RING-type domain-containing protein

Overview


Name	RING-type domain-containing protein
Smed ID	SMED30022428
Length (bp)	1353

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of RING-type domain-containing protein (SMED30022428) t-SNE clustered cells

Violin plots show distribution of expression levels for RING-type domain-containing protein (SMED30022428) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RING-type domain-containing protein (SMED30022428) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RING-type domain-containing protein (SMED30022428) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30022428

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30022428	h1SMcG0020556	SmedASXL_006989	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
protonephridia	SMED30022428	h1SMcG0020556	dd_Smed_v4_10741_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30022428	h1SMcG0020556	dd_Smed_v4_10741_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30022428	h1SMcG0020556	dd_Smed_v4_10741_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30022428	h1SMcG0020556	dd_Smed_v4_10741_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30022428	h1SMcG0020556	dd_Smed_v6_10741_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
photoreceptor neuron	SMED30022428	h1SMcG0020556	SMED30022428	smed_20140614	PMID:22884275 Lapan et al., 2012
head region	SMED30022428	h1SMcG0020556	OX_Smed_1.0.21349	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF167 (ring finger protein 167 [Source:HGNC Symbol;Acc:HGNC:24544])

HSP 1 Score: 77.7962 bits (190), Expect = 2.823e-15
Identity = 57/204 (27.94%), Postives = 94/204 (46.08%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTN----LSL---SQEITE--------FAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++ + R   C    ++ NA+   +G  +    N    L++   S+EI +          ER  SS     +   + G ++L V  + F       Y L P T I+ + VL +   +   I R ++       R++ +   K  + ++    YQ G++ D CAICL E+    KLR LPC H +HS+C+D W+   R TCP+C Q
Sbjct:   48 FIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGER--SSEYLRALFVYEKGARVLLVPDNTFP----LGYYLIPFTGIVGLLVLAMGAVM---IARCIQHRK----RLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQ 238

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF167 (ring finger protein 167 [Source:HGNC Symbol;Acc:HGNC:24544])

HSP 1 Score: 77.7962 bits (190), Expect = 4.781e-15
Identity = 57/204 (27.94%), Postives = 94/204 (46.08%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTN----LSL---SQEITE--------FAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++ + R   C    ++ NA+   +G  +    N    L++   S+EI +          ER  SS     +   + G ++L V  + F       Y L P T I+ + VL +   +   I R ++       R++ +   K  + ++    YQ G++ D CAICL E+    KLR LPC H +HS+C+D W+   R TCP+C Q
Sbjct:   83 FIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGER--SSEYLRALFVYEKGARVLLVPDNTFP----LGYYLIPFTGIVGLLVLAMGAVM---IARCIQHRK----RLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQ 273

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF167 (ring finger protein 167 [Source:HGNC Symbol;Acc:HGNC:24544])

HSP 1 Score: 77.7962 bits (190), Expect = 4.781e-15
Identity = 57/204 (27.94%), Postives = 94/204 (46.08%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTN----LSL---SQEITE--------FAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++ + R   C    ++ NA+   +G  +    N    L++   S+EI +          ER  SS     +   + G ++L V  + F       Y L P T I+ + VL +   +   I R ++       R++ +   K  + ++    YQ G++ D CAICL E+    KLR LPC H +HS+C+D W+   R TCP+C Q
Sbjct:   83 FIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGER--SSEYLRALFVYEKGARVLLVPDNTFP----LGYYLIPFTGIVGLLVLAMGAVM---IARCIQHRK----RLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQ 273

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF167 (ring finger protein 167 [Source:HGNC Symbol;Acc:HGNC:24544])

HSP 1 Score: 77.7962 bits (190), Expect = 4.781e-15
Identity = 57/204 (27.94%), Postives = 94/204 (46.08%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTN----LSL---SQEITE--------FAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++ + R   C    ++ NA+   +G  +    N    L++   S+EI +          ER  SS     +   + G ++L V  + F       Y L P T I+ + VL +   +   I R ++       R++ +   K  + ++    YQ G++ D CAICL E+    KLR LPC H +HS+C+D W+   R TCP+C Q
Sbjct:   83 FIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGER--SSEYLRALFVYEKGARVLLVPDNTFP----LGYYLIPFTGIVGLLVLAMGAVM---IARCIQHRK----RLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQ 273

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF167 (ring finger protein 167 [Source:HGNC Symbol;Acc:HGNC:24544])

HSP 1 Score: 77.7962 bits (190), Expect = 4.781e-15
Identity = 57/204 (27.94%), Postives = 94/204 (46.08%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTN----LSL---SQEITE--------FAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++ + R   C    ++ NA+   +G  +    N    L++   S+EI +          ER  SS     +   + G ++L V  + F       Y L P T I+ + VL +   +   I R ++       R++ +   K  + ++    YQ G++ D CAICL E+    KLR LPC H +HS+C+D W+   R TCP+C Q
Sbjct:   83 FIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGER--SSEYLRALFVYEKGARVLLVPDNTFP----LGYYLIPFTGIVGLLVLAMGAVM---IARCIQHRK----RLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQ 273

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C18B12.4 (pep chromosome:WBcel235:X:15036662:15040602:-1 gene:WBGene00007666.1 transcript:C18B12.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C18B12.4)

HSP 1 Score: 75.0998 bits (183), Expect = 2.216e-14
Identity = 39/115 (33.91%), Postives = 62/115 (53.91%), Query Frame = 2

Query:  524 YAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            Y +LF Y +P + +I++ F L     +T  +   +    +   R+      K  + K+ +++Y+ G++ D+CAICL  F+   KLR LPC H FH  CID W+   R  CPLC +
Sbjct:  184 YYELFRYLIPFLVVIVFCFAL---FLITLCVRGCVERRKLNKRRLS-----KRNLKKIPVKKYRLGDDPDTCAICLESFASGEKLRHLPCRHVFHCNCIDVWLTQTRKICPLCKR 290

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: plr-1 (Probable E3 ubiquitin-protein ligase plr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9U2B7])

HSP 1 Score: 58.151 bits (139), Expect = 6.040e-9
Identity = 23/46 (50.00%), Postives = 31/46 (67.39%), Query Frame = 2

Query:  725 EDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCN 862
            ++ C ICL E+ + ++LR L CGH FH KC+D W+ S R  CPLC 
Sbjct:  314 QERCVICLEEYEEGTELRVLFCGHEFHPKCVDPWLLSKR-RCPLCQ 358

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: apc-11 (Anaphase-promoting complex subunit 11 [Source:UniProtKB/Swiss-Prot;Acc:Q20052])

HSP 1 Score: 51.6026 bits (122), Expect = 6.466e-8
Identity = 30/91 (32.97%), Postives = 41/91 (45.05%), Query Frame = 2

Query:  656 IKHSVNMKLFMSKMKI---QRYQDGNEDSCAICLMEFSQNSKLRKLP----------CGHGFHSKCIDHWIQS----HRPTCPLCNQILPI 877
            +K +  M + + K+ +    ++  G ED+C IC MEF     + K P          C H FH  CID WI +     R  CPLC Q   I
Sbjct:   43 LKTNTRMSITVKKLHVCGEWKWLQGGEDTCGICRMEFESACNMCKFPGDDCPLVLGICRHAFHRHCIDKWIAAPTNQPRAQCPLCRQDWTI 133

[Close]

Query:  656 IKHSVNMKLFMSKMKI---QRYQDGNEDSCAICLMEFSQNSKLRKLP----------CGHGFHSKCIDHWIQS----HRPTCPLCNQILPI 877
            +K +  M + + K+ +    ++  G ED+C IC MEF     + K P          C H FH  CID WI +     R  CPLC Q   I
Sbjct:   43 LKTNTRMSITVKKLHVCGEWKWLQGGEDTCGICRMEFESACNMCKFPGDDCPLVLGICRHAFHRHCIDKWIAAPTNQPRAQCPLCRQDWTI 133

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C01G6.4 (pep chromosome:WBcel235:II:9271265:9273042:-1 gene:WBGene00007226.1 transcript:C01G6.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C01G6.4)

HSP 1 Score: 51.6026 bits (122), Expect = 1.176e-7
Identity = 20/48 (41.67%), Postives = 29/48 (60.42%), Query Frame = 2

Query:  716 DGNEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLC 859
            D   + CAIC+++F    ++R LPC H FH +C+D W+     TCP C
Sbjct:   89 DMTSNECAICMIDFEPGERIRFLPCMHSFHQECVDEWLMKSF-TCPSC 135

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: gzl (gene:FBgn0037442 transcript:FBtr0081721)

HSP 1 Score: 67.0106 bits (162), Expect = 1.525e-11
Identity = 27/67 (40.30%), Postives = 40/67 (59.70%), Query Frame = 2

Query:  677 KLFMSKMKIQRYQDGNE----DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            K  + K+ + RY   N     D+C ICL +F ++ KLR LPC H +H+ CID W+  +R  CP+C +
Sbjct:  212 KSMLKKLPVLRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKR 278

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: gzl (gene:FBgn0037442 transcript:FBtr0081722)

HSP 1 Score: 67.0106 bits (162), Expect = 1.525e-11
Identity = 27/67 (40.30%), Postives = 40/67 (59.70%), Query Frame = 2

Query:  677 KLFMSKMKIQRYQDGNE----DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            K  + K+ + RY   N     D+C ICL +F ++ KLR LPC H +H+ CID W+  +R  CP+C +
Sbjct:  212 KSMLKKLPVLRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKR 278

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: gzl (gene:FBgn0037442 transcript:FBtr0081720)

HSP 1 Score: 67.0106 bits (162), Expect = 1.525e-11
Identity = 27/67 (40.30%), Postives = 40/67 (59.70%), Query Frame = 2

Query:  677 KLFMSKMKIQRYQDGNE----DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            K  + K+ + RY   N     D+C ICL +F ++ KLR LPC H +H+ CID W+  +R  CP+C +
Sbjct:  212 KSMLKKLPVLRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKR 278

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: gzl (gene:FBgn0037442 transcript:FBtr0113198)

HSP 1 Score: 67.0106 bits (162), Expect = 1.525e-11
Identity = 27/67 (40.30%), Postives = 40/67 (59.70%), Query Frame = 2

Query:  677 KLFMSKMKIQRYQDGNE----DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            K  + K+ + RY   N     D+C ICL +F ++ KLR LPC H +H+ CID W+  +R  CP+C +
Sbjct:  212 KSMLKKLPVLRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKR 278

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: gol (gene:FBgn0004919 transcript:FBtr0300178)

HSP 1 Score: 59.6918 bits (143), Expect = 2.288e-9
Identity = 26/62 (41.94%), Postives = 34/62 (54.84%), Query Frame = 2

Query:  674 MKLFMSKMKIQRYQDGNEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLC 859
            MK+     K    +D + D CAIC+  +     +R LPC H FH  CID W+  HR TCP+C
Sbjct:  283 MKIPTKTGKFSDEKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHR-TCPMC 343

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: rnf24 (ring finger protein 24 [Source:ZFIN;Acc:ZDB-GENE-041114-40])

HSP 1 Score: 69.3218 bits (168), Expect = 1.105e-13
Identity = 43/119 (36.13%), Postives = 63/119 (52.94%), Query Frame = 2

Query:  530 QLFSYDLPPV-----TLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGN---EDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCN 862
            Q +S+ +P +      L IY+ V G A+FV   I  LL    +I  R++H  + +L+  K  IQ+ +       + CA+CL EF Q  +L   PC H FH KC+  W++  R  CPLCN
Sbjct:    6 QHYSFRMPNIGFQNLPLNIYIVVFGTAIFVF--ILSLLFCCYLI--RLRHQAHKELYAYKQVIQKEKVKELNLHEICAVCLEEFKQKDELGICPCKHAFHRKCLIKWLEV-RKVCPLCN 119

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: rnf167 (ring finger protein 167 [Source:ZFIN;Acc:ZDB-GENE-110126-2])

HSP 1 Score: 72.0182 bits (175), Expect = 3.558e-13
Identity = 29/72 (40.28%), Postives = 45/72 (62.50%), Query Frame = 2

Query:  653 RIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            R++ +   K  + K+ I ++  G+  D CAICL E+ +  KLR LPC H +HS+C+D W+   + TCP+C Q
Sbjct:  209 RLRKNRLSKEQLKKIPIHKFNKGDSYDVCAICLDEYEEGDKLRVLPCSHAYHSRCVDPWLTQTKKTCPVCKQ 280

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: rnf13 (ring finger protein 13 [Source:ZFIN;Acc:ZDB-GENE-040426-772])

HSP 1 Score: 70.8626 bits (172), Expect = 7.044e-13
Identity = 26/61 (42.62%), Postives = 40/61 (65.57%), Query Frame = 2

Query:  686 MSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            + K+ I +++ G+  D CAICL E+ +  +LR LPC H +H KC+D W+   + TCP+C Q
Sbjct:  223 LKKLPIHKFKKGDSYDVCAICLDEYEEGERLRVLPCSHAYHCKCVDPWLTKTKKTCPVCKQ 283

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: rnf150a (ring finger protein 150a [Source:ZFIN;Acc:ZDB-GENE-060213-1])

HSP 1 Score: 70.8626 bits (172), Expect = 7.108e-13
Identity = 50/218 (22.94%), Postives = 98/218 (44.95%), Query Frame = 2

Query:  296 PCYMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPV------TLIIYV-------FVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE------DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMP 892
            P   +IA+  +C  + ++R+A  +N   ++      S S +            V++ MI    G +++ + +     A   S     +      T +++V        ++ +A  V Y I R   + +    + +     K  +SK++++  + G++      D+CA+C+ ++  N  +R LPC H FH  C+D W+Q HR TCP+C   +    G+P
Sbjct:  102 PWIALIAK-GNCTFREKIRHAAALNASAVVIFNVGSSNSNDTITMPHHGTGDVVAI-MIPEPKGREIMALLEKNITVAMHISIGTRNLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRSQRRLGDAAKKAISKLQVRTIRKGDKETDSDFDNCAVCIEDYKPNDVVRILPCRHVFHRNCVDPWLQDHR-TCPMCKMNILKALGIP 316

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-51a16.9 (si:dkey-51a16.9 [Source:ZFIN;Acc:ZDB-GENE-030616-560])

HSP 1 Score: 56.9954 bits (136), Expect = 4.256e-10
Identity = 22/48 (45.83%), Postives = 30/48 (62.50%), Query Frame = 2

Query:  722 NEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            NE +CA+CL EF    +L   PC H FH KC+  W++  R  CP+CN+
Sbjct:   14 NEQTCAVCLEEFRSRDELGVCPCSHAFHKKCLVKWLEI-RSVCPMCNK 60

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf13 (ring finger protein 13 [Source:NCBI gene;Acc:493377])

HSP 1 Score: 73.559 bits (179), Expect = 1.229e-13
Identity = 27/61 (44.26%), Postives = 41/61 (67.21%), Query Frame = 2

Query:  686 MSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            + K+ I +++ G+E D CA+CL E+ +  KLR LPC H +H KC+D W+   + TCP+C Q
Sbjct:  197 LKKLPIHKFKKGDEYDVCAVCLDEYEEGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQ 257

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf13 (ring finger protein 13 [Source:NCBI gene;Acc:493377])

HSP 1 Score: 73.559 bits (179), Expect = 1.322e-13
Identity = 27/61 (44.26%), Postives = 41/61 (67.21%), Query Frame = 2

Query:  686 MSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            + K+ I +++ G+E D CA+CL E+ +  KLR LPC H +H KC+D W+   + TCP+C Q
Sbjct:  240 LKKLPIHKFKKGDEYDVCAVCLDEYEEGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQ 300

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf13 (ring finger protein 13 [Source:NCBI gene;Acc:493377])

HSP 1 Score: 73.559 bits (179), Expect = 1.404e-13
Identity = 27/61 (44.26%), Postives = 41/61 (67.21%), Query Frame = 2

Query:  686 MSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            + K+ I +++ G+E D CA+CL E+ +  KLR LPC H +H KC+D W+   + TCP+C Q
Sbjct:  224 LKKLPIHKFKKGDEYDVCAVCLDEYEEGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQ 284

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: RNF167 (ring finger protein 167 [Source:NCBI gene;Acc:100379947])

HSP 1 Score: 66.2402 bits (160), Expect = 1.371e-11
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 2

Query:  653 RIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLC 859
            R++ +   K  + K+ I +++ G++ D CAICL E+ +  KLR LPC H +H  C+D W+   + +CP+C
Sbjct:  128 RMRRNRLSKEQLKKIPIHKFKKGDDYDVCAICLEEYEEGDKLRVLPCSHAYHCSCVDPWLTKTKKSCPVC 197

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000043564.1 (ring finger protein 128 [Source:NCBI gene;Acc:100145171])

HSP 1 Score: 64.6994 bits (156), Expect = 9.771e-11
Identity = 47/207 (22.71%), Postives = 91/207 (43.96%), Query Frame = 2

Query:  296 PCYMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSV---------VMITLKDGLKLL---NVTKSKFCYAQLFSYDLPPVTL-IIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE------DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLC 859
            P   +I R   C    ++   R    G    +  N  +  E+ E +      TV++         ++  +K G++++    V +    +   +S     V+  I+    +G  +F +   +RL R+ +    ++K     K  + K++++  + G++      DSCA+C+  +  +  +R L C H FH  CID W+  HR TCP+C
Sbjct:   97 PWIALILRGGGCTFTEKIN--RAAERGARAVVVYNNGMDNEVFEMSHPGTKDTVAIMIGNIKGNEIVELIKGGMQVMMVIEVGRKHGSWINHYSIFFVSVSFFIVTAATVGYFIFYSARRWRLTRAQNKKMKQLK--AEAKKAIGKLQLRTIKQGDKVLGPDGDSCAVCIEPYKPSDVVRILTCNHFFHKNCIDPWLLEHR-TCPMC 298

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf167 (ring finger protein 167 [Source:MGI Symbol;Acc:MGI:1917760])

HSP 1 Score: 78.1814 bits (191), Expect = 2.383e-15
Identity = 58/204 (28.43%), Postives = 94/204 (46.08%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIF--ITTNLSL-----SQEITE--------FAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++ + R   C    ++ NA+   +G  +   + +N  L     S+EI +          ER  S+     +   + G ++L V  + F       Y L P T I+ + VL +    T  I R ++       R++ +   K  + ++    YQ G+E D CAICL E+    KLR LPC H +HS+C+D W+   R TCP+C Q
Sbjct:   83 FIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGER--SAEYLRALFVYEKGARVLLVPDNSFP----LGYYLIPFTGIVGLLVLAMG---TVLIVRCIQHRK----RLQRNRLTKEQLKQIPTHDYQKGDEYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQ 273

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf13 (ring finger protein 13 [Source:MGI Symbol;Acc:MGI:1346341])

HSP 1 Score: 73.1738 bits (178), Expect = 1.343e-13
Identity = 47/198 (23.74%), Postives = 88/198 (44.44%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPP-------VTLIIYVFVLGVAVF--VTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++V+ R   C    ++ NA+   +   I    +   S ++      +  +   + + ++  G    N  K +F Y +     L P         LI ++ ++G+ +   V + I + ++              +K    K+ + +++ G+E D CAICL E+    KLR LPC H +H KC+D W+   + TCP+C Q
Sbjct:   93 FIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVD---SDDLISMGSNDIDTLKKIDIPSVFIGESSANSLKDEFTYEKGGHIILVPELSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRNRRNRLRKDQLK----KLPVHKFKKGDEYDVCAICLEEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQ 283

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf43 (ring finger protein 43 [Source:MGI Symbol;Acc:MGI:2442609])

HSP 1 Score: 71.633 bits (174), Expect = 8.703e-13
Identity = 68/247 (27.53%), Postives = 106/247 (42.91%), Query Frame = 2

Query:  215 ELTEISAKHKQIYEFLSVNQTKSEQLKPCYMVIARFTS---CP-----IKRQMRNARTMNFGTIIF-ITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLN-VTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKL------FMSKMKIQRYQDG----------------NEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLC 859
            E+T    K  Q +     N +  + L+P ++ I +  S    P     +  + R A       ++F IT + S ++++ +        T  VV+I   D  KL+  V K++  Y  +     PP      V++L   V   + I  +L S+  I  R  HS    L       +S++  +RYQ G                +   CAICL EFS+  +LR + C H FH  C+D W+  HR TCPLC
Sbjct:   74 EVTPAEGKLMQSHPLYLCNASDDDNLEPGFISIVKLESPRRAPRPCLSLASKARMAGERGANAVLFDITEDRSAAEQLQQPL----GLTKPVVLIWGSDAAKLMEFVYKNRKAYVWI-ELKEPPAGANYDVWILLTVVGTVFVI--ILASVLRIRCRPHHSRPDPLQQRTARAISQLATRRYQAGCRRARAEWPDSGSSCSSTPVCAICLEEFSEGQELRVISCLHEFHRTCVDPWLYQHR-TCPLC 312

[Close]

Query:  215 ELTEISAKHKQIYEFLSVNQTKSEQLKPCYMVIARFTS---CP-----IKRQMRNARTMNFGTIIF-ITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLN-VTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKL------FMSKMKIQRYQDG----------------NEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLC 859
            E+T    K  Q +     N +  + L+P ++ I +  S    P     +  + R A       ++F IT + S ++++ +        T  VV+I   D  KL+  V K++  Y  +     PP      V++L   V   + I  +L S+  I  R  HS    L       +S++  +RYQ G                +   CAICL EFS+  +LR + C H FH  C+D W+  HR TCPLC
Sbjct:   74 EVTPAEGKLMQSHPLYLCNASDDDNLEPGFISIVKLESPRRAPRPCLSLASKARMAGERGANAVLFDITEDRSAAEQLQQPL----GLTKPVVLIWGSDAAKLMEFVYKNRKAYVWI-ELKEPPAGANYDVWILLTVVGTVFVI--ILASVLRIRCRPHHSRPDPLQQRTARAISQLATRRYQAGCRRARAEWPDSGSSCSSTPVCAICLEEFSEGQELRVISCLHEFHRTCVDPWLYQHR-TCPLC 312

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Znrf3 (zinc and ring finger 3 [Source:MGI Symbol;Acc:MGI:3039616])

HSP 1 Score: 70.4774 bits (171), Expect = 1.950e-12
Identity = 70/254 (27.56%), Postives = 109/254 (42.91%), Query Frame = 2

Query:  242 KQIYEFLSVNQTKSEQL----KPCYMVIARFTSCPIKRQMRNARTMNFGTIIF-ITTNLSLSQEITEFAE---REPSSTVSVVMITLKDGLKLLN-VTKSKFCYAQLFSYDLPPVTLIIYVFVLGV--AVFVTYSIY-------------RLLRSLSVIWMRIKHSVNMKLFMSKMKIQR---------YQDGNEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMPHVKC 904
            + +YE+  V   K EQ     KPC  V+ +      KR ++   T     +IF ++ N     ++ + +E   + P     VV +   D +KL+N V K K   A++    LPP     Y F +G+  A FV  S+              R   S++ + ++    +  + F SK K +R            G+   CAICL ++    +LR +PC H FH KC+D W+  H  TCP C   +    G P   C
Sbjct:   14 EDLYEYGWVGVVKLEQPELDPKPCLTVLGK-----AKRAVQRGAT----AVIFDVSENPEAIDQLNQGSEDPLKRP-----VVYVKGADAIKLMNIVNKQKVARARI--QHLPPRQPTEY-FDMGIFLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMETRKFNSKSKGRREGSCGALDTLSSGSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHH-TCPHCRHNIIEQKGNPGAVC 249

[Close]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q91XF4|RN167_MOUSE (E3 ubiquitin-protein ligase RNF167 OS=Mus musculus OX=10090 GN=Rnf167 PE=2 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 1.667e-14
Identity = 58/204 (28.43%), Postives = 94/204 (46.08%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIF--ITTNLSL-----SQEITE--------FAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++ + R   C    ++ NA+   +G  +   + +N  L     S+EI +          ER  S+     +   + G ++L V  + F       Y L P T I+ + VL +    T  I R ++       R++ +   K  + ++    YQ G+E D CAICL E+    KLR LPC H +HS+C+D W+   R TCP+C Q
Sbjct:   83 FIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGER--SAEYLRALFVYEKGARVLLVPDNSFP----LGYYLIPFTGIVGLLVLAMG---TVLIVRCIQHRK----RLQRNRLTKEQLKQIPTHDYQKGDEYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQ 273

[Close]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5XIL0|RN167_RAT (E3 ubiquitin-protein ligase RNF167 OS=Rattus norvegicus OX=10116 GN=Rnf167 PE=2 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 1.696e-14
Identity = 58/204 (28.43%), Postives = 94/204 (46.08%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTN----LSL---SQEITE--------FAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++ + R   C    ++ NA+   +G  +    N    L++   S+EI +          ER  S+     +   + G ++L V  + F       Y L P T I+ + VL +    T  I R ++       R++ +   K  + ++    YQ G+E D CAICL E+    KLR LPC H +HS+C+D W+   R TCP+C Q
Sbjct:   83 FIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGER--SAEYLRALFVYEKGARVLLVPDNSFP----LGYYLIPFTGIVGLLVLAMG---TVLIVRCIQHRK----RLQRNRLTKEQLKQIPTHDYQKGDEYDVCAICLDEYEDGDKLRILPCAHAYHSRCVDPWLTQTRKTCPICKQ 273

[Close]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9H6Y7|RN167_HUMAN (E3 ubiquitin-protein ligase RNF167 OS=Homo sapiens OX=9606 GN=RNF167 PE=1 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 2.296e-14
Identity = 57/204 (27.94%), Postives = 94/204 (46.08%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTN----LSL---SQEITE--------FAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++ + R   C    ++ NA+   +G  +    N    L++   S+EI +          ER  SS     +   + G ++L V  + F       Y L P T I+ + VL +   +   I R ++       R++ +   K  + ++    YQ G++ D CAICL E+    KLR LPC H +HS+C+D W+   R TCP+C Q
Sbjct:   83 FIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGER--SSEYLRALFVYEKGARVLLVPDNTFP----LGYYLIPFTGIVGLLVLAMGAVM---IARCIQHRK----RLQRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQ 273

[Close]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q0VD51|RNF13_BOVIN (E3 ubiquitin-protein ligase RNF13 OS=Bos taurus OX=9913 GN=RNF13 PE=2 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 6.500e-13
Identity = 47/198 (23.74%), Postives = 89/198 (44.95%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQ------LFSYDLP-PVTLIIYVFVLGVAVF--VTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++V+ R   C    ++ NA+   +   I    +   S ++      +      + + ++  G    N  K +F Y +      +  + LP    LI ++ ++G+ +   V + I + ++              +K    K+ + +++ G+E D CAICL E+    KLR LPC H +H KC+D W+   + TCP+C Q
Sbjct:   93 FIVLIRRLDCNFDEKVLNAQRAGYKAAIVHNVD---SDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHIILVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLK----KLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQ 283

[Close]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|O54965|RNF13_MOUSE (E3 ubiquitin-protein ligase RNF13 OS=Mus musculus OX=10090 GN=Rnf13 PE=1 SV=2)

HSP 1 Score: 73.1738 bits (178), Expect = 9.394e-13
Identity = 47/198 (23.74%), Postives = 88/198 (44.44%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPP-------VTLIIYVFVLGVAVF--VTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            ++V+ R   C    ++ NA+   +   I    +   S ++      +  +   + + ++  G    N  K +F Y +     L P         LI ++ ++G+ +   V + I + ++              +K    K+ + +++ G+E D CAICL E+    KLR LPC H +H KC+D W+   + TCP+C Q
Sbjct:   93 FIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVD---SDDLISMGSNDIDTLKKIDIPSVFIGESSANSLKDEFTYEKGGHIILVPELSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRNRRNRLRKDQLK----KLPVHKFKKGDEYDVCAICLEEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQ 283

[Close]

BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A2R5LGQ8 (Putative e3 ubiquitin-protein ligase rnf13 OS=Ornithodoros turicata OX=34597 PE=4 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 2.945e-15
Identity = 58/209 (27.75%), Postives = 107/209 (51.20%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIF----ITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVF----VLG---VAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMP 892
            +++IARF  C +  + R A+   +   +     +  N   +Q++ +    +    +  VM++ + G+KL   T       +L+  +   V LI YV     ++G   VA+F  Y + + +R     W + + S   K  + ++   +Y+ G+  ++CAIC+ ++ +  KLR LPC H +H KCID W+  +R TCP+C + + +P GMP
Sbjct:   96 FVLIARF-ECSLGDKARYAQEAGYDVAVIYDRKVHINPREAQQVLKHDSDDVDVNIYAVMVSEESGIKLRRYTYKDDYQVKLYPENF--VNLISYVVPFLAIIGLCTVAIFC-YVVGKYVRD----WCKRRKSRLSKRHLRQIPTTKYKKGDAYETCAICIEDYVEGDKLRVLPCSHAYHCKCIDTWLLENRRTCPICKRKVRLP-GMP 295

[Close]

BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A095BT88 (E3 ubiquitin-protein ligase RNF13 OS=Schistosoma haematobium OX=6185 GN=MS3_00174 PE=4 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 6.928e-15
Identity = 65/230 (28.26%), Postives = 110/230 (47.83%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNF-GTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVT-------KSKFCYAQLFSYDLP-PVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE--DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMPHVKCAVCSTSVIGNHNNSATFF 958
            Y  + +   C    ++ NA+   + G I+F T N  +        ER     +  VM+  + GLKL+N +         +F  + +  Y LP    L+  + V+G+++ +    + +   L   W RI+     +  + ++ ++R++ G +  D C ICL ++    KLR LPC H FH KCID W+  +R  CP+CNQI+ +P G P        T  +G +NN+  F 
Sbjct:   86 YFALIQRGGCDFDLKVLNAQQKGYTGVIVFNTINDKIFP--MNGGERASQILIPSVMVDKRAGLKLMNYSINSSINGSREFMISIVSFYGLPLKYVLLALLIVVGISLLILVIAFTI--HLCRFWRRIRRGRLSRRHLRQLVLKRFKKGLDPYDVCCICLEDYVDRDKLRLLPCQHAFHMKCIDPWLLCNRRRCPICNQIVELP-GAPSTS---DETETVGPNNNNNGFL 307

[Close]

BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A4Z2DPM2 (E3 ubiquitin-protein ligase OS=Schistosoma japonicum OX=6182 GN=EWB00_010752 PE=4 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 7.547e-15
Identity = 67/208 (32.21%), Postives = 105/208 (50.48%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNF-GTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLN---VTKSK-FCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSV----IWMRIKHSVNMKLFMSKMKIQRYQDGNE--DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMP 892
            Y V+ +   C    ++ NA+   + G I+F T N  +     +  ER     +  VM+  + GLKL+N   V  SK F  + +  Y LP    + YV +L + + V  S+  L+ S ++     W RI      +  + ++ ++R+  G +  D C ICL ++    KLR LPC H FH KCID W+  +R  CP+CNQI+ +P G P
Sbjct:   95 YFVLIQRGGCYFDLKVLNAQQEGYTGVIVFNTMNDKIFP--MDGGERASQILIPSVMVDKRAGLKLMNYSIVNGSKEFVISMVSFYSLP----LKYV-LLSLLILVGISLLILVISFTIHLCRFWRRIHRGRLSRRHLRRLVLKRFTKGLDPYDVCCICLEDYVDRDKLRLLPCQHAFHMKCIDPWLLCNRRHCPICNQIVELP-GAP 294

[Close]

BLAST of RING-type domain-containing protein vs. TrEMBL
Match: L7M8H2 (Putative e3 ubiquitin-protein ligase rnf13 OS=Rhipicephalus pulchellus OX=72859 PE=2 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 8.731e-15
Identity = 61/219 (27.85%), Postives = 104/219 (47.49%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSS--------------TVSVVMITLKDGLKLLNVT-KSKF-------CYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGN-EDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGM 889
            +++IARF  C +  + R A+   +   +        S         EP                T+  V+++ + G++L   T K  +        +  +FSY LP   +I+ V VLG+AVFV    +R        W + + S   + F+ ++   +Y+ G+  ++CAICL ++ +  KLR LPC H +H KCI  W+  +R TCP+C + + +P GM
Sbjct:   96 FVLIARF-ECGLSDKTRFAQEAGYDVAVIYDRKAHNSGPFETHITPEPKYYPIRGNGLKDTDDITIYAVIVSEETGIRLKRYTYKDDYEVKLYPESFQSIFSYLLP-FLVIVGVCVLGLAVFVLARCFR-------DWRKKRKSRLSRKFLRQLPTTKYKKGDIYETCAICLEDYVEGDKLRILPCAHAYHCKCIKPWLLHNRRTCPICKRKVVLP-GM 304

[Close]

BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A0V1LSV6 (Stromal cell-derived factor 2 OS=Trichinella nativa OX=6335 GN=RNF13 PE=4 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 1.700e-14
Identity = 60/197 (30.46%), Postives = 97/197 (49.24%), Query Frame = 2

Query:  302 YMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQL----FSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFM----SKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            Y  IAR  +C   ++  NA+   + + +FI  +      +      E   T+  +MI+   GLKL+N   SK  Y  L    +SY+     LI  V V+GV+  +      LL  +S  W R +  +  +        K+  ++Y+ G+E + CAICL +F+   K+R LPCGH +H  C+D W+  +R  CP+C +
Sbjct:  297 YYAIARRGNCSFAKKAFNAQKAGY-SGLFIYNDYDEVFPMAGDGIYEKKVTIPALMISRTCGLKLINDYPSKDGYGVLIRLWWSYNNALKFLIPLVAVIGVSFLI------LLSVVSFRWFRNQQRLQRRRLTRRQLKKIPNRKYKKGDEHEMCAICLEDFADGDKMRLLPCGHVYHCACVDPWLLKNRKVCPVCKR 486

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf167 (ring finger protein 167 [Source:NCBI gene;Acc:103022714])

HSP 1 Score: 76.6406 bits (187), Expect = 9.598e-15
Identity = 47/148 (31.76%), Postives = 77/148 (52.03%), Query Frame = 2

Query:  473 TLKDGLKLLNVTKSKFCYAQLFSYDLP--------------PVT--LIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            T+ D + + +V  S + Y  L S+ +P              P+T  LI +  V+G+ +F+   I   +R +     R++ +   K  + K+ I ++  G+E D CAICL E+ +  KLR LPC H +H KC+D W+   + TCP+C Q
Sbjct:  140 TIADMIDIPSVFTSYYAYQILRSFIIPEKGAYVILKPDFSFPLTYYLIPFTGVVGL-IFIVMVIILAVRCVQY-RKRMRKNRLSKEQLKKIPIHKFNKGDEYDVCAICLDEYEEGDKLRVLPCSHAYHCKCVDPWLTQTKKTCPVCKQ 285

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf13 (ring finger protein 13 [Source:NCBI gene;Acc:103029118])

HSP 1 Score: 74.3294 bits (181), Expect = 3.804e-14
Identity = 50/223 (22.42%), Postives = 98/223 (43.95%), Query Frame = 2

Query:  227 ISAKHKQIYEFLSVNQTKSEQLKPCYMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQ------LFSYDLP-PVTLIIYVFVLGVAVF--VTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGN-EDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            + A+ +   E +    TK  +    ++V+ +   C    ++ NA+   +   I    +   S ++      +      + + ++  G    N  K ++ Y +      +  + LP    LI ++ ++G+ +   V + I + ++              +K    K+ I +Y+ G+  D CAICL E+ +  KLR LPC H +H KC+D W+   + TCP+C Q
Sbjct:   69 VGARPENACEPIEPPPTKGRENSSTFIVLIKRFDCNFDIKVLNAQRAGYKAAIVHNVD---SDDLISMGSNDIDIVKQIDIPSVFIGEDAANALKEEYTYEKGGHVIVMPDFSLPLEYYLIPFLIIVGICLILIVVFMITKFVQDRHRARRSRLRKDQLK----KLPIHKYKKGDVYDVCAICLDEYEEGEKLRVLPCSHAYHCKCVDPWLTKTKKTCPVCKQ 284

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf150a (ring finger protein 150 [Source:NCBI gene;Acc:103037093])

HSP 1 Score: 70.0922 bits (170), Expect = 1.434e-12
Identity = 53/223 (23.77%), Postives = 99/223 (44.39%), Query Frame = 2

Query:  284 EQLKPCYMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNV--------------TKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE------DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMP 892
            E   P   +IAR  +C  + ++R A ++N   ++      S S E      +     V++ MI    G ++  +              T++   Y    S     ++ I+ + ++ +A  V Y I R   + +    + +     K  +SK++++  + G++      D+CA+C+  +  N  +R LPC H FH  C+D W+Q HR TCP+C   +    G+P
Sbjct:  102 EHQGPWIALIAR-GNCTYREKIRLAASLNASAVVIFNVGSSNSNETITMPHQGTGDIVAI-MIPEPKGREIAALLEKNVSVIMHITIGTRNLQKYVSRTSVVFVSISFIV-LMIISLAWLVFYYIQRFRYASARDRNQRRLGDAAKKAISKLQVRTIRKGDKETESEFDNCAVCIETYKPNDVVRILPCRHVFHKNCVDPWLQDHR-TCPMCKMNILKALGIP 320

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf24 (ring finger protein 24 [Source:ZFIN;Acc:ZDB-GENE-041114-40])

HSP 1 Score: 63.5438 bits (153), Expect = 8.120e-12
Identity = 38/100 (38.00%), Postives = 53/100 (53.00%), Query Frame = 2

Query:  563 LIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCN 862
            L IY+ V G A+FV   I  LL    +I  R++H  + +L+  K    +  +     CA+CL EF Q  +L   PC H FH KC+  W++  R  CPLCN
Sbjct:   22 LNIYIVVFGTAIFVF--ILSLLFCCYLI--RLRHQAHKELYAYK----QVSNQQIHICAVCLEEFKQKDELGICPCKHAFHRKCLIKWLEV-RKVCPLCN 112

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf150a (ring finger protein 150 [Source:NCBI gene;Acc:103037093])

HSP 1 Score: 67.3958 bits (163), Expect = 9.638e-12
Identity = 51/212 (24.06%), Postives = 95/212 (44.81%), Query Frame = 2

Query:  284 EQLKPCYMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNV--------------TKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE------DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLC 859
            E   P   +IAR  +C  + ++R A ++N   ++      S S E      +     V++ MI    G ++  +              T++   Y    S     ++ I+ + ++ +A  V Y I R   + +    + +     K  +SK++++  + G++      D+CA+C+  +  N  +R LPC H FH  C+D W+Q HR TCP+C
Sbjct:  102 EHQGPWIALIAR-GNCTYREKIRLAASLNASAVVIFNVGSSNSNETITMPHQGTGDIVAI-MIPEPKGREIAALLEKNVSVIMHITIGTRNLQKYVSRTSVVFVSISFIV-LMIISLAWLVFYYIQRFRYASARDRNQRRLGDAAKKAISKLQVRTIRKGDKETESEFDNCAVCIETYKPNDVVRILPCRHVFHKNCVDPWLQDHR-TCPMC 309

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003771.1 (pep scaffold:Pmarinus_7.0:GL488469:4:5386:-1 gene:ENSPMAG00000003449.1 transcript:ENSPMAT00000003771.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.0846 bits (157), Expect = 1.615e-13
Identity = 23/46 (50.00%), Postives = 30/46 (65.22%), Query Frame = 2

Query:  728 DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            D CAICL E+ +  +LR LPC H FH KC+D W+   R  CP+C +
Sbjct:    5 DVCAICLEEYEEGERLRVLPCAHAFHCKCVDPWLTQQRKNCPVCKR 50

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: rnf150a (ring finger protein 150a [Source:ZFIN;Acc:ZDB-GENE-060213-1])

HSP 1 Score: 63.5438 bits (153), Expect = 2.262e-11
Identity = 35/118 (29.66%), Postives = 60/118 (50.85%), Query Frame = 2

Query:  569 IYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNM----KLFMSKMKIQRYQDGNE------DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMP 892
            I + ++ +A  V Y + RL  + +    R +H   +    K  M+K+ ++  + G++      D+CA+C+  +  N  +R LPC H FH  C+D W+  HR TCP+C   +    G P
Sbjct:  228 IVLMIISLAWLVFYYVQRLRYASA----RDRHQRRLGDAAKKAMTKLPLKTIKKGDQETEPDFDNCAVCIEGYKPNDVVRILPCKHLFHKACVDPWLLDHR-TCPMCKLNILKALGFP 340

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: si:ch1073-392o20.1 (ring finger protein 122 [Source:HGNC Symbol;Acc:HGNC:21147])

HSP 1 Score: 53.1434 bits (126), Expect = 1.100e-9
Identity = 20/47 (42.55%), Postives = 30/47 (63.83%), Query Frame = 2

Query:  725 EDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            E +CA+CL +F +  +L   PC H FH KC+  W++  R  CP+CN+
Sbjct:   14 EQTCAVCLEDFREKDELAVCPCKHAFHRKCLVKWLEI-RNACPMCNK 59

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003380.1 (pep scaffold:Pmarinus_7.0:GL476517:4028:13530:1 gene:ENSPMAG00000003092.1 transcript:ENSPMAT00000003380.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.6026 bits (122), Expect = 1.117e-8
Identity = 22/50 (44.00%), Postives = 32/50 (64.00%), Query Frame = 2

Query:  728 DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPI 877
            ++CA+CL +F+   KL   PC H FH KC+  W++  R +CP+C  I PI
Sbjct:   31 ETCAVCLEDFTLKDKLGICPCRHAFHRKCLVRWLEI-RKSCPMC--ITPI 77

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: rnf103 (ring finger protein 103 [Source:ZFIN;Acc:ZDB-GENE-040912-171])

HSP 1 Score: 52.373 bits (124), Expect = 1.363e-7
Identity = 19/45 (42.22%), Postives = 27/45 (60.00%), Query Frame = 2

Query:  734 CAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQI 868
            C +CL  +S    L  LPCGH FH++CI  W++  R  CP+C  +
Sbjct:  640 CVVCLEAYSLGCLLTCLPCGHAFHARCIAIWLEGGRHCCPVCRWL 684

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Yeast
Match: HRD1 (Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) of misfolded proteins; upon autoubiquitination triggers retrotranslocation of misfolded proteins to cytosol for degradation; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger; likely plays a general role in targeting proteins that persistently associate with and potentially obstruct the ER-localized translocon [Source:SGD;Acc:S000005373])

HSP 1 Score: 49.6766 bits (117), Expect = 6.914e-7
Identity = 28/104 (26.92%), Postives = 56/104 (53.85%), Query Frame = 2

Query:  602 VTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQD-GNEDS-CAICLMEF----------SQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPI 877
            V + I  L +S + +W   +++  +   +  + +++ Q+  N+D+ C IC+ E           ++N K ++LPCGH  H  C+ +W++  + TCP+C   LP+
Sbjct:  303 VVWDILALYQSGTSLWKIWRNNKQLDDTLVTVTVEQLQNSANDDNICIICMDELIHSPNQQTWKNKNKKPKRLPCGHILHLSCLKNWMERSQ-TCPICR--LPV 403

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO36379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIX4])

HSP 1 Score: 65.0846 bits (157), Expect = 1.289e-11
Identity = 27/60 (45.00%), Postives = 38/60 (63.33%), Query Frame = 2

Query:  692 KMKIQRYQDGNE--DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            K++I     G+E  D CAICL E+ +  KLR LPC H +H KC+D W+   + TCP+C +
Sbjct:  250 KLRILPCDHGDEYYDVCAICLDEYKEGDKLRILPCDHAYHCKCVDPWLTEGKRTCPVCKR 309

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO31118 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYV5])

HSP 1 Score: 57.3806 bits (137), Expect = 1.231e-10
Identity = 23/46 (50.00%), Postives = 32/46 (69.57%), Query Frame = 2

Query:  707 RYQDGNED----SCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQ 832
            R+   N+D    SC +C+M+++   KLRKLPC H FHSKCID W++
Sbjct:   49 RFSASNKDMSNGSCVVCMMDYTNREKLRKLPCNHDFHSKCIDRWLK 94

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO41758 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3E3])

HSP 1 Score: 60.4622 bits (145), Expect = 3.131e-10
Identity = 54/208 (25.96%), Postives = 92/208 (44.23%), Query Frame = 2

Query:  287 QLKPCYMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTK--SKFCYAQLF------SYDLPPVTLI------IYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE---DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLC 859
            Q++P ++ + R  SC    ++ NA   N  T I I  +      IT      P+  +  V IT + G  L +  +  S+  YA++        + + P +++      I + V+ +A  V Y + R     +      + S   K  ++K+  +  +   E   DSC +CL  +     +R LPC H +H  CID W+  HR TCP+C
Sbjct:   64 QVRP-WIALVRRGSCRFNTKIANAFKYN-ATAIIIYDSQDSDDVITMLNAGAPN--LVSVSITKRLGEYLADKLRNNSRAIYAEILVGEKHSKWRVNPTSVLFVSVSFIVLMVISLAWLVFYYVQRFRYVHARDKTEKRLSSAAKKAIAKLPTRTVKKDEEEEIDSCPVCLDGYKSGEVIRILPCNHEYHKLCIDPWLVEHR-TCPMC 266

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO49283 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH29])

HSP 1 Score: 50.8322 bits (120), Expect = 2.742e-8
Identity = 18/45 (40.00%), Postives = 31/45 (68.89%), Query Frame = 2

Query:  722 NEDS-CAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCP 853
            N+D+ C +CL++F +   +R LPC H +H++CID W++ H+   P
Sbjct:   45 NDDARCVVCLVDFEEKQLVRTLPCLHEYHTRCIDKWLKVHKTLEP 89

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO36209 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJC0])

HSP 1 Score: 46.595 bits (109), Expect = 6.583e-7
Identity = 27/82 (32.93%), Postives = 36/82 (43.90%), Query Frame = 2

Query:  692 KMKIQRYQDG------------NEDSCAICLMEFSQNSKLRKLP----------CGHGFHSKCIDHWIQS--HRPTCPLCNQ 865
            K+KI+R+  G            N+D+C IC M F       K+P          C H FH  CI  W+ S  H+  CP+C Q
Sbjct:    2 KVKIKRFHSGRWVGVATWKWMANDDNCGICRMPFDGCCPDCKVPGDDCPLVWGRCSHVFHMHCILKWLNSQLHQQLCPMCRQ 83

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: rnf13 (ring finger protein 13 [Source:NCBI gene;Acc:101161477])

HSP 1 Score: 82.8037 bits (203), Expect = 6.085e-17
Identity = 41/111 (36.94%), Postives = 61/111 (54.95%), Query Frame = 2

Query:  536 FSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
              Y L P  LI+ + ++ +AVF+   I + ++     W        +K    K+ I +YQ G+  D CAICL E+ +  KLR LPC H +HSKC+D W+   + TCP+C Q
Sbjct:  179 LEYYLLPFLLIVAICLILIAVFM---ITKAVQDCRKAWKSRLRKDQLK----KLPIHKYQKGDSYDVCAICLDEYEEGDKLRVLPCSHAYHSKCVDPWLTKTKKTCPVCKQ 282

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: rnf24 (ring finger protein 24 [Source:NCBI gene;Acc:101163789])

HSP 1 Score: 68.5514 bits (166), Expect = 1.600e-13
Identity = 42/117 (35.90%), Postives = 62/117 (52.99%), Query Frame = 2

Query:  536 FSYDLPPV-----TLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGN---EDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCN 862
            +S+ +P +      L IY+ V G A+FV   I  LL    +I  R++H  + +L+  K  IQ+ +       + CA+CL EF Q  +L   PC H FH KC+  W++  R  CPLCN
Sbjct:    8 YSFRMPNIGFQNLPLNIYIVVFGTAIFVF--ILSLLFCCYLI--RLRHQAHKELYAYKQVIQKEKVKELNLHEICAVCLEEFKQKDELGICPCKHAFHRKCLIKWLEV-RKVCPLCN 119

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: rnf167 (E3 ubiquitin-protein ligase RNF167 [Source:NCBI gene;Acc:101167225])

HSP 1 Score: 70.8626 bits (172), Expect = 6.794e-13
Identity = 29/72 (40.28%), Postives = 44/72 (61.11%), Query Frame = 2

Query:  653 RIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            RI+ +   K  + ++   R+  G++ D CAICL E+ +  KLR LPC H +H KC+D W+   + TCP+C Q
Sbjct:  213 RIRKNRLTKEQLKRIPTHRFTKGDDYDVCAICLDEYEEGDKLRVLPCSHAYHCKCVDPWLTQTKKTCPVCKQ 284

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: rnf167 (E3 ubiquitin-protein ligase RNF167 [Source:NCBI gene;Acc:101167225])

HSP 1 Score: 70.8626 bits (172), Expect = 7.141e-13
Identity = 29/72 (40.28%), Postives = 44/72 (61.11%), Query Frame = 2

Query:  653 RIKHSVNMKLFMSKMKIQRYQDGNE-DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQ 865
            RI+ +   K  + ++   R+  G++ D CAICL E+ +  KLR LPC H +H KC+D W+   + TCP+C Q
Sbjct:  213 RIRKNRLTKEQLKRIPTHRFTKGDDYDVCAICLDEYEEGDKLRVLPCSHAYHCKCVDPWLTQTKKTCPVCKQ 284

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: rnf24 (ring finger protein 24 [Source:NCBI gene;Acc:101163789])

HSP 1 Score: 64.3142 bits (155), Expect = 3.832e-12
Identity = 40/114 (35.09%), Postives = 58/114 (50.88%), Query Frame = 2

Query:  536 FSYDLPPV-----TLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCN 862
            +S+ +P +      L IY+ V G A+FV   I  LL    +I  R++H  + +L+        Y+      CA+CL EF Q  +L   PC H FH KC+  W++  R  CPLCN
Sbjct:    8 YSFRMPNIGFQNLPLNIYIVVFGTAIFVF--ILSLLFCCYLI--RLRHQAHKELYA-------YKQVRMHICAVCLEEFKQKDELGICPCKHAFHRKCLIKWLEV-RKVCPLCN 109

[Close]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000010565.1 (SMESG000010565.1)

HSP 1 Score: 828.55 bits (2139), Expect = 0.000e+0
Identity = 397/397 (100.00%), Postives = 397/397 (100.00%), Query Frame = 2

Query:   26 MIIWLVAILLQTELAVSNYMIIKDFSDGRRVLYLDIIKISHDHCMGPIFNLKTQSLCYEEHKLELTEISAKHKQIYEFLSVNQTKSEQLKPCYMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMPHVKCAVCSTSVIGNHNNSATFFDDRFSQNTVLTVDLENINQGSNRTRLADDISYEMESSDPRSHNPMEQNEIRIDGFLTCDFNTRSDGIVEYPKSVEVSNVTTNDETV 1216
            MIIWLVAILLQTELAVSNYMIIKDFSDGRRVLYLDIIKISHDHCMGPIFNLKTQSLCYEEHKLELTEISAKHKQIYEFLSVNQTKSEQLKPCYMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMPHVKCAVCSTSVIGNHNNSATFFDDRFSQNTVLTVDLENINQGSNRTRLADDISYEMESSDPRSHNPMEQNEIRIDGFLTCDFNTRSDGIVEYPKSVEVSNVTTNDETV
Sbjct:    1 MIIWLVAILLQTELAVSNYMIIKDFSDGRRVLYLDIIKISHDHCMGPIFNLKTQSLCYEEHKLELTEISAKHKQIYEFLSVNQTKSEQLKPCYMVIARFTSCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMITLKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRLLRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMPHVKCAVCSTSVIGNHNNSATFFDDRFSQNTVLTVDLENINQGSNRTRLADDISYEMESSDPRSHNPMEQNEIRIDGFLTCDFNTRSDGIVEYPKSVEVSNVTTNDETV 397

[Close]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000013169.1 (SMESG000013169.1)

HSP 1 Score: 65.0846 bits (157), Expect = 2.557e-11
Identity = 26/70 (37.14%), Postives = 42/70 (60.00%), Query Frame = 2

Query:  677 KLFMSKMKIQRYQDGNE--DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIP 880
            K  + K+ ++++  G +  ++CAICL +F    KLR LPC H +H+ CID W+   +  CP+C   + IP
Sbjct:  188 KCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIP 257

[Close]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000013169.1 (SMESG000013169.1)

HSP 1 Score: 65.0846 bits (157), Expect = 2.849e-11
Identity = 26/70 (37.14%), Postives = 42/70 (60.00%), Query Frame = 2

Query:  677 KLFMSKMKIQRYQDGNE--DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIP 880
            K  + K+ ++++  G +  ++CAICL +F    KLR LPC H +H+ CID W+   +  CP+C   + IP
Sbjct:  203 KCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIP 272

[Close]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000013169.1 (SMESG000013169.1)

HSP 1 Score: 64.6994 bits (156), Expect = 3.304e-11
Identity = 26/70 (37.14%), Postives = 42/70 (60.00%), Query Frame = 2

Query:  677 KLFMSKMKIQRYQDGNE--DSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIP 880
            K  + K+ ++++  G +  ++CAICL +F    KLR LPC H +H+ CID W+   +  CP+C   + IP
Sbjct:  169 KCHLKKIPLKKFVKGRDPFETCAICLDDFKDGDKLRILPCNHAYHANCIDPWLLKQKRNCPICKYRIKIP 238

[Close]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000016770.1 (SMESG000016770.1)

HSP 1 Score: 55.8398 bits (133), Expect = 4.762e-8
Identity = 30/92 (32.61%), Postives = 43/92 (46.74%), Query Frame = 2

Query:  611 SIYRLLRSLSVIWMRIK---------HSVNMKLFMSKMKIQRYQDGNEDSCAICLMEFSQNSKLRKLPCGHGFHSKCIDHWIQSHRPTCPLC 859
            S+ +L   L   W  I          H     L  S   ++R     +D C +CL EF +N  LR L C H +H  C+D W++ +R TCP+C
Sbjct:  667 SVIQLALHLETSWRGINPSELAQLPCHYYKNDLNASNTDLER-----QDKCMVCLEEFLENDHLRTLSCSHQYHVMCVDKWLRMNR-TCPMC 752

The following BLAST results are available for this feature:

BLAST of RING-type domain-containing protein vs. Ensembl Human
BLAST of RING-type domain-containing protein vs. Ensembl Celegans
BLAST of RING-type domain-containing protein vs. Ensembl Fly
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
BLAST of RING-type domain-containing protein vs. TrEMBL
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
BLAST of RING-type domain-containing protein vs. Ensembl Yeast
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
BLAST of RING-type domain-containing protein vs. Planmine SMEST

BLAST of RING-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RNF167	2.823e-15	27.94	ring finger protein 167 [Source:HGNC Symbol;Acc:HG...	[more]
RNF167	4.781e-15	27.94	ring finger protein 167 [Source:HGNC Symbol;Acc:HG...	[more]
RNF167	4.781e-15	27.94	ring finger protein 167 [Source:HGNC Symbol;Acc:HG...	[more]
RNF167	4.781e-15	27.94	ring finger protein 167 [Source:HGNC Symbol;Acc:HG...	[more]
RNF167	4.781e-15	27.94	ring finger protein 167 [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
C18B12.4	2.216e-14	33.91	pep chromosome:WBcel235:X:15036662:15040602:-1 gen...	[more]
plr-1	6.040e-9	50.00	Probable E3 ubiquitin-protein ligase plr-1 [Sourc...	[more]
apc-11	6.466e-8	32.97	Anaphase-promoting complex subunit 11 [Source:Uni...	[more]
apc-11	6.466e-8	32.97	Anaphase-promoting complex subunit 11 [Source:Uni...	[more]
C01G6.4	1.176e-7	41.67	pep chromosome:WBcel235:II:9271265:9273042:-1 gene...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gzl	1.525e-11	40.30	gene:FBgn0037442 transcript:FBtr0081721	[more]
gzl	1.525e-11	40.30	gene:FBgn0037442 transcript:FBtr0081722	[more]
gzl	1.525e-11	40.30	gene:FBgn0037442 transcript:FBtr0081720	[more]
gzl	1.525e-11	40.30	gene:FBgn0037442 transcript:FBtr0113198	[more]
gol	2.288e-9	41.94	gene:FBgn0004919 transcript:FBtr0300178	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rnf24	1.105e-13	36.13	ring finger protein 24 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
rnf167	3.558e-13	40.28	ring finger protein 167 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
rnf13	7.044e-13	42.62	ring finger protein 13 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
rnf150a	7.108e-13	22.94	ring finger protein 150a [Source:ZFIN;Acc:ZDB-GENE...	[more]
si:dkey-51a16.9	4.256e-10	45.83	si:dkey-51a16.9 [Source:ZFIN;Acc:ZDB-GENE-030616-5...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rnf13	1.229e-13	44.26	ring finger protein 13 [Source:NCBI gene;Acc:49337...	[more]
rnf13	1.322e-13	44.26	ring finger protein 13 [Source:NCBI gene;Acc:49337...	[more]
rnf13	1.404e-13	44.26	ring finger protein 13 [Source:NCBI gene;Acc:49337...	[more]
RNF167	1.371e-11	37.14	ring finger protein 167 [Source:NCBI gene;Acc:1003...	[more]
ENSXETT00000043564.1	9.771e-11	22.71	ring finger protein 128 [Source:NCBI gene;Acc:1001...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rnf167	2.383e-15	28.43	ring finger protein 167 [Source:MGI Symbol;Acc:MGI...	[more]
Rnf13	1.343e-13	23.74	ring finger protein 13 [Source:MGI Symbol;Acc:MGI:...	[more]
Rnf43	8.703e-13	27.53	ring finger protein 43 [Source:MGI Symbol;Acc:MGI:...	[more]
Rnf43	8.703e-13	27.53	ring finger protein 43 [Source:MGI Symbol;Acc:MGI:...	[more]
Znrf3	1.950e-12	27.56	zinc and ring finger 3 [Source:MGI Symbol;Acc:MGI:...	[more]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q91XF4\|RN167_MOUSE	1.667e-14	28.43	E3 ubiquitin-protein ligase RNF167 OS=Mus musculus...	[more]
sp\|Q5XIL0\|RN167_RAT	1.696e-14	28.43	E3 ubiquitin-protein ligase RNF167 OS=Rattus norve...	[more]
sp\|Q9H6Y7\|RN167_HUMAN	2.296e-14	27.94	E3 ubiquitin-protein ligase RNF167 OS=Homo sapiens...	[more]
sp\|Q0VD51\|RNF13_BOVIN	6.500e-13	23.74	E3 ubiquitin-protein ligase RNF13 OS=Bos taurus OX...	[more]
sp\|O54965\|RNF13_MOUSE	9.394e-13	23.74	E3 ubiquitin-protein ligase RNF13 OS=Mus musculus ...	[more]

BLAST of RING-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2R5LGQ8	2.945e-15	27.75	Putative e3 ubiquitin-protein ligase rnf13 OS=Orni...	[more]
A0A095BT88	6.928e-15	28.26	E3 ubiquitin-protein ligase RNF13 OS=Schistosoma h...	[more]
A0A4Z2DPM2	7.547e-15	32.21	E3 ubiquitin-protein ligase OS=Schistosoma japonic...	[more]
L7M8H2	8.731e-15	27.85	Putative e3 ubiquitin-protein ligase rnf13 OS=Rhip...	[more]
A0A0V1LSV6	1.700e-14	30.46	Stromal cell-derived factor 2 OS=Trichinella nativ...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rnf167	9.598e-15	31.76	ring finger protein 167 [Source:NCBI gene;Acc:1030...	[more]
rnf13	3.804e-14	22.42	ring finger protein 13 [Source:NCBI gene;Acc:10302...	[more]
rnf150a	1.434e-12	23.77	ring finger protein 150 [Source:NCBI gene;Acc:1030...	[more]
rnf24	8.120e-12	38.00	ring finger protein 24 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
rnf150a	9.638e-12	24.06	ring finger protein 150 [Source:NCBI gene;Acc:1030...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000003771.1	1.615e-13	50.00	pep scaffold:Pmarinus_7.0:GL488469:4:5386:-1 gene:...	[more]
rnf150a	2.262e-11	29.66	ring finger protein 150a [Source:ZFIN;Acc:ZDB-GENE...	[more]
si:ch1073-392o20.1	1.100e-9	42.55	ring finger protein 122 [Source:HGNC Symbol;Acc:HG...	[more]
ENSPMAT00000003380.1	1.117e-8	44.00	pep scaffold:Pmarinus_7.0:GL476517:4028:13530:1 ge...	[more]
rnf103	1.363e-7	42.22	ring finger protein 103 [Source:ZFIN;Acc:ZDB-GENE-...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
HRD1	6.914e-7	26.92	Ubiquitin-protein ligase involved in ER-associated...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO36379	1.289e-11	45.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31118	1.231e-10	50.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41758	3.131e-10	25.96	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49283	2.742e-8	40.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36209	6.583e-7	32.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rnf13	6.085e-17	36.94	ring finger protein 13 [Source:NCBI gene;Acc:10116...	[more]
rnf24	1.600e-13	35.90	ring finger protein 24 [Source:NCBI gene;Acc:10116...	[more]
rnf167	6.794e-13	40.28	E3 ubiquitin-protein ligase RNF167 [Source:NCBI ge...	[more]
rnf167	7.141e-13	40.28	E3 ubiquitin-protein ligase RNF167 [Source:NCBI ge...	[more]
rnf24	3.832e-12	35.09	ring finger protein 24 [Source:NCBI gene;Acc:10116...	[more]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000010565.1	0.000e+0	100.00	SMESG000010565.1	[more]
SMESG000013169.1	2.557e-11	37.14	SMESG000013169.1	[more]
SMESG000013169.1	2.849e-11	37.14	SMESG000013169.1	[more]
SMESG000013169.1	3.304e-11	37.14	SMESG000013169.1	[more]
SMESG000016770.1	4.762e-8	32.61	SMESG000016770.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30022428 ID=SMED30022428|Name=RING-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1353bp
GTTGTGAATAAATTCAAATAATAAAATGATTATCTGGTTGGTTGCGATTC
TGTTACAGACAGAATTGGCAGTGTCCAATTACATGATAATTAAAGATTTT
AGCGACGGCCGACGAGTTCTTTACTTGGATATCATCAAGATCAGCCATGA
CCATTGCATGGGACCCATTTTCAATTTGAAAACTCAATCGCTCTGTTATG
AAGAGCACAAACTGGAACTCACGGAAATCTCCGCGAAGCATAAACAGATT
TACGAATTTCTTTCTGTCAACCAGACGAAATCAGAACAATTAAAACCTTG
CTATATGGTCATAGCCCGGTTTACCAGTTGCCCCATCAAGCGTCAAATGC
GCAACGCAAGAACCATGAACTTTGGAACAATCATTTTTATAACAACAAAC
TTGTCCTTATCTCAAGAAATTACGGAATTCGCAGAAAGAGAACCTTCGTC
TACCGTATCGGTGGTTATGATTACCTTAAAGGATGGCCTAAAGCTCCTAA
ATGTAACCAAGAGCAAATTTTGTTACGCTCAACTTTTCTCATATGATTTG
CCTCCAGTGACTCTGATAATTTACGTCTTCGTTTTGGGCGTGGCGGTATT
TGTGACATACTCGATTTACAGATTATTGCGCTCTCTCAGCGTGATTTGGA
TGCGGATCAAGCATTCGGTCAACATGAAGCTATTCATGTCCAAGATGAAA
ATCCAAAGATATCAAGACGGCAATGAGGATTCGTGCGCAATCTGTCTGAT
GGAATTTTCTCAAAACTCCAAATTACGGAAACTTCCTTGTGGGCACGGGT
TTCATTCGAAATGCATTGATCATTGGATTCAAAGCCATAGACCGACTTGT
CCCTTGTGCAATCAAATATTGCCCATTCCATTCGGTATGCCGCATGTCAA
ATGCGCGGTCTGCTCGACTTCCGTGATCGGTAATCACAACAACTCAGCGA
CTTTCTTCGATGACCGGTTCAGTCAAAATACGGTCCTAACAGTGGATTTA
GAAAACATAAATCAAGGGTCTAATAGAACTCGTTTAGCGGATGATATTTC
ATATGAAATGGAGTCAAGTGATCCAAGATCACACAATCCAATGGAGCAAA
ATGAGATCAGAATTGACGGATTTCTGACGTGTGATTTCAACACCCGAAGT
GATGGAATAGTAGAATATCCAAAATCAGTTGAGGTATCCAATGTGACAAC
AAATGACGAAACGGTTTGAATGCCATCAGATCTTGCGTAACTCTTTTACA
CAATTGTCATCACAAGTGCACGTCGACATTCACGCAGTTTCCGTGATCTA
GAATTGACATTTTGACATTCATAATTATTTGATCTATCTAAATATAACTC
ACT

protein sequence of SMED30022428-orf-1

>SMED30022428-orf-1 ID=SMED30022428-orf-1|Name=SMED30022428-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=398bp
MIIWLVAILLQTELAVSNYMIIKDFSDGRRVLYLDIIKISHDHCMGPIFN
LKTQSLCYEEHKLELTEISAKHKQIYEFLSVNQTKSEQLKPCYMVIARFT
SCPIKRQMRNARTMNFGTIIFITTNLSLSQEITEFAEREPSSTVSVVMIT
LKDGLKLLNVTKSKFCYAQLFSYDLPPVTLIIYVFVLGVAVFVTYSIYRL
LRSLSVIWMRIKHSVNMKLFMSKMKIQRYQDGNEDSCAICLMEFSQNSKL
RKLPCGHGFHSKCIDHWIQSHRPTCPLCNQILPIPFGMPHVKCAVCSTSV
IGNHNNSATFFDDRFSQNTVLTVDLENINQGSNRTRLADDISYEMESSDP
RSHNPMEQNEIRIDGFLTCDFNTRSDGIVEYPKSVEVSNVTTNDETV*

Aliases

The feature 'RING-type domain-containing protein' has the following synonyms


Synonym
Smed_02759

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000017	photoreceptor neuron
PLANA:0000020	protonephridia
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR001841	Znf_RING
IPR013083	Znf_RING/FYVE/PHD

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001841	Zinc finger, RING-type	SMART	SM00184	ring_2	coord: 237..278 e-value: 1.6E-8 score: 44.3
IPR001841	Zinc finger, RING-type	PFAM	PF13639	zf-RING_2	coord: 235..279 e-value: 2.8E-13 score: 50.0
IPR001841	Zinc finger, RING-type	PROSITE	PS50089	ZF_RING_2	coord: 237..279 score: 12.725
IPR013083	Zinc finger, RING/FYVE/PHD-type	GENE3D	G3DSA:3.30.40.10		coord: 209..284 e-value: 3.1E-19 score: 70.4
None	No IPR available	PANTHER	PTHR45798	FAMILY NOT NAMED	coord: 220..285
None	No IPR available	CDD	cd16486	mRING-H2-C3H2C2D_ZSWM2	coord: 236..279 e-value: 2.46627E-19 score: 78.8077
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..17 score: 0.727
None	No IPR available	SUPERFAMILY	SSF57850	RING/U-box	coord: 223..289
None	No IPR available	TMHMM	TMhelix		coord: 179..201