GTPase activating protein

Overview
NameGTPase activating protein
Smed IDSMED30022535
Length (bp)1541
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of GTPase activating protein (SMED30022535) t-SNE clustered cells

Violin plots show distribution of expression levels for GTPase activating protein (SMED30022535) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of GTPase activating protein (SMED30022535) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for GTPase activating protein (SMED30022535) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30022535

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30022535h1SMcG0002260 Contig236GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30022535h1SMcG0002260 Contig236GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
nervous systemSMED30022535h1SMcG0002260 dd_Smed_v4_316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30022535h1SMcG0002260 dd_Smed_v4_316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30022535h1SMcG0002260 dd_Smed_v4_316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30022535h1SMcG0002260 dd_Smed_v4_316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30022535h1SMcG0002259 dd_Smed_v4_316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30022535h1SMcG0002259 dd_Smed_v4_316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30022535h1SMcG0002259 dd_Smed_v4_316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30022535h1SMcG0002259 dd_Smed_v4_316_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of GTPase activating protein vs. Ensembl Human
Match: G3BP1 (G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292])

HSP 1 Score: 103.605 bits (257), Expect = 4.276e-23
Identity = 56/138 (40.58%), Postives = 81/138 (58.70%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVR----------DDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V           D +Y  GQ EIH+  M+   +NC   +  +DA  +    +++QV G ++NN   LRRFMQ+F+L  E  + N FYV NDIFRYQD+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVY--GQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF 138

HSP 2 Score: 87.8113 bits (216), Expect = 7.027e-18
Identity = 47/108 (43.52%), Postives = 70/108 (64.81%), Query Frame = 2 
Query:  923 VKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQKMGNSRATYKAGRR*N 1243
            ++P+  + +PD HQLF+GNLP  + + ELK+FF + YG V ++RI      N G  LPNFGF+VF + E V+++L ++PI +    RLNVE+K   +RA  +  RR N
Sbjct:  328 IEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQS-YGNVVELRI------NSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEK--KTRAAREGDRRDN 426
[Close]
BLAST of GTPase activating protein vs. Ensembl Human
Match: G3BP1 (G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292])

HSP 1 Score: 103.605 bits (257), Expect = 4.276e-23
Identity = 56/138 (40.58%), Postives = 81/138 (58.70%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVR----------DDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V           D +Y  GQ EIH+  M+   +NC   +  +DA  +    +++QV G ++NN   LRRFMQ+F+L  E  + N FYV NDIFRYQD+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVY--GQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF 138

HSP 2 Score: 87.8113 bits (216), Expect = 7.027e-18
Identity = 47/108 (43.52%), Postives = 70/108 (64.81%), Query Frame = 2 
Query:  923 VKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQKMGNSRATYKAGRR*N 1243
            ++P+  + +PD HQLF+GNLP  + + ELK+FF + YG V ++RI      N G  LPNFGF+VF + E V+++L ++PI +    RLNVE+K   +RA  +  RR N
Sbjct:  328 IEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQS-YGNVVELRI------NSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEK--KTRAAREGDRRDN 426
[Close]
BLAST of GTPase activating protein vs. Ensembl Human
Match: G3BP2 (G3BP stress granule assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:30291])

HSP 1 Score: 95.9005 bits (237), Expect = 2.888e-22
Identity = 51/136 (37.50%), Postives = 79/136 (58.09%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + A G        Q++IH   ++L  S C   +  +DA  +    +++QV G ++N+G   R+FMQ+F+L  E  + N FYV ND+FRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVF 138
[Close]
BLAST of GTPase activating protein vs. Ensembl Human
Match: G3BP2 (G3BP stress granule assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:30291])

HSP 1 Score: 93.2041 bits (230), Expect = 6.714e-22
Identity = 51/136 (37.50%), Postives = 79/136 (58.09%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + A G        Q++IH   ++L  S C   +  +DA  +    +++QV G ++N+G   R+FMQ+F+L  E  + N FYV ND+FRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVF 138
[Close]
BLAST of GTPase activating protein vs. Ensembl Human
Match: G3BP1 (G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292])

HSP 1 Score: 91.2781 bits (225), Expect = 3.521e-21
Identity = 55/140 (39.29%), Postives = 78/140 (55.71%), Query Frame = 2 
Query:  128 VSQEFVLQFYTIMNKQPGSLH----------RFYKEESTLVR----------DDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            V +EFV Q+YT++N+ P  LH          RFY + S+ V           D +Y  GQ EIH+  M+   +NC   +  +DA  +    +++QV G ++NN   LRRFMQ+F+L  E  + N FYV NDIFRYQD+ F
Sbjct:   11 VGREFVRQYYTLLNQAPDMLHSLHIGYHMIIRFYGKNSSYVHGGLDSNGKPADAVY--GQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF 148
[Close]
BLAST of GTPase activating protein vs. Ensembl Celegans
Match: gtbp-1 (Ras-Gtpase-activating protein SH3 (Three) domain-Binding Protein [Source:UniProtKB/TrEMBL;Acc:Q21351])

HSP 1 Score: 60.077 bits (144), Expect = 1.859e-9
Identity = 43/140 (30.71%), Postives = 71/140 (50.71%), Query Frame = 2 
Query:   77 NGDYITVVNMDRDLITTVSQ---EFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNL-ELSNCKAVVLSLDAVKS-HGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTF 481
            NG+  +   ++   +T   Q    F  QFY  +++   ++ +FY  ES    DD    G  EI K Y +L E ++ K  + S+    + H + ++I V G +     +LR F+QSFLL +Q    +YV +D F+Y D+ F
Sbjct:   16 NGNLTSTAPVEPLSLTAAEQVGGAFCHQFYITVSENRKAITKFYGHESKFYLDDQVVTGSQEIVKLYNHLPETTHFK--IQSIKGYPTPHKQGVIINVIGTV-----NLRPFLQSFLLGQQGQKKYYVESDAFQYIDKFF 148
[Close]
BLAST of GTPase activating protein vs. Ensembl Celegans
Match: rbm-34 (RNA Binding Motif protein homolog [Source:UniProtKB/TrEMBL;Acc:Q95QL3])

HSP 1 Score: 49.2914 bits (116), Expect = 4.711e-6
Identity = 34/115 (29.57%), Postives = 54/115 (46.96%), Query Frame = 2 
Query:  857 QKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKM 1201
            +K +  NG  +D    R + V  K +    +  +  +FVGNLP  +TE+ L  FFS + G V+ VRI + + + +GK    F F+ F     V   L  + I      L + + M
Sbjct:  215 EKALKYNGTKLDDHVIRVDKVGSKKK---EFGKDMAIFVGNLPFEITEDALITFFSAQIGPVEAVRIVRDKDTGKGK---GFAFVNFKQDSSVSLALSMETIKMEKRDLRITKVM 323
[Close]
BLAST of GTPase activating protein vs. Ensembl Fly
Match: rin (gene:FBgn0015778 transcript:FBtr0082799)

HSP 1 Score: 112.849 bits (281), Expect = 5.164e-26
Identity = 57/141 (40.43%), Postives = 86/141 (60.99%), Query Frame = 2 
Query:  125 TVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI-YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIH 544
            +V +EFV Q+YT++NK P  LHRFY   S+ +  +     GQ EIH     L  ++C A +  +DA  + G  +++QVTGE++N+G  +RRF Q+F+L  Q    +YV NDIFRYQD    +ED ++    E  S+N++ H
Sbjct:   15 SVGREFVRQYYTLLNKAPNHLHRFYNHNSSYIHGESKLVVGQREIHNRIQQLNFNDCHAKISQVDAQATLGNGVVVQVTGELSNDGQPMRRFTQTFVLAAQSPKKYYVHNDIFRYQD--LYIEDEQD---GESRSENDEEH 150

HSP 2 Score: 58.151 bits (139), Expect = 1.330e-8
Identity = 33/99 (33.33%), Postives = 57/99 (57.58%), Query Frame = 2 
Query:  938 TLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLP-------NFGFLVFHNHEVVEEILKHKPIYYS-----SHRLNVEQK 1198
            T  + D  QLF+GN+P + +E++L+E FS ++G V ++RI     S  G  +P       N+GF+ + + E V++ L + P+Y+        +LNVE+K
Sbjct:  486 TQQFGDNQQLFLGNIPHHASEDDLREIFS-RFGNVLELRI----LSKAGNKVPPGMRSPLNYGFITYDDPEAVQKCLANCPLYFPENSPDGQKLNVEEK 579
[Close]
BLAST of GTPase activating protein vs. Ensembl Fly
Match: rin (gene:FBgn0015778 transcript:FBtr0346347)

HSP 1 Score: 112.849 bits (281), Expect = 5.164e-26
Identity = 57/141 (40.43%), Postives = 86/141 (60.99%), Query Frame = 2 
Query:  125 TVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI-YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIH 544
            +V +EFV Q+YT++NK P  LHRFY   S+ +  +     GQ EIH     L  ++C A +  +DA  + G  +++QVTGE++N+G  +RRF Q+F+L  Q    +YV NDIFRYQD    +ED ++    E  S+N++ H
Sbjct:   15 SVGREFVRQYYTLLNKAPNHLHRFYNHNSSYIHGESKLVVGQREIHNRIQQLNFNDCHAKISQVDAQATLGNGVVVQVTGELSNDGQPMRRFTQTFVLAAQSPKKYYVHNDIFRYQD--LYIEDEQD---GESRSENDEEH 150

HSP 2 Score: 58.151 bits (139), Expect = 1.330e-8
Identity = 33/99 (33.33%), Postives = 57/99 (57.58%), Query Frame = 2 
Query:  938 TLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLP-------NFGFLVFHNHEVVEEILKHKPIYYS-----SHRLNVEQK 1198
            T  + D  QLF+GN+P + +E++L+E FS ++G V ++RI     S  G  +P       N+GF+ + + E V++ L + P+Y+        +LNVE+K
Sbjct:  486 TQQFGDNQQLFLGNIPHHASEDDLREIFS-RFGNVLELRI----LSKAGNKVPPGMRSPLNYGFITYDDPEAVQKCLANCPLYFPENSPDGQKLNVEEK 579
[Close]
BLAST of GTPase activating protein vs. Ensembl Fly
Match: rin (gene:FBgn0015778 transcript:FBtr0346346)

HSP 1 Score: 112.849 bits (281), Expect = 5.164e-26
Identity = 57/141 (40.43%), Postives = 86/141 (60.99%), Query Frame = 2 
Query:  125 TVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI-YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIH 544
            +V +EFV Q+YT++NK P  LHRFY   S+ +  +     GQ EIH     L  ++C A +  +DA  + G  +++QVTGE++N+G  +RRF Q+F+L  Q    +YV NDIFRYQD    +ED ++    E  S+N++ H
Sbjct:   15 SVGREFVRQYYTLLNKAPNHLHRFYNHNSSYIHGESKLVVGQREIHNRIQQLNFNDCHAKISQVDAQATLGNGVVVQVTGELSNDGQPMRRFTQTFVLAAQSPKKYYVHNDIFRYQD--LYIEDEQD---GESRSENDEEH 150

HSP 2 Score: 58.151 bits (139), Expect = 1.330e-8
Identity = 33/99 (33.33%), Postives = 57/99 (57.58%), Query Frame = 2 
Query:  938 TLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLP-------NFGFLVFHNHEVVEEILKHKPIYYS-----SHRLNVEQK 1198
            T  + D  QLF+GN+P + +E++L+E FS ++G V ++RI     S  G  +P       N+GF+ + + E V++ L + P+Y+        +LNVE+K
Sbjct:  486 TQQFGDNQQLFLGNIPHHASEDDLREIFS-RFGNVLELRI----LSKAGNKVPPGMRSPLNYGFITYDDPEAVQKCLANCPLYFPENSPDGQKLNVEEK 579
[Close]
BLAST of GTPase activating protein vs. Ensembl Fly
Match: rin (gene:FBgn0015778 transcript:FBtr0082797)

HSP 1 Score: 112.849 bits (281), Expect = 5.164e-26
Identity = 57/141 (40.43%), Postives = 86/141 (60.99%), Query Frame = 2 
Query:  125 TVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI-YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIH 544
            +V +EFV Q+YT++NK P  LHRFY   S+ +  +     GQ EIH     L  ++C A +  +DA  + G  +++QVTGE++N+G  +RRF Q+F+L  Q    +YV NDIFRYQD    +ED ++    E  S+N++ H
Sbjct:   15 SVGREFVRQYYTLLNKAPNHLHRFYNHNSSYIHGESKLVVGQREIHNRIQQLNFNDCHAKISQVDAQATLGNGVVVQVTGELSNDGQPMRRFTQTFVLAAQSPKKYYVHNDIFRYQD--LYIEDEQD---GESRSENDEEH 150

HSP 2 Score: 58.151 bits (139), Expect = 1.330e-8
Identity = 33/99 (33.33%), Postives = 57/99 (57.58%), Query Frame = 2 
Query:  938 TLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLP-------NFGFLVFHNHEVVEEILKHKPIYYS-----SHRLNVEQK 1198
            T  + D  QLF+GN+P + +E++L+E FS ++G V ++RI     S  G  +P       N+GF+ + + E V++ L + P+Y+        +LNVE+K
Sbjct:  486 TQQFGDNQQLFLGNIPHHASEDDLREIFS-RFGNVLELRI----LSKAGNKVPPGMRSPLNYGFITYDDPEAVQKCLANCPLYFPENSPDGQKLNVEEK 579
[Close]
BLAST of GTPase activating protein vs. Ensembl Zebrafish
Match: zgc:56304 (zgc:56304 [Source:ZFIN;Acc:ZDB-GENE-040426-2698])

HSP 1 Score: 107.842 bits (268), Expect = 3.407e-27
Identity = 55/142 (38.73%), Postives = 83/142 (58.45%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI--------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQD--LGNFYVLNDIFRYQDQTFKVEDVE 499
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   +           GQ EIHK  M+L+ S C   +  +DA  + G  +++QV GE++N+G  +RRFMQ+F+L  +   +  FYV NDIFRY+++ F   + E
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDYLHRFYGRNSSYVHGGLDSNGKPEEAVYGQAEIHKKVMSLQFSECHTKIRHVDAHATLGDGVVVQVMGELSNSGRPMRRFMQTFVLAPEGSAVNKFYVHNDIFRYEEEVFGDSEAE 144
[Close]
BLAST of GTPase activating protein vs. Ensembl Zebrafish
Match: zgc:56304 (zgc:56304 [Source:ZFIN;Acc:ZDB-GENE-040426-2698])

HSP 1 Score: 110.153 bits (274), Expect = 2.393e-25
Identity = 54/136 (39.71%), Postives = 82/136 (60.29%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQD--LGNFYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + + G        Q EIHK  M+L+ S C   +  +DA  + G  +++QV GE++N+G  +RRFMQ+F+L  +   +  FYV NDIFRY+++ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDYLHRFYGRNSSYVHGGLDSNGKPEEAVYGQAEIHKKVMSLQFSECHTKIRHVDAHATLGDGVVVQVMGELSNSGRPMRRFMQTFVLAPEGSAVNKFYVHNDIFRYEEEVF 138

HSP 2 Score: 85.1149 bits (209), Expect = 3.927e-17
Identity = 45/90 (50.00%), Postives = 59/90 (65.56%), Query Frame = 2 
Query:  932 QSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            + +  YPD HQLFVGNLP ++ E ELK+FF T +G V ++RI    T   G  LPNFGF+VF + + V+ IL  KPI +    RLNVE+K
Sbjct:  354 RRSFRYPDSHQLFVGNLPHDIDEGELKDFFMT-FGNVVEMRIN---TKGVGGKLPNFGFVVFDDSDPVQRILGAKPIMFRGEVRLNVEEK 439
[Close]
BLAST of GTPase activating protein vs. Ensembl Zebrafish
Match: zgc:56304 (zgc:56304 [Source:ZFIN;Acc:ZDB-GENE-040426-2698])

HSP 1 Score: 110.153 bits (274), Expect = 2.393e-25
Identity = 54/136 (39.71%), Postives = 82/136 (60.29%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQD--LGNFYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + + G        Q EIHK  M+L+ S C   +  +DA  + G  +++QV GE++N+G  +RRFMQ+F+L  +   +  FYV NDIFRY+++ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDYLHRFYGRNSSYVHGGLDSNGKPEEAVYGQAEIHKKVMSLQFSECHTKIRHVDAHATLGDGVVVQVMGELSNSGRPMRRFMQTFVLAPEGSAVNKFYVHNDIFRYEEEVF 138

HSP 2 Score: 85.1149 bits (209), Expect = 3.927e-17
Identity = 45/90 (50.00%), Postives = 59/90 (65.56%), Query Frame = 2 
Query:  932 QSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            + +  YPD HQLFVGNLP ++ E ELK+FF T +G V ++RI    T   G  LPNFGF+VF + + V+ IL  KPI +    RLNVE+K
Sbjct:  354 RRSFRYPDSHQLFVGNLPHDIDEGELKDFFMT-FGNVVEMRIN---TKGVGGKLPNFGFVVFDDSDPVQRILGAKPIMFRGEVRLNVEEK 439
[Close]
BLAST of GTPase activating protein vs. Ensembl Zebrafish
Match: g3bp2 (GTPase activating protein (SH3 domain) binding protein 2 [Source:ZFIN;Acc:ZDB-GENE-070112-1972])

HSP 1 Score: 108.227 bits (269), Expect = 9.448e-25
Identity = 55/136 (40.44%), Postives = 81/136 (59.56%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI--------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   +           GQ EIHK  M+L+ S C   +  +DA  +    +++QV GE++NNG  +R+F+Q+F+L  E  + N FYV NDIFRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRNSSYVHGGLDLNGKLSEAVYGQAEIHKKVMSLQFSECHTKIRHVDAHATLSDGVVVQVMGELSNNGQPMRKFLQTFVLAPEGSVANKFYVHNDIFRYEDEVF 138

HSP 2 Score: 84.7297 bits (208), Expect = 5.831e-17
Identity = 45/90 (50.00%), Postives = 60/90 (66.67%), Query Frame = 2 
Query:  932 QSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            +  + YPD HQLFVGNLP ++ E ELK+FF T +G V ++RI    T + G  +PNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  344 RRVVRYPDSHQLFVGNLPHDIDESELKDFFMT-FGNVVELRIN---TKSTGGKIPNFGFVVFDDSEPVQRILGVKPIMFRGEVRLNVEEK 429
[Close]
BLAST of GTPase activating protein vs. Ensembl Zebrafish
Match: g3bp2 (GTPase activating protein (SH3 domain) binding protein 2 [Source:ZFIN;Acc:ZDB-GENE-070112-1972])

HSP 1 Score: 108.227 bits (269), Expect = 9.448e-25
Identity = 55/136 (40.44%), Postives = 81/136 (59.56%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI--------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   +           GQ EIHK  M+L+ S C   +  +DA  +    +++QV GE++NNG  +R+F+Q+F+L  E  + N FYV NDIFRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRNSSYVHGGLDLNGKLSEAVYGQAEIHKKVMSLQFSECHTKIRHVDAHATLSDGVVVQVMGELSNNGQPMRKFLQTFVLAPEGSVANKFYVHNDIFRYEDEVF 138

HSP 2 Score: 84.7297 bits (208), Expect = 5.831e-17
Identity = 45/90 (50.00%), Postives = 60/90 (66.67%), Query Frame = 2 
Query:  932 QSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            +  + YPD HQLFVGNLP ++ E ELK+FF T +G V ++RI    T + G  +PNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  344 RRVVRYPDSHQLFVGNLPHDIDESELKDFFMT-FGNVVELRIN---TKSTGGKIPNFGFVVFDDSEPVQRILGVKPIMFRGEVRLNVEEK 429
[Close]
BLAST of GTPase activating protein vs. Ensembl Xenopus
Match: g3bp2 (G3BP stress granule assembly factor 2 [Source:NCBI gene;Acc:394887])

HSP 1 Score: 112.464 bits (280), Expect = 5.162e-26
Identity = 57/141 (40.43%), Postives = 84/141 (59.57%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQ---DLGN----FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + A G        Q EIHK  M+L+ S C+  +  +DA  +    +++QV GE++NNG  +R+FMQ+F+L  +   D G+    FYV NDIFRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRNSSYVHGGLDATGKPQEAVYGQAEIHKKVMSLQFSECRTKIRHVDAHATLSDGVVVQVMGELSNNGQPMRKFMQTFVLAPEVMPDTGSVPNKFYVHNDIFRYEDEVF 143

HSP 2 Score: 85.8853 bits (211), Expect = 2.914e-17
Identity = 47/85 (55.29%), Postives = 57/85 (67.06%), Query Frame = 2 
Query:  947 YPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            YPD HQLFVGNLP ++ E ELKEFF + YG V ++RI    T   G  LPNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  334 YPDSHQLFVGNLPHDIDESELKEFFMS-YGNVMELRIN---TKGVGGKLPNFGFVVFDDSEPVQRILLSKPIMFRGEVRLNVEEK 414
[Close]
BLAST of GTPase activating protein vs. Ensembl Xenopus
Match: g3bp2 (G3BP stress granule assembly factor 2 [Source:NCBI gene;Acc:394887])

HSP 1 Score: 112.464 bits (280), Expect = 5.491e-26
Identity = 57/136 (41.91%), Postives = 83/136 (61.03%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + A G        Q EIHK  M+L+ S C+  +  +DA  +    +++QV GE++NNG  +R+FMQ+F+L  E  + N FYV NDIFRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRNSSYVHGGLDATGKPQEAVYGQAEIHKKVMSLQFSECRTKIRHVDAHATLSDGVVVQVMGELSNNGQPMRKFMQTFVLAPEGSVPNKFYVHNDIFRYEDEVF 138

HSP 2 Score: 85.8853 bits (211), Expect = 2.987e-17
Identity = 47/85 (55.29%), Postives = 57/85 (67.06%), Query Frame = 2 
Query:  947 YPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            YPD HQLFVGNLP ++ E ELKEFF + YG V ++RI    T   G  LPNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  329 YPDSHQLFVGNLPHDIDESELKEFFMS-YGNVMELRIN---TKGVGGKLPNFGFVVFDDSEPVQRILLSKPIMFRGEVRLNVEEK 409
[Close]
BLAST of GTPase activating protein vs. Ensembl Xenopus
Match: g3bp2 (G3BP stress granule assembly factor 2 [Source:NCBI gene;Acc:394887])

HSP 1 Score: 112.079 bits (279), Expect = 7.041e-26
Identity = 58/147 (39.46%), Postives = 86/147 (58.50%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQ---DLGN----FYVLNDIFRYQDQTFKVEDVE 499
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + A G        Q EIHK  M+L+ S C+  +  +DA  +    +++QV GE++NNG  +R+FMQ+F+L  +   D G+    FYV NDIFRY+D+ F   + E
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRNSSYVHGGLDATGKPQEAVYGQAEIHKKVMSLQFSECRTKIRHVDAHATLSDGVVVQVMGELSNNGQPMRKFMQTFVLAPEVMPDTGSVPNKFYVHNDIFRYEDEVFGDSEAE 149

HSP 2 Score: 85.8853 bits (211), Expect = 2.501e-17
Identity = 47/85 (55.29%), Postives = 57/85 (67.06%), Query Frame = 2 
Query:  947 YPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            YPD HQLFVGNLP ++ E ELKEFF + YG V ++RI    T   G  LPNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  323 YPDSHQLFVGNLPHDIDESELKEFFMS-YGNVMELRIN---TKGVGGKLPNFGFVVFDDSEPVQRILLSKPIMFRGEVRLNVEEK 403
[Close]
BLAST of GTPase activating protein vs. Ensembl Xenopus
Match: fhod1 (formin homology 2 domain containing 1 [Source:Xenbase;Acc:XB-GENE-948719])

HSP 1 Score: 109.383 bits (272), Expect = 1.658e-25
Identity = 57/144 (39.58%), Postives = 84/144 (58.33%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI--------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTFKVEDVEEP 505
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V   +           GQ +IHK  M+L   +C+  +  +DA  +    +++QV GE++NN   +RRFMQ+F+L  E  + N FYV NDIFRYQD+ F   D E P
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNQAPDFLHRFYGKSSSYVHGGLDTNGKPAEAVYGQTDIHKKVMSLNFKDCRTKIRHVDAHATLNDGVVVQVMGELSNNRQPMRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGDSDTEPP 146

HSP 2 Score: 85.5001 bits (210), Expect = 1.883e-17
Identity = 45/85 (52.94%), Postives = 59/85 (69.41%), Query Frame = 2 
Query:  947 YPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            YPD HQLFVGNLP ++ + ELKEFF T YG V ++RI      N G  LPNFGF+VF + + V++IL ++PI +    RLNVE+K
Sbjct:  239 YPDSHQLFVGNLPHDVDKSELKEFFQT-YGNVVELRI------NSGGKLPNFGFVVFDDADPVQKILGNRPIMFRGDVRLNVEEK 316
[Close]
BLAST of GTPase activating protein vs. Ensembl Xenopus
Match: fhod1 (formin homology 2 domain containing 1 [Source:Xenbase;Acc:XB-GENE-948719])

HSP 1 Score: 108.612 bits (270), Expect = 3.808e-25
Identity = 57/144 (39.58%), Postives = 84/144 (58.33%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI--------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTFKVEDVEEP 505
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V   +           GQ +IHK  M+L   +C+  +  +DA  +    +++QV GE++NN   +RRFMQ+F+L  E  + N FYV NDIFRYQD+ F   D E P
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNQAPDFLHRFYGKSSSYVHGGLDTNGKPAEAVYGQTDIHKKVMSLNFKDCRTKIRHVDAHATLNDGVVVQVMGELSNNRQPMRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGDSDTEPP 146

HSP 2 Score: 77.411 bits (189), Expect = 1.038e-14
Identity = 39/74 (52.70%), Postives = 52/74 (70.27%), Query Frame = 2 
Query:  947 YPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYY 1168
            YPD HQLFVGNLP ++ + ELKEFF T YG V ++RI      N G  LPNFGF+VF + + V++IL ++ IY+
Sbjct:  331 YPDSHQLFVGNLPHDVDKSELKEFFQT-YGNVVELRI------NSGGKLPNFGFVVFDDADPVQKILGNRVIYF 397
[Close]
BLAST of GTPase activating protein vs. Ensembl Mouse
Match: G3bp1 (GTPase activating protein (SH3 domain) binding protein 1 [Source:MGI Symbol;Acc:MGI:1351465])

HSP 1 Score: 102.064 bits (253), Expect = 9.583e-23
Identity = 55/138 (39.86%), Postives = 80/138 (57.97%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVR----------DDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++N+ P  LHRFY + S+             D +Y  GQ EIH+  M+   +NC   +  +DA  +    +++QV G ++NN   LRRFMQ+F+L  E  + N FYV NDIFRYQD+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYAHGGLDSNGKPADAVY--GQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF 138

HSP 2 Score: 85.8853 bits (211), Expect = 1.886e-17
Identity = 47/108 (43.52%), Postives = 70/108 (64.81%), Query Frame = 2 
Query:  923 VKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYY-SSHRLNVEQKMGNSRATYKAGRR*N 1243
            V+P+  + +PD HQLF+GNLP  + + ELK+FF   +G V ++RI      N G  LPNFGF+VF + E V+++L ++PI +  + RLNVE+K   +RA  +  RR N
Sbjct:  326 VEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQN-FGNVVELRI------NSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGAVRLNVEEK--KTRAAREGDRRDN 424
[Close]
BLAST of GTPase activating protein vs. Ensembl Mouse
Match: G3bp2 (GTPase activating protein (SH3 domain) binding protein 2 [Source:MGI Symbol;Acc:MGI:2442040])

HSP 1 Score: 96.6709 bits (239), Expect = 5.801e-21
Identity = 51/136 (37.50%), Postives = 79/136 (58.09%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + A G        Q++IH   ++L  S C   +  +DA  +    +++QV G ++N+G   R+FMQ+F+L  E  + N FYV ND+FRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVF 138

HSP 2 Score: 83.9593 bits (206), Expect = 9.827e-17
Identity = 46/87 (52.87%), Postives = 58/87 (66.67%), Query Frame = 2 
Query:  941 LNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            + YPD HQLFVGNLP ++ E ELKEFF + +G V ++RI    T   G  LPNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  325 IRYPDSHQLFVGNLPHDIDENELKEFFMS-FGNVVELRIN---TKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEK 407
[Close]
BLAST of GTPase activating protein vs. Ensembl Mouse
Match: G3bp2 (GTPase activating protein (SH3 domain) binding protein 2 [Source:MGI Symbol;Acc:MGI:2442040])

HSP 1 Score: 96.6709 bits (239), Expect = 5.801e-21
Identity = 51/136 (37.50%), Postives = 79/136 (58.09%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + A G        Q++IH   ++L  S C   +  +DA  +    +++QV G ++N+G   R+FMQ+F+L  E  + N FYV ND+FRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVF 138

HSP 2 Score: 83.9593 bits (206), Expect = 9.827e-17
Identity = 46/87 (52.87%), Postives = 58/87 (66.67%), Query Frame = 2 
Query:  941 LNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            + YPD HQLFVGNLP ++ E ELKEFF + +G V ++RI    T   G  LPNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  325 IRYPDSHQLFVGNLPHDIDENELKEFFMS-FGNVVELRIN---TKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEK 407
[Close]
BLAST of GTPase activating protein vs. Ensembl Mouse
Match: G3bp2 (GTPase activating protein (SH3 domain) binding protein 2 [Source:MGI Symbol;Acc:MGI:2442040])

HSP 1 Score: 96.6709 bits (239), Expect = 5.801e-21
Identity = 51/136 (37.50%), Postives = 79/136 (58.09%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + A G        Q++IH   ++L  S C   +  +DA  +    +++QV G ++N+G   R+FMQ+F+L  E  + N FYV ND+FRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVF 138

HSP 2 Score: 83.9593 bits (206), Expect = 9.827e-17
Identity = 46/87 (52.87%), Postives = 58/87 (66.67%), Query Frame = 2 
Query:  941 LNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            + YPD HQLFVGNLP ++ E ELKEFF + +G V ++RI    T   G  LPNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  325 IRYPDSHQLFVGNLPHDIDENELKEFFMS-FGNVVELRIN---TKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEK 407
[Close]
BLAST of GTPase activating protein vs. Ensembl Mouse
Match: G3bp2 (GTPase activating protein (SH3 domain) binding protein 2 [Source:MGI Symbol;Acc:MGI:2442040])

HSP 1 Score: 96.2857 bits (238), Expect = 7.428e-21
Identity = 51/136 (37.50%), Postives = 79/136 (58.09%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + A G        Q++IH   ++L  S C   +  +DA  +    +++QV G ++N+G   R+FMQ+F+L  E  + N FYV ND+FRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVF 138

HSP 2 Score: 83.5741 bits (205), Expect = 9.292e-17
Identity = 46/87 (52.87%), Postives = 58/87 (66.67%), Query Frame = 2 
Query:  941 LNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            + YPD HQLFVGNLP ++ E ELKEFF + +G V ++RI    T   G  LPNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  292 IRYPDSHQLFVGNLPHDIDENELKEFFMS-FGNVVELRIN---TKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEK 374
[Close]
BLAST of GTPase activating protein vs. UniProt/SwissProt
Match: sp|O94260|G3BP_SCHPO (Putative G3BP-like protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=nxt3 PE=1 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 2.148e-25
Identity = 108/392 (27.55%), Postives = 169/392 (43.11%), Query Frame = 2 
Query:  140 FVLQFYTIMNKQPGSLHRFYKEESTLVRDD-----IYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVE----EPPMVEHESKNEDIHGEINSWNEIKNC-EINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKDISIEIPVE--IDTT---------------QD------------IGQKMEELTIKEKSWAAIINPMSNRPSXXXXXXXXXXXXXXXIQQKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQK 1198
            FV ++YT +NK+P  LH FY ++STL+  D         GQ EIH   ++L+  NCK ++ ++D++ S    I+IQV GE++N G   R+F Q+F L EQ  G ++VLNDIFR     F  EDVE     P  VE E K+      +N     ++      E   Q P   E+   +   I+ N  +     ++ +P E  I  T               QD            IG     +    KSWA +I    N P   +        +      K +N+     D+ +Q        P +  N   E  +FV N+P   ++  LK   S  +G VK +   + + +          ++ F NHE V+  L  K +  ++  LN+E++
Sbjct:   22 FVQEYYTYLNKEPNRLHCFYTKKSTLIHGDEGESISLCHGQQEIHNKILDLDFQNCKVLISNVDSLASSNGGIVIQVLGEMSNKGKLSRKFAQTFFLAEQPNG-YFVLNDIFR-----FLREDVEEEEESPDAVEKEKKDVASEPYVNGVQSQEHLPSAKEEGHYQDPAATENNFATAALIS-NETDSLNQATLAVPEEPVIQVTEASVPSFVSQQENQLQDEALTSNSKNADAIGASDANVATAPKSWADLI--ARNHPDVKSQASVSSTASTTGQTVKGVNA-----DQTQQ-----PTAPYTQSNELLETSVFVKNIPPETSDVSLKSAMSI-FGPVKAIEFARRKGT---------AYVDFVNHECVQLALNKKTLQINNATLNIEER 384
[Close]
BLAST of GTPase activating protein vs. UniProt/SwissProt
Match: sp|Q5RB87|G3BP1_PONAB (Ras GTPase-activating protein-binding protein 1 OS=Pongo abelii OX=9601 GN=G3BP1 PE=2 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 2.034e-22
Identity = 56/138 (40.58%), Postives = 81/138 (58.70%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVR----------DDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V           D +Y  GQ EIH+  M+   +NC   +  +DA  +    +++QV G ++NN   LRRFMQ+F+L  E  + N FYV NDIFRYQD+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVY--GQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF 138

HSP 2 Score: 87.8113 bits (216), Expect = 3.344e-17
Identity = 47/108 (43.52%), Postives = 70/108 (64.81%), Query Frame = 2 
Query:  923 VKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQKMGNSRATYKAGRR*N 1243
            ++P+  + +PD HQLF+GNLP  + + ELK+FF + YG V ++RI      N G  LPNFGF+VF + E V+++L ++PI +    RLNVE+K   +RA  +  RR N
Sbjct:  328 IEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQS-YGNVVELRI------NSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEK--KTRAAREGDRRDN 426
[Close]
BLAST of GTPase activating protein vs. UniProt/SwissProt
Match: sp|Q13283|G3BP1_HUMAN (Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 2.053e-22
Identity = 56/138 (40.58%), Postives = 81/138 (58.70%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVR----------DDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V           D +Y  GQ EIH+  M+   +NC   +  +DA  +    +++QV G ++NN   LRRFMQ+F+L  E  + N FYV NDIFRYQD+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVY--GQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF 138

HSP 2 Score: 87.8113 bits (216), Expect = 3.375e-17
Identity = 47/108 (43.52%), Postives = 70/108 (64.81%), Query Frame = 2 
Query:  923 VKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQKMGNSRATYKAGRR*N 1243
            ++P+  + +PD HQLF+GNLP  + + ELK+FF + YG V ++RI      N G  LPNFGF+VF + E V+++L ++PI +    RLNVE+K   +RA  +  RR N
Sbjct:  328 IEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQS-YGNVVELRI------NSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEK--KTRAAREGDRRDN 426
[Close]
BLAST of GTPase activating protein vs. UniProt/SwissProt
Match: sp|Q32LC7|G3BP1_BOVIN (Ras GTPase-activating protein-binding protein 1 OS=Bos taurus OX=9913 GN=G3BP1 PE=2 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 2.174e-22
Identity = 56/138 (40.58%), Postives = 81/138 (58.70%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVR----------DDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V           D +Y  GQ EIH+  M+   +NC   +  +DA  +    +++QV G ++NN   LRRFMQ+F+L  E  + N FYV NDIFRYQD+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVY--GQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF 138

HSP 2 Score: 87.4261 bits (215), Expect = 4.322e-17
Identity = 48/108 (44.44%), Postives = 69/108 (63.89%), Query Frame = 2 
Query:  923 VKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQKMGNSRATYKAGRR*N 1243
            V+P+  + +PD HQLF+GNLP  + + ELK+FF   YG V ++RI      N G  LPNFGF+VF + E V+++L ++PI +    RLNVE+K   +RA  +  RR N
Sbjct:  327 VEPRRIVRHPDSHQLFIGNLPHEVDKSELKDFFQN-YGNVVELRI------NSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEK--KTRAAREGDRRDN 425
[Close]
BLAST of GTPase activating protein vs. UniProt/SwissProt
Match: sp|P97855|G3BP1_MOUSE (Ras GTPase-activating protein-binding protein 1 OS=Mus musculus OX=10090 GN=G3bp1 PE=1 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 6.704e-22
Identity = 55/138 (39.86%), Postives = 80/138 (57.97%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVR----------DDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++N+ P  LHRFY + S+             D +Y  GQ EIH+  M+   +NC   +  +DA  +    +++QV G ++NN   LRRFMQ+F+L  E  + N FYV NDIFRYQD+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYAHGGLDSNGKPADAVY--GQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF 138

HSP 2 Score: 85.8853 bits (211), Expect = 1.319e-16
Identity = 47/108 (43.52%), Postives = 70/108 (64.81%), Query Frame = 2 
Query:  923 VKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYY-SSHRLNVEQKMGNSRATYKAGRR*N 1243
            V+P+  + +PD HQLF+GNLP  + + ELK+FF   +G V ++RI      N G  LPNFGF+VF + E V+++L ++PI +  + RLNVE+K   +RA  +  RR N
Sbjct:  326 VEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQN-FGNVVELRI------NSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGAVRLNVEEK--KTRAAREGDRRDN 424
[Close]
BLAST of GTPase activating protein vs. TrEMBL
Match: A4V6M6 (GTPase activating protein OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0
Identity = 350/391 (89.51%), Postives = 376/391 (96.16%), Query Frame = 2 
Query:   68 MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIHGEINSWNEI-KNCEINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKDISIEIPVEIDTTQDIGQKMEELTIKEKSWAAIINPMSNRPSXXXXXXXXXXXXXXXIQQKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKMGNSRATYKAGRR 1237
            MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNK PGSLHRFYKEESTL+RD+++AQGQ+EIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEE P+VEHESKNE+IHGEINSWNE+ +NCE+NNE + QSPQLIEHEEGSEEFINY IMNEEK++S EIPVEID+ QDIGQKMEE+ IKEKSWAAIINPMS+RPSKPTAPVAPQPQTAKPIQQKQINSNGDN++KRK RFNN +VK QSTLNYPDEHQLFVGNLPQNMTE+ELK+FFS KYG VKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILK+KPIYYS+HRLNVEQKMG+SR ++KAGRR
Sbjct:    1 MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNKHPGSLHRFYKEESTLIRDEVHAQGQNEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEAPIVEHESKNEEIHGEINSWNEMSRNCELNNEQIPQSPQLIEHEEGSEEFINYKIMNEEKELSSEIPVEIDSQQDIGQKMEEMNIKEKSWAAIINPMSSRPSKPTAPVAPQPQTAKPIQQKQINSNGDNMEKRKPRFNNGNVKTQSTLNYPDEHQLFVGNLPQNMTEDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIYYSAHRLNVEQKMGSSRGSHKAGRR 391
[Close]
BLAST of GTPase activating protein vs. TrEMBL
Match: D5JG82 (GTPase activating protein OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 660.218 bits (1702), Expect = 0.000e+0
Identity = 337/391 (86.19%), Postives = 362/391 (92.58%), Query Frame = 2 
Query:   68 MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIHGEINSWNEI-KNCEINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKDISIEIPVEIDTTQDIGQKMEELTIKEKSWAAIINPMSNRPSXXXXXXXXXXXXXXXIQQKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKMGNSRATYKAGRR 1237
            MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNK PGSLHRFYKEESTL+RD+++AQGQ+EIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEE P+VEHESKNE+IHGEINSWNE+ +NCE+NNE + QSPQLIEHEEG               +S EIPVEID+ QDIGQKMEE+ IKEKSWAAIINPMS+RPSKPTAPVAPQPQTAKPIQQKQINSNGDN++KRK RFNN +VK QSTLNYPDEHQLFVGNLPQNMTE+ELK+FFS KYG VKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILK+KPIYYS+HRLNVEQKMG+SR ++KAGRR
Sbjct:    1 MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNKHPGSLHRFYKEESTLIRDEVHAQGQNEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEAPIVEHESKNEEIHGEINSWNEMSRNCELNNEQIPQSPQLIEHEEGK--------------LSSEIPVEIDSQQDIGQKMEEMNIKEKSWAAIINPMSSRPSKPTAPVAPQPQTAKPIQQKQINSNGDNMEKRKPRFNNGNVKTQSTLNYPDEHQLFVGNLPQNMTEDELKDFFSEKYGPVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKNKPIYYSAHRLNVEQKMGSSRGSHKAGRR 377
[Close]
BLAST of GTPase activating protein vs. TrEMBL
Match: K1QEJ0 (Ras GTPase-activating protein-binding protein 2 OS=Crassostrea gigas OX=29159 GN=CGI_10005086 PE=4 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 4.657e-45
Identity = 138/418 (33.01%), Postives = 207/418 (49.52%), Query Frame = 2 
Query:   95 VVNMDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTF----KVEDVEEPPMVEHESKNEDIHGEINSWN---------EIKNCEINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKD-ISIEIPVEIDTTQDIGQKMEELTIKEKSWAAIINPMS-----NRPSXXXXXXXXXXXXXXXIQQKQ--------------------INSNGDN--IDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSS-HRLNVEQK 1198
            V+ M+      V +EFV Q+YT++N+ P  LHRFY   S+ V   +   G        Q EIHK  M+L   +C A +  +D+  + G ++++QVTGE++NNG  +RRFMQ+F+L  Q    +YV NDIFRYQD+ F     +E+ EE   VE+ + N ++   +              + N   + E    SP     EE  +E +      EEK+ I  E+PVE +      +       K  SWAA+ +  +     ++PS   +P   +       +Q Q                    ++++ D+  +D +  R             +PD HQLFVGNLPQN+ E EL+ FF  KYG V +VRI     S  GK +PNFGF+VF +   V EIL+ +P+ ++  HRLNVE+K
Sbjct:   26 VMVMETPSPQCVGREFVRQYYTLLNEVPLHLHRFYSHNSSFVHGGVEKPGEEQPPVVGQAEIHKKIMSLNFRDCHAKIRQVDSQATVGNAVVVQVTGELSNNGQPMRRFMQTFVLAPQSPKKYYVHNDIFRYQDEVFHDDSDIENQEEDSDVENMATNPNVQESMQDPGVQNFYEPPPSLSNGTSHLEDRVDSPSQKSAEEDKDEGLEPEPAYEEKEMIDEEVPVEQEPEAQEEEPQNAGEPKPFSWAALASKNTPSGQVSQPSTMPSPPQQKSSGGPGFRQDQGTGPQPQRTQRSRERRERDRLSASKDDGEVDAQSNRRLGGGGGGGPPSRFPDSHQLFVGNLPQNVMESELRVFFE-KYGNVVEVRINAK--SVPGK-VPNFGFVVFDSPTPVGEILRMRPLLFNGDHRLNVEEK 439
[Close]
BLAST of GTPase activating protein vs. TrEMBL
Match: A0A4W3J766 (Uncharacterized protein OS=Callorhinchus milii OX=7868 GN=g3bp2 PE=4 SV=1)

HSP 1 Score: 166.777 bits (421), Expect = 3.553e-42
Identity = 133/405 (32.84%), Postives = 199/405 (49.14%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIHGEI-----NSWNEIKNCEINNEP-VSQSPQLIEHEEGSE-EFINYNIMNEEKDISIEIPVEIDTTQDIGQKMEELTIKEKSWAAIIN---PMSNRPSXXXXXXXXXXXXXXXIQ-----QKQINSNGDNIDKRKQRFNNVSVKPQST--------------LNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   + A G        Q EIHK  M+L+ S+C   +  +DA  +    +++QV GE++NNG  +R+FMQ+F+L  E  + N FYV NDIFRYQD+ F   D E    +E   K E ++  +     +S+N ++       P +   P+    E  SE E +  ++   E+      PVE      + Q  E    K  SWA++ +   P S   S    P       A   +     + Q         + ++R   V   P++               + YPD HQLFVGNLP ++ E ELK+FF + +G V ++RI    T + G  LPNFGF+VF + + V+ IL  KP+ +    RLNVE+K
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRTSSYVHGGLNANGKPADAVYGQAEIHKKVMSLQFSDCHTKIRHVDAHATLSDGVVVQVMGELSNNGQPMRKFMQTFVLAPEGSVPNKFYVHNDIFRYQDEVFD-SDAE----LEEGMKFEQLYVTLASLFCSSFNGVEEALEETAPELEPDPEPKTEEIKSEPELVEKSVEELEEKAPSPAPVE-----PVSQPQE--PPKAFSWASVTSKNLPPSGTVSSSGIPPHVVKAPASQPRAECKTEPQAQPPRPRDQRPRERIGLVPRGPRTGRGENEQNEVENRRIIRYPDSHQLFVGNLPHDIDENELKDFFMS-FGNVVELRIN---TKSSGGKLPNFGFVVFDDPDPVQRILNAKPVMFRGEVRLNVEEK 391
[Close]
BLAST of GTPase activating protein vs. TrEMBL
Match: G3PXB8 (GTPase activating protein (SH3 domain) binding protein 1 OS=Gasterosteus aculeatus OX=69293 PE=4 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 6.937e-42
Identity = 134/439 (30.52%), Postives = 198/439 (45.10%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI--------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDI----------HGEINSWNEIKNCEINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKDISIEIPVEIDTTQDIGQKMEELTIKEK------------------SWAAIIN---------PMSNRPSXXXXXXXXXXXXXXXIQQKQINSNGDNIDKRKQRFNNVSVKPQS-------------TLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQKMGNSRATYKAGRR 1237
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V   +           GQ EIHK  M L    C   +  +DA  +  + +++QV GE++NN   +R+FMQ+F+L  E  + N FYV ND+FRYQD+ F   D E P   E E + EDI          H E  S+     C   +EP           E   E     +     ++  E   E + + D  QK                           SWA++ +         P+S  P          P  A+   + Q  +     D+R +   +   +P S              + YPD  QLFVGN+P ++ + ELKEFF  +YGTV ++RI      N G  LPNFGF+VF + E V++IL ++PI +    RLNVE+K   +R+  +  RR
Sbjct:    3 MEKPSAQLVGREFVRQYYTLLNQAPDYLHRFYGKNSSYVHGGLDNNGKPVEAVYGQSEIHKRVMALSFRECHTKIRHVDAHATLNEGVVVQVMGELSNNMQPMRKFMQTFVLAPEGTVANKFYVHNDVFRYQDEVFSDSDSEAP--EESEDEVEDIEERVPSPDIAHEESASFYAPTAC---SEPAIPGDAAAASPEPEPEKAPAVV-----ELKPETQAETNASDDQKQKSTTPAAATPAPASAEPAPAAPEENRPFSWASVTSKNLPPSGAVPVSGIPPHVVKAPPTAPPRAEVKSESQTAAQRPQRDQRPREPVHRGPRPVSVREGEQGEQESRRAVRYPDAQQLFVGNVPHDVDKTELKEFFE-QYGTVLELRI------NSGGKLPNFGFVVFDDSEPVQKILSNRPIKFRGDVRLNVEEK--KTRSAREGDRR 422
[Close]
BLAST of GTPase activating protein vs. Ensembl Cavefish
Match: zgc:56304 (G3BP stress granule assembly factor 2 [Source:NCBI gene;Acc:103039367])

HSP 1 Score: 110.538 bits (275), Expect = 1.213e-25
Identity = 55/142 (38.73%), Postives = 83/142 (58.45%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQD--LGNFYVLNDIFRYQDQTFKVEDVE 499
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   +   G        Q EIHK  M+L+ S C   +  +DA  + G  +++QV GE++N+G  +RRFMQ+F+L  +   +  FYV NDIFRY+++ F   + E
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDYLHRFYGRNSSYVHGGLDGSGKPEEAVYGQAEIHKKVMSLQFSECHTKIRHVDAHATLGDGVVVQVMGELSNSGRPMRRFMQTFVLAPEGSAVNKFYVHNDIFRYEEEVFGDSEAE 144

HSP 2 Score: 86.2705 bits (212), Expect = 1.295e-17
Identity = 47/93 (50.54%), Postives = 61/93 (65.59%), Query Frame = 2 
Query:  923 VKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            V+ +  + YPD HQLFVGNLP ++ E ELK+FF T +G V ++RI    T   G  LPNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  314 VEGRRAVRYPDSHQLFVGNLPHDIDEGELKDFFMT-FGNVVEMRIN---TKGVGGKLPNFGFVVFDDSEPVQRILGAKPIMFRGEVRLNVEEK 402
[Close]
BLAST of GTPase activating protein vs. Ensembl Cavefish
Match: zgc:56304 (G3BP stress granule assembly factor 2 [Source:NCBI gene;Acc:103039367])

HSP 1 Score: 110.923 bits (276), Expect = 1.291e-25
Identity = 54/136 (39.71%), Postives = 81/136 (59.56%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQD--LGNFYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   +   G        Q EIHK  M+L+ S C   +  +DA  + G  +++QV GE++N+G  +RRFMQ+F+L  +   +  FYV NDIFRY+++ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDYLHRFYGRNSSYVHGGLDGSGKPEEAVYGQAEIHKKVMSLQFSECHTKIRHVDAHATLGDGVVVQVMGELSNSGRPMRRFMQTFVLAPEGSAVNKFYVHNDIFRYEEEVF 138

HSP 2 Score: 85.8853 bits (211), Expect = 1.669e-17
Identity = 47/93 (50.54%), Postives = 61/93 (65.59%), Query Frame = 2 
Query:  923 VKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQK 1198
            V+ +  + YPD HQLFVGNLP ++ E ELK+FF T +G V ++RI    T   G  LPNFGF+VF + E V+ IL  KPI +    RLNVE+K
Sbjct:  353 VEGRRAVRYPDSHQLFVGNLPHDIDEGELKDFFMT-FGNVVEMRIN---TKGVGGKLPNFGFVVFDDSEPVQRILGAKPIMFRGEVRLNVEEK 441
[Close]
BLAST of GTPase activating protein vs. Ensembl Cavefish
Match: g3bp1 (G3BP stress granule assembly factor 1 [Source:NCBI gene;Acc:103026994])

HSP 1 Score: 107.842 bits (268), Expect = 7.929e-25
Identity = 57/144 (39.58%), Postives = 83/144 (57.64%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI--------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTFKVEDVEEP 505
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V   +           GQ EIHK  M L   +C   +  +DA  +  + +++QV GE++NN   +R+FMQ+F+L  E  + N FYV NDIFRYQD+ F   D E P
Sbjct:    3 MEKPSAQLVGREFVRQYYTLLNQAPDYLHRFYGKNSSYVHGGLDTNGKPAEAVYGQSEIHKKVMALSFRDCHTKIRHVDAHATLNEGVVVQVMGELSNNMQPMRKFMQTFVLAPEGTVANKFYVHNDIFRYQDEVFGDSDSEPP 146

HSP 2 Score: 82.8037 bits (203), Expect = 1.401e-16
Identity = 47/103 (45.63%), Postives = 66/103 (64.08%), Query Frame = 2 
Query:  932 QSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQKMGNSRATYKAGRR 1237
            +  + YPD  QLFVGN+P ++ + ELKEFF  +YGTV ++RI      N G  LPNFGF+VF + E V++IL ++PI      RLNVE+K   +R+  +  RR
Sbjct:  307 RRVVRYPDSQQLFVGNVPHDVDKAELKEFFE-QYGTVLELRI------NSGGKLPNFGFVVFDDSEPVQKILSNRPIKLRGDVRLNVEEK--KTRSAREGDRR 400
[Close]
BLAST of GTPase activating protein vs. Ensembl Cavefish
Match: g3bp1 (G3BP stress granule assembly factor 1 [Source:NCBI gene;Acc:103026994])

HSP 1 Score: 104.375 bits (259), Expect = 1.558e-23
Identity = 54/136 (39.71%), Postives = 80/136 (58.82%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI--------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V   +           GQ EIHK  M L   +C   +  +DA  +  + +++QV GE++NN   +R+FMQ+F+L  E  + N FYV NDIFRYQD+ F
Sbjct:    3 MEKPSAQLVGREFVRQYYTLLNQAPDYLHRFYGKNSSYVHGGLDTNGKPAEAVYGQSEIHKKVMALSFRDCHTKIRHVDAHATLNEGVVVQVMGELSNNMQPMRKFMQTFVLAPEGTVANKFYVHNDIFRYQDEVF 138

HSP 2 Score: 82.8037 bits (203), Expect = 1.581e-16
Identity = 47/100 (47.00%), Postives = 65/100 (65.00%), Query Frame = 2 
Query:  941 LNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQKMGNSRATYKAGRR 1237
            + YPD  QLFVGN+P ++ + ELKEFF  +YGTV ++RI      N G  LPNFGF+VF + E V++IL ++PI      RLNVE+K   +R+  +  RR
Sbjct:  338 VRYPDSQQLFVGNVPHDVDKAELKEFFE-QYGTVLELRI------NSGGKLPNFGFVVFDDSEPVQKILSNRPIKLRGDVRLNVEEK--KTRSAREGDRR 428
[Close]
BLAST of GTPase activating protein vs. Ensembl Cavefish
Match: nxt2 (nuclear transport factor 2 like export factor 2 [Source:NCBI gene;Acc:103035937])

HSP 1 Score: 50.0618 bits (118), Expect = 4.381e-7
Identity = 43/144 (29.86%), Postives = 71/144 (49.31%), Query Frame = 2 
Query:   68 MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAV---KSHGKSILIQVT-GEIANNGCDLRRFMQSFLLVEQDLGN-----FYVLNDIFRYQD 472
            M +  D+ T V    D     S+EFV  +Y  M+K+  +L R Y +++TLV +     GQ  + +++ +L  S  +   L    V    + G++ L+ VT G +  +G   R F Q+FLL  Q   N     + + +D FR+QD
Sbjct:    1 MASTVDFRTHV----DQSCRYSEEFVNIYYDCMDKKRRNLTRLYLDKATLVWNGNAFSGQDSLGEFFESLPSSEFQVHTLDCQPVHEQATQGQTTLLVVTAGLVKFDGNKQRYFNQNFLLTAQPSPNSDQPVWKIASDCFRFQD 140
[Close]
BLAST of GTPase activating protein vs. Ensembl Sea Lamprey
Match: g3bp2 (GTPase activating protein (SH3 domain) binding protein 2 [Source:ZFIN;Acc:ZDB-GENE-070112-1972])

HSP 1 Score: 112.464 bits (280), Expect = 6.437e-29
Identity = 59/136 (43.38%), Postives = 83/136 (61.03%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQ--------HEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M+R     V +EFV Q+YT++N+ P  LHRFY + ST V   + A GQ         EIHK  M+L   +C   +  +DA+ S G  +++QV GE++N G  +RRFMQ+F+L  E  + N FYV ND+FRYQD+ F
Sbjct:    3 MERPSPQLVGREFVRQYYTLLNQAPDYLHRFYGKNSTYVHGGLDANGQPAEAVIGQAEIHKKVMSLGFRDCHTKIRHVDALASLGDGVVVQVMGELSNAGQPMRRFMQTFVLAPEGSVPNKFYVHNDMFRYQDEVF 138
[Close]
BLAST of GTPase activating protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005655.1 (pep scaffold:Pmarinus_7.0:GL487992:4034:7677:-1 gene:ENSPMAG00000005131.1 transcript:ENSPMAT00000005655.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.1965 bits (217), Expect = 5.030e-21
Identity = 48/134 (35.82%), Postives = 76/134 (56.72%), Query Frame = 2 
Query:  131 SQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTFKVEDVEE 502
            S + V   + +     GSL RFY ++ST V   + A G        Q EIH   ++L   +C+  + ++D+  + G ++++QV GE++N G  +RRF+Q+F+L  E  + N F+V NDIFRYQD+ F   D  E
Sbjct:   12 SDDLVTARFILSCVVGGSLRRFYGKDSTFVHGGVDANGKPSEPVVGQMEIHARIVSLAFRDCRTKIRAVDSQATMGGAVVVQVLGELSNAGGAMRRFLQTFILAPEGSVQNKFFVQNDIFRYQDEVFTDSDHSE 145
[Close]
BLAST of GTPase activating protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009806.1 (pep scaffold:Pmarinus_7.0:GL479354:9188:12030:-1 gene:ENSPMAG00000008859.1 transcript:ENSPMAT00000009806.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.447 bits (119), Expect = 4.619e-7
Identity = 27/75 (36.00%), Postives = 42/75 (56.00%), Query Frame = 2 
Query:  929 PQSTL--NYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEIL 1147
            PQS +    PD +++FVG  P+++T E+L+ FF  ++G V DV I         KP  +FGF+ F N  V + + 
Sbjct:  185 PQSKMYPTDPDRNRIFVGRCPEDITPEDLRSFFG-QFGDVTDVYIP--------KPFRSFGFVTFANEHVAQSLC 250
[Close]
BLAST of GTPase activating protein vs. Ensembl Sea Lamprey
Match: HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0 [Source:HGNC Symbol;Acc:HGNC:5030])

HSP 1 Score: 48.1358 bits (113), Expect = 3.084e-6
Identity = 27/94 (28.72%), Postives = 53/94 (56.38%), Query Frame = 2 
Query:  920 SVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKM 1201
            S+KP + L      ++FVG +  N  E+ L+++FS +YG V+ V + + R S + +    FGF+ F +H+ V++++  K    + H+  V + +
Sbjct:  114 SLKPGAHLKVK---KIFVGGIKDNTDEDHLRDYFS-EYGMVESVDVMEDRQSGKKR---GFGFVTFSDHDAVDKVVVQKYHTINGHKAEVRKAL 200
[Close]
BLAST of GTPase activating protein vs. Ensembl Sea Lamprey
Match: HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0 [Source:HGNC Symbol;Acc:HGNC:5030])

HSP 1 Score: 45.4394 bits (106), Expect = 9.509e-6
Identity = 24/94 (25.53%), Postives = 51/94 (54.26%), Query Frame = 2 
Query:  920 SVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKM 1201
            S+KP + L      ++FVG +  +  E+ L+E+F   YG V+   + + R++ + +    FGF+ F +H+ V++++  K    + H+  V + +
Sbjct:   90 SLKPGAHLKVK---KIFVGGIRDDTDEQHLREYFQV-YGDVEAAEVMEDRSTGKKR---GFGFVTFSDHDTVDKVIVQKYHTINGHKAEVRKAL 176
[Close]
BLAST of GTPase activating protein vs. Ensembl Yeast
Match: BRE5 (Ubiquitin protease cofactor; forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A [Source:SGD;Acc:S000005334])

HSP 1 Score: 51.9878 bits (123), Expect = 1.295e-7
Identity = 38/136 (27.94%), Postives = 63/136 (46.32%), Query Frame = 2 
Query:  140 FVLQFYTIMNKQPGSLHRFYKEESTLV-----------RDDIY----AQGQHEIHKYYMNLELSNCKAVVLSLDAV----KSH-GKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGN-FYVLNDIFRYQDQTFK 484
            F+  +Y  M   P  L  FY   + L            +DD+       G+  I+K++   + +  +++ L LD +      H  KSILI  TGE+   G  + +F Q+F+L+    G+ F + NDI R+   +FK
Sbjct:   12 FLQNYYERMRTDPSKLAYFYASTAELTHTNYQSKSTNEKDDVLPTVKVTGRENINKFFSRND-AKVRSLKLKLDTIDFQYTGHLHKSILIMATGEMFWTGTPVYKFCQTFILLPSSNGSTFDITNDIIRFISNSFK 146
[Close]
BLAST of GTPase activating protein vs. Ensembl Yeast
Match: HRP1 (Subunit of cleavage factor I; cleavage factor I is a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences; required for genome stability [Source:SGD;Acc:S000005483])

HSP 1 Score: 49.6766 bits (117), Expect = 7.386e-7
Identity = 25/67 (37.31%), Postives = 40/67 (59.70%), Query Frame = 2 
Query:  962 QLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPI 1162
            ++F+G L  + TE+ L+E+F  KYGTV D++I K   +   +    FGFL F     V+E++K + I
Sbjct:  160 KMFIGGLNWDTTEDNLREYFG-KYGTVTDLKIMKDPATGRSR---GFGFLSFEKPSSVDEVVKTQHI 222
[Close]
BLAST of GTPase activating protein vs. Ensembl Yeast
Match: NTF2 (Nuclear envelope protein; interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport [Source:SGD;Acc:S000000811])

HSP 1 Score: 43.5134 bits (101), Expect = 7.242e-6
Identity = 33/115 (28.70%), Postives = 57/115 (49.57%), Query Frame = 2 
Query:  125 TVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDA-VKSHGKSILIQVTGEIA-NNGCDLRRFMQSFLLVEQDLGNFYVLNDIFR 463
            T++Q F   +Y   +     L   Y+ ES L  +    QG  +I +  ++L     +  + +LDA   S    +L+ +TG++  +   + +RF Q F L+  D  ++YV NDIFR
Sbjct:    7 TLAQNFTQFYYNQFDTDRSQLGNLYRNESMLTFETSQLQGAKDIVEKLVSLPFQKVQHRITTLDAQPASPNGDVLVMITGDLLIDEEQNPQRFSQVFHLIP-DGNSYYVFNDIFR 120
[Close]
BLAST of GTPase activating protein vs. Ensembl Nematostella
Match: EDO49764 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFQ7])

HSP 1 Score: 99.7525 bits (247), Expect = 4.913e-25
Identity = 48/127 (37.80%), Postives = 79/127 (62.20%), Query Frame = 2 
Query:  125 TVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI-------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVE-QDLGNFYVLNDIFRYQDQTF 481
             V +EFV Q+YT++N++P  LHRFY + S  +              GQ  I++   +L   +C+  +L +D+  + G  +++QV+GE++NNG  +R+FMQ+F+L   +D+  +YV NDIFRYQD+ F
Sbjct:   10 CVGREFVRQYYTLLNQEPLKLHRFYTKHSWFLHGRAENGPQENPIMGQEAIYEKIKDLNFVDCRTKILQVDSHSTLGSGVVVQVSGELSNNGQPMRKFMQTFVLAPGEDIRKYYVHNDIFRYQDEVF 136
[Close]
BLAST of GTPase activating protein vs. Ensembl Nematostella
Match: EDO44940 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU25])

HSP 1 Score: 50.447 bits (119), Expect = 7.457e-7
Identity = 28/74 (37.84%), Postives = 45/74 (60.81%), Query Frame = 2 
Query:  926 KPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEIL 1147
            +P+  LN P   +LFVG LP++ TE+ L E+F+ ++G V DV I         KP  +FGF+ F + E+ +++L
Sbjct:  190 RPKEELNVP--KKLFVGRLPESTTEKTLMEYFA-QFGEVTDVYIP--------KPFRHFGFVTFASGELAKKVL 252
[Close]
BLAST of GTPase activating protein vs. Ensembl Nematostella
Match: EDO49349 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG33])

HSP 1 Score: 47.3654 bits (111), Expect = 2.607e-6
Identity = 25/65 (38.46%), Postives = 39/65 (60.00%), Query Frame = 2 
Query:  962 QLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHK 1156
            ++F+G L  N TEE LK++FS ++GT+ D  I K    + G     FGF+ + + + V E+LK K
Sbjct:    1 KIFIGGLNWNTTEEGLKDYFS-QWGTIVDCVIMKRDGRSRG-----FGFVTYESSDSVNEVLKKK 59
[Close]
BLAST of GTPase activating protein vs. Ensembl Nematostella
Match: EDO39246 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAM4])

HSP 1 Score: 45.8246 bits (107), Expect = 3.358e-6
Identity = 30/112 (26.79%), Postives = 52/112 (46.43%), Query Frame = 2 
Query:  128 VSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFR 463
            V+++FV  +Y++ +    +L   Y+  S L  +    QG   I    +++       V+ S DA       I++ V G++  N      F Q F L +   G++YV ND+FR
Sbjct:    8 VAKQFVEYYYSVFDSNRNNLAPLYQPGSMLTFEGAQIQGTEAIVAKLVSMPFQQVLHVITSQDAQPLPNGGIIVFVMGQLKVNQDPPLTFSQCFTLFQTTEGSYYVQNDMFR 119
[Close]
BLAST of GTPase activating protein vs. Ensembl Medaka
Match: g3bp1 (G3BP stress granule assembly factor 1 [Source:NCBI gene;Acc:101174841])

HSP 1 Score: 110.538 bits (275), Expect = 1.119e-25
Identity = 58/156 (37.18%), Postives = 88/156 (56.41%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQG--------QHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDL--GNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDI 541
            M++     V +EFV Q+YT++N+ P  LHRFY + S+ V   +   G        Q EIHK  M L   +C   +  +DA  +  + +++QV GE++NN   +R+FMQ+F+L  +      FYV ND+FRYQD+ F   D E    V  ES++ED+
Sbjct:    3 MEKPSAQLVGREFVRQYYTLLNQAPDYLHRFYGKNSSYVHGGVDGNGKPLEPVYGQSEIHKRVMALSFRDCHTKIRHVDAHATLNEGVVVQVMGELSNNLQPMRKFMQTFVLAPEGTVPNKFYVHNDVFRYQDEVFADSDSE----VPEESEDEDL 154

HSP 2 Score: 85.8853 bits (211), Expect = 1.752e-17
Identity = 48/100 (48.00%), Postives = 66/100 (66.00%), Query Frame = 2 
Query:  941 LNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSH-RLNVEQKMGNSRATYKAGRR 1237
            + YPD HQLFVGN+P ++ + ELKEFF  +YG V ++RI      N G  LPNFGF+VF + E V++IL +KPI +    RLNVE+K   +R+  +  RR
Sbjct:  339 VRYPDAHQLFVGNVPHDVDKNELKEFFE-QYGAVLELRI------NSGGKLPNFGFVVFDDSEPVQKILNNKPIKFRGDIRLNVEEK--KTRSAREGDRR 429
[Close]
BLAST of GTPase activating protein vs. Ensembl Medaka
Match: g3bp2 (G3BP stress granule assembly factor 2 [Source:NCBI gene;Acc:101170902])

HSP 1 Score: 108.997 bits (271), Expect = 3.865e-25
Identity = 56/136 (41.18%), Postives = 81/136 (59.56%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI--------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   +           GQ EIHK  M+L+ S C   +  +DA  +    +++QV GE++NNG  +R+FMQ+F+L  E  + N FYV NDIFRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRNSSYVHGGLDPSGKLAEAVYGQAEIHKKVMSLQFSECHTKIRHVDAHATLSDGVVVQVLGELSNNGQPMRKFMQTFVLAPEGSVANKFYVHNDIFRYEDEVF 138

HSP 2 Score: 83.1889 bits (204), Expect = 1.134e-16
Identity = 48/90 (53.33%), Postives = 59/90 (65.56%), Query Frame = 2 
Query:  941 LNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHK---PIYYSSH-RLNVEQK 1198
            + YPD HQLFVGNLP ++ E ELKEFF T YG V ++RI    T   G  LPNFGF+VF + E V++IL  K   PI +    RLNVE+K
Sbjct:  328 VRYPDSHQLFVGNLPHDIDENELKEFFKT-YGNVVELRIN---TKGVGGKLPNFGFVVFDDSEPVQKILGAKVEGPIMFRGEVRLNVEEK 413
[Close]
BLAST of GTPase activating protein vs. Ensembl Medaka
Match: g3bp2 (G3BP stress granule assembly factor 2 [Source:NCBI gene;Acc:101170902])

HSP 1 Score: 108.997 bits (271), Expect = 4.452e-25
Identity = 56/136 (41.18%), Postives = 81/136 (59.56%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDI--------YAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLV-EQDLGN-FYVLNDIFRYQDQTF 481
            M++     V +EFV Q+YT++NK P  LHRFY   S+ V   +           GQ EIHK  M+L+ S C   +  +DA  +    +++QV GE++NNG  +R+FMQ+F+L  E  + N FYV NDIFRY+D+ F
Sbjct:    3 MEKPSPLLVGREFVRQYYTLLNKAPDFLHRFYGRNSSYVHGGLDPSGKLAEAVYGQAEIHKKVMSLQFSECHTKIRHVDAHATLSDGVVVQVLGELSNNGQPMRKFMQTFVLAPEGSVANKFYVHNDIFRYEDEVF 138

HSP 2 Score: 83.5741 bits (205), Expect = 1.048e-16
Identity = 48/90 (53.33%), Postives = 59/90 (65.56%), Query Frame = 2 
Query:  941 LNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHK---PIYYSSH-RLNVEQK 1198
            + YPD HQLFVGNLP ++ E ELKEFF T YG V ++RI    T   G  LPNFGF+VF + E V++IL  K   PI +    RLNVE+K
Sbjct:  347 VRYPDSHQLFVGNLPHDIDENELKEFFKT-YGNVVELRIN---TKGVGGKLPNFGFVVFDDSEPVQKILGAKVEGPIMFRGEVRLNVEEK 432
[Close]
BLAST of GTPase activating protein vs. Ensembl Medaka
Match: g3bp2 (G3BP stress granule assembly factor 2 [Source:NCBI gene;Acc:101170902])

HSP 1 Score: 83.5741 bits (205), Expect = 9.282e-17
Identity = 48/90 (53.33%), Postives = 59/90 (65.56%), Query Frame = 2 
Query:  941 LNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHK---PIYYSSH-RLNVEQK 1198
            + YPD HQLFVGNLP ++ E ELKEFF T YG V ++RI    T   G  LPNFGF+VF + E V++IL  K   PI +    RLNVE+K
Sbjct:  313 VRYPDSHQLFVGNLPHDIDENELKEFFKT-YGNVVELRIN---TKGVGGKLPNFGFVVFDDSEPVQKILGAKVEGPIMFRGEVRLNVEEK 398
[Close]
BLAST of GTPase activating protein vs. Ensembl Medaka
Match: nxt2 (nuclear transport factor 2 like export factor 2 [Source:NCBI gene;Acc:101172743])

HSP 1 Score: 52.7582 bits (125), Expect = 5.839e-8
Identity = 39/123 (31.71%), Postives = 62/123 (50.41%), Query Frame = 2 
Query:  131 SQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAV---KSHGKSILIQVTGEIAN-NGCDLRRFMQSFLLVEQDLGN-----FYVLNDIFRYQD 472
            S+EFV  +Y  M+K+  +L R Y +++TLV +     GQ  +  ++ +L  S  +   L    V    + G++ L+ VTG I    G   R F Q+FLL  Q   N     + + +D FR+QD
Sbjct:   18 SEEFVNIYYDCMDKKRRNLIRLYLDKATLVWNGNAVSGQEALSAFFESLPSSEFQVQTLDCQPVHEQATQGQTTLLVVTGGIVKFEGNKQRFFNQNFLLTAQATPNNDQPVWKIASDCFRFQD 140
[Close]
BLAST of GTPase activating protein vs. Planmine SMEST
Match: SMESG000037949.1 (SMESG000037949.1)

HSP 1 Score: 771.155 bits (1990), Expect = 0.000e+0
Identity = 389/390 (99.74%), Postives = 390/390 (100.00%), Query Frame = 2 
Query:   68 MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIHGEINSWNEIKNCEINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKDISIEIPVEIDTTQDIGQKMEELTIKEKSWAAIINPMSNRPSXXXXXXXXXXXXXXXIQQKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKMGNSRATYKAGRR 1237
            MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIHGEINSWNEIKNCEINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKDI+IEIPVEIDTTQDIGQKMEELTIKEKSWAAIINPMSNRPSKPTAPVAPQPQTAKPIQQKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKMGNSRATYKAGRR
Sbjct:    1 MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIHGEINSWNEIKNCEINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKDINIEIPVEIDTTQDIGQKMEELTIKEKSWAAIINPMSNRPSKPTAPVAPQPQTAKPIQQKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKMGNSRATYKAGRR 390
[Close]
BLAST of GTPase activating protein vs. Planmine SMEST
Match: SMESG000037949.1 (SMESG000037949.1)

HSP 1 Score: 745.732 bits (1924), Expect = 0.000e+0
Identity = 377/378 (99.74%), Postives = 378/378 (100.00%), Query Frame = 2 
Query:  104 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIHGEINSWNEIKNCEINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKDISIEIPVEIDTTQDIGQKMEELTIKEKSWAAIINPMSNRPSXXXXXXXXXXXXXXXIQQKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKMGNSRATYKAGRR 1237
            MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIHGEINSWNEIKNCEINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKDI+IEIPVEIDTTQDIGQKMEELTIKEKSWAAIINPMSNRPSKPTAPVAPQPQTAKPIQQKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKMGNSRATYKAGRR
Sbjct:    1 MDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTLVRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEIANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVEHESKNEDIHGEINSWNEIKNCEINNEPVSQSPQLIEHEEGSEEFINYNIMNEEKDINIEIPVEIDTTQDIGQKMEELTIKEKSWAAIINPMSNRPSKPTAPVAPQPQTAKPIQQKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKMGNSRATYKAGRR 378
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BLAST of GTPase activating protein vs. Planmine SMEST
Match: SMESG000061507.1 (SMESG000061507.1)

HSP 1 Score: 60.8474 bits (146), Expect = 2.261e-11
Identity = 30/69 (43.48%), Postives = 44/69 (63.77%), Query Frame = 2 
Query:  959 HQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIY 1165
            +++FVG  PQN TEEELK FF  KYG +KDV+I   +    G+   ++GF+ F + EV E I+  + I+
Sbjct:   31 NRIFVGGFPQNTTEEELKSFFC-KYGEIKDVKIIPDKA---GQAKGSYGFVTFASQEVAERIITEQKIF 95
[Close]
BLAST of GTPase activating protein vs. Planmine SMEST
Match: SMESG000061507.1 (SMESG000061507.1)

HSP 1 Score: 59.3066 bits (142), Expect = 2.230e-9
Identity = 31/79 (39.24%), Postives = 48/79 (60.76%), Query Frame = 2 
Query:  959 HQLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKP--IYYSSHRLNV 1189
            +++FVG  PQN TEEELK FF  KYG +KDV+I   +    G+   ++GF+ F + EV E I+  +   + +   +LN+
Sbjct:   31 NRIFVGGFPQNTTEEELKSFF-CKYGEIKDVKIIPDKA---GQAKGSYGFVTFASQEVAERIITEQAETLVFRDRKLNI 105
[Close]
BLAST of GTPase activating protein vs. Planmine SMEST
Match: SMESG000025890.1 (SMESG000025890.1)

HSP 1 Score: 57.7658 bits (138), Expect = 6.372e-9
Identity = 31/95 (32.63%), Postives = 55/95 (57.89%), Query Frame = 2 
Query:  929 PQSTLNYPDEH----QLFVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVFHNHEVVEEILKHKPIYYSSHRLNVEQKM 1201
            P+   N P+ H    +LFVG L +++T E L+ +F T YGT+ D  I   + S E +    FGF+ F +++ V++ + +KP    S R++V++ +
Sbjct:   94 PREDSNTPESHMTVNKLFVGGLKKDVTTEHLRHYF-TSYGTITDCEIVTWKDSGESR---GFGFVTFDDYDPVDKAILYKPHQIGSSRVDVKKAL 184
The following BLAST results are available for this feature:
BLAST of GTPase activating protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
G3BP14.276e-2340.58G3BP stress granule assembly factor 1 [Source:HGNC... [more]
G3BP14.276e-2340.58G3BP stress granule assembly factor 1 [Source:HGNC... [more]
G3BP22.888e-2237.50G3BP stress granule assembly factor 2 [Source:HGNC... [more]
G3BP26.714e-2237.50G3BP stress granule assembly factor 2 [Source:HGNC... [more]
G3BP13.521e-2139.29G3BP stress granule assembly factor 1 [Source:HGNC... [more]
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BLAST of GTPase activating protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
gtbp-11.859e-930.71Ras-Gtpase-activating protein SH3 (Three) domain-B... [more]
rbm-344.711e-629.57RNA Binding Motif protein homolog [Source:UniProt... [more]
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BLAST of GTPase activating protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
rin5.164e-2640.43gene:FBgn0015778 transcript:FBtr0082799[more]
rin5.164e-2640.43gene:FBgn0015778 transcript:FBtr0346347[more]
rin5.164e-2640.43gene:FBgn0015778 transcript:FBtr0346346[more]
rin5.164e-2640.43gene:FBgn0015778 transcript:FBtr0082797[more]
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BLAST of GTPase activating protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zgc:563043.407e-2738.73zgc:56304 [Source:ZFIN;Acc:ZDB-GENE-040426-2698][more]
zgc:563042.393e-2539.71zgc:56304 [Source:ZFIN;Acc:ZDB-GENE-040426-2698][more]
zgc:563042.393e-2539.71zgc:56304 [Source:ZFIN;Acc:ZDB-GENE-040426-2698][more]
g3bp29.448e-2540.44GTPase activating protein (SH3 domain) binding pro... [more]
g3bp29.448e-2540.44GTPase activating protein (SH3 domain) binding pro... [more]
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BLAST of GTPase activating protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
g3bp25.162e-2640.43G3BP stress granule assembly factor 2 [Source:NCBI... [more]
g3bp25.491e-2641.91G3BP stress granule assembly factor 2 [Source:NCBI... [more]
g3bp27.041e-2639.46G3BP stress granule assembly factor 2 [Source:NCBI... [more]
fhod11.658e-2539.58formin homology 2 domain containing 1 [Source:Xenb... [more]
fhod13.808e-2539.58formin homology 2 domain containing 1 [Source:Xenb... [more]
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BLAST of GTPase activating protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
G3bp19.583e-2339.86GTPase activating protein (SH3 domain) binding pro... [more]
G3bp25.801e-2137.50GTPase activating protein (SH3 domain) binding pro... [more]
G3bp25.801e-2137.50GTPase activating protein (SH3 domain) binding pro... [more]
G3bp25.801e-2137.50GTPase activating protein (SH3 domain) binding pro... [more]
G3bp27.428e-2137.50GTPase activating protein (SH3 domain) binding pro... [more]
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BLAST of GTPase activating protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O94260|G3BP_SCHPO2.148e-2527.55Putative G3BP-like protein OS=Schizosaccharomyces ... [more]
sp|Q5RB87|G3BP1_PONAB2.034e-2240.58Ras GTPase-activating protein-binding protein 1 OS... [more]
sp|Q13283|G3BP1_HUMAN2.053e-2240.58Ras GTPase-activating protein-binding protein 1 OS... [more]
sp|Q32LC7|G3BP1_BOVIN2.174e-2240.58Ras GTPase-activating protein-binding protein 1 OS... [more]
sp|P97855|G3BP1_MOUSE6.704e-2239.86Ras GTPase-activating protein-binding protein 1 OS... [more]
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BLAST of GTPase activating protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A4V6M60.000e+089.51GTPase activating protein OS=Dugesia japonica OX=6... [more]
D5JG820.000e+086.19GTPase activating protein OS=Dugesia japonica OX=6... [more]
K1QEJ04.657e-4533.01Ras GTPase-activating protein-binding protein 2 OS... [more]
A0A4W3J7663.553e-4232.84Uncharacterized protein OS=Callorhinchus milii OX=... [more]
G3PXB86.937e-4230.52GTPase activating protein (SH3 domain) binding pro... [more]
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BLAST of GTPase activating protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zgc:563041.213e-2538.73G3BP stress granule assembly factor 2 [Source:NCBI... [more]
zgc:563041.291e-2539.71G3BP stress granule assembly factor 2 [Source:NCBI... [more]
g3bp17.929e-2539.58G3BP stress granule assembly factor 1 [Source:NCBI... [more]
g3bp11.558e-2339.71G3BP stress granule assembly factor 1 [Source:NCBI... [more]
nxt24.381e-729.86nuclear transport factor 2 like export factor 2 [S... [more]
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BLAST of GTPase activating protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
g3bp26.437e-2943.38GTPase activating protein (SH3 domain) binding pro... [more]
ENSPMAT00000005655.15.030e-2135.82pep scaffold:Pmarinus_7.0:GL487992:4034:7677:-1 ge... [more]
ENSPMAT00000009806.14.619e-736.00pep scaffold:Pmarinus_7.0:GL479354:9188:12030:-1 g... [more]
HNRNPA03.084e-628.72heterogeneous nuclear ribonucleoprotein A0 [Source... [more]
HNRNPA09.509e-625.53heterogeneous nuclear ribonucleoprotein A0 [Source... [more]
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BLAST of GTPase activating protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
BRE51.295e-727.94Ubiquitin protease cofactor; forms deubiquitinatio... [more]
HRP17.386e-737.31Subunit of cleavage factor I; cleavage factor I is... [more]
NTF27.242e-628.70Nuclear envelope protein; interacts with GDP-bound... [more]
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BLAST of GTPase activating protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO497644.913e-2537.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449407.457e-737.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO493492.607e-638.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO392463.358e-626.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of GTPase activating protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
g3bp11.119e-2537.18G3BP stress granule assembly factor 1 [Source:NCBI... [more]
g3bp23.865e-2541.18G3BP stress granule assembly factor 2 [Source:NCBI... [more]
g3bp24.452e-2541.18G3BP stress granule assembly factor 2 [Source:NCBI... [more]
g3bp29.282e-1753.33G3BP stress granule assembly factor 2 [Source:NCBI... [more]
nxt25.839e-831.71nuclear transport factor 2 like export factor 2 [S... [more]
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BLAST of GTPase activating protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000037949.10.000e+099.74SMESG000037949.1[more]
SMESG000037949.10.000e+099.74SMESG000037949.1[more]
SMESG000061507.12.261e-1143.48SMESG000061507.1[more]
SMESG000061507.12.230e-939.24SMESG000061507.1[more]
SMESG000025890.16.372e-932.63SMESG000025890.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022535 ID=SMED30022535|Name=GTPase activating protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1541bp
TATAAGTTCACTTTTTAAAGACTACTGATTTTCAGTTTCTGTTTGCATTA
ATATTTAGAAATCAATTATGACGGCTAACGGTGACTATATAACTGTTGTA
AATATGGATCGTGACTTAATTACTACAGTCAGTCAAGAATTCGTTCTCCA
ATTTTATACTATAATGAATAAACAACCAGGATCTTTACATCGTTTCTACA
AAGAAGAAAGCACTCTAGTACGCGATGATATTTATGCACAAGGCCAACAT
GAAATTCATAAGTACTACATGAATTTAGAATTAAGTAACTGCAAAGCTGT
CGTTTTGTCTTTGGATGCTGTTAAATCTCACGGTAAAAGCATTCTTATTC
AAGTAACAGGCGAAATTGCTAACAACGGATGTGATTTGCGTAGATTTATG
CAATCATTTTTATTGGTTGAGCAAGATTTAGGAAATTTCTATGTTCTCAA
TGATATCTTTAGATATCAGGACCAAACATTTAAAGTTGAAGATGTTGAAG
AGCCTCCAATGGTAGAGCATGAAAGTAAAAATGAAGATATTCATGGAGAG
ATTAATTCATGGAATGAGATTAAGAATTGTGAGATAAATAATGAGCCTGT
TTCTCAATCTCCGCAATTAATTGAGCACGAAGAAGGAAGTGAAGAATTTA
TCAATTATAATATTATGAACGAGGAAAAGGATATTAGTATTGAAATACCA
GTAGAAATAGATACAACTCAAGATATAGGTCAAAAAATGGAAGAATTGAC
AATCAAAGAAAAATCATGGGCTGCAATTATAAATCCAATGAGTAATCGTC
CATCAAAACCAACTGCTCCAGTCGCTCCACAGCCTCAAACTGCAAAGCCG
ATACAACAAAAACAGATAAATTCCAACGGCGACAACATTGATAAAAGAAA
ACAACGTTTTAATAATGTCAGCGTAAAACCACAGTCCACTTTAAATTACC
CTGATGAACATCAATTGTTTGTTGGTAATTTACCTCAAAATATGACTGAA
GAAGAGTTGAAAGAATTTTTTTCGACTAAATATGGAACGGTTAAAGATGT
TAGAATTCAAAAATCACGGACATCAAACGAAGGAAAGCCTCTTCCAAATT
TTGGATTTCTGGTATTTCATAATCACGAAGTAGTCGAAGAAATACTTAAA
CACAAACCAATCTACTACAGCTCTCACCGCCTAAATGTTGAACAAAAGAT
GGGTAATTCTCGTGCTACTTACAAAGCCGGCCGTCGTTAGAACCTTTAAA
TCTACTGATTATTGTGTCTACAATTTATTTTGTTCCACTAAATTTTAAAG
ACAATAAAATTTGACCCATTGGATGTTTTGATTTAGTAGTGCTTTGGATT
AATTACGAGCTGGCATTTAGAAGTAAATTTGCTGAGCTTTCAGCATAAAA
TAAATTGTTGCACTTTTTTTATTCTTTATTATTAGTTTGCAATACTTTGA
TTATTATTTTGAAAATAATTTTTATTACTATATTTCAATAATTAACTTGA
TGAGGTCATTTGATGTGTGTTGAATATAAAAATAATCAGCG
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protein sequence of SMED30022535-orf-1

>SMED30022535-orf-1 ID=SMED30022535-orf-1|Name=SMED30022535-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=391bp
MTANGDYITVVNMDRDLITTVSQEFVLQFYTIMNKQPGSLHRFYKEESTL
VRDDIYAQGQHEIHKYYMNLELSNCKAVVLSLDAVKSHGKSILIQVTGEI
ANNGCDLRRFMQSFLLVEQDLGNFYVLNDIFRYQDQTFKVEDVEEPPMVE
HESKNEDIHGEINSWNEIKNCEINNEPVSQSPQLIEHEEGSEEFINYNIM
NEEKDISIEIPVEIDTTQDIGQKMEELTIKEKSWAAIINPMSNRPSKPTA
PVAPQPQTAKPIQQKQINSNGDNIDKRKQRFNNVSVKPQSTLNYPDEHQL
FVGNLPQNMTEEELKEFFSTKYGTVKDVRIQKSRTSNEGKPLPNFGFLVF
HNHEVVEEILKHKPIYYSSHRLNVEQKMGNSRATYKAGRR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0003676nucleic acid binding
GO:0000166nucleotide binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR039539Ras_GTPase_bind_prot
IPR035979RBD_domain_sf
IPR000504RRM_dom
IPR012677Nucleotide-bd_a/b_plait_sf
IPR002075NTF2
IPR032710NTF2-like_dom_sf
IPR018222Nuclear_transport_factor_2_euk
Vocabulary: biological process
TermDefinition
GO:0006810transport
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000504RNA recognition motif domainSMARTSM00360rrm1_1coord: 299..375
e-value: 5.4E-15
score: 65.8
IPR000504RNA recognition motif domainPFAMPF00076RRM_1coord: 300..362
e-value: 1.2E-12
score: 47.5
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 298..390
score: 14.351
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 249..389
e-value: 7.0E-17
score: 63.6
IPR002075Nuclear transport factor 2PFAMPF02136NTF2coord: 21..133
e-value: 2.1E-24
score: 86.4
NoneNo IPR availableGENE3DG3DSA:3.10.450.50coord: 9..139
e-value: 2.5E-34
score: 120.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 242..278
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 256..270
NoneNo IPR availableCDDcd12229RRM_G3BPcoord: 295..378
e-value: 6.00078E-33
score: 116.341
IPR039539Ras GTPase-activating protein-binding proteinPANTHERPTHR10693RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEINcoord: 20..381
IPR018222Nuclear transport factor 2, eukaryotePROSITEPS50177NTF2_DOMAINcoord: 21..133
score: 26.182
IPR018222Nuclear transport factor 2, eukaryoteCDDcd00780NTF2coord: 20..135
e-value: 2.22198E-33
score: 118.924
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 292..382
IPR032710NTF2-like domain superfamilySUPERFAMILYSSF54427NTF2-likecoord: 11..136