Centrosomal protein 350
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30022622 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of Centrosomal protein 350 vs. Ensembl Human
Match: CEP350 (centrosomal protein 350 [Source:HGNC Symbol;Acc:HGNC:24238]) HSP 1 Score: 54.299 bits (129), Expect = 2.106e-6 Identity = 43/145 (29.66%), Postives = 77/145 (53.10%), Query Frame = 1 Query: 4501 TTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQS---KIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 +T V K+ VF + EI EIF+ + +L QP W+ + N+ Y ++ + P + D ++ + V L + K KE ++ K++K+ R+++D VD +L+ +L +EE +W+ YD+ E VK Q+A+ IF Sbjct: 429 STSKRVYKQAVFDLTKEIFEEIFAEDPNLNQPVWMKPCRI--NSSY--FRRVKNPNNLDEIKSFIASEVLKLFSLK-----------KEPNHKTDWQKMMKFG-RKKRDRVDHILVQELHEEEAQWVNYDEDELCVKMQLADGIF 557
BLAST of Centrosomal protein 350 vs. Ensembl Human
Match: CEP350 (centrosomal protein 350 [Source:HGNC Symbol;Acc:HGNC:24238]) HSP 1 Score: 53.9138 bits (128), Expect = 3.161e-6 Identity = 43/145 (29.66%), Postives = 77/145 (53.10%), Query Frame = 1 Query: 4501 TTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQS---KIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 +T V K+ VF + EI EIF+ + +L QP W+ + N+ Y ++ + P + D ++ + V L + K KE ++ K++K+ R+++D VD +L+ +L +EE +W+ YD+ E VK Q+A+ IF Sbjct: 1140 STSKRVYKQAVFDLTKEIFEEIFAEDPNLNQPVWMKPCRI--NSSY--FRRVKNPNNLDEIKSFIASEVLKLFSLK-----------KEPNHKTDWQKMMKFG-RKKRDRVDHILVQELHEEEAQWVNYDEDELCVKMQLADGIF 1268
BLAST of Centrosomal protein 350 vs. Ensembl Human
Match: CEP350 (centrosomal protein 350 [Source:HGNC Symbol;Acc:HGNC:24238]) HSP 1 Score: 53.5286 bits (127), Expect = 5.238e-6 Identity = 43/145 (29.66%), Postives = 77/145 (53.10%), Query Frame = 1 Query: 4501 TTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQS---KIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 +T V K+ VF + EI EIF+ + +L QP W+ + N+ Y ++ + P + D ++ + V L + K KE ++ K++K+ R+++D VD +L+ +L +EE +W+ YD+ E VK Q+A+ IF Sbjct: 2965 STSKRVYKQAVFDLTKEIFEEIFAEDPNLNQPVWMKPCRI--NSSY--FRRVKNPNNLDEIKSFIASEVLKLFSLK-----------KEPNHKTDWQKMMKFG-RKKRDRVDHILVQELHEEEAQWVNYDEDELCVKMQLADGIF 3093
BLAST of Centrosomal protein 350 vs. Ensembl Mouse
Match: Cep350 (centrosomal protein 350 [Source:MGI Symbol;Acc:MGI:1921331]) HSP 1 Score: 54.299 bits (129), Expect = 2.081e-6 Identity = 56/214 (26.17%), Postives = 103/214 (48.13%), Query Frame = 1 Query: 4306 IPLNSENIEPLVESATRYLLEYKKK----HGFIADTAFSDEENELPDLYVDTEPITNEEEIFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQS---KIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 +P +E +E LV +A L ++K+ HG T F ++ D+ +T+R V K+ VF + EI EIF+ + ++ QP W+ + N+ Y ++ + P + D ++ + V L++ K KE ++ K++K+ R+++D VD +L+ +L +EE +W+ YD+ E VK Q+A+ IF Sbjct: 2894 VPHTAEEVESLVHNAAEELWKWKELGQDLHGLSLPTTFLGGASKGLDIG-------------------STSR-RVYKQAVFDLTKEIFEEIFAEDPNVNQPVWMKPCRI--NSSY--FRRVKNPNNLDEIKHFITTEVLKLLSLK-----------KEPNHKTDWQKMMKFG-RKKRDRVDHILVQELHEEEAQWVNYDEDELCVKMQLADGIF 3071
BLAST of Centrosomal protein 350 vs. TrEMBL
Match: K1PSG8 (CAP-Gly domain-containing protein OS=Crassostrea gigas OX=29159 GN=CGI_10015427 PE=4 SV=1) HSP 1 Score: 69.707 bits (169), Expect = 7.802e-8 Identity = 45/139 (32.37%), Postives = 72/139 (51.80%), Query Frame = 1 Query: 4513 HVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERV-DVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 V K+++F + E+L EI+ E P W K ++G PP+ D + IV+E V D+L G G+++ + KW +R++KD VD +L+ +LR+EE EW+ YD+ E VK Q+ + IF Sbjct: 995 RVYKKLLFDLTGELLKEIYKNELKEDPPPWQKP----KQRRQKYFRGASPPKGVDTLTPIVQEAVIDML----------GLNGSRKLDRN----KWNVRKKKDHVDNILVQELREEEPEWVNYDNDEIAVKMQLTDNIF 1115
BLAST of Centrosomal protein 350 vs. TrEMBL
Match: A0A2T7NM33 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_18044 PE=4 SV=1) HSP 1 Score: 68.1662 bits (165), Expect = 1.011e-7 Identity = 49/149 (32.89%), Postives = 75/149 (50.34%), Query Frame = 1 Query: 4492 EPTTTRPH-VDKRI---VFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 EPT T H VD F + EIL E++ +EN + P+W + K Y +KG PP + D++ +V+ I+ L G K A KW +R++KD VD +L+ +L++EE +WI Y+ E VK Q+ + IF Sbjct: 321 EPTQTLSHAVDAPTGIFCFDLTGEILREMYQYENEVEPPAW--QKPVPKRQRY--YKGITPPTTVDVLLPVVQT---AAISILGLNGAVGKMRGKTAN------KWSVRKKKDHVDAVLVKELQEEEADWISYNHDETAVKLQLTDTIF 456
BLAST of Centrosomal protein 350 vs. TrEMBL
Match: A0A210PH66 (Centrosome-associated protein 350 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT04426 PE=4 SV=1) HSP 1 Score: 69.3218 bits (168), Expect = 1.186e-7 Identity = 46/169 (27.22%), Postives = 80/169 (47.34%), Query Frame = 1 Query: 4423 ELPDLYVDTEPITNE-EEIFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 E PD Y TE N+ + +FE +++F +I+ +I+ E+ +W + K ++G PP + D+++ IV++ V ++ D N +W +R++KD VD +L+ +LR+EE +W+ YDD E VK Q+ E IF Sbjct: 2844 EPPDTYYSTEDNNNDVDSKSRRVFE----------KLLFDSTGDIIRDIYKEEDQDTTCAWKQT----KRTRQKYYRGANPPTTIDVLKPIVQKAVIEILGLNGSRKVDKN-------------RWSVRKKKDHVDNILVEELREEEPDWVNYDDDETAVKMQLTEAIF 2985
BLAST of Centrosomal protein 350 vs. TrEMBL
Match: A0A3B3BYI6 (Centrosomal protein 350 OS=Oryzias melastigma OX=30732 PE=4 SV=1) HSP 1 Score: 67.781 bits (164), Expect = 3.001e-7 Identity = 63/227 (27.75%), Postives = 110/227 (48.46%), Query Frame = 1 Query: 4282 LKEKLSWLIPLNSENIEPLVESATRYLLEYK--KKHGFIADTAFSDEENELPDL-YVDTEPITNEEE-IFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSL-WKGDRPPESFDLVRRIVRERVDVLINQKNLFVTD---GNFGAKEAESQ----SKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 L E+ + ++P ++ + +V +ATR + E K G + D+ N P L Y+ E E+E + + + K+ VF + EIL +I+S + QP WV + ++IY + GD IN+ FVT FG K+ ++Q K++K+ R+++D VD++L+ +L++EE +W+ YD+ E VK Q+A+ IF Sbjct: 2656 LPEQPAMVVPHSATEVGKMVHAATREIWEACNLGKAGTLMDSQMP---NPKPSLEYLSEESHKQEQEAVSIRSY----------KQAVFDLTWEILQQIYSEDPVTDQPQWVKPRQVKSSSIYQVKTSGD--------------------INRIQEFVTTEVLKLFGLKQDQNQKTDWQKMLKFG-RKKRDRVDQILVQELQEEEAQWVNYDEDEFSVKMQLADSIF 2848
BLAST of Centrosomal protein 350 vs. TrEMBL
Match: R7V3Q2 (CAP-Gly domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_226518 PE=4 SV=1) HSP 1 Score: 67.3958 bits (163), Expect = 3.110e-7 Identity = 53/225 (23.56%), Postives = 102/225 (45.33%), Query Frame = 1 Query: 4261 LDINRDLLKEKLSWLIPLNSENIEPLVESATRYLLEYKKKHGFIADTAFSDEEN---ELPDLYVDTEPITNEEEIFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 LD+ + L E+L + +P E + PL+ + E ++++G D+ ++ D D E + + V KR+VF + E+L +++ E H + W + + PP + ++ ++ RV ++++ + AKE ++ W R++KD VD++L+ +LR EE +WI YDD E VK Q+++ +F Sbjct: 786 LDLRK--LNEELIYAVPNQKEQLVPLIHNTAEVFWE-RRRYGEAWDSTVQPPQDFFDAAEDQGADMESRSKK----------------VYKRMVFDLTAEVLRDLYKDEGHSEESFW----PQFRTQRAWPVRERTPPTTLQALKPVLESRVLKVLHRAD--------PAKEGAPSRRLKTWSSRKKKDHVDQILVQELRHEEPDWINYDDDELAVKMQLSDALF 979
BLAST of Centrosomal protein 350 vs. Ensembl Nematostella
Match: EDO47207 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMU3]) HSP 1 Score: 52.373 bits (124), Expect = 1.362e-7 Identity = 42/145 (28.97%), Postives = 67/145 (46.21%), Query Frame = 1 Query: 4492 EPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 +P +++VF + ++ +I E+ +P W+ K+ IY + P D ++V+ RV LI L N ++ K K KD VD +LI +LR+EE +W+ YDD E VKFQ+A+ I Sbjct: 2 DPNAASKQSYQKLVFDLTGDVFRDILHEESPPARPLWMKQRRRQKSRIY---RSLTPLRDEDDYLQVVQSRVMNLIG---LGTERPNLETLRRKTPLKAGK------KDAVDAILIQELREEEPQWVDYDDDELAVKFQVADAIL 134
BLAST of Centrosomal protein 350 vs. Ensembl Medaka
Match: cep350 (centrosomal protein 350 [Source:ZFIN;Acc:ZDB-GENE-030131-6975]) HSP 1 Score: 60.8474 bits (146), Expect = 1.739e-8 Identity = 54/217 (24.88%), Postives = 101/217 (46.54%), Query Frame = 1 Query: 4297 SWLIPLNSENIEPLVESATRYLLEYKKKHGFIADTAFSDEENELPDL---YVDTEPITNEEEIFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQ----SKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 + ++P + + +V +ATR + E G A D + +P Y+ E E+E + R + K+ VF + EI+ +I++ + QP WV ++IY V+ D + + L + FG K+ ++Q K++K+ R+++D VD++L+ +L++EE +W+ YD+ E VK Q+A+ IF Sbjct: 2230 AMVVPHSVSEVGKMVHAATREIWEA---CGLGKGGALLDSQTPIPTPSLEYLSDESCKQEQEAV-------SIRSY--KQAVFDLTWEIIQQIYAKDPVTDQPQWVKPRQFKSSSIYQ-----------------VKTSGDEFVTAEILKL----FGLKQDQNQKTDWQKMLKFG-RKKRDRVDQILVQELQEEEAQWVNYDEDELSVKMQLADSIF 2412
BLAST of Centrosomal protein 350 vs. Ensembl Medaka
Match: cep350 (centrosomal protein 350 [Source:ZFIN;Acc:ZDB-GENE-030131-6975]) HSP 1 Score: 53.9138 bits (128), Expect = 1.961e-6 Identity = 38/138 (27.54%), Postives = 71/138 (51.45%), Query Frame = 1 Query: 4525 RIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQ----SKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIF 4926 + VF + EI+ +I++ + QP WV ++IY V+ D + + L + FG K+ ++Q K++K+ R+++D VD++L+ +L++EE +W+ YD+ E VK Q+A+ IF Sbjct: 2262 QAVFDLTWEIIQQIYAKDPVTDQPQWVKPRQFKSSSIYQ-----------------VKTSGDEFVTAEILKL----FGLKQDQNQKTDWQKMLKFG-RKKRDRVDQILVQELQEEEAQWVNYDEDELSVKMQLADSIF 2377
BLAST of Centrosomal protein 350 vs. Planmine SMEST
Match: SMESG000033533.1 (SMESG000033533.1) HSP 1 Score: 2950.61 bits (7648), Expect = 0.000e+0 Identity = 1594/1625 (98.09%), Postives = 1599/1625 (98.40%), Query Frame = 1 Query: 55 MISKESEYLIQIAEEQLERLNKSLYLYQKNSEMESDIXXXXXXXXXXNNFKESSSMNVDINTNVLNLKTDLKPIYKIIKKQKDECSSGSSFKRKLKDNEKKKQHLTMPPPISNPDHIRDWRNGVNLVKKTLGSNNRISQKSPINKSQSTSPCSLKKKQRISTFWNDECNKRICKSPKKDISNSDKTLNNCCSRRTSDKEEIQRYIKNKQKAAREKRLETEMMAKARKENIKASLNNLENHHQNNFLQYLSSKQNYIKPSSEQDYVKSRSMSSLNKTKLVTPIYDELEREGFLEYFDVSNCDHHFISNLTSKYKNGLNSTVDSGIETGEWYRSLTPEKFRSSYERINEHNXXXXXXXXXXXXXXXXXDLRLDKSYKNSKLKTDHYNKLKQKYQEQISAYDASSENEFANENFDKNTASPEFSVVSDEIAKIPKSPLVRMKVDSNDNLDLLQVNLKISENFEKPNEITDRNDKRIIELYENLTKALLTAQIPSKFEDKESERDKLDKISQAVQNFIKTKESIEYSKASSCLSLHSAFNSYQNINDTNCKSKSKLVTITDSNYEKKNSRKVIPXXXXXXXXXXXXXXXXXKTAPNNNHGFPKESIELKIQKENVPEYLSINSEIITNYNVPEPININEYKETLQKREERANELINLTKNLRKESKRVIKLEKKAFEVSKRFIPNIKSDKKSTTDERNSTRVDSRNEESLKFSPISCLKMDPKSTENQQTLKMTYPQFHPSDNANESPQFVKDFQSQSSQSENDXXXXXXXXXXXXXXDQXXXXXXXXXXXXXXXKKKQLVSTLKRRQKEIKRDKIKQKEIVLQKQIDMYDNYLEKLQTTMDQLSSKIXXXXXXXXXXXHTLTGSNCNLTDLDCKKDHVDIQDDFHSSAHFVDNNKNESEMILTINAIPILSKENNETXXXXXXXXXXXXXXXXXXXXXXENNKHIQTNDLDNLSDMVGNYQEEVDNESLNEINKPQSDVENLINFSPPEECSQRNTGEMVYGDVEESNFPNFAKKDHLFDLFFNSNSGDCSTDANRNGNIVLEHDQVSSYLNDLLSKNVEDNESVHDDVLQQLYINANSSDPVETNTVLDALLSTNSLPNIPVTVPNSVNSWIPFSDLDALGSSESKNDQDEKKTPEMVKDIVEICIEEKENAKEYEFSNSSVSVKLVENLXXXXXXXXXXXIDENNFKLFIAKADTIKPVAILVENIYDEEENSGNRIQNAETISIDGSSISEVDSFNNFIEEDSLENANLCRISPKNSDESLYANKTIQPNATSLNIHAENIEESSNHLLKDDIFSFIPEQSLSSCRVDELVDILLNKLILTEIENIKPNLAETEQQKVNTYTPESVVEFQLAPFNDEETDNVPIIQEKGSFFDVLKSEDLWELGDLTIEDSNKVLTLDGPSTLDINRDLLKEKLSWLIPLNSENIEPLVESATRYLLEYKKKHGFIADTAFSDEENELPDLYVDTEPITNEEEIFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIFH 4929 MISKESEYLIQIAEEQLERLNKSLYLYQKNSEMESDILSSSLSLSCSNNFKESSSMNVDINTNVLNLKTDLKPIYKIIKKQKDECSSGSSFKRKLKDNEKKKQHLTMPPPISNPDHIRDWRNGVNLVKKTLGSNNRISQKSPINKSQSTSPCSLKKKQRISTFWNDECNKRICKSPKKDISNSDKTLNNCCSRRTSDKEEIQRYIKNKQKAAREKRLETEMMAKARKENIKASLNNLENHHQNNF+QYLSSKQNYIKPSSEQDYVKSRSMSSLNKTKLVTPIYDELEREGFLEYFDVSNCDHHFISNLTSKYKNGLNSTVDSGIETGEWYRSLTPEKFRSSYERINE+NSYLPPPLPPSSKPVSQSDLRLDKSYKNSKLKTDHYNKLKQKYQEQISAYDASSENEFANENFDKNTASPEFSVVSDEIAKIPKSPLVRMKVDSNDNLDLLQVNLKISENFEKPNEITDRNDKRIIELYENLT ALLTAQIPSKFEDKESERDKLDKISQAVQNFIKTKESIEYSKASSCLSLHSAFNSYQNINDTNCKSKSKLVTITDSNYEKKNSRKVIPTELEASEMELELATLSSKTAPNNNHGFPKESIELKIQKENVPEYLSINSEIITNYNVPEPININEYKETLQKREERANELINLTKNLRKESKRVIKLEKKAFEVSKRFIPNIKSDKKSTTDERNSTRVDSRNEESLKFSPISCLKMDPKSTENQQTLKMTYPQFHPSDNANESPQF KDFQSQSSQSENDEITISISEVTTTLTDQSELEARLLALRSEMEKKKQLVSTLKRRQKEIKRDKIKQKEIVLQKQIDMYDNYLEKLQTTMDQLSSKIDDDDGNNSDDSHTLTGSNCNLTDLDCKKDHVDIQDDFHSSAHFVDNNKNESEMILT N IPILSKENNETRDLNRDLILNLRSRSSSLDSLIENNKHIQTNDLDNLSDMVGNYQEEVDNESLNEINKPQSDVENLINFSPPEECSQRNTGEMVYGDVEESNFPNFAKKDHLFDLFFNSNSGDCSTDANRNGNIVLEHDQVSSYLNDLLSKNVEDNESVHDDVLQQLYINANSSDPVETNTVLDALLSTNSLPNIPVTVPNSVNSWIPFSDLDALGSSESKND DEKKTPEMVKDIVEICIEEKENAKE EFSNSSVSVKLVENLS ++NF DTIKPVAILVENIYDEEENSGNRIQNAETISIDGSSISEVDSFNNFIEEDSLENANLCRISPKNSDESLYANKTIQPNATSLNIHAENIEESSNHLLKDDIFSFIPEQSLSSCRVDELVDILLNKLILTEIENIKPNLAETEQQKVNTYTPESVVEFQLAPFNDE+TDNVPIIQEKGSFFDVLKSEDLWELGDLTIEDSNKVLTLDGPSTLDINRDLLKEKLSWLIPLNSENIEPLVESATRYLLEYKKKHGFIADTAFSDEENELPD YVDTEPITNEEEIFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIFH Sbjct: 1 MISKESEYLIQIAEEQLERLNKSLYLYQKNSEMESDILSSSLSLSCSNNFKESSSMNVDINTNVLNLKTDLKPIYKIIKKQKDECSSGSSFKRKLKDNEKKKQHLTMPPPISNPDHIRDWRNGVNLVKKTLGSNNRISQKSPINKSQSTSPCSLKKKQRISTFWNDECNKRICKSPKKDISNSDKTLNNCCSRRTSDKEEIQRYIKNKQKAAREKRLETEMMAKARKENIKASLNNLENHHQNNFMQYLSSKQNYIKPSSEQDYVKSRSMSSLNKTKLVTPIYDELEREGFLEYFDVSNCDHHFISNLTSKYKNGLNSTVDSGIETGEWYRSLTPEKFRSSYERINEYNSYLPPPLPPSSKPVSQSDLRLDKSYKNSKLKTDHYNKLKQKYQEQISAYDASSENEFANENFDKNTASPEFSVVSDEIAKIPKSPLVRMKVDSNDNLDLLQVNLKISENFEKPNEITDRNDKRIIELYENLTNALLTAQIPSKFEDKESERDKLDKISQAVQNFIKTKESIEYSKASSCLSLHSAFNSYQNINDTNCKSKSKLVTITDSNYEKKNSRKVIPTELEASEMELELATLSSKTAPNNNHGFPKESIELKIQKENVPEYLSINSEIITNYNVPEPININEYKETLQKREERANELINLTKNLRKESKRVIKLEKKAFEVSKRFIPNIKSDKKSTTDERNSTRVDSRNEESLKFSPISCLKMDPKSTENQQTLKMTYPQFHPSDNANESPQFGKDFQSQSSQSENDEITISISEVTTTLTDQSELEARLLALRSEMEKKKQLVSTLKRRQKEIKRDKIKQKEIVLQKQIDMYDNYLEKLQTTMDQLSSKIDDDDGNNSDDSHTLTGSNCNLTDLDCKKDHVDIQDDFHSSAHFVDNNKNESEMILTTNVIPILSKENNETRDLNRDLILNLRSRSSSLDSLIENNKHIQTNDLDNLSDMVGNYQEEVDNESLNEINKPQSDVENLINFSPPEECSQRNTGEMVYGDVEESNFPNFAKKDHLFDLFFNSNSGDCSTDANRNGNIVLEHDQVSSYLNDLLSKNVEDNESVHDDVLQQLYINANSSDPVETNTVLDALLSTNSLPNIPVTVPNSVNSWIPFSDLDALGSSESKNDHDEKKTPEMVKDIVEICIEEKENAKEDEFSNSSVSVKLVENLS------------DSNF------TDTIKPVAILVENIYDEEENSGNRIQNAETISIDGSSISEVDSFNNFIEEDSLENANLCRISPKNSDESLYANKTIQPNATSLNIHAENIEESSNHLLKDDIFSFIPEQSLSSCRVDELVDILLNKLILTEIENIKPNLAETEQQKVNTYTPESVVEFQLAPFNDEDTDNVPIIQEKGSFFDVLKSEDLWELGDLTIEDSNKVLTLDGPSTLDINRDLLKEKLSWLIPLNSENIEPLVESATRYLLEYKKKHGFIADTAFSDEENELPDWYVDTEPITNEEEIFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIFH 1607
BLAST of Centrosomal protein 350 vs. Planmine SMEST
Match: SMESG000033533.1 (SMESG000033533.1) HSP 1 Score: 2929.43 bits (7593), Expect = 0.000e+0 Identity = 1576/1625 (96.98%), Postives = 1582/1625 (97.35%), Query Frame = 1 Query: 55 MISKESEYLIQIAEEQLERLNKSLYLYQKNSEMESDIXXXXXXXXXXNNFKESSSMNVDINTNVLNLKTDLKPIYKIIKKQKDECSSGSSFKRKLKDNEKKKQHLTMPPPISNPDHIRDWRNGVNLVKKTLGSNNRISQKSPINKSQSTSPCSLKKKQRISTFWNDECNKRICKSPKKDISNSDKTLNNCCSRRTSDKEEIQRYIKNKQKAAREKRLETEMMAKARKENIKASLNNLENHHQNNFLQYLSSKQNYIKPSSEQDYVKSRSMSSLNKTKLVTPIYDELEREGFLEYFDVSNCDHHFISNLTSKYKNGLNSTVDSGIETGEWYRSLTPEKFRSSYERINEHNXXXXXXXXXXXXXXXXXDLRLDKSYKNSKLKTDHYNKLKQKYQEQISAYDASSENEFANENFDKNTASPEFSVVSDEIAKIPKSPLVRMKVDSNDNLDLLQVNLKISENFEKPNEITDRNDKRIIELYENLTKALLTAQIPSKFEDKESERDKLDKISQAVQNFIKTKESIEYSKASSCLSLHSAFNSYQNINDTNCKSKSKLVTITDSNYEKKNSRKVIPXXXXXXXXXXXXXXXXXKTAPNNNHGFPKESIELKIQKENVPEYLSINSEIITNYNVPEPININEYKETLQKREERANELINLTKNLRKESKRVIKLEKKAFEVSKRFIPNIKSDKKSTTDERNSTRVDSRNEESLKFSPISCLKMDPKSTENQQTLKMTYPQFHPSDNANESPQFVKDFQSQSSQSENDXXXXXXXXXXXXXXDQXXXXXXXXXXXXXXXKKKQLVSTLKRRQKEIKRDKIKQKEIVLQKQIDMYDNYLEKLQTTMDQLSSKIXXXXXXXXXXXHTLTGSNCNLTDLDCKKDHVDIQDDFHSSAHFVDNNKNESEMILTINAIPILSKENNETXXXXXXXXXXXXXXXXXXXXXXENNKHIQTNDLDNLSDMVGNYQEEVDNESLNEINKPQSDVENLINFSPPEECSQRNTGEMVYGDVEESNFPNFAKKDHLFDLFFNSNSGDCSTDANRNGNIVLEHDQVSSYLNDLLSKNVEDNESVHDDVLQQLYINANSSDPVETNTVLDALLSTNSLPNIPVTVPNSVNSWIPFSDLDALGSSESKNDQDEKKTPEMVKDIVEICIEEKENAKEYEFSNSSVSVKLVENLXXXXXXXXXXXIDENNFKLFIAKADTIKPVAILVENIYDEEENSGNRIQNAETISIDGSSISEVDSFNNFIEEDSLENANLCRISPKNSDESLYANKTIQPNATSLNIHAENIEESSNHLLKDDIFSFIPEQSLSSCRVDELVDILLNKLILTEIENIKPNLAETEQQKVNTYTPESVVEFQLAPFNDEETDNVPIIQEKGSFFDVLKSEDLWELGDLTIEDSNKVLTLDGPSTLDINRDLLKEKLSWLIPLNSENIEPLVESATRYLLEYKKKHGFIADTAFSDEENELPDLYVDTEPITNEEEIFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIFH 4929 MISKESEYLIQIAEEQLERLNKSLYLYQKNSEME +SSSMNVDINTNVLNLKTDLKPIYKIIKKQKDECSSGSSFKRKLKDNEKKKQHLTMPPPISNPDHIRDWRNGVNLVKKTLGSNNRISQKSPINKSQSTSPCSLKKKQRISTFWNDECNKRICKSPKKDISNSDKTLNNCCSRRTSDKEEIQRYIKNKQKAAREKRLETEMMAKARKENIKASLNNLENHHQNNF+QYLSSKQNYIKPSSEQDYVKSRSMSSLNKTKLVTPIYDELEREGFLEYFDVSNCDHHFISNLTSKYKNGLNSTVDSGIETGEWYRSLTPEKFRSSYERINE+NSYLPPPLPPSSKPVSQSDLRLDKSYKNSKLKTDHYNKLKQKYQEQISAYDASSENEFANENFDKNTASPEFSVVSDEIAKIPKSPLVRMKVDSNDNLDLLQVNLKISENFEKPNEITDRNDKRIIELYENLT ALLTAQIPSKFEDKESERDKLDKISQAVQNFIKTKESIEYSKASSCLSLHSAFNSYQNINDTNCKSKSKLVTITDSNYEKKNSRKVIPTELEASEMELELATLSSKTAPNNNHGFPKESIELKIQKENVPEYLSINSEIITNYNVPEPININEYKETLQKREERANELINLTKNLRKESKRVIKLEKKAFEVSKRFIPNIKSDKKSTTDERNSTRVDSRNEESLKFSPISCLKMDPKSTENQQTLKMTYPQFHPSDNANESPQF KDFQSQSSQSENDEITISISEVTTTLTDQSELEARLLALRSEMEKKKQLVSTLKRRQKEIKRDKIKQKEIVLQKQIDMYDNYLEKLQTTMDQLSSKIDDDDGNNSDDSHTLTGSNCNLTDLDCKKDHVDIQDDFHSSAHFVDNNKNESEMILT N IPILSKENNETRDLNRDLILNLRSRSSSLDSLIENNKHIQTNDLDNLSDMVGNYQEEVDNESLNEINKPQSDVENLINFSPPEECSQRNTGEMVYGDVEESNFPNFAKKDHLFDLFFNSNSGDCSTDANRNGNIVLEHDQVSSYLNDLLSKNVEDNESVHDDVLQQLYINANSSDPVETNTVLDALLSTNSLPNIPVTVPNSVNSWIPFSDLDALGSSESKND DEKKTPEMVKDIVEICIEEKENAKE EFSNSSVSVKLVENLS ++NF DTIKPVAILVENIYDEEENSGNRIQNAETISIDGSSISEVDSFNNFIEEDSLENANLCRISPKNSDESLYANKTIQPNATSLNIHAENIEESSNHLLKDDIFSFIPEQSLSSCRVDELVDILLNKLILTEIENIKPNLAETEQQKVNTYTPESVVEFQLAPFNDE+TDNVPIIQEKGSFFDVLKSEDLWELGDLTIEDSNKVLTLDGPSTLDINRDLLKEKLSWLIPLNSENIEPLVESATRYLLEYKKKHGFIADTAFSDEENELPD YVDTEPITNEEEIFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIFH Sbjct: 1 MISKESEYLIQIAEEQLERLNKSLYLYQKNSEME-----------------KSSSMNVDINTNVLNLKTDLKPIYKIIKKQKDECSSGSSFKRKLKDNEKKKQHLTMPPPISNPDHIRDWRNGVNLVKKTLGSNNRISQKSPINKSQSTSPCSLKKKQRISTFWNDECNKRICKSPKKDISNSDKTLNNCCSRRTSDKEEIQRYIKNKQKAAREKRLETEMMAKARKENIKASLNNLENHHQNNFMQYLSSKQNYIKPSSEQDYVKSRSMSSLNKTKLVTPIYDELEREGFLEYFDVSNCDHHFISNLTSKYKNGLNSTVDSGIETGEWYRSLTPEKFRSSYERINEYNSYLPPPLPPSSKPVSQSDLRLDKSYKNSKLKTDHYNKLKQKYQEQISAYDASSENEFANENFDKNTASPEFSVVSDEIAKIPKSPLVRMKVDSNDNLDLLQVNLKISENFEKPNEITDRNDKRIIELYENLTNALLTAQIPSKFEDKESERDKLDKISQAVQNFIKTKESIEYSKASSCLSLHSAFNSYQNINDTNCKSKSKLVTITDSNYEKKNSRKVIPTELEASEMELELATLSSKTAPNNNHGFPKESIELKIQKENVPEYLSINSEIITNYNVPEPININEYKETLQKREERANELINLTKNLRKESKRVIKLEKKAFEVSKRFIPNIKSDKKSTTDERNSTRVDSRNEESLKFSPISCLKMDPKSTENQQTLKMTYPQFHPSDNANESPQFGKDFQSQSSQSENDEITISISEVTTTLTDQSELEARLLALRSEMEKKKQLVSTLKRRQKEIKRDKIKQKEIVLQKQIDMYDNYLEKLQTTMDQLSSKIDDDDGNNSDDSHTLTGSNCNLTDLDCKKDHVDIQDDFHSSAHFVDNNKNESEMILTTNVIPILSKENNETRDLNRDLILNLRSRSSSLDSLIENNKHIQTNDLDNLSDMVGNYQEEVDNESLNEINKPQSDVENLINFSPPEECSQRNTGEMVYGDVEESNFPNFAKKDHLFDLFFNSNSGDCSTDANRNGNIVLEHDQVSSYLNDLLSKNVEDNESVHDDVLQQLYINANSSDPVETNTVLDALLSTNSLPNIPVTVPNSVNSWIPFSDLDALGSSESKNDHDEKKTPEMVKDIVEICIEEKENAKEDEFSNSSVSVKLVENLS------------DSNF------TDTIKPVAILVENIYDEEENSGNRIQNAETISIDGSSISEVDSFNNFIEEDSLENANLCRISPKNSDESLYANKTIQPNATSLNIHAENIEESSNHLLKDDIFSFIPEQSLSSCRVDELVDILLNKLILTEIENIKPNLAETEQQKVNTYTPESVVEFQLAPFNDEDTDNVPIIQEKGSFFDVLKSEDLWELGDLTIEDSNKVLTLDGPSTLDINRDLLKEKLSWLIPLNSENIEPLVESATRYLLEYKKKHGFIADTAFSDEENELPDWYVDTEPITNEEEIFVTLFEPTTTRPHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSSAMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGAKEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEIFH 1590
BLAST of Centrosomal protein 350 vs. Planmine SMEST
Match: SMESG000026378.1 (SMESG000026378.1) HSP 1 Score: 75.8702 bits (185), Expect = 2.927e-13 Identity = 64/230 (27.83%), Postives = 109/230 (47.39%), Query Frame = 1 Query: 4264 DINRDLLKEKLSWLIPLNSENIEPLVESATRYLLEYKKKHGFIADTAFSDEENELPDLYVDTEPITNEEEIFVT--LFEPTTTR------PHVDKRIVFHIVLEILLEIFSFENHLCQPSWVHSS-AMLKNNIYSLWKGDRPPESFDLVRRIVRERVDVLINQKNLFVTDGNFGA-KEAESQSKIIKWCIRQQKDDVDKLLINDLRKEENEWIYYDDAEEEVKFQIAEEI 4923 D+ DLL + LIP ENI PL++ A L ++ AF+ +P +++ + I+ T + E +R P++ K VFH+VLEI+ I+ ++ L W+ + + KN LW+G P S +L+R+IV K L + GA ++ ++++ +W +Q D VD+LLI++ E+ W YD A E F + ++I Sbjct: 1441 DVQYDLLDD----LIPWVDENILPLIDVAIEQLFHARQNRTGTLSEAFAHCCKNIPSRFIEKNSSAEKINIYHTWQVNESLASRNLQVKQPYIPKIAVFHLVLEIMERIYELDDQLDPVPWMEDAFNIFKNRKLILWEGTEAPNSIELLRKIV---------TKQLMSVNILSGAPSKSTNRTRQHRWFHKQTDDIVDRLLIDETLHEDILWQNYDAALETTIFALIDDI 1657 The following BLAST results are available for this feature:
BLAST of Centrosomal protein 350 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 3
BLAST of Centrosomal protein 350 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Centrosomal protein 350 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Centrosomal protein 350 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of Centrosomal protein 350 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of Centrosomal protein 350 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 1
BLAST of Centrosomal protein 350 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 0
BLAST of Centrosomal protein 350 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Centrosomal protein 350 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of Centrosomal protein 350 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Centrosomal protein 350 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Centrosomal protein 350 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Centrosomal protein 350 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of Centrosomal protein 350 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30022622 ID=SMED30022622|Name=Centrosomal protein 350|organism=Schmidtea mediterranea sexual|type=transcript|length=5055bpback to top protein sequence of SMED30022622-orf-1 >SMED30022622-orf-1 ID=SMED30022622-orf-1|Name=SMED30022622-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1643bp MISKESEYLIQIAEEQLERLNKSLYLYQKNSEMESDILSSSLSLSCSNNFback to top Annotated Terms
The following terms have been associated with this transcript:
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