phosphatidylinositide phosphatase SAC2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30022796 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Human
Match: INPP5F (inositol polyphosphate-5-phosphatase F [Source:HGNC Symbol;Acc:HGNC:17054]) HSP 1 Score: 449.899 bits (1156), Expect = 3.299e-140 Identity = 302/762 (39.63%), Postives = 455/762 (59.71%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKT----NEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ G AL+C R G + A ++ WNP+CLG ++G IGKI+ +D L+LI + VG+ P V +++KI +SL+ + +L+++LCK+HHFGI K ++I D K L+K F NV S P K+ +++E+ ERR+LEE KMF ++E+ FY + D+T+++QRQ + + PLW++ D+RFFWNK+M+Q+ E I ++ +IP+IQGFVQI+ +N S P P +D H +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V N H +SFVQ RGSVPVFWSQ +Y+P L+RSE+E F HFE +LN Y+K V++NLVD E+ I DAYL+ ++ FN+ +T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP +I Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L K+ + + +EL +Q ++ +K +E+ G LI C+ + + +D++ + L++ Y+V+ D + + L L++++KI+IG E +F + + + +R++Y
Sbjct: 1 MELFQAKDHYILQQGERALWCSRRDGGLQLRPATDLLLAWNPICLGLVEGVIGKIQLHSDLPWWLILIRQKALVGKLPGDHEVCKVTKIAVLSLSEMEPQDLELELCKKHHFGINKPEKIIPSPDDSKFLLKTFTHIKSNV----------SAP-NKKKVKESKEKEKLERRLLEELLKMFMDSES---FYYSL----TYDLTNSVQRQSTGERDGR-PLWQKVDDRFFWNKYMIQDLTE------------------------------IGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHP-RFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHN----HTLSFVQTRGSVPVFWSQVGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQ--AGREKIIGDAYLKQVLLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHKENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLS-NSAYYVAYY--------DDEVDKVNQYQRLSLENLEKIEIGPEPTLFGKPKFSCMRLHY 696
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Human
Match: INPP5F (inositol polyphosphate-5-phosphatase F [Source:HGNC Symbol;Acc:HGNC:17054]) HSP 1 Score: 451.825 bits (1161), Expect = 9.614e-137 Identity = 302/762 (39.63%), Postives = 455/762 (59.71%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLK----TNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ G AL+C R G + A ++ WNP+CLG ++G IGKI+ +D L+LI + VG+ P V +++KI +SL+ + +L+++LCK+HHFGI K ++I D K L+K F NV S P K+ +++E+ ERR+LEE KMF ++E+ FY + D+T+++QRQ + + PLW++ D+RFFWNK+M+Q+ E I ++ +IP+IQGFVQI+ +N S P P +D H +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V N H +SFVQ RGSVPVFWSQ +Y+P L+RSE+E F HFE +LN Y+K V++NLVD E+ I DAYL+ ++ FN+ +T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP +I Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L K+ + + +EL +Q ++ +K +E+ G LI C+ + + +D++ + L++ Y+V+ D + + L L++++KI+IG E +F + + + +R++Y
Sbjct: 1 MELFQAKDHYILQQGERALWCSRRDGGLQLRPATDLLLAWNPICLGLVEGVIGKIQLHSDLPWWLILIRQKALVGKLPGDHEVCKVTKIAVLSLSEMEPQDLELELCKKHHFGINKPEKIIPSPDDSKFLLKTFTHIKSNV----------SAP-NKKKVKESKEKEKLERRLLEELLKMFMDSES---FYYSL----TYDLTNSVQRQSTGERD-GRPLWQKVDDRFFWNKYMIQDLTE------------------------------IGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHP-RFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHN----HTLSFVQTRGSVPVFWSQVGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQ--AGREKIIGDAYLKQVLLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHKENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLS-NSAYYVA--------YYDDEVDKVNQYQRLSLENLEKIEIGPEPTLFGKPKFSCMRLHY 696
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Human
Match: INPP5F (inositol polyphosphate-5-phosphatase F [Source:HGNC Symbol;Acc:HGNC:17054]) HSP 1 Score: 376.326 bits (965), Expect = 2.157e-114 Identity = 264/662 (39.88%), Postives = 397/662 (59.97%), Query Frame = 1
Query: 352 NLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLK----TNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
+L+++LCK+HHFGI K ++I D K L+K F NV S P K+ +++E+ ERR+LEE KMF ++E+ FY + D+T+++QRQ + + PLW++ D+RFFWNK+M+Q+ E I ++ +IP+IQGFVQI+ +N S P P +D H +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V N H +SFVQ RGSVPVFWSQ +Y+P L+RSE+E F HFE +LN Y+K V++NLVD E+ I DAYL+ ++ FN+ +T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP +I Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L K+ + + +EL +Q ++ +K +E+ G LI C+ + + +D++ + L++ Y+V+ D + + L L++++KI+IG E +F + + + +R++Y
Sbjct: 5 DLELELCKKHHFGINKPEKIIPSPDDSKFLLKTFTHIKSNV----------SAP-NKKKVKESKEKEKLERRLLEELLKMFMDSES---FYYSL----TYDLTNSVQRQSTGERDGR-PLWQKVDDRFFWNKYMIQDLTE------------------------------IGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHP-RFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHN----HTLSFVQTRGSVPVFWSQVGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQ--AGREKIIGDAYLKQVLLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHKENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLS-NSAYYVA--------YYDDEVDKVNQYQRLSLENLEKIEIGPEPTLFGKPKFSCMRLHY 600
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Human
Match: INPP5F (inositol polyphosphate-5-phosphatase F [Source:HGNC Symbol;Acc:HGNC:17054]) HSP 1 Score: 377.867 bits (969), Expect = 6.677e-111 Identity = 264/662 (39.88%), Postives = 397/662 (59.97%), Query Frame = 1
Query: 352 NLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLK----TNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
+L+++LCK+HHFGI K ++I D K L+K F NV S P K+ +++E+ ERR+LEE KMF ++E+ FY + D+T+++QRQ + + PLW++ D+RFFWNK+M+Q+ E I ++ +IP+IQGFVQI+ +N S P P +D H +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V N H +SFVQ RGSVPVFWSQ +Y+P L+RSE+E F HFE +LN Y+K V++NLVD E+ I DAYL+ ++ FN+ +T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP +I Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L K+ + + +EL +Q ++ +K +E+ G LI C+ + + +D++ + L++ Y+V+ D + + L L++++KI+IG E +F + + + +R++Y
Sbjct: 5 DLELELCKKHHFGINKPEKIIPSPDDSKFLLKTFTHIKSNV----------SAP-NKKKVKESKEKEKLERRLLEELLKMFMDSES---FYYSL----TYDLTNSVQRQSTGERD-GRPLWQKVDDRFFWNKYMIQDLTE------------------------------IGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHP-RFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHN----HTLSFVQTRGSVPVFWSQVGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQ--AGREKIIGDAYLKQVLLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHKENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLS-NSAYYVA--------YYDDEVDKVNQYQRLSLENLEKIEIGPEPTLFGKPKFSCMRLHY 600
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Human
Match: INPP5F (inositol polyphosphate-5-phosphatase F [Source:HGNC Symbol;Acc:HGNC:17054]) HSP 1 Score: 377.867 bits (969), Expect = 6.677e-111 Identity = 264/662 (39.88%), Postives = 397/662 (59.97%), Query Frame = 1
Query: 352 NLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLK----TNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
+L+++LCK+HHFGI K ++I D K L+K F NV S P K+ +++E+ ERR+LEE KMF ++E+ FY + D+T+++QRQ + + PLW++ D+RFFWNK+M+Q+ E I ++ +IP+IQGFVQI+ +N S P P +D H +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V N H +SFVQ RGSVPVFWSQ +Y+P L+RSE+E F HFE +LN Y+K V++NLVD E+ I DAYL+ ++ FN+ +T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP +I Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L K+ + + +EL +Q ++ +K +E+ G LI C+ + + +D++ + L++ Y+V+ D + + L L++++KI+IG E +F + + + +R++Y
Sbjct: 5 DLELELCKKHHFGINKPEKIIPSPDDSKFLLKTFTHIKSNV----------SAP-NKKKVKESKEKEKLERRLLEELLKMFMDSES---FYYSL----TYDLTNSVQRQSTGERD-GRPLWQKVDDRFFWNKYMIQDLTE------------------------------IGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHP-RFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHN----HTLSFVQTRGSVPVFWSQVGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQ--AGREKIIGDAYLKQVLLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHKENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLS-NSAYYVA--------YYDDEVDKVNQYQRLSLENLEKIEIGPEPTLFGKPKFSCMRLHY 600
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Celegans
Match: W09C5.7 (pep chromosome:WBcel235:I:13654009:13658167:1 gene:WBGene00012353.1 transcript:W09C5.7a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:W09C5.7) HSP 1 Score: 239.965 bits (611), Expect = 7.645e-66 Identity = 158/444 (35.59%), Postives = 238/444 (53.60%), Query Frame = 1
Query: 586 KMFQENENGDCFYLCYDSEKSCDITSNIQR--QKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEK-VVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICE-QKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIG 1902
K+F ++++ FY C +S D+T + Q+ +K+ + S ++ FFWNK M+ E+ + ++ PI+QG+V ++ D + Y + + +ISRR+ RAG R+ RRG+DE NVAN+VETE L + H +SFVQ RGS+PVFWSQ KY PP+I+ RS EE F +HF+ +Y+ +V V+LVD E +A +L+H +K + +T FD H +CRGL F + LI + + + + + WVDK G + + QK + R NC+DCLDRTN+VQ ++ V+ Q ++LG+ P P Q MQ+MWA+NGD +S QY+GTAA+KGD TR G R + G++KDG +S SRYYL ++ RQ AI+++ G
Sbjct: 147 KLFNDSKD---FYFC----RSRDVTISSQKYFEKREAHTS--------EDSFFWNKRMVGNLGEA--------------------------------KISDKFTCPIMQGYVATSQLEIT-----------------DQINAY-LTITIISRRSTRRAGARYLRRGIDEASNVANFVETELILNIFE----HELSFVQCRGSIPVFWSQRGFKYRPPLIINRSVEETHGVFTEHFKRLKAHYDTPLVAVSLVDQR--GRELPLAQRFLEHCVKADDNDVTFFSFDLHQHCRGLNFQKLQTLISSMEETLKTIGFCWVDKTGEVVQSQKGVVRTNCIDCLDRTNLVQGQISLFVVLQQAQRLGIFGPLCEPPEVLVQTMQTMWADNGDVISTQYAGTAALKGDVTRNGERKLMGVMKDGYNSASRYYLTHTKDAQRQKAINIVTG 519
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Celegans
Match: sac-1 (SAC1 PIP phosphatase (Yeast Suppressor of ACtin) homolog [Source:UniProtKB/TrEMBL;Acc:Q93641]) HSP 1 Score: 176.022 bits (445), Expect = 7.135e-46 Identity = 151/451 (33.48%), Postives = 229/451 (50.78%), Query Frame = 1
Query: 658 TSNIQRQKQSQYNSNNPLWR------RADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVEN-DKSPHLVSFVQIRGSVPVFWSQF-SLKYHPPIILERSEEENQEAFKKHFEAELNNYE-KVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICE--QKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXX--NFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGN---ESSVEIINLRSGRNDTEQ 1959
T +I R Q + PL++ RA ERF WN H+L + + + E +P+I GF+ + VN+ + E+ + +ISRR+ RAG RF +RGVD +G+ AN+VETEQ ++ N DK HL SFVQ+RGS+P+ W+Q +L++ P L+ ++++ AF + F +Y K V+VNLV N + E+K+ + + N + FDFH C +Q+ + +L + +++ Y ++ N + Q+ FR NC+DCLDRTNVVQ MLA + QLR LG+L E+ + + MWA+NGD SRQY+GT A+K DFTR G RT G +KDG++++SRY + RQ +IDL +GN +SS ++L S T+Q
Sbjct: 148 TLDISRTFQWLQENAVPLFKTRSMLDRASERFIWNGHLLSQIRQ--------------------------------VPGAERYTLPVIHGFI----------GQNRVNV-----------NGKEIKLTIISRRSIYRAGVRFYKRGVDVDGHAANFVETEQIVEYTNPDK--HLTSFVQLRGSIPLLWTQKPNLRWQPMPTLKPTDDQ-LAAFNRAFSWHKQHYGGKHVIVNLV--NQKGREKKVGGELERISRQANIEFVRYHQFDFHKECHSMQWHRIDLLREQLSQEISSFGYFYLSPNSMETSRFQRGFFRTNCMDCLDRTNVVQSMLARESLTEQLRMLGILYSEQKVQDIPLLEDAFKQMWADNGDECSRQYAGTGALKADFTRHGRRTYVGAMKDGVNAVSRYVRNNFGDGYRQDSIDLFLGNFLVDSSDLPVSLESSILSTDQ 540
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Celegans
Match: W09C5.7 (pep chromosome:WBcel235:I:13656201:13658163:1 gene:WBGene00012353.1 transcript:W09C5.7b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:W09C5.7) HSP 1 Score: 130.568 bits (327), Expect = 4.884e-32 Identity = 63/136 (46.32%), Postives = 91/136 (66.91%), Query Frame = 1
Query: 1501 FRDMKYSWVDKNGLICE-QKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIG 1902
+ + + WVDK G + + QK + R NC+DCLDRTN+VQ ++ V+ Q ++LG+ P P Q MQ+MWA+NGD +S QY+GTAA+KGD TR G R + G++KDG +S SRYYL ++ RQ AI+++ G
Sbjct: 5 LKTIGFCWVDKTGEVVQSQKGVVRTNCIDCLDRTNLVQGQISLFVVLQQAQRLGIFGPLCEPPEVLVQTMQTMWADNGDVISTQYAGTAALKGDVTRNGERKLMGVMKDGYNSASRYYLTHTKDAQRQKAINIVTG 140
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Celegans
Match: unc-26 (Synaptojanin [Source:UniProtKB/Swiss-Prot;Acc:G5ECL2]) HSP 1 Score: 112.464 bits (280), Expect = 2.273e-25 Identity = 75/252 (29.76%), Postives = 127/252 (50.40%), Query Frame = 1
Query: 1090 GNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAY-LQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKG-----DFTRTGARTMNGLVKDG 1827
GNVAN+VETEQ L + + S +QIRGS+P+FW Q + + R+ E + A+ +H + Y + +VNL+ + ER + DA+ QH +P + + FD+H + + + + L K ++ + + ++ Q + R NC+DCLDRTN VQ + + Q+ L L + + ++ +I++ +W NGD S Y+GT A+ G D +R+ ART+ + DG
Sbjct: 222 GNVANFVETEQLLLFDEKE----CSLLQIRGSIPLFWEQPGVNVGSHKVKLRAFETSLPAYHRHLSQLQHRYGEFAIVNLLGR--KEGERVLGDAFKTQHKSSHFAPLVDFIDFDYHAQMK-ISKEAIVQLKKKMSPHMTKHGFFYSMGKEIVKRQTGVIRTNCLDCLDRTNAVQTAIGLQMSHDQVAFLNLNAGKVNVEQRVEEILRDLWQKNGDQCSTIYAGTGALDGKSKLKDASRSLARTIQNNLMDG 466
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Celegans
Match: unc-26 (Synaptojanin [Source:UniProtKB/Swiss-Prot;Acc:G5ECL2]) HSP 1 Score: 112.464 bits (280), Expect = 2.273e-25 Identity = 75/252 (29.76%), Postives = 127/252 (50.40%), Query Frame = 1
Query: 1090 GNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAY-LQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKG-----DFTRTGARTMNGLVKDG 1827
GNVAN+VETEQ L + + S +QIRGS+P+FW Q + + R+ E + A+ +H + Y + +VNL+ + ER + DA+ QH +P + + FD+H + + + + L K ++ + + ++ Q + R NC+DCLDRTN VQ + + Q+ L L + + ++ +I++ +W NGD S Y+GT A+ G D +R+ ART+ + DG
Sbjct: 222 GNVANFVETEQLLLFDEKE----CSLLQIRGSIPLFWEQPGVNVGSHKVKLRAFETSLPAYHRHLSQLQHRYGEFAIVNLLGR--KEGERVLGDAFKTQHKSSHFAPLVDFIDFDYHAQMK-ISKEAIVQLKKKMSPHMTKHGFFYSMGKEIVKRQTGVIRTNCLDCLDRTNAVQTAIGLQMSHDQVAFLNLNAGKVNVEQRVEEILRDLWQKNGDQCSTIYAGTGALDGKSKLKDASRSLARTIQNNLMDG 466
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Fly
Match: CG7956 (gene:FBgn0038890 transcript:FBtr0334664) HSP 1 Score: 359.762 bits (922), Expect = 3.105e-105 Identity = 276/852 (32.39%), Postives = 422/852 (49.53%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKT--DRITTPTDGQKSL-----------------------MKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQ--DMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGY--ELNIFRLRQNM---IRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAA 2508
ME+F+T HYI + +L+ R + S ++S + C+G G +G I E L+++ VG + + KI +I + + + D+ C +H + T ++T + S+ +K +KN + + K + + +R+ ERR+ EE K+F E D FY +D CDIT+N+QR + S + + DERFFWNKHM+++ I D KT+ ++PIIQGF+Q++ N + N + L+SRR+R+RAGTR++RRGVDE GN ANYVETEQ L + H +SF Q+RGSVP++WSQ KY PP L+R E Q+AF+ HF EL Y +V +VNLV+ + + E+ I DAY H+IK N+ ++ V FDFHDYCRG++F+NVS LI V M + W D+ G+IC QKS+FRVNC+DCLDRTNVVQ + V+E+QL KLGL P +P +WANNGD +SRQY+GT A+KGD+TRTG R ++G++KDGM+S +RYYL R ++ RQA IDL++GN+ S E ++ G+ ++ + + K L C++ L T + +G LI + + + +++T+ L+T + Y V+ S + F+ + L ++ I++G + IF+ +R+ Y + +E F F+ +LR FNN+ +K + ES+ +I E F A
Sbjct: 1 MEVFQTDSHYIFVKRDKSLWWHRRTSEFSIKAGWDLSSVDDIECIGVTHGIVGVISLPNVYEPHLVVVKEASAVG---VLYPPHLVYKIKSICILSADDPDTDLPNCTKHTKSNQSTPTHSVSTSNNNNASVPSSGGGSSKSTKLFEGMNKTWGAVKSAGNTIKNTTQQAANLATKQ----VKSSVGIREPRHIERRITEELHKIFDET---DSFYFSFD----CDITNNLQRHEAKSEESQS----QPDERFFWNKHMIRDLINLND----KTW-----------------------------ILPIIQGFMQVE------------NCVIGNEC---------FTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQILSFRH----HQLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAETQQAFELHFTKELETYGRVCIVNLVEQSGK--EKTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGMRFENVSALIDAVGPEAGAMGFHWRDQRGMICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQLVKLGLSPPYTPIPEQLKSPFMVLWANNGDIISRQYAGTNALKGDYTRTGERKISGMMKDGMNSANRYYLARFKDSYRQATIDLMLGNQVSSESLSALGGQAGPDENDGTENAEQAKLLVEDCRRLLLGTAQYPVGAWGLIDADPSSGDINETEVDTILLLT-DDCYIVAEYDSHLDKIVRFE--------KVQLTQVRLIELGMHQQTKIFQGSAPAHLCLRLNYSV-----------------------DEQEGYFHMFRSANLRFFNNMAYVIKTQEEVAESMTSIVEMFRIA 742
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Fly
Match: CG7956 (gene:FBgn0038890 transcript:FBtr0084112) HSP 1 Score: 359.377 bits (921), Expect = 5.793e-105 Identity = 276/852 (32.39%), Postives = 422/852 (49.53%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKT--DRITTPTDGQKSL-----------------------MKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQ--DMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGY--ELNIFRLRQNM---IRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAA 2508
ME+F+T HYI + +L+ R + S ++S + C+G G +G I E L+++ VG + + KI +I + + + D+ C +H + T ++T + S+ +K +KN + + K + + +R+ ERR+ EE K+F E D FY +D CDIT+N+QR + S + + DERFFWNKHM+++ I D KT+ ++PIIQGF+Q++ N + N + L+SRR+R+RAGTR++RRGVDE GN ANYVETEQ L + H +SF Q+RGSVP++WSQ KY PP L+R E Q+AF+ HF EL Y +V +VNLV+ + + E+ I DAY H+IK N+ ++ V FDFHDYCRG++F+NVS LI V M + W D+ G+IC QKS+FRVNC+DCLDRTNVVQ + V+E+QL KLGL P +P +WANNGD +SRQY+GT A+KGD+TRTG R ++G++KDGM+S +RYYL R ++ RQA IDL++GN+ S E ++ G+ ++ + + K L C++ L T + +G LI + + + +++T+ L+T + Y V+ S + F+ + L ++ I++G + IF+ +R+ Y + +E F F+ +LR FNN+ +K + ES+ +I E F A
Sbjct: 1 MEVFQTDSHYIFVKRDKSLWWHRRTSEFSIKAGWDLSSVDDIECIGVTHGIVGVISLPNVYEPHLVVVKEASAVG---VLYPPHLVYKIKSICILSADDPDTDLPNCTKHTKSNQSTPTHSVSTSNNNNASVPSSGGGSSKSTKLFEGMNKTWGAVKSAGNTIKNTTQQAANLATKQ----VKSSVGIREPRHIERRITEELHKIFDET---DSFYFSFD----CDITNNLQRHEAKSEESQS----QPDERFFWNKHMIRDLINLND----KTW-----------------------------ILPIIQGFMQVE------------NCVIGNEC---------FTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQILSFRH----HQLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAETQQAFELHFTKELETYGRVCIVNLVEQSGK--EKTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGMRFENVSALIDAVGPEAGAMGFHWRDQRGMICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQLVKLGLSPPYTPIPEQLKSPFMVLWANNGDIISRQYAGTNALKGDYTRTGERKISGMMKDGMNSANRYYLARFKDSYRQATIDLMLGNQVSSESLSALGGQAGPDENDGTENAEQAKLLVEDCRRLLLGTAQYPVGAWGLIDADPSSGDINETEVDTILLLT-DDCYIVAEYDSHLDKIVRFE--------KVQLTQVRLIELGMHQQTKIFQGSAPAHLCLRLNYSV-----------------------DEQEGYFHMFRSANLRFFNNMAYVIKTQEEVAESMTSIVEMFRIA 742
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Fly
Match: CG7956 (gene:FBgn0038890 transcript:FBtr0301211) HSP 1 Score: 360.533 bits (924), Expect = 8.324e-105 Identity = 276/852 (32.39%), Postives = 422/852 (49.53%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKT--DRITTPTDGQKSL-----------------------MKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQ--DMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGY--ELNIFRLRQNM---IRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAA 2508
ME+F+T HYI + +L+ R + S ++S + C+G G +G I E L+++ VG + + KI +I + + + D+ C +H + T ++T + S+ +K +KN + + K + + +R+ ERR+ EE K+F E D FY +D CDIT+N+QR + S + + DERFFWNKHM+++ I D KT+ ++PIIQGF+Q++ N + N + L+SRR+R+RAGTR++RRGVDE GN ANYVETEQ L + H +SF Q+RGSVP++WSQ KY PP L+R E Q+AF+ HF EL Y +V +VNLV+ + + E+ I DAY H+IK N+ ++ V FDFHDYCRG++F+NVS LI V M + W D+ G+IC QKS+FRVNC+DCLDRTNVVQ + V+E+QL KLGL P +P +WANNGD +SRQY+GT A+KGD+TRTG R ++G++KDGM+S +RYYL R ++ RQA IDL++GN+ S E ++ G+ ++ + + K L C++ L T + +G LI + + + +++T+ L+T + Y V+ S + F+ + L ++ I++G + IF+ +R+ Y + +E F F+ +LR FNN+ +K + ES+ +I E F A
Sbjct: 1 MEVFQTDSHYIFVKRDKSLWWHRRTSEFSIKAGWDLSSVDDIECIGVTHGIVGVISLPNVYEPHLVVVKEASAVG---VLYPPHLVYKIKSICILSADDPDTDLPNCTKHTKSNQSTPTHSVSTSNNNNASVPSSGGGSSKSTKLFEGMNKTWGAVKSAGNTIKNTTQQAANLATKQ----VKSSVGIREPRHIERRITEELHKIFDET---DSFYFSFD----CDITNNLQRHEAKSEESQS----QPDERFFWNKHMIRDLINLND----KTW-----------------------------ILPIIQGFMQVE------------NCVIGN---------ECFTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQILSFRH----HQLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAETQQAFELHFTKELETYGRVCIVNLVEQSGK--EKTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGMRFENVSALIDAVGPEAGAMGFHWRDQRGMICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQLVKLGLSPPYTPIPEQLKSPFMVLWANNGDIISRQYAGTNALKGDYTRTGERKISGMMKDGMNSANRYYLARFKDSYRQATIDLMLGNQVSSESLSALGGQAGPDENDGTENAEQAKLLVEDCRRLLLGTAQYPVGAWGLIDADPSSGDINETEVDTILLLT-DDCYIVAEYDSHLDKIVRFE--------KVQLTQVRLIELGMHQQTKIFQGSAPAHLCLRLNYSV-----------------------DEQEGYFHMFRSANLRFFNNMAYVIKTQEEVAESMTSIVEMFRIA 742
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Fly
Match: CG7956 (gene:FBgn0038890 transcript:FBtr0301212) HSP 1 Score: 322.398 bits (825), Expect = 3.540e-95 Identity = 231/639 (36.15%), Postives = 332/639 (51.96%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKT--DRITTPTDGQKS-------------LMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXX------XXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLR-LREMSRQAAIDLIIG 1902
ME+F+T HYI + +L+ R + S ++S + C+G G +G I E L+++ VG + + KI +I + + + D+ C +H + T ++T + S L +G + V I ++ K V+ ERR+ EE K+F E D FY +D CDIT+N+QR + S + + DERFFWNKHM+++ I D KT+ ++PIIQGF+Q++ N + N + L+SRR+R+RAGTR++RRGVDE GN ANYVETEQ L + H +SF Q+RGSVP++WSQ KY PP L+R E Q+AF+ HF EL Y +V +VNLV+ + E+ I DAY H+IK N+ ++ V FDFHDYCRG++F+NVS LI V M + W D+ G+IC QKS+FRVNC+DCLDRTNVVQ + V+E+QL KLGL P +P +WANNGD +SRQY+GT A+KGD+TRTG R ++G++KDGM+S +R++++ + RQ IDL+ G
Sbjct: 1 MEVFQTDSHYIFVKRDKSLWWHRRTSEFSIKAGWDLSSVDDIECIGVTHGIVGVISLPNVYEPHLVVVKEASAVG---VLYPPHLVYKIKSICILSADDPDTDLPNCTKHTKSNQSTPTHSVSTSNNNNASVPSSGGGSSKSTKLFEGMNKTWGAVKSAGNTIKNTTQQAANLATKQVKSSVGIREPRHIERRITEELHKIFDET---DSFYFSFD----CDITNNLQRHEAKSEESQS----QPDERFFWNKHMIRDLINLND----KTW-----------------------------ILPIIQGFMQVE------------NCVIGNEC---------FTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQILSFRH----HQLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAETQQAFELHFTKELETYGRVCIVNLVEQS--GKEKTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGMRFENVSALIDAVGPEAGAMGFHWRDQRGMICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQLVKLGLSPPYTPIPEQLKSPFMVLWANNGDIISRQYAGTNALKGDYTRTGERKISGMMKDGMNSANRFFIQNFADSFRQCIIDLMQG 565
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Fly
Match: CG7956 (gene:FBgn0038890 transcript:FBtr0334663) HSP 1 Score: 324.709 bits (831), Expect = 5.884e-92 Identity = 230/643 (35.77%), Postives = 335/643 (52.10%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKT--DRITTPTDGQKSL-----------------------MKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLR-LREMSRQAAIDLIIG 1902
ME+F+T HYI + +L+ R + S ++S + C+G G +G I E L+++ VG + + KI +I + + + D+ C +H + T ++T + S+ +K +KN + + K + + +R+ ERR+ EE K+F E D FY +D CDIT+N+QR + S + + DERFFWNKHM+++ I D KT+ ++PIIQGF+Q++ N + N + L+SRR+R+RAGTR++RRGVDE GN ANYVETEQ L + H +SF Q+RGSVP++WSQ KY PP L+R E Q+AF+ HF EL Y +V +VNLV+ + E+ I DAY H+IK N+ ++ V FDFHDYCRG++F+NVS LI V M + W D+ G+IC QKS+FRVNC+DCLDRTNVVQ + V+E+QL KLGL P +P +WANNGD +SRQY+GT A+KGD+TRTG R ++G++KDGM+S +R++++ + RQ IDL+ G
Sbjct: 1 MEVFQTDSHYIFVKRDKSLWWHRRTSEFSIKAGWDLSSVDDIECIGVTHGIVGVISLPNVYEPHLVVVKEASAVG---VLYPPHLVYKIKSICILSADDPDTDLPNCTKHTKSNQSTPTHSVSTSNNNNASVPSSGGGSSKSTKLFEGMNKTWGAVKSAGNTIKNTTQQAANLATKQ----VKSSVGIREPRHIERRITEELHKIFDET---DSFYFSFD----CDITNNLQRHEAKSEESQS----QPDERFFWNKHMIRDLINLND----KTW-----------------------------ILPIIQGFMQVE------------NCVIGN---------ECFTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQILSFRH----HQLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAETQQAFELHFTKELETYGRVCIVNLVEQS--GKEKTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGMRFENVSALIDAVGPEAGAMGFHWRDQRGMICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQLVKLGLSPPYTPIPEQLKSPFMVLWANNGDIISRQYAGTNALKGDYTRTGERKISGMMKDGMNSANRFFIQNFADSFRQCIIDLMQG 565
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Zebrafish
Match: inpp5f (inositol polyphosphate-5-phosphatase F [Source:NCBI gene;Acc:570007]) HSP 1 Score: 457.603 bits (1176), Expect = 3.953e-139 Identity = 296/761 (38.90%), Postives = 449/761 (59.00%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLI---KQKEDNIKELANQCKKACLKTNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ +G AL+C R G ++ A ++ WNPVCLG ++G IGK++ D L+LI + VG+ P V++I+KI I L+ +L+++LCK+HHFGI K +RIT D K LMK + NV PI + +++ER ERR+L+E K+F ++ D FY + D+T+ +QRQ + S+ PLW+R D+RFFWNKHM+++ ++ + ++ +IPIIQGFVQ++ +N S P P +D H V LISRR+R+RAG R++RRGVD +G+VANYVETEQ + V + H +SFVQ RGSVPVFWSQ +Y+P +E+ E E F HFE E+ Y+K+V++NLVD N E+ I DAYL+ ++ +N+P +T V FDFH++CRG++F+NV L + I DM+++WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A V++E QL+KLG++ PE+ LP Y+I Q MWANNGD +SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R R+ RQA IDL++G+ + ++ ++ S + E+K + ++ + L + L +E+ G LI C+ + + +D++ + L++ Y+V+ D + + L L+ ++KI+IG E +F + + +R++Y
Sbjct: 1 MELFQAKDHYILQSGDNALWCSRKDGSMAVRPATDLLLAWNPVCLGLVEGIIGKMQLHVDLPLGLILIRQKALVGQLPGDHKVYKITKIVVIPLSEDEPQDLELELCKKHHFGINKPERITQSPDETKFLMKTLSQIKSNVG----------APIKKKVKE-NKEKERLERRLLDELYKIFMDS---DSFYYSL----TYDLTNTVQRQGELG-KSDQPLWKRVDDRFFWNKHMIKDLVD------------------------------LQAPQVDFWVIPIIQGFVQVEELVVNYNESSDEERSSPETPLQEPTCVDDIHP-RFTVALISRRSRHRAGMRYKRRGVDTDGHVANYVETEQLIHVHS----HTLSFVQTRGSVPVFWSQAGYRYNPRPRIEKGERETMPYFASHFEKEVETYKKLVIINLVDQN--GREKIIGDAYLKQVLLYNNPNLTYVSFDFHEHCRGMKFENVQTLTDAIYDIITDMRWAWVDQAGVICQQEGIFRVNCMDCLDRTNVVQAAIARVIMEQQLKKLGVMPPEQPLPLKCYRIYQVMWANNGDTISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVIDLMMGHPVTEDLYSIFSKEKEHEEKEKESQRGAQEQVSLLLQTYMQLLLPDDEKFHGGWALIDCDPSLIDATHKDVDVLLLLS-NSAYYVA--------YYDEEADKVNQYQRLSLEGLEKIEIGPEPTLFGKPKYCCMRLHY 696
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Zebrafish
Match: sacm1la (SAC1 like phosphatidylinositide phosphatase a [Source:NCBI gene;Acc:558940]) HSP 1 Score: 214.542 bits (545), Expect = 1.149e-58 Identity = 153/448 (34.15%), Postives = 237/448 (52.90%), Query Frame = 1
Query: 607 NGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNN-PLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXX--XXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINL 1932
N D FY C D D+T QR + + L RAD+RF WN ++L+E I + L + P+I GF+ +KP +N +E I+ ISRR+ RAG R+ RG+D G+ AN+VETEQ ++ N ++ SFVQ RGS+P FWSQ +LKY P ++ + + + + ++HFE+++ Y K V++NLV N + SE + A+ + + + I + FDFH C +++ + IL+ V+ + + Y V +G ++ EQ FR NC+DCLDRTNV+Q +LA +++QL+++G+L + ++F +I ++ WA+N +A ++QY+GT A+K DFTRTG RT GLV DG +SM RYY + RQ +IDL +GN S E +L
Sbjct: 126 NTDGFYFCTDY----DLTHTQQRLSNTSPDFQEMSLLERADQRFMWNGNLLREIIAQPE--------------------------------LHKFAFPVIHGFIVMKPCCINGKV-------------------FEWII--ISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVQFNNARA----SFVQTRGSIPFFWSQRPNLKYKPKPLISK-DTNHMDGLRRHFESQVLIYGKQVILNLV--NQKGSELPLEQAFAKMVSSMENGFIKYIAFDFHKECSKMRWHRLQILVDAVSDMQEEFGYFMVSSDGKVLSEQSGTFRSNCMDCLDRTNVIQSLLARRSLQSQLQRMGVLHVGQKIEEQADFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHWGLVMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDETDSL 509
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Zebrafish
Match: sacm1lb (SAC1 like phosphatidylinositide phosphatase b [Source:NCBI gene;Acc:791142]) HSP 1 Score: 202.216 bits (513), Expect = 2.090e-54 Identity = 146/444 (32.88%), Postives = 231/444 (52.03%), Query Frame = 1
Query: 607 NGDCFYLCYDSEKSCDITSNIQR-QKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLI-CEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXX--XXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVE 1920
N D FY D D+T +QR S L RAD+RF WN H+L+E + + L + P+I GF+ ++ +N K+ + LISRR+ RAG R+ RG+D G+ AN+VETEQ ++ K+ SF+Q RGS+P +WSQ +LKY P + +S + + F++HF++++ Y K V++NLV N + SE+ + A+ + + + I + FDFH C +++ + IL+ V ++ + Y VD +G + +Q FR NC+DCLDRTNV+Q +LA +++QL ++ +L + ++F +I ++ WA+N +A ++QY+GT A+K DFTRTG RT GL+ DG +SM RYY + RQ +IDL +GN + E
Sbjct: 126 NTDGFYFATDY----DLTHTLQRLSNTSPEFQEMTLLERADQRFVWNGHLLREFMAQPE--------------------------------LHRFVFPVIHGFIAMRS--------CCINGKIFDW-------------NLISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIIQYNGAKA----SFIQTRGSIPFYWSQRPNLKYKPKPQISKSIN-HLDGFQRHFDSQIITYGKQVILNLV--NQKGSEKPLEQAFAKMVGSLGNGMIKYIAFDFHKECSRMRWHRLQILVDTVAELQDEFGYFLVDSDGSVQMQQDGTFRSNCMDCLDRTNVIQSLLARRSLQSQLERMAVLHVGQRIEEQADFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQWGLLMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYAVEE 505
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Zebrafish
Match: synj1 (synaptojanin 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9180]) HSP 1 Score: 142.51 bits (358), Expect = 1.361e-33 Identity = 90/278 (32.37%), Postives = 156/278 (56.12%), Query Frame = 1
Query: 1078 VDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPP-IILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHL-IKFNSPKITCVMFDFHDYCRGLQFDNVSILIKG-VTKIFRDMKY-SWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLI 1896
+++G VAN+VETEQ + +++ S SF+QIRGS+P+FW Q ++ + L R E N AF++HF A Y K +++NL+ ++ E ++ A+ HL +S + + FD+H +G + + + ++K ++K D + + + G+ Q R NC+DCLDRTN VQ +A ++ QL +G L+ + L + F ++ +SMW+ NGD++S+ Y+GT A+ G + G +KDG S++R + S+Q AID++
Sbjct: 221 TNDDGQVANFVETEQIIFLDDKVS----SFIQIRGSIPLFWEQPGIQVGSHRVKLSRGFEANAPAFERHFSALKRLYGKQLIINLL--GMKEGEHMLSKAFQSHLKASEHSNAVKMLNFDYHQMVKGGKTEKLQTVLKPQISKFVEDCDFFYYSGETGIQRCQSGTIRSNCLDCLDRTNSVQAFIALEMLPKQLEAMG-LTEKPQLVARFQEVFRSMWSTNGDSISKIYAGTGALDG-------KAKGGKLKDGARSVTRTIQNNFFDSSKQEAIDIL 484
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Zebrafish
Match: synj1 (synaptojanin 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9180]) HSP 1 Score: 142.51 bits (358), Expect = 1.531e-33 Identity = 90/278 (32.37%), Postives = 156/278 (56.12%), Query Frame = 1
Query: 1078 VDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPP-IILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHL-IKFNSPKITCVMFDFHDYCRGLQFDNVSILIKG-VTKIFRDMKY-SWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLI 1896
+++G VAN+VETEQ + +++ S SF+QIRGS+P+FW Q ++ + L R E N AF++HF A Y K +++NL+ ++ E ++ A+ HL +S + + FD+H +G + + + ++K ++K D + + + G+ Q R NC+DCLDRTN VQ +A ++ QL +G L+ + L + F ++ +SMW+ NGD++S+ Y+GT A+ G + G +KDG S++R + S+Q AID++
Sbjct: 221 TNDDGQVANFVETEQIIFLDDKVS----SFIQIRGSIPLFWEQPGIQVGSHRVKLSRGFEANAPAFERHFSALKRLYGKQLIINLL--GMKEGEHMLSKAFQSHLKASEHSNAVKMLNFDYHQMVKGGKTEKLQTVLKPQISKFVEDCDFFYYSGETGIQRCQSGTIRSNCLDCLDRTNSVQAFIALEMLPKQLEAMG-LTEKPQLVARFQEVFRSMWSTNGDSISKIYAGTGALDG-------KAKGGKLKDGARSVTRTIQNNFFDSSKQEAIDIL 484
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Xenopus
Match: spata13 (spermatogenesis associated 13 [Source:Xenbase;Acc:XB-GENE-991808]) HSP 1 Score: 236.884 bits (603), Expect = 4.558e-65 Identity = 135/335 (40.30%), Postives = 214/335 (63.88%), Query Frame = 1
Query: 1312 VVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQC----KKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
+V++NLVD E+ I DAYL+ ++ FN+P +T V FDFH++CRG++F+NV L ++ I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A V++E QL+KLG++ PE+ LP Y++ Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L ++ + N EL NQ + L +E+ G LI C+ + + + L+ L + ++++ Q +R L L+ +++I+IG E F + + + +R++Y
Sbjct: 332 IVIINLVDQ--AGREKIIGDAYLKQVLMFNNPNLTYVTFDFHEHCRGMKFENVQTLTDAISDIIVDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAVARVIMEHQLKKLGVMPPEQPLPMKCYRLYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHRESQRNHHELINQLLQNYMQMLLPDDEKFHGGWALIDCDPSLIDATHRDVEVLLLLSNCAYYVAYYDDEIDKVN-QYQR------LSLEDLERIEIGPEPTFFGKPKFSCMRLHY 656 HSP 2 Score: 147.132 bits (370), Expect = 1.618e-35 Identity = 103/296 (34.80%), Postives = 156/296 (52.70%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLN 939
MELF+ K HYI+ G AL+C R G ++ A ++ WNP+CLG ++G IGK++ D L+LI + +G P +++I+KI I L+ +L+++LCK+HHFGI K ++IT D K LMK + NV S P K+ +++ER ERR+LEE KMF ++ D FY + + D+TS++QRQ S+ S+ LW+ D+RFFWNKHM+Q+ I+ + + ++PIIQGFVQI+ +N
Sbjct: 1 MELFQAKDHYILQRGESALWCSRQDGSLTSRAATDLLLAWNPICLGLVEGIIGKVQLHTDLPWWLLLIRQKSLIGILPGGHEIYKINKIAAIPLSGAEPQDLELELCKKHHFGINKPEKITQSPDDSKFLMKTLTQIKSNV----------SAP-AKKKVKESKEKERLERRLLEELFKMFMDS---DSFYYSW----TYDLTSSVQRQS-SREKSDLLLWQTVDDRFFWNKHMIQDLIDIKVQFVW--------------------------------ILPIIQGFVQIEELVVN 245
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Xenopus
Match: spata13 (spermatogenesis associated 13 [Source:Xenbase;Acc:XB-GENE-991808]) HSP 1 Score: 238.424 bits (607), Expect = 6.270e-64 Identity = 135/335 (40.30%), Postives = 214/335 (63.88%), Query Frame = 1
Query: 1312 VVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQC----KKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
+V++NLVD E+ I DAYL+ ++ FN+P +T V FDFH++CRG++F+NV L ++ I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A V++E QL+KLG++ PE+ LP Y++ Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L ++ + N EL NQ + L +E+ G LI C+ + + + L+ L + ++++ Q +R L L+ +++I+IG E F + + + +R++Y
Sbjct: 238 IVIINLVDQ--AGREKIIGDAYLKQVLMFNNPNLTYVTFDFHEHCRGMKFENVQTLTDAISDIIVDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAVARVIMEHQLKKLGVMPPEQPLPMKCYRLYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHRESQRNHHELINQLLQNYMQMLLPDDEKFHGGWALIDCDPSLIDATHRDVEVLLLLSNCAYYVAYYDDEIDKVN-QYQR------LSLEDLERIEIGPEPTFFGKPKFSCMRLHY 562 HSP 2 Score: 72.0182 bits (175), Expect = 6.716e-12 Identity = 67/193 (34.72%), Postives = 96/193 (49.74%), Query Frame = 1
Query: 361 IDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLN 939
I LCK+HHFGI K ++IT D K LMK + NV S P K+ +++ER ERR+LEE KMF ++ D FY + + D+TS++QRQ S+ S+ LW+ D+RFFWNKHM+Q+ I+ + + ++PIIQGFVQI+ +N
Sbjct: 10 IQLCKKHHFGINKPEKITQSPDDSKFLMKTLTQIKSNV----------SAP-AKKKVKESKEKERLERRLLEELFKMFMDS---DSFYYSW----TYDLTSSVQRQS-SREKSDLLLWQTVDDRFFWNKHMIQDLIDIKVQFVW--------------------------------ILPIIQGFVQIEELVVN 151
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Xenopus
Match: spata13 (spermatogenesis associated 13 [Source:Xenbase;Acc:XB-GENE-991808]) HSP 1 Score: 237.654 bits (605), Expect = 1.384e-63 Identity = 135/335 (40.30%), Postives = 214/335 (63.88%), Query Frame = 1
Query: 1312 VVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQC----KKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
+V++NLVD E+ I DAYL+ ++ FN+P +T V FDFH++CRG++F+NV L ++ I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A V++E QL+KLG++ PE+ LP Y++ Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L ++ + N EL NQ + L +E+ G LI C+ + + + L+ L + ++++ Q +R L L+ +++I+IG E F + + + +R++Y
Sbjct: 269 IVIINLVDQ--AGREKIIGDAYLKQVLMFNNPNLTYVTFDFHEHCRGMKFENVQTLTDAISDIIVDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAVARVIMEHQLKKLGVMPPEQPLPMKCYRLYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHRESQRNHHELINQLLQNYMQMLLPDDEKFHGGWALIDCDPSLIDATHRDVEVLLLLSNCAYYVAYYDDEIDKVN-QYQR------LSLEDLERIEIGPEPTFFGKPKFSCMRLHY 593 HSP 2 Score: 81.2629 bits (199), Expect = 9.924e-15 Identity = 37/106 (34.91%), Postives = 62/106 (58.49%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDL 369
MELF+ K HYI+ G AL+C R G ++ A ++ WNP+CLG ++G IGK++ D L+LI + +G P +++I+KI I L+ +L++++
Sbjct: 1 MELFQAKDHYILQRGESALWCSRQDGSLTSRAATDLLLAWNPICLGLVEGIIGKVQLHTDLPWWLLLIRQKSLIGILPGGHEIYKINKIAAIPLSGAEPQDLELEV 106
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Xenopus
Match: spata13 (spermatogenesis associated 13 [Source:Xenbase;Acc:XB-GENE-991808]) HSP 1 Score: 236.884 bits (603), Expect = 3.869e-63 Identity = 135/334 (40.42%), Postives = 213/334 (63.77%), Query Frame = 1
Query: 1315 VVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQC----KKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
V++NLVD E+ I DAYL+ ++ FN+P +T V FDFH++CRG++F+NV L ++ I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A V++E QL+KLG++ PE+ LP Y++ Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L ++ + N EL NQ + L +E+ G LI C+ + + + L+ L + ++++ Q +R L L+ +++I+IG E F + + + +R++Y
Sbjct: 324 VIINLVDQ--AGREKIIGDAYLKQVLMFNNPNLTYVTFDFHEHCRGMKFENVQTLTDAISDIIVDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAVARVIMEHQLKKLGVMPPEQPLPMKCYRLYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHRESQRNHHELINQLLQNYMQMLLPDDEKFHGGWALIDCDPSLIDATHRDVEVLLLLSNCAYYVAYYDDEIDKVN-QYQR------LSLEDLERIEIGPEPTFFGKPKFSCMRLHY 647 HSP 2 Score: 118.242 bits (295), Expect = 4.638e-26 Identity = 89/264 (33.71%), Postives = 137/264 (51.89%), Query Frame = 1
Query: 148 ANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLN 939
A ++ WNP+CLG ++G IGK++ D L+LI + +G P +++I+KI I L+ +L+++LCK+HHFGI K ++IT D K LMK + NV S P K+ +++ER ERR+LEE KMF ++ D FY + + D+TS++QRQ S+ S+ LW+ D+RFFWNKHM+Q+ I+ + + ++PIIQGFVQI+ +N
Sbjct: 13 ATDLLLAWNPICLGLVEGIIGKVQLHTDLPWWLLLIRQKSLIGILPGGHEIYKINKIAAIPLSGAEPQDLELELCKKHHFGINKPEKITQSPDDSKFLMKTLTQIKSNV----------SAP-AKKKVKESKEKERLERRLLEELFKMFMDS---DSFYYSW----TYDLTSSVQRQS-SREKSDLLLWQTVDDRFFWNKHMIQDLIDIKVQFVW--------------------------------ILPIIQGFVQIEELVVN 225
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Xenopus
Match: spata13 (spermatogenesis associated 13 [Source:Xenbase;Acc:XB-GENE-991808]) HSP 1 Score: 236.884 bits (603), Expect = 3.942e-63 Identity = 135/334 (40.42%), Postives = 213/334 (63.77%), Query Frame = 1
Query: 1315 VVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQC----KKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
V++NLVD E+ I DAYL+ ++ FN+P +T V FDFH++CRG++F+NV L ++ I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A V++E QL+KLG++ PE+ LP Y++ Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L ++ + N EL NQ + L +E+ G LI C+ + + + L+ L + ++++ Q +R L L+ +++I+IG E F + + + +R++Y
Sbjct: 317 VIINLVDQ--AGREKIIGDAYLKQVLMFNNPNLTYVTFDFHEHCRGMKFENVQTLTDAISDIIVDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAVARVIMEHQLKKLGVMPPEQPLPMKCYRLYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHRESQRNHHELINQLLQNYMQMLLPDDEKFHGGWALIDCDPSLIDATHRDVEVLLLLSNCAYYVAYYDDEIDKVN-QYQR------LSLEDLERIEIGPEPTFFGKPKFSCMRLHY 640 HSP 2 Score: 104.375 bits (259), Expect = 8.833e-22 Identity = 93/296 (31.42%), Postives = 139/296 (46.96%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLN 939
MELF+ K HYI+ G AL+C R G ++ AD L+LI + +G P +++I+KI I L+ +L+++LCK+HHFGI K ++IT D K LMK + NV S P K+ +++ER ERR+LEE KMF ++ D FY + + D+TS++QRQ S+ S+ LW+ D+RFFWNKHM+Q+ I+ + + ++PIIQGFVQI+ +N
Sbjct: 1 MELFQAKDHYILQRGESALWCSRQDGSLT---------------------------SRADLPWWLLLIRQKSLIGILPGGHEIYKINKIAAIPLSGAEPQDLELELCKKHHFGINKPEKITQSPDDSKFLMKTLTQIKSNV----------SAP-AKKKVKESKEKERLERRLLEELFKMFMDS---DSFYYSW----TYDLTSSVQRQS-SREKSDLLLWQTVDDRFFWNKHMIQDLIDIKVQFVW--------------------------------ILPIIQGFVQIEELVVN 218
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Mouse
Match: Inpp5f (inositol polyphosphate-5-phosphatase F [Source:MGI Symbol;Acc:MGI:2141867]) HSP 1 Score: 448.358 bits (1152), Expect = 1.244e-135 Identity = 298/760 (39.21%), Postives = 450/760 (59.21%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKA----CLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ G AL+C R G + A ++ WNP+CLG ++G IGKI+ +D L+LI + VG+ P V +++KI +SL+ + L+++LCK+HHFGI K ++I D K L+K F NV S P K+ +++E+ ERR+LEE KMF ++E+ FY + D+T+++QRQ + + PLW++ D+RFFWNK+M+Q E I ++ +IPIIQGFVQI+ +N S + P P +D H +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V + H +SF+Q RGSVPVFWSQ +Y+P L++SE+E + F HFE +L Y+K V+VNLVD E+ I DAYL+ ++ FN+PK+T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP + Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L K+ + + +EL +Q ++ L +E+ G L+ C+ + + + L+ L + ++++ Q +R L L+ +++I+IG E +F + + + +R++Y
Sbjct: 1 MELFQAKDHYILQQGERALWCSRRDGGLQLRPATDLLLAWNPICLGLVEGVIGKIQLHSDLPWWLILIRQKALVGKLPGDHEVCKVTKIAVLSLSEMEPQELELELCKKHHFGINKPEKIIPSPDDSKFLLKTFTNIKSNV----------SAP-NKKKVKESKEKEKLERRLLEELLKMFMDSES---FYYSL----TYDLTNSVQRQSTGERD-GRPLWQKVDDRFFWNKYMIQALTE------------------------------IGTPDVDFWIIPIIQGFVQIEELVVNYNESSDDDKSSPETPPQDSTCVDDIHP-RFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHH----HTLSFIQTRGSVPVFWSQVGYRYNPRPRLDKSEKETVDCFCAHFEEQLKIYKKQVIVNLVDQ--AGREKIIGDAYLKQVLLFNNPKLTYVSFDFHEHCRGMKFENVQTLTDAIHDIIIDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRTYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLSRFKDAYRQAVIDLMQGVPVTEDLYSIFTKEKEHE-ALHKESQRSHQELISQLLQSYMQLLLPGDEKFHGGWALVDCDPSLTDAAHRDVEVLLLLSNAAYYVAYYDDEVDKVN-QYQR------LGLEDLERIEIGPEPTLFGKPKFSCMRLHY 696
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Mouse
Match: Sacm1l (SAC1 suppressor of actin mutations 1-like (yeast) [Source:MGI Symbol;Acc:MGI:1933169]) HSP 1 Score: 206.068 bits (523), Expect = 1.155e-55 Identity = 148/445 (33.26%), Postives = 230/445 (51.69%), Query Frame = 1
Query: 613 DCFYLCYDSEKSCDITSNIQR-QKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKY--HPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXN--FYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEI 1923
D FY + D+T +QR S L RAD+RF WN H+L+E + + +P++ GF+ + +N ++ I LISRR+ RAG R+ RG+D G+ AN+VETEQ + +++ SFVQ RGS+P+FWSQ +LKY HP I + + F++HF++++ Y K V++NLV N + SE+ + + + S I + FDFH C+ +++D +SIL+ V ++ ++ Y VD G ++ Q +FR NC+DCLDRTNV+Q +LA ++ QL++LG+L + L F + ++ WA+N +A ++QY+GT A+K DFTRTG RT GL+ DG +S+ RYY + RQ +IDL +GN S E+
Sbjct: 129 DGFYF----STTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPE--------------------------------VHRFALPVLHGFITMHSCSIN-------------------GKYFDWI--LISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYSGNRA----SFVQTRGSIPIFWSQRPNLKYKPHPQI---SKVANHMDGFQRHFDSQVIIYGKQVIINLV--NHKGSEKPLEQTFANMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGKVVTNQDGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKTYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLLMDGFNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDEL 507
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Mouse
Match: Sacm1l (SAC1 suppressor of actin mutations 1-like (yeast) [Source:MGI Symbol;Acc:MGI:1933169]) HSP 1 Score: 206.068 bits (523), Expect = 1.155e-55 Identity = 148/445 (33.26%), Postives = 230/445 (51.69%), Query Frame = 1
Query: 613 DCFYLCYDSEKSCDITSNIQR-QKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKY--HPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXN--FYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEI 1923
D FY + D+T +QR S L RAD+RF WN H+L+E + + +P++ GF+ + +N ++ I LISRR+ RAG R+ RG+D G+ AN+VETEQ + +++ SFVQ RGS+P+FWSQ +LKY HP I + + F++HF++++ Y K V++NLV N + SE+ + + + S I + FDFH C+ +++D +SIL+ V ++ ++ Y VD G ++ Q +FR NC+DCLDRTNV+Q +LA ++ QL++LG+L + L F + ++ WA+N +A ++QY+GT A+K DFTRTG RT GL+ DG +S+ RYY + RQ +IDL +GN S E+
Sbjct: 129 DGFYF----STTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPE--------------------------------VHRFALPVLHGFITMHSCSIN-------------------GKYFDWI--LISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYSGNRA----SFVQTRGSIPIFWSQRPNLKYKPHPQI---SKVANHMDGFQRHFDSQVIIYGKQVIINLV--NHKGSEKPLEQTFANMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGKVVTNQDGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKTYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLLMDGFNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDEL 507
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Mouse
Match: Sacm1l (SAC1 suppressor of actin mutations 1-like (yeast) [Source:MGI Symbol;Acc:MGI:1933169]) HSP 1 Score: 205.682 bits (522), Expect = 2.350e-55 Identity = 148/445 (33.26%), Postives = 230/445 (51.69%), Query Frame = 1
Query: 613 DCFYLCYDSEKSCDITSNIQR-QKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKY--HPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXN--FYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEI 1923
D FY + D+T +QR S L RAD+RF WN H+L+E + + +P++ GF+ + +N ++ I LISRR+ RAG R+ RG+D G+ AN+VETEQ + +++ SFVQ RGS+P+FWSQ +LKY HP I + + F++HF++++ Y K V++NLV N + SE+ + + + S I + FDFH C+ +++D +SIL+ V ++ ++ Y VD G ++ Q +FR NC+DCLDRTNV+Q +LA ++ QL++LG+L + L F + ++ WA+N +A ++QY+GT A+K DFTRTG RT GL+ DG +S+ RYY + RQ +IDL +GN S E+
Sbjct: 129 DGFYF----STTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPE--------------------------------VHRFALPVLHGFITMHSCSIN-------------------GKYFDWI--LISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYSGNRA----SFVQTRGSIPIFWSQRPNLKYKPHPQI---SKVANHMDGFQRHFDSQVIIYGKQVIINLV--NHKGSEKPLEQTFANMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGKVVTNQDGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKTYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLLMDGFNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDEL 507
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Mouse
Match: Synj1 (synaptojanin 1 [Source:MGI Symbol;Acc:MGI:1354961]) HSP 1 Score: 148.288 bits (373), Expect = 4.997e-36 Identity = 105/328 (32.01%), Postives = 178/328 (54.27%), Query Frame = 1
Query: 1078 VDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPII-LERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHL-IKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAID-LIIGNESSVEIIN-----LRSGRNDTEQKLIKQKEDNIKELANQCK-KACLKT 2031
+++G+VAN+VETEQ + +++ S SF+QIRGSVP+FW Q L+ + + R E N AF +HF + Y K +VVNL+ + + E ++ A+ HL ++ I V FD+H +G + + + ++K + F D + + D + + Q R NC+DCLDRTN VQ L ++ QL LG L+ + L + F ++ +SMW+ NGD++S+ Y+GT A++G + G +KDG S++R + S+Q AID L++GN + ++ + L +G K++K +N + + K + C+ T
Sbjct: 221 TNDDGHVANFVETEQVIYLDDCVS----SFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKDLYGKQIVVNLLGS--KEGEHMLSKAFQSHLKASEHASDIHMVSFDYHQMVKGGKAEKLHSILKPQVQKFLDYGFFYFDGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALG-LAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALEG-------KAKAGKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRASSKVLKNMCENFYKYSKPKKIRVCVGT 534
BLAST of phosphatidylinositide phosphatase SAC2 vs. UniProt/SwissProt
Match: sp|A8E7C5|SAC2_DANRE (Phosphatidylinositide phosphatase SAC2 OS=Danio rerio OX=7955 GN=inpp5f PE=3 SV=1) HSP 1 Score: 457.603 bits (1176), Expect = 2.984e-138 Identity = 296/761 (38.90%), Postives = 449/761 (59.00%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLI---KQKEDNIKELANQCKKACLKTNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ +G AL+C R G ++ A ++ WNPVCLG ++G IGK++ D L+LI + VG+ P V++I+KI I L+ +L+++LCK+HHFGI K +RIT D K LMK + NV PI + +++ER ERR+L+E K+F ++ D FY + D+T+ +QRQ + S+ PLW+R D+RFFWNKHM+++ ++ + ++ +IPIIQGFVQ++ +N S P P +D H V LISRR+R+RAG R++RRGVD +G+VANYVETEQ + V + H +SFVQ RGSVPVFWSQ +Y+P +E+ E E F HFE E+ Y+K+V++NLVD N E+ I DAYL+ ++ +N+P +T V FDFH++CRG++F+NV L + I DM+++WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A V++E QL+KLG++ PE+ LP Y+I Q MWANNGD +SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R R+ RQA IDL++G+ + ++ ++ S + E+K + ++ + L + L +E+ G LI C+ + + +D++ + L++ Y+V+ D + + L L+ ++KI+IG E +F + + +R++Y
Sbjct: 1 MELFQAKDHYILQSGDNALWCSRKDGSMAVRPATDLLLAWNPVCLGLVEGIIGKMQLHVDLPLGLILIRQKALVGQLPGDHKVYKITKIVVIPLSEDEPQDLELELCKKHHFGINKPERITQSPDETKFLMKTLSQIKSNVG----------APIKKKVKE-NKEKERLERRLLDELYKIFMDS---DSFYYSL----TYDLTNTVQRQGELG-KSDQPLWKRVDDRFFWNKHMIKDLVD------------------------------LQAPQVDFWVIPIIQGFVQVEELVVNYNESSDEERSSPETPLQEPTCVDDIHP-RFTVALISRRSRHRAGMRYKRRGVDTDGHVANYVETEQLIHVHS----HTLSFVQTRGSVPVFWSQAGYRYNPRPRIEKGERETMPYFASHFEKEVETYKKLVIINLVDQN--GREKIIGDAYLKQVLLYNNPNLTYVSFDFHEHCRGMKFENVQTLTDAIYDIITDMRWAWVDQAGVICQQEGIFRVNCMDCLDRTNVVQAAIARVIMEQQLKKLGVMPPEQPLPLKCYRIYQVMWANNGDTISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVIDLMMGHPVTEDLYSIFSKEKEHEEKEKESQRGAQEQVSLLLQTYMQLLLPDDEKFHGGWALIDCDPSLIDATHKDVDVLLLLS-NSAYYVA--------YYDEEADKVNQYQRLSLEGLEKIEIGPEPTLFGKPKYCCMRLHY 696
BLAST of phosphatidylinositide phosphatase SAC2 vs. UniProt/SwissProt
Match: sp|Q9Y2H2|SAC2_HUMAN (Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3) HSP 1 Score: 451.825 bits (1161), Expect = 4.617e-136 Identity = 302/762 (39.63%), Postives = 455/762 (59.71%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLK----TNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ G AL+C R G + A ++ WNP+CLG ++G IGKI+ +D L+LI + VG+ P V +++KI +SL+ + +L+++LCK+HHFGI K ++I D K L+K F NV S P K+ +++E+ ERR+LEE KMF ++E+ FY + D+T+++QRQ + + PLW++ D+RFFWNK+M+Q+ E I ++ +IP+IQGFVQI+ +N S P P +D H +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V N H +SFVQ RGSVPVFWSQ +Y+P L+RSE+E F HFE +LN Y+K V++NLVD E+ I DAYL+ ++ FN+ +T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP +I Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L K+ + + +EL +Q ++ +K +E+ G LI C+ + + +D++ + L++ Y+V+ D + + L L++++KI+IG E +F + + + +R++Y
Sbjct: 1 MELFQAKDHYILQQGERALWCSRRDGGLQLRPATDLLLAWNPICLGLVEGVIGKIQLHSDLPWWLILIRQKALVGKLPGDHEVCKVTKIAVLSLSEMEPQDLELELCKKHHFGINKPEKIIPSPDDSKFLLKTFTHIKSNV----------SAP-NKKKVKESKEKEKLERRLLEELLKMFMDSES---FYYSL----TYDLTNSVQRQSTGERD-GRPLWQKVDDRFFWNKYMIQDLTE------------------------------IGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHP-RFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHN----HTLSFVQTRGSVPVFWSQVGYRYNPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQ--AGREKIIGDAYLKQVLLFNNSHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHKENQRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHRDVDVLLLLS-NSAYYVA--------YYDDEVDKVNQYQRLSLENLEKIEIGPEPTLFGKPKFSCMRLHY 696
BLAST of phosphatidylinositide phosphatase SAC2 vs. UniProt/SwissProt
Match: sp|Q8CDA1|SAC2_MOUSE (Phosphatidylinositide phosphatase SAC2 OS=Mus musculus OX=10090 GN=Inpp5f PE=1 SV=1) HSP 1 Score: 448.358 bits (1152), Expect = 8.705e-135 Identity = 298/760 (39.21%), Postives = 450/760 (59.21%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKA----CLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ G AL+C R G + A ++ WNP+CLG ++G IGKI+ +D L+LI + VG+ P V +++KI +SL+ + L+++LCK+HHFGI K ++I D K L+K F NV S P K+ +++E+ ERR+LEE KMF ++E+ FY + D+T+++QRQ + + PLW++ D+RFFWNK+M+Q E I ++ +IPIIQGFVQI+ +N S + P P +D H +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V + H +SF+Q RGSVPVFWSQ +Y+P L++SE+E + F HFE +L Y+K V+VNLVD E+ I DAYL+ ++ FN+PK+T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP + Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L K+ + + +EL +Q ++ L +E+ G L+ C+ + + + L+ L + ++++ Q +R L L+ +++I+IG E +F + + + +R++Y
Sbjct: 1 MELFQAKDHYILQQGERALWCSRRDGGLQLRPATDLLLAWNPICLGLVEGVIGKIQLHSDLPWWLILIRQKALVGKLPGDHEVCKVTKIAVLSLSEMEPQELELELCKKHHFGINKPEKIIPSPDDSKFLLKTFTNIKSNV----------SAP-NKKKVKESKEKEKLERRLLEELLKMFMDSES---FYYSL----TYDLTNSVQRQSTGERD-GRPLWQKVDDRFFWNKYMIQALTE------------------------------IGTPDVDFWIIPIIQGFVQIEELVVNYNESSDDDKSSPETPPQDSTCVDDIHP-RFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHH----HTLSFIQTRGSVPVFWSQVGYRYNPRPRLDKSEKETVDCFCAHFEEQLKIYKKQVIVNLVDQ--AGREKIIGDAYLKQVLLFNNPKLTYVSFDFHEHCRGMKFENVQTLTDAIHDIIIDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRTYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLSRFKDAYRQAVIDLMQGVPVTEDLYSIFTKEKEHE-ALHKESQRSHQELISQLLQSYMQLLLPGDEKFHGGWALVDCDPSLTDAAHRDVEVLLLLSNAAYYVAYYDDEVDKVN-QYQR------LGLEDLERIEIGPEPTLFGKPKFSCMRLHY 696
BLAST of phosphatidylinositide phosphatase SAC2 vs. UniProt/SwissProt
Match: sp|A4VCH0|SAC1A_DANRE (Phosphatidylinositide phosphatase SAC1-A OS=Danio rerio OX=7955 GN=sacm1la PE=2 SV=2) HSP 1 Score: 214.542 bits (545), Expect = 8.676e-58 Identity = 153/448 (34.15%), Postives = 237/448 (52.90%), Query Frame = 1
Query: 607 NGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNN-PLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXX--XXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINL 1932
N D FY C D D+T QR + + L RAD+RF WN ++L+E I + L + P+I GF+ +KP +N +E I+ ISRR+ RAG R+ RG+D G+ AN+VETEQ ++ N ++ SFVQ RGS+P FWSQ +LKY P ++ + + + + ++HFE+++ Y K V++NLV N + SE + A+ + + + I + FDFH C +++ + IL+ V+ + + Y V +G ++ EQ FR NC+DCLDRTNV+Q +LA +++QL+++G+L + ++F +I ++ WA+N +A ++QY+GT A+K DFTRTG RT GLV DG +SM RYY + RQ +IDL +GN S E +L
Sbjct: 126 NTDGFYFCTDY----DLTHTQQRLSNTSPDFQEMSLLERADQRFMWNGNLLREIIAQPE--------------------------------LHKFAFPVIHGFIVMKPCCINGKV-------------------FEWII--ISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVQFNNARA----SFVQTRGSIPFFWSQRPNLKYKPKPLISK-DTNHMDGLRRHFESQVLIYGKQVILNLV--NQKGSELPLEQAFAKMVSSMENGFIKYIAFDFHKECSKMRWHRLQILVDAVSDMQEEFGYFMVSSDGKVLSEQSGTFRSNCMDCLDRTNVIQSLLARRSLQSQLQRMGVLHVGQKIEEQADFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHWGLVMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYSVDETDSL 509
BLAST of phosphatidylinositide phosphatase SAC2 vs. UniProt/SwissProt
Match: sp|Q9ES21|SAC1_RAT (Phosphatidylinositide phosphatase SAC1 OS=Rattus norvegicus OX=10116 GN=Sacm1l PE=1 SV=1) HSP 1 Score: 210.69 bits (535), Expect = 2.161e-56 Identity = 149/443 (33.63%), Postives = 233/443 (52.60%), Query Frame = 1
Query: 613 DCFYLCYDSEKSCDITSNIQR-QKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXN--FYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEI 1923
D FY + D+T +QR S L RAD+RF WN H+L+E + + +P++ GF+ + +N ++ I LISRR+ RAG R+ RG+D G+ AN+VETEQ + +++ SFVQ RGS+PVFWSQ +LKY P + + + + F++HF++++ Y K V++NLV N + SE+ + + + + S I + FDFH C+ +++D +SIL+ V ++ ++ Y VD G ++ Q+ +FR NC+DCLDRTNV+Q +LA ++ QL++LG+L + L F +I ++ WA+N +A ++QY+GT A+K DFTRTG RT GLV DG +S+ RYY + RQ +IDL +GN S E+
Sbjct: 129 DGFYF----STTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLLRELSAQPE--------------------------------VHRFALPVLHGFITMHSCSIN-------------------GKYFDWI--LISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVHYSGNRA----SFVQTRGSIPVFWSQRPNLKYKPDPQINKVAN-HMDGFQRHFDSQVIIYGKQVIINLV--NHKGSEKPLEQTFAKMVSSLGSGMIRYIAFDFHKECKNMRWDRLSILLDQVAEMQDELSYFLVDSAGKVVTNQEGVFRSNCMDCLDRTNVIQSLLARRSLQAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQLGLVMDGFNSLLRYYKNNFSDGFRQDSIDLFLGNYSVDEL 507
BLAST of phosphatidylinositide phosphatase SAC2 vs. TrEMBL
Match: A0A1S3IQG5 (phosphatidylinositide phosphatase SAC2 OS=Lingula unguis OX=7574 GN=LOC106166443 PE=4 SV=1) HSP 1 Score: 519.62 bits (1337), Expect = 1.598e-158 Identity = 333/848 (39.27%), Postives = 484/848 (57.08%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKL-NLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIFRLRQNMIRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAAAKVTNPNVIFDETLQKFEKSKSNPIPS 2589
MELFE + HYII G +L+C R G + +++ WNPVCLG + G IGK + D + +LMLI VG+ V+RI+K+ + L LD+ LCK+HHFGIKKT RI + D Q+ + H+K+V R + K+V+DRERFER++ EE KMF E D FY S D+TS++QRQ S YN+ +PLW+RAD RFFWN+ ML+E + S + L + ++P+ QG++QI ++ N S ++ M+ + + +ISRR+R+RAGTRF+RRGVDE+G VANYVETEQ ++ PH+VSFVQ+RGS+PV+WSQ +Y PP L+R E E+Q+AF H + +L+ Y+KV VNLVD E+ +ADA+L+H++ +NS +T V + FHDYCRG++F+NVSIL + I +D++Y WVD NG+ICEQ+ + RVNCVDCLDRTNVVQ +A +V+ETQ RKLGLL PEE LP+ + Q MWANNGD +SRQY+GT A+KGD+TRTG R G++KDGM S +RY+ R ++ RQA ID++ G + + ++ L + + +++KE+ +K + +Q KK L +++CLG LI ++ DM+T+ L+T Y S D + ++ +PL S+ I+IG E + + + IR Y N+ N + F+ + RLFNNI+I V ++ ES +AIA++F AA +T +I + +K E+ K P P
Sbjct: 1 MELFEARDHYIIQEGDNSLWCSRFDGSLVAKTGSDIVNAWNPVCLGLVHGVIGKFRILPDSDWRLMLIQERHLVGQLYRVHDVYRITKVCIVPLTPEEPGELDLQLCKKHHFGIKKTSRIASTLDQQQKTLTKTWNHLKSVAGHASR----------NKKKEVKDRERFERKVTEEILKMFNET---DSFYY----SSSTDLTSSLQRQHGSAYNTADPLWKRADLRFFWNRAMLEELVNSLEPLS------------------------------DHWIVPVTQGYIQISQCQMVNENEMSTFYTSHKDM----MRDAPQYTMTIISRRSRHRAGTRFKRRGVDESGAVANYVETEQIIEY----LPHVVSFVQVRGSIPVYWSQSGYRYRPPPRLDRDESESQKAFATHMKEQLDIYQKVCAVNLVDQG--GREKVLADAFLRHVLLYNSKDVTYVSYAFHDYCRGMRFENVSILTDNLQDIIKDIRYCWVDPNGMICEQRGVIRVNCVDCLDRTNVVQTAIARIVLETQCRKLGLLLPEEDLPTECRLVFQQMWANNGDTISRQYAGTVALKGDYTRTGERKFTGVMKDGMHSANRYFQNRFKDAYRQATIDILQGLKVTEDLSALNKAGPEDDSSFLQEKEEYVKVMIDQSKKLLLSDDQDCLGGWALIDMENSDSGQTDMDTILLLTQTHFYVAS---------YDDEAEKVTQFQKIPLDSLLSIEIGPEPAVLKSKFQCIRFNY------------------------RNQQQNYSYTFRSTNSRLFNNIVIAVTNQDEAKESFRAIAQTFAAAIGLTGRQLIIMD--KKLERKKYKPHPG 756
BLAST of phosphatidylinositide phosphatase SAC2 vs. TrEMBL
Match: A0A218UQG6 (Phosphatidylinositide phosphatase SAC2 OS=Lonchura striata domestica OX=299123 GN=INPP5F PE=4 SV=1) HSP 1 Score: 466.463 bits (1199), Expect = 3.272e-139 Identity = 298/763 (39.06%), Postives = 449/763 (58.85%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTE---QKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDF--QTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ +G AL+C R G + A ++ WNP+CLG ++G IGK++ D L+LI + +G+ P V +I+KI I L+ +L+++LCK+HHFGI K ++IT D K L+K + NV + N K +R+ + ER E++F+ + D FY S D+T+++QRQ + +N PLWR+ D+RFFWNKHM+++ I I ++ +IPIIQGFVQI+ +N S + P P +D H +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V N H +S++Q RGSVPVFWSQ +Y+P L++SE E F+ HFE +L NY+K V++NLVD E+ I DAYL+ ++ +N+ +T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP +I Q MWANNGDA+SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R R+ RQA IDL+ G + ++ ++ + + E ++ ++ ++ I +L K L +E+ G LI C+ + + +D++ + L++ Y+V+ + ID Q +R L L++++KI+IG E +F + + + +R++Y
Sbjct: 1 MELFQAKDHYILQSGERALWCSRRDGSLQLRAATDLLLAWNPICLGLVEGVIGKVQLHTDLPWWLLLIRQKALIGKLPGDHEVCKITKIAVIPLSETEPQDLELELCKKHHFGINKPEKITQSPDDTKFLLKTLTQIKSNV--------------SAPNKKKIRESKEKERLEKRLLEELFKMFMDSDSFYYSL----SYDLTNSVQRQSACE-KTNLPLWRKVDDRFFWNKHMIEDLIS------------------------------IDNAEVDFWIIPIIQGFVQIEELVVNYSESSDDDKSSPETPPQESSCVDDVHP-TFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHN----HTLSYIQTRGSVPVFWSQVGYRYNPRPRLDKSENETVSCFRAHFEEQLKNYKKQVIINLVDQT--GREKIIGDAYLKQVLLYNNANLTYVSFDFHEHCRGMKFENVQTLTDAIHDIILDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDAISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHEALHKENLRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHKDVDVLLLLS-NSAYYVAYY----DDEIDKVNQYQR------LSLEALEKIEIGPEPTLFGKPKFSCMRLHY 696
BLAST of phosphatidylinositide phosphatase SAC2 vs. TrEMBL
Match: F7D207 (Uncharacterized protein OS=Ornithorhynchus anatinus OX=9258 PE=4 SV=2) HSP 1 Score: 454.521 bits (1168), Expect = 9.732e-139 Identity = 300/762 (39.37%), Postives = 457/762 (59.97%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLK----TNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ G AL+C R G + A ++ WNP+CLG ++G IGK++ +D L+LI + +G+ P ++ +I+KI +SL+ + +L+++LCK+HHFGI K ++IT D K L+K F + NV S P K+ +++E+ ERR+LEE KMF ++E+ FY + D+T+++QRQ + N N PLW++ D+RFFWNK+MLQ+ IE + ++ ++P+IQGFVQI+ +N S P P +D H +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V N H +SF+Q RGSVPVFWSQ +Y+P L++SE+E F HFE +L Y+K V++NLVD E+ I DAYL+ ++ FN+ +T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP +I Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R ++ RQA IDL+ G + ++ ++ + + E L K+ + + +EL +Q ++ +K +E+ G LI C+ + + +D++ + L++ Y+V+ D + + L L+ ++KI+IG E F + + + +R++Y
Sbjct: 1 MELFQAKDHYILQQGERALWCSRRDGRLQLKPATDLLLAWNPICLGLVEGVIGKVQLHSDLPWWLLLIRQKSLIGKLPGDHAICKITKIAVLSLSEMEPQDLELELCKKHHFGINKPEKITQSPDDSKFLLKTFTQIKSNV----------SAP-NKKKIKESKEKEKLERRLLEELLKMFMDSES---FYYSL----TYDLTNSVQRQSACEKN-NLPLWQKVDDRFFWNKYMLQDLIEIGNS------------------------------EVDFWIVPVIQGFVQIEELVVNYNESSDDEKSSPETPPQEPCCVDDVHP-RFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHN----HTLSFIQTRGSVPVFWSQVGYRYNPRPRLDKSEKETVSYFCAHFEEQLKIYKKQVIINLVDQ--AGREKIIGDAYLKQVLLFNNSNLTYVSFDFHEHCRGMKFENVQTLTDAIHDIILDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCSRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHE-ALHKENQRSHQELVSQLLQSYMKLLLPDDEKFHGGWALIDCDPSLTDATHKDVDVLLLLS-NSAYYVA--------YYDDEVDKVNQYQRLSLEDLEKIEIGPEPTFFGKPKFSCMRLHY 696
BLAST of phosphatidylinositide phosphatase SAC2 vs. TrEMBL
Match: V5HYT9 (Putative suppressor of actin sac OS=Ixodes ricinus OX=34613 PE=2 SV=1) HSP 1 Score: 464.151 bits (1193), Expect = 1.574e-138 Identity = 300/857 (35.01%), Postives = 475/857 (55.43%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQE-HMKNVNIKPKRIPWKSEPITLSN-DKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQ-KQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLP--------NLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKE--DNIKELANQCKKACLKTNEECLGESILIFCNE--NEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIFRLRQNMIRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAAAKVTNPNVIFDETLQKFEKSKS 2574
ME+ T ++Y+I++G L+C R+ G + +++ +P+CLG I G IGK + D + +L+LI ++ +G P V++++K+ + L+ S +I+ C +HH +++ +R Q++L K + +KP++ P+ N DK +ERR+L+E KMF + + FYL + D+T+ +QRQ +Q + PLWRR D+RFFWN+ ML++ E D + G + + P++QGFVQ++ +L+ P L +L + E + L+SRR+R RAGTR++RRGVD+ G ANYVETEQ + + H VSFVQ+RGSVPVFWSQ KY PP L+R EEE ++AF KHF +L+ Y V+V+LV+ + E+ +ADAYL H++ + P++T V FDFH+YCRG++F+NVS+LI G+ + RDM+Y W+D+ GLIC Q+ +FR+NC+DCLDRTN+VQ +A ++TQ +LGLL PE LP+ +I Q +WANNGD +SRQY+GT A+KGDFTRTG+R + G++KDG +S +RYY+ R ++ RQA ID+++GN + + + + + D ++ +E +++K+L CKK + +E LG LI + + DM+++ ++T + Y D QT R + L+ ++K+++G E ++F+ R + IR++Y + N F F+ R FNN+ + + + +ESLKAI ESF A V + NV E K E+ +S
Sbjct: 1 MEILMTAEYYVIVDGEHTLWCSRIDGTLEPRKLSDLHKLTDPICLGIIYGVIGKFQPHPDSDKQLVLIRQVSLIGCLPGNHQVFKVNKVVLLPLSVHENSETEIEPCPKHHPNVRRPERSPASEFQQRALQKTWNTIKTATAQVKPRK------PVQKENRDK-------YERRLLDELAKMFNDT---NSFYL----SPTGDLTNTLQRQYEQDPQLAKAPLWRRVDDRFFWNREMLRDLTERED-----SAG-------------------------DHWIQPVVQGFVQVERCQLDTMDDGPTEAALTQDSTGTWFDLQCTERLPAKEFTMALVSRRSRYRAGTRYKRRGVDDTGQCANYVETEQIFEY----AAHTVSFVQVRGSVPVFWSQPGYKYRPPPRLDRGEEETRQAFAKHFAEQLHLYGSQVLVSLVEQTGK--EKVLADAYLNHVLLLDDPRLTYVSFDFHEYCRGMRFENVSVLIDGIKDLVRDMRYCWLDQQGLICGQRGVFRINCIDCLDRTNIVQTAIAKTAMDTQFVRLGLLPPEGVLPTACRRIFQMLWANNGDIISRQYAGTVALKGDFTRTGSRRLAGMMKDGYNSANRYYMNRFKDAYRQATIDIMLGNPVTEDFMAVSPEQEDEPILEMQDQEHHEHVKQLIEHCKKMLIPESEVVLGGWALIDADPVTGDPGQGDMDSILVLTQDSYYVAE---------YDDQTDRITKYQRVFLEDLEKMELGPEPSLFKSRHHCIRLHYLV-----------------------NGQGGYFHMFRSTGTRFFNNVAVPINSEEEAIESLKAICESFKVALSVKSLNVPLFEG--KLERRRS 767
BLAST of phosphatidylinositide phosphatase SAC2 vs. TrEMBL
Match: A0A4D9EI43 (Cdc42 effector protein 3 OS=Platysternon megacephalum OX=55544 GN=DR999_PMT07043 PE=4 SV=1) HSP 1 Score: 465.307 bits (1196), Expect = 1.601e-138 Identity = 294/761 (38.63%), Postives = 448/761 (58.87%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINLRSGRNDTE---QKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ G AL+C R G + A ++ WNPVCLG ++G IGK++ D L+LI + +G+ P V +I+KI I L+ +L+++LCK+HHFGI KT++IT D K L+K F + NV + SN K +++ + E+ E++F+ + D FY + D+T+++Q+Q + +N PLWR+ D+RFFWNKHM+Q+ I + + ++ +IPIIQGFVQI+ +N S P P +D H + +V LISRR+R+RAG R++RRGVD+NGNVANYVETEQ + V N H +SF+Q RGSVPVFWSQ +Y+P L++SE+E F HFE +L Y+K V++NLVD E+ I DAYL+ ++ +N+ +T V FDFH++CRG++F+NV L + I DMK+ WVD+ G+IC+Q+ IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP +I Q MWANNGD++SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R R+ RQA IDL+ G + ++ ++ + + E ++ ++ ++ I +L K L +E+ G LI C+ + + +D++ + L++ Y+V+ D + + L L++++KI+IG E +F + + + +R++Y
Sbjct: 1 MELFQAKDHYILQRGERALWCSRRDGTLQLRPATDLLLAWNPVCLGLVEGVIGKVQLHTDLPWWLLLIRQKALIGKLPEGHEVCKITKIAVIPLSETDPQDLELELCKKHHFGINKTEKITQSPDDSKFLLKTFTQIKSNV--------------SASNKKKIKESKEKEKLERRLLEELFKMFMDSDSFYYSL----TYDLTNSVQKQSSCE-KTNLPLWRKVDDRFFWNKHMIQDLINTDNA------------------------------EVDSWVIPIIQGFVQIEELVVNYSDASDDEKSSPETPPQEPVCVDDIHP-QFLVALISRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHN----HTLSFIQTRGSVPVFWSQVGYRYNPRPRLDKSEKETIPYFCAHFEEQLKIYKKQVIINLVDQT--GREKIIGDAYLKQVLLYNNSNLTYVSFDFHEHCRGMKFENVQTLTDAIHDIILDMKWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPMKCNRIYQIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVIDLMQGIPVTEDLYSIFTKEKEHEALHKETLRSHQELISQLLQSYMKLLLPDDEKFHGGWALIDCDPSLIDATHKDVDVLLLLS-NSSYYVA--------YYDDEVDKVNQYQRLSLEALEKIEIGPEPTLFGKPKFSCMRLHY 696
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Cavefish
Match: inpp5f (inositol polyphosphate-5-phosphatase F [Source:NCBI gene;Acc:570007]) HSP 1 Score: 460.299 bits (1183), Expect = 1.294e-139 Identity = 293/761 (38.50%), Postives = 437/761 (57.42%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIG---NESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ +G AL+C R G +S A ++ WNP+CLG ++G IGKI+ AD L+LI + VG P V++I+KI I L+ +L+++LCK+HHFGI KT++IT D K L+K F + NV + PI + + ER +++++ + D FY + D+T+++QRQ S+ S+ PLW++ D+RFFWNKHM+Q+ I + + ++ +IPIIQGFVQ++ +N P+ P +D H V LISRR+R+RAG R++RRGVD G+VANYVETEQ + V + H +SFVQ RGSVPVFWSQ +Y+P LE+ E+E F HFE +L Y+K V++NLVD N E+ I DA+L+ ++ +N+P +T V FDFH++CRG++F+NV L + I DM++ WVD+ G+IC Q IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP Y+I Q MWANNGD +SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R R+ RQA IDL++G E I + + ++ + ++ + L + L +E+ G LI C+ + + +D++ + L++ Y+V+ D + R L L+ ++KI+IG E +F + + +R++Y
Sbjct: 53 MELFQAKDHYILQSGDNALWCSRKDGSLSVRPATDLLLAWNPICLGLVEGVIGKIQLHADFPLGLVLIRQKALVGLLPGDHKVYKITKIAVIPLSDEEPQDLELELCKKHHFGINKTEKITQSPDESKFLLKTFSQIKSNVAV----------PIKKKVKE----NKEKERLEKRLLDELYKIFVDSDSFYY----SPTYDLTNSVQRQGASE-KSDLPLWKQVDDRFFWNKHMIQDLIN------------------------------LQVPQVDFWVIPIIQGFVQVEELVVNYNDSPDEEKSSPDTPPQEHTCVDDIHP-RFTVALISRRSRHRAGMRYKRRGVDTEGHVANYVETEQLIHVHS----HTLSFVQTRGSVPVFWSQVGYRYNPRPRLEKGEKETVPYFSSHFEQQLKIYQKQVIINLVDQN--GREKMIGDAFLKQVLLYNNPNLTYVSFDFHEHCRGMKFENVQTLTDAIADIITDMRWGWVDQAGVICTQDGIFRVNCMDCLDRTNVVQAAIARVVMEKQLKKLGVMPPEQPLPLRCYRIYQVMWANNGDTISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVIDLMMGLPVTEDLYSIFSKEKEHEEKVKQSQRGAQEQVSLLLQTYMQLLLPDDEKFHGGWALIDCDPSLIDATHKDVDVLLLLS-NNAYYVA--------YYDEEADRVNQYQRLSLEGLEKIEIGPEPTLFGKPKYCCMRLHY 748
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Cavefish
Match: inpp5f (inositol polyphosphate-5-phosphatase F [Source:NCBI gene;Acc:570007]) HSP 1 Score: 414.461 bits (1064), Expect = 9.940e-124 Identity = 280/761 (36.79%), Postives = 419/761 (55.06%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIG---NESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF-RLRQNMIRVYY 2298
MELF+ K HYI+ +G AL+C R G +S D L+LI + VG P V++I+KI I L+ +L+++LCK+HHFGI KT++IT D K L+K F + NV + PI ++ + ER +++++ + D FY + D+T+++QRQ S+ S+ PLW++ D+RFFWNKHM+Q+ I + + ++ +IPIIQGFVQ++ +N P+ P +D H V LISRR+R+RAG R++RRGVD G+VANYVETEQ + V + H +SFVQ RGSVPVFWSQ +Y+P LE+ E+E F HFE +L Y+K V++NLVD N E+ I DA+L+ ++ +N+P +T V FDFH++CRG++F+NV L + I DM++ WVD+ G+IC Q IFRVNC+DCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP Y+I Q MWANNGD +SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R R+ RQA IDL++G E I + + ++ + ++ + L + L +E+ G LI C+ + + +D++ + L++ Y+V+ D + R L L+ ++KI+IG E +F + + +R++Y
Sbjct: 1 MELFQAKDHYILQSGDNALWCSRKDGSLSVR---------------------------PDFPLGLVLIRQKALVGLLPGDHKVYKITKIAVIPLSDEEPQDLELELCKKHHFGINKTEKITQSPDESKFLLKTFSQIKSNVAV----------PIKKKV----KENKEKERLEKRLLDELYKIFVDSDSFYYS----PTYDLTNSVQRQGASE-KSDLPLWKQVDDRFFWNKHMIQDLIN------------------------------LQVPQVDFWVIPIIQGFVQVEELVVNYNDSPDEEKSSPDTPPQEHTCVDDIHP-RFTVALISRRSRHRAGMRYKRRGVDTEGHVANYVETEQLIHVHS----HTLSFVQTRGSVPVFWSQVGYRYNPRPRLEKGEKETVPYFSSHFEQQLKIYQKQVIINLVDQN--GREKMIGDAFLKQVLLYNNPNLTYVSFDFHEHCRGMKFENVQTLTDAIADIITDMRWGWVDQAGVICTQDGIFRVNCMDCLDRTNVVQAAIARVVMEKQLKKLGVMPPEQPLPLRCYRIYQVMWANNGDTISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVIDLMMGLPVTEDLYSIFSKEKEHEEKVKQSQRGAQEQVSLLLQTYMQLLLPDDEKFHGGWALIDCDPSLIDATHKDVDVLLLLS-NNAYYVA--------YYDEEADRVNQYQRLSLEGLEKIEIGPEPTLFGKPKYCCMRLHY 669
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Cavefish
Match: sacm1la (SAC1 like phosphatidylinositide phosphatase [Source:NCBI gene;Acc:103032253]) HSP 1 Score: 209.149 bits (531), Expect = 1.535e-56 Identity = 156/448 (34.82%), Postives = 237/448 (52.90%), Query Frame = 1
Query: 607 NGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNN-PLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHP-PIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXX--XXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGN---ESSVE 1920
N D FY C D D+T QR + + L RAD+RF WN ++L++ + L++ P+I GF+ +KP +N K+ +E I LISRR+ RAG R+ RG+D G+ AN+VETEQ ++ N ++ SFVQ RGS+P FWSQ +LKY P P I S + + F++HF++++ Y K V++NLV N + SE + A+ + + + I + FDFH C +++ + IL+ V ++ + Y + G ++ EQ FR NC+DCLDRTNV+Q +LA ++ QL++LG+L + ++F +I ++ WA+N +A ++QY+GT A+K DFTRTG RT GLV DG +SM RYY + RQ +IDL +GN + SVE
Sbjct: 165 NTDGFYFCTDY----DLTHTQQRLANTSPDFQEMSLLERADQRFVWNGYLLRDFFAQPE--------------------------------LQKFAFPVIHGFIAMKP--------CCINGKI-----------FEWI--LISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVQYNNSRA----SFVQTRGSMPFFWSQRPNLKYKPKPQI--SSTTNHLDGFQRHFDSQVLIYGKQVILNLV--NQKGSELPLEQAFAKLVNSMENGMIKYIAFDFHKECSKMRWHRLQILVDAVAEMQDEFGYFMLSSEGRVVSEQSGTFRSNCMDCLDRTNVIQSLLARRSLQNQLQRLGVLHVGQKIEEQADFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQWGLVMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYTVDESVE 547
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Cavefish
Match: sacm1la (SAC1 like phosphatidylinositide phosphatase [Source:NCBI gene;Acc:103032253]) HSP 1 Score: 201.06 bits (510), Expect = 1.374e-54 Identity = 148/450 (32.89%), Postives = 225/450 (50.00%), Query Frame = 1
Query: 607 NGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNN-PLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPV--NIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHP-PIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXX--XXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGN---ESSVE 1920
N D FY C D D+T QR + + L RAD+RF WN ++L++ + L++ P+I GF K L TH P K N + Y + +G +D G+ AN+VETEQ ++ N ++ SFVQ RGS+P FWSQ +LKY P P I S + + F++HF++++ Y K V++NLV N + SE + A+ + + + I + FDFH C +++ + IL+ V ++ + Y + G ++ EQ FR NC+DCLDRTNV+Q +LA ++ QL++LG+L + ++F +I ++ WA+N +A ++QY+GT A+K DFTRTG RT GLV DG +SM RYY + RQ +IDL +GN + SVE
Sbjct: 100 NTDGFYFCTD----YDLTHTQQRLANTSPDFQEMSLLERADQRFVWNGYLLRDFFAQPE--------------------------------LQKFAFPVIHGF------KFCL-THKPTYNKKKFGNY----LITIYSVFLG------------------IDSEGHAANFVETEQIVQYNNSRA----SFVQTRGSMPFFWSQRPNLKYKPKPQI--SSTTNHLDGFQRHFDSQVLIYGKQVILNLV--NQKGSELPLEQAFAKLVNSMENGMIKYIAFDFHKECSKMRWHRLQILVDAVAEMQDEFGYFMLSSEGRVVSEQSGTFRSNCMDCLDRTNVIQSLLARRSLQNQLQRLGVLHVGQKIEEQADFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQWGLVMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYTVDESVE 476
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Cavefish
Match: sacm1lb (phosphatidylinositide phosphatase SAC1-A [Source:NCBI gene;Acc:111190068]) HSP 1 Score: 195.667 bits (496), Expect = 2.558e-52 Identity = 143/443 (32.28%), Postives = 233/443 (52.60%), Query Frame = 1
Query: 613 DCFYLCYDSEKSCDITSNIQR-QKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLI-CEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXX--XXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEI 1923
D FY D D+T +QR S L RAD+RF WN ++L++ + L P++ G++ +K +N K+ + +ISRR+ RAG R+ RG+D G+ AN+VETEQ ++ + K+ SFVQ RGS+P +WSQ +LKY P + +S + + F++HF++++ Y K V++NL+ N + SE+ + A+ + + + + V FDFH C +++ + IL+ V + + Y VD +G + +Q+ FR NC+DCLDRTNVVQ +LA +++QL+++G+L + + ++F +I ++ WA+N +A ++QY+GT A+K DFTRTG RT GL+ DG +SM RYY + RQ +IDL +GN + E+
Sbjct: 128 DGFYFATDY----DLTHTLQRLANTSPEFQEMSLLERADQRFVWNGYLLRDFSTQPE--------------------------------LHRFACPVVHGYITMKS--------CCINGKVFDW-------------NIISRRSCFRAGVRYYVRGIDTEGHAANFVETEQIVQYNSAKA----SFVQTRGSIPFYWSQRPNLKYKPKPQISKSSN-HLDGFQRHFDSQIITYGKQVILNLI--NQKGSEKPLELAFAKMVENLGNGMLKYVAFDFHKECSRMRWHRLQILVDTVADLQEEFGYFLVDADGSVQVQQEGTFRSNCMDCLDRTNVVQSLLARRSLQSQLQRMGVLHVGQRIEDQADFEKIYKNSWADNANACAKQYAGTGALKTDFTRTGKRTQWGLLMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNYAVDEV 506
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Sea Lamprey
Match: inpp5f (inositol polyphosphate-5-phosphatase F [Source:NCBI gene;Acc:570007]) HSP 1 Score: 190.274 bits (482), Expect = 4.254e-52 Identity = 113/280 (40.36%), Postives = 167/280 (59.64%), Query Frame = 1
Query: 1447 RGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIG----NESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF 2265
RG++F+NV IL + +I DMK+ W D GLI Q+ +FRVNC+DCLDRTNVVQ +A +V+E+QL+KLG + PE LP +I Q MWAN+GD +SRQY+GTAA+KGDFTRTG R G++KDG +S +RYYL + R+ RQAAIDL+ G ++ S + R ++ + + + + +L C K L ++EE G LI C+ + + +D++ V LI + Y+V+ +Q + L ++KI+IG E +F
Sbjct: 1 RGMKFENVHILTDAICEIISDMKWCWADAAGLIQVQQGVFRVNCMDCLDRTNVVQAAIARIVMESQLKKLGAMPPEHQLPIKCRRIYQVMWANHGDTVSRQYAGTAALKGDFTRTGERRFAGVMKDGYNSANRYYLNQFRDAYRQAAIDLMQGLPVTDDLSTIVSRERHHEALARRESRRSQAEQVSQLLQSCMKQLLPSHEEFHGGWALIDCDPSLTDATHRDVD-VLLILTNRAYYVAYFDEEADKITHYQR--------IDLADLEKIEIGPEPTLF 271
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Sea Lamprey
Match: synj1 (synaptojanin 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9180]) HSP 1 Score: 119.398 bits (298), Expect = 3.177e-27 Identity = 86/285 (30.18%), Postives = 147/285 (51.58%), Query Frame = 1
Query: 1078 VDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPP-IILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHL-IKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLIC--------EQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLII 1899
D++G VAN+ ETEQ + ++++ + SFVQ+RGSVP+FW Q L+ + + R E N A +HF Y K +VVNL+ + + E ++ A+ H+ ++ I + FD+H +G L G+ R ++++ G C QK R NC+DCLDRTN VQ A +++ QL LG L+ + + + F ++ +++W+ GD +S+ Y+GT A++G +KDG S++R + ++Q A+DL++
Sbjct: 226 ADDSGQVANFCETEQIIFIDDE----VTSFVQLRGSVPLFWEQPGLQVGSHRVKMSRGYEANAPALDRHFAMLKELYGKQMVVNLLGS--KEGEHMLSKAFQSHMQASRHASDIPMLNFDYHLLLKG-SSQRSERLQSGLGNKVR----PFLEQCGFYCFHEGVVSRVQKGTVRTNCLDCLDRTNSVQTHFAVDMLKRQLEDLG-LAEKPQMVARFDEVFRALWSAVGDLVSKMYAGTGALEGKTK----------LKDGARSVTRTIQNNFFDGAKQEAMDLLL 488
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Sea Lamprey
Match: FIG4 (FIG4 phosphoinositide 5-phosphatase [Source:HGNC Symbol;Acc:HGNC:16873]) HSP 1 Score: 49.2914 bits (116), Expect = 5.750e-6 Identity = 35/97 (36.08%), Postives = 53/97 (54.64%), Query Frame = 1
Query: 1078 VDENGNVANYVETEQFLK---VENDKSPHLVSFVQIRGSVPVFWSQ--FSLKYHPPIILERSEEENQEAFKKHFEAELNNY-EKVVVVNLVDTNIER 1350
+ G+VAN VETEQ ++ V S+VQ+RGSVP+ WSQ S+ PPI L++++ A HF+ L + +V++NLV E+
Sbjct: 251 ANSEGDVANEVETEQIVQDASVMTFAHGRFSSYVQLRGSVPLHWSQDISSMIPKPPITLDQADPYMLVA-GLHFDQMLQRFGSPIVILNLVKKRHEK 346
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Yeast
Match: SAC1 (Phosphatidylinositol phosphate (PtdInsP) phosphatase; involved in hydrolysis of PtdIns[4]P in the early and medial Golgi; regulated by interaction with Vps74p; ER localized transmembrane protein which cycles through the Golgi; involved in protein trafficking and processing, secretion, and cell wall maintenance; regulates sphingolipid biosynthesis through the modulation of PtdIns(4)P metabolism [Source:SGD;Acc:S000001695]) HSP 1 Score: 205.682 bits (522), Expect = 2.553e-56 Identity = 153/453 (33.77%), Postives = 236/453 (52.10%), Query Frame = 1
Query: 586 KMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSP--HLVSFVQIRGSVPVFWSQFS-LKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIF---RDMKYSWVDKNG----LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXN--FYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGN 1905
K+ + + FY Y + D+T+++QR ++ ++ W+ ADERFFWN ++ ++ ++ F ++ + P+I G+ + LN +P+ ++GLI+RR+ RAGTR+ RRGVD++GNV N+ ETEQ L EN +S H+ SF+Q RGSVP++W++ + LKY P ++L E + +A KKHF+ + Y +VNLV N + E + + Y + N PKI V FDFH CR +Q+ V +LI + K+ D + +D NG ++ EQ S+ R NC+DCLDRTNVVQ +LA V++ + +++ + N Q++WA+N DA+S YSGT A+K DFTRTG RT G D ++S SRYY + RQ + DL +G
Sbjct: 113 KLLELHLKNSTFYFSY----TYDLTNSLQRNEKVGPAAS---WKTADERFFWNHYLTED---------LRNFAH-------------------QDPRIDSFIQPVIYGYAKTVDAVLNA---TPI------------------VLGLITRRSIFRAGTRYFRRGVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPIYWAEINNLKYKPNLVLG---ENSLDATKKHFDQQKELYGDNYLVNLV--NQKGHELPVKEGYESVVHALNDPKIHYVYFDFHHECRKMQWHRVKLLIDHLEKLGLSNEDFFHKVIDSNGNTVEIVNEQHSVVRTNCMDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAPLLTSYQNLWADNADAVSVAYSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLGG 504
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Yeast
Match: INP52 (Polyphosphatidylinositol phosphatase; dephosphorylates a number of phosphatidylinositol phosphates (PtdInsPs, PIPs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain; INP52 has a paralog, INP53, that arose from the whole genome duplication [Source:SGD;Acc:S000005050]) HSP 1 Score: 154.066 bits (388), Expect = 4.662e-38 Identity = 99/293 (33.79%), Postives = 154/293 (52.56%), Query Frame = 1
Query: 1078 VDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKIT----CVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKY-SWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXN-FYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNESSVEIINL 1932
+D++G+VAN+VETE + S + +F QIRGS+P+FW Q + P I + RS E Q F +HF Y V ++NL+ T + SE +++ Y + L KI FDFH F S +I + D Y S+ K G LI EQ +FR NC+DCLDRTN++Q ++ V + L L+ P + N F Q + ++WA+NGD +S+ Y+GT A+K ++R G + +G + D S+SR Y+ + +Q ID ++G +++ L
Sbjct: 280 IDDDGHVANFVETEMIMY----SSQYCYAFTQIRGSLPIFWEQDTSLISPKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLLST--KSSEIQLSRRYKEQLKNSEKMKIGRDVFLTSFDFHRETSQDGFAAASRIIPKIRNTILDAGYFSYDVKEGRLISEQDGVFRTNCLDCLDRTNLIQQTISLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGDQISQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLLGKLPHQQVVEL 566
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Yeast
Match: INP53 (Polyphosphatidylinositol phosphatase; dephosphorylates multiple phosphatidylinositol phosphates; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains; INP53 has a paralog, INP52, that arose from the whole genome duplication [Source:SGD;Acc:S000005635]) HSP 1 Score: 152.14 bits (383), Expect = 1.522e-37 Identity = 132/441 (29.93%), Postives = 205/441 (46.49%), Query Frame = 1
Query: 607 NGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHL-----IKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGV-TKIFRDMKYSW-VDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXX-XXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIG 1902
NG +Y D+TS +Q + Q++ + + +E + WN ++QE I D L ++ I E L +I+GF + + + ++ + +IS+++ RAGTRF RGVD+ NVAN+VETE + S + +F QIRGS+PVFW Q + +P + + RS E Q F KH + Y V VVNL+ T + SE +++ Y +HL + FN I FDFH F V LI + + YS+ V + I EQ IFR NC+DCLDRTN+ Q +++ T L L+S +F ++WA++GD +S+ Y+GT A+K F+R G ++ G + D S+SR Y+ + +Q ID ++G
Sbjct: 148 NGSFYY-----SSDFDLTSTLQHRGYGQHSLSTDTY---EEEYMWNSFLMQEMITYRDHL---------------------DTNLKQILDDEGFLTTVIRGFAETF---------------------VSYVKKLKVALTIISKQSWKRAGTRFNARGVDDEANVANFVETEFIMY----SSQYCYAFTQIRGSIPVFWEQGTSLINPRVQITRSFEATQPVFDKHIMKSVEKYGPVHVVNLLST--KSSEIELSKRYKEHLTHSKKLNFNK-DIFLTEFDFHKETSQEGFSGVRKLIPLILDSLLSSGYYSYDVREKKNISEQHGIFRTNCLDCLDRTNLAQQIISLAAFRTFLEDFRLISSNSFIDDDDFVSKHNTLWADHGDQISQIYTGTNALKSSFSRKGKMSLAGALSDATKSVSRIYINNFMDKEKQQNIDTLLG 531
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Yeast
Match: FIG4 (Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase; required for efficient mating and response to osmotic shock; physically associates with and regulated by Vac14p; contains a SAC1-like domain; homologous to human FIG4, which is associated with CMT4J, a form of Charcot-Marie-Tooth disorder [Source:SGD;Acc:S000005269]) HSP 1 Score: 78.1814 bits (191), Expect = 7.086e-15 Identity = 83/308 (26.95%), Postives = 137/308 (44.48%), Query Frame = 1
Query: 1078 VDENGNVANYVETEQ---------FLKVEND--KSPHLVSFVQIRGSVPVFWSQFS--LKYHPPIILERSEEENQEAFKKHFEAELNNYE--KVVVVNLVDTNIERSER--KIADAYLQHLIKFNS--PKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICE---------QKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLG-XXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNES 1911
V+ G+VAN VETEQ F + N S SFVQ RGS+P++W+Q + L PPI + + A HF+ Y + ++NL+ T E++ R K+ + Q + N P + + + D R + D +GV + + V G+ Q+ I R NC+DCLDRTN Q ++ + QL+ LG + + S+ I+ ++ + GD ++ QY G+ + T + +D + S+ R+Y + RQ AI+L +G+ S
Sbjct: 280 VNNKGHVANEVETEQIVTDMILTPFHQPGNGFFDSDRYTSFVQHRGSIPLYWTQDASNLTTKPPIRINVVDPFFSPA-ALHFDNLFQRYGGGTIQILNLIKTK-EKTPRETKLLWEFEQCIDYLNEFLPTLKKLDYTSWDMSRASKQDG-----QGVIEFLEKYAVNTVTTTGIFHNGPDFASTKIQEGICRSNCIDCLDRTNAAQFVIGKRALGCQLKSLGIIDNSYLEYDSDIVNILTELFHDLGDTIALQYGGSHLVNTMETYRKINQWSSHSRDMIESIKRFYSNSFVDAQRQDAINLFLGHYS 580
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Yeast
Match: INP51 (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth [Source:SGD;Acc:S000001264]) HSP 1 Score: 65.4698 bits (158), Expect = 4.938e-11 Identity = 58/259 (22.39%), Postives = 114/259 (44.02%), Query Frame = 1
Query: 1078 VDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWS--QFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMK--------YSWVDKNGL-ICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVK 1821
+ E+G V+ +VETE + E + S+ Q+ GS+P+FW + L Y I + + E Q AF +HF+ + Y V +VN++ E S+ K+A Y + + KIT + + + S+L K K+ +K +++ G+ +Q + R++ D +++ N V+ +++ V+E ++ + F +W+ N L R Y+ G +T+ ++ V+
Sbjct: 265 ISEDGRVSLFVETEIVVTTEK----FIFSYTQVNGSIPLFWESVESQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPKSE-SQEKLALTY-KDCAESKGIKITNIEY------------SSSVLTKSPHKLLYLLKQDIYEFGAFAYDISRGIYFAKQTGVLRISAFDSIEKPNTVERLVSKEVLELTTNEIDVFELTSP----FLDAHDKLWSENYYWLDRTYTKHTKNSGKYTKVYSKLFGSRVR 501
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Nematostella
Match: EDO43250 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZB6]) HSP 1 Score: 427.172 bits (1097), Expect = 2.056e-128 Identity = 274/707 (38.76%), Postives = 410/707 (57.99%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQI----KPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGN----ESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVS 2145
MEL++ + ++II + +L+C+R G + + ++PVC G + G IGKI+F G+ KL++I + +G P V+R+ ++ + L+ V L++D C++H G + R T+GQ+ K FQ+ K++ I + + + + R+R++ ERR++EE KMF ++ D FY + DIT+ +QRQ Y+ + PLW+R D+RFFWN HML + I + D L ++P+IQG+ I F+ + +I++ LP E++++ LISRR+ RAGTR++RRGVD++G VANYVETEQ ++ E H VSFVQ+RGSVPVFWSQ KY PP L++ E + Q AF+ HF +L+ Y VVVVNLVD E+ I+D +++H++ +N P +T + FDFH+YCRG++F+NVS+L+ + + +DM+Y W D G+ICEQ+S+FRVNC+DCLDRTNVVQ LA ++E QLRKLG L P+++LP++ + MWANNGDA+SRQY+GTAA+KGDFTRTG R GL+KDG +S +RYYL R + RQ ID+++GN + S I LRS + EQ + ++ED E A Q + L + + E E QD + + L+T Y S
Sbjct: 1 MELYQARDNFIIKDAYFSLWCNRSDGGLVPRQGVHPNEAFDPVCKGIVYGVIGKIQFFPGGDWKLLVITKRTLLGLFPGNHEVYRVDRVAYLPLSPGDVPELELDPCEKHQSGGRGIKR---DTEGQQ---KSFQQTWKSIKTAATNIKENVKSTSTTKEPKDRERDKLERRLVEELLKMFNDS---DSFYYS----PTGDITNTLQRQCGDHYDHSLPLWKRVDKRFFWNSHMLHDLINNEDPLA------------------------------SSWILPVIQGYCSIVHCHNMFEED-DMEEQSDIQIGALP----PEEFDLL--LISRRSIFRAGTRYKRRGVDDDGEVANYVETEQIVRTEI----HSVSFVQVRGSVPVFWSQPGYKYRPPPRLDKDEMDTQAAFRHHFSHQLSLYGGVVVVNLVDQTGR--EKIISDVFMRHILAYNCPLLTYITFDFHEYCRGMKFENVSVLVDSIGDVIKDMRYCWTDPKGIICEQRSVFRVNCMDCLDRTNVVQAALARHLLEMQLRKLGKLMPDQTLPASIRAPFKEMWANNGDAISRQYAGTAALKGDFTRTGERKFTGLMKDGYNSANRYYLNRFKAAYRQTLIDMMLGNPPTEDLSALIDALRSDGQEEEQWTM-EREDPEGESATQDQDVILLLTY----HAYYVASPEGESATQDQDVILLLTYHAYYVAS 646
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Nematostella
Match: EDO36706 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHY2]) HSP 1 Score: 173.711 bits (439), Expect = 2.077e-45 Identity = 146/450 (32.44%), Postives = 232/450 (51.56%), Query Frame = 1
Query: 589 MFQENENGDCFYLCYDSEKSC--DITSNIQR-QKQSQYNSNNPLWRRADERFFWNKHMLQE-AIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHP-PIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSP--KITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLI-CEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXX--NFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGN 1905
M Q + FY SC D+T +QR + S PL+ R D RF WN H+L A++ L+ ++P++ GF+ I + +IK + ++ I LISRR+ RAG R+ RG+D GN ANYVETEQ ++ S SFVQIRGS+P++W+Q +LKY P P + S ++ F+ H + E+ +Y+++V++NL+D ++ K+ +I+ NSP + + FDFH C +++D +++LI ++ + Y + K+ I EQK +FR NC+D LDRTNVVQ MLA ++ QL + G+L+ E + +F +++WA+N DA S QY+GT A+K DFTR + G ++DG++S+ ++ + S Q +IDL +GN
Sbjct: 123 MVQSVLQTESFYF------SCTYDLTHTLQRLSRTSPEFLQMPLYERVDPRFVWNSHLLTPFAVQP---------------------------------ELQRFILPVMHGFISI----------TSCSIK---------QRSFDFI--LISRRSCFRAGVRYFMRGLDGEGNAANYVETEQIIQFNTGTS----SFVQIRGSIPLYWTQRPNLKYKPKPQV--NSSADHSLGFQYHIDNEIAHYKELVLINLID---QKGPEKVLGDRFSTIIR-NSPYKETSYEAFDFHKECSKMRWDRLNLLIDRLSPDQKKFGYFSMGKDKDIQSEQKGVFRTNCIDSLDRTNVVQSMLARNSLQLQLEEYGVLATGERIVDHNDFEYTFKNVWADNADACSVQYAGTGALKTDFTR--QEVLFGAMRDGVNSIVTCFIHIF-FSMQDSIDLFLGN 499
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Nematostella
Match: EDO33968 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQQ5]) HSP 1 Score: 130.954 bits (328), Expect = 2.080e-30 Identity = 91/280 (32.50%), Postives = 142/280 (50.71%), Query Frame = 1
Query: 1078 VDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHP-PIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIK-FNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLR-LREMSRQAAID-LIIGN 1905
D++G+VAN+VETEQ + +++ + SFVQ RGSVPVFW Q ++ + L R E AF +H + Y V +VNL+ ++ E ++ + L + + + FD+H C+G + + ++F + L QK + R NC+DC+DRTN +Q + ++ QL+ LG L + SL F + SMW+ NGD +SR Y GT A+ G AR + L +DG S+ R + S+Q AID L++GN
Sbjct: 221 TDDDGHVANFVETEQMIALDD----MITSFVQTRGSVPVFWEQPGIQVGSHKVKLSRGFEAASAAFDRHLTTQKGLYGDVCIVNLL--GMKEGENALSRIFQDELTESIHGHDTPMICFDYHRNCKGGRTSKLKDFADKARQLFNSNSLFFSKGGKLEKRQKGVMRSNCLDCIDRTNNMQTFIGLEMLLVQLQCLG-LGSKASLVPRFQEAFTSMWSQNGDHISRIYIGTGALDGK-----ARVASKL-RDGARSVKRTIRSNFLDGSKQEAIDLLLLGN 487
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Nematostella
Match: EDO26798 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TB19]) HSP 1 Score: 73.9442 bits (180), Expect = 4.883e-15 Identity = 68/193 (35.23%), Postives = 97/193 (50.26%), Query Frame = 1
Query: 586 KMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQI----KPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSP 1152
KMF ++ D FY + DIT+ +QRQ Y+ + PLW+R D+RFFWN HMLQ+ I + D L ++P+IQG+ I F+ + +I++ LP E++++ LISRR+ RAGTR++RRGVD++G VANYVETEQ E D P
Sbjct: 4 KMFNDS---DSFYY----SPTGDITNTLQRQCGDHYDHSLPLWKRVDKRFFWNSHMLQDLINNDDPL------------------------------ASSWILPVIQGYCSIVHCHNMFEED-DMEEQSDIQIGALP----PEEFDLL--LISRRSIFRAGTRYKRRGVDDDGEVANYVETEQSRGRERDPGP 152
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Nematostella
Match: EDO26609 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TBJ8]) HSP 1 Score: 64.3142 bits (155), Expect = 1.870e-12 Identity = 34/85 (40.00%), Postives = 50/85 (58.82%), Query Frame = 1
Query: 1081 DENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHP-PIILERSEEENQEAFKKHFEAELNNYEKVVVVNLV 1332
D++G+VAN+VETEQ + +++ + SFVQ RGSVPVFW Q ++ + L R E AF +H + Y V +VNL+
Sbjct: 8 DDDGHVANFVETEQMIALDD----MITSFVQTRGSVPVFWEQPGIQVGSHKVKLSRGFEAASAAFDRHLTTQKGLYGDVCIVNLL 88
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Medaka
Match: inpp5f (inositol polyphosphate-5-phosphatase F [Source:NCBI gene;Acc:101155539]) HSP 1 Score: 442.965 bits (1138), Expect = 8.371e-134 Identity = 293/749 (39.12%), Postives = 443/749 (59.15%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIG---NESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF 2265
MELF+ K YI+ +G AL+C R G ++ A ++ WNPVCLG ++G +GKI+ D L+LI + VG P V++I+KI I L+ L+++LCK+HHFGI K +++ + K L+K F + NV +P K + K+ +++ER ERR+LEE K+F ++ D FY + D+T+++QRQ S S PLW++ D+RFFWNKHM+Q+ I+ + + + + PIIQGFVQ++ +N S P P +D H V LISRR+R+RAG R++RRGVD +G+VANYVETEQ + V + H +SFVQ RGSVPVFWSQ +Y+P +E+ E+E F HFE +L Y+K V++NL+D + E+ I DA+L+ ++ +N+P +T V FDFH++CRG++F+NV L ++ I DMK++WVD+ G+IC+Q+ FRVNCVDCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP Y+I Q MWANNGD +SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R R+ RQA IDL++G E I + + E++ + ++ + L + L +E+ G LI C+ + + +D++ + L++ +K Y+++ +++D Q +R L L+ ++KI+IG E +F
Sbjct: 1 MELFQAKDEYILQSGDRALWCSRKDGSVTLRAATDLLLAWNPVCLGLVEGIVGKIQLHTDLPLGLVLIRQKALVGHLPGNHKVYKITKIAVIPLSDEEPLELELELCKKHHFGIDKPEKLVQSPEDSKFLIKTFSQIKSNV-----AVPIKKKYPPAFQAKENKEKERLERRLLEELYKIFMDS---DSFYYSL----TYDLTNSVQRQGDSD-RSGLPLWKQVDDRFFWNKHMIQDVID------------------------------LQVPEADLWVTPIIQGFVQVEELVVNYNETSDEERSSPESPPKEITCVDDIHP-RFTVALISRRSRHRAGMRYKRRGVDTDGHVANYVETEQLIHVHS----HTLSFVQTRGSVPVFWSQAGYRYNPRPRIEKGEKETMPFFAAHFEEQLRLYKKQVIINLIDQS--GREKIIGDAFLKQVLLYNNPNLTYVSFDFHEHCRGMKFENVQTLTDAISDIITDMKWAWVDQAGVICKQEGFFRVNCVDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPLKCYRIYQVMWANNGDTISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVIDLMMGVPVTEDLYSIFSKEKEHEEKEKESQRGAQEQVSLLLQTYMQLLLPDDEQFHGGWALIGCDMSLMDANSKDVDVLLLLS-DKAYYIA-YYDEEADKVD-QYQR------LNLEGLEKIEIGPEPTLF 690
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Medaka
Match: inpp5f (inositol polyphosphate-5-phosphatase F [Source:NCBI gene;Acc:101155539]) HSP 1 Score: 407.912 bits (1047), Expect = 2.488e-121 Identity = 283/749 (37.78%), Postives = 425/749 (56.74%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQ-----IDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIG---NESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNEN--EKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIF 2265
MELF+ K YI+ +G AL+C R G ++ A ++ WNPVCLG ++G +GKI+ D L+LI + VG P V++I+KI I L+ L+++LCK+HHFGI K +++ + K L+K F + NV + PI + +++ER ERR+LEE K+F ++ D FY + D+T+++QRQ S S PLW++ E W + PIIQGFVQ++ +N S P P +D H V LISRR+R+RAG R++RRGVD +G+VANYVETEQ + V + H +SFVQ RGSVPVFWSQ +Y+P +E+ E+E F HFE +L Y+K V++NL+D + E+ I DA+L+ ++ +N+P +T V FDFH++CRG++F+NV L ++ I DMK++WVD+ G+IC+Q+ FRVNCVDCLDRTNVVQ +A VV+E QL+KLG++ PE+ LP Y+I Q MWANNGD +SRQY+GTAA+KGDFTRTG R + G++KDG++S +RYYL R R+ RQA IDL++G E I + + E++ + ++ + L + L +E+ G LI C+ + + +D++ + L++ +K Y+++ +++D Q +R L L+ ++KI+IG E +F
Sbjct: 1 MELFQAKDEYILQSGDRALWCSRKDGSVTLRAATDLLLAWNPVCLGLVEGIVGKIQLHTDLPLGLVLIRQKALVGHLPGNHKVYKITKIAVIPLSDEEPLELELELCKKHHFGIDKPEKLVQSPEDSKFLIKTFSQIKSNVAV----------PIKKKAKE-NKEKERLERRLLEELYKIFMDS---DSFYYSL----TYDLTNSVQRQGDSD-RSGLPLWKQVPEADLW-------------------------------------------------VTPIIQGFVQVEELVVNYNETSDEERSSPESPPKEITCVDDIHP-RFTVALISRRSRHRAGMRYKRRGVDTDGHVANYVETEQLIHVHS----HTLSFVQTRGSVPVFWSQAGYRYNPRPRIEKGEKETMPFFAAHFEEQLRLYKKQVIINLIDQS--GREKIIGDAFLKQVLLYNNPNLTYVSFDFHEHCRGMKFENVQTLTDAISDIITDMKWAWVDQAGVICKQEGFFRVNCVDCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPLKCYRIYQVMWANNGDTISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVIDLMMGVPVTEDLYSIFSKEKEHEEKEKESQRGAQEQVSLLLQTYMQLLLPDDEQFHGGWALIGCDMSLMDANSKDVDVLLLLS-DKAYYIA-YYDEEADKVD-QYQR------LNLEGLEKIEIGPEPTLF 665
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Medaka
Match: sacm1la (phosphatidylinositide phosphatase SAC1-B [Source:NCBI gene;Acc:101170855]) HSP 1 Score: 213.001 bits (541), Expect = 3.699e-58 Identity = 149/439 (33.94%), Postives = 232/439 (52.85%), Query Frame = 1
Query: 613 DCFYLCYDSEKSCDITSNIQRQKQSQYNSNN-PLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGL-ICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGX--XXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGNES 1911
D FY C D D+T +QR + + L RAD+RF WN ++L+E + L +P++ GF+ +KP ++N +E I LISRR+ RAG R+ RG+D G+ AN+VETEQ + E K+ SFVQ RGS+P +WSQ +LKY P I+ ++ + + F++HF+++L Y K V+NLV N + SE+ + +A+ + + +S I + FDFH C +++D + IL+ V + + Y V+ +G + Q +FR NC+DCLDRTNV+Q +LA +++QL+++G+ + + F + ++ WA+N +A + QY+GT A+K DFTRTG RT GL+ DG +SM RYY + RQ +IDL +GN S
Sbjct: 128 DGFYFCTD----FDLTHTLQRLANTSPDFQEMSLLERADQRFVWNGNLLRELAGQPE--------------------------------LHRFALPVVHGFIILKPCRINGKI-------------------FEWI--LISRRSCFRAGVRYYVRGIDSEGHAANFVETEQIVLYEGAKA----SFVQTRGSMPFYWSQRPNLKYKPKPIISKTSN-HMDGFQRHFDSQLLIYGKQTVLNLV--NQKGSEKPLEEAFAKMVAGMSSGLINYIAFDFHKECSHMRWDRLQILVDTVAETQEEYSYFMVNSDGKELTHQSGVFRSNCMDCLDRTNVIQSLLARRSLQSQLQRMGILNVGQRIEEQAEFEKTYKNAWADNANACAVQYAGTGALKTDFTRTGKRTKWGLLMDGWNSMIRYYKNNFSDGFRQDSIDLFLGNFS 502
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Medaka
Match: sacm1lb (phosphatidylinositide phosphatase SAC1-A [Source:NCBI gene;Acc:101167819]) HSP 1 Score: 205.297 bits (521), Expect = 1.536e-55 Identity = 146/437 (33.41%), Postives = 233/437 (53.32%), Query Frame = 1
Query: 613 DCFYLCYDSEKSCDITSNIQRQKQSQYN-SNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXX--XXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGN 1905
D FY + D+T +QR + + + L RAD+RF WN H+L+E + + L + ++P+I GF+ IK S +N K K E+ +ISRR+ RAG R+ RG+D +G+ AN+VETEQ ++ K+ SFVQ RGS+P FWSQ +LKY P + ++ + + ++HF++++ Y + VV+NL++ N SE+ + A+ + + + V FDFH C +++ + IL+ V + ++ + VD +G ++ Q FR NC+DCLDRTNV+Q +LA ++ QL+++G+L + L +F + ++ WA+N DA ++QY+GT A+K DFTRTG RT GL+ DG +SM RYY + RQ +IDL +GN
Sbjct: 128 DAFYFA----TTYDLTHTLQRLANTSPDFQDTSLLERADQRFVWNGHLLREFMSQPE--------------------------------LHKFVVPVIHGFISIKS--------SCINGK---------KFEWS----IISRRSCFRAGVRYYVRGIDVDGHAANFVETEQIVQYGGSKA----SFVQTRGSIPFFWSQRPNLKYKPKPQISKAGN-HLDGLQRHFDSQVLLYGRQVVLNLINQN--GSEKPLELAFRNLVTSLGTGMVRYVAFDFHKECSRMRWHRLQILLDMVAEAQEELGFFLVDSDGKVLLSQDGTFRSNCMDCLDRTNVIQSLLARNSLQAQLQRMGVLHLGQKLEEQLDFEKTFKNAWADNADACAKQYAGTGALKTDFTRTGKRTQLGLLMDGWNSMIRYYKNNFSDGFRQDSIDLFLGN 500
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Medaka
Match: sacm1lb (phosphatidylinositide phosphatase SAC1-A [Source:NCBI gene;Acc:101167819]) HSP 1 Score: 183.341 bits (464), Expect = 1.765e-48 Identity = 107/281 (38.08%), Postives = 171/281 (60.85%), Query Frame = 1
Query: 1078 VDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQF-SLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNG-LICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXX--XXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYL-RLREMSRQAAIDLIIGN 1905
+D +G+ AN+VETEQ ++ K+ SFVQ RGS+P FWSQ +LKY P + ++ + + ++HF++++ Y + VV+NL++ N SE+ + A+ + + + V FDFH C +++ + IL+ V + D + VD +G ++ Q FR NC+DCLDRTNV+Q +LA ++ QL+++G+L + L +F + ++ WA+N DA ++QY+GT A+K DFTRTG RT GL+ DG +SM RYY + RQ +IDL +GN
Sbjct: 195 IDVDGHAANFVETEQIVQYGGSKA----SFVQTRGSIPFFWSQRPNLKYKPKPQISKAGN-HLDGLQRHFDSQVLLYGRQVVLNLINQN--GSEKPLELAFRNLVTSLGTGMVRYVAFDFHKECSRMRWHRLQILLDMVAEAQED--FFLVDSDGKVLLSQDGTFRSNCMDCLDRTNVIQSLLARNSLQAQLQRMGVLHLGQKLEEQLDFEKTFKNAWADNADACAKQYAGTGALKTDFTRTGKRTQLGLLMDGWNSMIRYYKNNFSDGFRQDSIDLFLGN 466
BLAST of phosphatidylinositide phosphatase SAC2 vs. Planmine SMEST
Match: SMESG000079090.1 (SMESG000079090.1) HSP 1 Score: 2407.1 bits (6237), Expect = 0.000e+0 Identity = 1287/1293 (99.54%), Postives = 1290/1293 (99.77%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIFRLRQNMIRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAAAKVTNPNVIFDETLQKFEKSKSNPIPSQWLFSINTNTLYENVXXXXXXXXXXXXXXXXXXXXEEQCDTLESYEHLSIDDYPQGNISSEKEDLKVMSNIEFIKKSFFRVKDKVKDRYSIFQSRNTPIIKFPRIRDAKMQGNEELEDHAVKNNGILRKCSLDVRLQGNIEMHQILHSNENQDKKFLTAARSRLGSSSDDESTRRPRNQNFNVKIKKSKSGFLNSASEYMSTLDDLDNDQSSNEDDGCDIFFRXXXXXXXXXXXXXXXKRFAICKDGFKMHIQKKSPLTRFYSSETELGRLDKRSXXXXXXXXXXXXXXXNCGIISNTKFNFKKSPPFIPYGTTQLAAITGGVYQRRAERISLQLSVDETLIEPKNLSSLMRSPNLSNRQKFQHSPPKSFKEPIVSECNNDTQTNEAISEIRNSLINHVQMPMVEVRSPKARERLTKKQIDYATFIEESRKKILGISQPLVTGMIIF 3930
MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVRDRERFERRMLEEFEKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYN+NNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFQEENNLSESENQSSQIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISRRNRNRAGTRFRRRGVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGLLSPEESLPSNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIFRLRQNMIRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAAAKVTNPNVIFDETLQKFEKSKSNPIPSQWLFSINTNTLYENVILSSSLSNLNDDDDDDILNLEEQCDTLESYEHLSIDDYPQGNISSEKEDLKVMSNIEFIKKSFFRVKDKVKDRYSIFQSRNTPIIK PRIRDAKMQGNEELEDHAVKNNGILRKCSLDVRLQGNIEMHQILHSNE+QDKKFLTAARSRLGSSSDDESTRRPRNQNFNVKIKKSKSGFLNSASEYMSTLDDLDNDQSSNEDDGCDIFFRNNCILSNISQSNNQSKRFAICKDGFK+HIQKKSPLTRFYSSETELGRLDKRSQIIDKI QIDDIILQNCGIISNTKFNFKKSPPFIPYGTTQLAAITGGVYQRRAERISLQLSVDETLIEPKNL SLMRSPNLSNRQKFQHSPPKSFKEPIVSECNNDTQTNEAISEIRNSLINHVQMPMVEVRSPKARERLTKKQIDYATFIEESRKKILGISQPLVTGMIIF
Sbjct: 1 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVRDRERFERRMLEEFEKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNANNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFQEENNLSESENQSSQIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISRRNRNRAGTRFRRRGVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGLLSPEESLPSNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIFRLRQNMIRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAAAKVTNPNVIFDETLQKFEKSKSNPIPSQWLFSINTNTLYENVILSSSLSNLNDDDDDDILNLEEQCDTLESYEHLSIDDYPQGNISSEKEDLKVMSNIEFIKKSFFRVKDKVKDRYSIFQSRNTPIIKCPRIRDAKMQGNEELEDHAVKNNGILRKCSLDVRLQGNIEMHQILHSNESQDKKFLTAARSRLGSSSDDESTRRPRNQNFNVKIKKSKSGFLNSASEYMSTLDDLDNDQSSNEDDGCDIFFRNNCILSNISQSNNQSKRFAICKDGFKVHIQKKSPLTRFYSSETELGRLDKRSQIIDKIFQIDDIILQNCGIISNTKFNFKKSPPFIPYGTTQLAAITGGVYQRRAERISLQLSVDETLIEPKNLISLMRSPNLSNRQKFQHSPPKSFKEPIVSECNNDTQTNEAISEIRNSLINHVQMPMVEVRSPKARERLTKKQIDYATFIEESRKKILGISQPLVTGMIIF 1293
BLAST of phosphatidylinositide phosphatase SAC2 vs. Planmine SMEST
Match: SMESG000079090.1 (SMESG000079090.1) HSP 1 Score: 2368.96 bits (6138), Expect = 0.000e+0 Identity = 1274/1293 (98.53%), Postives = 1277/1293 (98.76%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIFRLRQNMIRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAAAKVTNPNVIFDETLQKFEKSKSNPIPSQWLFSINTNTLYENVXXXXXXXXXXXXXXXXXXXXEEQCDTLESYEHLSIDDYPQGNISSEKEDLKVMSNIEFIKKSFFRVKDKVKDRYSIFQSRNTPIIKFPRIRDAKMQGNEELEDHAVKNNGILRKCSLDVRLQGNIEMHQILHSNENQDKKFLTAARSRLGSSSDDESTRRPRNQNFNVKIKKSKSGFLNSASEYMSTLDDLDNDQSSNEDDGCDIFFRXXXXXXXXXXXXXXXKRFAICKDGFKMHIQKKSPLTRFYSSETELGRLDKRSXXXXXXXXXXXXXXXNCGIISNTKFNFKKSPPFIPYGTTQLAAITGGVYQRRAERISLQLSVDETLIEPKNLSSLMRSPNLSNRQKFQHSPPKSFKEPIVSECNNDTQTNEAISEIRNSLINHVQMPMVEVRSPKARERLTKKQIDYATFIEESRKKILGISQPLVTGMIIF 3930
MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKR KDVRDRERFERRMLEEFEKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYN+NNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFQEENNLSESENQSSQIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISRRNRNRAGTRFRRRGVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGLLSPEESLPSNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIFRLRQNMIRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAAAKVTNPNVIFDETLQKFEKSKSNPIPSQWLFSINTNTLYENVILSSSLSNLNDDDDDDILNLEEQCDTLESYEHLSIDDYPQGNISSEKEDLKVMSNIEFIKKSFFRVKDKVKDRYSIFQSRNTPIIK PRIRDAKMQGNEELEDHAVKNNGILRKCSLDVRLQGNIEMHQILHSNE+QDKKFLTAARSRLGSSSDDESTRRPRNQNFNVKIKKSKSGFLNSASEYMSTLDDLDNDQSSNEDDGCDIFFRNNCILSNISQSNNQSKRFAICKDGFK+HIQKKSPLTRFYSSETELGRLDKRSQIIDKI QIDDIILQNCGIISNTKFNFKKSPPFIPYGTTQLAAITGGVYQRRAERISLQLSVDETLIEPKNL SLMRSPNLSNRQKFQHSPPKSFKEPIVSECNNDTQTNEAISEIRNSLINHVQMPMVEVRSPKARERLTKKQIDYATFIEESRKKILGISQPLVTGMIIF
Sbjct: 1 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKR-------------KDVRDRERFERRMLEEFEKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNANNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFQEENNLSESENQSSQIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISRRNRNRAGTRFRRRGVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGLLSPEESLPSNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNRIDFQTKRPPLAIALPLQSIKKIQIGYELNIFRLRQNMIRVYYDLPCSPVDNDKIKIGRIVEKPHQPDNEISNCFFAFKQPSLRLFNNILIDVKCNNDHLESLKAIAESFYAAAKVTNPNVIFDETLQKFEKSKSNPIPSQWLFSINTNTLYENVILSSSLSNLNDDDDDDILNLEEQCDTLESYEHLSIDDYPQGNISSEKEDLKVMSNIEFIKKSFFRVKDKVKDRYSIFQSRNTPIIKCPRIRDAKMQGNEELEDHAVKNNGILRKCSLDVRLQGNIEMHQILHSNESQDKKFLTAARSRLGSSSDDESTRRPRNQNFNVKIKKSKSGFLNSASEYMSTLDDLDNDQSSNEDDGCDIFFRNNCILSNISQSNNQSKRFAICKDGFKVHIQKKSPLTRFYSSETELGRLDKRSQIIDKIFQIDDIILQNCGIISNTKFNFKKSPPFIPYGTTQLAAITGGVYQRRAERISLQLSVDETLIEPKNLISLMRSPNLSNRQKFQHSPPKSFKEPIVSECNNDTQTNEAISEIRNSLINHVQMPMVEVRSPKARERLTKKQIDYATFIEESRKKILGISQPLVTGMIIF 1280
BLAST of phosphatidylinositide phosphatase SAC2 vs. Planmine SMEST
Match: SMESG000079090.1 (SMESG000079090.1) HSP 1 Score: 1296.95 bits (3355), Expect = 0.000e+0 Identity = 693/707 (98.02%), Postives = 694/707 (98.16%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNR 2172
MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKR KDVRDRERFERRMLEEFEKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYN+NNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFQEENNLSESENQSSQIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISRRNRNRAGTRFRRRGVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGLLSPEESLPSNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNR
Sbjct: 1 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKR-------------KDVRDRERFERRMLEEFEKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNANNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFQEENNLSESENQSSQIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISRRNRNRAGTRFRRRGVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGLLSPEESLPSNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENEKEFQDMNTVSLITLEKIYFVSNLLSLPRNR 694
BLAST of phosphatidylinositide phosphatase SAC2 vs. Planmine SMEST
Match: SMESG000079090.1 (SMESG000079090.1) HSP 1 Score: 1234.17 bits (3192), Expect = 0.000e+0 Identity = 660/677 (97.49%), Postives = 664/677 (98.08%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENE 2082
MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKR KDVRDRERFERRMLEEFEKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYN+NNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFQEENNLSESENQSSQIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISRRNRNRAGTRFRRRGVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGLLSPEESLPSNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCN+++
Sbjct: 1 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKR-------------KDVRDRERFERRMLEEFEKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNANNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFQEENNLSESENQSSQIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISRRNRNRAGTRFRRRGVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGLLSPEESLPSNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNDSD 664
BLAST of phosphatidylinositide phosphatase SAC2 vs. Planmine SMEST
Match: SMESG000079090.1 (SMESG000079090.1) HSP 1 Score: 1231.85 bits (3186), Expect = 0.000e+0 Identity = 660/677 (97.49%), Postives = 664/677 (98.08%), Query Frame = 1
Query: 52 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKRIPWKSEPITLSNDKDVXXXXXXXXXXXXXXXKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNSNNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFXXXXXXXXXXXXXXXIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISXXXXXXXXXXXXXXXVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGXXXXXXXXXXNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNENE 2082
MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKR KDVRDRERFERRMLEEFEKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYN+NNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFQEENNLSESENQSSQIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISRRNRNRAGTRFRRRGVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGLLSPEESLPSNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCN+++
Sbjct: 1 MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGFIGKIKFSADGESKLMLINRIEKVGESPIFGSVWRISKITTISLNALPVSNLDIDLCKRHHFGIKKTDRITTPTDGQKSLMKGFQEHMKNVNIKPKR-------------KDVRDRERFERRMLEEFEKMFQENENGDCFYLCYDSEKSCDITSNIQRQKQSQYNANNPLWRRADERFFWNKHMLQEAIESADRLLMKTFGRYIFQEENNLSESENQSSQIMIRHLEEILIPIIQGFVQIKPFKLNLPTHSPVNIKLPNLPQIDMKHEYEMIVGLISRRNRNRAGTRFRRRGVDENGNVANYVETEQFLKVENDKSPHLVSFVQIRGSVPVFWSQFSLKYHPPIILERSEEENQEAFKKHFEAELNNYEKVVVVNLVDTNIERSERKIADAYLQHLIKFNSPKITCVMFDFHDYCRGLQFDNVSILIKGVTKIFRDMKYSWVDKNGLICEQKSIFRVNCVDCLDRTNVVQCMLAGVVIETQLRKLGLLSPEESLPSNFYQIMQSMWANNGDALSRQYSGTAAMKGDFTRTGARTMNGLVKDGMSSMSRYYLRLREMSRQAAIDLIIGNESSVEIINLRSGRNDTEQKLIKQKEDNIKELANQCKKACLKTNEECLGESILIFCNDSD 664 The following BLAST results are available for this feature:
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of phosphatidylinositide phosphatase SAC2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30022796 ID=SMED30022796|Name=phosphatidylinositide phosphatase SAC2|organism=Schmidtea mediterranea sexual|type=transcript|length=4345bpback to top protein sequence of SMED30022796-orf-1 >SMED30022796-orf-1 ID=SMED30022796-orf-1|Name=SMED30022796-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1294bp MELFETKKHYIIINGTVALFCDRLSGYISFSDANEVSYEWNPVCLGTIKGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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