SMED30022562

Overview


Name	SMED30022562
Smed ID	SMED30022562
Length (bp)	1283

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SMED30022562 (SMED30022562) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30022562 (SMED30022562) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30022562 (SMED30022562) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30022562 (SMED30022562) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30022562

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
epidermis	SMED30022562	SMESG000005008.1 SMESG000005007.1	dd_Smed_v4_5649_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30022562	SMESG000005008.1 SMESG000005007.1	dd_Smed_v4_5649_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30022562	SMESG000005008.1 SMESG000005007.1	dd_Smed_v4_5649_1_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Alignments

SMED30022562 aligns in the following genomic locations:


Alignment Location	Alignment Score
v31.000357:20..22608 -	6236

Homology

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BLAST of SMED30022562 vs. Ensembl Human
Match: RNF123 (ring finger protein 123 [Source:HGNC Symbol;Acc:HGNC:21148])

HSP 1 Score: 241.506 bits (615), Expect = 5.482e-72
Identity = 125/379 (32.98%), Postives = 209/379 (55.15%), Query Frame = -2

Query:   29 EKITKHVDQ---ADIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1147
            + + +H+DQ    D +  E++    GRLGP TV  +         +  D  + V+G S+F ++R+  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ GY+P+Q     +LV+AQ L+G    ++ + +D +             E    +      ++  Q    L  +++ +H   L+   ++ E+ L+  LL   +       QS V  +LD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L +AI++H+K++ ++L + L+
Sbjct:   62 QNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPV-------------EGRLLDKESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKFLLSNVLF 427

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BLAST of SMED30022562 vs. Ensembl Human
Match: RNF123 (ring finger protein 123 [Source:HGNC Symbol;Acc:HGNC:21148])

HSP 1 Score: 241.121 bits (614), Expect = 8.232e-70
Identity = 125/379 (32.98%), Postives = 209/379 (55.15%), Query Frame = -2

Query:   29 EKITKHVDQ---ADIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1147
            + + +H+DQ    D +  E++    GRLGP TV  +         +  D  + V+G S+F ++R+  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ GY+P+Q     +LV+AQ L+G    ++ + +D +             E    +      ++  Q    L  +++ +H   L+   ++ E+ L+  LL   +       QS V  +LD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L +AI++H+K++ ++L + L+
Sbjct:   62 QNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPV-------------EGRLLDKESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKFLLSNVLF 427

[Close]

BLAST of SMED30022562 vs. Ensembl Human
Match: RNF123 (ring finger protein 123 [Source:HGNC Symbol;Acc:HGNC:21148])

HSP 1 Score: 199.134 bits (505), Expect = 4.621e-56
Identity = 96/294 (32.65%), Postives = 162/294 (55.10%), Query Frame = -2

Query:   29 MQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 910
            MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ GY+P+Q     +LV+AQ L+G    ++ + +D +             E    +      ++  Q    L  +++ +H   L+   ++ E+ L+  LL   +       QS V  +LD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L +AI++H+K++ ++L + L+
Sbjct:    1 MQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPV-------------EGRLLDKESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKFLLSNVLF 281

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BLAST of SMED30022562 vs. Ensembl Human
Match: RSPRY1 (ring finger and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29420])

HSP 1 Score: 83.1889 bits (204), Expect = 1.608e-16
Identity = 54/145 (37.24%), Postives = 71/145 (48.97%), Query Frame = -2

Query:  578 SDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFT--EENGVGDTPDSYGYDGNRIKLW-NVLSKKY-GEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIV--YYPAVSLSQGDSITLNFGGSMFLYP 994
            S F SVR   CV  G W+YEV + + GVMQ+GW T   KF   E  G+GD   S  YDG R  +W N  SK +    W  GD +   +DL E ++ +F NG  L     + +V  + V  ++ A S         NFG   F YP
Sbjct:  345 SSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQL---PPEKQVFSSTVSGFFAAASFMSYQQCEFNFGAKPFKYP 486

[Close]

Query:  578 SDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFT--EENGVGDTPDSYGYDGNRIKLW-NVLSKKY-GEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIV--YYPAVSLSQGDSITLNFGGSMFLYP 994
            S F SVR   CV  G W+YEV + + GVMQ+GW T   KF   E  G+GD   S  YDG R  +W N  SK +    W  GD +   +DL E ++ +F NG  L     + +V  + V  ++ A S         NFG   F YP
Sbjct:  345 SSFESVRCTFCVDAGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHIHPCWKEGDTVGFLLDLNEKQMIFFLNGNQL---PPEKQVFSSTVSGFFAAASFMSYQQCEFNFGAKPFKYP 486

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BLAST of SMED30022562 vs. Ensembl Celegans
Match: F16A11.1 (pep chromosome:WBcel235:I:9393953:9404024:-1 gene:WBGene00008876.1 transcript:F16A11.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F16A11.1)

HSP 1 Score: 77.0258 bits (188), Expect = 7.549e-15
Identity = 60/195 (30.77%), Postives = 91/195 (46.67%), Query Frame = -2

Query:  581 DIKVVETKPLQFGRLGPETVSFNKM-----CQGHIKI--DSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKF--TEENGVGDTPDSYGYDGNRIKLW-NVLSKKY-GEAWDIGDVITCCIDLTEAKLEYFRNGKSLG-----IISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLY 1117
            +I ++E++P  +     ET   N M        ++KI  D       +S F SVR    V +G W+YE  + + GVMQ+G  T+  +F   E  G+GD   S  YDG R  +W N  S K+  E W  GDVI   +++ E ++ ++ NG  L       +S++    P+   + A S         NFG S F Y
Sbjct:  333 NIFILESRPYSYETC--ETSKINAMLNHEDVSEYLKIGPDGLEARCDVSSFESVRCTFEVMDGVWYYEATVLTSGVMQIGLATKRSRFLNHEGYGIGDDASSVAYDGCRQLVWYNAKSHKHEHENWQPGDVIGVLLNIPEGEVVFYLNGTPLKEPETEFLSNR---QPSEGVFAAASFMSFQQCRFNFGASRFKY 522

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BLAST of SMED30022562 vs. Ensembl Celegans
Match: F16A11.1 (pep chromosome:WBcel235:I:9393948:9398399:-1 gene:WBGene00008876.1 transcript:F16A11.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F16A11.1)

HSP 1 Score: 76.6406 bits (187), Expect = 7.937e-15
Identity = 60/195 (30.77%), Postives = 91/195 (46.67%), Query Frame = -2

Query:  581 DIKVVETKPLQFGRLGPETVSFNKM-----CQGHIKI--DSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKF--TEENGVGDTPDSYGYDGNRIKLW-NVLSKKY-GEAWDIGDVITCCIDLTEAKLEYFRNGKSLG-----IISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLY 1117
            +I ++E++P  +     ET   N M        ++KI  D       +S F SVR    V +G W+YE  + + GVMQ+G  T+  +F   E  G+GD   S  YDG R  +W N  S K+  E W  GDVI   +++ E ++ ++ NG  L       +S++    P+   + A S         NFG S F Y
Sbjct:  281 NIFILESRPYSYETC--ETSKINAMLNHEDVSEYLKIGPDGLEARCDVSSFESVRCTFEVMDGVWYYEATVLTSGVMQIGLATKRSRFLNHEGYGIGDDASSVAYDGCRQLVWYNAKSHKHEHENWQPGDVIGVLLNIPEGEVVFYLNGTPLKEPETEFLSNR---QPSEGVFAAASFMSFQQCRFNFGASRFKY 470

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BLAST of SMED30022562 vs. Ensembl Celegans
Match: unc-68 (pep chromosome:WBcel235:V:6901697:6924961:-1 gene:WBGene00006801.1 transcript:K11C4.5k.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-68)

HSP 1 Score: 73.559 bits (179), Expect = 1.277e-13
Identity = 42/133 (31.58%), Postives = 66/133 (49.62%), Query Frame = -2

Query:  599 VRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSL------GIISDKIRVGPNIVYYPAVSLSQGDSITLNFG 979
              A   V  GKW++E  + + G M++GW       T E  +G    SY +DG   + W+  ++ YG+ W IGDV+ C +DL +  + +  NG+ L       +  D +  G  +V  PA++L  G    LNFG
Sbjct: 1080 AEATYAVCGGKWYFEFEILTAGYMKIGWMD--IGSTPEIQLGADDRSYAFDGYLGRKWHQGAETYGKEWKIGDVVGCFLDLNDRTISFSLNGELLLDPSGSEMAFDNVVCGDGLV--PAMTLGSGQRGRLNFG 1208

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BLAST of SMED30022562 vs. Ensembl Celegans
Match: unc-68 (pep chromosome:WBcel235:V:6901697:6929038:-1 gene:WBGene00006801.1 transcript:K11C4.5c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-68)

HSP 1 Score: 73.559 bits (179), Expect = 1.312e-13
Identity = 42/133 (31.58%), Postives = 66/133 (49.62%), Query Frame = -2

Query:  599 VRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSL------GIISDKIRVGPNIVYYPAVSLSQGDSITLNFG 979
              A   V  GKW++E  + + G M++GW       T E  +G    SY +DG   + W+  ++ YG+ W IGDV+ C +DL +  + +  NG+ L       +  D +  G  +V  PA++L  G    LNFG
Sbjct: 1082 AEATYAVCGGKWYFEFEILTAGYMKIGWMD--IGSTPEIQLGADDRSYAFDGYLGRKWHQGAETYGKEWKIGDVVGCFLDLNDRTISFSLNGELLLDPSGSEMAFDNVVCGDGLV--PAMTLGSGQRGRLNFG 1210

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BLAST of SMED30022562 vs. Ensembl Celegans
Match: unc-68 (pep chromosome:WBcel235:V:6901697:6924961:-1 gene:WBGene00006801.1 transcript:K11C4.5o.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-68)

HSP 1 Score: 73.559 bits (179), Expect = 1.323e-13
Identity = 42/133 (31.58%), Postives = 66/133 (49.62%), Query Frame = -2

Query:  599 VRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSL------GIISDKIRVGPNIVYYPAVSLSQGDSITLNFG 979
              A   V  GKW++E  + + G M++GW       T E  +G    SY +DG   + W+  ++ YG+ W IGDV+ C +DL +  + +  NG+ L       +  D +  G  +V  PA++L  G    LNFG
Sbjct: 1080 AEATYAVCGGKWYFEFEILTAGYMKIGWMD--IGSTPEIQLGADDRSYAFDGYLGRKWHQGAETYGKEWKIGDVVGCFLDLNDRTISFSLNGELLLDPSGSEMAFDNVVCGDGLV--PAMTLGSGQRGRLNFG 1208

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BLAST of SMED30022562 vs. Ensembl Fly
Match: CG6752 (gene:FBgn0038296 transcript:FBtr0306246)

HSP 1 Score: 216.468 bits (550), Expect = 1.377e-61
Identity = 112/354 (31.64%), Postives = 200/354 (56.50%), Query Frame = -2

Query:   29 GRLGPETVSFNKMCQGHIKIDS-QMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLI-ASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQ-SHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1081
             R+GP+   F+      +++ S ++ +     F++VRANCCVY G+W YE+ L +KGVMQ+GW +  C+F E +GVGDT  SYGYDG++ ++W++ +KKYG+ W IGDVI   ID+ +  +EY+RNG+S+G+  +K+  GP I ++ A+SL     I  NFG   F+YP+ G++P+  + I  L +A  L+ YL       V+   I S  ++Q         +      ++ST+   + I A+ L+    N + + +I E  L+  +    + ++ K N  S +  +L + WN +E + I  ++  L++ ++  +  T    +++   + L ++  +  H++T+ Y+LE  L+
Sbjct:   88 SRIGPDLTIFDVDYTTTVRVSSDRLALRSQGSFNTVRANCCVYGGRWMYEIHLHTKGVMQIGWASNSCQFNENSGVGDTKSSYGYDGSKQQIWHISTKKYGDKWQIGDVIGVTIDVDKEVIEYYRNGRSMGVAFNKLEKGPGISFFAAISLGYTQGIEANFGNRPFMYPVSGFQPLMARPILKLQRANLLMNYL-------VNLAGIFSKYNAQSGMAPTNGADA-----RVSTKKTVYCIFATLLIEKFTNEIFDPYIIEDVLLRKISSMTNLASEKENSYSVLHGLLSLFWNYMEGDEIKFVLRKLVNALLGTFTHTIQGLDYEKHRQALGMLHCLCLHEQTRKYLLEGKLF 429

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BLAST of SMED30022562 vs. Ensembl Fly
Match: CG6752 (gene:FBgn0038296 transcript:FBtr0083029)

HSP 1 Score: 216.468 bits (550), Expect = 1.377e-61
Identity = 112/354 (31.64%), Postives = 200/354 (56.50%), Query Frame = -2

Query:   29 GRLGPETVSFNKMCQGHIKIDS-QMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLI-ASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQ-SHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1081
             R+GP+   F+      +++ S ++ +     F++VRANCCVY G+W YE+ L +KGVMQ+GW +  C+F E +GVGDT  SYGYDG++ ++W++ +KKYG+ W IGDVI   ID+ +  +EY+RNG+S+G+  +K+  GP I ++ A+SL     I  NFG   F+YP+ G++P+  + I  L +A  L+ YL       V+   I S  ++Q         +      ++ST+   + I A+ L+    N + + +I E  L+  +    + ++ K N  S +  +L + WN +E + I  ++  L++ ++  +  T    +++   + L ++  +  H++T+ Y+LE  L+
Sbjct:   88 SRIGPDLTIFDVDYTTTVRVSSDRLALRSQGSFNTVRANCCVYGGRWMYEIHLHTKGVMQIGWASNSCQFNENSGVGDTKSSYGYDGSKQQIWHISTKKYGDKWQIGDVIGVTIDVDKEVIEYYRNGRSMGVAFNKLEKGPGISFFAAISLGYTQGIEANFGNRPFMYPVSGFQPLMARPILKLQRANLLMNYL-------VNLAGIFSKYNAQSGMAPTNGADA-----RVSTKKTVYCIFATLLIEKFTNEIFDPYIIEDVLLRKISSMTNLASEKENSYSVLHGLLSLFWNYMEGDEIKFVLRKLVNALLGTFTHTIQGLDYEKHRQALGMLHCLCLHEQTRKYLLEGKLF 429

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BLAST of SMED30022562 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0088640)

HSP 1 Score: 63.1586 bits (152), Expect = 3.817e-10
Identity = 50/200 (25.00%), Postives = 86/200 (43.00%), Query Frame = -2

Query:  431 VRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLS-KKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSL-----GIISDKIRVGPNIVYYPAVSLSQGDSITLNFG---GSMFLYPI----DGYKP----IQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFK 979
            V  N  V +GKW++E  + + G M++GW    C      G  DT  S+ +DG+ +   +  S + +G  ++ GDVI C ID+ E  + +  NG+ L     G  +        + + PA +L  G    L +G    S+  +      +GY+P    ++        K Q +    E +    +D  +I   AD+    K
Sbjct: 1083 VERNYAVTSGKWYFEFEVLTSGPMRVGWARADCYPGAMLGSEDT--SWAFDGHNVTKMHAGSIEHFGVRYEAGDVIGCFIDVKEQTISFSLNGELLMDALGGETTFADVTAEGVGFVPACTLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENTEEMPDCRIDVTRIPGGADTPPHLK 1280

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BLAST of SMED30022562 vs. Ensembl Fly
Match: ash2 (gene:FBgn0000139 transcript:FBtr0084659)

HSP 1 Score: 61.6178 bits (148), Expect = 4.399e-10
Identity = 51/221 (23.08%), Postives = 85/221 (38.46%), Query Frame = -2

Query:  515 DSQMTVLGLSDFSSVRANCCVYNGKWFYEV---RLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYD---GNRIKLWNVLSKKYGEAWDIGDVITCCIDLTE-------------------------------------------AKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYP---IDGYKPIQHQNIQNLVKAQCL 1021
            + ++ V G   +  VRA   V  G W++EV    +      +LGW  EY       G     D +GY        K      K Y +A+  GD +   I+L E                                           +++E+F+NG+S G+  + I  G    Y+PA+S+ +  ++++NF G  F YP   ++      H  ++ L+  QCL
Sbjct:  118 EDRLAVTGERGYCMVRATHSVNRGCWYFEVTIEEMPDGAATRLGWGREYGNLQAPLGY----DKFGYSWRSRKGTKFTESHGKHYSDAYVEGDTLGFLIELPEEASLDYLPNTFKDRPLVKFKSHLYYEDKDKITETLKNLHILQGSRIEFFKNGQSQGVAFEDIYAG---SYFPAISIHKSATVSVNF-GPAFKYPEVLVEHKAKGMHDRVEELITEQCL 330

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BLAST of SMED30022562 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0088638)

HSP 1 Score: 62.7734 bits (151), Expect = 4.581e-10
Identity = 50/200 (25.00%), Postives = 86/200 (43.00%), Query Frame = -2

Query:  431 VRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLS-KKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSL-----GIISDKIRVGPNIVYYPAVSLSQGDSITLNFG---GSMFLYPI----DGYKP----IQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFK 979
            V  N  V +GKW++E  + + G M++GW    C      G  DT  S+ +DG+ +   +  S + +G  ++ GDVI C ID+ E  + +  NG+ L     G  +        + + PA +L  G    L +G    S+  +      +GY+P    ++        K Q +    E +    +D  +I   AD+    K
Sbjct: 1083 VERNYAVTSGKWYFEFEVLTSGPMRVGWARADCYPGAMLGSEDT--SWAFDGHNVTKMHAGSIEHFGVRYEAGDVIGCFIDVKEQTISFSLNGELLMDALGGETTFADVTAEGVGFVPACTLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENTEEMPDCRIDVTRIPGGADTPPHLK 1280

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BLAST of SMED30022562 vs. Ensembl Zebrafish
Match: rnf123 (ring finger protein 123 [Source:ZFIN;Acc:ZDB-GENE-050208-529])

HSP 1 Score: 243.817 bits (621), Expect = 7.070e-71
Identity = 130/399 (32.58%), Postives = 213/399 (53.38%), Query Frame = -2

Query:   44 LAHVFPEMMNNKHSLSVTNIDIFLKEKITKHVDQ---ADIKVVETKPLQFGRLGPETVSFNKMC--QGHIKIDSQM-TVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYIL 1222
            L HVFP       + +     + L++ +  H+++    D    + +    G LGP TV  +     +G + +D  +  V+G S+FSS+RA  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDTPDSY YDGNR++ WNV +  YG++W  GD+++C IDL E  + +  NG+SLG+    I+ GP + Y+PA+SLS  +S+  NFG     YP   Y P+Q     +L+KA  L+GYL+ ++  ++D              +E    E      Q+       +  +++ NH   L+   ++ E  L+  LL   +          +  ++D+ W L+E   +   +  L+  ++  Y+ +P+ P+   Q  YL L  AI++H+K++ Y+L
Sbjct:   38 LHHVFPASSKQGPASAAYRKTLTLQD-LGAHLEKLLAEDNATEDGRDQTEGSLGPSTVVLDHSSGFEGLLFVDDDLLGVIGHSNFSSIRATTCVYKGKWVYEVLISSQGLMQIGWCTLNCRFNQEEGVGDTPDSYAYDGNRVRKWNVTTTNYGKSWAAGDIVSCLIDLDEGTITFCLNGQSLGVAFSNIKTGPGVAYFPAISLSFKESVAFNFGSRPLRYPY-CYLPLQSPPTADLIKAHRLLGYLKTVLSTSID-------------MQEEKIVEKDSSVWQLHGDPTILVTLAHIFNHFAPLMCKVYLVEDVLMNFLLSILEGGGSVDEHPLIQQLMDLFWLLMEDYEVRECLKQLMMSLLRAYRFSPIIPDLGFQIHYLRLTSAILRHEKSRKYLL 421

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BLAST of SMED30022562 vs. Ensembl Zebrafish
Match: rspry1 (ring finger and SPRY domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-061026-2])

HSP 1 Score: 83.1889 bits (204), Expect = 1.107e-16
Identity = 50/143 (34.97%), Postives = 71/143 (49.65%), Query Frame = -2

Query:  578 SDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFT--EENGVGDTPDSYGYDGNRIKLW-NVLSKKYGEA-WDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYP 994
            S F SVR   CV +G W+YEV + + GVMQ+GW T+  KF   E  G+GD   S  YDG R  +W N  SK +    W  GD I   +DL++ ++ ++ NG  L     ++       ++ A S         NFG   F +P
Sbjct:  349 SSFESVRCTFCVDSGVWYYEVTVITSGVMQIGWATKDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHSHPCWKEGDAIGFLLDLSKKQMIFYLNGHQLP-PEKQVFFSATSGFFAAASFMSYQQCEFNFGAKPFRHP 490

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BLAST of SMED30022562 vs. Ensembl Zebrafish
Match: ryr1b (ryanodine receptor 1b (skeletal) [Source:ZFIN;Acc:ZDB-GENE-070705-417])

HSP 1 Score: 66.6254 bits (161), Expect = 3.393e-11
Identity = 41/135 (30.37%), Postives = 64/135 (47.41%), Query Frame = -2

Query:  581 VYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDK--------IRVGPNIVYYPAVSLSQGDSITLNFGGSMFLY 961
            V +GKW++E    + G M++GW     +   E  +G    +Y ++GNR + W++ +  +G  W  GDV+ C IDL E  + +  NG+ L  ISD         I +G   +    + LSQ   I L    S   Y
Sbjct: 1084 VTSGKWYFEFEAVTTGEMRVGWARPNVRSDVE--LGSDELAYVFNGNRAQRWHIGNDPFGRQWQSGDVVGCMIDLIEMNIMFTLNGEML--ISDSGSEMAFKDIEIGDGFIPVCTLGLSQVGRINLGQNVSSLRY 1214

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BLAST of SMED30022562 vs. Ensembl Zebrafish
Match: RYR2 (ryanodine receptor 2a (cardiac) [Source:NCBI gene;Acc:100126126])

HSP 1 Score: 66.2402 bits (160), Expect = 4.772e-11
Identity = 34/117 (29.06%), Postives = 61/117 (52.14%), Query Frame = -2

Query:  695 QGHIKIDSQMTVLGLSDFSSVRAN--CCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSL 1039
            Q H + D  +  L    F   RA    CV  GKW++E+ + + G M++GW    C   +E G  +   ++ +DG + + W+  ++ +G +W  GDV+ C +D+ E  + +  NG+ L
Sbjct: 1048 QDHARED--VGNLSAERFRIFRAEKTYCVNGGKWYFELEVVTAGEMRVGWARPGCLPDQELGADE--QAFVFDGFKAQRWHQGNEHFGRSWQSGDVVGCMVDMNERTMMFTLNGEVL 1160

[Close]

BLAST of SMED30022562 vs. Ensembl Zebrafish
Match: RYR2 (ryanodine receptor 2a (cardiac) [Source:NCBI gene;Acc:100126126])

HSP 1 Score: 66.2402 bits (160), Expect = 4.774e-11
Identity = 34/117 (29.06%), Postives = 61/117 (52.14%), Query Frame = -2

Query:  695 QGHIKIDSQMTVLGLSDFSSVRAN--CCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSL 1039
            Q H + D  +  L    F   RA    CV  GKW++E+ + + G M++GW    C   +E G  +   ++ +DG + + W+  ++ +G +W  GDV+ C +D+ E  + +  NG+ L
Sbjct: 1066 QDHARED--VGNLSAERFRIFRAEKTYCVNGGKWYFELEVVTAGEMRVGWARPGCLPDQELGADE--QAFVFDGFKAQRWHQGNEHFGRSWQSGDVVGCMVDMNERTMMFTLNGEVL 1178

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BLAST of SMED30022562 vs. Ensembl Xenopus
Match: tsc22d2 (TSC22 domain family member 2 [Source:Xenbase;Acc:XB-GENE-978247])

HSP 1 Score: 256.529 bits (654), Expect = 3.945e-75
Identity = 134/403 (33.25%), Postives = 213/403 (52.85%), Query Frame = -2

Query:   29 LAHVFPEMMNNKHSLSVTNIDIF--LKEKITKHVDQADIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1222
            L  +FP      H  +      F  L+E + + V   +    +T     GRLGP TV  +         +  D  + V+G S+FSS+RA  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDTPDSY YDGNR++ WNV +  YG++W  GD+++C IDL E  + +  NG SLG     I  G  + Y+PA+SLS  +S+  NFG     YP++GY+P+Q     +L+K+Q L+GYL+  +   +D              +E    +  P   Q+  +    +  +++ N    L+   ++ E  LI  LL   +          +  +LD++W L+E   I   +  L+  ++  Y+ +P+ P+   Q  YL L +AI++H+K++ Y+L + L+
Sbjct:   39 LQRIFPATEGTSHGAAYRKPLTFQNLEEHLERLVSAGETTEDDTDQAAEGRLGPSTVVLDHTSGFEGLLLVDDDLLGVIGHSNFSSIRATTCVYKGKWLYEVLISSQGLMQIGWCTLSCRFNQEEGVGDTPDSYAYDGNRVRKWNVTTTNYGKSWAAGDIVSCLIDLDEGTISFCLNGVSLGTAFSDISRGSGMAYFPAISLSFKESVAFNFGSRPLRYPVEGYRPLQDPPTADLLKSQRLMGYLKNTLRTGIDV-------------QEGKLVDKDPATWQLQGEPTILITLAHIFNQFAPLMCKVYLVEDVLINFLLGILEKGGAVEEHPLIQHLLDLMWLLMEDYEIHECLKQLMMSLLRAYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKYLLSNVLF 428

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BLAST of SMED30022562 vs. Ensembl Xenopus
Match: tsc22d2 (TSC22 domain family member 2 [Source:Xenbase;Acc:XB-GENE-978247])

HSP 1 Score: 180.259 bits (456), Expect = 8.825e-49
Identity = 92/288 (31.94%), Postives = 152/288 (52.78%), Query Frame = -2

Query:   29 YCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYP--IDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 886
            +C F    GVGDTPDSY YDGNR++ WNV +  YG++W  GD+++C IDL E  + +  NG SLG     I  G  + Y+PA+SLS  +S+  NFG     YP  I+GY+P+Q     +L+K+Q L+GYL+  +   +D              +E    +  P   Q+  +    +  +++ N    L+   ++ E  LI  LL   +          +  +LD++W L+E   I   +  L+  ++  Y+ +P+ P+   Q  YL L +AI++H+K++ Y+L + L+
Sbjct:   35 HCTFYTGEGVGDTPDSYAYDGNRVRKWNVTTTNYGKSWAAGDIVSCLIDLDEGTISFCLNGVSLGTAFSDISRGSGMAYFPAISLSFKESVAFNFGSRPLRYPFIIEGYRPLQDPPTADLLKSQRLMGYLKNTLRTGIDV-------------QEGKLVDKDPATWQLQGEPTILITLAHIFNQFAPLMCKVYLVEDVLINFLLGILEKGGAVEEHPLIQHLLDLMWLLMEDYEIHECLKQLMMSLLRAYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKYLLSNVLF 309

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BLAST of SMED30022562 vs. Ensembl Xenopus
Match: tsc22d2 (TSC22 domain family member 2 [Source:Xenbase;Acc:XB-GENE-978247])

HSP 1 Score: 178.718 bits (452), Expect = 2.317e-48
Identity = 94/290 (32.41%), Postives = 154/290 (53.10%), Query Frame = -2

Query:   29 TEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYP--IDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 892
            T Y  F +E GVGDTPDSY YDGNR++ WNV +  YG++W  GD+++C IDL E  + +  NG SLG     I  G  + Y+PA+SLS  +S+  NFG     YP  I+GY+P+Q     +L+K+Q L+GYL+  +   +D              +E    +  P   Q+  +    +  +++ N    L+   ++ E  LI  LL   +          +  +LD++W L+E   I   +  L+  ++  Y+ +P+ P+   Q  YL L +AI++H+K++ Y+L + L+
Sbjct:    5 TGYTLFMQE-GVGDTPDSYAYDGNRVRKWNVTTTNYGKSWAAGDIVSCLIDLDEGTISFCLNGVSLGTAFSDISRGSGMAYFPAISLSFKESVAFNFGSRPLRYPFIIEGYRPLQDPPTADLLKSQRLMGYLKNTLRTGIDV-------------QEGKLVDKDPATWQLQGEPTILITLAHIFNQFAPLMCKVYLVEDVLINFLLGILEKGGAVEEHPLIQHLLDLMWLLMEDYEIHECLKQLMMSLLRAYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKYLLSNVLF 280

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BLAST of SMED30022562 vs. Ensembl Xenopus
Match: tsc22d2 (TSC22 domain family member 2 [Source:Xenbase;Acc:XB-GENE-978247])

HSP 1 Score: 177.178 bits (448), Expect = 9.768e-48
Identity = 92/288 (31.94%), Postives = 151/288 (52.43%), Query Frame = -2

Query:   29 TEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 892
            T Y  F +E GVGDTPDSY YDGNR++ WNV +  YG++W  GD+++C IDL E  + +  NG SLG     I  G  + Y+PA+SLS  +S+  NFG     YP   Y+P+Q     +L+K+Q L+GYL+  +   +D              +E    +  P   Q+  +    +  +++ N    L+   ++ E  LI  LL   +          +  +LD++W L+E   I   +  L+  ++  Y+ +P+ P+   Q  YL L +AI++H+K++ Y+L + L+
Sbjct:    5 TGYTLFMQE-GVGDTPDSYAYDGNRVRKWNVTTTNYGKSWAAGDIVSCLIDLDEGTISFCLNGVSLGTAFSDISRGSGMAYFPAISLSFKESVAFNFGSRPLRYPFIRYRPLQDPPTADLLKSQRLMGYLKNTLRTGIDV-------------QEGKLVDKDPATWQLQGEPTILITLAHIFNQFAPLMCKVYLVEDVLINFLLGILEKGGAVEEHPLIQHLLDLMWLLMEDYEIHECLKQLMMSLLRAYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKYLLSNVLF 278

[Close]

BLAST of SMED30022562 vs. Ensembl Xenopus
Match: tsc22d2 (TSC22 domain family member 2 [Source:Xenbase;Acc:XB-GENE-978247])

HSP 1 Score: 176.792 bits (447), Expect = 1.167e-47
Identity = 92/288 (31.94%), Postives = 151/288 (52.43%), Query Frame = -2

Query:   29 TEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 892
            T Y  F +E GVGDTPDSY YDGNR++ WNV +  YG++W  GD+++C IDL E  + +  NG SLG     I  G  + Y+PA+SLS  +S+  NFG     YP   Y+P+Q     +L+K+Q L+GYL+  +   +D              +E    +  P   Q+  +    +  +++ N    L+   ++ E  LI  LL   +          +  +LD++W L+E   I   +  L+  ++  Y+ +P+ P+   Q  YL L +AI++H+K++ Y+L + L+
Sbjct:    5 TGYTLFMQE-GVGDTPDSYAYDGNRVRKWNVTTTNYGKSWAAGDIVSCLIDLDEGTISFCLNGVSLGTAFSDISRGSGMAYFPAISLSFKESVAFNFGSRPLRYPFIRYRPLQDPPTADLLKSQRLMGYLKNTLRTGIDV-------------QEGKLVDKDPATWQLQGEPTILITLAHIFNQFAPLMCKVYLVEDVLINFLLGILEKGGAVEEHPLIQHLLDLMWLLMEDYEIHECLKQLMMSLLRAYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKYLLSNVLF 278

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BLAST of SMED30022562 vs. Ensembl Mouse
Match: Rnf123 (ring finger protein 123 [Source:MGI Symbol;Acc:MGI:2148796])

HSP 1 Score: 245.358 bits (625), Expect = 2.087e-71
Identity = 127/377 (33.69%), Postives = 210/377 (55.70%), Query Frame = -2

Query:   29 ITKHVDQ---ADIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1141
            + +HVDQ    D +  E++    GRLGP TV  +         +  D  + V+G S+F ++R+  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ G++P+Q     +LV+AQ L+G  + ++ + +D +             E    E      Q+  Q    L  +++ +H   L+   ++ E+ L+  LL   +    +  QS V  ILD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L ++I++H+K++ ++L + L+
Sbjct:   64 LPEHVDQLLQVDSEDNESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWVYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGFRPLQDPPFADLVRAQRLLGCFQAVLSVELDPV-------------EGRLVETESSEWQLQGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGVVEKGTPEQAQSVVHQILDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTMSILRHEKSRKFLLSNVLF 427

[Close]

BLAST of SMED30022562 vs. Ensembl Mouse
Match: Rnf123 (ring finger protein 123 [Source:MGI Symbol;Acc:MGI:2148796])

HSP 1 Score: 245.358 bits (625), Expect = 2.551e-71
Identity = 127/377 (33.69%), Postives = 210/377 (55.70%), Query Frame = -2

Query:   29 ITKHVDQ---ADIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1141
            + +HVDQ    D +  E++    GRLGP TV  +         +  D  + V+G S+F ++R+  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ G++P+Q     +LV+AQ L+G  + ++ + +D +             E    E      Q+  Q    L  +++ +H   L+   ++ E+ L+  LL   +    +  QS V  ILD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L ++I++H+K++ ++L + L+
Sbjct:   64 LPEHVDQLLQVDSEDNESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWVYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGFRPLQDPPFADLVRAQRLLGCFQAVLSVELDPV-------------EGRLVETESSEWQLQGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGVVEKGTPEQAQSVVHQILDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTMSILRHEKSRKFLLSNVLF 427

[Close]

Query:   29 ITKHVDQ---ADIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1141
            + +HVDQ    D +  E++    GRLGP TV  +         +  D  + V+G S+F ++R+  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ G++P+Q     +LV+AQ L+G  + ++ + +D +             E    E      Q+  Q    L  +++ +H   L+   ++ E+ L+  LL   +    +  QS V  ILD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L ++I++H+K++ ++L + L+
Sbjct:   64 LPEHVDQLLQVDSEDNESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWVYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGFRPLQDPPFADLVRAQRLLGCFQAVLSVELDPV-------------EGRLVETESSEWQLQGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGVVEKGTPEQAQSVVHQILDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTMSILRHEKSRKFLLSNVLF 427

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BLAST of SMED30022562 vs. Ensembl Mouse
Match: Rnf123 (ring finger protein 123 [Source:MGI Symbol;Acc:MGI:2148796])

HSP 1 Score: 244.973 bits (624), Expect = 2.574e-71
Identity = 127/377 (33.69%), Postives = 210/377 (55.70%), Query Frame = -2

Query:   29 ITKHVDQ---ADIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1141
            + +HVDQ    D +  E++    GRLGP TV  +         +  D  + V+G S+F ++R+  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ G++P+Q     +LV+AQ L+G  + ++ + +D +             E    E      Q+  Q    L  +++ +H   L+   ++ E+ L+  LL   +    +  QS V  ILD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L ++I++H+K++ ++L + L+
Sbjct:   64 LPEHVDQLLQVDSEDNESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWVYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGFRPLQDPPFADLVRAQRLLGCFQAVLSVELDPV-------------EGRLVETESSEWQLQGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGVVEKGTPEQAQSVVHQILDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTMSILRHEKSRKFLLSNVLF 427

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Query:   29 ITKHVDQ---ADIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1141
            + +HVDQ    D +  E++    GRLGP TV  +         +  D  + V+G S+F ++R+  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ G++P+Q     +LV+AQ L+G  + ++ + +D +             E    E      Q+  Q    L  +++ +H   L+   ++ E+ L+  LL   +    +  QS V  ILD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L ++I++H+K++ ++L + L+
Sbjct:   64 LPEHVDQLLQVDSEDNESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWVYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGFRPLQDPPFADLVRAQRLLGCFQAVLSVELDPV-------------EGRLVETESSEWQLQGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGVVEKGTPEQAQSVVHQILDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTMSILRHEKSRKFLLSNVLF 427

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BLAST of SMED30022562 vs. UniProt/SwissProt
Match: sp|D3ZXK7|RN123_RAT (E3 ubiquitin-protein ligase RNF123 OS=Rattus norvegicus OX=10116 GN=Rnf123 PE=1 SV=1)

HSP 1 Score: 245.358 bits (625), Expect = 1.615e-70
Identity = 126/375 (33.60%), Postives = 210/375 (56.00%), Query Frame = -2

Query:   29 ITKHVDQA-DIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1141
            + +HVDQ   +   E++    GRLGP TV  +         +  D  + V+G S+F ++R++ CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ G++P+Q     +LV+AQ L+G  + ++ + +D +             E    E      Q+  Q    L  +++ +H   L+   ++ E+ L+  LL   +    +  QS V  ILD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L +A+++H+K++ ++L + L+
Sbjct:   64 LPEHVDQLLQVDDEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSSTCVYKGKWVYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGFRPLQDPPFADLVRAQRLLGCFQTVLSVELDPV-------------EGRLVEKESSEWQLHGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPEQAQSVVHQILDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTMAVLRHEKSRKFLLSNVLF 425

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BLAST of SMED30022562 vs. UniProt/SwissProt
Match: sp|Q5XPI3|RN123_MOUSE (E3 ubiquitin-protein ligase RNF123 OS=Mus musculus OX=10090 GN=Rnf123 PE=1 SV=1)

HSP 1 Score: 244.973 bits (624), Expect = 1.801e-70
Identity = 127/377 (33.69%), Postives = 210/377 (55.70%), Query Frame = -2

Query:   29 ITKHVDQ---ADIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1141
            + +HVDQ    D +  E++    GRLGP TV  +         +  D  + V+G S+F ++R+  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ G++P+Q     +LV+AQ L+G  + ++ + +D +             E    E      Q+  Q    L  +++ +H   L+   ++ E+ L+  LL   +    +  QS V  ILD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L ++I++H+K++ ++L + L+
Sbjct:   64 LPEHVDQLLQVDSEDNESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWVYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGFRPLQDPPFADLVRAQRLLGCFQAVLSVELDPV-------------EGRLVETESSEWQLQGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGVVEKGTPEQAQSVVHQILDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTMSILRHEKSRKFLLSNVLF 427

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BLAST of SMED30022562 vs. UniProt/SwissProt
Match: sp|Q5XPI4|RN123_HUMAN (E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens OX=9606 GN=RNF123 PE=1 SV=1)

HSP 1 Score: 241.121 bits (614), Expect = 3.953e-69
Identity = 125/379 (32.98%), Postives = 209/379 (55.15%), Query Frame = -2

Query:   29 EKITKHVDQ---ADIKVVETKPLQFGRLGPETVSFNKMC---QGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1147
            + + +H+DQ    D +  E++    GRLGP TV  +         +  D  + V+G S+F ++R+  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDT +SY YDGNR++ WNV +  YG+AW  GD+++C IDL +  L +  NG SLG   + +  G  + Y+PA+SLS  +S+  NFG     YP+ GY+P+Q     +LV+AQ L+G    ++ + +D +             E    +      ++  Q    L  +++ +H   L+   ++ E+ L+  LL   +       QS V  +LD+LW  +E   +   +  L+  ++ LY+ +P+ P+   Q  YL L +AI++H+K++ ++L + L+
Sbjct:   62 QNLPEHLDQLLQVDNEEEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSTTCVYKGKWLYEVLISSQGLMQIGWCTISCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGYRPLQDPPSADLVRAQRLLGCFRAVLSVELDPV-------------EGRLLDKESSKWRLRGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPTQAQSVVHQVLDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTIAILRHEKSRKFLLSNVLF 427

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BLAST of SMED30022562 vs. UniProt/SwissProt
Match: sp|Q9SIZ8|RKP_ARATH (E3 ubiquitin-protein ligase RKP OS=Arabidopsis thaliana OX=3702 GN=RKP PE=2 SV=2)

HSP 1 Score: 179.104 bits (453), Expect = 9.824e-48
Identity = 92/210 (43.81%), Postives = 127/210 (60.48%), Query Frame = -2

Query:  554 IDIFLKEKITKHVDQADIKVVETKPLQFGR--LGPETVSFNK--MCQGHIKIDSQMTVL-GLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIR-VGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQ 1165
            I   +K + +K     D+ V + + +      +GP  V   +  +C G I+I     VL  L+ FSS RAN C++ GKW YEV L + G+ QLGW T  C FT++ GVGD  DSY +DG R+  WN  ++ YG++W  GDVI CCIDL   ++ ++RNG SLG     IR +GP   YYPA+SLSQG+   LNFG   F YP+DG++P+Q
Sbjct:   72 IRAVIKNQFSKLHGDLDVSVSQREGISVVHHGVGPPIVGLEEFSIC-GDIRIVKPPLVLESLALFSSARANACIWKGKWMYEVALETSGIQQLGWATLACPFTDQKGVGDADDSYAFDGRRVSKWNKEAEPYGQSWVAGDVIGCCIDLNCDEIYFYRNGVSLGAAFTGIRKLGPGFGYYPAISLSQGERCELNFGAYPFKYPVDGFQPLQ 280

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BLAST of SMED30022562 vs. UniProt/SwissProt
Match: sp|Q8BVR6|RSPRY_MOUSE (RING finger and SPRY domain-containing protein 1 OS=Mus musculus OX=10090 GN=Rspry1 PE=1 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 6.225e-16
Identity = 54/145 (37.24%), Postives = 71/145 (48.97%), Query Frame = -2

Query:  578 SDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKF--TEENGVGDTPDSYGYDGNRIKLW-NVLSKKY-GEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIV--YYPAVSLSQGDSITLNFGGSMFLYP 994
            S F SVR   CV  G W+YEV + + GVMQ+GW T   KF   E  G+GD   S  YDG R  +W N  SK +    W  GD +   +DL E ++ +F NG  L     + +V  + V  ++ A S         NFG   F YP
Sbjct:  345 SSFESVRCTFCVDTGVWYYEVTVVTSGVMQIGWATRDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHVHPCWKEGDTVGFLLDLNEKQMIFFLNGNQL---PPEKQVFSSTVSGFFAAASFMSYQQCEFNFGARPFKYP 486

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BLAST of SMED30022562 vs. TrEMBL
Match: K1Q5Z5 (B30.2/SPRY domain-containing protein OS=Crassostrea gigas OX=29159 GN=CGI_10004788 PE=4 SV=1)

HSP 1 Score: 285.419 bits (729), Expect = 2.798e-89
Identity = 145/363 (39.94%), Postives = 220/363 (60.61%), Query Frame = -2

Query:   23 GRLGPETVSFNKMCQ----GHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVD----CLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQS-HVSLILDMLWNLLEKESITTIVDWLLSGIV-TLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALYPF 1081
            GR+GP  V F++       G       + V   ++FS+VRANCCVY GKW YEV LWSKGVMQLGWCT  CKFT E GVGDT DSY YDG+R++ WN+ ++KYGEAW  GDVITC +D     + ++RNGKS+G     ++ G    Y+PAVSLS+ + +  NFG +   YPI+GY+P+Q    +++VK+Q LIG+LE+L    +      + +C    +             P  +  S +    LI +++   L  L+   ++ E CL+PL+LKFC T+   S  + H+  +LD++W+L++   I   +D L++ ++ + Y+ +P+T +F SQ+ YL L L +++H +T+ Y+L + LYP 
Sbjct:   30 GRIGPAEVVFDQKSMVAPLGLRLEPDNLGVTSHTNFSTVRANCCVYRGKWMYEVMLWSKGVMQLGWCTINCKFTFEEGVGDTKDSYSYDGSRLRKWNIRTQKYGEAWLAGDVITCALDCDNGTMTFYRNGKSMGEAFKNVKTGSGYAYFPAVSLSRNEHLRANFGATPLRYPIEGYEPLQAMPQEDVVKSQLLIGWLEKLTNTLIKEDKHLMDVCGIDQNVPPL---------PLGETRSKKSTALLICAHIFEKLAPLLKGPYVVECCLLPLMLKFCATTTDTSTTNPHIVKLLDLMWSLMQDHEIKPCMDTLMTSMLYSFYKTSPVTSDFSSQKTYLDLTLRVLQHSQTRRYLLLNILYPL 383

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BLAST of SMED30022562 vs. TrEMBL
Match: A0A2T7NUJ8 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_15318 PE=4 SV=1)

HSP 1 Score: 282.337 bits (721), Expect = 2.226e-81
Identity = 146/351 (41.60%), Postives = 223/351 (63.53%), Query Frame = -2

Query:   38 GRLGPETVSFNKMCQ-GHIKID-SQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSI-TLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILES 1081
            GR+GP  V  + +   G + ++  ++ V   S+FS+VRANCCVY GKW YE+ L SKGVMQLGWCT  C+F++E GVGDTPDSY YDG R++ WNV + KYGEAW  GDVI+C IDL    +E+FRNG S+GI    ++ GP   Y+PA SLS G++I  LNF  ++  +P+ GYKP+Q      + +AQ L+ YLERL+ I +D  K+ +  D++    +      A +  +IST    +LIA+++ + L  L+ N +I E+CL+P LL+         ++  +  +LD+ W LL+   +   ++ L + ++  Y+ TP+ P+FK+ +K+L L + I++HQ+T+ Y+L S
Sbjct:   20 GRIGPPDVILDILSNVGTLIVEPDRLGVASHSNFSTVRANCCVYRGKWIYEIMLGSKGVMQLGWCTLNCRFSQEEGVGDTPDSYAYDGTRLRKWNVKTFKYGEAWLSGDVISCAIDLDNGTVEFFRNGHSMGIAFSNVKTGPGYAYFPAASLSMGENIHNLNF-LNVITFPVPGYKPLQEPRWGEIRQAQALLRYLERLVSILLDDDKV-AGFDARIAKADITQLPLAEQRTRIST---AFLIAAHVFDKLGPLLKNLYIVEACLLPTLLQLSGGGVWHQSKPALLKMLDLFWALLQDFEVRQCMESLAAVLLASYRYTPVLPDFKNAKKFLALTVCILRHQRTRRYLLSS 365

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BLAST of SMED30022562 vs. TrEMBL
Match: A0A267DV69 (B30.2/SPRY domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009812g38 PE=4 SV=1)

HSP 1 Score: 281.182 bits (718), Expect = 7.505e-81
Identity = 154/450 (34.22%), Postives = 246/450 (54.67%), Query Frame = -2

Query:   29 RFTNISIFLDF*MNQQSILAHVFPEMMNNKHSL--SVTNIDIFLKEKITKHVDQADIKVVETKPLQFGRLGPETVSFNKMCQ--GHIKIDSQMT-VLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPI-DGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLK-ICSAADSQKEFKENYSEENAPKHD--------------------------QISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNL-KSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1276
            + T+ S+F     +  ++L HVFPE+++N  S   S+TN+  ++K+ I+  +D+A I     K    GRLGP  V  +      G + +D +   V+G S FS+ RANCCVY+GKW YE RL + G+MQ+GWCT  C F+ ENGVGDTP+S+ YDG+R++ WN     YGE W   DVITCCID  E  + ++RNG+SLG+  D +R+GP + Y+PA+S+++G +  LNFG   F YPI + Y+P+Q   ++   +   ++ +LERLIP+  D      SA        +   +  AP H                             S    CWLIAS+L+  +E  +T  +     ++PL+ KF D   L ++ Q H+ +I+  +   L+++S    +  ++S +       P +P++  Q   L ++LA+++H   + Y++ S L+
Sbjct:   14 KMTDSSMFTQ--ADHDALLNHVFPELLSNSKSSEWSLTNLSEYIKQTISDSIDEAKINSA-LKAFNSGRLGPTKVQLDSETNIGGQVLLDQRRQLVVGHSSFSTARANCCVYSGKWCYETRLCTGGLMQIGWCTLKCTFSRENGVGDTPNSFSYDGSRVRKWNAKFGTYGEPWLPHDVITCCIDCDEGVVSFYRNGRSLGVAFDNVRLGPGVAYFPALSVARGQAAFLNFGDVPFAYPIPEDYQPLQAPPLRLETRLVPVLSHLERLIPLAADTRNDALSATKVTGASLQEPVQPAAPMHSGNTGSASNVASAGVSSVATTASSSATTRSRDSTCWLIASHLVPLIEQGLTCDYTVAKYILPLMAKFSDIDCLPQARQCHLEVIVQYICTFLQRDSCQRALASIVSALFATCHSHP-SPDYAHQRTCLTILLAMLRHDCARRYLVSSVLF 459

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BLAST of SMED30022562 vs. TrEMBL
Match: A0A1I8I723 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 280.026 bits (715), Expect = 3.214e-80
Identity = 154/448 (34.38%), Postives = 245/448 (54.69%), Query Frame = -2

Query:   29 TNISIFLDF*MNQQSILAHVFPEMMNNKHS--LSVTNIDIFLKEKITKHVDQADIKVVETKPLQFGRLGPETVSFNKMCQ--GHIKIDSQ-MTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPI-DGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLK-ICSAADSQKEFKENYSEENAPKHD--------------------------QISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNL-KSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1270
            T+ S+F     +  ++L HVFPE+++N  S   S+TN+  ++K+ I+  +D+A I     K    GRLGP  V  +      G + +D +   V+G S FS+ RANCCVY+GKW YE RL + G+MQ+GWCT  C F+ ENGVGDTP+S+ YDG+R++ WN     YGE W   DVITCCID  E  + ++RNG+SLG+  D +R+GP + Y+PA+S+++G +  LNFG   F YPI + Y+P+Q   ++   +   ++ +LERLIP+  D      SA        +   +  AP H                             S    CWLIAS+L+  +E  +T  +     ++PL+ KF D   L ++ Q H+ +I+  +   L+++S    +  ++S +       P +P++  Q   L ++LA+++H   + Y++ S L+
Sbjct:    2 TDSSMFTQ--ADHDALLNHVFPELLSNSKSSEWSLTNLSEYIKQTISDSIDEAKINSA-LKAFNSGRLGPTKVQLDSETNIGGQVLLDQRRQLVVGHSSFSTARANCCVYSGKWCYETRLCTGGLMQIGWCTLKCTFSRENGVGDTPNSFSYDGSRVRKWNAKFGTYGEPWLPHDVITCCIDCDEGVVSFYRNGRSLGVAFDNVRLGPGVAYFPALSVARGQAAFLNFGDVPFAYPIPEDYQPLQAPPLRLETRLVPVLSHLERLIPLAADTRNDALSATKVTGASLQEPVQPAAPMHSGNTGSASNVASAGVSSVATTASSSATTRSRDSTCWLIASHLVPLIEQGLTCDYTVAKYILPLMAKFSDIDCLPQARQCHLEVIVQYICTFLQRDSCQRALASIVSALFATCHSHP-SPDYAHQRTCLTILLAMLRHDCARRYLVSSVLF 445

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BLAST of SMED30022562 vs. TrEMBL
Match: A0A267EZ75 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028554g1 PE=4 SV=1)

HSP 1 Score: 279.256 bits (713), Expect = 6.598e-80
Identity = 155/451 (34.37%), Postives = 248/451 (54.99%), Query Frame = -2

Query:   29 RFTNISIFLDF*MNQQSILAHVFPEMMNNKHS--LSVTNIDIFLKEKITKHVDQADIKVVETKPLQFGRLGPETVSFNKMCQ--GHIKIDSQ-MTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPI-DGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAAD--SQKEFKENYSEENAPKHD--------------------------QISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNL-KSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1276
            + T+ S+F     +  ++L HVFPE+++N  S   S+TN+  ++K+ I+  +D+A I     K    GRLGP  V  +      G + +D +   V+G S FS+ RANCCVY+GKW YE RL + G+MQ+GWCT  C F+ ENGVGDTP+S+ YDG+R++ WN     YGE W   DVITCCID  E  + ++RNG+SLG+  D +R+GP + Y+PA+S+++G +  LNFG   F YPI + Y+P+Q   ++   +   ++ +LERLIP+  D     SAA   +    +E   +  AP H                             S    CWLIAS+L+  +E  +T  +     ++PL+ KF D   L ++ Q H+ +I+  +   L+++S    +  ++S +       P + ++  Q   L ++LA+++H   + Y++ S L+
Sbjct:   14 KMTDSSMFTQ--ADHDALLNHVFPELLSNSKSSEWSLTNLSEYIKQTISDSIDEAKINSA-LKAFNSGRLGPTKVQLDSETNIGGQVLLDQRRQLVVGHSSFSTARANCCVYSGKWCYETRLCTGGLMQIGWCTLKCTFSRENGVGDTPNSFSYDGSRVRKWNAKFGTYGEPWLPHDVITCCIDCDEGVVSFYRNGRSLGVAFDNVRLGPGVAYFPALSVARGQAAFLNFGDVPFAYPIPEDYQPLQAPPLRLETRLVPVLSHLERLIPLAADTRNDASAATKVTGASLQEPV-QPAAPMHSGNTGSASNVASAGVSSVATTASSSATTRSRDSTCWLIASHLVPLIEQGLTCDYTVAKYILPLMAKFSDIDCLPQARQCHLEVIVQYICTFLQRDSCQRALASIVSALFATCHSHP-SRDYAHQRTCLTILLAMLRHDCARRYLVSSVLF 459

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BLAST of SMED30022562 vs. Ensembl Cavefish
Match: rnf123 (ring finger protein 123 [Source:ZFIN;Acc:ZDB-GENE-050208-529])

HSP 1 Score: 123.635 bits (309), Expect = 6.585e-30
Identity = 55/104 (52.88%), Postives = 73/104 (70.19%), Query Frame = -2

Query:  779 GRLGPETVSFNKMC--QGHIKIDSQM-TVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGE 1081
            GRLGP  V  +     +G + +D  +  V+G S+FSS+RA  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDTPDSY YDGNR++ WNV +  YG+
Sbjct:   72 GRLGPSPVVLDHTSGFEGLLFVDDDLLGVIGHSNFSSIRATTCVYKGKWVYEVLISSQGLMQIGWCTLNCRFNQEEGVGDTPDSYAYDGNRVRKWNVTTTNYGK 175

HSP 2 Score: 49.6766 bits (117), Expect = 4.922e-6
Identity = 26/117 (22.22%), Postives = 56/117 (47.86%), Query Frame = -2

Query:   44 QISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYIL 394
            Q+  +    +  +++ N+   L+   ++ E  L+  LL   +          +  +LD+ W L+E   +   +  L+  ++  Y+ +P+ P+   Q  YL L  AI+ H+K++ Y+L
Sbjct:  188 QLQGEPTVLVTLAHVFNYFAPLMCKVYLVEDVLMNFLLGILEGGGSVDEHPLIQQLLDLFWLLMEDFEVNECLKQLMMSLLRAYRFSPIIPDLGFQIHYLRLTTAILHHEKSRKYLL 304

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BLAST of SMED30022562 vs. Ensembl Cavefish
Match: rspry1 (ring finger and SPRY domain containing 1 [Source:NCBI gene;Acc:103038974])

HSP 1 Score: 84.7297 bits (208), Expect = 3.047e-17
Identity = 51/143 (35.66%), Postives = 71/143 (49.65%), Query Frame = -2

Query:  578 SDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFT--EENGVGDTPDSYGYDGNRIKLW-NVLSKKYGEA-WDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYP 994
            S F SVR   CV +G W+YEV + + GVMQ+GW T+  KF   E  G+GD   S  YDG R  +W N  SK +    W  GD I   +DL++ ++ +F NG  L     ++       ++ A S         NFG   F +P
Sbjct:  349 SSFESVRCTFCVDSGVWYYEVTVITSGVMQIGWATKDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHSHPCWKEGDAIGFLLDLSKKQMVFFLNGHQLP-PEKQVFSSATSGFFAAASFMSYQQCEFNFGAKPFRHP 490

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BLAST of SMED30022562 vs. Ensembl Cavefish
Match: rspry1 (ring finger and SPRY domain containing 1 [Source:NCBI gene;Acc:103038974])

HSP 1 Score: 84.3445 bits (207), Expect = 3.395e-17
Identity = 51/143 (35.66%), Postives = 71/143 (49.65%), Query Frame = -2

Query:  578 SDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFT--EENGVGDTPDSYGYDGNRIKLW-NVLSKKYGEA-WDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYP 994
            S F SVR   CV +G W+YEV + + GVMQ+GW T+  KF   E  G+GD   S  YDG R  +W N  SK +    W  GD I   +DL++ ++ +F NG  L     ++       ++ A S         NFG   F +P
Sbjct:  349 SSFESVRCTFCVDSGVWYYEVTVITSGVMQIGWATKDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHSHPCWKEGDAIGFLLDLSKKQMVFFLNGHQLP-PEKQVFSSATSGFFAAASFMSYQQCEFNFGAKPFRHP 490

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BLAST of SMED30022562 vs. Ensembl Cavefish
Match: ryr1b (ryanodine receptor 1b (skeletal) [Source:ZFIN;Acc:ZDB-GENE-070705-417])

HSP 1 Score: 71.2478 bits (173), Expect = 1.195e-12
Identity = 42/136 (30.88%), Postives = 66/136 (48.53%), Query Frame = -2

Query:  581 CVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDK--------IRVGPNIVYYPAVSLSQGDSITLNFGGSMFLY 964
             V +GKW++E    + G M++GW     +   E G  +   +Y ++GNR + W++ ++ +G  W  GDV+ C IDL E  + +  NG+ L  ISD         I +G   +   A+ LSQ   I L    S   Y
Sbjct: 1057 AVTSGKWYFEFEAVTTGEMRVGWARPNVRAGTELGADEL--AYVFNGNRAQRWHIGNEPFGRQWQSGDVVGCMIDLVEMNIMFTLNGEML--ISDSGSEMAFKDIEIGDGFIPVCALGLSQVGRINLGQNVSSLRY 1188

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BLAST of SMED30022562 vs. Ensembl Cavefish
Match: ryr1a (ryanodine receptor 1a (skeletal) [Source:ZFIN;Acc:ZDB-GENE-020108-2])

HSP 1 Score: 68.9366 bits (167), Expect = 6.322e-12
Identity = 43/136 (31.62%), Postives = 65/136 (47.79%), Query Frame = -2

Query:  581 CVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDK--------IRVGPNIVYYPAVSLSQGDSITLNFGGSMFLY 964
             V  GKW++E    + G M++GW        +E G  D   +Y ++G + + W+V S+ +G  W  GDV+ C IDLTE  + +  NG+ L  ISD         I +G   +   ++ LSQ   I L    S   Y
Sbjct: 1019 AVTQGKWYFEFEAVTVGEMRVGWARPSVHADKELGSDDL--AYVFNGFKAQRWHVGSEPFGRQWQSGDVVGCMIDLTEQNIMFTLNGEML--ISDSGSEMAFKDIEIGEGFIPVCSLGLSQVGRINLGQNVSSLRY 1150

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BLAST of SMED30022562 vs. Ensembl Sea Lamprey
Match: rspry1 (ring finger and SPRY domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-061026-2])

HSP 1 Score: 72.0182 bits (175), Expect = 3.410e-14
Identity = 42/104 (40.38%), Postives = 57/104 (54.81%), Query Frame = -2

Query:  695 SDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFT--EENGVGDTPDSYGYDGNRIKLW-NVLSKKYGEA-WDIGDVITCCIDLTEAKLEYFRNGKSL 994
            S F SVR   CV +G W+YEV + + GVMQ+GW T+  KF   E  G+GD   S  YDG R  +W N  SK +    W  GD +   +DL + ++ +  NG  L
Sbjct:  229 SSFESVRCTFCVDSGVWYYEVMVVTCGVMQIGWATKNSKFLNHEGYGIGDDEYSCAYDGCRRLIWYNAKSKPHAHPCWKEGDTVGFLLDLNKKQMVFSLNGTPL 332

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BLAST of SMED30022562 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003366.1 (pep scaffold:Pmarinus_7.0:GL477950:29474:49079:-1 gene:ENSPMAG00000003041.1 transcript:ENSPMAT00000003366.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.6994 bits (156), Expect = 1.484e-11
Identity = 50/175 (28.57%), Postives = 85/175 (48.57%), Query Frame = -2

Query:  566 ETVSFNKMCQGHIKIDSQMTVLGLSDFSSVRANCCVYN--GKWFYEVRLWSKG---VMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLW--NVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSL-SQGDSITLNFGGSMFLYPIDGY 1066
            + +S+  +  G++++  +       D +SVRAN  +    G +++EV++ SKG    M +G  T+        G      SYGY G+    +  +   + YG  +  GDV+ CC++L      Y +NG SLG     +   PN+  YP V L + G+ +  NFGG  F + I+ +
Sbjct:   71 DKLSYIGLSLGNLRVHYKGHGKTPKDAASVRANYPIPAACGIYYFEVKIVSKGRDGYMGIGLSTQEVNMNRLPGWDKY--SYGYHGDDGHSFCSSGAGRPYGPTFSTGDVVGCCVNLVNGTAFYTKNGHSLGTAFTDLP--PNL--YPTVGLQTPGEVVEANFGGQPFAFDIENH 239

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BLAST of SMED30022562 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010602.1 (pep scaffold:Pmarinus_7.0:GL476450:29:322425:-1 gene:ENSPMAG00000009553.1 transcript:ENSPMAT00000010602.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.5438 bits (153), Expect = 6.331e-11
Identity = 39/143 (27.27%), Postives = 67/143 (46.85%), Query Frame = -2

Query:  557 CVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGS---MFLYPI----DGYKPI 964
             V  GKW++E  L + G M++GW    C+   +  +G    ++ +DG + + W+   + +G AW  GDV+ C +DL ++ +    +G        +I  G    + P  SL       LNFG     +  +PI    +GY+P 
Sbjct: 1067 AVRTGKWYFEFELVTAGDMRVGWARPGCR--PDVALGSDDQAFVFDGLKSQKWHQGGEHFGRAWQPGDVVGCLVDLNDS-IMLDDSGSEFAFSELEIGEG----FMPICSLGLSQVGRLNFGKDATKLKYFPICGLQEGYEPF 1202

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BLAST of SMED30022562 vs. Ensembl Sea Lamprey
Match: HNRNPUL1 (heterogeneous nuclear ribonucleoprotein U like 1 [Source:HGNC Symbol;Acc:HGNC:17011])

HSP 1 Score: 48.521 bits (114), Expect = 2.355e-6
Identity = 35/110 (31.82%), Postives = 58/110 (52.73%), Query Frame = -2

Query:  599 VMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDL--TEAKLEYFRNGKSLGI---ISDKIRVGPNIVYYPAVSLSQGDSITLNFG 913
            V+++GW  + C       +G+   SYGY G+  K  +     YGE +  GDVI C ++    E +L +++NGK LG+   IS +   G  +  +P + L++  S+  NFG
Sbjct:   89 VVRVGWSLDSCSTQ----LGEEKFSYGYGGSAKKSVDCKFDDYGEEFSEGDVIGCFVNFEGEEVELSHYKNGKDLGVAFKISKEELAGRPL--FPHI-LTKNCSMEFNFG 191

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BLAST of SMED30022562 vs. Ensembl Nematostella
Match: EDO45063 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTP5])

HSP 1 Score: 231.491 bits (589), Expect = 3.345e-67
Identity = 121/317 (38.17%), Postives = 173/317 (54.57%), Query Frame = -2

Query:   23 CVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTK---LYILESALYPF 964
            C++ GKW YE+ L SKG+MQLGW T  CKFT E GVGDT DS+ YDG+R++ WNV + KYGE W  GDVI C IDL E  + Y RNGK LG+  D +R GP   Y+PA+SLS G+S  LNFG   F +P++   P+Q   + ++ K   L   LERL P      K+                   P      +     L  S++   L  L+T  ++ E  L+P LL+ C      ++Q  VS  LD++W  +E   +   ++ LL  ++  Y   P+T +FK+Q   L L L+I+KH  T+   +++L+  L+ F
Sbjct:    1 CLFAGKWMYEILLGSKGIMQLGWATLGCKFTNEEGVGDTADSFAYDGHRVRKWNVSTAKYGEEWMAGDVIGCAIDLDEGTISYSRNGKHLGVAFDNVRFGPGFAYFPAISLSYGESCHLNFGAYPFKFPMEYMNPLQDPPLSDVAKGTELTDCLERLFPAPDRIAKL-------------------PPALHCKSNVLSLLTTSHVFEKLGPLLTKGYVVEKVLLPYLLRSCSDCEPLADQPGVSNTLDLMWTCMEDFELEPCLEHLLFALIKAYWYQPVTMDFKTQTHCLKLALSILKHNMTRHALIHVLKFELFKF 298

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BLAST of SMED30022562 vs. Ensembl Nematostella
Match: EDO32967 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STL5])

HSP 1 Score: 119.013 bits (297), Expect = 3.628e-32
Identity = 58/115 (50.43%), Postives = 76/115 (66.09%), Query Frame = -2

Query:  764 ETKPLQFGRLGPETVSFNK--MCQGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIG 1102
            E + +  GR+GPE V  ++  +C G + I     +   S+FSS RAN CV  GKW YE+ L SKG+MQLGW T  CKFT E GVGDT DS+ YDG+R++ WNV + KYGE  ++G
Sbjct:   20 EQRAITDGRIGPEVVKIDRSSLC-GSMNIKDATELESQSNFSSARANICVCKGKWMYEILLGSKGIMQLGWATLGCKFTNEEGVGDTADSFAYDGHRVRKWNVSTAKYGEKSNVG 133

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BLAST of SMED30022562 vs. Ensembl Nematostella
Match: EDO42570 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S130])

HSP 1 Score: 98.9821 bits (245), Expect = 4.193e-22
Identity = 59/163 (36.20%), Postives = 82/163 (50.31%), Query Frame = -2

Query:  551 FSSVRANCCV---------YNGKWFYEVRLWSKGVMQLGWCTEYCKFTEEN--GVGDTPDSYGYDGNRIKLWNVLSKK-----YGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPI-DGYKPIQH 988
            F S+RA  CV         +   W+YEV L S G+MQ+GW TE C++  E   GVGD   S  +DG R K+W+    +     YG  W IGDV++C     E  + ++ NG+  G+    +    N  +YPAVSL+       NFG   F Y + D Y P+ H
Sbjct:  938 FESIRATYCVGHAMYKASPHPSGWYYEVILKSNGIMQIGWQTEECRYGPERGVGVGDDKHSCAFDGARCKIWSGPPSEQQNNDYGVEWQIGDVLSCLFSW-EGDVSFWLNGRDHGVAFTSLNTSIN--WYPAVSLAMDQHCIFNFGSMPFRYEVPDDYVPVCH 1097

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BLAST of SMED30022562 vs. Ensembl Nematostella
Match: EDO32929 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STM6])

HSP 1 Score: 63.1586 bits (152), Expect = 8.594e-11
Identity = 41/135 (30.37%), Postives = 69/135 (51.11%), Query Frame = -2

Query:  554 EVRLWSKGVMQLGWCTEYCKFTEE--NGVGDTPDSYGYDGNRIKLWNVLSKK-YGEAWDIGDVITCCIDLTEAKLEYFRNGK-SLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFG--GSMFLY-PIDGYKPIQ 937
            +V  +S G MQLGW  +      +   G GD   S+ YDG R   W+  +K+ YG  W  GD +   +DL + ++ +  NG  S  + +    + P+   YP +SL +G  ++++ G   + F Y P +GY P++
Sbjct:  110 KVLTFSGGYMQLGWADDGFSAAADTGQGCGDDSHSWAYDGTRTLKWHANAKEPYGRKWKEGDTVGIAVDLDQGEVSFSLNGDWSSPMGTAFTGITPDGGIYPCLSLIRGQRVSVHLGTPSNPFDYNPPEGYLPLR 244

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BLAST of SMED30022562 vs. Ensembl Nematostella
Match: EDO34873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN18])

HSP 1 Score: 59.3066 bits (142), Expect = 1.025e-9
Identity = 49/163 (30.06%), Postives = 80/163 (49.08%), Query Frame = -2

Query:  554 SSVRANCCVYNGKWFYEVRLWSK------------GVMQLGWCTEYCKFTEENGVGDTPDSYGYDGN-RIKLWNVLSKKYGEAWDIGDVITCCIDLTEAK--LEYFRNGKSLGIISDKIRVGP---NIVYYPAVSLSQGDSITLNFGG-SMFLYPIDGYKPIQ 985
            +  RA+  V +GK F+EV +  K             V+++GW  +         VG+   SYGY G  +  + N     YGE +   D+ITC IDL  +   + + +NG  LG+     R+GP   N  +YP V++ +   + +NFGG + +  PI G++ I+
Sbjct:   34 AGARASHGVKSGKIFFEVTVLDKLPVDLPETETTPHVVRVGWSVDSANLQ----VGEDALSYGYGGTAKCSVSNKFFD-YGERYSSNDIITCYIDLDASPKCIFFAKNGLYLGVA---FRLGPEAYNKAFYPHVTV-KNMRVRVNFGGFAPYFPPIQGFRMIE 187

[Close]

BLAST of SMED30022562 vs. Ensembl Medaka
Match: rnf123 (ring finger protein 123 [Source:NCBI gene;Acc:101163564])

HSP 1 Score: 251.521 bits (641), Expect = 1.128e-73
Identity = 122/354 (34.46%), Postives = 200/354 (56.50%), Query Frame = -2

Query:   29 GRLGPETVSFNKMC--QGHIKIDSQM-TVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALY 1081
            GR+GP+ V  +     +G + +D  +  V+G S+FSS+RA  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDTPDSY YDGNR++ WNV +  YG++W  GD++ C IDL E  + +  NG+SLG     I++GP I Y+PA+SLS  +S+  NFG     YP++GY P+Q     +L KA  L+G+++ ++  ++D              +E    E      ++  +    +  +++ NH   L+   ++ E  L+  LL   +          +  +LD+ W L+E   +   +  L+  ++  Y+ +P+ P+   Q  YL L  AI++H+K++ Y+L + L+
Sbjct:   36 GRVGPQPVVLDHTSGFEGLLFVDDDLLGVIGHSNFSSIRATTCVYKGKWAYEVLISSQGLMQIGWCTLNCRFNQEEGVGDTPDSYAYDGNRVRKWNVTTTNYGKSWAAGDIVNCLIDLDEGTITFCLNGQSLGTAFTNIKMGPGIAYFPAISLSFKESVAFNFGSRPLRYPVEGYLPLQDPPTADLTKAHKLLGFIKNVLSTSIDT-------------QEEKLLEKGCAMWKLHGEPTVLVTLAHIFNHFAPLMCKVYLVEDVLMNFLLGILEGGGSVDEHPLIQQLLDLFWLLMEDHEVNECLKQLMMSLLRAYRFSPIIPDLGFQIHYLRLTTAILRHEKSRKYLLNNVLF 376

[Close]

BLAST of SMED30022562 vs. Ensembl Medaka
Match: rnf123 (ring finger protein 123 [Source:NCBI gene;Acc:101163564])

HSP 1 Score: 243.817 bits (621), Expect = 5.301e-71
Identity = 133/407 (32.68%), Postives = 216/407 (53.07%), Query Frame = -2

Query:   11 LAHVFPEMMNNKHSLSVTNIDIFLKEKITKHVDQADIKVVETKPLQFGRLGPETVSFNKMC--QGHIKIDSQM-TVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALYPFYNLN 1222
            L HVFP         ++     F  + +  H+D+    + E +P   GR+GP+ V  +     +G + +D  +  V+G S+FSS+RA  CVY GKW YEV + S+G+MQ+GWCT  C+F +E GVGDTPDSY YDGNR++ WNV +  YG++W  GD++ C IDL E  + +  NG+SLG     I++GP I Y+PA+SLS  +S+  NFG         GY P+Q     +L KA  L+G+++ ++  ++D              +E    E      ++  +    +  +++ NH   L+   ++ E  L+  LL   +          +  +LD+ W L+E   +   +  L+  ++  Y+ +P+ P+   Q  YL L  AI++H+K++ Y+L + LYP   L 
Sbjct:   39 LHHVFPSAKPGAAPATLRKPLGF--QDLGAHLDRL---LSEEEPQVDGRVGPQPVVLDHTSGFEGLLFVDDDLLGVIGHSNFSSIRATTCVYKGKWAYEVLISSQGLMQIGWCTLNCRFNQE-GVGDTPDSYAYDGNRVRKWNVTTTNYGKSWAAGDIVNCLIDLDEGTITFCLNGQSLGTAFTNIKMGPGIAYFPAISLSFKESVAFNFG--------KGYLPLQDPPTADLTKAHKLLGFIKNVLSTSIDT-------------QEEKLLEKGCAMWKLHGEPTVLVTLAHIFNHFAPLMCKVYLVEDVLMNFLLGILEGGGSVDEHPLIQQLLDLFWLLMEDHEVNECLKQLMMSLLRAYRFSPIIPDLGFQIHYLRLTTAILRHEKSRKYLLNNVLYPLTPLR 418

[Close]

BLAST of SMED30022562 vs. Ensembl Medaka
Match: rspry1 (ring finger and SPRY domain containing 1 [Source:NCBI gene;Acc:101172328])

HSP 1 Score: 82.4185 bits (202), Expect = 1.488e-16
Identity = 50/143 (34.97%), Postives = 71/143 (49.65%), Query Frame = -2

Query:  578 SDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKF--TEENGVGDTPDSYGYDGNRIKLW-NVLSKKYGEA-WDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYP 994
            S F SVR   CV +G W+YEV + + GVMQ+GW T+  KF   E  G+GD   S  YDG R  +W N  SK +    W  GD I   +DL++ ++ ++ NG  L     ++       ++ A S         NFG   F +P
Sbjct:  317 SSFESVRCTFCVDSGVWYYEVTVITSGVMQIGWATKDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHSHPCWKEGDAIGFLLDLSKKQMIFYLNGNPLP-PEKQVFSSATSGFFAAASFMSYQQCEFNFGSKPFRHP 458

[Close]

BLAST of SMED30022562 vs. Ensembl Medaka
Match: rspry1 (ring finger and SPRY domain containing 1 [Source:NCBI gene;Acc:101172328])

HSP 1 Score: 82.4185 bits (202), Expect = 1.627e-16
Identity = 50/143 (34.97%), Postives = 71/143 (49.65%), Query Frame = -2

Query:  578 SDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKF--TEENGVGDTPDSYGYDGNRIKLW-NVLSKKYGEA-WDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYP 994
            S F SVR   CV +G W+YEV + + GVMQ+GW T+  KF   E  G+GD   S  YDG R  +W N  SK +    W  GD I   +DL++ ++ ++ NG  L     ++       ++ A S         NFG   F +P
Sbjct:  360 SSFESVRCTFCVDSGVWYYEVTVITSGVMQIGWATKDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHSHPCWKEGDAIGFLLDLSKKQMIFYLNGNPLP-PEKQVFSSATSGFFAAASFMSYQQCEFNFGSKPFRHP 501

[Close]

BLAST of SMED30022562 vs. Ensembl Medaka
Match: rspry1 (ring finger and SPRY domain containing 1 [Source:NCBI gene;Acc:101172328])

HSP 1 Score: 82.0333 bits (201), Expect = 1.912e-16
Identity = 50/143 (34.97%), Postives = 71/143 (49.65%), Query Frame = -2

Query:  578 SDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKF--TEENGVGDTPDSYGYDGNRIKLW-NVLSKKYGEA-WDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYP 994
            S F SVR   CV +G W+YEV + + GVMQ+GW T+  KF   E  G+GD   S  YDG R  +W N  SK +    W  GD I   +DL++ ++ ++ NG  L     ++       ++ A S         NFG   F +P
Sbjct:  360 SSFESVRCTFCVDSGVWYYEVTVITSGVMQIGWATKDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHSHPCWKEGDAIGFLLDLSKKQMIFYLNGNPLP-PEKQVFSSATSGFFAAASFMSYQQCEFNFGSKPFRHP 501

[Close]

BLAST of SMED30022562 vs. Planmine SMEST
Match: SMESG000005007.1 (SMESG000005007.1)

HSP 1 Score: 855.514 bits (2209), Expect = 0.000e+0
Identity = 413/413 (100.00%), Postives = 413/413 (100.00%), Query Frame = -2

Query:    2 MNQQSILAHVFPEMMNNKHSLSVTNIDIFLKEKITKHVDQADIKVVETKPLQFGRLGPETVSFNKMCQGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALYPFYNLNSMF 1240
            MNQQSILAHVFPEMMNNKHSLSVTNIDIFLKEKITKHVDQADIKVVETKPLQFGRLGPETVSFNKMCQGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALYPFYNLNSMF
Sbjct:    1 MNQQSILAHVFPEMMNNKHSLSVTNIDIFLKEKITKHVDQADIKVVETKPLQFGRLGPETVSFNKMCQGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLIPITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNHLENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKESITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILESALYPFYNLNSMF 413

[Close]

BLAST of SMED30022562 vs. Planmine SMEST
Match: SMESG000019493.1 (SMESG000019493.1)

HSP 1 Score: 76.6406 bits (187), Expect = 1.406e-14
Identity = 54/159 (33.96%), Postives = 88/159 (55.35%), Query Frame = -2

Query:  521 GKWFYEVR-LWSKGVMQLGWCTEY---------CKFTEENGVGDTPDSYGYDGNR-IKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISD---KIRVGPNIVYYPAVSLSQGDSITLNFGGSMF-LYPIDGYKPIQHQNIQNLVKAQ 952
            GK++YEV  L S G+ ++GW TE          C F    G G  PD +G  GN+  K++N   + YG++++ GDVI C +DL E K+++  NG+      D   ++R GP+  ++PAVSL + ++   NFG   F  YP + + P+ +   Q L +++
Sbjct:  744 GKYYYEVSPLESGGLARVGWSTEAGSLDLGTDKCGF----GYGADPDGFGLSGNQGKKMFNNDIENYGKSFNKGDVIGCFLDLDEGKVQWSLNGEIYAPAYDIPLELRNGPS-AFFPAVSL-KNNTAEFNFGEKAFKFYPGNEWTPLTYTPEQFLKESR 896

HSP 2 Score: 71.2478 bits (173), Expect = 6.996e-13
Identity = 46/144 (31.94%), Postives = 76/144 (52.78%), Query Frame = -2

Query:  578 RANCCVYN-GKWFYEVRLWSKGVMQLGWCTEYCKF---TEENGVGDTPDSYGYD-GNRIK---LWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGI---ISDKIRVGPNIVYYPAVSLSQGDSITLNFGGSMFLYP 976
            R+N  V   G++FYE R+   G+++LGW T        ++ENG G   D  G   G  +K   + +   K YG    +GD + C ++L    + +++NG+S+G+   I +++R  P    +P +S+  G  I  NFG S F+YP
Sbjct:  538 RSNKGVKTPGEYFYEARVLEDGLVRLGWSTNDASLKVGSDENGYGYGADEVGRGWGENVKGCTMHDSKIKDYGSGLFMGDYVGCRVNLNNGDVVWYKNGESMGVGYKIPEQLRKEP---MFPTLSVKDG-RIEFNFGDSPFVYP 677

[Close]

BLAST of SMED30022562 vs. Planmine SMEST
Match: SMESG000000646.1 (SMESG000000646.1)

HSP 1 Score: 68.9366 bits (167), Expect = 4.136e-12
Identity = 44/140 (31.43%), Postives = 64/140 (45.71%), Query Frame = -2

Query:  599 GLSDFSSVRANCC--VYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGK-SLGIISDKI---RVGPNIVYYPAVSLSQGDSITLNFG 1000
            G S   + RA     V +GKW+YEV L + G M+ GW      F     +G    SY +D      WN+ S  YG+    GDVI C +DL +  + +  NG+  +  +  +I    +  ++ Y P  S   G    LNFG
Sbjct: 1078 GSSAIRTFRAQSTWKVTSGKWYYEVELLTCGFMRFGWV--MVDFESGCEIGSNSQSYAFDTESATKWNLESGPYGKICQPGDVIGCMLDLQDQTITFSLNGELMMDPMGQEIAFKNMSCDMGYVPGFSFGPGQYAKLNFG 1215

HSP 2 Score: 51.2174 bits (121), Expect = 1.376e-6
Identity = 45/170 (26.47%), Postives = 76/170 (44.71%), Query Frame = -2

Query:  557 FSSVRANCCVYNGKWFYEVRLWS-------KGVMQLGWCTE--YCKFTEEN------GVGDTPDSYGYDGNRI-------KLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSL-GIISDKIRVGPNIVYYPAVSLSQGDSITLNFG---GSMFLYPIDGYKPI 988
            F  V      Y  KW+YE+R+ S       K ++++GW     +C F           VGD   S+G+DG  +       ++ NV+ +      + GD+I C +DLT   +++  N + + G   D      + ++YP VS S   S+ + FG   G +   P +GY  +
Sbjct:  653 FIGVEERSATYQ-KWYYEIRIDSIENVTNNKALLRVGWSNNEGFCPFPGGRQGWGSCAVGDDLFSFGFDGENLWTGGKPKRIRNVVQQPI---LNHGDIIGCMLDLTVPVIQFAINNEPVKGYFRD---FNIDGMFYPCVSASAKVSVRMIFGGPHGRLRYGPPEGYSAM 815

[Close]

BLAST of SMED30022562 vs. Planmine SMEST
Match: SMESG000000646.1 (SMESG000000646.1)

HSP 1 Score: 68.9366 bits (167), Expect = 4.172e-12
Identity = 44/140 (31.43%), Postives = 64/140 (45.71%), Query Frame = -2

Query:  599 GLSDFSSVRANCC--VYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGK-SLGIISDKI---RVGPNIVYYPAVSLSQGDSITLNFG 1000
            G S   + RA     V +GKW+YEV L + G M+ GW      F     +G    SY +D      WN+ S  YG+    GDVI C +DL +  + +  NG+  +  +  +I    +  ++ Y P  S   G    LNFG
Sbjct: 1078 GSSAIRTFRAQSTWKVTSGKWYYEVELLTCGFMRFGWV--MVDFESGCEIGSNSQSYAFDTESATKWNLESGPYGKICQPGDVIGCMLDLQDQTITFSLNGELMMDPMGQEIAFKNMSCDMGYVPGFSFGPGQYAKLNFG 1215

HSP 2 Score: 51.2174 bits (121), Expect = 1.412e-6
Identity = 45/170 (26.47%), Postives = 76/170 (44.71%), Query Frame = -2

Query:  557 FSSVRANCCVYNGKWFYEVRLWS-------KGVMQLGWCTE--YCKFTEEN------GVGDTPDSYGYDGNRI-------KLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSL-GIISDKIRVGPNIVYYPAVSLSQGDSITLNFG---GSMFLYPIDGYKPI 988
            F  V      Y  KW+YE+R+ S       K ++++GW     +C F           VGD   S+G+DG  +       ++ NV+ +      + GD+I C +DLT   +++  N + + G   D      + ++YP VS S   S+ + FG   G +   P +GY  +
Sbjct:  653 FIGVEERSATYQ-KWYYEIRIDSIENVTNNKALLRVGWSNNEGFCPFPGGRQGWGSCAVGDDLFSFGFDGENLWTGGKPKRIRNVVQQPI---LNHGDIIGCMLDLTVPVIQFAINNEPVKGYFRD---FNIDGMFYPCVSASAKVSVRMIFGGPHGRLRYGPPEGYSAM 815

[Close]

BLAST of SMED30022562 vs. Planmine SMEST
Match: SMESG000000646.1 (SMESG000000646.1)

HSP 1 Score: 68.9366 bits (167), Expect = 4.282e-12
Identity = 44/140 (31.43%), Postives = 64/140 (45.71%), Query Frame = -2

Query:  599 GLSDFSSVRANCC--VYNGKWFYEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGK-SLGIISDKI---RVGPNIVYYPAVSLSQGDSITLNFG 1000
            G S   + RA     V +GKW+YEV L + G M+ GW      F     +G    SY +D      WN+ S  YG+    GDVI C +DL +  + +  NG+  +  +  +I    +  ++ Y P  S   G    LNFG
Sbjct: 1078 GSSAIRTFRAQSTWKVTSGKWYYEVELLTCGFMRFGWV--MVDFESGCEIGSNSQSYAFDTESATKWNLESGPYGKICQPGDVIGCMLDLQDQTITFSLNGELMMDPMGQEIAFKNMSCDMGYVPGFSFGPGQYAKLNFG 1215

HSP 2 Score: 51.2174 bits (121), Expect = 1.364e-6
Identity = 45/170 (26.47%), Postives = 76/170 (44.71%), Query Frame = -2

Query:  557 FSSVRANCCVYNGKWFYEVRLWS-------KGVMQLGWCTE--YCKFTEEN------GVGDTPDSYGYDGNRI-------KLWNVLSKKYGEAWDIGDVITCCIDLTEAKLEYFRNGKSL-GIISDKIRVGPNIVYYPAVSLSQGDSITLNFG---GSMFLYPIDGYKPI 988
            F  V      Y  KW+YE+R+ S       K ++++GW     +C F           VGD   S+G+DG  +       ++ NV+ +      + GD+I C +DLT   +++  N + + G   D      + ++YP VS S   S+ + FG   G +   P +GY  +
Sbjct:  653 FIGVEERSATYQ-KWYYEIRIDSIENVTNNKALLRVGWSNNEGFCPFPGGRQGWGSCAVGDDLFSFGFDGENLWTGGKPKRIRNVVQQPI---LNHGDIIGCMLDLTVPVIQFAINNEPVKGYFRD---FNIDGMFYPCVSASAKVSVRMIFGGPHGRLRYGPPEGYSAM 815

The following BLAST results are available for this feature:

BLAST of SMED30022562 vs. Ensembl Human
BLAST of SMED30022562 vs. Ensembl Celegans
BLAST of SMED30022562 vs. Ensembl Fly
BLAST of SMED30022562 vs. Ensembl Zebrafish
BLAST of SMED30022562 vs. Ensembl Xenopus
BLAST of SMED30022562 vs. Ensembl Mouse
BLAST of SMED30022562 vs. UniProt/SwissProt
BLAST of SMED30022562 vs. TrEMBL
BLAST of SMED30022562 vs. Ensembl Cavefish
BLAST of SMED30022562 vs. Ensembl Sea Lamprey
BLAST of SMED30022562 vs. Ensembl Yeast
BLAST of SMED30022562 vs. Ensembl Nematostella
BLAST of SMED30022562 vs. Ensembl Medaka
BLAST of SMED30022562 vs. Planmine SMEST

BLAST of SMED30022562 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RNF123	5.482e-72	32.98	ring finger protein 123 [Source:HGNC Symbol;Acc:HG...	[more]
RNF123	8.232e-70	32.98	ring finger protein 123 [Source:HGNC Symbol;Acc:HG...	[more]
RNF123	4.621e-56	32.65	ring finger protein 123 [Source:HGNC Symbol;Acc:HG...	[more]
RSPRY1	1.608e-16	37.24	ring finger and SPRY domain containing 1 [Source:H...	[more]
RSPRY1	1.608e-16	37.24	ring finger and SPRY domain containing 1 [Source:H...	[more]

BLAST of SMED30022562 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
F16A11.1	7.549e-15	30.77	pep chromosome:WBcel235:I:9393953:9404024:-1 gene:...	[more]
F16A11.1	7.937e-15	30.77	pep chromosome:WBcel235:I:9393948:9398399:-1 gene:...	[more]
unc-68	1.277e-13	31.58	pep chromosome:WBcel235:V:6901697:6924961:-1 gene:...	[more]
unc-68	1.312e-13	31.58	pep chromosome:WBcel235:V:6901697:6929038:-1 gene:...	[more]
unc-68	1.323e-13	31.58	pep chromosome:WBcel235:V:6901697:6924961:-1 gene:...	[more]

BLAST of SMED30022562 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG6752	1.377e-61	31.64	gene:FBgn0038296 transcript:FBtr0306246	[more]
CG6752	1.377e-61	31.64	gene:FBgn0038296 transcript:FBtr0083029	[more]
RyR	3.817e-10	25.00	gene:FBgn0011286 transcript:FBtr0088640	[more]
ash2	4.399e-10	23.08	gene:FBgn0000139 transcript:FBtr0084659	[more]
RyR	4.581e-10	25.00	gene:FBgn0011286 transcript:FBtr0088638	[more]

BLAST of SMED30022562 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rnf123	7.070e-71	32.58	ring finger protein 123 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
rspry1	1.107e-16	34.97	ring finger and SPRY domain containing 1 [Source:Z...	[more]
ryr1b	3.393e-11	30.37	ryanodine receptor 1b (skeletal) [Source:ZFIN;Acc:...	[more]
RYR2	4.772e-11	29.06	ryanodine receptor 2a (cardiac) [Source:NCBI gene;...	[more]
RYR2	4.774e-11	29.06	ryanodine receptor 2a (cardiac) [Source:NCBI gene;...	[more]

BLAST of SMED30022562 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tsc22d2	3.945e-75	33.25	TSC22 domain family member 2 [Source:Xenbase;Acc:X...	[more]
tsc22d2	8.825e-49	31.94	TSC22 domain family member 2 [Source:Xenbase;Acc:X...	[more]
tsc22d2	2.317e-48	32.41	TSC22 domain family member 2 [Source:Xenbase;Acc:X...	[more]
tsc22d2	9.768e-48	31.94	TSC22 domain family member 2 [Source:Xenbase;Acc:X...	[more]
tsc22d2	1.167e-47	31.94	TSC22 domain family member 2 [Source:Xenbase;Acc:X...	[more]

BLAST of SMED30022562 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rnf123	2.087e-71	33.69	ring finger protein 123 [Source:MGI Symbol;Acc:MGI...	[more]
Rnf123	2.551e-71	33.69	ring finger protein 123 [Source:MGI Symbol;Acc:MGI...	[more]
Rnf123	2.551e-71	33.69	ring finger protein 123 [Source:MGI Symbol;Acc:MGI...	[more]
Rnf123	2.574e-71	33.69	ring finger protein 123 [Source:MGI Symbol;Acc:MGI...	[more]
Rnf123	2.574e-71	33.69	ring finger protein 123 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of SMED30022562 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|D3ZXK7\|RN123_RAT	1.615e-70	33.60	E3 ubiquitin-protein ligase RNF123 OS=Rattus norve...	[more]
sp\|Q5XPI3\|RN123_MOUSE	1.801e-70	33.69	E3 ubiquitin-protein ligase RNF123 OS=Mus musculus...	[more]
sp\|Q5XPI4\|RN123_HUMAN	3.953e-69	32.98	E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens...	[more]
sp\|Q9SIZ8\|RKP_ARATH	9.824e-48	43.81	E3 ubiquitin-protein ligase RKP OS=Arabidopsis tha...	[more]
sp\|Q8BVR6\|RSPRY_MOUSE	6.225e-16	37.24	RING finger and SPRY domain-containing protein 1 O...	[more]

BLAST of SMED30022562 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
K1Q5Z5	2.798e-89	39.94	B30.2/SPRY domain-containing protein OS=Crassostre...	[more]
A0A2T7NUJ8	2.226e-81	41.60	Uncharacterized protein OS=Pomacea canaliculata OX...	[more]
A0A267DV69	7.505e-81	34.22	B30.2/SPRY domain-containing protein (Fragment) OS...	[more]
A0A1I8I723	3.214e-80	34.38	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267EZ75	6.598e-80	34.37	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]

BLAST of SMED30022562 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rnf123	6.585e-30	52.88	ring finger protein 123 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
rspry1	3.047e-17	35.66	ring finger and SPRY domain containing 1 [Source:N...	[more]
rspry1	3.395e-17	35.66	ring finger and SPRY domain containing 1 [Source:N...	[more]
ryr1b	1.195e-12	30.88	ryanodine receptor 1b (skeletal) [Source:ZFIN;Acc:...	[more]
ryr1a	6.322e-12	31.62	ryanodine receptor 1a (skeletal) [Source:ZFIN;Acc:...	[more]

BLAST of SMED30022562 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
rspry1	3.410e-14	40.38	ring finger and SPRY domain containing 1 [Source:Z...	[more]
ENSPMAT00000003366.1	1.484e-11	28.57	pep scaffold:Pmarinus_7.0:GL477950:29474:49079:-1 ...	[more]
ENSPMAT00000010602.1	6.331e-11	27.27	pep scaffold:Pmarinus_7.0:GL476450:29:322425:-1 ge...	[more]
HNRNPUL1	2.355e-6	31.82	heterogeneous nuclear ribonucleoprotein U like 1 [...	[more]

BLAST of SMED30022562 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of SMED30022562 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO45063	3.345e-67	38.17	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32967	3.628e-32	50.43	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42570	4.193e-22	36.20	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32929	8.594e-11	30.37	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34873	1.025e-9	30.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SMED30022562 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rnf123	1.128e-73	34.46	ring finger protein 123 [Source:NCBI gene;Acc:1011...	[more]
rnf123	5.301e-71	32.68	ring finger protein 123 [Source:NCBI gene;Acc:1011...	[more]
rspry1	1.488e-16	34.97	ring finger and SPRY domain containing 1 [Source:N...	[more]
rspry1	1.627e-16	34.97	ring finger and SPRY domain containing 1 [Source:N...	[more]
rspry1	1.912e-16	34.97	ring finger and SPRY domain containing 1 [Source:N...	[more]

BLAST of SMED30022562 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000005007.1	0.000e+0	100.00	SMESG000005007.1	[more]
SMESG000019493.1	1.406e-14	33.96	SMESG000019493.1	[more]
SMESG000000646.1	4.136e-12	31.43	SMESG000000646.1	[more]
SMESG000000646.1	4.172e-12	31.43	SMESG000000646.1	[more]
SMESG000000646.1	4.282e-12	31.43	SMESG000000646.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30022562 ID=SMED30022562|Name=SMED30022562|organism=Schmidtea mediterranea sexual|type=transcript|length=1283bp
TAAACATAGAATTTAAATTATAAAAAGGATATAATGCACTTTCAAGAATG
TACAATTTCGTTTTCTGATGTTTCACAATCGCTAAAATCAAATAGAGATA
TTTTTCTTGAGATTTGAAGTTCGGAGTAAGGGGAGTGCATTGGTATAAAG
TCACGATTCCTGATAACAGCCAATCAACAATTGTGGTGATGCTTTCCTTT
TCAAGCAAATTCCATAACATATCAAGAATCAGTGATACGTGACTCTGGTT
GCTTTTTAAATTAGAAGTATCACAAAATTTGAGAAGCAACGGAATCAAAC
AGCTTTCATTGATAAATCTATTAGTAACCAAATTTTCTAAATGATTCATT
AAATTACTAGCGATGAGCCAACAACAACACTGAGTACTAATTTGATCATG
TTTTGGTGCGTTTTCTTCGGAATAATTTTCTTTGAATTCTTTCTGACTAT
CAGCAGCAGAACATATTTTCAAACAATCCACAGTTATTGGGATCAGCCTT
TCCAAGTAACCAATCAAACATTGAGCTTTCACTAAATTTTGAATATTCTG
GTGTTGAATAGGTTTATAACCATCAATTGGGTATAGAAACATAGATCCAC
CAAAGTTCAATGTTATGCTGTCACCTTGCGATAAACTGACAGCCGGATAG
TAGACAATATTGGGTCCCACTCGAATTTTATCACTTATAATTCCTAACGA
TTTCCCGTTTCTGAAATATTCCAATTTAGCCTCAGTTAAGTCAATACAGC
AAGTAATGACGTCTCCAATGTCCCATGCTTCTCCGTATTTTTTACTGAGA
ACATTCCATAGTTTAATACGATTACCGTCATATCCATAAGAATCAGGGGT
ATCGCCGACACCATTCTCTTCTGTGAATTTGCAATATTCCGTGCACCAGC
CCAATTGCATAACACCTTTTGACCATAATCGTACTTCATAAAACCATTTT
CCATTATAAACACAGCAATTAGCTCGCACAGAACTAAAATCACTTAAACC
TAAAACTGTCATTTGACTGTCAATTTTAATATGCCCTTGGCACATTTTAT
TAAAAGAAACCGTTTCAGGACCTAGTCTACCAAATTGTAACGGTTTCGTT
TCAACCACCTTAATATCAGCTTGATCCACATGTTTGGTGATTTTTTCTTT
TAAAAAAATATCAATGTTAGTCACTGATAGACTATGTTTGTTATTCATCA
TTTCTGGAAACACATGAGCTAATATGCTTTGTTGATTCATCTAAAAATCG
AGAAAAATAGAAATATTTGTGAAACGTTCTATT

protein sequence of SMED30022562-orf-1

>SMED30022562-orf-1 ID=SMED30022562-orf-1|Name=SMED30022562-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=413bp
MNQQSILAHVFPEMMNNKHSLSVTNIDIFLKEKITKHVDQADIKVVETKP
LQFGRLGPETVSFNKMCQGHIKIDSQMTVLGLSDFSSVRANCCVYNGKWF
YEVRLWSKGVMQLGWCTEYCKFTEENGVGDTPDSYGYDGNRIKLWNVLSK
KYGEAWDIGDVITCCIDLTEAKLEYFRNGKSLGIISDKIRVGPNIVYYPA
VSLSQGDSITLNFGGSMFLYPIDGYKPIQHQNIQNLVKAQCLIGYLERLI
PITVDCLKICSAADSQKEFKENYSEENAPKHDQISTQCCCWLIASNLMNH
LENLVTNRFINESCLIPLLLKFCDTSNLKSNQSHVSLILDMLWNLLEKES
ITTIVDWLLSGIVTLYQCTPLTPNFKSQEKYLYLILAIVKHQKTKLYILE
SALYPFYNLNSMF

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR043136	B30.2/SPRY_sf
IPR003877	SPRY_dom
IPR001870	B30.2/SPRY
IPR013320	ConA-like_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003877	SPRY domain	SMART	SM00449	SPRY_3	coord: 96..217 e-value: 1.1E-26 score: 104.7
IPR003877	SPRY domain	PFAM	PF00622	SPRY	coord: 98..215 e-value: 4.1E-21 score: 75.3
IPR043136	B30.2/SPRY domain superfamily	GENE3D	G3DSA:2.60.120.920		coord: 64..243 e-value: 3.0E-43 score: 149.8
None	No IPR available	PANTHER	PTHR13363	RING FINGER AND SRY DOMAIN-CONTAINING	coord: 54..285
IPR001870	B30.2/SPRY domain	PROSITE	PS50188	B302_SPRY	coord: 23..218 score: 15.475
IPR013320	Concanavalin A-like lectin/glucanase domain superfamily	SUPERFAMILY	SSF49899	Concanavalin A-like lectins/glucanases	coord: 83..229

Main menu

SMED30022562

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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