DDB1- and CUL4-associated factor 7

Overview


Name	DDB1- and CUL4-associated factor 7
Smed ID	SMED30022821
Length (bp)	1322

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of DDB1- and CUL4-associated factor 7 (SMED30022821) t-SNE clustered cells

Violin plots show distribution of expression levels for DDB1- and CUL4-associated factor 7 (SMED30022821) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DDB1- and CUL4-associated factor 7 (SMED30022821) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DDB1- and CUL4-associated factor 7 (SMED30022821) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30022821

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X2 cell	SMED30022821	SMESG000069623.1	SmedASXL_019232	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

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Homology

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BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Human
Match: DCAF7 (DDB1 and CUL4 associated factor 7 [Source:HGNC Symbol;Acc:HGNC:30915])

HSP 1 Score: 562.762 bits (1449), Expect = 0.000e+0
Identity = 256/337 (75.96%), Postives = 293/337 (86.94%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKVQ++ LDE+  EF+  +  DH YPTTK+MWIPD KG  PDL ATSGDYLR+WRV    ET LECLLN+NKNSDFCAPLTSFDWNE+DP +LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRV-GETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342

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Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKVQ++ LDE+  EF+  +  DH YPTTK+MWIPD KG  PDL ATSGDYLR+WRV    ET LECLLN+NKNSDFCAPLTSFDWNE+DP +LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRV-GETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Human
Match: DCAF7 (DDB1 and CUL4 associated factor 7 [Source:HGNC Symbol;Acc:HGNC:30915])

HSP 1 Score: 324.324 bits (830), Expect = 4.749e-110
Identity = 159/254 (62.60%), Postives = 181/254 (71.26%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPV 954
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKV         GE                                              ET LECLLN+NKNSDFCAPLTSFDWNE+DP +LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+++LD+RVPCTPV
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKV---------GE---------------------------------------------TETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPV 206

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Human
Match: DCAF7 (DDB1 and CUL4 associated factor 7 [Source:HGNC Symbol;Acc:HGNC:30915])

HSP 1 Score: 171.014 bits (432), Expect = 3.084e-51
Identity = 74/97 (76.29%), Postives = 87/97 (89.69%), Query Frame = 1

Query:  913 EIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            ++++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:   46 KVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 142

HSP 2 Score: 85.1149 bits (209), Expect = 4.016e-19
Identity = 39/78 (50.00%), Postives = 52/78 (66.67%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHL 426
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKV I+ +         ++  +H      I W P    H+
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVVILDVRVPCTPVARLN--NHRACVNGIAWAPHSSCHI 82

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BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Human
Match: WDR59 (WD repeat domain 59 [Source:HGNC Symbol;Acc:HGNC:25706])

HSP 1 Score: 50.0618 bits (118), Expect = 6.681e-6
Identity = 34/133 (25.56%), Postives = 63/133 (47.37%), Query Frame = 1

Query:  664 TGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWD 1062
            +G V T L  H + + D+ +  A    D+  +   D  + ++D++     T+       ++  ++ WNK++AN LAT   +  ++ + D R P T V  L  H   ++G+ W P S   L + ++D     WD
Sbjct:   73 SGEVGTTLQGHTRVISDLDW--AVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAGAS--QVKWNKKNANCLATS--HDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFWD 199

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BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Celegans
Match: swan-2 (Seven WD repeats, AN11 family [Source:UniProtKB/TrEMBL;Acc:Q93759])

HSP 1 Score: 460.685 bits (1184), Expect = 4.473e-160
Identity = 211/342 (61.70%), Postives = 262/342 (76.61%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWS--IRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRT---TQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIY Y AP+ ++S  WS    P +KFRLA+ SFIEEY+NK+ I+ LDE+ GE V  S  DH YP TKIMWIPD KG  PDL ATSGDYLR+WR+  +N   +E LLN+N+ +++CAPLTSFDWNE+D N++GTSSIDTTCT+W LETGQ +G T     + G V+TQLIAHDKEV+DI+F++  G   IFASVGAD S+R+FDLR LEHSTI+YEDP +  LLRLAWN+ D NY+ATF  +S E+++LD+R+PCTPVARL NH   +NG++WAPHS  H+C+  +D QALIWD+  MP+ I DPILAY A  E+NQI WSS  PDWISIC  + LEILRV
Sbjct:  139 RKEIYAYNAPFTLFSHGWSAATDPSRKFRLAVSSFIEEYSNKIHIVQLDEEAGELVHRSTFDHPYPATKIMWIPDQKGTFPDLLATSGDYLRLWRIGTDNNACIESLLNTNRTAEYCAPLTSFDWNELDMNLIGTSSIDTTCTVWQLETGQAIGTTRPTAAIDGTVRTQLIAHDKEVFDISFSR--GSAQIFASVGADGSLRLFDLRRLEHSTIMYEDPQRQPLLRLAWNRNDHNYIATFGQDSKEVLILDLRLPCTPVARLRNHEATINGLSWAPHSGSHICTAGDDYQALIWDVHEMPKPINDPILAYRAQAEVNQIHWSSSFPDWISICSDNKLEILRV 478

[Close]

Query:  193 RKEIYKYEAPWNIYSINWS--IRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRT---TQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIY Y AP+ ++S  WS    P +KFRLA+ SFIEEY+NK+ I+ LDE+ GE V  S  DH YP TKIMWIPD KG  PDL ATSGDYLR+WR+  +N   +E LLN+N+ +++CAPLTSFDWNE+D N++GTSSIDTTCT+W LETGQ +G T     + G V+TQLIAHDKEV+DI+F++  G   IFASVGAD S+R+FDLR LEHSTI+YEDP +  LLRLAWN+ D NY+ATF  +S E+++LD+R+PCTPVARL NH   +NG++WAPHS  H+C+  +D QALIWD+  MP+ I DPILAY A  E+NQI WSS  PDWISIC  + LEILRV
Sbjct:  139 RKEIYAYNAPFTLFSHGWSAATDPSRKFRLAVSSFIEEYSNKIHIVQLDEEAGELVHRSTFDHPYPATKIMWIPDQKGTFPDLLATSGDYLRLWRIGTDNNACIESLLNTNRTAEYCAPLTSFDWNELDMNLIGTSSIDTTCTVWQLETGQAIGTTRPTAAIDGTVRTQLIAHDKEVFDISFSR--GSAQIFASVGADGSLRLFDLRRLEHSTIMYEDPQRQPLLRLAWNRNDHNYIATFGQDSKEVLILDLRLPCTPVARLRNHEATINGLSWAPHSGSHICTAGDDYQALIWDVHEMPKPINDPILAYRAQAEVNQIHWSSSFPDWISICSDNKLEILRV 478

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Celegans
Match: swan-1 (Seven WD repeats, AN11 family [Source:UniProtKB/TrEMBL;Acc:Q93758])

HSP 1 Score: 364.77 bits (935), Expect = 1.082e-123
Identity = 173/343 (50.44%), Postives = 233/343 (67.93%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEE-----YNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTG-NVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            R EIYK+ +   +Y+  WS + D KFRLA+G+  +        NKV I+ L ++ GE V  +     +P   + +IPDP    PDL AT+ D LR+WRV  + + H + ++ +N NS + + LTSFDWNE++P  +G SS+DTTCTI+ +E G  +G+T       +KTQLIAHDK V+DI F K  GGRD FA+VGAD S RMFDLRHL HSTI+YEDPNK  L RL+WNKQ+  ++A F  NS E+ +LD+R+PC  + RL NH G VNG+AWAPHS  H+C+  +D QALIWD+  +PR ++DPILAY+A GE+NQI W  +  +WI+IC+   LEILRV
Sbjct:   47 RCEIYKFTSDQQLYASAWSNKNDIKFRLAVGTVSDVSVNPCAANKVSIVQLKDETGELVETASFPMEFPANAVGFIPDPDNVYPDLIATTSDCLRLWRV-VDGKVHPDAVMINNTNSQYGSALTSFDWNELEPRYIGVSSVDTTCTIYDVEVGCAIGQTKPTAPFTLKTQLIAHDKPVHDIEFAKINGGRDHFATVGADGSARMFDLRHLNHSTIVYEDPNKEKLQRLSWNKQEPYFMALFAENSQEVQILDIRMPCNILCRLRNHTGPVNGIAWAPHSPHHICTAGDDSQALIWDLQQVPRPVDDPILAYSAGGEVNQIHWGPVHSNWIAICFNKTLEILRV 388

[Close]

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEE-----YNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTG-NVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            R EIYK+ +   +Y+  WS + D KFRLA+G+  +        NKV I+ L ++ GE V  +     +P   + +IPDP    PDL AT+ D LR+WRV  + + H + ++ +N NS + + LTSFDWNE++P  +G SS+DTTCTI+ +E G  +G+T       +KTQLIAHDK V+DI F K  GGRD FA+VGAD S RMFDLRHL HSTI+YEDPNK  L RL+WNKQ+  ++A F  NS E+ +LD+R+PC  + RL NH G VNG+AWAPHS  H+C+  +D QALIWD+  +PR ++DPILAY+A GE+NQI W  +  +WI+IC+   LEILRV
Sbjct:   47 RCEIYKFTSDQQLYASAWSNKNDIKFRLAVGTVSDVSVNPCAANKVSIVQLKDETGELVETASFPMEFPANAVGFIPDPDNVYPDLIATTSDCLRLWRV-VDGKVHPDAVMINNTNSQYGSALTSFDWNELEPRYIGVSSVDTTCTIYDVEVGCAIGQTKPTAPFTLKTQLIAHDKPVHDIEFAKINGGRDHFATVGADGSARMFDLRHLNHSTIVYEDPNKEKLQRLSWNKQEPYFMALFAENSQEVQILDIRMPCNILCRLRNHTGPVNGIAWAPHSPHHICTAGDDSQALIWDLQQVPRPVDDPILAYSAGGEVNQIHWGPVHSNWIAICFNKTLEILRV 388

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BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Celegans
Match: lin-53 (Probable histone-binding protein lin-53 [Source:UniProtKB/Swiss-Prot;Acc:P90916])

HSP 1 Score: 58.5362 bits (140), Expect = 4.521e-9
Identity = 63/261 (24.14%), Postives = 111/261 (42.53%), Query Frame = 1

Query:  451 DYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNM--PRAIED-----PILAYTAAG---EINQIQWSSLQPDWISICYTSALEILRV 1203
            DYL+   VP +N  +    L  +    +        WN     ++ ++S D T   W +   Q +    Q     K     H+  V D+A+     G  +F SVG D  + ++D+R       I  D + + +  LA+N      LAT + +   + + D+R     +    +HR  +  V W+PH+   L S   D +  +WD++ +   ++ ED     P L +   G   +I+   W+  +P W+ +C  S   IL+V
Sbjct:  149 DYLKHSAVPRDNTFNPLIRLKGHTKEGY-----GLSWNPNKEGLILSASDDQTVCHWDINANQNVAGELQA----KDVFKGHESVVEDVAWHVLHDG--VFGSVGDDKKLLIWDVRTSTPGHCI--DAHSAEVNCLAFNPYSEFILATGSADKT-VALWDLRNLRMKLHSFESHRDEIFQVQWSPHNETILASSGTDKRLHVWDLSKIGEDQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEP-WV-VCSVSEDNILQV 393

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Fly
Match: wap (gene:FBgn0266848 transcript:FBtr0305147)

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 262/338 (77.51%), Postives = 292/338 (86.39%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAA-GEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKY APW +YS+NWS+RPDK+FRLA+GSFIEEYNNKVQIISLDED  EF A S  DH YPTTKIMWIPD KG  PDL ATSGDYLR+WR     +T LEC+LN+NKNSDFCAPLTSFDWNE+DPN++GTSSIDTTCTIW LETGQ   R   V G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP  +ALLRLAWNKQD NYLAT  ++S E+I+LD+RVPCTPVARL+NHR CVNG+AWAPHSSCH+C+  +D QALIWDI  MPRAIEDPILAYTAA GE+NQIQW + QPDWI+ICY  A EILRV
Sbjct:    8 RKEIYKYLAPWPLYSMNWSVRPDKRFRLALGSFIEEYNNKVQIISLDEDTSEFSAKSTFDHPYPTTKIMWIPDSKGVYPDLLATSGDYLRVWRA-GEPDTRLECVLNNNKNSDFCAPLTSFDWNEVDPNLVGTSSIDTTCTIWGLETGQPHARV-YVAGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPAHTALLRLAWNKQDPNYLATVAMDSCEVIILDVRVPCTPVARLSNHRACVNGIAWAPHSSCHICTAGDDHQALIWDIQQMPRAIEDPILAYTAAEGEVNQIQWGATQPDWIAICYNKACEILRV 343

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Fly
Match: wap (gene:FBgn0266848 transcript:FBtr0309240)

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 262/338 (77.51%), Postives = 292/338 (86.39%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAA-GEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKY APW +YS+NWS+RPDK+FRLA+GSFIEEYNNKVQIISLDED  EF A S  DH YPTTKIMWIPD KG  PDL ATSGDYLR+WR     +T LEC+LN+NKNSDFCAPLTSFDWNE+DPN++GTSSIDTTCTIW LETGQ   R   V G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP  +ALLRLAWNKQD NYLAT  ++S E+I+LD+RVPCTPVARL+NHR CVNG+AWAPHSSCH+C+  +D QALIWDI  MPRAIEDPILAYTAA GE+NQIQW + QPDWI+ICY  A EILRV
Sbjct:    8 RKEIYKYLAPWPLYSMNWSVRPDKRFRLALGSFIEEYNNKVQIISLDEDTSEFSAKSTFDHPYPTTKIMWIPDSKGVYPDLLATSGDYLRVWRA-GEPDTRLECVLNNNKNSDFCAPLTSFDWNEVDPNLVGTSSIDTTCTIWGLETGQPHARV-YVAGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPAHTALLRLAWNKQDPNYLATVAMDSCEVIILDVRVPCTPVARLSNHRACVNGIAWAPHSSCHICTAGDDHQALIWDIQQMPRAIEDPILAYTAAEGEVNQIQWGATQPDWIAICYNKACEILRV 343

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Fly
Match: wap (gene:FBgn0266848 transcript:FBtr0339498)

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 262/338 (77.51%), Postives = 292/338 (86.39%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAA-GEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKY APW +YS+NWS+RPDK+FRLA+GSFIEEYNNKVQIISLDED  EF A S  DH YPTTKIMWIPD KG  PDL ATSGDYLR+WR     +T LEC+LN+NKNSDFCAPLTSFDWNE+DPN++GTSSIDTTCTIW LETGQ   R   V G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP  +ALLRLAWNKQD NYLAT  ++S E+I+LD+RVPCTPVARL+NHR CVNG+AWAPHSSCH+C+  +D QALIWDI  MPRAIEDPILAYTAA GE+NQIQW + QPDWI+ICY  A EILRV
Sbjct:    8 RKEIYKYLAPWPLYSMNWSVRPDKRFRLALGSFIEEYNNKVQIISLDEDTSEFSAKSTFDHPYPTTKIMWIPDSKGVYPDLLATSGDYLRVWRA-GEPDTRLECVLNNNKNSDFCAPLTSFDWNEVDPNLVGTSSIDTTCTIWGLETGQPHARV-YVAGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPAHTALLRLAWNKQDPNYLATVAMDSCEVIILDVRVPCTPVARLSNHRACVNGIAWAPHSSCHICTAGDDHQALIWDIQQMPRAIEDPILAYTAAEGEVNQIQWGATQPDWIAICYNKACEILRV 343

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Fly
Match: wap (gene:FBgn0266848 transcript:FBtr0077368)

HSP 1 Score: 553.903 bits (1426), Expect = 0.000e+0
Identity = 262/338 (77.51%), Postives = 292/338 (86.39%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAA-GEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKY APW +YS+NWS+RPDK+FRLA+GSFIEEYNNKVQIISLDED  EF A S  DH YPTTKIMWIPD KG  PDL ATSGDYLR+WR     +T LEC+LN+NKNSDFCAPLTSFDWNE+DPN++GTSSIDTTCTIW LETGQ   R   V G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP  +ALLRLAWNKQD NYLAT  ++S E+I+LD+RVPCTPVARL+NHR CVNG+AWAPHSSCH+C+  +D QALIWDI  MPRAIEDPILAYTAA GE+NQIQW + QPDWI+ICY  A EILRV
Sbjct:    8 RKEIYKYLAPWPLYSMNWSVRPDKRFRLALGSFIEEYNNKVQIISLDEDTSEFSAKSTFDHPYPTTKIMWIPDSKGVYPDLLATSGDYLRVWRA-GEPDTRLECVLNNNKNSDFCAPLTSFDWNEVDPNLVGTSSIDTTCTIWGLETGQPHARV-YVAGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPAHTALLRLAWNKQDPNYLATVAMDSCEVIILDVRVPCTPVARLSNHRACVNGIAWAPHSSCHICTAGDDHQALIWDIQQMPRAIEDPILAYTAAEGEVNQIQWGATQPDWIAICYNKACEILRV 343

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Zebrafish
Match: dcaf7 (ddb1 and cul4 associated factor 7 [Source:ZFIN;Acc:ZDB-GENE-030131-9511])

HSP 1 Score: 565.459 bits (1456), Expect = 0.000e+0
Identity = 259/337 (76.85%), Postives = 295/337 (87.54%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKVQ++ L+E+  EFV  +  DH YPTTKIMWIPD KG  PDL ATSGDYLRIWRV  + ET LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLEEESSEFVCRNTFDHPYPTTKIMWIPDTKGVYPDLLATSGDYLRIWRV-NDTETRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Zebrafish
Match: daw1 (dynein assembly factor with WDR repeat domains 1 [Source:NCBI gene;Acc:556760])

HSP 1 Score: 53.5286 bits (127), Expect = 2.699e-7
Identity = 40/170 (23.53%), Postives = 75/170 (44.12%), Query Frame = 1

Query:  418 GHLPDL----FATSGDYLR---------IWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYL 888
            GH  ++    F T+GD L          +W VP+  + H+   L+ ++    C     F+W   D +++ T+S+D +C +W  E GQ +             L+ H+ EV D+ F   G    + A+  AD + R+F     +   +   + +K  + ++ +N Q +  L
Sbjct:  217 GHFAEIISLCFNTTGDRLVTGSFDHTAILWDVPSGRKVHV---LSGHRGEISCV---QFNW---DCSLIATASLDKSCKVWDAEGGQCLA-----------TLLGHNDEVLDVCFNYTG---QLIATASADGTSRVFSTDTFQ--CLCQLEGHKGEISKVCFNAQGSRVL 361

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Zebrafish
Match: daw1 (dynein assembly factor with WDR repeat domains 1 [Source:NCBI gene;Acc:556760])

HSP 1 Score: 53.5286 bits (127), Expect = 3.020e-7
Identity = 40/170 (23.53%), Postives = 75/170 (44.12%), Query Frame = 1

Query:  418 GHLPDL----FATSGDYLR---------IWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYL 888
            GH  ++    F T+GD L          +W VP+  + H+   L+ ++    C     F+W   D +++ T+S+D +C +W  E GQ +             L+ H+ EV D+ F   G    + A+  AD + R+F     +   +   + +K  + ++ +N Q +  L
Sbjct:  217 GHFAEIISLCFNTTGDRLVTGSFDHTAILWDVPSGRKVHV---LSGHRGEISCV---QFNW---DCSLIATASLDKSCKVWDAEGGQCLA-----------TLLGHNDEVLDVCFNYTG---QLIATASADGTSRVFSTDTFQ--CLCQLEGHKGEISKVCFNAQGSRVL 361

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Zebrafish
Match: grwd1 (glutamate-rich WD repeat containing 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9844])

HSP 1 Score: 51.6026 bits (122), Expect = 1.289e-6
Identity = 61/271 (22.51%), Postives = 106/271 (39.11%), Query Frame = 1

Query:  457 LRIWRVPANNETHLECLLNSNKNSDFCAPLTSF----------DWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAP-HSSCHLCSGAEDCQALIWDIT----NMPRAIED-----PILAYTAAG--EINQIQWSSLQPDWISICYTSALEILRV 1203
            LR+     +N T +   +   K +    PL SF          DW+   P  + +        +W  + G     T ++    +    +H K V D+ ++       +FAS   D S+R++D+R   +S +   + + S +  ++WN+ +   L+       ++  L       PVA    H   V  V W+P  SS    SGA+D  +  WD++    +M    ED     P L +   G  E+ ++ W    P  +     S   I R 
Sbjct:  192 LRLQLEAVHNSTAMSAFIKQEKEA---TPLFSFAGHMSEGFAIDWSPKVPGRMVSGDCKKNIHVWEPQEG----GTWKID---QRPFSSHSKSVEDLQWSPTEA--TVFASCSVDQSIRIWDIRAPPNSMLSANEAHSSDVNVISWNRTEPFILSGGDDGLLKVWDLRQFQSGRPVASFKQHSAPVTSVQWSPVDSSVFAASGADDVISQ-WDLSVESCDMGGQAEDVKQLPPQLLFLHQGQKEVKELHWHPQIPGVLISTALSGFNIFRT 449

[Close]

Query:  457 LRIWRVPANNETHLECLLNSNKNSDFCAPLTSF----------DWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAP-HSSCHLCSGAEDCQALIWDIT----NMPRAIED-----PILAYTAAG--EINQIQWSSLQPDWISICYTSALEILRV 1203
            LR+     +N T +   +   K +    PL SF          DW+   P  + +        +W  + G     T ++    +    +H K V D+ ++       +FAS   D S+R++D+R   +S +   + + S +  ++WN+ +   L+       ++  L       PVA    H   V  V W+P  SS    SGA+D  +  WD++    +M    ED     P L +   G  E+ ++ W    P  +     S   I R 
Sbjct:  192 LRLQLEAVHNSTAMSAFIKQEKEA---TPLFSFAGHMSEGFAIDWSPKVPGRMVSGDCKKNIHVWEPQEG----GTWKID---QRPFSSHSKSVEDLQWSPTEA--TVFASCSVDQSIRIWDIRAPPNSMLSANEAHSSDVNVISWNRTEPFILSGGDDGLLKVWDLRQFQSGRPVASFKQHSAPVTSVQWSPVDSSVFAASGADDVISQ-WDLSVESCDMGGQAEDVKQLPPQLLFLHQGQKEVKELHWHPQIPGVLISTALSGFNIFRT 449

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Xenopus
Match: dcaf7 (DDB1 and CUL4 associated factor 7 [Source:NCBI gene;Acc:394701])

HSP 1 Score: 565.459 bits (1456), Expect = 0.000e+0
Identity = 257/337 (76.26%), Postives = 294/337 (87.24%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKVQ++ LDE+  EF+  +  DH YPTTK+MWIPD KG  PDL ATSGDYLR+WRV    ET LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRV-GETETRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Mouse
Match: Dcaf7 (DDB1 and CUL4 associated factor 7 [Source:MGI Symbol;Acc:MGI:1919083])

HSP 1 Score: 562.762 bits (1449), Expect = 0.000e+0
Identity = 256/337 (75.96%), Postives = 293/337 (86.94%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKVQ++ LDE+  EF+  +  DH YPTTK+MWIPD KG  PDL ATSGDYLR+WRV    ET LECLLN+NKNSDFCAPLTSFDWNE+DP +LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRV-GETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Mouse
Match: Wdr59 (WD repeat domain 59 [Source:MGI Symbol;Acc:MGI:2442115])

HSP 1 Score: 50.447 bits (119), Expect = 4.725e-6
Identity = 34/133 (25.56%), Postives = 63/133 (47.37%), Query Frame = 1

Query:  664 TGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWD 1062
            +G V T L  H + + D+ +  A    D+  +   D  + ++D++     T+       ++ ++  WNK++ANYLAT   +  ++ + D R P T V  L  H   ++G+ W P S     + ++D     WD
Sbjct:   94 SGEVGTTLQGHTRVISDLDW--AVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAGASQVK--WNKKNANYLATS--HDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHIFATSSQDNSVKFWD 220

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Mouse
Match: Wdr59 (WD repeat domain 59 [Source:MGI Symbol;Acc:MGI:2442115])

HSP 1 Score: 50.0618 bits (118), Expect = 5.265e-6
Identity = 36/139 (25.90%), Postives = 65/139 (46.76%), Query Frame = 1

Query:  664 TGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPR 1080
            +G V T L  H + + D+ +  A    D+  +   D  + ++D++     T+       ++ ++  WNK++ANYLAT   +  ++ + D R P T V  L  H   ++G+ W P S     + ++D     WD    PR
Sbjct:   94 SGEVGTTLQGHTRVISDLDW--AVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAGASQVK--WNKKNANYLATS--HDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHIFATSSQDNSVKFWDY-RQPR 225

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Mouse
Match: Wdr59 (WD repeat domain 59 [Source:MGI Symbol;Acc:MGI:2442115])

HSP 1 Score: 50.0618 bits (118), Expect = 5.713e-6
Identity = 36/139 (25.90%), Postives = 65/139 (46.76%), Query Frame = 1

Query:  664 TGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPR 1080
            +G V T L  H + + D+ +  A    D+  +   D  + ++D++     T+       ++ ++  WNK++ANYLAT   +  ++ + D R P T V  L  H   ++G+ W P S     + ++D     WD    PR
Sbjct:   94 SGEVGTTLQGHTRVISDLDW--AVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAGASQVK--WNKKNANYLATS--HDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHIFATSSQDNSVKFWDY-RQPR 225

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. UniProt/SwissProt
Match: sp|P61963|DCAF7_MOUSE (DDB1- and CUL4-associated factor 7 OS=Mus musculus OX=10090 GN=Dcaf7 PE=1 SV=1)

HSP 1 Score: 562.762 bits (1449), Expect = 0.000e+0
Identity = 256/337 (75.96%), Postives = 293/337 (86.94%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKVQ++ LDE+  EF+  +  DH YPTTK+MWIPD KG  PDL ATSGDYLR+WRV    ET LECLLN+NKNSDFCAPLTSFDWNE+DP +LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRV-GETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. UniProt/SwissProt
Match: sp|P61962|DCAF7_HUMAN (DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1)

HSP 1 Score: 562.762 bits (1449), Expect = 0.000e+0
Identity = 256/337 (75.96%), Postives = 293/337 (86.94%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKVQ++ LDE+  EF+  +  DH YPTTK+MWIPD KG  PDL ATSGDYLR+WRV    ET LECLLN+NKNSDFCAPLTSFDWNE+DP +LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRV-GETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. UniProt/SwissProt
Match: sp|Q552R1|DCAF7_DICDI (DDB1- and CUL4-associated factor 7 homolog OS=Dictyostelium discoideum OX=44689 GN=wdr68 PE=3 SV=2)

HSP 1 Score: 414.846 bits (1065), Expect = 3.314e-143
Identity = 198/338 (58.58%), Postives = 254/338 (75.15%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNET-HLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            +K IY Y +PW IY ++WS R ++ FRLAIGSF+E+Y N+V +I L+E+  +F  V   +H YP TK MWIPD   + PDL AT+GDYLR+W V +N  +  L+ LL +N  S+FCAPL+SFDWNE DP++L TSSIDTTCTIW++ETGQ            KTQLIAHDKEV+DIAF +   G D+FASVGAD S+RMFDLR+LEHSTIIYE P+   LLRL WNKQD NYLAT   +SP++I+LD+RVP  P A L  H+  VNG++WAPHSSCH+C+ ++D QALIWD+++MP+ IEDP+L Y A  EINQ+ WSS QPDWI+I ++S L+IL+V
Sbjct:    3 KKRIYTYNSPWVIYGLSWSSRVNRPFRLAIGSFLEDYTNRVDVIQLNEETDQFEVVCGFEHPYPPTKCMWIPDKNSNRPDLLATTGDYLRLWEVGSNQRSIKLKSLL-TNVISEFCAPLSSFDWNETDPSLLATSSIDTTCTIWNIETGQA-----------KTQLIAHDKEVFDIAFAR---GTDLFASVGADGSLRMFDLRNLEHSTIIYETPSFVPLLRLCWNKQDPNYLATIQQDSPKVIILDIRVPSVPAAELVFHKSAVNGISWAPHSSCHICTVSDDKQALIWDLSSMPKPIEDPLLTYNALAEINQLSWSSSQPDWIAIAFSSHLQILKV 325

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. UniProt/SwissProt
Match: sp|Q9LPV9|LWD1_ARATH (WD repeat-containing protein LWD1 OS=Arabidopsis thaliana OX=3702 GN=LWD1 PE=2 SV=1)

HSP 1 Score: 386.726 bits (992), Expect = 7.654e-132
Identity = 189/344 (54.94%), Postives = 243/344 (70.64%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVS--CVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPAN-NETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPN-KSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIE---DPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            R EIY YEAPW+IY++NWS+R DKK+RLAI S +E+Y N+V+I+ LDE  GE  +      +H YP TK ++IPD +   PDL ATS D+LR+WR+  + +   L+  LNSNKNS+FC PLTSFDWNE +P  +GTSS DTTCTIW +E   V            TQLIAHDKEV+DIA+    GG  +FASV AD SVR+FDLR  EHSTIIYE     + L+RL WNKQD  Y+AT  ++S +++VLD+R P  PV  L  H+  VN +AWAPHSSCH+C+  +D QALIWDI++M + +E   DPILAYTA  EI Q+QWSS QPDW++I +++ L+ILRV
Sbjct:   18 RSEIYTYEAPWHIYAMNWSVRRDKKYRLAITSLLEQYPNRVEIVQLDESNGEIRSDPNLSFEHPYPPTKTIFIPDKECQRPDLLATSSDFLRLWRIADDHSRVELKSCLNSNKNSEFCGPLTSFDWNEAEPRRIGTSSTDTTCTIWDIEREAV-----------DTQLIAHDKEVFDIAW----GGVGVFASVSADGSVRVFDLRDKEHSTIIYESSEPDTPLVRLGWNKQDPRYMATIIMDSAKVVVLDIRFPALPVVELQRHQASVNAIAWAPHSSCHICTAGDDSQALIWDISSMGQHVEGGLDPILAYTAGAEIEQLQWSSSQPDWVAIAFSTKLQILRV 346

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. UniProt/SwissProt
Match: sp|Q38960|LWD2_ARATH (WD repeat-containing protein LWD2 OS=Arabidopsis thaliana OX=3702 GN=LWD2 PE=2 SV=1)

HSP 1 Score: 382.489 bits (981), Expect = 3.390e-130
Identity = 190/344 (55.23%), Postives = 240/344 (69.77%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVS--CVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPAN-NETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSA-LLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIE---DPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            R EIY YEAPW IY++NWSIR DKK+RLAI S IE+Y N+V+I+ LDE  GE  +    C +H YP TK  +IPD +   PDL ATS D+LR+WR+  + +   L+  L+S+KNS+F  P+TSFDWNE +P  +GTSSIDTTCTIW +E   V            TQLIAHDKEVYDIA+    GG  +FASV  D SVR+FDLR  EHSTIIYE    S  L+RL+WNKQD  Y+AT  + S +I+VLD+R P  PV  L  H+  VN +AWAPHSS H+CS  +D QALIWDI++M + +E   DPILAYTA  E+ Q+QWSS QPDW++I +++ L+ILRV
Sbjct:   18 RSEIYTYEAPWQIYAMNWSIRRDKKYRLAITSLIEQYPNRVEIVQLDESNGEIRSDPNLCFEHPYPPTKTSFIPDKECQRPDLLATSSDFLRLWRISDDESRVELKSCLSSDKNSEFSGPITSFDWNEAEPRRIGTSSIDTTCTIWDIEREVV-----------DTQLIAHDKEVYDIAW----GGVGVFASVSEDGSVRVFDLRDKEHSTIIYESGEPSTPLVRLSWNKQDPRYMATVIMGSAKIVVLDIRFPALPVVELQRHQASVNAIAWAPHSSSHICSAGDDSQALIWDISSMGQHVEGGLDPILAYTAGAEVEQLQWSSSQPDWVAIAFSNKLQILRV 346

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. TrEMBL
Match: A0A210Q3D8 (DDB1-and CUL4-associated factor 7 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT18795 PE=4 SV=1)

HSP 1 Score: 586.26 bits (1510), Expect = 0.000e+0
Identity = 268/337 (79.53%), Postives = 300/337 (89.02%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +YS+NWSIRPDK+FRLA+GSF+EEYNNKVQI+SLDE+  EF + S  DH YPTTKIMWIPD KG  PDL ATSGDYLR+WRV ++N+T LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++S E+I+LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI +MPRAIEDPILAYTA GEINQ QWSS QPDWISICY + LEILRV
Sbjct:   29 RKEIYKYEAPWTVYSMNWSIRPDKRFRLALGSFVEEYNNKVQIVSLDEETSEFTSKSTFDHPYPTTKIMWIPDSKGVFPDLLATSGDYLRVWRVSSDNDTRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNVVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLGWNKQDPNYLATMAMDSLEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQSMPRAIEDPILAYTAGGEINQTQWSSTQPDWISICYNNCLEILRV 365

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. TrEMBL
Match: K1QTB8 (WD repeat-containing protein 68 OS=Crassostrea gigas OX=29159 GN=CGI_10027101 PE=4 SV=1)

HSP 1 Score: 582.022 bits (1499), Expect = 0.000e+0
Identity = 267/337 (79.23%), Postives = 300/337 (89.02%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +YS+NWSIRPDK+FRLA+GSF+EEYNNKVQI+SLDE+  EF + S  DH YPTTKIMWIPD KG  PDL ATSGDYLR+WRV + NE+ LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYED     LLRL WNKQD NYLAT  +++ E+I+LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI +MPRAIEDPILAYTAAGEINQIQWSS QPDWI+ICY + LEILRV
Sbjct:  625 RKEIYKYEAPWTVYSMNWSIRPDKRFRLALGSFVEEYNNKVQIVSLDEETSEFTSKSTFDHPYPTTKIMWIPDAKGGYPDLLATSGDYLRVWRV-SENESRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNVVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDAQHHPLLRLCWNKQDPNYLATMAMDAMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQSMPRAIEDPILAYTAAGEINQIQWSSTQPDWIAICYNNCLEILRV 960

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. TrEMBL
Match: A0A1S3JL82 (DDB1- and CUL4-associated factor 7 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106173890 PE=4 SV=1)

HSP 1 Score: 580.482 bits (1495), Expect = 0.000e+0
Identity = 269/337 (79.82%), Postives = 301/337 (89.32%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +YS+NWS+RPDK+FRLA+GSF+EEYNNKVQI SLDE+  EFVA S  DH YPTTKIMWIPD KG  PDL ATSGDYLR+WRV  ++ET LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR   VTG+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRLAWNKQD NYLAT  +++ E+I+LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYT++GEINQIQWSS QPDWI+ICY + LEILRV
Sbjct:   17 RKEIYKYEAPWILYSMNWSVRPDKRFRLAVGSFVEEYNNKVQIASLDEETSEFVARSTFDHPYPTTKIMWIPDTKGVYPDLLATSGDYLRVWRV-GDSETRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNLVTGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLAWNKQDPNYLATMAMDAMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTSSGEINQIQWSSTQPDWIAICYNNCLEILRV 352

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. TrEMBL
Match: A0A023GJ78 (Putative ddb1-and cul4-associated factor 7 (Fragment) OS=Amblyomma triste OX=251400 PE=2 SV=1)

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 269/341 (78.89%), Postives = 300/341 (87.98%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQ----VTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +YS+NWS+RPD++FRLA+GSFIEEYNNKVQ++SLDED  EF+A S  DH YPTTKIMWIPD KG  PDL ATSGDYLR+WR  A  ET LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR       V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRLAWNKQD NYLATF +++ E+I+LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEINQIQW+S QPDWI+ICY S LEILRV
Sbjct:   36 RKEIYKYEAPWTVYSMNWSVRPDRRFRLALGSFIEEYNNKVQLVSLDEDTSEFLAKSTFDHPYPTTKIMWIPDTKGVFPDLLATSGDYLRVWR--AGEETRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVVGRAMAGGGAVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHQPLLRLAWNKQDPNYLATFAMDACEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINQIQWASTQPDWIAICYNSCLEILRV 374

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. TrEMBL
Match: A0A2T7PIZ7 (WD_REPEATS_REGION domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_04662 PE=4 SV=1)

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 266/337 (78.93%), Postives = 298/337 (88.43%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIY+YEAPW +YS+NWSIRPDK+FRLA+GSF+EEYNNKVQI+SLDE+  EF A S  DH YPTTKIMWIPD KG  PDL ATSGDYLR+WRV  ++ET LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRLAWNKQD NYLAT  +++ E+I+LD+RVPCTPVARLNNHR CVNG+ WAPHSSCH+C+  +D QALIWDI  MPRAIEDPILAYTA GEINQIQWSS QPDWISICY + +EILRV
Sbjct:   12 RKEIYRYEAPWTVYSMNWSIRPDKRFRLALGSFVEEYNNKVQIVSLDEESAEFTAKSTFDHPYPTTKIMWIPDSKGVFPDLMATSGDYLRVWRV-GDSETRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNMVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPGHVPLLRLAWNKQDPNYLATMAMDALEVIILDVRVPCTPVARLNNHRACVNGIGWAPHSSCHICTAGDDHQALIWDIQQMPRAIEDPILAYTAGGEINQIQWSSTQPDWISICYNNCMEILRV 347

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Cavefish
Match: dcaf7 (DDB1 and CUL4 associated factor 7 [Source:NCBI gene;Acc:103044748])

HSP 1 Score: 567 bits (1460), Expect = 0.000e+0
Identity = 260/337 (77.15%), Postives = 295/337 (87.54%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKVQ++ LDE+  EFV  +  DH YPTTKIMWIPD KG  PDL ATSGDYLRIWRV  + ET LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFVCRNTFDHPYPTTKIMWIPDTKGVYPDLLATSGDYLRIWRV-NDTETRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Cavefish
Match: sec31b (protein transport protein Sec31A-like [Source:NCBI gene;Acc:103026503])

HSP 1 Score: 51.6026 bits (122), Expect = 1.607e-6
Identity = 47/184 (25.54%), Postives = 82/184 (44.57%), Query Frame = 1

Query:  517 NKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANY--LATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWD 1062
             ++S    P+ + D+N    N+L + + D+   IW L        +  +T   K+QL    ++V  +A+ K    + I AS G      ++DLR  E    I +  N+     + W+ + A    LA+     P I + D+R   +P+  L NH   +  V+W+      L S A+D + L W+
Sbjct:  115 GQSSKHTGPVRALDYNHFQSNLLASGANDSEMFIWDLNN-----FSNPMTPGSKSQLNELVEDVCVVAWNKQV--QHILASAGPSGRAVVWDLRKNEPIIKISDHSNRMHCSGMLWHPEVATQMILASEDDRLPVIQMWDLRFATSPLKVLENHTRGILSVSWSQADPELLLSSAKDNRILCWN 291

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Cavefish
Match: rbbp4 (RB binding protein 4, chromatin remodeling factor [Source:NCBI gene;Acc:103039809])

HSP 1 Score: 49.2914 bits (116), Expect = 6.047e-6
Identity = 56/232 (24.14%), Postives = 100/232 (43.10%), Query Frame = 1

Query:  550 SFDWNEIDPNILG---TSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYE-DPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNM-----PRAIED--PILAYTAAG---EINQIQWSSLQPDWISICYTSALEILRV 1203
               WN   PN+ G   ++S D T  +W + T    G+      + KT    H   V D+++        +F SV  D  + ++D R    S   +  D + + +  L++N      LAT + +   + + D+R     +    +H+  +  V W+PH+   L S   D +  +WD++ +     P   ED  P L +   G   +I+   W+  +P W+ IC  S   I++V
Sbjct:  182 GLSWN---PNLSGCLLSASDDHTICLWDISTVPKEGKIV----DAKTIFTGHTAVVEDVSWHLLH--ESLFGSVADDQKLMIWDTRSNNTSKPSHAVDAHTAEVNCLSFNPYSEFILATGSADK-TVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEP-WV-ICSVSEDNIMQV 401

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Cavefish
Match: pex7 (peroxisomal biogenesis factor 7 [Source:NCBI gene;Acc:103024267])

HSP 1 Score: 48.521 bits (114), Expect = 7.442e-6
Identity = 43/181 (23.76%), Postives = 79/181 (43.65%), Query Frame = 1

Query:  550 SFDWNEI-DPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIE 1089
            S DW++    N++ + S D T  +W  E  Q +             L  H+  +Y   ++        FAS   D ++R++D++    S  +    +K+ +L   W K D N L T +++   + V D+R    PVA++ +H   +  V ++P     L S + D     WD +  P  ++
Sbjct:  108 SVDWSQTRGENLVVSGSWDHTAKVWDPERFQSV-----------CTLQGHEGVLYSTIWSPHISS--CFASASGDGTLRVWDVK--SGSCRMAIPAHKTEILSCDWCKYDQNILVTGSVDC-SLCVWDLRTVRQPVAQMLSHTYAIRRVKFSPFYKTVLASCSYDFTVRFWDYSRSPMLLD 272

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Sea Lamprey
Match: DCAF7 (DDB1 and CUL4 associated factor 7 [Source:HGNC Symbol;Acc:HGNC:30915])

HSP 1 Score: 491.115 bits (1263), Expect = 2.408e-175
Identity = 227/297 (76.43%), Postives = 258/297 (86.87%), Query Frame = 1

Query:  313 VQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            +Q++ LDE+  EFV  S  DH YPTTK+MWIPD KG  PDL ATSGDYLR+WRV +++ET LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+I+LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:    1 LQVVGLDEESSEFVCKSTFDHPYPTTKVMWIPDTKGVFPDLVATSGDYLRVWRV-SDSETRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHRPLLRLCWNKQDPNYLATMAMDGLEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 296

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008002.1 (pep scaffold:Pmarinus_7.0:GL477852:421:9512:1 gene:ENSPMAG00000007189.1 transcript:ENSPMAT00000008002.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.447 bits (119), Expect = 4.840e-7
Identity = 82/368 (22.28%), Postives = 145/368 (39.40%), Query Frame = 1

Query:  253 RPDKK----FRLAIGSFIEEYNNKVQIISL--------------DEDKGEFVAVSCV----------DHLYPTTKIMWIPDPKGHLPDLFATSG--------DYLRIWRVP-ANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILG---TSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYE-DPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNM--PRAIED-----PILAYTAAG---EINQIQWSSLQPDWISICYTSALEILRV 1203
            RP+ K     RL +G+   +  N + I S+              D +KGEF     V          +H     +  ++P      P + AT          DY +   VP  + E + +  L  ++   +        WN   PN+ G   ++S D T  +W +      G+  +     KT    H   V D+++        +F SV  D  + ++D R    S   +  D + + +  L++N      LAT + +   + + D+R     +    +HR  +  V W+PH+   L S   D +  +WD++ +   +A ED     P L +   G   +I+   W+  +P W+ IC  S   I++V
Sbjct:   55 RPEGKDYSVHRLILGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVGTKIEVEIKINHEGEVNRARYMP----QNPYIIATKTPTSEVLVFDYTKHPSVPDPSGECNPDLRLRGHQKEGY-----GLSWN---PNLSGHLLSASDDHTVCLWDISGTPREGKVVEA----KTIFTGHTAVVEDVSWHLLH--ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADQ-TVALWDLRNLKLKLHSFESHRDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQAAEDVEDGPPELLFVHGGHTAKISDFSWNPNEP-WV-ICSVSEDNIMQV 401

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Yeast
Match: YPL247C_mRNA (Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; similar to the petunia WD repeat protein an11; overexpression causes a cell cycle delay or arrest [Source:SGD;Acc:S000006168])

HSP 1 Score: 190.274 bits (482), Expect = 2.525e-55
Identity = 121/324 (37.35%), Postives = 167/324 (51.54%), Query Frame = 1

Query:  199 EIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLE------CLLNSNKNSDFCA-----------PLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAF-TKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKS-----------------ALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDI 1065
             + +Y++ + ++ ++WS        + +GS+ E+  NK+Q++    D   + +V   D +YP +KI W+P      P   AT  D LRIW V        E      C  N    ++  A           P+TSFDWN +D N++ +SSIDTTC +W L++             VKTQLIAHD EV+D+ F TK+     +FAS G D SVR+FDLR L HSTIIYE P+ S                 ALLRL  +  D N LATF  +S +II+LDMR P +P+  L  H   VNG+ W P     L S  +DCQ L WD+
Sbjct:  121 SVCEYQSHYPLFGLDWS----ADDYVCLGSYKEDSRNKLQVLH-SNDLLSWESVVDADVVYPVSKIQWVP--SQLYPRKLATCSDSLRIWSVSPEERQFQEQINLSLCKYNRQHPANPAAADDMKVIGTFPPITSFDWNTVDTNLIISSSIDTTCIVWDLQSSHY----------VKTQLIAHDSEVFDVRFLTKS---TQLFASCGGDGSVRVFDLRSLAHSTIIYEPPSSSVSGATAGTITPSSKGSDALLRLEPSPYDPNVLATFAADSNKIIILDMRNPESPILNLQGHGSSVNGIKWHPTKRNVLLSCGDDCQVLYWDL 424

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Yeast
Match: MTC5 (Subunit of SEACAT, a subcomplex of the SEA complex; Mtc1p, along with Rtc1p and Sea4p, redundantly inhibit the TORC1 inhibitory role of the Iml1p/SEACIT (Iml1p-Npr2p-Npr3p) subcomplex, a GAP for GTPase Gtr1p (EGOC subunit) in response to amino acid limitation, thereby resulting in activation of TORC1 signaling; SEA is a coatomer-related complex that associates dynamically with the vacuole; relative distribution to the vacuolar membrane decreases upon DNA replication stress [Source:SGD;Acc:S000002535])

HSP 1 Score: 49.2914 bits (116), Expect = 1.004e-6
Identity = 35/128 (27.34%), Postives = 54/128 (42.19%), Query Frame = 1

Query:  685 LIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDIT 1068
            L  H + + DI F       D+ A+   D  V  +D+R   H         +SA  ++ WN +D N LA+   N  +I V D+R   TP+  L  H   VN + +       + S + D     WD +
Sbjct:  110 LHGHSRAITDINFNPQHP--DVLATCSVDTYVHAWDMRS-PHRPFYSTSSWRSAASQVKWNYKDPNVLASSHGN--DIFVWDLRKGSTPLCSLKGHVSSVNSIDFNRFKYSEIMSSSNDGTVKFWDYS 232

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Yeast
Match: RRB1 (Specific chaperone for ribosomal protein Rpl3p; binds to nascent Rpl3p during translation; essential gene [Source:SGD;Acc:S000004738])

HSP 1 Score: 48.1358 bits (113), Expect = 1.674e-6
Identity = 31/134 (23.13%), Postives = 65/134 (48.51%), Query Frame = 1

Query:  688 IAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRV-------PCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDIT 1068
            ++++K + DI +++      +FA+ G D  +R++D R  +H   I    + + +  ++W+ +    LA+   N     V D+R           PVA+ + H+G +  +A+ P     +  G+ED    +WD++
Sbjct:  318 VSNNKSIEDIQWSRTEST--VFATAGCDGYIRIWDTRSKKHKPAISVKASNTDVNVISWSDKIGYLLASGDDNG-TWGVWDLRQFTPSNADAVQPVAQYDFHKGAITSIAFNPLDESIVAVGSEDNTVTLWDLS 448

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Nematostella
Match: EDO44974 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU89])

HSP 1 Score: 563.918 bits (1452), Expect = 0.000e+0
Identity = 260/338 (76.92%), Postives = 297/338 (87.87%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDP-KGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW IY +NWS+R DK+FRLA+GSF+EEYNNKVQI+ LDE+ GEF   S  DH YPTTKI+WIPD  +   PDL ATSGDYLR+WRV  +++  LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP  S LLRL+WNKQD NYLATF+L++ E+I+LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+  +D QALIWDI  MPRAIEDPILAYTA GEINQIQW++ QPDWI+ICY  +LEILRV
Sbjct:   15 RKEIYKYEAPWTIYGMNWSVRTDKRFRLALGSFVEEYNNKVQIVMLDEETGEFTVRSTFDHPYPTTKIIWIPDNVRNSYPDLVATSGDYLRVWRV-GDSDVRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNMVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHSPLLRLSWNKQDPNYLATFSLDAMEVIILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAGDDHQALIWDIQQMPRAIEDPILAYTADGEINQIQWATTQPDWIAICYNKSLEILRV 351

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Medaka
Match: DCAF7 (DDB1 and CUL4 associated factor 7 [Source:NCBI gene;Acc:101173305])

HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0
Identity = 259/337 (76.85%), Postives = 296/337 (87.83%), Query Frame = 1

Query:  193 RKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            RKEIYKYEAPW +Y++NWS+RPDK+FRLA+GSF+EEYNNKVQ++ L+E+  EFV  +  DH YPTTKIMWIPD KG  PDL ATSGDYLRIWRV ++ ET LECLLN+NKNSDFCAPLTSFDWNE+DPN+LGTSSIDTTCTIW LETGQV+GR   V+G+VKTQLIAHDKEVYDIAF++AGGGRD+FASVGAD SVRMFDLRHLEHSTIIYEDP    LLRL WNKQD NYLAT  ++  E+++LD+RVPCTPVARLNNHR CVNG+AWAPHSSCH+C+ A+D QALIWDI  MPRAIEDPILAYTA GEIN +QW+S QPDWI+ICY + LEILRV
Sbjct:    7 RKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLEEESSEFVCRNTFDHPYPTTKIMWIPDTKGVYPDLLATSGDYLRIWRV-SDTETRLECLLNNNKNSDFCAPLTSFDWNEVDPNLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGEINNVQWASTQPDWIAICYNNCLEILRV 342

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Medaka
Match: rbb4l (histone-binding protein RBBP7 [Source:NCBI gene;Acc:101156710])

HSP 1 Score: 50.447 bits (119), Expect = 2.329e-6
Identity = 56/229 (24.45%), Postives = 101/229 (44.10%), Query Frame = 1

Query:  559 WNEIDPNILG---TSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYE-DPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNM--PRAIED-----PILAYTAAG---EINQIQWSSLQPDWISICYTSALEILRV 1203
            WN   PN+ G   ++S D T  +W +  G   G+      + KT    H   V D+++        +F SV  D  + ++D R    S   +  D + + +  L++N      LAT + +   + + D+R     +    +H+  +  V W+PH+   L S   D +  +WD++ +   ++ ED     P L +   G   +I+   W+  +P WI IC  S   I++V
Sbjct:  222 WN---PNLSGNLLSASDDHTICLWDIGAGPKEGKVV----DAKTIFTGHTAVVEDVSWHLLH--ESLFGSVADDQKLMIWDTRSNNTSKASHSVDAHTAEVNCLSFNPYSEFILATGSADK-TVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPGEP-WI-ICSVSEDNIMQV 438

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Medaka
Match: rbbp4 (RB binding protein 4, chromatin remodeling factor [Source:NCBI gene;Acc:101155071])

HSP 1 Score: 49.2914 bits (116), Expect = 5.553e-6
Identity = 56/229 (24.45%), Postives = 100/229 (43.67%), Query Frame = 1

Query:  559 WNEIDPNILG---TSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYE-DPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNM-----PRAIED--PILAYTAAG---EINQIQWSSLQPDWISICYTSALEILRV 1203
            WN   PN+ G   ++S D T  +W + T    G+      + KT    H   V D+++        +F SV  D  + ++D R    S   +  D + + +  L++N      LAT + +   + + D+R     +    +H+  +  V W+PH+   L S   D +  +WD++ +     P   ED  P L +   G   +I+   W+  +P W+ IC  S   I++V
Sbjct:  185 WN---PNLSGCLLSASDDHTICLWDISTVPKEGKIV----DAKTIFTGHTAVVEDVSWHLLH--ESLFGSVADDQKLMIWDTRSNNTSKPSHAVDAHTAEVNCLSFNPYSEFILATGSADK-TVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEP-WV-ICSVSEDNIMQV 401

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Planmine SMEST
Match: SMESG000069623.1 (SMESG000069623.1)

HSP 1 Score: 709.138 bits (1829), Expect = 0.000e+0
Identity = 353/354 (99.72%), Postives = 353/354 (99.72%), Query Frame = 1

Query:  142 MHDXXXXXXXXXXXXXXRKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 1203
            MHDNQSNPQK SSSSQKRKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV
Sbjct:    1 MHDNQSNPQKGSSSSQKRKEIYKYEAPWNIYSINWSIRPDKKFRLAIGSFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDLFATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSALEILRV 354

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Planmine SMEST
Match: SMESG000007931.1 (SMESG000007931.1)

HSP 1 Score: 56.225 bits (134), Expect = 2.450e-8
Identity = 51/222 (22.97%), Postives = 97/222 (43.69%), Query Frame = 1

Query:  550 SFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPI---LAYTAAGEINQI---QWSSLQPDWI-SICYTSALEI 1194
               WN  +  +L +S++D T  +W +          +V  N  +Q + H+  V D+ + K      +F SVG D ++ ++D R  E    +    +   ++ L +N      LAT + +   I + D+R     +  L  H G +  + W+ H    L SG  D +  +WD+     + E      LA+  AG  +++    W+  +P  + S+ Y + L++
Sbjct:  177 GLSWNIKNAGVLLSSAVDGTIQLWDVNCTPENKNDFKVL-NSLSQYLGHEGSVEDVCWHKFS--DQLFGSVGVDKNLLIWDRR--ESKPAVKVMAHSDDVVTLDFNPFSEYILATGSEDKT-IGLWDLRNMGGSLKYLRGHEGSIGQLQWSLHKETILASGGSDNKVHLWDLKKTGTSKEKNYSEELAFIHAGHCSRVIDFAWNGNEPLMMASVSYDNILQL 392

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Planmine SMEST
Match: SMESG000062893.1 (SMESG000062893.1)

HSP 1 Score: 55.4546 bits (132), Expect = 3.775e-8
Identity = 55/227 (24.23%), Postives = 99/227 (43.61%), Query Frame = 1

Query:  559 WNEIDPNILGTSSIDTTCTIWSLET-GQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYE-DPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIED-------PILAYTAAG---EINQIQWSSLQPDWISICYTSALEILRV 1203
            WN I    + ++S D T  +W   T G        +  N   Q I H+  V D+A+    G  D+F SV  D  + ++D+R    S  + E D + + +  +A+N  + + + T + +   + + DMR     +     H+  +  V W+PH+     S   D +  IWD + +    ++       P L +   G   +I+   W+  +P W +IC  +   IL+V
Sbjct:  188 WNPIKAGYILSASDDKTICMWDTNTAGNSSSEGPYI--NPLMQFIGHNTVVEDVAWHLRHG--DVFGSVADDKKLMIWDIRSDNTSKPVIEVDAHTAEVNCIAFNPFNQHLVVTGSADK-TVAMWDMRNLQLKLHSFEAHQDEIFQVQWSPHNETIFASSGTDRRLHIWDCSKIGLEQQEVEFVDGPPELLFIHPGHTAKISDFSWNQFEP-W-TICSVAEDNILQV 407

[Close]

BLAST of DDB1- and CUL4-associated factor 7 vs. Planmine SMEST
Match: SMESG000007931.1 (SMESG000007931.1)

HSP 1 Score: 50.8322 bits (120), Expect = 1.147e-6
Identity = 50/222 (22.52%), Postives = 91/222 (40.99%), Query Frame = 1

Query:  550 SFDWNEIDPNILGTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAGGGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANYLATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGAEDCQALIWDITNMPRAIEDPI---LAYTAAGEINQI---QWSSLQPDWI-SICYTSALEI 1194
               WN  +  +L +S++D T  +W +          +V  N  +Q + H+  V D+ + K      +F SVG D ++ ++D RH           N  +   LA   +D             I + D+R     +  L  H G +  + W+ H    L SG  D +  +WD+     + E      LA+  AG  +++    W+  +P  + S+ Y + L++
Sbjct:  177 GLSWNIKNAGVLLSSAVDGTIQLWDVNCTPENKNDFKVL-NSLSQYLGHEGSVEDVCWHKFS--DQLFGSVGVDKNLLIWD-RHF----------NPFSEYILATGSEDKT-----------IGLWDLRNMGGSLKYLRGHEGSIGQLQWSLHKETILASGGSDNKVHLWDLKKTGTSKEKNYSEELAFIHAGHCSRVIDFAWNGNEPLMMASVSYDNILQL 373

The following BLAST results are available for this feature:

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Human
BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Celegans
BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Fly
BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Zebrafish
BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Xenopus
BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Mouse
BLAST of DDB1- and CUL4-associated factor 7 vs. UniProt/SwissProt
BLAST of DDB1- and CUL4-associated factor 7 vs. TrEMBL
BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Cavefish
BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Sea Lamprey
BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Yeast
BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Nematostella
BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Medaka
BLAST of DDB1- and CUL4-associated factor 7 vs. Planmine SMEST

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DCAF7	0.000e+0	75.96	DDB1 and CUL4 associated factor 7 [Source:HGNC Sym...	[more]
DCAF7	0.000e+0	75.96	DDB1 and CUL4 associated factor 7 [Source:HGNC Sym...	[more]
DCAF7	4.749e-110	62.60	DDB1 and CUL4 associated factor 7 [Source:HGNC Sym...	[more]
DCAF7	3.084e-51	76.29	DDB1 and CUL4 associated factor 7 [Source:HGNC Sym...	[more]
WDR59	6.681e-6	25.56	WD repeat domain 59 [Source:HGNC Symbol;Acc:HGNC:2...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
swan-2	4.473e-160	61.70	Seven WD repeats, AN11 family [Source:UniProtKB/T...	[more]
swan-2	4.473e-160	61.70	Seven WD repeats, AN11 family [Source:UniProtKB/T...	[more]
swan-1	1.082e-123	50.44	Seven WD repeats, AN11 family [Source:UniProtKB/T...	[more]
swan-1	1.082e-123	50.44	Seven WD repeats, AN11 family [Source:UniProtKB/T...	[more]
lin-53	4.521e-9	24.14	Probable histone-binding protein lin-53 [Source:U...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
wap	0.000e+0	77.51	gene:FBgn0266848 transcript:FBtr0305147	[more]
wap	0.000e+0	77.51	gene:FBgn0266848 transcript:FBtr0309240	[more]
wap	0.000e+0	77.51	gene:FBgn0266848 transcript:FBtr0339498	[more]
wap	0.000e+0	77.51	gene:FBgn0266848 transcript:FBtr0077368	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dcaf7	0.000e+0	76.85	ddb1 and cul4 associated factor 7 [Source:ZFIN;Acc...	[more]
daw1	2.699e-7	23.53	dynein assembly factor with WDR repeat domains 1 [...	[more]
daw1	3.020e-7	23.53	dynein assembly factor with WDR repeat domains 1 [...	[more]
grwd1	1.289e-6	22.51	glutamate-rich WD repeat containing 1 [Source:ZFIN...	[more]
grwd1	1.289e-6	22.51	glutamate-rich WD repeat containing 1 [Source:ZFIN...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
dcaf7	0.000e+0	76.26	DDB1 and CUL4 associated factor 7 [Source:NCBI gen...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Dcaf7	0.000e+0	75.96	DDB1 and CUL4 associated factor 7 [Source:MGI Symb...	[more]
Wdr59	4.725e-6	25.56	WD repeat domain 59 [Source:MGI Symbol;Acc:MGI:244...	[more]
Wdr59	5.265e-6	25.90	WD repeat domain 59 [Source:MGI Symbol;Acc:MGI:244...	[more]
Wdr59	5.713e-6	25.90	WD repeat domain 59 [Source:MGI Symbol;Acc:MGI:244...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P61963\|DCAF7_MOUSE	0.000e+0	75.96	DDB1- and CUL4-associated factor 7 OS=Mus musculus...	[more]
sp\|P61962\|DCAF7_HUMAN	0.000e+0	75.96	DDB1- and CUL4-associated factor 7 OS=Homo sapiens...	[more]
sp\|Q552R1\|DCAF7_DICDI	3.314e-143	58.58	DDB1- and CUL4-associated factor 7 homolog OS=Dict...	[more]
sp\|Q9LPV9\|LWD1_ARATH	7.654e-132	54.94	WD repeat-containing protein LWD1 OS=Arabidopsis t...	[more]
sp\|Q38960\|LWD2_ARATH	3.390e-130	55.23	WD repeat-containing protein LWD2 OS=Arabidopsis t...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A210Q3D8	0.000e+0	79.53	DDB1-and CUL4-associated factor 7 OS=Mizuhopecten ...	[more]
K1QTB8	0.000e+0	79.23	WD repeat-containing protein 68 OS=Crassostrea gig...	[more]
A0A1S3JL82	0.000e+0	79.82	DDB1- and CUL4-associated factor 7 isoform X1 OS=L...	[more]
A0A023GJ78	0.000e+0	78.89	Putative ddb1-and cul4-associated factor 7 (Fragme...	[more]
A0A2T7PIZ7	0.000e+0	78.93	WD_REPEATS_REGION domain-containing protein OS=Pom...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
dcaf7	0.000e+0	77.15	DDB1 and CUL4 associated factor 7 [Source:NCBI gen...	[more]
sec31b	1.607e-6	25.54	protein transport protein Sec31A-like [Source:NCBI...	[more]
rbbp4	6.047e-6	24.14	RB binding protein 4, chromatin remodeling factor ...	[more]
pex7	7.442e-6	23.76	peroxisomal biogenesis factor 7 [Source:NCBI gene;...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
DCAF7	2.408e-175	76.43	DDB1 and CUL4 associated factor 7 [Source:HGNC Sym...	[more]
ENSPMAT00000008002.1	4.840e-7	22.28	pep scaffold:Pmarinus_7.0:GL477852:421:9512:1 gene...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
YPL247C_mRNA	2.525e-55	37.35	Putative protein of unknown function; green fluore...	[more]
MTC5	1.004e-6	27.34	Subunit of SEACAT, a subcomplex of the SEA complex...	[more]
RRB1	1.674e-6	23.13	Specific chaperone for ribosomal protein Rpl3p; bi...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO44974	0.000e+0	76.92	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
DCAF7	0.000e+0	76.85	DDB1 and CUL4 associated factor 7 [Source:NCBI gen...	[more]
rbb4l	2.329e-6	24.45	histone-binding protein RBBP7 [Source:NCBI gene;Ac...	[more]
rbbp4	5.553e-6	24.45	RB binding protein 4, chromatin remodeling factor ...	[more]

BLAST of DDB1- and CUL4-associated factor 7 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4


Match Name	E-value	Identity	Description
SMESG000069623.1	0.000e+0	99.72	SMESG000069623.1	[more]
SMESG000007931.1	2.450e-8	22.97	SMESG000007931.1	[more]
SMESG000062893.1	3.775e-8	24.23	SMESG000062893.1	[more]
SMESG000007931.1	1.147e-6	22.52	SMESG000007931.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30022821 ID=SMED30022821|Name=DDB1- and CUL4-associated factor 7|organism=Schmidtea mediterranea sexual|type=transcript|length=1322bp
TTGTGTGTTTTAATATATAAATTAAATGCATATAAAACAAATGTCCATTT
AATGAAAATAAATAAATTCAATAGTTAAATATTGTTTTCAATATTAATTT
TTATCATTTTTTATCATTTTTAATAATCTATTCTGATGGCTATGCATGAT
AATCAATCAAATCCTCAAAAAAGTTCCAGCAGTTCTCAGAAACGAAAGGA
AATTTATAAATACGAAGCACCATGGAATATATACAGCATTAACTGGTCAA
TCAGACCAGATAAAAAATTTAGATTAGCTATTGGAAGTTTTATAGAAGAA
TATAATAATAAAGTTCAAATAATTTCGTTGGATGAAGATAAGGGCGAATT
CGTAGCAGTTTCTTGTGTCGACCATTTATATCCAACCACAAAAATTATGT
GGATTCCAGACCCCAAAGGTCATTTACCGGATTTATTTGCTACCAGTGGT
GACTATTTGCGAATTTGGCGGGTACCAGCAAATAACGAAACGCATTTGGA
ATGTCTCCTAAACAGTAATAAAAATTCCGATTTCTGTGCACCTTTGACTT
CATTTGACTGGAACGAAATAGACCCTAATATTTTGGGAACTTCCAGCATT
GATACGACTTGTACGATATGGAGTTTAGAGACGGGACAAGTAATGGGTCG
CACAACTCAAGTGACTGGTAATGTAAAAACCCAGTTAATAGCTCACGATA
AAGAAGTTTACGATATTGCATTTACTAAAGCTGGCGGTGGGCGAGACATA
TTCGCTAGTGTTGGAGCTGATGCGTCTGTACGAATGTTTGATTTACGTCA
TTTGGAGCATTCTACTATTATTTACGAAGATCCAAATAAATCAGCCCTTT
TGCGATTGGCTTGGAATAAACAAGACGCGAATTACCTTGCGACGTTCACC
TTAAATTCACCAGAAATAATCGTGCTAGATATGCGAGTTCCATGCACTCC
GGTGGCTCGCCTAAACAATCACCGAGGTTGTGTTAATGGAGTGGCTTGGG
CCCCTCATTCCAGTTGCCATTTGTGCAGTGGGGCAGAAGACTGTCAAGCA
CTTATTTGGGACATAACAAACATGCCTCGAGCTATAGAGGACCCAATATT
AGCATATACTGCTGCTGGGGAAATCAATCAAATCCAGTGGAGCTCCTTGC
AGCCCGATTGGATTTCAATCTGTTACACGAGTGCTTTAGAAATATTACGG
GTTTAATTCAGTGTTTGCTTGATATTTTCATGTGTAGTGATGAATCATTT
TGAGGTTTTTTCACGTTTTTCAATATATGTATTTGTCGGTTATTCTCAAA
TTATTATTATTTTATTTTTACA

protein sequence of SMED30022821-orf-1

>SMED30022821-orf-1 ID=SMED30022821-orf-1|Name=SMED30022821-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=357bp
MAMHDNQSNPQKSSSSSQKRKEIYKYEAPWNIYSINWSIRPDKKFRLAIG
SFIEEYNNKVQIISLDEDKGEFVAVSCVDHLYPTTKIMWIPDPKGHLPDL
FATSGDYLRIWRVPANNETHLECLLNSNKNSDFCAPLTSFDWNEIDPNIL
GTSSIDTTCTIWSLETGQVMGRTTQVTGNVKTQLIAHDKEVYDIAFTKAG
GGRDIFASVGADASVRMFDLRHLEHSTIIYEDPNKSALLRLAWNKQDANY
LATFTLNSPEIIVLDMRVPCTPVARLNNHRGCVNGVAWAPHSSCHLCSGA
EDCQALIWDITNMPRAIEDPILAYTAAGEINQIQWSSLQPDWISICYTSA
LEILRV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0048703	embryonic viscerocranium morphogenesis
GO:0051216	cartilage development
GO:0007275	multicellular organism development
GO:0016567	protein ubiquitination

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036322	WD40_repeat_dom_sf
IPR001680	WD40_repeat
IPR015943	WD40/YVTN_repeat-like_dom_sf
IPR019775	WD40_repeat_CS
IPR017986	WD40_repeat_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016363	nuclear matrix
GO:0016604	nuclear body
GO:0043234	protein complex
GO:0080008	Cul4-RING E3 ubiquitin ligase complex

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001680	WD40 repeat	SMART	SM00320	WD40_4	coord: 120..163 e-value: 5.7 score: 12.3 coord: 269..309 e-value: 1.8E-6 score: 37.5 coord: 177..219 e-value: 0.0023 score: 27.2
IPR001680	WD40 repeat	PROSITE	PS50082	WD_REPEATS_2	coord: 276..318 score: 9.874
IPR015943	WD40/YVTN repeat-like-containing domain superfamily	GENE3D	G3DSA:2.130.10.10		coord: 21..356 e-value: 1.4E-37 score: 131.7
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..17
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..20
None	No IPR available	PANTHER	PTHR19919	WD REPEAT CONTAINING PROTEIN	coord: 14..356
IPR019775	WD40 repeat, conserved site	PROSITE	PS00678	WD_REPEATS_1	coord: 296..310
IPR017986	WD40-repeat-containing domain	PROSITE	PS50294	WD_REPEATS_REGION	coord: 130..318 score: 10.021
IPR036322	WD40-repeat-containing domain superfamily	SUPERFAMILY	SSF50978	WD40 repeat-like	coord: 31..312