Synaptotagmin VIa

Overview


Name	Synaptotagmin VIa
Smed ID	SMED30022848
Length (bp)	1451

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Synaptotagmin VIa (SMED30022848) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Synaptotagmin VIa (SMED30022848) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30022848

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30022848	h1SMcG0020287	dd_Smed_v4_12716_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30022848	h1SMcG0020287	dd_Smed_v4_12716_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
dorsal region of the epidermis	SMED30022848	h1SMcG0020287	dd_Smed_v4_12716_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Synaptotagmin VIa vs. Ensembl Human
Match: SYT9 (synaptotagmin 9 [Source:HGNC Symbol;Acc:HGNC:19265])

HSP 1 Score: 75.8702 bits (185), Expect = 1.910e-14
Identity = 39/110 (35.45%), Postives = 67/110 (60.91%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
            +  G ++F+L+Y+   + L V I +  NL  KD  GTSDPY  I   P  +    ++T+V  KTLNPV++ VF+ F   + +L+  ++H ++YD+D++  H+ +G+V  D
Sbjct:  187 KACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTK--HQTKVHRKTLNPVFDEVFL-FPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD 293

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BLAST of Synaptotagmin VIa vs. Ensembl Human
Match: RPH3A (rabphilin 3A [Source:HGNC Symbol;Acc:HGNC:17056])

HSP 1 Score: 77.0258 bits (188), Expect = 3.172e-14
Identity = 37/112 (33.04%), Postives = 57/112 (50.89%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + F L Y+    +L+  I + K L   D  G +DPY  +   P        +T+    T NP+WN   V+   T E++ R  + I++ D DK+G +E +GE  + LKKL
Sbjct:  393 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 504

HSP 2 Score: 57.3806 bits (137), Expect = 3.984e-8
Identity = 31/93 (33.33%), Postives = 48/93 (51.61%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWD 551
            G I   L Y  Q   L V I +  +L   D  G SDP+  +   P       +KT++K KTLNP +N  F F++  H +L +  + I+++D+D
Sbjct:  552 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEF-FYDIKHSDLAKKSLDISVWDYD 643

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Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + F L Y+    +L+  I + K L   D  G +DPY  +   P        +T+    T NP+WN   V+   T E++ R  + I++ D DK+G +E +GE  + LKKL
Sbjct:  393 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 504

HSP 2 Score: 57.3806 bits (137), Expect = 3.984e-8
Identity = 31/93 (33.33%), Postives = 48/93 (51.61%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWD 551
            G I   L Y  Q   L V I +  +L   D  G SDP+  +   P       +KT++K KTLNP +N  F F++  H +L +  + I+++D+D
Sbjct:  552 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEF-FYDIKHSDLAKKSLDISVWDYD 643

[Close]

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + F L Y+    +L+  I + K L   D  G +DPY  +   P        +T+    T NP+WN   V+   T E++ R  + I++ D DK+G +E +GE  + LKKL
Sbjct:  393 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 504

HSP 2 Score: 57.3806 bits (137), Expect = 3.984e-8
Identity = 31/93 (33.33%), Postives = 48/93 (51.61%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWD 551
            G I   L Y  Q   L V I +  +L   D  G SDP+  +   P       +KT++K KTLNP +N  F F++  H +L +  + I+++D+D
Sbjct:  552 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEF-FYDIKHSDLAKKSLDISVWDYD 643

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Human
Match: RPH3A (rabphilin 3A [Source:HGNC Symbol;Acc:HGNC:17056])

HSP 1 Score: 76.6406 bits (187), Expect = 3.734e-14
Identity = 37/112 (33.04%), Postives = 57/112 (50.89%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + F L Y+    +L+  I + K L   D  G +DPY  +   P        +T+    T NP+WN   V+   T E++ R  + I++ D DK+G +E +GE  + LKKL
Sbjct:  389 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 500

HSP 2 Score: 57.3806 bits (137), Expect = 4.372e-8
Identity = 31/93 (33.33%), Postives = 48/93 (51.61%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWD 551
            G I   L Y  Q   L V I +  +L   D  G SDP+  +   P       +KT++K KTLNP +N  F F++  H +L +  + I+++D+D
Sbjct:  548 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEF-FYDIKHSDLAKKSLDISVWDYD 639

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BLAST of Synaptotagmin VIa vs. Ensembl Celegans
Match: snt-1 (Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:P34693])

HSP 1 Score: 65.4698 bits (158), Expect = 3.078e-11
Identity = 39/112 (34.82%), Postives = 60/112 (53.57%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG I + L Y+ Q   L V + Q ++L G D  GTSDPY  +   P  +     +T+V  KTLNPV+N  F+ F     E+    +   +YD+D++  H+ +G+V   L K+
Sbjct:  160 LGRIQYKLDYDFQQGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKK--KVETKVHRKTLNPVFNETFI-FKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKI 268

HSP 2 Score: 55.0694 bits (131), Expect = 6.054e-8
Identity = 40/112 (35.71%), Postives = 55/112 (49.11%), Query Frame = 3

Query:  249 DPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            D   ++ LG I F LRY      L V I + KNL   D  G SDPY  I      +     KT +K  TLNP +N  F  F    E++ +  + IT+ D+DK G ++A+G  
Sbjct:  286 DKEAEKSLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIVLMQGGKRLKKKKTSIKKCTLNPYYNESFS-FEVPFEQIQKVSLMITVMDYDKLGSNDAIGRC 396

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BLAST of Synaptotagmin VIa vs. Ensembl Celegans
Match: snt-1 (Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:P34693])

HSP 1 Score: 65.0846 bits (157), Expect = 4.072e-11
Identity = 39/112 (34.82%), Postives = 60/112 (53.57%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG I + L Y+ Q   L V + Q ++L G D  GTSDPY  +   P  +     +T+V  KTLNPV+N  F+ F     E+    +   +YD+D++  H+ +G+V   L K+
Sbjct:  160 LGRIQYKLDYDFQQGQLTVTVIQAEDLPGMDMSGTSDPYVKLYLLPEKKK--KVETKVHRKTLNPVFNETFI-FKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKI 268

HSP 2 Score: 55.4546 bits (132), Expect = 4.392e-8
Identity = 42/116 (36.21%), Postives = 59/116 (50.86%), Query Frame = 3

Query:  249 DPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDD----WLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            D   ++ LG I F LRY      L V I + KNL   D  G SDPY  ++    F +D       KT +K KTLNP +N  FVF      ++ +  + IT+ D+DK G ++A+G  
Sbjct:  286 DKEAEKSLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKLEM---FGEDRKRLKKKKTNIKRKTLNPYFNESFVFDKLPLHKMKKVSLMITVMDYDKLGSNDAIGRC 398

HSP 3 Score: 49.2914 bits (116), Expect = 4.375e-6
Identity = 47/161 (29.19%), Postives = 74/161 (45.96%), Query Frame = 3

Query:  945 IEIKKNLQALPNSRSA---YGEILVSLDYVIRNRTLNVKIIKARNMIDPTKRALV-PYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPL-KVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLI 1412
            IE  K++   P+ + A    G+I  SL YV     L V I++A+N+       L  PY  L     G DR++ K       R  T  P +NE F   K+P  K+K+ ++ I V     +    +D +G   LG     A+  H+++ L +  +PI  WH +
Sbjct:  274 IEEWKDIAPPPDDKEAEKSLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKLE--MFGEDRKRLKKKKTNIKR-KTLNPYFNESFVFDKLPLHKMKKVSLMITVMDY--DKLGSNDAIGRCLLGCNGTGAELRHWMDMLASPRRPIAQWHTL 429

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BLAST of Synaptotagmin VIa vs. Ensembl Celegans
Match: snt-3 (SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5])

HSP 1 Score: 62.3882 bits (150), Expect = 1.303e-10
Identity = 35/112 (31.25%), Postives = 60/112 (53.57%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + + L Y+    +L V I Q + L   D  GTSDPY  +   P  +     +T+V+ K+LNPV+N  F  F     E+    + + ++D+D++G H+ +G++   L K+
Sbjct:   16 LGRLQYKLDYDFDKNSLTVVIIQAEELPAMDLGGTSDPYVKLFLLPDKKKKL--QTKVQRKSLNPVFNESFT-FKIPFNEIGGQTLVLNVFDFDRFGKHDQIGQISIPLGKV 124

HSP 2 Score: 55.4546 bits (132), Expect = 2.561e-8
Identity = 40/105 (38.10%), Postives = 57/105 (54.29%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            LG +   LRY      L V + + KNL   D  G SDPY  I      +     KT +KMKTLNP +N  F F + T E++ R  +H+T+ D+D+ G +E +G+V
Sbjct:  144 LGEVCLALRYVPNKNKLSVVVMECKNLKKMDVLGLSDPYVKIYLMMGTKRLEKKKTTIKMKTLNPYYNESFSF-DVTSEKMQRVHLHVTVSDYDRVGSNERIGQV 247

[Close]

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + + L Y+    +L V I Q + L   D  GTSDPY  +   P  +     +T+V+ K+LNPV+N  F  F     E+    + + ++D+D++G H+ +G++   L K+
Sbjct:   16 LGRLQYKLDYDFDKNSLTVVIIQAEELPAMDLGGTSDPYVKLFLLPDKKKKL--QTKVQRKSLNPVFNESFT-FKIPFNEIGGQTLVLNVFDFDRFGKHDQIGQISIPLGKV 124

HSP 2 Score: 55.4546 bits (132), Expect = 2.561e-8
Identity = 40/105 (38.10%), Postives = 57/105 (54.29%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            LG +   LRY      L V + + KNL   D  G SDPY  I      +     KT +KMKTLNP +N  F F + T E++ R  +H+T+ D+D+ G +E +G+V
Sbjct:  144 LGEVCLALRYVPNKNKLSVVVMECKNLKKMDVLGLSDPYVKIYLMMGTKRLEKKKTTIKMKTLNPYYNESFSF-DVTSEKMQRVHLHVTVSDYDRVGSNERIGQV 247

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BLAST of Synaptotagmin VIa vs. Ensembl Celegans
Match: rbf-1 (Rabphilin-1 [Source:UniProtKB/Swiss-Prot;Acc:P41885])

HSP 1 Score: 63.929 bits (154), Expect = 1.844e-10
Identity = 42/128 (32.81%), Postives = 63/128 (49.22%), Query Frame = 3

Query:  249 DPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEEKE 632
            +PG    LG I   L Y    K LK+++ + KNL   D  G SDPY      P         ++   KTLNP WN    ++  T ++ ++  + +T+ D D+ G  + LGE    LKKL+  D+E K+
Sbjct:  746 EPG---SLGSITLTLTYHSADKKLKMHLIRAKNLKAMDSNGFSDPYVKFHLLPGNTKATKLTSKTIEKTLNPEWNEEMSYYGITEDDKEKKILRVTVLDRDRIGS-DFLGETRIALKKLN--DNEMKK 867

HSP 2 Score: 59.6918 bits (143), Expect = 3.599e-9
Identity = 35/99 (35.35%), Postives = 49/99 (49.49%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHE 569
            G I+  L+Y +Q  +L +NI +   LVG D  G SDPY  +   P        KT  K +TLNP WN    F     ++L +  + I +YD D  G H+
Sbjct:  891 GKINVGLQYNIQQGSLFININRCVELVGMDSTGFSDPYCKVSLTPITSKAHRAKTSTKKRTLNPEWNEQLQFV-VPFKDLPKKTLQIGVYDHD-LGKHD 987

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BLAST of Synaptotagmin VIa vs. Ensembl Fly
Match: Syt7 (gene:FBgn0039900 transcript:FBtr0305658)

HSP 1 Score: 85.1149 bits (209), Expect = 1.026e-17
Identity = 43/121 (35.54%), Postives = 70/121 (57.85%), Query Frame = 3

Query:  243 NIDPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + DP   + +G IHF L Y+ Q  TL + + QGK L  KD  GTSDPY  +   P  +     +T++K +TLNP WN  F F  F  ++L    +H+ ++D+D++   +++GEV+  L ++
Sbjct:  141 STDP--SENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHR--LETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQV 257

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BLAST of Synaptotagmin VIa vs. Ensembl Fly
Match: Syt7 (gene:FBgn0039900 transcript:FBtr0089139)

HSP 1 Score: 83.5741 bits (205), Expect = 1.242e-17
Identity = 43/121 (35.54%), Postives = 70/121 (57.85%), Query Frame = 3

Query:  243 NIDPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + DP   + +G IHF L Y+ Q  TL + + QGK L  KD  GTSDPY  +   P  +     +T++K +TLNP WN  F F  F  ++L    +H+ ++D+D++   +++GEV+  L ++
Sbjct:    8 STDPS--ENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHR--LETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQV 124

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BLAST of Synaptotagmin VIa vs. Ensembl Fly
Match: Syt7 (gene:FBgn0039900 transcript:FBtr0089134)

HSP 1 Score: 84.3445 bits (207), Expect = 1.389e-17
Identity = 43/121 (35.54%), Postives = 70/121 (57.85%), Query Frame = 3

Query:  243 NIDPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + DP   + +G IHF L Y+ Q  TL + + QGK L  KD  GTSDPY  +   P  +     +T++K +TLNP WN  F F  F  ++L    +H+ ++D+D++   +++GEV+  L ++
Sbjct:  141 STDP--SENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHR--LETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQV 257

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Fly
Match: Syt7 (gene:FBgn0039900 transcript:FBtr0343990)

HSP 1 Score: 84.7297 bits (208), Expect = 2.438e-17
Identity = 41/115 (35.65%), Postives = 67/115 (58.26%), Query Frame = 3

Query:  261 DQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
             + +G IHF L Y+ Q  TL + + QGK L  KD  GTSDPY  +   P  +     +T++K +TLNP WN  F F  F  ++L    +H+ ++D+D++   +++GEV+  L ++
Sbjct:  145 SENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHR--LETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQV 257

HSP 2 Score: 49.2914 bits (116), Expect = 5.592e-6
Identity = 35/118 (29.66%), Postives = 55/118 (46.61%), Query Frame = 3

Query:  291 LRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWL--YKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEEKEED 638
            L Y      L + + + +NL  KD  G SDPY  +K   +F D  +   KT +   TLNPV+N  F  FN   E++    + + + D+D  G +E +G +    K   G    +  +D
Sbjct:  284 LCYHPSNSILTLTLIKARNLKAKDINGKSDPY--VKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFS-FNVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASETKHWQD 398

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Fly
Match: Syt7 (gene:FBgn0039900 transcript:FBtr0089137)

HSP 1 Score: 84.7297 bits (208), Expect = 2.438e-17
Identity = 41/115 (35.65%), Postives = 67/115 (58.26%), Query Frame = 3

Query:  261 DQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
             + +G IHF L Y+ Q  TL + + QGK L  KD  GTSDPY  +   P  +     +T++K +TLNP WN  F F  F  ++L    +H+ ++D+D++   +++GEV+  L ++
Sbjct:  145 SENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHR--LETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQV 257

HSP 2 Score: 49.2914 bits (116), Expect = 5.592e-6
Identity = 35/118 (29.66%), Postives = 55/118 (46.61%), Query Frame = 3

Query:  291 LRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWL--YKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEEKEED 638
            L Y      L + + + +NL  KD  G SDPY  +K   +F D  +   KT +   TLNPV+N  F  FN   E++    + + + D+D  G +E +G +    K   G    +  +D
Sbjct:  284 LCYHPSNSILTLTLIKARNLKAKDINGKSDPY--VKVWLQFGDKRVEKRKTPIFTCTLNPVFNESFS-FNVPWEKIRECSLDVMVMDFDNIGRNELIGRILLAGKNGSGASETKHWQD 398

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Zebrafish
Match: syt7a (synaptotagmin VIIa [Source:ZFIN;Acc:ZDB-GENE-090601-5])

HSP 1 Score: 79.7221 bits (195), Expect = 2.359e-15
Identity = 42/116 (36.21%), Postives = 66/116 (56.90%), Query Frame = 3

Query:  258 IDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + + LG I F L Y  Q  TL V I +G++L  KD  GTSDP+  I   P  +     +T+VK K LNP WN  F+F  F +E++    +++ + D+D++  ++ +GEV   L K+
Sbjct:  336 VSEKLGRIQFSLGYSFQDTTLTVKILKGQDLPAKDFSGTSDPFVKIYLLPDRKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVRERTLYLQVLDYDRFSRNDPIGEVSIPLNKV 449

HSP 2 Score: 60.077 bits (144), Expect = 3.458e-9
Identity = 47/157 (29.94%), Postives = 75/157 (47.77%), Query Frame = 3

Query:  957 KNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM----IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIR 1415
            K+L+   +   + G++LVSL Y     T+ V IIKARN+    I  T    V   ++ H     +++KT +I R         PV+NE FP  VP   L++T + I V      S  ++D +G I L  K+ P +  H+ + L      +  WH ++
Sbjct:  459 KDLKPCSDGSGSRGDLLVSLCYNPTANTITVNIIKARNLKAMDIGGTSDPYVKVWLM-HKDKRVEKKKTVTIKRCL------NPVFNESFPFDVPAHVLRETTIIITVMDKDRLS--RNDVIGKIYLSWKSGPGEVKHWKDMLSRPRTNVAQWHALK 606

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Zebrafish
Match: syt7a (synaptotagmin VIIa [Source:ZFIN;Acc:ZDB-GENE-090601-5])

HSP 1 Score: 77.7962 bits (190), Expect = 4.846e-15
Identity = 42/116 (36.21%), Postives = 66/116 (56.90%), Query Frame = 3

Query:  258 IDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + + LG I F L Y  Q  TL V I +G++L  KD  GTSDP+  I   P  +     +T+VK K LNP WN  F+F  F +E++    +++ + D+D++  ++ +GEV   L K+
Sbjct:  110 VSEKLGRIQFSLGYSFQDTTLTVKILKGQDLPAKDFSGTSDPFVKIYLLPDRKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVRERTLYLQVLDYDRFSRNDPIGEVSIPLNKV 223

HSP 2 Score: 60.4622 bits (145), Expect = 1.652e-9
Identity = 47/157 (29.94%), Postives = 75/157 (47.77%), Query Frame = 3

Query:  957 KNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM----IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIR 1415
            K+L+   +   + G++LVSL Y     T+ V IIKARN+    I  T    V   ++ H     +++KT +I R         PV+NE FP  VP   L++T + I V      S  ++D +G I L  K+ P +  H+ + L      +  WH ++
Sbjct:  233 KDLKPCSDGSGSRGDLLVSLCYNPTANTITVNIIKARNLKAMDIGGTSDPYVKVWLM-HKDKRVEKKKTVTIKRCL------NPVFNESFPFDVPAHVLRETTIIITVMDKDRLS--RNDVIGKIYLSWKSGPGEVKHWKDMLSRPRTNVAQWHALK 380

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Zebrafish
Match: syt9a (synaptotagmin IXa [Source:ZFIN;Acc:ZDB-GENE-031002-18])

HSP 1 Score: 78.1814 bits (191), Expect = 6.648e-15
Identity = 39/109 (35.78%), Postives = 65/109 (59.63%), Query Frame = 3

Query:  267 GLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
              G +HF+L+Y+   + L V I + ++L  KD  GTSDPY  I   P  +    ++T+V  KTLNPV++ VF  F   + +L   ++H ++YD+D++  H+ +G+V  D
Sbjct:  256 SCGRLHFILKYDCDLEQLIVKIHRAQDLPAKDFSGTSDPYVKIYLLPDRKTK--HQTKVHRKTLNPVFDEVF-LFPVAYADLPTRKLHFSVYDFDRFSRHDIIGQVVVD 361

HSP 2 Score: 56.9954 bits (136), Expect = 3.452e-8
Identity = 33/103 (32.04%), Postives = 50/103 (48.54%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALG 578
            LG + F L Y      L + + + +NL   D  G SDPY  +      R     KT  K  TLNPV+N   V F+   E +D+  + + + D+D+ G +E +G
Sbjct:  389 LGDLMFSLCYLPTAGRLTITMIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIV-FDVPPENIDQISLLVAVMDYDRVGHNEVIG 490

HSP 3 Score: 54.299 bits (129), Expect = 2.027e-7
Identity = 44/162 (27.16%), Postives = 79/162 (48.77%), Query Frame = 3

Query:  927 VNVIRRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM--IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWH 1406
            V+  R  ++ +++Q + +     G+++ SL Y+     L + +IKARN+  +D T  A  PY  +  +  G   +K K    TS +  T  PV+NE     VPP+ + Q ++ + V     +    ++ +G+ R+G       + H+ E L    KPI +WH
Sbjct:  367 VDFPRETKLCRDIQYVSSDNVDLGDLMFSLCYLPTAGRLTITMIKARNLKAMDITG-ASDPYVKVSLMCDGRRLKKRK----TSTKRNTLNPVYNEAIVFDVPPENIDQISLLVAVMD--YDRVGHNEVIGVCRVGNDAEGLGREHWNEMLTYPRKPIAHWH 521

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Zebrafish
Match: syt7b (synaptotagmin VIIb [Source:ZFIN;Acc:ZDB-GENE-090601-6])

HSP 1 Score: 77.7962 bits (190), Expect = 8.492e-15
Identity = 40/112 (35.71%), Postives = 65/112 (58.04%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG I F + Y  Q  TL V I +G++L  KD  GTSDP+  +   P  +     +T+VK K LNP WN  F+F  F +E++ +  +++ + D+D++  ++ +GEV   L K+
Sbjct:  387 LGRIQFSVGYSFQDSTLTVKILKGQDLPAKDFSGTSDPFVKLYLLPDKKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVVQRTLYLQVLDYDRFSRNDPIGEVSIPLNKV 496

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Zebrafish
Match: syt7b (synaptotagmin VIIb [Source:ZFIN;Acc:ZDB-GENE-090601-6])

HSP 1 Score: 77.0258 bits (188), Expect = 1.246e-14
Identity = 40/116 (34.48%), Postives = 67/116 (57.76%), Query Frame = 3

Query:  258 IDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + + LG I F + Y  Q  TL V I +G++L  KD  GTSDP+  +   P  +     +T+VK K LNP WN  F+F  F +E++ +  +++ + D+D++  ++ +GEV   L K+
Sbjct:  217 VCEKLGRIQFSVGYSFQDSTLTVKILKGQDLPAKDFSGTSDPFVKLYLLPDKKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVVQRTLYLQVLDYDRFSRNDPIGEVSIPLNKV 330

HSP 2 Score: 58.151 bits (139), Expect = 1.316e-8
Identity = 47/175 (26.86%), Postives = 80/175 (45.71%), Query Frame = 3

Query:  909 EENIPT--VNVIRRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM----IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIR 1415
            E +IP   V ++    + K L+   +   + G++LVSL Y      + V IIKARN+    I  T    V   ++       +++K     +T        PV+NE FP  VP   L++T + I V      S  ++D +G I L  K+ PA+  H+ + + +    +  WH ++
Sbjct:  322 EVSIPLNKVELVPMQTLWKELKPCSDGSGSRGDLLVSLCYNPTANIITVSIIKARNLKAMDIGGTSDPYVKVWLM-------NKDKRVEKKKTVVMKRCLNPVFNESFPFDVPAHVLRETTIVITVMDKDRLS--RNDVIGKIYLSWKSGPAEVKHWKDMMSHPRTAVAQWHALK 487

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Xenopus
Match: RPH3A (rabphilin 3A [Source:NCBI gene;Acc:100487950])

HSP 1 Score: 78.1814 bits (191), Expect = 1.090e-14
Identity = 39/112 (34.82%), Postives = 57/112 (50.89%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + F L Y+ +  +L   I + K L   D  G +DPY  +   P        +T+    T NP+WN   V+   T EEL R  + I++ D DK+G +E +GE  + LKKL
Sbjct:  393 LGSLEFSLFYDQENNSLHCGIIKAKGLKPMDSNGLADPYVKLHLLPGASKANKLRTKTLRNTRNPIWNETLVYHGITDEELQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 504

HSP 2 Score: 55.4546 bits (132), Expect = 1.663e-7
Identity = 30/93 (32.26%), Postives = 47/93 (50.54%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWD 551
            G I   L Y  Q   L V I +  +L   D  G SDP+  +   P        KT++K KTLNP +N  F F+   H +L + ++ ++++D+D
Sbjct:  551 GKILVSLMYNTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKNKTQIKKKTLNPEFNEEF-FYEIKHSDLAKKQLDVSVWDYD 642

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Xenopus
Match: RPH3A (rabphilin 3A [Source:NCBI gene;Acc:100487950])

HSP 1 Score: 76.2554 bits (186), Expect = 1.838e-14
Identity = 39/112 (34.82%), Postives = 57/112 (50.89%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + F L Y+ +  +L   I + K L   D  G +DPY  +   P        +T+    T NP+WN   V+   T EEL R  + I++ D DK+G +E +GE  + LKKL
Sbjct:   89 LGSLEFSLFYDQENNSLHCGIIKAKGLKPMDSNGLADPYVKLHLLPGASKANKLRTKTLRNTRNPIWNETLVYHGITDEELQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 200

HSP 2 Score: 54.6842 bits (130), Expect = 2.012e-7
Identity = 30/93 (32.26%), Postives = 47/93 (50.54%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWD 551
            G I   L Y  Q   L V I +  +L   D  G SDP+  +   P        KT++K KTLNP +N  F F+   H +L + ++ ++++D+D
Sbjct:  228 GKILVSLMYNTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKNKTQIKKKTLNPEFNEEF-FYEIKHSDLAKKQLDVSVWDYD 319

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Xenopus
Match: wnt6 (Wnt family member 6 [Source:Xenbase;Acc:XB-GENE-486077])

HSP 1 Score: 77.0258 bits (188), Expect = 1.879e-14
Identity = 39/109 (35.78%), Postives = 60/109 (55.05%), Query Frame = 3

Query:  267 GLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
              G I F+LRY   ++ L V I +   L  KD  G SDPY  +   P  +    ++T+V  KTLNP++N  F  FN    EL   ++H ++YD+D++  H+ +G+V  D
Sbjct:  247 SCGRISFILRYAYNSEQLVVKILKALELPAKDANGFSDPYVKMYLLPDRKKK--FQTKVHRKTLNPIFNETF-HFNVPFNELQNRKLHFSIYDFDRFSRHDLIGQVVLD 352

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Xenopus
Match: RPH3A (rabphilin 3A [Source:NCBI gene;Acc:100487950])

HSP 1 Score: 77.411 bits (189), Expect = 1.897e-14
Identity = 39/112 (34.82%), Postives = 57/112 (50.89%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + F L Y+ +  +L   I + K L   D  G +DPY  +   P        +T+    T NP+WN   V+   T EEL R  + I++ D DK+G +E +GE  + LKKL
Sbjct:  352 LGSLEFSLFYDQENNSLHCGIIKAKGLKPMDSNGLADPYVKLHLLPGASKANKLRTKTLRNTRNPIWNETLVYHGITDEELQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 463

HSP 2 Score: 55.0694 bits (131), Expect = 2.119e-7
Identity = 30/93 (32.26%), Postives = 47/93 (50.54%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWD 551
            G I   L Y  Q   L V I +  +L   D  G SDP+  +   P        KT++K KTLNP +N  F F+   H +L + ++ ++++D+D
Sbjct:  510 GKILVSLMYNTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKNKTQIKKKTLNPEFNEEF-FYEIKHSDLAKKQLDVSVWDYD 601

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Xenopus
Match: RPH3A (rabphilin 3A [Source:NCBI gene;Acc:100487950])

HSP 1 Score: 77.0258 bits (188), Expect = 2.321e-14
Identity = 39/112 (34.82%), Postives = 57/112 (50.89%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + F L Y+ +  +L   I + K L   D  G +DPY  +   P        +T+    T NP+WN   V+   T EEL R  + I++ D DK+G +E +GE  + LKKL
Sbjct:  282 LGSLEFSLFYDQENNSLHCGIIKAKGLKPMDSNGLADPYVKLHLLPGASKANKLRTKTLRNTRNPIWNETLVYHGITDEELQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 393

HSP 2 Score: 54.6842 bits (130), Expect = 2.263e-7
Identity = 30/93 (32.26%), Postives = 47/93 (50.54%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWD 551
            G I   L Y  Q   L V I +  +L   D  G SDP+  +   P        KT++K KTLNP +N  F F+   H +L + ++ ++++D+D
Sbjct:  440 GKILVSLMYNTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKNKTQIKKKTLNPEFNEEF-FYEIKHSDLAKKQLDVSVWDYD 531

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Mouse
Match: Syt9 (synaptotagmin IX [Source:MGI Symbol;Acc:MGI:1926373])

HSP 1 Score: 75.0998 bits (183), Expect = 4.880e-14
Identity = 39/110 (35.45%), Postives = 67/110 (60.91%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
            +  G ++F+L+Y+   + L V I +  NL  KD  GTSDPY  I   P  +    ++T+V  KTLNPV++ VF+ F   + +L+  ++H ++YD+D++  H+ +G+V  D
Sbjct:  219 KACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTK--HQTKVHRKTLNPVFDEVFL-FPVHYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD 325

HSP 2 Score: 60.4622 bits (145), Expect = 2.263e-9
Identity = 44/144 (30.56%), Postives = 68/144 (47.22%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALG--EVYYDLKKLHGKDHEEKEEDQPNEYAESLNVEKLSIKEW 695
            LG + F L Y      L + I + +NL   D  G SDPY  +      R     KT  K  TLNPV+N   V F+   E +D+  + I + D+D+ G +E +G  +V  + ++L G+DH          ++E L+  +  I  W
Sbjct:  353 LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIV-FDVPPESIDQIHLSIAVMDYDRVGHNEVIGVCQVGNEAERL-GRDH----------WSEMLSYPRKPIAHW 484

HSP 3 Score: 56.225 bits (134), Expect = 5.846e-8
Identity = 46/158 (29.11%), Postives = 76/158 (48.10%), Query Frame = 3

Query:  939 RRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM--IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWH 1406
            R   + K+++ + N     GE++ SL Y+     L + IIKARN+  +D T  A  PY  +  +  G   +K K    TS +  T  PV+NE     VPP+ + Q  + I V     +    ++ +G+ ++G +     + H+ E L    KPI +WH
Sbjct:  335 RECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITG-ASDPYVKVSLMCDGRRLKKRK----TSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVM--DYDRVGHNEVIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWH 485

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Mouse
Match: Syt7 (synaptotagmin VII [Source:MGI Symbol;Acc:MGI:1859545])

HSP 1 Score: 73.9442 bits (180), Expect = 1.137e-13
Identity = 39/114 (34.21%), Postives = 64/114 (56.14%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + LG I F + Y  Q  TL V + + + L  KD  GTSDP+  I   P  +     +T+VK K LNP WN  F+F  F +E++ +  +++ + D+D++  ++ +GEV   L K+
Sbjct:  210 ENLGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKV 321

HSP 2 Score: 56.9954 bits (136), Expect = 3.027e-8
Identity = 42/157 (26.75%), Postives = 77/157 (49.04%), Query Frame = 3

Query:  957 KNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM----IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIR 1415
            K+L+   +   + GE+L+SL Y     ++ V IIKARN+    I  T     PY  +  ++    ++K     +T  +     P++NE F   +P +KL++T + I V      S  ++D +G I L  K+ P +  H+ + +    +P+  WH ++
Sbjct:  331 KDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSD---PYVKVWLMY----KDKRVEKKKTVTKKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLS--RNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLK 478

HSP 3 Score: 52.7582 bits (125), Expect = 7.781e-7
Identity = 36/113 (31.86%), Postives = 55/113 (48.67%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHG 611
            G +   L Y     ++ VNI + +NL   D  GTSDPY  +    + +     KT  K + LNP++N  F  F+   E+L    I IT+ D DK   ++ +G++Y   K   G
Sbjct:  344 GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFA-FDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPG 455

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Mouse
Match: Syt7 (synaptotagmin VII [Source:MGI Symbol;Acc:MGI:1859545])

HSP 1 Score: 74.3294 bits (181), Expect = 1.146e-13
Identity = 39/112 (34.82%), Postives = 63/112 (56.25%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG I F + Y  Q  TL V + + + L  KD  GTSDP+  I   P  +     +T+VK K LNP WN  F+F  F +E++ +  +++ + D+D++  ++ +GEV   L K+
Sbjct:  376 LGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKV 485

HSP 2 Score: 56.6102 bits (135), Expect = 4.977e-8
Identity = 42/157 (26.75%), Postives = 77/157 (49.04%), Query Frame = 3

Query:  957 KNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM----IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIR 1415
            K+L+   +   + GE+L+SL Y     ++ V IIKARN+    I  T     PY  +  ++    ++K     +T  +     P++NE F   +P +KL++T + I V      S  ++D +G I L  K+ P +  H+ + +    +P+  WH ++
Sbjct:  495 KDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSD---PYVKVWLMY----KDKRVEKKKTVTKKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLS--RNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLK 642

HSP 3 Score: 52.7582 bits (125), Expect = 8.739e-7
Identity = 36/114 (31.58%), Postives = 56/114 (49.12%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGK 614
            G +   L Y     ++ VNI + +NL   D  GTSDPY  +    + +     KT  K + LNP++N  F  F+   E+L    I IT+ D DK   ++ +G++Y   K   G+
Sbjct:  508 GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFA-FDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGE 620

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Mouse
Match: Syt7 (synaptotagmin VII [Source:MGI Symbol;Acc:MGI:1859545])

HSP 1 Score: 73.559 bits (179), Expect = 1.154e-13
Identity = 39/114 (34.21%), Postives = 64/114 (56.14%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + LG I F + Y  Q  TL V + + + L  KD  GTSDP+  I   P  +     +T+VK K LNP WN  F+F  F +E++ +  +++ + D+D++  ++ +GEV   L K+
Sbjct:  134 ENLGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKV 245

HSP 2 Score: 56.9954 bits (136), Expect = 2.419e-8
Identity = 42/157 (26.75%), Postives = 77/157 (49.04%), Query Frame = 3

Query:  957 KNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM----IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIR 1415
            K+L+   +   + GE+L+SL Y     ++ V IIKARN+    I  T     PY  +  ++    ++K     +T  +     P++NE F   +P +KL++T + I V      S  ++D +G I L  K+ P +  H+ + +    +P+  WH ++
Sbjct:  255 KDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSD---PYVKVWLMY----KDKRVEKKKTVTKKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLS--RNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLK 402

HSP 3 Score: 51.9878 bits (123), Expect = 9.909e-7
Identity = 36/114 (31.58%), Postives = 56/114 (49.12%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGK 614
            G +   L Y     ++ VNI + +NL   D  GTSDPY  +    + +     KT  K + LNP++N  F  F+   E+L    I IT+ D DK   ++ +G++Y   K   G+
Sbjct:  268 GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFA-FDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGE 380

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Mouse
Match: Syt7 (synaptotagmin VII [Source:MGI Symbol;Acc:MGI:1859545])

HSP 1 Score: 74.3294 bits (181), Expect = 1.205e-13
Identity = 39/112 (34.82%), Postives = 63/112 (56.25%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG I F + Y  Q  TL V + + + L  KD  GTSDP+  I   P  +     +T+VK K LNP WN  F+F  F +E++ +  +++ + D+D++  ++ +GEV   L K+
Sbjct:  253 LGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKV 362

HSP 2 Score: 56.9954 bits (136), Expect = 3.079e-8
Identity = 42/157 (26.75%), Postives = 77/157 (49.04%), Query Frame = 3

Query:  957 KNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM----IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIR 1415
            K+L+   +   + GE+L+SL Y     ++ V IIKARN+    I  T     PY  +  ++    ++K     +T  +     P++NE F   +P +KL++T + I V      S  ++D +G I L  K+ P +  H+ + +    +P+  WH ++
Sbjct:  372 KDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSD---PYVKVWLMY----KDKRVEKKKTVTKKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLS--RNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLK 519

HSP 3 Score: 52.373 bits (124), Expect = 8.414e-7
Identity = 36/114 (31.58%), Postives = 56/114 (49.12%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGK 614
            G +   L Y     ++ VNI + +NL   D  GTSDPY  +    + +     KT  K + LNP++N  F  F+   E+L    I IT+ D DK   ++ +G++Y   K   G+
Sbjct:  385 GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFA-FDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGE 497

[Close]

BLAST of Synaptotagmin VIa vs. UniProt/SwissProt
Match: sp|P24507|SY63_DIPOM (Synaptotagmin-C OS=Diplobatis ommata OX=1870830 GN=P65-C PE=2 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 2.394e-14
Identity = 41/108 (37.96%), Postives = 62/108 (57.41%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
             G I+F+LRY   T+ L V I +  +L  KD  G SDPY  I   P  +    ++T+V  KTLNP++N  F  FN    EL   ++H ++YD+D++  H+ +G+V  D
Sbjct:  237 CGRINFMLRYTYTTEQLVVKILKALDLPAKDANGFSDPYVKIYLLPDRKKK--FQTKVHRKTLNPIFNETFQ-FNVPFNELQNRKLHFSVYDFDRFSRHDLIGQVVLD 341

HSP 2 Score: 55.8398 bits (133), Expect = 6.163e-7
Identity = 35/103 (33.98%), Postives = 49/103 (47.57%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALG 578
            LG I+F L Y      L + I +  NL   D  G SDPY         R     KT +K  TLNPV+N   V F+  +E ++   + I + D+D  G +E +G
Sbjct:  369 LGEINFSLCYLPTAGRLTITIIKATNLKAMDLTGFSDPYVKASLICDERRLKKRKTSIKKNTLNPVYNEALV-FDIPNENMEHVNVIIAVMDYDCIGHNEVIG 470

HSP 3 Score: 55.4546 bits (132), Expect = 7.665e-7
Identity = 47/155 (30.32%), Postives = 77/155 (49.68%), Query Frame = 3

Query:  984 RSAYGEILVSLDYVIRNRTLNVKIIKARNM--IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIRK*KVIRSSL 1442
            ++  GEI  SL Y+     L + IIKA N+  +D T  +  PY  ++   I ++R   K   +TS +  T  PV+NE     +P + ++   V I V     +    ++ +G+ R+G  T    + H+ E L N  KPIE WH + + KV+ S +
Sbjct:  366 KADLGEINFSLCYLPTAGRLTITIIKATNLKAMDLTGFS-DPY--VKASLICDERRLKK--RKTSIKKNTLNPVYNEALVFDIPNENMEHVNVIIAVMDY--DCIGHNEVIGMCRVGNATDGPGREHWNEMLANPRKPIEQWHQLIEEKVMNSYM 513

[Close]

BLAST of Synaptotagmin VIa vs. UniProt/SwissProt
Match: sp|Q9Y2J0|RP3A_HUMAN (Rabphilin-3A OS=Homo sapiens OX=9606 GN=RPH3A PE=1 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 1.523e-13
Identity = 37/112 (33.04%), Postives = 57/112 (50.89%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + F L Y+    +L+  I + K L   D  G +DPY  +   P        +T+    T NP+WN   V+   T E++ R  + I++ D DK+G +E +GE  + LKKL
Sbjct:  393 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 504

HSP 2 Score: 57.3806 bits (137), Expect = 1.913e-7
Identity = 31/93 (33.33%), Postives = 48/93 (51.61%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWD 551
            G I   L Y  Q   L V I +  +L   D  G SDP+  +   P       +KT++K KTLNP +N  F F++  H +L +  + I+++D+D
Sbjct:  552 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEF-FYDIKHSDLAKKSLDISVWDYD 643

[Close]

BLAST of Synaptotagmin VIa vs. UniProt/SwissProt
Match: sp|Q86SS6|SYT9_HUMAN (Synaptotagmin-9 OS=Homo sapiens OX=9606 GN=SYT9 PE=1 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 2.350e-13
Identity = 39/110 (35.45%), Postives = 67/110 (60.91%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
            +  G ++F+L+Y+   + L V I +  NL  KD  GTSDPY  I   P  +    ++T+V  KTLNPV++ VF+ F   + +L+  ++H ++YD+D++  H+ +G+V  D
Sbjct:  219 KACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTK--HQTKVHRKTLNPVFDEVFL-FPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD 325

HSP 2 Score: 60.077 bits (144), Expect = 2.078e-8
Identity = 44/144 (30.56%), Postives = 68/144 (47.22%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALG--EVYYDLKKLHGKDHEEKEEDQPNEYAESLNVEKLSIKEW 695
            LG + F L Y      L + I + +NL   D  G SDPY  +      R     KT  K  TLNPV+N   V F+   E +D+  + I + D+D+ G +E +G  +V  + ++L G+DH          ++E L+  +  I  W
Sbjct:  353 LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIV-FDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERL-GRDH----------WSEMLSYPRKPIAHW 484

HSP 3 Score: 55.4546 bits (132), Expect = 6.169e-7
Identity = 46/158 (29.11%), Postives = 76/158 (48.10%), Query Frame = 3

Query:  939 RRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM--IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWH 1406
            R   + K+++ + N     GE++ SL Y+     L + IIKARN+  +D T  A  PY  +  +  G   +K K    TS +  T  PV+NE     VPP+ + Q  + I V     +    ++ +G+ ++G +     + H+ E L    KPI +WH
Sbjct:  335 RECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITG-ASDPYVKVSLMCDGRRLKKRK----TSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVM--DYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWH 485

[Close]

BLAST of Synaptotagmin VIa vs. UniProt/SwissProt
Match: sp|Q06846|RP3A_BOVIN (Rabphilin-3A OS=Bos taurus OX=9913 GN=RPH3A PE=1 SV=1)

HSP 1 Score: 76.2554 bits (186), Expect = 2.496e-13
Identity = 37/112 (33.04%), Postives = 56/112 (50.00%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            LG + F L Y+    +L   I + K L   D  G +DPY  +   P        +T+    T NP+WN   V+   T E++ R  + I++ D DK+G +E +GE  + LKKL
Sbjct:  403 LGALEFSLLYDQDNSSLHCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKL 514

HSP 2 Score: 57.7658 bits (138), Expect = 1.735e-7
Identity = 31/93 (33.33%), Postives = 48/93 (51.61%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWD 551
            G I   L Y  Q   L V I +  +L   D  G SDP+  +   P       +KT++K KTLNP +N  F F++  H +L +  + I+++D+D
Sbjct:  562 GKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEF-FYDIKHSDLAKKSLDISVWDYD 653

[Close]

BLAST of Synaptotagmin VIa vs. UniProt/SwissProt
Match: sp|Q9R0N9|SYT9_MOUSE (Synaptotagmin-9 OS=Mus musculus OX=10090 GN=Syt9 PE=1 SV=2)

HSP 1 Score: 75.0998 bits (183), Expect = 3.414e-13
Identity = 39/110 (35.45%), Postives = 67/110 (60.91%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
            +  G ++F+L+Y+   + L V I +  NL  KD  GTSDPY  I   P  +    ++T+V  KTLNPV++ VF+ F   + +L+  ++H ++YD+D++  H+ +G+V  D
Sbjct:  219 KACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTK--HQTKVHRKTLNPVFDEVFL-FPVHYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD 325

HSP 2 Score: 60.4622 bits (145), Expect = 1.583e-8
Identity = 44/144 (30.56%), Postives = 68/144 (47.22%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALG--EVYYDLKKLHGKDHEEKEEDQPNEYAESLNVEKLSIKEW 695
            LG + F L Y      L + I + +NL   D  G SDPY  +      R     KT  K  TLNPV+N   V F+   E +D+  + I + D+D+ G +E +G  +V  + ++L G+DH          ++E L+  +  I  W
Sbjct:  353 LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIV-FDVPPESIDQIHLSIAVMDYDRVGHNEVIGVCQVGNEAERL-GRDH----------WSEMLSYPRKPIAHW 484

HSP 3 Score: 56.225 bits (134), Expect = 4.089e-7
Identity = 46/158 (29.11%), Postives = 76/158 (48.10%), Query Frame = 3

Query:  939 RRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM--IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWH 1406
            R   + K+++ + N     GE++ SL Y+     L + IIKARN+  +D T  A  PY  +  +  G   +K K    TS +  T  PV+NE     VPP+ + Q  + I V     +    ++ +G+ ++G +     + H+ E L    KPI +WH
Sbjct:  335 RECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITG-ASDPYVKVSLMCDGRRLKKRK----TSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVM--DYDRVGHNEVIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWH 485

[Close]

BLAST of Synaptotagmin VIa vs. TrEMBL
Match: D7EJD0 (Synaptotagmin 1-like Protein OS=Tribolium castaneum OX=7070 GN=TcasGA2_TC002242 PE=4 SV=2)

HSP 1 Score: 83.9593 bits (206), Expect = 1.357e-15
Identity = 42/114 (36.84%), Postives = 68/114 (59.65%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + +G IHF L Y+ Q  TL + I QGK+L  KD  GTSDPY  +   P  +     +T++K +TLNP WN  F F  F  ++L    +H+ ++D+D++   +++GEV+  L ++
Sbjct:   23 ENVGQIHFSLEYDFQNTTLILRIIQGKDLPAKDLSGTSDPYVRVTLLPDKKHRL--ETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQV 134

[Close]

BLAST of Synaptotagmin VIa vs. TrEMBL
Match: D3TS75 (Synaptotagmin OS=Glossina morsitans morsitans OX=37546 PE=2 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 2.989e-15
Identity = 41/115 (35.65%), Postives = 68/115 (59.13%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLH 608
            + +G IHF L Y+ Q  +L + + QGK L  KD  GTSDPY  +   P  +     +T++K +TLNP WN  F F  F  ++L    +H+ ++D+D++   +++GEV+  L ++H
Sbjct:  151 ENVGQIHFSLEYDFQNTSLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHR--LETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQIH 263

[Close]

BLAST of Synaptotagmin VIa vs. TrEMBL
Match: U4UCS3 (C2 domain-containing protein OS=Dendroctonus ponderosae OX=77166 GN=D910_01135 PE=4 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 4.159e-15
Identity = 42/114 (36.84%), Postives = 68/114 (59.65%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + +G IHF L Y+ Q  TL + I QGK+L  KD  GTSDPY  +   P  +     +T++K +TLNP WN  F F  F  ++L    +H+ ++D+D++   +++GEV+  L ++
Sbjct:   42 ENVGQIHFSLEYDFQNTTLILKILQGKDLPAKDLSGTSDPYVRVTLLPDKKHR--LETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQV 153

[Close]

BLAST of Synaptotagmin VIa vs. TrEMBL
Match: N6T9P1 (C2 domain-containing protein (Fragment) OS=Dendroctonus ponderosae OX=77166 GN=D910_01214 PE=4 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 5.262e-15
Identity = 42/114 (36.84%), Postives = 68/114 (59.65%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            + +G IHF L Y+ Q  TL + I QGK+L  KD  GTSDPY  +   P  +     +T++K +TLNP WN  F F  F  ++L    +H+ ++D+D++   +++GEV+  L ++
Sbjct:   46 ENVGQIHFSLEYDFQNTTLILKILQGKDLPAKDLSGTSDPYVRVTLLPDKKHRL--ETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQV 157

[Close]

BLAST of Synaptotagmin VIa vs. TrEMBL
Match: A0A1A9Z228 (C2 domain-containing protein OS=Glossina pallidipes OX=7398 PE=4 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 6.455e-15
Identity = 44/125 (35.20%), Postives = 70/125 (56.00%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKK-------LHGKD 617
            + +G IHF L Y+ Q  +L + + QGK L  KD  GTSDPY  +   P  +     +T++K +TLNP WN  F F  F  ++L    +H+ ++D+D++   +++GEV+  L +       LHG D
Sbjct:   68 ENVGQIHFSLEYDFQNTSLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHRL--ETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQQHRVSTYLHGHD 190

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BLAST of Synaptotagmin VIa vs. Ensembl Cavefish
Match: syt9b (synaptotagmin 9 [Source:NCBI gene;Acc:103033725])

HSP 1 Score: 80.1073 bits (196), Expect = 1.239e-15
Identity = 43/119 (36.13%), Postives = 70/119 (58.82%), Query Frame = 3

Query:  237 GRNIDPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
            GR  D       G +HF+L+Y+   + L V I + ++L  KD  GTSDPY  I   P  +    ++T+V  KTLNPV++ VF+ F   + EL+  ++H ++YD+D++  H+ +G+V  D
Sbjct:  221 GRRAD-----SCGRLHFILKYDCDLEQLIVKIHKAEDLPAKDFSGTSDPYVKIYLLPERKTK--HQTKVHRKTLNPVFDEVFL-FPVAYAELNMRKLHFSVYDFDRFSRHDLIGQVVVD 331

HSP 2 Score: 56.9954 bits (136), Expect = 2.475e-8
Identity = 38/118 (32.20%), Postives = 56/118 (47.46%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYY-DLKKLHGKDH 620
            LG + F L Y      L + I + +NL   D  G SDPY  +      R     KT  K  TLNPV+N   V F+   E +D+  + I + D+D+ G +E +G     +  +  G+DH
Sbjct:  359 LGDLMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIV-FDVPPENIDQISLLIAVMDYDRVGHNEIIGVCRVGNTAESLGRDH 475

HSP 3 Score: 53.5286 bits (127), Expect = 3.519e-7
Identity = 45/158 (28.48%), Postives = 75/158 (47.47%), Query Frame = 3

Query:  939 RRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM--IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWH 1406
            R  ++ K++  +       G+++ SL Y+     L + IIKARN+  +D T  A  PY  +  +  G   +K K    TS +  T  PV+NE     VPP+ + Q ++ I V     +    ++ +G+ R+G       + H+ E L    KPI +WH
Sbjct:  341 RETKLCKDILYVTADNVDLGDLMFSLCYLPTAGRLTITIIKARNLKAMDITG-ASDPYVKVSLMCDGRRLKKRK----TSTKRNTLNPVYNEAIVFDVPPENIDQISLLIAVM--DYDRVGHNEIIGVCRVGNTAESLGRDHWNEMLTYPRKPIAHWH 491

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BLAST of Synaptotagmin VIa vs. Ensembl Cavefish
Match: syt6a (synaptotagmin-6-like [Source:NCBI gene;Acc:103041393])

HSP 1 Score: 79.337 bits (194), Expect = 2.256e-15
Identity = 42/110 (38.18%), Postives = 67/110 (60.91%), Query Frame = 3

Query:  255 GIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            G  +  G I+F LRY+ + +TL VNI +  +L  KD  G+SDPY  I   P   D   ++T V  KTLNP +N  F  F  +++EL   ++H++++D+D++  H+ +GEV
Sbjct:  240 GGGKNCGKINFSLRYDYENETLLVNILKAFDLPAKDLCGSSDPYVKIYLLP---DRKKFQTRVHRKTLNPTFNESFQ-FPVSYDELPARKLHLSVFDFDRFSRHDMIGEV 345

HSP 2 Score: 51.2174 bits (121), Expect = 1.702e-6
Identity = 48/153 (31.37%), Postives = 70/153 (45.75%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALG--EVYYDLKKLHGKDHEEKE---EDQPNEYAESLNVEKLSIKEWVETTNS 713
            LG I F L Y      L + + + +NL   D  G SDPY  +      R     KT +K  TLNP +N   +F +   E +D+  +HI++ D+D  G +E +G   V    + L G+DH  +      +P  +   L   K S KEW   T S
Sbjct:  376 LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLICDGRRLKKKKTTIKKNTLNPTYNEAIIF-DIPPESMDQVSLHISVMDYDLVGHNEIIGVNRVGCGAEGL-GRDHWNEMLAYPRKPIAHWHPLLESKKSEKEWKTRTAS 526

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BLAST of Synaptotagmin VIa vs. Ensembl Cavefish
Match: syt6a (synaptotagmin-6-like [Source:NCBI gene;Acc:103041393])

HSP 1 Score: 78.5666 bits (192), Expect = 2.474e-15
Identity = 42/110 (38.18%), Postives = 67/110 (60.91%), Query Frame = 3

Query:  255 GIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            G  +  G I+F LRY+ + +TL VNI +  +L  KD  G+SDPY  I   P   D   ++T V  KTLNP +N  F  F  +++EL   ++H++++D+D++  H+ +GEV
Sbjct:  153 GGGKNCGKINFSLRYDYENETLLVNILKAFDLPAKDLCGSSDPYVKIYLLP---DRKKFQTRVHRKTLNPTFNESFQ-FPVSYDELPARKLHLSVFDFDRFSRHDMIGEV 258

HSP 2 Score: 50.447 bits (119), Expect = 2.765e-6
Identity = 34/103 (33.01%), Postives = 51/103 (49.51%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALG 578
            LG I F L Y      L + + + +NL   D  G SDPY  +      R     KT +K  TLNP +N   +F +   E +D+  +HI++ D+D  G +E +G
Sbjct:  289 LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLICDGRRLKKKKTTIKKNTLNPTYNEAIIF-DIPPESMDQVSLHISVMDYDLVGHNEIIG 390

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BLAST of Synaptotagmin VIa vs. Ensembl Cavefish
Match: syt7a (synaptotagmin VIIa [Source:ZFIN;Acc:ZDB-GENE-090601-5])

HSP 1 Score: 78.9518 bits (193), Expect = 3.102e-15
Identity = 42/116 (36.21%), Postives = 66/116 (56.90%), Query Frame = 3

Query:  258 IDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            I + LG I F + Y  Q  TL V I +G++L  KD  GTSDP+  I   P  +     +T+VK K LNP WN  F+F  F +E++    +++ + D+D++  ++ +GEV   L K+
Sbjct:  302 ISEKLGRIQFSVGYSFQDSTLTVKIMKGQDLPAKDFSGTSDPFVKIYLLPDKKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVRERTLYLQVLDYDRFSRNDPIGEVSIPLNKV 415

HSP 2 Score: 58.151 bits (139), Expect = 1.163e-8
Identity = 46/157 (29.30%), Postives = 74/157 (47.13%), Query Frame = 3

Query:  957 KNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM----IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIR 1415
            K L+   +   + G++L+SL Y     T+ V IIK RN+    I  T    V   ++ H     +++KT +I R         PV+NE FP  VP   L++T + I V      S  ++D +G I L  K+ PA+  H+ + L      +  WH ++
Sbjct:  425 KELKPCSDGSGSRGDLLLSLCYNPTANTITVNIIKGRNLKAMDIGGTSDPYVKVWLM-HKDKRVEKKKTVTIKRCL------NPVFNESFPFDVPAHVLRETTIIITVMDKDRLS--RNDVIGKIYLSWKSGPAEVKHWKDMLSRPRTNVAQWHALK 572

HSP 3 Score: 51.2174 bits (121), Expect = 2.012e-6
Identity = 36/109 (33.03%), Postives = 52/109 (47.71%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLK 599
            G +   L Y     T+ VNI +G+NL   D  GTSDPY  +    + +     KT    + LNPV+N  F F    H  L    I IT+ D D+   ++ +G++Y   K
Sbjct:  438 GDLLLSLCYNPTANTITVNIIKGRNLKAMDIGGTSDPYVKVWLMHKDKRVEKKKTVTIKRCLNPVFNESFPFDVPAH-VLRETTIIITVMDKDRLSRNDVIGKIYLSWK 545

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BLAST of Synaptotagmin VIa vs. Ensembl Cavefish
Match: syt9a (synaptotagmin IXa [Source:ZFIN;Acc:ZDB-GENE-031002-18])

HSP 1 Score: 77.0258 bits (188), Expect = 3.234e-15
Identity = 40/105 (38.10%), Postives = 65/105 (61.90%), Query Frame = 3

Query:  279 IHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
            +HF+L+Y+   + L V I + ++L  KD  GTSDPY  I   P  +    ++T+V  KTLNPV++ VF+ F   + EL   ++H T+YD+D++  H+ +G+V  D
Sbjct:  179 LHFILKYDCDLEQLIVKIHRAQDLPAKDFSGTSDPYVKIYLLPDRKTK--HQTKVHRKTLNPVFDEVFL-FPVAYAELPTRKLHFTVYDFDRFSRHDIIGQVVVD 280

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BLAST of Synaptotagmin VIa vs. Ensembl Sea Lamprey
Match: SYT6 (synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638])

HSP 1 Score: 75.485 bits (184), Expect = 9.426e-16
Identity = 42/108 (38.89%), Postives = 62/108 (57.41%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDP-RFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
            G ++F L Y+ + + L V + +   L  KD  GTSDPY  I   P R R    Y+T+V  KTLNPV+   F FF   + EL   R+H ++YD+D++  H+ +G+V  D
Sbjct:  114 GKLNFALHYDYEMEQLLVRVCRAAELPAKDFSGTSDPYVKIYLLPDRKRK---YQTKVHRKTLNPVFEETFQFF-VPYAELPARRLHFSVYDFDRFSRHDTIGQVVVD 217

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BLAST of Synaptotagmin VIa vs. Ensembl Sea Lamprey
Match: SYT6 (synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638])

HSP 1 Score: 75.485 bits (184), Expect = 2.364e-15
Identity = 44/120 (36.67%), Postives = 66/120 (55.00%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEEK 629
             G I+F +RY+ + + L V I +  +L  KD  GTSDPY  I   P  +    Y+T+V  KTLNPV++  F  F   + EL   R+H ++YD+D++  H+ +G V  D   L   DH  +
Sbjct:  184 CGRINFQVRYDYEGEQLVVKINKAVDLPAKDFSGTSDPYVKIYLLPERKRK--YQTKVHRKTLNPVFDETFQ-FGVPYSELASRRLHFSVYDFDRFSRHDIIGTVLVD-NLLEATDHSRE 299

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BLAST of Synaptotagmin VIa vs. Ensembl Sea Lamprey
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315])

HSP 1 Score: 69.3218 bits (168), Expect = 7.285e-14
Identity = 39/105 (37.14%), Postives = 57/105 (54.29%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            LG + F + Y+ Q   L V + Q   L   D  GTSDPY  +   P  +    Y+T+V  KTLNPV+N  FV F   + EL    + + +YD+D++  H+ +GEV
Sbjct:   80 LGKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPDKKKK--YETKVHRKTLNPVFNESFV-FKVPYSELGGKTLVMAVYDFDRFSKHDIIGEV 181

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Sea Lamprey
Match: syt2a (synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503-315])

HSP 1 Score: 69.707 bits (169), Expect = 8.301e-14
Identity = 39/105 (37.14%), Postives = 57/105 (54.29%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            LG + F + Y+ Q   L V + Q   L   D  GTSDPY  +   P  +    Y+T+V  KTLNPV+N  FV F   + EL    + + +YD+D++  H+ +GEV
Sbjct:   97 LGKLQFSIDYDFQNNQLTVGVIQAAELPALDMGGTSDPYVKLFLMPDKKKK--YETKVHRKTLNPVFNESFV-FKVPYSELGGKTLVMAVYDFDRFSKHDIIGEV 198

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Sea Lamprey
Match: SYT5 (synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513])

HSP 1 Score: 66.6254 bits (161), Expect = 6.326e-13
Identity = 39/120 (32.50%), Postives = 60/120 (50.00%), Query Frame = 3

Query:  243 NIDPGI------DQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            +IDPG       +  LG + F L Y ++T    V I Q  +L   D  G SDPY  +   P  +    ++T V  KTLNP++   F F     EEL    + + +YD+D++  H+ +GE+
Sbjct:   64 DIDPGFIEDIYKENTLGRLQFSLDYNLKTSQFTVGILQATDLAAMDIGGMSDPYVRVYLLPHKKKK--FETSVHRKTLNPIFEEKFTF-TVPFEELVERVLVMVVYDFDRFSRHDIIGEL 180

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BLAST of Synaptotagmin VIa vs. Ensembl Yeast
Match: TCB3 (Cortical ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to the plasma membrane (PM) and regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1p phosphatase to its substrate PI4P in the PM; localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact [Source:SGD;Acc:S000004537])

HSP 1 Score: 50.447 bits (119), Expect = 5.358e-7
Identity = 29/99 (29.29%), Postives = 49/99 (49.49%), Query Frame = 3

Query:  309 TKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            T  L + +  G  L   D  G SDP+  I  +    D  ++K+ +K KTL+PVWN        +     ++++   + DWD+ GD++ LG+   D+  L
Sbjct: 1133 TGYLNIKLISGHGLKSADRNGYSDPFVHIFVN----DKKVFKSNIKKKTLDPVWNEDAKIPILSRS---KNQVIFNVLDWDRAGDNDDLGQASLDVSSL 1224

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BLAST of Synaptotagmin VIa vs. Ensembl Nematostella
Match: EDO31746 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX17])

HSP 1 Score: 73.1738 bits (178), Expect = 4.014e-14
Identity = 39/105 (37.14%), Postives = 60/105 (57.14%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            +G I+F L Y     TL V I + +++  KD  G+SDPY  I   P  +    Y+T+V  KTLNPV+N  FVF N  + E+    + + L+D+D++  H+ +GE 
Sbjct:   84 IGRINFTLDYSFTDNTLTVGIIRAEDIPAKDFSGSSDPYVKIMLLPDKKKK--YETKVHRKTLNPVFNEQFVFKNIPYSEITNRILLMELFDFDRFSRHDLIGEA 186

HSP 2 Score: 54.6842 bits (130), Expect = 4.107e-8
Identity = 37/105 (35.24%), Postives = 55/105 (52.38%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            LG I F LRY   +  L++ I + K+L   D  G SDPY  I      R     KT VK +TLNP +N  F  F    E++++  + I++ D+D+ G  E +G+ 
Sbjct:  221 LGDICFSLRYVPSSGKLQITIVEAKSLKSMDLTGYSDPYVKIALVQEGRKIKKKKTTVKKRTLNPYYNETFT-FTVAFEKIEQTSLIISVLDYDRVGKSEMIGKC 324

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BLAST of Synaptotagmin VIa vs. Ensembl Nematostella
Match: EDO41933 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S352])

HSP 1 Score: 71.2478 bits (173), Expect = 8.937e-14
Identity = 39/113 (34.51%), Postives = 57/113 (50.44%), Query Frame = 3

Query:  267 GLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            GLGL+ F LRY+     L V +   K L   D  GTSDPY  +   P        ++  K KTLNPV+N    ++  T EE+    + + ++D D  G ++ +GE   +LK L
Sbjct:   18 GLGLLEFTLRYQKLDSRLDVVLHDAKGLKPMDHGGTSDPYVKLHLLPGASKSNKLRSHTKYKTLNPVFNETLTYYGITEEEISSKTLRLQVFDEDTIGRNDFIGETSINLKLL 130

HSP 2 Score: 59.6918 bits (143), Expect = 6.497e-10
Identity = 33/109 (30.28%), Postives = 54/109 (49.54%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDL 596
            LG I   L+Y  Q   L V + +   L   D  G SDPY      P  +     +T ++ KTLNP +N  FV ++  H EL +  + +T++D+D    ++ +G V  ++
Sbjct:  154 LGRIQLALKYNTQRGMLFVTVMRCSGLASMDANGYSDPYVKCYLKPDPQKKSKRRTNIRKKTLNPEFNEEFV-YDIAHHELAKKSLEVTVWDYDVGKSNDFIGGVILNI 261

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BLAST of Synaptotagmin VIa vs. Ensembl Nematostella
Match: EDO43704 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXY7])

HSP 1 Score: 69.707 bits (169), Expect = 2.361e-13
Identity = 38/105 (36.19%), Postives = 56/105 (53.33%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEV 584
            LG I F L Y      L + + + + L  KD  GTSDP+  I   P  +     +T VK K LNPVWN VF F  F H +L    +++ + D+D++  ++ +GEV
Sbjct:    3 LGKIFFSLTYYSSDSVLTLKVLKAQGLPAKDFSGTSDPFVKIMLLPDKKHK--LETRVKRKNLNPVWNEVFTFEGFPHNKLMGKTLYMQVLDYDRFSRNDPIGEV 105

HSP 2 Score: 55.0694 bits (131), Expect = 1.754e-8
Identity = 46/157 (29.30%), Postives = 73/157 (46.50%), Query Frame = 3

Query:  945 IEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM--IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDEL-GLIRLGLKTYPAQKAHYIEFLGNIGKPIENWH 1406
            +   K+L      R   G++LVSL Y   N  + V ++KA  +  +D T  +  PY  ++   +  DR   K   +T+ +  T  PVWNE F   VP  K++       VF+     +   +EL G + LG +T  +   H+ E + N  KP+  WH
Sbjct:  119 LTFTKDLLPCKKDRVPLGDLLVSLMYQPTNNRIIVVVMKANKLKAMDLTGSS-DPY--VKMYIMHKDRRLDKK--KTTIKRRTRDPVWNESFIFDVPLDKIRDLTF---VFNVMDYDRITQNELIGQVILGYRTTGSSLRHWTEMMNNPRKPVAQWH 267

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Nematostella
Match: EDO32931 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STM9])

HSP 1 Score: 69.3218 bits (168), Expect = 1.714e-12
Identity = 41/110 (37.27%), Postives = 63/110 (57.27%), Query Frame = 3

Query:  291 LRYEVQTKTLKVNIFQGKNLVGKD----PRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVF-VFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            L+Y +    L++ + + K+LV KD     +GTSDPYA++K   +      ++TE K +TLNP WN VF VF + +  +    +I I L+D D+  D EALG V  D+  +
Sbjct:  309 LKYPLPDGVLRIEVTEAKDLVAKDIAVFKKGTSDPYAMVKVGAQ-----TFRTETKKETLNPKWNEVFEVFVDNSQGQ----KIKIQLFDEDRASDDEALGSVEADISTV 409

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BLAST of Synaptotagmin VIa vs. Ensembl Nematostella
Match: EDO49802 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFY4])

HSP 1 Score: 67.3958 bits (163), Expect = 2.860e-12
Identity = 38/112 (33.93%), Postives = 62/112 (55.36%), Query Frame = 3

Query:  273 GLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLH 608
            G I   L+Y  + + L V + + ++LV +D  G SDPY V++  P   ++   KT  K KTLNPV+N +F  F   H  L   ++  T++D D +G+ +  GE   DL +++
Sbjct:   31 GDIEMSLKYNHREQLLLVKVIRARDLVPRDLNGKSDPYVVLELVPDRLEEGTKKTRFKQKTLNPVFNEIFQ-FKVPHNNLTDTKLCATIWDHDFFGEDDFNGEAVVDLSRVN 141

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BLAST of Synaptotagmin VIa vs. Ensembl Medaka
Match: ENSORLT00000000569.2 (pep primary_assembly:ASM223467v1:12:1368783:1372867:-1 gene:ENSORLG00000000462.2 transcript:ENSORLT00000000569.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 76.6406 bits (187), Expect = 1.551e-15
Identity = 39/113 (34.51%), Postives = 56/113 (49.56%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLH 608
            LG + F L YE +   L   I + K L   D  G +DPY  +   P        +T+    TLNP WN   V+   T E++ R  + +++ D DK+G +E +GE    LKKLH
Sbjct:   45 LGSLEFSLLYEQEGHALHCCIIKAKGLKPMDSNGLADPYVKLHLLPGASKSTKLRTKTLKNTLNPAWNETLVYHGITDEDMARKTLRLSVSDEDKFGHNEFIGETRVALKKLH 157

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Medaka
Match: syt7a (synaptotagmin-7-like [Source:NCBI gene;Acc:101169108])

HSP 1 Score: 78.1814 bits (191), Expect = 2.711e-15
Identity = 41/116 (35.34%), Postives = 66/116 (56.90%), Query Frame = 3

Query:  258 IDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            I + LG I F + Y  Q  TL V + +G++L  KD  GTSDP+  I   P  +     +T+VK K LNP WN  F+F  F +E++    +++ + D+D++  ++ +GEV   L K+
Sbjct:  121 ISEKLGRIQFSIGYSFQNTTLTVKVLKGQDLPAKDFSGTSDPFVKIYLLPDKKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVRERTLYLQVLDYDRFSRNDPIGEVSIPLNKV 234

HSP 2 Score: 59.6918 bits (143), Expect = 3.079e-9
Identity = 48/157 (30.57%), Postives = 71/157 (45.22%), Query Frame = 3

Query:  957 KNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM----IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIR 1415
            K L+   +     GE+LVSL Y     T+ V IIKARN+    I  T     PY  +  +      EK K++           PV+NE FP  VP   L++T + I V      S  ++D +G I L  K+ PA+  H+ + L      +  WH ++
Sbjct:  244 KELKPCSDGSGRRGELLVSLCYNPTANTITVNIIKARNLKAMDIGGTSD---PYVKVWLMHKDKRVEKKKTVVIKCCL----NPVFNESFPFDVPAHVLRETTIVITVMDKDRLS--RNDVIGKIYLSWKSGPAEVKHWKDMLARPRTNVAQWHALK 391

HSP 3 Score: 48.9062 bits (115), Expect = 7.431e-6
Identity = 35/103 (33.98%), Postives = 49/103 (47.57%), Query Frame = 3

Query:  291 LRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLK 599
            L Y     T+ VNI + +NL   D  GTSDPY  +    + +     KT V    LNPV+N  F F    H  L    I IT+ D D+   ++ +G++Y   K
Sbjct:  263 LCYNPTANTITVNIIKARNLKAMDIGGTSDPYVKVWLMHKDKRVEKKKTVVIKCCLNPVFNESFPFDVPAH-VLRETTIVITVMDKDRLSRNDVIGKIYLSWK 364

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Medaka
Match: syt9b (synaptotagmin-9 [Source:NCBI gene;Acc:101171486])

HSP 1 Score: 78.9518 bits (193), Expect = 2.885e-15
Identity = 42/119 (35.29%), Postives = 70/119 (58.82%), Query Frame = 3

Query:  237 GRNIDPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
            GR  D       G +HF+L++++  + L V I + ++L  KD  GTSDPY  I   P  +    ++T+V  KTLNPV++ VF+ F   + EL   ++H ++YD+D++  H+ +G+V  D
Sbjct:  228 GRRTD-----SCGRLHFILKFDLDLEQLIVKIHRAQDLPAKDFSGTSDPYVKIYLLPDRKTK--HQTKVHRKTLNPVFDEVFL-FPVAYAELSSRKLHFSVYDFDRFSRHDLIGQVVVD 338

HSP 2 Score: 58.151 bits (139), Expect = 1.158e-8
Identity = 45/158 (28.48%), Postives = 78/158 (49.37%), Query Frame = 3

Query:  939 RRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM--IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWH 1406
            R  ++ +++Q + +     GE++ SL Y+     L + +IKARN+  +D T  A  PY  +  +  G   +K K    TS +  T  PV+NE     VPP+ + Q ++ I V     +    ++ +G+ R+G +     + H+ E L    KPI +WH
Sbjct:  348 RETKLCRDIQYVTSDNVDLGELMFSLCYLPTAGRLTITMIKARNLKAMDITG-ASDPYVKVSLMCEGRRLKKRK----TSTKRNTLNPVYNEAIVFDVPPENIDQISLLIAVMD--YDRVGHNEVIGVCRVGSEAESLGRDHWNEMLSYPRKPIAHWH 498

HSP 3 Score: 57.7658 bits (138), Expect = 1.344e-8
Identity = 39/119 (32.77%), Postives = 58/119 (48.74%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALG--EVYYDLKKLHGKDH 620
            LG + F L Y      L + + + +NL   D  G SDPY  +      R     KT  K  TLNPV+N   V F+   E +D+  + I + D+D+ G +E +G   V  + + L G+DH
Sbjct:  366 LGELMFSLCYLPTAGRLTITMIKARNLKAMDITGASDPYVKVSLMCEGRRLKKRKTSTKRNTLNPVYNEAIV-FDVPPENIDQISLLIAVMDYDRVGHNEVIGVCRVGSEAESL-GRDH 482

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Medaka
Match: syt7a (synaptotagmin-7-like [Source:NCBI gene;Acc:101169108])

HSP 1 Score: 79.337 bits (194), Expect = 2.922e-15
Identity = 41/116 (35.34%), Postives = 66/116 (56.90%), Query Frame = 3

Query:  258 IDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKL 605
            I + LG I F + Y  Q  TL V + +G++L  KD  GTSDP+  I   P  +     +T+VK K LNP WN  F+F  F +E++    +++ + D+D++  ++ +GEV   L K+
Sbjct:  471 ISEKLGRIQFSIGYSFQNTTLTVKVLKGQDLPAKDFSGTSDPFVKIYLLPDKKHK--LETKVKRKNLNPHWNETFLFEGFPYEKVRERTLYLQVLDYDRFSRNDPIGEVSIPLNKV 584

HSP 2 Score: 56.9954 bits (136), Expect = 2.800e-8
Identity = 48/157 (30.57%), Postives = 71/157 (45.22%), Query Frame = 3

Query:  957 KNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM----IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIR 1415
            K L+   +     GE+LVSL Y     T+ V IIKARN+    I  T     PY  +  +      EK K++           PV+NE FP  VP   L++T + I V      S  ++D +G I L  K+ PA+  H+ + L      +  WH ++
Sbjct:  594 KELKPCSDGSGRRGELLVSLCYNPTANTITVNIIKARNLKAMDIGGTSD---PYVKVWLMHKDKRVEKKKTVVIKCCL----NPVFNESFPFDVPAHVLRETTIVITVMDKDRLS--RNDVIGKIYLSWKSGPAEVKHWKDMLARPRTNVAQWHALK 741

HSP 3 Score: 48.9062 bits (115), Expect = 9.407e-6
Identity = 34/103 (33.01%), Postives = 49/103 (47.57%), Query Frame = 3

Query:  291 LRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLK 599
            L Y     T+ VNI + +NL   D  GTSDPY  +    + +     KT V    LNPV+N  F  F+     L    I IT+ D D+   ++ +G++Y   K
Sbjct:  613 LCYNPTANTITVNIIKARNLKAMDIGGTSDPYVKVWLMHKDKRVEKKKTVVIKCCLNPVFNESFP-FDVPAHVLRETTIVITVMDKDRLSRNDVIGKIYLSWK 714

[Close]

BLAST of Synaptotagmin VIa vs. Ensembl Medaka
Match: syt9b (synaptotagmin-9 [Source:NCBI gene;Acc:101171486])

HSP 1 Score: 78.5666 bits (192), Expect = 3.318e-15
Identity = 42/119 (35.29%), Postives = 70/119 (58.82%), Query Frame = 3

Query:  237 GRNIDPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYD 593
            GR  D       G +HF+L++++  + L V I + ++L  KD  GTSDPY  I   P  +    ++T+V  KTLNPV++ VF+ F   + EL   ++H ++YD+D++  H+ +G+V  D
Sbjct:  228 GRRTD-----SCGRLHFILKFDLDLEQLIVKIHRAQDLPAKDFSGTSDPYVKIYLLPDRKTK--HQTKVHRKTLNPVFDEVFL-FPVAYAELSSRKLHFSVYDFDRFSRHDLIGQVVVD 338

HSP 2 Score: 58.151 bits (139), Expect = 1.124e-8
Identity = 39/119 (32.77%), Postives = 58/119 (48.74%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALG--EVYYDLKKLHGKDH 620
            LG + F L Y      L + + + +NL   D  G SDPY  +      R     KT  K  TLNPV+N   V F+   E +D+  + I + D+D+ G +E +G   V  + + L G+DH
Sbjct:  366 LGELMFSLCYLPTAGRLTITMIKARNLKAMDITGASDPYVKVSLMCEGRRLKKRKTSTKRNTLNPVYNEAIV-FDVPPENIDQISLLIAVMDYDRVGHNEVIGVCRVGSEAESL-GRDH 482

HSP 3 Score: 57.7658 bits (138), Expect = 1.410e-8
Identity = 45/158 (28.48%), Postives = 78/158 (49.37%), Query Frame = 3

Query:  939 RRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNM--IDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWH 1406
            R  ++ +++Q + +     GE++ SL Y+     L + +IKARN+  +D T  A  PY  +  +  G   +K K    TS +  T  PV+NE     VPP+ + Q ++ I V     +    ++ +G+ R+G +     + H+ E L    KPI +WH
Sbjct:  348 RETKLCRDIQYVTSDNVDLGELMFSLCYLPTAGRLTITMIKARNLKAMDITG-ASDPYVKVSLMCEGRRLKKRK----TSTKRNTLNPVYNEAIVFDVPPENIDQISLLIAVMD--YDRVGHNEVIGVCRVGSEAESLGRDHWNEMLSYPRKPIAHWH 498

[Close]

BLAST of Synaptotagmin VIa vs. Planmine SMEST
Match: SMESG000043595.1 (SMESG000043595.1)

HSP 1 Score: 760.755 bits (1963), Expect = 0.000e+0
Identity = 415/415 (100.00%), Postives = 415/415 (100.00%), Query Frame = 3

Query:  174 KKTKLXXXXXXXXXXXXXXIIGRNIDPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEEKEEDQPNEYAESLNVEKLSIKEWVETTNSKYGIEEPPKELEPITEEDEKAVQKSASMIFNXXXXXXXXXXXXXXXXXXXXXXXPDAEGNMNGDDEENIPTVNVIRRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNMIDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIRK 1418
            KKTKLEDEFEEPEPERPLPIIGRNIDPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEEKEEDQPNEYAESLNVEKLSIKEWVETTNSKYGIEEPPKELEPITEEDEKAVQKSASMIFNEHYDEYEEMEEEDEEELEYQNDEPDAEGNMNGDDEENIPTVNVIRRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNMIDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIRK
Sbjct:   35 KKTKLEDEFEEPEPERPLPIIGRNIDPGIDQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEEKEEDQPNEYAESLNVEKLSIKEWVETTNSKYGIEEPPKELEPITEEDEKAVQKSASMIFNEHYDEYEEMEEEDEEELEYQNDEPDAEGNMNGDDEENIPTVNVIRRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLNVKIIKARNMIDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTPVWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPAQKAHYIEFLGNIGKPIENWHLIRK 449

HSP 2 Score: 65.0846 bits (157), Expect = 4.264e-11
Identity = 32/33 (96.97%), Postives = 32/33 (96.97%), Query Frame = 1

Query:   82 EEITIIDVIKDLRKLWPLSVIFPEAVKETHEKK 180
             EITIIDVIKDLRKLWPLSVIFPEAVKETHEKK
Sbjct:    4 NEITIIDVIKDLRKLWPLSVIFPEAVKETHEKK 36

[Close]

BLAST of Synaptotagmin VIa vs. Planmine SMEST
Match: SMESG000040037.1 (SMESG000040037.1)

HSP 1 Score: 69.707 bits (169), Expect = 1.397e-12
Identity = 42/132 (31.82%), Postives = 69/132 (52.27%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPR-GTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLH---GKDHEEKEEDQPNEY 653
            LG + F   Y+ Q + L V+I +  +L  KD + GTSDPY  ++  P  R     KT+++ KTLNPV+   F F +FT  ++    +H  +  +D++   + +GEV   L +L    G +    +E QP  +
Sbjct:  134 LGSLEFSASYDNQKQILSVSILRCCDLPSKDTQLGTSDPYVKLQLLPEKRQR--VKTQIQRKTLNPVFGETFTFNSFTLNQVKSTSLHFVVLSFDRFSRDDIIGEVVCPLMELDLNLGSEVVLTKEIQPRRF 263

HSP 2 Score: 50.447 bits (119), Expect = 1.892e-6
Identity = 42/146 (28.77%), Postives = 64/146 (43.84%), Query Frame = 3

Query:  261 DQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRG-TSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEEKEEDQPNEYAESLNVEKLSIKEW 695
            D   G I   + ++   K L V I + +NL   D  G   DPY  +      +     KT VK +TLNPV+N  F F    +E L    I + + D+D+   +E +G +      + G    EKEE     + E +N  +  + EW
Sbjct:  267 DDDRGEILLSICHQPAAKMLTVVILKARNLPKTDATGLAGDPYVKLYLVQNGQRLAKKKTHVKKRTLNPVYNQSFSFDLQDNENLLNIAIELLIMDYDRVTKNEVIGRL------MIGYGFGEKEE---QHWTEVINNPRKQMAEW 403

[Close]

BLAST of Synaptotagmin VIa vs. Planmine SMEST
Match: SMESG000040037.1 (SMESG000040037.1)

HSP 1 Score: 69.3218 bits (168), Expect = 1.563e-12
Identity = 42/132 (31.82%), Postives = 69/132 (52.27%), Query Frame = 3

Query:  270 LGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPR-GTSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLH---GKDHEEKEEDQPNEY 653
            LG + F   Y+ Q + L V+I +  +L  KD + GTSDPY  ++  P  R     KT+++ KTLNPV+   F F +FT  ++    +H  +  +D++   + +GEV   L +L    G +    +E QP  +
Sbjct:  121 LGSLEFSASYDNQKQILSVSILRCCDLPSKDTQLGTSDPYVKLQLLPEKRQR--VKTQIQRKTLNPVFGETFTFNSFTLNQVKSTSLHFVVLSFDRFSRDDIIGEVVCPLMELDLNLGSEVVLTKEIQPRRF 250

HSP 2 Score: 50.0618 bits (118), Expect = 2.273e-6
Identity = 42/146 (28.77%), Postives = 64/146 (43.84%), Query Frame = 3

Query:  261 DQGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRG-TSDPYAVIKFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEEKEEDQPNEYAESLNVEKLSIKEW 695
            D   G I   + ++   K L V I + +NL   D  G   DPY  +      +     KT VK +TLNPV+N  F F    +E L    I + + D+D+   +E +G +      + G    EKEE     + E +N  +  + EW
Sbjct:  254 DDDRGEILLSICHQPAAKMLTVVILKARNLPKTDATGLAGDPYVKLYLVQNGQRLAKKKTHVKKRTLNPVYNQSFSFDLQDNENLLNIAIELLIMDYDRVTKNEVIGRL------MIGYGFGEKEE---QHWTEVINNPRKQMAEW 390

[Close]

BLAST of Synaptotagmin VIa vs. Planmine SMEST
Match: SMESG000059797.1 (SMESG000059797.1)

HSP 1 Score: 65.855 bits (159), Expect = 1.712e-11
Identity = 42/132 (31.82%), Postives = 72/132 (54.55%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVI--KFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEE--KEEDQPN 647
            + LG + + ++Y  ++++L+V +  G +L+  +  GTSDPY  +  K  P+ +    ++T+VK +T NPV+N  F  F  + EEL    +    YD+D++  HE +G +  DL  L      E   E DQP+
Sbjct:   62 ESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLK----FETKVKRRTRNPVFNEDFT-FTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPS 188

[Close]

BLAST of Synaptotagmin VIa vs. Planmine SMEST
Match: SMESG000059797.1 (SMESG000059797.1)

HSP 1 Score: 65.855 bits (159), Expect = 1.838e-11
Identity = 42/132 (31.82%), Postives = 72/132 (54.55%), Query Frame = 3

Query:  264 QGLGLIHFLLRYEVQTKTLKVNIFQGKNLVGKDPRGTSDPYAVI--KFDPRFRDDWLYKTEVKMKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDLKKLHGKDHEE--KEEDQPN 647
            + LG + + ++Y  ++++L+V +  G +L+  +  GTSDPY  +  K  P+ +    ++T+VK +T NPV+N  F  F  + EEL    +    YD+D++  HE +G +  DL  L      E   E DQP+
Sbjct:   59 ESLGKLVYAIKYFPESESLRVTVKSGHDLIKLNTGGTSDPYVKVWLKEKPKLK----FETKVKRRTRNPVFNEDFT-FTVSPEELPTQTLIFFFYDFDRFSKHEQIGCLMLDLGALDLSKLIEDWAELDQPS 185

The following BLAST results are available for this feature:

BLAST of Synaptotagmin VIa vs. Ensembl Human
BLAST of Synaptotagmin VIa vs. Ensembl Celegans
BLAST of Synaptotagmin VIa vs. Ensembl Fly
BLAST of Synaptotagmin VIa vs. Ensembl Zebrafish
BLAST of Synaptotagmin VIa vs. Ensembl Xenopus
BLAST of Synaptotagmin VIa vs. Ensembl Mouse
BLAST of Synaptotagmin VIa vs. UniProt/SwissProt
BLAST of Synaptotagmin VIa vs. TrEMBL
BLAST of Synaptotagmin VIa vs. Ensembl Cavefish
BLAST of Synaptotagmin VIa vs. Ensembl Sea Lamprey
BLAST of Synaptotagmin VIa vs. Ensembl Yeast
BLAST of Synaptotagmin VIa vs. Ensembl Nematostella
BLAST of Synaptotagmin VIa vs. Ensembl Medaka
BLAST of Synaptotagmin VIa vs. Planmine SMEST

BLAST of Synaptotagmin VIa vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SYT9	1.910e-14	35.45	synaptotagmin 9 [Source:HGNC Symbol;Acc:HGNC:19265...	[more]
RPH3A	3.172e-14	33.04	rabphilin 3A [Source:HGNC Symbol;Acc:HGNC:17056]	[more]
RPH3A	3.172e-14	33.04	rabphilin 3A [Source:HGNC Symbol;Acc:HGNC:17056]	[more]
RPH3A	3.172e-14	33.04	rabphilin 3A [Source:HGNC Symbol;Acc:HGNC:17056]	[more]
RPH3A	3.734e-14	33.04	rabphilin 3A [Source:HGNC Symbol;Acc:HGNC:17056]	[more]

BLAST of Synaptotagmin VIa vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
snt-1	3.078e-11	34.82	Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:...	[more]
snt-1	4.072e-11	34.82	Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:...	[more]
snt-3	1.303e-10	31.25	SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5...	[more]
snt-3	1.303e-10	31.25	SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5...	[more]
rbf-1	1.844e-10	32.81	Rabphilin-1 [Source:UniProtKB/Swiss-Prot;Acc:P418...	[more]

BLAST of Synaptotagmin VIa vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Syt7	1.026e-17	35.54	gene:FBgn0039900 transcript:FBtr0305658	[more]
Syt7	1.242e-17	35.54	gene:FBgn0039900 transcript:FBtr0089139	[more]
Syt7	1.389e-17	35.54	gene:FBgn0039900 transcript:FBtr0089134	[more]
Syt7	2.438e-17	35.65	gene:FBgn0039900 transcript:FBtr0343990	[more]
Syt7	2.438e-17	35.65	gene:FBgn0039900 transcript:FBtr0089137	[more]

BLAST of Synaptotagmin VIa vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
syt7a	2.359e-15	36.21	synaptotagmin VIIa [Source:ZFIN;Acc:ZDB-GENE-09060...	[more]
syt7a	4.846e-15	36.21	synaptotagmin VIIa [Source:ZFIN;Acc:ZDB-GENE-09060...	[more]
syt9a	6.648e-15	35.78	synaptotagmin IXa [Source:ZFIN;Acc:ZDB-GENE-031002...	[more]
syt7b	8.492e-15	35.71	synaptotagmin VIIb [Source:ZFIN;Acc:ZDB-GENE-09060...	[more]
syt7b	1.246e-14	34.48	synaptotagmin VIIb [Source:ZFIN;Acc:ZDB-GENE-09060...	[more]

BLAST of Synaptotagmin VIa vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RPH3A	1.090e-14	34.82	rabphilin 3A [Source:NCBI gene;Acc:100487950]	[more]
RPH3A	1.838e-14	34.82	rabphilin 3A [Source:NCBI gene;Acc:100487950]	[more]
wnt6	1.879e-14	35.78	Wnt family member 6 [Source:Xenbase;Acc:XB-GENE-48...	[more]
RPH3A	1.897e-14	34.82	rabphilin 3A [Source:NCBI gene;Acc:100487950]	[more]
RPH3A	2.321e-14	34.82	rabphilin 3A [Source:NCBI gene;Acc:100487950]	[more]

BLAST of Synaptotagmin VIa vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Syt9	4.880e-14	35.45	synaptotagmin IX [Source:MGI Symbol;Acc:MGI:192637...	[more]
Syt7	1.137e-13	34.21	synaptotagmin VII [Source:MGI Symbol;Acc:MGI:18595...	[more]
Syt7	1.146e-13	34.82	synaptotagmin VII [Source:MGI Symbol;Acc:MGI:18595...	[more]
Syt7	1.154e-13	34.21	synaptotagmin VII [Source:MGI Symbol;Acc:MGI:18595...	[more]
Syt7	1.205e-13	34.82	synaptotagmin VII [Source:MGI Symbol;Acc:MGI:18595...	[more]

BLAST of Synaptotagmin VIa vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P24507\|SY63_DIPOM	2.394e-14	37.96	Synaptotagmin-C OS=Diplobatis ommata OX=1870830 GN...	[more]
sp\|Q9Y2J0\|RP3A_HUMAN	1.523e-13	33.04	Rabphilin-3A OS=Homo sapiens OX=9606 GN=RPH3A PE=1...	[more]
sp\|Q86SS6\|SYT9_HUMAN	2.350e-13	35.45	Synaptotagmin-9 OS=Homo sapiens OX=9606 GN=SYT9 PE...	[more]
sp\|Q06846\|RP3A_BOVIN	2.496e-13	33.04	Rabphilin-3A OS=Bos taurus OX=9913 GN=RPH3A PE=1 S...	[more]
sp\|Q9R0N9\|SYT9_MOUSE	3.414e-13	35.45	Synaptotagmin-9 OS=Mus musculus OX=10090 GN=Syt9 P...	[more]

BLAST of Synaptotagmin VIa vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
D7EJD0	1.357e-15	36.84	Synaptotagmin 1-like Protein OS=Tribolium castaneu...	[more]
D3TS75	2.989e-15	35.65	Synaptotagmin OS=Glossina morsitans morsitans OX=3...	[more]
U4UCS3	4.159e-15	36.84	C2 domain-containing protein OS=Dendroctonus ponde...	[more]
N6T9P1	5.262e-15	36.84	C2 domain-containing protein (Fragment) OS=Dendroc...	[more]
A0A1A9Z228	6.455e-15	35.20	C2 domain-containing protein OS=Glossina pallidipe...	[more]

BLAST of Synaptotagmin VIa vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
syt9b	1.239e-15	36.13	synaptotagmin 9 [Source:NCBI gene;Acc:103033725]	[more]
syt6a	2.256e-15	38.18	synaptotagmin-6-like [Source:NCBI gene;Acc:1030413...	[more]
syt6a	2.474e-15	38.18	synaptotagmin-6-like [Source:NCBI gene;Acc:1030413...	[more]
syt7a	3.102e-15	36.21	synaptotagmin VIIa [Source:ZFIN;Acc:ZDB-GENE-09060...	[more]
syt9a	3.234e-15	38.10	synaptotagmin IXa [Source:ZFIN;Acc:ZDB-GENE-031002...	[more]

BLAST of Synaptotagmin VIa vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SYT6	9.426e-16	38.89	synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638...	[more]
SYT6	2.364e-15	36.67	synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638...	[more]
syt2a	7.285e-14	37.14	synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
syt2a	8.301e-14	37.14	synaptotagmin IIa [Source:ZFIN;Acc:ZDB-GENE-060503...	[more]
SYT5	6.326e-13	32.50	synaptotagmin 5 [Source:HGNC Symbol;Acc:HGNC:11513...	[more]

BLAST of Synaptotagmin VIa vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
TCB3	5.358e-7	29.29	Cortical ER protein involved in ER-plasma membrane...	[more]

BLAST of Synaptotagmin VIa vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO31746	4.014e-14	37.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41933	8.937e-14	34.51	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43704	2.361e-13	36.19	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32931	1.714e-12	37.27	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49802	2.860e-12	33.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Synaptotagmin VIa vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000000569.2	1.551e-15	34.51	pep primary_assembly:ASM223467v1:12:1368783:137286...	[more]
syt7a	2.711e-15	35.34	synaptotagmin-7-like [Source:NCBI gene;Acc:1011691...	[more]
syt9b	2.885e-15	35.29	synaptotagmin-9 [Source:NCBI gene;Acc:101171486]	[more]
syt7a	2.922e-15	35.34	synaptotagmin-7-like [Source:NCBI gene;Acc:1011691...	[more]
syt9b	3.318e-15	35.29	synaptotagmin-9 [Source:NCBI gene;Acc:101171486]	[more]

BLAST of Synaptotagmin VIa vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000043595.1	4.264e-11	100.00	SMESG000043595.1	[more]
SMESG000040037.1	1.397e-12	31.82	SMESG000040037.1	[more]
SMESG000040037.1	1.563e-12	31.82	SMESG000040037.1	[more]
SMESG000059797.1	1.712e-11	31.82	SMESG000059797.1	[more]
SMESG000059797.1	1.838e-11	31.82	SMESG000059797.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30022848 ID=SMED30022848|Name=Synaptotagmin VIa|organism=Schmidtea mediterranea sexual|type=transcript|length=1451bp
GTTTGTTTTATCGATTAAATTTTCTGTTTGTATCAACAGCTTTATTGTTC
ACATTTCACAATGGATTTAAATGAGAATGGTGAGGAAATAACTATTATCG
ATGTAATAAAAGATTTGAGAAAGTTATGGCCTTTATCGGTTATATTTCCT
GAAGCTGTGAAAGAAACTCATGAAAAAAAACTAAACTAGAAGATGAATTT
GAGGAACCAGAACCTGAAAGACCTCTTCCCATAATCGGACGTAACATAGA
TCCTGGTATTGACCAAGGATTGGGTTTGATACATTTTTTGTTAAGATATG
AAGTACAAACTAAGACATTAAAAGTAAATATATTCCAAGGAAAGAATTTA
GTGGGAAAAGATCCTCGAGGTACCAGTGATCCATATGCAGTAATAAAATT
TGATCCGAGATTTCGTGATGATTGGTTATACAAAACTGAAGTCAAAATGA
AGACATTAAATCCAGTTTGGAATCATGTATTTGTGTTTTTCAATTTCACT
CACGAGGAACTTGACAGACATAGGATCCATATCACATTATATGACTGGGA
TAAATATGGGGACCATGAGGCACTGGGAGAGGTTTATTATGATCTTAAGA
AGTTACATGGAAAAGATCACGAAGAAAAGGAAGAAGATCAGCCAAATGAA
TACGCAGAATCGTTGAACGTTGAAAAGCTTTCAATTAAAGAATGGGTTGA
AACCACGAATTCGAAATACGGCATTGAAGAACCTCCCAAGGAATTGGAGC
CAATAACCGAAGAAGACGAAAAAGCTGTACAAAAAAGTGCTTCTATGATT
TTCAATGAACACTATGATGAATACGAAGAAATGGAGGAAGAAGACGAAGA
GGAATTAGAATATCAAAACGATGAACCCGATGCAGAGGGAAATATGAATG
GTGATGATGAAGAAAATATACCAACTGTGAATGTGATACGTAGAATTGAA
ATTAAAAAAAATCTTCAGGCTTTGCCAAATTCAAGAAGTGCATATGGAGA
AATTTTGGTATCCCTCGATTATGTAATTAGAAATAGAACTTTGAATGTTA
AGATAATAAAAGCCAGAAATATGATTGATCCAACTAAACGGGCTTTAGTG
CCATACTGTGTTTTAAGGCATTTATTTATCGGCAACGACCGTGAGAAAAC
CAAAAGTATTCATAGGACATCTTACAGATTTTATACAGACACTCCAGTTT
GGAATGAAGAATTTCCTTTGAAAGTTCCACCAAAAAAATTAAAACAAACC
GCAGTTGAAATACAAGTCTTTCATAGCACAAGTGAATCTAAACCAAAAGA
TGATGAACTCGGTCTAATTCGGCTTGGTTTGAAAACATATCCAGCTCAAA
AAGCTCATTATATAGAATTCTTGGGGAATATTGGAAAGCCGATAGAAAAT
TGGCATTTGATAAGGAAGTAAAAAGTCATTCGTTCTTCACTCGTCGGAAA
G

protein sequence of SMED30022848-orf-1

>SMED30022848-orf-1 ID=SMED30022848-orf-1|Name=SMED30022848-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=325bp
MKTLNPVWNHVFVFFNFTHEELDRHRIHITLYDWDKYGDHEALGEVYYDL
KKLHGKDHEEKEEDQPNEYAESLNVEKLSIKEWVETTNSKYGIEEPPKEL
EPITEEDEKAVQKSASMIFNEHYDEYEEMEEEDEEELEYQNDEPDAEGNM
NGDDEENIPTVNVIRRIEIKKNLQALPNSRSAYGEILVSLDYVIRNRTLN
VKIIKARNMIDPTKRALVPYCVLRHLFIGNDREKTKSIHRTSYRFYTDTP
VWNEEFPLKVPPKKLKQTAVEIQVFHSTSESKPKDDELGLIRLGLKTYPA
QKAHYIEFLGNIGKPIENWHLIRK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0007340	acrosome reaction

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0016020	membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000054	dorsal region of the epidermis

Vocabulary: **INTERPRO**
Term	Definition
IPR001565	Synaptotagmin
IPR000008	C2_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

Main menu

Synaptotagmin VIa

Zeng et. al., 2018

▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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