Post-GPI attachment to proteins factor 2-like protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30022408 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Human
Match: PGAP2 (post-GPI attachment to proteins 2 [Source:HGNC Symbol;Acc:HGNC:17893]) HSP 1 Score: 141.739 bits (356), Expect = 4.735e-40 Identity = 86/243 (35.39%), Postives = 136/243 (55.97%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 ++TV PL + C L S F + CGV N++PSVS AI G PQRY+WR I LHSAPRFL+A ++N Y + + Y + +LNF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ +S +M +T L+RL+ + ++ + SY +K FI+ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 23 ALVTVCCPLVAFLFCILWSLLFHFKETTATHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLVAFAYWNHYLSCTSPC-----SCYRPLCRLNFGLNVVENLALLVLTYVSSSEDFTIHENAFIVFIASSLGHMLLTCILWRLTKKHTV--SQEDRKSYSWKQRLFIINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 253
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Human
Match: PGAP2 (post-GPI attachment to proteins 2 [Source:HGNC Symbol;Acc:HGNC:17893]) HSP 1 Score: 141.739 bits (356), Expect = 2.705e-39 Identity = 85/240 (35.42%), Postives = 136/240 (56.67%), Query Frame = 3 Query: 78 TVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 ++FP+FG C + S F+ CGV N++PSVS AI G PQRY+WR I LHSAPRFL+A ++N Y + + Y + +LNF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ +S +M +T L+RL+ + ++ + SY +K FI+ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 87 AITFPVFGFFFCIIWSLVFHFEYTVATDCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLVAFAYWNHYLSCTSPC-----SCYRPLCRLNFGLNVVENLALLVLTYVSSSEDFTIHENAFIVFIASSLGHMLLTCILWRLTKKHTV--SQEDRKSYSWKQRLFIINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 314
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Human
Match: PGAP2 (post-GPI attachment to proteins 2 [Source:HGNC Symbol;Acc:HGNC:17893]) HSP 1 Score: 141.739 bits (356), Expect = 2.705e-39 Identity = 85/240 (35.42%), Postives = 136/240 (56.67%), Query Frame = 3 Query: 78 TVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 ++FP+FG C + S F+ CGV N++PSVS AI G PQRY+WR I LHSAPRFL+A ++N Y + + Y + +LNF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ +S +M +T L+RL+ + ++ + SY +K FI+ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 87 AITFPVFGFFFCIIWSLVFHFEYTVATDCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLVAFAYWNHYLSCTSPC-----SCYRPLCRLNFGLNVVENLALLVLTYVSSSEDFTIHENAFIVFIASSLGHMLLTCILWRLTKKHTV--SQEDRKSYSWKQRLFIINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 314
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Human
Match: PGAP2 (post-GPI attachment to proteins 2 [Source:HGNC Symbol;Acc:HGNC:17893]) HSP 1 Score: 141.354 bits (355), Expect = 2.713e-39 Identity = 86/243 (35.39%), Postives = 136/243 (55.97%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 ++TV PL + C L S F + CGV N++PSVS AI G PQRY+WR I LHSAPRFL+A ++N Y + + Y + +LNF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ +S +M +T L+RL+ + ++ + SY +K FI+ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 80 ALVTVCCPLVAFLFCILWSLLFHFKETTATHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLVAFAYWNHYLSCTSPC-----SCYRPLCRLNFGLNVVENLALLVLTYVSSSEDFTIHENAFIVFIASSLGHMLLTCILWRLTKKHTV--SQEDRKSYSWKQRLFIINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 310
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Human
Match: PGAP2 (post-GPI attachment to proteins 2 [Source:HGNC Symbol;Acc:HGNC:17893]) HSP 1 Score: 138.272 bits (347), Expect = 8.011e-39 Identity = 84/234 (35.90%), Postives = 131/234 (55.98%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISS 761 ++TV PL + C L S F + CGV N++PSVS AI G PQRY+WR I LHSAPRFL+A ++N Y + + Y + +LNF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ +S +M +T L+RL+ + + SY +K FI+ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S Sbjct: 23 ALVTVCCPLVAFLFCILWSLLFHFKETTATHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLVAFAYWNHYLSCTSPC-----SCYRPLCRLNFGLNVVENLALLVLTYVSSSEDFTIHENAFIVFIASSLGHMLLTCILWRLTKKHT------DRKSYSWKQRLFIINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS 243
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Celegans
Match: tag-189 (Post-GPI attachment to proteins factor 2 [Source:UniProtKB/Swiss-Prot;Acc:Q22141]) HSP 1 Score: 98.5969 bits (244), Expect = 5.745e-24 Identity = 69/245 (28.16%), Postives = 122/245 (49.80%), Query Frame = 3 Query: 84 SFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGT-SPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQES-EPSTMNKKT 812 P L+IC + S FD+ C V N++PS+SA T +P++YIWR+ I LH PR ++A NF + + P + L +N++EN L+ ++ I S +++ +H K F F + S +YM ++ +L+ + +A T L S+++K+ + +LC Y H YC P ++ F+ EY +SN+ F+ + DF + ++S G + P+ ++K T Sbjct: 22 GLPSSALLICVILSLLLHFDQATSTHCEVANWLPSISAAVSTYTPEKYIWRILIGLHIGPRLVVAIAFRNFLLGS-PLRPLTGHKRLRFLCNLACFLNLLENFFLLALTSISSSEDHSLHAKCFGGFAICSIIYMLLSTWLFNETGRRTA--TNLGQRSHEYKILGAAIFVLCFFLGAYLYWRHNTYCEPGIYTLFALVEYSAVLSNIFFHCTLYYDFHGKNIVLTSSFGGGHYNLLPTQIDKDT 263
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Celegans
Match: tag-189 (Post-GPI attachment to proteins factor 2 [Source:UniProtKB/Swiss-Prot;Acc:Q22141]) HSP 1 Score: 98.5969 bits (244), Expect = 5.745e-24 Identity = 69/245 (28.16%), Postives = 122/245 (49.80%), Query Frame = 3 Query: 84 SFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGT-SPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQES-EPSTMNKKT 812 P L+IC + S FD+ C V N++PS+SA T +P++YIWR+ I LH PR ++A NF + + P + L +N++EN L+ ++ I S +++ +H K F F + S +YM ++ +L+ + +A T L S+++K+ + +LC Y H YC P ++ F+ EY +SN+ F+ + DF + ++S G + P+ ++K T Sbjct: 22 GLPSSALLICVILSLLLHFDQATSTHCEVANWLPSISAAVSTYTPEKYIWRILIGLHIGPRLVVAIAFRNFLLGS-PLRPLTGHKRLRFLCNLACFLNLLENFFLLALTSISSSEDHSLHAKCFGGFAICSIIYMLLSTWLFNETGRRTA--TNLGQRSHEYKILGAAIFVLCFFLGAYLYWRHNTYCEPGIYTLFALVEYSAVLSNIFFHCTLYYDFHGKNIVLTSSFGGGHYNLLPTQIDKDT 263
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Celegans
Match: Y11D7A.9 (pep chromosome:WBcel235:IV:9253979:9256117:-1 gene:WBGene00012433.1 transcript:Y11D7A.9.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y11D7A.9) HSP 1 Score: 48.9062 bits (115), Expect = 1.901e-6 Identity = 59/241 (24.48%), Postives = 105/241 (43.57%), Query Frame = 3 Query: 90 PLFGLIICFLTSSYTQFDKINEI--VCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANW-TKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFK-NFSFNISSPDGTPQESEPSTM 800 P+FG I + D+I+ CG + +PS+S I +R W++F+ H R + ++ Y + V + + Y L L F++ ++E + L G+S I +N +H F F + V+M ++ H S + LSY K+ F L +L T L+ ++ C A+ F+ CEY N+ F+ A D + +F++ + Q +EP+ Sbjct: 55 PMFGSISAIAIALIFHNDEISNYNWQCG-RARLPSLSRIINLPVERTFWQLFLLFHVPIRVVELITGFSRY-KRMRNVNYKRVWLYELSRYLYFVVGLLELIFLSGLSIIGERENIQVHVIFFYVFGICGIVHMISNIF----CHAHSLYYLNPYGRLSYYLKILFTSLYVLSTPILIASFILYWRKCITWAYDVFALCEYSGVFLNICFHGCAFFDIRYKVTFSVRKIEDVVQ-NEPNKQ 288
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Fly
Match: CG7990 (gene:FBgn0030997 transcript:FBtr0074695) HSP 1 Score: 171.014 bits (432), Expect = 7.368e-51 Identity = 96/223 (43.05%), Postives = 135/223 (60.54%), Query Frame = 3 Query: 72 VITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKN 740 V+T PL L CF+T+ Q+D ++E C V N IPS+SAITG SPQRY WR IALH PR IA ++ N+Y + + + + L+ L ++N IE SL GV+YI + +NYP+HE+IFITFMV S YM T+ L + + A ++ ++LS K+K F + +L T GL+ F A HR YC AFSWF+ EY I ++NM F+ + DF + Sbjct: 80 VVTALLPLVTLFTCFVTAYVFQYDDVHETHCRVYNIIPSISAITGVSPQRYFWRFSIALHIGPRIPIAFVYKNYYRSQLRRISPAQVPQTSLLITLILVLNCIEIASLGGVTYISNRENYPVHERIFITFMVCSLCYMLATIKLNGILNAGQA-LSEKQLLSIKWKKILFAVSILSTVGLLVFFAKHRFYCHDLAFSWFAFFEYLIAIANMLFHFTIIWDFPS 301
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Fly
Match: PGAP2 (gene:FBgn0031284 transcript:FBtr0078039) HSP 1 Score: 99.7525 bits (247), Expect = 2.351e-24 Identity = 66/223 (29.60%), Postives = 110/223 (49.33%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGT-SPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDF 734 ++ +S PL G C + S F + C V N++PSVSA G PQ+ +WR+ I LH R +A I+ Y +I R S L+ L +NV+E+L+L +S+ S D+Y H F+ F+ S YM ++ L R + E S ++K N F++ ++ Y H +C +++F+ EY + ++NMGF++++ DF Sbjct: 24 ALVALSLPLGGFFFCVIWSLTFDFVRSTYTHCDVTNYLPSVSAAIGNYEPQKTVWRLAIFLHLPLRLAVAKIYLEHYREHI-------RRSRRLLGILACFLNVVEDLALFCLSFWTSADHYETHRNAFVVFIACSECYMLVSYLLNR--NIQKTVLLPHEEKSLRYKRNLFLVNVIAFGLAGYCFVRHNSHCEAGVYTFFALFEYIVVLTNMGFHMTSYWDF 237
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Zebrafish
Match: pgap2 (post-GPI attachment to proteins 2 [Source:NCBI gene;Acc:541417]) HSP 1 Score: 145.976 bits (367), Expect = 8.958e-42 Identity = 80/232 (34.48%), Postives = 128/232 (55.17%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSP 764 VITV PL GL+ C + + ++ C V N++PS+SA +P+RYIWR I LHSAPRFL+A + +FY F++R + L++ F++ + EN+ L+ ++Y+ S + Y +H+ FI F+ +S +M T L+ L S + EM+SY FK+ F+ C VYF H YC ++ F+ CEY + +SNM F+++A DF +++P Sbjct: 24 AVITVCLPLLGLVACIVLAMLYHYNDATYTHCQVPNYLPSISAAISLTPERYIWRFSIGLHSAPRFLVAAAYLSFYRGR-----FSRRLTEQLLSGFTFLLALSENVGLLLLTYVSSTETYSVHKSGFILFIGSSLFHMLCTCKLWSLIVKYSI--SSEEMMSYWFKLRLFLFNGGCCVLAVYFYRRHNTYCEEGIYTCFAVCEYLVVLSNMAFHMTAYWDFGGKEVMVATP 248
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Mouse
Match: Pgap2 (post-GPI attachment to proteins 2 [Source:MGI Symbol;Acc:MGI:2385286]) HSP 1 Score: 147.517 bits (371), Expect = 1.890e-42 Identity = 87/239 (36.40%), Postives = 135/239 (56.49%), Query Frame = 3 Query: 81 VSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 ++FPLFG C + S F+ CGV N++PSVS AI G PQRY+WR I LHSAPRFL A ++N Y + P Y L+ ++NF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ S YM +T L+RL+ + ++ + SY +K F++ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 25 ITFPLFGFFFCIIWSLVFHFEYTVATDCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLTAFAYWNHYLSCASPCP-----GYRLLCRINFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLGYMLLTCILWRLTKKHTV--SQEDRKSYSWKQRLFVINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 251
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Mouse
Match: Pgap2 (post-GPI attachment to proteins 2 [Source:MGI Symbol;Acc:MGI:2385286]) HSP 1 Score: 145.976 bits (367), Expect = 8.972e-42 Identity = 88/243 (36.21%), Postives = 134/243 (55.14%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 +ITV PL C L S F + CGV N++PSVS AI G PQRY+WR I LHSAPRFL A ++N Y + P Y L+ ++NF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ S YM +T L+RL+ + ++ + SY +K F++ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 23 ALITVCCPLVAFFFCILWSLLFHFKETTSTHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLTAFAYWNHYLSCASPCP-----GYRLLCRINFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLGYMLLTCILWRLTKKHTV--SQEDRKSYSWKQRLFVINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 253
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Mouse
Match: Pgap2 (post-GPI attachment to proteins 2 [Source:MGI Symbol;Acc:MGI:2385286]) HSP 1 Score: 144.05 bits (362), Expect = 4.035e-41 Identity = 88/243 (36.21%), Postives = 132/243 (54.32%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 +ITV PL C L S F + CGV N++PSVS AI G PQRY+WR I LHSAPRFL A ++N Y + P Y L+ ++NF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ S YM +T L+RL+ + + SY +K F++ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 23 ALITVCCPLVAFFFCILWSLLFHFKETTSTHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLTAFAYWNHYLSCASPCP-----GYRLLCRINFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLGYMLLTCILWRLTKKHT------DRKSYSWKQRLFVINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 249
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Mouse
Match: Pgap2 (post-GPI attachment to proteins 2 [Source:MGI Symbol;Acc:MGI:2385286]) HSP 1 Score: 144.05 bits (362), Expect = 4.035e-41 Identity = 88/243 (36.21%), Postives = 132/243 (54.32%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 +ITV PL C L S F + CGV N++PSVS AI G PQRY+WR I LHSAPRFL A ++N Y + P Y L+ ++NF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ S YM +T L+RL+ + + SY +K F++ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 23 ALITVCCPLVAFFFCILWSLLFHFKETTSTHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLTAFAYWNHYLSCASPCP-----GYRLLCRINFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLGYMLLTCILWRLTKKHT------DRKSYSWKQRLFVINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 249
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Mouse
Match: Pgap2 (post-GPI attachment to proteins 2 [Source:MGI Symbol;Acc:MGI:2385286]) HSP 1 Score: 122.094 bits (305), Expect = 4.430e-33 Identity = 74/195 (37.95%), Postives = 109/195 (55.90%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYC 644 +ITV PL C L S F + CGV N++PSVS AI G PQRY+WR I LHSAPRFL A ++N Y + P Y L+ ++NF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ S YM +T L+RL+ + ++ + SY +K F++ I + VYF H +YC Sbjct: 23 ALITVCCPLVAFFFCILWSLLFHFKETTSTHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLTAFAYWNHYLSCASPCP-----GYRLLCRINFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLGYMLLTCILWRLTKKHTV--SQEDRKSYSWKQRLFVINFISFFSALAVYF--RHNMYC 208
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. UniProt/SwissProt
Match: sp|Q9VWK6|PGP2L_DROME (Post-GPI attachment to proteins factor 2-like OS=Drosophila melanogaster OX=7227 GN=CG7990 PE=2 SV=4) HSP 1 Score: 171.014 bits (432), Expect = 7.385e-50 Identity = 96/223 (43.05%), Postives = 135/223 (60.54%), Query Frame = 3 Query: 72 VITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKN 740 V+T PL L CF+T+ Q+D ++E C V N IPS+SAITG SPQRY WR IALH PR IA ++ N+Y + + + + L+ L ++N IE SL GV+YI + +NYP+HE+IFITFMV S YM T+ L + + A ++ ++LS K+K F + +L T GL+ F A HR YC AFSWF+ EY I ++NM F+ + DF + Sbjct: 80 VVTALLPLVTLFTCFVTAYVFQYDDVHETHCRVYNIIPSISAITGVSPQRYFWRFSIALHIGPRIPIAFVYKNYYRSQLRRISPAQVPQTSLLITLILVLNCIEIASLGGVTYISNRENYPVHERIFITFMVCSLCYMLATIKLNGILNAGQA-LSEKQLLSIKWKKILFAVSILSTVGLLVFFAKHRFYCHDLAFSWFAFFEYLIAIANMLFHFTIIWDFPS 301
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. UniProt/SwissProt
Match: sp|Q2ABP2|PGAP2_CRIGR (Post-GPI attachment to proteins factor 2 OS=Cricetulus griseus OX=10029 GN=Pgap2 PE=2 SV=1) HSP 1 Score: 148.673 bits (374), Expect = 4.901e-42 Identity = 90/243 (37.04%), Postives = 135/243 (55.56%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 +ITV PL + C L S F + CGV N++PSVS AI G PQRY+WR I LHSAPRFL A ++N Y + P Y L+ +LNF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ S YM +T L+RL+ + ++ + SY +K FI+ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 23 ALITVCCPLVAFLFCILWSLLFHFKETTSTHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLAAFAYWNHYLSCASPCP-----GYRLLCRLNFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLSYMLLTCILWRLTKKHTV--SQEDRKSYSWKQRLFIINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 253
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. UniProt/SwissProt
Match: sp|Q2ABP3|PGAP2_RAT (Post-GPI attachment to proteins factor 2 OS=Rattus norvegicus OX=10116 GN=Pgap2 PE=2 SV=1) HSP 1 Score: 147.902 bits (372), Expect = 1.091e-41 Identity = 90/243 (37.04%), Postives = 134/243 (55.14%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 +ITV PL C L S F + CGV N++PSVS AI G PQRY+WR I LHSAPRFL A ++N Y + P Y L+ +LNF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ S YM +T L+RL+ + ++ + SY +K FI+ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 23 ALITVCCPLVAFFFCILWSLLFHFKETTSTHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLTAFAYWNHYLSCASPCP-----GYRLLCRLNFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLSYMLLTCILWRLTKKHTV--SQEDRKSYSWKQRLFIINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 253
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. UniProt/SwissProt
Match: sp|Q3TQR0|PGAP2_MOUSE (Post-GPI attachment to proteins factor 2 OS=Mus musculus OX=10090 GN=Pgap2 PE=1 SV=2) HSP 1 Score: 145.976 bits (367), Expect = 6.276e-41 Identity = 88/243 (36.21%), Postives = 134/243 (55.14%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVS-AITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL--ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESE 788 +ITV PL C L S F + CGV N++PSVS AI G PQRY+WR I LHSAPRFL A ++N Y + P Y L+ ++NF +NV+ENL+L+ ++Y+ S +++ +HE FI F+ S YM +T L+RL+ + ++ + SY +K F++ I + VYF H +YC ++ F+ EY + ++NM F+++A DF N I+S P+E Sbjct: 23 ALITVCCPLVAFFFCILWSLLFHFKETTSTHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLTAFAYWNHYLSCASPCP-----GYRLLCRINFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLGYMLLTCILWRLTKKHTV--SQEDRKSYSWKQRLFVINFISFFSALAVYF--RHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITS---QPEEKR 253
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. UniProt/SwissProt
Match: sp|A8KBG2|PGAP2_XENTR (Post-GPI attachment to proteins factor 2 OS=Xenopus tropicalis OX=8364 GN=pgap2 PE=2 SV=1) HSP 1 Score: 143.665 bits (361), Expect = 3.926e-40 Identity = 85/234 (36.32%), Postives = 131/234 (55.98%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSA-ITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPD 767 V TVS PLF + C + S F + C V N++PSVSA I G +PQRYIWR+ I LHSAPRFL+ + ++Y P +Y + LNF++N E LI ++Y+ S +NY +H+ F+ FM+ S YM +T L+R++ S + + ++K ++ F L++ ++ LVY H +YC ++ F+ EY + +SNMGF+++A DF N I SP Sbjct: 22 AVGTVSLPLFAFLFCIVWSLLFNFSETTATHCHVPNYLPSVSAAIGGETPQRYIWRLCIGLHSAPRFLVGVAYLHYYQGTPCSSP-----AYPRLCHLNFLLNCCEIFFLILLTYVSSSENYEVHKLGFMAFMLFSVGYMFVTCSLWRVARKGSGSLEERTSYAWKKRLFGFYLLMFLSSILVYI--WHNMYCEAGVYTVFALLEYLVVLSNMGFHMTAWWDFGNKELMICSPG 248
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. TrEMBL
Match: V4AAH7 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_104796 PE=4 SV=1) HSP 1 Score: 209.149 bits (531), Expect = 1.294e-62 Identity = 105/226 (46.46%), Postives = 146/226 (64.60%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFS 746 V+TVS P L +CF+T+ ++D+IN+ C V NF+PS+SA+TG PQ Y+W++ IALHSAPRF +A I+YN+Y + + +V + + + +NF N IE+ SL+GV+YI + DNYP+HEKIFI FMV S YM + LY + + ++ E S K+KV FI T GL+ F HR YC P AFSWFS CEY IG +NM ++LSA +F+N S Sbjct: 25 AVVTVSLPAVALFLCFVTAVIFRYDEINDTQCNVTNFVPSISAVTGIRPQTYLWKICIALHSAPRFAVAVIYYNYYKDLLYLVSDKYKGLFGFLMTVNFWFNTIEDASLVGVTYISNKDNYPVHEKIFIVFMVLSLCYMLLNTILYYWTR--TGKLSEDEKKSLKWKVAMFIANFTATMGLLAFFIQHRFYCKPLAFSWFSVCEYIIGYTNMAYHLSAYYEFQNMS 248
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. TrEMBL
Match: A0A0P5FP14 (Post-GPI attachment to proteins factor OS=Daphnia magna OX=35525 GN=APZ42_033138 PE=4 SV=1) HSP 1 Score: 207.223 bits (526), Expect = 6.850e-62 Identity = 107/221 (48.42%), Postives = 144/221 (65.16%), Query Frame = 3 Query: 78 TVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKN 740 TVS PL GL+ICF++++ Q + I+E C V N IPS+SAITG SPQRYIWR+ IALH PRFL + +++ FY N + V K+ SYL L +N++E +LIGV+Y+ + +NYP+HEKIFI FMV+S V+M + L L ++ D + E SY FK F L LLCT GL+ F HR+YC AFSWFS EY I +NMGF+ + +DF + Sbjct: 48 TVSLPLIGLVICFVSANIFQQNDIHETHCRVYNVIPSISAITGISPQRYIWRIVIALHVGPRFLTSLVYHRFYLNQLSRVSQLKKKSYLCHVWLALSLNLVEQAALIGVTYVSNRENYPIHEKIFIVFMVSSQVHMLIVLKLLKM--ADFGREQQSEQRSYFFKRCLFFLSLLCTCGLLVFFVKHRVYCHDMAFSWFSFFEYWIAATNMGFHATIIIDFPD 266
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. TrEMBL
Match: B7QH05 (FGF receptor activating protein, putative OS=Ixodes scapularis OX=6945 GN=8041118 PE=4 SV=1) HSP 1 Score: 206.453 bits (524), Expect = 7.642e-62 Identity = 101/244 (41.39%), Postives = 152/244 (62.30%), Query Frame = 3 Query: 75 ITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESEPSTMNK 806 +TV+ PLF L+ CF TS Q+ +N VC V NF PSVSAITG SPQRY+WR +ALH+ PR L+A ++ +Y+ +V +R +L +A+ N+++++ E LSL+GV+Y+ + +NYP+HEKIFI FMV+S +YM T + N T++E S + K++ L L + G++YF HRI+C AFSWFS CEY I + NM F+L+ D + + P G S+P++ ++ Sbjct: 22 LTVALPLFTLVFCFATSMLFQYTAVNTTVCKVYNFCPSVSAITGISPQRYVWRTGVALHTGPRLLLASLYPRYYSRRALLVEAPRRPLFLRLARANYLLHLTEALSLVGVTYVSNRENYPVHEKIFIIFMVSSLLYMVGTCIAANMCQHK--NDTEMEKKSRRLKMSLLGLTLAASAGMLYFFYKHRIHCVELAFSWFSLCEYVICVCNMAFHLTLVYDIPDEELLVGIPLGVANSSKPASKDQ 263
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. TrEMBL
Match: A0A2C9LMH2 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106061446 PE=4 SV=1) HSP 1 Score: 204.527 bits (519), Expect = 7.880e-61 Identity = 108/249 (43.37%), Postives = 150/249 (60.24%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESEPSTMNKKTN 815 V+TVS P L +CF+T+ QFD +NE +C VKNFIPS+SA+TG +PQ Y+WR IALHS PRF + YN Y + V + Y+ + K+NF +N +EN L V+YI + +NYP+HEKIF+ FMVTS YM + L+ S S +++ + +SY +K F I T GL+ +HR+YC AFS FSACEY I +NMG++ +A LDFK+ SF P+ + S+ TN Sbjct: 23 AVVTVSLPGVALFVCFVTAVIFQFDDVNETMCNVKNFIPSISAVTGVTPQTYLWRTCIALHSTPRFAVCLFTYNHYVSRAHSVHPQRLAKYMFLIKVNFWLNFVENSCLTLVAYITNRENYPIHEKIFVVFMVTSLAYMLLNTILFNWSRAGS--FSETDRVSYYWKKVMFASIATATAGLLASFILHRVYCVVGAFSVFSACEYVIAYTNMGYHFTAYLDFKDRSFLFGRLCPYPRNNNESSSLAVTN 269
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. TrEMBL
Match: A0A1S3HX34 (post-GPI attachment to proteins factor 2-like OS=Lingula unguis OX=7574 GN=LOC106158981 PE=4 SV=1) HSP 1 Score: 201.445 bits (511), Expect = 6.371e-60 Identity = 104/224 (46.43%), Postives = 145/224 (64.73%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKN 740 G++TVS P L+ FL D++NE VC NFIPS+SA+TG SP +Y+WR+ IALHSAPRF+IA +HYN+Y + I V + R Y LNF +N +EN L+ VSYI + +NYP+HEKIF+ FMV S YM L+ +S + WT+L++ SY FK +I I++ T L+YF A HR++C P AFSWFS E+ I NM ++++A +FK+ Sbjct: 22 GIVTVSLPAGSLLFSFLWGLIFIPDEVNETVCNCTNFIPSISAVTGVSPGKYVWRICIALHSAPRFIIAVLHYNYYLSLIHNVKPSYRPFYKKFVSLNFWLNTVENACLVLVSYISNRENYPVHEKIFVVFMVMSLCYMLTNTILFNMSRPE--KWTELDLKSYAFKKYLWIAIMISTGVLLYFFAQHRLFCIPGAFSWFSLSEFFIAYINMAYHVTAIWEFKD 243
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Cavefish
Match: pgap2 (post-GPI attachment to proteins 2 [Source:NCBI gene;Acc:103040677]) HSP 1 Score: 142.124 bits (357), Expect = 2.085e-40 Identity = 79/233 (33.91%), Postives = 130/233 (55.79%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL-ILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSP 764 V+TV PL G I C S +++ C V N++PS+SA +P+RYIWR I LHSAPRFL+A ++NFY F+++ L++ F+ + EN+ L+ ++Y+ S + Y +H+ FI F+ +S ++M T L+++ S + EM S ++K+ F+ I LC YF H YC P ++ F+ CEY + +SNM F+++A DF + +++P Sbjct: 24 AVLTVCLPLLGFITCITVSLLYHYNEATYTHCQVYNYLPSISAAISLTPERYIWRFCIGLHSAPRFLLAAAYFNFYRGR-----FSRQLKDQLLSVFTFLCALSENVGLLLLTYVCSTETYSLHKNGFIVFIASSLLHMLCTCRLWQMITKYSVSAE--EMTSCRYKIRLFLFNISLCLLA-GYFFRRHNKYCEPGIYTLFALCEYLVVLSNMAFHMTAFWDFGSKEVMVATP 248
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Cavefish
Match: pgap2 (post-GPI attachment to proteins 2 [Source:NCBI gene;Acc:103040677]) HSP 1 Score: 115.546 bits (288), Expect = 3.143e-30 Identity = 67/197 (34.01%), Postives = 107/197 (54.31%), Query Frame = 3 Query: 69 GVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFIL-ILLCTTGLVYFIAIHRIYCTPNA 656 V+TV PL G I C S +++ C V N++PS+SA +P+RYIWR I LHSAPRFL+A ++NFY F+++ L++ F+ + EN+ L+ ++Y+ S + Y +H+ FI F+ +S ++M T L+++ S + EM S ++K+ F+ I LC YF H YC P + Sbjct: 24 AVLTVCLPLLGFITCITVSLLYHYNEATYTHCQVYNYLPSISAAISLTPERYIWRFCIGLHSAPRFLLAAAYFNFYRGR-----FSRQLKDQLLSVFTFLCALSENVGLLLLTYVCSTETYSLHKNGFIVFIASSLLHMLCTCRLWQMITKYSVSAE--EMTSCRYKIRLFLFNISLCLLA-GYFFRRHNKYCEPGS 212
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Yeast
Match: CWH43 (GPI lipid remodelase; responsible for introducing ceramides into GPI anchors having a C26:0 fatty acid in sn-2 of the glycerol moiety; can also use lyso-GPI protein anchors and various base resistant lipids as substrates; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion [Source:SGD;Acc:S000000610]) HSP 1 Score: 53.5286 bits (127), Expect = 1.974e-8 Identity = 49/191 (25.65%), Postives = 86/191 (45.03%), Query Frame = 3 Query: 171 KNFIPSVSAITGTS-PQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKN 740 + PSVSA G P+R I+++ IAL + PRFL+ HY YL +K+ F++ V+ +S G YI S D++ +H+ IT++V + + M + R S + L + F L ++Y+ H + A+S ++ E+ + + ++ F+ A DFK Sbjct: 46 DEWFPSVSATIGDRYPERSIFQILIALTAFPRFLLLLGHY-----------------YLNQSKVCFLVGVLRTVSCGGWVYITSTDDHDIHDIFMITYIVLTLPWDIM---ITRYS-------SPLTSKNKGLTATIFFGTLFP---MIYWYIQHSVQQRAGAYSIYAYFEWSLILLDIAFDAFAYADFKK 206
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Nematostella
Match: EDO47130 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNE7]) HSP 1 Score: 127.487 bits (319), Expect = 2.327e-35 Identity = 79/234 (33.76%), Postives = 127/234 (54.27%), Query Frame = 3 Query: 75 ITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGT-SPQRYIWRVFIALHSAPRFLIACIHYNFY----NNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISS 761 + + P +IC L S + +D++ + C V N++PS+SA TG SP++YIWR+ IA HS R + ++YNFY ++NI K + + LN + V+ENL+L+ ++Y+ S +NY +HE FITF V++ VYM ++R + T E +S ++KV +L VYF H YC +S F+ CEY +SN+GF+ + ++D +SS Sbjct: 17 LACALPFGSFVICILLSIFLHWDQVTKTHCNVPNYVPSISAATGDFSPEKYIWRIGIAYHSLLRMVFPFVNYNFYKYKASSNI------KSKWFPWLNFLNACVTVVENLALVLLTYVSSSENYSVHEASFITFQVSAMVYMLTNCIIFRWTLSSLP--THQESVSMRWKVICLLLNYSSFAMAVYFFFRHNWYCESGVYSLFALCEYVTVLSNIGFHGTVAIDIGGSLLTLSS 242
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Medaka
Match: PGAP2 (post-GPI attachment to proteins factor 2 [Source:NCBI gene;Acc:101159033]) HSP 1 Score: 131.339 bits (329), Expect = 3.112e-36 Identity = 79/222 (35.59%), Postives = 127/222 (57.21%), Query Frame = 3 Query: 78 TVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLV-YFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKN 740 TVS PL GLI C + SS F+ C V N++PS+SA SP+ YIWR I LHSAPR ++A ++ FY + F+ R ++ LN ++ EN+ L+ ++Y+ S + Y +H++ F+ F+V+S YM +T L++ S N + S+ +KV +L+ LC G +F H +YC ++++F+ EY + +SNM F+L+A DFK+ Sbjct: 27 TVSLPLLGLIACVVISSIFHFEDATGTHCQVPNYLPSISAAISLSPECYIWRFCIGLHSAPRLMVAFTYFRFYK-----ICFDTRFPESPLSCLNLAFSIFENIGLLLLTYVSSSETYFVHKEGFVLFIVSSLTYMLITCRLWKSVKRYSLN--PEDAKSHHWKVR-LLLLNLCFYGFAGFFYWKHNVYCESGSYTFFALFEYLVVISNMAFHLTAMWDFKS 240
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Medaka
Match: pgap2 (post-GPI attachment to proteins factor 2 [Source:NCBI gene;Acc:101163350]) HSP 1 Score: 114.39 bits (285), Expect = 7.008e-30 Identity = 70/221 (31.67%), Postives = 115/221 (52.04%), Query Frame = 3 Query: 72 VITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDF 734 V TV PL L+ C S ++ C V N++PS+S+ P+RYIWR I LHSAPR+L + +++NFY F ++ LL++ L + N+ EN L+ ++Y+ S + Y H+ FI F+ +S ++M +T L+ + N E+ SY +K+ F+ + C Y H +C ++ F+ EY + SNM F+++A DF Sbjct: 25 VATVLLPLTALLACLFISVLYHYEDSTYTHCQVSNYLPSISSAISRVPERYIWRCCIGLHSAPRYLFSVVYFNFYRRR-----FERKLPELLLSGLALLCNIAENSGLLLLTYVSSTETYSYHKNGFIVFVGSSLLHMLVTCRLWFVLKRQYLN--PEEVTSYVWKLRLFLFNISCCGAAAYCFRRHNKFCEDGVYTVFAFFEYMVVFSNMAFHMTAFWDF 238
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Medaka
Match: PGAP2 (post-GPI attachment to proteins factor 2 [Source:NCBI gene;Acc:101159033]) HSP 1 Score: 86.2705 bits (212), Expect = 1.574e-19 Identity = 61/186 (32.80%), Postives = 99/186 (53.23%), Query Frame = 3 Query: 168 VKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLV-YFIAIHRIYCTPNAFSWFSACEYGIG--MSNMGFNL 716 V N++PS+SA SP+ YIWR I LHSAPR ++A ++ FY + F+ R ++ LN ++ EN+ L+ ++Y+ S + Y +H++ F+ F+V+S YM +T L++ S N + S+ +KV +L+ LC G +F H +YC S EY + +S M NL Sbjct: 40 VPNYLPSISAAISLSPECYIWRFCIGLHSAPRLMVAFTYFRFYK-----ICFDTRFPESPLSCLNLAFSIFENIGLLLLTYVSSSETYFVHKEGFVLFIVSSLTYMLITCRLWKSVKRYSLN--PEDAKSHHWKVR-LLLLNLCFYGFAGFFYWKHNVYCE-------SGSEYHLSSFISPMTLNL 210
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Planmine SMEST
Match: SMESG000044614.1 (SMESG000044614.1) HSP 1 Score: 478.404 bits (1230), Expect = 1.157e-172 Identity = 253/267 (94.76%), Postives = 253/267 (94.76%), Query Frame = 3 Query: 15 MTLCKKXXXXXXXXXXXXGVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESEPSTMNKKTN 815 MTLCKKNVNLFNLPFNVLGVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFM RLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESEPSTMNKKTN Sbjct: 1 MTLCKKNVNLFNLPFNVLGVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFM--------------RLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFSFNISSPDGTPQESEPSTMNKKTN 253
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Planmine SMEST
Match: SMESG000051249.1 (SMESG000051249.1) HSP 1 Score: 139.043 bits (349), Expect = 2.096e-39 Identity = 80/211 (37.91%), Postives = 119/211 (56.40%), Query Frame = 3 Query: 108 ICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHSAPRFLIACIHYNFY---NNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLD 731 ICFL S FD +N C N +PS+SAITG PQ YIWR IALH+ PRFLIA + FY + + + N N + N +N++E SL+ ++ + S++N+ +H F+ F +TS ++M ++LY+ R+ + N EM SY K + +LC+ G+ +F HR+YCTP +S FS EY + NMGF+ A+ D Sbjct: 23 ICFLISVLFYFDIVNRTDCRAINILPSISAITGHRPQIYIWRFGIALHAVPRFLIAYTYRQFYLDKSTKLFLGIINHSNWLFHLINFNMWVNILEIFSLLALTVVSSVENFYIHSLFFVGFAITSILHMVISLYISRVFY---INQDLSEMKSYHQKCFCLAVTILCSLGMAFFFTKHRLYCTPYDYSKFSLLEYIFVLINMGFHYIATFD 230
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Planmine SMEST
Match: SMESG000044614.1 (SMESG000044614.1) HSP 1 Score: 110.923 bits (276), Expect = 2.738e-30 Identity = 69/80 (86.25%), Postives = 71/80 (88.75%), Query Frame = 3 Query: 15 MTLCKKXXXXXXXXXXXXGVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQRYIWRVFIALHS 254 MTLCKKNVNLFNLPFNVLGVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQ + +H Sbjct: 1 MTLCKKNVNLFNLPFNVLGVITVSFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGTSPQSNARKDIYNIHG 80 HSP 2 Score: 88.5817 bits (218), Expect = 7.373e-22 Identity = 41/42 (97.62%), Postives = 42/42 (100.00%), Query Frame = 2 Query: 434 NARKDIYNIHGDVLRIYGNDPLFVQIISRGFRQLDETGNAFL 559 NARKDIYNIHGDVLRIYGNDPLFV+IISRGFRQLDETGNAFL Sbjct: 70 NARKDIYNIHGDVLRIYGNDPLFVEIISRGFRQLDETGNAFL 111
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Planmine SMEST
Match: SMESG000002779.1 (SMESG000002779.1) HSP 1 Score: 55.8398 bits (133), Expect = 5.661e-9 Identity = 66/222 (29.73%), Postives = 96/222 (43.24%), Query Frame = 3 Query: 84 SFPLFGLIICFLTSSYTQFDKINEIVCGVKNFIPSVSAITGT-SPQRYIWRVFIALHSAPRFLIACIHYNFYNNNIDVVPFNKRNSYLLIAKLNFIINVIENLSLIGVSYIPSIDNYPMHEKIFITFMVTSCVYMAMTLYLYRLSHGDSANWTKLEMLSYKFKVNFFILILLCTTGLVYFIAIHRIYCTPNAFSWFSACEYGIGMSNMGFNLSASLDFKNFS 746 S L +C S Y FD++N C V NF+PS SA G Q IW+ R I Y Y ++ P K NS + I IIN IE +SLI +S S Y +H+ FITF++ S V+ +Y R N+ + + + ++ I ILL V IH I C +S F EY + +N+ F+ + + + S Sbjct: 14 SLQLLACFLCVFLSMYYNFDEVNNTHCHVSNFLPSFSAAVGNYELQLTIWQYVTVPVCLFRLFIL---YLVYICWLEKYP--KANSIITIMT---IINFIEIVSLISLSIFSSSRYYDIHKISFITFLLMSIVFQVFNVYFSRKYQKIENNFLRRSICT-----SYMISILLAGLSFV----IHNILCISYVYSVFGLSEYILITTNVVFHTLVAKEIDSLS 218 The following BLAST results are available for this feature:
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 3
BLAST of Post-GPI attachment to proteins factor 2-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 4
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30022408 ID=SMED30022408|Name=Post-GPI attachment to proteins factor 2-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=913bpback to top protein sequence of SMED30022408-orf-1 >SMED30022408-orf-1 ID=SMED30022408-orf-1|Name=SMED30022408-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=268bp MTLCKKNVNLFNLPFNVLGVITVSFPLFGLIICFLTSSYTQFDKINEIVCback to top Annotated Terms
The following terms have been associated with this transcript:
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