Synaptotagmin

Overview


Name	Synaptotagmin
Smed ID	SMED30022907
Length (bp)	1814

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Synaptotagmin (SMED30022907) t-SNE clustered cells

Violin plots show distribution of expression levels for Synaptotagmin (SMED30022907) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Synaptotagmin (SMED30022907) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Synaptotagmin (SMED30022907) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Expression Details

Synaptotagmin ( Dj-syt ) is expressed during Stage 3, Stage 4, Stage 5, Stage 6, Stage 7 and Stage 8 in the embryonic digestive system, neuron, cephalic ganglia, embryonic pharynx, nervous system, ventral nerve cord and pharynx nerve plexus

Click to see image symbols and abbreviations


Abbreviation or symbol	Definition
O	oral hemisphere
A	aboral hemisphere
D	dorsal
V	ventral
L	lateral
black arrowhead	embryonic pharynx
red arrowhead	definitive pharynx
black arrows	primitive gut
yellow arrows	primitive ectoderm cells
cyan arrows	brain
cyan arrowheads	nerve cords
blue arrowheads	eye progenitors (trail cells)
purple arrowheads	eyes
scale bar	100 µm

Anatomical Expression

PAGE et. al., 2020

SMED30022907

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 34

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30022907	h1SMcG0018919	SmedASXL_010967	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
Smed sexual biotype	SMED30022907	h1SMcG0018919	Contig48964	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30022907	h1SMcG0018919	Contig48964	newmark_ests	PMID:29674431 Fincher et al., 2018
pharynx	SMED30022907	h1SMcG0018919	dd_Smed_v4_4222_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30022907	h1SMcG0018919	dd_Smed_v4_4222_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30022907	h1SMcG0018919	dd_Smed_v4_4222_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30022907	h1SMcG0018919	dd_Smed_v4_4222_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30022907	h1SMcG0018919	dd_Smed_v4_4222_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30022907	h1SMcG0018919	dd_Smed_v4_4222_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30022907	h1SMcG0018919	dd_Smed_v4_4222_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30022907	h1SMcG0018919	dd_Smed_v4_4222_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30022907	h1SMcG0018919	dd_Smed_v6_4222_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
nervous system	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
nervous system	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
nervous system	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
nervous system	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
cephalic ganglia	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
cephalic ganglia	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
cephalic ganglia	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
peripheral nervous system	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
peripheral nervous system	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
peripheral nervous system	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
ventral nerve cord	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
ventral nerve cord	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
ventral nerve cord	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
pharynx nerve plexus	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
pharynx nerve plexus	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
pharynx nerve plexus	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
embryonic pharynx neuron	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
embryonic pharynx neuron	SMED30022907	h1SMcG0018919	SMED30022907	smed_20140614	PMID:28072387 Davies et al., 2017
head region	SMED30022907	h1SMcG0018919	OX_Smed_1.0.23351	ox_Smed_v2	PMID:24238224 Kao et al., 2013
neuron	SMED30022907	h1SMcG0018919	dd_Smed_v6_4222_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
cholinergic neuron	SMED30022907	h1SMcG0018919	dd_Smed_v6_4222_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
GABAergic neuron	SMED30022907	h1SMcG0018919	dd_Smed_v6_4222_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Synaptotagmin vs. Ensembl Human
Match: SYT1 (synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509])

HSP 1 Score: 414.075 bits (1063), Expect = 1.126e-139
Identity = 213/311 (68.49%), Postives = 256/311 (82.32%), Query Frame = 3

Query:  339 VVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
             ++MK  + LG + K++   D +      +  E  + KE+  LGKLQYSLDYDFQ  +L VG+IQA +LPA+DM GTSDPYVK++LLPDKKKKFETKVHRK LNPVFNE F FKVP++E+  KTL+  VYDFDRFSKHD IG+ KVP+  +D G V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV ++VTV+DYD+IG ++ IG++ +G N+TGAELRHWSDMLANPRRPIAQWHTLQ
Sbjct:  101 AINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQ 409

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Query:  339 VVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
             ++MK  + LG + K++   D +      +  E  + KE+  LGKLQYSLDYDFQ  +L VG+IQA +LPA+DM GTSDPYVK++LLPDKKKKFETKVHRK LNPVFNE F FKVP++E+  KTL+  VYDFDRFSKHD IG+ KVP+  +D G V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV ++VTV+DYD+IG ++ IG++ +G N+TGAELRHWSDMLANPRRPIAQWHTLQ
Sbjct:  101 AINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQ 409

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Query:  339 VVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
             ++MK  + LG + K++   D +      +  E  + KE+  LGKLQYSLDYDFQ  +L VG+IQA +LPA+DM GTSDPYVK++LLPDKKKKFETKVHRK LNPVFNE F FKVP++E+  KTL+  VYDFDRFSKHD IG+ KVP+  +D G V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV ++VTV+DYD+IG ++ IG++ +G N+TGAELRHWSDMLANPRRPIAQWHTLQ
Sbjct:  101 AINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQ 409

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BLAST of Synaptotagmin vs. Ensembl Human
Match: SYT1 (synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509])

HSP 1 Score: 412.149 bits (1058), Expect = 4.796e-139
Identity = 204/269 (75.84%), Postives = 237/269 (88.10%), Query Frame = 3

Query:  465 LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            LGKLQYSLDYDFQ  +L VG+IQA +LPA+DM GTSDPYVK++LLPDKKKKFETKVHRK LNPVFNE F FKVP++E+  KTL+  VYDFDRFSKHD IG+ KVP+  +D G V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV ++VTV+DYD+IG ++ IG++ +G N+TGAELRHWSDMLANPRRPIAQWHTLQ
Sbjct:  140 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQ 406

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BLAST of Synaptotagmin vs. Ensembl Human
Match: SYT2 (synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:11510])

HSP 1 Score: 402.134 bits (1032), Expect = 4.066e-135
Identity = 196/270 (72.59%), Postives = 236/270 (87.41%), Query Frame = 3

Query:  462 HLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            +LGKLQ+SLDYDFQ  +LTVGV+QA +LPA+DM GTSDPYVK++LLPDKKKK+ETKVHRK LNP FNETF FKVP+ E+  KTL+  +YDFDRFSKHD IG++KVP+  +DLG+ IEEW++L+  E   E+  +LGDIC SLRYVPT+GKLT+ ILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTT+KK TLNPY+NESFSFE+PFEQIQKV ++VTV+DYD++G +E IG+I +G NATG ELRHWSDMLANPRRPIAQWH+L+
Sbjct:  139 NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEK--EEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLK 406

HSP 2 Score: 84.7297 bits (208), Expect = 6.634e-17
Identity = 50/135 (37.04%), Postives = 84/135 (62.22%), Query Frame = 3

Query:  429 DNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKK--KFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKEL 827
            D +G +++E   LG +  SL Y    G+LTV +++A +L  MD+ G SDPYVK++L+ + K+  K +T V +K LNP FNE+F F++PF ++    ++  V D+D+  K++ IG+I V  G+   G  +  W ++
Sbjct:  259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFV--GSNATGTELRHWSDM 391

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BLAST of Synaptotagmin vs. Ensembl Celegans
Match: snt-1 (Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:P34693])

HSP 1 Score: 418.698 bits (1075), Expect = 1.113e-141
Identity = 226/317 (71.29%), Postives = 262/317 (82.65%), Query Frame = 3

Query:  339 VVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVH--LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPE 1283
            VVD K+ Q +          DLEEL   ME NE  + +E     LG++QY LDYDFQ+G+LTV VIQA DLP MDMSGTSDPYVKLYLLP+KKKK ETKVHRK LNPVFNETF+FKV FNE+ +KTL+F +YDFDRFSKHDQIGQ+ +PLG IDLG VIEEWK++  P +D E E  LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM  GKR+KKKKT+IKK TLNPYYNESFSFEVPFEQIQKV+L++TV+DYD++G+++ IGR +LGCN TGAELRHW DMLA+PRRPIAQWHTL  + E
Sbjct:  124 VVDGKNIQGMAQ--------DLEELGDAMEQNEKEQAEEKEEVKLGRIQYKLDYDFQQGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIFKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKIDLGAVIEEWKDIAPPPDDKEAEKSLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIVLMQGGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKVSLMITVMDYDKLGSNDAIGRCLLGCNGTGAELRHWMDMLASPRRPIAQWHTLGPVEE 432

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BLAST of Synaptotagmin vs. Ensembl Celegans
Match: snt-1 (Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:P34693])

HSP 1 Score: 389.808 bits (1000), Expect = 2.454e-130
Identity = 214/319 (67.08%), Postives = 257/319 (80.56%), Query Frame = 3

Query:  339 VVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVH--LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLM-LNGXXXXXXXXXXXXXXLNPYYNESFSFE-VPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPE 1283
            VVD K+ Q +          DLEEL   ME NE  + +E     LG++QY LDYDFQ+G+LTV VIQA DLP MDMSGTSDPYVKLYLLP+KKKK ETKVHRK LNPVFNETF+FKV FNE+ +KTL+F +YDFDRFSKHDQIGQ+ +PLG IDLG VIEEWK++  P +D E E  LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVKL +   + KR+KKKKT IK+ TLNPY+NESF F+ +P  +++KV+L++TV+DYD++G+++ IGR +LGCN TGAELRHW DMLA+PRRPIAQWHTL  + E
Sbjct:  124 VVDGKNIQGMAQ--------DLEELGDAMEQNEKEQAEEKEEVKLGRIQYKLDYDFQQGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIFKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKIDLGAVIEEWKDIAPPPDDKEAEKSLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKLEMFGEDRKRLKKKKTNIKRKTLNPYFNESFVFDKLPLHKMKKVSLMITVMDYDKLGSNDAIGRCLLGCNGTGAELRHWMDMLASPRRPIAQWHTLGPVEE 434

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BLAST of Synaptotagmin vs. Ensembl Celegans
Match: snt-3 (SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5])

HSP 1 Score: 350.903 bits (899), Expect = 1.716e-117
Identity = 173/268 (64.55%), Postives = 215/268 (80.22%), Query Frame = 3

Query:  465 LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTL 1268
            LG+LQY LDYDF K  LTV +IQA +LPAMD+ GTSDPYVKL+LLPDKKKK +TKV RK LNPVFNE+F FK+PFNE+  +TL+ NV+DFDRF KHDQIGQI +PLG +DL   +E    +ESP      ENRLG++C +LRYVP   KL++V++E KNLKKMDV GLSDPYVK+ LM+  KR++KKKTTIK  TLNPYYNESFSF+V  E++Q+V+L VTV DYDR+G++E IG++++G  ATG  L+ W+DMLA PRR +AQWHTL
Sbjct:   16 LGRLQYKLDYDFDKNSLTVVIIQAEELPAMDLGGTSDPYVKLFLLPDKKKKLQTKVQRKSLNPVFNESFTFKIPFNEIGGQTLVLNVFDFDRFGKHDQIGQISIPLGKVDLAATLERTDLIESPP-----ENRLGEVCLALRYVPNKNKLSVVVMECKNLKKMDVLGLSDPYVKIYLMMGTKRLEKKKTTIKMKTLNPYYNESFSFDVTSEKMQRVHLHVTVSDYDRVGSNERIGQVIIGTCATGVALKQWNDMLATPRRSVAQWHTL 278

HSP 2 Score: 73.1738 bits (178), Expect = 4.682e-14
Identity = 46/142 (32.39%), Postives = 81/142 (57.04%), Query Frame = 3

Query:  408 ELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKK--KFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKEL 827
            +L A +E  + ++   +  LG++  +L Y   K +L+V V++  +L  MD+ G SDPYVK+YL+   K+  K +T +  K LNP +NE+F F V   ++    L   V D+DR   +++IGQ+ +  G    G  +++W ++
Sbjct:  125 DLAATLERTDLIESPPENRLGEVCLALRYVPNKNKLSVVVMECKNLKKMDVLGLSDPYVKIYLMMGTKRLEKKKTTIKMKTLNPYYNESFSFDVTSEKMQRVHLHVTVSDYDRVGSNERIGQVII--GTCATGVALKQWNDM 264

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Query:  465 LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTL 1268
            LG+LQY LDYDF K  LTV +IQA +LPAMD+ GTSDPYVKL+LLPDKKKK +TKV RK LNPVFNE+F FK+PFNE+  +TL+ NV+DFDRF KHDQIGQI +PLG +DL   +E    +ESP      ENRLG++C +LRYVP   KL++V++E KNLKKMDV GLSDPYVK+ LM+  KR++KKKTTIK  TLNPYYNESFSF+V  E++Q+V+L VTV DYDR+G++E IG++++G  ATG  L+ W+DMLA PRR +AQWHTL
Sbjct:   16 LGRLQYKLDYDFDKNSLTVVIIQAEELPAMDLGGTSDPYVKLFLLPDKKKKLQTKVQRKSLNPVFNESFTFKIPFNEIGGQTLVLNVFDFDRFGKHDQIGQISIPLGKVDLAATLERTDLIESPP-----ENRLGEVCLALRYVPNKNKLSVVVMECKNLKKMDVLGLSDPYVKIYLMMGTKRLEKKKTTIKMKTLNPYYNESFSFDVTSEKMQRVHLHVTVSDYDRVGSNERIGQVIIGTCATGVALKQWNDMLATPRRSVAQWHTL 278

HSP 2 Score: 73.1738 bits (178), Expect = 4.682e-14
Identity = 46/142 (32.39%), Postives = 81/142 (57.04%), Query Frame = 3

Query:  408 ELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKK--KFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKEL 827
            +L A +E  + ++   +  LG++  +L Y   K +L+V V++  +L  MD+ G SDPYVK+YL+   K+  K +T +  K LNP +NE+F F V   ++    L   V D+DR   +++IGQ+ +  G    G  +++W ++
Sbjct:  125 DLAATLERTDLIESPPENRLGEVCLALRYVPNKNKLSVVVMECKNLKKMDVLGLSDPYVKIYLMMGTKRLEKKKTTIKMKTLNPYYNESFSFDVTSEKMQRVHLHVTVSDYDRVGSNERIGQVII--GTCATGVALKQWNDM 264

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BLAST of Synaptotagmin vs. Ensembl Celegans
Match: snt-2 (Synaptotagmin 2 [Source:UniProtKB/Swiss-Prot;Acc:K8FE10])

HSP 1 Score: 290.812 bits (743), Expect = 6.169e-93
Identity = 146/278 (52.52%), Postives = 200/278 (71.94%), Query Frame = 3

Query:  468 GKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGC------NATGAELRHWSDMLANPRRPIAQWHTLQEMPE 1283
            G + + ++YDF++ +L+V ++ A+DLPAMD +G SDPYVK+Y+LP++K+KFET++ R  LNP +NETF F +PFNE+ SKTL+  VYD+DR SK D++GQ+ VPL +ID G   +  + L+ PE D EKE RLGDICFS RY P +G +T+ I+EA+NLKKMDVGG SDPYVK+ L    K + KKKT+ K  TLNPYYNESF F++    I+KV+LIV+V DYD++  ++ IG + LG         T A    W++M+ + RRP+ QWHTLQE  E
Sbjct:   85 GNIHFRVEYDFEQSKLSVTIVSASDLPAMDRNGMSDPYVKVYVLPERKQKFETRIIRNTLNPTYNETFQFSIPFNELHSKTLMLVVYDYDRLSKDDKMGQLSVPLESIDFGITTDIERPLQKPEKDDEKECRLGDICFSTRYRPATGTVTLTIMEARNLKKMDVGGSSDPYVKIYLHHGRKLLSKKKTSRKYKTLNPYYNESFQFKIEPHMIEKVHLIVSVWDYDKMSKNDFIGEVTLGSKHLNLPQITHACSEQWAEMMTS-RRPVVQWHTLQERME 361

HSP 2 Score: 84.3445 bits (207), Expect = 2.816e-17
Identity = 45/133 (33.83%), Postives = 81/133 (60.90%), Query Frame = 3

Query:  447 EKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHR--KILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVI----EEWKEL 827
            ++++  LG + +S  Y    G +T+ +++A +L  MD+ G+SDPYVK+YL   +K   + K  R  K LNP +NE+F FK+  + +    LI +V+D+D+ SK+D IG++ +    ++L ++     E+W E+
Sbjct:  211 DEKECRLGDICFSTRYRPATGTVTLTIMEARNLKKMDVGGSSDPYVKIYLHHGRKLLSKKKTSRKYKTLNPYYNESFQFKIEPHMIEKVHLIVSVWDYDKMSKNDFIGEVTLGSKHLNLPQITHACSEQWAEM 343

HSP 3 Score: 71.2478 bits (173), Expect = 4.570e-13
Identity = 50/151 (33.11%), Postives = 80/151 (52.98%), Query Frame = 3

Query:  747 KHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKE--------NRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRI 1175
            KH  IG   VP+ +     V     +   P N+G            + G+I F + Y     KL++ I+ A +L  MD  G+SDPYVK+ ++   +R +K +T I + TLNP YNE+F F +PF ++    L++ V DYDR+   + +G++
Sbjct:   37 KHVDIGNGAVPILSSKPITVQPTNSDYYEPVNNGTLPLSSSGALIKQYGNIHFRVEYDFEQSKLSVTIVSASDLPAMDRNGMSDPYVKVYVL--PERKQKFETRIIRNTLNPTYNETFQFSIPFNELHSKTLMLVVYDYDRLSKDDKMGQL 185

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BLAST of Synaptotagmin vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077726)

HSP 1 Score: 456.062 bits (1172), Expect = 1.072e-155
Identity = 225/317 (70.98%), Postives = 270/317 (85.17%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFK-VPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLG++YKEK+QPD+EEL  N E+ +   ++ +  LG+L + L+YDF    L V VIQA +LPA+DM GTSDPYVK+YLLPDKKKKFETKVHRK L+PVFNETF FK +P+ +  +KTL+F ++DFDRFSKHDQIG++KVPL  IDL + IEEW++L S E +G +E +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+++M NGKR+KKKKT+IKK TLNPYYNESFSFEVPFEQIQK+ L+VTVVDYDRIGTSEPIGR +LGC  TG ELRHWSDMLA+PRRPIAQWHTL++  E +
Sbjct:  152 VDMKSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQE-KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKDPEETD 467

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BLAST of Synaptotagmin vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0343993)

HSP 1 Score: 454.136 bits (1167), Expect = 6.148e-155
Identity = 225/317 (70.98%), Postives = 268/317 (84.54%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFK-VPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLG++YKEK+QPD+EEL  N E+ +   ++ +  LG+L + L+YDF    L V VIQA +LPA+DM GTSDPYVK+YLLPDKKKKFETKVHRK L+PVFNETF FK +P+ +  +KTL+F ++DFDRFSKHDQIG++KVPL  IDL + IEEW++L S E  GE   +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+++M NGKR+KKKKT+IKK TLNPYYNESFSFEVPFEQIQK+ L+VTVVDYDRIGTSEPIGR +LGC  TG ELRHWSDMLA+PRRPIAQWHTL++  E +
Sbjct:  152 VDMKSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVE--GEGGQKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKDPEETD 466

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BLAST of Synaptotagmin vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0332218)

HSP 1 Score: 453.751 bits (1166), Expect = 7.713e-155
Identity = 224/317 (70.66%), Postives = 268/317 (84.54%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFK-VPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLG++YKEK+QPD+EEL  N E+ +   ++ +  LG+L + L+YDF    L V VIQA +LPA+DM GTSDPYVK+YLLPDKKKKFETKVHRK L+PVFNETF FK +P+ +  +KTL+F ++DFDRFSKHDQIG++KVPL  IDL + IEEW++L S E +G    +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+++M NGKR+KKKKT+IKK TLNPYYNESFSFEVPFEQIQK+ L+VTVVDYDRIGTSEPIGR +LGC  TG ELRHWSDMLA+PRRPIAQWHTL++  E +
Sbjct:  152 VDMKSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEG---GQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKDPEETD 465

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BLAST of Synaptotagmin vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077728)

HSP 1 Score: 447.973 bits (1151), Expect = 1.554e-152
Identity = 224/317 (70.66%), Postives = 268/317 (84.54%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFK-VPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLG++YKEK  PD+EEL  N E+ +   ++ +  LG+L + L+YDF    L V VIQA +LPA+DM GTSDPYVK+YLLPDKKKKFETKVHRK L+PVFNETF FK +P+ +  +KTL+F ++DFDRFSKHDQIG++KVPL  IDL + IEEW++L S E +G +E +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+++M NGKR+KKKKT+IKK TLNPYYNESFSFEVPFEQIQK+ L+VTVVDYDRIGTSEPIGR +LGC  TG ELRHWSDMLA+PRRPIAQWHTL++  E +
Sbjct:  152 VDMKSVQLLGSAYKEK--PDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQE-KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKDPEETD 465

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BLAST of Synaptotagmin vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0345331)

HSP 1 Score: 447.973 bits (1151), Expect = 1.554e-152
Identity = 224/317 (70.66%), Postives = 268/317 (84.54%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFK-VPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLG++YKEK  PD+EEL  N E+ +   ++ +  LG+L + L+YDF    L V VIQA +LPA+DM GTSDPYVK+YLLPDKKKKFETKVHRK L+PVFNETF FK +P+ +  +KTL+F ++DFDRFSKHDQIG++KVPL  IDL + IEEW++L S E +G +E +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+++M NGKR+KKKKT+IKK TLNPYYNESFSFEVPFEQIQK+ L+VTVVDYDRIGTSEPIGR +LGC  TG ELRHWSDMLA+PRRPIAQWHTL++  E +
Sbjct:  152 VDMKSVQLLGSAYKEK--PDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQE-KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKDPEETD 465

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BLAST of Synaptotagmin vs. Ensembl Zebrafish
Match: syt1a (synaptotagmin Ia [Source:ZFIN;Acc:ZDB-GENE-040718-165])

HSP 1 Score: 402.905 bits (1034), Expect = 1.280e-135
Identity = 197/269 (73.23%), Postives = 232/269 (86.25%), Query Frame = 3

Query:  465 LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            LGKLQYS+DY+F +  L VG+IQA +LPAMDM GTSDPYVK+YLLPDKKKKFETKVHRK LNPVFNE F FKVP+ E+  KTL+  VYDFDRFSKHD IG +KVP+  +D   V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+V+LEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV +++TV+DYD+IG ++ IG++ +G N+TG ELRHWSDMLANPRRPIAQWH L+
Sbjct:  139 LGKLQYSMDYNFTENTLIVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVITVLDYDKIGKNDAIGKVFVGLNSTGTELRHWSDMLANPRRPIAQWHVLK 405

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Query:  465 LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            LGKLQYS+DY+F +  L VG+IQA +LPAMDM GTSDPYVK+YLLPDKKKKFETKVHRK LNPVFNE F FKVP+ E+  KTL+  VYDFDRFSKHD IG +KVP+  +D   V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+V+LEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV +++TV+DYD+IG ++ IG++ +G N+TG ELRHWSDMLANPRRPIAQWH L+
Sbjct:  139 LGKLQYSMDYNFTENTLIVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVITVLDYDKIGKNDAIGKVFVGLNSTGTELRHWSDMLANPRRPIAQWHVLK 405

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BLAST of Synaptotagmin vs. Ensembl Zebrafish
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315])

HSP 1 Score: 376.326 bits (965), Expect = 4.286e-125
Identity = 184/269 (68.40%), Postives = 229/269 (85.13%), Query Frame = 3

Query:  465 LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            LGKLQ+SLDYDF   +LTVG++QA DL +MD  GTSDPYVK+++LPDKKKK++TKVH+K LNPVFNETF FK+PF E+  KTL+ +VYDFDRFSKHD IG++K+P+  +DL + IE+W++L+S E   E+  +LGDIC SLRYVPT+GKLTI ILEAKNLKKMDVGGLSDPYVK+ L+ NGKR+KKKKTT+KK TLNPYYNESFSFE+P +Q+QK+  ++TV+DYD+IG ++ IG+I +G  A G ELRHWSDMLANPRRPIAQWH L+
Sbjct:  148 LGKLQFSLDYDFSASQLTVGILQAADLLSMDSGGTSDPYVKVFILPDKKKKYDTKVHKKTLNPVFNETFHFKIPFTEMGGKTLVMSVYDFDRFSKHDVIGEVKIPMNTLDLAQPIEQWRDLDSAEK--EEPEKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPQDQMQKIQAVITVLDYDKIGKNDAIGKIWVGSKAQGTELRHWSDMLANPRRPIAQWHPLK 414

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Query:  465 LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            LGKLQ+SLDYDF   +LTVG++QA DL +MD  GTSDPYVK+++LPDKKKK++TKVH+K LNPVFNETF FK+PF E+  KTL+ +VYDFDRFSKHD IG++K+P+  +DL + IE+W++L+S E   E+  +LGDIC SLRYVPT+GKLTI ILEAKNLKKMDVGGLSDPYVK+ L+ NGKR+KKKKTT+KK TLNPYYNESFSFE+P +Q+QK+  ++TV+DYD+IG ++ IG+I +G  A G ELRHWSDMLANPRRPIAQWH L+
Sbjct:  148 LGKLQFSLDYDFSASQLTVGILQAADLLSMDSGGTSDPYVKVFILPDKKKKYDTKVHKKTLNPVFNETFHFKIPFTEMGGKTLVMSVYDFDRFSKHDVIGEVKIPMNTLDLAQPIEQWRDLDSAEK--EEPEKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKIHLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPQDQMQKIQAVITVLDYDKIGKNDAIGKIWVGSKAQGTELRHWSDMLANPRRPIAQWHPLK 414

[Close]

BLAST of Synaptotagmin vs. Ensembl Zebrafish
Match: syt5a (synaptotagmin Va [Source:ZFIN;Acc:ZDB-GENE-040718-110])

HSP 1 Score: 372.859 bits (956), Expect = 6.134e-124
Identity = 180/266 (67.67%), Postives = 228/266 (85.71%), Query Frame = 3

Query:  474 LQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            L+Y+LDY+F + +L VG++QA DLPAMD+ GTSDPYVK+Y+LPDKKKKFETKV RK L PVFNETF+FK+PFN++A +TL+  V+DFDRF KHD IG+IK+P+ +IDLG+ I E+K+L   E   E++ +LGDIC SLRYVPTSGKLT+ I+EAKNLKKMDVGGLSDP+VK+ L  NGKR+KKKKTT+K+ TLNPY+NESFSFE+PF QIQKV +++TV DYD++G+++PIG+  +G  A+G  LRHWSDMLANPRRP+AQWHTLQ
Sbjct:  133 LEYTLDYNFTENQLIVGILQAQDLPAMDIGGTSDPYVKVYMLPDKKKKFETKVQRKNLCPVFNETFIFKIPFNDLAGQTLVLQVFDFDRFGKHDVIGEIKIPMNSIDLGQPIHEYKDLVGGEK--EEQEKLGDICISLRYVPTSGKLTVCIMEAKNLKKMDVGGLSDPFVKIVLQHNGKRIKKKKTTVKQNTLNPYFNESFSFEIPFAQIQKVQVLITVYDYDKLGSNDPIGKCWIGFGASGVGLRHWSDMLANPRRPVAQWHTLQ 396

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BLAST of Synaptotagmin vs. Ensembl Xenopus
Match: SYT5 (synaptotagmin 5 [Source:NCBI gene;Acc:100493612])

HSP 1 Score: 441.425 bits (1134), Expect = 2.000e-150
Identity = 220/311 (70.74%), Postives = 267/311 (85.85%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVK-EKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            ++MK  + LG SY +K+QPD+E+LD ++ D+  VK EK    LGKLQYSLDYDFQ G+L VG+IQA DLPA+D+ GTSDPYVK+YLLPDKKKK+ETKVHRK LNP FNE+F FKVP+ E+  KTL+ +VYDFDRFSKHD IG+++V +  +DL  VIEEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+++LEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV +++TV+DYD++G +E IG+I +GCNATG ELRHWSDMLANPRRPIAQWHTLQ
Sbjct:  101 INMKEVKELGKSYIDKVQPDVEDLDPSLLDD--VKDEKPQEKLGKLQYSLDYDFQTGQLVVGIIQAADLPALDIGGTSDPYVKVYLLPDKKKKYETKVHRKTLNPTFNESFTFKVPYAELGGKTLVMSVYDFDRFSKHDAIGEVRVHMNTVDLAHVIEEWQDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVLTVLDYDKLGKNEAIGKIFVGCNATGTELRHWSDMLANPRRPIAQWHTLQ 407

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BLAST of Synaptotagmin vs. Ensembl Xenopus
Match: SYT5 (synaptotagmin 5 [Source:NCBI gene;Acc:100493612])

HSP 1 Score: 441.039 bits (1133), Expect = 2.005e-150
Identity = 220/311 (70.74%), Postives = 267/311 (85.85%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVK-EKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            ++MK  + LG SY +K+QPD+E+LD ++ D+  VK EK    LGKLQYSLDYDFQ G+L VG+IQA DLPA+D+ GTSDPYVK+YLLPDKKKK+ETKVHRK LNP FNE+F FKVP+ E+  KTL+ +VYDFDRFSKHD IG+++V +  +DL  VIEEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+++LEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV +++TV+DYD++G +E IG+I +GCNATG ELRHWSDMLANPRRPIAQWHTLQ
Sbjct:   96 INMKEVKELGKSYIDKVQPDVEDLDPSLLDD--VKDEKPQEKLGKLQYSLDYDFQTGQLVVGIIQAADLPALDIGGTSDPYVKVYLLPDKKKKYETKVHRKTLNPTFNESFTFKVPYAELGGKTLVMSVYDFDRFSKHDAIGEVRVHMNTVDLAHVIEEWQDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVLTVLDYDKLGKNEAIGKIFVGCNATGTELRHWSDMLANPRRPIAQWHTLQ 402

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BLAST of Synaptotagmin vs. Ensembl Xenopus
Match: e2f4 (E2F transcription factor 4 [Source:Xenbase;Acc:XB-GENE-482721])

HSP 1 Score: 414.461 bits (1064), Expect = 7.564e-140
Identity = 212/312 (67.95%), Postives = 259/312 (83.01%), Query Frame = 3

Query:  339 VVDMKSAQLLGNSYKEK-IQPDLEELDANMEDNEGVKEKEDVH-LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTL 1268
             ++MK  + LG + K++ ++ D ++ +  + D E  ++ ++V  LGKLQYSLDYDFQ  +L VG+IQA +LPA+DM GTSDPYVKL+L+PDKKKKFETKVHRK LNPVFNE F FKVP+ E+  KTL+  VYDFDRFSKHD IG +KVP+  +D G V EEW++L S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV ++VTV+DYD+IG ++ IG++ +G N+TGAELRHWSDMLANPRRPIAQWHTL
Sbjct:  102 AINMKDVKDLGKTMKDQALKDDDDDAETGLTDGEDKEQPKEVEKLGKLQYSLDYDFQNNQLMVGIIQAAELPALDMGGTSDPYVKLFLMPDKKKKFETKVHRKTLNPVFNEQFTFKVPYAELGGKTLVLTVYDFDRFSKHDVIGDVKVPMNTVDFGHVTEEWRDLVSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 411

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BLAST of Synaptotagmin vs. Ensembl Xenopus
Match: luzp2 (leucine zipper protein 2 [Source:Xenbase;Acc:XB-GENE-940667])

HSP 1 Score: 394.43 bits (1012), Expect = 4.693e-132
Identity = 189/265 (71.32%), Postives = 231/265 (87.17%), Query Frame = 3

Query:  477 QYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            Q+SLDYDFQ  ++ VG+IQAT+LPA+DM GTSDPYVK++ LPDKKKK ETKVHRK LNP+FNETF FK+P+ E+  KTL  ++YDFDRFSKHD IG++KVP+  +DLG+ IEEW++L+S E   E+  +LGDIC SLRYVPT+GKLT+ ILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTT+KK TLNPY+NESFSFE+PFEQIQKV +++TV+DYD++G +E IG+I +GCNA+G ELRHWSDMLANPRRPIAQWH L+
Sbjct:  150 QFSLDYDFQNNQMQVGIIQATELPALDMGGTSDPYVKVFFLPDKKKKHETKVHRKTLNPIFNETFTFKIPYQELGGKTLCMSIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQSAEK--EEPEKLGDICISLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVITVLDYDKLGKNEAIGKIFVGCNASGTELRHWSDMLANPRRPIAQWHPLK 412

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BLAST of Synaptotagmin vs. Ensembl Xenopus
Match: syt8 (synaptotagmin 8 [Source:NCBI gene;Acc:100037878])

HSP 1 Score: 332.798 bits (852), Expect = 1.941e-108
Identity = 174/305 (57.05%), Postives = 225/305 (73.77%), Query Frame = 3

Query:  369 GNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPE 1283
            GN     +QP       N++  E V+ +     G++QYSL+Y+FQ  ELTVGV QA  L AMD+ GTSDPY  +Y+  D +KKFETKV+RK LNPVFNE+FVFKV   EV   T +  ++DF+RF KHD IG++ +PLG ++L  VIE+WK+L  P    E E+ LGDICFSLRYVP+SGKLTI+ILEAKNLK+MD  G SDPYVK+ L LN K+ K+KKT +KK TL PY+NESF+F+V  EQ++ ++LI++V D+D++G +E IG++ LGC A+G  LRHWSDMLA+PRRPIAQWH LQE  E
Sbjct:   83 GNLTTHLVQPGA----GNLQKGEKVEYR-----GRVQYSLEYNFQTEELTVGVKQAAALKAMDLGGTSDPYAIVYVTNDTRKKFETKVNRKTLNPVFNESFVFKVTQEEVPRTTAVVQIFDFNRFLKHDVIGEMVIPLGEVNLQHVIEDWKDL-GPAGKTEHEH-LGDICFSLRYVPSSGKLTIIILEAKNLKRMDSDGFSDPYVKVHLALNRKKWKRKKTAVKKSTLKPYFNESFTFDVSLEQMKNLDLIISVWDHDKVGKNEQIGKLFLGCRASGNALRHWSDMLAHPRRPIAQWHKLQEADE 376

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BLAST of Synaptotagmin vs. Ensembl Mouse
Match: Syt1 (synaptotagmin I [Source:MGI Symbol;Acc:MGI:99667])

HSP 1 Score: 414.846 bits (1065), Expect = 4.302e-140
Identity = 213/310 (68.71%), Postives = 256/310 (82.58%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            ++MK  + LG + K++   D +      +  E  + KE+  LGKLQYSLDYDFQ  +L VG+IQA +LPA+DM GTSDPYVK++LLPDKKKKFETKVHRK LNPVFNE F FKVP++E+  KTL+  VYDFDRFSKHD IG+ KVP+  +D G V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV ++VTV+DYD+IG ++ IG++ +G N+TGAELRHWSDMLANPRRPIAQWHTLQ
Sbjct:  101 INMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQ 408

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Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            ++MK  + LG + K++   D +      +  E  + KE+  LGKLQYSLDYDFQ  +L VG+IQA +LPA+DM GTSDPYVK++LLPDKKKKFETKVHRK LNPVFNE F FKVP++E+  KTL+  VYDFDRFSKHD IG+ KVP+  +D G V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV ++VTV+DYD+IG ++ IG++ +G N+TGAELRHWSDMLANPRRPIAQWHTLQ
Sbjct:  101 INMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQ 408

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BLAST of Synaptotagmin vs. Ensembl Mouse
Match: Syt2 (synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666])

HSP 1 Score: 402.519 bits (1033), Expect = 2.304e-135
Identity = 196/270 (72.59%), Postives = 236/270 (87.41%), Query Frame = 3

Query:  462 HLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            +LGKLQ+SLDYDFQ  +LTVGV+QA +LPA+DM GTSDPYVK++LLPDKKKK+ETKVHRK LNP FNETF FKVP+ E+  KTL+  +YDFDRFSKHD IG++KVP+  +DLG+ IEEW++L+  E   E+  +LGDIC SLRYVPT+GKLT+ ILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTT+KK TLNPY+NESFSFE+PFEQIQKV ++VTV+DYD++G +E IG+I +G NATG ELRHWSDMLANPRRPIAQWH+L+
Sbjct:  142 NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEK--EEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLK 409

HSP 2 Score: 85.1149 bits (209), Expect = 4.098e-17
Identity = 50/135 (37.04%), Postives = 84/135 (62.22%), Query Frame = 3

Query:  429 DNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKK--KFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKEL 827
            D +G +++E   LG +  SL Y    G+LTV +++A +L  MD+ G SDPYVK++L+ + K+  K +T V +K LNP FNE+F F++PF ++    ++  V D+D+  K++ IG+I V  G+   G  +  W ++
Sbjct:  262 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFV--GSNATGTELRHWSDM 394

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Query:  462 HLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            +LGKLQ+SLDYDFQ  +LTVGV+QA +LPA+DM GTSDPYVK++LLPDKKKK+ETKVHRK LNP FNETF FKVP+ E+  KTL+  +YDFDRFSKHD IG++KVP+  +DLG+ IEEW++L+  E   E+  +LGDIC SLRYVPT+GKLT+ ILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTT+KK TLNPY+NESFSFE+PFEQIQKV ++VTV+DYD++G +E IG+I +G NATG ELRHWSDMLANPRRPIAQWH+L+
Sbjct:  142 NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEK--EEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLK 409

HSP 2 Score: 85.1149 bits (209), Expect = 4.098e-17
Identity = 50/135 (37.04%), Postives = 84/135 (62.22%), Query Frame = 3

Query:  429 DNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKK--KFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKEL 827
            D +G +++E   LG +  SL Y    G+LTV +++A +L  MD+ G SDPYVK++L+ + K+  K +T V +K LNP FNE+F F++PF ++    ++  V D+D+  K++ IG+I V  G+   G  +  W ++
Sbjct:  262 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFV--GSNATGTELRHWSDM 394

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BLAST of Synaptotagmin vs. Ensembl Mouse
Match: Syt5 (synaptotagmin V [Source:MGI Symbol;Acc:MGI:1926368])

HSP 1 Score: 368.622 bits (945), Expect = 1.154e-122
Identity = 186/311 (59.81%), Postives = 250/311 (80.39%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELE-SPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            V ++  + LG SY +K+QP++EELD +     G +  +   LG+LQYSLDYDFQ G+L VG++QA  L A+D+ G+SDPYV +YLLPDK+++ ETKVHR+ LNP F ETF FKVP+ E+  + L+  VYDFDRFS++D IG+++VP+ +++LGR ++ W+EL+ +P+ + EK   LGDICFSLRYVPT+GKLT+++LEAKNLKKMDVGGLSDPYVK+ L+  GK+V+KKKTTIKK TLNPYYNE+FSFEVP +Q+QKV + +TV+DYD++G +E IGR+ +G    GA LRHW+DMLANPRRPIAQWH+L+
Sbjct:   69 VHLQEVKELGRSYIDKVQPEIEELDRS-PSMPGQQVSDKHQLGRLQYSLDYDFQTGQLLVGILQAQGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVAPKEEQEK---LGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAVGGAGLRHWADMLANPRRPIAQWHSLR 375

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BLAST of Synaptotagmin vs. UniProt/SwissProt
Match: sp|P41823|SY65_APLCA (Synaptotagmin-1 OS=Aplysia californica OX=6500 GN=SYT1 PE=1 SV=2)

HSP 1 Score: 511.916 bits (1317), Expect = 2.452e-177
Identity = 254/318 (79.87%), Postives = 286/318 (89.94%), Query Frame = 3

Query:  339 VVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKE-KEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
             VD+KS QLLGNSYKEK+QPDL+EL  NMEDNE  +  K +V LGKLQ+SLDYDFQKGEL+V VIQA DLP MDMSGTSDPYVK+YLLPDKKKK+ETKVHRK LNPVFNE+F FKVP+ EV SK L F VYDFDRFSKHDQIGQ++VPL +IDLGRV+E+WK+L+SP+ + EKEN+LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK++L+   KR+KKKKTTIKK TLNPY+NESF FEVPFEQIQKV LI+TVVDYDRIGTSEPIGR VLGCN++G ELRHWSDMLANPRRPIAQWHTLQE+PE N
Sbjct:  111 AVDLKSVQLLGNSYKEKVQPDLDELPVNMEDNEDAESTKSEVKLGKLQFSLDYDFQKGELSVNVIQAADLPGMDMSGTSDPYVKVYLLPDKKKKYETKVHRKTLNPVFNESFTFKVPYAEVGSKILTFAVYDFDRFSKHDQIGQVQVPLNSIDLGRVVEDWKDLQSPDTESEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIALLQGTKRLKKKKTTIKKNTLNPYFNESFGFEVPFEQIQKVTLIITVVDYDRIGTSEPIGRCVLGCNSSGTELRHWSDMLANPRRPIAQWHTLQEVPEKN 428

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BLAST of Synaptotagmin vs. UniProt/SwissProt
Match: sp|P21521|SY65_DROME (Synaptotagmin 1 OS=Drosophila melanogaster OX=7227 GN=Syt1 PE=1 SV=3)

HSP 1 Score: 456.062 bits (1172), Expect = 1.075e-154
Identity = 225/317 (70.98%), Postives = 270/317 (85.17%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFK-VPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLG++YKEK+QPD+EEL  N E+ +   ++ +  LG+L + L+YDF    L V VIQA +LPA+DM GTSDPYVK+YLLPDKKKKFETKVHRK L+PVFNETF FK +P+ +  +KTL+F ++DFDRFSKHDQIG++KVPL  IDL + IEEW++L S E +G +E +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+++M NGKR+KKKKT+IKK TLNPYYNESFSFEVPFEQIQK+ L+VTVVDYDRIGTSEPIGR +LGC  TG ELRHWSDMLA+PRRPIAQWHTL++  E +
Sbjct:  152 VDMKSVQLLGSAYKEKVQPDMEELTENAEEGDEEDKQSEQKLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQE-KLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTLKDPEETD 467

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BLAST of Synaptotagmin vs. UniProt/SwissProt
Match: sp|P34693|SYT1_CAEEL (Synaptotagmin-1 OS=Caenorhabditis elegans OX=6239 GN=snt-1 PE=2 SV=1)

HSP 1 Score: 418.698 bits (1075), Expect = 1.416e-140
Identity = 226/317 (71.29%), Postives = 262/317 (82.65%), Query Frame = 3

Query:  339 VVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVH--LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPE 1283
            VVD K+ Q +          DLEEL   ME NE  + +E     LG++QY LDYDFQ+G+LTV VIQA DLP MDMSGTSDPYVKLYLLP+KKKK ETKVHRK LNPVFNETF+FKV FNE+ +KTL+F +YDFDRFSKHDQIGQ+ +PLG IDLG VIEEWK++  P +D E E  LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM  GKR+KKKKT+IKK TLNPYYNESFSFEVPFEQIQKV+L++TV+DYD++G+++ IGR +LGCN TGAELRHW DMLA+PRRPIAQWHTL  + E
Sbjct:  124 VVDGKNIQGMAQ--------DLEELGDAMEQNEKEQAEEKEEVKLGRIQYKLDYDFQQGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKKKVETKVHRKTLNPVFNETFIFKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKIDLGAVIEEWKDIAPPPDDKEAEKSLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIVLMQGGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKVSLMITVMDYDKLGSNDAIGRCLLGCNGTGAELRHWMDMLASPRRPIAQWHTLGPVEE 432

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BLAST of Synaptotagmin vs. UniProt/SwissProt
Match: sp|P46096|SYT1_MOUSE (Synaptotagmin-1 OS=Mus musculus OX=10090 GN=Syt1 PE=1 SV=1)

HSP 1 Score: 414.846 bits (1065), Expect = 3.010e-139
Identity = 213/310 (68.71%), Postives = 256/310 (82.58%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            ++MK  + LG + K++   D +      +  E  + KE+  LGKLQYSLDYDFQ  +L VG+IQA +LPA+DM GTSDPYVK++LLPDKKKKFETKVHRK LNPVFNE F FKVP++E+  KTL+  VYDFDRFSKHD IG+ KVP+  +D G V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV ++VTV+DYD+IG ++ IG++ +G N+TGAELRHWSDMLANPRRPIAQWHTLQ
Sbjct:  101 INMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQ 408

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BLAST of Synaptotagmin vs. UniProt/SwissProt
Match: sp|P21707|SYT1_RAT (Synaptotagmin-1 OS=Rattus norvegicus OX=10116 GN=Syt1 PE=1 SV=3)

HSP 1 Score: 414.461 bits (1064), Expect = 3.391e-139
Identity = 213/310 (68.71%), Postives = 256/310 (82.58%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            ++MK  + LG + K++   D +      +  E  + KE+  LGKLQYSLDYDFQ  +L VG+IQA +LPA+DM GTSDPYVK++LLPDKKKKFETKVHRK LNPVFNE F FKVP++E+  KTL+  VYDFDRFSKHD IG+ KVP+  +D G V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV ++VTV+DYD+IG ++ IG++ +G N+TGAELRHWSDMLANPRRPIAQWHTLQ
Sbjct:  101 INMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQ 408

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BLAST of Synaptotagmin vs. TrEMBL
Match: Q9U8R6 (Djsyt protein OS=Dugesia japonica OX=6161 GN=Djsyt PE=2 SV=1)

HSP 1 Score: 662.144 bits (1707), Expect = 0.000e+0
Identity = 379/395 (95.95%), Postives = 389/395 (98.48%), Query Frame = 3

Query:  105 MKNSTHGSDHSASKASMKTNVEKFWHDLGKKLHMDPKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            MKN THG+DH+ SK+ MK NV+KFW+DLGKKLHMDP+ALIGVT+GLGILFLLFLYCLCKKCVFKRRKKKE  KKGAKGVVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKL+LLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTL+FNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESP+NDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN
Sbjct:    1 MKNVTHGTDHTVSKSDMKNNVQKFWNDLGKKLHMDPRALIGVTVGLGILFLLFLYCLCKKCVFKRRKKKEAGKKGAKGVVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLFLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLVFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPDNDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 395

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BLAST of Synaptotagmin vs. TrEMBL
Match: A0A267E333 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031935g3 PE=4 SV=1)

HSP 1 Score: 542.347 bits (1396), Expect = 0.000e+0
Identity = 269/316 (85.13%), Postives = 294/316 (93.04%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLGN YKEK+QPD+EEL   MEDNEG +EKE   LGKLQYSLDYDFQKGEL+VGVIQA+DLPAMDM GTSDPYVK+Y++P+KKKKFETKVHRK LNPVFNETF+FKVP+ +V SKTL+F VYDFDRFSKHDQIG IK+PLGAIDL R+IEEWK+++ PE++ +K NRLGDICFSLRYVPT+GKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV+LIVTVVDYDRIGTSEPIGRIVLGC ATGAELRHWSDMLANPRRPIAQWHTLQEMPE +
Sbjct:  116 VDMKSVQLLGNEYKEKVQPDMEELVETMEDNEGAQEKEVEKLGKLQYSLDYDFQKGELSVGVIQASDLPAMDMGGTSDPYVKVYIMPEKKKKFETKVHRKTLNPVFNETFIFKVPYADVPSKTLVFAVYDFDRFSKHDQIGLIKLPLGAIDLARLIEEWKDIDPPESEDDKSNRLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFSFEVPFEQIQKVSLIVTVVDYDRIGTSEPIGRIVLGCTATGAELRHWSDMLANPRRPIAQWHTLQEMPEKS 431

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BLAST of Synaptotagmin vs. TrEMBL
Match: A0A267GS86 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031935g1 PE=4 SV=1)

HSP 1 Score: 541.576 bits (1394), Expect = 0.000e+0
Identity = 269/316 (85.13%), Postives = 294/316 (93.04%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLGN YKEK+QPD+EEL   MEDNEG +EKE   LGKLQYSLDYDFQKGEL+VGVIQA+DLPAMDM GTSDPYVK+Y++P+KKKKFETKVHRK LNPVFNETF+FKVP+ +V SKTL+F VYDFDRFSKHDQIG IK+PLGAIDL R+IEEWK+++ PE++ +K NRLGDICFSLRYVPT+GKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV+LIVTVVDYDRIGTSEPIGRIVLGC ATGAELRHWSDMLANPRRPIAQWHTLQEMPE +
Sbjct:  116 VDMKSVQLLGNEYKEKVQPDMEELVETMEDNEGAQEKEVEKLGKLQYSLDYDFQKGELSVGVIQASDLPAMDMGGTSDPYVKVYIMPEKKKKFETKVHRKTLNPVFNETFIFKVPYADVPSKTLVFAVYDFDRFSKHDQIGLIKLPLGAIDLARLIEEWKDIDPPESEDDKSNRLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFSFEVPFEQIQKVSLIVTVVDYDRIGTSEPIGRIVLGCTATGAELRHWSDMLANPRRPIAQWHTLQEMPEKS 431

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BLAST of Synaptotagmin vs. TrEMBL
Match: A0A267E6V1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031935g2 PE=4 SV=1)

HSP 1 Score: 541.191 bits (1393), Expect = 0.000e+0
Identity = 270/316 (85.44%), Postives = 294/316 (93.04%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLGN YKEK+QPD+EEL   MEDNEG +EKE   LGKLQYSLDYDFQKGEL+VGVIQA+DLPAMDM GTSDPYVK+Y+LP+KKKKFETKVHRK LNPVFNETF+FKVP+ +V SKTL+F VYDFDRFSKHDQIG IK+PLGAIDL R+IEEWK+++ PE++ +K NRLGDICFSLRYVPT+GKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV+LIVTVVDYDRIGTSEPIGRIVLGC ATGAELRHWSDMLANPRRPIAQWHTLQEMPE +
Sbjct:  116 VDMKSVQLLGNEYKEKVQPDMEELVETMEDNEGNQEKEVEKLGKLQYSLDYDFQKGELSVGVIQASDLPAMDMGGTSDPYVKVYILPEKKKKFETKVHRKTLNPVFNETFIFKVPYADVPSKTLVFAVYDFDRFSKHDQIGLIKLPLGAIDLARLIEEWKDIDPPESEDDKSNRLGDICFSLRYVPTAGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFSFEVPFEQIQKVSLIVTVVDYDRIGTSEPIGRIVLGCTATGAELRHWSDMLANPRRPIAQWHTLQEMPEKS 431

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BLAST of Synaptotagmin vs. TrEMBL
Match: R7U5Y9 (Synaptotagmin 1 variant OS=Capitella teleta OX=283909 GN=Syt1 PE=4 SV=1)

HSP 1 Score: 528.094 bits (1359), Expect = 0.000e+0
Identity = 261/316 (82.59%), Postives = 290/316 (91.77%), Query Frame = 3

Query:  339 VVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKE-KEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPE 1283
             VD+ S ++LGNSYKEK+QPDLEEL+ NMEDNE  +  K +V LGKLQ+SLDYDFQKGEL VGVIQ  DLP MDMSGTSDPYVK+YLLP+KKKK ETKVHRK LNPVFNETF FKVP+ E+ SKTL+F VYDFDRFSKHDQIGQ+KVPL ++DLGRV+EEW++L SPE+D EKEN+LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPYVKLSLMLNGKR+KKKKTTIKK TLNPYYNESF+FEVPFEQIQKV +I+TVVDYDRIGTSEPIGR+VLGCN+TG ELRHWSDMLANPRRPIAQWHTLQEMPE
Sbjct:  121 AVDLGSVKILGNSYKEKVQPDLEELEVNMEDNEDAESTKSEVKLGKLQFSLDYDFQKGELAVGVIQGADLPGMDMSGTSDPYVKVYLLPEKKKKHETKVHRKTLNPVFNETFNFKVPYAEMGSKTLVFAVYDFDRFSKHDQIGQVKVPLNSVDLGRVVEEWRDLTSPESDSEKENKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRIKKKKTTIKKCTLNPYYNESFTFEVPFEQIQKVTMIITVVDYDRIGTSEPIGRVVLGCNSTGTELRHWSDMLANPRRPIAQWHTLQEMPE 436

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BLAST of Synaptotagmin vs. Ensembl Cavefish
Match: syt1a (synaptotagmin 1 [Source:NCBI gene;Acc:103044539])

HSP 1 Score: 406.757 bits (1044), Expect = 4.113e-137
Identity = 203/292 (69.52%), Postives = 242/292 (82.88%), Query Frame = 3

Query:  399 DLEELDANMEDNEGVKE-KEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            D +E++  + +NE   E KE   LGKLQYSLDY+F +  L VG+IQA +LPAMDM GTSDPYVK+YLLPDKKKKFETKVHRK LNP FNE F FKVP+ E+  KTL+  VYDFDRFSKHD IG +KVP+  +D   V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPY K+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV +++TV+DYD+IG ++ IG++ +G N++G ELRHWSDMLANPRRPIAQWH L+
Sbjct:  116 DEDEVETGLTENEKEAEPKEQEKLGKLQYSLDYNFTENTLIVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPTFNEQFTFKVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYAKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQIVITVLDYDKIGKNDAIGKVFVGLNSSGTELRHWSDMLANPRRPIAQWHVLK 405

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BLAST of Synaptotagmin vs. Ensembl Cavefish
Match: syt1a (synaptotagmin 1 [Source:NCBI gene;Acc:103044539])

HSP 1 Score: 406.371 bits (1043), Expect = 4.375e-137
Identity = 203/292 (69.52%), Postives = 242/292 (82.88%), Query Frame = 3

Query:  399 DLEELDANMEDNEGVKE-KEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            D +E++  + +NE   E KE   LGKLQYSLDY+F +  L VG+IQA +LPAMDM GTSDPYVK+YLLPDKKKKFETKVHRK LNP FNE F FKVP+ E+  KTL+  VYDFDRFSKHD IG +KVP+  +D   V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+VILEAKNLKKMDVGGLSDPY K+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV +++TV+DYD+IG ++ IG++ +G N++G ELRHWSDMLANPRRPIAQWH L+
Sbjct:  113 DEDEVETGLTENEKEAEPKEQEKLGKLQYSLDYNFTENTLIVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPTFNEQFTFKVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYAKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQIVITVLDYDKIGKNDAIGKVFVGLNSSGTELRHWSDMLANPRRPIAQWHVLK 402

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BLAST of Synaptotagmin vs. Ensembl Cavefish
Match: syt1b (synaptotagmin Ib [Source:ZFIN;Acc:ZDB-GENE-060503-166])

HSP 1 Score: 389.037 bits (998), Expect = 3.101e-130
Identity = 193/274 (70.44%), Postives = 230/274 (83.94%), Query Frame = 3

Query:  450 KEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            KE+  LGKLQ+SLDY F  G L VG+IQA DL AMDMSGTSDPYVKLYLLPDKKKKFETKVHRK LNP FNE F FKVP++E+  KTL+  VYDFDRFSKHD IG ++V +  +D  +V EEW+ L+  E   E++ +LGDIC SLRYVPT+GKLT+V+LEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK+TLNPYYNESFSFEVP EQIQKV ++VTV+DYD+IG ++ IG++ +G +++G E RHW+DMLANPRRPIAQWH L+
Sbjct:  133 KEEQKLGKLQFSLDYHFTDGSLIVGIIQAEDLAAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKTLNPTFNEHFTFKVPYSELGGKTLVMTVYDFDRFSKHDAIGDVRVQMNKVDFSQVTEEWRVLQKAEK--EEQEKLGDICLSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKHTLNPYYNESFSFEVPSEQIQKVQVVVTVLDYDKIGKNDAIGKVFMGLHSSGTEQRHWADMLANPRRPIAQWHALK 404

[Close]

BLAST of Synaptotagmin vs. Ensembl Cavefish
Match: syt1b (synaptotagmin Ib [Source:ZFIN;Acc:ZDB-GENE-060503-166])

HSP 1 Score: 389.037 bits (998), Expect = 3.317e-130
Identity = 193/274 (70.44%), Postives = 230/274 (83.94%), Query Frame = 3

Query:  450 KEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            KE+  LGKLQ+SLDY F  G L VG+IQA DL AMDMSGTSDPYVKLYLLPDKKKKFETKVHRK LNP FNE F FKVP++E+  KTL+  VYDFDRFSKHD IG ++V +  +D  +V EEW+ L+  E   E++ +LGDIC SLRYVPT+GKLT+V+LEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK+TLNPYYNESFSFEVP EQIQKV ++VTV+DYD+IG ++ IG++ +G +++G E RHW+DMLANPRRPIAQWH L+
Sbjct:  136 KEEQKLGKLQFSLDYHFTDGSLIVGIIQAEDLAAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKTLNPTFNEHFTFKVPYSELGGKTLVMTVYDFDRFSKHDAIGDVRVQMNKVDFSQVTEEWRVLQKAEK--EEQEKLGDICLSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKHTLNPYYNESFSFEVPSEQIQKVQVVVTVLDYDKIGKNDAIGKVFMGLHSSGTEQRHWADMLANPRRPIAQWHALK 407

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BLAST of Synaptotagmin vs. Ensembl Cavefish
Match: syt5b (synaptotagmin-1-like [Source:NCBI gene;Acc:103029888])

HSP 1 Score: 380.178 bits (975), Expect = 2.267e-126
Identity = 186/274 (67.88%), Postives = 233/274 (85.04%), Query Frame = 3

Query:  462 HLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPE 1283
            HLGKL++SLDY+F + +L VG++QA DL AMD+ GTSDPYVK++LLPDKKKKFETKV RK L PVFNETF+FK+P+ E+  K L+  VYDFDRF KHD IGQIK+P+  +DLG+ + +W++LES E   E++ +LGD+C SLRYVPT+GKLT+ I+EAKNLKKMDVGGLSDP+VK+ L  NGKR+KKKKTT+KK TLNPY+NESFSFE+PFEQIQKV L++TV DYD++G+++PIG+I +G  ATG  LRHWSDMLANPRRP+AQWHTL  +PE
Sbjct:  162 HLGKLEFSLDYNFTEAQLIVGILQAQDLAAMDIGGTSDPYVKVFLLPDKKKKFETKVQRKNLCPVFNETFIFKIPYAELGGKILVLLVYDFDRFGKHDVIGQIKIPMNCVDLGQPLHQWRDLESAEK--EEQEKLGDVCISLRYVPTAGKLTVNIMEAKNLKKMDVGGLSDPFVKIVLQHNGKRLKKKKTTVKKNTLNPYFNESFSFEIPFEQIQKVQLLITVYDYDKLGSNDPIGKIFIGYGATGVGLRHWSDMLANPRRPVAQWHTL--LPE 431

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BLAST of Synaptotagmin vs. Ensembl Sea Lamprey
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315])

HSP 1 Score: 203.371 bits (516), Expect = 3.859e-62
Identity = 99/157 (63.06%), Postives = 126/157 (80.25%), Query Frame = 3

Query:  399 DLEELDANMEDNE-GVKEKEDVH-------LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPEND 845
            D++++D + ED E G+ E ++         LGKLQ+S+DYDFQ  +LTVGVIQA +LPA+DM GTSDPYVKL+L+PDKKKK+ETKVHRK LNPVFNE+FVFKVP++E+  KTL+  VYDFDRFSKHD IG++KVP+  IDLG VIEEW++L S E +
Sbjct:   50 DVKDMDNDKEDLETGLTEGDEKEEEKEEEKLGKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPDKKKKYETKVHRKTLNPVFNESFVFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEVKVPMNTIDLGHVIEEWRDLVSAEKE 206

HSP 2 Score: 77.0258 bits (188), Expect = 2.025e-16
Identity = 46/125 (36.80%), Postives = 76/125 (60.80%), Query Frame = 3

Query:  864 LGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNAT--GAELRHWSDMLA 1232
            LG + FS+ Y   + +LT+ +++A  L  +D+GG SDPYVKL LM +  + KK +T + + TLNP +NESF F+VP+ ++    L++ V D+DR    + IG + +  N    G  +  W D+++
Sbjct:   80 LGKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPD--KKKKYETKVHRKTLNPVFNESFVFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEVKVPMNTIDLGHVIEEWRDLVS 202

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BLAST of Synaptotagmin vs. Ensembl Sea Lamprey
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315])

HSP 1 Score: 204.142 bits (518), Expect = 4.034e-62
Identity = 103/169 (60.95%), Postives = 134/169 (79.29%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANM-EDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPEND 845
            ++MK  + + N  K +   + E+L+  + E +E  +EKE+  LGKLQ+S+DYDFQ  +LTVGVIQA +LPA+DM GTSDPYVKL+L+PDKKKK+ETKVHRK LNPVFNE+FVFKVP++E+  KTL+  VYDFDRFSKHD IG++KVP+  IDLG VIEEW++L S E +
Sbjct:   56 INMKDVKDMDNDKKNQAHSE-EDLETGLTEGDEKEEEKEEEKLGKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPDKKKKYETKVHRKTLNPVFNESFVFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEVKVPMNTIDLGHVIEEWRDLVSAEKE 223

HSP 2 Score: 79.337 bits (194), Expect = 5.767e-17
Identity = 47/137 (34.31%), Postives = 81/137 (59.12%), Query Frame = 3

Query:  864 LGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNAT--GAELRHWSDMLANPRRPIAQWHTL 1268
            LG + FS+ Y   + +LT+ +++A  L  +D+GG SDPYVKL LM +  + KK +T + + TLNP +NESF F+VP+ ++    L++ V D+DR    + IG + +  N    G  +  W D+++  +  +++   L
Sbjct:   97 LGKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPD--KKKKYETKVHRKTLNPVFNESFVFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEVKVPMNTIDLGHVIEEWRDLVSAEKEEVSRARRL 231

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BLAST of Synaptotagmin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006908.1 (pep scaffold:Pmarinus_7.0:GL476344:649897:653668:1 gene:ENSPMAG00000006246.1 transcript:ENSPMAT00000006908.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 187.578 bits (475), Expect = 4.862e-57
Identity = 91/139 (65.47%), Postives = 116/139 (83.45%), Query Frame = 3

Query:  852 KENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTL 1268
            +++RLGDICFSLRY+P++GKLTIVILEA NLK MDV G SDPYVK+ +M  G R+KKKKTT+KK  LNPY+NE+FSF++PFE I+K+ L+ +V+DYD +  ++ IG++ +GC A GA  RHWSDMLANPRRPI QWHTL
Sbjct:    6 QQDRLGDICFSLRYIPSTGKLTIVILEATNLKVMDVSGASDPYVKIQVMEGGIRLKKKKTTVKKKALNPYFNEAFSFDIPFENIEKIQLVFSVMDYDSLSRNDAIGKVYVGCGAAGAGHRHWSDMLANPRRPITQWHTL 144

HSP 2 Score: 88.1965 bits (217), Expect = 6.587e-21
Identity = 50/123 (40.65%), Postives = 76/123 (61.79%), Query Frame = 3

Query:  465 LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPD--KKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKEL 827
            LG + +SL Y    G+LT+ +++AT+L  MD+SG SDPYVK+ ++    + KK +T V +K LNP FNE F F +PF  +    L+F+V D+D  S++D IG++ V  GA   G     W ++
Sbjct:   10 LGDICFSLRYIPSTGKLTIVILEATNLKVMDVSGASDPYVKIQVMEGGIRLKKKKTTVKKKALNPYFNEAFSFDIPFENIEKIQLVFSVMDYDSLSRNDAIGKVYVGCGAAGAGH--RHWSDM 130

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BLAST of Synaptotagmin vs. Ensembl Sea Lamprey
Match: SYT5 (synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513])

HSP 1 Score: 185.267 bits (469), Expect = 2.441e-55
Identity = 84/160 (52.50%), Postives = 115/160 (71.88%), Query Frame = 3

Query:  378 YKEKIQPDLEELDANMEDNEGVKEKEDVH----LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPEND 845
            +K K+QPDLE++D            ED++    LG+LQ+SLDY+ +  + TVG++QATDL AMD+ G SDPYV++YLLP KKKKFET VHRK LNP+F E F F VPF E+  + L+  VYDFDRFS+HD IG++++PL ++DL   +EEW++L+  E D
Sbjct:   54 FKNKVQPDLEDIDPGF--------IEDIYKENTLGRLQFSLDYNLKTSQFTVGILQATDLAAMDIGGMSDPYVRVYLLPHKKKKFETSVHRKTLNPIFEEKFTFTVPFEELVERVLVMVVYDFDRFSRHDIIGELRIPLSSVDLSHSVEEWRDLQKTEKD 205

HSP 2 Score: 83.9593 bits (206), Expect = 7.549e-19
Identity = 51/130 (39.23%), Postives = 79/130 (60.77%), Query Frame = 3

Query:  843 DGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIG--RIVLGCNATGAELRHWSDM 1226
            D  KEN LG + FSL Y   + + T+ IL+A +L  MD+GG+SDPYV++ L+ +  + KK +T++ + TLNP + E F+F VPFE++ +  L++ V D+DR    + IG  RI L        +  W D+
Sbjct:   72 DIYKENTLGRLQFSLDYNLKTSQFTVGILQATDLAAMDIGGMSDPYVRVYLLPH--KKKKFETSVHRKTLNPIFEEKFTFTVPFEELVERVLVMVVYDFDRFSRHDIIGELRIPLSSVDLSHSVEEWRDL 199

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BLAST of Synaptotagmin vs. Ensembl Sea Lamprey
Match: SYT6 (synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638])

HSP 1 Score: 147.902 bits (372), Expect = 5.048e-41
Identity = 69/123 (56.10%), Postives = 91/123 (73.98%), Query Frame = 3

Query:  468 GKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVP--LGAIDLGRVIEEWKELE 830
            GKL ++L YD++  +L V V +A +LPA D SGTSDPYVK+YLLPD+K+K++TKVHRK LNPVF ETF F VP+ E+ ++ L F+VYDFDRFS+HD IGQ+ V       DL R    W+++E
Sbjct:  114 GKLNFALHYDYEMEQLLVRVCRAAELPAKDFSGTSDPYVKIYLLPDRKRKYQTKVHRKTLNPVFEETFQFFVPYAELPARRLHFSVYDFDRFSRHDTIGQVVVDNLFEESDLSRETSLWRDIE 236

HSP 2 Score: 59.3066 bits (142), Expect = 3.611e-10
Identity = 43/142 (30.28%), Postives = 71/142 (50.00%), Query Frame = 3

Query:  789 IDLGRVIEEWKELESPEND-----------GEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVL 1181
            +D+GR+  E  +  S E D            +     G + F+L Y     +L + +  A  L   D  G SDPYVK+ L+ +  R +K +T + + TLNP + E+F F VP+ ++    L  +V D+DR    + IG++V+
Sbjct:   77 LDIGRIKPELYKQRSVEGDDADGGCGTTAANDGRTLAGKLNFALHYDYEMEQLLVRVCRAAELPAKDFSGTSDPYVKIYLLPD--RKRKYQTKVHRKTLNPVFEETFQFFVPYAELPARRLHFSVYDFDRFSRHDTIGQVVV 216

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BLAST of Synaptotagmin vs. Ensembl Yeast
Match: TCB3 (Cortical ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to the plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact [Source:SGD;Acc:S000004537])

HSP 1 Score: 62.7734 bits (151), Expect = 1.284e-10
Identity = 32/100 (32.00%), Postives = 60/100 (60.00%), Query Frame = 3

Query:  507 GELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRV 806
            G L + +I    L + D +G SDP+V +++  + KK F++ + +K L+PV+NE    K+P    +   +IFNV D+DR   +D +GQ  + + ++++G+ 
Sbjct: 1134 GYLNIKLISGHGLKSADRNGYSDPFVHIFV--NDKKVFKSNIKKKTLDPVWNEDA--KIPILSRSKNQVIFNVLDWDRAGDNDDLGQASLDVSSLEVGKT 1229

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BLAST of Synaptotagmin vs. Ensembl Yeast
Match: TCB1 (Lipid-binding ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane and regulate PI4P levels by controlling access of Sac1p phosphatase to its substrate PI4P in PM; contains 3 calcium and lipid binding domains; non-tagged protein also localizes to mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact; TCB1 has a paralog, TCB2, that arose from the whole genome duplication [Source:SGD;Acc:S000005612])

HSP 1 Score: 61.6178 bits (148), Expect = 2.782e-10
Identity = 41/128 (32.03%), Postives = 67/128 (52.34%), Query Frame = 3

Query:  507 GELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLR 890
            G+LT+    A +L A D++G SDPY+K Y+  ++   ++TKV +K LNP +N+    ++  N   +  L   V D+D  S  D IG  ++PL  + +    E    +E  EN G+    L  + FS +
Sbjct:  992 GDLTIMSRSAENLIASDLNGYSDPYLKYYINNEEDCAYKTKVVKKTLNPKWNDEGTIQI--NNRLNDVLRIKVMDWDSTSADDTIGTAEIPLNKVKVEGTTELDVPVEGLENAGQDGGML-HLAFSFK 1116

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BLAST of Synaptotagmin vs. Ensembl Yeast
Match: TCB2 (ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; contains 3 calcium and lipid binding domains; mRNA is targeted to bud; TCB2 has a paralog, TCB1, that arose from the whole genome duplication [Source:SGD;Acc:S000005031])

HSP 1 Score: 52.373 bits (124), Expect = 2.075e-7
Identity = 34/97 (35.05%), Postives = 53/97 (54.64%), Query Frame = 3

Query:  507 GELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKK-FETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAID 794
            G+L +    A +L  ++ +G SDPYV+ +L        F+T V +K LNP +NE+   +V  N V +  L  NV D++  + +  IG+  VPL  ID
Sbjct:  983 GDLKITAKSAENLIGVNKNGYSDPYVEFFLNEKSTSPFFKTAVQKKTLNPTWNESKTIEVS-NRV-NDYLTINVKDYESTNSNRSIGKAVVPLSTID 1077

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BLAST of Synaptotagmin vs. Ensembl Nematostella
Match: EDO31746 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX17])

HSP 1 Score: 355.91 bits (912), Expect = 1.250e-118
Identity = 178/314 (56.69%), Postives = 242/314 (77.07%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFK-VPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDG---EKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            VD ++ Q+ G SY+EK+QP ++ELD N ED         V +G++ ++LDY F    LTVG+I+A D+PA D SG+SDPYVK+ LLPDKKKK+ETKVHRK LNPVFNE FVFK +P++E+ ++ L+  ++DFDRFS+HD IG+ ++PL  +DL   I EW+ L  P   G     ++ LGDICFSLRYVP+SGKL I I+EAK+LK MD+ G SDPYVK++L+  G+++KKKKTT+KK TLNPYYNE+F+F V FE+I++ +LI++V+DYDR+G SE IG+ V+G  ++GA+LRHW+DMLA+PRR +AQWHTL 
Sbjct:   45 VDFRAVQI-GASYQEKVQPSMDELDYNSEDYHS-DLSSGVKIGRINFTLDYSFTDNTLTVGIIRAEDIPAKDFSGSSDPYVKIMLLPDKKKKYETKVHRKTLNPVFNEQFVFKNIPYSEITNRILLMELFDFDRFSRHDLIGEARLPLIDVDLASNINEWRVLTPPSGSGGAGHSKSDLGDICFSLRYVPSSGKLQITIVEAKSLKSMDLTGYSDPYVKIALVQEGRKIKKKKTTVKKRTLNPYYNETFTFTVAFEKIEQTSLIISVLDYDRVGKSEMIGKCVVGELSSGADLRHWADMLASPRRSVAQWHTLH 356

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BLAST of Synaptotagmin vs. Ensembl Nematostella
Match: EDO43704 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXY7])

HSP 1 Score: 246.128 bits (627), Expect = 2.374e-77
Identity = 134/274 (48.91%), Postives = 191/274 (69.71%), Query Frame = 3

Query:  462 HLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFK-VPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENR--LGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQE 1274
             LGK+ +SL Y      LT+ V++A  LPA D SGTSDP+VK+ LLPDKK K ET+V RK LNPV+NE F F+  P N++  KTL   V D+DRFS++D IG++++PL  IDLG V   + +   P     K++R  LGD+  SL Y PT+ ++ +V+++A  LK MD+ G SDPYVK+ +M   +R+ KKKTTIK+ T +P +NESF F+VP ++I+ +  +  V+DYDRI  +E IG+++LG   TG+ LRHW++M+ NPR+P+AQWH LQ+
Sbjct:    2 QLGKIFFSLTYYSSDSVLTLKVLKAQGLPAKDFSGTSDPFVKIMLLPDKKHKLETRVKRKNLNPVWNEVFTFEGFPHNKLMGKTLYMQVLDYDRFSRNDPIGEVEIPLENIDLGPVTLTFTKDLLPC----KKDRVPLGDLLVSLMYQPTNNRIIVVVMKANKLKAMDLTGSSDPYVKMYIMHKDRRLDKKKTTIKRRTRDPVWNESFIFDVPLDKIRDLTFVFNVMDYDRITQNELIGQVILGYRTTGSSLRHWTEMMNNPRKPVAQWHRLQD 271

HSP 2 Score: 98.2117 bits (243), Expect = 7.575e-23
Identity = 54/145 (37.24%), Postives = 88/145 (60.69%), Query Frame = 3

Query:  447 EKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKK--KFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKE-LESPENDGEKENRLGD 872
            +K+ V LG L  SL Y      + V V++A  L AMD++G+SDPYVK+Y++   ++  K +T + R+  +PV+NE+F+F VP +++   T +FNV D+DR ++++ IGQ  V LG    G  +  W E + +P     + +RL D
Sbjct:  129 KKDRVPLGDLLVSLMYQPTNNRIIVVVMKANKLKAMDLTGSSDPYVKMYIMHKDRRLDKKKTTIKRRTRDPVWNESFIFDVPLDKIRDLTFVFNVMDYDRITQNELIGQ--VILGYRTTGSSLRHWTEMMNNPRKPVAQWHRLQD 271

[Close]

BLAST of Synaptotagmin vs. Ensembl Nematostella
Match: EDO50013 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF18])

HSP 1 Score: 175.252 bits (443), Expect = 2.520e-50
Identity = 109/288 (37.85%), Postives = 177/288 (61.46%), Query Frame = 3

Query:  423 MEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQI----KVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAK-NLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNA-TGAELRHWSDMLANPRRPIAQWHTL 1268
            M D  G   ++ +  GKL++S+ YD     L V V++A +L   + +     YV+++LLPDK +K++T V  K  NPVFNETF F V F+E+  +TL F + D+D +S+H  +G++     V +   +   VI E           E + R G++  SL Y+PTSG+LT V+L+A+ +++ +    LSDP+VK+SLM++G+++KK KT++   TL P YNE+F F++P E++  V+L+V ++  D     + I + V+G ++ T   L HW+ M+ +PR+PIAQWH L
Sbjct:    1 MSDCNGNPFEQSLGCGKLEFSIMYDTTCECLRVRVLKANNLSVPEATT----YVEVFLLPDKIEKYQTNVKYKNSNPVFNETFEFDVAFSELPERTLQFCINDYDGYSRHQALGEVFHSFDVNVNMQEDTVVIYEKDIRRDIFTFRENQVRKGEVLLSLCYLPTSGRLTFVVLKARLSMRLLFRYSLSDPFVKVSLMVSGRQIKKTKTSVMHGTLRPVYNEAFVFDIPVERLSDVSLLVRMLHSDG-KRCQTIAKTVVGPDSQTSIGLHHWNCMMTSPRKPIAQWHPL 283

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BLAST of Synaptotagmin vs. Ensembl Nematostella
Match: EDO41933 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S352])

HSP 1 Score: 166.007 bits (419), Expect = 9.644e-47
Identity = 106/292 (36.30%), Postives = 159/292 (54.45%), Query Frame = 3

Query:  423 MEDNEGVKEKEDVHL----GKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLP--DKKKKFETKVHRKILNPVFNETFVF-KVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEM 1277
            M   +G+ + +  HL    G L+++L Y      L V +  A  L  MD  GTSDPYVKL+LLP   K  K  +    K LNPVFNET  +  +   E++SKTL   V+D D   ++D IG+  + L  ++     + +K    P+      + LG I  +L+Y    G L + ++    L  MD  G SDPYVK  L  + ++  K++T I+K TLNP +NE F +++   ++ K +L VTV DYD   +++ IG ++L  NA G+ L+HW DML  P +   QWHTL+ +
Sbjct:    1 MSLEKGLCQSKTAHLCLGLGLLEFTLRYQKLDSRLDVVLHDAKGLKPMDHGGTSDPYVKLHLLPGASKSNKLRSHTKYKTLNPVFNETLTYYGITEEEISSKTLRLQVFDEDTIGRNDFIGETSINLKLLN-SNPTQTFKRSLIPKALDSPHSPLGRIQLALKYNTQRGMLFVTVMRCSGLASMDANGYSDPYVKCYLKPDPQKKSKRRTNIRKKTLNPEFNEEFVYDIAHHELAKKSLEVTVWDYDVGKSNDFIGGVILNINAEGSALKHWYDMLKGPNQLHTQWHTLENV 291

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BLAST of Synaptotagmin vs. Ensembl Nematostella
Match: EDO47762 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKX9])

HSP 1 Score: 162.155 bits (409), Expect = 2.595e-45
Identity = 102/279 (36.56%), Postives = 160/279 (57.35%), Query Frame = 3

Query:  462 HLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMS-GTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESP-ENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTV------VDYDRIGTSEPIGRIVLG--CNATGAELRHWSDMLANPRRPIAQWHTL 1268
            H+G+L +++ Y      L V +++A +LP+   +  T DP+VK+ LLP  K   +++  RK   P FNETF   +  +E+ S TL F V+D  R S+   IG+   PL  ++   + E W++LE P E    K   LGDI  SL Y PT  +LTI+IL A NL+ +   G +DP+VK++  +  K +K KKT + + T+NP +N++F++ V  + +   +L+V+V      V  D++     IGR++LG    A G E  HW++M+ NPR+ I  WH L
Sbjct:   29 HIGRLWFNIQYSTTGQNLVVTLVKARNLPSRSKTVRTCDPFVKIALLPKDKHVSQSRCKRKTKRPTFNETFYIPIAEDELDSSTLQFTVFDGYRMSQQAIIGEAMYPLIDMESTGIQELWRDLEKPIEVSQAKRKLLGDIHISLSYYPTLDRLTIIILRAANLRTIGHKG-TDPFVKIAFSIGNKVMKTKKTAVHQDTVNPMFNDAFNYTVTEDDLGTSSLLVSVWHSGGGVREDKL-----IGRVLLGGMMYARGKECEHWTEMMTNPRKMIKYWHPL 301

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BLAST of Synaptotagmin vs. Ensembl Medaka
Match: syt1a (synaptotagmin 1 [Source:NCBI gene;Acc:101166921])

HSP 1 Score: 406.757 bits (1044), Expect = 3.764e-137
Identity = 204/292 (69.86%), Postives = 242/292 (82.88%), Query Frame = 3

Query:  399 DLEELDANMEDNEGVKE-KEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            D E+ +  + + E   E KE   LGKLQYSLDY+F +  L VG+IQA +LPAMDM GTSDPYVK+YLLPDKKKKFETKVHRK LNPVFNE F FKVP+ E+  KTL+  VYDFDRFSKHD IG IKVP+  +D   V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+V+LEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV +++TV+DYD+IG ++ IG++ +G N++G ELRHWSDMLANPRRPIAQWH L+
Sbjct:  120 DEEDAETGLTETEKEAEPKESEKLGKLQYSLDYNFTENTLMVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYVELGGKTLVMTVYDFDRFSKHDAIGDIKVPMNKVDFSHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQIVITVLDYDKIGKNDAIGKVFVGLNSSGTELRHWSDMLANPRRPIAQWHVLK 409

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Query:  399 DLEELDANMEDNEGVKE-KEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            D E+ +  + + E   E KE   LGKLQYSLDY+F +  L VG+IQA +LPAMDM GTSDPYVK+YLLPDKKKKFETKVHRK LNPVFNE F FKVP+ E+  KTL+  VYDFDRFSKHD IG IKVP+  +D   V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+V+LEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV +++TV+DYD+IG ++ IG++ +G N++G ELRHWSDMLANPRRPIAQWH L+
Sbjct:  120 DEEDAETGLTETEKEAEPKESEKLGKLQYSLDYNFTENTLMVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYVELGGKTLVMTVYDFDRFSKHDAIGDIKVPMNKVDFSHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQIVITVLDYDKIGKNDAIGKVFVGLNSSGTELRHWSDMLANPRRPIAQWHVLK 409

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Query:  399 DLEELDANMEDNEGVKE-KEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            D E+ +  + + E   E KE   LGKLQYSLDY+F +  L VG+IQA +LPAMDM GTSDPYVK+YLLPDKKKKFETKVHRK LNPVFNE F FKVP+ E+  KTL+  VYDFDRFSKHD IG IKVP+  +D   V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+V+LEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV +++TV+DYD+IG ++ IG++ +G N++G ELRHWSDMLANPRRPIAQWH L+
Sbjct:  120 DEEDAETGLTETEKEAEPKESEKLGKLQYSLDYNFTENTLMVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYVELGGKTLVMTVYDFDRFSKHDAIGDIKVPMNKVDFSHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQIVITVLDYDKIGKNDAIGKVFVGLNSSGTELRHWSDMLANPRRPIAQWHVLK 409

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BLAST of Synaptotagmin vs. Ensembl Medaka
Match: syt1a (synaptotagmin 1 [Source:NCBI gene;Acc:101166921])

HSP 1 Score: 406.757 bits (1044), Expect = 1.684e-135
Identity = 204/292 (69.86%), Postives = 242/292 (82.88%), Query Frame = 3

Query:  399 DLEELDANMEDNEGVKE-KEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQ 1271
            D E+ +  + + E   E KE   LGKLQYSLDY+F +  L VG+IQA +LPAMDM GTSDPYVK+YLLPDKKKKFETKVHRK LNPVFNE F FKVP+ E+  KTL+  VYDFDRFSKHD IG IKVP+  +D   V EEW++L+S E   E++ +LGDICFSLRYVPT+GKLT+V+LEAKNLKKMDVGGLSDPYVK+ LM NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQKV +++TV+DYD+IG ++ IG++ +G N++G ELRHWSDMLANPRRPIAQWH L+
Sbjct:  234 DEEDAETGLTETEKEAEPKESEKLGKLQYSLDYNFTENTLMVGIIQAAELPAMDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYVELGGKTLVMTVYDFDRFSKHDAIGDIKVPMNKVDFSHVTEEWRDLQSAEK--EEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQIVITVLDYDKIGKNDAIGKVFVGLNSSGTELRHWSDMLANPRRPIAQWHVLK 523

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BLAST of Synaptotagmin vs. Ensembl Medaka
Match: syt2a (synaptotagmin-2 [Source:NCBI gene;Acc:101161806])

HSP 1 Score: 387.111 bits (993), Expect = 3.114e-129
Identity = 194/283 (68.55%), Postives = 238/283 (84.10%), Query Frame = 3

Query:  465 LGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN**CSFDAL 1313
            LGKLQYS+DYDFQ+ +LTVG++QA DL +MD  GTSDPYVK+++LPDKKKKF+TKVH+K LNPVFNETF FK+PF E+  KTL+ +VYDFDRFSKHD IG+IK+P+  +DL + IEEW++L+S   D E+  +LGDIC SLRYVPT+GKLTI ILEAKNLKKMDVGGLSDPYVK++L+ NGKR+KKKKTT+KK TLNPYYNESFSFE+P EQ+QK+  ++TV+DYD+IG ++ IG+I +G  +TGA L+HWSDMLANPRRPIAQWH LQ  PE     S  AL
Sbjct:  150 LGKLQYSIDYDFQENKLTVGILQAADLLSMDSGGTSDPYVKVFVLPDKKKKFDTKVHKKTLNPVFNETFTFKIPFQEMGGKTLVMSVYDFDRFSKHDVIGEIKIPMNTLDLAKPIEEWRDLDSA--DQEEPEKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDPYVKINLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPLEQMQKIQAVITVLDYDKIGKNDAIGKIWVGSKSTGAGLKHWSDMLANPRRPIAQWHPLQ--PEEEVDASLAAL 428

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BLAST of Synaptotagmin vs. Planmine SMEST
Match: SMESG000025329.1 (SMESG000025329.1)

HSP 1 Score: 684.485 bits (1765), Expect = 0.000e+0
Identity = 395/395 (100.00%), Postives = 395/395 (100.00%), Query Frame = 3

Query:  105 MKNSTHGSDHSASKASMKTNVEKFWHDLGKKLHMDPKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            MKNSTHGSDHSASKASMKTNVEKFWHDLGKKLHMDPKALIGVTIGLGILFLLFLYCLCKKCVFKRRKKKETAKKGAKGVVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN
Sbjct:    1 MKNSTHGSDHSASKASMKTNVEKFWHDLGKKLHMDPKALIGVTIGLGILFLLFLYCLCKKCVFKRRKKKETAKKGAKGVVDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 395

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BLAST of Synaptotagmin vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1)

HSP 1 Score: 568.926 bits (1465), Expect = 0.000e+0
Identity = 282/316 (89.24%), Postives = 305/316 (96.52%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLGN+YKEK+QPDLEELDANMEDNEG ++KE V+LGKLQYSLDYDF KGELTVGV+QATDLPAMDMSGTSDPYVK++LLPDKKKKFETKVHRKILNPVFNETFVFK+P++EV SKTL+FNV+DFDRFSKHDQIGQI++PLG++DL +VIEEWKEL  P++D EKENRLGDICFSLRYVPTSGKL IVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGR+VLGCNATGAELRHWSDMLANPRRPIAQWHTLQ+MPE +
Sbjct:  105 VDMKSVQLLGNAYKEKVQPDLEELDANMEDNEGAQDKEAVNLGKLQYSLDYDFTKGELTVGVVQATDLPAMDMSGTSDPYVKVFLLPDKKKKFETKVHRKILNPVFNETFVFKIPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEWKELGPPDSDNEKENRLGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRVVLGCNATGAELRHWSDMLANPRRPIAQWHTLQDMPEKS 420

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BLAST of Synaptotagmin vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1)

HSP 1 Score: 568.54 bits (1464), Expect = 0.000e+0
Identity = 282/316 (89.24%), Postives = 305/316 (96.52%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN 1289
            VDMKS QLLGN+YKEK+QPDLEELDANMEDNEG ++KE V+LGKLQYSLDYDF KGELTVGV+QATDLPAMDMSGTSDPYVK++LLPDKKKKFETKVHRKILNPVFNETFVFK+P++EV SKTL+FNV+DFDRFSKHDQIGQI++PLG++DL +VIEEWKEL  P++D EKENRLGDICFSLRYVPTSGKL IVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGR+VLGCNATGAELRHWSDMLANPRRPIAQWHTLQ+MPE +
Sbjct:   93 VDMKSVQLLGNAYKEKVQPDLEELDANMEDNEGAQDKEAVNLGKLQYSLDYDFTKGELTVGVVQATDLPAMDMSGTSDPYVKVFLLPDKKKKFETKVHRKILNPVFNETFVFKIPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEWKELGPPDSDNEKENRLGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRVVLGCNATGAELRHWSDMLANPRRPIAQWHTLQDMPEKS 408

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BLAST of Synaptotagmin vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1)

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 282/314 (89.81%), Postives = 304/314 (96.82%), Query Frame = 3

Query:  342 VDMKSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPE 1283
            VDMKS QLLGN+YKEK+QPDLEELDANMEDNEG ++KE V+LGKLQYSLDYDF KGELTVGV+QATDLPAMDMSGTSDPYVK++LLPDKKKKFETKVHRKILNPVFNETFVFK+P++EV SKTL+FNV+DFDRFSKHDQIGQI++PLG++DL +VIEEWKEL  P++D EKENRLGDICFSLRYVPTSGKL IVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGR+VLGCNATGAELRHWSDMLANPRRPIAQWHTLQ+MPE
Sbjct:   89 VDMKSVQLLGNAYKEKVQPDLEELDANMEDNEGAQDKEAVNLGKLQYSLDYDFTKGELTVGVVQATDLPAMDMSGTSDPYVKVFLLPDKKKKFETKVHRKILNPVFNETFVFKIPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEWKELGPPDSDNEKENRLGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPYVKLSLMLNGKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRVVLGCNATGAELRHWSDMLANPRRPIAQWHTLQDMPE 402

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BLAST of Synaptotagmin vs. Planmine SMEST
Match: SMESG000021478.1 (SMESG000021478.1)

HSP 1 Score: 461.07 bits (1185), Expect = 8.638e-159
Identity = 231/311 (74.28%), Postives = 275/311 (88.42%), Query Frame = 3

Query:  351 KSAQLLGNSYKEKIQPDLEELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAMDMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVASKTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEKENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLNGXXXXXXXXXXXXXXLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPE 1283
            K+ +++G +   K Q D E+L  + +D+   KE+E  +LGKL+Y LDYDF KGELTVG++QA +LPA+DM+GTSDPYVK++L PDKKKKFETKVHRK LNPVF+E F+FKVPF E+ SKTL  ++YDFDRFSKHDQIGQ+++PLG+IDL +V++EWKELE  ++  EKEN+LGDICFSLRYVPT+GKLT+V+LEAKNLKKMDVGGLSDPYVK+SLM+NGKR+KKKKTTIKK TLNPYYNESFSFEVPFEQIQ++NLIVTVVDYDRIGTSEPIGR+VLGCNA+G  LR WSDMLANPRRPIAQW TLQEMPE
Sbjct:   90 KNMKIIGGAVDNKTQSDEEDLVLDKDDDNEKKEEEKEYLGKLEYKLDYDFTKGELTVGILQAQELPALDMNGTSDPYVKVFLKPDKKKKFETKVHRKTLNPVFDEVFLFKVPFAEITSKTLCLHIYDFDRFSKHDQIGQLEIPLGSIDLCQVVQEWKELEPSKDSAEKENKLGDICFSLRYVPTNGKLTVVVLEAKNLKKMDVGGLSDPYVKISLMMNGKRIKKKKTTIKKCTLNPYYNESFSFEVPFEQIQRINLIVTVVDYDRIGTSEPIGRVVLGCNASGTALRQWSDMLANPRRPIAQWQTLQEMPE 400

The following BLAST results are available for this feature:

BLAST of Synaptotagmin vs. Ensembl Human
BLAST of Synaptotagmin vs. Ensembl Celegans
BLAST of Synaptotagmin vs. Ensembl Fly
BLAST of Synaptotagmin vs. Ensembl Zebrafish
BLAST of Synaptotagmin vs. Ensembl Xenopus
BLAST of Synaptotagmin vs. Ensembl Mouse
BLAST of Synaptotagmin vs. UniProt/SwissProt
BLAST of Synaptotagmin vs. TrEMBL
BLAST of Synaptotagmin vs. Ensembl Cavefish
BLAST of Synaptotagmin vs. Ensembl Sea Lamprey
BLAST of Synaptotagmin vs. Ensembl Yeast
BLAST of Synaptotagmin vs. Ensembl Nematostella
BLAST of Synaptotagmin vs. Ensembl Medaka
BLAST of Synaptotagmin vs. Planmine SMEST

BLAST of Synaptotagmin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SYT1	1.126e-139	68.49	synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509...	[more]
SYT1	1.126e-139	68.49	synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509...	[more]
SYT1	1.126e-139	68.49	synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509...	[more]
SYT1	4.796e-139	75.84	synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509...	[more]
SYT2	4.066e-135	72.59	synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:11510...	[more]

BLAST of Synaptotagmin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snt-1	1.113e-141	71.29	Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:...	[more]
snt-1	2.454e-130	67.08	Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:...	[more]
snt-3	1.716e-117	64.55	SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5...	[more]
snt-3	1.716e-117	64.55	SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5...	[more]
snt-2	6.169e-93	52.52	Synaptotagmin 2 [Source:UniProtKB/Swiss-Prot;Acc:...	[more]

BLAST of Synaptotagmin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Syt1	1.072e-155	70.98	gene:FBgn0004242 transcript:FBtr0077726	[more]
Syt1	6.148e-155	70.98	gene:FBgn0004242 transcript:FBtr0343993	[more]
Syt1	7.713e-155	70.66	gene:FBgn0004242 transcript:FBtr0332218	[more]
Syt1	1.554e-152	70.66	gene:FBgn0004242 transcript:FBtr0077728	[more]
Syt1	1.554e-152	70.66	gene:FBgn0004242 transcript:FBtr0345331	[more]

BLAST of Synaptotagmin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
syt1a	1.280e-135	73.23	synaptotagmin Ia [Source:ZFIN;Acc:ZDB-GENE-040718-...	[more]
syt1a	1.280e-135	73.23	synaptotagmin Ia [Source:ZFIN;Acc:ZDB-GENE-040718-...	[more]
syt2a	4.286e-125	68.40	synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
syt2a	4.286e-125	68.40	synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
syt5a	6.134e-124	67.67	synaptotagmin Va [Source:ZFIN;Acc:ZDB-GENE-040718-...	[more]

BLAST of Synaptotagmin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SYT5	2.000e-150	70.74	synaptotagmin 5 [Source:NCBI gene;Acc:100493612]	[more]
SYT5	2.005e-150	70.74	synaptotagmin 5 [Source:NCBI gene;Acc:100493612]	[more]
e2f4	7.564e-140	67.95	E2F transcription factor 4 [Source:Xenbase;Acc:XB-...	[more]
luzp2	4.693e-132	71.32	leucine zipper protein 2 [Source:Xenbase;Acc:XB-GE...	[more]
syt8	1.941e-108	57.05	synaptotagmin 8 [Source:NCBI gene;Acc:100037878]	[more]

BLAST of Synaptotagmin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Syt1	4.302e-140	68.71	synaptotagmin I [Source:MGI Symbol;Acc:MGI:99667]	[more]
Syt1	4.302e-140	68.71	synaptotagmin I [Source:MGI Symbol;Acc:MGI:99667]	[more]
Syt2	2.304e-135	72.59	synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666]	[more]
Syt2	2.304e-135	72.59	synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666]	[more]
Syt5	1.154e-122	59.81	synaptotagmin V [Source:MGI Symbol;Acc:MGI:1926368...	[more]

BLAST of Synaptotagmin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P41823\|SY65_APLCA	2.452e-177	79.87	Synaptotagmin-1 OS=Aplysia californica OX=6500 GN=...	[more]
sp\|P21521\|SY65_DROME	1.075e-154	70.98	Synaptotagmin 1 OS=Drosophila melanogaster OX=7227...	[more]
sp\|P34693\|SYT1_CAEEL	1.416e-140	71.29	Synaptotagmin-1 OS=Caenorhabditis elegans OX=6239 ...	[more]
sp\|P46096\|SYT1_MOUSE	3.010e-139	68.71	Synaptotagmin-1 OS=Mus musculus OX=10090 GN=Syt1 P...	[more]
sp\|P21707\|SYT1_RAT	3.391e-139	68.71	Synaptotagmin-1 OS=Rattus norvegicus OX=10116 GN=S...	[more]

BLAST of Synaptotagmin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q9U8R6	0.000e+0	95.95	Djsyt protein OS=Dugesia japonica OX=6161 GN=Djsyt...	[more]
A0A267E333	0.000e+0	85.13	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267GS86	0.000e+0	85.13	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267E6V1	0.000e+0	85.44	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
R7U5Y9	0.000e+0	82.59	Synaptotagmin 1 variant OS=Capitella teleta OX=283...	[more]

BLAST of Synaptotagmin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
syt1a	4.113e-137	69.52	synaptotagmin 1 [Source:NCBI gene;Acc:103044539]	[more]
syt1a	4.375e-137	69.52	synaptotagmin 1 [Source:NCBI gene;Acc:103044539]	[more]
syt1b	3.101e-130	70.44	synaptotagmin Ib [Source:ZFIN;Acc:ZDB-GENE-060503-...	[more]
syt1b	3.317e-130	70.44	synaptotagmin Ib [Source:ZFIN;Acc:ZDB-GENE-060503-...	[more]
syt5b	2.267e-126	67.88	synaptotagmin-1-like [Source:NCBI gene;Acc:1030298...	[more]

BLAST of Synaptotagmin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
syt2a	3.859e-62	63.06	synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
syt2a	4.034e-62	60.95	synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
ENSPMAT00000006908.1	4.862e-57	65.47	pep scaffold:Pmarinus_7.0:GL476344:649897:653668:1...	[more]
SYT5	2.441e-55	52.50	synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513...	[more]
SYT6	5.048e-41	56.10	synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638...	[more]

BLAST of Synaptotagmin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
TCB3	1.284e-10	32.00	Cortical ER protein involved in ER-plasma membrane...	[more]
TCB1	2.782e-10	32.03	Lipid-binding ER protein involved in ER-plasma mem...	[more]
TCB2	2.075e-7	35.05	ER protein involved in ER-plasma membrane tetherin...	[more]

BLAST of Synaptotagmin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO31746	1.250e-118	56.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43704	2.374e-77	48.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO50013	2.520e-50	37.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41933	9.644e-47	36.30	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47762	2.595e-45	36.56	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Synaptotagmin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
syt1a	3.764e-137	69.86	synaptotagmin 1 [Source:NCBI gene;Acc:101166921]	[more]
syt1a	3.764e-137	69.86	synaptotagmin 1 [Source:NCBI gene;Acc:101166921]	[more]
syt1a	3.764e-137	69.86	synaptotagmin 1 [Source:NCBI gene;Acc:101166921]	[more]
syt1a	1.684e-135	69.86	synaptotagmin 1 [Source:NCBI gene;Acc:101166921]	[more]
syt2a	3.114e-129	68.55	synaptotagmin-2 [Source:NCBI gene;Acc:101161806]	[more]

BLAST of Synaptotagmin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000025329.1	0.000e+0	100.00	SMESG000025329.1	[more]
SMESG000055143.1	0.000e+0	89.24	SMESG000055143.1	[more]
SMESG000055143.1	0.000e+0	89.24	SMESG000055143.1	[more]
SMESG000055143.1	0.000e+0	89.81	SMESG000055143.1	[more]
SMESG000021478.1	8.638e-159	74.28	SMESG000021478.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30022907 ID=SMED30022907|Name=Synaptotagmin|organism=Schmidtea mediterranea sexual|type=transcript|length=1814bp
ATTTATTGAAAATTATTTTTTCTATTATTAGGAGAAAATTGATTATTTTT
TTTTGACAAAATAAGTTTTGGATATATTTCCCATTTGTTTGTATTCGTAA
ACCAATGAAGAATTCGACTCACGGATCGGATCATTCGGCCAGCAAGGCCA
GTATGAAAACGAATGTGGAAAAATTTTGGCATGATCTCGGAAAAAAATTG
CACATGGATCCAAAAGCATTAATAGGAGTAACAATCGGTTTGGGAATATT
GTTTTTGTTGTTCCTTTATTGCTTATGTAAAAAATGTGTTTTCAAGCGTC
GAAAAAAGAAGGAAACGGCCAAAAAAGGAGCCAAGGGAGTAGTCGATATG
AAAAGTGCCCAATTGTTGGGGAATTCATATAAAGAAAAAATTCAACCCGA
TCTTGAAGAACTTGATGCAAACATGGAAGACAATGAAGGTGTAAAAGAAA
AAGAAGATGTTCATTTAGGAAAATTACAATATTCTCTAGATTATGATTTT
CAGAAAGGAGAATTAACTGTTGGAGTTATTCAAGCAACTGATCTTCCAGC
TATGGATATGTCAGGAACATCAGATCCATATGTCAAATTATACCTTCTCC
CAGACAAGAAAAAGAAATTCGAAACAAAGGTTCATAGGAAAATTTTAAAT
CCTGTATTCAATGAAACTTTTGTTTTCAAAGTTCCTTTCAATGAAGTTGC
ATCGAAGACTTTGATTTTCAACGTTTATGACTTTGACAGATTTTCCAAAC
ACGATCAAATCGGTCAAATAAAAGTACCATTGGGAGCTATAGATTTAGGT
CGAGTTATTGAAGAATGGAAGGAACTGGAATCTCCAGAAAACGATGGGGA
AAAGGAAAACAGGTTGGGAGACATTTGTTTCTCTTTAAGATACGTACCGA
CATCTGGAAAGCTTACAATAGTCATTTTGGAAGCAAAGAATCTTAAAAAA
ATGGATGTCGGAGGATTGTCTGATCCATATGTTAAACTTTCCTTGATGCT
TAATGGTAAACGAGTGAAGAAGAAGAAAACTACCATCAAAAAGTATACAC
TAAATCCTTACTACAATGAATCATTTTCCTTTGAAGTACCATTCGAACAA
ATACAAAAAGTGAACTTGATCGTCACGGTTGTTGATTATGACAGAATCGG
AACCAGCGAACCGATAGGTAGAATTGTTCTGGGATGTAACGCAACTGGAG
CAGAATTGCGACATTGGTCGGATATGTTGGCAAATCCCCGGCGACCAATC
GCCCAGTGGCATACCCTCCAAGAGATGCCAGAGAACAATTGATAGTGTTC
GTTTGATGCTTTAAAGCGGTTTGCATAATTCGTGAAATAAGTTATCAAAA
TTTGAGAAATGTTTTTTTTTCTGAAACAAAAATGGCATGAGACAATATAC
CAGAGTTCATTAGTGTGTGGTTTCGTTGAATATTTTGGTGGTGTTGCATC
TTATCGTTTGTCCTCTAATCTAATAATGTTTTATTCTTTATATAGCTGAT
TTATTCTCGAGCGAAACATTTTTTATGTGTACCAAAATACTTATGTCATA
GCCATTGTGATTAGTCTGTAAACTATTGCGTAATAGCCCCTCTCATTGGC
TTTTTTTAAGAGTAGTGAGTTGGAAAAAAAAATACAAAAATGACTTCAAT
TGTTAAACATTACTCATATTTTATCAGTAAGTTAACTTGCATATTTGCAG
TTAATTATGGCATTTTATCTCTAAATCTCTGAAGCATGGCCTCAAGTCTT
TTGTTTGTTTTAATGTAATTATGTCTAGATGAGAATATTAAAATACTTCG
GTTTATATAAAAGA

protein sequence of SMED30022907-orf-1

>SMED30022907-orf-1 ID=SMED30022907-orf-1|Name=SMED30022907-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=396bp
MKNSTHGSDHSASKASMKTNVEKFWHDLGKKLHMDPKALIGVTIGLGILF
LLFLYCLCKKCVFKRRKKKETAKKGAKGVVDMKSAQLLGNSYKEKIQPDL
EELDANMEDNEGVKEKEDVHLGKLQYSLDYDFQKGELTVGVIQATDLPAM
DMSGTSDPYVKLYLLPDKKKKFETKVHRKILNPVFNETFVFKVPFNEVAS
KTLIFNVYDFDRFSKHDQIGQIKVPLGAIDLGRVIEEWKELESPENDGEK
ENRLGDICFSLRYVPTSGKLTIVILEAKNLKKMDVGGLSDPYVKLSLMLN
GKRVKKKKTTIKKYTLNPYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGT
SEPIGRIVLGCNATGAELRHWSDMLANPRRPIAQWHTLQEMPENN*

Aliases

The feature 'Synaptotagmin' has the following synonyms


Synonym
Dj-syt

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000080	peripheral nervous system
PLANA:0000418	head
PLANA:0000463	cholinergic neuron
PLANA:0000464	GABAergic neuron
PLANA:0004519	embryonic pharynx neuron
PLANA:0000025	nervous system
PLANA:0000465	pharynx nerve plexus
PLANA:0000099	neuron
PLANA:0000044	cephalic ganglia
PLANA:0000097	ventral nerve cord
PLANA:0000058	embryonic digestive system
PLANA:0000023	embryonic pharynx

Vocabulary: **INTERPRO**
Term	Definition
IPR035892	C2_domain_sf
IPR015428	Synaptotagmin1
IPR000008	C2_dom
IPR001565	Synaptotagmin

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0000149	SNARE binding
GO:0005509	calcium ion binding
GO:0005544	calcium-dependent phospholipid binding
GO:0046872	metal ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0008021	synaptic vesicle
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0030285	integral component of synaptic vesicle membrane
GO:0030672	synaptic vesicle membrane
GO:0031410	cytoplasmic vesicle
GO:0045202	synapse

Vocabulary: **biological process**
Term	Definition
GO:0007269	neurotransmitter secretion
GO:0016079	synaptic vesicle exocytosis
GO:0045955	negative regulation of calcium ion-dependent exocytosis

Vocabulary: **Schmidtea mediterranea Developmental Stages**
Term	Definition
PLANA:0000007	Stage 7
PLANA:0000004	Stage 4
PLANA:0000006	Stage 6
PLANA:0000008	Stage 8
PLANA:0000003	Stage 3
PLANA:0000005	Stage 5

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001565	Synaptotagmin	PRINTS	PR00399	SYNAPTOTAGMN	coord: 139..152 score: 48.53 coord: 214..224 score: 46.79 coord: 124..139 score: 47.61 coord: 194..209 score: 36.58
IPR000008	C2 domain	PRINTS	PR00360	C2DOMAIN	coord: 179..192 score: 57.48 coord: 152..164 score: 59.66 coord: 203..211 score: 48.45
IPR000008	C2 domain	SMART	SM00239	C2_3c	coord: 136..238 e-value: 6.0E-22 score: 88.9 coord: 269..383 e-value: 1.3E-23 score: 94.5
IPR000008	C2 domain	PFAM	PF00168	C2	coord: 268..372 e-value: 4.2E-23 score: 81.6 coord: 135..241 e-value: 3.9E-30 score: 104.2
IPR000008	C2 domain	PROSITE	PS50004	C2	coord: 267..358 score: 20.698
IPR000008	C2 domain	PROSITE	PS50004	C2	coord: 136..223 score: 20.298
IPR035892	C2 domain superfamily	GENE3D	G3DSA:2.60.40.150		coord: 248..394 e-value: 1.7E-54 score: 185.7
IPR035892	C2 domain superfamily	GENE3D	G3DSA:2.60.40.150		coord: 107..247 e-value: 1.3E-48 score: 166.5
None	No IPR available	PANTHER	PTHR10024	SYNAPTOTAGMIN	coord: 3..391
None	No IPR available	CDD	cd08385	C2A_Synaptotagmin-1-5-6-9-10	coord: 121..243 e-value: 7.502E-86 score: 254.497
None	No IPR available	CDD	cd08402	C2B_Synaptotagmin-1	coord: 254..389 e-value: 2.11899E-91 score: 269.271
None	No IPR available	SUPERFAMILY	SSF49562	C2 domain (Calcium/lipid-binding domain, CaLB)	coord: 115..246
None	No IPR available	SUPERFAMILY	SSF49562	C2 domain (Calcium/lipid-binding domain, CaLB)	coord: 254..389
None	No IPR available	TMHMM	TMhelix		coord: 38..57
IPR015428	Synaptotagmin 1	PANTHER	PTHR10024:SF239	SYNAPTOTAGMIN-1	coord: 3..391