Netrin 1

Overview
NameNetrin 1
Smed IDSMED30022921
Length (bp)1370
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Netrin 1 (SMED30022921) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Netrin 1 (SMED30022921) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30022921

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30022921h1SMcG0009805 SmedASXL_014430SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30022921h1SMcG0009805 dd_Smed_v4_14852_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30022921h1SMcG0009805 dd_Smed_v4_14852_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
prepharyngeal regionSMED30022921h1SMcG0009805 dd_Smed_v6_14852_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
cephalic gangliaSMED30022921h1SMcG0009805 AY945305smed_ncbi_20240424PMID:16033796
Cebrià et al., 2005
whole organism asexual adult colorimetric in situ hybridization evidence
ventral nerve cordSMED30022921h1SMcG0009805 AY945305smed_ncbi_20240424PMID:16033796
Cebrià et al., 2005
whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30022921h1SMcG0009805 AY945305smed_ncbi_20240424PMID:16033796
Cebrià et al., 2005
whole organism asexual adult colorimetric in situ hybridization evidence
enteric muscle cellSMED30022921h1SMcG0009805 dd_Smed_v4_14852_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30022921h1SMcG0009805 dd_Smed_v4_14852_0_1dd_Smed_v4PMID:30962434
Cote et al., 2019
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Netrin 1 vs. Ensembl Human
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029])

HSP 1 Score: 270.781 bits (691), Expect = 8.699e-84
Identity = 154/400 (38.50%), Postives = 216/400 (54.00%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +Q  PC   NG P++C+P F N         +STCG   P + C     +   E  + C +C+A    +++PP+ +TD + P N TCW S    + P  + V +T+SL K FEV Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C + +  P      + IT  N  E +C +     R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R   F  E      L    Y                      + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   +YRD+ KP+TH +AC
Sbjct:   36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKAC 401          
BLAST of Netrin 1 vs. Ensembl Human
Match: NTN3 (netrin 3 [Source:HGNC Symbol;Acc:HGNC:8030])

HSP 1 Score: 206.838 bits (525), Expect = 8.190e-60
Identity = 132/414 (31.88%), Postives = 192/414 (46.38%), Query Frame = 2
Query:   23 ILNLSVWIHSVKVIFESQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAF-KMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +L       ++     + + PC+   G P+ C+P   N     +   +STCG                   R     CDA    R++ P+ +T      +  CW S  L   P    V +TV L K+FE+ +++L+ C   P S+A+ KS D G SW P  FFS  C   + ++P      +   P    E LC    AP    D      +L FS     P G     S  L +W+T TD+R+ L R +     P  ++ +  ++                    +  +DL VGGRCKCNGHA+RCL+D    + CDC H TEG +C RCK  Y DRPWQRAT + ++ C  C C  H+ +C F+M +Y+ +  + GGVCL C+HNT G  C  C    YRD  + ++  +AC
Sbjct:    9 LLTAGTLFAALSPGPPAPADPCHDEGGAPRGCVPGLVNAALGREVLASSTCG-------------------RPATRACDASDPRRAHSPALLTSPGGTASPLCWRSESLPRAP--LNVTLTVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGP----EALC--FPAPLAQPD---GSGLLAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPS-TAGDPRDMEAVVPYS--------------------YAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRAC 371          
BLAST of Netrin 1 vs. Ensembl Human
Match: LAMC1 (laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:6492])

HSP 1 Score: 190.274 bits (482), Expect = 7.823e-52
Identity = 125/381 (32.81%), Postives = 188/381 (49.34%), Query Frame = 2
Query:   98 GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPG-QNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQ-AETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYR 1210
            GRPQ+C+P F N   NV    T+TCGT  PE+ C            + C +CDA   H  +  + +TD +   + T W S  +       + +N+T+ L K+F++ Y+ L+   + P+S AIYK       W P+Q++S  C   +       +    T  +  + LC +      ++D        + FST+ GRPS   +     L EW+T TD+R++L R   F  E  + P  LK  YY                        +SD AVGGRCKCNGHA+ C+ ++ D++ C+C HNT G +CE+C   + DRPW+RAT ++A+ C  C C   S +C F   +Y+ T   HGG C  C+ NT+G  C+ C    +R
Sbjct:   45 GRPQRCMPEFVNAAFNVTVVATNTCGTP-PEEYC---VQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKAN---RGFIRTGGDEQQALCTD-----EFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYY-----------------------AISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRST--GHGGHCTNCQDNTDGAHCERCRENFFR 388          
BLAST of Netrin 1 vs. Ensembl Human
Match: LAMC3 (laminin subunit gamma 3 [Source:HGNC Symbol;Acc:HGNC:6494])

HSP 1 Score: 186.422 bits (472), Expect = 1.378e-50
Identity = 126/378 (33.33%), Postives = 187/378 (49.47%), Query Frame = 2
Query:   98 GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQ--NEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEV-LCVELKAPERYNDYGQ-AETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHY 1207
            GRPQ+CLP F N      A+ + TCG+  PE  C +      A A  +C  CDA    R +  S++TD H  ++++ W+  P      Q    VNIT+ L K++E+ Y+ L+   + P+S AIYK       W+P+QF+S  C + +  P    +   + P     V  C        ++D    +   + FST+ GRPS   +  S  L EW+T T+L ISL R             L    + + + P  L ++      ++ +SD +VGGRCKCNGHA+ C  D   ++ C C HNT G +CERC   + DRPW R T + A+ C  C C   S++C F   +++ T   HGG C  C+ +T G  C+ C    Y
Sbjct:   30 GRPQRCLPVFENAAFGRLAQASHTCGSP-PEDFCPHV---GAAGAGAHCQRCDAADPQRHHNASYLTDFHS-QDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRP----EGQYLRPGEDERVAFCTS-----EFSDISPLSGGNVAFSTLEGRPSAYNFEESPGLQEWVTSTELLISLDR-------------LNTFGDDIFKDPKVLQSY------YYAVSDFSVGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRST--GHGGRCHHCRDHTAGPHCERCQENFY 372          
BLAST of Netrin 1 vs. Ensembl Human
Match: LAMA3 (laminin subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:6483])

HSP 1 Score: 165.622 bits (418), Expect = 1.262e-44
Identity = 118/402 (29.35%), Postives = 193/402 (48.01%), Query Frame = 2
Query:  119 PSFTNIIENVKAETTSTCGTNGP-------EQICRNWYDKTTAEAR-----QYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGT-LPDSIAIYKSLDFGVSWKPWQFFSQ---DCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGP--PWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEI-KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQ-----TRGQH--GGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            P++ N+ E  +   T+TCG  GP       E  C+     T   +      Q+C  C+++      +H     I  ++  W S PL      N VN+T+ L + F V YI ++   +  PD   + +S+DFG ++ PWQ+F+    DC + F      E N  +T  +  +VLCV   +  R       E V+  S I GRP      +S  L E+   T++R+  +R             L  H  S  Q  P +         ++ + D+++GG+C CNGHA  C I++ +++ +C+C H+T G+ C+RC + Y  R W+ A  + ++ C+ C C+ H+  C +   + +Q     T+G +  GGVC+ C+HNT G  C++CA  +YR    PV  P  C
Sbjct:   49 PTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPR--KAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFG----REANMAVTRDD--DVLCVTEYS--RIVPLENGEVVV--SLINGRPGAKNFTFSHTLREFTKATNIRLRFLR----------TNTLLGHLISKAQRDPTVTRR-----YYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGC 423          
BLAST of Netrin 1 vs. Ensembl Celegans
Match: unc-6 (Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34710])

HSP 1 Score: 262.692 bits (670), Expect = 5.306e-81
Identity = 145/395 (36.71%), Postives = 214/395 (54.18%), Query Frame = 2
Query:   83 PCYLN-GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCV--ELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            PC+ + GRP +C+P F N         + TCGTN P++ C    +      R+ C  CDA++  +S+P S +TD +   N TCW S P   +     V++T+SL K FE+ Y+++  C  LPDS+A+YKS DFG +W P+QF+S +C R F      + +  IT +N  E +C    +  P      G      PF  +  RPS   +     L +W+T TD+++   R +P+++      ELY  +  +  +  N  + + +    + + +LAVGGRCKCNGHA+RC+ D      CDC HNT G ECE CK  + DRPW RAT  +AN C  C C  H+ +C F   +++ +  + GGVCL C+HNT G  C  C     RD + P+TH +AC
Sbjct:   36 PCHDHTGRPVRCVPEFINAAFGKPVIASDTCGTNRPDKYC-TVKEGPDGIIREQCDTCDARNHFQSHPASLLTDLNSIGNMTCWVSTP---SLSPQNVSLTLSLGKKFELTYVSMHFCSRLPDSMALYKSADFGKTWTPFQFYSSECRRIFG----RDPDVSITKSNEQEAVCTASHIMGP------GGNRVAFPF--LENRPSAQNFENSPVLQDWVTATDIKVVFSRLSPDQA------ELYGLSNDV-NSYGNETDDEVKQRYFYSMGELAVGGRCKCNGHASRCIFDKMGRYTCDCKHNTAGTECEMCKPFHYDRPWGRATANSANSCVACNCNQHAKRCRFDAELFRLSGNRSGGVCLNCRHNTAGRNCHLCKPGFVRDTSLPMTHRKAC 407          
BLAST of Netrin 1 vs. Ensembl Celegans
Match: unc-6 (Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34710])

HSP 1 Score: 262.692 bits (670), Expect = 5.306e-81
Identity = 145/395 (36.71%), Postives = 214/395 (54.18%), Query Frame = 2
Query:   83 PCYLN-GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCV--ELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            PC+ + GRP +C+P F N         + TCGTN P++ C    +      R+ C  CDA++  +S+P S +TD +   N TCW S P   +     V++T+SL K FE+ Y+++  C  LPDS+A+YKS DFG +W P+QF+S +C R F      + +  IT +N  E +C    +  P      G      PF  +  RPS   +     L +W+T TD+++   R +P+++      ELY  +  +  +  N  + + +    + + +LAVGGRCKCNGHA+RC+ D      CDC HNT G ECE CK  + DRPW RAT  +AN C  C C  H+ +C F   +++ +  + GGVCL C+HNT G  C  C     RD + P+TH +AC
Sbjct:   36 PCHDHTGRPVRCVPEFINAAFGKPVIASDTCGTNRPDKYC-TVKEGPDGIIREQCDTCDARNHFQSHPASLLTDLNSIGNMTCWVSTP---SLSPQNVSLTLSLGKKFELTYVSMHFCSRLPDSMALYKSADFGKTWTPFQFYSSECRRIFG----RDPDVSITKSNEQEAVCTASHIMGP------GGNRVAFPF--LENRPSAQNFENSPVLQDWVTATDIKVVFSRLSPDQA------ELYGLSNDV-NSYGNETDDEVKQRYFYSMGELAVGGRCKCNGHASRCIFDKMGRYTCDCKHNTAGTECEMCKPFHYDRPWGRATANSANSCVACNCNQHAKRCRFDAELFRLSGNRSGGVCLNCRHNTAGRNCHLCKPGFVRDTSLPMTHRKAC 407          
BLAST of Netrin 1 vs. Ensembl Celegans
Match: lam-2 (Laminin-like protein lam-2 [Source:UniProtKB/Swiss-Prot;Acc:Q18823])

HSP 1 Score: 214.927 bits (546), Expect = 8.938e-61
Identity = 134/400 (33.50%), Postives = 198/400 (49.50%), Query Frame = 2
Query:   65 FESQSSPCYLNG--RPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHR--SYPPSHITDRHIPKNQTCWFSGPLQENPGQN---EVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCL----IDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYR 1210
            F +  +PCY     +PQ+C+P F N   N++ + T+TCGT  P + C           R  C  CD +H   S+P  ++TD ++  N+T W S  +QE  GQ      N+T+ L KSF++ Y+ L+     P+S  IYK       W+PWQF+S  C   + +       + I P N     C +      ++D        + FST+ GRPS   +  S+ L +W+T + +RISL R   F  E    P  L+  YY                        +SD AVGGRCKCNGHA+ C+    +D  + + C C HNT+G +C  C   Y DRPW+  T   AN C  C C   S++C F   ++++T   HGG C++C+ NT+G  C++C A H+R
Sbjct:   33 FGADGNPCYDRATRQPQRCVPDFVNAAFNLEVQVTNTCGTKRPTKFC---VQSGHTGQRSVCETCDDRHEGFSHPAKYLTDFNVGNNETWWQSDTMQE--GQQYPTTTNLTLVLGKSFDITYVRLKFISPRPESFTIYKKTHTDSEWEPWQFYSGSCRATYGLS----DRAPILPGNEATAQCTK-----EFSDISPITGGNIAFSTLEGRPSAHAFEESEVLQKWVTASAIRISLNRMNTFGDEVFKDPQVLRSYYY-----------------------AISDFAVGGRCKCNGHASECVGSSSVDGENRLVCRCEHNTQGADCNECLPFYNDRPWRSGTSVEANECIACNCSQLSNRCYFDQQLFEET--GHGGHCIDCQGNTQGVHCEQCIANHWR 393          
BLAST of Netrin 1 vs. Ensembl Celegans
Match: lam-3 (LAMinin related. See also lmb; Laminin alpha chain [Source:UniProtKB/TrEMBL;Acc:G5ECE3])

HSP 1 Score: 145.591 bits (366), Expect = 4.130e-37
Identity = 112/384 (29.17%), Postives = 175/384 (45.57%), Query Frame = 2
Query:  116 LPSFTNIIENVKAETTSTCGTNGPEQICR----NWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGT-LPDSIAIYKSLDFGVSWKPWQFFSQ---DCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHF-GLSDLAVGGRCKCNGHANRCLIDD-NDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYK-------QTRGQHGGVCLECKHNTEGHACDECAAFHYR 1210
             P+  N+  N     T TCG    E+ C+        KTT      C ICDA   H+ +P  +  D      +  W S  L       +VNIT+ L++ ++V YI L++  +  P +  + KSLD G  ++PWQ+++    +C R F +P T           +H   C    +     + G+  T L    + GRP     S   +E    T  R   +R    ++    L  +   ++SL          K+  + +F  +SD+++GG+C C GHA  C  D    + KC+C HNT G+ C RC   +   PW+  T  + NVC+ CQC+NH+  C++   + +       +   + GG CLEC HNTEG  C+ C   +YR
Sbjct:   49 FPNIFNLATNSLITATDTCGQYTAEEYCKLVEHVLLRKTTNTQSPQCDICDANNVHKRHPIEYAID----GTRRWWQSPSLANGLRFEKVNITIDLRQEYQVAYIILKMGNSPRPGTWVLEKSLD-GEYYEPWQYYAMQDAECMRQFGIPATTGVPRFQKEDEVH---CTSEYSKITPLENGEIHTSL----VNGRPGAENTS---LELQKFTRARFVRLRLISPRTLNADLMIINKKSDSL---------DKSVTMRYFYSISDISIGGQCICYGHAESCPSDPVTGQFKCECRHNTCGESCNRCCPLFNQLPWKPGTNSHPNVCQQCQCFNHAHSCVYDDELDRNKWSITPEGVYEGGGRCLECAHNTEGFNCERCKDGYYR 408          
BLAST of Netrin 1 vs. Ensembl Celegans
Match: lam-1 (LAMinin related. See also lmb [Source:UniProtKB/TrEMBL;Acc:V6CIX7])

HSP 1 Score: 142.895 bits (359), Expect = 3.655e-36
Identity = 109/410 (26.59%), Postives = 187/410 (45.61%), Query Frame = 2
Query:  101 RPQQCLPSFTNIIENVKAE--TTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK------HRSYPPSH-----ITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTE--PIVHFGLSDLAVGGRCKCNGHANRCL-ID------------DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            + + C P   N++   K++   TSTCG+ G ++ C   +     E +  C  CD++         Y  SH     +T+    KN+  W+     EN  QN V+I+  L+  F   ++ +      P ++ I +S DFG +W+ +++F+ DC  +F  P   E      P    +V+C       +Y+D                    P +   + +  ++   ++   +  E ST  ++  L ++   L     +L++++ E     ++ + ++ V G C C GHA+RC+ ID            D    +C+C HNTEG  CE+CK+ Y D PW+ A     N C+ C C  H+ +C F   +Y+ +    GGVC +C HNT+G  C++C  F YRD  + +  P  C
Sbjct:   33 QDRSCYPITGNLLIGRKSQLKATSTCGSQGRQRFCIVSH----LEEQTKCFYCDSRTEWKPQREPYRLSHRIENVVTEVMDDKNRN-WYQ---SENGAQN-VSISFDLEAEFHFTHLIMTFKSFRPAAMIIERSADFGKTWQVYRYFAYDCDSSF--PGIPEG----PPKKHTDVICTS-----QYSDVA------------------PSTGGEIVYKVISPHIVTENPYADEISTLLKITNLRFNFTKLHTLGDDLLDYRPEIDEKYYYAIYEIVVRGSCSCYGHASRCIPIDPHVSPNTVMERADIVHGRCECMHNTEGLNCEKCKAFYNDLPWRPAIGDEKNECRQCNCNRHALRCHFDRAVYESSGFVSGGVCDDCMHNTQGKNCEQCKPFFYRDPRRTIDDPHVC 404          
BLAST of Netrin 1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0308337)

HSP 1 Score: 263.077 bits (671), Expect = 1.327e-80
Identity = 151/411 (36.74%), Postives = 216/411 (52.55%), Query Frame = 2
Query:   83 PCYLNG-RPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQIC--GTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFT-PEKSTPYRLK-----ELYYHTESLPQAPPNLVNH----------KTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            PCY     P+ C+P F N   +     +STCG++G ++ C         +  + C  CD     RS+P   +TD +   N TCW S P+    G N V +T+SL K FE+ Y+ LQ+C     PDS+ IYKS D G+SW+P+QFFS  C R F  P            N HE  C ++  P          + + FST+ GRPS         L +W+T TD+R+   R   P+      L+     +L     S+P A     N+           +   +H+ +SD +VGGRCKCNGHA++C  D + ++ C+C HNT G++CERCK  + DRPW RAT + AN CK C C  H+ +C F+M +++ ++G  GGVC  C+H+T G  C +C    YRD TKP+TH + C
Sbjct:   39 PCYNKAHEPRACIPDFVNAAYDAPVVASSTCGSSGAQRYCE------YQDHERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPV-TGSGDN-VTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQSTGRH----NEHEARCSDVTRP--------LVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVC 429          
BLAST of Netrin 1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0073942)

HSP 1 Score: 262.692 bits (670), Expect = 7.666e-80
Identity = 151/411 (36.74%), Postives = 217/411 (52.80%), Query Frame = 2
Query:   83 PCYLNG-RPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQIC--GTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRF-TPEKSTPYRLK-----ELYYHTESLPQAPPNLVNHKTEPI----------VHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            PCY     P+ C+P F N   +     +STCG++G ++ C         +  + C  CD     RS+P   +TD +   N TCW S P+  + G N V +T+SL K FE+ Y+ LQ+C     PDS+ IYKS D G+SW+P+QFFS  C R F  P            N HE  C ++  P          + + FST+ GRPS         L +W+T TD+R+   R   P+      L+     +L     S+P A     N+    +          +H+ +SD +VGGRCKCNGHA++C  D + ++ C+C HNT G++CERCK  + DRPW RAT + AN CK C C  H+ +C F+M +++ ++G  GGVC  C+H+T G  C +C    YRD TKP+TH + C
Sbjct:   39 PCYNKAHEPRACIPDFVNAAYDAPVVASSTCGSSGAQRYCE------YQDHERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGS-GDN-VTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQSTGRH----NEHEARCSDVTRP--------LVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVC 429          
BLAST of Netrin 1 vs. Ensembl Fly
Match: NetA (gene:FBgn0015773 transcript:FBtr0346088)

HSP 1 Score: 262.692 bits (670), Expect = 7.666e-80
Identity = 151/411 (36.74%), Postives = 217/411 (52.80%), Query Frame = 2
Query:   83 PCYLNG-RPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQIC--GTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRF-TPEKSTPYRLK-----ELYYHTESLPQAPPNLVNHKTEPI----------VHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            PCY     P+ C+P F N   +     +STCG++G ++ C         +  + C  CD     RS+P   +TD +   N TCW S P+  + G N V +T+SL K FE+ Y+ LQ+C     PDS+ IYKS D G+SW+P+QFFS  C R F  P            N HE  C ++  P          + + FST+ GRPS         L +W+T TD+R+   R   P+      L+     +L     S+P A     N+    +          +H+ +SD +VGGRCKCNGHA++C  D + ++ C+C HNT G++CERCK  + DRPW RAT + AN CK C C  H+ +C F+M +++ ++G  GGVC  C+H+T G  C +C    YRD TKP+TH + C
Sbjct:   39 PCYNKAHEPRACIPDFVNAAYDAPVVASSTCGSSGAQRYCE------YQDHERSCHTCDMTDPLRSFPARSLTDLNNSNNVTCWRSEPVTGS-GDN-VTLTLSLGKKFELTYVILQLCPHAPRPDSMVIYKSTDHGLSWQPFQFFSSQCRRLFGRPARQSTGRH----NEHEARCSDVTRP--------LVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDPQALLSLEAGGATDLASGKYSVPLANGPAGNNIEANLGGDVATSGSGLHYAISDFSVGGRCKCNGHASKCSTDASGQLNCECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEIFRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYRDATKPLTHRKVC 429          
BLAST of Netrin 1 vs. Ensembl Fly
Match: LanB2 (gene:FBgn0267348 transcript:FBtr0345031)

HSP 1 Score: 199.134 bits (505), Expect = 2.924e-55
Identity = 127/381 (33.33%), Postives = 190/381 (49.87%), Query Frame = 2
Query:   98 GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQ-NEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYG-QAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCL----IDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAA-FHYRD 1213
            GRPQ+CLP F N    ++ E+T+TCG       C     +T  +  + C  C  K+  + PS +TD H P++ T W S  + E     N VN+T+ L KS+++ Y+ +      P+S  IYK       W P+QF+S  C   + +P +         A+    LC        Y+D     +  + FST+ GRPSG  +  S +L EW+T TD+RI+L R            EL+  ++ L                 + +SD+AVG RCKCNGHA++C+    +     + C+C HNT+G +C+RC   Y D  W+R+T    N CK C C   +DKC F   ++ +T   HGG CL+C+ N +G  C+ C   F+ RD
Sbjct:   62 GRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFCI----QTMNQNHKNCEFC--KYNDHNPSFLTDLHDPQSPTWWQSETMFEGIQHPNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAH---ALCTS-----EYSDISPLRDGEIAFSTLEGRPSGINFERSGELQEWVTATDIRITLDRLNTFGD------ELFGDSQVLKS-------------YFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRT--GHGGHCLDCRENRDGPNCERCKENFYMRD 407          
BLAST of Netrin 1 vs. Ensembl Fly
Match: LanB2 (gene:FBgn0267348 transcript:FBtr0076382)

HSP 1 Score: 199.134 bits (505), Expect = 2.924e-55
Identity = 127/381 (33.33%), Postives = 190/381 (49.87%), Query Frame = 2
Query:   98 GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQ-NEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYG-QAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCL----IDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAA-FHYRD 1213
            GRPQ+CLP F N    ++ E+T+TCG       C     +T  +  + C  C  K+  + PS +TD H P++ T W S  + E     N VN+T+ L KS+++ Y+ +      P+S  IYK       W P+QF+S  C   + +P +         A+    LC        Y+D     +  + FST+ GRPSG  +  S +L EW+T TD+RI+L R            EL+  ++ L                 + +SD+AVG RCKCNGHA++C+    +     + C+C HNT+G +C+RC   Y D  W+R+T    N CK C C   +DKC F   ++ +T   HGG CL+C+ N +G  C+ C   F+ RD
Sbjct:   62 GRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFCI----QTMNQNHKNCEFC--KYNDHNPSFLTDLHDPQSPTWWQSETMFEGIQHPNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAH---ALCTS-----EYSDISPLRDGEIAFSTLEGRPSGINFERSGELQEWVTATDIRITLDRLNTFGD------ELFGDSQVLKS-------------YFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRT--GHGGHCLDCRENRDGPNCERCKENFYMRD 407          
BLAST of Netrin 1 vs. Ensembl Zebrafish
Match: ntn2 (netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2])

HSP 1 Score: 275.404 bits (703), Expect = 8.816e-86
Identity = 151/395 (38.23%), Postives = 222/395 (56.20%), Query Frame = 2
Query:   77 SSPCYL-NGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            + PCY   G  ++C+P F N     +   +S CG   P     +  ++    A + C ICDA     ++P S++TD +   N TCW S  LQ +P    V +T+SL K FE+ Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C R +  P      + IT  N  E LC +       + Y  +  ++ FST+ GRPSG  +     L +W+T+TD+R+   R    ++ P   +E    +E    AP +L      P  ++ + D  VGGRCKCNGHA+RC+ + + ++ C+C HNTEG EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVC+ C+HNT G  C  C    YRD+ K +TH +AC
Sbjct:   23 TDPCYEETGAARRCIPEFINAAFGQEVSVSSVCGR--PVSRSCSLVERDDRPAVRTCQICDASDPRNAHPASYLTDLNSAHNLTCWQSENLQSSP--LNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGRTWTPYQFYSSQCRRMYNRP----NKAAITKQNEQEALCTD----GHTDLYPLSGGLIAFSTLDGRPSGKDFDSSPVLQDWVTVTDIRVVFSRPQHTRALPMSGRE----SEDALGAPGSL------PTYYYAVGDFQVGGRCKCNGHASRCVREKDGKLLCECKHNTEGPECDRCKPFHYDRPWQRATGKEANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGKAITHRRAC 395          
BLAST of Netrin 1 vs. Ensembl Zebrafish
Match: ntn2 (netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2])

HSP 1 Score: 275.018 bits (702), Expect = 1.456e-85
Identity = 151/395 (38.23%), Postives = 222/395 (56.20%), Query Frame = 2
Query:   77 SSPCYL-NGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            + PCY   G  ++C+P F N     +   +S CG   P     +  ++    A + C ICDA     ++P S++TD +   N TCW S  LQ +P    V +T+SL K FE+ Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C R +  P      + IT  N  E LC +       + Y  +  ++ FST+ GRPSG  +     L +W+T+TD+R+   R    ++ P   +E    +E    AP +L      P  ++ + D  VGGRCKCNGHA+RC+ + + ++ C+C HNTEG EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVC+ C+HNT G  C  C    YRD+ K +TH +AC
Sbjct:   32 TDPCYEETGAARRCIPEFINAAFGQEVSVSSVCGR--PVSRSCSLVERDDRPAVRTCQICDASDPRNAHPASYLTDLNSAHNLTCWQSENLQSSP--LNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGRTWTPYQFYSSQCRRMYNRP----NKAAITKQNEQEALCTD----GHTDLYPLSGGLIAFSTLDGRPSGKDFDSSPVLQDWVTVTDIRVVFSRPQHTRALPMSGRE----SEDALGAPGSL------PTYYYAVGDFQVGGRCKCNGHASRCVREKDGKLLCECKHNTEGPECDRCKPFHYDRPWQRATGKEANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGKAITHRRAC 404          
BLAST of Netrin 1 vs. Ensembl Zebrafish
Match: ntn1a (netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169])

HSP 1 Score: 270.011 bits (689), Expect = 1.987e-85
Identity = 153/406 (37.68%), Postives = 226/406 (55.67%), Query Frame = 2
Query:   62 IFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +F +Q+SP   CY  NG P++C+P F N     +   +STCG   P + C     +   E  + C  CDA    +++PP+++TD + P N TCW S    + P QN V +T+SL K FEV Y++LQ C   P+S+AI+KS+D+G SW P+Q++S  C + +  P+     + IT  N  E +C +       + +  +  ++ FST+ GRPS   +     L +W+T TD++++  R   F  E      L    Y                      + +SDL VGGRCKCNGHA+RC+ D +  + C+C HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   +YRD++KP++H +AC
Sbjct:   29 MFAAQTSPPDPCYDENGHPRRCIPDFVNAAFGKEVRASSTCGKT-PSRYC--VVTEKGDERHRNCHTCDASDPKKNHPPAYLTDLNNPHNLTCWQSDNYLQYP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKSWVPFQYYSTQCRKMYNKPS----KATITKQNEQEAICTD----SHTDMHPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASRCVKDRDGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKPISHRKAC 400          
BLAST of Netrin 1 vs. Ensembl Zebrafish
Match: ntn1a (netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169])

HSP 1 Score: 270.011 bits (689), Expect = 1.124e-83
Identity = 153/406 (37.68%), Postives = 226/406 (55.67%), Query Frame = 2
Query:   62 IFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +F +Q+SP   CY  NG P++C+P F N     +   +STCG   P + C     +   E  + C  CDA    +++PP+++TD + P N TCW S    + P QN V +T+SL K FEV Y++LQ C   P+S+AI+KS+D+G SW P+Q++S  C + +  P+     + IT  N  E +C +       + +  +  ++ FST+ GRPS   +     L +W+T TD++++  R   F  E      L    Y                      + +SDL VGGRCKCNGHA+RC+ D +  + C+C HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   +YRD++KP++H +AC
Sbjct:   29 MFAAQTSPPDPCYDENGHPRRCIPDFVNAAFGKEVRASSTCGKT-PSRYC--VVTEKGDERHRNCHTCDASDPKKNHPPAYLTDLNNPHNLTCWQSDNYLQYP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKSWVPFQYYSTQCRKMYNKPS----KATITKQNEQEAICTD----SHTDMHPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASRCVKDRDGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKPISHRKAC 400          
BLAST of Netrin 1 vs. Ensembl Zebrafish
Match: ntn1a (netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169])

HSP 1 Score: 270.011 bits (689), Expect = 1.124e-83
Identity = 153/406 (37.68%), Postives = 226/406 (55.67%), Query Frame = 2
Query:   62 IFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +F +Q+SP   CY  NG P++C+P F N     +   +STCG   P + C     +   E  + C  CDA    +++PP+++TD + P N TCW S    + P QN V +T+SL K FEV Y++LQ C   P+S+AI+KS+D+G SW P+Q++S  C + +  P+     + IT  N  E +C +       + +  +  ++ FST+ GRPS   +     L +W+T TD++++  R   F  E      L    Y                      + +SDL VGGRCKCNGHA+RC+ D +  + C+C HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   +YRD++KP++H +AC
Sbjct:   29 MFAAQTSPPDPCYDENGHPRRCIPDFVNAAFGKEVRASSTCGKT-PSRYC--VVTEKGDERHRNCHTCDASDPKKNHPPAYLTDLNNPHNLTCWQSDNYLQYP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKSWVPFQYYSTQCRKMYNKPS----KATITKQNEQEAICTD----SHTDMHPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASRCVKDRDGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKPISHRKAC 400          
BLAST of Netrin 1 vs. Ensembl Xenopus
Match: rps16 (ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-5786511])

HSP 1 Score: 261.536 bits (667), Expect = 9.700e-81
Identity = 152/415 (36.63%), Postives = 218/415 (52.53%), Query Frame = 2
Query:   47 HSVKVIFESQS------SPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTE------PIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            HS    F  Q        PCY  +G P++C+P F N   N + + +STCG                  A ++C   D + +SYP S++TD +   N TCW S     +  QN V++T+SL K FEV Y++LQ C   P+S+AI+KS+D+G SW P+Q++S  C + +  P+     + +T  N  E LC + +  E Y   G    ++ FST+ GRPS      S  L +W+T TD+R+   R                         P+L+ +K        P  ++ + +  VGGRCKCNGHA+RC  D    + CDC HNTEG EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C    YRD+++ +T  +AC
Sbjct:   22 HSTSSPFSGQQQQHSIPDPCYDEHGLPRRCVPEFVNAAFNKEVQASSTCGR----------------LATRHCDTTDPR-KSYPASYLTDLNTAGNMTCWRSETFPRHSSQN-VSLTLSLGKKFEVTYVSLQFCSPRPESVAIFKSMDYGKSWVPYQYYSSQCRKVYGKPS----RASVTKQNEQEALCTDGQT-ELYPLTG---GLIAFSTLDGRPSAQDLDNSPVLQDWLTATDIRVFFSR-------------------------PHLLGNKESEASDEGPGFYYSVGEFQVGGRCKCNGHASRCGKDKEARLICDCKHNTEGPECDRCKPFHYDRPWQRATAREANECMACTCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDVSRAITDRRAC 385          
BLAST of Netrin 1 vs. Ensembl Xenopus
Match: rps16 (ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-5786511])

HSP 1 Score: 261.151 bits (666), Expect = 2.806e-80
Identity = 155/435 (35.63%), Postives = 224/435 (51.49%), Query Frame = 2
Query:    2 IFIRTIAILNLSVWI-----HSVKVIFESQS------SPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTE------PIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
             ++R +  L L V       HS    F  Q        PCY  +G P++C+P F N   N + + +STCG                  A ++C   D + +SYP S++TD +   N TCW S     +  QN V++T+SL K FEV Y++LQ C   P+S+AI+KS+D+G SW P+Q++S  C + +  P+     + +T  N  E LC + +  E Y   G    ++ FST+ GRPS         L +W+T TD+R+   R                         P+L+ +K        P  ++ + +  VGGRCKCNGHA+RC  D    + CDC HNTEG EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C    YRD+++ +T  +AC
Sbjct:    2 FYLREMPHLFLLVSFFPMLPHSTSSPFSGQQQQHSIPDPCYDEHGLPRRCVPEFVNAAFNKEVQASSTCGR----------------LATRHCDTTDPR-KSYPASYLTDLNTAGNMTCWRSETFPRHSSQN-VSLTLSLGKKFEVTYVSLQFCSPRPESVAIFKSMDYGKSWVPYQYYSSQCRKVYGKPS----RASVTKQNEQEALCTDGQT-ELYPLTG---GLIAFSTLDGRPSAQDLDNSPVLQDWLTATDIRVFFSR-------------------------PHLLGNKESEASDEGPGFYYSVGEFQVGGRCKCNGHASRCGKDKEARLICDCKHNTEGPECDRCKPFHYDRPWQRATAREANECMACTCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDVSRAITDRRAC 385          
BLAST of Netrin 1 vs. Ensembl Xenopus
Match: ntn1 (netrin 1 [Source:NCBI gene;Acc:779839])

HSP 1 Score: 252.292 bits (643), Expect = 7.479e-77
Identity = 150/394 (38.07%), Postives = 212/394 (53.81%), Query Frame = 2
Query:   80 SPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGP--PWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
             PCY    RP+ C+P F N+    +  T++TCG   P+++C  + D T   +R+ C +CD K    SYPPS++TD      QTCW S      P    V +T+ L + FE+ Y +L+ C   PDS+AIYKS+D+G +W P+QF+S  C R +   TT    S I+    HE  C + +   +    G    ++ F  + GRPS     +S  L +W+T TD+R+   R    K    R K  +Y                       G+S++ VGGRCKCNGHA+RC     + + C+C HNT G EC+ CK  Y DRPWQRAT  NA+ C  C+C  HS +C F+M +YK +  + GGVCL C+HNT G  C  C   + RD++KP+T  +AC
Sbjct:   40 GPCYDAKQRPKYCIPDFINVALGQEVITSNTCGRT-PQKLC-YFLDSTNVTSRR-CQLCDQKRPENSYPPSYMTDTDA---QTCWKSESGITFP--QNVTLTLPLGRRFELVYASLRFCSPRPDSMAIYKSMDYGKTWIPFQFYSTHCRRVYDQATT----SAISKPMQHEATCTDFQTGVKPLTKG----LVAFMPLAGRPSARRFEYSPVLQDWVTATDIRVVFNRLHHGKKMGIRRKTAFY-----------------------GVSEIQVGGRCKCNGHASRCTAG-KEGLMCECQHNTIGPECDACKPFYYDRPWQRATPSNAHECVACECNLHSHRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKQGYKRDLSKPITSRKAC 393          
BLAST of Netrin 1 vs. Ensembl Xenopus
Match: utp4 (UTP4 small subunit processome component [Source:Xenbase;Acc:XB-GENE-977755])

HSP 1 Score: 187.578 bits (475), Expect = 5.340e-51
Identity = 128/397 (32.24%), Postives = 189/397 (47.61%), Query Frame = 2
Query:   86 CYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQ-NEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYG-QAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            CY  G PQ+C+P F N   N     T+TCGT  PE+ C            + C ICD+   H  +   ++TD +     T W S  +       + +N+T+ L K+F++ Y+ L+   + P+S A+YK       W P+Q++S  C + ++      +    T  +  + LC +      ++D        + FST+ GRPS   +     L EW+T TD+R++L R   F  E  S P  LK  YY                        +SD AVGGRCKCNGHA+ C+ ++ ++I C+C HNT G +CE+C   Y DRPW+R+T  + N C  C C   S +C F   +Y+ T   HGG C  C  NT+G  C+ C   +YR       H   C
Sbjct:   22 CYEEGSPQRCMPEFVNAAFNATVVATNTCGTP-PEEYC---VQTGVTGVTKSCHICDSGQFHLQHGAEYLTDYNNQAEITWWQSQTMLAGIQYPSTINLTLHLGKAFDITYVRLKFHTSRPESFALYKRTHEDGPWIPYQYYSGSCEKTYQKFN---RGFIRTGEDEQQALCTD-----EFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFSDPKVLKSYYY-----------------------AISDFAVGGRCKCNGHASECVRNEFEKIVCNCKHNTFGSDCEKCLPFYNDRPWRRSTADSPNECLPCNCNGRSQECYFDPELYRST--GHGGHCTGCADNTDGPNCERCRENYYRQDNNEPCHACQC 381          
BLAST of Netrin 1 vs. Ensembl Xenopus
Match: utp4 (UTP4 small subunit processome component [Source:Xenbase;Acc:XB-GENE-977755])

HSP 1 Score: 187.578 bits (475), Expect = 5.389e-51
Identity = 126/385 (32.73%), Postives = 187/385 (48.57%), Query Frame = 2
Query:   86 CYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQ-NEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYG-QAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYR 1210
            CY  G PQ+C+P F N   N     T+TCGT  PE+ C            + C ICD+   H  +   ++TD +     T W S  +       + +N+T+ L K+F++ Y+ L+   + P+S A+YK       W P+Q++S  C + ++      +    T  +  + LC +      ++D        + FST+ GRPS   +     L EW+T TD+R++L R   F  E  S P  LK  YY                        +SD AVGGRCKCNGHA+ C+ ++ ++I C+C HNT G +CE+C   Y DRPW+R+T  + N C  C C   S +C F   +Y+ T   HGG C  C  NT+G  C+ C   +YR
Sbjct:   19 CYEEGSPQRCMPEFVNAAFNATVVATNTCGTP-PEEYC---VQTGVTGVTKSCHICDSGQFHLQHGAEYLTDYNNQAEITWWQSQTMLAGIQYPSTINLTLHLGKAFDITYVRLKFHTSRPESFALYKRTHEDGPWIPYQYYSGSCEKTYQKFN---RGFIRTGEDEQQALCTD-----EFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFSDPKVLKSYYY-----------------------AISDFAVGGRCKCNGHASECVRNEFEKIVCNCKHNTFGSDCEKCLPFYNDRPWRRSTADSPNECLPCNCNGRSQECYFDPELYRST--GHGGHCTGCADNTDGPNCERCRENYYR 366          

HSP 2 Score: 50.0618 bits (118), Expect = 8.925e-6
Identity = 37/117 (31.62%), Postives = 52/117 (44.44%), Query Frame = 2
Query:  896 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            C CNGH++ C   D +   CDC HNT G  CERC   Y    +  +T  +A+ C+ C C   S     S  +  +T+     VC  C   T G  C+ C   ++ D       P+ C
Sbjct:  702 CTCNGHSDTC---DPESGVCDCQHNTAGPHCERCSEGY----YGDSTTGSASDCQPCPCPGGS-----SCAVVPRTKEV---VCTNCPLGTTGKRCELCDDGYFGDPLGENGAPRPC 803          
BLAST of Netrin 1 vs. Ensembl Mouse
Match: Ntn1 (netrin 1 [Source:MGI Symbol;Acc:MGI:105088])

HSP 1 Score: 269.24 bits (687), Expect = 2.371e-83
Identity = 153/400 (38.25%), Postives = 216/400 (54.00%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +Q  PC   NG P++C+P F N         +STCG   P + C     +   E  + C +C++    +++PP+ +TD + P N TCW S    + P  + V +T+SL K FEV Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C + +  P      + IT  N  E +C +     R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R   F  E      L    Y+                     + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C    YRD+ KP+TH +AC
Sbjct:   36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYY---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKAC 401          
BLAST of Netrin 1 vs. Ensembl Mouse
Match: Ntn1 (netrin 1 [Source:MGI Symbol;Acc:MGI:105088])

HSP 1 Score: 269.24 bits (687), Expect = 2.371e-83
Identity = 153/400 (38.25%), Postives = 216/400 (54.00%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +Q  PC   NG P++C+P F N         +STCG   P + C     +   E  + C +C++    +++PP+ +TD + P N TCW S    + P  + V +T+SL K FEV Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C + +  P      + IT  N  E +C +     R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R   F  E      L    Y+                     + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C    YRD+ KP+TH +AC
Sbjct:   36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYY---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKAC 401          
BLAST of Netrin 1 vs. Ensembl Mouse
Match: Ntn3 (netrin 3 [Source:MGI Symbol;Acc:MGI:1341188])

HSP 1 Score: 218.009 bits (554), Expect = 3.619e-64
Identity = 138/414 (33.33%), Postives = 195/414 (47.10%), Query Frame = 2
Query:   23 ILNLSVWIHSVKVIFESQSSPCYLNGR-PQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAF-KMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +L       ++     + + PCY   R P+ C+P   N     +   +STCG                   R    +CD+    R++    +T      +  CW S  LQ+ P    V +TV L K+FE+ +++L+ C   P S+A+ KS D G SW P  FFS  C   + ++P   +  S   P    E LC    AP+   D G    +L FS   G P G     S  L +W+T TD+RI L R   +  T      + Y                      +  ++L VGGRCKCNGHA+RCL+D +  + CDC H TEG +C RCK  Y DRPWQRAT Q A+ C  C C  H+ +C F+M +Y+ +  + GGVCL C+HNT G  C  C    YRD  + ++  +AC
Sbjct:    9 LLTAGTLSAALSPGLPASADPCYDEAREPRSCIPGLVNAALGREVLASSTCG-------------------RSANRVCDSSDPQRAHSADLLTSAPGTASPLCWRSDLLQQAP--FNVTLTVPLGKAFELVFVSLRFCSAPPTSVALLKSQDHGRSWVPLGFFSSSCTLDYGRLPAPADGPSGPGP----EALC--FPAPQAQPDGGG---LLAFSVQDGSPQGLDLDNSPVLQDWVTATDIRIVLTRPAIQGDTRDGGVTVPYS---------------------YSATELQVGGRCKCNGHASRCLLDTHGHLVCDCQHGTEGPDCSRCKPFYCDRPWQRATGQEAHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRVLSDRRAC 371          
BLAST of Netrin 1 vs. Ensembl Mouse
Match: Lamc3 (laminin gamma 3 [Source:MGI Symbol;Acc:MGI:1344394])

HSP 1 Score: 195.667 bits (496), Expect = 8.130e-54
Identity = 130/406 (32.02%), Postives = 192/406 (47.29%), Query Frame = 2
Query:   23 ILNLSVWIHSVKVIFESQSSPCYLN-GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQ--NEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEV-LCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYR 1210
            + ++++ I        +    CY   GR Q+CLP F N     +AE + TCG   PE  C +          Q C   D   R +  S++TD H P + T W+  P      Q    VN+T+SL K++E+ Y+ L+   + P+S AIYK       W+P+Q++S  C + +  P    +   + P     V  C        ++D        + FST+ GRPS   + +   L EW+T TD+ ISL R   F  +     R+ + YY                      + +SD +VGGRCKCNGHA+ C  +   ++ C C HNT G +CERC   + DRPW R T ++AN C  C C  HS++C F   +Y+ T   HGG C  C+ +T G  C+ C   +YR
Sbjct:   13 VASMALVIQETHFAAGADMGSCYDGVGRAQRCLPEFENAAFGRRAEASHTCG-RPPEDFCPHVGAPGAGLQCQRCDDADPGRR-HDASYLTDFHSPDDST-WWQSPSMAFGVQYPTSVNLTLSLGKAYEITYVRLKFHTSRPESFAIYKRTYASGPWEPYQYYSASCQKTYGRP----EGHYLRPGEDERVAFCTS-----EFSDISPLNGGNVAFSTLEGRPSAYNFEESPVLQEWVTSTDILISLDRLNTFGDDIFKDPRVLQSYY----------------------YAVSDFSVGGRCKCNGHASECEPNAAGQLACRCQHNTTGVDCERCLPFFQDRPWARGTAEDANECLPCNCSGHSEECTFDRELYRST--GHGGHCQRCRDHTTGPHCERCEKNYYR 382          
BLAST of Netrin 1 vs. Ensembl Mouse
Match: Lamc3 (laminin gamma 3 [Source:MGI Symbol;Acc:MGI:1344394])

HSP 1 Score: 195.282 bits (495), Expect = 9.467e-54
Identity = 130/406 (32.02%), Postives = 192/406 (47.29%), Query Frame = 2
Query:   23 ILNLSVWIHSVKVIFESQSSPCYLN-GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQ--NEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEV-LCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYR 1210
            + ++++ I        +    CY   GR Q+CLP F N     +AE + TCG   PE  C +          Q C   D   R +  S++TD H P + T W+  P      Q    VN+T+SL K++E+ Y+ L+   + P+S AIYK       W+P+Q++S  C + +  P    +   + P     V  C        ++D        + FST+ GRPS   + +   L EW+T TD+ ISL R   F  +     R+ + YY                      + +SD +VGGRCKCNGHA+ C  +   ++ C C HNT G +CERC   + DRPW R T ++AN C  C C  HS++C F   +Y+ T   HGG C  C+ +T G  C+ C   +YR
Sbjct:   13 VASMALVIQETHFAAGADMGSCYDGVGRAQRCLPEFENAAFGRRAEASHTCG-RPPEDFCPHVGAPGAGLQCQRCDDADPGRR-HDASYLTDFHSPDDST-WWQSPSMAFGVQYPTSVNLTLSLGKAYEITYVRLKFHTSRPESFAIYKRTYASGPWEPYQYYSASCQKTYGRP----EGHYLRPGEDERVAFCTS-----EFSDISPLNGGNVAFSTLEGRPSAYNFEESPVLQEWVTSTDILISLDRLNTFGDDIFKDPRVLQSYY----------------------YAVSDFSVGGRCKCNGHASECEPNAAGQLACRCQHNTTGVDCERCLPFFQDRPWARGTAEDANECLPCNCSGHSEECTFDRELYRST--GHGGHCQRCRDHTTGPHCERCEKNYYR 382          
BLAST of Netrin 1 vs. UniProt/SwissProt
Match: sp|Q90922|NET1_CHICK (Netrin-1 OS=Gallus gallus OX=9031 GN=NTN1 PE=1 SV=1)

HSP 1 Score: 272.322 bits (695), Expect = 1.024e-83
Identity = 153/404 (37.87%), Postives = 222/404 (54.95%), Query Frame = 2
Query:   59 VIFESQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
             +  +Q  PCY  +G P++C+P F N     + + +STCG   P + C     +   E  + C +C+A    R++PPS +TD + P N TCW S    + P  + V +T+SL K FEV Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C + +  P+     + IT  N  E +C +     R    G    ++ FST+ GRP+   +     L +W+T TD++++  R   F  E      L    Y                      + +SDL VGGRCKCNGHA+RC+ D +D + CDC HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C    YRD++KP++H +AC
Sbjct:   34 AVQTAQPDPCYDEHGLPRRCIPDFVNSAFGKEVKVSSTCG-KPPSRYC--VVTEKGEEQVRSCHLCNASDPKRAHPPSFLTDLNNPHNLTCWQSDSYVQYP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCRKMYNKPS----RAAITKQNEQEAICTDSHTDVRPLSGG----LIAFSTLDGRPTAHDFDNSPVLQDWVTATDIKVTFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASRCVRDRDDNLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKAC 403          
BLAST of Netrin 1 vs. UniProt/SwissProt
Match: sp|O95631|NET1_HUMAN (Netrin-1 OS=Homo sapiens OX=9606 GN=NTN1 PE=1 SV=2)

HSP 1 Score: 270.781 bits (691), Expect = 4.178e-83
Identity = 154/400 (38.50%), Postives = 216/400 (54.00%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +Q  PC   NG P++C+P F N         +STCG   P + C     +   E  + C +C+A    +++PP+ +TD + P N TCW S    + P  + V +T+SL K FEV Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C + +  P      + IT  N  E +C +     R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R   F  E      L    Y                      + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   +YRD+ KP+TH +AC
Sbjct:   36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKAC 401          
BLAST of Netrin 1 vs. UniProt/SwissProt
Match: sp|Q2HXW4|NET1_PIG (Netrin-1 OS=Sus scrofa OX=9823 GN=NTN1 PE=2 SV=1)

HSP 1 Score: 269.626 bits (688), Expect = 8.974e-83
Identity = 153/400 (38.25%), Postives = 216/400 (54.00%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +Q  PC   NG P++C+P F N         +STCG   P + C     +   E  + C +C+A    +++PP+ +TD + P N TCW S    + P  + V +T+SL K FEV Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C + +  P      + IT  N  E +C +     R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R   F  E      L    Y                      + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   ++RD+ KP+TH +AC
Sbjct:   36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYFRDLGKPITHRKAC 401          
BLAST of Netrin 1 vs. UniProt/SwissProt
Match: sp|Q924Z9|NET1_RAT (Netrin-1 OS=Rattus norvegicus OX=10116 GN=Ntn1 PE=1 SV=1)

HSP 1 Score: 269.626 bits (688), Expect = 1.286e-82
Identity = 153/400 (38.25%), Postives = 216/400 (54.00%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +Q  PC   NG P++C+P F N         +STCG   P + C     +   E  + C +C++    +++PP+ +TD + P N TCW S    + P  + V +T+SL K FEV Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C + +  P      + IT  N  E +C +     R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R   F  E      L    Y+                     + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C    YRD+ KP+TH +AC
Sbjct:   36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYY---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKAC 401          
BLAST of Netrin 1 vs. UniProt/SwissProt
Match: sp|O09118|NET1_MOUSE (Netrin-1 OS=Mus musculus OX=10090 GN=Ntn1 PE=1 SV=3)

HSP 1 Score: 269.24 bits (687), Expect = 1.658e-82
Identity = 153/400 (38.25%), Postives = 216/400 (54.00%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +Q  PC   NG P++C+P F N         +STCG   P + C     +   E  + C +C++    +++PP+ +TD + P N TCW S    + P  + V +T+SL K FEV Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C + +  P      + IT  N  E +C +     R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R   F  E      L    Y+                     + +SDL VGGRCKCNGHA RC+ D +D + CDC HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C    YRD+ KP+TH +AC
Sbjct:   36 AQPDPCSDENGHPRRCIPDFVNAAFGKDVRVSSTCG-RPPARYC--VVSERGEERLRSCHLCNSSDPKKAHPPAFLTDLNNPHNLTCWQSENYLQFP--HNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRP----HRAPITKQNEQEAVCTDSHTDMRPLSGG----LIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYY---------------------YAVSDLQVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDMGKPITHRKAC 401          
BLAST of Netrin 1 vs. TrEMBL
Match: Q49BF8 (Netrin 2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 882.478 bits (2279), Expect = 0.000e+0
Identity = 426/456 (93.42%), Postives = 427/456 (93.64%), Query Frame = 2
Query:    2 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTNSWHR*VKAQSTR*YY*LRTVN*PIKIESGCKCHTIGSIK 1369
            IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACT+                             CKCHTIGSIK
Sbjct:    1 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTS-----------------------------CKCHTIGSIK 427          
BLAST of Netrin 1 vs. TrEMBL
Match: E1CHK4 (Netrin OS=Dugesia japonica OX=6161 GN=DjnetB PE=2 SV=1)

HSP 1 Score: 710.294 bits (1832), Expect = 0.000e+0
Identity = 339/456 (74.34%), Postives = 377/456 (82.68%), Query Frame = 2
Query:    2 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTNSWHR*VKAQSTR*YY*LRTVN*PIKIESGCKCHTIGSIK 1369
            +FI+T  ILNLSVWIHSVKVI+ESQ+S CY NG+PQQCLPSFTNIIE+VK ETTSTCGTNGPEQICRNWYD++T EARQYCSICDAKHRSYPP H+TDRHIP NQTCWFSGPLQE  GQNEVNITV+LKKSFEVYY+ALQICGTLPDSIAIYKSLDFGV+W+PWQFFSQDCYRAFKMPTTNEQNSQITP NI EVLCVELKAP+RYND+GQAETVLPFST  GRPSGPPWSQ L+EWMTMT+L+ISLMRF P KSTP R KEL+YHTE+LP   PN +N+K+EPIVHFGLSDLAVGGRCKCNGHA+RCLIDDNDEI+CDCHHNTEGQ+CERCKSNYLDRPW RATRQNANVCK C C  HS +C F+  +Y +    +GGVC+ C+HNT G+ C+ C   +YR+ TKP  H  AC +                             CKCHTIGSIK
Sbjct:    1 MFIKTFVILNLSVWIHSVKVIYESQTSSCYSNGKPQQCLPSFTNIIEDVKVETTSTCGTNGPEQICRNWYDRSTTEARQYCSICDAKHRSYPPLHLTDRHIPNNQTCWFSGPLQEVSGQNEVNITVALKKSFEVYYVALQICGTLPDSIAIYKSLDFGVTWRPWQFFSQDCYRAFKMPTTNEQNSQITPTNIQEVLCVELKAPDRYNDFGQAETVLPFSTTVGRPSGPPWSQSLIEWMTMTNLKISLMRFPPVKSTPDRYKELFYHTETLPHGLPNSINYKSEPIVHFGLSDLAVGGRCKCNGHASRCLIDDNDEIRCDCHHNTEGQDCERCKSNYLDRPWHRATRQNANVCKYCDCNLHSYRCNFNHQLYVKNNFTNGGVCINCQHNTTGNNCEICQNGYYRNWTKPQEHRSACIS-----------------------------CKCHTIGSIK 427          
BLAST of Netrin 1 vs. TrEMBL
Match: A0A5K4ERQ7 (Putative netrin OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 389.423 bits (999), Expect = 5.284e-128
Identity = 212/460 (46.09%), Postives = 275/460 (59.78%), Query Frame = 2
Query:   50 SVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGT-NGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAP--------------PNLVNHKTEPI-----------------------------VHFGLSDLAVGGRCKCNGHANRCLID---------DNDE--------IKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            ++KVI+E+  S CY  G+  +C P FTNI E+V  + TSTCG  +  E+ICR           + C  C  K   +    +TDRH   N+TCW SG +   PG + VN+T+SL K FEVYYI+LQ CG LPDSIA+YKS DFGV+WKPWQ+FS DCYRAF +PT+NE N+QI+ ANI EVLCV LK+P+ + + GQ+  V+ FST  GRPS  PWS  L++WMTMTDLRISLMRF PE    YR  E+ Y +  L   P              P++    T P+                             VHF  SDL++GGRCKCNGHANRC+ D         DN+         ++CDC HNTEG +CERC   YLDRPW R T ++AN CK CQC NH+++C+FS+  +K++ G  GG+CL C+H+TEG  CD+C   +YRD    + +  AC
Sbjct:   42 NIKVIYEATRSVCYTKGQAIECSPPFTNIAESVDIKATSTCGQFDQSEEICR------YVMGHEKCETC-GKGEKFGTHLLTDRHQMNNETCWVSGSVL--PG-DTVNLTLSLGKRFEVYYISLQPCGQLPDSIALYKSSDFGVTWKPWQYFSTDCYRAFHLPTSNEHNAQISLANIQEVLCVALKSPDVHGNSGQSSNVIAFSTTIGRPSMQPWSSALIDWMTMTDLRISLMRF-PE----YR-DEVQYDSNGLFLNPSFLKPTNVFRVSGSPSIGGFGTNPVLSEAGTLDMSQHLYQSDMHYSKTPKSKTPVHFSFSDLSIGGRCKCNGHANRCIRDRIVGTGITTDNNGQTKSQWGPLRCDCQHNTEGADCERCSPGYLDRPWARGTSESANDCKPCQCGNHTNQCIFSVKAFKRSGGITGGICLACQHHTEGSNCDQCIIGYYRDPNLTMGNEHAC 485          
BLAST of Netrin 1 vs. TrEMBL
Match: G4VQH8 (Putative netrin OS=Schistosoma mansoni OX=6183 GN=Smp_151310 PE=4 SV=1)

HSP 1 Score: 395.971 bits (1016), Expect = 6.122e-127
Identity = 211/431 (48.96%), Postives = 273/431 (63.34%), Query Frame = 2
Query:   50 SVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGT-NGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNL--------------VNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID---------DNDE--------IKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            ++KVI+E+  S CY  G+  +C P FTNI E+V  + TSTCG  +  E+ICR           + C  C  K   +    +TDRH   N+TCW SG +   PG + VN+T+SL K FEVYYI+LQ CG LPDSIA+YKS DFGV+WKPWQ+FS DCYRAF +PT+NE N+QI+ ANI EVLCV LK+P+ + + GQ+  V+ FST  GRPS  PWS  L++WMTMTDLRISLMRF PE    YR  E+ Y +  L   P  L                 K++  VHF  SDL++GGRCKCNGHANRC+ D         DN+         ++CDC HNTEG +CERC   YLDRPW R T ++AN CK CQC NH+++C+FS+  +K++ G  GG+CL C+H+TEG  CD+C   +YRD    + +  AC
Sbjct:   42 NIKVIYEATRSVCYTKGQAIECSPPFTNIAESVDIKATSTCGQFDQSEEICR------YVMGHEKCETC-GKGEKFGTHLLTDRHQMNNETCWVSGSVL--PG-DTVNLTLSLGKRFEVYYISLQPCGQLPDSIALYKSSDFGVTWKPWQYFSTDCYRAFHLPTSNEHNAQISLANIQEVLCVALKSPDVHGNSGQSSNVIAFSTTIGRPSMQPWSSALIDWMTMTDLRISLMRF-PE----YR-DEVQYDSNGLFLNPRTLDMSQHLYQSDMHYSKTPKSKTPVHFSFSDLSIGGRCKCNGHANRCIRDRIVGTGITTDNNGQTKSQWGPLRCDCQHNTEGADCERCSPGYLDRPWARGTSESANDCKPCQCGNHTNQCIFSVKAFKRSGGITGGICLACQHHTEGSNCDQCIIGYYRDPNLTMGNEHAC 456          
BLAST of Netrin 1 vs. TrEMBL
Match: A0A4Z2D9H4 (Netrin-A OS=Schistosoma japonicum OX=6182 GN=EWB00_003107 PE=4 SV=1)

HSP 1 Score: 394.045 bits (1011), Expect = 1.182e-125
Identity = 218/500 (43.60%), Postives = 281/500 (56.20%), Query Frame = 2
Query:   50 SVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNG-PEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAP--------------PNLVNHKTEPI-----------------------------VHFGLSDLAVGGRCKCNGHANRCLID---------DND--------EIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTNSWHR*VKAQSTR*YY*LRTVN*PIKIESGCKCHTIGSI 1366
            +VKVI+E+  S CY  G+  +C P FTNI E++  + TSTCG  G  E+ICR          ++ C ICD+  + +    +TDRH   N+TCW SG +   PG + VN+T+SL K FEVYYI+LQ CG LPDSIA+YKS DFG++WKPWQ+FS DCYRAF++PT+NE N+QI+ ANI EVLCV LK+P+ ++  G++  ++ FST  GRPS  PWS  L++WMTMTDLRISLMRF      P   +E+ + +  L   P              PN+      P                              VHF  SDL++GGRCKCNGHANRC+ D         +ND         ++CDC HNTEG +CERC S YLDRPW R T ++AN CK C C  HS+ C+FS  +Y  +    GGVC +C+HNT G  C  CA  +YRD TKPV+H Q C                               C+CH IGSI
Sbjct:   42 NVKVIYEATRSVCYTKGQAIECSPPFTNIAESIDIKATSTCGQFGQSEEICR------YVLGQRKCDICDSSEK-FGTHLLTDRHQMNNETCWISGSVL--PG-DTVNLTLSLGKRFEVYYISLQPCGQLPDSIALYKSSDFGITWKPWQYFSTDCYRAFRLPTSNEHNAQISLANIQEVLCVALKSPDIHDAIGKSSNIIAFSTTIGRPSTQPWSSALIDWMTMTDLRISLMRF------PEHREEVQHDSNGLFLNPGLLKPSKVFRVSGSPNIGGFGINPALSETGALDMSQHLYQSDMHYAKTPNSKSPVHFSFSDLSIGGRCKCNGHANRCVRDRIVSTSSTKENDGLAKSQWGPLRCDCQHNTEGTDCERCSSGYLDRPWARGTSESANECKRCDCNLHSNSCIFSNQLYLMSMKVSGGVCQDCQHNTVGRRCHNCATGYYRDWTKPVSHDQVCLE-----------------------------CRCHPIGSI 496          
BLAST of Netrin 1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029])

HSP 1 Score: 277.715 bits (709), Expect = 6.673e-87
Identity = 157/401 (39.15%), Postives = 220/401 (54.86%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID-DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTNS 1255
            S   PCY  +G  ++C+P F N     +   +STCG  GP + C    DK    AR  C  CDA    R++P S++TD + P N TCW S        Q  V +T+SL K FEV Y+++Q C   PDS+AI+KS+D+G +W P+QF+S  C + F  P      + IT  N  E +C +  A  R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R T                   P  P      + E  + + +SDL VGGRCKCNGHA+RC+ + D   + CDC HNT G EC+RCK  + DRPWQRAT + A+ C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   +YRD++KP++H +AC  +
Sbjct:  209 SSPDPCYDEHGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQ--DKGEEGART-CHTCDASDPKRAHPGSYLTDLNNPHNLTCWQS-ETGVQALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRP----NRAAITKQNEQEAVCTDAHADGRPLSGG----LVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRLT------------------APGEP-----DEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKACKGT 574          
BLAST of Netrin 1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029])

HSP 1 Score: 276.559 bits (706), Expect = 2.229e-86
Identity = 157/398 (39.45%), Postives = 219/398 (55.03%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID-DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            S   PCY  +G  ++C+P F N     +   +STCG  GP + C    DK    AR  C  CDA    R++P S++TD + P N TCW S        Q  V +T+SL K FEV Y+++Q C   PDS+AI+KS+D+G +W P+QF+S  C + F  P      + IT  N  E +C +  A  R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R T                   P  P      + E  + + +SDL VGGRCKCNGHA+RC+ + D   + CDC HNT G EC+RCK  + DRPWQRAT + A+ C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   +YRD++KP++H +AC
Sbjct:   32 SSPDPCYDEHGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQ--DKGEEGART-CHTCDASDPKRAHPGSYLTDLNNPHNLTCWQS-ETGVQALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRPN----RAAITKQNEQEAVCTDAHADGRPLSGG----LVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRLT------------------APGEP-----DEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKAC 394          
BLAST of Netrin 1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029])

HSP 1 Score: 277.715 bits (709), Expect = 1.357e-85
Identity = 157/398 (39.45%), Postives = 219/398 (55.03%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID-DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            S   PCY  +G  ++C+P F N     +   +STCG  GP + C    DK    AR  C  CDA    R++P S++TD + P N TCW S        Q  V +T+SL K FEV Y+++Q C   PDS+AI+KS+D+G +W P+QF+S  C + F  P      + IT  N  E +C +  A  R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R T                   P  P      + E  + + +SDL VGGRCKCNGHA+RC+ + D   + CDC HNT G EC+RCK  + DRPWQRAT + A+ C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   +YRD++KP++H +AC
Sbjct:  209 SSPDPCYDEHGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQ--DKGEEGART-CHTCDASDPKRAHPGSYLTDLNNPHNLTCWQS-ETGVQALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRP----NRAAITKQNEQEAVCTDAHADGRPLSGG----LVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRLT------------------APGEP-----DEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKAC 571          
BLAST of Netrin 1 vs. Ensembl Cavefish
Match: ntn1b (netrin-1-like [Source:NCBI gene;Acc:111191060])

HSP 1 Score: 273.478 bits (698), Expect = 1.966e-85
Identity = 157/407 (38.57%), Postives = 224/407 (55.04%), Query Frame = 2
Query:   62 IFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID-DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            +F +QSSP   CY  NG+P++C+P F N     +   +STCG     + C     +   E  + C  CDA    +++P +++TD + P N TCW S    ++P QN V +T+SL K FEV Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C + F  P+     + IT  N  E +C +     R      A  ++ FST+ GRPS   +     L +W+T TD+R++  R   F  E      L    Y                      + +SDL VGGRCKCNGHA++C+ D D   + C+C HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   +YRD+TK ++H +AC
Sbjct:   46 VFAAQSSPPDPCYDENGQPRRCIPDFVNAAFGKEVRASSTCGAQTAARYC--VVTERGEERSRECHTCDAADPKKAHPAAYLTDLNNPHNLTCWQSESYVQHP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGKTWVPFQFYSTQCKKMFNRPS----RAAITKQNEQEAVCTDSHTDMR----PLAGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRLHTFGDENEDDSELARDSYF---------------------YAVSDLQVGGRCKCNGHASKCVKDRDGGGLVCECKHNTAGAECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMTKAISHRRAC 419          
BLAST of Netrin 1 vs. Ensembl Cavefish
Match: NTN1 (netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029])

HSP 1 Score: 276.559 bits (706), Expect = 1.027e-84
Identity = 157/398 (39.45%), Postives = 219/398 (55.03%), Query Frame = 2
Query:   71 SQSSPCY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLID-DNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            S   PCY  +G  ++C+P F N     +   +STCG  GP + C    DK    AR  C  CDA    R++P S++TD + P N TCW S        Q  V +T+SL K FEV Y+++Q C   PDS+AI+KS+D+G +W P+QF+S  C + F  P      + IT  N  E +C +  A  R    G    ++ FST+ GRPS   +     L +W+T TD+R++  R T                   P  P      + E  + + +SDL VGGRCKCNGHA+RC+ + D   + CDC HNT G EC+RCK  + DRPWQRAT + A+ C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C   +YRD++KP++H +AC
Sbjct:  209 SSPDPCYDEHGAARRCIPDFVNAAFGKEVRASSTCGLKGPSRYCAQ--DKGEEGART-CHTCDASDPKRAHPGSYLTDLNNPHNLTCWQS-ETGVQALQGNVTLTLSLGKKFEVTYVSVQFCSKRPDSMAIFKSMDYGKTWVPFQFYSTQCRKVFNRP----NRAAITKQNEQEAVCTDAHADGRPLSGG----LVAFSTLDGRPSAHDFDNSPVLQDWVTATDVRVTFSRLT------------------APGEP-----DEDEDSLFYAVSDLQVGGRCKCNGHASRCVKERDTGGLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREAHECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDLSKPISHRKAC 571          
BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009682.1 (pep scaffold:Pmarinus_7.0:GL479835:738:11671:-1 gene:ENSPMAG00000008750.1 transcript:ENSPMAT00000009682.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 157.918 bits (398), Expect = 1.060e-44
Identity = 93/279 (33.33%), Postives = 139/279 (49.82%), Query Frame = 2
Query:  389 KSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEV--LCVELKAPERYNDYGQ-AETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYR 1210
            K+F++ Y+ L+   + P+S AIYK       W P+Q++S  C      PT  ++N     +   E   LC +      ++D        + FST+ GRPS   +     L +W+T T++R++L R        +                    +HK     ++ +SD AVGGRCKCNGHA+ C+ ++   + C C HNT G +CE+C   Y DRPW RAT ++AN C LC C   +D+C F   +Y+ T   HGG C  C+ NT+G  C+ C    YR
Sbjct:    2 KAFDITYVRLKFHTSRPESFAIYKRASMDGPWTPYQYYSGSC-----EPTYGKRNRGFLRSGDDEQTPLCTD-----EFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQDWVTSTEIRVTLNRLNTFGDEVFN-------------------DHKVLRSYYYAISDFAVGGRCKCNGHASECVKNELGALACKCRHNTMGADCEKCLPLYNDRPWHRATSESANECTLCDCNGRADECYFDPELYRAT--GHGGHCTNCRDNTDGKTCERCLENFYR 249          
BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004606.1 (pep scaffold:Pmarinus_7.0:GL477874:5526:15188:-1 gene:ENSPMAG00000004198.1 transcript:ENSPMAT00000004606.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 113.235 bits (282), Expect = 1.603e-29
Identity = 75/231 (32.47%), Postives = 110/231 (47.62%), Query Frame = 2
Query:  389 KSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHE--VLCVELKAPERYNDYGQAETV-LPFSTIYGRPSGPPWSQD---LVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNAN 1051
            K+F++ Y+ L+   + P+S AIYK       W+P+QF+S  C R F +P+          A   E   LC +      ++D        + FST+ GRP    +  +     EW+T TD+R+SL R   F  E    P  L+  YY                        +SDLAVGGRCKC+GHA+ C    +  + C C HNT G +CERC  ++  RPW +A+  +A+
Sbjct:    4 KAFQITYVRLRFHTSRPESFAIYKRTSPASPWQPYQFYSGTCERTFGLPSRG-----FLRAGDEERTALCSD-----EFSDISPLTGGNVAFSTLEGRPGALAFDGNDKLQQEWVTATDVRVSLRRLNTFGDEVFGDPKVLRSYYY-----------------------AVSDLAVGGRCKCHGHASECGRGSDGRLVCRCQHNTTGDDCERCLPSHNSRPWAQASSDDAH 201          
BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004614.1 (pep scaffold:Pmarinus_7.0:GL477874:5547:15173:-1 gene:ENSPMAG00000004198.1 transcript:ENSPMAT00000004614.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.071 bits (266), Expect = 1.655e-27
Identity = 72/219 (32.88%), Postives = 102/219 (46.58%), Query Frame = 2
Query:  395 FEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETV-LPFSTIYGR-PSGPPWSQDLVEWMTMTDLRISLMR---FTPEK-STPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRA 1033
            F++ Y+ L+   + P+S AIYK       W+P+QF+S  C R F +P+     +          LC      + ++D        + FST+ G   S  P S    EW+T TD+R+SL R   F  E    P  L+  YY                        +SDLAVGGRCKC+GHA+ C    +  + C C HNT G +CERC  ++  RPW +A
Sbjct:    1 FQITYVRLRFHTSRPESFAIYKRTSPASPWQPYQFYSGTCERTFGLPSRGFLRAG---DEERTALC-----SDEFSDISPLTGGNVAFSTLEGLFHSTGPLSSATQEWVTATDVRVSLRRLNTFGDEVFGDPKVLRSYYY-----------------------AVSDLAVGGRCKCHGHASECGRGSDGRLVCRCQHNTTGDDCERCLPSHNSRPWAQA 188          
BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008925.1 (pep scaffold:Pmarinus_7.0:GL476496:30277:70426:-1 gene:ENSPMAG00000008054.1 transcript:ENSPMAT00000008925.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 104.375 bits (259), Expect = 5.261e-24
Identity = 77/285 (27.02%), Postives = 128/285 (44.91%), Query Frame = 2
Query:  395 FEVYYIALQICGT-LPDSIAIYKSLDFGVSWKPWQFFS---QDCYRAFKM-PTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRC-LIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRG-------QHGGVCLECKHNTEGHACDECAAFHYR 1210
            F+V Y+ ++   +  P +  + +SLD G ++ PWQ++S    +C   + + PT      +       EV+C            G+  T L    I GRPS    S  L+++ +   +R+ L R          ++ L     +L    P  V+       ++ + D++VGG C C+GHA+ C   +D  +++C C HNT G+ C+ C   Y  R W+  T  N N C+ C C+  ++ C +   + +  R          GGVC+ C  NT G  C+ C    YR
Sbjct:    3 FQVAYVIVKAANSPRPGNWILERSLD-GATYHPWQYYSVSDSECLTRYGITPTVGNPVYR----RDDEVICTSYYVVLLMLARGKIHTSL----INGRPSADDPSPKLLDFTSARYIRLRLQR----------IRTLNADLMTLSHRDPREVDPIVTRRYYYSIKDISVGGMCICSGHASTCPWNEDTQKMECQCEHNTCGENCQHCCPGYNQRRWRPGTINNGNTCEKCNCHGKTEDCYYDAEVDRTNRSLSVHGRFSGGGVCVNCSANTAGTNCETCRDGFYR 268          
BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007784.1 (pep scaffold:Pmarinus_7.0:GL477336:382472:417638:1 gene:ENSPMAG00000007035.1 transcript:ENSPMAT00000007784.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.9745 bits (232), Expect = 1.247e-20
Identity = 76/283 (26.86%), Postives = 116/283 (40.99%), Query Frame = 2
Query:  365 VNITVSLKK-SFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMT---DLRISLMRF--TPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDND-EIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQH----GGVCLECKHNTEGHA 1180
            V +++ L+  S++V+Y+ +Q     P+ + I +    G  W  WQ F++DC   + M       S+  P          L+ P+  N        L F      P   P S+  V +  +T   +LR     F  TP         E+    E        +      P  +  +S++ V GRC+C+GHA RC          C    NTEG  CE C+  + D+PW+    +N N C+ C CY  +  C +   +     G H    GGVC +C  NT G A
Sbjct:  107 VAVSIELRGGSYQVFYVIVQFLSPQPEGVRIQRRPAAGSPWVDWQVFAKDCVSMYNM-------SKNGP----------LEKPDSVN-------CLQF------PREVPLSRGNVTFSVLTPEPNLRPGYNAFYATPALQAFVLAAEVRVLLEGRLLGVAGVAGGPLRP--YHAVSEVIVSGRCECHGHAERCDSSTTPYRCLCSAQSNTEGPNCELCRPLFRDKPWRAGDTRNQNACRPCLCYGRALSCRYEA-ILDPHPGLHWRGGGGVCQDCTQNTTGSA 356          
BLAST of Netrin 1 vs. Ensembl Nematostella
Match: EDO36836 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHI5])

HSP 1 Score: 237.269 bits (604), Expect = 3.188e-72
Identity = 135/400 (33.75%), Postives = 205/400 (51.25%), Query Frame = 2
Query:   74 QSSPCYLN-GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHR--SYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVE--LKAPERYNDYGQAETVLPFSTIYGRPSGPP--WSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEP--IVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            Q+  CY    R Q C P+F ++  N     + TCG        R +    +   R  C  CD ++   S+P  ++TD H   N TCW + P+Q    +  V + +S  K++++ Y++LQ CG  PDS+ IYKS+D+G SW+ +QF+S  C + +   T    N +I+P N    LC +  L  P     YG     + FST+ GRPS     +S  + EW+  TD+++                              N+++    P   +++ +S+  VGGRC CNGHA+ C+ D N    CDC HNT G +C  C+  + DRPW+ AT  +AN CK+C C  H+  C+FSM ++K + G+ GGVC++C+HNT G  C  C    Y+D  K +TH + C
Sbjct:    1 QAKDCYNEFNRAQLCQPAFHDLAYNKDVYVSHTCGEKS-----RRFCPPMSVRGRTACGFCDERNAKTSHPAKYLTDVHNENNVTCWQADPVQS---RENVTLILSFGKTYDITYVSLQFCGIRPDSMGIYKSMDYGKSWQAYQFYSSRCEKMYGRVT----NGEISPENEQVALCTDGHLLRPL----YGGR---IAFSTLEGRPSASKMDYSAVMQEWVMATDIKVEF----------------------------NMISRSARPRDSLYYAVSEFNVGGRCHCNGHASECVSDRNGRQVCDCKHNTVGVDCGACRPFFNDRPWRPATHHSANECKMCNCNLHARTCVFSMELFKLSGGRSGGVCVKCRHNTAGRYCHYCREGFYKDPNKHITHIKVC 353          
BLAST of Netrin 1 vs. Ensembl Nematostella
Match: EDO36523 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF3])

HSP 1 Score: 200.675 bits (509), Expect = 4.113e-56
Identity = 128/379 (33.77%), Postives = 187/379 (49.34%), Query Frame = 2
Query:   98 GRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRS--YPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPW--SQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRC----LIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYR 1210
            GR Q+C+P F N     +  + +TCG + P++ C         E R+ C +C++   +  +P   ITD     N+T W S  L ENP +  V +T+ L KS++V YI ++     P+S+AIYK       W P+Q+FS  C + + + T    N  + P N    LC +  +       G     + FST+  RP    +  S  L EW+T   +RI L R        +                PN++        ++ + DL++GGRCKCNGHA+ C    L D    ++C C H+TEG +CERCK  Y DRPW RA+ +NAN C  C C   ++ C+F   +Y+QT   HGG C  CK NT+G  C+ C    YR
Sbjct:   26 GRAQRCMPQFGNAAFGKRVISNNTCG-DPPKKFC---VQTGVLEVRKECEMCNSSDPALEHPALKITDIKDDTNRTWWQSETLLENPDK-PVTLTLDLGKSYDVSYIRIRFRSPRPESMAIYKKTTPSSKWIPYQYFSATCEKTYGVTT----NGIVDPRNQQVALCTDAFSTITPLTGGN----VAFSTLEDRPDAYNFDNSPALQEWVTAVAVRIHLRRMNTFGDEVF--------------GDPNVLRS-----YYYAIIDLSIGGRCKCNGHASECEETRLWDGQTRLQCKCQHDTEGVDCERCKPLYNDRPWARASSRNANECVRCNCNGLAESCVFDEALYRQT--GHGGRCQNCKQNTDGPNCERCKENFYR 370          
BLAST of Netrin 1 vs. Ensembl Nematostella
Match: EDO39502 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9X8])

HSP 1 Score: 157.532 bits (397), Expect = 2.118e-41
Identity = 110/402 (27.36%), Postives = 175/402 (43.53%), Query Frame = 2
Query:  107 QQCLPSFTNII---ENVKAETTSTCGTNGPEQICRNWYDKTTAEARQY--CSICDAKHRSYPPSHITDRHIPKNQTCWFSGPL-----QENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGR-----PSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEI-------KCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            + C P+  +++   EN K   +STCG  GPE+ C        +  + Y  C ICD++     P      H+PK     F G       Q   G+  V + + L+  F   ++ ++     P  + I +S D+G  W+ +++FS DC + F      E      P +I +V+C         N Y   E       I+       P    +S  +   + +T++RI+  +             L+   + L    P +         ++ + DL + G C C GHA +CL +            +C+C HNT G+ CERC+  Y D PW+ A   N N C+ C C  H+ KC F   +Y+ +    GGVC +C+HNT G  C+ C   HY+D +K  + P AC
Sbjct:   21 RSCYPATGDLLVGREN-KIYASSTCGLRGPEEYC------VVSNLQDYGDCHICDSRPYQTNPQF---SHVPKYMLSSFDGRKKDEWWQSENGRENVYLQLDLESEFHFTHLIMRFRTFRPAGMVIERSWDYGKKWQIYRYFSADCDKIFPGIPKGE------PKDIDDVICT--------NKYSTVEPSTNGEVIFRALKSQIPIKNAYSSKVQNLLKITNIRINFTK-------------LHTLGDDLLDPRPEIKRK-----YYYAVYDLVIRGSCSCYGHAEQCLPEPGQPTTPGMVYGRCNCTHNTTGKNCERCQDGYFDVPWRPADADNPNECRKCNCNGHAVKCRFDPAVYQASGNVSGGVCQDCEHNTVGRNCERCKPLHYQDPSKKFSDPDAC 380          

HSP 2 Score: 53.5286 bits (127), Expect = 1.644e-7
Identity = 39/119 (32.77%), Postives = 54/119 (45.38%), Query Frame = 2
Query:  896 CKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGV-CLECKHNTEGHACDECAAFHYRDITKPVTHPQACT 1249
            C+C GHA+ C  +    +  DC HNT G+ CE C   +    +  AT+   N CK CQC   S    FS   Y  T      V C +C+    G  C+ECA  +Y +   P    + C+
Sbjct:  850 CRCYGHASSC--NPKTGVCVDCQHNTVGKNCEACAVGF----YGIATKGTPNDCKRCQCPGGSSGNKFSESCYVDTSTTPPSVLCDKCQVGYTGRQCEECADGYYGNPLVPGGSCKPCS 962          
BLAST of Netrin 1 vs. Ensembl Nematostella
Match: EDO36500 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF5])

HSP 1 Score: 144.821 bits (364), Expect = 3.411e-37
Identity = 123/443 (27.77%), Postives = 202/443 (45.60%), Query Frame = 2
Query:   20 AILNLSVWIHSVKVIFESQSS----PCYL--NGRPQQCLP--SFTNIIENVKAETTSTCGTN--------GPEQICRNWYDKTTAEARQYCSICDA----KHRSYPPSHITDRHIP-----------KNQTCWFSGPLQENPGQN--EVNITVSLKKSFEVY-YIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            A L +   + S+ V   SQ++     CY    GR   C+P  SF ++  NV   T++TCGT         GPE                 C  CDA     +  +P +++ D  +            ++QT W +  L  +  +N  +VNIT+S  K +++  +I        P ++   KS DFG +W+    ++  C R + M    E  S   PAN  ++ C E  +       G    ++ F           ++ ++ +++++TD+R+ L     E      ++ LY   ++L +             +++ +S++ V GRC CNGHA  C        +C+C HNT G +CE C+  + +RPW RA + + N C+ C C NH+  C     +Y +T G   G+C  C+HNT+G  C  C A HYRD++KP+ H  AC
Sbjct:    6 ATLEILCVVGSLVVCLNSQNTCRFETCYERDTGRATPCMPFTSFMSLTRNVT--TSNTCGTTRAKYCELPGPEP----------------CYYCDANSSNSNEQHPVTNLVDNELVLPFYAQKYTWWQSQTWWETNQLGLSSIENPPKVNITLSFGKRYQLSGHIKATFYSKRPKAMCFDKSNDFGHTWETLLCYAWRCDRFYNM----EPQSNPDPANPFKLYCTEEYSGHEPRKLG----IVEFIASKRYEICDYFNPEVQDYLSVTDVRLRL-----EYPASDGMELLYQDEQTLNK-------------LYYAISNVEVTGRCSCNGHAMGCSGPIMSR-RCECEHNTMGTDCEMCEPLFNNRPWMRANQTHGNECQECNCNNHATSC-----VYNETLGY--GLCKGCQHNTQGDHCQNCTAKHYRDLSKPINHVNAC 396          
BLAST of Netrin 1 vs. Ensembl Nematostella
Match: EDO36501 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIF6])

HSP 1 Score: 141.354 bits (355), Expect = 6.503e-36
Identity = 114/423 (26.95%), Postives = 191/423 (45.15%), Query Frame = 2
Query:   26 LNLSVWIHSVKVIFESQSSPCYLNGR---PQQCLPS--FTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKH--RSYPPSHITDRHIPKNQTCWFSGP----LQENPGQN-EVNITVSLKKSFEVY-YIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYG-QAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNA-NVCKLCQCYNHSDKCMFSMGMYKQTRGQHG-GVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            L + +++ +V  +    +S C+ N +    Q C+P   F   +++    +TSTCG+  P + CR        +    C  C+A      +P  +I D+    + T W S       Q+NP  + +VN+++S  K++++  +I        P    + KS D G +W P Q++S +C + F M  T+   ++              K  E+Y+    Q    + F  +        +   + ++++ TDLR               L+  Y  T+ L  A   +    T    ++ +SDL V  RCKC+GHA  C         CDC HNT G +CERC   + ++ W  AT +   N C+ C+C++H+D C +S         Q G G C +C HNTEGH C+ C    YR+++  + HP+ C
Sbjct:    4 LGMVLFLLTVSKV----NSECFENEKYDDVQTCVPEPRFAAKMKHRAVSSTSTCGSP-PSEYCR-------VKPLNGCFKCNASSPTERHPIEYIADKSPGSDATFWQSETWWDWYQKNPRDDLKVNVSISFNKTYDITGHIMFTFESPRPSKAILEKSFDKGQTWDPLQYYSFNCRKDFGMENTDPTENRFGD--------FSAKCTEKYSSSSPQQNGKVTFDFLRRYNKASFFDTQVQQYLSATDLR---------------LRMEYPGTDGLEVAKDEV----TLKQYYYAVSDLEVIARCKCHGHARWCDFPHETGKNCDCLHNTTGDDCERCLPLFNNKTWMPATSETEPNPCERCECHSHADSCTYSQ--------QEGYGTCDDCYHNTEGHFCERCKDKFYRNMSLSLNHPEIC 379          
BLAST of Netrin 1 vs. Ensembl Medaka
Match: NTN1 (netrin-1 [Source:NCBI gene;Acc:101155405])

HSP 1 Score: 268.855 bits (686), Expect = 7.296e-84
Identity = 158/425 (37.18%), Postives = 226/425 (53.18%), Query Frame = 2
Query:   20 AILNLSVWIHSV-----KVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
             +L  S+W  S        +F +Q+SP   CY  +G P++C+P F N     + + +STCG   P + C     +   E  + C  CDA    + +PP+++TD + P N TCW S    + P QN V +T+SL K FEV Y++LQ C   P+S+ IYKS+D G +W P+QF+S  C + +  P      + IT  N  E +C +       + Y     ++ FST+ GRPS   +     L +W+T TD+++   R   F  E      L    Y                      + +SDL VGGRCKCNGHA+RC+ D +  + CDC HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C    YRD++KP++H +AC
Sbjct:    8 VLLAASLWCRSAFGGYGIGLFAAQTSPPDPCYDEHGNPRRCIPDFVNAAFGKEVKVSSTCGKT-PSRYCVVTSAEKGEERTRNCHSCDASDPKKYHPPAYLTDLNNPHNLTCWQSENFIQYP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMVIYKSMDNGKTWVPFQFYSTQCRKMYNKPN----RAVITKQNEQEAVCTD----SHTDMYPLTGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVVFSRLHTFGDENEDDSELARDSY---------------------FYAVSDLQVGGRCKCNGHASRCVKDRDGSLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKAC 400          
BLAST of Netrin 1 vs. Ensembl Medaka
Match: ntn2 (netrin-3 [Source:NCBI gene;Acc:101160359])

HSP 1 Score: 270.781 bits (691), Expect = 8.260e-84
Identity = 156/418 (37.32%), Postives = 226/418 (54.07%), Query Frame = 2
Query:   17 IAILNLSVWIHSVKVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            + +L  SV  HS    F  Q +P   CY   G  ++C+P F N     +   +S CG   P + C          + + C ICDA    R++P S++TD +   N TCW S  L  +P  + V +T+SL K FE+ Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C R +  P      + IT  N  E LC +       + Y  +  ++ FST+ GRPS   +     L +W+T+TD+R+   R  P+ S  + L      + +  +    +    T     + + D  VGGRCKCNGHA+RCL D   ++ CDC HNTEG EC+RCK  + DRPWQRA  + AN C  C C  H+ +C F+M +YK +  + GGVC+ C+HNT G  C  C    YRD+ +P+TH +AC
Sbjct:   11 LFLLVKSVSPHSPTSPFAGQQTPLDPCYDETGTARRCIPEFINAAFGKEVMVSSVCG-RPPSRSCSVVERGDERPSVRTCQICDAADPRRAHPASYLTDLNSAHNLTCWQSENLNTSP--HNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGKTWMPYQFYSSQCRRMYNKP----NKATITKQNEQEALCTD----GHTDLYPLSGGLIAFSTLDGRPSSKDFDNSPVLQDWVTVTDIRVVFGR--PQLSREFVLGA---GSNNGGRDDDPVAVTSTLSTYFYAVGDFQVGGRCKCNGHASRCLKDKEGKLVCDCKHNTEGPECDRCKPFHYDRPWQRANAREANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGRPITHRRAC 412          
BLAST of Netrin 1 vs. Ensembl Medaka
Match: ntn2 (netrin-3 [Source:NCBI gene;Acc:101160359])

HSP 1 Score: 270.781 bits (691), Expect = 8.260e-84
Identity = 156/418 (37.32%), Postives = 226/418 (54.07%), Query Frame = 2
Query:   17 IAILNLSVWIHSVKVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            + +L  SV  HS    F  Q +P   CY   G  ++C+P F N     +   +S CG   P + C          + + C ICDA    R++P S++TD +   N TCW S  L  +P  + V +T+SL K FE+ Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C R +  P      + IT  N  E LC +       + Y  +  ++ FST+ GRPS   +     L +W+T+TD+R+   R  P+ S  + L      + +  +    +    T     + + D  VGGRCKCNGHA+RCL D   ++ CDC HNTEG EC+RCK  + DRPWQRA  + AN C  C C  H+ +C F+M +YK +  + GGVC+ C+HNT G  C  C    YRD+ +P+TH +AC
Sbjct:   11 LFLLVKSVSPHSPTSPFAGQQTPLDPCYDETGTARRCIPEFINAAFGKEVMVSSVCG-RPPSRSCSVVERGDERPSVRTCQICDAADPRRAHPASYLTDLNSAHNLTCWQSENLNTSP--HNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGKTWMPYQFYSSQCRRMYNKP----NKATITKQNEQEALCTD----GHTDLYPLSGGLIAFSTLDGRPSSKDFDNSPVLQDWVTVTDIRVVFGR--PQLSREFVLGA---GSNNGGRDDDPVAVTSTLSTYFYAVGDFQVGGRCKCNGHASRCLKDKEGKLVCDCKHNTEGPECDRCKPFHYDRPWQRANAREANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGRPITHRRAC 412          
BLAST of Netrin 1 vs. Ensembl Medaka
Match: ntn2 (netrin-3 [Source:NCBI gene;Acc:101160359])

HSP 1 Score: 270.781 bits (691), Expect = 8.260e-84
Identity = 156/418 (37.32%), Postives = 226/418 (54.07%), Query Frame = 2
Query:   17 IAILNLSVWIHSVKVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            + +L  SV  HS    F  Q +P   CY   G  ++C+P F N     +   +S CG   P + C          + + C ICDA    R++P S++TD +   N TCW S  L  +P  + V +T+SL K FE+ Y++LQ C   P+S+AIYKS+D+G +W P+QF+S  C R +  P      + IT  N  E LC +       + Y  +  ++ FST+ GRPS   +     L +W+T+TD+R+   R  P+ S  + L      + +  +    +    T     + + D  VGGRCKCNGHA+RCL D   ++ CDC HNTEG EC+RCK  + DRPWQRA  + AN C  C C  H+ +C F+M +YK +  + GGVC+ C+HNT G  C  C    YRD+ +P+TH +AC
Sbjct:   11 LFLLVKSVSPHSPTSPFAGQQTPLDPCYDETGTARRCIPEFINAAFGKEVMVSSVCG-RPPSRSCSVVERGDERPSVRTCQICDAADPRRAHPASYLTDLNSAHNLTCWQSENLNTSP--HNVTLTLSLGKKFEITYVSLQFCSPRPESLAIYKSMDYGKTWMPYQFYSSQCRRMYNKP----NKATITKQNEQEALCTD----GHTDLYPLSGGLIAFSTLDGRPSSKDFDNSPVLQDWVTVTDIRVVFGR--PQLSREFVLGA---GSNNGGRDDDPVAVTSTLSTYFYAVGDFQVGGRCKCNGHASRCLKDKEGKLVCDCKHNTEGPECDRCKPFHYDRPWQRANAREANECLPCNCNLHARRCRFNMELYKLSGRKSGGVCMNCRHNTAGRHCHYCKEGFYRDMGRPITHRRAC 412          
BLAST of Netrin 1 vs. Ensembl Medaka
Match: NTN1 (netrin-1 [Source:NCBI gene;Acc:101155405])

HSP 1 Score: 268.47 bits (685), Expect = 3.237e-83
Identity = 158/425 (37.18%), Postives = 226/425 (53.18%), Query Frame = 2
Query:   20 AILNLSVWIHSV-----KVIFESQSSP---CY-LNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAK--HRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQD--LVEWMTMTDLRISLMR---FTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
             +L  S+W  S        +F +Q+SP   CY  +G P++C+P F N     + + +STCG   P + C     +   E  + C  CDA    + +PP+++TD + P N TCW S    + P QN V +T+SL K FEV Y++LQ C   P+S+ IYKS+D G +W P+QF+S  C + +  P      + IT  N  E +C +       + Y     ++ FST+ GRPS   +     L +W+T TD+++   R   F  E      L    Y                      + +SDL VGGRCKCNGHA+RC+ D +  + CDC HNT G EC+RCK  + DRPWQRAT + AN C  C C  H+ +C F+M +YK +  + GGVCL C+HNT G  C  C    YRD++KP++H +AC
Sbjct:    8 VLLAASLWCRSAFGGYGIGLFAAQTSPPDPCYDEHGNPRRCIPDFVNAAFGKEVKVSSTCGKT-PSRYCVVTSAEKGEERTRNCHSCDASDPKKYHPPAYLTDLNNPHNLTCWQSENFIQYP-QN-VTLTLSLGKKFEVTYVSLQFCSPRPESMVIYKSMDNGKTWVPFQFYSTQCRKMYNKPN----RAVITKQNEQEAVCTD----SHTDMYPLTGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVVFSRLHTFGDENEDDSELARDSY---------------------FYAVSDLQVGGRCKCNGHASRCVKDRDGSLVCDCKHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGFYRDLSKPISHRKAC 400          
BLAST of Netrin 1 vs. Planmine SMEST
Match: SMESG000050895.1 (SMESG000050895.1)

HSP 1 Score: 886.33 bits (2289), Expect = 0.000e+0
Identity = 426/456 (93.42%), Postives = 427/456 (93.64%), Query Frame = 2
Query:    2 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTNSWHR*VKAQSTR*YY*LRTVN*PIKIESGCKCHTIGSIK 1369
            IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACT+                             CKCHTIGSIK
Sbjct:    2 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTS-----------------------------CKCHTIGSIK 428          
BLAST of Netrin 1 vs. Planmine SMEST
Match: SMESG000050895.1 (SMESG000050895.1)

HSP 1 Score: 878.626 bits (2269), Expect = 0.000e+0
Identity = 416/417 (99.76%), Postives = 417/417 (100.00%), Query Frame = 2
Query:    2 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTN 1252
            IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACT+
Sbjct:    2 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTS 418          
BLAST of Netrin 1 vs. Planmine SMEST
Match: SMESG000050895.1 (SMESG000050895.1)

HSP 1 Score: 799.66 bits (2064), Expect = 0.000e+0
Identity = 388/456 (85.09%), Postives = 400/456 (87.72%), Query Frame = 2
Query:    2 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQACTNSWHR*VKAQSTR*YY*LRTVN*PIKIESGCKCHTIGSIK 1369
            IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCK C C  HS +C F+  +Y +    +GGVC+ C+H+T G+ C+ C    +R+ TKP  H  ACT                              CKCHTIGSIK
Sbjct:    2 IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKYCDCNLHSYRCYFNSQIYVRNNYTNGGVCINCRHHTTGNNCENCENGFFRNWTKPQEHRAACT-----------------------------SCKCHTIGSIK 428          
BLAST of Netrin 1 vs. Planmine SMEST
Match: SMESG000076695.1 (SMESG000076695.1)

HSP 1 Score: 332.028 bits (850), Expect = 6.272e-107
Identity = 169/422 (40.05%), Postives = 250/422 (59.24%), Query Frame = 2
Query:    2 IFIRTIAILNLSVWIH-SVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICD--AKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRFTPEKSTPYRLKELYYHTESLPQAPPNL----VNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
                +I +L  S +   ++ V++E++ + C  +G+   C P F NI +  K   TS+CG   P+ IC +W   ++   R  CSICD   K+  Y    +TD     N TCWFSGP+    G N VNI+++ KK+FEV+Y+ALQ C  LPDSI IYKS D G  W PWQ++S++C +AF +P T E   Q          C +L   ++  + GQAE++LPFS+  GR      +  L++W+T+TDLRI+L RF  + S+ +   + +       +   N+    VN K+   V++G+SDL+VGGRC+C GH+N+C+I+++  I CDC HNTEG +C++CK  + D  W+RA++ N   CK CQC  HS  C F   +Y +T  + GGVC +C+HNT G+ C  C   +YRD TKP++H  AC
Sbjct:    4 FLFNSILLLGFSFYFSVAISVLYENKQTTCEFHGKDYYCTPPFINIAQRAKITVTSSCGEILPDDICPHWKYYSSNHFRD-CSICDNDRKNSIYSIKSLTDPLNQFNHTCWFSGPVYNQHGLNHVNISIAFKKNFEVFYVALQFCSELPDSITIYKSHDNGKKWIPWQYYSKNCQKAFNLPPTQEFPIQEGLEYSLSPTCFDLNQKQKDGNLGQAESILPFSSTIGRK----MNDTLIKWITITDLRITLSRFDDQMSSYFDYGKYFLLKHRRGRDILNMSTFSVNDKSMSKVYYGVSDLSVGGRCQCYGHSNKCIINNDGNIVCDCKHNTEGADCDKCKEGFHDLQWERASKLNPFSCKRCQCNLHSQHCKFEKNVYMKTGQKSGGVCRKCQHNTAGNQCHFCDNGYYRDWTKPLSHDLAC 420          
BLAST of Netrin 1 vs. Planmine SMEST
Match: SMESG000069610.1 (SMESG000069610.1)

HSP 1 Score: 252.677 bits (644), Expect = 2.260e-77
Identity = 150/398 (37.69%), Postives = 204/398 (51.26%), Query Frame = 2
Query:   80 SPCYLNGRPQQCLPSFTNIIENVKAETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRHIPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGT-LPDSIAIYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHE----VLCVELKAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRF---TPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCKCNGHANRCLIDD-NDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNANVCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAFHYRDITKPVTHPQAC 1246
            SPCY +G   QC+P FTNI+EN+  +  + C                  + ++ C I     +S   + ITD H+  NQTCW S PLQ N     VNIT S  K FEVYYI+L  C + +P++IA YKS +FG++WKPW + + +C   F M  T   + Q     I        C  LK     N     E V+ F+T+            L++WM+ +D+RI+L +F    P+KS  +R                     +  P     +SD+++GGRCKCNGHAN C  +   ++I+C C HNTEGQ+CE+CK NYLD PW RAT  +   CK C+C  HS  C FS  +Y   +   GGVC  C+HNT G  C  C   +YRD TKP+ H   C
Sbjct:    7 SPCYAHGSAYQCMPPFTNIVENMIPKIETLC------------------KKKEVCPI-----KSPRDNLITDYHLTHNQTCWKSVPLQAN----HVNITFSFAKRFEVYYISLTPCESGIPNAIAFYKSNNFGITWKPWHYLATNCLSMFNMKETTIPSLQFNDFRIQRREQAARCFPLKLSLTDN-----EPVVAFNTVLEGAYENVGDSSLIDWMSASDIRITLFKFDNPKPKKSNIFRFA-------------------RNSPKKILSISDISIGGRCKCNGHANACNKNPITNKIECVCQHNTEGQDCEKCKKNYLDLPWARATVNSPAQCKKCECNLHSSNCYFSQDLYILRKQITGGVCTNCQHNTAGVRCHYCNDGYYRDWTKPLDHKFVC 353          
The following BLAST results are available for this feature:
BLAST of Netrin 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NTN18.699e-8438.50netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029][more]
NTN38.190e-6031.88netrin 3 [Source:HGNC Symbol;Acc:HGNC:8030][more]
LAMC17.823e-5232.81laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HG... [more]
LAMC31.378e-5033.33laminin subunit gamma 3 [Source:HGNC Symbol;Acc:HG... [more]
LAMA31.262e-4429.35laminin subunit alpha 3 [Source:HGNC Symbol;Acc:HG... [more]
back to top
BLAST of Netrin 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-65.306e-8136.71Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34... [more]
unc-65.306e-8136.71Netrin unc-6 [Source:UniProtKB/Swiss-Prot;Acc:P34... [more]
lam-28.938e-6133.50Laminin-like protein lam-2 [Source:UniProtKB/Swis... [more]
lam-34.130e-3729.17LAMinin related. See also lmb; Laminin alpha chain... [more]
lam-13.655e-3626.59LAMinin related. See also lmb [Source:UniProtKB/T... [more]
back to top
BLAST of Netrin 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NetA1.327e-8036.74gene:FBgn0015773 transcript:FBtr0308337[more]
NetA7.666e-8036.74gene:FBgn0015773 transcript:FBtr0073942[more]
NetA7.666e-8036.74gene:FBgn0015773 transcript:FBtr0346088[more]
LanB22.924e-5533.33gene:FBgn0267348 transcript:FBtr0345031[more]
LanB22.924e-5533.33gene:FBgn0267348 transcript:FBtr0076382[more]
back to top
BLAST of Netrin 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ntn28.816e-8638.23netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2][more]
ntn21.456e-8538.23netrin 2 [Source:ZFIN;Acc:ZDB-GENE-050310-2][more]
ntn1a1.987e-8537.68netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169][more]
ntn1a1.124e-8337.68netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169][more]
ntn1a1.124e-8337.68netrin 1a [Source:ZFIN;Acc:ZDB-GENE-990415-169][more]
back to top
BLAST of Netrin 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rps169.700e-8136.63ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-... [more]
rps162.806e-8035.63ribosomal protein S16 [Source:Xenbase;Acc:XB-GENE-... [more]
ntn17.479e-7738.07netrin 1 [Source:NCBI gene;Acc:779839][more]
utp45.340e-5132.24UTP4 small subunit processome component [Source:Xe... [more]
utp45.389e-5132.73UTP4 small subunit processome component [Source:Xe... [more]
back to top
BLAST of Netrin 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ntn12.371e-8338.25netrin 1 [Source:MGI Symbol;Acc:MGI:105088][more]
Ntn12.371e-8338.25netrin 1 [Source:MGI Symbol;Acc:MGI:105088][more]
Ntn33.619e-6433.33netrin 3 [Source:MGI Symbol;Acc:MGI:1341188][more]
Lamc38.130e-5432.02laminin gamma 3 [Source:MGI Symbol;Acc:MGI:1344394... [more]
Lamc39.467e-5432.02laminin gamma 3 [Source:MGI Symbol;Acc:MGI:1344394... [more]
back to top
BLAST of Netrin 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q90922|NET1_CHICK1.024e-8337.87Netrin-1 OS=Gallus gallus OX=9031 GN=NTN1 PE=1 SV=... [more]
sp|O95631|NET1_HUMAN4.178e-8338.50Netrin-1 OS=Homo sapiens OX=9606 GN=NTN1 PE=1 SV=2[more]
sp|Q2HXW4|NET1_PIG8.974e-8338.25Netrin-1 OS=Sus scrofa OX=9823 GN=NTN1 PE=2 SV=1[more]
sp|Q924Z9|NET1_RAT1.286e-8238.25Netrin-1 OS=Rattus norvegicus OX=10116 GN=Ntn1 PE=... [more]
sp|O09118|NET1_MOUSE1.658e-8238.25Netrin-1 OS=Mus musculus OX=10090 GN=Ntn1 PE=1 SV=... [more]
back to top
BLAST of Netrin 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
Q49BF80.000e+093.42Netrin 2 (Fragment) OS=Schmidtea mediterranea OX=7... [more]
E1CHK40.000e+074.34Netrin OS=Dugesia japonica OX=6161 GN=DjnetB PE=2 ... [more]
A0A5K4ERQ75.284e-12846.09Putative netrin OS=Schistosoma mansoni OX=6183 PE=... [more]
G4VQH86.122e-12748.96Putative netrin OS=Schistosoma mansoni OX=6183 GN=... [more]
A0A4Z2D9H41.182e-12543.60Netrin-A OS=Schistosoma japonicum OX=6182 GN=EWB00... [more]
back to top
BLAST of Netrin 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NTN16.673e-8739.15netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029][more]
NTN12.229e-8639.45netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029][more]
NTN11.357e-8539.45netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029][more]
ntn1b1.966e-8538.57netrin-1-like [Source:NCBI gene;Acc:111191060][more]
NTN11.027e-8439.45netrin 1 [Source:HGNC Symbol;Acc:HGNC:8029][more]
back to top
BLAST of Netrin 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000009682.11.060e-4433.33pep scaffold:Pmarinus_7.0:GL479835:738:11671:-1 ge... [more]
ENSPMAT00000004606.11.603e-2932.47pep scaffold:Pmarinus_7.0:GL477874:5526:15188:-1 g... [more]
ENSPMAT00000004614.11.655e-2732.88pep scaffold:Pmarinus_7.0:GL477874:5547:15173:-1 g... [more]
ENSPMAT00000008925.15.261e-2427.02pep scaffold:Pmarinus_7.0:GL476496:30277:70426:-1 ... [more]
ENSPMAT00000007784.11.247e-2026.86pep scaffold:Pmarinus_7.0:GL477336:382472:417638:1... [more]
back to top
BLAST of Netrin 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Netrin 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO368363.188e-7233.75Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO365234.113e-5633.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO395022.118e-4127.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO365003.411e-3727.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO365016.503e-3626.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Netrin 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NTN17.296e-8437.18netrin-1 [Source:NCBI gene;Acc:101155405][more]
ntn28.260e-8437.32netrin-3 [Source:NCBI gene;Acc:101160359][more]
ntn28.260e-8437.32netrin-3 [Source:NCBI gene;Acc:101160359][more]
ntn28.260e-8437.32netrin-3 [Source:NCBI gene;Acc:101160359][more]
NTN13.237e-8337.18netrin-1 [Source:NCBI gene;Acc:101155405][more]
back to top
BLAST of Netrin 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000050895.10.000e+093.42SMESG000050895.1[more]
SMESG000050895.10.000e+099.76SMESG000050895.1[more]
SMESG000050895.10.000e+085.09SMESG000050895.1[more]
SMESG000076695.16.272e-10740.05SMESG000076695.1[more]
SMESG000069610.12.260e-7737.69SMESG000069610.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022921 ID=SMED30022921|Name=Netrin 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1370bp
GATTTTTATAAGAACAATAGCAATTCTAAATTTATCAGTGTGGATTCATT
CTGTCAAGGTTATTTTTGAATCTCAGTCTTCACCATGCTATTTAAACGGG
AGGCCTCAACAGTGTTTGCCGTCTTTTACAAATATTATTGAAAACGTTAA
AGCAGAAACTACAAGTACGTGTGGGACCAATGGACCGGAACAGATTTGTC
GGAATTGGTATGACAAGACAACTGCAGAAGCCCGACAATATTGTAGTATA
TGCGACGCAAAACATCGTTCATATCCACCATCCCATATAACAGACCGACA
CATTCCAAAAAATCAAACATGTTGGTTTTCTGGACCGTTACAGGAAAATC
CTGGTCAAAATGAAGTCAATATTACTGTTTCGCTGAAGAAAAGCTTCGAA
GTTTATTACATTGCATTGCAAATCTGCGGAACACTTCCAGATTCAATAGC
AATTTACAAAAGCTTAGATTTTGGAGTTTCATGGAAACCTTGGCAGTTTT
TTTCACAAGATTGCTACAGGGCATTTAAAATGCCAACAACCAACGAACAG
AACTCTCAAATCACTCCTGCAAACATTCACGAAGTTCTTTGTGTTGAATT
AAAAGCCCCTGAACGATACAATGATTATGGACAAGCAGAAACTGTGTTAC
CGTTTAGTACCATTTATGGGCGACCATCTGGACCTCCATGGAGTCAAGAT
TTAGTTGAATGGATGACAATGACAGATTTGAGAATAAGTTTGATGAGATT
TACACCGGAAAAATCGACTCCATACAGATTGAAAGAATTGTATTATCATA
CCGAATCACTTCCCCAAGCACCACCGAATTTAGTCAACCATAAAACTGAG
CCGATTGTTCATTTTGGTTTGTCAGATCTTGCTGTTGGTGGACGCTGCAA
ATGCAATGGCCATGCTAATCGATGTTTGATTGATGATAACGATGAAATCA
AGTGTGACTGTCACCACAACACCGAAGGTCAAGAGTGTGAAAGATGCAAA
TCTAATTATCTTGATCGACCATGGCAAAGAGCAACCAGGCAAAATGCCAA
TGTCTGCAAATTATGCCAATGTTACAACCATTCTGATAAATGCATGTTCA
GCATGGGCATGTACAAACAAACTCGAGGACAACATGGAGGGGTTTGTTTG
GAATGCAAACACAATACAGAGGGTCACGCTTGTGATGAATGTGCTGCATT
TCATTATCGTGATATAACAAAACCAGTTACACATCCTCAAGCTTGTACAA
ATTCATGGCACAGGTAGGTGAAGGCGCAAAGCACCCGTTAATACTATTAA
TTGCGCACCGTGAACTAACCAATAAAAATCGAGTCAGGTTGCAAATGTCA
CACTATAGGATCTATTAAAC
back to top

protein sequence of SMED30022921-orf-1

>SMED30022921-orf-1 ID=SMED30022921-orf-1|Name=SMED30022921-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=422bp
IFIRTIAILNLSVWIHSVKVIFESQSSPCYLNGRPQQCLPSFTNIIENVK
AETTSTCGTNGPEQICRNWYDKTTAEARQYCSICDAKHRSYPPSHITDRH
IPKNQTCWFSGPLQENPGQNEVNITVSLKKSFEVYYIALQICGTLPDSIA
IYKSLDFGVSWKPWQFFSQDCYRAFKMPTTNEQNSQITPANIHEVLCVEL
KAPERYNDYGQAETVLPFSTIYGRPSGPPWSQDLVEWMTMTDLRISLMRF
TPEKSTPYRLKELYYHTESLPQAPPNLVNHKTEPIVHFGLSDLAVGGRCK
CNGHANRCLIDDNDEIKCDCHHNTEGQECERCKSNYLDRPWQRATRQNAN
VCKLCQCYNHSDKCMFSMGMYKQTRGQHGGVCLECKHNTEGHACDECAAF
HYRDITKPVTHPQACTNSWHR*
back to top
Aliases
The feature 'Netrin 1' has the following synonyms
Synonym
netrin-2
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000044cephalic ganglia
PLANA:0000097ventral nerve cord
PLANA:0000103central nervous system
PLANA:0000418head
PLANA:0000419prepharyngeal region
PLANA:0002056medial muscle cell
PLANA:0003104enteric muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR038684Laminin_N_sf
IPR008211Laminin_N
IPR002049Laminin_EGF
IPR008979Galactose-bd-like_sf
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002049Laminin EGF domainSMARTSM00180lamegf_3coord: 299..352
e-value: 7.9E-4
score: 28.7
coord: 355..415
e-value: 1.5E-5
score: 34.4
IPR002049Laminin EGF domainPFAMPF00053Laminin_EGFcoord: 299..344
e-value: 9.3E-7
score: 28.9
coord: 355..415
e-value: 7.7E-7
score: 29.2
IPR002049Laminin EGF domainPROSITEPS01248EGF_LAM_1coord: 318..352
IPR008211Laminin, N-terminalSMARTSM00136LamNT_2coord: 32..297
e-value: 2.6E-42
score: 156.5
IPR008211Laminin, N-terminalPFAMPF00055Laminin_Ncoord: 38..296
e-value: 1.4E-48
score: 165.5
IPR008211Laminin, N-terminalPROSITEPS51117LAMININ_NTERcoord: 34..298
score: 34.513
IPR038684Laminin, N-terminal domain superfamilyGENE3DG3DSA:2.60.120.1490coord: 15..320
e-value: 2.2E-70
score: 239.1
NoneNo IPR availableGENE3DG3DSA:2.10.25.10coord: 321..421
e-value: 2.2E-26
score: 94.0
NoneNo IPR availablePANTHERPTHR10574:SF292NETRIN-3coord: 20..416
NoneNo IPR availablePANTHERPTHR10574NETRIN/LAMININ-RELATEDcoord: 20..416
NoneNo IPR availableCDDcd00055EGF_Lamcoord: 298..343
e-value: 6.80678E-8
score: 46.5786
NoneNo IPR availableCDDcd00055EGF_Lamcoord: 355..404
e-value: 4.68273E-4
score: 35.793
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..17
score: 0.523
NoneNo IPR availableSUPERFAMILYSSF57196EGF/Laminincoord: 355..408
NoneNo IPR availableSUPERFAMILYSSF57196EGF/Laminincoord: 299..357