Dihydropyrimidinase

Overview
NameDihydropyrimidinase
Smed IDSMED30022905
Length (bp)1893
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Dihydropyrimidinase (SMED30022905) t-SNE clustered cells

Violin plots show distribution of expression levels for Dihydropyrimidinase (SMED30022905) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dihydropyrimidinase (SMED30022905) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dihydropyrimidinase (SMED30022905) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30022905

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
neuronSMED30022905SMESG000028784.1 SMESG000061889.1 dd_Smed_v4_3519_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neuronSMED30022905SMESG000028784.1 SMESG000061889.1 dd_Smed_v4_3519_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
parenchymal cellSMED30022905SMESG000028784.1 SMESG000061889.1 dd_Smed_v4_3519_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
headSMED30022905SMESG000028784.1 SMESG000061889.1 dd_Smed_v6_3519_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL5 (dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc:HGNC:20637])

HSP 1 Score: 309.301 bits (791), Expect = 7.487e-97
Identity = 200/579 (34.54%), Postives = 319/579 (55.09%), Query Frame = 1
Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAI-IRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKM-KRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVT--VDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            + N  ++++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL+IPGGID ST+F+   ++    D  ++ + AAL GGTT II  V       LV++ +  +     KV C+Y   V I     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GI+GPEG   SR  E E E  +R++ + +   C + +  V +     ++A  KM+G+ + +ET      L+   Y+  +W  +A+ +T PP+R D + +  + S+   D +++VAS+H   T   +++GK DF  IPHGVSGV++R+S++W+RGV  G ++E  FV+ TS+NAAK+ NLYP +G I  G+ AD+V+W+P  T+TISA +Q    D N++E + C GVP V I  G V ++   F+    TG+   L+     V  K+ +R + L+  G         D      ++  + +P K   K++ T   D+   P+        GG R++ +SSFSLSGSQIDD  P R++ R   PPGG+S+ I+
Sbjct:    2 LANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRG--------VDRTPYLGDVAVVVHPGK---KEMGTPLADTPTRPVTRH-----GGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564          
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL5 (dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc:HGNC:20637])

HSP 1 Score: 309.301 bits (791), Expect = 7.487e-97
Identity = 200/579 (34.54%), Postives = 319/579 (55.09%), Query Frame = 1
Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAI-IRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKM-KRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVT--VDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            + N  ++++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL+IPGGID ST+F+   ++    D  ++ + AAL GGTT II  V       LV++ +  +     KV C+Y   V I     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GI+GPEG   SR  E E E  +R++ + +   C + +  V +     ++A  KM+G+ + +ET      L+   Y+  +W  +A+ +T PP+R D + +  + S+   D +++VAS+H   T   +++GK DF  IPHGVSGV++R+S++W+RGV  G ++E  FV+ TS+NAAK+ NLYP +G I  G+ AD+V+W+P  T+TISA +Q    D N++E + C GVP V I  G V ++   F+    TG+   L+     V  K+ +R + L+  G         D      ++  + +P K   K++ T   D+   P+        GG R++ +SSFSLSGSQIDD  P R++ R   PPGG+S+ I+
Sbjct:    2 LANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRG--------VDRTPYLGDVAVVVHPGK---KEMGTPLADTPTRPVTRH-----GGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564          
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL5 (dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc:HGNC:20637])

HSP 1 Score: 309.301 bits (791), Expect = 7.487e-97
Identity = 200/579 (34.54%), Postives = 319/579 (55.09%), Query Frame = 1
Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAI-IRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKM-KRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVT--VDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            + N  ++++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL+IPGGID ST+F+   ++    D  ++ + AAL GGTT II  V       LV++ +  +     KV C+Y   V I     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GI+GPEG   SR  E E E  +R++ + +   C + +  V +     ++A  KM+G+ + +ET      L+   Y+  +W  +A+ +T PP+R D + +  + S+   D +++VAS+H   T   +++GK DF  IPHGVSGV++R+S++W+RGV  G ++E  FV+ TS+NAAK+ NLYP +G I  G+ AD+V+W+P  T+TISA +Q    D N++E + C GVP V I  G V ++   F+    TG+   L+     V  K+ +R + L+  G         D      ++  + +P K   K++ T   D+   P+        GG R++ +SSFSLSGSQIDD  P R++ R   PPGG+S+ I+
Sbjct:    2 LANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRG--------VDRTPYLGDVAVVVHPGK---KEMGTPLADTPTRPVTRH-----GGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564          
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL2 (dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014])

HSP 1 Score: 308.531 bits (789), Expect = 2.038e-96
Identity = 196/569 (34.45%), Postives = 309/569 (54.31%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+  ++++IPGGID  T F + P+      D     + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + ME L +  G+N F + +  +      +     VL   +++  + ++   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAK+FNLYP +G IAVGS AD+VIW+P   +TISA + +   + NIFEG+ C+G P VVI  G +  +     +   +G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K Q PP     RN+  S FSLSG+QIDD  P R+T R   PPGG++N+
Sbjct:   16 RLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQM-PDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTVTPASSAKTSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANI 568          
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL2 (dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014])

HSP 1 Score: 309.686 bits (792), Expect = 1.017e-95
Identity = 197/575 (34.26%), Postives = 313/575 (54.43%), Query Frame = 1
Query:   16 LNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            +N ++ ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+  ++++IPGGID  T F + P+      D     + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + ME L +  G+N F + +  +      +     VL   +++  + ++   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAK+FNLYP +G IAVGS AD+VIW+P   +TISA + +   + NIFEG+ C+G P VVI  G +  +     +   +G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K Q PP     RN+  S FSLSG+QIDD  P R+T R   PPGG++N+
Sbjct:  115 INDQSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQM-PDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTVTPASSAKTSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANI 673          
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-2 (Dihydropyrimidinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q18677])

HSP 1 Score: 265.388 bits (677), Expect = 5.515e-81
Identity = 172/467 (36.83%), Postives = 257/467 (55.03%), Query Frame = 1
Query:   31 MKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETL-ARQFGINCFQMTI---GNEINANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQD--AAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKF---QLNEFIGNATGERIDLKINCQVV 1389
            M +L+K G IVN D  F+SDVL+ +  I +I  SI  +   +V+D T++L+IPGGIDP T+  L       +D  H  + AA+AGGTT II  V    G  L+ +    +     KV+C+YG  + I     E  K ME +   ++GIN F+  +   G  +  +        +  +     RVH  + + +    E L+++GI+GPEG  QSR  E E E  +R   +     C L +  VM++  A  +A  + +G  +F E I   LA     Y++ +W  +A  +  PP+  D    +A+++ +  G++ + A+++ T     +S+GK DF  IP+GV+GVE+R+S++WD+GV +GII+   FV+ TST AAKIFN YP +G IAVGS ADIVIWN   TRTIS  + H   D NIFEG+   GVPE+ I  G   +   QL    G  +G+ I L  + Q+V
Sbjct:    1 MSLLIKNGTIVNDDAIFKSDVLVLDGRIVEIAPSIQPTPGLEVVDATDRLVIPGGIDPHTHMQLPFMGEIAKDDFHRGTEAAVAGGTTMIIDFVIPTKGESLLVAYDRWRGWADPKVVCDYGLSMAITSWGPEIAKEMEIVTGAEYGINSFKFFLAYAGVFMVRDEEFYQGMIQCAKLRALARVHAENGSVIAERCEHLLSSGITGPEGHTQSRPEELEAEATFRACTMASQANCPLYVVHVMSKGAAAAIAHHRKKGAVVFGEPIAAGLATDGSHYYNEDWLHAARYVMSPPLSRDPSTPSALMKLLAAGELHLTATDNCTFDCQQKSLGKDDFTKIPNGVNGVEDRMSVVWDKGVHAGIIDPMRFVAVTSTMAAKIFNCYPQKGRIAVGSDADIVIWNANATRTISKDTHHHAIDFNIFEGMQVHGVPEITISRGRTVWANGQLKTVQG--SGQFIPLAPDSQIV 465          
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-1 (Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21773])

HSP 1 Score: 258.455 bits (659), Expect = 1.018e-78
Identity = 152/445 (34.16%), Postives = 243/445 (54.61%), Query Frame = 1
Query:   37 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXV------KEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETL-ARQFGINCFQMTIGNEINANTVSVX------XXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKF 1320
            +++K G +VN D  F++DVL+ N II ++  +I    DT+VID T++L+IPGGIDP T+  + P   ++  ++ +           T++        ++G  L+      +S    KV C+YG  V I     E  + M  + + +FG+N F+  +  E   NT+ V          +  +     RVH  + + ++  E +L+  G++GPEG  QSR  E E E   R   L     C + I  VM +  A  ++  + +G  +F E I   LAL    Y++ +W  +A  +  PP+  D      +++ +  G++ +  +++ T     +S+GK +F  IP+G++GVE+R+S++W++GV SGII+   +VS TS+ AAKIFN+YP +G IAVGS ADIVI+NP  TRTIS  + H   D NIFEGI+C GV EV I  G + +
Sbjct:    5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQM-PYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYE---NTLMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAISHHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNLDFNIFEGINCHGVAEVTISRGRIVW 445          
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-1 (Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21773])

HSP 1 Score: 258.455 bits (659), Expect = 1.018e-78
Identity = 152/445 (34.16%), Postives = 243/445 (54.61%), Query Frame = 1
Query:   37 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXV------KEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETL-ARQFGINCFQMTIGNEINANTVSVX------XXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKF 1320
            +++K G +VN D  F++DVL+ N II ++  +I    DT+VID T++L+IPGGIDP T+  + P   ++  ++ +           T++        ++G  L+      +S    KV C+YG  V I     E  + M  + + +FG+N F+  +  E   NT+ V          +  +     RVH  + + ++  E +L+  G++GPEG  QSR  E E E   R   L     C + I  VM +  A  ++  + +G  +F E I   LAL    Y++ +W  +A  +  PP+  D      +++ +  G++ +  +++ T     +S+GK +F  IP+G++GVE+R+S++W++GV SGII+   +VS TS+ AAKIFN+YP +G IAVGS ADIVI+NP  TRTIS  + H   D NIFEGI+C GV EV I  G + +
Sbjct:    5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQM-PYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYE---NTLMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAISHHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNLDFNIFEGINCHGVAEVTISRGRIVW 445          
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-1 (Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21773])

HSP 1 Score: 258.455 bits (659), Expect = 1.018e-78
Identity = 152/445 (34.16%), Postives = 243/445 (54.61%), Query Frame = 1
Query:   37 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXV------KEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETL-ARQFGINCFQMTIGNEINANTVSVX------XXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKF 1320
            +++K G +VN D  F++DVL+ N II ++  +I    DT+VID T++L+IPGGIDP T+  + P   ++  ++ +           T++        ++G  L+      +S    KV C+YG  V I     E  + M  + + +FG+N F+  +  E   NT+ V          +  +     RVH  + + ++  E +L+  G++GPEG  QSR  E E E   R   L     C + I  VM +  A  ++  + +G  +F E I   LAL    Y++ +W  +A  +  PP+  D      +++ +  G++ +  +++ T     +S+GK +F  IP+G++GVE+R+S++W++GV SGII+   +VS TS+ AAKIFN+YP +G IAVGS ADIVI+NP  TRTIS  + H   D NIFEGI+C GV EV I  G + +
Sbjct:    5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQM-PYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYE---NTLMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAISHHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNLDFNIFEGINCHGVAEVTISRGRIVW 445          
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: unc-33 (pep chromosome:WBcel235:IV:3518147:3525572:1 gene:WBGene00006769.1 transcript:Y37E11C.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-33)

HSP 1 Score: 185.652 bits (470), Expect = 3.262e-50
Identity = 127/433 (29.33%), Postives = 231/433 (53.35%), Query Frame = 1
Query:   37 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDL-KSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNE 1332
            +L+K   IVN D  F +D+LIE+ II+ +  ++      +V+D   KL +P GID  T   ++ +  D L     +A+AGGT TI+ +V+ +    +V+++K +++ L KS + C+    V I    D C + M  L +  GIN F +   +  +   + + +  K L  L+++   + + +  +E++++  G++GPEGF QSR    E +++  +  L ++  C + I QV + D    + K +  G    +E    A+       FS +   +++ +TD P+R      +I ++    + +  S H  + +A R +  +DF     G +G EER++++W+R V+SG I+   FV+ TSTNAAK+FN+YP +G IAVG+ AD+VIW+    R + +       + ++++G++   V    IV G + +Q  E
Sbjct:  160 LLVKNAQIVNDDAIFVADILIEDGIIQNVAPNLEAPEGAEVLDAAGKLALPAGIDVYTQ--VTDSSVDDLSTGCKSAIAGGTGTIVEVVRPRGAESVVSAVKRVKNQLEKSGISCHVALSVAI---TDFCEQEMSELVKNEGINSFVLDGVSLTDDKLLELFEHVKRLGALIRVVPENKSIVAMLEKKMLKLGVTGPEGFPQSRPESLEADRVSGVCVLGNLASCPISIVQVSSADSLAAIEKARASGALAHAEIASAAVTADGSALFSQDLRFASAHLTDVPLRRGAPDRMIGALSTQPLVVCTSGHRPVNSATR-VAAKDFAIAQKGSTGAEERMAVVWERAVRSGRIDAMRFVAVTSTNAAKMFNMYPKKGRIAVGADADLVIWDASGKRVLESSRAQSSQENSMYDGLTVHSVVTATIVGGKIAYQNGE 586          
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0114453)

HSP 1 Score: 254.218 bits (648), Expect = 7.219e-76
Identity = 184/593 (31.03%), Postives = 302/593 (50.93%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQS--IVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHR---DILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEI-----NANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNED--IAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQL-NEFIGNATGERIDLKINCQVVKD---------------KMKRYECLREFGKMG--------ITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSN 1698
            ++ +K G IVN D+ F++DV IE+ IIK +G S  I + G  + ID +  +IIPGGIDP T+  L        D  ++ + AA+AGGTT II  V       ++ +    +S    KV C+YG  V I        + +  L ++ G+N F+  +  +      +++ + V ++ + L  +  +   +   +    + L+  GI+GPEG   SR  E E E ++R   L H   C L +  VM++   I    A+ +  GR I  ET+  AL   +       +D  A+ +  PP+R D+     +++ +   D+ +  S++ T     +++GK DF  IP+GV+GVE+R+S++W++GV +G+++ C FV+ TSTNAAKIFN+YP +G IAVGS ADIVIWNP  TRTIS  + H   D NIFEG++  GV E V+V G +  +  N  +    G  I   +    V D               + +     + F ++         I+  ++ N+ + +E    + P         +V  +++           G R++Q+SSFS+  S+  D   +R+ I+  +PPGGKS+
Sbjct:   21 RVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTP---------SVRGRVD-----------GKRDLQESSFSI--SEELDRSGVRACIKVKNPPGGKSS 591          
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0089686)

HSP 1 Score: 252.677 bits (644), Expect = 2.655e-75
Identity = 182/591 (30.80%), Postives = 300/591 (50.76%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQS--IVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHR---DILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEI-----NANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQL-NEFIGNATGERIDLKINCQVVKD---------------KMKRYECLREFGKMG--------ITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSN 1698
            ++ +K G IVN D+ F++DV IE+ IIK +G S  I + G  + ID +  +IIPGGIDP T+  L        D  ++ + AA+AGGTT II  V       ++ +    +S    KV C+YG  V I        + +  L ++ G+N F+  +  +      +++ + V ++ + L  +  +   +   +    + L+  GI+GPEG   SR  E E E ++R   L H     L +  + ++  A+LV + +  G  +F ET+  +L  S       +       IT PPIR   +    +++S+   D+ +  S++ T     +++GK DF  IP+GV+GVE+R+S++W++GV +G+++ C FV+ TSTNAAKIFN+YP +G IAVGS ADIVIWNP  TRTIS  + H   D NIFEG++  GV E V+V G +  +  N  +    G  I   +    V D               + +     + F ++         I+  ++ N+ + +E    + P         +V  +++           G R++Q+SSFS+  S+  D   +R+ I+  +PPGGKS+
Sbjct:   21 RVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQMKTPLFVSGLTSKSSAELVGRARRSGYCVFGETLASSLGRSMSAVPKGD---RIYAITSPPIRESAETPRQLMKSLAYDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTP---------SVRGRVD-----------GKRDLQESSFSI--SEELDRSGVRACIKVKNPPGGKSS 586          
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0089685)

HSP 1 Score: 106.301 bits (264), Expect = 9.309e-25
Identity = 89/300 (29.67%), Postives = 147/300 (49.00%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQS--IVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHR---DILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEI-----NANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNED--IAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQ 897
            ++ +K G IVN D+ F++DV IE+ IIK +G S  I + G  + ID +  +IIPGGIDP T+  L        D  ++ + AA+AGGTT II  V       ++ +    +S    KV C+YG  V I        + +  L ++ G+N F+  +  +      +++ + V ++ + L  +  +   +   +    + L+  GI+GPEG   SR  E E E ++R   L H   C L +  VM++   I    A+ +  GR I  ET+  AL   +       +D  A+ +  PP+R D+
Sbjct:   21 RVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDK 320          
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl5a (dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-GENE-030131-3136])

HSP 1 Score: 308.145 bits (788), Expect = 1.598e-96
Identity = 194/572 (33.92%), Postives = 311/572 (54.37%), Query Frame = 1
Query:   28 TMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPT-SGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            T+++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL++PGGID S + N   ++    D  ++ + AALAGGTT +I  V  +    L+++ +  +S   +K  C+Y   + +     +    METL R  G+N FQM +  +   +  ++                RVH  +   +     E +  GISGPEG   SR  E E E ++R + + +   C + +  V +     ++A  KM+G+ +  ET      L+  +Y+  +W  +A+ +T PP+R D +    ++  +    +++V S+H   T   +++GK DF  IPHGV GV++R+S++W+RGV  G ++E  FV+ TS+NAAKI+NLYP +G I  G+ AD+V+W+P  TRTIS  +Q    D N++E + C GVP V I  G V ++   F     +G+   L+     +  KM + E  +     G+ R          ++  + N  K   KD+   D  +NP    RP T  GG R++ +SSFSLSG+QIDD  P R++ R   PPGG+S+ I+
Sbjct:    7 TVRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLNESFMNGTTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKARSHADAKACCDYALHMGVTWWGPKARAQMETLVRDKGVNSFQMYMAYKDMYMLRDSELFQALQNCKDIGAVARVHAENGELVAEGAREALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLASAKMQGKVVHGETTTAHAVLNGMQYYHQDWAHAAAFVTVPPLRLDPNTPNYLLSLLGNDTLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSVMWERGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPESTRTISVTTQWQGGDVNLYENLRCHGVPLVTISRGRVVYENGIFTCAEGSGKFYPLRTFPDYLYKKMVQREKCQAL--KGVER-----TPYTGDVAAVQNSGK---KDLGPADGDMNP----RPCTRHGGVRDLHESSFSLSGAQIDDNVPKRASARILAPPGGRSSGIW 564          
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl5a (dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-GENE-030131-3136])

HSP 1 Score: 308.145 bits (788), Expect = 1.598e-96
Identity = 194/572 (33.92%), Postives = 311/572 (54.37%), Query Frame = 1
Query:   28 TMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPT-SGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            T+++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL++PGGID S + N   ++    D  ++ + AALAGGTT +I  V  +    L+++ +  +S   +K  C+Y   + +     +    METL R  G+N FQM +  +   +  ++                RVH  +   +     E +  GISGPEG   SR  E E E ++R + + +   C + +  V +     ++A  KM+G+ +  ET      L+  +Y+  +W  +A+ +T PP+R D +    ++  +    +++V S+H   T   +++GK DF  IPHGV GV++R+S++W+RGV  G ++E  FV+ TS+NAAKI+NLYP +G I  G+ AD+V+W+P  TRTIS  +Q    D N++E + C GVP V I  G V ++   F     +G+   L+     +  KM + E  +     G+ R          ++  + N  K   KD+   D  +NP    RP T  GG R++ +SSFSLSG+QIDD  P R++ R   PPGG+S+ I+
Sbjct:    7 TVRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLNESFMNGTTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKARSHADAKACCDYALHMGVTWWGPKARAQMETLVRDKGVNSFQMYMAYKDMYMLRDSELFQALQNCKDIGAVARVHAENGELVAEGAREALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLASAKMQGKVVHGETTTAHAVLNGMQYYHQDWAHAAAFVTVPPLRLDPNTPNYLLSLLGNDTLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSVMWERGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPESTRTISVTTQWQGGDVNLYENLRCHGVPLVTISRGRVVYENGIFTCAEGSGKFYPLRTFPDYLYKKMVQREKCQAL--KGVER-----TPYTGDVAAVQNSGK---KDLGPADGDMNP----RPCTRHGGVRDLHESSFSLSGAQIDDNVPKRASARILAPPGGRSSGIW 564          
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl4 (dihydropyrimidinase like 4 [Source:ZFIN;Acc:ZDB-GENE-050720-3])

HSP 1 Score: 306.22 bits (783), Expect = 1.094e-95
Identity = 195/572 (34.09%), Postives = 309/572 (54.02%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPST-----NFNLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNP-HKVIQ--KDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            K+++KGG IVN D+ F +D+ +E+ IIKQIG++++V    K +D    ++IPGGID +T     +  +SP   D  ++ + AALAGGTT II  V  + G+ L+++    +     +  C+Y   + I    D   + +E+L +  G+N F + +  +    +++T          +     +VH  +   +E  +++L+  GI+GPEG   S   E E E +YR + +     C L I +VM++  A L+AK + +G  I+ E I  +L      Y+S NW E+A+ +  PP+  D      +   + CGD+ + AS + T T A +++GK DF  IP G +G+EER+S++WD+ V +G ++E +FV+ TSTNAAKIFNLYP +G IAVGS ADIVIWN  +TRT SA + +L  + NIFEG+ C+G P +VI  G +  +     +   +G  I  K     V      Y+ ++   +M   R +             + P H VI   K +    +   P    + P  G  RN+  S F+LSG+Q+DD  P R+  +   PPGG+SN+
Sbjct:   16 KLIIKGGKIVNDDQSFYADIYVEDGIIKQIGENLIVPTGVKTVDAYGHIVIPGGIDVNTCLQAPHLGMSP--ADDFYHGTRAALAGGTTMIIDHVVPEPGSSLLSAFDQWKDTADKRSCCDYSLHIDITRWHDGLFEELESLVKDKGVNSFLIFMAYKDKFQSSDTQIYEMFSAMRELGAIAQVHAENGDIIEEEQKKLLDLGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSKPAADLIAKARKKGMVIYGEPIAASLGTDGSHYWSKNWAEAAAFVMSPPLNPDTSTPDYLNSLLSCGDLQVTASANCTFTTAQKAVGKDDFTFIPEGTNGIEERMSIVWDKAVATGKMDENDFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWNTKETRTFSAKTHNLTVEVNIFEGMECRGFPVLVISQGRIVLEDGTLSVMEGSGRFIPRKAYPDYV------YKRIKARSRMADARGVPRG--------NYDGPVHDVISMTKSVPATPTTRGPSCPGKTPL-GPTRNLHQSGFTLSGTQMDDHIPRRTAQKIVAPPGGRSNI 570          
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl5a (dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-GENE-030131-3136])

HSP 1 Score: 305.449 bits (781), Expect = 2.111e-95
Identity = 194/584 (33.22%), Postives = 309/584 (52.91%), Query Frame = 1
Query:   28 TMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIG-----------------NEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPT-SGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            T+++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL++PGGID S + N   ++    D  ++ + AALAGGTT +I  V  +    L+++ +  +S   +K  C+Y   + +     +    METL R  G+N FQM +                  N  +   V+ +              H   +      E +  GISGPEG   SR  E E E ++R + + +   C + +  V +     ++A  KM+G+ +  ET      L+  +Y+  +W  +A+ +T PP+R D +    ++  +    +++V S+H   T   +++GK DF  IPHGV GV++R+S++W+RGV  G ++E  FV+ TS+NAAKI+NLYP +G I  G+ AD+V+W+P  TRTIS  +Q    D N++E + C GVP V I  G V ++   F     +G+   L+     +  KM + E  +     G+ R          ++  + N  K   KD+   D  +NP    RP T  GG R++ +SSFSLSG+QIDD  P R++ R   PPGG+S+ I+
Sbjct:    7 TVRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLNESFMNGTTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKARSHADAKACCDYALHMGVTWWGPKARAQMETLVRDKGVNSFQMYMAYKDMYMLRDSELFQALQNCKDIGAVARVHAENGELVAESSLSHVFIFTHKGAREALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLASAKMQGKVVHGETTTAHAVLNGMQYYHQDWAHAAAFVTVPPLRLDPNTPNYLLSLLGNDTLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSVMWERGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPESTRTISVTTQWQGGDVNLYENLRCHGVPLVTISRGRVVYENGIFTCAEGSGKFYPLRTFPDYLYKKMVQREKCQAL--KGVER-----TPYTGDVAAVQNSGK---KDLGPADGDMNP----RPCTRHGGVRDLHESSFSLSGAQIDDNVPKRASARILAPPGGRSSGIW 576          
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: crmp1 (collapsin response mediator protein 1 [Source:ZFIN;Acc:ZDB-GENE-050720-1])

HSP 1 Score: 305.449 bits (781), Expect = 2.310e-95
Identity = 205/575 (35.65%), Postives = 311/575 (54.09%), Query Frame = 1
Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKS-METLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            I +  + ++L+KGG +VN D+   +DV +E+ IIKQ+G++++V G  KVI+    ++IPGGID +T  +   L     D  +  + AALAGGTT II  V  Q G  L+ + +  Q     K  C+Y   V I P+  E VK  +E L ++ GIN FQ+ +  +      ++         KEL  ++ +   +   +   + +++  GI GPEG   SR  E E E ++R + + +   C + I +VM++  A+ VA  + +G  +F E I  +LA     Y+S NW ++A+ +T PP+  D      +   + CGD+ +V S H   + + ++IGK +F  IP G +GVEER+  +WD+ V  G ++E +FV+ TSTNAAKIFNLYP +G IAVGS ADIVIW+P K +TI+A SQ    + NIFEG+ C+G P  V+  G V F+  +  +   TG  I  K        ++K    +      G++R + D       +  +    K I        +K +P   Q PP     RN+  S+FSLSGSQIDD  P RS  R   PPGG+SN+
Sbjct:   12 IPHLTSERLLIKGGRVVNDDQSLYADVYVEDGIIKQVGENLIVPGGVKVIEANGCMVIPGGIDVNTCLHKPYLGTPPVDDFYQGTKAALAGGTTMIIDHVTPQPGDGLLEAFEKWQEAADKKSCCDYSLHVDI-PHWHEGVKEELEQLVQEKGINSFQVYMAYKGLYQMPDSQLYEAFSFLKELGAVVLVHAENGDLIAQEQSKILGMGIIGPEGHPLSRPEELEAEAVFRAITIGNRVNCPVYITKVMSKSAAETVAIARKKGSVVFGEPITASLATDGSHYWSKNWAKAAAYVTSPPLSPDPTTPEHLHSLLACGDLQVVGSGHCAYSTSQKAIGKDNFTLIPEGTNGVEERMGFVWDKAVAMGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPDKIKTITAKSQQSALEYNIFEGMDCRGGPLHVVSQGRVVFEEGKLQVQQGTGRFISRKPFPDFAYQRIKYRNKIMNM--QGVSRGMYDG-----PVYDVPATPKYITP---APSAKTSPTTHQPPPI----RNLHQSNFSLSGSQIDDNIPRRSGHRIVAPPGGRSNI 571          
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482])

HSP 1 Score: 306.22 bits (783), Expect = 1.461e-95
Identity = 195/568 (34.33%), Postives = 302/568 (53.17%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKIN-PLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ IE+ +IKQIG++++V G  K ID    L+IPGGID  T   +        D     + AALAGGTT II  V   SG  LV +    +     KV C+Y   + I    +   + +E L +  G+N F + +  +      +A    +    ++L  + ++   +   ++  ++ ++  GI+GPEG   S   E E E  YR + +     C L I +VM+   A ++A+ K +G  ++ ET+  ++      Y+S NW ++A+ +T PPI  D      +   + CGD+ +  S H T T A +++GK +F  IP G +G+EER++++WD+ V SG ++E  FV+ TSTNAAK+FNLYP +G IA GS AD+VIWNP   + ISA + ++  + NIFEG+ C G PEVVI  G +  +  N  +   +G  +  K     V  ++K    L E    G+ R + D          +++     +    T  S+I  P K+Q  P     RN+  S FSLSGSQ DD  P R+T +   PPGG+SN+
Sbjct:   13 RLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCTDAEMYEIFSIIRDLGAIAQVHAENGDIIQEEQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRKGIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLLSCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNVELNIFEGMECHGAPEVVISQGRIVLEDGNLHVSQGSGRFVPRKTFPDYVYKRIKARNRLAEI--RGVPRGLYDG--------PVHDVTITTKSAASTPASRIACPGKIQMGPV----RNLHHSGFSLSGSQEDDHVPRRTTQKIVAPPGGRSNI 566          
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482])

HSP 1 Score: 306.605 bits (784), Expect = 1.478e-95
Identity = 197/576 (34.20%), Postives = 306/576 (53.12%), Query Frame = 1
Query:   10 YILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKIN-PLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            YI+ +   ++L+KGG IVN D+ F +D+ IE+ +IKQIG++++V G  K ID    L+IPGGID  T   +        D     + AALAGGTT II  V   SG  LV +    +     KV C+Y   + I    +   + +E L +  G+N F + +  +      +A    +    ++L  + ++   +   ++  ++ ++  GI+GPEG   S   E E E  YR + +     C L I +VM+   A ++A+ K +G  ++ ET+  ++      Y+S NW ++A+ +T PPI  D      +   + CGD+ +  S H T T A +++GK +F  IP G +G+EER++++WD+ V SG ++E  FV+ TSTNAAK+FNLYP +G IA GS AD+VIWNP   + ISA + ++  + NIFEG+ C G PEVVI  G +  +  N  +   +G  +  K     V  ++K    L E    G+ R + D          +++     +    T  S+I  P K+Q  P     RN+  S FSLSGSQ DD  P R+T +   PPGG+SN+
Sbjct:   27 YIVTYD--RLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCTDAEMYEIFSIIRDLGAIAQVHAENGDIIQEEQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRKGIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLLSCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNVELNIFEGMECHGAPEVVISQGRIVLEDGNLHVSQGSGRFVPRKTFPDYVYKRIKARNRLAEI--RGVPRGLYDG--------PVHDVTITTKSAASTPASRIACPGKIQMGPV----RNLHHSGFSLSGSQEDDHVPRRTTQKIVAPPGGRSNI 586          
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482])

HSP 1 Score: 305.834 bits (782), Expect = 1.639e-95
Identity = 195/568 (34.33%), Postives = 302/568 (53.17%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKIN-PLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ IE+ +IKQIG++++V G  K ID    L+IPGGID  T   +        D     + AALAGGTT II  V   SG  LV +    +     KV C+Y   + I    +   + +E L +  G+N F + +  +      +A    +    ++L  + ++   +   ++  ++ ++  GI+GPEG   S   E E E  YR + +     C L I +VM+   A ++A+ K +G  ++ ET+  ++      Y+S NW ++A+ +T PPI  D      +   + CGD+ +  S H T T A +++GK +F  IP G +G+EER++++WD+ V SG ++E  FV+ TSTNAAK+FNLYP +G IA GS AD+VIWNP   + ISA + ++  + NIFEG+ C G PEVVI  G +  +  N  +   +G  +  K     V  ++K    L E    G+ R + D          +++     +    T  S+I  P K+Q  P     RN+  S FSLSGSQ DD  P R+T +   PPGG+SN+
Sbjct:    7 RLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCTDAEMYEIFSIIRDLGAIAQVHAENGDIIQEEQKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRKGIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLLSCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNVELNIFEGMECHGAPEVVISQGRIVLEDGNLHVSQGSGRFVPRKTFPDYVYKRIKARNRLAEI--RGVPRGLYDG--------PVHDVTITTKSAASTPASRIACPGKIQMGPV----RNLHHSGFSLSGSQEDDHVPRRTTQKIVAPPGGRSNI 560          
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:548482])

HSP 1 Score: 306.22 bits (783), Expect = 2.533e-95
Identity = 196/576 (34.03%), Postives = 306/576 (53.12%), Query Frame = 1
Query:   10 YILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKIN-PLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++  +K  ++L+KGG IVN D+ F +D+ IE+ +IKQIG++++V G  K ID    L+IPGGID  T   +        D     + AALAGGTT II  V   SG  LV +    +     KV C+Y   + I    +   + +E L +  G+N F + +  +      +A    +    ++L  + ++   +   ++  ++ ++  GI+GPEG   S   E E E  YR + +     C L I +VM+   A ++A+ K +G  ++ ET+  ++      Y+S NW ++A+ +T PPI  D      +   + CGD+ +  S H T T A +++GK +F  IP G +G+EER++++WD+ V SG ++E  FV+ TSTNAAK+FNLYP +G IA GS AD+VIWNP   + ISA + ++  + NIFEG+ C G PEVVI  G +  +  N  +   +G  +  K     V  ++K    L E    G+ R + D          +++     +    T  S+I  P K+Q  P     RN+  S FSLSGSQ DD  P R+T +   PPGG+SN+
Sbjct:   30 WVCTYKDDRLLIKGGKIVNDDQSFLADIYIEDGLIKQIGENLIVPGGVKTIDAHGLLVIPGGIDVHTRLQMPVMGMTSADDFFQGTKAALAGGTTMIIDHVFPDSGMNLVQAYDQWREWADGKVCCDYSLHIDITYWHESLKEELEALVKDKGVNSFLVFMAYKDQYQCTDAEMYEIFSIIRDLGAIAQVHAENGDIIQE-QKRMLECGITGPEGHVLSHPEEVEAEAAYRAITIAKQANCPLYITKVMSRGAADVIAQAKRKGIVVYGETLTASIGTDGTHYWSKNWAKAAAYVTSPPISPDPSTPDHLTSLLSCGDLHVTGSAHCTFTTAQKAVGKDNFILIPEGTNGIEERMTIIWDKCVTSGKMDENAFVAVTSTNAAKLFNLYPRKGRIATGSDADLVIWNPKTAKIISAKTHNMNVELNIFEGMECHGAPEVVISQGRIVLEDGNLHVSQGSGRFVPRKTFPDYVYKRIKARNRLAEI--RGVPRGLYDG--------PVHDVTITTKSAASTPASRIACPGKIQMGPV----RNLHHSGFSLSGSQEDDHVPRRTTQKIVAPPGGRSNI 590          
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: bco2 (beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-GENE-5747659])

HSP 1 Score: 303.908 bits (777), Expect = 2.019e-94
Identity = 201/577 (34.84%), Postives = 310/577 (53.73%), Query Frame = 1
Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPN---HRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNAT---GERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
             L F++ ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+   +++IPGGID  T F    N     D     + AALAGGTT II  V  + G+ L+++    +    +K  C+Y   V I        + ME L +  G+N F + +  +      ++    V    +++  + ++   +   +   +  ++  GI+GPEG   SR  E E E   R + + +   C L + +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WDR V SG ++E +FV+ TSTNAAKIFNLYP +G IAVGS AD+VIW+P   RTISA + +   + NIFEG+ C+G P VVI  G  K  L E   +AT   G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K    P     RN+  S FSLSG+Q+DD  P R+T R   PPGG++N+
Sbjct:   40 FLIFQSDRLLIKGGKIVNDDQSFHADIYMEDGLIKQIGENLIVPGGVKTIEAHGRMVIPGGIDVHTCFQKPCNGMVSSDDFFQGTKAALAGGTTMIIDHVVPEPGSSLLSAFDQWREWADTKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAYKDQYQLTDSQIYEVFSVIRDIGAIAEVHAENGDVIAEEQLRILEQGINGPEGHVLSRPEEVEAEAANRSITIANQTNCPLYVTKVMSKSSAEVIAQARKKGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPSTPDFLNSLLSCGDLQVCGSSHCTFNTAQKAVGKDNFTLIPEGTNGAEERMSVVWDRAVVSGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWDPDSVRTISAKTHNSNVEYNIFEGMECRGSPLVVISQG--KIVLEEGTLHATEGSGRYIPRKPFPDYVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKAVTPASSAKTSPAKQPAQPI----RNLHQSGFSLSGAQVDDNIPRRTTQRIVAPPGGRANI 599          
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl2 (dihydropyrimidinase-like 2 [Source:MGI Symbol;Acc:MGI:1349763])

HSP 1 Score: 307.375 bits (786), Expect = 3.793e-96
Identity = 194/569 (34.09%), Postives = 310/569 (54.48%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+  ++++IPGGID  T F + P+      D     + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + ME L +  G+N F + +  +      ++    VL   +++  + ++   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L + +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAK+FNLYP +G I+VGS AD+VIW+P   +TISA + +   + NIFEG+ C+G P VVI  G +  +     +   +G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K Q PP     RN+  S FSLSG+QIDD  P R+T R   PPGG++N+
Sbjct:   16 RLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQM-PDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTVTPASSAKTSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANI 568          
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl4 (dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:MGI:1349764])

HSP 1 Score: 306.99 bits (785), Expect = 5.326e-96
Identity = 197/567 (34.74%), Postives = 298/567 (52.56%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K ID    +++PGG+D  T   +        D     + AALAGGTT I+  V   +G  L+ + +  +    S   C+Y   V I    +   + +E L R  G+N F + +  +      +     +    ++L  + ++   +   +E  ++ L+  GI+GPEG   S   E E E +YR + +     C L + +VM++  A +VA+ K  G  +F E I  +L      Y+S NW ++A+ +T PPI  D   A  +   +  GD+ +  S H T T A +++GK +F  IP GV+G+EER+S++W++ V SG ++E EFV+ TSTNAAKIFN YP +G +AVGS AD+VIWNP  T+ ISA S +L  + NIFEG+ C+GVP VVI  G V  +  N  +    G  I  K     V  ++K    L E    G+ R + D  G   E+     P    Q             K+  PP     RN+  S FSLSGSQ DD    R+  +   PPGG+SN+
Sbjct:   16 RLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYD--GPVHEVMLPAKPGSGTQARASCSG------KISVPPV----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNI 568          
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl4 (dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:MGI:1349764])

HSP 1 Score: 306.99 bits (785), Expect = 5.326e-96
Identity = 197/567 (34.74%), Postives = 298/567 (52.56%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K ID    +++PGG+D  T   +        D     + AALAGGTT I+  V   +G  L+ + +  +    S   C+Y   V I    +   + +E L R  G+N F + +  +      +     +    ++L  + ++   +   +E  ++ L+  GI+GPEG   S   E E E +YR + +     C L + +VM++  A +VA+ K  G  +F E I  +L      Y+S NW ++A+ +T PPI  D   A  +   +  GD+ +  S H T T A +++GK +F  IP GV+G+EER+S++W++ V SG ++E EFV+ TSTNAAKIFN YP +G +AVGS AD+VIWNP  T+ ISA S +L  + NIFEG+ C+GVP VVI  G V  +  N  +    G  I  K     V  ++K    L E    G+ R + D  G   E+     P    Q             K+  PP     RN+  S FSLSGSQ DD    R+  +   PPGG+SN+
Sbjct:   16 RLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYD--GPVHEVMLPAKPGSGTQARASCSG------KISVPPV----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNI 568          
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl4 (dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:MGI:1349764])

HSP 1 Score: 306.99 bits (785), Expect = 1.033e-95
Identity = 197/567 (34.74%), Postives = 298/567 (52.56%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K ID    +++PGG+D  T   +        D     + AALAGGTT I+  V   +G  L+ + +  +    S   C+Y   V I    +   + +E L R  G+N F + +  +      +     +    ++L  + ++   +   +E  ++ L+  GI+GPEG   S   E E E +YR + +     C L + +VM++  A +VA+ K  G  +F E I  +L      Y+S NW ++A+ +T PPI  D   A  +   +  GD+ +  S H T T A +++GK +F  IP GV+G+EER+S++W++ V SG ++E EFV+ TSTNAAKIFN YP +G +AVGS AD+VIWNP  T+ ISA S +L  + NIFEG+ C+GVP VVI  G V  +  N  +    G  I  K     V  ++K    L E    G+ R + D  G   E+     P    Q             K+  PP     RN+  S FSLSGSQ DD    R+  +   PPGG+SN+
Sbjct:   37 RLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYD--GPVHEVMLPAKPGSGTQARASCSG------KISVPPV----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNI 589          
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl4 (dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:MGI:1349764])

HSP 1 Score: 306.99 bits (785), Expect = 1.033e-95
Identity = 197/567 (34.74%), Postives = 298/567 (52.56%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K ID    +++PGG+D  T   +        D     + AALAGGTT I+  V   +G  L+ + +  +    S   C+Y   V I    +   + +E L R  G+N F + +  +      +     +    ++L  + ++   +   +E  ++ L+  GI+GPEG   S   E E E +YR + +     C L + +VM++  A +VA+ K  G  +F E I  +L      Y+S NW ++A+ +T PPI  D   A  +   +  GD+ +  S H T T A +++GK +F  IP GV+G+EER+S++W++ V SG ++E EFV+ TSTNAAKIFN YP +G +AVGS AD+VIWNP  T+ ISA S +L  + NIFEG+ C+GVP VVI  G V  +  N  +    G  I  K     V  ++K    L E    G+ R + D  G   E+     P    Q             K+  PP     RN+  S FSLSGSQ DD    R+  +   PPGG+SN+
Sbjct:   37 RLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYD--GPVHEVMLPAKPGSGTQARASCSG------KISVPPV----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNI 589          
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q90635|DPYL2_CHICK (Dihydropyrimidinase-related protein 2 OS=Gallus gallus OX=9031 GN=DPYSL2 PE=2 SV=1)

HSP 1 Score: 313.153 bits (801), Expect = 1.574e-97
Identity = 197/568 (34.68%), Postives = 308/568 (54.23%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSP---NHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+   +++IPGGID  T F +        D     + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + ME L +  G+N F + +  +      ++    VL   +++    ++   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAKIFNLYP +G IAVGS AD+VIW+P   +TISA + ++  + NIFEG+ C+G P VVI  G +  +  N  +   +G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K Q PP     RN+  S FSLSG+QIDD  P R+T R   PPGG++N+
Sbjct:   16 RLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHGRMVIPGGIDVHTRFQMPEQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLTAFDQWREWADSKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAFKDRFQLSDSQIYEVLSVIRDIGATAQVHAENGDIIAEEQQRILELGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSIIWDKAVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNISLEYNIFEGMECRGSPLVVISQGKIVLEDGNLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTVTPASSAKTSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANI 568          
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q9BPU6|DPYL5_HUMAN (Dihydropyrimidinase-related protein 5 OS=Homo sapiens OX=9606 GN=DPYSL5 PE=1 SV=1)

HSP 1 Score: 309.301 bits (791), Expect = 3.595e-96
Identity = 200/579 (34.54%), Postives = 319/579 (55.09%), Query Frame = 1
Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAI-IRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKM-KRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVT--VDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            + N  ++++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL+IPGGID ST+F+   ++    D  ++ + AAL GGTT II  V       LV++ +  +     KV C+Y   V I     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GI+GPEG   SR  E E E  +R++ + +   C + +  V +     ++A  KM+G+ + +ET      L+   Y+  +W  +A+ +T PP+R D + +  + S+   D +++VAS+H   T   +++GK DF  IPHGVSGV++R+S++W+RGV  G ++E  FV+ TS+NAAK+ NLYP +G I  G+ AD+V+W+P  T+TISA +Q    D N++E + C GVP V I  G V ++   F+    TG+   L+     V  K+ +R + L+  G         D      ++  + +P K   K++ T   D+   P+        GG R++ +SSFSLSGSQIDD  P R++ R   PPGG+S+ I+
Sbjct:    2 LANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRG--------VDRTPYLGDVAVVVHPGK---KEMGTPLADTPTRPVTRH-----GGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564          
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|O02675|DPYL2_BOVIN (Dihydropyrimidinase-related protein 2 OS=Bos taurus OX=9913 GN=DPYSL2 PE=1 SV=1)

HSP 1 Score: 309.686 bits (792), Expect = 3.686e-96
Identity = 196/569 (34.45%), Postives = 310/569 (54.48%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRS--IHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K I+  ++++IPGGID  T F + P+      D     + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + ME L +  G+N F + +  +      ++    VL   +++  + ++   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  A+++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D       +  + CGD+ +  S H T   A +++GK +F  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAK+FNLYP +G IAVGS AD+VIW+P   +TISA + +   + NIFEG+ C+G P VVI  G +  +     +   +G  I  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K Q PP     RN+  S FSLSG+QIDD  P R+T R   PPGG++N+
Sbjct:   16 RLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQM-PDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYITKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTVTPASSAKTSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANI 568          
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q62951|DPYL4_RAT (Dihydropyrimidinase-related protein 4 (Fragment) OS=Rattus norvegicus OX=10116 GN=Dpysl4 PE=1 SV=1)

HSP 1 Score: 308.916 bits (790), Expect = 4.789e-96
Identity = 198/567 (34.92%), Postives = 299/567 (52.73%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KGG IVN D+ F +D+ +E+ +IKQIG++++V G  K ID    +++PGG+D  T      L     D     + AALAGGTT I+  V   +G  L+ + +  +    S   C+Y   V I    +   + +E L R  G+N F + +  +      +     +    ++L  + ++   +   +E  ++ L+  GI+GPEG   S   E E E +YR + +     C L I +VM++  A +VA+ K  G  +F E I  +L      Y+S NW ++A+ +T PPI  D   A  +   +  GD+ +  S H T T A +++GK +F  IP G++G+EER+S++W++ V SG ++E EFV+ TSTNAAKIFN YP +G +AVGS AD+VIWNP  T+ ISA S +L  + NIFEG+ C+G+P VVI  G V  +  N  +    G  I  K     V  ++K    L E    G+ R + D  G   E+     P    Q           P K+  PP     RN+  S FSLSGSQ DD    R+  +   PPGG+SN+
Sbjct:    8 RLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYITKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGINGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGMPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYD--GPVHEVMLPAKPGSGTQARASC------PGKISVPPV----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNI 560          
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q9JHU0|DPYL5_RAT (Dihydropyrimidinase-related protein 5 OS=Rattus norvegicus OX=10116 GN=Dpysl5 PE=1 SV=1)

HSP 1 Score: 308.531 bits (789), Expect = 7.401e-96
Identity = 201/579 (34.72%), Postives = 319/579 (55.09%), Query Frame = 1
Query:   13 ILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA-IIRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKM-KRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVT--VDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            + N  ++++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL+IPGGID ST+F+   ++    D  ++ + AAL GGTT II  V       LV + +  ++    KV C+Y   V I     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GI+GPEG   S   E E E  +R++ + +   C + +  V +     ++A  KM+G+ + +ET      L+   Y+  +W  +A+ +T PP+R D + +  + S+   D +++VAS+H   T   +++GK DF  IPHGVSGV++R+S++W+RGV  G ++E  FV+ TS+NAAKI NLYP +G I  G+ AD+V+W+P  T+TISA +Q    D N++E + C GVP V I  G V ++   F+    TG+   L+    +V  K+ +R + L+  G         D      ++  + NP K   K++ T   D+   P+        GG R++ +SSFSLSGSQIDD  P R++ R   PPGG+S+ I+
Sbjct:    2 LANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVFHACRDFGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKTLKVRG--------VDRTPYLGDVAVVVNPGK---KEMGTPLADTPTRPVTRH-----GGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564          
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: K1PGY5 (Dihydropyrimidinase OS=Crassostrea gigas OX=29159 GN=CGI_10005185 PE=4 SV=1)

HSP 1 Score: 345.51 bits (885), Expect = 1.497e-106
Identity = 213/571 (37.30%), Postives = 324/571 (56.74%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVE-EELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQD--AAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKV--IQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            ++L+KGG IVN D+ F +D+ IE+ IIKQ+G ++V+ G  + I+   KL++PGGID  T+  L        D  ++ + AALAGGTT II  V +Q G  L+ +    +     KV C+YG  V +    D+  K METL  + GIN F+M +  +    +N + +    K  +    L +   ++ +L A + +E++  GISGPEG    R  E E E   R + + +   C L I  VM++  A +V+K + EG+ +F E I  +L      Y++  W  +A  +  PP+R D      ++  +   D+ +  +++ T +   +++GK DFR IP+GV+GVE+R+S++W++GV SG ++ C FV+ TSTNAAKIFN+YP +G IAVGS ADIVIW+P ++RTISA + H   D NIFEG+ C GVP  VI NG V     +  +    G  I    N ++V  ++ +    RE  +M    E     G    +  I N  +V  +++D   +          RPPT GG RN+QDSSF+LSG Q DD+ P R+ IRT++PPGGKS+ ++
Sbjct:   84 RLLIKGGKIVNDDQSFDADIYIEDGIIKQVGTNLVIPGGARTIEARGKLVMPGGIDTHTHMQLPFMGTYAVDDFYSGTKAALAGGTTMIIDFVLDQKGVSLLEAYDKWRGWADPKVCCDYGLHVGVTWWSDQVAKEMETLCAEKGINSFKMFLAYKDVFMLNDDELYESFKRIKELGALGMVHAENGHLIAEKSKEMLKMGISGPEGHEMCRPEEVEAEATQRAITIANQANCPLYIVHVMSKSSADVVSKARREGKVVFGEPIAASLGTDGTHYWNKCWRHAAGHVMGPPLRPDSSTPGYLMDLLANNDLQVTGTDNCTFSADQKALGKDDFRKIPNGVNGVEDRMSVIWEKGVHSGKMDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWDPKESRTISAKTHHQAVDFNIFEGMVCHGVPVYVITNGHVVLDEGQLKVTQGMGRFIPTPCNAEMVYGRVAK----RELARMPQKVERDPYTG---PVVKIENQDEVPGVKRDENPIVGDTASFAHSRPPTRGGGRNLQDSSFALSGEQFDDKAPRRAQIRTSNPPGGKSSGLW 647          
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A1W7RAR0 (Dihydropyrimidinase OS=Hadrurus spadix OX=141984 PE=4 SV=1)

HSP 1 Score: 340.502 bits (872), Expect = 1.795e-105
Identity = 205/581 (35.28%), Postives = 323/581 (55.59%), Query Frame = 1
Query:   16 LNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRND--QDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERI------DLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            L     ++L+KGG +VN D  F +DV +E+ IIKQ+G+ +++ G T+ I+   K ++PGGIDP T+F    LS    D  +N + AALAGGTT I+  V +     L+ + +  +S    KV C+Y   + I    D   + M+ L ++ GIN F   +  +      +   + V     +L  L ++   +   +  +EE ++  GI+GPEG+  +R  E E E   R + L +   C L +  VM++  A ++++ + EG  ++ E I  ALA     YF+  W  +A+ +  PP+R D    + ++  ++CGD+ + AS ++T   + +++G  DF  IP GV+GVE+R+S++W+RGV SG I+ C FV+ TSTNAAKIFN+YP +G I VGS ADIV+W+P +TRTIS+ + H   D NIFE ++C GVPE VI  G V  +  E  +    G  I          NC + ++K ++         + + RE      V  E+  + +  +V  ++ V +          RPPT  G RN+QDS+FSLSG+QIDD K  R+ I+ N+PPGG+S  ++
Sbjct:   12 LQSAQTRLLIKGGKVVNDDLIFDADVYVEDGIIKQVGRDLIIPGGTRTIEAKGKFVMPGGIDPHTHFEFPFLSVKSADDFYNGTKAALAGGTTMIMDFVVDPD-CSLLEAYEKWRSVADEKVCCDYNLHIGITSWSDNIEQEMDILTKEKGINSFMTFMAYKDVLMLRDDELLKVFDISSKLGALAQVHAENGDIIHELEERILALGITGPEGYVYTRPEEIEAEATQRAITLANQMNCPLYVVHVMSKSAADVISRKRKEGCIVYGEAIAAALATDGTHYFNQCWGHAAAHVMSPPLRPDPRTPSYLMDYLNCGDLAVTASANSTFNTSQKALGAEDFTKIPPGVNGVEDRMSVIWERGVVSGKIDPCRFVAVTSTNAAKIFNIYPRKGRIQVGSDADIVVWDPYRTRTISSKTHHHSVDFNIFEDMTCHGVPEYVIAQGRVVLEEGELHVCQGMGRFIPASPFSPFVFNCIMEREKARQ--------PIKVNREAYTG-PVKEEVAYLTDGTQVPYRETVIMSQSSKEFH-SRPPTRSGGRNLQDSTFSLSGAQIDDNKSPRAGIKINNPPGGRSTGLW 581          
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A267FG46 (Amidohydro-rel domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032114g1 PE=4 SV=1)

HSP 1 Score: 334.724 bits (857), Expect = 5.373e-103
Identity = 201/571 (35.20%), Postives = 312/571 (54.64%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQ--MTIGNEI---NANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRN-DQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLK------MQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSN 1698
            ++L+KGG +VN D   ++DV +E  +IKQ+G  ++  G  +VID    LI+PGGIDP T+  +     +  D  +  + AALAGGTT II  V    G  L++     ++    KV C+YG  V +    D+    M TL ++ GIN F+  M   N     +   ++V + C++L  + ++   +   +E   E+L+  GI GPEG   SR    E+E   R L +     C L +  VM+ +  + ++K +  G+  + E I   LA  +  Y    W  +A  +  PP+R+      + R +  G++    ++H       +++GK DFR IP+GV+GVE+R+S+LW++GV++GI++ C+FV+ATSTNAAK+FNLYP +G IAVGS ADIV+WN  +TRTISA + H   D NIFEG+ C G+ E VI  G +     +  +    G  + +      V +++++ E  +  G + + R+  D  G   +++      K + K+           +        RPPT GG R+MQ+SSFSLSG+Q DD KP RS IRT+ PPGG S+
Sbjct:   23 RLLIKGGKVVNDDGIQEADVYVEGGVIKQVGTGLLTPGGVRVIDAAGMLIMPGGIDPHTHMQMPFMGTHSADDFYTGTRAALAGGTTMIIDFVACPRGDSLMDWYNKYRAWADEKVCCDYGLHVIVPQWGDKTANEMATLVKEKGINSFKCFMAYRNVFLLEDDEMLNVFQACRKLGAVAQVHAENGKIIERKAEQLVADGIRGPEGHSYSRPEAMEIEATTRALAIADEANCPLYVVHVMSAEAGEAISKARRRGQVCYGEPIAAGLACDNSSYQHTCWRHAAGHVLSPPLRDPSTKERLWRMLATGELTCTGTDHCVFKADQKALGKDDFRRIPNGVNGVEDRMSVLWEKGVETGILDPCQFVAATSTNAAKVFNLYPQKGRIAVGSDADIVVWNAKETRTISAKTHHQNVDFNIFEGMVCHGIAEFVISGGRLVVDERQLKVTQGAGRFVPMPAFPPYVYNRLEKREAAKSAGTVAVARDAYD--GPVIDLKAEQERQKAVAKEQPGAAGGGGGPEAAAENVFHRPPTRGGGRHMQESSFSLSGAQFDDTKPARSGIRTHQPPGGASS 591          
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A183TGQ2 (Dihydropyrimidinase OS=Schistocephalus solidus OX=70667 PE=4 SV=1)

HSP 1 Score: 333.569 bits (854), Expect = 9.600e-103
Identity = 206/574 (35.89%), Postives = 318/574 (55.40%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTI---GNEINANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITRE-----ISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            ++ LKGG +VN DRKF +D+ IE+ +IKQ+G ++ + G  + +DV  KL++PGGID  T+  +     +  D  ++ + AALAGGTT II  V    G+ ++ + +  +    SKV C+Y   V +   +++    ME L ++ GIN F+  +   G  +  +       C+  +     +VH  +   +   +EE+I  GI GPEG   SR    E+E   R + L     C L +  VM+   A  +A+ + +G  +  E +   L      Y    W  +A  +  PP+R + +    +++++  G ++   ++H       +++GK DFR IP+GV+GVE+R+S++W++GV SGII+ C+FV+ TSTNAAKIFN+YP +G I VGS ADIV+W+P   RTISA + H   D NIFEG+ C GVP +VI NG V  + ++  +   TG  +        V  K++  + LRE  ++ + RE     ++D +G A +   I       + D      +      QRPPTS G RNMQDSSF+LSGSQ+DD  P+RSTIRT  PPGG S  ++
Sbjct:   25 RLHLKGGTVVNDDRKFVADIYIEDGVIKQVGTNLSIPGGVRTVDVRGKLVMPGGIDTHTHMEMPFMGTHSSDDFYSGTKAALAGGTTMIIDFVCPARGSSILEAYEQYREKADSKVCCDYALHVIVPHFDEKLSNEMEVLTKEKGINSFKSFLAYPGVFMLEDDELYDFFCRCRELGALAQVHAENGKLISRKQEEVIQHGILGPEGHPFSRPEAAEVEATSRAITLADTANCPLYVVHVMSALAANKIAEARQDGILVIGEAVAAGLGTDGSHYLDKCWRSAAGYVMSPPLRMNPETPRLLMKALANGHLECTGTDHCVFKADQKALGKDDFRKIPNGVNGVEDRMSVIWEKGVVSGIIDPCKFVAITSTNAAKIFNIYPRKGRIEVGSDADIVVWDPEAERTISASTHHQNVDFNIFEGMRCHGVPLIVITNGHVVLEDDDLKVSQGTGRFVPTPPFSPYVYAKIEGRQKLRE--RIPVAREPYTGPVAD-LGAALQATDIKTVFANGKGD------QAQAFNRQRPPTSAGGRNMQDSSFALSGSQVDDALPVRSTIRTQQPPGGASRSLW 589          
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A3P7D5Z0 (Amidohydro-rel domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS15650 PE=4 SV=1)

HSP 1 Score: 333.569 bits (854), Expect = 9.911e-103
Identity = 206/574 (35.89%), Postives = 318/574 (55.40%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTI---GNEINANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITRE-----ISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            ++ LKGG +VN DRKF +D+ IE+ +IKQ+G ++ + G  + +DV  KL++PGGID  T+  +     +  D  ++ + AALAGGTT II  V    G+ ++ + +  +    SKV C+Y   V +   +++    ME L ++ GIN F+  +   G  +  +       C+  +     +VH  +   +   +EE+I  GI GPEG   SR    E+E   R + L     C L +  VM+   A  +A+ + +G  +  E +   L      Y    W  +A  +  PP+R + +    +++++  G ++   ++H       +++GK DFR IP+GV+GVE+R+S++W++GV SGII+ C+FV+ TSTNAAKIFN+YP +G I VGS ADIV+W+P   RTISA + H   D NIFEG+ C GVP +VI NG V  + ++  +   TG  +        V  K++  + LRE  ++ + RE     ++D +G A +   I       + D      +      QRPPTS G RNMQDSSF+LSGSQ+DD  P+RSTIRT  PPGG S  ++
Sbjct:   25 RLHLKGGTVVNDDRKFVADIYIEDGVIKQVGTNLSIPGGVRTVDVRGKLVMPGGIDTHTHMEMPFMGTHSSDDFYSGTKAALAGGTTMIIDFVCPARGSSILEAYEQYREKADSKVCCDYALHVIVPHFDEKLSNEMEVLTKEKGINSFKSFLAYPGVFMLEDDELYDFFCRCRELGALAQVHAENGKLISRKQEEVIQHGILGPEGHPFSRPEAAEVEATSRAITLADTANCPLYVVHVMSALAANKIAEARQDGILVIGEAVAAGLGTDGSHYLDKCWRSAAGYVMSPPLRMNPETPRLLMKALANGHLECTGTDHCVFKADQKALGKDDFRKIPNGVNGVEDRMSVIWEKGVVSGIIDPCKFVAITSTNAAKIFNIYPRKGRIEVGSDADIVVWDPEAERTISASTHHQNVDFNIFEGMRCHGVPLIVITNGHVVLEDDDLKVSQGTGRFVPTPPFSPYVYAKIEGRQKLRE--RIPVAREPYTGPVAD-LGAALQATDIKTVFANGKGD------QAQAFNRQRPPTSAGGRNMQDSSFALSGSQVDDALPVRSTIRTQQPPGGASRSLW 589          
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:103040013])

HSP 1 Score: 303.523 bits (776), Expect = 9.858e-95
Identity = 191/575 (33.22%), Postives = 305/575 (53.04%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNF-----NLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIG-----NEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIG-NATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGN------RNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            K+++KGG IVN D+ F +D+ IE+  IKQIG++++V    K +D    ++IPGGID +T+       +SP   D  ++ + AALAGGTT II  V  + GA L+ +    +     +  C+Y   + I    +   + +ETL +  G+N F + +         ++    +    ++L  + ++   +   ++  ++ L+  GI+GPEG   S   E E E +YR + +     C L I +VM+   A ++AK + +G  I+ E I  +L      Y+S NW ++A+ +  PP+  D      +   + CGD+ + AS H T + A +++GK +F  IP G +G+EER+S++WD+ V SG ++E EFV+ TSTNAAKIFNLYP +G IAVGS AD+VIWN  +T+T SA S +L  + NIFE + C+G P VVI  G +  +  +      +G  +  K     V  ++K    + E    G+ R   D                    D++++   + P    R P+S G       RN+  S F+LSG+Q+DD  P R+  R   PPGG+SN+
Sbjct:   16 KLIIKGGKIVNDDQSFYADIFIEDGTIKQIGENLIVPSGVKTVDAYGHIVIPGGIDVNTSLQAQHMGMSPA--DDFYHGTRAALAGGTTMIIDHVVPEPGASLLAAFDQWRDVADKRSCCDYSLHIDITRWHEGMFEELETLVKDQGVNSFLVFMSYKDRFQSSDSQMYEIFGILRDLGAIAQVHAENGDIIDEEQKRLLDMGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSRPAADVIAKARKKGMVIYGEPIAASLGTDGSHYWSQNWAKAAAFVMSPPLSPDPATPDYLNSMLSCGDLQVTASAHCTFSTAQKAVGKDNFTLIPEGTNGIEERMSIVWDKAVASGKMDENEFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWNTKETKTFSATSHNLTVEMNIFEDMECRGFPVVVISQGRIVLEDGKLDAMEGSGRFVPRKAFPDYVYKRIKARSRMAE--ARGVPRGNYDG----------------PVHDVISMTKSVPPTPTTRGPSSSGKNTPGPARNLHQSGFTLSGTQMDDHIPRRTAQRIVAPPGGRSNI 570          
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:103040013])

HSP 1 Score: 303.138 bits (775), Expect = 1.636e-93
Identity = 191/575 (33.22%), Postives = 305/575 (53.04%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN-----LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIG-----NEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIG-NATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGN------RNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            K+++KGG IVN D+ F +D+ IE+  IKQIG++++V    K +D    ++IPGGID +T+       +SP   D  ++ + AALAGGTT II  V  + GA L+ +    +     +  C+Y   + I    +   + +ETL +  G+N F + +         ++    +    ++L  + ++   +   ++  ++ L+  GI+GPEG   S   E E E +YR + +     C L I +VM+   A ++AK + +G  I+ E I  +L      Y+S NW ++A+ +  PP+  D      +   + CGD+ + AS H T + A +++GK +F  IP G +G+EER+S++WD+ V SG ++E EFV+ TSTNAAKIFNLYP +G IAVGS AD+VIWN  +T+T SA S +L  + NIFE + C+G P VVI  G +  +  +      +G  +  K     V  ++K    + E    G+ R   D                    D++++   + P    R P+S G       RN+  S F+LSG+Q+DD  P R+  R   PPGG+SN+
Sbjct:  119 KLIIKGGKIVNDDQSFYADIFIEDGTIKQIGENLIVPSGVKTVDAYGHIVIPGGIDVNTSLQAQHMGMSPA--DDFYHGTRAALAGGTTMIIDHVVPEPGASLLAAFDQWRDVADKRSCCDYSLHIDITRWHEGMFEELETLVKDQGVNSFLVFMSYKDRFQSSDSQMYEIFGILRDLGAIAQVHAENGDIIDEEQKRLLDMGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSRPAADVIAKARKKGMVIYGEPIAASLGTDGSHYWSQNWAKAAAFVMSPPLSPDPATPDYLNSMLSCGDLQVTASAHCTFSTAQKAVGKDNFTLIPEGTNGIEERMSIVWDKAVASGKMDENEFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWNTKETKTFSATSHNLTVEMNIFEDMECRGFPVVVISQGRIVLEDGKLDAMEGSGRFVPRKAFPDYVYKRIKARSRMAE--ARGVPRGNYDG----------------PVHDVISMTKSVPPTPTTRGPSSSGKNTPGPARNLHQSGFTLSGTQMDDHIPRRTAQRIVAPPGGRSNI 673          
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl5a (dihydropyrimidinase like 5 [Source:NCBI gene;Acc:103037842])

HSP 1 Score: 297.745 bits (761), Expect = 1.076e-92
Identity = 193/571 (33.80%), Postives = 312/571 (54.64%), Query Frame = 1
Query:   31 MKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPT-SGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            +++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID T KL++PGGID S +     ++    D  ++ + AALAGGTT +I  V  +    L+++ +  +S   +K  C+Y   V +     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GISGPEG   SR  E E E ++R + + +   C + +  V +     ++A  KM+G+ +  ET      ++  +Y+  +W  +A+ +T PP+R D +    ++  +    +++V S+H   T   +++GK DF  IPHGV GV++R+S++W++GV  G ++E  FV+ TS+NAAKI+NLYP +G I  G+ AD+V+W+P  TRTIS  +Q    D N++EG+ C GVP V I  G V ++   F     +G+   L+     +  KM + E  +     G+ R  +  IG   ++  + N  K   K+ V     +     QRP T  GG R++ +SSFSLSG QIDD  P RS+ R   PPGG+S+ I+
Sbjct:    8 VRILIKGGKVVNDDYTQEADVYIENGIIQQVGKELMIPGGAKVIDATGKLVLPGGIDTSVHLQETFMNATTADDFYSGTKAALAGGTTMVIGHVLPEKNESLLDAYEKCRSHADAKSCCDYALHVAVTWWGPKVRAQMETLVREKGVNSFQMFMAYKDVYMLRDSELFQALQNCKDIGAIARVHAENGELVAEGAKEALDLGISGPEGIEISRPEELEAEAVHRAITIANRAHCPIYLVNVSSMSAGDVLATAKMQGKVVHGETSTAHAVINGLQYYHQDWAHAAAYVTVPPLRLDPNTPNFLLSLLGNDSLNVVTSDHRPFTTKQKAMGKDDFTKIPHGVPGVQDRMSIIWEKGVVGGKMDENRFVAVTSSNAAKIYNLYPRKGRIIPGADADVVVWDPDATRTISVTTQWQGGDVNLYEGLRCHGVPLVTISRGRVVYENGIFTCAEGSGKFYPLRTFPDYLYKKMVQREKCQAL--KGVDR--APYIG---DVAAVQNSGK---KETVPAVGDL----AQRPCTRHGGMRDLHESSFSLSGVQIDDNLPKRSSQRILAPPGGRSSGIW 564          
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl2b (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:103036518])

HSP 1 Score: 297.36 bits (760), Expect = 2.291e-92
Identity = 193/569 (33.92%), Postives = 304/569 (53.43%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L+KG  IVN D+ F +D+ +E+ +IKQIG++++V G  K ID   ++++PGGID  T F + P+      D  +  + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + METL +  G+N F + +  +      ++    V    ++L  + ++   +   +   +  ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  + ++A+ + +G  ++ E I  ++      Y+S NW ++A+ +T PP+  D      +   + CGD+ +V S H T   A R++GK DF  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAKIFNLYP +G IAVGS AD+V+W+P  T+ ISA S +   + NIFEG+  +G P VVI  G +  +         +G  +  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K    P     RN+  S FSLSG+Q+DD  P R+T R   PPGG++N+
Sbjct:   17 RLLIKGAKIVNDDQSFSADIYMEDGLIKQIGENLIVPGGVKTIDAHGQMVMPGGIDVHTRFQM-PDRGMTAADDFYQGTRAALAGGTTMIIDHVVAEPGVGLIAAFNQWREWADSKSCCDYSLHVDITEWHKGIQEEMETLVKDHGVNSFLVYLAYKDVFQLTDSQIYEVFSGIRDLGAIAQVHAENGDIIAEEQRRILELGITGPEGHVLSRPEEVEAEAVNRSVTVANQTNCPLYITKVMSKSASDVIAQARKKGTVVYGEPITASVGTDGSHYWSKNWGKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQVVGSGHCTFNTAQRAVGKDDFTLIPEGTNGAEERMSIIWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNSAVEYNIFEGMEVRGAPLVVISQGKIVLEEGTLHTTEGSGRYVPRKPFPDYVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKAVTPASSAKTSPAKQASQPV----RNLHQSGFSLSGAQVDDNIPRRNTQRIVAPPGGRANI 569          
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl2b (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:103036518])

HSP 1 Score: 297.745 bits (761), Expect = 6.746e-92
Identity = 194/575 (33.74%), Postives = 307/575 (53.39%), Query Frame = 1
Query:   16 LNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            +N  + ++L+KG  IVN D+ F +D+ +E+ +IKQIG++++V G  K ID   ++++PGGID  T F + P+      D  +  + AALAGGTT II  V  + G  L+ +    +    SK  C+Y   V I        + METL +  G+N F + +  +      ++    V    ++L  + ++   +   +   +  ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  + ++A+ + +G  ++ E I  ++      Y+S NW ++A+ +T PP+  D      +   + CGD+ +V S H T   A R++GK DF  IP G +G EER+S++WD+ V +G ++E +FV+ TSTNAAKIFNLYP +G IAVGS AD+V+W+P  T+ ISA S +   + NIFEG+  +G P VVI  G +  +         +G  +  K     V  ++K    L E    G+ R + D  G   E+        V  K +    S K +P K    P     RN+  S FSLSG+Q+DD  P R+T R   PPGG++N+
Sbjct:   65 INDTSDRLLIKGAKIVNDDQSFSADIYMEDGLIKQIGENLIVPGGVKTIDAHGQMVMPGGIDVHTRFQM-PDRGMTAADDFYQGTRAALAGGTTMIIDHVVAEPGVGLIAAFNQWREWADSKSCCDYSLHVDITEWHKGIQEEMETLVKDHGVNSFLVYLAYKDVFQLTDSQIYEVFSGIRDLGAIAQVHAENGDIIAEEQRRILELGITGPEGHVLSRPEEVEAEAVNRSVTVANQTNCPLYITKVMSKSASDVIAQARKKGTVVYGEPITASVGTDGSHYWSKNWGKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQVVGSGHCTFNTAQRAVGKDDFTLIPEGTNGAEERMSIIWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNSAVEYNIFEGMEVRGAPLVVISQGKIVLEEGTLHTTEGSGRYVPRKPFPDYVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKAVTPASSAKTSPAKQASQPV----RNLHQSGFSLSGAQVDDNIPRRNTQRIVAPPGGRANI 623          
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: dpysl3 (dihydropyrimidinase like 3 [Source:NCBI gene;Acc:553166])

HSP 1 Score: 243.817 bits (621), Expect = 6.680e-74
Identity = 151/478 (31.59%), Postives = 245/478 (51.26%), Query Frame = 1
Query:  310 QSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGN-ATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDN----IGVASEIRTINNPHKVIQKDIVTVDSKINPLK--MQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            + G  LV +L A +    +KV C+Y   V +    +   + +E L +  GIN F + +  +      +     V    +++  +  +   +   +   ++ ++  GI+GPEG   SR  E E E + R + + +   C L I +VM++  A ++++ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D      +   + CGD+ +  S H T T A +++GK +F  IP G +G+EER+S++WD+ V +G ++E +FV+ TSTNAAKIF+LYP +G IAVGS AD+VIW P    TISA +     + NIFEG+  +G P VVI  G +  +  +       G  +  K   + V  ++K    L E    G+ R + D     +  +S   T   P         T  ++ +P K   Q  P     RN+  S FSLSG+Q+DDE P R+  R   PPGG+SN+
Sbjct:    8 EPGQGLVAALDAWREWADAKVCCDYSLHVAVPQWHEGVAEELEILVKDRGINSFLVYMAYKDQYQMSDTEMYEVFTFLRDIGAIAMVHAENGDIIAEEQKRILEMGIAGPEGHVLSRAEEVEAEAVNRAISIANHTNCPLYITKVMSKSAADVISQARKKGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNSLLSCGDLQVTGSAHCTFTTAQKALGKDNFTLIPEGTNGIEERMSIVWDKAVATGKMDENQFVAVTSTNAAKIFSLYPRKGRIAVGSDADLVIWEPDTITTISAKTHTAAVEYNIFEGMEVRGAPLVVISQGRIVLEEGKLSATQGAGRFVPRKAFPEQVYKRIKARNKLAEM--RGVPRGLYDGPVFELSSSSVRSTTATP---------TPSARTSPAKSAAQSAPL----RNLHQSGFSLSGAQVDDELPRRTGHRIVAPPGGRSNI 470          
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006054.1 (pep scaffold:Pmarinus_7.0:GL477305:540:7425:1 gene:ENSPMAG00000005460.1 transcript:ENSPMAT00000006054.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 171.4 bits (433), Expect = 2.944e-49
Identity = 98/263 (37.26%), Postives = 148/263 (56.27%), Query Frame = 1
Query:  925 CGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIG-NATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGN---RNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
             GD+ +  S H T + A +++GK DF  IP G +G+EER+S++WD+GV +G ++E +FV+ TSTNAAK+FNLYP +G IAVGS AD++IW+P   +TISA + H   + NIFEG+  +GVP  VI  G +  +          G  +  K   + V  ++K    L E    G+ R + D  G   E+ T+++     +       +K +P +      +      RN+  S F LSG+Q+DD  P R+  R   PPGG+SN+
Sbjct:    1 SGDLHVTGSAHCTFSTAQKALGKDDFTLIPEGTNGIEERMSIVWDKGVATGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLIIWDPDVVKTISAKTHHQAVEYNIFEGMEVRGVPLAVISQGKIVMEDGTLHAMQGVGRFVPRKAFPEQVYKRIKARSQLTEL--QGVPRGLYD--GPVQEV-TVSS-----RTATPAASAKTSPTRQTAAAAAAQASNLRNLHQSGFCLSGAQVDDNMPRRTGHRIVAPPGGRSNI 253          
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: dpysl2b (dihydropyrimidinase like 2b [Source:ZFIN;Acc:ZDB-GENE-031105-1])

HSP 1 Score: 99.7525 bits (247), Expect = 8.917e-24
Identity = 76/261 (29.12%), Postives = 134/261 (51.34%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVA--KMKMEGRPI 786
            ++L+KGG I+N D+ F +D+ +E+  IKQIG +++V G  K I+   ++++PGGID  T+     L  +  D  +  + AALAGGTT II  V  + G  L+ + +  +    +K  C+Y   VQ+     E    METL +  G+N F + +  +      +A         ++L  +  +   + + +   ++ ++   I+GPEG   SR  E E E + R + + +   C L I +VM+   A ++A  + K+ G+ I
Sbjct:    2 RLLIKGGRIINDDQSFTADIYVEDGFIKQIGDNLIVPGGVKSIEANGRMVMPGGIDVHTHLQMPYLGTSTMDDFYQGTRAALAGGTTMIIDHVIPEPGCSLLGAYEQWREWADAKACCDYSLHVQLTYWNSELCSEMETLIKDKGVNSFLVYMAYKDKYQLTDAEIYEAFTAIRDLGAIALVHAENGSIIAEEQKRILGLQITGPEGHVLSRPEEVEAEAVNRAITIGNQTNCPLYITKVMSRSAADVIALSRKKVRGQYI 262          
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO46551 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPQ7])

HSP 1 Score: 298.901 bits (764), Expect = 1.785e-93
Identity = 204/583 (34.99%), Postives = 310/583 (53.17%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE----IN-ANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGE-------------RIDLK-INCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            ++L+KGG IVN D+ F++DV IEN +IK+I +S++  G TKVID + KLI+PGGID  T+  +        D     + AALAGGTT II  V    G  L+ +    +     KV C+YGF V +    +E  + ME L ++ GIN F+  +  +    IN A  ++  KKCKE+  + ++   +   ++   +++I  GI+GPEG    R  E E E   R + + +   C L +  VM++  AK+++  +  G+ +  E I   L      Y+   W   A  +  PP+R D      ++  +   D+    +++ T ++  +++GK DFR IP+GV+G+E+R+S++W++GV +G ++ C FV+ TST AAKIFN+YP +G IAVGS ADIV+W+P  TR ISA + H   D NIFEG+ C GVP V I  G V ++  EF +   +G              RI  +  NCQ  K   + Y      GK+ +T E      V        +P +   K+   V  K NP           +R++  S F LSG Q DDE+P R + R   PPGG S+++F
Sbjct:   10 RILIKGGTIVNDDQMFEADVYIENGLIKEISKSVICPGGTKVIDASRKLILPGGIDTHTHLQMPFMGTTAIDDFFIGTKAALAGGTTMIIDFVIPAKGESLLEAYDKWRGWADEKVCCDYGFHVAVTWWSEEVAEEMEILVKEKGINSFKTFMAYKDVMMINDAEMINCYKKCKEIGAIAQVHAENGDLIDESAKKMIAMGITGPEGHEMCRPEEVEAEATQRAITIANQVSCPLYVVHVMSKSSAKVISDARRLGKVVIGEPIAAGLGCDGTNYWHKCWRHGAGHVMGPPLRPDTSTPEHLMNLLANDDLQCTGTDNCTFSSEQKALGKNDFRKIPNGVNGIEDRMSVIWEKGVHAGKMDPCRFVAVTSTTAAKIFNVYPQKGRIAVGSDADIVVWDPEATRVISAKTHHQAVDFNIFEGMECHGVPVVTISQGKVVYEGGEFHVVRGSGRFIPTPPFSHYMYSRIHTRDKNCQPKKVDREPYT-----GKV-LTIEPDPKAAV------FTSPAQRRMKEREEV--KKNP-----------HRDLHRSGFELSGRQFDDERPYRPSSRVAKPPGGASSIVF 567          
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO49158 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH45])

HSP 1 Score: 60.4622 bits (145), Expect = 9.912e-10
Identity = 46/180 (25.56%), Postives = 80/180 (44.44%), Query Frame = 1
Query:  805 PALALSSHKYFSNNWDESASLITD----PPIRNDQDAAII-RSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLN 1329
            P    ++H Y S   +E     T     PPIR+  +  ++  ++   DID+V S+H+  T   + + + DF     G+S ++  LS+ W  G +   +   + V       +K+ +L   +G I+VG  AD VIW+P +   + +     +N    + G    G     I+ G V F  N
Sbjct:  201 PLTVETTHHYLSLTAEEVPDGATQYKCCPPIRDRSNQEVLWNAVKFRDIDLVVSDHSPCTPDLKLLDQGDFIGAWGGISSLQYGLSLFWS-GARCRGLGLHDVVRVLCEQPSKLCSLQHRKGMISVGKDADFVIWDPNEEFMVKSSDIRHRNKVTPYAGKKLFGRVHQTILRGQVVFSGN 379          
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl4 (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:101156240])

HSP 1 Score: 309.301 bits (791), Expect = 4.772e-97
Identity = 194/575 (33.74%), Postives = 312/575 (54.26%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN-----LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKF---QLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQR----PPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++++KGG IVN D+ F +DV +E+  IKQIG++++V    K +D   +L+IPGGID +TN +     +SP   D  +  + AAL+GGTTTI+  V  + G+ L+     ++   +    C++   + I    D   + +ETL +  G+N F   +  +    ++++                +VH  +   ++  + ++++ GI+GPEG   S   E E E +YR + +     C L I +VM++  A ++AK + +G  ++ E I  +LA     Y+S +W  +A+L+  PP+  D      +   + CGD+ + +S   + + A +++GK DF  IP G +G+EER++++WDR V SG ++E EFV+ TSTNAAK+FN+YP +G IAVGS ADIV+WNP +TRT+SA + +L  + NI EG+  +GVP VVI  G V     QLN  +   +G  +  K     V      Y+ ++   KM  TR +           + + P      D+ ++   + P    R    P T  G RN+  S F+L+GSQIDD  P RS  R   PPGG+SN+
Sbjct:   16 RLIIKGGKIVNDDQSFYADVFVEDGTIKQIGENLIVPPGVKTVDAYGQLVIPGGIDANTNLHTPQKGMSP--VDGFYQGTRAALSGGTTTIMDHVLVEPGSSLLAVFDQMKETAEQTACCDFSLHLDIARWHDGLSEELETLVKDKGVNSFLFFMAYKDKYQSSDSQLYEAFGVLRDLGAIAQVHAENGDIIDEEQRKVLSLGITGPEGHALSHPEEVETEAVYRAITVAKQANCPLYITKVMSKSAADVIAKARKKGMVVYGEPITASLATDGSHYWSKDWATAAALVMSPPLNPDPSTPQYLTSLLACGDLQVTSSAQASFSTAQKAVGKDDFTLIPEGTNGIEERMAVVWDRAVFSGKMDENEFVAVTSTNAAKLFNMYPRKGRIAVGSDADIVVWNPKETRTVSAKTHNLTLEVNILEGLEFRGVPAVVISGGRVVLENGQLN--VTEGSGRFVPRKAFPDAV------YKRIKARSKMAETRGVPRG--------SYDGP----VHDVTSMMKSVPPTPTSRGPPCPKTQAGLRNLHQSGFTLAGSQIDDHIPRRSAQRIVAPPGGRSNI 568          
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl2b (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:101155946])

HSP 1 Score: 296.59 bits (758), Expect = 3.784e-92
Identity = 193/569 (33.92%), Postives = 306/569 (53.78%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNH----RDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQL-NEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDS-KINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            ++L++G  IVN D+ F +DV +E+ +IKQIG++++V G  K ID   ++++PGGID  T F + P+      D  +  + AALAGGTT I+  V  + G  L+++ +  +    SK  C+Y   + I        + METL +  G+N F + +  +      +A    V    ++L  + ++   +   +   +  ++  GI+GPEG   S   E E E + R + + +   C L + +VM++  A ++A+ + +G  ++ E I  +L      Y+S NW ++A+ +T PP+  D      +   + CGD+ +  S H     A R++GK DF  IP GV+G EER+S++WD+ V +G ++E +FV+ TSTNAAKIFNLYP +G IAVGS AD+V+W+P  T+ ISA S +   + NIFEG   +G P VVI  G +  +  N  +   +G  +  K     V  ++K    L E    G+ R + D  G   E+        V  K +  V S K +P K    P     RN+  S FSLSG+Q+DD  P R+T R   PPGG++N+
Sbjct:   17 RLLIRGAKIVNDDQSFCADVYMEDGVIKQIGENLIVPGGVKTIDAHGRMLMPGGIDVHTRFQM-PDRGMTAADDFYQGTKAALAGGTTMILDHVLPEPGVSLLSAFEQWREWADSKACCDYSLHIDITEWHKGIQEEMETLVKDHGVNSFLVYLAYKDIFQLTDAQVYEVFSVIRDLGAIAQVHAENGDIVAEEQRRILEQGITGPEGHVLSHPEEVEAEAVNRSVTVANQTNCPLYVTKVMSKSAADVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQVTGSAHCPFNTAQRAVGKDDFTLIPEGVNGTEERMSIIWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNSTVEYNIFEGTEVRGGPLVVISQGKIILEEGNLHVTEGSGRFVARKPFPDYVYKRIKARSRLAEL--RGVPRGLYD--GPVCEV-------SVTPKTMTPVSSAKTSPAKQPSQPV----RNLHQSGFSLSGAQVDDNIPRRNTQRIVAPPGGRANI 569          
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl5b (dihydropyrimidinase like 5 [Source:NCBI gene;Acc:101174151])

HSP 1 Score: 296.204 bits (757), Expect = 4.681e-92
Identity = 189/574 (32.93%), Postives = 312/574 (54.36%), Query Frame = 1
Query:   19 NFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE---INANTVSVXXXXXXXXXXXXXRVH--DSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDA-AIIRSIHCGD-IDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFI-GNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            N  +M++L+KGG +VN D   ++DV IEN II+Q+G+ +++ G  KVID + KL++PGGID S +     ++ + +D  +N + AAL GGTT ++ LV  +    L+++ +  ++   +K  C+Y   V +     +    METL R+ G+N FQM +  +   +  ++                RVH  +   +    +E +  GISGPEG   SR  E E E  +R + + +   C + +  V +     +VA  KM+ + +++ET      LS  +Y+  +W  SA+ +  PP+R D +    +  +   D + +VASEH       R++GK DF  IPHGV+GV++R+S++W+RGV +G ++E  FV+ TS+NAAKI+N+YP +G I  G+ AD+V+W+P  T+TIS  +Q    D N++EG+ C GVP V I  G +  + + F+    +G+   L      +  KM + E  + +  +       D   VA+ I+         +  +  +D + +     R     G R++ +SSFSLSGSQ+DD  P RS+ R   PPGG+S+ I+
Sbjct:    4 NMGSMRILIKGGKVVNDDFTQEADVYIENGIIQQVGKELMIPGGAKVIDASGKLVLPGGIDTSVHLQQTFMNASIQDDFYNGTKAALMGGTTMVMALVLPEQHCSLLDAYEKCRALADAKTCCDYSLHVGVTWWGPKVHNEMETLVREHGVNSFQMYMAYKDMMMLRDSELYQTLQTCKDIGAIARVHAENGELVAEGAKEALDLGISGPEGIEISRPEELESEATHRAITIANRARCPIYLVNVSSVSAGDMVAAAKMQDKVVYAETTVAHAVLSGMQYYHQDWAHSAAHVIVPPLRLDPNTPGYLMGLLANDTLSVVASEHRPFNTKQRALGKEDFTKIPHGVAGVQDRMSVIWERGVVTGKMDENRFVAVTSSNAAKIYNMYPRKGRIIPGADADVVVWDPDATKTISVTTQVQGGDFNLYEGMRCHGVPLVTISRGRLVCENSMFMCAEGSGKFYPLHTFPDYLYKKMVQREKTQSYKGVARDPYSGDVAKVANTIKR--------ELGLGPIDGESSNKASAR--IHQGVRDLHESSFSLSGSQVDDHIPKRSSARILAPPGGRSSGIW 567          
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: crmp1 (dihydropyrimidinase-related protein 1 [Source:NCBI gene;Acc:101159888])

HSP 1 Score: 286.189 bits (731), Expect = 1.882e-88
Identity = 196/555 (35.32%), Postives = 295/555 (53.15%), Query Frame = 1
Query:   73 RKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNF---NLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVK-SMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEF-IGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNL 1701
            R F  DV IE+ +IKQ+G+++VV G  KVI+   +++IPGGID +T      L     D     + AALAGGTT II  V  + G  L+ + +  Q     +  C+Y   V I P  +E VK  +E L +  GIN FQ+ +  +      ++         K+L  ++ +   +   +   + +++  GI+GPEG   SR  E E E ++R + L +   C + I +VM++  A  +A+ + +G  +F E I   LA     Y+S NW ++A+ +T PP+  D      +   +  GD+ +V S H   + + ++IGK DF  IP G +GVEER+  +WD+ V  G ++E +FV+ TSTNAAKIFNLYP +G IAV S ADIVIW+P   +TI+A  Q    + NIFEG+ C+G P +V+  G V ++  +  I   TG  I  K        ++K    +    K G+TR + D       +  +    K I     +  +K +P   Q PPT    RN+  S+FSLSG+QIDD  P RS  R   PPGG+SN+
Sbjct:    1 RSFFGDVYIEDGLIKQVGENLVVPGGVKVIEANGRMVIPGGIDVNTCLMKTYLGTQPVDDFLQGTKAALAGGTTMIIDHVTPEPGESLLEAFERWQEAADKRACCDYSLHVDI-PLWNETVKDELEVLVQDKGINSFQVYMAYKDVYQMTDSQLYEAFSFLKQLGAVVLVHAENGDLIFEEQRKILGMGITGPEGHPLSRPEEVEAEAVFRAITLGNCVNCPVYITKVMSKSAADTIAQARRKGSVVFGEPITAGLATDGSHYWSKNWAKAAAYVTSPPLSPDPTTPEHLHTLLASGDLQVVGSSHCAYSTSQKAIGKDDFTLIPEGTNGVEERMGFVWDKAVAMGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVDSDADIVIWDPDIVKTITAKQQQSAAEYNIFEGLECRGGPALVLSQGRVVYEGGKLQIQQGTGRFIPRKPFPDYAFQRIKFRNQVSS--KQGVTRGVYDG-----PVHDVTPTPKYITP---SPSAKTSPTSHQ-PPTV---RNLHLSNFSLSGAQIDDNIPRRSGHRIVAPPGGRSNI 540          
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl3 (dihydropyrimidinase-related protein 3 [Source:NCBI gene;Acc:101165934])

HSP 1 Score: 281.182 bits (718), Expect = 1.983e-85
Identity = 185/572 (32.34%), Postives = 300/572 (52.45%), Query Frame = 1
Query:   25 KTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNL---SPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNE-----INANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKD-KMKRYECLREFGKM-GITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIR-STIRTNHPPGGKSNL 1701
            K+ ++L+KGG IVN D+ F +D+ +E+ +IKQIG +++V G  K I+   K++IPGGID  T+F +        D     S AALAGGTT I+  V  + G  L+ +    +     K  C+Y   V I    D   + +++L +  G+N FQ+ +  +      N+    +     E   ++++   +   +   +  ++  GI+GPEG   SR  E E E ++R + +     C L + +VM++  A ++++ + +G  +F E I  +L      Y+S NW ++A+ +T PP+  D      +   +  GD+ +  S H T + A ++IGK DF  IP GV+GVEER++++WD+ V +G ++E  FV+ TSTNAAKI NLYP +G IAVGS AD++IW+    RTI+A + +   + NIFEG+  +G P VVI  G +  +  +    +   R    I C    D   KR +  ++   +  + R + D  G  SE         + +    +  ++ +P K    P     RN+  S FSL+G    DE PIR +  R   PPGG+SN+
Sbjct:   97 KSDRLLIKGGRIVNDDQSFHADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHFQMPYRGTTTVDDFAQGSKAALAGGTTMIVDHVIPEPGTSLMEAYDQWRQWADEKACCDYSLHVDITHWNDSVKQEVDSLIKDKGVNSFQVYMAYKDYYQLSNSQLYEIFTFLAEKGGIVQVHAENGEIIAEEQARMLQMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAADIISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNTLLASGDLSVTGSAHCTFSVAQKAIGKDDFTQIPEGVNGVEERMALIWDKAVTTGKMDENMFVAITSTNAAKILNLYPRKGRIAVGSDADLIIWDTDSVRTITAKTHNSAAEYNIFEGMELRGAPLVVICQGKIVLEDGKLQVTSGAGRF---IPCSPFPDFAYKRVKARKQLAVLRAVPRGMYD--GPVSEF-------SMSRGGTPSASARTSPTKQ---PV----RNLHQSGFSLTGPPTPDEVPIRPAGRRIVVPPGGRSNI 649          
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000028784.1 (SMESG000028784.1)

HSP 1 Score: 1082.78 bits (2799), Expect = 0.000e+0
Identity = 555/559 (99.28%), Postives = 557/559 (99.64%), Query Frame = 1
Query:   31 MKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            MKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPN+DECVKSME LARQFGINCFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPP+RNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINN HKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF
Sbjct:    1 MKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNDDECVKSMEKLARQFGINCFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPVRNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNSHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 559          
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000028784.1 (SMESG000028784.1)

HSP 1 Score: 1078.54 bits (2788), Expect = 0.000e+0
Identity = 553/557 (99.28%), Postives = 555/557 (99.64%), Query Frame = 1
Query:   37 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPN+DECVKSME LARQFGINCFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPP+RNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINN HKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF
Sbjct:    1 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNDDECVKSMEKLARQFGINCFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPVRNDQDAAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNSHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 557          
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000002633.1 (SMESG000002633.1)

HSP 1 Score: 340.502 bits (872), Expect = 6.304e-109
Identity = 215/573 (37.52%), Postives = 327/573 (57.07%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLARQFGINCFQMTIGNEI-----NANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQN-DTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMK-RYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINP--LKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 1707
            ++ +KG  IVN DR F +DV IE+ IIKQ+G ++V+ G  + ++   KL+IPGGID  T+     +     D  ++ + AALAGGTT II  V  Q G  L++S    +    SKV C+YG  V +    +     ME LA + GIN F++ +  +      +     V KKCK +  L ++   +   +E    ELI+ GI+GPEG   SR  E E E   R + L     C L +  VM++  A +++  + +G+ +F E I   L      Y  + W  +A  +  PP+RND++ +  +++ +  GD++   ++H     + +++GK DFR+IP+GV+GVE+R+S++W++GV +GI++ C+FV+ TSTNAAKIFN+YP +G I +GS AD+V+WNP   RTISA S H QN D NIFEG+ C GV E+VI  G V  +  N  +   TG+ +     C  V +K+K R +C +      + R+  D   V    + + N +     D  +  + I+   +  +RP TSGG R+MQDSSF+LSG+QIDD  P RS IRT  PPGG +  ++
Sbjct:   23 RLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISA-STHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANK-VERQPYDGP-VEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 592          
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000060188.1 (SMESG000060188.1)

HSP 1 Score: 164.466 bits (415), Expect = 1.840e-43
Identity = 155/586 (26.45%), Postives = 271/586 (46.25%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN------LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSK-VLCNYGF---------CVQIDPNEDECVKSMETLARQFGIN--CFQMTIGNEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVM-NEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA-----IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKP--------IRSTIRTNHPPGGKS 1695
            K+L+K G ++N D  + +DVLIEN  I  I ++I  S   + ID T   ++PGG+D  TNF       +SP +       ++          + ++K++S  E       ++ D+ SK ++CN             ++ + NE    KS+  L R   ++  C  + I +E        L  C++   L  +   +   +  +E+EL+  G++GPEG + SR  + E E ++R+L +  +  C +   +V     + K++   +     I   T   AL  ++ KY   NW  +AS +T P ++ +++       ++ ++    I+ VAS H       ++ G+ DFR I  G +GV+ R+ +LWD+ VKSG +    FV+  ST  AK+ N+YP +G I++GS ADI++W   K  ++S  S     D N+FE + C   P+ VIVNG V     +  GN T      K + Q+V   ++       F K  I  ++S+ +    E +    P+             I+P    +        +M ++     G   +D+K         IR++++T  PPGG +
Sbjct:    7 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSL-AECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYE----MEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDE---ELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKNTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW---KGDSVSH-SNFEAGDINVFEDVICHSGPKYVIVNGIVVL---DHEGNFTAS----KGSGQIVSPSLETMNSY--FQKQLINYKLSNEV----EKKIAREPYD---------GPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 558          
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000060188.1 (SMESG000060188.1)

HSP 1 Score: 164.466 bits (415), Expect = 2.376e-43
Identity = 155/586 (26.45%), Postives = 271/586 (46.25%), Query Frame = 1
Query:   34 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN------LSPNHRDILHNESMXXXXXXXXXXXXXVKEQSGAELVNSLKALQSDLKSK-VLCNYGF---------CVQIDPNEDECVKSMETLARQFGIN--CFQMTIGNEINANTVSVXXXXXXXXXXXXXRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVM-NEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQDAA-----IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNATGERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINNPHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKP--------IRSTIRTNHPPGGKS 1695
            K+L+K G ++N D  + +DVLIEN  I  I ++I  S   + ID T   ++PGG+D  TNF       +SP +       ++          + ++K++S  E       ++ D+ SK ++CN             ++ + NE    KS+  L R   ++  C  + I +E        L  C++   L  +   +   +  +E+EL+  G++GPEG + SR  + E E ++R+L +  +  C +   +V     + K++   +     I   T   AL  ++ KY   NW  +AS +T P ++ +++       ++ ++    I+ VAS H       ++ G+ DFR I  G +GV+ R+ +LWD+ VKSG +    FV+  ST  AK+ N+YP +G I++GS ADI++W   K  ++S  S     D N+FE + C   P+ VIVNG V     +  GN T      K + Q+V   ++       F K  I  ++S+ +    E +    P+             I+P    +        +M ++     G   +D+K         IR++++T  PPGG +
Sbjct:   10 KLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIEDSL-AECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYE----MEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPLVRLSTVDKGCHCVKIDDE---ELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVALVHNAEKYRDPNWKVAASFVTMPALKMNKNTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVW---KGDSVSH-SNFEAGDINVFEDVICHSGPKYVIVNGIVVL---DHEGNFTAS----KGSGQIVSPSLETMNSY--FQKQLINYKLSNEV----EKKIAREPYD---------GPVIDPSADNKEEKHVLYSHMVNNDVYKRGGPAEDKKEALPPGQRVIRTSVKTAQPPGGSA 561          
The following BLAST results are available for this feature:
BLAST of Dihydropyrimidinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DPYSL57.487e-9734.54dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc... [more]
DPYSL57.487e-9734.54dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc... [more]
DPYSL57.487e-9734.54dihydropyrimidinase like 5 [Source:HGNC Symbol;Acc... [more]
DPYSL22.038e-9634.45dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc... [more]
DPYSL21.017e-9534.26dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dhp-25.515e-8136.83Dihydropyrimidinase 2 [Source:UniProtKB/Swiss-Pro... [more]
dhp-11.018e-7834.16Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Pro... [more]
dhp-11.018e-7834.16Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Pro... [more]
dhp-11.018e-7834.16Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Pro... [more]
unc-333.262e-5029.33pep chromosome:WBcel235:IV:3518147:3525572:1 gene:... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CRMP7.219e-7631.03gene:FBgn0023023 transcript:FBtr0114453[more]
CRMP2.655e-7530.80gene:FBgn0023023 transcript:FBtr0089686[more]
CRMP9.309e-2529.67gene:FBgn0023023 transcript:FBtr0089685[more]
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BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpysl5a1.598e-9633.92dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-G... [more]
dpysl5a1.598e-9633.92dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-G... [more]
dpysl41.094e-9534.09dihydropyrimidinase like 4 [Source:ZFIN;Acc:ZDB-GE... [more]
dpysl5a2.111e-9533.22dihydropyrimidinase like 5a [Source:ZFIN;Acc:ZDB-G... [more]
crmp12.310e-9535.65collapsin response mediator protein 1 [Source:ZFIN... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpysl41.461e-9534.33dihydropyrimidinase like 4 [Source:NCBI gene;Acc:5... [more]
dpysl41.478e-9534.20dihydropyrimidinase like 4 [Source:NCBI gene;Acc:5... [more]
dpysl41.639e-9534.33dihydropyrimidinase like 4 [Source:NCBI gene;Acc:5... [more]
dpysl42.533e-9534.03dihydropyrimidinase like 4 [Source:NCBI gene;Acc:5... [more]
bco22.019e-9434.84beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-G... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dpysl23.793e-9634.09dihydropyrimidinase-like 2 [Source:MGI Symbol;Acc:... [more]
Dpysl45.326e-9634.74dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:... [more]
Dpysl45.326e-9634.74dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:... [more]
Dpysl41.033e-9534.74dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:... [more]
Dpysl41.033e-9534.74dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:... [more]
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BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q90635|DPYL2_CHICK1.574e-9734.68Dihydropyrimidinase-related protein 2 OS=Gallus ga... [more]
sp|Q9BPU6|DPYL5_HUMAN3.595e-9634.54Dihydropyrimidinase-related protein 5 OS=Homo sapi... [more]
sp|O02675|DPYL2_BOVIN3.686e-9634.45Dihydropyrimidinase-related protein 2 OS=Bos tauru... [more]
sp|Q62951|DPYL4_RAT4.789e-9634.92Dihydropyrimidinase-related protein 4 (Fragment) O... [more]
sp|Q9JHU0|DPYL5_RAT7.401e-9634.72Dihydropyrimidinase-related protein 5 OS=Rattus no... [more]
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BLAST of Dihydropyrimidinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K1PGY51.497e-10637.30Dihydropyrimidinase OS=Crassostrea gigas OX=29159 ... [more]
A0A1W7RAR01.795e-10535.28Dihydropyrimidinase OS=Hadrurus spadix OX=141984 P... [more]
A0A267FG465.373e-10335.20Amidohydro-rel domain-containing protein OS=Macros... [more]
A0A183TGQ29.600e-10335.89Dihydropyrimidinase OS=Schistocephalus solidus OX=... [more]
A0A3P7D5Z09.911e-10335.89Amidohydro-rel domain-containing protein OS=Schist... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpysl49.858e-9533.22dihydropyrimidinase like 4 [Source:NCBI gene;Acc:1... [more]
dpysl41.636e-9333.22dihydropyrimidinase like 4 [Source:NCBI gene;Acc:1... [more]
dpysl5a1.076e-9233.80dihydropyrimidinase like 5 [Source:NCBI gene;Acc:1... [more]
dpysl2b2.291e-9233.92dihydropyrimidinase-related protein 2 [Source:NCBI... [more]
dpysl2b6.746e-9233.74dihydropyrimidinase-related protein 2 [Source:NCBI... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
dpysl36.680e-7431.59dihydropyrimidinase like 3 [Source:NCBI gene;Acc:5... [more]
ENSPMAT00000006054.12.944e-4937.26pep scaffold:Pmarinus_7.0:GL477305:540:7425:1 gene... [more]
dpysl2b8.917e-2429.12dihydropyrimidinase like 2b [Source:ZFIN;Acc:ZDB-G... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO465511.785e-9334.99Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO491589.912e-1025.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpysl44.772e-9733.74dihydropyrimidinase-related protein 2 [Source:NCBI... [more]
dpysl2b3.784e-9233.92dihydropyrimidinase-related protein 2 [Source:NCBI... [more]
dpysl5b4.681e-9232.93dihydropyrimidinase like 5 [Source:NCBI gene;Acc:1... [more]
crmp11.882e-8835.32dihydropyrimidinase-related protein 1 [Source:NCBI... [more]
dpysl31.983e-8532.34dihydropyrimidinase-related protein 3 [Source:NCBI... [more]
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BLAST of Dihydropyrimidinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000028784.10.000e+099.28SMESG000028784.1[more]
SMESG000028784.10.000e+099.28SMESG000028784.1[more]
SMESG000002633.16.304e-10937.52SMESG000002633.1[more]
SMESG000060188.11.840e-4326.45SMESG000060188.1[more]
SMESG000060188.12.376e-4326.45SMESG000060188.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022905 ID=SMED30022905|Name=Dihydropyrimidinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1893bp
ATGGGTGAATACATTTTAAATTTCAAAACTATGAAAATGCTGTTAAAAGG
AGGATATATTGTAAATAGTGACAGAAAATTTCAGTCTGACGTACTAATTG
AAAATAATATAATCAAACAAATTGGCCAAAGCATTGTTGTAAGTGGTGAC
ACTAAAGTGATTGATGTAACAAACAAACTTATCATTCCCGGTGGCATAGA
TCCAAGCACCAATTTTAATTTATCTCCGAACCACAGAGATATTCTTCACA
ATGAATCAATGGCTGCCTTAGCCGGCGGAACAACGACTATAATTACTCTT
GTTAAAGAACAAAGCGGTGCTGAGTTAGTAAATTCATTGAAAGCACTTCA
GTCAGATCTAAAATCGAAAGTATTGTGTAATTATGGATTTTGTGTGCAAA
TTGATCCAAATGAGGACGAATGCGTAAAATCCATGGAAACATTGGCACGA
CAATTTGGAATAAATTGCTTCCAAATGACAATAGGAAATGAAATAAACGC
TAACACTGTTTCAGTTCTGAAAAAATGTAAAGAATTACAATGCTTACTCA
AATTGCGAGTCCATGATTCTACATACCTTGAAGCAGTGGAAGAAGAATTA
ATAACTGCAGGCATTTCTGGACCAGAAGGCTTCTTCCAATCTCGATGTAT
TGAAAATGAAATGGAGCAATTATATCGAATTTTAAAGTTAAACCATGTTT
TTCCTTGTTGTCTGATCATACCACAAGTTATGAACGAAGACATTGCAAAA
CTTGTCGCAAAAATGAAAATGGAAGGACGACCTATCTTTTCCGAAACCAT
TCCACCCGCTCTTGCTTTATCAAGTCACAAGTACTTCTCAAATAATTGGG
ATGAATCAGCATCATTAATTACAGATCCACCTATACGAAATGATCAGGAT
GCAGCAATAATACGAAGCATTCATTGTGGAGATATCGACATGGTGGCATC
GGAACATACAACAATAACGAATGCAGATCGATCGATTGGGAAGAGAGATT
TTAGAAACATACCTCATGGAGTTTCTGGCGTTGAGGAGAGATTGTCAATG
CTGTGGGATAGAGGAGTGAAATCTGGAATTATAAATGAATGCGAATTTGT
TTCGGCAACAAGTACAAACGCTGCAAAAATCTTCAACCTTTATCCAGACC
GAGGACACATTGCAGTTGGGAGCGTAGCCGATATTGTTATTTGGAATCCA
GTAAAAACAAGAACCATTTCTGCTTTATCTCAACACTTGCAAAACGATAC
AAATATTTTTGAAGGGATTTCTTGTCAAGGAGTTCCGGAAGTTGTAATTG
TGAATGGATCTGTCAAATTTCAGTTGAATGAGTTCATTGGAAACGCGACC
GGAGAAAGAATAGATTTAAAAATTAATTGTCAAGTTGTAAAAGATAAAAT
GAAGAGATATGAATGCCTACGAGAGTTTGGGAAAATGGGAATAACTCGGG
AAATCAGTGATAATATCGGAGTTGCCAGTGAAATTAGAACCATAAATAAT
CCACATAAAGTGATTCAGAAAGATATTGTAACTGTCGATAGTAAAATTAA
TCCGCTTAAAATGCAAAGACCTCCAACAAGTGGCGGAAATAGAAATATGC
AAGACTCAAGTTTTTCATTAAGTGGATCTCAAATCGACGACGAAAAGCCA
ATTCGAAGTACAATAAGAACAAACCACCCGCCCGGAGGAAAATCAAATCT
GATATTTTGATGTGAAAATTAAACAATTTATTAATCAGTCTTTTAATTTA
ATATTTAATTCAATAATTTTAGATTTTGATGTTGTTTAAATAATTGATTT
CAATTGATTTTTCTATGGATATTTTGTTTATTAGAATGGGTTTTTTTTAA
TTAATTATTTATGTTGGCATTGAATAAAATTTGATTAATTTCA
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protein sequence of SMED30022905-orf-1

>SMED30022905-orf-1 ID=SMED30022905-orf-1|Name=SMED30022905-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=570bp
MGEYILNFKTMKMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGD
TKVIDVTNKLIIPGGIDPSTNFNLSPNHRDILHNESMAALAGGTTTIITL
VKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNEDECVKSMETLAR
QFGINCFQMTIGNEINANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEEL
ITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAK
LVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPIRNDQD
AAIIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSM
LWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNP
VKTRTISALSQHLQNDTNIFEGISCQGVPEVVIVNGSVKFQLNEFIGNAT
GERIDLKINCQVVKDKMKRYECLREFGKMGITREISDNIGVASEIRTINN
PHKVIQKDIVTVDSKINPLKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKP
IRSTIRTNHPPGGKSNLIF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR011059Metal-dep_hydrolase_composite
IPR006680Amidohydro-rel
IPR032466Metal_Hydrolase
Vocabulary: molecular function
TermDefinition
GO:0016810hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0016787hydrolase activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006680Amidohydrolase-relatedPFAMPF01979Amidohydro_1coord: 59..436
e-value: 2.9E-13
score: 49.9
IPR011059Metal-dependent hydrolase, composite domain superfamilyGENE3DG3DSA:2.30.40.10coord: 11..462
e-value: 2.8E-136
score: 456.7
IPR011059Metal-dependent hydrolase, composite domain superfamilySUPERFAMILYSSF51338Composite domain of metallo-dependent hydrolasescoord: 9..447
NoneNo IPR availableGENE3DG3DSA:3.20.20.140coord: 62..424
e-value: 2.8E-136
score: 456.7
NoneNo IPR availablePANTHERPTHR11647AMINOHYDROLASEcoord: 8..473
NoneNo IPR availablePANTHERPTHR11647:SF1COLLAPSIN RESPONSE MEDIATOR PROTEINcoord: 8..473
IPR032466Metal-dependent hydrolaseSUPERFAMILYSSF51556Metallo-dependent hydrolasescoord: 62..381