dual specificity protein phosphatase 12

Overview


Name	dual specificity protein phosphatase 12
Smed ID	SMED30022703
Length (bp)	1254

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of dual specificity protein phosphatase 12 (SMED30022703) t-SNE clustered cells

Violin plots show distribution of expression levels for dual specificity protein phosphatase 12 (SMED30022703) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of dual specificity protein phosphatase 12 (SMED30022703) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for dual specificity protein phosphatase 12 (SMED30022703) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30022703

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
gut	SMED30022703	SMESG000014789.1	Contig1758	GPL15192	PMID:23079596 Forsthoefel et al., 2012
epidermis	SMED30022703	SMESG000014789.1	Contig1758	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30022703	SMESG000014789.1	Contig1758	GPL15192	PMID:23079596 Forsthoefel et al., 2012
head region	SMED30022703	SMESG000014789.1	OX_Smed_1.0.02479	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Human
Match: DUSP12 (dual specificity phosphatase 12 [Source:HGNC Symbol;Acc:HGNC:3067])

HSP 1 Score: 152.91 bits (385), Expect = 3.955e-42
Identity = 102/297 (34.34%), Postives = 151/297 (50.84%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTV-MDSPLLHK---MEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQF-----NLSKSSTDLIQFKCKKCRFLLFDNSSVVEHSKMK-----ASKTITENTICNE-------EIFIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVK 894
             L+ G     +  D L+   I  +LTV  + P       +ED    F+ A D P  DL+S+ D    FI   R  G  VL+HC AG+SRS  I+TA++MK  ++    A EK++  K     N+GF  QLK+Y  M    D  S  YKQ+ RL    +       + Q  F      +S+   D + +KC+KCR  LF +SS+++H +       A K +T +++            FIE + W++S+      G++ CPKC+ KLGS+ W GE+C CG W+ PAF I K +VD +K
Sbjct:   33 GLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYKQY-RLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHREGSGPIAFAHKRMTPSSMLTTGRQAQCTSYFIEPVQWMESALLGVMDGQLLCPKCSAKLGSFNWYGEQCSCGRWITPAFQIHKNRVDEMK 328

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Human
Match: DUSP19 (dual specificity phosphatase 19 [Source:HGNC Symbol;Acc:HGNC:18894])

HSP 1 Score: 92.4337 bits (228), Expect = 5.192e-21
Identity = 51/128 (39.84%), Postives = 73/128 (57.03%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENG-RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQLKIY 459
            L LGS + A ++D LK  ++ +IL V        + DF YK I   D+P  +++SYF E  EFIE   RK G VL+HC AG+SR+  I+  ++M   +     A   +K  +  ICPN GFM+QL+ Y
Sbjct:   73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTY 200

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Human
Match: DUSP6 (dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072])

HSP 1 Score: 91.2781 bits (225), Expect = 2.912e-20
Identity = 57/127 (44.88%), Postives = 78/127 (61.42%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDS-P-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            L+LG  +D++N+D+L+   IKYIL V  + P L     +F YK I   D  +Q+L  +F E   FI+  R K  GVL+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:   89 LYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 215

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Human
Match: DUSP9 (dual specificity phosphatase 9 [Source:HGNC Symbol;Acc:HGNC:3076])

HSP 1 Score: 92.8189 bits (229), Expect = 4.851e-20
Identity = 57/128 (44.53%), Postives = 78/128 (60.94%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDS-P-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            NL+LGS  D++N++ L  L I+YIL V  + P    K  DF+YK I   D  +Q+L  +F E  EFI+       GVL+HCLAG+SRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  210 NLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQL 337

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Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDS-P-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            NL+LGS  D++N++ L  L I+YIL V  + P    K  DF+YK I   D  +Q+L  +F E  EFI+       GVL+HCLAG+SRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  210 NLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQL 337

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Celegans
Match: Y54F10BM.13 (pep chromosome:WBcel235:III:2329577:2331183:-1 gene:WBGene00021867.1 transcript:Y54F10BM.13.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y54F10BM.13)

HSP 1 Score: 89.3521 bits (220), Expect = 3.020e-20
Identity = 51/128 (39.84%), Postives = 76/128 (59.38%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGG-VLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEKSFICPNDGFMKQLKIY 459
            +L  GS + A+++ +L++ +I +I+ V      H  + F Y  I   D+P   +I YF+   EFI+  R+  G V IHC AGISRS T + AY+MK+ KI   +A++K +E   I PN GF +QLK Y
Sbjct:   89 DLLFGSQDVAADLPILENRKITHIVNVGTGIPNHFPKKFEYLQIDILDLPETRIIDYFERVFEFIDKVRQNEGIVFIHCNAGISRSATFVVAYLMKNLKISCREAMDKCRETRSIRPNTGFAQQLKEY 216

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Celegans
Match: C24F3.2 (pep chromosome:WBcel235:IV:10222472:10223745:1 gene:WBGene00007697.1 transcript:C24F3.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C24F3.2)

HSP 1 Score: 82.4185 bits (202), Expect = 1.722e-17
Identity = 69/259 (26.64%), Postives = 130/259 (50.19%), Query Frame = 1

Query:  139 IKYILTVMDSPLL--HKMEDFNYKFIKAYDVPNQDLI--SYFDETSEFIENG-RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVEHSKMKASKTITENTICNEEIFIEALPWIDSSSANGGKVNCPKCACKLGSYTWVGERC-VCGNWVVPAFHIAKQKVDPVK 894
            IK +LT+   P+    K+   +YKF+   D+P++ ++  +  +    +I  G  K   V +HCLA +SRS +I  AY+M   +     A++ I+  +  I PN GF+ QLKI+   +    + +D+YK  +++  P     C ++ +  +  +    T  ++FKC++CR ++F++ ++V H   +A           ++  IE + W++ S A     +   C  KLG++   G +C  C  +V     I + K+D V+
Sbjct:   30 IKRVLTLTTEPISEKQKIGGVDYKFLHLLDMPDEPILDNAILETAVLYINEGVEKEENVGVHCLAAVSRSVSICAAYLMYKNQWPVEKALKMIESVRKTIGPNAGFLAQLKIW--ERSGMSFSADQYKN-LKIDIPGI--TCVDSKTIWRQPVIDDQTK-VRFKCRQCRKVIFNSDNIV-HPLAEAC----------QKYLIEPMAWLNVSGATCSVSH--TCGAKLGTFIASGSKCNGCNKFVRQWIFINRTKLDKVE 269

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Celegans
Match: vhp-1 (Tyrosine-protein phosphatase vhp-1 [Source:UniProtKB/Swiss-Prot;Acc:Q10038])

HSP 1 Score: 77.7962 bits (190), Expect = 3.190e-15
Identity = 52/134 (38.81%), Postives = 75/134 (55.97%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTV-MDSP-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGG-VLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNM 468
            N++LGS  D+ +  +L +L I  ++ + M  P  +   ED N+  I   D   + L  YF    EF+E  R+ G   LIHCLAGISRS T+  +YIM++ K+  +DA   +KE +  I PN  FM QL  Y N+
Sbjct:  111 NIYLGSQIDSLDETMLDALDISVVINLSMTCPKSVCIKEDKNFMRIPVNDSYQEKLSPYFPMAYEFLEKCRRAGKKCLIHCLAGISRSPTLAISYIMRYMKMGSDDAYRYVKERRPSISPNFNFMGQLLEYENV 244

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Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTV-MDSP-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGG-VLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNM 468
            N++LGS  D+ +  +L +L I  ++ + M  P  +   ED N+  I   D   + L  YF    EF+E  R+ G   LIHCLAGISRS T+  +YIM++ K+  +DA   +KE +  I PN  FM QL  Y N+
Sbjct:  111 NIYLGSQIDSLDETMLDALDISVVINLSMTCPKSVCIKEDKNFMRIPVNDSYQEKLSPYFPMAYEFLEKCRRAGKKCLIHCLAGISRSPTLAISYIMRYMKMGSDDAYRYVKERRPSISPNFNFMGQLLEYENV 244

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Celegans
Match: vhp-1 (Tyrosine-protein phosphatase vhp-1 [Source:UniProtKB/Swiss-Prot;Acc:Q10038])

HSP 1 Score: 77.7962 bits (190), Expect = 3.431e-15
Identity = 52/134 (38.81%), Postives = 75/134 (55.97%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTV-MDSP-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGG-VLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNM 468
            N++LGS  D+ +  +L +L I  ++ + M  P  +   ED N+  I   D   + L  YF    EF+E  R+ G   LIHCLAGISRS T+  +YIM++ K+  +DA   +KE +  I PN  FM QL  Y N+
Sbjct:  186 NIYLGSQIDSLDETMLDALDISVVINLSMTCPKSVCIKEDKNFMRIPVNDSYQEKLSPYFPMAYEFLEKCRRAGKKCLIHCLAGISRSPTLAISYIMRYMKMGSDDAYRYVKERRPSISPNFNFMGQLLEYENV 319

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Fly
Match: MKP-4 (gene:FBgn0031044 transcript:FBtr0074741)

HSP 1 Score: 123.635 bits (309), Expect = 3.220e-31
Identity = 89/337 (26.41%), Postives = 167/337 (49.55%), Query Frame = 1

Query:   76 SNLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNY---KFIKAYDVPNQDLISYFDETSEFIENG-RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEK-SFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCT------NTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVEH--------------------SKMKA------------------SKTITENTI-----------CNEEIFIEALPWIDSSSANG-GKVNCPKCACKLGSYTWVGE-RCVCGNWVVPAFHIAKQKVDPVKSM 900
            + L+LG+   A++++ L+S +I +ILT+   PL   + + ++   K+I+  D+P +D++ + +   +FI +   + G VL+HC  G+SRS + + AY+MK   +D   A E +K K  F+ PN GF+ QLK++  M C  D     YK      + + + K        ++V +   ++++ + + I F+C++CR +L   S V+EH                    +K+ A                  S+ I ++++           C   +F+E + W+     N  G++ CPKC  KLG+++W+   +C CG  + PAF++   KV+  K++
Sbjct:   44 TGLFLGNLTAATHMETLRSFKITHILTLDSVPLPQHILEASFLTTKYIQIADMPREDILQHLEGCVDFISSALAQQGNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRFVQPNAGFVSQLKLFRRMGCKIDPNCQRYKIHRLRLAGEQMRKAKILPQSFHSVVRPDPDITRENPEPIVFRCRRCRRVLASKSHVLEHKPRDRPPQEVVPKEKEEVAAAKLPAQSHDQAENHHGARMLEQLSERIRQSSLGSPGHESTPNYCRSILFVEPIAWMHRIMLNTQGRLYCPKCEQKLGNFSWINACKCPCGETMTPAFYLIPSKVELSKAV 380

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Fly
Match: MKP-4 (gene:FBgn0031044 transcript:FBtr0332481)

HSP 1 Score: 123.635 bits (309), Expect = 3.220e-31
Identity = 89/337 (26.41%), Postives = 167/337 (49.55%), Query Frame = 1

Query:   76 SNLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNY---KFIKAYDVPNQDLISYFDETSEFIENG-RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEK-SFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCT------NTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVEH--------------------SKMKA------------------SKTITENTI-----------CNEEIFIEALPWIDSSSANG-GKVNCPKCACKLGSYTWVGE-RCVCGNWVVPAFHIAKQKVDPVKSM 900
            + L+LG+   A++++ L+S +I +ILT+   PL   + + ++   K+I+  D+P +D++ + +   +FI +   + G VL+HC  G+SRS + + AY+MK   +D   A E +K K  F+ PN GF+ QLK++  M C  D     YK      + + + K        ++V +   ++++ + + I F+C++CR +L   S V+EH                    +K+ A                  S+ I ++++           C   +F+E + W+     N  G++ CPKC  KLG+++W+   +C CG  + PAF++   KV+  K++
Sbjct:   44 TGLFLGNLTAATHMETLRSFKITHILTLDSVPLPQHILEASFLTTKYIQIADMPREDILQHLEGCVDFISSALAQQGNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRFVQPNAGFVSQLKLFRRMGCKIDPNCQRYKIHRLRLAGEQMRKAKILPQSFHSVVRPDPDITRENPEPIVFRCRRCRRVLASKSHVLEHKPRDRPPQEVVPKEKEEVAAAKLPAQSHDQAENHHGARMLEQLSERIRQSSLGSPGHESTPNYCRSILFVEPIAWMHRIMLNTQGRLYCPKCEQKLGNFSWINACKCPCGETMTPAFYLIPSKVELSKAV 380

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Fly
Match: CG10089 (gene:FBgn0036369 transcript:FBtr0075823)

HSP 1 Score: 86.2705 bits (212), Expect = 2.190e-18
Identity = 47/134 (35.07%), Postives = 79/134 (58.96%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCT 477
            L++G+Y D+ +   L+  +I +I+ + DSP    + D +Y  + A D P+Q+L  YF   ++FI   R + G VLIHCLAG+SRS T+  AYIM    ++  +A++ ++  ++   PN GF  QL+ +   K +
Sbjct:   12 LYVGNYRDSKDHAQLERFKISHIIAIHDSPR-RLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLS 144

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Fly
Match: CG10089 (gene:FBgn0036369 transcript:FBtr0075821)

HSP 1 Score: 85.8853 bits (211), Expect = 2.501e-18
Identity = 47/134 (35.07%), Postives = 79/134 (58.96%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCT 477
            L++G+Y D+ +   L+  +I +I+ + DSP    + D +Y  + A D P+Q+L  YF   ++FI   R + G VLIHCLAG+SRS T+  AYIM    ++  +A++ ++  ++   PN GF  QL+ +   K +
Sbjct:   12 LYVGNYRDSKDHAQLERFKISHIIAIHDSPR-RLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLS 144

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Fly
Match: CG10089 (gene:FBgn0036369 transcript:FBtr0075822)

HSP 1 Score: 85.8853 bits (211), Expect = 2.501e-18
Identity = 47/134 (35.07%), Postives = 79/134 (58.96%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCT 477
            L++G+Y D+ +   L+  +I +I+ + DSP    + D +Y  + A D P+Q+L  YF   ++FI   R + G VLIHCLAG+SRS T+  AYIM    ++  +A++ ++  ++   PN GF  QL+ +   K +
Sbjct:   12 LYVGNYRDSKDHAQLERFKISHIIAIHDSPR-RLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLS 144

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Zebrafish
Match: dusp12 (dual specificity phosphatase 12 [Source:ZFIN;Acc:ZDB-GENE-050626-91])

HSP 1 Score: 157.918 bits (398), Expect = 1.550e-44
Identity = 104/302 (34.44%), Postives = 156/302 (51.66%), Query Frame = 1

Query:   76 SNLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENG------RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQ--FKCKKCRFLLFDNSSVVEH------SKMKASKTITENTICNEEI-----FIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSMSF*SL 915
            S L++GS  D  + + L +  I +ILTV DS     +  FN KFI+A D  + DL+S  D+ + FI          K   VL+HC  G SRS  ++TAY+MK   +   +A  K++  K  +  N+ F+ QL +Y  M C  D  S  YKQF RL    +       V +  F +  + T   +  ++C+KCR  LF +SS++ H      S     KT   ++   +E      FIE + W++ +      G++ CPKC+ KLGS+ W GE+C CG WV PAF + K +VD +K +S  +L
Sbjct:    6 SGLYIGSVSDLKDAESLSAAGITHILTV-DSEEA-SVTGFNTKFIRALDDESTDLLSRLDDCTSFISEALSTQADSKSAAVLVHCHVGQSRSAAVVTAYLMKTQHLTLQEAYSKLQNIKPDVKMNEEFLDQLALYELMDCKVDTTSPVYKQF-RLKKITEKYPELQNVPKDVFAVDPAQTQNAEAVYRCRKCRRTLFRHSSILSHCVGSGASAFSHKKTRIVSSSAEDETQCTSYFIEPVQWMEQALLGVMDGQLLCPKCSSKLGSFNWYGEQCSCGRWVTPAFQMHKNRVDEIKHISISAL 304

[Close]

Query:   76 SNLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENG------RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQ--FKCKKCRFLLFDNSSVVEH------SKMKASKTITENTICNEEI-----FIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSMSF*SL 915
            S L++GS  D  + + L +  I +ILTV DS     +  FN KFI+A D  + DL+S  D+ + FI          K   VL+HC  G SRS  ++TAY+MK   +   +A  K++  K  +  N+ F+ QL +Y  M C  D  S  YKQF RL    +       V +  F +  + T   +  ++C+KCR  LF +SS++ H      S     KT   ++   +E      FIE + W++ +      G++ CPKC+ KLGS+ W GE+C CG WV PAF + K +VD +K +S  +L
Sbjct:    6 SGLYIGSVSDLKDAESLSAAGITHILTV-DSEEA-SVTGFNTKFIRALDDESTDLLSRLDDCTSFISEALSTQADSKSAAVLVHCHVGQSRSAAVVTAYLMKTQHLTLQEAYSKLQNIKPDVKMNEEFLDQLALYELMDCKVDTTSPVYKQF-RLKKITEKYPELQNVPKDVFAVDPAQTQNAEAVYRCRKCRRTLFRHSSILSHCVGSGASAFSHKKTRIVSSSAEDETQCTSYFIEPVQWMEQALLGVMDGQLLCPKCSSKLGSFNWYGEQCSCGRWVTPAFQMHKNRVDEIKHISISAL 304

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Zebrafish
Match: dusp12 (dual specificity phosphatase 12 [Source:ZFIN;Acc:ZDB-GENE-050626-91])

HSP 1 Score: 148.673 bits (374), Expect = 2.731e-41
Identity = 99/288 (34.38%), Postives = 147/288 (51.04%), Query Frame = 1

Query:   76 SNLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENG------RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQ--FKCKKCRFLLFDNSSVVEH------SKMKASKTITENTICNEEI-----FIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAK 873
            S L++GS  D  + + L +  I +ILTV DS     +  FN KFI+A D  + DL+S  D+ + FI          K   VL+HC  G SRS  ++TAY+MK   +   +A  K++  K  +  N+ F+ QL +Y  M C  D  S  YKQF RL    +       V +  F +  + T   +  ++C+KCR  LF +SS++ H      S     KT   ++   +E      FIE + W++ +      G++ CPKC+ KLGS+ W GE+C CG WV PAF + K
Sbjct:    6 SGLYIGSVSDLKDAESLSAAGITHILTV-DSEEA-SVTGFNTKFIRALDDESTDLLSRLDDCTSFISEALSTQADSKSAAVLVHCHVGQSRSAAVVTAYLMKTQHLTLQEAYSKLQNIKPDVKMNEEFLDQLALYELMDCKVDTTSPVYKQF-RLKKITEKYPELQNVPKDVFAVDPAQTQNAEAVYRCRKCRRTLFRHSSILSHCVGSGASAFSHKKTRIVSSSAEDETQCTSYFIEPVQWMEQALLGVMDGQLLCPKCSSKLGSFNWYGEQCSCGRWVTPAFQMHK 290

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Zebrafish
Match: dusp12 (dual specificity phosphatase 12 [Source:ZFIN;Acc:ZDB-GENE-050626-91])

HSP 1 Score: 89.7373 bits (221), Expect = 3.800e-20
Identity = 66/212 (31.13%), Postives = 102/212 (48.11%), Query Frame = 1

Query:  235 DLISYFDETSEFIENG------RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQ--FKCKKCRFLLFDNSSVVEH------SKMKASKTITENTICNEEI-----FIEALPWIDSS--SANGGKVNCPKCACKLG 804
            DL+S  D+ + FI          K   VL+HC  G SRS  ++TAY+MK   +   +A  K++  K  +  N+ F+ QL +Y  M C  D  S  YKQF RL    +       V +  F +  + T   +  ++C+KCR  LF +SS++ H      S     KT   ++   +E      FIE + W++ +      G++ CPKC+ KLG
Sbjct:   26 DLLSRLDDCTSFISEALSTQADSKSAAVLVHCHVGQSRSAAVVTAYLMKTQHLTLQEAYSKLQNIKPDVKMNEEFLDQLALYELMDCKVDTTSPVYKQF-RLKKITEKYPELQNVPKDVFAVDPAQTQNAEAVYRCRKCRRTLFRHSSILSHCVGSGASAFSHKKTRIVSSSAEDETQCTSYFIEPVQWMEQALLGVMDGQLLCPKCSSKLG 236

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Zebrafish
Match: dusp6 (dual specificity phosphatase 6 [Source:ZFIN;Acc:ZDB-GENE-030613-1])

HSP 1 Score: 91.2781 bits (225), Expect = 8.727e-20
Identity = 57/130 (43.85%), Postives = 79/130 (60.77%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKM----EDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            +L+LG  +D++N+D+L+   IKYIL V  +P L  M     +F YK I   D  +Q+L  +F E   FI+  R    GVL+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  212 HLYLGCAKDSTNLDILEEFGIKYILNV--TPNLPNMFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGLKCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 339

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Xenopus
Match: fcn3 (ficolin 3 [Source:Xenbase;Acc:XB-GENE-6054553])

HSP 1 Score: 154.451 bits (389), Expect = 4.235e-43
Identity = 96/292 (32.88%), Postives = 153/292 (52.40%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIEN--GRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFN---LSKSSTDLIQFKCKKCRFLLFDNSSVVEHS----------KMKASKTITENTICNEEIFIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSM 900
             L+LGS  DA+++  L+   I ++LTV DS +   ++ F  KF+   D  +QDL+S     ++F++   G+    VL+HC AG+SRS  ++ AY+M    +   DA  +++  KS I  N+ F+ QL +Y  M C  D     YKQ+ RL    +       + Q  F     S + T  + ++C+KCR  LF  +S++ H+          K   S    ++T C    F+E + W++ +      G++ CPKC+ KLGS+ W G +C CG WV PAF I K +VD  K++
Sbjct:    7 GLYLGSASDAADLQRLQEAGITHVLTV-DSEVPTGLDGFITKFVHILDDASQDLLSCLPACTDFLKEALGKCGRSVLVHCHAGVSRSAAVIAAYLMHTSNLSLEDACSRLQALKSDIRMNEEFLGQLSLYETMGCDVDMTCASYKQY-RLQKVTEKYPELLKLPQEVFASDPCSMAQTAEVLYRCRKCRRSLFRETSILNHALGTGAAAFAHKRPPSLQKVDSTKCTS-YFVEPVQWMEEALLGVMDGQLLCPKCSSKLGSFNWYGVQCSCGRWVTPAFQIHKNRVDEAKTL 295

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Xenopus
Match: npc1l1 (NPC1 like 1 [Source:Xenbase;Acc:XB-GENE-964011])

HSP 1 Score: 94.3597 bits (233), Expect = 2.141e-20
Identity = 53/127 (41.73%), Postives = 78/127 (61.42%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDS-PLLHKMED-FNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            L+LG+  DA +++ +++  I YI+ V    PL H  +  FNYK + A D   Q+L  YF+E  EFI+   + G  +LIHC AG+SRS TI+ AY+MKH ++   DA + +K ++  I PN  FM QL
Sbjct:  311 LYLGNEHDAQDLETMQTRNISYIVNVTTHLPLYHYEKGVFNYKRLPATDSNKQNLRQYFEEAFEFIDEAHQCGKALLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQL 437

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Xenopus
Match: usp48 (ubiquitin specific peptidase 48 [Source:Xenbase;Acc:XB-GENE-5938602])

HSP 1 Score: 91.6633 bits (226), Expect = 8.938e-20
Identity = 56/127 (44.09%), Postives = 77/127 (60.63%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDS--PLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            L+LG  +D++N+D+L+   IKYIL V  +   L     +F YK I   D  +Q+L  +F E   FI+  R K  GVL+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  211 LYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFRYKQIPISDHWSQNLSQFFPEAISFIDEARGKSCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 337

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Xenopus
Match: lrit2 (leucine-rich repeat, Ig-like and transmembrane domains 2 [Source:Xenbase;Acc:XB-GENE-923281])

HSP 1 Score: 91.6633 bits (226), Expect = 9.161e-20
Identity = 56/128 (43.75%), Postives = 78/128 (60.94%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDS-P-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            +L+LGS  D+ N+D L  L I+YIL V  + P +  K  +F+YK I   D  +Q+L  +F E  EFI+       GVL+HCLAGISRS T+  AY+M+   +  NDA + +K +K+ I PN  FM QL
Sbjct:  201 HLYLGSARDSGNIDTLAKLGIRYILNVTPNLPNIFEKDGEFHYKQIPISDHWSQNLSQFFPEAIEFIDEAASHNCGVLVHCLAGISRSVTVTVAYLMQKLNLSLNDAYDFVKRKKTNISPNFNFMGQL 328

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Xenopus
Match: eci1 (enoyl-CoA delta isomerase 1 [Source:Xenbase;Acc:XB-GENE-999272])

HSP 1 Score: 89.7373 bits (221), Expect = 4.281e-19
Identity = 57/129 (44.19%), Postives = 78/129 (60.47%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKM----EDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            L+LG  +D++N+D+L    IKYIL V  +P L  M     +F YK I   D  +Q+L  +F E   FI+  R K  G+L+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  200 LYLGCAKDSANLDILAKYNIKYILNV--TPNLPNMFEHNGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARSKNCGILVHCLAGISRSVTVTVAYLMQKLNLSLNDAYDFVKRKKSNISPNFNFMGQL 326

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Mouse
Match: Dusp12 (dual specificity phosphatase 12 [Source:MGI Symbol;Acc:MGI:1890614])

HSP 1 Score: 149.058 bits (375), Expect = 6.720e-41
Identity = 99/300 (33.00%), Postives = 146/300 (48.67%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHK---MEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKID---PNDAIEKIKEKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQF-----NLSKSSTDLIQFKCKKCRFLLFDNSSVVEHS-----------KMKASKTITENTICN-EEIFIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSM 900
             L+LG     +    L+   I  +LTV   P        E     F+ A D P  DL+S+ D    FI   R  G  VL+HC AG+SRS  ++ A+IMK  ++      D +  +K ++ +  N+GF  QLK+Y  M    D  S  YKQ+      +   K  N + Q  F      +S+   D I +KC+KCR  LF +SS++ HS           +   S  +T  +       FIE + W++S+      G++ CPKC+ KLGS+ W GE+C CG W+ PAF I K +VD +K +
Sbjct:   33 GLYLGGAAAVAEPGHLREAGITAVLTVDSEPAFPAGAGFEGLRSLFVPALDKPETDLLSHLDRCVAFIGQARSEGRAVLVHCHAGVSRSVAVVMAFIMKTDQLTFEKAYDILRTVKPEAKV--NEGFEWQLKLYEAMGYEVDTSSAFYKQYRLQKVTEKCPKLWN-LPQELFAVDPTTISQGLKDDILYKCRKCRRSLFRHSSILGHSEGSGPIAFAHKRTAPSSVLTTGSQAQCTSYFIEPVQWMESTLLGVMDGQLLCPKCSAKLGSFNWYGEQCSCGRWITPAFQIHKNRVDEMKML 329

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Mouse
Match: Dusp19 (dual specificity phosphatase 19 [Source:MGI Symbol;Acc:MGI:1915332])

HSP 1 Score: 92.4337 bits (228), Expect = 3.878e-21
Identity = 50/128 (39.06%), Postives = 76/128 (59.38%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIY 459
            L LGS + A +++LL+  ++ +IL V        + +F YK I   DVP  +++SYF E  EFIE  + K G VL+HC AG+SR+  I+  ++M   +     A+  +KE +  ICPN GFM+QL+ Y
Sbjct:   72 LLLGSQDAAHDLELLRKHKVTHILNVAYGVENAFLSEFTYKTISILDVPETNILSYFPECFEFIEQAKLKDGVVLVHCNAGVSRAAAIVIGFLMSSEEATFTTALSLVKEARPSICPNPGFMEQLRTY 199

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Mouse
Match: Dusp6 (dual specificity phosphatase 6 [Source:MGI Symbol;Acc:MGI:1914853])

HSP 1 Score: 91.2781 bits (225), Expect = 8.491e-20
Identity = 56/127 (44.09%), Postives = 77/127 (60.63%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDS--PLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            L+LG  +D++N+D+L+   IKYIL V  +   L     +F YK I   D  +Q+L  +F E   FI+  R K  GVL+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  214 LYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Mouse
Match: Dusp9 (dual specificity phosphatase 9 [Source:MGI Symbol;Acc:MGI:2387107])

HSP 1 Score: 92.0485 bits (227), Expect = 9.539e-20
Identity = 57/128 (44.53%), Postives = 78/128 (60.94%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDS-P-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            NL+LGS  D++N++ L  L I+YIL V  + P L  K  DF+YK I   D  +Q+L  +F E   FI+       GVL+HCLAG+SRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  278 NLYLGSARDSANLESLAKLGIRYILNVTPNLPNLFEKNGDFHYKQIPISDHWSQNLSQFFPEAIAFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQL 405

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Mouse
Match: Dusp7 (dual specificity phosphatase 7 [Source:MGI Symbol;Acc:MGI:2387100])

HSP 1 Score: 87.8113 bits (216), Expect = 2.051e-18
Identity = 57/128 (44.53%), Postives = 78/128 (60.94%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKME---DFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            L+LG  +D++N+D+L    IKYIL V  + L +  E   +F YK I   D  +Q+L  +F E   FI+  R K  GVL+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  255 LYLGCAKDSTNLDVLGKYGIKYILNVTPN-LPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQL 381

[Close]

BLAST of dual specificity protein phosphatase 12 vs. UniProt/SwissProt
Match: sp|Q9JIM4|DUS12_RAT (Dual specificity protein phosphatase 12 OS=Rattus norvegicus OX=10116 GN=Dusp12 PE=1 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 3.498e-43
Identity = 103/298 (34.56%), Postives = 146/298 (48.99%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHK---MEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFS-----PDDINKCTNTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVEHSKMK------------ASKTITENTICNEEIFIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSM 900
             L+LG     +  D L+   I  +LTV   P        E     F+ A D P  DL+S+ D    FI   R  G  VL+HC AG+SRS  ++TA+IMK  ++    A E ++  K     N+GF  QLK+Y  M       S  YKQ+ RL       P+  N      +     +S+   D I +KC+KCR  LF  SS+++HS+              +S   T N       FIE + W++S+      G++ CPKC+ KLGS+ W GE+C CG W+ PAF I K +VD VK++
Sbjct:   33 GLYLGGAAAVAGPDYLREAGITAVLTVDSEPAFPAGAGFEGLQSLFVPALDKPETDLLSHLDRCVAFIGQARSEGRAVLVHCHAGVSRSVAVVTAFIMKTEQLTFEKAYENLQTIKPEAKMNEGFEWQLKLYEAMGHEVHTSSAVYKQY-RLQKVTEKYPELRNLPRELFAVDPTTVSQGLKDDILYKCRKCRRSLFRRSSILDHSEGSGPVAFAHKRTGLSSVLTTGNQAQCTSYFIEPVQWMESALLGVMDGQLLCPKCSAKLGSFNWYGEQCSCGRWITPAFQIHKNRVDEVKTL 329

[Close]

BLAST of dual specificity protein phosphatase 12 vs. UniProt/SwissProt
Match: sp|Q9UNI6|DUS12_HUMAN (Dual specificity protein phosphatase 12 OS=Homo sapiens OX=9606 GN=DUSP12 PE=1 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 1.899e-41
Identity = 102/297 (34.34%), Postives = 151/297 (50.84%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTV-MDSPLLHK---MEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQF-----NLSKSSTDLIQFKCKKCRFLLFDNSSVVEHSKMK-----ASKTITENTICNE-------EIFIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVK 894
             L+ G     +  D L+   I  +LTV  + P       +ED    F+ A D P  DL+S+ D    FI   R  G  VL+HC AG+SRS  I+TA++MK  ++    A EK++  K     N+GF  QLK+Y  M    D  S  YKQ+ RL    +       + Q  F      +S+   D + +KC+KCR  LF +SS+++H +       A K +T +++            FIE + W++S+      G++ CPKC+ KLGS+ W GE+C CG W+ PAF I K +VD +K
Sbjct:   33 GLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYKQY-RLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHREGSGPIAFAHKRMTPSSMLTTGRQAQCTSYFIEPVQWMESALLGVMDGQLLCPKCSAKLGSFNWYGEQCSCGRWITPAFQIHKNRVDEMK 328

[Close]

BLAST of dual specificity protein phosphatase 12 vs. UniProt/SwissProt
Match: sp|Q9D0T2|DUS12_MOUSE (Dual specificity protein phosphatase 12 OS=Mus musculus OX=10090 GN=Dusp12 PE=2 SV=1)

HSP 1 Score: 149.058 bits (375), Expect = 4.701e-40
Identity = 99/300 (33.00%), Postives = 146/300 (48.67%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHK---MEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKID---PNDAIEKIKEKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQF-----NLSKSSTDLIQFKCKKCRFLLFDNSSVVEHS-----------KMKASKTITENTICN-EEIFIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSM 900
             L+LG     +    L+   I  +LTV   P        E     F+ A D P  DL+S+ D    FI   R  G  VL+HC AG+SRS  ++ A+IMK  ++      D +  +K ++ +  N+GF  QLK+Y  M    D  S  YKQ+      +   K  N + Q  F      +S+   D I +KC+KCR  LF +SS++ HS           +   S  +T  +       FIE + W++S+      G++ CPKC+ KLGS+ W GE+C CG W+ PAF I K +VD +K +
Sbjct:   33 GLYLGGAAAVAEPGHLREAGITAVLTVDSEPAFPAGAGFEGLRSLFVPALDKPETDLLSHLDRCVAFIGQARSEGRAVLVHCHAGVSRSVAVVMAFIMKTDQLTFEKAYDILRTVKPEAKV--NEGFEWQLKLYEAMGYEVDTSSAFYKQYRLQKVTEKCPKLWN-LPQELFAVDPTTISQGLKDDILYKCRKCRRSLFRHSSILGHSEGSGPIAFAHKRTAPSSVLTTGSQAQCTSYFIEPVQWMESTLLGVMDGQLLCPKCSAKLGSFNWYGEQCSCGRWITPAFQIHKNRVDEMKML 329

[Close]

BLAST of dual specificity protein phosphatase 12 vs. UniProt/SwissProt
Match: sp|O13632|PVH1_SCHPO (Tyrosine-protein phosphatase yvh1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=yvh1 PE=3 SV=1)

HSP 1 Score: 140.969 bits (354), Expect = 4.378e-37
Identity = 88/281 (31.32%), Postives = 147/281 (52.31%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMD-SPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENG-RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEK-SFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLS-KSSTDLIQFKCKKCRFLLFDNSSVVEHSKMKASKTITENTICNEEIFIEALPWIDSSSANG---GKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSM 900
            NL++ S++ AS +       I Y L+ M  +P L   E   + +++  D  +Q+++ YF+++++FI     K   VL+HC AGISRS T++ AY+MK    +  +A+  I E+ S I PN  F++QL++YF      D     Y+Q++     D     T   S+  +  + ++    ++ +CKKCRF+L  +  +V H     +     +T C    F+E + W+      G   G+ +CPKC  K+GSY W G +C C  WV PA  I + +VD V+ +
Sbjct:   53 NLYISSWKTASELVSTSDKGIDYTLSAMSINPNLSVPEQ-QHLWLQIEDSSSQNILQYFEKSNKFIAFALSKNAKVLVHCFAGISRSVTLVAAYLMKENNWNTEEALSHINERRSGISPNANFLRQLRVYFECNYQLDRSLRPYRQWLFRRYGDFAVLNTRVPSEVAYAETVRARAGQLELRCKKCRFVLASSDYLVSHEPKDENNY--SHTRCTH-YFLEPIRWMQPELELGNLEGRFDCPKCNSKIGSYKWQGLQCSCLQWVCPALSILQSRVDAVRKL 329

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BLAST of dual specificity protein phosphatase 12 vs. UniProt/SwissProt
Match: sp|Q9VWF4|DUSK4_DROME (Dual specificity protein phosphatase MPK-4 OS=Drosophila melanogaster OX=7227 GN=MKP-4 PE=1 SV=1)

HSP 1 Score: 123.635 bits (309), Expect = 3.228e-30
Identity = 89/337 (26.41%), Postives = 167/337 (49.55%), Query Frame = 1

Query:   76 SNLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNY---KFIKAYDVPNQDLISYFDETSEFIENG-RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEK-SFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCT------NTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVEH--------------------SKMKA------------------SKTITENTI-----------CNEEIFIEALPWIDSSSANG-GKVNCPKCACKLGSYTWVGE-RCVCGNWVVPAFHIAKQKVDPVKSM 900
            + L+LG+   A++++ L+S +I +ILT+   PL   + + ++   K+I+  D+P +D++ + +   +FI +   + G VL+HC  G+SRS + + AY+MK   +D   A E +K K  F+ PN GF+ QLK++  M C  D     YK      + + + K        ++V +   ++++ + + I F+C++CR +L   S V+EH                    +K+ A                  S+ I ++++           C   +F+E + W+     N  G++ CPKC  KLG+++W+   +C CG  + PAF++   KV+  K++
Sbjct:   44 TGLFLGNLTAATHMETLRSFKITHILTLDSVPLPQHILEASFLTTKYIQIADMPREDILQHLEGCVDFISSALAQQGNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRFVQPNAGFVSQLKLFRRMGCKIDPNCQRYKIHRLRLAGEQMRKAKILPQSFHSVVRPDPDITRENPEPIVFRCRRCRRVLASKSHVLEHKPRDRPPQEVVPKEKEEVAAAKLPAQSHDQAENHHGARMLEQLSERIRQSSLGSPGHESTPNYCRSILFVEPIAWMHRIMLNTQGRLYCPKCEQKLGNFSWINACKCPCGETMTPAFYLIPSKVELSKAV 380

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BLAST of dual specificity protein phosphatase 12 vs. TrEMBL
Match: A0A1S3JIV5 (dual specificity protein phosphatase 12 OS=Lingula unguis OX=7574 GN=LOC106173653 PE=4 SV=1)

HSP 1 Score: 211.075 bits (536), Expect = 2.875e-61
Identity = 118/301 (39.20%), Postives = 169/301 (56.15%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKME-DFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQ-------------FKCKKCRFLLFDNSSVVEHSKMKA-----------------SKTITENTICNEEIFIEALPWI-DSSSANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVD 885
            NL++GS +DAS+ + L+  ++ +ILT+   PL    +  F  KFI A D P  DL+SYF+E  +FIE+G K GGVL+HC AG+SRS TI  AY+M+   I   +A+ KI+EK  + PN GFM+QL ++  M    D K  +YK +         NK +  V QA  +L   + D ++             ++CKKCR +LF  +S + HS+                    S +  + T+C++  FIE + W+ D  S+  GK++CPKC  KLGS+ W GERC CG W+ PAFHI  QKVD
Sbjct:   10 NLYIGSRDDASDTETLQQKEVTHILTIDVKPLPTTQQMTFQCKFIHALDDPETDLLSYFEECIQFIEDGVKMGGVLVHCAAGVSRSATITAAYLMRKHNIGVEEALGKIEEKRHVGPNPGFMQQLHLFEEMGSRLDQKHPKYKIYF-------WNKLSARV-QAARSLEDINADTLEPDPSVGGTGGETVYRCKKCRRILFKQTSFLSHSEGTGEAAFDWRRDSIKHDGSHSSSDEKETMCSQSYFIEPVQWMSDCISSLEGKLSCPKCNAKLGSFNWAGERCPCGAWITPAFHIQIQKVD 302

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BLAST of dual specificity protein phosphatase 12 vs. TrEMBL
Match: A0A210QP86 (Dual specificity protein phosphatase 12 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT04541 PE=3 SV=1)

HSP 1 Score: 196.823 bits (499), Expect = 7.036e-56
Identity = 114/301 (37.87%), Postives = 175/301 (58.14%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKM-EDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQF------IRLFSPDDINKCTNTVSQAQFNLSKSSTDL---IQFKCKKCRFLLFDNSSVVEH------------SKMKASKTIT-----ENTICNEEIFIEALPWI-DSSSANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVK 894
            NL+LGS+  A ++  LK+  I +ILTV +SPL   + E F YKFI  +D+   DL++YF+E  +FI+ G ++G VL+HCLAG SRS T++ AYIMK  ++   +A+  ++  +S + PN+GF +QL +Y  M+   D  ++ ++++      +++ S D       T S  +   + S +D    I +KC+KCR  LF  S ++ H            SK+ ++K  T       T+C + +FIE + W+ +S S   GKV+CPKC  K+GS+ W GE+C CG WV PAFHI   KVD  K
Sbjct:   17 NLYLGSWSAAKDIIRLKARGITHILTVNNSPLPKSVSEQFKYKFIHGFDLEFTDLLNYFEECIKFIDEGIRYGSVLVHCLAGCSRSATMVIAYIMKKKQMGYGEALGIVRRSRSIVHPNEGFKEQLLLYQEMENKIDTTNERFRRYRLKKLALKIHSYD----LGETFSPEELTANPSDSDNKADIVYKCRKCRQALFKKSGLISHNVGEGEAAFDWRSKIPSNKKETVEGRESTTVCTQSLFIEPVRWMAESISEPVGKVSCPKCNSKIGSFVWHGEKCPCGAWVAPAFHIRANKVDESK 313

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BLAST of dual specificity protein phosphatase 12 vs. TrEMBL
Match: A0A5K3ETZ7 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 193.356 bits (490), Expect = 9.473e-55
Identity = 112/285 (39.30%), Postives = 160/285 (56.14%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHK-MEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVEHSKMKASKTITENTICNE-EIFIEALPWIDSSSAN-GGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSMSF*SLSEE 924
             LWLGS   A+ V  L ++ I+ +LTV  SPL     E      IKA DVP+++LI +F E   FI+      GVL+HCLAG+SRS TI+ AYIM  +K+    A + + ++  ICPN GF++QLK++ +M    D  S+ YK+F  L +   I  C  T       +S     L  F C+KCR +LF +  V+ H   K          CN+ E+F  AL W +S +++  GK+ CPKCA K+GSY W GE CVCG W+ PAFH +++ +D +   +  S  +E
Sbjct:    7 GLWLGSRPRANEVPKLIAVGIRSVLTVDMSPLEEPAFEKLKRLHIKASDVPSENLIIHFKEAIAFIDENVS-EGVLVHCLAGVSRSATIVIAYIMWKYKLSYTAARDIVAKRRNICPNAGFVRQLKLFESMNFVVDTSSELYKEFESLRNSYPI--CLPTGKILLHYISSRDPSLSNFACRKCRSVLFHSEDVIHHLCPKKDGDSQSVKPCNQGELFTNALEWFNSQTSDVQGKLYCPKCAVKIGSYNWCGEPCVCGRWLTPAFHFSRKHLDELPGGAIPSAKDE 288

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BLAST of dual specificity protein phosphatase 12 vs. TrEMBL
Match: K1QLY7 (Dual specificity protein phosphatase 12 OS=Crassostrea gigas OX=29159 GN=CGI_10026177 PE=4 SV=1)

HSP 1 Score: 191.815 bits (486), Expect = 4.547e-54
Identity = 110/295 (37.29%), Postives = 165/295 (55.93%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKM-EDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGG-VLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEKS-FICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVS-QAQFNLSKSSTDL----IQFKCKKCRFLLFDNSSVVEH------------SKMKASKTITEN--TICNEEIFIEALPWIDSSSAN-GGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVK 894
            N+++G+       D LK   + +ILT+ + PL   + E++ YKFI   D+   DL+S+F+E   FIE+  + GG VL+HCL G SRS TI  AY+M   KI   +A+E +K K   +CPN+GF+ QL ++  M C  D   ++Y+Q+      D++   T+    + Q +   ++ +L    + FKC+KCR  LF  S +++H             K+   KT   N   +C+   FIE + W+  S  +  GK++CPKC CK+GS+ W GERC CG+WV PAFHI   KVD  K
Sbjct:   15 NIYIGAERAVHRTDQLKQNNVTHILTINNVPLHRSITENYKYKFIYGLDLEFTDLLSHFEECFHFIEDATESGGSVLVHCLMGCSRSATIAIAYLMYKNKITYEEALEIVKNKRPMVCPNEGFISQLLLFEEMGCAMDRTHEKYRQYRLKKLADNLQGSTSEERLKLQADYFDTAEELKKEDVVFKCRKCRQALFKQSGIMKHCVGEGEVAFSWRGKVSTEKTEKPNNPAVCDLSYFIEPVRWMAGSIQDLEGKLSCPKCNCKIGSFLWYGERCPCGSWVAPAFHIQTTKVDMCK 309

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BLAST of dual specificity protein phosphatase 12 vs. TrEMBL
Match: V3ZYI8 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_125232 PE=4 SV=1)

HSP 1 Score: 191.045 bits (484), Expect = 1.122e-53
Identity = 107/302 (35.43%), Postives = 164/302 (54.30%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMED-FNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQ-------FNLSKSSTDLIQFKCKKCRFLLFDNSSVVEHSKMKASKTI-----------------TENTICNEEIFIEALPWIDSSSAN-GGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSMSF 906
            L+LG  E A +++ L+   I +I+T+   PL  +  D F  K+I A D+ + DL++Y DE + FI++G   GGVL+HC  G SRS TI+ AY+M    +   +A++K+K  +  + PN GF+ QL +Y +M    D KS+ ++Q+        +NK + +V   Q       ++    S  L  +KC+KCR  LF +S+++ H + K                       + T+C+  +FIE L W+ S   N  GK+ CPKC+ K+GS+ W GERC CG WV PAFHI   KVD  K ++ 
Sbjct:    8 LFLGGVEAALDIESLEKFGITHIITIDIRPLCQETTDKFTTKYIHAMDLEDTDLLTYIDECNSFIDDGLVKGGVLVHCFVGSSRSATIVIAYLMNKLNLTFQEALDKVKTLRPLVKPNQGFLHQLHLYESMGNKIDVKSNCFRQY-------RLNKLSLSVQAGQQISDHKLYSQLDESNSLNSYKCRKCRQALFKSSALLPHMEGKGKAAFDWRSRIEDDENDIDFQNKDKTLCDRSLFIEPLKWMSSYVHNMEGKILCPKCSAKIGSFIWYGERCPCGTWVAPAFHIQSSKVDLCKPINI 302

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Cavefish
Match: dusp12 (dual specificity phosphatase 12 [Source:NCBI gene;Acc:103030551])

HSP 1 Score: 150.214 bits (378), Expect = 1.850e-41
Identity = 96/302 (31.79%), Postives = 155/302 (51.32%), Query Frame = 1

Query:   76 SNLWLGSYEDASNVDLLKSLQIKYILTV-MDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENG-----RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTD--LIQFKCKKCRFLLFDNSSVVEH-----------SKMKASKTITENTICNEEIFIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSMSF*SL 915
            + L +GS  D  + + L +  + +ILTV  + P    +  F+ KF+ A D  + DL+S  D+   FI         K   VL+HC  G SRS  ++TAY+MK  K+   DA  K+++ K  +  N+ F+ QL +Y +M C  D  S  YKQ+ RL    +       + +  F +  + T    + ++C+KCR  LF +SS++ H            ++    +  + T C    FIE + W++ +      G++ CPKC+ KLGS+ W G++C CG WV PAF + K +VD +K +S  +L
Sbjct:   29 TGLCIGSVSDLKDPEALINAGVTHILTVDSEEP---NISGFHKKFVHALDDSSTDLLSRLDDCVHFITEALAASEGKASSVLVHCHVGQSRSAAVVTAYLMKTKKLSLQDAYAKLQQLKPDVKMNEEFLDQLVLYESMNCELDTNSPLYKQY-RLRKVTEKYPELQKLPKEVFAVDPAQTQNTEVVYRCRKCRRTLFRHSSILSHCLGSGASAFSHKRVSVGGSAEDQTQCTS-YFIEPVQWMEEALLGVMDGQLLCPKCSSKLGSFNWYGDQCSCGRWVTPAFQMHKNRVDEIKHISIPAL 325

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Cavefish
Match: dusp12 (dual specificity phosphatase 12 [Source:NCBI gene;Acc:103030551])

HSP 1 Score: 95.5153 bits (236), Expect = 8.871e-22
Identity = 71/246 (28.86%), Postives = 119/246 (48.37%), Query Frame = 1

Query:   76 SNLWLGSYEDASNVDLLKSLQIKYILTV-MDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-----KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTD--LIQFKCKKCRFLLFDNSSVV-----------EHSKMKASKTITENTICNEEIFIEALPWIDSS 753
            + L +GS  D  + + L +  + +ILTV  + P    +  F+ KF+ A D  + DL+S  D+   FI         K   VL+HC  G SRS  ++TAY+MK  K+   DA  K+++ K  +  N+ F+ QL +Y +M C  D  S  YKQ+ RL    +       + +  F +  + T    + ++C+KCR  LF +SS++            H ++    +  + T C    FIE + W++ +
Sbjct:   29 TGLCIGSVSDLKDPEALINAGVTHILTVDSEEP---NISGFHKKFVHALDDSSTDLLSRLDDCVHFITEALAASEGKASSVLVHCHVGQSRSAAVVTAYLMKTKKLSLQDAYAKLQQLKPDVKMNEEFLDQLVLYESMNCELDTNSPLYKQY-RLRKVTEKYPELQKLPKEVFAVDPAQTQNTEVVYRCRKCRRTLFRHSSILSHCLGSGASAFSHKRVSVGGSAEDQTQCT-SYFIEPVQWMEEA 269

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Cavefish
Match: dusp12 (dual specificity phosphatase 12 [Source:NCBI gene;Acc:103030551])

HSP 1 Score: 94.7449 bits (234), Expect = 2.306e-21
Identity = 71/246 (28.86%), Postives = 119/246 (48.37%), Query Frame = 1

Query:   76 SNLWLGSYEDASNVDLLKSLQIKYILTV-MDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-----KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTD--LIQFKCKKCRFLLFDNSSVV-----------EHSKMKASKTITENTICNEEIFIEALPWIDSS 753
            + L +GS  D  + + L +  + +ILTV  + P    +  F+ KF+ A D  + DL+S  D+   FI         K   VL+HC  G SRS  ++TAY+MK  K+   DA  K+++ K  +  N+ F+ QL +Y +M C  D  S  YKQ+ RL    +       + +  F +  + T    + ++C+KCR  LF +SS++            H ++    +  + T C    FIE + W++ +
Sbjct:   44 TGLCIGSVSDLKDPEALINAGVTHILTVDSEEP---NISGFHKKFVHALDDSSTDLLSRLDDCVHFITEALAASEGKASSVLVHCHVGQSRSAAVVTAYLMKTKKLSLQDAYAKLQQLKPDVKMNEEFLDQLVLYESMNCELDTNSPLYKQY-RLRKVTEKYPELQKLPKEVFAVDPAQTQNTEVVYRCRKCRRTLFRHSSILSHCLGSGASAFSHKRVSVGGSAEDQTQCT-SYFIEPVQWMEEA 284

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Cavefish
Match: dusp6 (dual specificity phosphatase 6 [Source:NCBI gene;Acc:103030496])

HSP 1 Score: 92.8189 bits (229), Expect = 3.190e-20
Identity = 65/181 (35.91%), Postives = 102/181 (56.35%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDS-P-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQF 609
            +L+LG  +D++N+D+L+   IKYIL V  + P L     +F YK I   D  +Q+L  +F E   FI+  R +  GVL+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL               ++++ + + SP D N+ T+  SQA +  + ++ ++ Q 
Sbjct:  252 HLYLGCAKDSTNLDILEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGQKCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLL--------------DFERTLGIQSPCD-NRATSAPSQALYFSTPTNHNVFQL 417

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Cavefish
Match: dusp6 (dual specificity phosphatase 6 [Source:NCBI gene;Acc:103030496])

HSP 1 Score: 92.0485 bits (227), Expect = 4.441e-20
Identity = 65/181 (35.91%), Postives = 102/181 (56.35%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDS-P-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQF 609
            +L+LG  +D++N+D+L+   IKYIL V  + P L     +F YK I   D  +Q+L  +F E   FI+  R +  GVL+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL               ++++ + + SP D N+ T+  SQA +  + ++ ++ Q 
Sbjct:  212 HLYLGCAKDSTNLDILEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGQKCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLL--------------DFERTLGIQSPCD-NRATSAPSQALYFSTPTNHNVFQL 377

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Sea Lamprey
Match: dusp7 (dual specificity phosphatase 7 [Source:ZFIN;Acc:ZDB-GENE-030131-5457])

HSP 1 Score: 92.0485 bits (227), Expect = 1.193e-21
Identity = 57/128 (44.53%), Postives = 78/128 (60.94%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDS-P-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            +L+LG  +D+SN++ L    I+YIL V  + P    ++ DF YK I   D  NQ+L  +F E   FI+  R K  GVL+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  103 HLFLGCAQDSSNMEALAQHGIRYILNVTPNLPNTFERIADFKYKQIPISDHWNQNLSQFFPEAIAFIDEARNKQCGVLVHCLAGISRSVTVTVAYLMQKLSLPLNDAYDFVKHKKSNISPNFNFMGQL 230

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Sea Lamprey
Match: dusp22b (dual specificity phosphatase 22b [Source:NCBI gene;Acc:100002272])

HSP 1 Score: 81.6481 bits (200), Expect = 5.943e-19
Identity = 45/130 (34.62%), Postives = 79/130 (60.77%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQLKIYFN 465
            L+LG+ +D++++  L+   I +IL+V D+     +E+  Y  I+  D P+Q+L  +F +  +FI   R +  G L+HCLAG+SRS T++ AYIM    +   +A+  +K  ++   PN GF +QL+++ N
Sbjct:   12 LYLGNIKDSADLKQLRDHNITHILSVHDAAR-EALEEMTYLCIQVSDTPSQNLTQHFKDCIQFIHKCRMEKKGCLVHCLAGVSRSVTMVVAYIMTVTSLGWEEAMVAVKTARTCANPNLGFQQQLQMFQN 140

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Sea Lamprey
Match: dusp6 (dual specificity phosphatase 6 [Source:ZFIN;Acc:ZDB-GENE-030613-1])

HSP 1 Score: 84.3445 bits (207), Expect = 4.163e-18
Identity = 52/127 (40.94%), Postives = 72/127 (56.69%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSP--LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            L+LG   D++N+  L    I+YIL V  +         DF YK I   D  +Q+L  +F E   FI+  R K  GVL+HCLAGISRS T+  AY+M+   +  NDA + ++ +K+ I PN  FM QL
Sbjct:  227 LYLGCARDSTNLAALAEHGIRYILNVTPNVPNAFESRRDFVYKQIPVPDHWSQNLSQFFPEAIAFIDEARQKKCGVLVHCLAGISRSVTVTVAYLMQTLNLSLNDAYDLVRNKKANISPNFNFMGQL 353

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BLAST of dual specificity protein phosphatase 12 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006071.1 (pep scaffold:Pmarinus_7.0:GL479824:161791:175185:-1 gene:ENSPMAG00000005490.1 transcript:ENSPMAT00000006071.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.337 bits (194), Expect = 4.556e-18
Identity = 48/122 (39.34%), Postives = 71/122 (58.20%), Query Frame = 1

Query:  103 DASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPN----QDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            DA ++  L+ L I  +L V      ++    +YK + A D  N    Q+L  YF+E  EFIE+  + G G+L+HC AG+SRS TI+ AY+MKH ++   DA + +K ++  I PN  FM QL
Sbjct:    1 DAQDLSKLQRLGIGLVLNVTAH---YERGGLHYKRLPANDSDNDSDKQNLRQYFEEAFEFIEDAHRRGQGLLVHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQL 119

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Sea Lamprey
Match: dusp10 (dual specificity phosphatase 10 [Source:ZFIN;Acc:ZDB-GENE-041014-271])

HSP 1 Score: 77.0258 bits (188), Expect = 1.273e-16
Identity = 55/127 (43.31%), Postives = 77/127 (60.63%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDS-PLLH-KMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            L+LG+ +DA ++  L+ L I YI+ V    PL H +     YK + A D   Q+L  YF+E  EFIE   + G G+LIHC AG+SRS TI+ AY+MKH ++   DA + +K ++  I PN  FM QL
Sbjct:   54 LFLGNEQDAQDLAQLQRLNIGYIINVTSHLPLYHYERGALRYKRLPATDSCKQNLRQYFEEAFEFIEEAYQSGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQL 180

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Yeast
Match: YVH1 (Dual specificity protein phosphatase; regulates growth, sporulation, and glycogen accumulation in a cAMP-dependent protein kinase cascade dependent manner; mutants are defective in 60S ribosome assembly; positively regulates pre-autophagosomal structure (PAS) formation upon nitrogen starvation or rapamycin treatment [Source:SGD;Acc:S000001465])

HSP 1 Score: 115.931 bits (289), Expect = 1.972e-29
Identity = 94/325 (28.92%), Postives = 142/325 (43.69%), Query Frame = 1

Query:  121 LLKSLQIKYILTVMDSPLLHK---MEDFNYKFIKAYDVPNQDLISYFDETSEFIEN------------------GRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQLKIYFNMKCTGD--------YKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQF-----------KCKKCRFLLFDNSSVVEHSKMKASKT----------------ITENTICNEEIFIEALPWIDSSSANG----GKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVD--PVKSMSF 906
            L     I +IL+V+   ++ +    + +  K I   D    D++ YFDET+ FI+                     + G V  HC AG+SRS T + AY+M  + +  + A+  +K +K  + PN+ FM+QL ++  M   GD        YK  + KQ I+L  P      +N+     F  S+SS DL +            +CKKCR  L  ++S + H       +                I E+       FIE L W+           GK +CP C+ K+G Y W G RC CG WV+PA H+   KVD  P++S + 
Sbjct:   33 LGAEFNITHILSVIKFQVIPEYLIRKGYTLKNIPIDDDDVTDVLQYFDETNRFIDQCLFPNEVEYSPRLVDFKKKPQRGAVFAHCQAGLSRSVTFIVAYLMYRYGLSLSMAMHAVKRKKPSVEPNENFMEQLHLFEKM--GGDFVDFDNPAYKQWKLKQSIKL-DPSGSELVSNS---GMFKDSESSQDLDKLTEAEKSKVTAVRCKKCRTKLALSTSFIAHDPPSKESSEGHFIKRAANSHRIIDIQESQANCSHFFIEPLKWMQPELQGKQELEGKFSCPGCSSKVGGYNWKGSRCSCGKWVIPAIHLQTSKVDQFPLQSTAL 351

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Yeast
Match: MSG5 (Dual-specificity protein phosphatase; exists in 2 isoforms; required for maintenance of a low level of signaling through the cell integrity pathway, adaptive response to pheromone; regulates and is regulated by Slt2p; dephosphorylates Fus3p; MSG5 has a paralog, SDP1, that arose from the whole genome duplication [Source:SGD;Acc:S000004998])

HSP 1 Score: 48.1358 bits (113), Expect = 1.386e-6
Identity = 36/113 (31.86%), Postives = 55/113 (48.67%), Query Frame = 1

Query:  298 VLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEKSF-ICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDI-----NKCTNTVSQAQF-------NLSKSSTD 597
            +L+HC  G+SRS +++ AYIM+++ +  NDA  K+K  +  I PN G + QL  +  M         E  + + +   DDI     +  T + S A F       NLS S  D
Sbjct:  315 ILVHCQCGVSRSASLIVAYIMRYYGLSLNDAYNKLKGVAKDISPNMGLIFQLMEWGTMLSKN--SPGEEGETVHMPEEDDIGNNEVSSTTKSYSSASFRSFPMVTNLSSSPND 425

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Nematostella
Match: EDO34381 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPK6])

HSP 1 Score: 172.94 bits (437), Expect = 6.596e-51
Identity = 113/289 (39.10%), Postives = 153/289 (52.94%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYK---FIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE--KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLS-KSSTDLIQ--FKCKKCRFLLFDNSSVVEH---------SKMKASKTITENTICNEEIFIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVD 885
             L+ G+ EDA N   LK   I  +LT+ DS  L  ++D   K   F+   D PN DL+S+ DE   FIE+G K    VL+HCLAG+SRS  ++ AYIMK  ++  +DA+ K+ E   S I PN GF+ QLKIY  M C  +  S  +KQ+        I   T   S A F L  KS  +  Q  +KCKKCR  LF++ S VEH          K   +   T   +C   +FIE + W+ S       GK+ CPKC+ +LGS+ W G +C C  W+ PAF   K ++D
Sbjct:    7 GLYAGTREDAMNYCQLKEAAINRVLTI-DSQSLPDLQDDRQKKSLFVYCLDEPNADLLSHLDECIRFIEDGIKHEEPVLVHCLAGVSRSIAVILAYIMKSDQVSLDDAVNKMSEIYSSEISPNQGFLDQLKIYEEMGCKVNTSSALFKQYRLQLLASQIQG-TIFTSCALFILEFKSPMERSQNIYKCKKCRVTLFNSGSTVEHETGSMPFNWQKKDQTHLNTSMPLCTS-LFIEPVEWMLSGLQGTVAGKICCPKCSARLGSFNWAGMQCSCAAWITPAFQFHKNRID 292

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Nematostella
Match: EDO37000 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGZ1])

HSP 1 Score: 89.7373 bits (221), Expect = 1.278e-21
Identity = 54/132 (40.91%), Postives = 77/132 (58.33%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPL----LHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGG-VLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEKS-FICPNDGFMKQLKIY 459
            L+LGS E A++ DL+  L IK+IL +  +P+      + ED  YK I+  D   +D+  +FDE   FI+  R  G  VL+HC AG+SRS T+  AY+M+H  +  N+A + +KEK   I PN  FM  L  Y
Sbjct:    5 LFLGSEEGAADEDLIDRLAIKFILNL--TPVCPNFFSEREDIIYKRIQINDSYQEDIGQHFDEAIAFIDEARSRGSSVLVHCHAGVSRSATVTVAYVMQHLGLSLNEAYQFVKEKRPTISPNLNFMGHLLKY 134

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Nematostella
Match: EDO34920 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN01])

HSP 1 Score: 89.3521 bits (220), Expect = 2.413e-21
Identity = 54/136 (39.71%), Postives = 80/136 (58.82%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDS--PLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQLKIYFNMKCT 477
            L+LG+  D+ + + L+   I +IL++ D+  PL    ED  YK I A D P+QDL+ +F E  EFI + R K    L+HC+AGISRS TI  AYIM   ++     ++ I+  +S   PN GF +QL+ ++N   T
Sbjct:   12 LYLGNIRDSKDAEQLQEHNITHILSIHDNANPL---REDIMYKCIHAADSPDQDLMPFFQECIEFIHSCRVKEMNCLVHCIAGISRSTTICAAYIMTITELSWRQTLQAIRANRSIANPNYGFKRQLQDFYNKHLT 144

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Nematostella
Match: EDO45432 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTA2])

HSP 1 Score: 88.9669 bits (219), Expect = 8.546e-20
Identity = 56/127 (44.09%), Postives = 74/127 (58.27%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVM-DSP-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            L+LGS +DASN++LL+  +I Y+L V  D P     +E F YK +   D    +L   F E   FI+ GR K   VL+HCLAGISRS TI  AY+M    +  N+A + +K  KS + PN  FM QL
Sbjct:  193 LYLGSEKDASNIELLRKHKISYVLNVTHDRPNTFAHIEGFKYKNLPVEDNLMANLTELFPEAFAFIDEGRQKSSNVLVHCLAGISRSVTITIAYLMSSQHLSLNEAYDFVKARKSNVSPNFNFMGQL 319

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Nematostella
Match: EDO35438 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLH2])

HSP 1 Score: 79.7221 bits (195), Expect = 3.951e-18
Identity = 43/124 (34.68%), Postives = 70/124 (56.45%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQL 450
            L+LGS + A   + L+   I +IL V    +    +DF YK I+  D+P  DL++   +  +FI +G + G VL+HC AG+SRS  ++ AY+M    +    A   ++E +  + PN+GF +QL
Sbjct:    5 LFLGSQDGAHCYEELQRNNITHILNVATGVVNVFAKDFTYKNIELLDLPETDLVAQLPQMFQFINDGLQAGAVLVHCNAGVSRSPAVVIAYLMHKRLLSLGQAFNVVREQRPCVKPNEGFWRQL 128

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Medaka
Match: dusp12 (dual specificity phosphatase 12 [Source:NCBI gene;Acc:101155145])

HSP 1 Score: 160.614 bits (405), Expect = 1.022e-45
Identity = 94/290 (32.41%), Postives = 154/290 (53.10%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMD---SPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGV-LIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQF--NLSKSSTDLIQFKCKKCRFLLFDNSSVVEHSKMKASKTITENTICN-------EEIFIEALPWIDSS--SANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSM 900
             +++G+  D ++   L +  + +IL+V      P +    +F  K+I A D    DL+SY D  + FI+   K GG  L+HC AG SRS TI+TAY+MK   +   +A +++K  K  +  N GF +QL++Y +M C  D  S  YKQ+ RL    +       V +  F  + + SS+  + ++C+KCR  LF  SS++ H     +   +     N          FIE + W++ +      G++ CPKC+ KLGS++W G++C CG WV PAF + + +VD ++ +
Sbjct:    7 GVYIGTAADLNDCQALAAASVTHILSVESVDPGPQIPATGNFIRKWINALDEETTDLLSYLDACNIFIDEAVKGGGATLVHCHAGRSRSATIVTAYLMKKHHLAFPEAYQRLKSVKQDVQVNRGFEEQLQLYESMLCQVDTSSALYKQY-RLNKIAERYPELQQVPRDIFANDPAHSSSSEVSYRCRKCRRTLFRGSSILSHPVGDGASAFSHKKTSNLSGEVQCTSYFIEPVQWMEQALLGVMNGQLLCPKCSSKLGSFSWCGDQCSCGRWVTPAFQLHRNRVDEIRQI 295

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Medaka
Match: dusp7 (dual specificity phosphatase 7 [Source:NCBI gene;Acc:101158099])

HSP 1 Score: 91.2781 bits (225), Expect = 8.542e-20
Identity = 61/152 (40.13%), Postives = 85/152 (55.92%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDS-PLLHKME-DFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL-----KIYFNMKCTGDYKSDEYKQF 510
            L+LG  +D++N+D+L    IKYIL V  + P + + E DF YK I   D  +Q+L  +F E   FI+  R K  G+L+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL      +  N  C     S  + Q 
Sbjct:  214 LYLGCAKDSANLDVLSKYNIKYILNVTPNLPNMFEHEGDFKYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGILVHCLAGISRSVTVTVAYLMQKLNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLNSPCDNHSASPPHDQL 365

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Medaka
Match: dusp6 (dual specificity phosphatase 6 [Source:NCBI gene;Acc:101164462])

HSP 1 Score: 90.1225 bits (222), Expect = 1.920e-19
Identity = 56/128 (43.75%), Postives = 79/128 (61.72%), Query Frame = 1

Query:   79 NLWLGSYEDASNVDLLKSLQIKYILTVMDS-P-LLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            +L+LG  +D++N+D+L+   IKYIL V  + P L     +F YK I   D  +Q+L  +F E   FI+  R +  GVL+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  214 HLYLGCAKDSTNLDVLEEYGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGQKRGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQL 341

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Medaka
Match: ENSORLT00000014597.2 (dual specificity protein phosphatase 7 [Source:NCBI gene;Acc:101175078])

HSP 1 Score: 87.8113 bits (216), Expect = 9.818e-19
Identity = 56/129 (43.41%), Postives = 77/129 (59.69%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMED----FNYKFIKAYDVPNQDLISYFDETSEFIENGR-KFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQL 450
            L+LG  +D++N+D+L    I YIL V  +P L  M +    F YK I   D  +Q+L  +F E   FI+  R K  G+L+HCLAGISRS T+  AY+M+   +  NDA + +K +KS I PN  FM QL
Sbjct:  194 LYLGCAKDSANLDVLGQYNITYILNV--TPNLPNMFEHDGHFRYKQIPISDHWSQNLSQFFPEAISFIDEARSKRCGILVHCLAGISRSVTVTVAYLMQRLNLSLNDAYDFVKRKKSNISPNFNFMGQL 320

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Medaka
Match: si:ch211-203d1.3 (slingshot protein phosphatase 3 [Source:NCBI gene;Acc:101173795])

HSP 1 Score: 87.0409 bits (214), Expect = 4.276e-18
Identity = 50/141 (35.46%), Postives = 77/141 (54.61%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFG-GVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKE-KSFICPNDGFMKQLKIYFNMKCTGDYKSDE 498
            L+LGS  +A+N + L+   + YIL V         E F Y  I+ YDV + +L+ ++ +T  FI   RK G  VL+HC  G+SRS + + AY MK  +     A+  ++E +S + PN+GFMKQL+ Y  +      +  E
Sbjct:  308 LYLGSEWNAANFEELQKNNVGYILNVTREIDNFFPESFTYMNIRVYDVESTNLLPHWPDTYNFINTARKTGQAVLVHCKMGVSRSASTVIAYAMKQQRWSLETALTYVRECRSIVNPNEGFMKQLQTYNGILTASQMRHSE 448

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Planmine SMEST
Match: SMESG000014789.1 (SMESG000014789.1)

HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0
Identity = 277/277 (100.00%), Postives = 277/277 (100.00%), Query Frame = 1

Query:   76 SNLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVEHSKMKASKTITENTICNEEIFIEALPWIDSSSANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSMSF 906
            SNLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVEHSKMKASKTITENTICNEEIFIEALPWIDSSSANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSMSF
Sbjct:    6 SNLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVEHSKMKASKTITENTICNEEIFIEALPWIDSSSANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKVDPVKSMSF 282

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Planmine SMEST
Match: SMESG000001338.1 (SMESG000001338.1)

HSP 1 Score: 155.221 bits (391), Expect = 5.890e-44
Identity = 99/283 (34.98%), Postives = 142/283 (50.18%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPL---LHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEK-SFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQFIRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVEH------------SKMKASKTITENTICNEEIFIEALPWIDSSSANGGKVNCPKCACKLGSYTWVGERCVCGNWVVPAFHIAKQKV 882
            L+LG Y+DA+N D+L    I +ILTV +  L    HK   F Y F++       DL+S F ET+EFIE G   GGVLIHC  G++RS T++ A+IM   K    +A + +K K + ICP D FM QL++Y  M    D     Y+ +   F+       +    ++ F       +   F+C KC+F LF   ++  H            S  +  +     T  NE I++E + W+D +S + G VNCP C  K+G Y   GE C CG WV PA  I +  +
Sbjct:    8 LFLGGYDDATNSDILMKNNITHILTVHELKLSRNYHK--GFQYMFVETKSDQEIDLLSRFVETNEFIEKGMNSGGVLIHCQFGMARSATLVIAFIMSLQKTTVQEAFDFVKRKRNIICPTDSFMYQLRLYEFMNYKLDLSIPIYRLYKNFFA------ISKKFDKSNFVFGSIDRNQKIFQCYKCKFDLFSEGNINFHLSEENEIDFILSSFFECLEEKNMKTCKNENIYVELMDWMDLNSVSRGDVNCPGCNMKIGKYCLNGEFCSCGIWVFPAVFIDRLSI 282

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Planmine SMEST
Match: SMESG000078269.1 (SMESG000078269.1)

HSP 1 Score: 86.2705 bits (212), Expect = 3.375e-18
Identity = 51/143 (35.66%), Postives = 87/143 (60.84%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENG-RKFGGVLIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIKEKSFIC-PNDGFMKQL-KIYFNMKCTGDYKSDEY 501
            L+LG+  D++++++L+  +I +IL V  +   ++ + F YK + A D   QD+ +Y+DE  +FI+    K G VL+HC AG+SRS TI+ AY++KH K+     I  ++ K  I  PN  F+ QL + Y +++   + +S EY
Sbjct:  232 LFLGNEMDSNDIEVLQEKKITHILNVTTNVPFYREDLFVYKRLSATDCNRQDMRAYYDEAIQFIDEAYSKNGKVLVHCWAGVSRSATIVAAYLLKHTKLSVLQTIMFLQSKRPIVEPNFNFLGQLERFYCDLEKGVESRSKEY 374

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Planmine SMEST
Match: SMESG000070817.1 (SMESG000070817.1)

HSP 1 Score: 85.1149 bits (209), Expect = 1.841e-17
Identity = 51/128 (39.84%), Postives = 74/128 (57.81%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGGV-LIHCLAGISRSGTILTAYIMKHFKIDPNDAIEKIK-EKSFICPNDGFMKQLKIY 459
            L+LGS  +ASN + L   +I +IL V         + F Y+ I  +D  +  L+ +FD   +FI   +   GV L+HC  GISRS +I+ +YIMK F +    A+E +K ++  I PNDGFM+QLK Y
Sbjct:  312 LYLGSTYNASNFEELVKNKITHILNVTRESENFFRDQFEYENILVFDNEDTKLLKHFDLCHKFITQAKIINGVCLVHCQRGISRSASIVISYIMKEFNMTFEKALEFVKGKRDCIKPNDGFMQQLKTY 439

[Close]

BLAST of dual specificity protein phosphatase 12 vs. Planmine SMEST
Match: SMESG000035381.1 (SMESG000035381.1)

HSP 1 Score: 79.337 bits (194), Expect = 5.555e-16
Identity = 55/140 (39.29%), Postives = 81/140 (57.86%), Query Frame = 1

Query:   82 LWLGSYEDASNVDLLKSLQIKYILTV-MDSPLLHKMEDFNYKFIKAYDVPNQDLISYFDETSEFIENGRKFGG-VLIHCLAGISRSGTILTAYIMKH-FKIDPNDAIEKIK-EKSFICPNDGFMKQLKIYFNMKCTGDYK 489
            L+LG+  DA N   L + +I ++L V + +  L +++ F  K I   D   QDLI +F +  +FIE  RK  G +L+HC AGISRS TI+ AY+M H   +D N+A + +K  ++ I PN  FM QL  + N    G +K
Sbjct:  221 LYLGNELDALNSTFLTNNKITHVLNVTIKASFLDEIK-FKSKRINCNDNNVQDLIQFFPDAFKFIELARKSNGRILVHCQAGISRSATIVIAYLMSHCSNLDLNNAHQWVKRRRTIISPNFNFMGQLVQFENDLINGTFK 359

The following BLAST results are available for this feature:

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Human
BLAST of dual specificity protein phosphatase 12 vs. Ensembl Celegans
BLAST of dual specificity protein phosphatase 12 vs. Ensembl Fly
BLAST of dual specificity protein phosphatase 12 vs. Ensembl Zebrafish
BLAST of dual specificity protein phosphatase 12 vs. Ensembl Xenopus
BLAST of dual specificity protein phosphatase 12 vs. Ensembl Mouse
BLAST of dual specificity protein phosphatase 12 vs. UniProt/SwissProt
BLAST of dual specificity protein phosphatase 12 vs. TrEMBL
BLAST of dual specificity protein phosphatase 12 vs. Ensembl Cavefish
BLAST of dual specificity protein phosphatase 12 vs. Ensembl Sea Lamprey
BLAST of dual specificity protein phosphatase 12 vs. Ensembl Yeast
BLAST of dual specificity protein phosphatase 12 vs. Ensembl Nematostella
BLAST of dual specificity protein phosphatase 12 vs. Ensembl Medaka
BLAST of dual specificity protein phosphatase 12 vs. Planmine SMEST

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
DUSP12	3.955e-42	34.34	dual specificity phosphatase 12 [Source:HGNC Symbo...	[more]
DUSP19	5.192e-21	39.84	dual specificity phosphatase 19 [Source:HGNC Symbo...	[more]
DUSP6	2.912e-20	44.88	dual specificity phosphatase 6 [Source:HGNC Symbol...	[more]
DUSP9	4.851e-20	44.53	dual specificity phosphatase 9 [Source:HGNC Symbol...	[more]
DUSP9	4.851e-20	44.53	dual specificity phosphatase 9 [Source:HGNC Symbol...	[more]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Y54F10BM.13	3.020e-20	39.84	pep chromosome:WBcel235:III:2329577:2331183:-1 gen...	[more]
C24F3.2	1.722e-17	26.64	pep chromosome:WBcel235:IV:10222472:10223745:1 gen...	[more]
vhp-1	3.190e-15	38.81	Tyrosine-protein phosphatase vhp-1 [Source:UniPro...	[more]
vhp-1	3.190e-15	38.81	Tyrosine-protein phosphatase vhp-1 [Source:UniPro...	[more]
vhp-1	3.431e-15	38.81	Tyrosine-protein phosphatase vhp-1 [Source:UniPro...	[more]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MKP-4	3.220e-31	26.41	gene:FBgn0031044 transcript:FBtr0074741	[more]
MKP-4	3.220e-31	26.41	gene:FBgn0031044 transcript:FBtr0332481	[more]
CG10089	2.190e-18	35.07	gene:FBgn0036369 transcript:FBtr0075823	[more]
CG10089	2.501e-18	35.07	gene:FBgn0036369 transcript:FBtr0075821	[more]
CG10089	2.501e-18	35.07	gene:FBgn0036369 transcript:FBtr0075822	[more]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dusp12	1.550e-44	34.44	dual specificity phosphatase 12 [Source:ZFIN;Acc:Z...	[more]
dusp12	1.550e-44	34.44	dual specificity phosphatase 12 [Source:ZFIN;Acc:Z...	[more]
dusp12	2.731e-41	34.38	dual specificity phosphatase 12 [Source:ZFIN;Acc:Z...	[more]
dusp12	3.800e-20	31.13	dual specificity phosphatase 12 [Source:ZFIN;Acc:Z...	[more]
dusp6	8.727e-20	43.85	dual specificity phosphatase 6 [Source:ZFIN;Acc:ZD...	[more]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fcn3	4.235e-43	32.88	ficolin 3 [Source:Xenbase;Acc:XB-GENE-6054553]	[more]
npc1l1	2.141e-20	41.73	NPC1 like 1 [Source:Xenbase;Acc:XB-GENE-964011]	[more]
usp48	8.938e-20	44.09	ubiquitin specific peptidase 48 [Source:Xenbase;Ac...	[more]
lrit2	9.161e-20	43.75	leucine-rich repeat, Ig-like and transmembrane dom...	[more]
eci1	4.281e-19	44.19	enoyl-CoA delta isomerase 1 [Source:Xenbase;Acc:XB...	[more]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Dusp12	6.720e-41	33.00	dual specificity phosphatase 12 [Source:MGI Symbol...	[more]
Dusp19	3.878e-21	39.06	dual specificity phosphatase 19 [Source:MGI Symbol...	[more]
Dusp6	8.491e-20	44.09	dual specificity phosphatase 6 [Source:MGI Symbol;...	[more]
Dusp9	9.539e-20	44.53	dual specificity phosphatase 9 [Source:MGI Symbol;...	[more]
Dusp7	2.051e-18	44.53	dual specificity phosphatase 7 [Source:MGI Symbol;...	[more]

BLAST of dual specificity protein phosphatase 12 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9JIM4\|DUS12_RAT	3.498e-43	34.56	Dual specificity protein phosphatase 12 OS=Rattus ...	[more]
sp\|Q9UNI6\|DUS12_HUMAN	1.899e-41	34.34	Dual specificity protein phosphatase 12 OS=Homo sa...	[more]
sp\|Q9D0T2\|DUS12_MOUSE	4.701e-40	33.00	Dual specificity protein phosphatase 12 OS=Mus mus...	[more]
sp\|O13632\|PVH1_SCHPO	4.378e-37	31.32	Tyrosine-protein phosphatase yvh1 OS=Schizosacchar...	[more]
sp\|Q9VWF4\|DUSK4_DROME	3.228e-30	26.41	Dual specificity protein phosphatase MPK-4 OS=Dros...	[more]

BLAST of dual specificity protein phosphatase 12 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3JIV5	2.875e-61	39.20	dual specificity protein phosphatase 12 OS=Lingula...	[more]
A0A210QP86	7.036e-56	37.87	Dual specificity protein phosphatase 12 OS=Mizuhop...	[more]
A0A5K3ETZ7	9.473e-55	39.30	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
K1QLY7	4.547e-54	37.29	Dual specificity protein phosphatase 12 OS=Crassos...	[more]
V3ZYI8	1.122e-53	35.43	Uncharacterized protein OS=Lottia gigantea OX=2251...	[more]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dusp12	1.850e-41	31.79	dual specificity phosphatase 12 [Source:NCBI gene;...	[more]
dusp12	8.871e-22	28.86	dual specificity phosphatase 12 [Source:NCBI gene;...	[more]
dusp12	2.306e-21	28.86	dual specificity phosphatase 12 [Source:NCBI gene;...	[more]
dusp6	3.190e-20	35.91	dual specificity phosphatase 6 [Source:NCBI gene;A...	[more]
dusp6	4.441e-20	35.91	dual specificity phosphatase 6 [Source:NCBI gene;A...	[more]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dusp7	1.193e-21	44.53	dual specificity phosphatase 7 [Source:ZFIN;Acc:ZD...	[more]
dusp22b	5.943e-19	34.62	dual specificity phosphatase 22b [Source:NCBI gene...	[more]
dusp6	4.163e-18	40.94	dual specificity phosphatase 6 [Source:ZFIN;Acc:ZD...	[more]
ENSPMAT00000006071.1	4.556e-18	39.34	pep scaffold:Pmarinus_7.0:GL479824:161791:175185:-...	[more]
dusp10	1.273e-16	43.31	dual specificity phosphatase 10 [Source:ZFIN;Acc:Z...	[more]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
YVH1	1.972e-29	28.92	Dual specificity protein phosphatase; regulates gr...	[more]
MSG5	1.386e-6	31.86	Dual-specificity protein phosphatase; exists in 2 ...	[more]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO34381	6.596e-51	39.10	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37000	1.278e-21	40.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34920	2.413e-21	39.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45432	8.546e-20	44.09	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35438	3.951e-18	34.68	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of dual specificity protein phosphatase 12 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dusp12	1.022e-45	32.41	dual specificity phosphatase 12 [Source:NCBI gene;...	[more]
dusp7	8.542e-20	40.13	dual specificity phosphatase 7 [Source:NCBI gene;A...	[more]
dusp6	1.920e-19	43.75	dual specificity phosphatase 6 [Source:NCBI gene;A...	[more]
ENSORLT00000014597.2	9.818e-19	43.41	dual specificity protein phosphatase 7 [Source:NCB...	[more]
si:ch211-203d1.3	4.276e-18	35.46	slingshot protein phosphatase 3 [Source:NCBI gene;...	[more]

BLAST of dual specificity protein phosphatase 12 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000014789.1	0.000e+0	100.00	SMESG000014789.1	[more]
SMESG000001338.1	5.890e-44	34.98	SMESG000001338.1	[more]
SMESG000078269.1	3.375e-18	35.66	SMESG000078269.1	[more]
SMESG000070817.1	1.841e-17	39.84	SMESG000070817.1	[more]
SMESG000035381.1	5.555e-16	39.29	SMESG000035381.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30022703 ID=SMED30022703|Name=dual specificity protein phosphatase 12|organism=Schmidtea mediterranea sexual|type=transcript|length=1254bp
TTGGAATAATTAAAATAAAATTGTTTAAATATTATATTGTAAAATGAATT
AATTTTAATCATGAAAGAAATAATATCAAATTTATGGCTTGGATCATACG
AAGATGCATCAAATGTAGATTTGTTGAAATCATTGCAAATAAAGTACATA
TTAACAGTAATGGATAGTCCATTGTTACATAAAATGGAAGACTTTAATTA
CAAATTTATTAAAGCTTATGATGTTCCAAACCAAGACCTTATTTCTTATT
TCGATGAAACCAGTGAATTCATTGAAAATGGTAGAAAATTTGGTGGAGTT
CTAATTCATTGTCTTGCCGGAATTTCAAGAAGTGGAACTATTTTAACAGC
TTATATAATGAAACATTTTAAAATTGATCCAAACGATGCAATTGAGAAAA
TTAAAGAAAAGTCATTTATATGCCCAAATGATGGATTTATGAAACAATTA
AAGATATATTTCAACATGAAATGCACCGGTGATTACAAAAGCGATGAGTA
CAAACAATTTATCCGTCTATTTTCTCCAGATGATATCAATAAATGTACAA
ATACAGTTTCGCAAGCTCAATTTAATTTATCAAAATCTTCTACTGATTTA
ATCCAATTCAAATGCAAAAAGTGCAGATTTTTGTTATTCGACAATTCAAG
TGTTGTCGAGCACAGTAAAATGAAAGCTTCGAAAACAATAACCGAGAACA
CTATTTGCAACGAGGAAATATTTATTGAAGCTCTTCCTTGGATTGATAGC
AGCAGTGCAAATGGTGGAAAGGTTAACTGTCCGAAATGTGCTTGCAAATT
GGGCTCCTATACCTGGGTCGGAGAACGATGCGTTTGTGGCAATTGGGTCG
TGCCTGCATTTCACATTGCCAAGCAAAAGGTTGATCCAGTCAAATCGATG
AGTTTTTAATCACTTTCCGAAGAATTAAAAATTTATCAAGGAAACATTTA
GAATAAAAAACGACTTTGATAATATTCTTAAGTTTAGATTTATATCGATT
TTTAATTATAGATTTTCTATTGTATTGTCGATCGATTTTTAACCTGTTTT
GTGTAGATTTTTATGGTCATTTTTGTTTTTTATCGGATAGAGGGTTTTAT
TGGGCTTGTTGGTGGTTTTAAGGCGGTTTTGGATTGTAATTTGATAATTC
GTCGGTTTTCTGATAATTGGACGTCTTTAGTTTTTGGCGTTTATTTGGAT
AATATTTTTTAGTGCAAATGGATTCATGTTGGTTGTAATTCGCTTAGTTT
CGTT

protein sequence of SMED30022703-orf-1

>SMED30022703-orf-1 ID=SMED30022703-orf-1|Name=SMED30022703-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=283bp
MKEIISNLWLGSYEDASNVDLLKSLQIKYILTVMDSPLLHKMEDFNYKFI
KAYDVPNQDLISYFDETSEFIENGRKFGGVLIHCLAGISRSGTILTAYIM
KHFKIDPNDAIEKIKEKSFICPNDGFMKQLKIYFNMKCTGDYKSDEYKQF
IRLFSPDDINKCTNTVSQAQFNLSKSSTDLIQFKCKKCRFLLFDNSSVVE
HSKMKASKTITENTICNEEIFIEALPWIDSSSANGGKVNCPKCACKLGSY
TWVGERCVCGNWVVPAFHIAKQKVDPVKSMSF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0016787	hydrolase activity
GO:0008138	protein tyrosine/serine/threonine phosphatase activity
GO:0016791	phosphatase activity
GO:0004725	protein tyrosine phosphatase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR003595	Tyr_Pase_cat
IPR020422	TYR_PHOSPHATASE_DUAL_dom
IPR016278	DUSP12
IPR000340	Dual-sp_phosphatase_cat-dom
IPR029021	Prot-tyrosine_phosphatase-like
IPR016130	Tyr_Pase_AS
IPR000387	TYR_PHOSPHATASE_dom
IPR011528	NERD

Vocabulary: **biological process**
Term	Definition
GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR020422	Dual specificity protein phosphatase domain	SMART	SM00195	dsp_5	coord: 1..136 e-value: 2.2E-36 score: 136.9
IPR020422	Dual specificity protein phosphatase domain	PROSITE	PS50054	TYR_PHOSPHATASE_DUAL	coord: 1..130 score: 31.585
IPR003595	Protein-tyrosine phosphatase, catalytic	SMART	SM00404	ptp_7	coord: 41..190 e-value: 0.002 score: 19.4
IPR016278	Dual specificity protein phosphatase 12	PIRSF	PIRSF000941	DUSP12	coord: 1..282 e-value: 2.3E-70 score: 234.9
IPR000340	Dual specificity phosphatase, catalytic domain	PFAM	PF00782	DSPc	coord: 8..134 e-value: 9.9E-29 score: 99.8
IPR029021	Protein-tyrosine phosphatase-like	GENE3D	G3DSA:3.90.190.10		coord: 1..143 e-value: 4.9E-43 score: 148.7
IPR029021	Protein-tyrosine phosphatase-like	SUPERFAMILY	SSF52799	(Phosphotyrosine protein) phosphatases II	coord: 3..136
None	No IPR available	PANTHER	PTHR45848	FAMILY NOT NAMED	coord: 6..279
None	No IPR available	PANTHER	PTHR45848:SF2	DUAL SPECIFICITY PROTEIN PHOSPHATASE 12	coord: 6..279
None	No IPR available	CDD	cd14498	DSP	coord: 3..131 e-value: 1.91247E-52 score: 165.797
IPR016130	Protein-tyrosine phosphatase, active site	PROSITE	PS00383	TYR_PHOSPHATASE_1	coord: 82..92
IPR000387	Tyrosine specific protein phosphatases domain	PROSITE	PS50056	TYR_PHOSPHATASE_2	coord: 58..117 score: 14.169