Endothelin converting enzyme 1

Overview
NameEndothelin converting enzyme 1
Smed IDSMED30022629
Length (bp)2375
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Endothelin converting enzyme 1 (SMED30022629) t-SNE clustered cells

Violin plots show distribution of expression levels for Endothelin converting enzyme 1 (SMED30022629) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Endothelin converting enzyme 1 (SMED30022629) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Endothelin converting enzyme 1 (SMED30022629) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30022629

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 35

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30022629h1SMcG0010402 Contig5284uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30022629h1SMcG0010402 Contig5284newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30022629h1SMcG0019747 Contig5284uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30022629h1SMcG0019747 Contig5284newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30022629h1SMcG0010402 Contig868newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30022629h1SMcG0010402 Contig868uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30022629h1SMcG0020975 Contig868newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30022629h1SMcG0020975 Contig868uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
prepharyngeal regionSMED30022629h1SMcG0010402 SmedASXL_076945SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30022629h1SMcG0010402 SmedASXL_076945SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
prepharyngeal regionSMED30022629h1SMcG0010402 SmedASXL_017737SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30022629h1SMcG0010402 SmedASXL_017737SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
prepharyngeal regionSMED30022629h1SMcG0010402 SmedASXL_076946SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30022629h1SMcG0010402 SmedASXL_076946SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
prepharyngeal regionSMED30022629h1SMcG0010402 SmedASXL_076944SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30022629h1SMcG0010402 SmedASXL_076944SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0010402 Contig25580uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0010402 Contig25580newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0010402 Contig5284uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0010402 Contig5284newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0010402 Contig18452uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0010402 Contig18452newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0010402 Contig26914uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0010402 Contig26914newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0019747 Contig5284uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0019747 Contig5284newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0010402 Contig868newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0010402 Contig868uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0020975 Contig868newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022629h1SMcG0020975 Contig868uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
parapharyngeal regionSMED30022629h1SMcG0010402 dd_Smed_v6_14597_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30022629h1SMcG0010402 Contig868newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30022629h1SMcG0010402 Contig868uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30022629h1SMcG0020975 Contig868newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30022629h1SMcG0020975 Contig868uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Human
Match: ECE1 (endothelin converting enzyme 1 [Source:HGNC Symbol;Acc:HGNC:3146])

HSP 1 Score: 358.607 bits (919), Expect = 1.335e-111
Identity = 209/681 (30.69%), Postives = 346/681 (50.81%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGN--------DFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGIS--KTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            VC +E C  +   +   M+ + DPC DF SY CG   K   +  G + + +F+ +       +K LLE  STA+ S+ + KA +YY++CMN+    ++    ++E+ + +   N        +F+  L  +      S FFS+ V+ D+ N   N++ + +    L       +++ +++++  Y+ YM ++  +LG    +     + +IL     LA        + D E   +K++  ++Q   P+I+W+  +N +F    +++ E + +V +  EYL+    ++         R +L   + W ++    S       +A+E+FM    G K      WK CV  T + L   +G MFVK+ F    K     +I  IK A +  +  L WMD  T+ SA EK  AI + IGYP+ ++    L K +       + +  N + F  FS       + K  + D+W+M    VNAYY+P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  +T+C++ QY++Y +N +P+    T+GE+IADN G++ +Y A  + ++    + +LP + L+  QLFF+G  + WC++ T     + L  D HS  ++R+ G +SN  EFS+ F C     MN   KC VW
Sbjct:   82 VCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLE-NSTASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIF--YPVEINESEPIVVYDKEYLEQISTLINT-----TDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 754
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Human
Match: ECE1 (endothelin converting enzyme 1 [Source:HGNC Symbol;Acc:HGNC:3146])

HSP 1 Score: 358.221 bits (918), Expect = 1.782e-111
Identity = 209/681 (30.69%), Postives = 346/681 (50.81%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGN--------DFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGIS--KTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            VC +E C  +   +   M+ + DPC DF SY CG   K   +  G + + +F+ +       +K LLE  STA+ S+ + KA +YY++CMN+    ++    ++E+ + +   N        +F+  L  +      S FFS+ V+ D+ N   N++ + +    L       +++ +++++  Y+ YM ++  +LG    +     + +IL     LA        + D E   +K++  ++Q   P+I+W+  +N +F    +++ E + +V +  EYL+    ++         R +L   + W ++    S       +A+E+FM    G K      WK CV  T + L   +G MFVK+ F    K     +I  IK A +  +  L WMD  T+ SA EK  AI + IGYP+ ++    L K +       + +  N + F  FS       + K  + D+W+M    VNAYY+P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  +T+C++ QY++Y +N +P+    T+GE+IADN G++ +Y A  + ++    + +LP + L+  QLFF+G  + WC++ T     + L  D HS  ++R+ G +SN  EFS+ F C     MN   KC VW
Sbjct:   86 VCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLEN-STASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIF--YPVEINESEPIVVYDKEYLEQISTLINT-----TDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 758
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Human
Match: ECE1 (endothelin converting enzyme 1 [Source:HGNC Symbol;Acc:HGNC:3146])

HSP 1 Score: 358.607 bits (919), Expect = 1.841e-111
Identity = 209/681 (30.69%), Postives = 346/681 (50.81%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGN--------DFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGIS--KTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            VC +E C  +   +   M+ + DPC DF SY CG   K   +  G + + +F+ +       +K LLE  STA+ S+ + KA +YY++CMN+    ++    ++E+ + +   N        +F+  L  +      S FFS+ V+ D+ N   N++ + +    L       +++ +++++  Y+ YM ++  +LG    +     + +IL     LA        + D E   +K++  ++Q   P+I+W+  +N +F    +++ E + +V +  EYL+    ++         R +L   + W ++    S       +A+E+FM    G K      WK CV  T + L   +G MFVK+ F    K     +I  IK A +  +  L WMD  T+ SA EK  AI + IGYP+ ++    L K +       + +  N + F  FS       + K  + D+W+M    VNAYY+P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  +T+C++ QY++Y +N +P+    T+GE+IADN G++ +Y A  + ++    + +LP + L+  QLFF+G  + WC++ T     + L  D HS  ++R+ G +SN  EFS+ F C     MN   KC VW
Sbjct:   95 VCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLEN-STASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIF--YPVEINESEPIVVYDKEYLEQISTLINT-----TDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 767
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Human
Match: ECE1 (endothelin converting enzyme 1 [Source:HGNC Symbol;Acc:HGNC:3146])

HSP 1 Score: 358.221 bits (918), Expect = 2.524e-111
Identity = 209/681 (30.69%), Postives = 346/681 (50.81%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGN--------DFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGIS--KTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            VC +E C  +   +   M+ + DPC DF SY CG   K   +  G + + +F+ +       +K LLE  STA+ S+ + KA +YY++CMN+    ++    ++E+ + +   N        +F+  L  +      S FFS+ V+ D+ N   N++ + +    L       +++ +++++  Y+ YM ++  +LG    +     + +IL     LA        + D E   +K++  ++Q   P+I+W+  +N +F    +++ E + +V +  EYL+    ++         R +L   + W ++    S       +A+E+FM    G K      WK CV  T + L   +G MFVK+ F    K     +I  IK A +  +  L WMD  T+ SA EK  AI + IGYP+ ++    L K +       + +  N + F  FS       + K  + D+W+M    VNAYY+P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  +T+C++ QY++Y +N +P+    T+GE+IADN G++ +Y A  + ++    + +LP + L+  QLFF+G  + WC++ T     + L  D HS  ++R+ G +SN  EFS+ F C     MN   KC VW
Sbjct:   98 VCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLE-NSTASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIF--YPVEINESEPIVVYDKEYLEQISTLINT-----TDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 770
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Human
Match: ECE2 (endothelin converting enzyme 2 [Source:HGNC Symbol;Acc:HGNC:13275])

HSP 1 Score: 354.369 bits (908), Expect = 3.107e-110
Identity = 204/680 (30.00%), Postives = 350/680 (51.47%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDF----ELNLIKLLKSGLGS----RFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKT-YENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
             C TE C ++  ++ + +++   PC+DF  + CG   +   +  G++ +++F  +       LK LLE  +  + S+ + K   +Y SC+  E   ++    + ++ ++I   N      + N +++LK+  G+     FF++ ++ D+ +   N++ + +    L       + +++++++ +Y+ YM+++  +LG   T     + ++L+L I+LA        + D EK  +K+SI ++Q   PS+ W+  ++  F  + ++L + + +V + ++YL    +++     +R +  IL   L W ++    S        A E+ +    G K      W+ C+  T   L   +G++FVK+ F    K+  E MI  I+ A +  +  L WMD  T+ +A EK  AI   IG+PD ++    L   Y   E+S ++F  N L    FS +     + K  S D+W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D +G LR WW   S   + + T C+  QY  Y +N + L   QT+GE+IADN G++ +Y A  + L    E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  ++R+ G +SN  +F + F C     MN  + C VW
Sbjct:   64 TCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLS--FLLSPLELSDSEPVVVYGMDYLQQVSELI-----NRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 736
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Celegans
Match: nep-2 (Neprilysin-2 [Source:UniProtKB/Swiss-Prot;Acc:O44857])

HSP 1 Score: 293.893 bits (751), Expect = 6.601e-88
Identity = 198/694 (28.53%), Postives = 337/694 (48.56%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQA--KAAIYYQSCMNKESRNKISHPIILEVAKEI----SNGNDFELNL-IKLLKSGLGSRF-----FSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENL-IDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVF----ENTGIKLKEDD--KLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWA-VISSLVSLGSNALIEANEEFMSESLGVKGKQE-EWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVIN--NKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLT--LPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            VC +  C K    +   MN S DPCDDF  + CG   K + I     S  +F  +   +   LK+LL++       +  A  KA  +Y  C+N+            EV K      S G+  + +  I++L + + ++F     F   V  D  N + ++L I +P   L       +  + + +  +Y++ ++ VL +L   +T   L   EI+     LA    +   + D  +   K+++ +M++  P  +W    N +F    E  G ++  DD  ++V +  E+L    + L V +     R I+   LEW     +++    +       +F  ++L +   Q+  W  CV   +S +      ++VK+ F    K+ +E MI  I  +  +++ +  W+   TK +A +K+  ++ KIGYPD L     +  +Y   ++   ++     +F E    + L+ + + +  + W  G+  VNA+Y+P +NEI+FPA IL+  FY    P + N+GGIGVVIGHEI HGFD +G  +D+ G +R+WW  ++  ++  K QCI  QY+SYV++  N  +    T GE+IADN G++ +Y  A  K E R      LP V L+ +QLFF+   + WC  +       +L+   HS    R+ GP+SN  +F+K +NC+    MN ++KC VW
Sbjct:   52 VCLSPGCIKTASVILSSMNSSVDPCDDFYEFACGQWIKGHPIPDDAPSVSNFENLGQDLEFALKELLDENDEPYDYETSAVGKAKYFYNLCLNESEILDNWRTTFDEVVKSFGGWPSLGHQMKPDASIEMLYADMVAKFKADSLFKATVQPDDKNSQRHVLLIDQPQLNLFARDFYVAAENEERM--AYLQLIRDVLILLDADRTRATLDAKEIIDFETALANITMADEHRHDIAELYTKITLGEMRRSLPHFNWPLFFNRMFKDLHEKNGKRITFDDNTEVVVYGYEFL----RRLDVLIPQYDNRLIVNY-LEWCWFFKTMLRDLPDPFALTIFKFY-KTLNIMNVQKVRWHGCVTRINSLMPMATSAIYVKNHFDHEAKQQVEEMISLIMESFVDLLLSEDWLTKETKQTAKQKVNEMKRKIGYPDYLNDPAAVNNEYKTFKVYPGHYYQTKFSFYEQYQRDVLERITEAVDRERWVAGAALVNAFYSPNTNEIIFPAGILQPVFYSKDFPSSMNFGGIGVVIGHEITHGFDDRGRLYDNLGNIRQWWDNATISKFEHKAQCIEKQYSSYVLDQINMQINGKSTKGENIADNGGLKQAY-RAYKKYEKRHSRPPRLPGVNLTHDQLFFLNYAQIWCGTMNDKEAIRKLRTSEHSPGPIRVKGPLSNSYDFAKAYNCEPGSQMNPREKCRVW 736
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Celegans
Match: nep-11 (Neprilysin-11 [Source:UniProtKB/Swiss-Prot;Acc:O16796])

HSP 1 Score: 294.278 bits (752), Expect = 3.760e-87
Identity = 204/706 (28.90%), Postives = 333/706 (47.17%), Query Frame = 3 
Query:  246 EGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEIS-------NGNDFELNLIKLLKSGLGSR-------FFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRD---SESSSKEIIASYIKYMKKVLNILGISKTYENL----------IDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLE-YLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYL--TFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVI--NNKPLPSLQTVGEDIADNAGMRMSYFAANSKL-EVREKLTLPRV-ALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            E +VC T  C +        MN S DPCDDF  + CG  +  + I      F +F      V   L+ LLE Q     S+    A   Y+SCMNK   +++    + E   E+        N +  + N   LL   + SR       FF + +  D+ N   N L I + T  L  GT RD   + +     + +Y KY++++ ++L   KT  NL          I++I+   I LAK + +  ++ +  +  NK  I+D+    P + W+     +  +    L  ++  +      YL    +++     ++    +L   + W V+ S V        +  ++F+    G +     WK C Q+ S+ L    G ++V++ FQ S K +   MI +++ +  +++    WMD  TK+ A+EK  ++ + IGYPD       L K+Y    +S ++     +  + +   + E+ K + K     E+ +    VNA+Y+P  N I FPA IL+ PF+    P   NYG IG VIGHEI HGFD QGS++D  G L  WW++SS + + ++ +CI+ QY +Y +   N  +    T GE+IADN G++ ++ A    + E  E+  LP +   + EQ+FFV     WC    +     Q+  D HS   +R+ G +SNM  F+ V+ C RN  +N   KC+VW
Sbjct:  157 EPEVCSTPGCVRAATHFLNAMNTSVDPCDDFFEFACGQWNDQHPIPDDMYGFGTFAYAREQVRQQLRVLLE-QEVVTESESINMARATYRSCMNKTQLDELMTGPLFETLTELGEWPLLQENWDKTKFNFTSLL---VNSRRDYGVDVFFQLYIYADSKNTSRNTLFIDQSTLALGRGT-RDYYLNTTLFSSHMTAYRKYLRQIAHLL---KTDGNLTRSESEMNADIEKIIDFEIELAKIIVAEDERRNNTRLYNKRQIQDLYNLLPQVDWVPFFQSIAPSDLTHLFHNETEIIICEIEYLQHVSELI-----EKTDVGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGAIYVQAHFQESDKHEALRMIMHLRNSFADLVRQNDWMDEETKAVAIEKANSMINNIGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMKKSVVWMQSREFQK-LTKPFDKHEFDISPAVVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFDTRRRCIVEQYGNYTVPKTNFRVNGKLTQGENIADNGGVKEAFQAYQKYVTENGEEPRLPGLQQYTNEQIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVYKCPRNAPVNPDHKCIVW 848
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Celegans
Match: nep-1 (Neprilysin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q18673])

HSP 1 Score: 280.026 bits (715), Expect = 1.206e-82
Identity = 206/698 (29.51%), Postives = 324/698 (46.42%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEIS--------NGNDFELNLIKLLKSGLGSR----FFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRD---SESSSKEIIASYIKY----MKKVLNILGIS---KTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRV-INEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYL-TFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLP--SLQTVGEDIADNAGMRMSYFAANSKLEVR--EKLTLPRV-ALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            V ++E  ++    L K +N S DPCDDF  Y C      + I     S+  FT     V   ++ L E  ++   S+  A     Y +CM+ E  N +    +LE  K              +   +L KLL + + SR    FF    A+D+ N    +L+  + +  L   T RD    E   ++ + +Y KY    ++      G++      E+ +DEI+      A+ L +  D+ +  K  N     D+++    I W ++ ++         LK +  ++   +EYL     +L+          IL   L WA   S          +  +EF  +  G K +Q  WK CV      L    G+M+V+  F  + K     MI  ++ A +N++    WMD+ TK  ALEK   +  +IGYPD ++++  L   Y   E +  +     +   +++    Y + + + ++  E+   +  VNA+Y+P  N I FPA IL+ PF+D   P   NYGGIG VIGHEI HGFD  G +FD+ G LR+WW  ++  ++  +TQCII QYA   +    L      T GE+IADN G++ ++ A  S LE    ++  LP+  +L+ EQLFFVG  + WC   T       L  D HS    R+N  ++N PEF++ F C     MN  K+C+VW
Sbjct:   63 VGDSEGYQEASRLLQKSLNLSLDPCDDFFEYACRAWVDSHPIPDDLTSYSQFTATREKVLAEMRKLYEDNTSIPTSKSIALIKQIYNTCMDTEKHNAVGARDLLEKIKTYGYWPMVHNEKWRESTFDLTKLLSNTIQSRDVSVFFDFGPAEDSRNVSRRLLSFDQGSLGLGYST-RDYYLDEKKYEKQMKAYRKYTIGKVRYYTEDAGMAVNESKIESDVDEIIAFEKEWAQILVAEEDRRNYTKLYNVRRFDDLKEYMSIIDWKKLTLSTTPFLVHSYLKTNPSIIISDVEYLQKMNTLLQNTDPRIVTNYIL---LRWA--GSWSQEIGKKYEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKLSYASGSMYVRKYFDANAKNTTLDMITDLQEAFRNMMHANDWMDAETKKYALEKADQMLKQIGYPDFILNDEKLDDWYKGLEGAPEDSFSQLVEKSIQWRNNFYYRRLLEPVNRFEFISSAAVVNAFYSPTRNAIAFPAGILQQPFFDARFPKALNYGGIGAVIGHEITHGFDDTGRQFDNVGNLRDWWDNTTSSKFNERTQCIIEQYADVKLRGTDLRINGKLTQGENIADNGGIKQAFKAYKSYLEKHGGQEARLPQFESLTNEQLFFVGYAQVWCGAKTPETKTLLLLTDPHSPETARVNTVLTNQPEFAEAFKCPAGSPMNPTKRCVVW 754
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Celegans
Match: nep-21 (Neprilysin-21 [Source:UniProtKB/Swiss-Prot;Acc:Q22523])

HSP 1 Score: 263.848 bits (673), Expect = 1.352e-76
Identity = 174/716 (24.30%), Postives = 330/716 (46.09%), Query Frame = 3 
Query:  216 IAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISN------------GNDFELNLIKLLK-SGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKE-IIASYIKYMKKVLNILGISKTY-ENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGV--KGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQK-KDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYA----PTEMSGNNFLGNYLTFLEFS------TEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQY--ASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVA----LSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +A+    K +   VC +  C +L   L + +N   +PC+DF  + CGN     ++   +    + + + S +   +K +L+   +AN       A  YYQ C+++E         + ++AK I               + +E  +  +L  +G+ +    + V  D +N   +++ + +P +    G+     S + + ++ +Y   MK     LG      E  ++E ++  ++L         + DPE+  N+  +  ++  FP I++ + +  VF+   + L  +  ++   ++Y      +L+        + +L   + W ++         +  E   +F +   G+      + W+ CV ++   +   VG +FV++ F+  +  K +  +  Y+K      +  L WMD  T+  A+ K   I +K G+P  L ++T++ K +     P E         YL  L         TEE L+ + + +    W     +V+AYY P +NE++FPA I++FPF  +G+P    YG +G VIGHE+ H FD QG ++D  G L +WW   + ++++ KT+C + QY     V  +  L    ++GE+IADN G++ ++ A  +       ++ P +      + +Q+FF+    +WC++V   +    +  DVH+  KYR   P+ N PEF+K F C     MN ++KC VW
Sbjct:   72 VAVDRSAKNHNDVVCTSRECVRLAGFLAENLNSKINPCEDFYEFACGNYGLNKNLPANKPLRHTISDVQSRLNKQVKSMLQSPISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRIGGWPTLEGDKWQEWSHSWEEQIALVLNLTGVNAVILEMAVTHDPSNSSRSVIELDQPKWG--AGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAIAEKEMNEAMEFELKLVNFSADDMVRRDPERGNNRFELWQLKSVFPFINFEKYLKTVFKEL-VALSPNHTVIVREIDYFVGIQHVLQ-----STPKRVLANYISWRLVQGFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFVENFFEKERAMKKMTELTSYLKNEFIKQLHVLDWMDEITRRRAISKANMIEYKSGFPMVLFNDTWMEKNWGMIIKPRE---------YLLHLTIRVKLVRFTEELLR-LDQPLDRSMWFQSPAQVDAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEKTRCFVRQYENVHVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAWKSNTTGISEPALPGFQNFTSQQMFFLAYANNWCSLVRPKHYIQIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPIGSPMNPERKCQVW 769
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Celegans
Match: nep-21 (Neprilysin-21 [Source:UniProtKB/Swiss-Prot;Acc:Q22523])

HSP 1 Score: 263.848 bits (673), Expect = 1.352e-76
Identity = 174/716 (24.30%), Postives = 330/716 (46.09%), Query Frame = 3 
Query:  216 IAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISN------------GNDFELNLIKLLK-SGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKE-IIASYIKYMKKVLNILGISKTY-ENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGV--KGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQK-KDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYA----PTEMSGNNFLGNYLTFLEFS------TEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQY--ASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVA----LSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +A+    K +   VC +  C +L   L + +N   +PC+DF  + CGN     ++   +    + + + S +   +K +L+   +AN       A  YYQ C+++E         + ++AK I               + +E  +  +L  +G+ +    + V  D +N   +++ + +P +    G+     S + + ++ +Y   MK     LG      E  ++E ++  ++L         + DPE+  N+  +  ++  FP I++ + +  VF+   + L  +  ++   ++Y      +L+        + +L   + W ++         +  E   +F +   G+      + W+ CV ++   +   VG +FV++ F+  +  K +  +  Y+K      +  L WMD  T+  A+ K   I +K G+P  L ++T++ K +     P E         YL  L         TEE L+ + + +    W     +V+AYY P +NE++FPA I++FPF  +G+P    YG +G VIGHE+ H FD QG ++D  G L +WW   + ++++ KT+C + QY     V  +  L    ++GE+IADN G++ ++ A  +       ++ P +      + +Q+FF+    +WC++V   +    +  DVH+  KYR   P+ N PEF+K F C     MN ++KC VW
Sbjct:   72 VAVDRSAKNHNDVVCTSRECVRLAGFLAENLNSKINPCEDFYEFACGNYGLNKNLPANKPLRHTISDVQSRLNKQVKSMLQSPISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRIGGWPTLEGDKWQEWSHSWEEQIALVLNLTGVNAVILEMAVTHDPSNSSRSVIELDQPKWG--AGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAIAEKEMNEAMEFELKLVNFSADDMVRRDPERGNNRFELWQLKSVFPFINFEKYLKTVFKEL-VALSPNHTVIVREIDYFVGIQHVLQ-----STPKRVLANYISWRLVQGFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFVENFFEKERAMKKMTELTSYLKNEFIKQLHVLDWMDEITRRRAISKANMIEYKSGFPMVLFNDTWMEKNWGMIIKPRE---------YLLHLTIRVKLVRFTEELLR-LDQPLDRSMWFQSPAQVDAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEKTRCFVRQYENVHVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAWKSNTTGISEPALPGFQNFTSQQMFFLAYANNWCSLVRPKHYIQIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPIGSPMNPERKCQVW 769
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Fly
Match: Nep3 (gene:FBgn0031081 transcript:FBtr0307554)

HSP 1 Score: 352.058 bits (902), Expect = 3.529e-109
Identity = 203/685 (29.64%), Postives = 355/685 (51.82%), Query Frame = 3 
Query:  258 CETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESR-----NKISHPIILE-----VAKEISNGNDFEL-NLIKLLKSGLG-SRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSS-KEIIASYIKYMKKVLNILGI--SKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREK--LTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            C  + C     E+ K ++ + DPCDDF  Y C    K   I  G++++ +F ++       ++++LEK + + +S  + KA +YY+SC++ +        K  + ++L+     V K   N  ++ + + +K+L +    +  F   + +D  N   +++ I +    L      ++++ + ++++  YI+YM KV  +LG   S     +I  ++    +LA     + D+ + E   + + +R + K  P ++W    +   +  G ++ +D+ +V ++ ++L +   I+       + +  L   L W  + +L S  S    +A +      +G  G +E W+ CV  T++ +   VG +FV+  F    K   E MI  I+ A K  ++NLTW+D  T+  A+EK   I   IG+PD ++    L KKYA   ++ N +  N +    ++ +  LK + + ++   W M  Q VNAYY P  N+IVFPA IL+ PF+DI  P + N+G +GVV+GHE+ H FD QG ++D  G +  WW   S + +  K++CI  QY+ Y +N + L   QT+GE+IADN G++ +Y A       R+   L LP + L+  QLFFV   + WC+  T      Q+++D HS  ++R+ G +SNM EF++VF C   K MN  +KC VW
Sbjct:  103 CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIG-VINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Fly
Match: Nep3 (gene:FBgn0031081 transcript:FBtr0070000)

HSP 1 Score: 352.058 bits (902), Expect = 3.529e-109
Identity = 203/685 (29.64%), Postives = 355/685 (51.82%), Query Frame = 3 
Query:  258 CETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESR-----NKISHPIILE-----VAKEISNGNDFEL-NLIKLLKSGLG-SRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSS-KEIIASYIKYMKKVLNILGI--SKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREK--LTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            C  + C     E+ K ++ + DPCDDF  Y C    K   I  G++++ +F ++       ++++LEK + + +S  + KA +YY+SC++ +        K  + ++L+     V K   N  ++ + + +K+L +    +  F   + +D  N   +++ I +    L      ++++ + ++++  YI+YM KV  +LG   S     +I  ++    +LA     + D+ + E   + + +R + K  P ++W    +   +  G ++ +D+ +V ++ ++L +   I+       + +  L   L W  + +L S  S    +A +      +G  G +E W+ CV  T++ +   VG +FV+  F    K   E MI  I+ A K  ++NLTW+D  T+  A+EK   I   IG+PD ++    L KKYA   ++ N +  N +    ++ +  LK + + ++   W M  Q VNAYY P  N+IVFPA IL+ PF+DI  P + N+G +GVV+GHE+ H FD QG ++D  G +  WW   S + +  K++CI  QY+ Y +N + L   QT+GE+IADN G++ +Y A       R+   L LP + L+  QLFFV   + WC+  T      Q+++D HS  ++R+ G +SNM EF++VF C   K MN  +KC VW
Sbjct:  103 CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIG-VINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Fly
Match: Nep3 (gene:FBgn0031081 transcript:FBtr0307555)

HSP 1 Score: 352.058 bits (902), Expect = 3.529e-109
Identity = 203/685 (29.64%), Postives = 355/685 (51.82%), Query Frame = 3 
Query:  258 CETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESR-----NKISHPIILE-----VAKEISNGNDFEL-NLIKLLKSGLG-SRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSS-KEIIASYIKYMKKVLNILGI--SKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREK--LTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            C  + C     E+ K ++ + DPCDDF  Y C    K   I  G++++ +F ++       ++++LEK + + +S  + KA +YY+SC++ +        K  + ++L+     V K   N  ++ + + +K+L +    +  F   + +D  N   +++ I +    L      ++++ + ++++  YI+YM KV  +LG   S     +I  ++    +LA     + D+ + E   + + +R + K  P ++W    +   +  G ++ +D+ +V ++ ++L +   I+       + +  L   L W  + +L S  S    +A +      +G  G +E W+ CV  T++ +   VG +FV+  F    K   E MI  I+ A K  ++NLTW+D  T+  A+EK   I   IG+PD ++    L KKYA   ++ N +  N +    ++ +  LK + + ++   W M  Q VNAYY P  N+IVFPA IL+ PF+DI  P + N+G +GVV+GHE+ H FD QG ++D  G +  WW   S + +  K++CI  QY+ Y +N + L   QT+GE+IADN G++ +Y A       R+   L LP + L+  QLFFV   + WC+  T      Q+++D HS  ++R+ G +SNM EF++VF C   K MN  +KC VW
Sbjct:  103 CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIG-VINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Fly
Match: Nep1 (gene:FBgn0029843 transcript:FBtr0343930)

HSP 1 Score: 339.732 bits (870), Expect = 5.715e-104
Identity = 205/692 (29.62%), Postives = 349/692 (50.43%), Query Frame = 3 
Query:  243 YEGK--VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNL-------IKLLKSGLGSRF-----FSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGIS-KTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVIN--NKPLPSLQTVGEDIADNAGMRMSYFAAN--SKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +EG+  +C T+ C +    L   M+ ++DPC+DF  Y CG  +K++ I   ++S  +F  +S      L+ +LE+      ++   KA  +++SCM+     KI    + +V + +      E N        ++ L   L   +       + V  D  N   NIL + +  + L        ESS+ +  A Y +YM +V  +LG    T    +++++    +L       AD+ D      K+ + ++Q+  P + W   +       GI L+ED+ LV + L YL    KIL         R ++   + W ++ SL+S   +       EF    +G++ ++  W +CV+ T+  L   VG +F++  F    K+    MI  I+AA   ++    WMD  T++ A EK  ++  +IGYP+ L + T L ++Y    +  +NF+ N L+ L++ +E+ L+ + + +  ++W      VNA+YNP  N+IVFPA IL+  FY    P + NYGGIGVVIGHEI HGFD +G +FD +G + +WW  ++ + +  +TQC+I+QY+ Y IN  +  +    T GE+IADN G++ ++ A      L  RE+  LP + ++ +QLFF+   + WC  +       +++  VHS    R+ GP+SN  +F+  + C     MN  +KC VW
Sbjct:  166 HEGQDNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRRA-YHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELVPEVQWQEYLQAAL-GPGIPLQEDEPLVTYGLHYLTEMGKILA-----HTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQ-QLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Fly
Match: Nep1 (gene:FBgn0029843 transcript:FBtr0070873)

HSP 1 Score: 339.732 bits (870), Expect = 5.715e-104
Identity = 205/692 (29.62%), Postives = 349/692 (50.43%), Query Frame = 3 
Query:  243 YEGK--VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNL-------IKLLKSGLGSRF-----FSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGIS-KTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVIN--NKPLPSLQTVGEDIADNAGMRMSYFAAN--SKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +EG+  +C T+ C +    L   M+ ++DPC+DF  Y CG  +K++ I   ++S  +F  +S      L+ +LE+      ++   KA  +++SCM+     KI    + +V + +      E N        ++ L   L   +       + V  D  N   NIL + +  + L        ESS+ +  A Y +YM +V  +LG    T    +++++    +L       AD+ D      K+ + ++Q+  P + W   +       GI L+ED+ LV + L YL    KIL         R ++   + W ++ SL+S   +       EF    +G++ ++  W +CV+ T+  L   VG +F++  F    K+    MI  I+AA   ++    WMD  T++ A EK  ++  +IGYP+ L + T L ++Y    +  +NF+ N L+ L++ +E+ L+ + + +  ++W      VNA+YNP  N+IVFPA IL+  FY    P + NYGGIGVVIGHEI HGFD +G +FD +G + +WW  ++ + +  +TQC+I+QY+ Y IN  +  +    T GE+IADN G++ ++ A      L  RE+  LP + ++ +QLFF+   + WC  +       +++  VHS    R+ GP+SN  +F+  + C     MN  +KC VW
Sbjct:  166 HEGQDNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRRA-YHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELVPEVQWQEYLQAAL-GPGIPLQEDEPLVTYGLHYLTEMGKILA-----HTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQ-QLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Zebrafish
Match: ece2b (endothelin converting enzyme 2b [Source:ZFIN;Acc:ZDB-GENE-131120-140])

HSP 1 Score: 378.637 bits (971), Expect = 2.460e-119
Identity = 212/682 (31.09%), Postives = 359/682 (52.64%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFE-------LNLIKLLKSGLGSR-FFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDS--ESSSKEIIASYIKYMKKVLNILGISK-TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C TE C  +  ++ + +++SADPC DF  Y CG   +   +  G++ + +F  I       LK LLE  +  + S+ + K   YY SC+N++   ++    ++++  +I   N  E       L+++K++     ++ FF++ V+ D  N   N++ + +    L     RD     ++++++ +Y+ YM ++  +LG  K +    + +IL     LA       ++ D EK  +K++I D+Q   P+I W+  +N V   + ++L + + +V ++ EY+    +++     ++    +L   + W ++    S        A ++ +    G K      W+ C+  T  TL   +G +FVK+ F    K+  E MI+ I+ A K  +++L WMD  T+ +A +K  AI   IG+PD ++    L   Y   E++ +NF  N + F  FS       + K  + D+W+M    VNAYY P  N IVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + + ++T+C+++QY  Y IN + +   QT+GE+IADN G++ +Y A  S ++   E+  LP V L+ +QLFFVG  + WC++ T     + L  D HS  KYR+ G +SN PEF++ F C    +MN   +C VW
Sbjct:   94 ICLTEACVTVASKIVEALDRSADPCQDFYQYACGGWVRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAERKTQSYYLSCLNEQRIEELGAQPLMDLITKIGGWNITESWDKENFLDVLKIISGPYRAQPFFTVSVSVDPKNSNSNVIQVDQSGLFLPS---RDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTRGQMQQILDFETALANITVPQDERRDEEKIYHKITIADLQVLAPAIEWLDYLNSVL--SPLELNDTEPVVVYAKEYMQQVSELI-----NKTDHSLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVKATFDKQSKEIAEGMINEIRTAFKGALDDLKWMDEQTRQAAKDKADAIYDMIGFPDFILDSKELDDVYDGYEVTEDNFFQNMINFYNFSARVMADQLRKPPNRDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAQDHPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRSWWQNSSVEAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVQKNGEEKRLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPEFAEHFQCPLGSSMNSGHRCEVW 765
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Zebrafish
Match: ece1 (endothelin converting enzyme 1 [Source:ZFIN;Acc:ZDB-GENE-061110-100])

HSP 1 Score: 348.206 bits (892), Expect = 5.734e-108
Identity = 205/700 (29.29%), Postives = 368/700 (52.57%), Query Frame = 3 
Query:  204 VVGLIAILSLCKLYEGK---VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISN--------GNDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISK-TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFA-ANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            V   I I+SL   Y+     +C +E C  +   +   +++S DPC DF ++ CG   +   +  G++ +  F+ +       +K+LLE  S  + S+ + KA  YYQ+CMN+    ++    + ++  +            ++F+  L  +  +   S FF++ V+ D+ +   NI+ + +    L       +++++++ + +Y+ ++ ++  +LG S+ T + +++EI++    LA       ++ D EK   K+  +++    P+I W+  ++ VF    ++L + + +V ++ EYL    +++         + +L   +   V+  +VS+      +A + F+    G K      WK CV  T S L   +G +FVK+ F    K  +E M+  IK A ++ ++ ++WMD  TK +A EK  AI + +GYP  +++   L K +   ++  + +  N + +  FS       + K  + D+W+M    VNAYYNP  NE+V PA I + PFY+   P   N+GGIGVV+GHE+ H FD QG K+D  G L +WW  SS + +  +TQC++ QY++Y INN+PL    T+GE+IADN G+  +Y A  N   +  E+ +LP + ++  QLFFVG  + WC++ T     + +  D HS  ++R+ G +SN  EFS+ F C  +  MN ++KC +W
Sbjct:   60 VALFICIMSLGLHYKESHPGLCLSEPCVSVASAVLGSLDRSVDPCQDFYNFACGGWMRKNPLPEGKSRWGPFSNLWEHNMAVMKNLLENTSMKSLSRAEQKAQWYYQACMNESKIEELGAKPLQDLINQTGGWGLKGPWEKDNFQEVLRIVSANFRTSPFFTVFVSTDSKSSNSNIIQVDQSGLGLPSREYYLNKTANEKYLNAYLNFLVELGVLLGGSQDTSQKMMEEIIEFETTLANITVPQVERRDEEKIYYKIQAKELATLAPAIDWMPFLSSVF--APVELNDSEPVVVYAKEYLQKVSELIS-----NTNKSVLNNYMIMKVVRKMVSILDQKFQDAEQRFLEVMYGTKKSCMPRWKLCVSDTDSALGFALGALFVKATFSEDSKAFVEDMVSEIKWAFEDSLKTVSWMDPETKKAAKEKADAIYNMVGYPKFIMNPKELDKVFNDFDVVSDLYFQNVMNYYNFSARVTADQLRKAPNRDQWSMTPPTVNAYYNPTKNEMVLPAGIFQAPFYNHAWPKAMNFGGIGVVMGHELTHAFDDQGRKYDKDGNLAKWWQNSSVEAFQHQTQCMVEQYSNYSINNEPLNGKHTLGENIADNGGLNAAYKAYVNWIKKNGEEASLPALGMNNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSHEFSEHFGCKADSPMNPKRKCELW 752
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Zebrafish
Match: ece1 (endothelin converting enzyme 1 [Source:ZFIN;Acc:ZDB-GENE-061110-100])

HSP 1 Score: 348.206 bits (892), Expect = 5.734e-108
Identity = 205/700 (29.29%), Postives = 368/700 (52.57%), Query Frame = 3 
Query:  204 VVGLIAILSLCKLYEGK---VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISN--------GNDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISK-TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFA-ANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            V   I I+SL   Y+     +C +E C  +   +   +++S DPC DF ++ CG   +   +  G++ +  F+ +       +K+LLE  S  + S+ + KA  YYQ+CMN+    ++    + ++  +            ++F+  L  +  +   S FF++ V+ D+ +   NI+ + +    L       +++++++ + +Y+ ++ ++  +LG S+ T + +++EI++    LA       ++ D EK   K+  +++    P+I W+  ++ VF    ++L + + +V ++ EYL    +++         + +L   +   V+  +VS+      +A + F+    G K      WK CV  T S L   +G +FVK+ F    K  +E M+  IK A ++ ++ ++WMD  TK +A EK  AI + +GYP  +++   L K +   ++  + +  N + +  FS       + K  + D+W+M    VNAYYNP  NE+V PA I + PFY+   P   N+GGIGVV+GHE+ H FD QG K+D  G L +WW  SS + +  +TQC++ QY++Y INN+PL    T+GE+IADN G+  +Y A  N   +  E+ +LP + ++  QLFFVG  + WC++ T     + +  D HS  ++R+ G +SN  EFS+ F C  +  MN ++KC +W
Sbjct:   60 VALFICIMSLGLHYKESHPGLCLSEPCVSVASAVLGSLDRSVDPCQDFYNFACGGWMRKNPLPEGKSRWGPFSNLWEHNMAVMKNLLENTSMKSLSRAEQKAQWYYQACMNESKIEELGAKPLQDLINQTGGWGLKGPWEKDNFQEVLRIVSANFRTSPFFTVFVSTDSKSSNSNIIQVDQSGLGLPSREYYLNKTANEKYLNAYLNFLVELGVLLGGSQDTSQKMMEEIIEFETTLANITVPQVERRDEEKIYYKIQAKELATLAPAIDWMPFLSSVF--APVELNDSEPVVVYAKEYLQKVSELIS-----NTNKSVLNNYMIMKVVRKMVSILDQKFQDAEQRFLEVMYGTKKSCMPRWKLCVSDTDSALGFALGALFVKATFSEDSKAFVEDMVSEIKWAFEDSLKTVSWMDPETKKAAKEKADAIYNMVGYPKFIMNPKELDKVFNDFDVVSDLYFQNVMNYYNFSARVTADQLRKAPNRDQWSMTPPTVNAYYNPTKNEMVLPAGIFQAPFYNHAWPKAMNFGGIGVVMGHELTHAFDDQGRKYDKDGNLAKWWQNSSVEAFQHQTQCMVEQYSNYSINNEPLNGKHTLGENIADNGGLNAAYKAYVNWIKKNGEEASLPALGMNNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSHEFSEHFGCKADSPMNPKRKCELW 752
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Zebrafish
Match: mmel1 (membrane metallo-endopeptidase-like 1 [Source:ZFIN;Acc:ZDB-GENE-101112-2])

HSP 1 Score: 320.472 bits (820), Expect = 1.773e-97
Identity = 201/704 (28.55%), Postives = 347/704 (49.29%), Query Frame = 3 
Query:  246 EGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDS-FTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNK---ESRNKISHPII--------LEVAKEISNGNDFELNLIKLLKSGLGSRF-----FSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNIL----GISKTYENLID---EILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFP--SISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISET--YLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASY---VINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +  VC T  C      L + M+ S DPC +F  Y CG   + + ++P  +S  S F  +   +   LK +LE ++  +R +   KA   Y SCMN+   E R+  S P++          VA E+ NG   +   ++   + L  R+       + V  D  +    I+++ +P   +       S+ + K++  +Y+++M  +  I      +++  E +++   ++L+L   +A A     +++D     NK+++R+ Q+ F     +W R I  +  +  I ++ D+ +V +   YL+   ++L      +     LQ  L W +I   VS  S    +    +     G   ++  W+ CV+     ++  VG ++V+  F  + K+ +  +I  I+ A    +E L+WMD  +K  A EK  AI  +IGYPD ++ E    L ++YA    S  N+  N L  L  S ++  K + + + PD W +G+  VNA+Y+   N+IVFPA IL+ PF+        N+GGIG+VIGHEI HGFD  G  FD  G +  WW+  S + +  +++C++ QY  +   +   + +  + T+GE+IADN G+R +Y A    +E   E+  LP + ++ +QLFF+   + WC      Y    +K D HS  +YR+ G + N   FS+ F+C R   MN ++KC VW
Sbjct:   61 DSNVCTTPQCVTAAARLLQNMDPSVDPCQNFYQYACGGWIERH-VIPETSSLHSVFNILRDELEIVLKGVLEMENKDDR-EAFKKAKTLYSSCMNEILIEQRD--SQPLLRLIDSIGDWPVASEVWNGTSEQTWSLEDTLAVLNGRYNKKAVLEMFVWPDDRDSSRYIIHVDQPALGMPSRDYYLSDGNYKKVREAYLEFMVSMARIAREDRNLTQDEERVLEDMSQVLELETDIANATSPAEERNDITVLYNKMTLREAQQTFNLNGFNWTRYIQGIMSSVSISVQSDEPIVIYCSPYLEKLSEVLS-----KHSHRTLQNYLVWMLIMDRVSSMSRRFKDVRAHYRKALHGTTVEEARWRDCVRYVQGNMENAVGALYVRETFSGNSKRMVGELIKKIQEAYVETLEELSWMDEQSKVKAREKAMAISEQIGYPDHILEEENKKLDQEYAHLNFSEENYFENILENLAASAQKGHKKLREPVDPDMWIIGAAVVNAFYSHNRNQIVFPAGILQPPFFSEKQLQALNFGGIGMVIGHEITHGFDDHGRNFDKDGNMYNWWSNYSAERFEDQSKCMVEQYGRFSWKLAGGQNVSGITTLGENIADNGGVRQAYKAYVKWVEREGEEPRLPGLDMNHKQLFFLNFAQVWCGACRPEYAIQTIKTDPHSPLEYRVLGSLQNFEAFSEAFHCARGAPMNPEEKCRVW 755
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Zebrafish
Match: mmel1 (membrane metallo-endopeptidase-like 1 [Source:ZFIN;Acc:ZDB-GENE-101112-2])

HSP 1 Score: 320.472 bits (820), Expect = 2.491e-97
Identity = 201/704 (28.55%), Postives = 347/704 (49.29%), Query Frame = 3 
Query:  246 EGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDS-FTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNK---ESRNKISHPII--------LEVAKEISNGNDFELNLIKLLKSGLGSRF-----FSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNIL----GISKTYENLID---EILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFP--SISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISET--YLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASY---VINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +  VC T  C      L + M+ S DPC +F  Y CG   + + ++P  +S  S F  +   +   LK +LE ++  +R +   KA   Y SCMN+   E R+  S P++          VA E+ NG   +   ++   + L  R+       + V  D  +    I+++ +P   +       S+ + K++  +Y+++M  +  I      +++  E +++   ++L+L   +A A     +++D     NK+++R+ Q+ F     +W R I  +  +  I ++ D+ +V +   YL+   ++L      +     LQ  L W +I   VS  S    +    +     G   ++  W+ CV+     ++  VG ++V+  F  + K+ +  +I  I+ A    +E L+WMD  +K  A EK  AI  +IGYPD ++ E    L ++YA    S  N+  N L  L  S ++  K + + + PD W +G+  VNA+Y+   N+IVFPA IL+ PF+        N+GGIG+VIGHEI HGFD  G  FD  G +  WW+  S + +  +++C++ QY  +   +   + +  + T+GE+IADN G+R +Y A    +E   E+  LP + ++ +QLFF+   + WC      Y    +K D HS  +YR+ G + N   FS+ F+C R   MN ++KC VW
Sbjct:   71 DSNVCTTPQCVTAAARLLQNMDPSVDPCQNFYQYACGGWIERH-VIPETSSLHSVFNILRDELEIVLKGVLEMENKDDR-EAFKKAKTLYSSCMNEILIEQRD--SQPLLRLIDSIGDWPVASEVWNGTSEQTWSLEDTLAVLNGRYNKKAVLEMFVWPDDRDSSRYIIHVDQPALGMPSRDYYLSDGNYKKVREAYLEFMVSMARIAREDRNLTQDEERVLEDMSQVLELETDIANATSPAEERNDITVLYNKMTLREAQQTFNLNGFNWTRYIQGIMSSVSISVQSDEPIVIYCSPYLEKLSEVLS-----KHSHRTLQNYLVWMLIMDRVSSMSRRFKDVRAHYRKALHGTTVEEARWRDCVRYVQGNMENAVGALYVRETFSGNSKRMVGELIKKIQEAYVETLEELSWMDEQSKVKAREKAMAISEQIGYPDHILEEENKKLDQEYAHLNFSEENYFENILENLAASAQKGHKKLREPVDPDMWIIGAAVVNAFYSHNRNQIVFPAGILQPPFFSEKQLQALNFGGIGMVIGHEITHGFDDHGRNFDKDGNMYNWWSNYSAERFEDQSKCMVEQYGRFSWKLAGGQNVSGITTLGENIADNGGVRQAYKAYVKWVEREGEEPRLPGLDMNHKQLFFLNFAQVWCGACRPEYAIQTIKTDPHSPLEYRVLGSLQNFEAFSEAFHCARGAPMNPEEKCRVW 765
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Xenopus
Match: dhdds (dehydrodolichyl diphosphate synthase subunit [Source:Xenbase;Acc:XB-GENE-1002142])

HSP 1 Score: 365.925 bits (938), Expect = 2.342e-114
Identity = 212/680 (31.18%), Postives = 359/680 (52.79%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEIS----NGNDFELNLIKLLKSGLGS----RFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENL-IDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKL-EVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C +E C  +   +   +++  DPC DF  Y CG   +   +  G++ +++F  I       LK +LE  +  + S+ + K   +Y SC+ ++   ++    + ++ ++I     +GN    N + +LK+  G+     FFS+ V+ D+ +   NI+ + +    L       +++++ +++ +Y++YM  V  +LG S    ++ + +IL+    LA       ++ D EK  N+++I ++Q   P+  W+  +   F  + + L + + +V +  EYL    +++     +     +L   L W ++  + S   +   +A ++ +    G K      W+ C+  T  TL   +G++FVKS F  + K   E MI  I+ A +  +  LTWMD  T+ +A EK  AI   IG+PD ++    L + Y   E+S + F  N L F  FS +   + + K  + ++W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + + ++T+C++NQY SY +N + +   QT+GE+IADN G++ +Y A  S L +  E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  K+R+ G +SN  +F++ FNC +   MN  K C VW
Sbjct:   94 LCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYL--TFALSPLDLNDTEPVVVYGKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 766
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Xenopus
Match: dhdds (dehydrodolichyl diphosphate synthase subunit [Source:Xenbase;Acc:XB-GENE-1002142])

HSP 1 Score: 365.54 bits (937), Expect = 3.056e-114
Identity = 212/680 (31.18%), Postives = 359/680 (52.79%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEIS----NGNDFELNLIKLLKSGLGS----RFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENL-IDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKL-EVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C +E C  +   +   +++  DPC DF  Y CG   +   +  G++ +++F  I       LK +LE  +  + S+ + K   +Y SC+ ++   ++    + ++ ++I     +GN    N + +LK+  G+     FFS+ V+ D+ +   NI+ + +    L       +++++ +++ +Y++YM  V  +LG S    ++ + +IL+    LA       ++ D EK  N+++I ++Q   P+  W+  +   F  + + L + + +V +  EYL    +++     +     +L   L W ++  + S   +   +A ++ +    G K      W+ C+  T  TL   +G++FVKS F  + K   E MI  I+ A +  +  LTWMD  T+ +A EK  AI   IG+PD ++    L + Y   E+S + F  N L F  FS +   + + K  + ++W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + + ++T+C++NQY SY +N + +   QT+GE+IADN G++ +Y A  S L +  E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  K+R+ G +SN  +F++ FNC +   MN  K C VW
Sbjct:   92 LCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYL--TFALSPLDLNDTEPVVVYGKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 764
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Xenopus
Match: dhdds (dehydrodolichyl diphosphate synthase subunit [Source:Xenbase;Acc:XB-GENE-1002142])

HSP 1 Score: 365.155 bits (936), Expect = 3.343e-114
Identity = 212/680 (31.18%), Postives = 359/680 (52.79%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEIS----NGNDFELNLIKLLKSGLGS----RFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENL-IDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKL-EVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C +E C  +   +   +++  DPC DF  Y CG   +   +  G++ +++F  I       LK +LE  +  + S+ + K   +Y SC+ ++   ++    + ++ ++I     +GN    N + +LK+  G+     FFS+ V+ D+ +   NI+ + +    L       +++++ +++ +Y++YM  V  +LG S    ++ + +IL+    LA       ++ D EK  N+++I ++Q   P+  W+  +   F  + + L + + +V +  EYL    +++     +     +L   L W ++  + S   +   +A ++ +    G K      W+ C+  T  TL   +G++FVKS F  + K   E MI  I+ A +  +  LTWMD  T+ +A EK  AI   IG+PD ++    L + Y   E+S + F  N L F  FS +   + + K  + ++W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + + ++T+C++NQY SY +N + +   QT+GE+IADN G++ +Y A  S L +  E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  K+R+ G +SN  +F++ FNC +   MN  K C VW
Sbjct:   83 LCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYL--TFALSPLDLNDTEPVVVYGKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 755
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Xenopus
Match: dhdds (dehydrodolichyl diphosphate synthase subunit [Source:Xenbase;Acc:XB-GENE-1002142])

HSP 1 Score: 359.762 bits (922), Expect = 2.210e-112
Identity = 211/680 (31.03%), Postives = 358/680 (52.65%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEIS----NGNDFELNLIKLLKSGLGSR----FFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENL-IDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKL-EVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C +E C  +   +   +++  DPC DF  Y CG   +   +  G++ +++F  I       LK +LE  +  + S+ + K   +Y SC+ ++   ++    + ++ ++I     +GN    N + +LK+  G+     FFS+ V+ D+ +   NI+ + +    L       +++++ +++ +Y++YM  V  +LG S    ++ + +IL+    LA       ++ D EK  N+++I ++Q   P+  W+  +   F  + + L + + +V +  EYL    +++     +     +L   L W ++  + S   +   +A ++ +    G K      W+ C+  T  TL   +G++FVKS F  + K   E MI  I+ A +  +  LTWMD  T+ +A EK  AI   IG+PD ++    L + Y    +S + F  N L F  FS +   + + K  + ++W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + + ++T+C++NQY SY +N + +   QT+GE+IADN G++ +Y A  S L +  E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  K+R+ G +SN  +F++ FNC +   MN  K C VW
Sbjct:   60 LCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYL--TFALSPLDLNDTEPVVVYGKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVY--DGVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 730
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Xenopus
Match: dhdds (dehydrodolichyl diphosphate synthase subunit [Source:Xenbase;Acc:XB-GENE-1002142])

HSP 1 Score: 357.836 bits (917), Expect = 3.407e-112
Identity = 211/682 (30.94%), Postives = 358/682 (52.49%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEIS----NGNDFELNLIKLLKSGLGSR----FFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENL-IDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYL--TKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKL-EVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C +E C  +   +   +++  DPC DF  Y CG   +   +  G++ +++F  I       LK +LE  +  + S+ + K   +Y SC+ ++   ++    + ++ ++I     +GN    N + +LK+  G+     FFS+ V+ D+ +   NI+ + +    L       +++++ +++ +Y++YM  V  +LG S    ++ + +IL+    LA       ++ D EK  N+++I ++Q   P+  W+  +   F  + + L + + +V +  EYL    +++     +     +L   L W ++  + S   +   +A ++ +    G K      W+ C+  T  TL   +G++FVKS F  + K   E MI  I+ A +  +  LTWMD  T+ +A EK  AI   IG+PD ++    L  T      ++S + F  N L F  FS +   + + K  + ++W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + + ++T+C++NQY SY +N + +   QT+GE+IADN G++ +Y A  S L +  E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  K+R+ G +SN  +F++ FNC +   MN  K C VW
Sbjct:    9 LCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYL--TFALSPLDLNDTEPVVVYGKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDETGLLYTAKVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 683
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Mouse
Match: Ece1 (endothelin converting enzyme 1 [Source:MGI Symbol;Acc:MGI:1101357])

HSP 1 Score: 366.696 bits (940), Expect = 6.516e-115
Identity = 215/708 (30.37%), Postives = 360/708 (50.85%), Query Frame = 3 
Query:  186 IMKTIFVVGLIAILSLCKL-YEGK---VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGN--------DFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISK--TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQ-EEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            ++ T+   GL+A L+   + Y+ +   VC TE C  +   +   M+ + DPC DF SY CG   K   +  G + + +F+ +       +K LLE  +TA+ S+ + KA +YY++CMN+    ++    ++E+ +++   N        +F+  L  +      S FFS+ V+ D+ N   N++ + +    L       +++ +++++  Y+ YM ++  +LG          + +IL     LA        + D E   +K++  ++Q   P+I+W+  +N +F    +++ E + +V +  EYL     ++     +   + +L   + W ++    S       +A+E+FM    G K      WK CV  T + L   +G MFVK+ F    K     +I  IK A +  +  L WMD  T+ SA EK  AI + IGYP+ ++    L K +       + +  N + F  FS       + K  + D+W+M    VNAYY+P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  +T+C++ QY++Y +N +P+    T+GE+IADN G++ +Y A  + ++    + TLP + L+  QLFF+G  + WC++ T     + L  D HS  ++R+ G +SN  EFS+ F C     MN   KC VW
Sbjct:   54 VLVTLLAAGLVACLAALGIQYQTRTPPVCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAVIKHLLEN-ATASVSEAERKAQVYYRACMNETRIEELRAKPLMELIEKLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEDAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIF--YPVEINESEPIVVYDKEYLRQVSTLI-----NNTDKCLLNNYMMWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCIPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIIMEIKKAFEESLSTLKWMDEETRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEQTLPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPHHKCEVW 753
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Mouse
Match: Ece2 (endothelin converting enzyme 2 [Source:MGI Symbol;Acc:MGI:1101356])

HSP 1 Score: 357.836 bits (917), Expect = 9.892e-112
Identity = 208/680 (30.59%), Postives = 350/680 (51.47%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDF----ELNLIKLLKSGLGS----RFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKT-YENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
             C TE C ++  ++ + +++   PC DF  + CG   +   +  G++ +++F  +       LK LLE  +  + S+ + K   +Y SC+  E   K+    + ++  +I   N      E + + +LK+  G+     FF++ V+ D+ +   NI+ + +    L       + +++++++ +Y+ YM ++  +LG   T     + ++L+L I+LA        + D EK  +K+SI ++Q   P++ W+  ++  F  + ++L + + +V +  EYL    +++     +R +  IL   L W ++    S        A E+ +    G K      W+ C+  T   L   +G++FVK+ F    K+  E MI+ I++A +  + +L WMD  T+ +A EK  AI   IG+PD ++    L   Y   E+S ++F  N L    FS +     + K  S D+W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D +G LR WW   S   + + T C+  QY+ Y +N + L  LQT+GE+IADN G++ +Y A  + L    E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  ++R+ G +SN  +F + F C     MN  + C VW
Sbjct:   62 TCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKIGGWNITGPWDEDSFMDVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPAVDWLEFLS--FLLSPLELGDSEPVVVYGTEYLQQVSELI-----NRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 734
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Mouse
Match: Ece2 (endothelin converting enzyme 2 [Source:MGI Symbol;Acc:MGI:1101356])

HSP 1 Score: 357.451 bits (916), Expect = 3.176e-111
Identity = 208/680 (30.59%), Postives = 350/680 (51.47%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDF----ELNLIKLLKSGLGS----RFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKT-YENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
             C TE C ++  ++ + +++   PC DF  + CG   +   +  G++ +++F  +       LK LLE  +  + S+ + K   +Y SC+  E   K+    + ++  +I   N      E + + +LK+  G+     FF++ V+ D+ +   NI+ + +    L       + +++++++ +Y+ YM ++  +LG   T     + ++L+L I+LA        + D EK  +K+SI ++Q   P++ W+  ++  F  + ++L + + +V +  EYL    +++     +R +  IL   L W ++    S        A E+ +    G K      W+ C+  T   L   +G++FVK+ F    K+  E MI+ I++A +  + +L WMD  T+ +A EK  AI   IG+PD ++    L   Y   E+S ++F  N L    FS +     + K  S D+W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D +G LR WW   S   + + T C+  QY+ Y +N + L  LQT+GE+IADN G++ +Y A  + L    E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  ++R+ G +SN  +F + F C     MN  + C VW
Sbjct:   91 TCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKIGGWNITGPWDEDSFMDVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPAVDWLEFLS--FLLSPLELGDSEPVVVYGTEYLQQVSELI-----NRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 763
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Mouse
Match: Gm49333 (predicted gene, 49333 [Source:MGI Symbol;Acc:MGI:6121518])

HSP 1 Score: 357.066 bits (915), Expect = 6.667e-110
Identity = 208/680 (30.59%), Postives = 350/680 (51.47%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDF----ELNLIKLLKSGLGS----RFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKT-YENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
             C TE C ++  ++ + +++   PC DF  + CG   +   +  G++ +++F  +       LK LLE  +  + S+ + K   +Y SC+  E   K+    + ++  +I   N      E + + +LK+  G+     FF++ V+ D+ +   NI+ + +    L       + +++++++ +Y+ YM ++  +LG   T     + ++L+L I+LA        + D EK  +K+SI ++Q   P++ W+  ++  F  + ++L + + +V +  EYL    +++     +R +  IL   L W ++    S        A E+ +    G K      W+ C+  T   L   +G++FVK+ F    K+  E MI+ I++A +  + +L WMD  T+ +A EK  AI   IG+PD ++    L   Y   E+S ++F  N L    FS +     + K  S D+W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D +G LR WW   S   + + T C+  QY+ Y +N + L  LQT+GE+IADN G++ +Y A  + L    E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  ++R+ G +SN  +F + F C     MN  + C VW
Sbjct:  209 TCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKIGGWNITGPWDEDSFMDVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPAVDWLEFLS--FLLSPLELGDSEPVVVYGTEYLQQVSELI-----NRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 881
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Mouse
Match: Gm49333 (predicted gene, 49333 [Source:MGI Symbol;Acc:MGI:6121518])

HSP 1 Score: 356.295 bits (913), Expect = 2.006e-109
Identity = 208/680 (30.59%), Postives = 350/680 (51.47%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDF----ELNLIKLLKSGLGS----RFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKT-YENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
             C TE C ++  ++ + +++   PC DF  + CG   +   +  G++ +++F  +       LK LLE  +  + S+ + K   +Y SC+  E   K+    + ++  +I   N      E + + +LK+  G+     FF++ V+ D+ +   NI+ + +    L       + +++++++ +Y+ YM ++  +LG   T     + ++L+L I+LA        + D EK  +K+SI ++Q   P++ W+  ++  F  + ++L + + +V +  EYL    +++     +R +  IL   L W ++    S        A E+ +    G K      W+ C+  T   L   +G++FVK+ F    K+  E MI+ I++A +  + +L WMD  T+ +A EK  AI   IG+PD ++    L   Y   E+S ++F  N L    FS +     + K  S D+W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D +G LR WW   S   + + T C+  QY+ Y +N + L  LQT+GE+IADN G++ +Y A  + L    E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  ++R+ G +SN  +F + F C     MN  + C VW
Sbjct:  238 TCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKIGGWNITGPWDEDSFMDVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPAVDWLEFLS--FLLSPLELGDSEPVVVYGTEYLQQVSELI-----NRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 910
[Close]
BLAST of Endothelin converting enzyme 1 vs. UniProt/SwissProt
Match: sp|Q8IS64|ECE_LOCMI (Endothelin-converting enzyme homolog OS=Locusta migratoria OX=7004 PE=2 SV=1)

HSP 1 Score: 386.726 bits (992), Expect = 5.305e-122
Identity = 215/688 (31.25%), Postives = 370/688 (53.78%), Query Frame = 3 
Query:  246 EGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMN-KESRNKISHPIILEVAKEISNGN---DFELNLIKLLKS--GLGSRF-----FSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGIS-KTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREK----LTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            E   C +  C      +  +M+ +ADPC DF  Y CG   +   I   ++ + +F ++       +K++LE+  +  +S+ + KA +YY SC++  ++   +    +L++  +I   N   +F +    L KS   L +R+     F+  V +D  + + +I+ I +    L       +E+   +++++Y++YM K+  +LG   K     +  +++    LAK +    D+ D EK  N + +  +Q + P I+W    +   EN   K+ + +K+V ++ EYL+    I++ Y      + IL   L W  + S+ S  S A  +A +      +G +G ++ W+ CV  T++ +   +G MFV+  F  + K   E+MI+ I+ A K+ ++NL WMD+ T+ +A +K  AI   IG+PD +++   L KKY   E+  + +  N L   +++ +  L+ + + ++   W M    VNAYY P  N+IVFPA IL+ PFYDIG P + NYG +GVV+GHE+ H FD QG ++D  G L +WW   + + +  +TQC+++QY++Y ++NK +   QT+GE+IADN G++ +Y A    LE  ++    L LP +  S +QLFF+   + WC+  T   I  QL++D H+  K+R+ GP+SN+ EFS  F C     MN   KC VW
Sbjct:   43 EEAYCVSMSCVTAAASVLSLMDATADPCSDFYQYACGGWVRANPIPDTKSMWGTFVKLEQQNQLVIKNVLEQPMSEFKSEAERKAKLYYMSCLDVNDTIETLGPKPMLDLLVKIGGWNITGNFSIKNWSLQKSLETLQNRYNMGGLFTWAVGEDDRDSKKHIIQIDQGGLTLPTRDNYLNETMDDKVLSAYLEYMTKIGVLLGGEEKNVRTQMKAVIEFETELAKIMSPQEDRRDEEKLYNNMELDKVQGRPPFINWHAFFSNAMENITRKISKKEKVVVYAPEYLEKLNDIIRNYTNTTDGKIILNNYLVWQTVRSMTSYLSKAFRDAYKGLRKALVGSEGGEKPWRYCVTDTNNVIGFAIGAMFVREAFHGNSKPAAENMINQIRTAFKSNLKNLKWMDAETRRAAEKKADAISDMIGFPDYILNPEELDKKYKDLEIKEDEYFENNLRVNKYNLKSNLEKLDQPVNKTRWGMTPPTVNAYYTPTKNQIVFPAGILQAPFYDIGHPKSMNYGAMGVVMGHELTHAFDDQGREYDQNGNLHKWWNNQTIEAFKKRTQCVVDQYSNYTVDNKHVNGKQTLGENIADNGGLKAAYHAY---LEWEQRNPRELPLPGLNFSHKQLFFLSFAQVWCSASTDEAIKLQLEKDPHAPPKFRVIGPLSNLQEFSTEFRCPLGSKMNPVHKCEVW 727
[Close]
BLAST of Endothelin converting enzyme 1 vs. UniProt/SwissProt
Match: sp|Q4PZA2|ECE1_MOUSE (Endothelin-converting enzyme 1 OS=Mus musculus OX=10090 GN=Ece1 PE=1 SV=1)

HSP 1 Score: 366.696 bits (940), Expect = 6.400e-114
Identity = 215/708 (30.37%), Postives = 360/708 (50.85%), Query Frame = 3 
Query:  186 IMKTIFVVGLIAILSLCKL-YEGK---VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGN--------DFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISK--TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQ-EEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            ++ T+   GL+A L+   + Y+ +   VC TE C  +   +   M+ + DPC DF SY CG   K   +  G + + +F+ +       +K LLE  +TA+ S+ + KA +YY++CMN+    ++    ++E+ +++   N        +F+  L  +      S FFS+ V+ D+ N   N++ + +    L       +++ +++++  Y+ YM ++  +LG          + +IL     LA        + D E   +K++  ++Q   P+I+W+  +N +F    +++ E + +V +  EYL     ++     +   + +L   + W ++    S       +A+E+FM    G K      WK CV  T + L   +G MFVK+ F    K     +I  IK A +  +  L WMD  T+ SA EK  AI + IGYP+ ++    L K +       + +  N + F  FS       + K  + D+W+M    VNAYY+P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  +T+C++ QY++Y +N +P+    T+GE+IADN G++ +Y A  + ++    + TLP + L+  QLFF+G  + WC++ T     + L  D HS  ++R+ G +SN  EFS+ F C     MN   KC VW
Sbjct:   70 VLVTLLAAGLVACLAALGIQYQTRTPPVCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAVIKHLLEN-ATASVSEAERKAQVYYRACMNETRIEELRAKPLMELIEKLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEDAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIF--YPVEINESEPIVVYDKEYLRQVSTLI-----NNTDKCLLNNYMMWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCIPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIIMEIKKAFEESLSTLKWMDEETRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEQTLPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPHHKCEVW 769
[Close]
BLAST of Endothelin converting enzyme 1 vs. UniProt/SwissProt
Match: sp|P97739|ECE1_CAVPO (Endothelin-converting enzyme 1 OS=Cavia porcellus OX=10141 GN=ECE1 PE=2 SV=1)

HSP 1 Score: 365.155 bits (936), Expect = 1.587e-113
Identity = 218/710 (30.70%), Postives = 364/710 (51.27%), Query Frame = 3 
Query:  186 IMKTIFVVGLIAILSLCKL-YEGK---VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGN--------DFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLI----DEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            ++  +   GL+A L+   + Y  +   VC +E C  +   +   MN + DPC DF SY CG   K   +  G + + +F+ +       +K LLE  STA+ S+ + KA +YY++CMN+    ++    ++E+ +++   N        +F+  L  +      S FFS+ V+ D+ N   N++++ +    L       +++ +++++  Y+ YM ++  +LG     EN I     +IL     LA        + D E   +K++  ++Q   P+I+W+  +N +F    +++ E + +V +  EYL+    ++     +   + +L   + W ++    S       +A+E+FM    G K      WK CV  T + L   +G MFVK+ F    K     +I  IK A +  +  L WMD +T+ SA EK  AI + IGYP+ ++    L K +       + +  N + F  FS     + + K  + D+W+M    VNAYY+P  NEIVFPA IL  PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  +T+C++ QY++Y +N +P+    T+GE+IADN G++ +Y A  + ++    + TLP + L+  QLFF+G  + WC++ T     + L  D HS  ++R+ G +SN  EFS+ F C     MN + KC VW
Sbjct:   55 VLVALLAAGLVACLTALGIQYRTRTPPVCLSEACVSVTSSILNSMNPTVDPCQDFFSYACGGWIKANPVPDGHSRWGAFSNLWEHNQAIIKHLLE-NSTASVSEAERKAQVYYRACMNETRIEELRAKPLMELIEKLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNRNVIHVDQSGLGLPSRDYYLNKTENEKVLNGYLNYMVQLGKLLGGGD--ENAIRAQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIF--YPVEINESEPIVVYDKEYLEQVSTLI-----NTTDKCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFGLGPMFVKATFAEDSKNIASEIILEIKKAFEESLSTLKWMDEDTRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTAEQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILPAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEETLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFQCPPGSPMNPRHKCEVW 754
[Close]
BLAST of Endothelin converting enzyme 1 vs. UniProt/SwissProt
Match: sp|P42893|ECE1_RAT (Endothelin-converting enzyme 1 OS=Rattus norvegicus OX=10116 GN=Ece1 PE=1 SV=2)

HSP 1 Score: 364.77 bits (935), Expect = 3.322e-113
Identity = 215/708 (30.37%), Postives = 360/708 (50.85%), Query Frame = 3 
Query:  186 IMKTIFVVGLIAILSLCKL-YEGK---VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGN--------DFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISK--TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            ++ T+   GL+A L+   + Y  +   VC TE C  +   +   M+ + DPC DF SY CG   K   +  G + + +F+ +       +K LLE  STA+ S+ + KA +YY++CMN+    ++    ++E+ +++   N        +F+  L  +      S FFS+ V+ D+ N   N++ + +    L       +++ +++++  Y+ YM ++  +LG     +    + +IL     LA        + D E   +K++  ++Q   P+I+W+  +N +F    +++ E + +V +  EYL     ++     +   + +L   + W ++    S       +A+E+FM    G K      WK CV  T + L   +G MFVK+ F    K     +I  IK A +  +  L WMD +T+ SA EK  AI + IGYP+ ++    L K +       + +  N + F  FS       + K  + D+W+M    VNAYY+P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  +T+C++ QY +Y +N +P+    T+GE+IADN G++ +Y A  + ++    +  LP + L+  QLFF+G  + WC++ T     + L  D HS  ++R+ G +SN  EFS+ F C     MN + KC VW
Sbjct:   63 VLVTLLAAGLVACLAALGIQYRTRTPPVCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLEN-STASASEAEKKAQVYYRACMNETRIEELRAKPLMELIEKLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEDSIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNAIF--YPVEINESEPIVVYDKEYLRQVSTLI-----NSTDKCLLNNYMMWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIILEIKKAFEESLSTLKWMDEDTRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSLRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYNNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEQILPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPLGSPMNPRHKCEVW 762
[Close]
BLAST of Endothelin converting enzyme 1 vs. UniProt/SwissProt
Match: sp|F1N476|ECE2_BOVIN (Endothelin-converting enzyme 2 OS=Bos taurus OX=9913 GN=ECE2 PE=2 SV=1)

HSP 1 Score: 359.377 bits (921), Expect = 3.444e-111
Identity = 207/680 (30.44%), Postives = 352/680 (51.76%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDF----ELNLIKLLKSGLGS----RFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKT-YENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
             C TE C ++  ++ + +++   PC+DF  + CG   +   +  G++ +++F  +       LK LLE  +  + S+ + K   +Y SC+  E   ++    + ++  +I   N      + N +++LK+  G+     FF++ V+ D+ +   NI+ + +    L       + +++++++ +Y+ YM+++  +LG   T     + ++L+L I+LA        + D EK  +K+SI ++Q   PS+ W+  ++  F  + ++L + + +V +  +YL    +++     +R +  +L   L W ++    S   +    A E+ +    G K      W+ C+  T   L   +G++FVK+ F    K+  E MI  I+AA +  + +L WMD  T+ +A EK  AI   IG+PD ++    L   Y   E+S ++F  N L    FS +     + K  S D+W+M  Q VNAYY P  NEIVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D +G LR WW   S   + + T CI  QY+ Y +N + L   QT+GE+IADN G++ +Y A  + L    E+  LP V L+  QLFFVG  + WC++ T     + L  D HS  ++R+ G +SN  +F + F C     MN  + C VW
Sbjct:   93 TCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNVTGPWDQDNFMEVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGQPTSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQALAPSMDWLEFLS--FLLSPLELGDSEPVVVYGTDYLQQVSELI-----NRTEPSVLNNYLIWNLVQKTTSSLDHRFESAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEEALGHLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYTCNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACIEEQYSQYQVNGEKLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNSGQLCEVW 765
[Close]
BLAST of Endothelin converting enzyme 1 vs. TrEMBL
Match: A0A2T7PT70 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_03607 PE=4 SV=1)

HSP 1 Score: 403.29 bits (1035), Expect = 2.745e-125
Identity = 230/736 (31.25%), Postives = 394/736 (53.53%), Query Frame = 3 
Query:  141 KKTFLNIHLKLNNFKIMKTIFVVGLIAILSLCKL-------------YEGK-VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCM--NKESRNKISHPIILEVAKEISNGNDFE--------LNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKE-IIASYIKYMKKVLNILGISKTYENLID---EILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            K  +L+ H +    K++  + V+  +A++ L  L             ++GK VC T  C  +   L   M++S +PCDDF  Y CG   K + I  G   + +F  +       +K+ +E+  ++  S+ + KA +YY SCM  NK      + P++  + +   N + F+         ++++ ++    S FFS+ + +D  N   NI+ I +    L E     +++  ++ ++++Y+ YM  + N+L   + + NL +   E++K   +LA+   S  D+ D EK  + +++ D+ + +P I W+  IN +     I +   +++V ++ EYL+   +IL   L   + R  +   LEW V+ S+VS  S     A +EF     G  GK++EW+ C+  T S L   +G +FVK+ F    K+  E MI+ IK A KN + +L WMDS+T+ +A++K  A+   IG+P  +++ + L ++Y+   ++ + +  N +  L F  ++ ++ + +    + W M    VNAYY P  NEIVFPA IL+ PFYD   P + N+G +GVV+GHE+ HGFD QG +FD  G LR WW  +S   +  +TQC+ +QY+ Y +  + +   QT+GE+IADN G++ ++ A    L    E+  LP V L+  Q+FF+G  + WC+  TK     Q+ +D HS  K+R+ G +SN  +F++ +NC    +MN  KKC VW
Sbjct:   45 KGGWLSWHRRNTQEKVLIVVLVLMTVALIVLASLLAVKDAAIRRLDQHKGKDVCLTPECVTIASSLLTTMDRSINPCDDFYEYACGGWIKTHPIPSGHARWGTFGTMWQENQLIMKNAIEEPVSSFASEAEQKAKLYYTSCMDPNKTVEKLGAQPLLDLMTQFKVNLSHFDSPDDGWIFQDMLEKVQLYDISAFFSLWIGEDDKNSSRNIIQIDQDGLGLPERDYYINKTIEEDKVLSAYLNYMVTINNLLAPGR-HPNLTEHLTEVIKFESKLAEITTSAEDRRDEEKIYHNMTVADLNQLYPMIDWLHFINRLLATANITIDSSEEVVIYAPEYLEKLSQILNSTLSTLEGRRAVNLYLEWHVVKSMVSYLSKPFRNAKKEFSEVLSGASGKEDEWRYCISDTDSVLGFALGALFVKNAFHGDSKEKAEEMIEEIKDAFKNNLPHLEWMDSSTRQAAIDKANAVVDMIGFPKYILNASRLDEEYSELLINESEYFLNNVRNLHFVLKKNMEKLNQAPKQNVWGMTPPTVNAYYTPAKNEIVFPAGILQAPFYDKNFPKSLNFGAMGVVMGHELTHGFDDQGREFDKNGNLRPWWNDASVKRFQERTQCMADQYSQYTLGGENIRGKQTLGENIADNGGLKCAFHAYEDWLSKNGEEQMLPAVNLTHRQIFFLGFAQVWCSSSTKEANHLQIVKDPHSPAKFRVIGTLSNSKDFAEHWNCAAGSSMNPVKKCEVW 779
[Close]
BLAST of Endothelin converting enzyme 1 vs. TrEMBL
Match: T1I0G9 (Uncharacterized protein (Fragment) OS=Rhodnius prolixus OX=13249 PE=4 SV=1)

HSP 1 Score: 389.808 bits (1000), Expect = 1.408e-120
Identity = 208/686 (30.32%), Postives = 375/686 (54.66%), Query Frame = 3 
Query:  246 EGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMN-KESRNKISHPIILEVAKEI---SNGNDFEL------NLIKLLKS--GLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTY-ENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFA-ANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            E   C TE+C      L   +++S DPCDDF  + CGN  K   I  G++ + +F ++       +K+ LEK     +S+ + KA  YY SCM+  E+   +    +L + KE+   S  ++F++      N +++L++   +G   FS  V +D  N   +I+ + +    L       + +++++I+ +Y++YM ++  +LG  +   ++L+ E+++   RLA+      ++ D EK  N +++ ++Q   P I+W +  ++       K+ + +K+V ++  YL +   +L  Y+   +    +   L W  + S+ +  S    +A +      +G +G +E W+ CV  T++ L   +G M+V+  FQ   K   + MI+ ++ A K  ++ L WMD  T+  A  K  AI   IG+PD ++    L +KY   E+S  ++  N +   +++ ++ L+ +G+ ++   W M    VNAYY P  N+I FPA IL+ PFYD+      N+G +GVV+GHE+ H FD QG ++D  G + +WW   + D +  + +C++NQY+SY +NNK +   QT+GE+IADN G++ +Y A  +   + +E+L LP V L+ +QLFF+   + WC+  T+   + Q+++D H+  K+R+ G +SN P+F++ FNC     MN +KKC+VW
Sbjct:   57 EESYCLTEVCVTTAASLVSSIDRSVDPCDDFYQFACGNWIKANPIPDGKSMWGTFVKLDQQNQLVMKNALEKPMQEIKSKAEKKAKFYYMSCMDSNETIETLGATPMLNLLKEVGGWSIDDNFDIEKWSLQNTLQILQNRYNMGG-LFSWAVQEDDRNSSLHIIQVDQGGLTLPTRDTYLNATANEKILHAYLEYMTEIGVLLGGERNRTKSLMKEVIEFETRLAQITIPADERRDEEKMYNLMAVAELQDLAPFINWEKYFSDALRLVRKKITDKEKVVVYAPNYLANLTIVLNEYMNTSEGNITINNYLVWQTVRSMTACLSRPFRDAYKGLKKALIGTEGGEESWRYCVTDTNNVLGFALGAMYVREVFQGKSKSKAQEMINAVRTAFKENLKELKWMDKETRELAEAKADAITDMIGFPDYILDPKQLDEKYKDLEVSEGHYFQNNINANQYNLKQNLRKLGQPVNRTRWNMTPSTVNAYYTPNRNQIAFPAGILQAPFYDVRHLQALNFGAMGVVMGHELTHAFDDQGREYDKYGNMHQWWNNKTIDRFKEQAECVVNQYSSYQMNNKRINGKQTLGENIADNGGLKAAYRAFTDWAAKNKEELPLPAVNLTHKQLFFLSFAQVWCSASTEEATNLQVEKDTHATPKFRVIGSLSNSPDFAENFNCREGSKMNPKKKCVVW 741
[Close]
BLAST of Endothelin converting enzyme 1 vs. TrEMBL
Match: A0A4S2K871 (F-box domain-containing protein OS=Temnothorax longispinosus OX=300112 GN=DBV15_09151 PE=4 SV=1)

HSP 1 Score: 402.519 bits (1033), Expect = 1.776e-120
Identity = 223/686 (32.51%), Postives = 363/686 (52.92%), Query Frame = 3 
Query:  246 EGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMN-KESRNKISHPIILEVAKEISNGN---DFELNLIKLLKS--------GLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISK-TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLE-VREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +G  C TE C  +   L   ++ S DPCDDF  Y CG   K   I  G+N + +F ++       +K++LEK  +  +S+ + KA  YY SCM+  E+   +    +LE+ + I   N    F ++   L  S         +G   FS  V++D  N    I+ I +    L       + S   +++ +Y+ YM K+  +LG  + T +  + +++    RLA+      ++ D EK  N +S+ D+QKK P +SW+            K+     +V F+ EY  +  K+++ Y      + IL   L W  + SL +  S    EA +      LG++G +E+W+ CV   ++ +   +G MFV+  FQ   K   E MI++I+ A     +NL WMD+ T+++A EK  AI   IG+PD ++  + L ++Y    +  N +  N L   ++S  + L+ + + ++   W M    VNAYY P  N++VFPA IL+ PFYD+  P + N+GG+GVV+GHE+ H FD QG ++D  G L  WW  ++ + + ++T+C + QY  Y +  + +   QT+GE+IADN G+R +Y A  S  +  +++L LP + L+  QLFF+   + WC+ +T   +  Q+++D HS  KYR+ GP+SNMPEFS  FNC ++  MN   KC VW
Sbjct:  578 DGTHCLTEQCVTVAASLINSIDNSVDPCDDFYEYACGGWKKKNPIPDGRNVWGTFGKLEQDNQLVVKNVLEKPLSEMKSKAEKKAKYYYLSCMDANETIETLGAKPMLELLENIGGWNISGKFNISAWSLQNSMHVLQNVYNMGG-LFSWGVSEDDRNSTRYIIQIDQGGLTLPTADNYLNVSEHGKVLTAYLDYMTKIGVLLGGEENTTKKQMQDVIAFETRLAEITIPPEERRDEEKMYNLMSLNDLQKKAPFMSWVEFFQNATRLVNKKINSKAMIVNFAPEYFGNLTKVVQEYNRTTSGKIILNNYLVWQTVRSLTAFLSKPFREAYKGLRKALLGMEGHEEQWRYCVNDVNNAMGFAIGAMFVREVFQGKSKPMAEEMINHIRKAFTKNFKNLNWMDAETRNAAEEKANAITDMIGFPDFILQASELDERYRDLSIKQNEYFQNTLRVNKYSFRKNLEKLDQVVNKTTWIMTPPAVNAYYTPTKNQMVFPAGILQSPFYDMKNPYSLNFGGVGVVMGHELTHAFDDQGREYDLHGNLHHWWNDATVERFKNRTECFVEQYNQYQVQGRNINGRQTLGENIADNGGLRAAYHAYLSMTKSYKDQLPLPGLNLTHRQLFFLNFAQIWCSSITSETVTLQIEKDTHSPPKYRVIGPLSNMPEFSTEFNCPKDSKMNPVHKCEVW 1262
[Close]
BLAST of Endothelin converting enzyme 1 vs. TrEMBL
Match: A0A026WJ96 (Endothelin-converting enzyme OS=Ooceraea biroi OX=2015173 GN=X777_05239 PE=4 SV=1)

HSP 1 Score: 390.193 bits (1001), Expect = 2.670e-120
Identity = 215/686 (31.34%), Postives = 366/686 (53.35%), Query Frame = 3 
Query:  246 EGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMN-KESRNKISHPIILEVAKEISNGN---DFELNLIKLLKS--------GLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISK-TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLE-VREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +G  C TE C  +   +   ++ SADPC DF  Y CG   K   I  G++ + +F ++       +K++LEK  +  +S+ + KA  YYQSCM+  E+  ++    +LE+ + I   N    F++N   L  S         +G   FS  V +D  N   +I+ I +    L       + +   +++A+Y+ YM K+  +LG  + + +  + +++    +LA+      ++ D EK  N +S+ D+Q++ P +SW+            K+     +V F+ EY     K+++ Y      + IL   L W  + SL +  S    +A +      LG +G +E+W+ CV   ++ +   +G MFV+  F    K   E MID ++ A    ++NL WMD+ T+ +A EK  AI   IG+PD ++  + L ++Y    +    +  N L   +++ ++ L+   ++++   W M    VNAYY P  N+IVFPA IL+ PFYD+  P + N+GGIGVV+GHE+ H FD QG ++D  G L +WW  ++ + + ++T+C + QY+ Y +  + +   QT+GE+IADN G++ +Y A  S  +  +++L LP + L+  QLFF+   + WC+ +T   +  Q+++D HS  KYR+NGP+SN+PEF+  FNC ++  MN   KC VW
Sbjct:   91 DGTHCLTEHCVTVAASIINSIDYSADPCGDFYEYACGGWRKKNPIPDGKSVWGTFGKLEQDNQLVVKNVLEKPFSEMKSKAEKKAKYYYQSCMDANETIEELGAKPMLELLEIIGGWNVSGKFDVNTWSLQNSMHILQNVYNMGG-LFSWAVNEDDRNSSRHIIQIDQGGLTLPTADNYLNVTEHGKVLAAYLDYMTKIGVLLGGEENSTKRQMQDVIDFETKLAEITTPPDERRDEEKLYNLMSLSDLQRRAPFMSWVDYFQNATRLVNKKVNSKVMIVNFAPEYFVKLTKLVQQYNKTTNGKIILNNYLVWQTVRSLTACLSKPFRDAYKGLRKALLGSEGHEEQWRYCVSDVNNAMGFAIGAMFVREVFHGKSKPMAEEMIDQVRKAFTKNLKNLDWMDAETRKAAEEKANAITDMIGFPDFILQPSALDERYRDLVIKQYEYFQNNLRVNKYNLKKNLEKFEQEVNKTTWIMTPPTVNAYYTPTKNQIVFPAGILQSPFYDMENPNSLNFGGIGVVMGHELTHAFDDQGREYDLHGNLHQWWNDATIERFKNRTECFVEQYSQYQVQGRHVNGRQTLGENIADNGGLKAAYHAYLSMPKSYKDQLPLPGLNLTHRQLFFLNFAQVWCSAITSEAVTLQIEKDSHSPPKYRVNGPLSNLPEFAMEFNCPKDSKMNPGHKCEVW 775
[Close]
BLAST of Endothelin converting enzyme 1 vs. TrEMBL
Match: A0A3L8E1J0 (Uncharacterized protein OS=Ooceraea biroi OX=2015173 GN=DMN91_000048 PE=4 SV=1)

HSP 1 Score: 390.193 bits (1001), Expect = 3.328e-120
Identity = 215/686 (31.34%), Postives = 366/686 (53.35%), Query Frame = 3 
Query:  246 EGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMN-KESRNKISHPIILEVAKEISNGN---DFELNLIKLLKS--------GLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISK-TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLE-VREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +G  C TE C  +   +   ++ SADPC DF  Y CG   K   I  G++ + +F ++       +K++LEK  +  +S+ + KA  YYQSCM+  E+  ++    +LE+ + I   N    F++N   L  S         +G   FS  V +D  N   +I+ I +    L       + +   +++A+Y+ YM K+  +LG  + + +  + +++    +LA+      ++ D EK  N +S+ D+Q++ P +SW+            K+     +V F+ EY     K+++ Y      + IL   L W  + SL +  S    +A +      LG +G +E+W+ CV   ++ +   +G MFV+  F    K   E MID ++ A    ++NL WMD+ T+ +A EK  AI   IG+PD ++  + L ++Y    +    +  N L   +++ ++ L+   ++++   W M    VNAYY P  N+IVFPA IL+ PFYD+  P + N+GGIGVV+GHE+ H FD QG ++D  G L +WW  ++ + + ++T+C + QY+ Y +  + +   QT+GE+IADN G++ +Y A  S  +  +++L LP + L+  QLFF+   + WC+ +T   +  Q+++D HS  KYR+NGP+SN+PEF+  FNC ++  MN   KC VW
Sbjct:   95 DGTHCLTEHCVTVAASIINSIDYSADPCGDFYEYACGGWRKKNPIPDGKSVWGTFGKLEQDNQLVVKNVLEKPFSEMKSKAEKKAKYYYQSCMDANETIEELGAKPMLELLEIIGGWNVSGKFDVNTWSLQNSMHILQNVYNMGG-LFSWAVNEDDRNSSRHIIQIDQGGLTLPTADNYLNVTEHGKVLAAYLDYMTKIGVLLGGEENSTKRQMQDVIDFETKLAEITTPPDERRDEEKLYNLMSLSDLQRRAPFMSWVDYFQNATRLVNKKVNSKVMIVNFAPEYFVKLTKLVQQYNKTTNGKIILNNYLVWQTVRSLTACLSKPFRDAYKGLRKALLGSEGHEEQWRYCVSDVNNAMGFAIGAMFVREVFHGKSKPMAEEMIDQVRKAFTKNLKNLDWMDAETRKAAEEKANAITDMIGFPDFILQPSALDERYRDLVIKQYEYFQNNLRVNKYNLKKNLEKFEQEVNKTTWIMTPPTVNAYYTPTKNQIVFPAGILQSPFYDMENPNSLNFGGIGVVMGHELTHAFDDQGREYDLHGNLHQWWNDATIERFKNRTECFVEQYSQYQVQGRHVNGRQTLGENIADNGGLKAAYHAYLSMPKSYKDQLPLPGLNLTHRQLFFLNFAQVWCSAITSEAVTLQIEKDSHSPPKYRVNGPLSNLPEFAMEFNCPKDSKMNPGHKCEVW 779
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Cavefish
Match: ece2b (endothelin-converting enzyme 2 [Source:NCBI gene;Acc:103045399])

HSP 1 Score: 380.948 bits (977), Expect = 2.657e-120
Identity = 214/682 (31.38%), Postives = 359/682 (52.64%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFEL----NLIKLLKSGLG----SRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDS--ESSSKEIIASYIKYMKKVLNILGISK-TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C TE C  +  ++ + ++++ DPC DF  Y CG   +   +  G++ + +F  I       LK LLE  +  + S+ + KA  YY SC+N++   ++    ++++  +    N  E     N + +LK+  G      FF++ V+ D  N   N++ + +    L     RD     ++++++ +Y+ YM ++  +LG  K + +N + +IL     LA       ++ D EK  +K++I ++Q   P++ W+  ++ V   + ++L + + +V ++ EYL    +++     ++  R +L   + W ++    S        A ++ +    G K      W+ C+  T  TL   +G +FV + F    K+  E MI+ I+ A ++ +++L WMD  T+ +A EK   I   IGYPD ++    L   Y   ++S +NF  N L F  FS       + K  + D+W+M    VNAYY P  N IVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS D + ++T+C+++QY  Y IN + +   QT+GE+IADN G++ +Y A  S ++   E+ +LP V L+ +QLFFVG  + WC++ T     + L  D HS  KYR+ G +SN P+FS+ FNC     MN   +C VW
Sbjct:   94 LCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKTGGWNITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLPS---RDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQTLAPAVEWLDYLSSVL--SPLELNDTEPVVVYAKEYLQQVSELI-----NKTDRNLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVNATFDKHSKEIAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 765
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Cavefish
Match: ece2b (endothelin-converting enzyme 2 [Source:NCBI gene;Acc:103045399])

HSP 1 Score: 380.563 bits (976), Expect = 3.356e-120
Identity = 214/682 (31.38%), Postives = 359/682 (52.64%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFEL----NLIKLLKSGLG----SRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDS--ESSSKEIIASYIKYMKKVLNILGISK-TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C TE C  +  ++ + ++++ DPC DF  Y CG   +   +  G++ + +F  I       LK LLE  +  + S+ + KA  YY SC+N++   ++    ++++  +    N  E     N + +LK+  G      FF++ V+ D  N   N++ + +    L     RD     ++++++ +Y+ YM ++  +LG  K + +N + +IL     LA       ++ D EK  +K++I ++Q   P++ W+  ++ V   + ++L + + +V ++ EYL    +++     ++  R +L   + W ++    S        A ++ +    G K      W+ C+  T  TL   +G +FV + F    K+  E MI+ I+ A ++ +++L WMD  T+ +A EK   I   IGYPD ++    L   Y   ++S +NF  N L F  FS       + K  + D+W+M    VNAYY P  N IVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS D + ++T+C+++QY  Y IN + +   QT+GE+IADN G++ +Y A  S ++   E+ +LP V L+ +QLFFVG  + WC++ T     + L  D HS  KYR+ G +SN P+FS+ FNC     MN   +C VW
Sbjct:   92 LCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKTGGWNITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLPS---RDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQTLAPAVEWLDYLSSVL--SPLELNDTEPVVVYAKEYLQQVSELI-----NKTDRNLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVNATFDKHSKEIAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 763
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Cavefish
Match: ece2b (endothelin-converting enzyme 2 [Source:NCBI gene;Acc:103045399])

HSP 1 Score: 380.563 bits (976), Expect = 5.973e-120
Identity = 214/682 (31.38%), Postives = 359/682 (52.64%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFEL----NLIKLLKSGLG----SRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDS--ESSSKEIIASYIKYMKKVLNILGISK-TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C TE C  +  ++ + ++++ DPC DF  Y CG   +   +  G++ + +F  I       LK LLE  +  + S+ + KA  YY SC+N++   ++    ++++  +    N  E     N + +LK+  G      FF++ V+ D  N   N++ + +    L     RD     ++++++ +Y+ YM ++  +LG  K + +N + +IL     LA       ++ D EK  +K++I ++Q   P++ W+  ++ V   + ++L + + +V ++ EYL    +++     ++  R +L   + W ++    S        A ++ +    G K      W+ C+  T  TL   +G +FV + F    K+  E MI+ I+ A ++ +++L WMD  T+ +A EK   I   IGYPD ++    L   Y   ++S +NF  N L F  FS       + K  + D+W+M    VNAYY P  N IVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS D + ++T+C+++QY  Y IN + +   QT+GE+IADN G++ +Y A  S ++   E+ +LP V L+ +QLFFVG  + WC++ T     + L  D HS  KYR+ G +SN P+FS+ FNC     MN   +C VW
Sbjct:  115 LCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKTGGWNITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLPS---RDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQTLAPAVEWLDYLSSVL--SPLELNDTEPVVVYAKEYLQQVSELI-----NKTDRNLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVNATFDKHSKEIAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 786
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Cavefish
Match: ece2b (endothelin-converting enzyme 2 [Source:NCBI gene;Acc:103045399])

HSP 1 Score: 349.747 bits (896), Expect = 8.191e-109
Identity = 208/681 (30.54%), Postives = 349/681 (51.25%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFEL----NLIKLLKSGLG----SRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDS--ESSSKEIIASYIKYMKKVLNILGISK-TYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C TE C  +  ++ + ++++ DPC DF  Y CG   +   +  G++ + +F  I       LK LLE  +  + S+ + KA  YY SC+N++   ++    ++++  +    N  E     N + +LK+  G      FF++ V+ D  N   N++ + +    L     RD     ++++++ +Y+ YM ++  +LG  K + +N + +IL     LA       ++ D EK  +K++I ++Q   P++ W+  ++ V   + ++L + + +V ++ EYL    +++     ++  R +L   + W    +LV  G+++L +  E                          L+ + G             K  E MI+ I+ A ++ +++L WMD  T+ +A EK   I   IGYPD ++    L   Y   ++S +NF  N L F  FS       + K  + D+W+M    VNAYY P  N IVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS D + ++T+C+++QY  Y IN + +   QT+GE+IADN G++ +Y A  S ++   E+ +LP V L+ +QLFFVG  + WC++ T     + L  D HS  KYR+ G +SN P+FS+ FNC     MN   +C VW
Sbjct:   94 LCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKTGGWNITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLPS---RDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQTLAPAVEWLDYLSSVL--SPLELNDTEPVVVYAKEYLQQVSELI-----NKTDRNLLNNYMIW----NLVQKGASSLDQRFE--------------------NAQDKLLESLYGT------------KKAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 728
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Cavefish
Match: mmel1 (membrane metalloendopeptidase like 1 [Source:NCBI gene;Acc:103025396])

HSP 1 Score: 323.168 bits (827), Expect = 1.759e-98
Identity = 204/704 (28.98%), Postives = 346/704 (49.15%), Query Frame = 3 
Query:  246 EGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDS-FTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNK---ESRNKISHPII--------LEVAKEISNGNDFELNLIKLLKSGLGSRF-----FSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNIL----GISKTYENLIDEI---LKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKF--PSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETY--LTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASY---VINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +  VC T  C      L + M+ S DPC +F  Y CG   + + ++P  +S  S F  +   +   LK +LE +S  +R Q   KA + Y+SCMN+   E R+  S P++          VA E  N    E   +    + L + +       + V  D  +   +I++I +P+  +       ++ + K++  +Y+++M  +  I      +++  E++ DE+   ++L   +A A     +++D     NK+++R++Q  F     +W R I  + E+  I +  ++ +V +   YLD    IL  Y      R  +Q  L W ++   VS  S    +    +     G   ++  W+ CV+   S ++  VG ++V+  F    K+ +  +I  I+ A    +E L WMD  +K  A EK  AI  +IGYPD ++ E    L ++Y     S  ++  N L  L+ + ++  K + + + PD W +G+  VNA+Y+   N+IVFPA IL+ PF+        N+GGIG+VIGHEI HGFD  G  FD  G +  WW+  S + +  +++C++ QY  +   +   + +  + T+GE+IADN G+R +Y A    +E   E+  LP + L  +QLFF+   + WC      Y    +K D HS  +YR+ G + N   FS+ F+C R   MN ++KC VW
Sbjct:   71 DSSVCTTPDCVTAAARLLQNMDPSVDPCQNFYQYACGGWLERH-VIPETSSLHSVFNILRDELEIVLKGILETESERDR-QAFKKAKMLYRSCMNESVIEQRD--SQPLLKLIDSIGDWPVASEDWNSTAEETWRLDETLATLNAHYNKKVLLEMFVWPDDRDSSRHIIHIDQPSLGMPSRDYYLNDGNYKKVREAYLQFMVSMAKIAREDRNLTQDDEHVWDEVKQVMELEREIANATSPAEERNDITVLYNKMTLRELQDTFGLDGFNWTRYIQGIMESVSIVVNPEEPIVVYCSPYLDKLNNILPRY-----DRRTVQNYLVWMLLMERVSSLSRRFKDVRAHYRKALHGTTVEEARWRDCVRYVQSNMENAVGALYVRETFAGESKRMVGELIRKIQEAFVETVEELNWMDDQSKEKAREKAMAISEQIGYPDYILQEETQKLDQEYTHLNFSEESYFENILQNLQATAQKGHKKLREPVDPDLWIIGAAVVNAFYSHNRNQIVFPAGILQPPFFSEKQLQALNFGGIGMVIGHEITHGFDDHGRNFDKDGNMYNWWSNYSTEHFEEQSKCMVQQYGKFTWKLAGGQNVSGITTLGENIADNGGVRQAYKAYMKWIEREGEESYLPGLDLDHKQLFFLNFAQVWCGACRPEYAIQSIKTDPHSPLEYRVLGSLQNFEAFSEAFHCQRGAPMNPEEKCRVW 765
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Sea Lamprey
Match: mmel1 (membrane metallo-endopeptidase-like 1 [Source:ZFIN;Acc:ZDB-GENE-101112-2])

HSP 1 Score: 307.375 bits (786), Expect = 8.356e-94
Identity = 199/678 (29.35%), Postives = 336/678 (49.56%), Query Frame = 3 
Query:  306 MNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEIS-------NGN---DFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSK-EIIASYIKYMKKVLNILGISKTYEN-------LIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFP--SISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLI--SETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASY---VINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            M+ SADPC DF  Y CG   K   I    + +  F  +   +   LK +LEK   A R   + K+   Y SC+++E    ++   +L++   ++       N N   +++ NL  L K        +  V  D  N    I+NI +P F L       SE+ S  +   +Y  ++  + NI+   K   +        ++ +     +LA+A     +++D     +K+S+ ++   +   + SW+  + ++F +    +   + +V ++ EYL   IK LK  L D     I Q  + W +    V   S    +A  EF     G    +  W+ C    ++ L   VG ++V+  F    KK ++ ++ +I+    + ++ +TWMD  TK  A +K  AI  +IGYP+ ++  ++  + ++YA    S   +  N L  L F ++  L  +   +  +EW  G+  VNA+Y+   N+IVFPA IL+ PF+ +   ++ N+GGIG+VIGHEI+HGFD  G  FD  G L +WW+  S   +  K+QCII+QY ++   +   + L  + T+GE+IADN G+R +Y A  + ++   E+L LP + LS +QLFF+   + WC      Y  + +K DVHS  K+R+ G + N  +FS+ + C  +  MN + KC VW
Sbjct:   37 MDPSADPCKDFYKYACGGWLKKNIIPETSSRYGVFDILRDELEVVLKAVLEKSDDAARDAYK-KSRTLYASCIDQEKIEALNSQPLLQLLGNVNEWPIATVNWNTTQEYQKNLANLAKKYRVRPIVNTYVGIDDKNSTAYIINIDQPGFGLPSRDYYFSETESYVKAREAYKDFIVAIANIVRRDKAIPDDDVFVREQMEGLFNFEKKLAEASTPDENRTDITLIYHKMSLSELSTNYSIGNFSWLTYMKDIFIDIK-DISSAENIVVYAPEYL---IK-LKTILEDETPSTI-QNYIVWMLTVEHVESLSQKFKDARAEFRKALYGTTSDKARWRSCSSYVNNILSNAVGALYVEEAFAGDSKKVVQELVKWIREVFISNLDKITWMDDATKGRARDKAFAIVERIGYPEFIVDKNDPKIDEEYADLAYSTTEYFANTLASLAFDSKRRLARINTAVDKNEWISGAAVVNAFYSSSYNQIVFPAGILQPPFFGLDQAMSLNFGGIGMVIGHEIIHGFDDSGRNFDKDGNLVDWWSAESAKNFKQKSQCIIDQYGNFQWDLAGGQNLSGINTLGENIADNGGIRQAYEAYMAWVKDNGEELPLPGLHLSHQQLFFLNFAQVWCGDYRPEYASNSIKTDVHSPGKFRVIGSLQNFEKFSEAYQCKASDAMNPRSKCHVW 707
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Sea Lamprey
Match: mmel1 (membrane metallo-endopeptidase-like 1 [Source:ZFIN;Acc:ZDB-GENE-101112-2])

HSP 1 Score: 263.077 bits (671), Expect = 1.443e-78
Identity = 160/561 (28.52%), Postives = 287/561 (51.16%), Query Frame = 3 
Query:  306 MNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKES-RNKISHPI------ILE-----VAKEISNGNDFELN-LIKLLKSGLGSR-FFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLID-------EILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFP--SISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLI--SETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYV 1913
            MN +A+PCD+F  + CG   K   I      + +F  +   +   LK LLE+ + +       KA   Y SCM++E+   + S P+      +LE     V    + G+ + L  ++  + S  G+R    + +A D  + + + + I +P+  L        +    ++  +Y++ M  V  I+   K   + ID        + +L + +A+A+    +++D  K  N++++  +Q++FP    +W   INEV +   I+++  ++++  + EYL+    IL  +        ++     W +I+ ++   S+   EA  E      GV   +  W+ CV   ++ L   VG ++V   F    K  +E MI+ ++ A  + ++ +TWMD  T++ A EK  AI  ++GY D ++  +   L ++YA      +    N L  LEF+ +  LK + +  S  EW +G   +NA+Y+P  N+IVFPA IL+ PF+ +G  ++ N+GGIG+VIGHEI HGFD  G KFD +G L +WWT  S +++ S+++C+++QY+SY 
Sbjct:    8 MNPAANPCDNFYEFACGGWPKKQVIPEDSGYYGTFHVLDDHLEIVLKRLLEEAAGSGDRDAVTKAKRLYLSCMDEEAIEERDSEPLLWLLEDVLEWPVATVDWNSTYGSQWRLEEVLAFMTSRYGNRVIIDVGIASDVNDSKSSAIYIDQPSLGLPTRDFYFDKGYYSQVRDTYLRAMIAVATIIRADKNITDDIDFVQEQMEGVFRLEMEIAEAITPAENRTDVTKLFNRMTLLQLQQEFPLNGFNWTLFINEVLKTVDIEVEASEEILVSAPEYLEQLSDILNSHPPSDVHNYVV-----WILITEVIGSLSHKYQEAIAETQKMLYGVLLARARWRHCVDYVNTALPSAVGALYVLDAFPRHGKTKVEMMIERLREAFIHTLDEMTWMDDRTRARAREKALAITTQMGYADYIVDGNNPRLDEEYADLNYEEDVHFENTLQDLEFAVKNELKRLRRTTSKQEWDIGPATINAFYHPSKNQIVFPAGILQPPFFGLGQAMSLNFGGIGMVIGHEITHGFDNFGRKFDKEGNLVDWWTAESDEDFDSRSRCLVSQYSSYT 563
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Sea Lamprey
Match: ecel1 (endothelin converting enzyme-like 1 [Source:ZFIN;Acc:ZDB-GENE-130530-692])

HSP 1 Score: 260.381 bits (664), Expect = 3.812e-78
Identity = 157/515 (30.49%), Postives = 265/515 (51.46%), Query Frame = 3 
Query:  750 SESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIAD--QSDPEKYTNKLSIRDMQKKFPS---ISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRV---ALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKY---RINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
             +  S ++I +Y   M K+  +LG ++   + ++++ +   +LA    S +D  + D     NK+ +RD+    P+   I+W + + ++F     ++ ED+++V  +  Y    IK L   L     R +L   + W V+  L +  S     A  +F  E  G + + +  + C+   +     ++G +FV+  F    K+ ++ M++ IK A    +E L WMD  TK +A  K + +   IGYP+ L     + K+Y   E++  ++  N L  +EF+    +  + +K+  + W +  Q +NAYY P  N++VFPA IL+   YD   P + NYGGIG +IGHE+ HG+D  G ++D  G L++WWT  S  ++L +T+C++  Y ++ IN + +    T+GE+IAD  G++++Y A      VRE    P +   A + EQLFFV   ++WC       +  QL  D HS   Y   R+ G  S   EF +VF+C R   M+ Q KC VW
Sbjct:   17 QDEESLKVIKAYKVLMNKITTLLG-ARNARHKLEDVFEFEQQLANITLSESDPLRRDINNMYNKMKLRDLHHLAPAHDQINWRQFLEQIFRK---RISEDEEVVVLATTY----IKKLSHLLSTTPVR-VLHNYMLWRVVIVLSTHLSPPFRAALHDFSREVDGAEKEVDLERLCLAQANKYFGMVLGALFVREHFSLHSKQRVQQMVEDIKHAFDQRLEELGWMDEKTKDAARGKFQLMMDMIGYPEFLGRMDEVDKEYG-FEVNEKSYFKNILNSIEFNINVSIHKIHQKVERNVWLLPPQTLNAYYLPTHNQMVFPAGILQPTLYDPEFPQSMNYGGIGTIIGHELTHGYDDWGGQYDRHGNLKQWWTAESYGKFLERTECVVKLYNNFTINKQNVNGKLTLGENIADMGGLKLAYHAYQKW--VRENGPEPPLQGMAYTHEQLFFVAFAQNWCMKRRPQSLYLQLLTDKHSPENYSRRRVLGSASQFDEFGRVFHCRRGSPMSPQHKCSVW 519
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Sea Lamprey
Match: mmel1 (membrane metallo-endopeptidase-like 1 [Source:ZFIN;Acc:ZDB-GENE-101112-2])

HSP 1 Score: 261.151 bits (666), Expect = 6.247e-78
Identity = 160/566 (28.27%), Postives = 287/566 (50.71%), Query Frame = 3 
Query:  306 MNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKES-RNKISHPI------ILE-----VAKEISNGNDFELN-LIKLLKSGLGSR-FFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLID-------EILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFP-------SISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLI--SETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYV 1913
            MN +A+PCD+F  + CG   K   I      + +F  +   +   LK LLE+ + +       KA   Y SCM++E+   + S P+      +LE     V    + G+ + L  ++  + S  G+R    + +A D  + + + + I +P+  L        +    ++  +Y++ M  V  I+   K   + ID        + +L + +A+A+    +++D  K  N++++  +Q++FP         +W   INEV +   I+++  ++++  + EYL+    IL  +        ++     W +I+ ++   S+   EA  E      GV   +  W+ CV   ++ L   VG ++V   F    K  +E MI+ ++ A  + ++ +TWMD  T++ A EK  AI  ++GY D ++  +   L ++YA      +    N L  LEF+ +  LK + +  S  EW +G   +NA+Y+P  N+IVFPA IL+ PF+ +G  ++ N+GGIG+VIGHEI HGFD  G KFD +G L +WWT  S +++ S+++C+++QY+SY 
Sbjct:    8 MNPAANPCDNFYEFACGGWPKKQVIPEDSGYYGTFHVLDDHLEIVLKRLLEEAAGSGDRDAVTKAKRLYLSCMDEEAIEERDSEPLLWLLEDVLEWPVATVDWNSTYGSQWRLEEVLAFMTSRYGNRVIIDVGIASDVNDSKSSAIYIDQPSLGLPTRDFYFDKGYYSQVRDTYLRAMIAVATIIRADKNITDDIDFVQEQMEGVFRLEMEIAEAITPAENRTDVTKLFNRMTLLQLQQEFPLNKLREQGFNWTLFINEVLKTVDIEVEASEEILVSAPEYLEQLSDILNSHPPSDVHNYVV-----WILITEVIGSLSHKYQEAIAETQKMLYGVLLARARWRHCVDYVNTALPSAVGALYVLDAFPRHGKTKVEMMIERLREAFIHTLDEMTWMDDRTRARAREKALAITTQMGYADYIVDGNNPRLDEEYADLNYEEDVHFENTLQDLEFAVKNELKRLRRTTSKQEWDIGPATINAFYHPSKNQIVFPAGILQPPFFGLGQAMSLNFGGIGMVIGHEITHGFDNFGRKFDKEGNLVDWWTAESDEDFDSRSRCLVSQYSSYT 568
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004622.1 (pep scaffold:Pmarinus_7.0:GL480748:697:25272:-1 gene:ENSPMAG00000004207.1 transcript:ENSPMAT00000004622.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 187.193 bits (474), Expect = 1.964e-52
Identity = 120/430 (27.91%), Postives = 219/430 (50.93%), Query Frame = 3 
Query:  951 MQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLG--VKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLS-NEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQ-GSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFA-ANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNY---IDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNC 2216
            +QK  P ++W   ++ +F N      E   L   S+ Y     K L  Y+     + +    L W +I  ++ +      +A    M+E++    +     W+ C+ +   +L   +G +F   +    +K+D++ MID +K A K+ +++L WMD+ T+ +A EK K I+  +G  D +   + +   Y   ++    F    + F  +++   ++++    +  +W   +Q V+A+Y   S N +  PA I++ PFY    P+   Y GIG VIGHE+ HGFD + GS+++ +G    WW  ++ +E+  +T C+  QY++Y    +P+   QT+GE+IADN G+  +  A A  + +  ++  LP + L+ +Q FFV   + WC++  ++    I+D L  D HS    R+ G +SN P F++ F C
Sbjct:    1 LQKAIPFLNWTLYLSGLFSNGTY---ETQPLFIDSVPYF----KKLSDYVKKSDPKTLTNYAL-WMLIQKMIPILDYRFRKA-ALIMAEAIDETTESPVRRWEFCMDLADKSLAYALGEIFAMKEITAKRKEDVKKMIDNLKHAFKDNLDHLPWMDNKTRLAAKEKAKNIQSAVGEDDYMEDVSNVDMFYENFKVVEGRFFETMVNFYNYTSRRTIRSM--LATSMQWRAPAQTVDAFYYYESLNTMYIPAGIMQEPFYQDVYPMFLKYAGIGTVIGHELCHGFDNKAGSEYNVEGKQENWWENTTHNEFKLRTHCMEVQYSNYTWKERPINGTQTLGENIADNGGLHTALLAYARWEEQHGKEEPLPYLNLTNKQAFFVWFAQLWCSMEKESVEVEIEDALS-DSHSPAAVRVRGMVSNSPAFAEAFTC 418
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Nematostella
Match: EDO41736 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3J6])

HSP 1 Score: 330.102 bits (845), Expect = 2.549e-102
Identity = 212/698 (30.37%), Postives = 354/698 (50.72%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIY------YQSCMNKESRNKISHPIILEVAKEISNGN----------DFELNLIKLLK--SGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLT---KKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFP-FYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLL--REWWTKSSRDEYLSKTQCIINQYASYVINNK-PLPSLQTVGEDIADNAGMRMSYFAANSKLEVR--EKLTLPRVALSPEQLFFVGMGRSWC--AIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            VC T+ C  +   +N  ++ S  PC DF  ++CG   +   I    +++ +FT++++ V  +L+ +LE+  +A    P A   +       Y+SCM+  + +K+    I ++ KEI + +          D    L+ + K  +  G   FS+ V+ D      +I+ I +    L     R+  + S +II +Y KY+  V  +L   +  E    EI+ L  +LA    S+ D    E + N+++I+D+ K+ P   W+  +N++F     K+K+ ++++  +L YL   IK++     +   + +L   + W VI   VS  S    +    +    LG KG ++ WK CV  T+  + +++G  +++  F    K     MI  ++ A K+ + ++ WMD  TK +  EK  +++ ++GYP  L          KKY    M  N    N +  L+ + +  LK + K +  +EW M  Q +NA Y+   NE++ PAAIL+ P FY  G P + ++G IG ++GHE+ HGFD  G KF+  G L    WW+  S   +  K +CI NQY+ Y ++ K PL    T+GE+IADN G + SY A ++ L+ +  E  +LP + L+ EQLF+VG G+++C  +  T+ Y+      D HS  K+R+ G +SN  EFSK F C     MN   KC VW
Sbjct:    1 VCHTKDCYSVARHINDSIDFSVSPCTDFYQFVCGGWMQKNPIPRSSSTYSTFTKLNTKVEKSLRGILEEGISA---IPGASKKLMRMPSDVYESCMDLGTIDKLGDQPIRDMIKEIGSWSLEKGWVEKDWDLSETLLYIHKKYTSAGGPLFSVHVSDDPIKNTRHIIEIDQAGPSLS----REVYTDSPKIIKAYKKYIIDVGTLLRGKEAMEKYAQEIIDLETKLANI--SVPDADKTETWFNRMTIKDLMKEAPGYDWLDHLNKMFAPE--KIKDSEQIIVPALPYLKKMIKLI-----ENTPKRVLSNYVVWNVIQDEVSFLSKPYRDVRLRYRERVLGSKGHKKRWKTCVMYTNELVGDVLGAAYIQHHFDQHSKNIARDMIKEVRQAFKDNVNSIPWMDKTTKIAVSEKADSMKDEVGYPAYLKGGKKFIKRFKKYKGVTMKNNALFANRIAILKMAHKRMLKKLRKPVDKEEWPMDPQTINAMYSFNENEMIIPAAILQPPFFYPKGSPSSLSFGAIGSILGHEMTHGFDNTGRKFNKNGELTTSNWWSDGSLKGFDEKAKCIENQYSQYKVDGKYPLNGKLTLGENIADNGGFKSSYRAYHNWLKKKGDETWSLPGLNLTSEQLFYVGFGQAYCSNSRSTEQYL--ATLSDRHSEEKFRVIGTLSNSYEFSKAFGCRPEAPMNPVTKCSVW 680
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Nematostella
Match: EDO41501 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4D9])

HSP 1 Score: 327.02 bits (837), Expect = 5.896e-101
Identity = 208/696 (29.89%), Postives = 346/696 (49.71%), Query Frame = 3 
Query:  243 YEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNK---ESRNKIS-HPIILEVAK-EISNGN-------DFE--LNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSE----SSSKEIIASYIKYMKKVLNILG---ISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSAL-EKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLT-LPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            Y+  +CET+ C      +   M+++ +PC DF  Y CG   K   +  G + + +F Q++     TLK + ++   A+      K   YY SC NK   E R+      +I +V    ++ G+       +FE  L+L+  LKS   +  F + VA D  N   NI+ I +        TL D E    + S +++  Y ++M K+  +L       T   L+DEI +   +LA+           +K  +K+++ D+Q+  P+I W+  +N +F      +  D+ +V ++  +L S   ++      R  R IL   + W +I  L +  S    EA  + M   +GV+     WK CV  T + L    G+++VK       K+  + +I  IK A  + +  +TWMD  TK+ A  EK++++   IGYPD ++    L   Y    ++      N+L    F  ++ ++  GK +   EW M   +VNAYY+  +N I FP+ IL+ PF+D   P   NYG +G+V+GHE+ HGFD++G  FD  G L  WW   S + +     C++ QY+++ + +  +   QT+ E+IADN G+R+++ A     +  EK   LP + LS +QLFF+G  + WC+  TKN +   L  D HS  + R++  +SN  +F++ ++C  +  MN  KKC VW
Sbjct:   31 YQNPICETKGCISAAFSILNKMDETVNPCRDFYQYACGKWLKDSVVPAGNSKWSAFHQVAEQNLRTLKKIFDRDDFASNGDIFRKVRDYYSSCTNKSIIEERDAAPLKKLISDVGSWSVTGGHTWTAETWNFEQALSLMHKLKS---TPLFYMFVAADDKNSSQNIIQIQQAGI-----TLSDREYYTRNESDKVVKKYKEFMVKIATLLNGATADSTTGILMDEIFQFEKKLAEIYEPKERLRHSDKIYHKMTVEDLQQLAPAIPWMDYMNNLF---STPVGHDEPVVVYTPTFLKSMSDLVI-----RTDRRILANYMVWHLIKPLTTELSKPYREAALDLMRVEMGVESGAPTWKSCVTKTDTVLGYATGHLYVKQHDGKDVKEKAKQVIQSIKEAFISNLPTVTWMDEGTKTKARGEKMESVLDLIGYPDWIMDVAQLNAYYVNLVITPEMSFENHLNARRFVHQQTMEKRGKAVDRKEWHMTPVDVNAYYSLPNNYIAFPSGILQRPFFDPEFPQAMNYGAVGMVMGHELTHGFDSKGRLFDKNGNLESWWKNQSVEAFEEHVSCMVEQYSNFTVADVKVDGKQTLDENIADNGGLRLAFQAHRQWDKENEKQPRLPGLELSRDQLFFLGFAQLWCSSSTKNSMHHPLLTDSHSPDRIRVHAAVSNSEQFAEAYDCPLDTPMNPAKKCRVW 710
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Nematostella
Match: EDO49684 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFZ0])

HSP 1 Score: 312.768 bits (800), Expect = 6.447e-96
Identity = 200/691 (28.94%), Postives = 342/691 (49.49%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQS---TANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISN---GNDFELN--------LIKLLKSGL--GSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKG-LLREWWTKSSRDEYLSKTQCIINQYASYVINNK-PLPSLQTVGEDIADNAGMRMSYFAANSKLE--VREKLTLPRVALSPEQLFFVGMGRSWC--AIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            VC+   C+++   +   ++    PC DF  + CGN  + + I    N F +FT++S  +   L++LLE  S   T   +Q   KA  +Y+SCM+ ++  ++    ++++ +++ +    ND   N        +++ L+S     S FFS+EV  D  N   +++ + +    L     R+      E++ +Y++YM KV  +LGI       + +I+    +LA    S  D++D      ++ +  + K  P   W++ +  +F   G  + + D ++A    YL     I+K        +E+L   + W +I   +SL S    +A   F  +  GVK ++  W+ C  +T+  L   +G ++V+  F  S    I+ MI  IK   K  ++   W+D  T     +K  A+R KIGY + ++    L K++   ++    F  N +   ++     +  + K +  ++W M  Q +NA Y    NEI      LR  F  + L ++ +YG +G +IGHE+ HGFD  G KFD  G +++EWW+KSS   + ++ QCI +QY+ + I NK PL  + T+ E+IADN G ++SY A +  L+    ++  LP +  + EQLFF+G  + +C  A     YI      D+HS  K+R+ G +SNM EFS  F C     MN +KKC VW
Sbjct:    1 VCQEPECQQIATLIRDAIDTDTPPCKDFFKFSCGNWVRKHPIPRSYNDFSTFTKVSKDIEDQLRELLETPSYIETLPENQALRKAKDFYRSCMDTKTIERLGTRPLMKLIRQLGSWSLCNDKSWNKEKWDAYDVLRKLQSTYYPASPFFSVEVTNDHLNSTRHLIKVDQSGLSLQ----REIYFKHPEMVDTYVEYMAKVATLLGIKGNATKEMRKIVDFETKLANITTSAEDKAD--GIYRRIKLHHLIKLVPGFPWLKHMQAIFR--GAHVTDADVVLATPSTYLSKMNDIIK-----ETPKELLSNYVVWQMIRDKISLLSKPFRKARAVFNHKISGVKEQEPRWRTCTSITNDNLGVPLGTLYVRKYFNESTVGKIQLMIQEIKDTFKERVKEHEWIDDKTTQYVFQKADALRSKIGYANYVLRPIILKKRFKSLKIGKKTFFSNNVNVDKWVRHRLVGKLRKAVDKEKWPMFPQTINAMYQFYENEIGGGRGCLRRVFLALALALSLSYGAVGSIIGHEMTHGFDNTGRKFDKNGDIVQEWWSKSSLTNFKNRAQCIADQYSKFKIQNKYPLSGVVTLDENIADNGGTKLSYNAYHRWLKDNGNQEQVLPGLKYTNEQLFFIGYAQEYCSHARPKTEYIASL--SDIHSPPKFRVIGTLSNMEEFSDAFKCPPGSPMNPKKKCEVW 676
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Nematostella
Match: EDO35107 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMH5])

HSP 1 Score: 312.383 bits (799), Expect = 7.998e-96
Identity = 197/677 (29.10%), Postives = 331/677 (48.89%), Query Frame = 3 
Query:  300 KIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQA---KAAIYYQSCMNKESRNKISHPIILEVAK-----EISNGN------DFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKA----LPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLE----VREKLTLPRV-ALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            K MN + DPCDDF  Y CG  +    I   ++S+  F  +S+     LK L+  +   ++ +      KA  YY +CM+++   K+    + ++ K      ++N N      DF    + + +    + +F++ V  D  +    ++   +   +L    +  + +   +I  +Y + M  ++  LG     E  ++E+ +L + LAK      PS+       +  N+     +      ++    +  +F  T   +K+D ++V +++EY+   + + +++    K+  I+   + W V     S  S    +   E+     G +G+   W+ C    S T    +G +FV   F+   K   E MI  I+    + ++NL WMD  T+  A EK +AIR  IGYPD + ++T L  +Y+   +    +  N     +F  ++ +  +GK +   +W+M    VNAYY+   N+IVFPA IL+ PFY+   P + NYGGIG+V+GHEI HGFD  G KF+  G L  WWT +S + +  KT C++ QY+SY  + K L  LQT+GE+IADN G++ S F A  K +    V E+  LP +  LS +QLFF+   + WC+          ++  VHS  K R+ G +SN  EF++ + C     MN + KC VW
Sbjct:    2 KSMNTTIDPCDDFYQYACGGWETKNLIPDTRSSWSQFRILSNRNEELLKKLINSKDIRDKYKDNPAVMKAFDYYDACMDEKLIEKLGQQPLQDLIKMFGSWNVTNKNWTEADWDFMKTFVMIQRDLSIAPWFNMFVGTDLKDSTKTVIVFDQSGTILSREAMLFNTTYHAKIRTAYRRIMTSLMEKLGAGNEAEARMEEVYQLELELAKVKQRIQPSLIHLLSKVRQNNQPRTLKLAPPPSFLNLTDFLGHIFNLTDYNVKQDTEVVVYAMEYM---VNMSRIFANTPKR--IVANYMMWHVAYFFASSLSKEFRDLYYEYREAITGTRGEDPRWQDCTSGVSGTFGMAIGLLFVDQTFKKESKTSAERMIKDIRNVFIDNLQNLNWMDEKTRKVAKEKAEAIRENIGYPDFIKNKTALELEYSGVRVDKTKYFWNQYERRKFYNQKNIDELGKPVDKTKWSMNPPTVNAYYSSTDNKIVFPAGILQDPFYEGDHPNSLNYGGIGMVVGHEITHGFDDNGRKFNKDGNLLTWWTNNSIEAFKKKTDCLVKQYSSYEFHGKKLNGLQTLGENIADNGGIKQS-FQAYQKWKKDNNVEEEKRLPGLEKLSHDQLFFLSFAQIWCSAYRPEAAIRAIENGVHSPGKLRVIGSLSNSNEFAEAWKCPVGSRMNPKDKCAVW 672
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Nematostella
Match: EDO37487 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFL4])

HSP 1 Score: 275.404 bits (703), Expect = 9.676e-85
Identity = 153/432 (35.42%), Postives = 232/432 (53.70%), Query Frame = 3 
Query:  981 IRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKR-EILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCV-QMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVRE---KLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +  I +VF+     + + D+++A+  +Y  +   +L +Y         +L     W++I  ++S+  +    A   FM   +G     + W++C+ +M  + L+  +G +FV   F    +  IE M  YI+ +  + +++L WMD  TK  A EK  AI   IGYPD +     L  K       G+    N L+ ++F+ +  L  + K ++ ++W +G  +VN YYN   N IVF A IL+ PF++   P   NYGG+G+VIGHEI HGFD  G  FD  G L  WW+  +   + SKTQC+++QY +Y    K L   QT+ E+IADN G++M+Y     K   RE   +  LP + LS +QLF+VG  R WC+I T+     Q+  D HS  KYR+ GP+ N P FS+VF C +N  MN  KKC VW
Sbjct:    1 LEYIQDVFQEQDFSVNKTDQILAYPPDYYKA---VLLLYQNQTNTDPRVLDNYAMWSIIDDVISVLDSNYTNAYMAFMRSKVG-NMTVKRWEQCLLKMQQTALRMPLGLLFVDKAFPKESRASIEDMSKYIRNSFIDSVDSLPWMDGATKEKAKEKAIAIHESIGYPDYIKDPAKLEAKIQNLTF-GDRLFENTLSLIKFTVQTDLAQLKKPVNREKWELGPSQVNGYYNSRQNRIVFLAGILQPPFFNPLYPKYLNYGGLGMVIGHEITHGFDGSGRMFDKDGNLNNWWSSEASMNFNSKTQCLVHQYNTYSAFGKNLNGSQTLNENIADNGGIKMAY--EGYKAWARENSAEGALPGLGLSVDQLFYVGFARPWCSIYTEQTAILQINTDSHSYPKYRVIGPLQNDPLFSEVFKCKKNSKMNPAKKCAVW 425
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Medaka
Match: ece2b (endothelin-converting enzyme 2 [Source:NCBI gene;Acc:101164289])

HSP 1 Score: 370.163 bits (949), Expect = 3.422e-116
Identity = 204/680 (30.00%), Postives = 356/680 (52.35%), Query Frame = 3 
Query:  255 VCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGN-------DFELNLIKLLKSGLGSR-FFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENL-IDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            +C +E C  +  ++ + M++S DPC DF  + CG   +   +  G++ + +F  I       LK LLE  +    S+ + K   YY SC+N +   ++    ++++  +I   N       D  + ++K++     ++ FFS+ V+ D  N   N++ + +    L       +++++++++A+Y+ YM ++  +LG  K+   + + +IL+    LA        + D EK  +K++I ++Q   P++ W+  +      + ++L + + +V ++ EYL    +++     ++  R +L   + W ++   V+        A +  +    G K      W+ C+  T  TL   +G +FVK+ F    K+  E MI+ I++A K  ++ L+WMD  T+ +A EK  +I   IG+P+ ++    L   Y   E+S ++F  N L F  FS       + K  + D+W+M    VNAYY P  N IVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D +G LR WW  SS + +  +T+C++ QY  Y +N + +   QT+GE+IADN G++ +Y A  S ++   ++  LP V L+ +QLFFVG  + WC++ T     + L  D HS  +YR+ G ++N P+FS+ F C     MN  K C VW
Sbjct:   91 LCLSEACITVASQIVEAMDRSVDPCQDFYQFACGGWMRKNPLPDGRSRWSTFNSIWGQNQALLKHLLENGTFNGSSEAERKTQSYYLSCLNTQRIEELGAQPLIDLITKIGGWNMTGPWDKDNFMEVLKVVSGPYRAQPFFSVGVSADPKNSNSNVVQVDQSGLFLPSRDYYLNKTANEKVLAAYLDYMVELGMLLGGEKSSTLVQMQQILEFETALANITVPQDQRRDEEKIYHKVTIAELQALAPAVDWLEFLTSSL--SPLELNDTEPVVLYAREYLQQVSELI-----NKTDRSLLNNYMMWTLVQKSVATLDQRFENAQDRLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVKATFDKLSKEIAEEMINEIRSAFKQALDRLSWMDEQTRKAAKEKADSIYDMIGFPEFILDPKELDDVYDGYEVSDDSFFQNMLNFYNFSARVMADQLRKTPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAHDHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNSSVEAFRVRTECMMEQYNRYTVNGEHVNGKQTLGENIADNGGLKAAYHAYQSWIQRNGQEKRLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPRYRVIGTLANSPDFSRHFGCPEGTPMNSGKPCEVW 763
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Medaka
Match: ece1 (endothelin converting enzyme 1 [Source:NCBI gene;Acc:101158602])

HSP 1 Score: 351.673 bits (901), Expect = 2.789e-109
Identity = 212/703 (30.16%), Postives = 362/703 (51.49%), Query Frame = 3 
Query:  186 IMKTIFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNK----ESRNKISHPIILEVAKEISNG----NDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILG-ISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFA-ANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            ++  +  V LI      K      C T  C  +   +   +++S DPC DF ++ CG   K   +  G++ +  F+ +       +K LLE  +    S+ + KA  YYQ+CMN+    E   K    +I  +     NG    ++F+  L K+  S   S FF++ V+ D+ N   N++ + + +  L       +++++++ + +Y+ ++ ++  +LG   +  + ++ EI++    LA       ++ D E   +K+ + D++   P++ WI  + EVF+   + L + + +V ++ EYL     ++     ++  + +L   +   V+  +VS+      +A + F+    G K      WK CV  T S L   +G MFVK  F    K   E M+  IK A ++ +++++WMD+ TK +A EK  AI + +GYP+ +++ T L K +   E+    +  N + +  FS       + K  + ++W+M    VNAYYNP  NE+V PA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  + QC++ QY +Y IN +PL    T+GE+IADN G++ +Y A  N   +  E+  LP + ++  QLFFVG  + WC++ T     + +  D HS  ++R+ G +SN  EFSK F C  N  MN + KC +W
Sbjct:   58 VLSVVLFVSLICAGVFYKNGHPGSCLTGPCITVAGAVMGALDRSVDPCHDFYNFACGGWVKNNPLPEGKSRWGPFSNLWEHNMLVMKHLLENTTMKGLSKAEEKAQRYYQACMNESKIEELGAKPLQQLISHLGGWALNGPWDKDNFQEVLRKVSGSLRTSPFFTVFVSTDSKNSNSNVIQVDQSSLGLPSRDYYLNKTANEKYLTAYLNFLVELGVLLGGTEEASQTMMTEIVEFETTLANITVPQEERRDEELIYHKMKVEDLKTLAPAVEWIPYLIEVFK--PVPLNQSELVVVYAKEYLQKVSDLI-----EKTNKSLLNNYMVMKVVRKMVSVLDQRFQDAEQRFLEVMYGTKKSCTPRWKLCVSDTDSALGFALGAMFVKDTFAEDSKDIAEEMVGEIKWAFEDSLKDVSWMDAETKKAAKEKADAIYNMVGYPEFIMNATKLDKVFNDFEVVSELYFQNVMQYYNFSARVTADQLRKAPNRNQWSMTPPTVNAYYNPTKNEMVLPAGILQAPFYSRSWPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQAQCMVEQYGNYSINQEPLNGKHTLGENIADNGGLKAAYKAYVNWIQKNGEEPMLPALGMTNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSREFSKHFGCRANAPMNPKHKCELW 753
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Medaka
Match: ece1 (endothelin converting enzyme 1 [Source:NCBI gene;Acc:101158602])

HSP 1 Score: 347.051 bits (889), Expect = 4.577e-108
Identity = 207/679 (30.49%), Postives = 354/679 (52.14%), Query Frame = 3 
Query:  258 CETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNK----ESRNKISHPIILEVAKEISNG----NDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILG-ISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFA-ANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            C T  C  +   +   +++S DPC DF ++ CG   K   +  G++ +  F+ +       +K LLE  +    S+ + KA  YYQ+CMN+    E   K    +I  +     NG    ++F+  L K+  S   S FF++ V+ D+ N   N++ + + +  L       +++++++ + +Y+ ++ ++  +LG   +  + ++ EI++    LA       ++ D E   +K+ + D++   P++ WI  + EVF+   + L + + +V ++ EYL     ++     ++  + +L   +   V+  +VS+      +A + F+    G K      WK CV  T S L   +G MFVK  F    K     M+  IK A ++ +++++WMD+ TK +A EK  AI + +GYP+ +++ T L K +   E+    +  N + +  FS       + K  + ++W+M    VNAYYNP  NE+V PA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  + QC++ QY +Y IN +PL    T+GE+IADN G++ +Y A  N   +  E+  LP + ++  QLFFVG  + WC++ T     + +  D HS  ++R+ G +SN  EFSK F C  N  MN + KC +W
Sbjct:   40 CLTGPCITVAGAVMGALDRSVDPCHDFYNFACGGWVKNNPLPEGKSRWGPFSNLWEHNMLVMKHLLENTTMKGLSKAEEKAQRYYQACMNESKIEELGAKPLQQLISHLGGWALNGPWDKDNFQEVLRKVSGSLRTSPFFTVFVSTDSKNSNSNVIQVDQSSLGLPSRDYYLNKTANEKYLTAYLNFLVELGVLLGGTEEASQTMMTEIVEFETTLANITVPQEERRDEELIYHKMKVEDLKTLAPAVEWIPYLIEVFK--PVPLNQSELVVVYAKEYLQKVSDLI-----EKTNKSLLNNYMVMKVVRKMVSVLDQRFQDAEQRFLEVMYGTKKSCTPRWKLCVSDTDSALGFALGAMFVKDTFAEDSKDIASEMVGEIKWAFEDSLKDVSWMDAETKKAAKEKADAIYNMVGYPEFIMNATKLDKVFNDFEVVSELYFQNVMQYYNFSARVTADQLRKAPNRNQWSMTPPTVNAYYNPTKNEMVLPAGILQAPFYSRSWPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQAQCMVEQYGNYSINQEPLNGKHTLGENIADNGGLKAAYKAYVNWIQKNGEEPMLPALGMTNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSREFSKHFGCRANAPMNPKHKCELW 711
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Medaka
Match: ece1 (endothelin converting enzyme 1 [Source:NCBI gene;Acc:101158602])

HSP 1 Score: 346.28 bits (887), Expect = 4.854e-107
Identity = 212/717 (29.57%), Postives = 362/717 (50.49%), Query Frame = 3 
Query:  186 IMKTIFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNK----ESRNKISHPIILEVAKEISNG----NDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILG-ISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVK---------------GKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFA-ANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            ++  +  V LI      K      C T  C  +   +   +++S DPC DF ++ CG   K   +  G++ +  F+ +       +K LLE  +    S+ + KA  YYQ+CMN+    E   K    +I  +     NG    ++F+  L K+  S   S FF++ V+ D+ N   N++ + + +  L       +++++++ + +Y+ ++ ++  +LG   +  + ++ EI++    LA       ++ D E   +K+ + D++   P++ WI  + EVF+   + L + + +V ++ EYL     ++     ++  + +L   +   V+  +VS+      +A + F+    G K                    WK CV  T S L   +G MFVK  F    K   E M+  IK A ++ +++++WMD+ TK +A EK  AI + +GYP+ +++ T L K +   E+    +  N + +  FS       + K  + ++W+M    VNAYYNP  NE+V PA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D  G LR WW  SS + +  + QC++ QY +Y IN +PL    T+GE+IADN G++ +Y A  N   +  E+  LP + ++  QLFFVG  + WC++ T     + +  D HS  ++R+ G +SN  EFSK F C  N  MN + KC +W
Sbjct:   71 VLSVVLFVSLICAGVFYKNGHPGSCLTGPCITVAGAVMGALDRSVDPCHDFYNFACGGWVKNNPLPEGKSRWGPFSNLWEHNMLVMKHLLENTTMKGLSKAEEKAQRYYQACMNESKIEELGAKPLQQLISHLGGWALNGPWDKDNFQEVLRKVSGSLRTSPFFTVFVSTDSKNSNSNVIQVDQSSLGLPSRDYYLNKTANEKYLTAYLNFLVELGVLLGGTEEASQTMMTEIVEFETTLANITVPQEERRDEELIYHKMKVEDLKTLAPAVEWIPYLIEVFK--PVPLNQSELVVVYAKEYLQKVSDLI-----EKTNKSLLNNYMVMKVVRKMVSVLDQRFQDAEQRFLEVMYGTKKMLGGFPGAFVDVSFSCTPRWKLCVSDTDSALGFALGAMFVKDTFAEDSKDIAEEMVGEIKWAFEDSLKDVSWMDAETKKAAKEKADAIYNMVGYPEFIMNATKLDKVFNDFEVVSELYFQNVMQYYNFSARVTADQLRKAPNRNQWSMTPPTVNAYYNPTKNEMVLPAGILQAPFYSRSWPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQAQCMVEQYGNYSINQEPLNGKHTLGENIADNGGLKAAYKAYVNWIQKNGEEPMLPALGMTNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSREFSKHFGCRANAPMNPKHKCELW 780
[Close]
BLAST of Endothelin converting enzyme 1 vs. Ensembl Medaka
Match: ece2b (endothelin-converting enzyme 2 [Source:NCBI gene;Acc:101164289])

HSP 1 Score: 328.176 bits (840), Expect = 3.957e-100
Identity = 184/605 (30.41%), Postives = 320/605 (52.89%), Query Frame = 3 
Query:  480 SQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGN-------DFELNLIKLLKSGLGSR-FFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENL-IDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK-QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVR-EKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            S+ + K   YY SC+N +   ++    ++++  +I   N       D  + ++K++     ++ FFS+ V+ D  N   N++ + +    L       +++++++++A+Y+ YM ++  +LG  K+   + + +IL+    LA        + D EK  +K++I ++Q   P++ W+  +      + ++L + + +V ++ EYL    +++     ++  R +L   + W ++   V+        A +  +    G K      W+ C+  T  TL   +G +FVK+ F    K+  E MI+ I++A K  ++ L+WMD  T+ +A EK  +I   IG+P+ ++    L   Y   E+S ++F  N L F  FS       + K  + D+W+M    VNAYY P  N IVFPA IL+ PFY    P   N+GGIGVV+GHE+ H FD QG ++D +G LR WW  SS + +  +T+C++ QY  Y +N + +   QT+GE+IADN G++ +Y A  S ++   ++  LP V L+ +QLFFVG  + WC++ T     + L  D HS  +YR+ G ++N P+FS+ F C     MN  K C VW
Sbjct:  192 SEAERKTQSYYLSCLNTQRIEELGAQPLIDLITKIGGWNMTGPWDKDNFMEVLKVVSGPYRAQPFFSVGVSADPKNSNSNVVQVDQSGLFLPSRDYYLNKTANEKVLAAYLDYMVELGMLLGGEKSSTLVQMQQILEFETALANITVPQDQRRDEEKIYHKVTIAELQALAPAVDWLEFLTSSL--SPLELNDTEPVVLYAREYLQQVSELI-----NKTDRSLLNNYMMWTLVQKSVATLDQRFENAQDRLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVKATFDKLSKEIAEEMINEIRSAFKQALDRLSWMDEQTRKAAKEKADSIYDMIGFPEFILDPKELDDVYDGYEVSDDSFFQNMLNFYNFSARVMADQLRKTPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAHDHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNSSVEAFRVRTECMMEQYNRYTVNGEHVNGKQTLGENIADNGGLKAAYHAYQSWIQRNGQEKRLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPRYRVIGTLANSPDFSRHFGCPEGTPMNSGKPCEVW 789
[Close]
BLAST of Endothelin converting enzyme 1 vs. Planmine SMEST
Match: SMESG000003230.1 (SMESG000003230.1)

HSP 1 Score: 1419.45 bits (3673), Expect = 0.000e+0
Identity = 690/691 (99.86%), Postives = 690/691 (99.86%), Query Frame = 3 
Query:  189 MKTIFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            MKTIFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKL KSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW
Sbjct:    1 MKTIFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLFKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 691
[Close]
BLAST of Endothelin converting enzyme 1 vs. Planmine SMEST
Match: SMESG000003218.1 (SMESG000003218.1)

HSP 1 Score: 1385.55 bits (3585), Expect = 0.000e+0
Identity = 674/691 (97.54%), Postives = 681/691 (98.55%), Query Frame = 3 
Query:  189 MKTIFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            MKTIFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFD FTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSI+VAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEII SYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQS+PEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLD SIKILKVYLGDRKKREILQKDLEWAVIS LV LGS+ALIEA EEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALK+VIENLTWMDSNTKSSALEKLK IRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPD+WAMG Q+VNAYYN LSNEIVFPAAI RFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYID+QLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW
Sbjct:    1 MKTIFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDYFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIDVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIITSYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSNPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDYSIKILKVYLGDRKKREILQKDLEWAVISRLVLLGSDALIEAQEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKSVIENLTWMDSNTKSSALEKLKTIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDKWAMGPQKVNAYYNALSNEIVFPAAIFRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDNQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 691
[Close]
BLAST of Endothelin converting enzyme 1 vs. Planmine SMEST
Match: SMESG000003230.1 (SMESG000003230.1)

HSP 1 Score: 1341.25 bits (3470), Expect = 0.000e+0
Identity = 651/652 (99.85%), Postives = 651/652 (99.85%), Query Frame = 3 
Query:  306 MNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            MNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKL KSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW
Sbjct:    1 MNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLFKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 652
[Close]
BLAST of Endothelin converting enzyme 1 vs. Planmine SMEST
Match: SMESG000003218.1 (SMESG000003218.1)

HSP 1 Score: 1308.89 bits (3386), Expect = 0.000e+0
Identity = 635/652 (97.39%), Postives = 642/652 (98.47%), Query Frame = 3 
Query:  306 MNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            MNKSADPCDDFSSYMCGNMDKVYSILPGQNSFD FTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSI+VAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEII SYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQS+PEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLD SIKILKVYLGDRKKREILQKDLEWAVIS LV LGS+ALIEA EEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALK+VIENLTWMDSNTKSSALEKLK IRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPD+WAMG Q+VNAYYN LSNEIVFPAAI RFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYID+QLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW
Sbjct:    1 MNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDYFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIDVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIITSYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSNPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDYSIKILKVYLGDRKKREILQKDLEWAVISRLVLLGSDALIEAQEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKSVIENLTWMDSNTKSSALEKLKTIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDKWAMGPQKVNAYYNALSNEIVFPAAIFRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDNQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 652
[Close]
BLAST of Endothelin converting enzyme 1 vs. Planmine SMEST
Match: SMESG000003235.1 (SMESG000003235.1)

HSP 1 Score: 1293.87 bits (3347), Expect = 0.000e+0
Identity = 627/691 (90.74%), Postives = 658/691 (95.22%), Query Frame = 3 
Query:  189 MKTIFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 2261
            MKTIFV+GLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKV+ ILPGQNSF+SFTQI SSVTTTLKDLLEKQSTANRSQPQ KAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPT +L EGTLR+ ESS KEIIASYIKYMKKVLNILGISK YEN+IDEILKLHIRLAKALPSIADQSDPEKYTNKLSIR+MQ+KFPSISWIRVINEV EN+  KLKEDDKLVAFSLEY DS IKILK YLGD +K++ILQ+DLEWAVISSLV LGS+ALIEANEEFMSE  G+KGKQEEWKKCVQ+TSSTLQEIVGNMFVKSQFQPSQKKDIE MIDYIKAALK+VIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAP EM+  N LGNY+ F EF+ EEYLK VG+KISPDEWAMGSQEVNAYYNP SNEIVFPAAILRFPFYDIGLPITYNYGGIG+VIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAG+RMSYFAANSKLEVREKLTLP V LSPEQLFFVG+GR+WC+IVTK++ID++LK DVHSVWKYRINGPMSNMPEFSK+FNCDRNK MNR KKCLVW
Sbjct:    1 MKTIFVIGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVFRILPGQNSFNSFTQIRSSVTTTLKDLLEKQSTANRSQPQTKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTLILSEGTLRNFESS-KEIIASYIKYMKKVLNILGISKNYENVIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRNMQQKFPSISWIRVINEVLENSDKKLKEDDKLVAFSLEYFDSLIKILKEYLGDSQKKQILQRDLEWAVISSLVPLGSDALIEANEEFMSEGFGIKGKQEEWKKCVQITSSTLQEIVGNMFVKSQFQPSQKKDIELMIDYIKAALKDVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPIEMTFKNLLGNYINFQEFAREEYLKAVGEKISPDEWAMGSQEVNAYYNPTSNEIVFPAAILRFPFYDIGLPITYNYGGIGMVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGIRMSYFAANSKLEVREKLTLPGVDLSPEQLFFVGVGRTWCSIVTKSFIDERLKGDVHSVWKYRINGPMSNMPEFSKLFNCDRNKKMNRLKKCLVW 690
The following BLAST results are available for this feature:
BLAST of Endothelin converting enzyme 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ECE11.335e-11130.69endothelin converting enzyme 1 [Source:HGNC Symbol... [more]
ECE11.782e-11130.69endothelin converting enzyme 1 [Source:HGNC Symbol... [more]
ECE11.841e-11130.69endothelin converting enzyme 1 [Source:HGNC Symbol... [more]
ECE12.524e-11130.69endothelin converting enzyme 1 [Source:HGNC Symbol... [more]
ECE23.107e-11030.00endothelin converting enzyme 2 [Source:HGNC Symbol... [more]
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nep-26.601e-8828.53Neprilysin-2 [Source:UniProtKB/Swiss-Prot;Acc:O44... [more]
nep-113.760e-8728.90Neprilysin-11 [Source:UniProtKB/Swiss-Prot;Acc:O1... [more]
nep-11.206e-8229.51Neprilysin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q18... [more]
nep-211.352e-7624.30Neprilysin-21 [Source:UniProtKB/Swiss-Prot;Acc:Q2... [more]
nep-211.352e-7624.30Neprilysin-21 [Source:UniProtKB/Swiss-Prot;Acc:Q2... [more]
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Nep33.529e-10929.64gene:FBgn0031081 transcript:FBtr0307554[more]
Nep33.529e-10929.64gene:FBgn0031081 transcript:FBtr0070000[more]
Nep33.529e-10929.64gene:FBgn0031081 transcript:FBtr0307555[more]
Nep15.715e-10429.62gene:FBgn0029843 transcript:FBtr0343930[more]
Nep15.715e-10429.62gene:FBgn0029843 transcript:FBtr0070873[more]
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ece2b2.460e-11931.09endothelin converting enzyme 2b [Source:ZFIN;Acc:Z... [more]
ece15.734e-10829.29endothelin converting enzyme 1 [Source:ZFIN;Acc:ZD... [more]
ece15.734e-10829.29endothelin converting enzyme 1 [Source:ZFIN;Acc:ZD... [more]
mmel11.773e-9728.55membrane metallo-endopeptidase-like 1 [Source:ZFIN... [more]
mmel12.491e-9728.55membrane metallo-endopeptidase-like 1 [Source:ZFIN... [more]
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dhdds2.342e-11431.18dehydrodolichyl diphosphate synthase subunit [Sour... [more]
dhdds3.056e-11431.18dehydrodolichyl diphosphate synthase subunit [Sour... [more]
dhdds3.343e-11431.18dehydrodolichyl diphosphate synthase subunit [Sour... [more]
dhdds2.210e-11231.03dehydrodolichyl diphosphate synthase subunit [Sour... [more]
dhdds3.407e-11230.94dehydrodolichyl diphosphate synthase subunit [Sour... [more]
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ece16.516e-11530.37endothelin converting enzyme 1 [Source:MGI Symbol;... [more]
Ece29.892e-11230.59endothelin converting enzyme 2 [Source:MGI Symbol;... [more]
Ece23.176e-11130.59endothelin converting enzyme 2 [Source:MGI Symbol;... [more]
Gm493336.667e-11030.59predicted gene, 49333 [Source:MGI Symbol;Acc:MGI:6... [more]
Gm493332.006e-10930.59predicted gene, 49333 [Source:MGI Symbol;Acc:MGI:6... [more]
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BLAST of Endothelin converting enzyme 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8IS64|ECE_LOCMI5.305e-12231.25Endothelin-converting enzyme homolog OS=Locusta mi... [more]
sp|Q4PZA2|ECE1_MOUSE6.400e-11430.37Endothelin-converting enzyme 1 OS=Mus musculus OX=... [more]
sp|P97739|ECE1_CAVPO1.587e-11330.70Endothelin-converting enzyme 1 OS=Cavia porcellus ... [more]
sp|P42893|ECE1_RAT3.322e-11330.37Endothelin-converting enzyme 1 OS=Rattus norvegicu... [more]
sp|F1N476|ECE2_BOVIN3.444e-11130.44Endothelin-converting enzyme 2 OS=Bos taurus OX=99... [more]
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BLAST of Endothelin converting enzyme 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2T7PT702.745e-12531.25Uncharacterized protein OS=Pomacea canaliculata OX... [more]
T1I0G91.408e-12030.32Uncharacterized protein (Fragment) OS=Rhodnius pro... [more]
A0A4S2K8711.776e-12032.51F-box domain-containing protein OS=Temnothorax lon... [more]
A0A026WJ962.670e-12031.34Endothelin-converting enzyme OS=Ooceraea biroi OX=... [more]
A0A3L8E1J03.328e-12031.34Uncharacterized protein OS=Ooceraea biroi OX=20151... [more]
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ece2b2.657e-12031.38endothelin-converting enzyme 2 [Source:NCBI gene;A... [more]
ece2b3.356e-12031.38endothelin-converting enzyme 2 [Source:NCBI gene;A... [more]
ece2b5.973e-12031.38endothelin-converting enzyme 2 [Source:NCBI gene;A... [more]
ece2b8.191e-10930.54endothelin-converting enzyme 2 [Source:NCBI gene;A... [more]
mmel11.759e-9828.98membrane metalloendopeptidase like 1 [Source:NCBI ... [more]
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mmel18.356e-9429.35membrane metallo-endopeptidase-like 1 [Source:ZFIN... [more]
mmel11.443e-7828.52membrane metallo-endopeptidase-like 1 [Source:ZFIN... [more]
ecel13.812e-7830.49endothelin converting enzyme-like 1 [Source:ZFIN;A... [more]
mmel16.247e-7828.27membrane metallo-endopeptidase-like 1 [Source:ZFIN... [more]
ENSPMAT00000004622.11.964e-5227.91pep scaffold:Pmarinus_7.0:GL480748:697:25272:-1 ge... [more]
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO417362.549e-10230.37Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO415015.896e-10129.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO496846.447e-9628.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO351077.998e-9629.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO374879.676e-8535.42Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Endothelin converting enzyme 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ece2b3.422e-11630.00endothelin-converting enzyme 2 [Source:NCBI gene;A... [more]
ece12.789e-10930.16endothelin converting enzyme 1 [Source:NCBI gene;A... [more]
ece14.577e-10830.49endothelin converting enzyme 1 [Source:NCBI gene;A... [more]
ece14.854e-10729.57endothelin converting enzyme 1 [Source:NCBI gene;A... [more]
ece2b3.957e-10030.41endothelin-converting enzyme 2 [Source:NCBI gene;A... [more]
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BLAST of Endothelin converting enzyme 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000003230.10.000e+099.86SMESG000003230.1[more]
SMESG000003218.10.000e+097.54SMESG000003218.1[more]
SMESG000003230.10.000e+099.85SMESG000003230.1[more]
SMESG000003218.10.000e+097.39SMESG000003218.1[more]
SMESG000003235.10.000e+090.74SMESG000003235.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022629 ID=SMED30022629|Name=Endothelin converting enzyme 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2375bp
CATATAATCAACTATAAATAAGAATTGAGGACCTGTAGTGATTGGAATCA
AAAGTTGTTAGATTGTAAATTTAGTCGGAATTTGTTGATTGGTAAATAAA
AGTCATTTTAGTTTATCTACTGTACAAACAAAAATTCAACAAGAAAACTT
TCCTAAATATACATTTGAAATTAAACAATTTTAAAATAATGAAAACCATT
TTTGTAGTCGGTCTGATAGCAATTTTGTCGCTATGCAAATTATACGAAGG
TAAAGTTTGTGAAACCGAAATATGCAAAAAGCTTGGAGAAGAACTCAACA
AAATAATGAACAAATCTGCAGATCCTTGCGACGATTTTAGTTCATATATG
TGTGGAAATATGGATAAAGTTTATTCGATTTTACCGGGACAAAATTCGTT
TGATTCCTTTACGCAAATTAGCTCATCAGTCACGACAACATTGAAGGACC
TTCTTGAGAAACAATCGACAGCCAATCGGTCTCAACCTCAAGCGAAAGCT
GCGATTTATTATCAGTCATGCATGAATAAAGAAAGTCGCAACAAAATAAG
TCATCCAATTATATTGGAAGTTGCAAAAGAAATATCAAATGGGAACGATT
TCGAATTGAATTTAATAAAGCTACTTAAGTCCGGTTTGGGATCTCGATTT
TTCTCCATTGAAGTTGCTCAAGATGCGGCGAATCCTGAATATAATATTTT
AAATATTGGTAAGCCAACATTCGTTTTATTGGAAGGAACTCTGAGGGATT
CTGAATCTTCTTCCAAAGAAATAATAGCTAGTTACATAAAATATATGAAA
AAAGTCCTAAACATTTTGGGAATTTCAAAAACTTACGAAAACCTAATTGA
TGAAATCCTAAAATTACACATTAGACTGGCAAAAGCCCTCCCGAGTATTG
CTGATCAAAGTGATCCAGAAAAATACACGAACAAACTATCAATTCGTGAC
ATGCAAAAAAAATTTCCATCGATTTCATGGATCCGGGTTATCAACGAAGT
TTTCGAAAATACTGGTATTAAGCTAAAAGAAGATGATAAATTGGTTGCAT
TCTCTCTGGAATACCTGGATTCTTCTATTAAAATTCTTAAAGTATACTTA
GGTGATCGGAAAAAGAGAGAAATTCTACAAAAGGATTTGGAATGGGCCGT
GATATCAAGTTTGGTGTCATTAGGATCCAATGCTCTCATTGAAGCAAACG
AAGAATTTATGAGTGAAAGTCTTGGTGTCAAAGGAAAGCAAGAAGAATGG
AAGAAATGTGTTCAAATGACTTCGTCAACTTTACAGGAAATAGTAGGAAA
TATGTTCGTAAAATCTCAATTTCAACCTTCACAGAAAAAGGATATCGAGT
CAATGATTGACTATATCAAGGCGGCACTGAAAAATGTGATTGAAAATCTC
ACCTGGATGGATTCGAATACGAAATCAAGTGCTTTGGAAAAGTTGAAAGC
AATTCGACACAAAATCGGATATCCGGACTCATTGATATCGGAAACATATC
TTACAAAGAAATATGCTCCAACTGAAATGAGTGGCAATAATTTTCTAGGA
AATTATCTTACTTTCCTAGAATTCTCTACTGAAGAATACCTAAAGACTGT
CGGAAAAAAGATTTCACCTGATGAATGGGCTATGGGTTCACAAGAGGTCA
ATGCCTACTACAATCCATTGTCAAATGAAATTGTTTTCCCGGCGGCAATT
TTGCGTTTTCCATTTTACGACATTGGACTACCAATAACTTACAATTACGG
AGGAATCGGAGTGGTTATTGGTCATGAGATTCTACACGGATTTGATACAC
AAGGATCAAAATTCGATTCCAAAGGTCTTTTGAGAGAATGGTGGACAAAA
TCTAGCAGAGATGAATATTTGAGCAAAACTCAGTGCATTATTAACCAATA
TGCCAGTTATGTCATCAATAATAAACCGTTACCTTCATTGCAAACCGTGG
GAGAAGATATTGCTGACAACGCAGGAATGAGGATGTCCTATTTTGCAGCC
AATTCTAAACTGGAAGTGCGGGAGAAGTTAACCCTTCCACGGGTTGCATT
GAGTCCTGAACAGTTGTTCTTTGTTGGCATGGGAAGATCCTGGTGCGCAA
TCGTTACTAAAAACTATATTGATGACCAACTGAAAGAAGATGTTCACAGC
GTTTGGAAATACAGAATTAATGGTCCCATGTCAAACATGCCAGAGTTCTC
CAAGGTTTTCAACTGCGACAGAAATAAAAATATGAACAGACAAAAGAAAT
GTTTGGTTTGGTGATACAATATCAAATTTCAACAATAATATTTGACTATA
TTTAATAAATAATCTTTAGGTTTGTTAAAAAGTTTTTCAAAAAAATTAAT
AAATAAATCTGAGTTTGAAAAAAAA
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protein sequence of SMED30022629-orf-1

>SMED30022629-orf-1 ID=SMED30022629-orf-1|Name=SMED30022629-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=692bp
MKTIFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDF
SSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQP
QAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGL
GSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESSSKEIIASYI
KYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKL
SIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKIL
KVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGK
QEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNV
IENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGN
NFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVF
PAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLRE
WWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMS
YFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKE
DVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0048703embryonic viscerocranium morphogenesis
GO:0006508proteolysis
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR042089Peptidase_M13_dom_2
IPR000718Peptidase_M13
IPR018497Peptidase_M13_C
IPR024079MetalloPept_cat_dom_sf
IPR008753Peptidase_M13_N
Vocabulary: molecular function
TermDefinition
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR018497Peptidase M13, C-terminal domainPRINTSPR00786NEPRILYSINcoord: 589..600
score: 48.85
coord: 498..510
score: 61.27
coord: 480..492
score: 52.52
coord: 519..535
score: 74.44
IPR018497Peptidase M13, C-terminal domainPFAMPF01431Peptidase_M13coord: 488..689
e-value: 2.2E-58
score: 197.2
IPR024079Metallopeptidase, catalytic domain superfamilyGENE3DG3DSA:3.40.390.10coord: 29..691
e-value: 9.7E-190
score: 634.4
IPR008753Peptidase M13, N-terminal domainPFAMPF05649Peptidase_M13_Ncoord: 46..429
e-value: 1.3E-78
score: 265.3
IPR042089Peptidase M13, domain 2GENE3DG3DSA:1.10.1380.10coord: 72..475
e-value: 9.7E-190
score: 634.4
IPR000718Peptidase M13PANTHERPTHR11733ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATEDcoord: 23..688
IPR000718Peptidase M13CDDcd08662M13coord: 44..688
e-value: 0.0
score: 581.249
NoneNo IPR availablePROSITEPS51885NEPRILYSINcoord: 23..691
score: 97.237
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.694
NoneNo IPR availableSUPERFAMILYSSF55486Metalloproteases ("zincins"), catalytic domaincoord: 23..691