Dihydropyrimidinase

Overview


Name	Dihydropyrimidinase
Smed ID	SMED30022905
Length (bp)	1893

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Dihydropyrimidinase (SMED30022905) t-SNE clustered cells

Violin plots show distribution of expression levels for Dihydropyrimidinase (SMED30022905) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dihydropyrimidinase (SMED30022905) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dihydropyrimidinase (SMED30022905) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30022905

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30022905	SMESG000028784.1 SMESG000061889.1	dd_Smed_v4_3519_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30022905	SMESG000028784.1 SMESG000061889.1	dd_Smed_v4_3519_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30022905	SMESG000028784.1 SMESG000061889.1	dd_Smed_v4_3519_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30022905	SMESG000028784.1 SMESG000061889.1	dd_Smed_v4_3519_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30022905	SMESG000028784.1 SMESG000061889.1	dd_Smed_v4_3519_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30022905	SMESG000028784.1 SMESG000061889.1	dd_Smed_v4_3519_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30022905	SMESG000028784.1 SMESG000061889.1	dd_Smed_v4_3519_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30022905	SMESG000028784.1	Contig51130	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30022905	SMESG000028784.1	Contig51130	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30022905	SMESG000028784.1	Contig35346	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30022905	SMESG000028784.1	Contig35346	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
head region	SMED30022905	SMESG000028784.1 SMESG000061889.1	dd_Smed_v6_3519_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL5 (dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc:HGNC:20637])

HSP 1 Score: 309.301 bits (791), Expect = 7.487e-97
Identity = 200/579 (34.54%), Postives = 319/579 (55.09%), Query Frame = 1

Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAI-IRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKM-KRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVT--VDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            + N  ++++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL+IPGGID ST+F+   ++    D  ++ + AAL GGTT II  V       LV++ +  +     KV C+Y   V I     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GI+GPEG   SR  E E E  +R++ + +   C + +  V +     ++A  KM+G+ + +ET      L+   Y+  +W  +A+ +T PP+R D + +  + S+   D +++VAS+H   T   +++GK DF  IPHGVSGV++R+S++W+RGV  G ++E  FV+ TS+NAAK+ NLYP +G I  G+ AD+V+W+P  T+TISA +Q    D N++E + C GVP V I  G V ++   F+    TG+   L+     V  K+ +R + L+  G         D      ++  + +P K   K++ T   D+   P+        GG R++ +SSFSLSGSQIDD  P R++ R   PPGG+S+ I+
Sbjct:    2 LANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRG--------VDRTPYLGDVAVVVHPGK---KEMGTPLADTPTRPVTRH-----GGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564

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Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAI-IRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKM-KRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVT--VDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            + N  ++++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL+IPGGID ST+F+   ++    D  ++ + AAL GGTT II  V       LV++ +  +     KV C+Y   V I     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GI+GPEG   SR  E E E  +R++ + +   C + +  V +     ++A  KM+G+ + +ET      L+   Y+  +W  +A+ +T PP+R D + +  + S+   D +++VAS+H   T   +++GK DF  IPHGVSGV++R+S++W+RGV  G ++E  FV+ TS+NAAK+ NLYP +G I  G+ AD+V+W+P  T+TISA +Q    D N++E + C GVP V I  G V ++   F+    TG+   L+     V  K+ +R + L+  G         D      ++  + +P K   K++ T   D+   P+        GG R++ +SSFSLSGSQIDD  P R++ R   PPGG+S+ I+
Sbjct:    2 LANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRG--------VDRTPYLGDVAVVVHPGK---KEMGTPLADTPTRPVTRH-----GGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564

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Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAI-IRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKM-KRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVT--VDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            + N  ++++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL+IPGGID ST+F+   ++    D  ++ + AAL GGTT II  V       LV++ +  +     KV C+Y   V I     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GI+GPEG   SR  E E E  +R++ + +   C + +  V +     ++A  KM+G+ + +ET      L+   Y+  +W  +A+ +T PP+R D + +  + S+   D +++VAS+H   T   +++GK DF  IPHGVSGV++R+S++W+RGV  G ++E  FV+ TS+NAAK+ NLYP +G I  G+ AD+V+W+P  T+TISA +Q    D N++E + C GVP V I  G V ++   F+    TG+   L+     V  K+ +R + L+  G         D      ++  + +P K   K++ T   D+   P+        GG R++ +SSFSLSGSQIDD  P R++ R   PPGG+S+ I+
Sbjct:    2 LANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRG--------VDRTPYLGDVAVVVHPGK---KEMGTPLADTPTRPVTRH-----GGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564

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BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL2 (dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014])

HSP 1 Score: 308.531 bits (789), Expect = 2.038e-96
Identity = 196/569 (34.45%), Postives = 309/569 (54.31%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+  ++++IPGGID  T F + P+      D     + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + ME L +  G+N F + +  +      +     VL   +++  + ++   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAK+FNLYP +G IAVGS AD+VIW+P   +TISA + +   + NIFEG+ C+G P VVI  G +  +     +   +G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K Q PP     RN+  S FSLSG+QIDD  P R+T R   PPGG++N+
Sbjct:   16 RLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQM-PDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTVTPASSAKTSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANI 568

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BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL2 (dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014])

HSP 1 Score: 309.686 bits (792), Expect = 1.017e-95
Identity = 197/575 (34.26%), Postives = 313/575 (54.43%), Query Frame = 1

Query:   16 LNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            +N ++ ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+  ++++IPGGID  T F + P+      D     + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + ME L +  G+N F + +  +      +     VL   +++  + ++   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAK+FNLYP +G IAVGS AD+VIW+P   +TISA + +   + NIFEG+ C+G P VVI  G +  +     +   +G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K Q PP     RN+  S FSLSG+QIDD  P R+T R   PPGG++N+
Sbjct:  115 INDQSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQM-PDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTVTPASSAKTSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANI 673

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BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-2 (Dihydropyrimidinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q18677])

HSP 1 Score: 265.388 bits (677), Expect = 5.515e-81
Identity = 172/467 (36.83%), Postives = 257/467 (55.03%), Query Frame = 1

Query:   31 MKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETL-ARQFGINCFQMTI---GNEINANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQD--AAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKF---QLNEFIGNATGERIDLKINCQVV 1389
            M +L+K G IVN D  F+SDVL+ +  I +I  SI  +   +V+D T++L+IPGGIDP T+  L       +D  H  + AA+AGGTT II  V    G  L+ +    +     KV+C+YG  + I     E  K ME +   ++GIN F+  +   G  +  +        +  +     RVH  + + +    E L+++GI+GPEG  QSR  E E E  +R   +     C L +  VM++  A  +A  + +G  +F E I   LA     Y++ +W  +A  +  PP+  D    +A+++ +  G++ + A+++ T     +S+GK DF  IP+GV+GVE+R+S++WD+GV +GII+   FV+ TST AAKIFN YP +G IAVGS ADIVIWN   TRTIS  + H   D NIFEG+   GVPE+ I  G   +   QL    G  +G+ I L  + Q+V
Sbjct:    1 MSLLIKNGTIVNDDAIFKSDVLVLDGRIVEIAPSIQPTPGLEVVDATDRLVIPGGIDPHTHMQLPFMGEIAKDDFHRGTEAAVAGGTTMIIDFVIPTKGESLLVAYDRWRGWADPKVVCDYGLSMAITSWGPEIAKEMEIVTGAEYGINSFKFFLAYAGVFMVRDEEFYQGMIQCAKLRALARVHAENGSVIAERCEHLLSSGITGPEGHTQSRPEELEAEATFRACTMASQANCPLYVVHVMSKGAAAAIAHHRKKGAVVFGEPIAAGLATDGSHYYNEDWLHAARYVMSPPLSRDPSTPSALMKLLAAGELHLTATDNCTFDCQQKSLGKDDFTKIPNGVNGVEDRMSVVWDKGVHAGIIDPMRFVAVTSTMAAKIFNCYPQKGRIAVGSDADIVIWNANATRTISKDTHHHAIDFNIFEGMQVHGVPEITISRGRTVWANGQLKTVQG--SGQFIPLAPDSQIV 465

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BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-1 (Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21773])

HSP 1 Score: 258.455 bits (659), Expect = 1.018e-78
Identity = 152/445 (34.16%), Postives = 243/445 (54.61%), Query Frame = 1

Query:   37 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXV------KEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETL-ARQFGINCFQMTIGNEINANTVSVX------XXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKF 1320
            +++K G +VN D  F++DVL+ N II ++  +I    DT+VID T++L+IPGGIDP T+  + P   ++  ++ +           T++        ++G  L+      +S    KV C+YG  V I     E  + M  + + +FG+N F+  +  E   NT+ V          +  +     RVH  + + ++  E +L+  G++GPEG  QSR  E E E   R   L     C + I  VM +  A  ++  + +G  +F E I   LAL    Y++ +W  +A  +  PP+  D      +++ +  G++ +  +++ T     +S+GK +F  IP+G++GVE+R+S++W++GV SGII+   +VS TS+ AAKIFN+YP +G IAVGS ADIVI+NP  TRTIS  + H   D NIFEGI+C GV EV I  G + +
Sbjct:    5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQM-PYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYE---NTLMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAISHHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNLDFNIFEGINCHGVAEVTISRGRIVW 445

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Query:   37 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXV------KEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETL-ARQFGINCFQMTIGNEINANTVSVX------XXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKF 1320
            +++K G +VN D  F++DVL+ N II ++  +I    DT+VID T++L+IPGGIDP T+  + P   ++  ++ +           T++        ++G  L+      +S    KV C+YG  V I     E  + M  + + +FG+N F+  +  E   NT+ V          +  +     RVH  + + ++  E +L+  G++GPEG  QSR  E E E   R   L     C + I  VM +  A  ++  + +G  +F E I   LAL    Y++ +W  +A  +  PP+  D      +++ +  G++ +  +++ T     +S+GK +F  IP+G++GVE+R+S++W++GV SGII+   +VS TS+ AAKIFN+YP +G IAVGS ADIVI+NP  TRTIS  + H   D NIFEGI+C GV EV I  G + +
Sbjct:    5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQM-PYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYE---NTLMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAISHHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNLDFNIFEGINCHGVAEVTISRGRIVW 445

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Query:   37 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXV------KEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETL-ARQFGINCFQMTIGNEINANTVSVX------XXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKF 1320
            +++K G +VN D  F++DVL+ N II ++  +I    DT+VID T++L+IPGGIDP T+  + P   ++  ++ +           T++        ++G  L+      +S    KV C+YG  V I     E  + M  + + +FG+N F+  +  E   NT+ V          +  +     RVH  + + ++  E +L+  G++GPEG  QSR  E E E   R   L     C + I  VM +  A  ++  + +G  +F E I   LAL    Y++ +W  +A  +  PP+  D      +++ +  G++ +  +++ T     +S+GK +F  IP+G++GVE+R+S++W++GV SGII+   +VS TS+ AAKIFN+YP +G IAVGS ADIVI+NP  TRTIS  + H   D NIFEGI+C GV EV I  G + +
Sbjct:    5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQM-PYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYE---NTLMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAISHHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNLDFNIFEGINCHGVAEVTISRGRIVW 445

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BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: unc-33 (pep chromosome:WBcel235:IV:3518147:3525572:1 gene:WBGene00006769.1 transcript:Y37E11C.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-33)

HSP 1 Score: 185.652 bits (470), Expect = 3.262e-50
Identity = 127/433 (29.33%), Postives = 231/433 (53.35%), Query Frame = 1

Query:   37 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDL-KSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNE 1332
            +L+K   IVN D  F +D+LIE+ II+ +  ++      +V+D   KL +P GID  T   ++ +  D L     +A+AGGT TI+ +V+ +    +V+++K +++ L KS + C+    V I    D C + M  L +  GIN F +   +  +   + + +  K L  L+++   + + +  +E++++  G++GPEGF QSR    E +++  +  L ++  C + I QV + D    + K +  G    +E    A+       FS +   +++ +TD P+R      +I ++    + +  S H  + +A R +  +DF     G +G EER++++W+R V+SG I+   FV+ TSTNAAK+FN+YP +G IAVG+ AD+VIW+    R + +       + ++++G++   V    IV G + +Q  E
Sbjct:  160 LLVKNAQIVNDDAIFVADILIEDGIIQNVAPNLEAPEGAEVLDAAGKLALPAGIDVYTQ--VTDSSVDDLSTGCKSAIAGGTGTIVEVVRPRGAESVVSAVKRVKNQLEKSGISCHVALSVAI---TDFCEQEMSELVKNEGINSFVLDGVSLTDDKLLELFEHVKRLGALIRVVPENKSIVAMLEKKMLKLGVTGPEGFPQSRPESLEADRVSGVCVLGNLASCPISIVQVSSADSLAAIEKARASGALAHAEIASAAVTADGSALFSQDLRFASAHLTDVPLRRGAPDRMIGALSTQPLVVCTSGHRPVNSATR-VAAKDFAIAQKGSTGAEERMAVVWERAVRSGRIDAMRFVAVTSTNAAKMFNMYPKKGRIAVGADADLVIWDASGKRVLESSRAQSSQENSMYDGLTVHSVVTATIVGGKIAYQNGE 586

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BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0114453)

HSP 1 Score: 254.218 bits (648), Expect = 7.219e-76
Identity = 184/593 (31.03%), Postives = 302/593 (50.93%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQS--IVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHR---DILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEI-----NANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNED--IAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQL-NEFIGNATGERIDLKINCQVVKD---------------KMKRYECLREFGKMG--------ITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSN 1698
            ++ +K G IVN D+ F++DV IE+ IIK +G S  I + G  + ID +  +IIPGGIDP T+  L        D  ++ + AA+AGGTT II  V       ++ +    +S    KV C+YG  V I        + +  L ++ G+N F+  +  +      +++ + V ++ + L  +  +   +   +    + L+  GI+GPEG   SR  E E E ++R   L H   C L +  VM++   I    A+ +  GR I  ET+  AL   +       +D  A+ +  PP+R D+     +++ +   D+ +  S++ T     +++GK DF  IP+GV+GVE+R+S++W++GV +G+++ C FV+ TSTNAAKIFN+YP +G IAVGS ADIVIWNP  TRTIS  + H   D NIFEG++  GV E V+V G +  +  N  +    G  I   +    V D               + +     + F ++         I+  ++ N+ + +E    + P         +V  +++           G R++Q+SSFS+  S+  D   +R+ I+  +PPGGKS+
Sbjct:   21 RVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTP---------SVRGRVD-----------GKRDLQESSFSI--SEELDRSGVRACIKVKNPPGGKSS 591

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BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0089686)

HSP 1 Score: 252.677 bits (644), Expect = 2.655e-75
Identity = 182/591 (30.80%), Postives = 300/591 (50.76%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQS--IVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHR---DILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEI-----NANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQL-NEFIGNATGERIDLKINCQVVKD---------------KMKRYECLREFGKMG--------ITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSN 1698
            ++ +K G IVN D+ F++DV IE+ IIK +G S  I + G  + ID +  +IIPGGIDP T+  L        D  ++ + AA+AGGTT II  V       ++ +    +S    KV C+YG  V I        + +  L ++ G+N F+  +  +      +++ + V ++ + L  +  +   +   +    + L+  GI+GPEG   SR  E E E ++R   L H     L +  + ++  A+LV + +  G  +F ET+  +L  S       +       IT PPIR   +    +++S+   D+ +  S++ T     +++GK DF  IP+GV+GVE+R+S++W++GV +G+++ C FV+ TSTNAAKIFN+YP +G IAVGS ADIVIWNP  TRTIS  + H   D NIFEG++  GV E V+V G +  +  N  +    G  I   +    V D               + +     + F ++         I+  ++ N+ + +E    + P         +V  +++           G R++Q+SSFS+  S+  D   +R+ I+  +PPGGKS+
Sbjct:   21 RVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQMKTPLFVSGLTSKSSAELVGRARRSGYCVFGETLASSLGRSMSAVPKGD---RIYAITSPPIRESAETPRQLMKSLAYDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTP---------SVRGRVD-----------GKRDLQESSFSI--SEELDRSGVRACIKVKNPPGGKSS 586

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BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0089685)

HSP 1 Score: 106.301 bits (264), Expect = 9.309e-25
Identity = 89/300 (29.67%), Postives = 147/300 (49.00%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQS--IVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHR---DILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEI-----NANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNED--IAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQ 897
            ++ +K G IVN D+ F++DV IE+ IIK +G S  I + G  + ID +  +IIPGGIDP T+  L        D  ++ + AA+AGGTT II  V       ++ +    +S    KV C+YG  V I        + +  L ++ G+N F+  +  +      +++ + V ++ + L  +  +   +   +    + L+  GI+GPEG   SR  E E E ++R   L H   C L +  VM++   I    A+ +  GR I  ET+  AL   +       +D  A+ +  PP+R D+
Sbjct:   21 RVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDK 320

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BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl5a (dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-GENE-030131-3136])

HSP 1 Score: 308.145 bits (788), Expect = 1.598e-96
Identity = 194/572 (33.92%), Postives = 311/572 (54.37%), Query Frame = 1

Query:   28 TMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPT-SGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            T+++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL++PGGID S + N   ++    D  ++ + AALAGGTT +I  V  +    L+++ +  +S   +K  C+Y   + +     +    METL R  G+N FQM +  +   +  ++                RVH  +   +     E +  GISGPEG   SR  E E E ++R + + +   C + +  V +     ++A  KM+G+ +  ET      L+  +Y+  +W  +A+ +T PP+R D +    ++  +    +++V S+H   T   +++GK DF  IPHGV GV++R+S++W+RGV  G ++E  FV+ TS+NAAKI+NLYP +G I  G+ AD+V+W+P  TRTIS  +Q    D N++E + C GVP V I  G V ++   F     +G+   L+     +  KM + E  +     G+ R          ++  + N  K   KD+   D  +NP    RP T  GG R++ +SSFSLSG+QIDD  P R++ R   PPGG+S+ I+
Sbjct:    7 TVRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLNESFMNGTTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKARSHADAKACCDYALHMGVTWWGPKARAQMETLVRDKGVNSFQMYMAYKDMYMLRDSELFQALQNCKDIGAVARVHAENGELVAEGAREALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLASAKMQGKVVHGETTTAHAVLNGMQYYHQDWAHAAAFVTVPPLRLDPNTPNYLLSLLGNDTLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSVMWERGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPESTRTISVTTQWQGGDVNLYENLRCHGVPLVTISRGRVVYENGIFTCAEGSGKFYPLRTFPDYLYKKMVQREKCQAL--KGVER-----TPYTGDVAAVQNSGK---KDLGPADGDMNP----RPCTRHGGVRDLHESSFSLSGAQIDDNVPKRASARILAPPGGRSSGIW 564

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Query:   28 TMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPT-SGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            T+++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL++PGGID S + N   ++    D  ++ + AALAGGTT +I  V  +    L+++ +  +S   +K  C+Y   + +     +    METL R  G+N FQM +  +   +  ++                RVH  +   +     E +  GISGPEG   SR  E E E ++R + + +   C + +  V +     ++A  KM+G+ +  ET      L+  +Y+  +W  +A+ +T PP+R D +    ++  +    +++V S+H   T   +++GK DF  IPHGV GV++R+S++W+RGV  G ++E  FV+ TS+NAAKI+NLYP +G I  G+ AD+V+W+P  TRTIS  +Q    D N++E + C GVP V I  G V ++   F     +G+   L+     +  KM + E  +     G+ R          ++  + N  K   KD+   D  +NP    RP T  GG R++ +SSFSLSG+QIDD  P R++ R   PPGG+S+ I+
Sbjct:    7 TVRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLNESFMNGTTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKARSHADAKACCDYALHMGVTWWGPKARAQMETLVRDKGVNSFQMYMAYKDMYMLRDSELFQALQNCKDIGAVARVHAENGELVAEGAREALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLASAKMQGKVVHGETTTAHAVLNGMQYYHQDWAHAAAFVTVPPLRLDPNTPNYLLSLLGNDTLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSVMWERGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPESTRTISVTTQWQGGDVNLYENLRCHGVPLVTISRGRVVYENGIFTCAEGSGKFYPLRTFPDYLYKKMVQREKCQAL--KGVER-----TPYTGDVAAVQNSGK---KDLGPADGDMNP----RPCTRHGGVRDLHESSFSLSGAQIDDNVPKRASARILAPPGGRSSGIW 564

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl4 (dihydropyrimidinase like 4 [Source:ZFIN;Acc:ZDB-GENE-050720-3])

HSP 1 Score: 306.22 bits (783), Expect = 1.094e-95
Identity = 195/572 (34.09%), Postives = 309/572 (54.02%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPST-----NFNLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNP-HKVIQ--KDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            K+++KGG IVN D+ F +D+ +E+ IIKQIG++++V    K +D    ++IPGGID +T     +  +SP   D  ++ + AALAGGTT II  V  + G+ L+++    +     +  C+Y   + I    D   + +E+L +  G+N F + +  +    +++T          +     +VH  +   +E  +++L+  GI+GPEG   S   E E E +YR + +     C L I +VM++  A L+AK + +G  I+ E I  +L      Y+S NW E+A+ +  PP+  D      +   + CGD+ + AS + T T A +++GK DF  IP G +G+EER+S++WD+ V +G ++E +FV+ TSTNAAKIFNLYP +G IAVGS ADIVIWN  +TRT SA + +L  + NIFEG+ C+G P +VI  G +  +     +   +G  I  K     V      Y+ ++   +M   R +             + P H VI   K +    +   P    + P  G  RN+  S F+LSG+Q+DD  P R+  +   PPGG+SN+
Sbjct:   16 KLIIKGGKIVNDDQSFYADIYVEDGIIKQIGENLIVPTGVKTVDAYGHIVIPGGIDVNTCLQAPHLGMSP--ADDFYHGTRAALAGGTTMIIDHVVPEPGSSLLSAFDQWKDTADKRSCCDYSLHIDITRWHDGLFEELESLVKDKGVNSFLIFMAYKDKFQSSDTQIYEMFSAMRELGAIAQVHAENGDIIEEEQKKLLDLGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSKPAADLIAKARKKGMVIYGEPIAASLGTDGSHYWSKNWAEAAAFVMSPPLNPDTSTPDYLNSLLSCGDLQVTASANCTFTTAQKAVGKDDFTFIPEGTNGIEERMSIVWDKAVATGKMDENDFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWNTKETRTFSAKTHNLTVEVNIFEGMECRGFPVLVISQGRIVLEDGTLSVMEGSGRFIPRKAYPDYV------YKRIKARSRMADARGVPRG--------NYDGPVHDVISMTKSVPATPTTRGPSCPGKTPL-GPTRNLHQSGFTLSGTQMDDHIPRRTAQKIVAPPGGRSNI 570

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BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl5a (dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-GENE-030131-3136])

HSP 1 Score: 305.449 bits (781), Expect = 2.111e-95
Identity = 194/584 (33.22%), Postives = 309/584 (52.91%), Query Frame = 1

Query:   28 TMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIG-----------------NEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPT-SGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            T+++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL++PGGID S + N   ++    D  ++ + AALAGGTT +I  V  +    L+++ +  +S   +K  C+Y   + +     +    METL R  G+N FQM +                  N  +   V+ +              H   +      E +  GISGPEG   SR  E E E ++R + + +   C + +  V +     ++A  KM+G+ +  ET      L+  +Y+  +W  +A+ +T PP+R D +    ++  +    +++V S+H   T   +++GK DF  IPHGV GV++R+S++W+RGV  G ++E  FV+ TS+NAAKI+NLYP +G I  G+ AD+V+W+P  TRTIS  +Q    D N++E + C GVP V I  G V ++   F     +G+   L+     +  KM + E  +     G+ R          ++  + N  K   KD+   D  +NP    RP T  GG R++ +SSFSLSG+QIDD  P R++ R   PPGG+S+ I+
Sbjct:    7 TVRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLNESFMNGTTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKARSHADAKACCDYALHMGVTWWGPKARAQMETLVRDKGVNSFQMYMAYKDMYMLRDSELFQALQNCKDIGAVARVHAENGELVAESSLSHVFIFTHKGAREALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLASAKMQGKVVHGETTTAHAVLNGMQYYHQDWAHAAAFVTVPPLRLDPNTPNYLLSLLGNDTLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSVMWERGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPESTRTISVTTQWQGGDVNLYENLRCHGVPLVTISRGRVVYENGIFTCAEGSGKFYPLRTFPDYLYKKMVQREKCQAL--KGVER-----TPYTGDVAAVQNSGK---KDLGPADGDMNP----RPCTRHGGVRDLHESSFSLSGAQIDDNVPKRASARILAPPGGRSSGIW 576

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: crmp1 (collapsin response mediator protein 1 [Source:ZFIN;Acc:ZDB-GENE-050720-1])

HSP 1 Score: 305.449 bits (781), Expect = 2.310e-95
Identity = 205/575 (35.65%), Postives = 311/575 (54.09%), Query Frame = 1

Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKS-METLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            I +  + ++L+KGG +VN D+   +DV +E+ IIKQ+G++++V G  KVI+    ++IPGGID +T  +   L     D  +  + AALAGGTT II  V  Q G  L+ + +  Q     K  C+Y   V I P+  E VK  +E L ++ GIN FQ+ +  +      ++         KEL  ++ +   +   +   + +++  GI GPEG   SR  E E E ++R + + +   C + I +VM++  A+ VA  + +G  +F E I  +LA     Y+S NW ++A+ +T PP+  D      +   + CGD+ +V S H   + + ++IGK +F  IP G +GVEER+  +WD+ V  G ++E +FV+ TSTNAAKIFNLYP +G IAVGS ADIVIW+P K +TI+A SQ    + NIFEG+ C+G P  V+  G V F+  +  +   TG  I  K        ++K    +      G++R + D       +  +    K I        +K +P   Q PP     RN+  S+FSLSGSQIDD  P RS  R   PPGG+SN+
Sbjct:   12 IPHLTSERLLIKGGRVVNDDQSLYADVYVEDGIIKQVGENLIVPGGVKVIEANGCMVIPGGIDVNTCLHKPYLGTPPVDDFYQGTKAALAGGTTMIIDHVTPQPGDGLLEAFEKWQEAADKKSCCDYSLHVDI-PHWHEGVKEELEQLVQEKGINSFQVYMAYKGLYQMPDSQLYEAFSFLKELGAVVLVHAENGDLIAQEQSKILGMGIIGPEGHPLSRPEELEAEAVFRAITIGNRVNCPVYITKVMSKSAAETVAIARKKGSVVFGEPITASLATDGSHYWSKNWAKAAAYVTSPPLSPDPTTPEHLHSLLACGDLQVVGSGHCAYSTSQKAIGKDNFTLIPEGTNGVEERMGFVWDKAVAMGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPDKIKTITAKSQQSALEYNIFEGMDCRGGPLHVVSQGRVVFEEGKLQVQQGTGRFISRKPFPDFAYQRIKYRNKIMNM--QGVSRGMYDG-----PVYDVPATPKYITP---APSAKTSPTTHQPPPI----RNLHQSNFSLSGSQIDDNIPRRSGHRIVAPPGGRSNI 571

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482])

HSP 1 Score: 306.22 bits (783), Expect = 1.461e-95
Identity = 195/568 (34.33%), Postives = 302/568 (53.17%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKIN-PLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ IE+ +IKQIG++++V G  K ID    L+IPGGID  T   +        D     + AALAGGTT II  V   SG  LV +    +     KV C+Y   + I    +   + +E L +  G+N F + +  +      +A    +    ++L  + ++   +   ++  ++ ++  GI+GPEG   S   E E E  YR + +     C L I +VM+   A ++A+ K +G  ++ ET+  ++      Y+S NW ++A+ +T PPI  D      +   + CGD+ +  S H T T A +++GK +F  IP G +G+EER++++WD+ V SG ++E  FV+ TSTNAAK+FNLYP +G IA GS AD+VIWNP   + ISA + ++  + NIFEG+ C G PEVVI  G +  +  N  +   +G  +  K     V  ++K    L E    G+ R + D          +++     +    T  S+I  P K+Q  P     RN+  S FSLSGSQ DD  P R+T +   PPGG+SN+
Sbjct:   13 RLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCTDAEMYEIFSIIRDLGAIAQVHAENGDIIQEEQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRKGIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLLSCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNVELNIFEGMECHGAPEVVISQGRIVLEDGNLHVSQGSGRFVPRKTFPDYVYKRIKARNRLAEI--RGVPRGLYDG--------PVHDVTITTKSAASTPASRIACPGKIQMGPV----RNLHHSGFSLSGSQEDDHVPRRTTQKIVAPPGGRSNI 566

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482])

HSP 1 Score: 306.605 bits (784), Expect = 1.478e-95
Identity = 197/576 (34.20%), Postives = 306/576 (53.12%), Query Frame = 1

Query:   10 YILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKIN-PLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            YI+ +   ++L+KGG IVN D+ F +D+ IE+ +IKQIG++++V G  K ID    L+IPGGID  T   +        D     + AALAGGTT II  V   SG  LV +    +     KV C+Y   + I    +   + +E L +  G+N F + +  +      +A    +    ++L  + ++   +   ++  ++ ++  GI+GPEG   S   E E E  YR + +     C L I +VM+   A ++A+ K +G  ++ ET+  ++      Y+S NW ++A+ +T PPI  D      +   + CGD+ +  S H T T A +++GK +F  IP G +G+EER++++WD+ V SG ++E  FV+ TSTNAAK+FNLYP +G IA GS AD+VIWNP   + ISA + ++  + NIFEG+ C G PEVVI  G +  +  N  +   +G  +  K     V  ++K    L E    G+ R + D          +++     +    T  S+I  P K+Q  P     RN+  S FSLSGSQ DD  P R+T +   PPGG+SN+
Sbjct:   27 YIVTYD--RLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCTDAEMYEIFSIIRDLGAIAQVHAENGDIIQEEQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRKGIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLLSCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNVELNIFEGMECHGAPEVVISQGRIVLEDGNLHVSQGSGRFVPRKTFPDYVYKRIKARNRLAEI--RGVPRGLYDG--------PVHDVTITTKSAASTPASRIACPGKIQMGPV----RNLHHSGFSLSGSQEDDHVPRRTTQKIVAPPGGRSNI 586

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482])

HSP 1 Score: 305.834 bits (782), Expect = 1.639e-95
Identity = 195/568 (34.33%), Postives = 302/568 (53.17%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKIN-PLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ IE+ +IKQIG++++V G  K ID    L+IPGGID  T   +        D     + AALAGGTT II  V   SG  LV +    +     KV C+Y   + I    +   + +E L +  G+N F + +  +      +A    +    ++L  + ++   +   ++  ++ ++  GI+GPEG   S   E E E  YR + +     C L I +VM+   A ++A+ K +G  ++ ET+  ++      Y+S NW ++A+ +T PPI  D      +   + CGD+ +  S H T T A +++GK +F  IP G +G+EER++++WD+ V SG ++E  FV+ TSTNAAK+FNLYP +G IA GS AD+VIWNP   + ISA + ++  + NIFEG+ C G PEVVI  G +  +  N  +   +G  +  K     V  ++K    L E    G+ R + D          +++     +    T  S+I  P K+Q  P     RN+  S FSLSGSQ DD  P R+T +   PPGG+SN+
Sbjct:    7 RLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCTDAEMYEIFSIIRDLGAIAQVHAENGDIIQEEQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRKGIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLLSCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNVELNIFEGMECHGAPEVVISQGRIVLEDGNLHVSQGSGRFVPRKTFPDYVYKRIKARNRLAEI--RGVPRGLYDG--------PVHDVTITTKSAASTPASRIACPGKIQMGPV----RNLHHSGFSLSGSQEDDHVPRRTTQKIVAPPGGRSNI 560

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482])

HSP 1 Score: 306.22 bits (783), Expect = 2.533e-95
Identity = 196/576 (34.03%), Postives = 306/576 (53.12%), Query Frame = 1

Query:   10 YILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKIN-PLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++  +K  ++L+KGG IVN D+ F +D+ IE+ +IKQIG++++V G  K ID    L+IPGGID  T   +        D     + AALAGGTT II  V   SG  LV +    +     KV C+Y   + I    +   + +E L +  G+N F + +  +      +A    +    ++L  + ++   +   ++  ++ ++  GI+GPEG   S   E E E  YR + +     C L I +VM+   A ++A+ K +G  ++ ET+  ++      Y+S NW ++A+ +T PPI  D      +   + CGD+ +  S H T T A +++GK +F  IP G +G+EER++++WD+ V SG ++E  FV+ TSTNAAK+FNLYP +G IA GS AD+VIWNP   + ISA + ++  + NIFEG+ C G PEVVI  G +  +  N  +   +G  +  K     V  ++K    L E    G+ R + D          +++     +    T  S+I  P K+Q  P     RN+  S FSLSGSQ DD  P R+T +   PPGG+SN+
Sbjct:   30 WVCTYKDDRLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCTDAEMYEIFSIIRDLGAIAQVHAENGDIIQE-QKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRKGIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLLSCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNVELNIFEGMECHGAPEVVISQGRIVLEDGNLHVSQGSGRFVPRKTFPDYVYKRIKARNRLAEI--RGVPRGLYDG--------PVHDVTITTKSAASTPASRIACPGKIQMGPV----RNLHHSGFSLSGSQEDDHVPRRTTQKIVAPPGGRSNI 590

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: bco2 (beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-GENE-5747659])

HSP 1 Score: 303.908 bits (777), Expect = 2.019e-94
Identity = 201/577 (34.84%), Postives = 310/577 (53.73%), Query Frame = 1

Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPN---HRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNAT---GERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
             L F++ ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+   +++IPGGID  T F    N     D     + AALAGGTT II  V  + G+ L+++    +    +K  C+Y   V I        + ME L +  G+N F + +  +      ++    V    +++  + ++   +   +   +  ++  GI+GPEG   SR  E E E   R + + +   C L + +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WDR V SG ++E +FV+ TSTNAAKIFNLYP +G IAVGS AD+VIW+P   RTISA + +   + NIFEG+ C+G P VVI  G  K  L E   +AT   G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K    P     RN+  S FSLSG+Q+DD  P R+T R   PPGG++N+
Sbjct:   40 FLIFQSDRLLIKGGKIVNDDQSFHADIYMEDGLIKQIGENLIVPGGVKTIEAHGRMVIPGGIDVHTCFQKPCNGMVSSDDFFQGTKAALAGGTTMIIDHVVPEPGSSLLSAFDQWREWADTKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAYKDQYQLTDSQIYEVFSVIRDIGAIAEVHAENGDVIAEEQLRILEQGINGPEGHVLSRPEEVEAEAANRSITIANQTNCPLYVTKVMSKSSAEVIAQARKKGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPSTPDFLNSLLSCGDLQVCGSSHCTFNTAQKAVGKDNFTLIPEGTNGAEERMSVVWDRAVVSGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWDPDSVRTISAKTHNSNVEYNIFEGMECRGSPLVVISQG--KIVLEEGTLHATEGSGRYIPRKPFPDYVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKAVTPASSAKTSPAKQPAQPI----RNLHQSGFSLSGAQVDDNIPRRTTQRIVAPPGGRANI 599

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BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl2 (dihydropyrimidinase-like 2 [Source:MGI Symbol;Acc:MGI:1349763])

HSP 1 Score: 307.375 bits (786), Expect = 3.793e-96
Identity = 194/569 (34.09%), Postives = 310/569 (54.48%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+  ++++IPGGID  T F + P+      D     + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + ME L +  G+N F + +  +      ++    VL   +++  + ++   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L + +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAK+FNLYP +G I+VGS AD+VIW+P   +TISA + +   + NIFEG+ C+G P VVI  G +  +     +   +G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K Q PP     RN+  S FSLSG+QIDD  P R+T R   PPGG++N+
Sbjct:   16 RLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQM-PDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTVTPASSAKTSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANI 568

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BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl4 (dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:MGI:1349764])

HSP 1 Score: 306.99 bits (785), Expect = 5.326e-96
Identity = 197/567 (34.74%), Postives = 298/567 (52.56%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K ID    +++PGG+D  T   +        D     + AALAGGTT I+  V   +G  L+ + +  +    S   C+Y   V I    +   + +E L R  G+N F + +  +      +     +    ++L  + ++   +   +E  ++ L+  GI+GPEG   S   E E E +YR + +     C L + +VM++  A +VA+ K  G  +F E I  +L      Y+S NW ++A+ +T PPI  D   A  +   +  GD+ +  S H T T A +++GK +F  IP GV+G+EER+S++W++ V SG ++E EFV+ TSTNAAKIFN YP +G +AVGS AD+VIWNP  T+ ISA S +L  + NIFEG+ C+GVP VVI  G V  +  N  +    G  I  K     V  ++K    L E    G+ R + D  G   E+     P    Q             K+  PP     RN+  S FSLSGSQ DD    R+  +   PPGG+SN+
Sbjct:   16 RLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYD--GPVHEVMLPAKPGSGTQARASCSG------KISVPPV----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNI 568

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Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K ID    +++PGG+D  T   +        D     + AALAGGTT I+  V   +G  L+ + +  +    S   C+Y   V I    +   + +E L R  G+N F + +  +      +     +    ++L  + ++   +   +E  ++ L+  GI+GPEG   S   E E E +YR + +     C L + +VM++  A +VA+ K  G  +F E I  +L      Y+S NW ++A+ +T PPI  D   A  +   +  GD+ +  S H T T A +++GK +F  IP GV+G+EER+S++W++ V SG ++E EFV+ TSTNAAKIFN YP +G +AVGS AD+VIWNP  T+ ISA S +L  + NIFEG+ C+GVP VVI  G V  +  N  +    G  I  K     V  ++K    L E    G+ R + D  G   E+     P    Q             K+  PP     RN+  S FSLSGSQ DD    R+  +   PPGG+SN+
Sbjct:   16 RLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYD--GPVHEVMLPAKPGSGTQARASCSG------KISVPPV----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNI 568

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BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl4 (dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:MGI:1349764])

HSP 1 Score: 306.99 bits (785), Expect = 1.033e-95
Identity = 197/567 (34.74%), Postives = 298/567 (52.56%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K ID    +++PGG+D  T   +        D     + AALAGGTT I+  V   +G  L+ + +  +    S   C+Y   V I    +   + +E L R  G+N F + +  +      +     +    ++L  + ++   +   +E  ++ L+  GI+GPEG   S   E E E +YR + +     C L + +VM++  A +VA+ K  G  +F E I  +L      Y+S NW ++A+ +T PPI  D   A  +   +  GD+ +  S H T T A +++GK +F  IP GV+G+EER+S++W++ V SG ++E EFV+ TSTNAAKIFN YP +G +AVGS AD+VIWNP  T+ ISA S +L  + NIFEG+ C+GVP VVI  G V  +  N  +    G  I  K     V  ++K    L E    G+ R + D  G   E+     P    Q             K+  PP     RN+  S FSLSGSQ DD    R+  +   PPGG+SN+
Sbjct:   37 RLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYD--GPVHEVMLPAKPGSGTQARASCSG------KISVPPV----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNI 589

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BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl4 (dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:MGI:1349764])

HSP 1 Score: 306.99 bits (785), Expect = 1.033e-95
Identity = 197/567 (34.74%), Postives = 298/567 (52.56%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K ID    +++PGG+D  T   +        D     + AALAGGTT I+  V   +G  L+ + +  +    S   C+Y   V I    +   + +E L R  G+N F + +  +      +     +    ++L  + ++   +   +E  ++ L+  GI+GPEG   S   E E E +YR + +     C L + +VM++  A +VA+ K  G  +F E I  +L      Y+S NW ++A+ +T PPI  D   A  +   +  GD+ +  S H T T A +++GK +F  IP GV+G+EER+S++W++ V SG ++E EFV+ TSTNAAKIFN YP +G +AVGS AD+VIWNP  T+ ISA S +L  + NIFEG+ C+GVP VVI  G V  +  N  +    G  I  K     V  ++K    L E    G+ R + D  G   E+     P    Q             K+  PP     RN+  S FSLSGSQ DD    R+  +   PPGG+SN+
Sbjct:   37 RLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYD--GPVHEVMLPAKPGSGTQARASCSG------KISVPPV----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNI 589

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BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q90635|DPYL2_CHICK (Dihydropyrimidinase-related protein 2 OS=Gallus gallus OX=9031 GN=DPYSL2 PE=2 SV=1)

HSP 1 Score: 313.153 bits (801), Expect = 1.574e-97
Identity = 197/568 (34.68%), Postives = 308/568 (54.23%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSP---NHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+   +++IPGGID  T F +        D     + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + ME L +  G+N F + +  +      ++    VL   +++    ++   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAKIFNLYP +G IAVGS AD+VIW+P   +TISA + ++  + NIFEG+ C+G P VVI  G +  +  N  +   +G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K Q PP     RN+  S FSLSG+QIDD  P R+T R   PPGG++N+
Sbjct:   16 RLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHGRMVIPGGIDVHTRFQMPEQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLTAFDQWREWADSKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAFKDRFQLSDSQIYEVLSVIRDIGATAQVHAENGDIIAEEQQRILELGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSIIWDKAVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNISLEYNIFEGMECRGSPLVVISQGKIVLEDGNLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTVTPASSAKTSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANI 568

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BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q9BPU6|DPYL5_HUMAN (Dihydropyrimidinase-related protein 5 OS=Homo sapiens OX=9606 GN=DPYSL5 PE=1 SV=1)

HSP 1 Score: 309.301 bits (791), Expect = 3.595e-96
Identity = 200/579 (34.54%), Postives = 319/579 (55.09%), Query Frame = 1

Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAI-IRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKM-KRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVT--VDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            + N  ++++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL+IPGGID ST+F+   ++    D  ++ + AAL GGTT II  V       LV++ +  +     KV C+Y   V I     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GI+GPEG   SR  E E E  +R++ + +   C + +  V +     ++A  KM+G+ + +ET      L+   Y+  +W  +A+ +T PP+R D + +  + S+   D +++VAS+H   T   +++GK DF  IPHGVSGV++R+S++W+RGV  G ++E  FV+ TS+NAAK+ NLYP +G I  G+ AD+V+W+P  T+TISA +Q    D N++E + C GVP V I  G V ++   F+    TG+   L+     V  K+ +R + L+  G         D      ++  + +P K   K++ T   D+   P+        GG R++ +SSFSLSGSQIDD  P R++ R   PPGG+S+ I+
Sbjct:    2 LANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRG--------VDRTPYLGDVAVVVHPGK---KEMGTPLADTPTRPVTRH-----GGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564

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BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|O02675|DPYL2_BOVIN (Dihydropyrimidinase-related protein 2 OS=Bos taurus OX=9913 GN=DPYSL2 PE=1 SV=1)

HSP 1 Score: 309.686 bits (792), Expect = 3.686e-96
Identity = 196/569 (34.45%), Postives = 310/569 (54.48%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+  ++++IPGGID  T F + P+      D     + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + ME L +  G+N F + +  +      ++    VL   +++  + ++   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAK+FNLYP +G IAVGS AD+VIW+P   +TISA + +   + NIFEG+ C+G P VVI  G +  +     +   +G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K Q PP     RN+  S FSLSG+QIDD  P R+T R   PPGG++N+
Sbjct:   16 RLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQM-PDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYITKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTVTPASSAKTSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANI 568

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BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q62951|DPYL4_RAT (Dihydropyrimidinase-related protein 4 (Fragment) OS=Rattus norvegicus OX=10116 GN=Dpysl4 PE=1 SV=1)

HSP 1 Score: 308.916 bits (790), Expect = 4.789e-96
Identity = 198/567 (34.92%), Postives = 299/567 (52.73%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K ID    +++PGG+D  T      L     D     + AALAGGTT I+  V   +G  L+ + +  +    S   C+Y   V I    +   + +E L R  G+N F + +  +      +     +    ++L  + ++   +   +E  ++ L+  GI+GPEG   S   E E E +YR + +     C L I +VM++  A +VA+ K  G  +F E I  +L      Y+S NW ++A+ +T PPI  D   A  +   +  GD+ +  S H T T A +++GK +F  IP G++G+EER+S++W++ V SG ++E EFV+ TSTNAAKIFN YP +G +AVGS AD+VIWNP  T+ ISA S +L  + NIFEG+ C+G+P VVI  G V  +  N  +    G  I  K     V  ++K    L E    G+ R + D  G   E+     P    Q           P K+  PP     RN+  S FSLSGSQ DD    R+  +   PPGG+SN+
Sbjct:    8 RLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYITKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGINGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGMPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYD--GPVHEVMLPAKPGSGTQARASC------PGKISVPPV----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNI 560

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BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q9JHU0|DPYL5_RAT (Dihydropyrimidinase-related protein 5 OS=Rattus norvegicus OX=10116 GN=Dpysl5 PE=1 SV=1)

HSP 1 Score: 308.531 bits (789), Expect = 7.401e-96
Identity = 201/579 (34.72%), Postives = 319/579 (55.09%), Query Frame = 1

Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA-IIRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKM-KRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVT--VDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            + N  ++++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL+IPGGID ST+F+   ++    D  ++ + AAL GGTT II  V       LV + +  ++    KV C+Y   V I     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GI+GPEG   S   E E E  +R++ + +   C + +  V +     ++A  KM+G+ + +ET      L+   Y+  +W  +A+ +T PP+R D + +  + S+   D +++VAS+H   T   +++GK DF  IPHGVSGV++R+S++W+RGV  G ++E  FV+ TS+NAAKI NLYP +G I  G+ AD+V+W+P  T+TISA +Q    D N++E + C GVP V I  G V ++   F+    TG+   L+    +V  K+ +R + L+  G         D      ++  + NP K   K++ T   D+   P+        GG R++ +SSFSLSGSQIDD  P R++ R   PPGG+S+ I+
Sbjct:    2 LANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVFHACRDFGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKTLKVRG--------VDRTPYLGDVAVVVNPGK---KEMGTPLADTPTRPVTRH-----GGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564

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BLAST of Dihydropyrimidinase vs. TrEMBL
Match: K1PGY5 (Dihydropyrimidinase OS=Crassostrea gigas OX=29159 GN=CGI_10005185 PE=4 SV=1)

HSP 1 Score: 345.51 bits (885), Expect = 1.497e-106
Identity = 213/571 (37.30%), Postives = 324/571 (56.74%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVE-EELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQD--AAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKV--IQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            ++L+KGG IVN D+ F +D+ IE+ IIKQ+G ++V+ G  + I+   KL++PGGID  T+  L        D  ++ + AALAGGTT II  V +Q G  L+ +    +     KV C+YG  V +    D+  K METL  + GIN F+M +  +    +N + +    K  +    L +   ++ +L A + +E++  GISGPEG    R  E E E   R + + +   C L I  VM++  A +V+K + EG+ +F E I  +L      Y++  W  +A  +  PP+R D      ++  +   D+ +  +++ T +   +++GK DFR IP+GV+GVE+R+S++W++GV SG ++ C FV+ TSTNAAKIFN+YP +G IAVGS ADIVIW+P ++RTISA + H   D NIFEG+ C GVP  VI NG V     +  +    G  I    N ++V  ++ +    RE  +M    E     G    +  I N  +V  +++D   +          RPPT GG RN+QDSSF+LSG Q DD+ P R+ IRT++PPGGKS+ ++
Sbjct:   84 RLLIKGGKIVNDDQSFDADIYIEDGIIKQVGTNLVIPGGARTIEARGKLVMPGGIDTHTHMQLPFMGTYAVDDFYSGTKAALAGGTTMIIDFVLDQKGVSLLEAYDKWRGWADPKVCCDYGLHVGVTWWSDQVAKEMETLCAEKGINSFKMFLAYKDVFMLNDDELYESFKRIKELGALGMVHAENGHLIAEKSKEMLKMGISGPEGHEMCRPEEVEAEATQRAITIANQANCPLYIVHVMSKSSADVVSKARREGKVVFGEPIAASLGTDGTHYWNKCWRHAAGHVMGPPLRPDSSTPGYLMDLLANNDLQVTGTDNCTFSADQKALGKDDFRKIPNGVNGVEDRMSVIWEKGVHSGKMDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWDPKESRTISAKTHHQAVDFNIFEGMVCHGVPVYVITNGHVVLDEGQLKVTQGMGRFIPTPCNAEMVYGRVAK----RELARMPQKVERDPYTG---PVVKIENQDEVPGVKRDENPIVGDTASFAHSRPPTRGGGRNLQDSSFALSGEQFDDKAPRRAQIRTSNPPGGKSSGLW 647

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BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A1W7RAR0 (Dihydropyrimidinase OS=Hadrurus spadix OX=141984 PE=4 SV=1)

HSP 1 Score: 340.502 bits (872), Expect = 1.795e-105
Identity = 205/581 (35.28%), Postives = 323/581 (55.59%), Query Frame = 1

Query:   16 LNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRND--QDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERI------DLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            L     ++L+KGG +VN D  F +DV +E+ IIKQ+G+ +++ G T+ I+   K ++PGGIDP T+F    LS    D  +N + AALAGGTT I+  V +     L+ + +  +S    KV C+Y   + I    D   + M+ L ++ GIN F   +  +      +   + V     +L  L ++   +   +  +EE ++  GI+GPEG+  +R  E E E   R + L +   C L +  VM++  A ++++ + EG  ++ E I  ALA     YF+  W  +A+ +  PP+R D    + ++  ++CGD+ + AS ++T   + +++G  DF  IP GV+GVE+R+S++W+RGV SG I+ C FV+ TSTNAAKIFN+YP +G I VGS ADIV+W+P +TRTIS+ + H   D NIFE ++C GVPE VI  G V  +  E  +    G  I          NC + ++K ++         + + RE      V  E+  + +  +V  ++ V +          RPPT  G RN+QDS+FSLSG+QIDD K  R+ I+ N+PPGG+S  ++
Sbjct:   12 LQSAQTRLLIKGGKVVNDDLIFDADVYVEDGIIKQVGRDLIIPGGTRTIEAKGKFVMPGGIDPHTHFEFPFLSVKSADDFYNGTKAALAGGTTMIMDFVVDPD-CSLLEAYEKWRSVADEKVCCDYNLHIGITSWSDNIEQEMDILTKEKGINSFMTFMAYKDVLMLRDDELLKVFDISSKLGALAQVHAENGDIIHELEERILALGITGPEGYVYTRPEEIEAEATQRAITLANQMNCPLYVVHVMSKSAADVISRKRKEGCIVYGEAIAAALATDGTHYFNQCWGHAAAHVMSPPLRPDPRTPSYLMDYLNCGDLAVTASANSTFNTSQKALGAEDFTKIPPGVNGVEDRMSVIWERGVVSGKIDPCRFVAVTSTNAAKIFNIYPRKGRIQVGSDADIVVWDPYRTRTISSKTHHHSVDFNIFEDMTCHGVPEYVIAQGRVVLEEGELHVCQGMGRFIPASPFSPFVFNCIMEREKARQ--------PIKVNREAYTG-PVKEEVAYLTDGTQVPYRETVIMSQSSKEFH-SRPPTRSGGRNLQDSTFSLSGAQIDDNKSPRAGIKINNPPGGRSTGLW 581

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BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A267FG46 (Amidohydro-rel domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032114g1 PE=4 SV=1)

HSP 1 Score: 334.724 bits (857), Expect = 5.373e-103
Identity = 201/571 (35.20%), Postives = 312/571 (54.64%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQ--MTIGNEI---NANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRN-DQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLK------MQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSN 1698
            ++L+KGG +VN D   ++DV +E  +IKQ+G  ++  G  +VID    LI+PGGIDP T+  +     +  D  +  + AALAGGTT II  V    G  L++     ++    KV C+YG  V +    D+    M TL ++ GIN F+  M   N     +   ++V + C++L  + ++   +   +E   E+L+  GI GPEG   SR    E+E   R L +     C L +  VM+ +  + ++K +  G+  + E I   LA  +  Y    W  +A  +  PP+R+      + R +  G++    ++H       +++GK DFR IP+GV+GVE+R+S+LW++GV++GI++ C+FV+ATSTNAAK+FNLYP +G IAVGS ADIV+WN  +TRTISA + H   D NIFEG+ C G+ E VI  G +     +  +    G  + +      V +++++ E  +  G + + R+  D  G   +++      K + K+           +        RPPT GG R+MQ+SSFSLSG+Q DD KP RS IRT+ PPGG S+
Sbjct:   23 RLLIKGGKVVNDDGIQEADVYVEGGVIKQVGTGLLTPGGVRVIDAAGMLIMPGGIDPHTHMQMPFMGTHSADDFYTGTRAALAGGTTMIIDFVACPRGDSLMDWYNKYRAWADEKVCCDYGLHVIVPQWGDKTANEMATLVKEKGINSFKCFMAYRNVFLLEDDEMLNVFQACRKLGAVAQVHAENGKIIERKAEQLVADGIRGPEGHSYSRPEAMEIEATTRALAIADEANCPLYVVHVMSAEAGEAISKARRRGQVCYGEPIAAGLACDNSSYQHTCWRHAAGHVLSPPLRDPSTKERLWRMLATGELTCTGTDHCVFKADQKALGKDDFRRIPNGVNGVEDRMSVLWEKGVETGILDPCQFVAATSTNAAKVFNLYPQKGRIAVGSDADIVVWNAKETRTISAKTHHQNVDFNIFEGMVCHGIAEFVISGGRLVVDERQLKVTQGAGRFVPMPAFPPYVYNRLEKREAAKSAGTVAVARDAYD--GPVIDLKAEQERQKAVAKEQPGAAGGGGGPEAAAENVFHRPPTRGGGRHMQESSFSLSGAQFDDTKPARSGIRTHQPPGGASS 591

[Close]

BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A183TGQ2 (Dihydropyrimidinase OS=Schistocephalus solidus OX=70667 PE=4 SV=1)

HSP 1 Score: 333.569 bits (854), Expect = 9.600e-103
Identity = 206/574 (35.89%), Postives = 318/574 (55.40%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTI---GNEINANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITRE-----ISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            ++ LKGG +VN DRKF +D+ IE+ +IKQ+G ++ + G  + +DV  KL++PGGID  T+  +     +  D  ++ + AALAGGTT II  V    G+ ++ + +  +    SKV C+Y   V +   +++    ME L ++ GIN F+  +   G  +  +       C+  +     +VH  +   +   +EE+I  GI GPEG   SR    E+E   R + L     C L +  VM+   A  +A+ + +G  +  E +   L      Y    W  +A  +  PP+R + +    +++++  G ++   ++H       +++GK DFR IP+GV+GVE+R+S++W++GV SGII+ C+FV+ TSTNAAKIFN+YP +G I VGS ADIV+W+P   RTISA + H   D NIFEG+ C GVP +VI NG V  + ++  +   TG  +        V  K++  + LRE  ++ + RE     ++D +G A +   I       + D      +      QRPPTS G RNMQDSSF+LSGSQ+DD  P+RSTIRT  PPGG S  ++
Sbjct:   25 RLHLKGGTVVNDDRKFVADIYIEDGVIKQVGTNLSIPGGVRTVDVRGKLVMPGGIDTHTHMEMPFMGTHSSDDFYSGTKAALAGGTTMIIDFVCPARGSSILEAYEQYREKADSKVCCDYALHVIVPHFDEKLSNEMEVLTKEKGINSFKSFLAYPGVFMLEDDELYDFFCRCRELGALAQVHAENGKLISRKQEEVIQHGILGPEGHPFSRPEAAEVEATSRAITLADTANCPLYVVHVMSALAANKIAEARQDGILVIGEAVAAGLGTDGSHYLDKCWRSAAGYVMSPPLRMNPETPRLLMKALANGHLECTGTDHCVFKADQKALGKDDFRKIPNGVNGVEDRMSVIWEKGVVSGIIDPCKFVAITSTNAAKIFNIYPRKGRIEVGSDADIVVWDPEAERTISASTHHQNVDFNIFEGMRCHGVPLIVITNGHVVLEDDDLKVSQGTGRFVPTPPFSPYVYAKIEGRQKLRE--RIPVAREPYTGPVAD-LGAALQATDIKTVFANGKGD------QAQAFNRQRPPTSAGGRNMQDSSFALSGSQVDDALPVRSTIRTQQPPGGASRSLW 589

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BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A3P7D5Z0 (Amidohydro-rel domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS15650 PE=4 SV=1)

HSP 1 Score: 333.569 bits (854), Expect = 9.911e-103
Identity = 206/574 (35.89%), Postives = 318/574 (55.40%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTI---GNEINANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITRE-----ISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            ++ LKGG +VN DRKF +D+ IE+ +IKQ+G ++ + G  + +DV  KL++PGGID  T+  +     +  D  ++ + AALAGGTT II  V    G+ ++ + +  +    SKV C+Y   V +   +++    ME L ++ GIN F+  +   G  +  +       C+  +     +VH  +   +   +EE+I  GI GPEG   SR    E+E   R + L     C L +  VM+   A  +A+ + +G  +  E +   L      Y    W  +A  +  PP+R + +    +++++  G ++   ++H       +++GK DFR IP+GV+GVE+R+S++W++GV SGII+ C+FV+ TSTNAAKIFN+YP +G I VGS ADIV+W+P   RTISA + H   D NIFEG+ C GVP +VI NG V  + ++  +   TG  +        V  K++  + LRE  ++ + RE     ++D +G A +   I       + D      +      QRPPTS G RNMQDSSF+LSGSQ+DD  P+RSTIRT  PPGG S  ++
Sbjct:   25 RLHLKGGTVVNDDRKFVADIYIEDGVIKQVGTNLSIPGGVRTVDVRGKLVMPGGIDTHTHMEMPFMGTHSSDDFYSGTKAALAGGTTMIIDFVCPARGSSILEAYEQYREKADSKVCCDYALHVIVPHFDEKLSNEMEVLTKEKGINSFKSFLAYPGVFMLEDDELYDFFCRCRELGALAQVHAENGKLISRKQEEVIQHGILGPEGHPFSRPEAAEVEATSRAITLADTANCPLYVVHVMSALAANKIAEARQDGILVIGEAVAAGLGTDGSHYLDKCWRSAAGYVMSPPLRMNPETPRLLMKALANGHLECTGTDHCVFKADQKALGKDDFRKIPNGVNGVEDRMSVIWEKGVVSGIIDPCKFVAITSTNAAKIFNIYPRKGRIEVGSDADIVVWDPEAERTISASTHHQNVDFNIFEGMRCHGVPLIVITNGHVVLEDDDLKVSQGTGRFVPTPPFSPYVYAKIEGRQKLRE--RIPVAREPYTGPVAD-LGAALQATDIKTVFANGKGD------QAQAFNRQRPPTSAGGRNMQDSSFALSGSQVDDALPVRSTIRTQQPPGGASRSLW 589

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BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:103040013])

HSP 1 Score: 303.523 bits (776), Expect = 9.858e-95
Identity = 191/575 (33.22%), Postives = 305/575 (53.04%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNF-----NLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIG-----NEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIG-NATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGN------RNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            K+++KGG IVN D+ F +D+ IE+  IKQIG++++V    K +D    ++IPGGID +T+       +SP   D  ++ + AALAGGTT II  V  + GA L+ +    +     +  C+Y   + I    +   + +ETL +  G+N F + +         ++    +    ++L  + ++   +   ++  ++ L+  GI+GPEG   S   E E E +YR + +     C L I +VM+   A ++AK + +G  I+ E I  +L      Y+S NW ++A+ +  PP+  D      +   + CGD+ + AS H T + A +++GK +F  IP G +G+EER+S++WD+ V SG ++E EFV+ TSTNAAKIFNLYP +G IAVGS AD+VIWN  +T+T SA S +L  + NIFE + C+G P VVI  G +  +  +      +G  +  K     V  ++K    + E    G+ R   D                    D++++   + P    R P+S G       RN+  S F+LSG+Q+DD  P R+  R   PPGG+SN+
Sbjct:   16 KLIIKGGKIVNDDQSFYADIFIEDGTIKQIGENLIVPSGVKTVDAYGHIVIPGGIDVNTSLQAQHMGMSPA--DDFYHGTRAALAGGTTMIIDHVVPEPGASLLAAFDQWRDVADKRSCCDYSLHIDITRWHEGMFEELETLVKDQGVNSFLVFMSYKDRFQSSDSQMYEIFGILRDLGAIAQVHAENGDIIDEEQKRLLDMGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSRPAADVIAKARKKGMVIYGEPIAASLGTDGSHYWSQNWAKAAAFVMSPPLSPDPATPDYLNSMLSCGDLQVTASAHCTFSTAQKAVGKDNFTLIPEGTNGIEERMSIVWDKAVASGKMDENEFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWNTKETKTFSATSHNLTVEMNIFEDMECRGFPVVVISQGRIVLEDGKLDAMEGSGRFVPRKAFPDYVYKRIKARSRMAE--ARGVPRGNYDG----------------PVHDVISMTKSVPPTPTTRGPSSSGKNTPGPARNLHQSGFTLSGTQMDDHIPRRTAQRIVAPPGGRSNI 570

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BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:103040013])

HSP 1 Score: 303.138 bits (775), Expect = 1.636e-93
Identity = 191/575 (33.22%), Postives = 305/575 (53.04%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN-----LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIG-----NEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIG-NATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGN------RNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            K+++KGG IVN D+ F +D+ IE+  IKQIG++++V    K +D    ++IPGGID +T+       +SP   D  ++ + AALAGGTT II  V  + GA L+ +    +     +  C+Y   + I    +   + +ETL +  G+N F + +         ++    +    ++L  + ++   +   ++  ++ L+  GI+GPEG   S   E E E +YR + +     C L I +VM+   A ++AK + +G  I+ E I  +L      Y+S NW ++A+ +  PP+  D      +   + CGD+ + AS H T + A +++GK +F  IP G +G+EER+S++WD+ V SG ++E EFV+ TSTNAAKIFNLYP +G IAVGS AD+VIWN  +T+T SA S +L  + NIFE + C+G P VVI  G +  +  +      +G  +  K     V  ++K    + E    G+ R   D                    D++++   + P    R P+S G       RN+  S F+LSG+Q+DD  P R+  R   PPGG+SN+
Sbjct:  119 KLIIKGGKIVNDDQSFYADIFIEDGTIKQIGENLIVPSGVKTVDAYGHIVIPGGIDVNTSLQAQHMGMSPA--DDFYHGTRAALAGGTTMIIDHVVPEPGASLLAAFDQWRDVADKRSCCDYSLHIDITRWHEGMFEELETLVKDQGVNSFLVFMSYKDRFQSSDSQMYEIFGILRDLGAIAQVHAENGDIIDEEQKRLLDMGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSRPAADVIAKARKKGMVIYGEPIAASLGTDGSHYWSQNWAKAAAFVMSPPLSPDPATPDYLNSMLSCGDLQVTASAHCTFSTAQKAVGKDNFTLIPEGTNGIEERMSIVWDKAVASGKMDENEFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWNTKETKTFSATSHNLTVEMNIFEDMECRGFPVVVISQGRIVLEDGKLDAMEGSGRFVPRKAFPDYVYKRIKARSRMAE--ARGVPRGNYDG----------------PVHDVISMTKSVPPTPTTRGPSSSGKNTPGPARNLHQSGFTLSGTQMDDHIPRRTAQRIVAPPGGRSNI 673

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BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl5a (dihydropyrimidinase like 5 [Source:NCBI gene;Acc:103037842])

HSP 1 Score: 297.745 bits (761), Expect = 1.076e-92
Identity = 193/571 (33.80%), Postives = 312/571 (54.64%), Query Frame = 1

Query:   31 MKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPT-SGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            +++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL++PGGID S +     ++    D  ++ + AALAGGTT +I  V  +    L+++ +  +S   +K  C+Y   V +     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GISGPEG   SR  E E E ++R + + +   C + +  V +     ++A  KM+G+ +  ET      ++  +Y+  +W  +A+ +T PP+R D +    ++  +    +++V S+H   T   +++GK DF  IPHGV GV++R+S++W++GV  G ++E  FV+ TS+NAAKI+NLYP +G I  G+ AD+V+W+P  TRTIS  +Q    D N++EG+ C GVP V I  G V ++   F     +G+   L+     +  KM + E  +     G+ R  +  IG   ++  + N  K   K+ V     +     QRP T  GG R++ +SSFSLSG QIDD  P RS+ R   PPGG+S+ I+
Sbjct:    8 VRILIKGGKVVNDDYTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLQETFMNATTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKCRSHADAKSCCDYALHVAVTWWGPKVRAQMETLVREKGVNSFQMFMAYKDVYMLRDSELFQALQNCKDIGAIARVHAENGELVAEGAKEALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLATAKMQGKVVHGETSTAHAVINGLQYYHQDWAHAAAYVTVPPLRLDPNTPNFLLSLLGNDSLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSIIWEKGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPDATRTISVTTQWQGGDVNLYEGLRCHGVPLVTISRGRVVYENGIFTCAEGSGKFYPLRTFPDYLYKKMVQREKCQAL--KGVDR--APYIG---DVAAVQNSGK---KETVPAVGDL----AQRPCTRHGGMRDLHESSFSLSGVQIDDNLPKRSSQRILAPPGGRSSGIW 564

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BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl2b (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:103036518])

HSP 1 Score: 297.36 bits (760), Expect = 2.291e-92
Identity = 193/569 (33.92%), Postives = 304/569 (53.43%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KG  IVN D+ F +D+ +E+ +IKQIG++++V G  K ID   ++++PGGID  T F + P+      D  +  + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + METL +  G+N F + +  +      ++    V    ++L  + ++   +   +   +  ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  + ++A+ + +G  ++ E I  ++      Y+S NW ++A+ +T PP+  D      +   + CGD+ +V S H T   A R++GK DF  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAKIFNLYP +G IAVGS AD+V+W+P  T+ ISA S +   + NIFEG+  +G P VVI  G +  +         +G  +  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K    P     RN+  S FSLSG+Q+DD  P R+T R   PPGG++N+
Sbjct:   17 RLLIKGAKIVNDDQSFSADIYMEDGLIKQIGENLIVPGGVKTIDAHGQMVMPGGIDVHTRFQM-PDRGMTAADDFYQGTRAALAGGTTMIIDHVVAEPGVGLIAAFNQWREWADSKSCCDYSLHVDITEWHKGIQEEMETLVKDHGVNSFLVYLAYKDVFQLTDSQIYEVFSGIRDLGAIAQVHAENGDIIAEEQRRILELGITGPEGHVLSRPEEVEAEAVNRSVTVANQTNCPLYITKVMSKSASDVIAQARKKGTVVYGEPITASVGTDGSHYWSKNWGKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQVVGSGHCTFNTAQRAVGKDDFTLIPEGTNGAEERMSIIWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNSAVEYNIFEGMEVRGAPLVVISQGKIVLEEGTLHTTEGSGRYVPRKPFPDYVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKAVTPASSAKTSPAKQASQPV----RNLHQSGFSLSGAQVDDNIPRRNTQRIVAPPGGRANI 569

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BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl2b (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:103036518])

HSP 1 Score: 297.745 bits (761), Expect = 6.746e-92
Identity = 194/575 (33.74%), Postives = 307/575 (53.39%), Query Frame = 1

Query:   16 LNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            +N  + ++L+KG  IVN D+ F +D+ +E+ +IKQIG++++V G  K ID   ++++PGGID  T F + P+      D  +  + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + METL +  G+N F + +  +      ++    V    ++L  + ++   +   +   +  ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  + ++A+ + +G  ++ E I  ++      Y+S NW ++A+ +T PP+  D      +   + CGD+ +V S H T   A R++GK DF  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAKIFNLYP +G IAVGS AD+V+W+P  T+ ISA S +   + NIFEG+  +G P VVI  G +  +         +G  +  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K    P     RN+  S FSLSG+Q+DD  P R+T R   PPGG++N+
Sbjct:   65 INDTSDRLLIKGAKIVNDDQSFSADIYMEDGLIKQIGENLIVPGGVKTIDAHGQMVMPGGIDVHTRFQM-PDRGMTAADDFYQGTRAALAGGTTMIIDHVVAEPGVGLIAAFNQWREWADSKSCCDYSLHVDITEWHKGIQEEMETLVKDHGVNSFLVYLAYKDVFQLTDSQIYEVFSGIRDLGAIAQVHAENGDIIAEEQRRILELGITGPEGHVLSRPEEVEAEAVNRSVTVANQTNCPLYITKVMSKSASDVIAQARKKGTVVYGEPITASVGTDGSHYWSKNWGKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQVVGSGHCTFNTAQRAVGKDDFTLIPEGTNGAEERMSIIWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNSAVEYNIFEGMEVRGAPLVVISQGKIVLEEGTLHTTEGSGRYVPRKPFPDYVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKAVTPASSAKTSPAKQASQPV----RNLHQSGFSLSGAQVDDNIPRRNTQRIVAPPGGRANI 623

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BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: dpysl3 (dihydropyrimidinase like 3 [Source:NCBI gene;Acc:553166])

HSP 1 Score: 243.817 bits (621), Expect = 6.680e-74
Identity = 151/478 (31.59%), Postives = 245/478 (51.26%), Query Frame = 1

Query:  310 QSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGN-ATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDN----IGVASEIRTINNPHKVIQKDIVTVDSKINPLK--MQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            + G  LV +L A +    +KV C+Y   V +    +   + +E L +  GIN F + +  +      +     V    +++  +  +   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  A ++++ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D      +   + CGD+ +  S H T T A +++GK +F  IP G +G+EER+S++WD+ V +G ++E +FV+ TSTNAAKIF+LYP +G IAVGS AD+VIW P    TISA +     + NIFEG+  +G P VVI  G +  +  +       G  +  K   + V  ++K    L E    G+ R + D     +  +S   T   P         T  ++ +P K   Q  P     RN+  S FSLSG+Q+DDE P R+  R   PPGG+SN+
Sbjct:    8 EPGQGLVAALDAWREWADAKVCCDYSLHVAVPQWHEGVAEELEILVKDRGINSFLVYMAYKDQYQMSDTEMYEVFTFLRDIGAIAMVHAENGDIIAEEQKRILEMGIAGPEGHVLSRAEEVEAEAVNRAISIANHTNCPLYITKVMSKSAADVISQARKKGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNSLLSCGDLQVTGSAHCTFTTAQKALGKDNFTLIPEGTNGIEERMSIVWDKAVATGKMDENQFVAVTSTNAAKIFSLYPRKGRIAVGSDADLVIWEPDTITTISAKTHTAAVEYNIFEGMEVRGAPLVVISQGRIVLEEGKLSATQGAGRFVPRKAFPEQVYKRIKARNKLAEM--RGVPRGLYDGPVFELSSSSVRSTTATP---------TPSARTSPAKSAAQSAPL----RNLHQSGFSLSGAQVDDELPRRTGHRIVAPPGGRSNI 470

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BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006054.1 (pep scaffold:Pmarinus_7.0:GL477305:540:7425:1 gene:ENSPMAG00000005460.1 transcript:ENSPMAT00000006054.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 171.4 bits (433), Expect = 2.944e-49
Identity = 98/263 (37.26%), Postives = 148/263 (56.27%), Query Frame = 1

Query:  925 CGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIG-NATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGN---RNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
             GD+ +  S H T + A +++GK DF  IP G +G+EER+S++WD+GV +G ++E +FV+ TSTNAAK+FNLYP +G IAVGS AD++IW+P   +TISA + H   + NIFEG+  +GVP  VI  G +  +          G  +  K   + V  ++K    L E    G+ R + D  G   E+ T+++     +       +K +P +      +      RN+  S F LSG+Q+DD  P R+  R   PPGG+SN+
Sbjct:    1 SGDLHVTGSAHCTFSTAQKALGKDDFTLIPEGTNGIEERMSIVWDKGVATGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLIIWDPDVVKTISAKTHHQAVEYNIFEGMEVRGVPLAVISQGKIVMEDGTLHAMQGVGRFVPRKAFPEQVYKRIKARSQLTEL--QGVPRGLYD--GPVQEV-TVSS-----RTATPAASAKTSPTRQTAAAAAAQASNLRNLHQSGFCLSGAQVDDNMPRRTGHRIVAPPGGRSNI 253

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BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: dpysl2b (dihydropyrimidinase like 2b [Source:ZFIN;Acc:ZDB-GENE-031105-1])

HSP 1 Score: 99.7525 bits (247), Expect = 8.917e-24
Identity = 76/261 (29.12%), Postives = 134/261 (51.34%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVA--KMKMEGRPI 786
            ++L+KGG I+N D+ F +D+ +E+  IKQIG +++V G  K I+   ++++PGGID  T+     L  +  D  +  + AALAGGTT II  V  + G  L+ + +  +    +K  C+Y   VQ+     E    METL +  G+N F + +  +      +A         ++L  +  +   + + +   ++ ++   I+GPEG   SR  E E E + R + + +   C L I +VM+   A ++A  + K+ G+ I
Sbjct:    2 RLLIKGGRIINDDQSFTADIYVEDGFIKQIGDNLIVPGGVKSIEANGRMVMPGGIDVHTHLQMPYLGTSTMDDFYQGTRAALAGGTTMIIDHVIPEPGCSLLGAYEQWREWADAKACCDYSLHVQLTYWNSELCSEMETLIKDKGVNSFLVYMAYKDKYQLTDAEIYEAFTAIRDLGAIALVHAENGSIIAEEQKRILGLQITGPEGHVLSRPEEVEAEAVNRAITIGNQTNCPLYITKVMSRSAADVIALSRKKVRGQYI 262

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO46551 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPQ7])

HSP 1 Score: 298.901 bits (764), Expect = 1.785e-93
Identity = 204/583 (34.99%), Postives = 310/583 (53.17%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE----IN-ANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGE-------------RIDLK-INCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            ++L+KGG IVN D+ F++DV IEN +IK+I +S++  G TKVID + KLI+PGGID  T+  +        D     + AALAGGTT II  V    G  L+ +    +     KV C+YGF V +    +E  + ME L ++ GIN F+  +  +    IN A  ++  KKCKE+  + ++   +   ++   +++I  GI+GPEG    R  E E E   R + + +   C L +  VM++  AK+++  +  G+ +  E I   L      Y+   W   A  +  PP+R D      ++  +   D+    +++ T ++  +++GK DFR IP+GV+G+E+R+S++W++GV +G ++ C FV+ TST AAKIFN+YP +G IAVGS ADIV+W+P  TR ISA + H   D NIFEG+ C GVP V I  G V ++  EF +   +G              RI  +  NCQ  K   + Y      GK+ +T E      V        +P +   K+   V  K NP           +R++  S F LSG Q DDE+P R + R   PPGG S+++F
Sbjct:   10 RILIKGGTIVNDDQMFEADVYIENGLIKEISKSVICPGGTKVIDASRKLILPGGIDTHTHLQMPFMGTTAIDDFFIGTKAALAGGTTMIIDFVIPAKGESLLEAYDKWRGWADEKVCCDYGFHVAVTWWSEEVAEEMEILVKEKGINSFKTFMAYKDVMMINDAEMINCYKKCKEIGAIAQVHAENGDLIDESAKKMIAMGITGPEGHEMCRPEEVEAEATQRAITIANQVSCPLYVVHVMSKSSAKVISDARRLGKVVIGEPIAAGLGCDGTNYWHKCWRHGAGHVMGPPLRPDTSTPEHLMNLLANDDLQCTGTDNCTFSSEQKALGKNDFRKIPNGVNGIEDRMSVIWEKGVHAGKMDPCRFVAVTSTTAAKIFNVYPQKGRIAVGSDADIVVWDPEATRVISAKTHHQAVDFNIFEGMECHGVPVVTISQGKVVYEGGEFHVVRGSGRFIPTPPFSHYMYSRIHTRDKNCQPKKVDREPYT-----GKV-LTIEPDPKAAV------FTSPAQRRMKEREEV--KKNP-----------HRDLHRSGFELSGRQFDDERPYRPSSRVAKPPGGASSIVF 567

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO49158 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH45])

HSP 1 Score: 60.4622 bits (145), Expect = 9.912e-10
Identity = 46/180 (25.56%), Postives = 80/180 (44.44%), Query Frame = 1

Query:  805 PALALSSHKYFSNNWDESASLITD----PPIRNDQDAAII-RSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLN 1329
            P    ++H Y S   +E     T     PPIR+  +  ++  ++   DID+V S+H+  T   + + + DF     G+S ++  LS+ W  G +   +   + V       +K+ +L   +G I+VG  AD VIW+P +   + +     +N    + G    G     I+ G V F  N
Sbjct:  201 PLTVETTHHYLSLTAEEVPDGATQYKCCPPIRDRSNQEVLWNAVKFRDIDLVVSDHSPCTPDLKLLDQGDFIGAWGGISSLQYGLSLFWS-GARCRGLGLHDVVRVLCEQPSKLCSLQHRKGMISVGKDADFVIWDPNEEFMVKSSDIRHRNKVTPYAGKKLFGRVHQTILRGQVVFSGN 379

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl4 (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:101156240])

HSP 1 Score: 309.301 bits (791), Expect = 4.772e-97
Identity = 194/575 (33.74%), Postives = 312/575 (54.26%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN-----LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKF---QLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQR----PPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++++KGG IVN D+ F +DV +E+  IKQIG++++V    K +D   +L+IPGGID +TN +     +SP   D  +  + AAL+GGTTTI+  V  + G+ L+     ++   +    C++   + I    D   + +ETL +  G+N F   +  +    ++++                +VH  +   ++  + ++++ GI+GPEG   S   E E E +YR + +     C L I +VM++  A ++AK + +G  ++ E I  +LA     Y+S +W  +A+L+  PP+  D      +   + CGD+ + +S   + + A +++GK DF  IP G +G+EER++++WDR V SG ++E EFV+ TSTNAAK+FN+YP +G IAVGS ADIV+WNP +TRT+SA + +L  + NI EG+  +GVP VVI  G V     QLN  +   +G  +  K     V      Y+ ++   KM  TR +           + + P      D+ ++   + P    R    P T  G RN+  S F+L+GSQIDD  P RS  R   PPGG+SN+
Sbjct:   16 RLIIKGGKIVNDDQSFYADVFVEDGTIKQIGENLIVPPGVKTVDAYGQLVIPGGIDANTNLHTPQKGMSP--VDGFYQGTRAALSGGTTTIMDHVLVEPGSSLLAVFDQMKETAEQTACCDFSLHLDIARWHDGLSEELETLVKDKGVNSFLFFMAYKDKYQSSDSQLYEAFGVLRDLGAIAQVHAENGDIIDEEQRKVLSLGITGPEGHALSHPEEVETEAVYRAITVAKQANCPLYITKVMSKSAADVIAKARKKGMVVYGEPITASLATDGSHYWSKDWATAAALVMSPPLNPDPSTPQYLTSLLACGDLQVTSSAQASFSTAQKAVGKDDFTLIPEGTNGIEERMAVVWDRAVFSGKMDENEFVAVTSTNAAKLFNMYPRKGRIAVGSDADIVVWNPKETRTVSAKTHNLTLEVNILEGLEFRGVPAVVISGGRVVLENGQLN--VTEGSGRFVPRKAFPDAV------YKRIKARSKMAETRGVPRG--------SYDGP----VHDVTSMMKSVPPTPTSRGPPCPKTQAGLRNLHQSGFTLAGSQIDDHIPRRSAQRIVAPPGGRSNI 568

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl2b (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:101155946])

HSP 1 Score: 296.59 bits (758), Expect = 3.784e-92
Identity = 193/569 (33.92%), Postives = 306/569 (53.78%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQL-NEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L++G  IVN D+ F +DV +E+ +IKQIG++++V G  K ID   ++++PGGID  T F + P+      D  +  + AALAGGTT I+  V  + G  L+++ +  +    SK  C+Y   + I        + METL +  G+N F + +  +      +A    V    ++L  + ++   +   +   +  ++  GI+GPEG   S   E E E + R + + +   C L + +VM++  A ++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D      +   + CGD+ +  S H     A R++GK DF  IP GV+G EER+S++WD+ V +G ++E +FV+ TSTNAAKIFNLYP +G IAVGS AD+V+W+P  T+ ISA S +   + NIFEG   +G P VVI  G +  +  N  +   +G  +  K     V  ++K    L E    G+ R + D  G   E+        V  K +  V S K +P K    P     RN+  S FSLSG+Q+DD  P R+T R   PPGG++N+
Sbjct:   17 RLLIRGAKIVNDDQSFCADVYMEDGVIKQIGENLIVPGGVKTIDAHGRMLMPGGIDVHTRFQM-PDRGMTAADDFYQGTKAALAGGTTMILDHVLPEPGVSLLSAFEQWREWADSKACCDYSLHIDITEWHKGIQEEMETLVKDHGVNSFLVYLAYKDIFQLTDAQVYEVFSVIRDLGAIAQVHAENGDIVAEEQRRILEQGITGPEGHVLSHPEEVEAEAVNRSVTVANQTNCPLYVTKVMSKSAADVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQVTGSAHCPFNTAQRAVGKDDFTLIPEGVNGTEERMSIIWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNSTVEYNIFEGTEVRGGPLVVISQGKIILEEGNLHVTEGSGRFVARKPFPDYVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTMTPVSSAKTSPAKQPSQPV----RNLHQSGFSLSGAQVDDNIPRRNTQRIVAPPGGRANI 569

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl5b (dihydropyrimidinase like 5 [Source:NCBI gene;Acc:101174151])

HSP 1 Score: 296.204 bits (757), Expect = 4.681e-92
Identity = 189/574 (32.93%), Postives = 312/574 (54.36%), Query Frame = 1

Query:   19 NFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDA-AIIRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            N  +M++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID + KL++PGGID S +     ++ + +D  +N + AAL GGTT ++ LV  +    L+++ +  ++   +K  C+Y   V +     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GISGPEG   SR  E E E  +R + + +   C + +  V +     +VA  KM+ + +++ET      LS  +Y+  +W  SA+ +  PP+R D +    +  +   D + +VASEH       R++GK DF  IPHGV+GV++R+S++W+RGV +G ++E  FV+ TS+NAAKI+N+YP +G I  G+ AD+V+W+P  T+TIS  +Q    D N++EG+ C GVP V I  G +  + + F+    +G+   L      +  KM + E  + +  +       D   VA+ I+         +  +  +D + +     R     G R++ +SSFSLSGSQ+DD  P RS+ R   PPGG+S+ I+
Sbjct:    4 NMGSMRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDASGKLVLPGGIDTSVHLQQTFMNASIQDDFYNGTKAALMGGTTMVMALVLPEQHCSLLDAYEKCRALADAKTCCDYSLHVGVTWWGPKVHNEMETLVREHGVNSFQMYMAYKDMMMLRDSELYQTLQTCKDIGAIARVHAENGELVAEGAKEALDLGISGPEGIEISRPEELESEATHRAITIANRARCPIYLVNVSSVSAGDMVAAAKMQDKVVYAETTVAHAVLSGMQYYHQDWAHSAAHVIVPPLRLDPNTPGYLMGLLANDTLSVVASEHRPFNTKQRALGKEDFTKIPHGVAGVQDRMSVIWERGVVTGKMDENRFVAVTSSNAAKIYNMYPRKGRIIPGADADVVVWDPDATKTISVTTQVQGGDFNLYEGMRCHGVPLVTISRGRLVCENSMFMCAEGSGKFYPLHTFPDYLYKKMVQREKTQSYKGVARDPYSGDVAKVANTIKR--------ELGLGPIDGESSNKASAR--IHQGVRDLHESSFSLSGSQVDDHIPKRSSARILAPPGGRSSGIW 567

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: crmp1 (dihydropyrimidinase-related protein 1 [Source:NCBI gene;Acc:101159888])

HSP 1 Score: 286.189 bits (731), Expect = 1.882e-88
Identity = 196/555 (35.32%), Postives = 295/555 (53.15%), Query Frame = 1

Query:   73 RKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNF---NLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVK-SMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            R F  DV IE+ +IKQ+G+++VV G  KVI+   +++IPGGID +T      L     D     + AALAGGTT II  V  + G  L+ + +  Q     +  C+Y   V I P  +E VK  +E L +  GIN FQ+ +  +      ++         K+L  ++ +   +   +   + +++  GI+GPEG   SR  E E E ++R + L +   C + I +VM++  A  +A+ + +G  +F E I   LA     Y+S NW ++A+ +T PP+  D      +   +  GD+ +V S H   + + ++IGK DF  IP G +GVEER+  +WD+ V  G ++E +FV+ TSTNAAKIFNLYP +G IAV S ADIVIW+P   +TI+A  Q    + NIFEG+ C+G P +V+  G V ++  +  I   TG  I  K        ++K    +    K G+TR + D       +  +    K I     +  +K +P   Q PPT    RN+  S+FSLSG+QIDD  P RS  R   PPGG+SN+
Sbjct:    1 RSFFGDVYIEDGLIKQVGENLVVPGGVKVIEANGRMVIPGGIDVNTCLMKTYLGTQPVDDFLQGTKAALAGGTTMIIDHVTPEPGESLLEAFERWQEAADKRACCDYSLHVDI-PLWNETVKDELEVLVQDKGINSFQVYMAYKDVYQMTDSQLYEAFSFLKQLGAVVLVHAENGDLIFEEQRKILGMGITGPEGHPLSRPEEVEAEAVFRAITLGNCVNCPVYITKVMSKSAADTIAQARRKGSVVFGEPITAGLATDGSHYWSKNWAKAAAYVTSPPLSPDPTTPEHLHTLLASGDLQVVGSSHCAYSTSQKAIGKDDFTLIPEGTNGVEERMGFVWDKAVAMGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVDSDADIVIWDPDIVKTITAKQQQSAAEYNIFEGLECRGGPALVLSQGRVVYEGGKLQIQQGTGRFIPRKPFPDYAFQRIKFRNQVSS--KQGVTRGVYDG-----PVHDVTPTPKYITP---SPSAKTSPTSHQ-PPTV---RNLHLSNFSLSGAQIDDNIPRRSGHRIVAPPGGRSNI 540

[Close]

BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl3 (dihydropyrimidinase-related protein 3 [Source:NCBI gene;Acc:101165934])

HSP 1 Score: 281.182 bits (718), Expect = 1.983e-85
Identity = 185/572 (32.34%), Postives = 300/572 (52.45%), Query Frame = 1

Query:   25 KTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKD-KMKRYECLREFGKM-GITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIR-STIRTNHPPGGKSNL 1701
            K+ ++L+KGG IVN D+ F +D+ +E+ +IKQIG +++V G  K I+   K++IPGGID  T+F +        D     S AALAGGTT I+  V  + G  L+ +    +     K  C+Y   V I    D   + +++L +  G+N FQ+ +  +      N+    +     E   ++++   +   +   +  ++  GI+GPEG   SR  E E E ++R + +     C L + +VM++  A ++++ + +G  +F E I  +L      Y+S NW ++A+ +T PP+  D      +   +  GD+ +  S H T + A ++IGK DF  IP GV+GVEER++++WD+ V +G ++E  FV+ TSTNAAKI NLYP +G IAVGS AD++IW+    RTI+A + +   + NIFEG+  +G P VVI  G +  +  +    +   R    I C    D   KR +  ++   +  + R + D  G  SE         + +    +  ++ +P K    P     RN+  S FSL+G    DE PIR +  R   PPGG+SN+
Sbjct:   97 KSDRLLIKGGRIVNDDQSFHADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHFQMPYRGTTTVDDFAQGSKAALAGGTTMIVDHVIPEPGTSLMEAYDQWRQWADEKACCDYSLHVDITHWNDSVKQEVDSLIKDKGVNSFQVYMAYKDYYQLSNSQLYEIFTFLAEKGGIVQVHAENGEIIAEEQARMLQMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAADIISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNTLLASGDLSVTGSAHCTFSVAQKAIGKDDFTQIPEGVNGVEERMALIWDKAVTTGKMDENMFVAITSTNAAKILNLYPRKGRIAVGSDADLIIWDTDSVRTITAKTHNSAAEYNIFEGMELRGAPLVVICQGKIVLEDGKLQVTSGAGRF---IPCSPFPDFAYKRVKARKQLAVLRAVPRGMYD--GPVSEF-------SMSRGGTPSASARTSPTKQ---PV----RNLHQSGFSLTGPPTPDEVPIRPAGRRIVVPPGGRSNI 649

[Close]

BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000028784.1 (SMESG000028784.1)

HSP 1 Score: 1082.78 bits (2799), Expect = 0.000e+0
Identity = 555/559 (99.28%), Postives = 557/559 (99.64%), Query Frame = 1

Query:   31 MKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            MKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPN+DECVKSME LARQFGINCFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPP+RNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINN HKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF
Sbjct:    1 MKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNDDECVKSMEKLARQFGINCFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPVRNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNSHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 559

[Close]

BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000028784.1 (SMESG000028784.1)

HSP 1 Score: 1078.54 bits (2788), Expect = 0.000e+0
Identity = 553/557 (99.28%), Postives = 555/557 (99.64%), Query Frame = 1

Query:   37 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPN+DECVKSME LARQFGINCFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPP+RNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINN HKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF
Sbjct:    1 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNDDECVKSMEKLARQFGINCFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPVRNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNSHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 557

[Close]

BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000002633.1 (SMESG000002633.1)

HSP 1 Score: 340.502 bits (872), Expect = 6.304e-109
Identity = 215/573 (37.52%), Postives = 327/573 (57.07%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEI-----NANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQN-DTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMK-RYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINP--LKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            ++ +KG  IVN DR F +DV IE+ IIKQ+G ++V+ G  + ++   KL+IPGGID  T+     +     D  ++ + AALAGGTT II  V  Q G  L++S    +    SKV C+YG  V +    +     ME LA + GIN F++ +  +      +     V KKCK +  L ++   +   +E    ELI+ GI+GPEG   SR  E E E   R + L     C L +  VM++  A +++  + +G+ +F E I   L      Y  + W  +A  +  PP+RND++ +  +++ +  GD++   ++H     + +++GK DFR+IP+GV+GVE+R+S++W++GV +GI++ C+FV+ TSTNAAKIFN+YP +G I +GS AD+V+WNP   RTISA S H QN D NIFEG+ C GV E+VI  G V  +  N  +   TG+ +     C  V +K+K R +C +      + R+  D   V    + + N +     D  +  + I+   +  +RP TSGG R+MQDSSF+LSG+QIDD  P RS IRT  PPGG +  ++
Sbjct:   23 RLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISA-STHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANK-VERQPYDGP-VEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 592

[Close]

BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000060188.1 (SMESG000060188.1)

HSP 1 Score: 164.466 bits (415), Expect = 1.840e-43
Identity = 155/586 (26.45%), Postives = 271/586 (46.25%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN------LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSK-VLCNYGF---------CVQIDPNEDECVKSMETLARQFGIN--CFQMTIGNEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVM-NEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA-----IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKP--------IRSTIRTNHPPGGKS 1695
            K+L+K G ++N D  + +DVLIEN  I  I ++I  S   + ID T   ++PGG+D  TNF       +SP +       ++          + ++K++S  E       ++ D+ SK ++CN             ++ + NE    KS+  L R   ++  C  + I +E        L  C++   L  +   +   +  +E+EL+  G++GPEG + SR  + E E ++R+L +  +  C +   +V     + K++   +     I   T   AL  ++ KY   NW  +AS +T P ++ +++       ++ ++    I+ VAS H       ++ G+ DFR I  G +GV+ R+ +LWD+ VKSG +    FV+  ST  AK+ N+YP +G I++GS ADI++W   K  ++S  S     D N+FE + C   P+ VIVNG V     +  GN T      K + Q+V   ++       F K  I  ++S+ +    E +    P+             I+P    +        +M ++     G   +D+K         IR++++T  PPGG +
Sbjct:    7 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSL-AECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYE----MEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDE---ELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKNTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW---KGDSVSH-SNFEAGDINVFEDVICHSGPKYVIVNGIVVL---DHEGNFTAS----KGSGQIVSPSLETMNSY--FQKQLINYKLSNEV----EKKIAREPYD---------GPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 558

[Close]

BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000060188.1 (SMESG000060188.1)

HSP 1 Score: 164.466 bits (415), Expect = 2.376e-43
Identity = 155/586 (26.45%), Postives = 271/586 (46.25%), Query Frame = 1

Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN------LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSK-VLCNYGF---------CVQIDPNEDECVKSMETLARQFGIN--CFQMTIGNEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVM-NEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA-----IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKP--------IRSTIRTNHPPGGKS 1695
            K+L+K G ++N D  + +DVLIEN  I  I ++I  S   + ID T   ++PGG+D  TNF       +SP +       ++          + ++K++S  E       ++ D+ SK ++CN             ++ + NE    KS+  L R   ++  C  + I +E        L  C++   L  +   +   +  +E+EL+  G++GPEG + SR  + E E ++R+L +  +  C +   +V     + K++   +     I   T   AL  ++ KY   NW  +AS +T P ++ +++       ++ ++    I+ VAS H       ++ G+ DFR I  G +GV+ R+ +LWD+ VKSG +    FV+  ST  AK+ N+YP +G I++GS ADI++W   K  ++S  S     D N+FE + C   P+ VIVNG V     +  GN T      K + Q+V   ++       F K  I  ++S+ +    E +    P+             I+P    +        +M ++     G   +D+K         IR++++T  PPGG +
Sbjct:   10 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSL-AECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYE----MEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDE---ELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKNTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW---KGDSVSH-SNFEAGDINVFEDVICHSGPKYVIVNGIVVL---DHEGNFTAS----KGSGQIVSPSLETMNSY--FQKQLINYKLSNEV----EKKIAREPYD---------GPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 561

The following BLAST results are available for this feature:

BLAST of Dihydropyrimidinase vs. Ensembl Human
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
BLAST of Dihydropyrimidinase vs. Ensembl Fly
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
BLAST of Dihydropyrimidinase vs. TrEMBL
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
BLAST of Dihydropyrimidinase vs. Ensembl Yeast
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
BLAST of Dihydropyrimidinase vs. Planmine SMEST

BLAST of Dihydropyrimidinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DPYSL5	7.487e-97	34.54	dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc...	[more]
DPYSL5	7.487e-97	34.54	dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc...	[more]
DPYSL5	7.487e-97	34.54	dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc...	[more]
DPYSL2	2.038e-96	34.45	dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc...	[more]
DPYSL2	1.017e-95	34.26	dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc...	[more]

BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dhp-2	5.515e-81	36.83	Dihydropyrimidinase 2 [Source:UniProtKB/Swiss-Pro...	[more]
dhp-1	1.018e-78	34.16	Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Pro...	[more]
dhp-1	1.018e-78	34.16	Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Pro...	[more]
dhp-1	1.018e-78	34.16	Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Pro...	[more]
unc-33	3.262e-50	29.33	pep chromosome:WBcel235:IV:3518147:3525572:1 gene:...	[more]

BLAST of Dihydropyrimidinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
CRMP	7.219e-76	31.03	gene:FBgn0023023 transcript:FBtr0114453	[more]
CRMP	2.655e-75	30.80	gene:FBgn0023023 transcript:FBtr0089686	[more]
CRMP	9.309e-25	29.67	gene:FBgn0023023 transcript:FBtr0089685	[more]

BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dpysl5a	1.598e-96	33.92	dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-G...	[more]
dpysl5a	1.598e-96	33.92	dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-G...	[more]
dpysl4	1.094e-95	34.09	dihydropyrimidinase like 4 [Source:ZFIN;Acc:ZDB-GE...	[more]
dpysl5a	2.111e-95	33.22	dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-G...	[more]
crmp1	2.310e-95	35.65	collapsin response mediator protein 1 [Source:ZFIN...	[more]

BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dpysl4	1.461e-95	34.33	dihydropyrimidinase like 4 [Source:NCBI gene;Acc:5...	[more]
dpysl4	1.478e-95	34.20	dihydropyrimidinase like 4 [Source:NCBI gene;Acc:5...	[more]
dpysl4	1.639e-95	34.33	dihydropyrimidinase like 4 [Source:NCBI gene;Acc:5...	[more]
dpysl4	2.533e-95	34.03	dihydropyrimidinase like 4 [Source:NCBI gene;Acc:5...	[more]
bco2	2.019e-94	34.84	beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-G...	[more]

BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Dpysl2	3.793e-96	34.09	dihydropyrimidinase-like 2 [Source:MGI Symbol;Acc:...	[more]
Dpysl4	5.326e-96	34.74	dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:...	[more]
Dpysl4	5.326e-96	34.74	dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:...	[more]
Dpysl4	1.033e-95	34.74	dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:...	[more]
Dpysl4	1.033e-95	34.74	dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:...	[more]

BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q90635\|DPYL2_CHICK	1.574e-97	34.68	Dihydropyrimidinase-related protein 2 OS=Gallus ga...	[more]
sp\|Q9BPU6\|DPYL5_HUMAN	3.595e-96	34.54	Dihydropyrimidinase-related protein 5 OS=Homo sapi...	[more]
sp\|O02675\|DPYL2_BOVIN	3.686e-96	34.45	Dihydropyrimidinase-related protein 2 OS=Bos tauru...	[more]
sp\|Q62951\|DPYL4_RAT	4.789e-96	34.92	Dihydropyrimidinase-related protein 4 (Fragment) O...	[more]
sp\|Q9JHU0\|DPYL5_RAT	7.401e-96	34.72	Dihydropyrimidinase-related protein 5 OS=Rattus no...	[more]

BLAST of Dihydropyrimidinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
K1PGY5	1.497e-106	37.30	Dihydropyrimidinase OS=Crassostrea gigas OX=29159 ...	[more]
A0A1W7RAR0	1.795e-105	35.28	Dihydropyrimidinase OS=Hadrurus spadix OX=141984 P...	[more]
A0A267FG46	5.373e-103	35.20	Amidohydro-rel domain-containing protein OS=Macros...	[more]
A0A183TGQ2	9.600e-103	35.89	Dihydropyrimidinase OS=Schistocephalus solidus OX=...	[more]
A0A3P7D5Z0	9.911e-103	35.89	Amidohydro-rel domain-containing protein OS=Schist...	[more]

BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dpysl4	9.858e-95	33.22	dihydropyrimidinase like 4 [Source:NCBI gene;Acc:1...	[more]
dpysl4	1.636e-93	33.22	dihydropyrimidinase like 4 [Source:NCBI gene;Acc:1...	[more]
dpysl5a	1.076e-92	33.80	dihydropyrimidinase like 5 [Source:NCBI gene;Acc:1...	[more]
dpysl2b	2.291e-92	33.92	dihydropyrimidinase-related protein 2 [Source:NCBI...	[more]
dpysl2b	6.746e-92	33.74	dihydropyrimidinase-related protein 2 [Source:NCBI...	[more]

BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
dpysl3	6.680e-74	31.59	dihydropyrimidinase like 3 [Source:NCBI gene;Acc:5...	[more]
ENSPMAT00000006054.1	2.944e-49	37.26	pep scaffold:Pmarinus_7.0:GL477305:540:7425:1 gene...	[more]
dpysl2b	8.917e-24	29.12	dihydropyrimidinase like 2b [Source:ZFIN;Acc:ZDB-G...	[more]

BLAST of Dihydropyrimidinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO46551	1.785e-93	34.99	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49158	9.912e-10	25.56	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dpysl4	4.772e-97	33.74	dihydropyrimidinase-related protein 2 [Source:NCBI...	[more]
dpysl2b	3.784e-92	33.92	dihydropyrimidinase-related protein 2 [Source:NCBI...	[more]
dpysl5b	4.681e-92	32.93	dihydropyrimidinase like 5 [Source:NCBI gene;Acc:1...	[more]
crmp1	1.882e-88	35.32	dihydropyrimidinase-related protein 1 [Source:NCBI...	[more]
dpysl3	1.983e-85	32.34	dihydropyrimidinase-related protein 3 [Source:NCBI...	[more]

BLAST of Dihydropyrimidinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000028784.1	0.000e+0	99.28	SMESG000028784.1	[more]
SMESG000028784.1	0.000e+0	99.28	SMESG000028784.1	[more]
SMESG000002633.1	6.304e-109	37.52	SMESG000002633.1	[more]
SMESG000060188.1	1.840e-43	26.45	SMESG000060188.1	[more]
SMESG000060188.1	2.376e-43	26.45	SMESG000060188.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30022905 ID=SMED30022905|Name=Dihydropyrimidinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1893bp
ATGGGTGAATACATTTTAAATTTCAAAACTATGAAAATGCTGTTAAAAGG
AGGATATATTGTAAATAGTGACAGAAAATTTCAGTCTGACGTACTAATTG
AAAATAATATAATCAAACAAATTGGCCAAAGCATTGTTGTAAGTGGTGAC
ACTAAAGTGATTGATGTAACAAACAAACTTATCATTCCCGGTGGCATAGA
TCCAAGCACCAATTTTAATTTATCTCCGAACCACAGAGATATTCTTCACA
ATGAATCAATGGCTGCCTTAGCCGGCGGAACAACGACTATAATTACTCTT
GTTAAAGAACAAAGCGGTGCTGAGTTAGTAAATTCATTGAAAGCACTTCA
GTCAGATCTAAAATCGAAAGTATTGTGTAATTATGGATTTTGTGTGCAAA
TTGATCCAAATGAGGACGAATGCGTAAAATCCATGGAAACATTGGCACGA
CAATTTGGAATAAATTGCTTCCAAATGACAATAGGAAATGAAATAAACGC
TAACACTGTTTCAGTTCTGAAAAAATGTAAAGAATTACAATGCTTACTCA
AATTGCGAGTCCATGATTCTACATACCTTGAAGCAGTGGAAGAAGAATTA
ATAACTGCAGGCATTTCTGGACCAGAAGGCTTCTTCCAATCTCGATGTAT
TGAAAATGAAATGGAGCAATTATATCGAATTTTAAAGTTAAACCATGTTT
TTCCTTGTTGTCTGATCATACCACAAGTTATGAACGAAGACATTGCAAAA
CTTGTCGCAAAAATGAAAATGGAAGGACGACCTATCTTTTCCGAAACCAT
TCCACCCGCTCTTGCTTTATCAAGTCACAAGTACTTCTCAAATAATTGGG
ATGAATCAGCATCATTAATTACAGATCCACCTATACGAAATGATCAGGAT
GCAGCAATAATACGAAGCATTCATTGTGGAGATATCGACATGGTGGCATC
GGAACATACAACAATAACGAATGCAGATCGATCGATTGGGAAGAGAGATT
TTAGAAACATACCTCATGGAGTTTCTGGCGTTGAGGAGAGATTGTCAATG
CTGTGGGATAGAGGAGTGAAATCTGGAATTATAAATGAATGCGAATTTGT
TTCGGCAACAAGTACAAACGCTGCAAAAATCTTCAACCTTTATCCAGACC
GAGGACACATTGCAGTTGGGAGCGTAGCCGATATTGTTATTTGGAATCCA
GTAAAAACAAGAACCATTTCTGCTTTATCTCAACACTTGCAAAACGATAC
AAATATTTTTGAAGGGATTTCTTGTCAAGGAGTTCCGGAAGTTGTAATTG
TGAATGGATCTGTCAAATTTCAGTTGAATGAGTTCATTGGAAACGCGACC
GGAGAAAGAATAGATTTAAAAATTAATTGTCAAGTTGTAAAAGATAAAAT
GAAGAGATATGAATGCCTACGAGAGTTTGGGAAAATGGGAATAACTCGGG
AAATCAGTGATAATATCGGAGTTGCCAGTGAAATTAGAACCATAAATAAT
CCACATAAAGTGATTCAGAAAGATATTGTAACTGTCGATAGTAAAATTAA
TCCGCTTAAAATGCAAAGACCTCCAACAAGTGGCGGAAATAGAAATATGC
AAGACTCAAGTTTTTCATTAAGTGGATCTCAAATCGACGACGAAAAGCCA
ATTCGAAGTACAATAAGAACAAACCACCCGCCCGGAGGAAAATCAAATCT
GATATTTTGATGTGAAAATTAAACAATTTATTAATCAGTCTTTTAATTTA
ATATTTAATTCAATAATTTTAGATTTTGATGTTGTTTAAATAATTGATTT
CAATTGATTTTTCTATGGATATTTTGTTTATTAGAATGGGTTTTTTTTAA
TTAATTATTTATGTTGGCATTGAATAAAATTTGATTAATTTCA

protein sequence of SMED30022905-orf-1

>SMED30022905-orf-1 ID=SMED30022905-orf-1|Name=SMED30022905-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=570bp
MGEYILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGD
TKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMAALAGGTTTIITL
VKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLAR
QFGINCFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEEL
ITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAK
LVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQD
AAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSM
LWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNP
VKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNAT
GERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINN
PHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKP
IRSTIRTNHPPGGKSNLIF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR011059	Metal-dep_hydrolase_composite
IPR006680	Amidohydro-rel
IPR032466	Metal_Hydrolase

Vocabulary: **molecular function**
Term	Definition
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016787	hydrolase activity

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006680	Amidohydrolase-related	PFAM	PF01979	Amidohydro_1	coord: 59..436 e-value: 2.9E-13 score: 49.9
IPR011059	Metal-dependent hydrolase, composite domain superfamily	GENE3D	G3DSA:2.30.40.10		coord: 11..462 e-value: 2.8E-136 score: 456.7
IPR011059	Metal-dependent hydrolase, composite domain superfamily	SUPERFAMILY	SSF51338	Composite domain of metallo-dependent hydrolases	coord: 9..447
None	No IPR available	GENE3D	G3DSA:3.20.20.140		coord: 62..424 e-value: 2.8E-136 score: 456.7
None	No IPR available	PANTHER	PTHR11647	AMINOHYDROLASE	coord: 8..473
None	No IPR available	PANTHER	PTHR11647:SF1	COLLAPSIN RESPONSE MEDIATOR PROTEIN	coord: 8..473
IPR032466	Metal-dependent hydrolase	SUPERFAMILY	SSF51556	Metallo-dependent hydrolases	coord: 62..381

Main menu

Dihydropyrimidinase

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Owlery

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