA:0003001lateral region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR002048EF_hand_dom
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding