Small ubiquitin-related modifier

Overview
NameSmall ubiquitin-related modifier
Smed IDSMED30022935
Length (bp)395
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Small ubiquitin-related modifier (SMED30022935) t-SNE clustered cells

Violin plots show distribution of expression levels for Small ubiquitin-related modifier (SMED30022935) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Small ubiquitin-related modifier (SMED30022935) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Small ubiquitin-related modifier (SMED30022935) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30022935

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30022935 dd_Smed_v4_265_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30022935 dd_Smed_v4_265_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30022935 dd_Smed_v4_265_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30022935 dd_Smed_v4_265_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30022935 dd_Smed_v4_265_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30022935 dd_Smed_v4_265_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Human
Match: SUMO2 (small ubiquitin like modifier 2 [Source:HGNC Symbol;Acc:HGNC:11125])

HSP 1 Score: 114.005 bits (284), Expect = 1.988e-33
Identity = 56/95 (58.95%), Postives = 67/95 (70.53%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            MAD   KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG Y
Sbjct:    1 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 95
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Human
Match: SUMO3 (small ubiquitin like modifier 3 [Source:HGNC Symbol;Acc:HGNC:11124])

HSP 1 Score: 110.923 bits (276), Expect = 3.379e-32
Identity = 52/89 (58.43%), Postives = 64/89 (71.91%), Query Frame = 3 
Query:   42 DNNKEGTA---EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +  KEG     +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    4 EKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 92
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Human
Match: SUMO4 (small ubiquitin like modifier 4 [Source:HGNC Symbol;Acc:HGNC:21181])

HSP 1 Score: 101.293 bits (251), Expect = 1.763e-28
Identity = 48/92 (52.17%), Postives = 59/92 (64.13%), Query Frame = 3 
Query:   30 EIMADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            E+  +NN      HIN+KV GQDG+V+ FKIK+ T L KLM AYC+  GL    +RF F G  I  TD P  L+ME+ DTI+VFQ  TGG Y
Sbjct:    9 EVKTENNN-----HINLKVAGQDGSVVQFKIKRQTPLSKLMKAYCEPRGLSVKQIRFRFGGQPISGTDKPAQLEMEDEDTIDVFQQPTGGVY 95
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Human
Match: SUMO3 (small ubiquitin like modifier 3 [Source:HGNC Symbol;Acc:HGNC:11124])

HSP 1 Score: 93.2041 bits (230), Expect = 8.507e-25
Identity = 52/127 (40.94%), Postives = 64/127 (50.39%), Query Frame = 3 
Query:   42 DNNKEGTA---EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRL--------------------------------------GLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +  KEG     +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R                                       GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    4 EKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQVRHLAPPQSLPVCALVLCVPGIPRARASRGWTQMQLPEGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 130
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Human
Match: SUMO1 (small ubiquitin like modifier 1 [Source:HGNC Symbol;Acc:HGNC:12502])

HSP 1 Score: 92.0485 bits (227), Expect = 1.030e-24
Identity = 48/99 (48.48%), Postives = 63/99 (63.64%), Query Frame = 3 
Query:    3 SDLFASLLIEIMADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            SD  A    E + D  KEG  E+I +KV GQD + IHFK+K  T L+KL  +YC R G+  +++RF+F+G  I +  TP  L MEE D IEV+Q QTGG
Sbjct:    2 SDQEAKPSTEDLGDK-KEG--EYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGG 97
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Celegans
Match: smo-1 (Small ubiquitin-related modifier [Source:UniProtKB/Swiss-Prot;Acc:P55853])

HSP 1 Score: 93.9745 bits (232), Expect = 4.877e-26
Identity = 42/91 (46.15%), Postives = 63/91 (69.23%), Query Frame = 3 
Query:   36 MADNNKEG--TAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGF 302
            MAD+  +    AE+I +KV GQD   +HF++K  T++ KL  +Y DR G+  +++RF+FDG  I + DTP +L+ME++D IEV+Q Q GGF
Sbjct:    1 MADDAAQAGDNAEYIKIKVVGQDSNEVHFRVKYGTSMAKLKKSYADRTGVAVNSLRFLFDGRRINDDDTPKTLEMEDDDVIEVYQEQLGGF 91
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Fly
Match: smt3 (gene:FBgn0264922 transcript:FBtr0346716)

HSP 1 Score: 129.028 bits (323), Expect = 8.867e-40
Identity = 61/88 (69.32%), Postives = 67/88 (76.14%), Query Frame = 3 
Query:   36 MADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            M+D  K G  EHIN+KV GQD AV+ FKIKK+T LRKLMNAYCDR GL    VRF FDG  I E DTPTSL+MEE DTIEV+Q QTGG
Sbjct:    1 MSDEKKGGETEHINLKVLGQDNAVVQFKIKKHTPLRKLMNAYCDRAGLSMQVVRFRFDGQPINENDTPTSLEMEEGDTIEVYQQQTGG 88
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Fly
Match: smt3 (gene:FBgn0264922 transcript:FBtr0079356)

HSP 1 Score: 129.028 bits (323), Expect = 8.867e-40
Identity = 61/88 (69.32%), Postives = 67/88 (76.14%), Query Frame = 3 
Query:   36 MADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            M+D  K G  EHIN+KV GQD AV+ FKIKK+T LRKLMNAYCDR GL    VRF FDG  I E DTPTSL+MEE DTIEV+Q QTGG
Sbjct:    1 MSDEKKGGETEHINLKVLGQDNAVVQFKIKKHTPLRKLMNAYCDRAGLSMQVVRFRFDGQPINENDTPTSLEMEEGDTIEVYQQQTGG 88
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Zebrafish
Match: sumo3a (small ubiquitin like modifier 3a [Source:NCBI gene;Acc:406398])

HSP 1 Score: 112.079 bits (279), Expect = 7.218e-33
Identity = 53/89 (59.55%), Postives = 64/89 (71.91%), Query Frame = 3 
Query:   42 DNNKEGTA---EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            D  KEG     +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    4 DKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSIRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 92
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Zebrafish
Match: sumo2b (small ubiquitin like modifier 2b [Source:NCBI gene;Acc:445027])

HSP 1 Score: 110.538 bits (275), Expect = 2.462e-32
Identity = 55/93 (59.14%), Postives = 66/93 (70.97%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            MAD   KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    1 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLTMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 93
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Zebrafish
Match: sumo2b (small ubiquitin like modifier 2b [Source:NCBI gene;Acc:445027])

HSP 1 Score: 110.538 bits (275), Expect = 2.462e-32
Identity = 55/93 (59.14%), Postives = 66/93 (70.97%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            MAD   KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    1 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLTMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 93
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Zebrafish
Match: sumo3b (small ubiquitin like modifier 3b [Source:NCBI gene;Acc:436950])

HSP 1 Score: 110.153 bits (274), Expect = 3.156e-32
Identity = 52/89 (58.43%), Postives = 64/89 (71.91%), Query Frame = 3 
Query:   42 DNNKEGTA---EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +  KEG     +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    4 EKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSIRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 92
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Zebrafish
Match: sumo2a (small ubiquitin like modifier 2a [Source:ZFIN;Acc:ZDB-GENE-120215-155])

HSP 1 Score: 105.531 bits (262), Expect = 2.494e-30
Identity = 51/93 (54.84%), Postives = 62/93 (66.67%), Query Frame = 3 
Query:   36 MADNN-KEGTAE---HINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGF 302
            MAD   K+G      HIN++V  QDG+V+ FKIKK+  L KLM  YCDR GL    +RF+FDG +IKETDTP  L+ME+ D IEVFQ Q  G 
Sbjct:    1 MADEKTKDGVKSEKSHINLRVSSQDGSVVQFKIKKHAPLSKLMKVYCDRQGLTRKLIRFMFDGESIKETDTPALLEMEDEDAIEVFQEQLAGL 93
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Xenopus
Match: sumo3 (small ubiquitin like modifier 3 [Source:NCBI gene;Acc:100125978])

HSP 1 Score: 112.079 bits (279), Expect = 9.845e-33
Identity = 53/89 (59.55%), Postives = 64/89 (71.91%), Query Frame = 3 
Query:   42 DNNKEGTA---EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +  KEG     +HIN+KV GQDG+V+ FKIK++T L KLM AYCDR GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    4 EKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCDRQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 92
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Xenopus
Match: sumo2 (small ubiquitin-like modifier 2 [Source:NCBI gene;Acc:549160])

HSP 1 Score: 111.694 bits (278), Expect = 1.155e-32
Identity = 55/95 (57.89%), Postives = 68/95 (71.58%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            MAD+  KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG +
Sbjct:    1 MADDKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLNKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGSF 95
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Xenopus
Match: sumo3 (small ubiquitin like modifier 3 [Source:NCBI gene;Acc:100125978])

HSP 1 Score: 111.309 bits (277), Expect = 1.549e-32
Identity = 50/78 (64.10%), Postives = 60/78 (76.92%), Query Frame = 3 
Query:   66 EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +HIN+KV GQDG+V+ FKIK++T L KLM AYCDR GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:   11 DHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCDRQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 88
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Xenopus
Match: sumo3 (small ubiquitin like modifier 3 [Source:NCBI gene;Acc:100125978])

HSP 1 Score: 111.309 bits (277), Expect = 1.578e-32
Identity = 50/78 (64.10%), Postives = 60/78 (76.92%), Query Frame = 3 
Query:   66 EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +HIN+KV GQDG+V+ FKIK++T L KLM AYCDR GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    9 DHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCDRQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 86
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Xenopus
Match: sumo2 (small ubiquitin-like modifier 2 [Source:NCBI gene;Acc:549160])

HSP 1 Score: 110.153 bits (274), Expect = 6.973e-32
Identity = 49/80 (61.25%), Postives = 61/80 (76.25%), Query Frame = 3 
Query:   66 EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG +
Sbjct:   26 DHINLKVAGQDGSVVQFKIKRHTPLNKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGSF 105
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Mouse
Match: Sumo2 (small ubiquitin-like modifier 2 [Source:MGI Symbol;Acc:MGI:2158813])

HSP 1 Score: 114.005 bits (284), Expect = 1.365e-33
Identity = 56/95 (58.95%), Postives = 67/95 (70.53%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            MAD   KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG Y
Sbjct:    1 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 95
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Mouse
Match: Sumo3 (small ubiquitin-like modifier 3 [Source:MGI Symbol;Acc:MGI:1336201])

HSP 1 Score: 110.923 bits (276), Expect = 3.137e-32
Identity = 52/89 (58.43%), Postives = 64/89 (71.91%), Query Frame = 3 
Query:   42 DNNKEGTA---EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +  KEG     +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    4 EKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 92
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Mouse
Match: Sumo3 (small ubiquitin-like modifier 3 [Source:MGI Symbol;Acc:MGI:1336201])

HSP 1 Score: 110.923 bits (276), Expect = 3.694e-32
Identity = 49/78 (62.82%), Postives = 60/78 (76.92%), Query Frame = 3 
Query:   66 EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:   18 DHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 95
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Mouse
Match: Sumo3 (small ubiquitin-like modifier 3 [Source:MGI Symbol;Acc:MGI:1336201])

HSP 1 Score: 110.538 bits (275), Expect = 3.989e-32
Identity = 50/92 (54.35%), Postives = 65/92 (70.65%), Query Frame = 3 
Query:   24 LIEIMADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +  ++A    +   +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    1 MTTVLAQEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 92
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Mouse
Match: Sumo1 (small ubiquitin-like modifier 1 [Source:MGI Symbol;Acc:MGI:1197010])

HSP 1 Score: 92.0485 bits (227), Expect = 7.073e-25
Identity = 48/99 (48.48%), Postives = 63/99 (63.64%), Query Frame = 3 
Query:    3 SDLFASLLIEIMADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            SD  A    E + D  KEG  E+I +KV GQD + IHFK+K  T L+KL  +YC R G+  +++RF+F+G  I +  TP  L MEE D IEV+Q QTGG
Sbjct:    2 SDQEAKPSTEDLGDK-KEG--EYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGG 97
[Close]
BLAST of Small ubiquitin-related modifier vs. UniProt/SwissProt
Match: sp|P61959|SUMO2_RAT (Small ubiquitin-related modifier 2 OS=Rattus norvegicus OX=10116 GN=Sumo2 PE=1 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 9.547e-33
Identity = 56/95 (58.95%), Postives = 67/95 (70.53%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            MAD   KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG Y
Sbjct:    1 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 95
[Close]
BLAST of Small ubiquitin-related modifier vs. UniProt/SwissProt
Match: sp|P61958|SUMO2_PIG (Small ubiquitin-related modifier 2 OS=Sus scrofa OX=9823 GN=SUMO2 PE=3 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 9.547e-33
Identity = 56/95 (58.95%), Postives = 67/95 (70.53%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            MAD   KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG Y
Sbjct:    1 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 95
[Close]
BLAST of Small ubiquitin-related modifier vs. UniProt/SwissProt
Match: sp|P61957|SUMO2_MOUSE (Small ubiquitin-related modifier 2 OS=Mus musculus OX=10090 GN=Sumo2 PE=1 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 9.547e-33
Identity = 56/95 (58.95%), Postives = 67/95 (70.53%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            MAD   KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG Y
Sbjct:    1 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 95
[Close]
BLAST of Small ubiquitin-related modifier vs. UniProt/SwissProt
Match: sp|Q2PFW2|SUMO2_MACFA (Small ubiquitin-related modifier 2 OS=Macaca fascicularis OX=9541 GN=SUMO2 PE=3 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 9.547e-33
Identity = 56/95 (58.95%), Postives = 67/95 (70.53%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            MAD   KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG Y
Sbjct:    1 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 95
[Close]
BLAST of Small ubiquitin-related modifier vs. UniProt/SwissProt
Match: sp|P61956|SUMO2_HUMAN (Small ubiquitin-related modifier 2 OS=Homo sapiens OX=9606 GN=SUMO2 PE=1 SV=3)

HSP 1 Score: 114.005 bits (284), Expect = 9.547e-33
Identity = 56/95 (58.95%), Postives = 67/95 (70.53%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            MAD   KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG Y
Sbjct:    1 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 95
[Close]
BLAST of Small ubiquitin-related modifier vs. TrEMBL
Match: Q5BS96 (Small ubiquitin-related modifier OS=Schistosoma japonicum OX=6182 GN=SUMO-2 PE=2 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 1.043e-42
Identity = 66/90 (73.33%), Postives = 79/90 (87.78%), Query Frame = 3 
Query:   36 MADN-NKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGF 302
            MAD+ NKE  +EHIN+KVQGQ+G++IHFKI+KNT LRKLM AYC+RLGLK  +VRFIFDG ++ ETDTP SL+MEENDTIEVFQ+QTGG 
Sbjct:    1 MADSANKEAPSEHINIKVQGQEGSIIHFKIRKNTPLRKLMLAYCERLGLKQPSVRFIFDGNSVHETDTPASLEMEENDTIEVFQTQTGGL 90
[Close]
BLAST of Small ubiquitin-related modifier vs. TrEMBL
Match: A0A267EYF5 (Small ubiquitin-related modifier (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002796g1 PE=3 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 5.193e-42
Identity = 64/81 (79.01%), Postives = 72/81 (88.89%), Query Frame = 3 
Query:   57 GTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
             ++EHIN+KVQGQDGAVIHFKIKKNT LRKLM  YCDRLGL+  TVRFIFDG N++E+DTP +LDMEENDTIEVFQSQ GG
Sbjct:   18 ASSEHINLKVQGQDGAVIHFKIKKNTPLRKLMTTYCDRLGLRAQTVRFIFDGNNVEESDTPATLDMEENDTIEVFQSQVGG 98
[Close]
BLAST of Small ubiquitin-related modifier vs. TrEMBL
Match: A0A267EXW6 (Small ubiquitin-related modifier (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002796g2 PE=3 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 5.206e-42
Identity = 64/81 (79.01%), Postives = 72/81 (88.89%), Query Frame = 3 
Query:   57 GTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
             ++EHIN+KVQGQDGAVIHFKIKKNT LRKLM  YCDRLGL+  TVRFIFDG N++E+DTP +LDMEENDTIEVFQSQ GG
Sbjct:   17 ASSEHINLKVQGQDGAVIHFKIKKNTPLRKLMTTYCDRLGLRAQTVRFIFDGNNVEESDTPATLDMEENDTIEVFQSQVGG 97
[Close]
BLAST of Small ubiquitin-related modifier vs. TrEMBL
Match: C1LQV7 (Small ubiquitin-related modifier OS=Schistosoma japonicum OX=6182 GN=SUMO-2 PE=2 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 8.271e-42
Identity = 65/90 (72.22%), Postives = 78/90 (86.67%), Query Frame = 3 
Query:   36 MADN-NKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGF 302
            MAD+ NKE  +EHIN+KVQGQ+G++IH KI+KNT LRKLM AYC+RLGLK  +VRFIFDG ++ ETDTP SL+MEENDTIEVFQ+QTGG 
Sbjct:    1 MADSANKEAPSEHINIKVQGQEGSIIHIKIRKNTPLRKLMLAYCERLGLKQPSVRFIFDGNSVHETDTPASLEMEENDTIEVFQTQTGGL 90
[Close]
BLAST of Small ubiquitin-related modifier vs. TrEMBL
Match: A0A267E716 (Small ubiquitin-related modifier OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021607g1 PE=3 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 1.071e-41
Identity = 64/81 (79.01%), Postives = 72/81 (88.89%), Query Frame = 3 
Query:   57 GTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
             ++EHIN+KVQGQDGAVIHFKIKKNT LRKLM  YCDRLGL+  TVRFIFDG N++E+DTP +LDMEENDTIEVFQSQ GG
Sbjct:    6 ASSEHINLKVQGQDGAVIHFKIKKNTPLRKLMTTYCDRLGLRAQTVRFIFDGNNVEESDTPATLDMEENDTIEVFQSQVGG 86
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Cavefish
Match: sumo2b (small ubiquitin like modifier 2 [Source:NCBI gene;Acc:103044284])

HSP 1 Score: 113.235 bits (282), Expect = 2.205e-33
Identity = 56/94 (59.57%), Postives = 67/94 (71.28%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGF 302
            MAD   KEG      +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGGF
Sbjct:    1 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLTMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGF 94
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Cavefish
Match: ENSAMXT00000057127.1 (small ubiquitin-related modifier 2-like [Source:NCBI gene;Acc:103045390])

HSP 1 Score: 112.464 bits (280), Expect = 3.198e-33
Identity = 56/93 (60.22%), Postives = 66/93 (70.97%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            MAD   KEG      EHIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    1 MADEKPKEGVKTENNEHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLTMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 93
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Cavefish
Match: ENSAMXT00000035970.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000157.1:639445:644773:-1 gene:ENSAMXG00000037441.1 transcript:ENSAMXT00000035970.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 109.768 bits (273), Expect = 3.228e-32
Identity = 49/78 (62.82%), Postives = 60/78 (76.92%), Query Frame = 3 
Query:   66 EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    9 DHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSIRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 86
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Cavefish
Match: ENSAMXT00000038721.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000157.1:639445:644645:-1 gene:ENSAMXG00000037441.1 transcript:ENSAMXT00000038721.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 109.768 bits (273), Expect = 1.232e-31
Identity = 49/78 (62.82%), Postives = 60/78 (76.92%), Query Frame = 3 
Query:   66 EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:   52 DHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSIRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 129
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Cavefish
Match: ENSAMXT00000052373.1 (small ubiquitin-related modifier 2-like [Source:NCBI gene;Acc:103045390])

HSP 1 Score: 73.559 bits (179), Expect = 4.155e-18
Identity = 43/93 (46.24%), Postives = 52/93 (55.91%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            MAD   KEG      EHIN+KV GQDG+V+ FKIK++T L KLM AYC+R                         L+ME+ DTI+VFQ QTGG
Sbjct:    1 MADEKPKEGVKTENNEHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCER------------------------QLEMEDEDTIDVFQQQTGG 69
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Yeast
Match: SMT3 (Ubiquitin-like protein of the SUMO family; conjugated to lysine residues of target proteins; associates with transcriptionally active genes; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics; human homolog SUMO1 can complement yeast null mutant [Source:SGD;Acc:S000002918])

HSP 1 Score: 78.9518 bits (193), Expect = 7.451e-21
Identity = 39/78 (50.00%), Postives = 52/78 (66.67%), Query Frame = 3 
Query:   69 HINVKVQGQDGAV-IHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            HIN+KV   DG+  I FKIKK T LR+LM A+  R G +  ++RF++DG+ I+   TP  LDME+ND IE  + Q GG
Sbjct:   23 HINLKVS--DGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGG 98
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Nematostella
Match: EDO45837 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRX5])

HSP 1 Score: 75.8702 bits (185), Expect = 1.802e-19
Identity = 39/69 (56.52%), Postives = 52/69 (75.36%), Query Frame = 3 
Query:   93 QDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            QD + +HFKIKK T L+KL  AYCDR G++ ++VRF+FDG  I +  TP  L+ME++D IEV+Q QTGG
Sbjct:    7 QDNSEVHFKIKKTTQLKKLKAAYCDRQGVQMNSVRFLFDGQRINDDQTPKQLEMEDDDVIEVYQEQTGG 75
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Nematostella
Match: EDO35524 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL98])

HSP 1 Score: 44.2838 bits (103), Expect = 3.346e-6
Identity = 19/55 (34.55%), Postives = 35/55 (63.64%), Query Frame = 3 
Query:  114 FKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEV 278
            + + K+  L+ L++ YC+   L +S ++F FDG  IK + TP  L++E+ D ++V
Sbjct:  492 YTVIKDQPLQSLIDRYCEFRKLPSSKLQFSFDGDVIKGSSTPAELELEDEDILDV 546
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Medaka
Match: sumo2 (small ubiquitin-related modifier 2 [Source:NCBI gene;Acc:100335140])

HSP 1 Score: 112.849 bits (281), Expect = 2.282e-33
Identity = 50/78 (64.10%), Postives = 61/78 (78.21%), Query Frame = 3 
Query:   66 EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            EHIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP+ L+ME+ DTI+VFQ QTGG
Sbjct:   13 EHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPSQLEMEDEDTIDVFQQQTGG 90
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Medaka
Match: sumo2 (small ubiquitin-related modifier 2 [Source:NCBI gene;Acc:100335140])

HSP 1 Score: 112.849 bits (281), Expect = 2.807e-33
Identity = 50/78 (64.10%), Postives = 61/78 (78.21%), Query Frame = 3 
Query:   66 EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            EHIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP+ L+ME+ DTI+VFQ QTGG
Sbjct:   16 EHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPSQLEMEDEDTIDVFQQQTGG 93
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Medaka
Match: sumo2 (small ubiquitin like modifier 2 [Source:NCBI gene;Acc:100335143])

HSP 1 Score: 111.694 bits (278), Expect = 6.755e-33
Identity = 56/93 (60.22%), Postives = 66/93 (70.97%), Query Frame = 3 
Query:   36 MADNN-KEGTA----EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            MAD   KEG      EHIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    1 MADEKPKEGVKTENNEHINLKVAGQDGSVVQFKIKRHTPLIKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 93
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Medaka
Match: sumo4 (small ubiquitin-related modifier 4 [Source:NCBI gene;Acc:100335145])

HSP 1 Score: 110.153 bits (274), Expect = 2.629e-32
Identity = 52/89 (58.43%), Postives = 64/89 (71.91%), Query Frame = 3 
Query:   42 DNNKEGTA---EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +  KEG     +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:    4 EKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSIRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 92
[Close]
BLAST of Small ubiquitin-related modifier vs. Ensembl Medaka
Match: sumo4 (small ubiquitin-related modifier 4 [Source:NCBI gene;Acc:100335145])

HSP 1 Score: 110.153 bits (274), Expect = 4.184e-32
Identity = 49/78 (62.82%), Postives = 60/78 (76.92%), Query Frame = 3 
Query:   66 EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            +HIN+KV GQDG+V+ FKIK++T L KLM AYC+R GL    +RF FDG  I ETDTP  L+ME+ DTI+VFQ QTGG
Sbjct:   22 DHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSIRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 99
[Close]
BLAST of Small ubiquitin-related modifier vs. Planmine SMEST
Match: SMESG000056595.1 (SMESG000056595.1)

HSP 1 Score: 188.734 bits (478), Expect = 1.449e-63
Identity = 90/90 (100.00%), Postives = 90/90 (100.00%), Query Frame = 3 
Query:   36 MADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 305
            MADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY
Sbjct:    1 MADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGFY 90
[Close]
BLAST of Small ubiquitin-related modifier vs. Planmine SMEST
Match: SMESG000018835.1 (SMESG000018835.1)

HSP 1 Score: 172.17 bits (435), Expect = 6.034e-57
Identity = 84/88 (95.45%), Postives = 85/88 (96.59%), Query Frame = 3 
Query:   36 MADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGG 299
            MAD  KEGT EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETD+PTSLDMEENDTIEVFQSQTGG
Sbjct:    1 MAD--KEGTPEHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKTSTVRFIFDGVNIKETDSPTSLDMEENDTIEVFQSQTGG 86
[Close]
BLAST of Small ubiquitin-related modifier vs. Planmine SMEST
Match: SMESG000026971.1 (SMESG000026971.1)

HSP 1 Score: 49.6766 bits (117), Expect = 6.682e-8
Identity = 24/72 (33.33%), Postives = 42/72 (58.33%), Query Frame = 3 
Query:   66 EHINVKVQGQDGAVIHFKIKKNTALRKLMNAYCDRLGLKT-STVRFIFDGVNIKETDTPTSLDMEENDTIEV 278
            E IN+  Q  DG  + FK ++   +R  M A+  R+G  +   ++FI++G +I   +TP+SL+M  +  I+V
Sbjct:  187 EWINLYFQFPDGHKMRFKTRRKAMMRHSMEAFSARMGYSSIHDLKFIYNGSDIYYNETPSSLNMASDALIQV 258
The following BLAST results are available for this feature:
BLAST of Small ubiquitin-related modifier vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SUMO21.988e-3358.95small ubiquitin like modifier 2 [Source:HGNC Symbo... [more]
SUMO33.379e-3258.43small ubiquitin like modifier 3 [Source:HGNC Symbo... [more]
SUMO41.763e-2852.17small ubiquitin like modifier 4 [Source:HGNC Symbo... [more]
SUMO38.507e-2540.94small ubiquitin like modifier 3 [Source:HGNC Symbo... [more]
SUMO11.030e-2448.48small ubiquitin like modifier 1 [Source:HGNC Symbo... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
smo-14.877e-2646.15Small ubiquitin-related modifier [Source:UniProtK... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
smt38.867e-4069.32gene:FBgn0264922 transcript:FBtr0346716[more]
smt38.867e-4069.32gene:FBgn0264922 transcript:FBtr0079356[more]
back to top
BLAST of Small ubiquitin-related modifier vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sumo3a7.218e-3359.55small ubiquitin like modifier 3a [Source:NCBI gene... [more]
sumo2b2.462e-3259.14small ubiquitin like modifier 2b [Source:NCBI gene... [more]
sumo2b2.462e-3259.14small ubiquitin like modifier 2b [Source:NCBI gene... [more]
sumo3b3.156e-3258.43small ubiquitin like modifier 3b [Source:NCBI gene... [more]
sumo2a2.494e-3054.84small ubiquitin like modifier 2a [Source:ZFIN;Acc:... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sumo39.845e-3359.55small ubiquitin like modifier 3 [Source:NCBI gene;... [more]
sumo21.155e-3257.89small ubiquitin-like modifier 2 [Source:NCBI gene;... [more]
sumo31.549e-3264.10small ubiquitin like modifier 3 [Source:NCBI gene;... [more]
sumo31.578e-3264.10small ubiquitin like modifier 3 [Source:NCBI gene;... [more]
sumo26.973e-3261.25small ubiquitin-like modifier 2 [Source:NCBI gene;... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Sumo21.365e-3358.95small ubiquitin-like modifier 2 [Source:MGI Symbol... [more]
Sumo33.137e-3258.43small ubiquitin-like modifier 3 [Source:MGI Symbol... [more]
Sumo33.694e-3262.82small ubiquitin-like modifier 3 [Source:MGI Symbol... [more]
Sumo33.989e-3254.35small ubiquitin-like modifier 3 [Source:MGI Symbol... [more]
Sumo17.073e-2548.48small ubiquitin-like modifier 1 [Source:MGI Symbol... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P61959|SUMO2_RAT9.547e-3358.95Small ubiquitin-related modifier 2 OS=Rattus norve... [more]
sp|P61958|SUMO2_PIG9.547e-3358.95Small ubiquitin-related modifier 2 OS=Sus scrofa O... [more]
sp|P61957|SUMO2_MOUSE9.547e-3358.95Small ubiquitin-related modifier 2 OS=Mus musculus... [more]
sp|Q2PFW2|SUMO2_MACFA9.547e-3358.95Small ubiquitin-related modifier 2 OS=Macaca fasci... [more]
sp|P61956|SUMO2_HUMAN9.547e-3358.95Small ubiquitin-related modifier 2 OS=Homo sapiens... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
Q5BS961.043e-4273.33Small ubiquitin-related modifier OS=Schistosoma ja... [more]
A0A267EYF55.193e-4279.01Small ubiquitin-related modifier (Fragment) OS=Mac... [more]
A0A267EXW65.206e-4279.01Small ubiquitin-related modifier (Fragment) OS=Mac... [more]
C1LQV78.271e-4272.22Small ubiquitin-related modifier OS=Schistosoma ja... [more]
A0A267E7161.071e-4179.01Small ubiquitin-related modifier OS=Macrostomum li... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sumo2b2.205e-3359.57small ubiquitin like modifier 2 [Source:NCBI gene;... [more]
ENSAMXT00000057127.13.198e-3360.22small ubiquitin-related modifier 2-like [Source:NC... [more]
ENSAMXT00000035970.13.228e-3262.82pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000038721.11.232e-3162.82pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000052373.14.155e-1846.24small ubiquitin-related modifier 2-like [Source:NC... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Small ubiquitin-related modifier vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
SMT37.451e-2150.00Ubiquitin-like protein of the SUMO family; conjuga... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO458371.802e-1956.52Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO355243.346e-634.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sumo22.282e-3364.10small ubiquitin-related modifier 2 [Source:NCBI ge... [more]
sumo22.807e-3364.10small ubiquitin-related modifier 2 [Source:NCBI ge... [more]
sumo26.755e-3360.22small ubiquitin like modifier 2 [Source:NCBI gene;... [more]
sumo42.629e-3258.43small ubiquitin-related modifier 4 [Source:NCBI ge... [more]
sumo44.184e-3262.82small ubiquitin-related modifier 4 [Source:NCBI ge... [more]
back to top
BLAST of Small ubiquitin-related modifier vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000056595.11.449e-63100.00SMESG000056595.1[more]
SMESG000018835.16.034e-5795.45SMESG000018835.1[more]
SMESG000026971.16.682e-833.33SMESG000026971.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022935 ID=SMED30022935|Name=Small ubiquitin-related modifier|organism=Schmidtea mediterranea sexual|type=transcript|length=395bp
CTTCCGATCTATTTGCATCACTTTTAATTGAAATAATGGCAGATAATAAT
AAGGAAGGAACAGCTGAACATATTAATGTAAAAGTACAAGGTCAAGATGG
AGCAGTTATTCATTTTAAAATTAAAAAGAACACTGCTTTAAGGAAGCTCA
TGAATGCTTATTGTGACAGATTAGGGCTCAAAACTTCAACTGTAAGATTT
ATCTTCGATGGGGTTAATATAAAGGAAACTGATACTCCAACATCTCTTGA
TATGGAAGAAAATGATACTATTGAGGTGTTCCAGAGTCAGACTGGCGGTT
TCTATTGATGGATCATTGCGTGTTATTGATAATTATATCAATTTGTCTTT
ACCCGAAACTTGTTGTAATTATTATAAAAATATAATTATAGTATG
back to top

protein sequence of SMED30022935-orf-1

>SMED30022935-orf-1 ID=SMED30022935-orf-1|Name=SMED30022935-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=102bp
SDLFASLLIEIMADNNKEGTAEHINVKVQGQDGAVIHFKIKKNTALRKLM
NAYCDRLGLKTSTVRFIFDGVNIKETDTPTSLDMEENDTIEVFQSQTGGF
Y*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000429neoblast
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR000626Ubiquitin-like_dom
IPR022617Rad60/SUMO-like_dom
IPR029071Ubiquitin-like_domsf
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
Vocabulary: biological process
TermDefinition
GO:0016925protein sumoylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000626Ubiquitin-like domainSMARTSM00213ubq_7coord: 21..92
e-value: 3.4E-6
score: 36.6
IPR000626Ubiquitin-like domainPROSITEPS50053UBIQUITIN_2coord: 19..96
score: 14.534
NoneNo IPR availableGENE3DG3DSA:3.10.20.90coord: 9..96
e-value: 4.6E-33
score: 115.3
NoneNo IPR availablePANTHERPTHR10562:SF74SMALL UBIQUITIN-RELATED MODIFIER 3-RELATEDcoord: 17..98
NoneNo IPR availablePANTHERPTHR10562SMALL UBIQUITIN-RELATED MODIFIERcoord: 17..98
NoneNo IPR availableCDDcd16115Ubl_SUMO2_3_4coord: 20..91
e-value: 3.9546E-47
score: 143.277
IPR022617Rad60/SUMO-like domainPFAMPF11976Rad60-SLDcoord: 21..89
e-value: 3.5E-22
score: 78.0
IPR029071Ubiquitin-like domain superfamilySUPERFAMILYSSF54236Ubiquitin-likecoord: 12..96