Transient receptor potential cation channel subfamily A member 1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30022407 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Human
Match: TRPA1 (transient receptor potential cation channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:497]) HSP 1 Score: 187.963 bits (476), Expect = 6.794e-48 Identity = 226/962 (23.49%), Postives = 413/962 (42.93%), Query Frame = 2
Query: 329 NINK----KSCKGSTALLL--AVKSGNAECVRLICKQKGMEI-DGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLL-HAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNS---------KINIASVINSTDC----------EGYSC-----FLN---------AIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSL----SVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMR-NHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEF---RFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSAS-------VNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIM-----SMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAK--VKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFK---IFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
N NK K C L A G E + I + +E+ D G TP+ A N I+ VK LL GANP ++ M LH ++ + E++K+LL H ++ NG + + +A + EA + ++ I+ A+ S +C GYS F+N A++ +I CL GA I+ + A+H A+ G +EI+ + + + N D +H SL +A+ L+ A +N + +PL+ + S + LLL+ A V +KD + LHL + + L + ++ ++ + L+ D++G PLH AC N L+ ++ + ++ P+H A G + + L+ +I + NE + + + LA ++GH + + L K + D G L +A G +K+IL + R + +T LH AA+ G K V LLS A++ N + L LAL N+ + W ++ K + +I + LL+ + ++ S +Y+F L P + + T + + + +L+ HP+ LL KW +G M +L ++ L T ++ + P +A +++ G + S +++ T+S + ++ S+FG+ + E+ + QK YF SN + ++Y++ I F V+ P +QW G IA+ W N + YLQ N GI I+M + ++ ++++ ++F+ L++ + ++FYI+ Q PF + S + + M++G+++Y FL+P + + + F+I + I L+NL++G+AVGDI + A + +Q+ + E LP
Sbjct: 49 NFNKQKKLKRCDDMDTFFLHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLKKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILAT-------ASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPY-GLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQ-DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL-LKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEVVLTIIRSKRWDECLKIFSHNSPGNKCPITEMIEYLPECMKVLLDFCMLHSTEDKSCRDYYIEYNFKYLQC-PLEFTKKTPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEYLLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMA----FNSTGIINETSDHSEILDTTNSYLIKTCMILVFLSSIFGYCK---EAGQIFQQKRNYFMDISNVLEWIIYTTGIIFVLPLFVEIP-AHLQWQCGAIAVYFYWMNFLLYLQRFENCGIFIVMLEVILKTLLRSTVVFIFLLLAFGLSFYILLNLQDPFSSPLLSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLP 991 HSP 2 Score: 105.531 bits (262), Expect = 2.750e-22 Identity = 115/475 (24.21%), Postives = 194/475 (40.84%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDG-----------------------------------------MCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHL------GIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGH 1549
LH A E ++F+LS+ N N ++ L +AV+ N E ++++ + + ++++ + G T + +AC N + ++ILL GA P KS G LH +++ LEMIK+ L + + + I AA+ G E L I S S ++N+TD + A + + + GADIN +EG++ L +A+ I+ L G ++ DN + LHL G+ N + + ++ N TPL + V L F N + K K K++ LH + G I T + L Q I + LLN D +G PLH+A N K+ L+ +GA L L ++N +H A+ G+ + +K ++D N++ +ED + A + GH
Sbjct: 102 LHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLKKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGS----VDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILATASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDG-CTPLHYACRQGGPGSVNNLLGF-------NVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTR---LLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGH 560 HSP 3 Score: 69.3218 bits (168), Expect = 3.656e-11 Identity = 66/277 (23.83%), Postives = 124/277 (44.77%), Query Frame = 2
Query: 263 LLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACR------------LNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN-INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHV 1054
+LH A++ + EL ++++S +INK +G + L+LA S + V L+ KG ++D +D G+ + L + + M I +++ M + DG LH+ R + LL S K + SP+ AAS G + +Q + ++++ +N D G + A + ++ LK GA + L+ + G ALH AS G+++ + + D + + +D + ++ALH G LL ++A +
Sbjct: 312 MLHRASLFDHHELADYLISVGADINKIDSEGRSPLILATASASWNIVNLLL-SKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELV-------MDEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRL-----LNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADI 574
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Human
Match: TRPA1 (transient receptor potential cation channel subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:497]) HSP 1 Score: 169.859 bits (429), Expect = 1.883e-42 Identity = 202/903 (22.37%), Postives = 383/903 (42.41%), Query Frame = 2
Query: 407 LICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLH--------AKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSL----SVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMR-NHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEF---RFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSAS-------VNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIM-----SMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAK--VKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFK---IFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
++ + + ++++ + G T + +AC N + ++ILL GA P KS G +H S E ++++L + +N +P+ LA G LE +I CL GA I+ + A+H A+ G +EI+ + + + N D +H SL +A+ L+ A +N + +PL+ + S + LLL+ A V +KD + LHL + + L + ++ ++ + L+ D++G PLH AC N L+ ++ + ++ P+H A G + + L+ +I + NE + + + LA ++GH + + L K + D G L +A G +K+IL + R + +T LH AA+ G K V LLS A++ N + L LAL N+ + W ++ K + +I + LL+ + ++ S +Y+F L P + + T + + + +L+ HP+ LL KW +G M +L ++ L T ++ + P +A +++ G + S +++ T+S + ++ S+FG+ + E+ + QK YF SN + ++Y++ I F V+ P +QW G IA+ W N + YLQ N GI I+M + ++ ++++ ++F+ L++ + ++FYI+ Q PF + S + + M++G+++Y FL+P + + + F+I + I L+NL++G+AVGDI + A + +Q+ + E LP
Sbjct: 1 VLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLKKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLE-----------------------------------------MIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILAT-------ASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPY-GLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQ-DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL-LKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEVVLTIIRSKRWDECLKIFSHNSPGNKCPITEMIEYLPECMKVLLDFCMLHSTEDKSCRDYYIEYNFKYLQC-PLEFTKKTPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEYLLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMA----FNSTGIINETSDHSEILDTTNSYLIKTCMILVFLSSIFGYCK---EAGQIFQQKRNYFMDISNVLEWIIYTTGIIFVLPLFVEIP-AHLQWQCGAIAVYFYWMNFLLYLQRFENCGIFIVMLEVILKTLLRSTVVFIFLLLAFGLSFYILLNLQDPFSSPLLSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLP 843 HSP 2 Score: 96.2857 bits (238), Expect = 1.927e-19 Identity = 106/421 (25.18%), Postives = 183/421 (43.47%), Query Frame = 2
Query: 329 NINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEY-------DGMCC-LHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHL------GIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGH 1549
++N + G+TA+++A + N+E ++++ K KG + ++ G PI A + ++I+L +G S +G LH +++ LEMIK+ L + + + I AA+ G E L I S S ++N+TD + A + + + GADIN +EG++ L +A+ I+ L G ++ DN + LHL G+ N + + ++ N TPL + V L F N + K K K++ LH + G I T + L Q I + LLN D +G PLH+A N K+ L+ +GA L L ++N +H A+ G+ + +K ++D N++ +ED + A + GH
Sbjct: 9 DVNLEGENGNTAVIIACTTNNSEALQILLK-KGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGS----VDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILATASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDG-CTPLHYACRQGGPGSVNNLLGF-------NVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTR---LLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGH 412 HSP 3 Score: 68.1662 bits (165), Expect = 7.651e-11 Identity = 66/278 (23.74%), Postives = 124/278 (44.60%), Query Frame = 2
Query: 260 NLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACR------------LNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN-INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHV 1054
+LH A++ + EL ++++S +INK +G + L+LA S + V L+ KG ++D +D G+ + L + + M I +++ M + DG LH+ R + LL S K + SP+ AAS G + +Q + ++++ +N D G + A + ++ LK GA + L+ + G ALH AS G+++ + + D + + +D + ++ALH G LL ++A +
Sbjct: 163 TMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILATASASWNIVNLLL-SKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELV-------MDEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRL-----LNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADI 426
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]) HSP 1 Score: 169.474 bits (428), Expect = 4.686e-42 Identity = 139/510 (27.25%), Postives = 232/510 (45.49%), Query Frame = 2
Query: 257 FNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE 1786
F LH AA N + +L++ ++ + G T L +A K GN V+L+ +G +ID + R G TP+ A R +V++LL GA + +G+ LH + +H+E +K LL K + + ++ + +AA G+ L + N S + + LN I+L L+ GA ++ G+ ALH+A+ G E++ L NG +++ + LH+ G + + LL + AH + N TPL SA E + +LL A L KK T LH+ G ++ +LL Q ++ +S NG PLH+A N +I + L++ GA + P+H A+++GH ++V L+D I + + + LA Q N+ + L + + + G L+ AC G++ MV +LK+ N+ + + TPLHQAAQ G T ++ LL GA+
Sbjct: 189 FTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLL-DRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALSGLTPIHVAAFMGHLN--------IVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAR-------EGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQ------RRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGAN-IHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAK 675 HSP 2 Score: 132.109 bits (331), Expect = 1.561e-30 Identity = 150/600 (25.00%), Postives = 255/600 (42.50%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGA---EMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE-DIANELLNRGLEVISDTNSVNKSLTKYHF 2038
N N LH AA + L++ +L + +++ + KG+TAL +A +G AE V+++ K+ G I+ Q + G TP+ +A + N ID+VK LL GAN + DG L ++ H + + +LL +V+ + + +AA ++ L +Q+ N+ + S G++ A Y + L GA ++ G LH+AS+ G + ++ L D G I++ + + LH +G V E LL A + +N L+PL ++ +Q + + L DV L T LH+ GH +LL +K+ N+ +G P+HVA I L+ GA+ + N +H A R G +E+V+ L+ N + R +E + +A + G I + L + G L + + G + + ++L+ + TPLH AA+ G + + LL A +N + TPL +A A LN N + K G T + + D+ LL++G + T S LT H
Sbjct: 26 NGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKE-GANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVR----LPALHIAARKDDTKSAALLLQNDHNADVQSKS--------GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPL----HMAAQGDHVECVKHLLQHKAPVDDVTL---DYLTALHVAAHCGHYRVTKLLL------DKRANPNARALSGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLR-NGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGY--TPLHIAAKKNQMQIASTLLNYGAETNIVT---KQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKS---GLTSLHL 590 HSP 3 Score: 112.464 bits (280), Expect = 1.933e-24 Identity = 127/530 (23.96%), Postives = 217/530 (40.94%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL----------CDNG---ININSVDNNLDSA--------------------LHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLF-----------------QLIKEEEK---QFLLNSYDDNGDY-------PLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMV 1660
N LH A+ N +++ +L + I+ K+ G T L A +SG+ + V L+ ++G + + + G +P+ +A + + ++ VK LL + A D + LH H + KLLL + +P + +G++PI +AA +G+L L +Q+ + + T+ G + A R Q ++ L+ GA ++ E + LHIAS +G +EI+ L NG ++I++ + +D A LH+ GSL VA+ LL A + +N TPL +A +Q+ + +L LN A+ + K+ T LHL GH + + LL L +E+K +L + + D PL VAC K+ N+L+ +GAN+ N P+H+A Q GH +I L + ++ GN L A ++G I +V
Sbjct: 220 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL-ERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALSGLTPIHVAAFMGHLNIVLLLLQNGASPDV--------TNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGYTPLHIAAKK-NQMQIASTL------LNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQA----------------------------------AQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 699 HSP 4 Score: 97.8265 bits (242), Expect = 7.311e-20 Identity = 122/501 (24.35%), Postives = 218/501 (43.51%), Query Frame = 2
Query: 374 AVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIR--YKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFL 1867
A ++GN + V K G++I+ ++ G + LA + + +V+ LL G++ + G LH + E++K+L+ + + NG +P+ +AA +++ ++ L+ + N ++ +G++ A++ + Q IL + L ALHIA+ ++ L N N + + + LH+ H G+++VA LL A V+ RN +TPL ++ S+ G + +KLLL+ + K + T LH SGH + +ELL E+ L + NG PLH+A + + +L+ A + + +H A GH + K L+D R I +A GH NI L + G L A + G + +V+ +L+ + R + TPLH A++ G+T++V+ LL A T + TPL ++ + A V L
Sbjct: 1 AARAGNLDKVVEYLK-GGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHID----VVKYLLENGANQSTATE----DGFTPLAVALQQGHNQAVAILLENDTKGKVRLP------ALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPL----HVASKRG---NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL------ERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANP-NARALSGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLL 472 HSP 5 Score: 91.6633 bits (226), Expect = 5.298e-18 Identity = 99/396 (25.00%), Postives = 167/396 (42.17%), Query Frame = 2
Query: 797 AIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ---------------LIKEEEKQ-FLLNSYDDNGDY-------PLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKT 1912
A R ++E LK G DIN G NALH+A++ G ++ +L G +++S ++ALH+ G V + L+ A++N ++N TPL +A E + +K LL N A+ + T L + + GH + + +L + K++ K LL D N D PLH+A + L++ GA + N P+H A+++G+ +VK L+D QI + D + A +SGH + E L + + ++ + G + L A Q + VK +L+ + T LH AA G ++ + LL A TP+ +A H N + L + + R +T
Sbjct: 1 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQ-------ENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG-GQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALSGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGET 388 HSP 6 Score: 67.0106 bits (162), Expect = 1.890e-10 Identity = 61/260 (23.46%), Postives = 106/260 (40.77%), Query Frame = 2
Query: 242 HPN----NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAAS----------------------LGYLEAFYLCIQS---LMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL 934
HP+ N + LH +A ++ +L + + KG T L +A K G+ + +L+ +++ D + G TP+ +A + N + I LL YGA G+ LH + H +M+ LLL + + +G++ + LAA LGY C ++N + + +N+ GY+ A + II L++GA N G AL IA +G+ ++ L
Sbjct: 444 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAA-ADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 702
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]) HSP 1 Score: 169.859 bits (429), Expect = 7.639e-42 Identity = 135/512 (26.37%), Postives = 234/512 (45.70%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE 1786
N LH A+ N +++ +L + I+ K+ G T L A +SG+ + V L+ ++G + + + G +P+ +A + + ++ VK LL + A D + LH H + KLLL + +P + NG +P+ +A ++ L ++ + + S + + LN I+L L+ GA ++ G+ ALH+A+ G E++ L NG +++ + LH+ G + + LL + AH + N TPL SA Q+ V L L A L KK T LH+ G ++ +LL Q ++ +S NG PLH+A N +I + L++ GA + P+H A+++GH ++V L+D I + + + LA Q N+ + L + + + G L+ AC G++ MV +LK+ N+ + + TPLHQAAQ G T ++ LL GA+
Sbjct: 236 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL-ERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLN--------IVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISARE-GQVDVASVL------LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQ------RRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKG-ANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAK 724 HSP 2 Score: 155.221 bits (391), Expect = 2.513e-37 Identity = 165/607 (27.18%), Postives = 268/607 (44.15%), Query Frame = 2
Query: 230 IDENHPN-NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE-DIANELLNRGLEVISDTNSVNKS-LTKYHF 2038
ID N N N N LH AA + L++ +L + +++ + KG+TAL +A +G AE V+++ K+ G I+ Q + G TP+ +A + N ID+VK LL GAN + DG L ++ H + + +LL +V+ + + +AA ++ L +Q+ N+ + S G++ A Y + L GA ++ G LH+AS+ G + ++ L D G I++ + + LH +G V E LL A + +N L+PL ++ +Q + + L DV L T LH+ GH +LL +K+ N+ NG PLH+AC N K+ L+ GA++ + PIH A GHL IV L+ N + N + +A ++G + L + ++ L A ++G +V+L+L+ + + TPLH +A+ GQ + LL GA T TPL +A + AK+ L ++ K G T + KN+ IA+ LLN G E TN V K +T H
Sbjct: 34 IDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKE-GANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVR----LPALHIAARKDDTKSAALLLQNDHNADVQSKS--------GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPL----HMAAQGDHVECVKHLLQHKAPVDDVTL---DYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ-NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAG---KNGYTPLHIAAKKNQMQIASTLLNYGAE----TNIVTKQGVTPLHL 606 HSP 3 Score: 114.39 bits (285), Expect = 7.843e-25 Identity = 112/465 (24.09%), Postives = 192/465 (41.29%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMV 1660
LH AA + + + +L K+ N N ++ G T L +A K + + L+ K G I G TPI +A + ++IV +LL GA+P + G LH R+ +E+++ LL + + +P+ +A+ LG E L +Q + + ++ GY+ + R Q + L+ GA +LA +G LH+A++ G ++ L +S N + LH+ + +A LL A N+ + +TPL +L SQ G + L L+ A++ + K T LHL + ++L + +++ L G PL VAC K+ N+L+ +GAN+ N P+H+A Q GH +I L + ++ GN L A ++G I +V
Sbjct: 340 LHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKY-GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHP--------DAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPL----HLASQEGHTDMVTLL---LDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKL------GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAA----------------------------------QQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 748 HSP 4 Score: 99.7525 bits (247), Expect = 2.663e-20 Identity = 108/440 (24.55%), Postives = 182/440 (41.36%), Query Frame = 2
Query: 782 SCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ---------------LIKEEEKQ-FLLNSYDDNGDY-------PLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG----------------NNILMYACQVGDIGM-----------------VKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMG 1930
+ FL A R ++E LK G DIN G NALH+A++ G ++ +L G +++S ++ALH+ G V + L+ A++N ++N TPL +A E + +K LL N A+ + T L + + GH + + +L + K++ K LL D N D PLH+A + L++ GA + N P+H A+++G+ +VK L+D QI + D + A +SGH + E L + + ++ + G ++L + V D+ + KL+L K N R + TPLH A + + K++E L+ GA + T TP+ +A H N + L + + R +T HM
Sbjct: 12 ASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQ-------ENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG-GQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETA-LHMA 442 HSP 5 Score: 99.3673 bits (246), Expect = 3.318e-20 Identity = 120/494 (24.29%), Postives = 219/494 (44.33%), Query Frame = 2
Query: 356 STALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIR--YKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTF-HQTPLTLA 1828
+ + L A ++GN + V K G++I+ ++ G + LA + + +V+ LL G++ + G LH + E++K+L+ + + NG +P+ +AA +++ ++ L+ + N ++ +G++ A++ + Q IL + L ALHIA+ ++ L N N + + + LH+ H G+++VA LL A V+ RN +TPL ++ S+ G + +KLLL+ + K + T LH SGH + +ELL E+ L + NG PLH+A + + +L+ A + + +H A GH + K L+D R + + +A + + E L + + E+G + A +G + +V L+L+ + + N T LH AA+AGQ ++V LL GA + QTPL +A
Sbjct: 11 NASFLRAARAGNLDKVVEYLK-GGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDV----VKYLLENGANQSTATE----DGFTPLAVALQQGHNQAVAILLENDTKGKVRLP------ALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPL----HVASKRG---NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL------ERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANP-NARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIA 475 HSP 6 Score: 68.5514 bits (166), Expect = 7.661e-11 Identity = 61/260 (23.46%), Postives = 106/260 (40.77%), Query Frame = 2
Query: 242 HPN----NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAAS----------------------LGYLEAFYLCIQ---SLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL 934
HP+ N + LH +A ++ +L + + KG T L +A K G+ + +L+ +++ D + G TP+ +A + N + I LL YGA G+ LH + H +M+ LLL + + +G++ + LAA LGY C ++N + + +N+ GY+ A + II L++GA N G AL IA +G+ ++ L
Sbjct: 493 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA-DSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 751
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]) HSP 1 Score: 169.859 bits (429), Expect = 7.643e-42 Identity = 135/512 (26.37%), Postives = 234/512 (45.70%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE 1786
N LH A+ N +++ +L + I+ K+ G T L A +SG+ + V L+ ++G + + + G +P+ +A + + ++ VK LL + A D + LH H + KLLL + +P + NG +P+ +A ++ L ++ + + S + + LN I+L L+ GA ++ G+ ALH+A+ G E++ L NG +++ + LH+ G + + LL + AH + N TPL SA Q+ V L L A L KK T LH+ G ++ +LL Q ++ +S NG PLH+A N +I + L++ GA + P+H A+++GH ++V L+D I + + + LA Q N+ + L + + + G L+ AC G++ MV +LK+ N+ + + TPLHQAAQ G T ++ LL GA+
Sbjct: 244 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL-ERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLN--------IVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISARE-GQVDVASVL------LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQ------RRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKG-ANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAK 732 HSP 2 Score: 163.696 bits (413), Expect = 6.714e-40 Identity = 166/607 (27.35%), Postives = 271/607 (44.65%), Query Frame = 2
Query: 230 IDENHPN-NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE-DIANELLNRGLEVISDTNSVNKS-LTKYHF 2038
ID N N N N LH AA + L++ +L + +++ + KG+TAL +A +G AE V+++ K+ G I+ Q + G TP+ +A + N ID+VK LL GAN + DG L ++ H + + +LL +V+ + + +AA ++ L +Q+ N+ + ++N T G++ A Y + L GA ++ G LH+AS+ G + ++ L D G I++ + + LH +G V E LL A + +N L+PL ++ +Q + + L DV L T LH+ GH +LL +K+ N+ NG PLH+AC N K+ L+ GA++ + PIH A GHL IV L+ N + N + +A ++G + L + ++ L A ++G +V+L+L+ + + TPLH +A+ GQ + LL GA T TPL +A + AK+ L ++ K G T + KN+ IA+ LLN G E TN V K +T H
Sbjct: 34 IDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKE-GANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVR----LPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPL----HMAAQGDHVECVKHLLQHKAPVDDVTL---DYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ-NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAG---KNGYTPLHIAAKKNQMQIASTLLNYGAE----TNIVTKQGVTPLHL 614 HSP 3 Score: 114.39 bits (285), Expect = 7.846e-25 Identity = 112/465 (24.09%), Postives = 192/465 (41.29%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMV 1660
LH AA + + + +L K+ N N ++ G T L +A K + + L+ K G I G TPI +A + ++IV +LL GA+P + G LH R+ +E+++ LL + + +P+ +A+ LG E L +Q + + ++ GY+ + R Q + L+ GA +LA +G LH+A++ G ++ L +S N + LH+ + +A LL A N+ + +TPL +L SQ G + L L+ A++ + K T LHL + ++L + +++ L G PL VAC K+ N+L+ +GAN+ N P+H+A Q GH +I L + ++ GN L A ++G I +V
Sbjct: 348 LHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKY-GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHP--------DAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPL----HLASQEGHTDMVTLL---LDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKL------GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAA----------------------------------QQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 756 HSP 4 Score: 99.3673 bits (246), Expect = 3.024e-20 Identity = 104/448 (23.21%), Postives = 185/448 (41.29%), Query Frame = 2
Query: 782 SCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ--------------------------LIKEE-----EKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG----------------NNILMYACQVGDIGM-----------------VKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMG 1930
+ FL A R ++E LK G DIN G NALH+A++ G ++ +L G +++S ++ALH+ G V + L+ A++N ++N TPL +A E + +K LL N A+ + T L + + GH + + +L + L++ + + + ++N ++G PLH+A + L++ GA + N P+H A+++G+ +VK L+D QI + D + A +SGH + E L + + ++ + G ++L + V D+ + KL+L K N R + TPLH A + + K++E L+ GA + T TP+ +A H N + L + + R +T HM
Sbjct: 12 ASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQ-------ENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG-GQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETA-LHMA 450 HSP 5 Score: 96.2857 bits (238), Expect = 2.656e-19 Identity = 121/502 (24.10%), Postives = 220/502 (43.82%), Query Frame = 2
Query: 356 STALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIR--YKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN--------INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTF-HQTPLTLA 1828
+ + L A ++GN + V K G++I+ ++ G + LA + + +V+ LL G++ + G LH + E++K+L+ + + NG +P+ +AA +++ ++ L+ + N ++ +G++ A++ + Q IL + L ALHIA+ ++ L N N +N + + LH+ H G+++VA LL A V+ RN +TPL ++ S+ G + +KLLL+ + K + T LH SGH + +ELL E+ L + NG PLH+A + + +L+ A + + +H A GH + K L+D R + + +A + + E L + + E+G + A +G + +V L+L+ + + N T LH AA+AGQ ++V LL GA + QTPL +A
Sbjct: 11 NASFLRAARAGNLDKVVEYLK-GGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDV----VKYLLENGANQSTATE----DGFTPLAVALQQGHNQAVAILLENDTKGKVRLP------ALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPL----HVASKRG---NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL------ERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANP-NARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIA 483 HSP 6 Score: 68.5514 bits (166), Expect = 7.662e-11 Identity = 61/260 (23.46%), Postives = 106/260 (40.77%), Query Frame = 2
Query: 242 HPN----NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAAS----------------------LGYLEAFYLCIQ---SLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL 934
HP+ N + LH +A ++ +L + + KG T L +A K G+ + +L+ +++ D + G TP+ +A + N + I LL YGA G+ LH + H +M+ LLL + + +G++ + LAA LGY C ++N + + +N+ GY+ A + II L++GA N G AL IA +G+ ++ L
Sbjct: 501 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA-DSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 759
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Celegans
Match: trpa-1 (Transient receptor potential cation channel subfamily A member 1 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q18297]) HSP 1 Score: 182.185 bits (461), Expect = 1.820e-46 Identity = 232/1106 (20.98%), Postives = 454/1106 (41.05%), Query Frame = 2
Query: 248 NNTFNLLHEAAISKNPELLEFILSKKP-NINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRL--NMIDIVKILLYYGANPMK-----------------SEYD-----GMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIA-------SVINSTDCEGYSCFL---------------NAIRYKQRTIILECLKYGADINLA---QNEGKNA----------LHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHA-HVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLF-----------------------QLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEM-YENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTM---------EFRFKTG---KTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLD--------------------AGPYD-----SASVNSRYTEFMTIAKYRKEKLIL---------HPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIA--------DSPDYD-NQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCT------IQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYF----LDPGFKIF----TAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQ-----AKFYEPVFVYKQMRRSVFQRFFS 3088
+N +++H++A N L+ L K P +N + T L A + GN + V+L+ + + + ++R+G TP+ +A + DI I+ A+ + +E D + LH+ ++ + L+ K + +D+N ++P+ LA G E IQ L+ + N+ +V + G +L N +++T + ++ L Q E KN+ +H A+E G+ E++ L + G N N ++ LH+ L V L+ +++V + LTPL+ + S+ VE +A A++ + DK ++T + + + ++E + +++ E+ ++ ++N D + + P+H+ SN ++ L GA++ N +E +H A G V+ L++ +I+ + +++E + + LA +SGH + L + +K+ L A G + + ++ K ++ + T LH AA G +V Y ++ G + + +T +A +N H + A+ FL + WKN M + R +T ++ K ++A+ +++ +E + +S+ Y+F LD YD S + + + KY KL+ HPLS LL KW R G + L +L ++ T + H P DS +D N+ CP N+ T ++ I+ +++ E + +K Y N++ +YS+A+ + T QW + I W N++F ++ +P FGI ++MF ++V + + +F+ +I ++ +FY++ +N+ F + S K M+IGE ++ F K+F TA+ L F I+++I L+NL+VG+AV DI + A++ +Q+ + + E+ L +Q A F Y ++ ++ F ++S
Sbjct: 48 DNLRSIIHQSAREGNVNALQEALLKAPLAVNAQDGDFMTPLHYAARYGNYDAVKLLLSKNALP-NTKNREGDTPLHIASKYIYGYSDICSIIDEDQADSARKYNTATKKIINALVSENAEIDPVNKYQLTPLHYAAMKSNFSALHALIKLKADVDAEDDNKMTPLLLACVHGSQE----IIQELIKANSNVTKRDQRLNTVFHIVALRGEPEYLEMMMDHDPVEAIKALNLFNNEKKTPLRMAVEGNHPETLKKILQMEKKNSCKWMDREKELIHFAAEKGFLEVLKALVEAGGNKNELNEVKAVPLHVAAQMNQLEVVSYLIEEEKDNIDVVDEQGLTPLMMAVTHDSKKCVEYLIA-------KKANLTITDKDERTPVFIGAKFNALSSVEYILDHLRKKNKETERSALKSPTRNTLRIVSEDVRRTMVNMVDRDQNTPMHIVASNGYLEMMQLLQKHGASITQVNEDEETALHRAAIGGQTGAVRQLLEWDIRLLLMKDEMGNSALHLAARSGHDATTKVLLDNGADKEAKNSYQKTPLQVAVDSGKLETCQRLVAKGAQIE-SSSDTKTVLHTAAFYGNESIVRYFIAEGVTIDRRDEEGKTAFDIACENDHKDVARAFLETDQWKNLMIPCDVIPLDKHRNPVNMKRRTPFRTLLTKFPELASFVMDNCIEKSKEETDSTQSVA-YNFEFLDDTYMMRCVSDDGTGEQLIGCKSAYDEDFKLEKDAQSYASNYDRVYKYHPLKLMADAEKLHLLNHPLSKALLKYKWNRLGRPMYYFALFMYLVFIVSLTQYVRHTKAPYNVWNEESYYDSEYFDENETCPQINT--------TKPDVVWKIIIQTLAVCQILVECFQLFQRKFAYLVNWENWIDCFIYSTALITVYDFSECSATSGVRQNWQWILAALCIFFGWINLLFMIRKMPRFGIFVVMFVDIVKTFFRFFPVFVLFIIAFSSSFYVILQNRPEFSTIFMSPLKTTVMMIGEFEFTGIFHGDETTHAEKMFGPAHTAVACALFFFFCIIMTILLMNLLVGLAVDDIKGVQEKAELKRLAMQVDLVLQIEASLHFFIQRTKKYATCRYATFPYGKLHKTGFAGWWS 1131
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Celegans
Match: trpa-1 (Transient receptor potential cation channel subfamily A member 1 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q18297]) HSP 1 Score: 182.185 bits (461), Expect = 2.052e-46 Identity = 232/1106 (20.98%), Postives = 454/1106 (41.05%), Query Frame = 2
Query: 248 NNTFNLLHEAAISKNPELLEFILSKKP-NINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRL--NMIDIVKILLYYGANPMK-----------------SEYD-----GMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIA-------SVINSTDCEGYSCFL---------------NAIRYKQRTIILECLKYGADINLA---QNEGKNA----------LHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHA-HVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLF-----------------------QLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEM-YENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTM---------EFRFKTG---KTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLD--------------------AGPYD-----SASVNSRYTEFMTIAKYRKEKLIL---------HPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIA--------DSPDYD-NQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCT------IQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYF----LDPGFKIF----TAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQ-----AKFYEPVFVYKQMRRSVFQRFFS 3088
+N +++H++A N L+ L K P +N + T L A + GN + V+L+ + + + ++R+G TP+ +A + DI I+ A+ + +E D + LH+ ++ + L+ K + +D+N ++P+ LA G E IQ L+ + N+ +V + G +L N +++T + ++ L Q E KN+ +H A+E G+ E++ L + G N N ++ LH+ L V L+ +++V + LTPL+ + S+ VE +A A++ + DK ++T + + + ++E + +++ E+ ++ ++N D + + P+H+ SN ++ L GA++ N +E +H A G V+ L++ +I+ + +++E + + LA +SGH + L + +K+ L A G + + ++ K ++ + T LH AA G +V Y ++ G + + +T +A +N H + A+ FL + WKN M + R +T ++ K ++A+ +++ +E + +S+ Y+F LD YD S + + + KY KL+ HPLS LL KW R G + L +L ++ T + H P DS +D N+ CP N+ T ++ I+ +++ E + +K Y N++ +YS+A+ + T QW + I W N++F ++ +P FGI ++MF ++V + + +F+ +I ++ +FY++ +N+ F + S K M+IGE ++ F K+F TA+ L F I+++I L+NL+VG+AV DI + A++ +Q+ + + E+ L +Q A F Y ++ ++ F ++S
Sbjct: 47 DNLRSIIHQSAREGNVNALQEALLKAPLAVNAQDGDFMTPLHYAARYGNYDAVKLLLSKNALP-NTKNREGDTPLHIASKYIYGYSDICSIIDEDQADSARKYNTATKKIINALVSENAEIDPVNKYQLTPLHYAAMKSNFSALHALIKLKADVDAEDDNKMTPLLLACVHGSQE----IIQELIKANSNVTKRDQRLNTVFHIVALRGEPEYLEMMMDHDPVEAIKALNLFNNEKKTPLRMAVEGNHPETLKKILQMEKKNSCKWMDREKELIHFAAEKGFLEVLKALVEAGGNKNELNEVKAVPLHVAAQMNQLEVVSYLIEEEKDNIDVVDEQGLTPLMMAVTHDSKKCVEYLIA-------KKANLTITDKDERTPVFIGAKFNALSSVEYILDHLRKKNKETERSALKSPTRNTLRIVSEDVRRTMVNMVDRDQNTPMHIVASNGYLEMMQLLQKHGASITQVNEDEETALHRAAIGGQTGAVRQLLEWDIRLLLMKDEMGNSALHLAARSGHDATTKVLLDNGADKEAKNSYQKTPLQVAVDSGKLETCQRLVAKGAQIE-SSSDTKTVLHTAAFYGNESIVRYFIAEGVTIDRRDEEGKTAFDIACENDHKDVARAFLETDQWKNLMIPCDVIPLDKHRNPVNMKRRTPFRTLLTKFPELASFVMDNCIEKSKEETDSTQSVA-YNFEFLDDTYMMRCVSDDGTGEQLIGCKSAYDEDFKLEKDAQSYASNYDRVYKYHPLKLMADAEKLHLLNHPLSKALLKYKWNRLGRPMYYFALFMYLVFIVSLTQYVRHTKAPYNVWNEESYYDSEYFDENETCPQINT--------TKPDVVWKIIIQTLAVCQILVECFQLFQRKFAYLVNWENWIDCFIYSTALITVYDFSECSATSGVRQNWQWILAALCIFFGWINLLFMIRKMPRFGIFVVMFVDIVKTFFRFFPVFVLFIIAFSSSFYVILQNRPEFSTIFMSPLKTTVMMIGEFEFTGIFHGDETTHAEKMFGPAHTAVACALFFFFCIIMTILLMNLLVGLAVDDIKGVQEKAELKRLAMQVDLVLQIEASLHFFIQRTKKYATCRYATFPYGKLHKTGFAGWWS 1130
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 162.925 bits (411), Expect = 4.270e-40 Identity = 137/522 (26.25%), Postives = 239/522 (45.79%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFH-QTPLTLA 1828
LH AA S + ++++ ++ + I+ K+ G L +A + + + R + + +D TP+ +A + + K+LL A+P +G LH + N +++++LLL + + E +G++P+ +AA +G + +Q N + G + A R Q ++ ++ GA ++ E + LHIAS +G ++I+ L G N N+ + S LH+ G VA LL ++A + + TPL +L S+ G +L ++LLL V ++ K + T LH+ + H ++ L+ E + NG PLH+A N +I + L+ A+ + P+H + ++GH EI LI+ N + + + + L Q H + + LY E++SK G L AC G + MVK +++ ++ + TPLHQAAQ G V YLL GA E T QTPL++A
Sbjct: 297 LHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRA-PVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETV--------RGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPL----HLASKYG---NLEVVRLLLERGTPVDIEGKNQVTPLHV---AAHYNNDKVAMLLL---ENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE-NGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795 HSP 2 Score: 125.946 bits (315), Expect = 9.973e-29 Identity = 132/544 (24.26%), Postives = 233/544 (42.83%), Query Frame = 2
Query: 275 AAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASV---------------------INSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLID--LNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE---MYENTFHQTPLTLA 1828
AA + + E + +L +IN + G +L LA K G++E VR + K++ ++D RKG T + +A IV IL+ GAN +G L+ + NH E++K LL + + +G +P+A+A G+ + +++ K+ + ++ + T G++ A Y + L+ GA++N + LH+A++ G + + L G I+S +L + LH +G V + L+V A ++ +N L PL +A + ++L + + A V T LH+ GH+ +LL ++ NS NG PLH+AC N K+ L+ A + + P+H A G + IV L+ N T+R E + LA ++ ++ L ++ ++ L A ++G+ +V L+L+ N +PLH AA+ GQ ++ LL A+ + + F TPL LA
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQA-QVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQG-DHVDAARTLLYHR------APVDDVTVDYLTPLHVAAHCGHVRVAKLLL------DRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLH---LAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGF--TPLHLA 564 HSP 3 Score: 95.5153 bits (236), Expect = 2.093e-19 Identity = 126/536 (23.51%), Postives = 209/536 (38.99%), Query Frame = 2
Query: 773 EGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ--------------LIKEEEKQ----FLLNSYD-----DNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG---------------NNILMY------------------ACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE-DIANELLNRGLEVISDTNSVNKSL--------TKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEK----LILHPLSNMLLLNK 2170
EG + FL A R +LE L+ G DIN + G N+LH+AS+ G SE++ +L +++ ++ALH+ G + L+ N A+VNV + N TPL +A E +K LL + A+ L + T L + + GH + +L + K+++ L N ++ +G PLH+A + L+ +GAN+ + P+H AT+ G + L+ I R +D + A +SGH + + L + + +K + G L+Y A G + + KL+L + + R + TPLH A + + K+VE LL A + T TPL +A N L + R G+T + N+ D+ L+ G +V + + L T +L AG +A+ Y+ AK +E+ L+ H LL K
Sbjct: 32 EGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQ-------ENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRG-AIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVR---GETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKK 556 HSP 4 Score: 89.7373 bits (221), Expect = 1.125e-17 Identity = 115/480 (23.96%), Postives = 188/480 (39.17%), Query Frame = 2
Query: 614 LHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFL------------------KXXXXXXADVKLKD--------KKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNE---------------DEANLII------------------LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEM-YENTFHQTPLTLALDNQHWNTAKVFLND 1873
+ A +PE G + AA G LE +++ + IN+++ G + A + ++ E +K A ++ A +G ALHIAS G S I+ L +NG N+N N + L++ V + LL + A+ + + TPL + Q G ++ +A L K A + L++ K T LH+ GH +LL EK +N + PLHVA + N L+S GA + + P+H A R GH ++V DL+ + I+ + + D A ++ +A GH + + L + + +S+ G L AC+ I +V+L+LK ++ TPLH AA G +V YLL GA E +TPL LA + +V + +
Sbjct: 20 VQAPAAPEPGRAEGSASFLRAARAGDLEKVLELLRA--------GTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVAL----QQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLL------EKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVV-DLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRN 480 HSP 5 Score: 87.0409 bits (214), Expect = 7.266e-17 Identity = 74/286 (25.87%), Postives = 120/286 (41.96%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGY---------------------LEAFYLCIQS----LMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECL 1033
+ ++ LH AA E+ +L + + KG T L LA K GN E VRL+ ++G +D + + TP+ +A N + +LL GA+ + +G LH + N +E+ LL K P K G +P+ L+A G+ L A +LC Q + N + INS GY+ A + Q ++ ++ GAD+ LH A++ G + + L +NG + N + L + G +SV E L
Sbjct: 523 DNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLL-ERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 162.925 bits (411), Expect = 4.270e-40 Identity = 137/522 (26.25%), Postives = 239/522 (45.79%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFH-QTPLTLA 1828
LH AA S + ++++ ++ + I+ K+ G L +A + + + R + + +D TP+ +A + + K+LL A+P +G LH + N +++++LLL + + E +G++P+ +AA +G + +Q N + G + A R Q ++ ++ GA ++ E + LHIAS +G ++I+ L G N N+ + S LH+ G VA LL ++A + + TPL +L S+ G +L ++LLL V ++ K + T LH+ + H ++ L+ E + NG PLH+A N +I + L+ A+ + P+H + ++GH EI LI+ N + + + + L Q H + + LY E++SK G L AC G + MVK +++ ++ + TPLHQAAQ G V YLL GA E T QTPL++A
Sbjct: 297 LHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRA-PVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETV--------RGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPL----HLASKYG---NLEVVRLLLERGTPVDIEGKNQVTPLHV---AAHYNNDKVAMLLL---ENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE-NGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795 HSP 2 Score: 125.946 bits (315), Expect = 9.973e-29 Identity = 132/544 (24.26%), Postives = 233/544 (42.83%), Query Frame = 2
Query: 275 AAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASV---------------------INSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLID--LNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE---MYENTFHQTPLTLA 1828
AA + + E + +L +IN + G +L LA K G++E VR + K++ ++D RKG T + +A IV IL+ GAN +G L+ + NH E++K LL + + +G +P+A+A G+ + +++ K+ + ++ + T G++ A Y + L+ GA++N + LH+A++ G + + L G I+S +L + LH +G V + L+V A ++ +N L PL +A + ++L + + A V T LH+ GH+ +LL ++ NS NG PLH+AC N K+ L+ A + + P+H A G + IV L+ N T+R E + LA ++ ++ L ++ ++ L A ++G+ +V L+L+ N +PLH AA+ GQ ++ LL A+ + + F TPL LA
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQA-QVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQG-DHVDAARTLLYHR------APVDDVTVDYLTPLHVAAHCGHVRVAKLLL------DRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLH---LAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGF--TPLHLA 564 HSP 3 Score: 95.5153 bits (236), Expect = 2.093e-19 Identity = 126/536 (23.51%), Postives = 209/536 (38.99%), Query Frame = 2
Query: 773 EGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ--------------LIKEEEKQ----FLLNSYD-----DNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG---------------NNILMY------------------ACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE-DIANELLNRGLEVISDTNSVNKSL--------TKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEK----LILHPLSNMLLLNK 2170
EG + FL A R +LE L+ G DIN + G N+LH+AS+ G SE++ +L +++ ++ALH+ G + L+ N A+VNV + N TPL +A E +K LL + A+ L + T L + + GH + +L + K+++ L N ++ +G PLH+A + L+ +GAN+ + P+H AT+ G + L+ I R +D + A +SGH + + L + + +K + G L+Y A G + + KL+L + + R + TPLH A + + K+VE LL A + T TPL +A N L + R G+T + N+ D+ L+ G +V + + L T +L AG +A+ Y+ AK +E+ L+ H LL K
Sbjct: 32 EGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQ-------ENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRG-AIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVR---GETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKK 556 HSP 4 Score: 89.7373 bits (221), Expect = 1.125e-17 Identity = 115/480 (23.96%), Postives = 188/480 (39.17%), Query Frame = 2
Query: 614 LHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFL------------------KXXXXXXADVKLKD--------KKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNE---------------DEANLII------------------LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEM-YENTFHQTPLTLALDNQHWNTAKVFLND 1873
+ A +PE G + AA G LE +++ + IN+++ G + A + ++ E +K A ++ A +G ALHIAS G S I+ L +NG N+N N + L++ V + LL + A+ + + TPL + Q G ++ +A L K A + L++ K T LH+ GH +LL EK +N + PLHVA + N L+S GA + + P+H A R GH ++V DL+ + I+ + + D A ++ +A GH + + L + + +S+ G L AC+ I +V+L+LK ++ TPLH AA G +V YLL GA E +TPL LA + +V + +
Sbjct: 20 VQAPAAPEPGRAEGSASFLRAARAGDLEKVLELLRA--------GTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVAL----QQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLL------EKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVV-DLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRN 480 HSP 5 Score: 87.0409 bits (214), Expect = 7.266e-17 Identity = 74/286 (25.87%), Postives = 120/286 (41.96%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGY---------------------LEAFYLCIQS----LMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECL 1033
+ ++ LH AA E+ +L + + KG T L LA K GN E VRL+ ++G +D + + TP+ +A N + +LL GA+ + +G LH + N +E+ LL K P K G +P+ L+A G+ L A +LC Q + N + INS GY+ A + Q ++ ++ GAD+ LH A++ G + + L +NG + N + L + G +SV E L
Sbjct: 523 DNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLL-ERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 159.073 bits (401), Expect = 4.484e-39 Identity = 137/522 (26.25%), Postives = 239/522 (45.79%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTF-HQTPLTLA 1828
LH AA S + ++++ ++ + I+ K+ G L +A + + + R + + +D TP+ +A + + K+LL A+P +G LH + N +++++LLL + + E +G++P+ +AA +G + +Q N + G + A R Q ++ ++ GA ++ E + LHIAS +G ++I+ L G N N+ + S LH+ G VA LL ++A + + TPL +L S+ G +L ++LLL V ++ K + T LH+ + H ++ L+ E + NG PLH+A N +I + L+ A+ + P+H + ++GH EI LI+ N + + + + L Q H + + LY E++SK G L AC G + MVK +++ ++ + TPLHQAAQ G V YLL GA E T QTPL++A
Sbjct: 297 LHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRA-PVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVET--------VRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPL----HLASKYG---NLEVVRLLLERGTPVDIEGKNQVTPLHV---AAHYNNDKVAMLLL---ENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIE-NGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795 HSP 2 Score: 122.094 bits (305), Expect = 1.210e-27 Identity = 129/532 (24.25%), Postives = 227/532 (42.67%), Query Frame = 2
Query: 311 ILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASV---------------------INSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLID--LNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE---MYENTFHQTPLTLA 1828
+L +IN + G +L LA K G++E VR + K++ ++D RKG T + +A IV IL+ GAN +G L+ + NH E++K LL + + +G +P+A+A G+ + +++ K+ + ++ + T G++ A Y + L+ GA++N + LH+A++ G + + L G I+S +L + LH +G V + L+V A ++ +N L PL +A + ++L + + A V T LH+ GH+ +LL ++ NS NG PLH+AC N K+ L+ A + + P+H A G + IV L+ N T+R E + LA ++ ++ L ++ ++ L A ++G+ +V L+L+ N +PLH AA+ GQ ++ LL A+ + + F TPL LA
Sbjct: 52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQA-QVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQG-DHVDAARTLLYHR------APVDDVTVDYLTPLHVAAHCGHVRVAKLLL------DRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGE---TPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGF--TPLHLA 564 HSP 3 Score: 92.8189 bits (229), Expect = 1.013e-18 Identity = 99/408 (24.26%), Postives = 171/408 (41.91%), Query Frame = 2
Query: 770 CEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ--------------LIKEEEKQ----FLLNSYDDN-----GDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKT 1921
EG + FL A R +LE L+ G DIN + G N+LH+AS+ G SE++ +L +++ ++ALH+ G + L+ N A+VNV + N TPL +A E +K LL + A+ L + T L + + GH + +L + K+++ L N ++ + G PLH+A + L+ +GAN+ + P+H AT+ G + L+ I R +D + A +SGH + + L + + +K + G L A Q + + +L + TPLH AA G ++ + LL A+ + TPL +A ++ L ++ +E ++G T
Sbjct: 31 AEGSASFLRAARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQ-------ENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGA-IIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLL---KYRAAIEATTESGLT 427 HSP 4 Score: 88.5817 bits (218), Expect = 2.251e-17 Identity = 125/516 (24.22%), Postives = 200/516 (38.76%), Query Frame = 2
Query: 614 LHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFL------------------KXXXXXXADVKLKD--------KKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNE---------------DEANLII------------------LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEM-YENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRG 1981
+ A +PE G + AA G LE +++ + IN+++ G + A + ++ E +K A ++ A +G ALHIAS G S I+ L +NG N+N N + L++ V + LL + A+ + + TPL + Q G ++ +A L K A + L++ K T LH+ GH +LL EK +N + PLHVA + N L+S GA + + P+H A R GH ++V DL+ + I+ + + D A ++ +A GH + + L + + +S+ G L AC+ I +V+L+LK ++ TPLH AA G +V YLL GA E +TPL LA + +V + N K + R H+ + N DI LL G
Sbjct: 20 VQAPAAPEPGRAEGSASFLRAARAGDLEKVLELLRA--------GTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLA----VALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLL------EKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVV-DLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIR-NGAKVDAQARELQTPLHIAS-RLGNTDIVILLLQAG 514 HSP 5 Score: 84.7297 bits (208), Expect = 2.832e-16 Identity = 75/286 (26.22%), Postives = 123/286 (43.01%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLE---------------------AFYLCIQS--LMNSKI--NIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECL 1033
+ ++ LH AA E+ +L + + KG T L LA K GN E VRL+ ++G +D + + TP+ +A N + +LL GA+ + +G LH + N +E+ LL K P K G +P+ L+A G+ E A +LC Q + ++I N + INS GY+ A + Q ++ ++ GAD+ LH A++ G + + L +NG + N + L + G +SV E L
Sbjct: 523 DNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLL-ERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Fly
Match: TrpA1 (gene:FBgn0035934 transcript:FBtr0331823) HSP 1 Score: 197.208 bits (500), Expect = 5.849e-51 Identity = 221/984 (22.46%), Postives = 406/984 (41.26%), Query Frame = 2
Query: 269 HEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQ--DRKGQTPIDLACRLNMIDIVKILLYYG--ANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL-----CDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIET--IELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAV--QSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKN-TMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAK------------YRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMN------------------------------SIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDP---MCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIV-------NRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXM---VGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
H+AA +L +I + + N K G+T L +AV+S + + + + +D + K Q P+ LA LN + ++++ Y + + G LH +H E ++L+ P NNG PI AA + + Q +I+ D EG +A+ + CLK GA I+ Q++ +H+A G +I+ + + + ++ D + LH + L+ A +N ++ +PLL +A S+ G + ++L A + +KD + +LH +I +G T E + + + + LLN D G PLH A + + LI GA + L N N P+H A R G V+ L+D I D A + L + Q GH + + L + +H +D TG N L A G ++L+ +L + +T LH A + + L+S+G ++ N + + A+ ++ A + N M R +I + + ++ + + KY F L P+ A ++ + E +T A + + +L+ HPLS L KW +G +F + +L+ + +L F T M I DN T ++ ++ ++TMN ++ ++ L + E ++ QKL Y N + ++Y SA+ P + TI +S +IA+ L W ++ +LQ GI ++MF ++ ++IK++++F L+I + +AFYI+ N F N S + + M++GELD+V +++ ++ + + + S+ + + I LM +G+AVGDI+ + +A++ +Q+ +E E LP
Sbjct: 130 HQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLL---SIPVDTGVLNEKKQAPVHLATELNKVKSLRVMGQYRNVIDIQQGGEHGRTALHLAAIYDHEECARILITEFDACPRKPCNNGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAA---SRSGWKTVHLLIRLG----ACISVKDAAARNVLHFVIMNGGRLTDFAEQVANCQTQAQLKLLLNEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRGALLH-RDHTGRNPLQLAAMSGYTETIELLHSVHSHLLDQVDKDGNTALHLATMENKPHAISVLMSMGCKLVYNVLDMSAIDYAIYYKYPEAALAMVTHEERANEVMALRSDKHPCVTLALIASMPKVFEAVQDKCITKANCKKDSKSFYIKYSFAFLQC-PFMFAKIDEKTGESITTASPIPLPALNTMVTHGRVELLAHPLSQKYLQMKWNSYGKYFHLANLLIYSIFLVFVTIYSSLMMNNIELKAG--------DNKTMSQYCNMGWEQLTMNLSQNPSVASQIRLDSCEERINRTTAILFCAVVIVVYILLNSMRELIQIYQQKLHYILETVNLISWVLYISALVMVTPAFQPDGGINTIHYSAASIAVFLSWFRLLLFLQRFDQVGIYVVMFLEILQTLIKVLMVFSILIIAFGLAFYILLSKIIDPQPNHLSFSNIPMSLLRTFSMMLGELDFVGTYVNTYYRDQLKVPMTSFLILSVFMILMPILLMNLLIGLAVGDIESVRRNAQLKRLAMQVVLHTELERKLP 1093
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Fly
Match: TrpA1 (gene:FBgn0035934 transcript:FBtr0331825) HSP 1 Score: 196.823 bits (499), Expect = 6.284e-51 Identity = 221/984 (22.46%), Postives = 406/984 (41.26%), Query Frame = 2
Query: 269 HEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQ--DRKGQTPIDLACRLNMIDIVKILLYYG--ANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL-----CDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIET--IELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAV--QSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKN-TMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAK------------YRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMN------------------------------SIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDP---MCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIV-------NRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXM---VGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
H+AA +L +I + + N K G+T L +AV+S + + + + +D + K Q P+ LA LN + ++++ Y + + G LH +H E ++L+ P NNG PI AA + + Q +I+ D EG +A+ + CLK GA I+ Q++ +H+A G +I+ + + + ++ D + LH + L+ A +N ++ +PLL +A S+ G + ++L A + +KD + +LH +I +G T E + + + + LLN D G PLH A + + LI GA + L N N P+H A R G V+ L+D I D A + L + Q GH + + L + +H +D TG N L A G ++L+ +L + +T LH A + + L+S+G ++ N + + A+ ++ A + N M R +I + + ++ + + KY F L P+ A ++ + E +T A + + +L+ HPLS L KW +G +F + +L+ + +L F T M I DN T ++ ++ ++TMN ++ ++ L + E ++ QKL Y N + ++Y SA+ P + TI +S +IA+ L W ++ +LQ GI ++MF ++ ++IK++++F L+I + +AFYI+ N F N S + + M++GELD+V +++ ++ + + + S+ + + I LM +G+AVGDI+ + +A++ +Q+ +E E LP
Sbjct: 95 HQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLL---SIPVDTGVLNEKKQAPVHLATELNKVKSLRVMGQYRNVIDIQQGGEHGRTALHLAAIYDHEECARILITEFDACPRKPCNNGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAA---SRSGWKTVHLLIRLG----ACISVKDAAARNVLHFVIMNGGRLTDFAEQVANCQTQAQLKLLLNEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRGALLH-RDHTGRNPLQLAAMSGYTETIELLHSVHSHLLDQVDKDGNTALHLATMENKPHAISVLMSMGCKLVYNVLDMSAIDYAIYYKYPEAALAMVTHEERANEVMALRSDKHPCVTLALIASMPKVFEAVQDKCITKANCKKDSKSFYIKYSFAFLQC-PFMFAKIDEKTGESITTASPIPLPALNTMVTHGRVELLAHPLSQKYLQMKWNSYGKYFHLANLLIYSIFLVFVTIYSSLMMNNIELKAG--------DNKTMSQYCNMGWEQLTMNLSQNPSVASQIRLDSCEERINRTTAILFCAVVIVVYILLNSMRELIQIYQQKLHYILETVNLISWVLYISALVMVTPAFQPDGGINTIHYSAASIAVFLSWFRLLLFLQRFDQVGIYVVMFLEILQTLIKVLMVFSILIIAFGLAFYILLSKIIDPQPNHLSFSNIPMSLLRTFSMMLGELDFVGTYVNTYYRDQLKVPMTSFLILSVFMILMPILLMNLLIGLAVGDIESVRRNAQLKRLAMQVVLHTELERKLP 1058
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Fly
Match: TrpA1 (gene:FBgn0035934 transcript:FBtr0331824) HSP 1 Score: 194.126 bits (492), Expect = 5.315e-50 Identity = 219/985 (22.23%), Postives = 404/985 (41.02%), Query Frame = 2
Query: 269 HEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQ--DRKGQTPIDLACRLNMIDIVKILLYYG--ANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIP-----KLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIET--IELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAV--QSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFN-LQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKN-TMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEF-------------MTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMN------------------------------SIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDP---MCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIV-------NRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXM---VGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
H+AA +L +I + + N K G+T L +AV+S + + + + +D + K Q P+ LA LN + ++++ Y + + G LH +H E ++L+ P NNG PI AA + + Q +I+ D EG +A+ + CLK GA I+ Q++ +H+A G +I+ + + + ++ D + LH + L+ A +N ++ +PLL +A S+ G + ++L A + +KD + +LH +I +G T E + + + + LLN D G PLH A + + LI GA + L N N P+H A R G V+ L+D I D A + L + Q GH + + L + +H +D TG N L A G ++L+ + L + +T LH A + + L+S+G ++ N + + A+ ++ A + N M R +I + + ++ + + KY F+ P + ++ EF T+ + + +L+ HPLS L KW +G +F + +L+ + +L F T M I DN T ++ ++ ++TMN ++ ++ L + E ++ QKL Y N + ++Y SA+ P + TI +S +IA+ L W ++ +LQ GI ++MF ++ ++IK++++F L+I + +AFYI+ N F N S + + M++GELD+V +++ ++ + + + S+ + + I LM +G+AVGDI+ + +A++ +Q+ +E E LP
Sbjct: 130 HQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLL---SIPVDTGVLNEKKQAPVHLATELNKVKSLRVMGQYRNVIDIQQGGEHGRTALHLAAIYDHEECARILITEFDACPRKPCNNGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAA---SRSGWKTVHLLIRLG----ACISVKDAAARNVLHFVIMNGGRLTDFAEQVANCQTQAQLKLLLNEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRGALLH-RDHTGRNPLQLAAMSGYTETIELLHSVHSHLLDQVDKDGNTALHLATMENKPHAISVLMSMGCKLVYNVLDMSAIDYAIYYKYPEAALAMVTHEERANEVMALRSDKHPCVTLALIASMPKVFEAVQDKCITKANCKKDSKSFYIKYSFWPYQKTP---EQIEAKRKEFNDPKWRPAPLAVVNTMVTHGRVELLAHPLSQKYLQMKWNSYGKYFHLANLLIYSIFLVFVTIYSSLMMNNIELKAG--------DNKTMSQYCNMGWEQLTMNLSQNPSVASQIRLDSCEERINRTTAILFCAVVIVVYILLNSMRELIQIYQQKLHYILETVNLISWVLYISALVMVTPAFQPDGGINTIHYSAASIAVFLSWFRLLLFLQRFDQVGIYVVMFLEILQTLIKVLMVFSILIIAFGLAFYILLSKIIDPQPNHLSFSNIPMSLLRTFSMMLGELDFVGTYVNTYYRDQLKVPMTSFLILSVFMILMPILLMNLLIGLAVGDIESVRRNAQLKRLAMQVVLHTELERKLP 1092 HSP 2 Score: 65.4698 bits (158), Expect = 2.841e-10 Identity = 89/391 (22.76%), Postives = 150/391 (38.36%), Query Frame = 2
Query: 854 INLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNE------DEANLII-LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLI-----LKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYE-NTFHQTPLTLALDNQHWNT--------AKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIAN 1963
I L +G+ A H A+ I+ + D + N+ DN ++ LH+ + + + + LL V N P+ +L +++ KSL + N D++ + +T LHL H EE + L+ +D AC RK CN N PIHEA + + ++ Q+ R E E N+ + AV G E ++ ++ + + AC G I +VKL+ ++K L + + TPLH A+ +V YL++ GA++ + H++PL LA W T A + + D +N + F G G + E +AN
Sbjct: 118 IALKDAKGRTAAHQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLLSIPVDTGVLNEKKQAPV----HLATELNKVKSLRVMGQYRNVI-DIQQGGEHGRTALHLAAIYDH------------EECARILITEFD---------ACP---RKPCN--------------NGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAASRSGWKTVHLLIRLGACISVKDAAARNVLHFVIMNG----GRLTDFAEQVAN 461
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Fly
Match: TrpA1 (gene:FBgn0035934 transcript:FBtr0331826) HSP 1 Score: 193.741 bits (491), Expect = 5.477e-50 Identity = 219/985 (22.23%), Postives = 404/985 (41.02%), Query Frame = 2
Query: 269 HEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQ--DRKGQTPIDLACRLNMIDIVKILLYYG--ANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL-----CDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIET--IELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAV--QSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFN-LQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKN-TMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEF-------------MTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMN------------------------------SIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDP---MCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIV-------NRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXM---VGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
H+AA +L +I + + N K G+T L +AV+S + + + + +D + K Q P+ LA LN + ++++ Y + + G LH +H E ++L+ P NNG PI AA + + Q +I+ D EG +A+ + CLK GA I+ Q++ +H+A G +I+ + + + ++ D + LH + L+ A +N ++ +PLL +A S+ G + ++L A + +KD + +LH +I +G T E + + + + LLN D G PLH A + + LI GA + L N N P+H A R G V+ L+D I D A + L + Q GH + + L + +H +D TG N L A G ++L+ + L + +T LH A + + L+S+G ++ N + + A+ ++ A + N M R +I + + ++ + + KY F+ P + ++ EF T+ + + +L+ HPLS L KW +G +F + +L+ + +L F T M I DN T ++ ++ ++TMN ++ ++ L + E ++ QKL Y N + ++Y SA+ P + TI +S +IA+ L W ++ +LQ GI ++MF ++ ++IK++++F L+I + +AFYI+ N F N S + + M++GELD+V +++ ++ + + + S+ + + I LM +G+AVGDI+ + +A++ +Q+ +E E LP
Sbjct: 95 HQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLL---SIPVDTGVLNEKKQAPVHLATELNKVKSLRVMGQYRNVIDIQQGGEHGRTALHLAAIYDHEECARILITEFDACPRKPCNNGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAA---SRSGWKTVHLLIRLG----ACISVKDAAARNVLHFVIMNGGRLTDFAEQVANCQTQAQLKLLLNEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRGALLH-RDHTGRNPLQLAAMSGYTETIELLHSVHSHLLDQVDKDGNTALHLATMENKPHAISVLMSMGCKLVYNVLDMSAIDYAIYYKYPEAALAMVTHEERANEVMALRSDKHPCVTLALIASMPKVFEAVQDKCITKANCKKDSKSFYIKYSFWPYQKTP---EQIEAKRKEFNDPKWRPAPLAVVNTMVTHGRVELLAHPLSQKYLQMKWNSYGKYFHLANLLIYSIFLVFVTIYSSLMMNNIELKAG--------DNKTMSQYCNMGWEQLTMNLSQNPSVASQIRLDSCEERINRTTAILFCAVVIVVYILLNSMRELIQIYQQKLHYILETVNLISWVLYISALVMVTPAFQPDGGINTIHYSAASIAVFLSWFRLLLFLQRFDQVGIYVVMFLEILQTLIKVLMVFSILIIAFGLAFYILLSKIIDPQPNHLSFSNIPMSLLRTFSMMLGELDFVGTYVNTYYRDQLKVPMTSFLILSVFMILMPILLMNLLIGLAVGDIESVRRNAQLKRLAMQVVLHTELERKLP 1057 HSP 2 Score: 65.0846 bits (157), Expect = 3.956e-10 Identity = 89/391 (22.76%), Postives = 150/391 (38.36%), Query Frame = 2
Query: 854 INLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNE------DEANLII-LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLI-----LKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYE-NTFHQTPLTLALDNQHWNT--------AKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIAN 1963
I L +G+ A H A+ I+ + D + N+ DN ++ LH+ + + + + LL V N P+ +L +++ KSL + N D++ + +T LHL H EE + L+ +D AC RK CN N PIHEA + + ++ Q+ R E E N+ + AV G E ++ ++ + + AC G I +VKL+ ++K L + + TPLH A+ +V YL++ GA++ + H++PL LA W T A + + D +N + F G G + E +AN
Sbjct: 83 IALKDAKGRTAAHQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLLSIPVDTGVLNEKKQAPV----HLATELNKVKSLRVMGQYRNVI-DIQQGGEHGRTALHLAAIYDH------------EECARILITEFD---------ACP---RKPCN--------------NGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAASRSGWKTVHLLIRLGACISVKDAAARNVLHFVIMNG----GRLTDFAEQVAN 426
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Fly
Match: TrpA1 (gene:FBgn0035934 transcript:FBtr0331827) HSP 1 Score: 193.741 bits (491), Expect = 5.966e-50 Identity = 220/972 (22.63%), Postives = 400/972 (41.15%), Query Frame = 2
Query: 269 HEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQ--DRKGQTPIDLACRLNMIDIVKILLYYG--ANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL-----CDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIET--IELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAV--QSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFN-LQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKN-TMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMN------------------------------SIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDP---MCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIV-------NRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXM---VGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
H+AA +L +I + + N K G+T L +AV+S + + + + +D + K Q P+ LA LN + ++++ Y + + G LH +H E ++L+ P NNG PI AA + + Q +I+ D EG +A+ + CLK GA I+ Q++ +H+A G +I+ + + + ++ D + LH + L+ A +N ++ +PLL +A S+ G + ++L A + +KD + +LH +I +G T E + + + + LLN D G PLH A + + LI GA + L N N P+H A R G V+ L+D I D A + L + Q GH + + L + +H +D TG N L A G ++L+ + L + +T LH A + + L+S+G ++ N + + A+ ++ A + N M R +I + + E + D K +TK A+ F T+ + + +L+ HPLS L KW +G +F + +L+ + +L F T M I DN T ++ ++ ++TMN ++ ++ L + E ++ QKL Y N + ++Y SA+ P + TI +S +IA+ L W ++ +LQ GI ++MF ++ ++IK++++F L+I + +AFYI+ N F N S + + M++GELD+V +++ ++ + + + S+ + + I LM +G+AVGDI+ + +A++ +Q+ +E E LP
Sbjct: 130 HQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLL---SIPVDTGVLNEKKQAPVHLATELNKVKSLRVMGQYRNVIDIQQGGEHGRTALHLAAIYDHEECARILITEFDACPRKPCNNGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAA---SRSGWKTVHLLIRLG----ACISVKDAAARNVLHFVIMNGGRLTDFAEQVANCQTQAQLKLLLNEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRGALLH-RDHTGRNPLQLAAMSGYTETIELLHSVHSHLLDQVDKDGNTALHLATMENKPHAISVLMSMGCKLVYNVLDMSAIDYAIYYKYPEAALAMVTHEERANEVMALRSDKHPCVTLALIAS--------MPKVFEAVQD-----KCITK-------------ANCKKDSKSFYTMVTHGRVELLAHPLSQKYLQMKWNSYGKYFHLANLLIYSIFLVFVTIYSSLMMNNIELKAG--------DNKTMSQYCNMGWEQLTMNLSQNPSVASQIRLDSCEERINRTTAILFCAVVIVVYILLNSMRELIQIYQQKLHYILETVNLISWVLYISALVMVTPAFQPDGGINTIHYSAASIAVFLSWFRLLLFLQRFDQVGIYVVMFLEILQTLIKVLMVFSILIIAFGLAFYILLSKIIDPQPNHLSFSNIPMSLLRTFSMMLGELDFVGTYVNTYYRDQLKVPMTSFLILSVFMILMPILLMNLLIGLAVGDIESVRRNAQLKRLAMQVVLHTELERKLP 1056 HSP 2 Score: 65.0846 bits (157), Expect = 3.727e-10 Identity = 89/391 (22.76%), Postives = 150/391 (38.36%), Query Frame = 2
Query: 854 INLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNE------DEANLII-LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLI-----LKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYE-NTFHQTPLTLALDNQHWNT--------AKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIAN 1963
I L +G+ A H A+ I+ + D + N+ DN ++ LH+ + + + + LL V N P+ +L +++ KSL + N D++ + +T LHL H EE + L+ +D AC RK CN N PIHEA + + ++ Q+ R E E N+ + AV G E ++ ++ + + AC G I +VKL+ ++K L + + TPLH A+ +V YL++ GA++ + H++PL LA W T A + + D +N + F G G + E +AN
Sbjct: 118 IALKDAKGRTAAHQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLLSIPVDTGVLNEKKQAPV----HLATELNKVKSLRVMGQYRNVI-DIQQGGEHGRTALHLAAIYDH------------EECARILITEFD---------ACP---RKPCN--------------NGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAASRSGWKTVHLLIRLGACISVKDAAARNVLHFVIMNG----GRLTDFAEQVAN 461
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Zebrafish
Match: trpa1b (transient receptor potential cation channel, subfamily A, member 1b [Source:ZFIN;Acc:ZDB-GENE-050106-1]) HSP 1 Score: 199.134 bits (505), Expect = 1.152e-51 Identity = 253/1008 (25.10%), Postives = 428/1008 (42.46%), Query Frame = 2
Query: 230 IDENHPNNTFNLLHEAAISKNPELLEFILSKKP-NINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEI-DGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAASLGYLEAFY--------LCIQ-----------SLMNSKINIASVINSTDCEGYSCFLN--------------AIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSL----SVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI--ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLG--NYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTM-EFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDA-------GPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQG------CPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMC-----TIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFL---DPGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYEPVFV 3046
I+E+ + ++ E A ++ ++ K P +++ + G++ L A GN + +RLI G E+ + QD +G+TP+ A + +LL GA+P M LH + + + ++LL K + ++ + G +P+ LA S +A +CIQ + +K + V+ + G S L+ A+R +I C+ GA + Q+ ALH A G E + + + + N D A +H +L +AE L+ A ++ + L+PLL L S K++A+L L+ AD K+K+K + LH +I G E + Q +E +L+ D G PLH AC + ++ G N+ LG + + +H A G + L++ + + DE L + LA ++GH + + L K S D G L +A G +K++L + L +N +T LH AAQAG V LL GAE+ N + L A+ N+ + +M F+ K+ + I E + L E D NS + + Y+F L A D + +Y + +L++HPLS L KW +GS +L +L L T++I + P S D+ PV S L S+ I M +M+++ + E ++ Q++ YF SN SA+ F PMC T QW G AI+ W + Y Q GI ++MF +V +++ I++LF+ L++ + +AFY + ++ F + + A+ + M +GEL+Y S FL + G F A+ ++ F +L+ I L+NLM+G+AVGDI + +A++ +QI + E LP + +P V
Sbjct: 18 INEDETEESADVF-ELAFKGKASAIDRLIQKGPEHLSLRDENGASLLHYASAGGNLDIIRLIVSIVGPEVLNVQDEQGRTPLHWAVEQDQQQSCAVLLDLGADPNILNNALMGPLHLAVTKQYNHLAEVLLSCDKTNSNLEGDLGNTPVMLACSNNNCQALQILIKRGAKMCIQNKLGHYPIHTVAFAGAKEAMEMVLKIGEELGVSSTLHINYLDKSKSTPLHLAVRGGNIEVIKLCILKGAKVEQHQSGKCTALHFACSQGSLEAVKIMLSSYNRTEDIVNIRDGANRTPLHRATLFDHVELAEYLISKGAEIDSIDCKGLSPLL----LASSCSAWKTVAYL---LSIGADFKIKEKTGRNFLHFVILQPKGLKNLPETVLQSTAVKE---MLSDEDVEGCTPLHYACKLGIHDSVKNML--GLNICLGQKSREKKSALHFAAEYGRINTCHRLLETLTDSKMLNDWDEKGLTPLHLASRAGHAQVVDLLLRKGALFQS-DYKGWTCLHHAAAEGYTQTMKILLAANVKLLDEKNEDGNTALHIAAQAGHVSAVLLLLDRGAEIALNDADNSFLHEAVRNERREVVNATIEHERCDESMTSFKAKSRCVVLDIIEFLPESFQHLLDQCITESDHDANSQDYHIM-YNFQWLQAPIQLKKYAKTDKTKAFQPLAALNAMVRYNRLELLIHPLSRKYLEMKWTAYGSKVHFLNLAIYLLGLLPLTYLILNLRP----SQDFSKGNGTSVIMVPVSFSEQQYLISVC---IIMVIVMNVYSICK---EVVQLAQQRVNYFTDFSNPADWSAAISALVFVV----PMCCSVEATWQWEAGAYAILTSWIGFLLYFQRFERIGIYVVMFNGIVRTLVCIMVLFVFLLLAFGLAFYALMLHRPEFSSISLALAQTFVMTVGELNYQSTFLNSYEEGHMAFPAITYLVFVFFVLLMPILLMNLMIGLAVGDIAEVQRNAELKRIAMQIDLHTALEEKLPYWFLKRVDKPSTV 996
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Zebrafish
Match: trpa1b (transient receptor potential cation channel, subfamily A, member 1b [Source:ZFIN;Acc:ZDB-GENE-050106-1]) HSP 1 Score: 199.134 bits (505), Expect = 1.152e-51 Identity = 253/1008 (25.10%), Postives = 428/1008 (42.46%), Query Frame = 2
Query: 230 IDENHPNNTFNLLHEAAISKNPELLEFILSKKP-NINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEI-DGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAASLGYLEAFY--------LCIQ-----------SLMNSKINIASVINSTDCEGYSCFLN--------------AIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSL----SVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI--ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLG--NYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTM-EFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDA-------GPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQG------CPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMC-----TIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFL---DPGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYEPVFV 3046
I+E+ + ++ E A ++ ++ K P +++ + G++ L A GN + +RLI G E+ + QD +G+TP+ A + +LL GA+P M LH + + + ++LL K + ++ + G +P+ LA S +A +CIQ + +K + V+ + G S L+ A+R +I C+ GA + Q+ ALH A G E + + + + N D A +H +L +AE L+ A ++ + L+PLL L S K++A+L L+ AD K+K+K + LH +I G E + Q +E +L+ D G PLH AC + ++ G N+ LG + + +H A G + L++ + + DE L + LA ++GH + + L K S D G L +A G +K++L + L +N +T LH AAQAG V LL GAE+ N + L A+ N+ + +M F+ K+ + I E + L E D NS + + Y+F L A D + +Y + +L++HPLS L KW +GS +L +L L T++I + P S D+ PV S L S+ I M +M+++ + E ++ Q++ YF SN SA+ F PMC T QW G AI+ W + Y Q GI ++MF +V +++ I++LF+ L++ + +AFY + ++ F + + A+ + M +GEL+Y S FL + G F A+ ++ F +L+ I L+NLM+G+AVGDI + +A++ +QI + E LP + +P V
Sbjct: 18 INEDETEESADVF-ELAFKGKASAIDRLIQKGPEHLSLRDENGASLLHYASAGGNLDIIRLIVSIVGPEVLNVQDEQGRTPLHWAVEQDQQQSCAVLLDLGADPNILNNALMGPLHLAVTKQYNHLAEVLLSCDKTNSNLEGDLGNTPVMLACSNNNCQALQILIKRGAKMCIQNKLGHYPIHTVAFAGAKEAMEMVLKIGEELGVSSTLHINYLDKSKSTPLHLAVRGGNIEVIKLCILKGAKVEQHQSGKCTALHFACSQGSLEAVKIMLSSYNRTEDIVNIRDGANRTPLHRATLFDHVELAEYLISKGAEIDSIDCKGLSPLL----LASSCSAWKTVAYL---LSIGADFKIKEKTGRNFLHFVILQPKGLKNLPETVLQSTAVKE---MLSDEDVEGCTPLHYACKLGIHDSVKNML--GLNICLGQKSREKKSALHFAAEYGRINTCHRLLETLTDSKMLNDWDEKGLTPLHLASRAGHAQVVDLLLRKGALFQS-DYKGWTCLHHAAAEGYTQTMKILLAANVKLLDEKNEDGNTALHIAAQAGHVSAVLLLLDRGAEIALNDADNSFLHEAVRNERREVVNATIEHERCDESMTSFKAKSRCVVLDIIEFLPESFQHLLDQCITESDHDANSQDYHIM-YNFQWLQAPIQLKKYAKTDKTKAFQPLAALNAMVRYNRLELLIHPLSRKYLEMKWTAYGSKVHFLNLAIYLLGLLPLTYLILNLRP----SQDFSKGNGTSVIMVPVSFSEQQYLISVC---IIMVIVMNVYSICK---EVVQLAQQRVNYFTDFSNPADWSAAISALVFVV----PMCCSVEATWQWEAGAYAILTSWIGFLLYFQRFERIGIYVVMFNGIVRTLVCIMVLFVFLLLAFGLAFYALMLHRPEFSSISLALAQTFVMTVGELNYQSTFLNSYEEGHMAFPAITYLVFVFFVLLMPILLMNLMIGLAVGDIAEVQRNAELKRIAMQIDLHTALEEKLPYWFLKRVDKPSTV 996
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Zebrafish
Match: trpa1b (transient receptor potential cation channel, subfamily A, member 1b [Source:ZFIN;Acc:ZDB-GENE-050106-1]) HSP 1 Score: 190.274 bits (482), Expect = 9.068e-49 Identity = 254/1021 (24.88%), Postives = 428/1021 (41.92%), Query Frame = 2
Query: 230 IDENHPNNTFNLLHEAAISKNPELLEFILSKKP-NINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEI-DGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAASLGYLEAFY--------LCIQ-----------SLMNSKINIASVINSTDCEGYSCFLN--------------AIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSL----SVAECL-------------LVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI--ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLG--NYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTM-EFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDA-------GPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQG------CPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMC-----TIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFL---DPGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYEPVFV 3046
I+E+ + ++ E A ++ ++ K P +++ + G++ L A GN + +RLI G E+ + QD +G+TP+ A + +LL GA+P M LH + + + ++LL K + ++ + G +P+ LA S +A +CIQ + +K + V+ + G S L+ A+R +I C+ GA + Q+ ALH A G E + + + + N D A +H +L +AE L L A ++ + L+PLL L S K++A+L L+ AD K+K+K + LH +I G E + Q +E +L+ D G PLH AC + ++ G N+ LG + + +H A G + L++ + + DE L + LA ++GH + + L K S D G L +A G +K++L + L +N +T LH AAQAG V LL GAE+ N + L A+ N+ + +M F+ K+ + I E + L E D NS + + Y+F L A D + +Y + +L++HPLS L KW +GS +L +L L T++I + P S D+ PV S L S+ I M +M+++ + E ++ Q++ YF SN SA+ F PMC T QW G AI+ W + Y Q GI ++MF +V +++ I++LF+ L++ + +AFY + ++ F + + A+ + M +GEL+Y S FL + G F A+ ++ F +L+ I L+NLM+G+AVGDI + +A++ +QI + E LP + +P V
Sbjct: 18 INEDETEESADVF-ELAFKGKASAIDRLIQKGPEHLSLRDENGASLLHYASAGGNLDIIRLIVSIVGPEVLNVQDEQGRTPLHWAVEQDQQQSCAVLLDLGADPNILNNALMGPLHLAVTKQYNHLAEVLLSCDKTNSNLEGDLGNTPVMLACSNNNCQALQILIKRGAKMCIQNKLGHYPIHTVAFAGAKEAMEMVLKIGEELGVSSTLHINYLDKSKSTPLHLAVRGGNIEVIKLCILKGAKVEQHQSGKCTALHFACSQGSLEAVKIMLSSYNRTEDIVNIRDGANRTPLHRATLFDHVELAEYLISKPNTLSLDLICLGKGAEIDSIDCKGLSPLL----LASSCSAWKTVAYL---LSIGADFKIKEKTGRNFLHFVILQPKGLKNLPETVLQSTAVKE---MLSDEDVEGCTPLHYACKLGIHDSVKNML--GLNICLGQKSREKKSALHFAAEYGRINTCHRLLETLTDSKMLNDWDEKGLTPLHLASRAGHAQVVDLLLRKGALFQS-DYKGWTCLHHAAAEGYTQTMKILLAANVKLLDEKNEDGNTALHIAAQAGHVSAVLLLLDRGAEIALNDADNSFLHEAVRNERREVVNATIEHERCDESMTSFKAKSRCVVLDIIEFLPESFQHLLDQCITESDHDANSQDYHIM-YNFQWLQAPIQLKKYAKTDKTKAFQPLAALNAMVRYNRLELLIHPLSRKYLEMKWTAYGSKVHFLNLAIYLLGLLPLTYLILNLRP----SQDFSKGNGTSVIMVPVSFSEQQYLISVC---IIMVIVMNVYSICK---EVVQLAQQRVNYFTDFSNPADWSAAISALVFVV----PMCCSVEATWQWEAGAYAILTSWIGFLLYFQRFERIGIYVVMFNGIVRTLVCIMVLFVFLLLAFGLAFYALMLHRPEFSSISLALAQTFVMTVGELNYQSTFLNSYEEGHMAFPAITYLVFVFFVLLMPILLMNLMIGLAVGDIAEVQRNAELKRIAMQIDLHTALEEKLPYWFLKRVDKPSTV 1009
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Zebrafish
Match: trpa1a (transient receptor potential cation channel, subfamily A, member 1a [Source:ZFIN;Acc:ZDB-GENE-050105-6]) HSP 1 Score: 181.03 bits (458), Expect = 6.814e-46 Identity = 235/975 (24.10%), Postives = 411/975 (42.15%), Query Frame = 2
Query: 275 AAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKG-MEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIR-SNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYL--------CIQSLMN-------------------------SKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEII-------PKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTH----MGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLD-------AGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFF--TFMIFHYMPPIADSPDYD--NQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKV-KDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDP---GFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
AA+ KN L+ + NI G++ L A +G+ +R I + G E++ +D +G TP+ A + + +LL GA+P +H + + + +L+ H + ++ + G +P+ L+A+L EA + C Q+ + + ++I + IN D S A+R II C+ YGA I+ Q + ALH A G +E++ PK+CD IN D + LH + ++E L+ A+++ + +PLL L + G +++ L L++ AD+ KDK LHL I L ++++ E + LLN D G PLH AC + ++ +L + + +H A G + L+++ + DE L + LA + GH + E L K HS D G + L +A G + +L + L + +T LH AA+AG V LL GA++ N + L A+ N + + + + M +K T M I E + L E D N N + +Y+F L + + + + + L+ HP+ L KW +G + ++ + LG F T++I + P + S + N C ++ K LT S + + M+M+ + E L+ Q+L Y + SNY+ A+ F + + + W G +A + W N++ YLQ GI ++MF+ + +++ II+LF L++G+A++FY + Q F + S + + M++GE++Y F+ P G F + L + F +L+ I L+NL++G+AVGDI + +A + +QI + E LP
Sbjct: 56 AALEKNSRYLD----TRDNI------GASPLHYASANGHFRIIRHIVQIVGHQELNVRDEEGNTPLHWAVQKDQPGSCSVLLSLGADPNVLNNSHQAPIHMAVSLGKNFVLEQLVSHKQTDVNLEGDLGNTPVILSAALDNHEALGILYKHGAKFCRQNNLGHFPIHAAAFSGAKKSMEVILLKGEEAGLSIDAHINYVDKSCSSPLHLAVRGGNLDIIKLCIGYGAKIDQQQCDKSTALHFACSQGATEVVKIMLSSYPKVCDL---INITDGANQTPLHKAVIFDHFELSEYLMSQGANIDFVDCKGHSPLL----LATSCGAWRTVNLL---LSHGADLTKKDKSGCNFLHLAILQPR-GLKNLPTEVLQHESVRELLNDEDIEGCTPLHYACRLGIPDSVKNMLGLEVSLDQKSKEKKSALHFAAEFGRINTCHRLLEMVTDTRLLNEGDEKGLTPLHLASREGHVKVVELLLRKGALFHS-DYRGWSGLHHAASEGYTQTMDTLLTSNIKLLNKTDGDGNTALHLAARAGHVAAVRLLLYRGAKIILNKNDASFLHEAVHNARREVTNMVIESDRCEEAMT-TYKPNSTKRCIVMDMIEFLPESFKHLLDTCIRESEEDVNCTNYYI-EYNFRWLQHPLQNLKKTGMEKDMAYKPLSALNAMVNFNRVNLLTHPVCKKYLEMKWSAYGIKAHLLNMTVYA--LGVFPLTYLIVNLKPTLVTSRNVTSVNMVC----TSLYKQSYLTTSSMLLVLAMNMYAVGK---EILQMFQQRLNYLRDLSNYMDWAAAICALLFVVPLLMNLKSSWHWQAGALAALTSWLNLLLYLQRFERIGIYVVMFREISRTLLSIIVLFFYLILGFALSFYALMIEQQHFGRMFLSLLQTFVMMVGEMNYQDNFMKPYLQGDLPFPDLTLAIFVWFVLLVPILLMNLLIGLAVGDIAEVQTNACLKRIAMQIELHTNLEERLP 997
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Zebrafish
Match: ank2b (ankyrin 2b, neuronal [Source:ZFIN;Acc:ZDB-GENE-041010-165]) HSP 1 Score: 157.532 bits (397), Expect = 2.727e-38 Identity = 141/554 (25.45%), Postives = 234/554 (42.24%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNS---------YDD-------------------NGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLA 1828
N LH A+ N ++ +L + I+ K+ G T L A +SG+ V L+ ++G + + + G +P+ +A + + ++ VK LL + A D + LH H + KLLL + +P + NG +P+ +A ++ L I+ + I + G + A I+L L+ GA +++ G+ ALH+A+ G E++ L NG +++ + LH+ G + + LL + AH + N TPL +A E L +LL A L KK T LH+ G +E +LL Q + N YD+ NG PLH+A N +I L+ GA + +PIH A+++GH E+ L+ Q+ + + + LA Q + E L + + + + G L+ AC G+ MV +LK ++ + + TPLHQAAQ G T ++ LL GA+ T T L +A
Sbjct: 258 NGITPLHVASKRGNTNMVHLLLDRGAQIDAKTRDGLTPLHCAARSGHDTAVELLL-ERGAPMLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLIK--------YGAFIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETALHMAARAGQMEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATANGYTPLHIAAR-------EGHLDVTTVLLEAGAAHSLATKKGFTPLHVASKYGSLEVAKLLLQRRAPPDSAGKQNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNGYTPLHIAAKKNQMEIATTLLQYGAETNIQTKQGVMPIHLASQEGHSEMAALLLQRG-AQVNVTTKSGLTSLHLAAQEDKVGVGEILVKQGANLDQQTKLGYTPLIVACHYGNAKMVNFLLKSGASVNDKTKNGYTPLHQAAQQGNTHIINVLLQYGAKPNAITNGNTALAIA 794 HSP 2 Score: 139.428 bits (350), Expect = 1.213e-32 Identity = 138/540 (25.56%), Postives = 237/540 (43.89%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFL 1867
N N LH AA + +L++ +L + +++ + KG+TAL +A +G + V+++ K +G I+ Q + G TP+ +A + N +D+V+ LL G N + DG L ++ H +++ +LL +V+ + + +AA ++ L +Q+ N+ + S G++ A Y + L GA ++ G LH+AS+ G + ++ L D G I++ + + LH +G + E LL A + +N L+PL ++ +Q + + L DV L T LH+ GH +LL +K+ N+ NG PLH+AC N K+ LI GA + + PIH A GHL IV L+ N + N + +A ++G + L + ++ L A ++G +V+L+L+ + + TPLH AA+ G + LL GA T TPL +A AK+ L
Sbjct: 64 NGLNALHLAAKEGHVDLVQELLGRGSSVDSATKKGNTALHIASLAGQGDVVKILSK-RGANINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSIATEDGFTPLAIALQQGHNQVVSILLENDTKGKVR----LPALHIAARKDDTKSAALLLQNDHNADVQSKS--------GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVHLLLDRGAQIDAKTRDGLTPLHCAARSGHDTAVELLLERGAPMLARTKNGLSPL----HMAAQGDHVECVKHLLQHKAPVDDVTL---DYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRVKVMELLIKYGAFIQAITESGLTPIHVAAFMGHLNIVLLLLQ-NGASPDVSNIRGETALHMAARAGQMEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATANGYTPLHIAAREGHLDVTTVLLEAGAAHSLATKKGFTPLHVASKYGSLEVAKLLL 576 HSP 3 Score: 93.9745 bits (232), Expect = 9.532e-19 Identity = 106/440 (24.09%), Postives = 180/440 (40.91%), Query Frame = 2
Query: 782 SCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ---------------LIKEEEKQ-FLLNSYDDNGDY-------PLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG----------------NNILMYACQVGDIGM-----------------VKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMG 1930
+ FL A R +LE LK G DI + G NALH+A++ G +++ +L G +++S ++ALH+ G V + L A++N ++N TPL ++ E L ++ LL N + + + T L + + GH + + +L + K++ K LL D N D PLH+A + L++ GA + N P+H A+++G+ +V L+D QI + D + A +SGH E L + M ++ + G ++L + V D+ + KL+L K N R + TPLH A + + K++E L+ GA + T TP+ +A H N + L + + R +T HM
Sbjct: 34 TSFLRAARAGNIDKVLEYLKGGVDIGTSNQNGLNALHLAAKEGHVDLVQELLGRGSSVDSATKKGNTALHIASLAGQGDVVKILSKRGANINAQSQNGFTPLYMASQ-------ENHLDVVRYLLENGGNQSIATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVHLLLDRG-AQIDAKTRDGLTPLHCAARSGHDTAVELLLERGAPMLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLIKYGAFIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETA-LHMA 464 HSP 4 Score: 77.411 bits (189), Expect = 1.056e-13 Identity = 69/293 (23.55%), Postives = 122/293 (41.64%), Query Frame = 2
Query: 242 HPN----NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQ------------------SLMNSKINIASVINSTDCE-------GYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECL 1033
HP+ N + LH AA + ++ +L + + KG T L +A K G+ E +L+ +++ + G TP+ +A + + +LL GA+P + +G LH + N +E+ LL ++ G+ PI LA+ G+ E L +Q + K+ + ++ GY+ + A Y ++ LK GA +N G LH A++ G + II L G N++ N ++AL + G +SV + L
Sbjct: 515 HPDAATANGYTPLHIAAREGHLDVTTVLLEAGAAHSLATKKGFTPLHVASKYGSLEVAKLLLQRRAPPDSAGKQNGLTPLHVAAHYDNQKVALLLLDKGASPHATAKNGYTPLHIAAKKNQMEIATTLLQYGAETNIQTKQGVMPIHLASQEGHSEMAALLLQRGAQVNVTTKSGLTSLHLAAQEDKVGVGEILVKQGANLDQQTKLGYTPLIVACHYGNAKMVNFLLKSGASVNDKTKNGYTPLHQAAQQGNTHIINVLLQYGAKPNAITNG-NTALAIARRLGYISVVDTL 806
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Xenopus
Match: trpa1 (transient receptor potential cation channel, subfamily A, member 1 [Source:NCBI gene;Acc:100158526]) HSP 1 Score: 216.468 bits (550), Expect = 4.566e-57 Identity = 240/942 (25.48%), Postives = 427/942 (45.33%), Query Frame = 2
Query: 308 FILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGME-IDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLH----------AKCSPEVKDNN-GISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSV----DNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI-ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTG--KTHMGYIIMKNEDIANELLNRGL-EVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSR--------YTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSI--MSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMY-SSAIFFTAKVKDPMCT--IQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDP------GFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
F+L ++ + +T L A K GN + + +I + E I+ D +G TP+ A + N +D +K+LL GA+P + LH I+ H + ++ + + K N G PI + A +G L+ + ++ I IN T+ E S A++ ++ C+ YGA I+L Q++ ALH A+ G +EI+ + + + N + D N ++ LH + + +AE L+ A+++ ++ TPLL L + KS+ L L+ ADVKLKD + LHL++ G ++ + F ++ E + L++ D G PLH AC + + N L+ +L + N+ P+H A G + L+ + + DE + + LA ++GH I FL K + D G L YA G +K +L+ L + Q+T +H A + G K V LL GA + N + + A+ +T V + W+ ++ T K + +I + LL+R + E I D S + + +Y+F L P + R T + ++++ L+ HP+ LL KW +G + +L + L T +I + + P + Y + + M + MS+FG ++ E+++ QKL Y GSN + +Y SS IF ++ P+ +QW FG IA+ W N + YLQ ++GI I+MF ++ ++++I+ LF L++ + ++FY+ Q F +F+ + + M++G+++Y FL P + FT + + +F++LI I L+NL++G+AVGDI + +A + +Q++ + E LP
Sbjct: 32 FVLKNPGSLAARDDSEATPLHHAAKLGNIDLMLMIVNESAEEGINALDSRGNTPLHWAVQKNKLDCLKVLLCRGADPNIQNCYRLSPLHLAIQLFHNSIAEVRFFQGICFSLRTLGRGAKLCKQNKLGCYPIHMTAFMGSLKCMDIILKKGEEMGYTIDHHINFTNNEKSSPLHLAVQNGNIDVVKACISYGAKIDLRQSDNATALHFAATQGATEIVKFMVSSYSDDNKIVDLPDGNDETPLHKSVLFDHVELAEYLISEGANIDSEDKESRTPLL----LATSCSAWKSVNLL---LSKGADVKLKDHYGRNFLHLMVLQPGGLKNLNSEF--LQMENIKKLVSDEDCEGCTPLHYACRHGVPNSVNNLLGLNMSLYSKSKNKRSPLHFAACYGRFNTCQRLLRFMSDGRLLNDGDEKGMTPLHLAAENGHEKIV-FLLLKRGALLLSDHRGWTALHYAALSGYTRTIKTLLETSIGLIDKTDKEQNTAMHLAGREGHAKAVSLLLENGASILLNANGASYIHEAIRFGKKDTVLVSIQSERWEEILQTFSHTSSYKCAILEMIYHLPESFKTLLDRCMTESIGDKKSPDFHV-EYNFTYLQC-PLSFRKAHKRENNVHYEPLTTLNAMVQHQRIDLLSHPVCKEYLLMKWMAYGFKAHLLNLAIYSLGLIPLTLLIINAVRPESLDTQY--------------------TRVCMGLVFCMSLFG---IVKEAVQLCQQKLAYIGDGSNIIDWSIYISSIIFVSSLCHSPIVVSGLQWQFGAIAVFASWVNFLIYLQRFESYGIYIVMFWEILRTLLRIVFLFFFLILAFGLSFYVFLYPQVTFSRPYFALMQSFTMMLGDINYEEGFLKPLLDDQIEYPFFTFIH---LIMFTLLIPILLMNLLIGLAVGDIAEVQRNACLKRIAMQVSLHTSLEKKLP 935
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Xenopus
Match: trpa1 (transient receptor potential cation channel, subfamily A, member 1 [Source:NCBI gene;Acc:100158526]) HSP 1 Score: 214.542 bits (545), Expect = 1.965e-56 Identity = 256/988 (25.91%), Postives = 444/988 (44.94%), Query Frame = 2
Query: 236 ENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGME-IDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKC----------SPEV----KDNN-------------------GISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLC-----DNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI-ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTG--KTHMGYIIMKNEDIANELLNRGL-EVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSR--------YTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPD-YDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMY-SSAIFFTAKVKDPMCT--IQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDP------GFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
+++P F L+ E + + + F+L ++ + +T L A K GN + + +I + E I+ D +G TP+ A + N +D +K+LL GA+P + LH I+ H I L+LH+ +P + KDN+ G PI + A +G L+ + ++ I IN T+ E S A++ ++ C+ YGA I+L Q++ ALH A+ G +EI+ + DN I ++ D N ++ LH + + +AE L+ A+++ ++ TPLL L + KS+ L L+ ADVKLKD + LHL++ G ++ + F ++ E + L++ D G PLH AC + + N L+ +L + N+ P+H A G + L+ + + DE + + LA ++GH I FL K + D G L YA G +K +L+ L + Q+T +H A + G K V LL GA + N + + A+ +T V + W+ ++ T K + +I + LL+R + E I D S + + +Y+F L P + R T + ++++ L+ HP+ LL KW +G + +L + L T MI S D YD Q T + + MS+FG ++ E+++ QKL Y GSN + +Y SS IF ++ P+ +QW FG IA+ W N + YLQ ++GI I+MF ++ ++++I+ LF L++ + ++FY+ Q F +F+ + + M++G+++Y FL P + FT + + +F++LI I L+NL++G+AVGDI + +A + +Q++ + E LP
Sbjct: 33 DDNPLLIFKLIAEGNVCR---VRNFVLKNPGSLAARDDSEATPLHHAAKLGNIDLMLMIVNESAEEGINALDSRGNTPLHWAVQKNKLDCLKVLLCRGADPNIQNCYRLSPLHLAIQLFH-NSIALILHSTTDINLEGDLGNTPVMQACCKDNHEALNLLLGRGAKLCKQNKLGCYPIHMTAFMGSLKCMDIILKKGEEMGYTIDHHINFTNNEKSSPLHLAVQNGNIDVVKACISYGAKIDLRQSDNATALHFAATQGATEIVKFMVSSYSDDNKI-VDLPDGNDETPLHKSVLFDHVELAEYLISEGANIDSEDKESRTPLL----LATSCSAWKSVNLL---LSKGADVKLKDHYGRNFLHLMVLQPGGLKNLNSEF--LQMENIKKLVSDEDCEGCTPLHYACRHGVPNSVNNLLGLNMSLYSKSKNKRSPLHFAACYGRFNTCQRLLRFMSDGRLLNDGDEKGMTPLHLAAENGHEKIV-FLLLKRGALLLSDHRGWTALHYAALSGYTRTIKTLLETSIGLIDKTDKEQNTAMHLAGREGHAKAVSLLLENGASILLNANGASYIHEAIRFGKKDTVLVSIQSERWEEILQTFSHTSSYKCAILEMIYHLPESFKTLLDRCMTESIGDKKSPDFHV-EYNFTYLQC-PLSFRKAHKRENNVHYEPLTTLNAMVQHQRIDLLSHPVCKEYLLMKWMAYGFKAHLLNLAIYSLGLIPLTLMI---------SNDFYDTQ--------------YTRVCMGLVFCMSLFG---IVKEAVQLCQQKLAYIGDGSNIIDWSIYISSIIFVSSLCHSPIVVSGLQWQFGAIAVFASWVNFLIYLQRFESYGIYIVMFWEILRTLLRIVFLFFFLILAFGLSFYVFLYPQVTFSRPYFALMQSFTMMLGDINYEEGFLKPLLDDQIEYPFFTFIH---LIMFTLLIPILLMNLLIGLAVGDIAEVQRNACLKRIAMQVSLHTSLEKKLP 974
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Xenopus
Match: trpa1 (transient receptor potential cation channel, subfamily A, member 1 [Source:NCBI gene;Acc:100158526]) HSP 1 Score: 214.542 bits (545), Expect = 2.288e-56 Identity = 258/1007 (25.62%), Postives = 455/1007 (45.18%), Query Frame = 2
Query: 236 ENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGME-IDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIK-LLLHAKC----------SPEV----KDNN-------------------GISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLC-----DNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI-ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTG--KTHMGYIIMKNEDIANELLNRGL-EVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSR--------YTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIA----------DSPDYDN----QGCPVDNSTDNKLKSLTDSEITMNSI-----MSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMY-SSAIFFTAKVKDPMCT--IQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDP------GFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
+++P F L+ E + + + F+L ++ + +T L A K GN + + +I + E I+ D +G TP+ A + N +D +K+LL GA+P + LH I+ H + + L+LH+ +P + KDN+ G PI + A +G L+ + ++ I IN T+ E S A++ ++ C+ YGA I+L Q++ ALH A+ G +EI+ + DN I ++ D N ++ LH + + +AE L+ A+++ ++ TPLL L + KS+ L L+ ADVKLKD + LHL++ G ++ + F ++ E + L++ D G PLH AC + + N L+ +L + N+ P+H A G + L+ + + DE + + LA ++GH I FL K + D G L YA G +K +L+ L + Q+T +H A + G K V LL GA + N + + A+ +T V + W+ ++ T K + +I + LL+R + E I D S + + +Y+F L P + R T + ++++ L+ HP+ LL KW +G + +L + L T +I + + P + D+ N Q C + S L L D++ T + MS+FG ++ E+++ QKL Y GSN + +Y SS IF ++ P+ +QW FG IA+ W N + YLQ ++GI I+MF ++ ++++I+ LF L++ + ++FY+ Q F +F+ + + M++G+++Y FL P + FT + + +F++LI I L+NL++G+AVGDI + +A + +Q++ + E LP
Sbjct: 33 DDNPLLIFKLIAEGNVCR---VRNFVLKNPGSLAARDDSEATPLHHAAKLGNIDLMLMIVNESAEEGINALDSRGNTPLHWAVQKNKLDCLKVLLCRGADPNIQNCYRLSPLHLAIQLFHNSIAEALILHSTTDINLEGDLGNTPVMQACCKDNHEALNLLLGRGAKLCKQNKLGCYPIHMTAFMGSLKCMDIILKKGEEMGYTIDHHINFTNNEKSSPLHLAVQNGNIDVVKACISYGAKIDLRQSDNATALHFAATQGATEIVKFMVSSYSDDNKI-VDLPDGNDETPLHKSVLFDHVELAEYLISEGANIDSEDKESRTPLL----LATSCSAWKSVNLL---LSKGADVKLKDHYGRNFLHLMVLQPGGLKNLNSEF--LQMENIKKLVSDEDCEGCTPLHYACRHGVPNSVNNLLGLNMSLYSKSKNKRSPLHFAACYGRFNTCQRLLRFMSDGRLLNDGDEKGMTPLHLAAENGHEKIV-FLLLKRGALLLSDHRGWTALHYAALSGYTRTIKTLLETSIGLIDKTDKEQNTAMHLAGREGHAKAVSLLLENGASILLNANGASYIHEAIRFGKKDTVLVSIQSERWEEILQTFSHTSSYKCAILEMIYHLPESFKTLLDRCMTESIGDKKSPDFHV-EYNFTYLQC-PLSFRKAHKRENNVHYEPLTTLNAMVQHQRIDLLSHPVCKEYLLMKWMAYGFKAHLLNLAIYSLGLIPLTLLIINAVRPESLAIIEECEHLKRTDFYNSSMKQEC-ANVSRKLDLLQLKDTQYTRVCMGLVFCMSLFG---IVKEAVQLCQQKLAYIGDGSNIIDWSIYISSIIFVSSLCHSPIVVSGLQWQFGAIAVFASWVNFLIYLQRFESYGIYIVMFWEILRTLLRIVFLFFFLILAFGLSFYVFLYPQVTFSRPYFALMQSFTMMLGDINYEEGFLKPLLDDQIEYPFFTFIH---LIMFTLLIPILLMNLLIGLAVGDIAEVQRNACLKRIAMQVSLHTSLEKKLP 1016
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Xenopus
Match: trpa1 (transient receptor potential cation channel, subfamily A, member 1 [Source:NCBI gene;Acc:100158526]) HSP 1 Score: 209.534 bits (532), Expect = 8.218e-55 Identity = 247/992 (24.90%), Postives = 448/992 (45.16%), Query Frame = 2
Query: 236 ENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGME-IDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIK-LLLHAKC----------SPEV----KDNN-------------------GISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLC-----DNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI-ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEF-----RFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSR--------YTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSI--MSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMY-SSAIFFTAKVKDPMCT--IQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDP------GFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
+++P F L+ E + + + F+L ++ + +T L A K GN + + +I + E I+ D +G TP+ A + N +D +K+LL GA+P + LH I+ H + + L+LH+ +P + KDN+ G PI + A +G L+ + ++ I IN T+ E S A++ ++ C+ YGA I+L Q++ ALH A+ G +EI+ + DN I ++ D N ++ LH + + +AE L+ A+++ ++ TPLL L + KS+ L L+ ADVKLKD + LHL++ G ++ + F ++ E + L++ D G PLH AC + + N L+ +L + N+ P+H A G + L+ + + DE + + LA ++GH I FL K + D G L YA G +K +L+ L + Q+T +H A + G K V LL GA + N + + A+ +T V + W+ ++ +K M Y + ++ + +LN +++Y+F L P + R T + ++++ L+ HP+ LL KW +G + +L + L T +I + + P + + + + + ++ +K E M + MS+FG ++ E+++ QKL Y GSN + +Y SS IF ++ P+ +QW FG IA+ W N + YLQ ++GI I+MF ++ ++++I+ LF L++ + ++FY+ Q F +F+ + + M++G+++Y FL P + FT + + +F++LI I L+NL++G+AVGDI + +A + +Q++ + E LP
Sbjct: 33 DDNPLLIFKLIAEGNVCR---VRNFVLKNPGSLAARDDSEATPLHHAAKLGNIDLMLMIVNESAEEGINALDSRGNTPLHWAVQKNKLDCLKVLLCRGADPNIQNCYRLSPLHLAIQLFHNSIAEALILHSTTDINLEGDLGNTPVMQACCKDNHEALNLLLGRGAKLCKQNKLGCYPIHMTAFMGSLKCMDIILKKGEEMGYTIDHHINFTNNEKSSPLHLAVQNGNIDVVKACISYGAKIDLRQSDNATALHFAATQGATEIVKFMVSSYSDDNKI-VDLPDGNDETPLHKSVLFDHVELAEYLISEGANIDSEDKESRTPLL----LATSCSAWKSVNLL---LSKGADVKLKDHYGRNFLHLMVLQPGGLKNLNSEF--LQMENIKKLVSDEDCEGCTPLHYACRHGVPNSVNNLLGLNMSLYSKSKNKRSPLHFAACYGRFNTCQRLLRFMSDGRLLNDGDEKGMTPLHLAAENGHEKIV-FLLLKRGALLLSDHRGWTALHYAALSGYTRTIKTLLETSIGLIDKTDKEQNTAMHLAGREGHAKAVSLLLENGASILLNANGASYIHEAIRFGKKDTVLVSIQSERWEEILQTFSHTSSYKCAILEMIYHLPESFKVG--ILN---------------VSQYNFTYLQC-PLSFRKAHKRENNVHYEPLTTLNAMVQHQRIDLLSHPVCKEYLLMKWMAYGFKAHLLNLAIYSLGLIPLTLLIINAVRPESLAIIEECEHLKRTDFYNSSMK----QEFCMGLVFCMSLFG---IVKEAVQLCQQKLAYIGDGSNIIDWSIYISSIIFVSSLCHSPIVVSGLQWQFGAIAVFASWVNFLIYLQRFESYGIYIVMFWEILRTLLRIVFLFFFLILAFGLSFYVFLYPQVTFSRPYFALMQSFTMMLGDINYEEGFLKPLLDDQIEYPFFTFIH---LIMFTLLIPILLMNLLIGLAVGDIAEVQRNACLKRIAMQVSLHTSLEKKLP 982
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Xenopus
Match: trpa1 (transient receptor potential cation channel, subfamily A, member 1 [Source:NCBI gene;Acc:100158526]) HSP 1 Score: 204.142 bits (518), Expect = 4.335e-53 Identity = 247/963 (25.65%), Postives = 426/963 (44.24%), Query Frame = 2
Query: 308 FILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGME-IDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKC----------SPEV----KDNN-------------------GISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLC-----DNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI-ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTG--KTHMGYIIMKNEDIANELLNRGL-EVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSR--------YTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMY-SSAIFFTAKVKDPMCT--IQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDP------GFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
F+L ++ + +T L A K GN + + +I + E I+ D +G TP+ A + N +D +K+LL GA+P + LH I+ H I L+LH+ +P + KDN+ G PI + A +G L+ + ++ I IN T+ E S A++ ++ C+ YGA I+L Q++ ALH A+ G +EI+ + DN I ++ D N ++ LH + + +AE L+ A+++ ++ TPLL L + KS+ L L+ ADVKLKD + LHL++ G ++ + F ++ E + L++ D G PLH AC + + N L+ +L + N+ P+H A G + L+ + + DE + + LA ++GH I FL K + D G L YA G +K +L+ L + Q+T +H A + G K V LL GA + N + + A+ +T V + W+ ++ T K + +I + LL+R + E I D S + + +Y+F L P + R T + ++++ L+ HP+ LL KW +G + +L + L T MI N L I +FG ++ E+++ QKL Y GSN + +Y SS IF ++ P+ +QW FG IA+ W N + YLQ ++GI I+MF ++ ++++I+ LF L++ + ++FY+ Q F +F+ + + M++G+++Y FL P + FT + + +F++LI I L+NL++G+AVGDI + +A + +Q++ + E LP
Sbjct: 32 FVLKNPGSLAARDDSEATPLHHAAKLGNIDLMLMIVNESAEEGINALDSRGNTPLHWAVQKNKLDCLKVLLCRGADPNIQNCYRLSPLHLAIQLFH-NSIALILHSTTDINLEGDLGNTPVMQACCKDNHEALNLLLGRGAKLCKQNKLGCYPIHMTAFMGSLKCMDIILKKGEEMGYTIDHHINFTNNEKSSPLHLAVQNGNIDVVKACISYGAKIDLRQSDNATALHFAATQGATEIVKFMVSSYSDDNKI-VDLPDGNDETPLHKSVLFDHVELAEYLISEGANIDSEDKESRTPLL----LATSCSAWKSVNLL---LSKGADVKLKDHYGRNFLHLMVLQPGGLKNLNSEF--LQMENIKKLVSDEDCEGCTPLHYACRHGVPNSVNNLLGLNMSLYSKSKNKRSPLHFAACYGRFNTCQRLLRFMSDGRLLNDGDEKGMTPLHLAAENGHEKIV-FLLLKRGALLLSDHRGWTALHYAALSGYTRTIKTLLETSIGLIDKTDKEQNTAMHLAGREGHAKAVSLLLENGASILLNANGASYIHEAIRFGKKDTVLVSIQSERWEEILQTFSHTSSYKCAILEMIYHLPESFKTLLDRCMTESIGDKKSPDFHV-EYNFTYLQC-PLSFRKAHKRENNVHYEPLTTLNAMVQHQRIDLLSHPVCKEYLLMKWMAYGFKAHLLNLAIYSLGLIPLTLMI------------------------SNDFYVL---------IQLLFG---IVKEAVQLCQQKLAYIGDGSNIIDWSIYISSIIFVSSLCHSPIVVSGLQWQFGAIAVFASWVNFLIYLQRFESYGIYIVMFWEILRTLLRIVFLFFFLILAFGLSFYVFLYPQVTFSRPYFALMQSFTMMLGDINYEEGFLKPLLDDQIEYPFFTFIH---LIMFTLLIPILLMNLLIGLAVGDIAEVQRNACLKRIAMQVSLHTSLEKKLP 941
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Mouse
Match: Trpa1 (transient receptor potential cation channel, subfamily A, member 1 [Source:MGI Symbol;Acc:MGI:3522699]) HSP 1 Score: 187.578 bits (475), Expect = 7.183e-48 Identity = 229/970 (23.61%), Postives = 421/970 (43.40%), Query Frame = 2
Query: 224 QYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCK--------GSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYD-GMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN----INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGH----IETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMR-NHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHF---FMLDAGPYD----SASVNSRYTEFMTI----AKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGC--PVDNSTDNKLKSLTDSEITMNSIM----SMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKV-KDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFK---IFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
+Y DEN LH AA EL+E I IN SC+ G+T L A + E V+ + Q G + ++R +P+ +A +++K+L + A + E + G L ++ E +++LL + G P+ AA G + L + + + + IN + + S A++ +I CL GA I++ +N ALH A+ G ++I+ + + +N+VD N ++ LH +AE L+ A +N + +PL+ + S + LLL A V +KD + LHL + + + + Q IKE L+ D++G PLH AC + N L+ ++ + ++ P+H A G + + L+ +I + NE + + + LA ++GH + + L K + D G L +A G +K+IL + R + +T LH AA+ G K V LLS A++ N + L +AL N+ + + W ++ F IM+ + E + L+ ++ +KS YH F P A E +TI ++ + +L+ HP+ LL KW +G M +L ++ L T ++ P +A +++ G ++ + ++ +L I + I+ S+FG+ + E ++ QK YF +N + ++Y+++I F + + +QW G IAI W N + YLQ N GI I+M + + ++++ +F+ L++ + ++FY++ Q F S + + M++G+++Y FL+P F+ + + + F++ + I L+NL++G+AVGDI + A + +Q+ + E LP
Sbjct: 59 KYEDEN-----LCPLHHAAAEGQVELMELI------INGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFLLSQ-GANPNLRNRNMMSPLHIAVHGMYNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKKCMELILAYGEKNGYSRETHINFVNHKKASPLHLAVQSGDLDMIKMCLDNGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVDGNQETLLHRASLFDHHDLAEYLISVGADINSTDSEGRSPLILAT-------ASASWNIVNLLLCKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFMQMQHIKE-----LVMDEDNDGCTPLHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQ-DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL-LKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTIRNKRWDECLQV-FTHNSPSNRCPIMEMVEYLPECMKVLLDFCMIPSTEDKSCQDYHIEYNFKYLQCPLSMTKKVAPTQDVVYEPLTILNVMVQHNRIELLNHPVCREYLLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMA----FNSTGIINGTSSTHEERIDTLNSFPIKICMILVFLSSIFGYCK---EVIQIFQQKRNYFLDYNNALEWVIYTTSIIFVLPLFLNIPAYMQWQCGAIAIFFYWMNFLLYLQRFENCGIFIVMLEVIFKTLLRSTGVFIFLLLAFGLSFYVLLNFQDAFSTPLLSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTNLEKKLP 994
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Mouse
Match: Trpa1 (transient receptor potential cation channel, subfamily A, member 1 [Source:MGI Symbol;Acc:MGI:3522699]) HSP 1 Score: 171.4 bits (433), Expect = 6.694e-43 Identity = 224/964 (23.24%), Postives = 398/964 (41.29%), Query Frame = 2
Query: 302 LEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEI-DGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKC---------------SPEVKDNN-------------------GISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN----INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGH----IETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMR-NHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHF---FMLDAGPYD----SASVNSRYTEFMTI----AKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKV-KDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFK---IFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
LE + + ++K + L A G E + LI E+ + D G TP+ A N ++ VK LL GANP + M LH + + E+IK+L K S KDN+ G P+ AA G + L + + + + IN + + S A++ +I CL GA I++ +N ALH A+ G ++I+ + + +N+VD N ++ LH +AE L+ A +N + +PL+ + S + LLL A V +KD + LHL + + + + Q IKE L+ D++G PLH AC + N L+ ++ + ++ P+H A G + + L+ +I + NE + + + LA ++GH + + L K + D G L +A G +K+IL + R + +T LH AA+ G K V LLS A++ N + L +AL N+ + + W ++ F IM+ + E + L+ ++ +KS YH F P A E +TI ++ + +L+ HP+ LL KW +G M +L ++ L T ++ P +A +++ G + N T + + D + K YF +N + ++Y+++I F + + +QW G IAI W N + YLQ N GI I+M + + ++++ +F+ L++ + ++FY++ Q F S + + M++G+++Y FL+P F+ + + + F++ + I L+NL++G+AVGDI + A + +Q+ + E LP
Sbjct: 47 LEDFIKNRRKLSKYEDENLCPLHHAAAEGQVELMELIINGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFLLSQGANPNLRNRNMMSPLHIAVHGMYNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKKCMELILAYGEKNGYSRETHINFVNHKKASPLHLAVQSGDLDMIKMCLDNGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVDGNQETLLHRASLFDHHDLAEYLISVGADINSTDSEGRSPLILAT-------ASASWNIVNLLLCKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFMQMQHIKE-----LVMDEDNDGCTPLHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQ-DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL-LKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTIRNKRWDECLQV-FTHNSPSNRCPIMEMVEYLPECMKVLLDFCMIPSTEDKSCQDYHIEYNFKYLQCPLSMTKKVAPTQDVVYEPLTILNVMVQHNRIELLNHPVCREYLLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMA----FNSTG--IINGTSSTHEERID-------------------------TLKRNYFLDYNNALEWVIYTTSIIFVLPLFLNIPAYMQWQCGAIAIFFYWMNFLLYLQRFENCGIFIVMLEVIFKTLLRSTGVFIFLLLAFGLSFYVLLNFQDAFSTPLLSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTNLEKKLP 964
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]) HSP 1 Score: 169.088 bits (427), Expect = 9.739e-42 Identity = 136/512 (26.56%), Postives = 233/512 (45.51%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE 1786
N LH A+ N +++ +L + I+ K+ G T L A +SG+ + V L+ ++K + + + G +P+ +A + + ++ VK LL Y A D + LH H + KLLL + +P + NG +P+ +A ++ L ++ + + S + + LN I+L L+ GA ++ G+ ALH+A+ G E++ L NG +++ + LH+ G + + LL + AH + N TPL SA Q+ V L L A L KK T LH+ G ++ +LL Q ++ +S NG PLH+A N +I + L++ GA P+H A+++GH ++V L+D I + + + LA Q N+ + L + + + G L+ AC G++ MV +LK+ N+ + + TPLHQAAQ G T ++ LL GA+
Sbjct: 244 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKA-PLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLN--------IVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISARE-GQVDVASVL------LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQ------RRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKG-ANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAK 732 HSP 2 Score: 165.622 bits (418), Expect = 1.034e-40 Identity = 166/607 (27.35%), Postives = 272/607 (44.81%), Query Frame = 2
Query: 230 IDENHPN-NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE-DIANELLNRGLEVISDTNSVNKS-LTKYHF 2038
ID N N N N LH AA + L++ +L + +++ + KG+TAL +A +G AE V+++ K+ G I+ Q + G TP+ +A + N ID+VK LL GAN + DG L ++ H + + +LL +V+ + + +AA ++ L +Q+ N+ + ++N T G++ A Y + L GA ++ G LH+AS+ G + ++ L D G I++ + + LH +G V E LL A + +N L+PL ++ +Q + + L DV L T LH+ GH +LL +K+ N+ NG PLH+AC N K+ L+ GA++ + PIH A GHL IV L+ N + N + +A ++G + L + ++ L A ++G +V+L+L+ + + TPLH +A+ GQ + LL GA T TPL +A + AK+ L ++ K G T + KN+ IA+ LLN G E TN+V K +T H
Sbjct: 34 IDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKE-GANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVR----LPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPL----HMAAQGDHVECVKHLLQYKAPVDDVTL---DYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ-NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAG---KNGYTPLHIAAKKNQMQIASTLLNYGAE----TNTVTKQGVTPLHL 614 HSP 3 Score: 114.005 bits (284), Expect = 7.314e-25 Identity = 112/465 (24.09%), Postives = 191/465 (41.08%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMV 1660
LH AA + + + +L K+ N N ++ G T L +A K + + L+ K G I G TPI +A + ++IV +LL GA+P + G LH R+ +E+++ LL + + +P+ +A+ LG E L +Q + + ++ GY+ + R Q + L+ GA +LA +G LH+A++ G ++ L +S N + LH+ + +A LL A N + +TPL +L SQ G + L L+ A++ + K T LHL + ++L + + + +Y G PL VAC K+ N+L+ +GAN+ N P+H+A Q GH +I L + ++ GN L A ++G I +V
Sbjct: 348 LHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKY-GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHP--------DAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPL----HLASQEGHTDMVTLL---LDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRD------AYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAA----------------------------------QQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 756 HSP 4 Score: 101.679 bits (252), Expect = 4.098e-21 Identity = 105/448 (23.44%), Postives = 185/448 (41.29%), Query Frame = 2
Query: 782 SCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ--------------------------LIKEE-----EKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG----------------NNILMYACQVGDIGM-----------------VKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMG 1930
+ FL A R ++E LK G DIN G NALH+A++ G ++ +L G +++S ++ALH+ G V + L+ A++N ++N TPL +A E + +K LL N A+ + T L + + GH + + +L + L++ + + + ++N ++G PLH+A + L++ GA + N P+H A+++G+ +VK L+D QI + D + A +SGH + E L + + ++ + G ++L Y V D+ + KL+L K N R + TPLH A + + K++E L+ GA + T TP+ +A H N + L + + R +T HM
Sbjct: 12 ASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQ-------ENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG-GQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETA-LHMA 450 HSP 5 Score: 96.6709 bits (239), Expect = 1.312e-19 Identity = 121/502 (24.10%), Postives = 221/502 (44.02%), Query Frame = 2
Query: 356 STALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIR--YKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN--------INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTF-HQTPLTLA 1828
+ + L A ++GN + V K G++I+ ++ G + LA + + +V+ LL G++ + G LH + E++K+L+ + + NG +P+ +AA +++ ++ L+ + N ++ +G++ A++ + Q IL + L ALHIA+ ++ L N N +N + + LH+ H G+++VA LL A V+ RN +TPL ++ S+ G + +KLLL+ + K + T LH SGH + +ELL E++ L + NG PLH+A + + +L+ A + + +H A GH + K L+D R + + +A + + E L + + E+G + A +G + +V L+L+ + + N T LH AA+AGQ ++V LL GA + QTPL +A
Sbjct: 11 NASFLRAARAGNLDKVVEYLK-GGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDV----VKYLLENGANQSTATE----DGFTPLAVALQQGHNQAVAILLENDTKGKVRLP------ALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPL----HVASKRG---NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL------ERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANP-NARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIA 483 HSP 6 Score: 69.3218 bits (168), Expect = 2.916e-11 Identity = 61/260 (23.46%), Postives = 106/260 (40.77%), Query Frame = 2
Query: 242 HPN----NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAAS----------------------LGYLEAFYLCIQ---SLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL 934
HP+ N + LH +A ++ +L + + KG T L +A K G+ + +L+ +++ D + G TP+ +A + N + I LL YGA G+ LH + H +M+ LLL + + +G++ + LAA LGY C ++N + + +N+ GY+ A + II L++GA N G AL IA +G+ ++ L
Sbjct: 501 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA-DSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 759
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]) HSP 1 Score: 160.999 bits (406), Expect = 3.329e-39 Identity = 140/545 (25.69%), Postives = 238/545 (43.67%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG------------NNI---------------------LMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE 1786
N LH A+ N +++ +L + I+ K+ G T L A +SG+ + V L+ ++K + + + G +P+ +A + + ++ VK LL Y A D + LH H + KLLL + +P + NG +P+ +A ++ L ++ + + S + + LN I+L L+ GA ++ G+ ALH+A+ G E++ L NG +++ + LH+ G + + LL + AH + N TPL SA Q+ V L L A L KK T LH+ G ++ +LL Q ++ +S NG PLHVA + +K+ L+ +GA+ N P+H A +K ++I L++ + T+ + L LA Q GH ++ L K +H ++G N+ L+ AC G++ MV +LK+ N+ + + TPLHQAAQ G T ++ LL GA+
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKA-PLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLN--------IVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISARE-GQVDVASVL------LEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQ------RRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLH-LASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAK 786 HSP 2 Score: 157.147 bits (396), Expect = 4.460e-38 Identity = 148/548 (27.01%), Postives = 247/548 (45.07%), Query Frame = 2
Query: 230 IDENHPN-NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFL 1867
ID N N N N LH AA + L++ +L + +++ + KG+TAL +A +G AE V+++ K+ G I+ Q + G TP+ +A + N ID+VK LL GAN + DG L ++ H + + +LL +V+ + + +AA ++ L +Q+ N+ + ++N T G++ A Y + L GA ++ G LH+AS+ G + ++ L D G I++ + + LH +G V E LL A + +N L+PL ++ +Q + + L DV L T LH+ GH +LL +K+ N+ NG PLH+AC N K+ L+ GA++ + PIH A GHL IV L+ N + N + +A ++G + L + ++ L A ++G +V+L+L+ + + TPLH +A+ GQ + LL GA T TPL +A + AK+ L
Sbjct: 55 IDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKE-GANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVR----LPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPL----HMAAQGDHVECVKHLLQYKAPVDDVTL---DYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ-NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLL 583 HSP 3 Score: 108.612 bits (270), Expect = 3.035e-23 Identity = 119/492 (24.19%), Postives = 198/492 (40.24%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLF-----------------QLIKEEEKQFLLN----------SYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMV 1660
LH AA + + + +L K+ N N ++ G T L +A K + + L+ K G I G TPI +A + ++IV +LL GA+P + G LH R+ +E+++ LL + + +P+ +A+ LG E L +Q + + ++ GY+ + R Q + L+ GA +LA +G LH+A++ G ++ L +S N + LH+ H + VA LL A + +N TPL +A +Q+ + +L LN A+ K+ T LHL GH + + LL L +E+K + + +Y G PL VAC K+ N+L+ +GAN+ N P+H+A Q GH +I L + ++ GN L A ++G I +V
Sbjct: 369 LHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKY-GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHP--------DAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKK-NQMQIASTL------LNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAA----------------------------------QQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 810 HSP 4 Score: 101.679 bits (252), Expect = 4.172e-21 Identity = 105/448 (23.44%), Postives = 185/448 (41.29%), Query Frame = 2
Query: 782 SCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ--------------------------LIKEE-----EKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG----------------NNILMYACQVGDIGM-----------------VKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMG 1930
+ FL A R ++E LK G DIN G NALH+A++ G ++ +L G +++S ++ALH+ G V + L+ A++N ++N TPL +A E + +K LL N A+ + T L + + GH + + +L + L++ + + + ++N ++G PLH+A + L++ GA + N P+H A+++G+ +VK L+D QI + D + A +SGH + E L + + ++ + G ++L Y V D+ + KL+L K N R + TPLH A + + K++E L+ GA + T TP+ +A H N + L + + R +T HM
Sbjct: 33 ASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQ-------ENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG-GQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETA-LHMA 471 HSP 5 Score: 100.138 bits (248), Expect = 1.274e-20 Identity = 127/533 (23.83%), Postives = 233/533 (43.71%), Query Frame = 2
Query: 263 LLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIR--YKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN--------INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTF-HQTPLTLA 1828
+++E A K+ +F S + K + + L A ++GN + V K G++I+ ++ G + LA + + +V+ LL G++ + G LH + E++K+L+ + + NG +P+ +AA +++ ++ L+ + N ++ +G++ A++ + Q IL + L ALHIA+ ++ L N N +N + + LH+ H G+++VA LL A V+ RN +TPL ++ S+ G + +KLLL+ + K + T LH SGH + +ELL E++ L + NG PLH+A + + +L+ A + + +H A GH + K L+D R + + +A + + E L + + E+G + A +G + +V L+L+ + + N T LH AA+AGQ ++V LL GA + QTPL +A
Sbjct: 1 MMNEDAAQKSDSGEKFNGSSQRRKRPKKSDSNASFLRAARAGNLDKVVEYLK-GGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDV----VKYLLENGANQSTATE----DGFTPLAVALQQGHNQAVAILLENDTKGKVRLP------ALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPL----HVASKRG---NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL------ERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANP-NARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIA 504 HSP 6 Score: 70.4774 bits (171), Expect = 1.486e-11 Identity = 65/287 (22.65%), Postives = 121/287 (42.16%), Query Frame = 2
Query: 242 HPN----NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECL-KYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPL 1087
HP+ N + LH +A ++ +L + + KG T L +A K G+ + +L+ +++ D + G TP+ +A + + +LL GA+P + +G LH + N +++ LL+ G++P+ LA+ G+ + L + N ++ S + S L+ + + + + L K+GAD + G L +A G +++ L G N+N+ N + LH G + LL + A N N T L
Sbjct: 522 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAA-DSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTS---------LHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTAL 798 HSP 7 Score: 67.781 bits (164), Expect = 8.166e-11 Identity = 60/251 (23.90%), Postives = 101/251 (40.24%), Query Frame = 2
Query: 257 FNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAAS----------------------LGYLEAFYLCIQ---SLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL 934
F LH AA + ++ + +L ++ + G T L +A N + V L+ +KG + G TP+ +A + N + I LL YGA G+ LH + H +M+ LLL + + +G++ + LAA LGY C ++N + + +N+ GY+ A + II L++GA N G AL IA +G+ ++ L
Sbjct: 564 FTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQK-VALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 813
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]) HSP 1 Score: 156.377 bits (394), Expect = 3.762e-38 Identity = 138/545 (25.32%), Postives = 236/545 (43.30%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG---------------------------------NNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE 1786
N LH A+ N +++ +L + I+ K+ G T L A +SG+ + V L+ ++K + + + G +P+ +A + + ++ VK LL Y A D + LH H + KLLL + +P + NG +P+ +A ++ L ++ + + S + + LN I+L L+ GA ++ G+ ALH+A+ G E++ L NG +++ + LH+ G + + LL + AH + N TPL SA E + +LL A L KK T LH+ G ++ +LL Q ++ +S NG PLHVA + +K+ L+ +GA+ N P+H A +K ++I L++ + T+ + L LA Q GH ++ L K +H ++G L+ AC G++ MV +LK+ N+ + + TPLHQAAQ G T ++ LL GA+
Sbjct: 244 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKA-PLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLN--------IVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAR-------EGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQ------RRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLH-LASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAK 765 HSP 2 Score: 154.451 bits (389), Expect = 1.313e-37 Identity = 165/629 (26.23%), Postives = 271/629 (43.08%), Query Frame = 2
Query: 251 NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLN-----DNNWKNTM-------------------------EFRFKTGKTHMGYIIMKNE-DIANELLNRGLEVISDTNSVNK-SLTKYHF 2038
N N LH AA + L++ +L + +++ + KG+TAL +A +G AE V+++ K+ G I+ Q + G TP+ +A + N ID+VK LL GAN + DG L ++ H + + +LL +V+ + + +AA ++ L +Q+ N+ + ++N T G++ A Y + L GA ++ G LH+AS+ G + ++ L D G I++ + + LH +G V E LL A + +N L+PL ++ +Q + + L DV L T LH+ GH +LL +K+ N+ NG PLH+AC N K+ L+ GA++ + PIH A GHL IV L+ N + N + +A ++G + L + ++ L A ++G +V+L+L+ + + TPLH +A+ GQ + LL GA T TPL +A + AK+ L D+ KN + K G T + KN+ IA+ LLN G E TN+V K +T H
Sbjct: 42 NGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKE-GANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVR----LPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPL----HMAAQGDHVECVKHLLQYKAPVDDVTL---DYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQ-NGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAE----TNTVTKQGVTPLHL 647 HSP 3 Score: 105.145 bits (261), Expect = 2.763e-22 Identity = 119/492 (24.19%), Postives = 198/492 (40.24%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLF-----------------QLIKEEEKQFLLN----------SYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMV 1660
LH AA + + + +L K+ N N ++ G T L +A K + + L+ K G I G TPI +A + ++IV +LL GA+P + G LH R+ +E+++ LL + + +P+ +A+ LG E L +Q + + ++ GY+ + R Q + L+ GA +LA +G LH+A++ G ++ L +S N + LH+ H + VA LL A + +N TPL +A +Q+ + +L LN A+ K+ T LHL GH + + LL L +E+K + + +Y G PL VAC K+ N+L+ +GAN+ N P+H+A Q GH +I L + ++ GN L A ++G I +V
Sbjct: 348 LHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKY-GASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHP--------DAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAK-KNQMQIASTL------LNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQA----------------------------------AQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVV 789 HSP 4 Score: 98.5969 bits (244), Expect = 2.618e-20 Identity = 106/435 (24.37%), Postives = 182/435 (41.84%), Query Frame = 2
Query: 782 SCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSA--NLISQI------GVEKSLA----------FLKXXXXXXADVKLKDKKKQTI----LHLLIASGHIETIELLFQLIKEEEKQ--FLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG----------------NNILMYACQVGDIGM-----------------VKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKT 1912
+ FL A R ++E LK G DIN G NALH+A++ G ++ +L G +++S ++ALH+ G V + L+ A++N ++N TPL +A N I + G +S A L+ N + L++ K + LH+ ++ LL Q + Q ++N ++G PLH+A + L++ GA + N P+H A+++G+ +VK L+D QI + D + A +SGH + E L + + ++ + G ++L Y V D+ + KL+L K N R + TPLH A + + K++E L+ GA + T TP+ +A H N + L + + R +T
Sbjct: 12 ASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG-GQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGET 445 HSP 5 Score: 92.4337 bits (228), Expect = 2.083e-18 Identity = 151/643 (23.48%), Postives = 266/643 (41.37%), Query Frame = 2
Query: 362 ALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIR--YKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN--------INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVA-------CSNNL--------------------------RKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLI--DLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMK--NEDIANELLNRGLEVISDTNSVNKSLTKYH-----------FFMLDAGPYDSASVNSRYTEFMTIAK 2113
+ L A ++GN + V K G++I+ ++ G + LA + + +V+ LL G++ + G LH + E++K+L+ + + NG +P+ +AA +++ ++ L+ + N ++ +G++ A++ + Q IL + L ALHIA+ ++ L N N +N + + LH+ H G+++VA LL A V+ RN +TPL ++ S+ G + +KLLL+ + K + T LH SGH + +ELL E++ L + NG PLH+A C +L ++ L+ + AN N P+H A +K +++++ L+ +IQ IT E I +A GH NI L + G L A + G + +V+ +L+ + R + TPLH A++ G+T++V+ LL A T + TPL ++ + A V L + K G T + ++ K + D+A LL R +D+ N LT H +L+ G A+ + YT AK
Sbjct: 13 SFLRAARAGNLDKVVEYLK-GGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHID----VVKYLLENGANQSTATE----DGFTPLAVALQQGHNQAVAILLENDTKGKVRLP------ALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPL----HVASKRG---NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLL------ERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAIT---ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHS---LATKKGFTPL-HVAAKYGSLDVAKLLLQR--RAAADSAGKN-GLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAK 617 HSP 6 Score: 66.2402 bits (160), Expect = 2.201e-10 Identity = 65/287 (22.65%), Postives = 121/287 (42.16%), Query Frame = 2
Query: 242 HPN----NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECL-KYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPL 1087
HP+ N + LH +A ++ +L + + KG T L +A K G+ + +L+ +++ D + G TP+ +A + + +LL GA+P + +G LH + N +++ LL+ G++P+ LA+ G+ + L + N ++ S + S L+ + + + + L K+GAD + G L +A G +++ L G N+N+ N + LH G + LL + A N N T L
Sbjct: 501 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAA-ADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTS---------LHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTAL 777 HSP 7 Score: 65.4698 bits (158), Expect = 3.423e-10 Identity = 60/251 (23.90%), Postives = 101/251 (40.24%), Query Frame = 2
Query: 257 FNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAAS----------------------LGYLEAFYLCIQS---LMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL 934
F LH AA + ++ + +L ++ + G T L +A N + V L+ +KG + G TP+ +A + N + I LL YGA G+ LH + H +M+ LLL + + +G++ + LAA LGY C ++N + + +N+ GY+ A + II L++GA N G AL IA +G+ ++ L
Sbjct: 543 FTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDN-QKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 792
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. UniProt/SwissProt
Match: sp|Q7Z020|TRPA1_DROME (Transient receptor potential cation channel subfamily A member 1 OS=Drosophila melanogaster OX=7227 GN=TrpA1 PE=2 SV=4) HSP 1 Score: 196.823 bits (499), Expect = 6.299e-50 Identity = 221/984 (22.46%), Postives = 406/984 (41.26%), Query Frame = 2
Query: 269 HEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQ--DRKGQTPIDLACRLNMIDIVKILLYYG--ANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKL-----CDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIET--IELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAV--QSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKN-TMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAK------------YRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMN------------------------------SIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDP---MCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIV-------NRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXM---VGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
H+AA +L +I + + N K G+T L +AV+S + + + + +D + K Q P+ LA LN + ++++ Y + + G LH +H E ++L+ P NNG PI AA + + Q +I+ D EG +A+ + CLK GA I+ Q++ +H+A G +I+ + + + ++ D + LH + L+ A +N ++ +PLL +A S+ G + ++L A + +KD + +LH +I +G T E + + + + LLN D G PLH A + + LI GA + L N N P+H A R G V+ L+D I D A + L + Q GH + + L + +H +D TG N L A G ++L+ +L + +T LH A + + L+S+G ++ N + + A+ ++ A + N M R +I + + ++ + + KY F L P+ A ++ + E +T A + + +L+ HPLS L KW +G +F + +L+ + +L F T M I DN T ++ ++ ++TMN ++ ++ L + E ++ QKL Y N + ++Y SA+ P + TI +S +IA+ L W ++ +LQ GI ++MF ++ ++IK++++F L+I + +AFYI+ N F N S + + M++GELD+V +++ ++ + + + S+ + + I LM +G+AVGDI+ + +A++ +Q+ +E E LP
Sbjct: 95 HQAAARNRVNILRYIRDQNGDFNAKDNAGNTPLHIAVESDAYDALDYLL---SIPVDTGVLNEKKQAPVHLATELNKVKSLRVMGQYRNVIDIQQGGEHGRTALHLAAIYDHEECARILITEFDACPRKPCNNGYYPIHEAAKNASSKTMEVFFQWGEQRGCTREEMISFYDSEGNVPLHSAVHGGDIKAVELCLKSGAKISTQQHDLSTPVHLACAQGAIDIVKLMFEMQPMEKRLCLSCTDVQKMTPLHCASMFDHPDIVSYLVAEGADINALDKEHRSPLLLAA---SRSGWKTVHLLIRLG----ACISVKDAAARNVLHFVIMNGGRLTDFAEQVANCQTQAQLKLLLNEKDSMGCSPLHYASRDGHIRSLENLIRLGACINLKNNNNESPLHFAARYGRYNTVRQLLDSEKGSFIINESDGAGMTPLHISSQQGHTRVVQLLLNRGALLH-RDHTGRNPLQLAAMSGYTETIELLHSVHSHLLDQVDKDGNTALHLATMENKPHAISVLMSMGCKLVYNVLDMSAIDYAIYYKYPEAALAMVTHEERANEVMALRSDKHPCVTLALIASMPKVFEAVQDKCITKANCKKDSKSFYIKYSFAFLQC-PFMFAKIDEKTGESITTASPIPLPALNTMVTHGRVELLAHPLSQKYLQMKWNSYGKYFHLANLLIYSIFLVFVTIYSSLMMNNIELKAG--------DNKTMSQYCNMGWEQLTMNLSQNPSVASQIRLDSCEERINRTTAILFCAVVIVVYILLNSMRELIQIYQQKLHYILETVNLISWVLYISALVMVTPAFQPDGGINTIHYSAASIAVFLSWFRLLLFLQRFDQVGIYVVMFLEILQTLIKVLMVFSILIIAFGLAFYILLSKIIDPQPNHLSFSNIPMSLLRTFSMMLGELDFVGTYVNTYYRDQLKVPMTSFLILSVFMILMPILLMNLLIGLAVGDIESVRRNAQLKRLAMQVVLHTELERKLP 1058
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. UniProt/SwissProt
Match: sp|O75762|TRPA1_HUMAN (Transient receptor potential cation channel subfamily A member 1 OS=Homo sapiens OX=9606 GN=TRPA1 PE=1 SV=3) HSP 1 Score: 187.963 bits (476), Expect = 3.263e-47 Identity = 226/962 (23.49%), Postives = 413/962 (42.93%), Query Frame = 2
Query: 329 NINK----KSCKGSTALLL--AVKSGNAECVRLICKQKGMEI-DGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLL-HAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNS---------KINIASVINSTDC----------EGYSC-----FLN---------AIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSL----SVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMR-NHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEF---RFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSAS-------VNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIM-----SMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAK--VKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFK---IFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
N NK K C L A G E + I + +E+ D G TP+ A N I+ VK LL GANP ++ M LH ++ + E++K+LL H ++ NG + + +A + EA + ++ I+ A+ S +C GYS F+N A++ +I CL GA I+ + A+H A+ G +EI+ + + + N D +H SL +A+ L+ A +N + +PL+ + S + LLL+ A V +KD + LHL + + L + ++ ++ + L+ D++G PLH AC N L+ ++ + ++ P+H A G + + L+ +I + NE + + + LA ++GH + + L K + D G L +A G +K+IL + R + +T LH AA+ G K V LLS A++ N + L LAL N+ + W ++ K + +I + LL+ + ++ S +Y+F L P + + T + + + +L+ HP+ LL KW +G M +L ++ L T ++ + P +A +++ G + S +++ T+S + ++ S+FG+ + E+ + QK YF SN + ++Y++ I F V+ P +QW G IA+ W N + YLQ N GI I+M + ++ ++++ ++F+ L++ + ++FYI+ Q PF + S + + M++G+++Y FL+P + + + F+I + I L+NL++G+AVGDI + A + +Q+ + E LP
Sbjct: 49 NFNKQKKLKRCDDMDTFFLHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLKKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILAT-------ASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPY-GLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQ-DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL-LKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEVVLTIIRSKRWDECLKIFSHNSPGNKCPITEMIEYLPECMKVLLDFCMLHSTEDKSCRDYYIEYNFKYLQC-PLEFTKKTPTQDVIYEPLTALNAMVQNNRIELLNHPVCKEYLLMKWLAYGFRAHMMNLGSYCLGLIPMTILVVNIKPGMA----FNSTGIINETSDHSEILDTTNSYLIKTCMILVFLSSIFGYCK---EAGQIFQQKRNYFMDISNVLEWIIYTTGIIFVLPLFVEIP-AHLQWQCGAIAVYFYWMNFLLYLQRFENCGIFIVMLEVILKTLLRSTVVFIFLLLAFGLSFYILLNLQDPFSSPLLSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTSLEKKLP 991 HSP 2 Score: 105.531 bits (262), Expect = 1.321e-21 Identity = 115/475 (24.21%), Postives = 194/475 (40.84%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDG-----------------------------------------MCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHL------GIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGH 1549
LH A E ++F+LS+ N N ++ L +AV+ N E ++++ + + ++++ + G T + +AC N + ++ILL GA P KS G LH +++ LEMIK+ L + + + I AA+ G E L I S S ++N+TD + A + + + GADIN +EG++ L +A+ I+ L G ++ DN + LHL G+ N + + ++ N TPL + V L F N + K K K++ LH + G I T + L Q I + LLN D +G PLH+A N K+ L+ +GA L L ++N +H A+ G+ + +K ++D N++ +ED + A + GH
Sbjct: 102 LHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLKKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGS----VDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILATASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDG-CTPLHYACRQGGPGSVNNLLGF-------NVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTR---LLNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGH 560 HSP 3 Score: 69.3218 bits (168), Expect = 1.756e-10 Identity = 66/277 (23.83%), Postives = 124/277 (44.77%), Query Frame = 2
Query: 263 LLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACR------------LNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN-INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHV 1054
+LH A++ + EL ++++S +INK +G + L+LA S + V L+ KG ++D +D G+ + L + + M I +++ M + DG LH+ R + LL S K + SP+ AAS G + +Q + ++++ +N D G + A + ++ LK GA + L+ + G ALH AS G+++ + + D + + +D + ++ALH G LL ++A +
Sbjct: 312 MLHRASLFDHHELADYLISVGADINKIDSEGRSPLILATASASWNIVNLLL-SKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELV-------MDEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRL-----LNEGDLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADI 574
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. UniProt/SwissProt
Match: sp|Q8BLA8|TRPA1_MOUSE (Transient receptor potential cation channel subfamily A member 1 OS=Mus musculus OX=10090 GN=Trpa1 PE=1 SV=1) HSP 1 Score: 187.578 bits (475), Expect = 5.025e-47 Identity = 229/970 (23.61%), Postives = 421/970 (43.40%), Query Frame = 2
Query: 224 QYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCK--------GSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYD-GMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN----INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGH----IETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMR-NHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHF---FMLDAGPYD----SASVNSRYTEFMTI----AKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGC--PVDNSTDNKLKSLTDSEITMNSIM----SMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKV-KDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFK---IFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
+Y DEN LH AA EL+E I IN SC+ G+T L A + E V+ + Q G + ++R +P+ +A +++K+L + A + E + G L ++ E +++LL + G P+ AA G + L + + + + IN + + S A++ +I CL GA I++ +N ALH A+ G ++I+ + + +N+VD N ++ LH +AE L+ A +N + +PL+ + S + LLL A V +KD + LHL + + + + Q IKE L+ D++G PLH AC + N L+ ++ + ++ P+H A G + + L+ +I + NE + + + LA ++GH + + L K + D G L +A G +K+IL + R + +T LH AA+ G K V LLS A++ N + L +AL N+ + + W ++ F IM+ + E + L+ ++ +KS YH F P A E +TI ++ + +L+ HP+ LL KW +G M +L ++ L T ++ P +A +++ G ++ + ++ +L I + I+ S+FG+ + E ++ QK YF +N + ++Y+++I F + + +QW G IAI W N + YLQ N GI I+M + + ++++ +F+ L++ + ++FY++ Q F S + + M++G+++Y FL+P F+ + + + F++ + I L+NL++G+AVGDI + A + +Q+ + E LP
Sbjct: 59 KYEDEN-----LCPLHHAAAEGQVELMELI------INGSSCEVLNIMDGYGNTPLHCAAEKNQVESVKFLLSQ-GANPNLRNRNMMSPLHIAVHGMYNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKKCMELILAYGEKNGYSRETHINFVNHKKASPLHLAVQSGDLDMIKMCLDNGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVDGNQETLLHRASLFDHHDLAEYLISVGADINSTDSEGRSPLILAT-------ASASWNIVNLLLCKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFMQMQHIKE-----LVMDEDNDGCTPLHYACRQGVPVSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQ-DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL-LKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTIRNKRWDECLQV-FTHNSPSNRCPIMEMVEYLPECMKVLLDFCMIPSTEDKSCQDYHIEYNFKYLQCPLSMTKKVAPTQDVVYEPLTILNVMVQHNRIELLNHPVCREYLLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMA----FNSTGIINGTSSTHEERIDTLNSFPIKICMILVFLSSIFGYCK---EVIQIFQQKRNYFLDYNNALEWVIYTTSIIFVLPLFLNIPAYMQWQCGAIAIFFYWMNFLLYLQRFENCGIFIVMLEVIFKTLLRSTGVFIFLLLAFGLSFYVLLNFQDAFSTPLLSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTNLEKKLP 994
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. UniProt/SwissProt
Match: sp|Q6RI86|TRPA1_RAT (Transient receptor potential cation channel subfamily A member 1 OS=Rattus norvegicus OX=10116 GN=Trpa1 PE=2 SV=1) HSP 1 Score: 186.037 bits (471), Expect = 1.589e-46 Identity = 233/970 (24.02%), Postives = 419/970 (43.20%), Query Frame = 2
Query: 224 QYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCK--------GSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYD-GMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGIN----INSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGH----IETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMR-NHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHF---FMLDAGPYDSASVNSRYT-------EFMTI----AKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIA-DSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIM--SMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKV-KDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFK---IFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
+Y DEN LLH AA EL++ I IN SC+ G+T L A + E V+ + Q G + ++R P+ +A + +++K+L + A + E + G L ++ E +++LL + G P+ AA G L + + + + IN + + S A++ +I CL GA I++ +N ALH A+ G ++I+ + + +N+VD N ++ LH +A+ L+ A +N + +PL+ + S + LLL+ A V +KD + LHL + + + L Q IKE L+ D++G PLH AC N L+ ++ + ++ P+H A G + + L+ +I + NE + + + LA ++GH + + L K + D G L +A G +K+IL + R + +T LH AA+ G K V LLS A++ N + L +AL N+ + W ++ F IM+ + E + L+ ++ +KS YH F P S+ + T E +TI ++ + +L+ HP+ LL KW +G M +L ++ L T ++ P +A +S N+ N L S +I M + S+FG+ + E ++ QK YF +N + ++Y++++ F + D +QW G IAI W N + YLQ N GI I+M + + ++++ +F+ L++ + ++FY++ Q F S + + M++G+++Y FL+P F+ + + + F++ + I L+NL++G+AVGDI + A + +Q+ + E LP
Sbjct: 59 KYEDEN-----LCLLHHAAAEGQVELMQLI------INGSSCEALNVMDDYGNTPLHWAAEKNQVESVKFLLSQ-GANPNLRNRNMMAPLHIAVQGMYNEVIKVLTEHKATNINLEGENGNTALMSTCAKDNSEALQILLEKGAKLCKSNKWGDYPVHQAAFSGAKRCMELILAYGEKTGYSREAHINFVNHKKASPLHLAVQSGDLDMIKMCLDSGAHIDMMENAKCMALHFAATQGATDIVKLMISSYTGSSDIVNAVDGNQETLLHRASLFDHHDLADYLISVGADINSTDSEGRSPLILAT-------ASASWNIVNLLLSKGAKVDIKDHLGRNFLHLTVQQPYGLRNLRPEFLQMQHIKE-----LVMDEDNDGCTPLHYACRQGAPVSVNNLLRFNVSVHSKSKDKKSPLHFAASYGRINTCQRLLQ-DISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL-LKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDRLDEEGNTALHFAAREGHAKAVAMLLSYNADILLNKKQASFLHIALHNKRKEVVLTTIRSKRWDECLQV-FTHDSPSNRCPIMEMVEYLPECMKVLLDFCMIPSTEDKSCQDYHIEYNFKYLQCPL---SMTKKVTPTQDVIYEPLTILNVMVQHNRIELLNHPVCREYLLMKWCAYGFRAHMMNLGSYCLGLIPMTLLVVKIQPGMAFNSTGIINETISTHEERINTLNSFP-LKICMILVFLSSIFGYCK---EVVQIFQQKRNYFLDYNNALEWVIYTTSMIFVLPLFLDIPAYMQWQCGAIAIFFYWMNFLLYLQRFENCGIFIVMLEVIFKTLLRSTGVFIFLLLAFGLSFYVLLNFQDAFSTPLLSLIQTFSMMLGDINYRDAFLEPLFRNELAYPVLTFGQLIAFTMFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHTNLEKKLP 994
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. UniProt/SwissProt
Match: sp|Q18297|TRPA1_CAEEL (Transient receptor potential cation channel subfamily A member 1 homolog OS=Caenorhabditis elegans OX=6239 GN=trpa-1 PE=2 SV=5) HSP 1 Score: 182.185 bits (461), Expect = 2.315e-45 Identity = 232/1106 (20.98%), Postives = 454/1106 (41.05%), Query Frame = 2
Query: 248 NNTFNLLHEAAISKNPELLEFILSKKP-NINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRL--NMIDIVKILLYYGANPMK-----------------SEYD-----GMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIA-------SVINSTDCEGYSCFL---------------NAIRYKQRTIILECLKYGADINLA---QNEGKNA----------LHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHA-HVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLF-----------------------QLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEM-YENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTM---------EFRFKTG---KTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLD--------------------AGPYD-----SASVNSRYTEFMTIAKYRKEKLIL---------HPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIA--------DSPDYD-NQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCT------IQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYF----LDPGFKIF----TAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQ-----AKFYEPVFVYKQMRRSVFQRFFS 3088
+N +++H++A N L+ L K P +N + T L A + GN + V+L+ + + + ++R+G TP+ +A + DI I+ A+ + +E D + LH+ ++ + L+ K + +D+N ++P+ LA G E IQ L+ + N+ +V + G +L N +++T + ++ L Q E KN+ +H A+E G+ E++ L + G N N ++ LH+ L V L+ +++V + LTPL+ + S+ VE +A A++ + DK ++T + + + ++E + +++ E+ ++ ++N D + + P+H+ SN ++ L GA++ N +E +H A G V+ L++ +I+ + +++E + + LA +SGH + L + +K+ L A G + + ++ K ++ + T LH AA G +V Y ++ G + + +T +A +N H + A+ FL + WKN M + R +T ++ K ++A+ +++ +E + +S+ Y+F LD YD S + + + KY KL+ HPLS LL KW R G + L +L ++ T + H P DS +D N+ CP N+ T ++ I+ +++ E + +K Y N++ +YS+A+ + T QW + I W N++F ++ +P FGI ++MF ++V + + +F+ +I ++ +FY++ +N+ F + S K M+IGE ++ F K+F TA+ L F I+++I L+NL+VG+AV DI + A++ +Q+ + + E+ L +Q A F Y ++ ++ F ++S
Sbjct: 48 DNLRSIIHQSAREGNVNALQEALLKAPLAVNAQDGDFMTPLHYAARYGNYDAVKLLLSKNALP-NTKNREGDTPLHIASKYIYGYSDICSIIDEDQADSARKYNTATKKIINALVSENAEIDPVNKYQLTPLHYAAMKSNFSALHALIKLKADVDAEDDNKMTPLLLACVHGSQE----IIQELIKANSNVTKRDQRLNTVFHIVALRGEPEYLEMMMDHDPVEAIKALNLFNNEKKTPLRMAVEGNHPETLKKILQMEKKNSCKWMDREKELIHFAAEKGFLEVLKALVEAGGNKNELNEVKAVPLHVAAQMNQLEVVSYLIEEEKDNIDVVDEQGLTPLMMAVTHDSKKCVEYLIA-------KKANLTITDKDERTPVFIGAKFNALSSVEYILDHLRKKNKETERSALKSPTRNTLRIVSEDVRRTMVNMVDRDQNTPMHIVASNGYLEMMQLLQKHGASITQVNEDEETALHRAAIGGQTGAVRQLLEWDIRLLLMKDEMGNSALHLAARSGHDATTKVLLDNGADKEAKNSYQKTPLQVAVDSGKLETCQRLVAKGAQIE-SSSDTKTVLHTAAFYGNESIVRYFIAEGVTIDRRDEEGKTAFDIACENDHKDVARAFLETDQWKNLMIPCDVIPLDKHRNPVNMKRRTPFRTLLTKFPELASFVMDNCIEKSKEETDSTQSVA-YNFEFLDDTYMMRCVSDDGTGEQLIGCKSAYDEDFKLEKDAQSYASNYDRVYKYHPLKLMADAEKLHLLNHPLSKALLKYKWNRLGRPMYYFALFMYLVFIVSLTQYVRHTKAPYNVWNEESYYDSEYFDENETCPQINT--------TKPDVVWKIIIQTLAVCQILVECFQLFQRKFAYLVNWENWIDCFIYSTALITVYDFSECSATSGVRQNWQWILAALCIFFGWINLLFMIRKMPRFGIFVVMFVDIVKTFFRFFPVFVLFIIAFSSSFYVILQNRPEFSTIFMSPLKTTVMMIGEFEFTGIFHGDETTHAEKMFGPAHTAVACALFFFFCIIMTILLMNLLVGLAVDDIKGVQEKAELKRLAMQVDLVLQIEASLHFFIQRTKKYATCRYATFPYGKLHKTGFAGWWS 1131
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. TrEMBL
Match: A0A267FPG6 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig025935g2 PE=3 SV=1) HSP 1 Score: 362.459 bits (929), Expect = 1.238e-103 Identity = 265/939 (28.22%), Postives = 462/939 (49.20%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKE--EEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLID----LNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAA--QAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKS-LTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMP-PIADSPDYDNQ-GC---PVDNSTDNKLKSLTDSEITMNSIMSMFGFL--RLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYE 3034
LH A S ++ ++ N+N K +GS L +A ++ + + + +D D +GQT + +ACR N ++V+ILL + ANP E DG LH P R N+L++ ++L + +D +G++P+ +AAS E + S NI ++N D EG S A R + ++I GADIN+ E LH AS +G E + KL + G + N D + LH + + LL + + +TP + +Q+ LA L + D++++ T LH + +G IE + L E E + +LN+ D YP+H A ++ L+S GA+ + + P+ A + G +E+V+++ + L Q + R+ +++A + GH +FE+L + + KDE G LM + G + +++ K ++ + ++T LH A + VE LL GA++ +N +TP+ +A+ N + ++F +D + M +R + G TH+ +I + A +LN+ + S + ++K+ + Y+F LD GP D AS + RY T+ K R+ +L+ HP+ L+ +KW FFW DL+ + +L T + P P+ + D Q GC D + + LT+ + + + + G L RL+ E++K ++LQYFK N+ +++Y F C W G ++I+ W ++F + +P GI LMF+ V+ S++K++++F +IG+A+AF I QTPF+ +S K +DM +GELD+V+YF+ + L++ +F I++ I L+NL+VGIAVGDID + +A + + ++IT E E+ LPR Q + +
Sbjct: 178 LHYAVKSDRVGVVAALIQAGANVNMKGREGSRPLHVAANFNQIGALKELLSSRKVRVDATDDRGQTALHVACRRNHEEVVQILLGHKANPQLKELDGTSVLHLPSRRNNLQLCQILTNDTALISCRDKHGVTPLMVAASESGEELLSHFVSVCKLSDKNIVQMLNIKDAEGNSAMHYAARSDKPSMIQGLKNCGADINIRNLENSTPLHAASALGHKESVIKLLELGADPNQQDKLGRTPLHSCAISKQEEICGILLKAGSDPQAADAEFMTPFHWACRR-NQLNEAAHLADADLDVIAATDIQMR-----TGLHWAVLAGSIELVNYLLDKAAELPEGCETVLNASDAQDKYPVHYAVEVGNTELLVALLSRGADFHVVDMEGRTPVQLAVKMGCIELVQNIFEHSEKLKHQALKHRDMSGMTSLLIAAEQGHSELFEYLLEQGADFMVKDEIGRTALMLSVGSGHHEIASVMIDKGVDVNASDSSRNTALHYACKHEDSDASCVELLLKNGAQLQQNYNGETPVDVAVLNNNNPAIQLFFSDAHRTWVMTYRKENGYTHLDVLIQHSPQTAELILNQAM-TESGADHMDKNFMVVYNFTDLDPGPDDPASAHRRYLALRTMVKRRRVELLEHPVCQALIESKWAVARYFFWF-DLLCYAVFLCCLTAFVADNGPLPLWE---IDTQTGCRNYTTDGVSSGTRQKLTNPTLILEKAI-VIGILSIRLVIETVKVAFKRLQYFKNYENFFFIVLYIFTFIFVYPPDSEPCQYNWICGMFSVIMAWCLLIFQFEHLPKIGIYSLMFQQVIVSLVKVLVIFSFCIIGFALAFNIGMVAQTPFKYITYSILKTFDMTVGELDFVTYFISNSYGGMQTGLLVVFVIFVIIMPIGLMNLLVGIAVGDIDGISKEASLKLIDIRITLFYELETNLPRYFQRRLHR 1104
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. TrEMBL
Match: A0A267E899 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig025935g1 PE=3 SV=1) HSP 1 Score: 360.533 bits (924), Expect = 5.725e-103 Identity = 264/939 (28.12%), Postives = 461/939 (49.09%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKE--EEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLID----LNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAA--QAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKS-LTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMP-PIADSPDYDNQ-GC---PVDNSTDNKLKSLTDSEITMNSIMSMFGFL--RLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYE 3034
LH A S ++ ++ N+N K +GS L +A ++ + + + +D D +GQT + +ACR N ++V+ILL + ANP E DG LH P R N+L++ ++L + +D +G++P+ +AAS E + S NI ++N D EG S A R + ++I GADIN+ E LH AS +G E + KL + G + N D + LH + + LL + + +TP + +Q+ LA L + D++++ T LH + +G IE + L E E + +LN+ D YP+H A ++ L+S GA+ + + P+ A + G +E+V+ + + L Q + R+ +++A + GH +F++L + + KDE G LM + G + +++ K ++ + ++T LH A + VE LL GA++ +N +TP+ +A+ N + ++F +D + M +R + G TH+ +I + A +LN+ + S + ++K+ + Y+F LD GP D AS + RY T+ K R+ +L+ HP+ L+ +KW FFW DL+ + +L T + P P+ + D Q GC D + + LT+ + + + + G L RL+ E++K ++LQYFK N+ +++Y F C W G ++I+ W ++F + +P GI LMF+ V+ S++K++++F +IG+A+AF I QTPF+ +S K +DM +GELD+V+YF+ + L++ +F I++ I L+NL+VGIAVGDID + +A + + ++IT E E+ LPR Q + +
Sbjct: 178 LHYAVKSDRVGVVAALIQAGANVNMKGREGSRPLHVAANFNQIGALKELLSSRKVRVDATDDRGQTALHVACRRNHEEVVQILLGHKANPQLKELDGTSVLHLPSRRNNLQLCQILTNDTALISCRDKHGVTPLMVAASESGEELLSHFVSVCKLSDKNIVQMLNIKDAEGNSAMHYAARSDKPSMIQGLKNCGADINIRNLENSTPLHAASALGHKESVMKLLELGADPNQQDKLGRTPLHSCAISKQEEICGILLKAGSDPQAADAEFMTPFHWACRR-NQLNEAAHLADADLDVIAATDIQMR-----TGLHWAVLAGSIELVNYLLDKAAELPEGCETVLNASDAQDKYPVHYAVEVGNTELLVALLSRGADFHVVDMEGRTPVQLAVKMGCIELVQKIFEHSEKLKHQALKHRDMSGMTSLLIAAEQGHSELFDYLLEQGADFMVKDEIGRTALMLSVGSGHHEIASVMIDKGVDVNASDSSRNTALHYACKHEDSDASCVELLLKNGAQLQQNYNGETPVDVAVLNNNNPAIQLFFSDAHRNWVMTYRKENGYTHLDVLIQHSPQTAELILNQAM-TESGADHMDKNFMVVYNFTDLDPGPDDPASAHRRYLALRTMVKRRRVELLEHPVCQALIESKWAVARYFFWF-DLLCYAVFLCCLTAFVADNGPLPLWE---IDTQTGCRNYTTDGVSSGTRQKLTNPTLILEKAI-VIGILSIRLVIETVKVAFKRLQYFKNYENFFFIVLYIFTFIFVYPPDSEPCQYNWICGMFSVIMAWCLLIFQFEHLPKIGIYSLMFQQVIVSLVKVLVIFSFCIIGFALAFNIGMVAQTPFKYITYSILKTFDMTVGELDFVTYFISNSYGGMQTGLLVVFVIFVIIMPIGLMNLLVGIAVGDIDGISKEASLKLIDIRITLFYELETNLPRYFQRRLHR 1104
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. TrEMBL
Match: A0A267G9R9 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000210g4 PE=3 SV=1) HSP 1 Score: 348.591 bits (893), Expect = 2.812e-99 Identity = 263/936 (28.10%), Postives = 461/936 (49.25%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIAS-VINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLN--IQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQ-AGQT-KMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMP-PIA--DSPDYDNQGCPVDNST--DNKLKSLTDSEITMN-SIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYE 3034
LH A +++ ++ N+N K +GS + +A ++ +R I K + +D D +GQT + +ACR N VKILL + AN E DG LH P R N+LE+ ++L KD G++P+ +AA+ G + I + A +++ D EG S A + + I ++G +++L E +H+A+ +G E + KL G N D N + LH I L + + LL+ A + + +TPL + + G+ + A +LL + + L D +T LH + + ++ +ELL + ++ N+ D + YP+H A N ++ L++ GA+ + A + GH +V+D+ L I++ +R+ D + +++A + GH + FL + + +KDE G LM +C G +V ++ K ++ + +++T LH A + AG + + +E LLS GA++ +N +TP+ +A+ N + + +D M +R TG +HM +I + A +LNR + N + ++FF LD GP D AS +RY T+ + ++E L+ HPL LL KW FFW D + +L T + P PI+ D+ N GC +S+ + + LT+ + + S++ F +RL+ E +K + ++LQY K N + +Y F C W FG ++IL W ++F + +P GI LMF+ V+ S++K++L+F +IG+ +AF I +QTPF+ +S K +DM +GE+++V+YF+ L++ +F +++ I L+NL+VGIAVGDI+ + +A + + ++I + E E+ LPR Q + Y
Sbjct: 94 LHYAVKCNRVDMVSLLMQAGANVNIKGREGSRPIHVAANFNQSDALREILKSRRTRVDATDDRGQTALHVACRRNHEPSVKILLSHKANSQLKELDGTSVLHLPSRRNNLELCQMLTTDTGLITCKDKYGVTPLMVAAAEGSEDLLNYFISVCKKTTHGAAGRILDMQDSEGNSSVHFAAKNDKFLAIEILSEHGVNLDLQNLEQSAPIHLAATLGHRESVAKLIHLGALPNLSDKNGRTPLHCCIIARQLEICDTLLLAGAQSRAADEDFMTPL----HWACRRGLTQ--AARRLLRVDPGCLSLVDIHMRTGLHWAVLACAVDLVELLLAQAGDSDES--ANASDFHDKYPVHYAVEMNDSQLVRILLTHGADFHAVDTEGRTATQLAVKLGHEGLVRDICGLGQYIKRQALRHRDLRGVTSLLIAAEHGHTRVLHFLLEQGADFTAKDEFGRTALMLSCGGGHSDIVATMIDKGVDVNASDANRNTALHYACKHAGSSARSLELLLSNGAQLQQNYNGETPVDVAVLNNNGPAISLLFSDAYCDWVMSYRKDTGMSHMDILIQHSPQTALTILNRSMTKSRADNFEKNFMVTHNFFYLDPGPDDPASKPNRYLGLRTMVERQREDLLKHPLCAALLEYKWSFTRYFFW-CDFFFYAVFLCCLTAFVADQGPLPISLVDA----NTGCRNTSSSGGSGQRQKLTNGRLILEKSVVIGFLCVRLVLEFIKLVFKRLQYLKNYENLFFVTLYILTFVFIYPPDSEPCIDNWIFGIFSVILAWCLLIFQFEHLPVTGIYSLMFQKVIISLVKVLLIFAFFIIGFGLAFNIGLVSQTPFKYPMYSILKTFDMTVGEMEFVTYFISGTSGRMQLALLVVFVIFVVVMPIGLMNLLVGIAVGDIEGISKEAGLRLVEIRINLVYEMETNLPRYFQRRLYR 1016
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. TrEMBL
Match: A0A267H4S2 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000210g3 PE=3 SV=1) HSP 1 Score: 346.665 bits (888), Expect = 1.263e-98 Identity = 262/936 (27.99%), Postives = 461/936 (49.25%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIAS-VINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLN--IQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQ-AGQT-KMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMP-PIA--DSPDYDNQGCPVDNST--DNKLKSLTDSEITMN-SIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYE 3034
LH A +++ ++ N+N K +GS + +A ++ +R + + +D D +GQT + +ACR N VKILL + AN E DG LH P R N+LE+ ++L KD G++P+ +AA+ G + I + A +++ D EG S A + + I ++GA+++L E +H+A+ +G E + KL G N D N + LH I L + + LL+ A + + +TPL + + G+ + A +LL + + L D +T LH + + ++ +ELL + ++ N+ D + YP+H A N ++ L++ GA+ + A + GH +V+D+ L I++ +R+ D + +++A + GH + FL + + +KDE G LM +C G +V ++ K ++ + +++T LH A + AG + + +E LLS GA++ +N +TP+ +A+ N + + +D M +R TG +HM +I + A +LNR + N + ++FF LD GP D AS +RY T+ + ++E L+ HPL LL KW FFW D + +L T + P PI+ D+ N GC +S+ + + LT+ + + S++ F +RL+ E +K + ++LQY K N + +Y F C W FG ++IL W ++F + +P GI LMF+ V+ S++K++L+F +IG+ +AF I +QTPF+ +S K +DM +GE+++V+YF+ L++ +F +++ I L+NL+VGIAVGDI+ + +A + + ++I + E E+ LPR Q + Y
Sbjct: 94 LHYAVKCNRVDMVSLLMQAGANVNIKGREGSRPIHVAANFNQSDALRELLNSRRTRVDATDDRGQTALHVACRRNHEPSVKILLSHKANSQLKELDGTSVLHLPSRRNNLELCQMLTTDTGLITCKDKYGVTPLMVAAAEGSEDLLNYFISVCKKTTHGAAGRILDMQDSEGNSSVHFAAKNDKFLAIEILSEHGANLDLQNLEQSAPIHLAATLGHRESVAKLIHLGALPNLSDKNGRTPLHCCIIARQLEICDTLLLAGAQSRAADEDFMTPL----HWACRRGLTQ--AARRLLRVDPGCLSLVDIHMRTGLHWAVLACAVDLVELLLAQAGDSDES--ANASDFHDKYPVHYAVEMNDSQLVRILLTHGADFHAVDTEGRTATQLAVKLGHEGLVRDICGLGQYIKRQALRHRDLRGVTSLLIAAEHGHTRVLHFLLEQGADFTAKDEFGRTALMLSCGGGHSDIVATMIDKGVDVNASDVNRNTALHYACKHAGSSARSLELLLSNGAQLQQNYNGETPVDVAVLNNNGPAISLLFSDAYCDWVMSYRKDTGMSHMDILIQHSPQTALTILNRSMTKSGADNLEKNFMVTHNFFYLDPGPDDPASKPNRYLGLRTMVERQREDLLKHPLCAALLEYKWSFTRYFFW-CDFFFYAVFLCCLTAFVADQGPLPISLVDA----NTGCRNTSSSGGSGQRQKLTNGRLILEKSVVIGFLCVRLVLEFIKLVFKRLQYLKNYENLFFVTLYILTFVFIYPPDSEPCIDNWIFGIFSVILAWCLLIFQFEHLPVTGIYSLMFQKVIISLVKVLLIFAFFIIGFGLAFNIGLVSQTPFKYPMYSILKTFDMTVGEMEFVTYFISGTSGRMQLALLVVFVIFVVVMPIGLMNLLVGIAVGDIEGISKEAGLRLVEIRINLVYEMETNLPRYFQRRLYR 1016
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. TrEMBL
Match: A0A267EGL5 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000210g1 PE=3 SV=1) HSP 1 Score: 345.895 bits (886), Expect = 2.897e-98 Identity = 261/936 (27.88%), Postives = 460/936 (49.15%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIAS-VINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLN--IQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQ-AGQT-KMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMP-PIA--DSPDYDNQGCPVDNST--DNKLKSLTDSEITMN-SIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYE 3034
LH A +++ ++ N+N K +GS + +A ++ +R + + +D D +GQT + +ACR N VKILL + AN E DG LH P R N+LE+ ++L KD G++P+ +AA+ G + I + A +++ D EG S A + + I ++G +++L E +H+A+ +G E + KL G N D N + LH I L + + LL+ A + + +TPL + + G+ + A +LL + + L D +T LH + + ++ +ELL + ++ N+ D + YP+H A N ++ L++ GA+ + A + GH +V+D+ L I++ +R+ D + +++A + GH + FL + + +KDE G LM +C G +V ++ K ++ + +++T LH A + AG + + +E LLS GA++ +N +TP+ +A+ N + + +D M +R TG +HM +I + A +LNR + N + ++FF LD GP D AS +RY T+ + ++E L+ HPL LL KW FFW D + +L T + P PI+ D+ N GC +S+ + + LT+ + + S++ F +RL+ E +K + ++LQY K N + +Y F C W FG ++IL W ++F + +P GI LMF+ V+ S++K++L+F +IG+ +AF I +QTPF+ +S K +DM +GE+++V+YF+ L++ +F +++ I L+NL+VGIAVGDI+ + +A + + ++I + E E+ LPR Q + Y
Sbjct: 94 LHYAVKCNRVDMVSLLMQAGANVNIKGREGSRPIHVAANFNQSDALRELLNSRRTRVDATDDRGQTALHVACRRNHEPSVKILLSHKANSQLKELDGTSVLHLPSRRNNLELCQMLTTDTGLITCKDKYGVTPLMVAAAEGSEDLLNYFISVCKKTTHGAAGRILDMQDSEGNSSVHFAAKNDKFLAIEILSEHGVNLDLQNLEQSAPIHLAATLGHRESVAKLIHLGALPNLSDKNGRTPLHCCIIARQLEICDTLLLAGAQSRAADEDFMTPL----HWACRRGLTQ--AARRLLRVDPGCLSLVDIHMRTGLHWAVLACAVDLVELLLAQAGDSDES--ANASDFHDKYPVHYAVEMNDSQLVRILLTHGADFHAVDTEGRTATQLAVKLGHEGLVRDICGLGQYIKRQALRHRDLRGVTSLLIAAEHGHTRVLHFLLEQGADFTAKDEFGRTALMLSCGGGHSDIVATMIDKGVDVNASDANRNTALHYACKHAGSSARSLELLLSNGAQLQQNYNGETPVDVAVLNNNGPAISLLFSDAYCDWVMSYRKDTGMSHMDILIQHSPQTALTILNRSMTKSGADNFEKNFMVTHNFFYLDPGPDDPASKPNRYLGLRTMVERQREDLLKHPLCAALLEYKWSFTRYFFW-CDFFFYAVFLCCLTAFVADQGPLPISLVDA----NTGCRNTSSSGGSGQRQKLTNGRLILEKSVVIGFLCVRLVLEFIKLVFKRLQYLKNYENLFFVTLYILTFVFIYPPDSEPCIDNWIFGIFSVILAWCLLIFQFEHLPVTGIYSLMFQKVIISLVKVLLIFAFFIIGFGLAFNIGLVSQTPFKYPMYSILKTFDMTVGEMEFVTYFISGTSGRMQLALLVVFVIFVVVMPIGLMNLLVGIAVGDIEGISKEAGLRLVEIRINLVYEMETNLPRYFQRRLYR 1016
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Cavefish
Match: trpa1b (transient receptor potential cation channel subfamily A member 1 [Source:NCBI gene;Acc:103042231]) HSP 1 Score: 186.037 bits (471), Expect = 1.414e-47 Identity = 246/980 (25.10%), Postives = 412/980 (42.04%), Query Frame = 2
Query: 272 EAAISKNPELLEFILSKKPNI--NKKSCKGSTALLLAVKSGNAECVRLICKQKG-MEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAAS----------------------LGYL-----------EAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSL----SVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI--ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE---DIANELLNRGL-EVISDTNSVNKSLTKYHFFMLDA-------GPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDN-QGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNY------VVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDP---GFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
E + N LEF+ K P + ++ C G+ + A S N +RLI G E++ QD G+TP+ A N +LL GA+P LH I H +++LLL + +++ + G +P +A S LG+ EA + +Q I + IN D S A+R +I C+ GA ++ Q + ALH A G +E + + + + N D A +H +L +AE L+ A ++ + L+PLL L + K+++FL L AD ++KDK + LHL+I G E L Q E L++ D G PLH AC + ++S+ L + + +H A G L L++ I + NE E N + LA + GH + E L + S D G + L +A G + ++L + L N +T LH AA+AG V+ LL+ GA N + L A+ N A + + + FK G ++ E + LL+ + E D N++N +T Y+F L A D + + +Y + +L+ HP+ L KW+ +GS + +L +L L T++I + P S + V T + + S+ I M +M+++ + E ++ Q+L YF +N + L++ +FF+ K W G +AI+ W N + Y Q FGI ++MF ++ ++I I+LF+ L++ + ++FY + ++ F + S A+ + M +GEL+Y + L+ G F + + LF +L+ I L+NLM+G+AVGDI + +A + +QI + E LP
Sbjct: 25 EWSCKGNISSLEFLSQKNPELLKSRDEC-GAGPIHHAAASANLAVIRLIVTVVGPEELNTQDDHGRTPLHWAVEKNQEGSCSLLLELGADPNILSLSLTAPLHLAISLEHNNLVQLLLLCDRTDVDLEGDLGNTPAMVACSNNNCQALQILFKYNAKLCHQNKLGHFAIHTVAFAGAKEAMEVILQKGEEMGITTSGHINYLDKSKSSPLHLAVRGGNTEVIKLCISKGAKVDQQQCDKSTALHFACTQGATEAVKIMLQPYERMEEIINIRDGANQTPLHRATLFDHVELAEYLVSKGADIDCIDCKGLSPLL----LATTCSAWKTVSFL---LLKGADFRVKDKAGRNFLHLVIFQPKGLKNLPENLLQSKAVRE---LMSDEDYEGCTPLHYACKLGIHDSVKNMLSQKICLGRKSKQKKSGLHFAAEYGRLNTCIRLLE-TISDSRLLNEGEENGLTPLHLASRGGHTKVVELLLRRGALFQS-DYKGWSCLHHAAAEGYTQTMVILLAANVKLLDYTNEEGNTALHLAARAGHVAAVKLLLNRGALFMLNKNGASFLHEAVRNGKKEVANAAIENERSSEALSL-FKKGPGFRCVVLDLIEFLPESTKHLLDLCMVESEHDPNNINYHIT-YNFKWLQAPILLKKYAKTDKSMNFQPLAALNAMVQYNRLELLTHPVCQKYLEMKWKAYGSKVHLLNLAVYLLGLLPLTYLIINLKPTQNTSVNGTTVTMASVSFRTQSYMISVC---IVMVLVMNVYAICK---ELVQLAQQRLIYFMDSTNVSDWASAISSLVFVIPLFFSVDNK-----WHWEAGALAILFAWINFLLYFQRFERFGIYVVMFGEIIKTLISTIVLFVFLLLAFGLSFYALMLHRVEFNSISLSLAQTFVMTVGELNYQNTLLEAYEQGQLAFPEISYFIFVLFVLLMPILLMNLMIGLAVGDIAEVQRNATLKRIAMQINLHTNLEEKLP 978
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Cavefish
Match: trpa1b (transient receptor potential cation channel subfamily A member 1 [Source:NCBI gene;Acc:103042231]) HSP 1 Score: 186.037 bits (471), Expect = 1.414e-47 Identity = 246/980 (25.10%), Postives = 412/980 (42.04%), Query Frame = 2
Query: 272 EAAISKNPELLEFILSKKPNI--NKKSCKGSTALLLAVKSGNAECVRLICKQKG-MEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAAS----------------------LGYL-----------EAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSL----SVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI--ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE---DIANELLNRGL-EVISDTNSVNKSLTKYHFFMLDA-------GPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDN-QGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNY------VVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDP---GFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
E + N LEF+ K P + ++ C G+ + A S N +RLI G E++ QD G+TP+ A N +LL GA+P LH I H +++LLL + +++ + G +P +A S LG+ EA + +Q I + IN D S A+R +I C+ GA ++ Q + ALH A G +E + + + + N D A +H +L +AE L+ A ++ + L+PLL L + K+++FL L AD ++KDK + LHL+I G E L Q E L++ D G PLH AC + ++S+ L + + +H A G L L++ I + NE E N + LA + GH + E L + S D G + L +A G + ++L + L N +T LH AA+AG V+ LL+ GA N + L A+ N A + + + FK G ++ E + LL+ + E D N++N +T Y+F L A D + + +Y + +L+ HP+ L KW+ +GS + +L +L L T++I + P S + V T + + S+ I M +M+++ + E ++ Q+L YF +N + L++ +FF+ K W G +AI+ W N + Y Q FGI ++MF ++ ++I I+LF+ L++ + ++FY + ++ F + S A+ + M +GEL+Y + L+ G F + + LF +L+ I L+NLM+G+AVGDI + +A + +QI + E LP
Sbjct: 25 EWSCKGNISSLEFLSQKNPELLKSRDEC-GAGPIHHAAASANLAVIRLIVTVVGPEELNTQDDHGRTPLHWAVEKNQEGSCSLLLELGADPNILSLSLTAPLHLAISLEHNNLVQLLLLCDRTDVDLEGDLGNTPAMVACSNNNCQALQILFKYNAKLCHQNKLGHFAIHTVAFAGAKEAMEVILQKGEEMGITTSGHINYLDKSKSSPLHLAVRGGNTEVIKLCISKGAKVDQQQCDKSTALHFACTQGATEAVKIMLQPYERMEEIINIRDGANQTPLHRATLFDHVELAEYLVSKGADIDCIDCKGLSPLL----LATTCSAWKTVSFL---LLKGADFRVKDKAGRNFLHLVIFQPKGLKNLPENLLQSKAVRE---LMSDEDYEGCTPLHYACKLGIHDSVKNMLSQKICLGRKSKQKKSGLHFAAEYGRLNTCIRLLE-TISDSRLLNEGEENGLTPLHLASRGGHTKVVELLLRRGALFQS-DYKGWSCLHHAAAEGYTQTMVILLAANVKLLDYTNEEGNTALHLAARAGHVAAVKLLLNRGALFMLNKNGASFLHEAVRNGKKEVANAAIENERSSEALSL-FKKGPGFRCVVLDLIEFLPESTKHLLDLCMVESEHDPNNINYHIT-YNFKWLQAPILLKKYAKTDKSMNFQPLAALNAMVQYNRLELLTHPVCQKYLEMKWKAYGSKVHLLNLAVYLLGLLPLTYLIINLKPTQNTSVNGTTVTMASVSFRTQSYMISVC---IVMVLVMNVYAICK---ELVQLAQQRLIYFMDSTNVSDWASAISSLVFVIPLFFSVDNK-----WHWEAGALAILFAWINFLLYFQRFERFGIYVVMFGEIIKTLISTIVLFVFLLLAFGLSFYALMLHRVEFNSISLSLAQTFVMTVGELNYQNTLLEAYEQGQLAFPEISYFIFVLFVLLMPILLMNLMIGLAVGDIAEVQRNATLKRIAMQINLHTNLEEKLP 978
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Cavefish
Match: trpa1b (transient receptor potential cation channel subfamily A member 1 [Source:NCBI gene;Acc:103042231]) HSP 1 Score: 185.652 bits (470), Expect = 1.746e-47 Identity = 247/990 (24.95%), Postives = 415/990 (41.92%), Query Frame = 2
Query: 272 EAAISKNPELLEFILSKKPNI--NKKSCKGSTALLLAVKSGNAECVRLICKQKG-MEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHA-KCSPEVKDNNGISPIALAAS----------------------LGYL-----------EAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSL----SVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI--ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE---DIANELLNRGL-EVISDTNSVNKSLTKYHFFMLDA-------GPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDN-QGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNY------VVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDP---GFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYEP 3037
E + N LEF+ K P + ++ C G+ + A S N +RLI G E++ QD G+TP+ A N +LL GA+P LH I H +++LLL + +++ + G +P +A S LG+ EA + +Q I + IN D S A+R +I C+ GA ++ Q + ALH A G +E + + + + N D A +H +L +AE L+ A ++ + L+PLL L + K+++FL L AD ++KDK + LHL+I G E L Q E L++ D G PLH AC + ++S+ L + + +H A G L L++ I + NE E N + LA + GH + E L + S D G + L +A G + ++L + L N +T LH AA+AG V+ LL+ GA N + L A+ N A + + + FK G ++ E + LL+ + E D N++N +T Y+F L A D + + +Y + +L+ HP+ L KW+ +GS + +L +L L T++I + P S + V T + + S+ I M +M+++ + E ++ Q+L YF +N + L++ +FF+ K W G +AI+ W N + Y Q FGI ++MF ++ ++I I+LF+ L++ + ++FY + ++ F + S A+ + M +GEL+Y + L+ G F + + LF +L+ I L+NLM+G+AVGDI + +A + +QI + E LP + +P
Sbjct: 25 EWSCKGNISSLEFLSQKNPELLKSRDEC-GAGPIHHAAASANLAVIRLIVTVVGPEELNTQDDHGRTPLHWAVEKNQEGSCSLLLELGADPNILSLSLTAPLHLAISLEHNNLVQLLLLCDRTDVDLEGDLGNTPAMVACSNNNCQALQILFKYNAKLCHQNKLGHFAIHTVAFAGAKEAMEVILQKGEEMGITTSGHINYLDKSKSSPLHLAVRGGNTEVIKLCISKGAKVDQQQCDKSTALHFACTQGATEAVKIMLQPYERMEEIINIRDGANQTPLHRATLFDHVELAEYLVSKGADIDCIDCKGLSPLL----LATTCSAWKTVSFL---LLKGADFRVKDKAGRNFLHLVIFQPKGLKNLPENLLQSKAVRE---LMSDEDYEGCTPLHYACKLGIHDSVKNMLSQKICLGRKSKQKKSGLHFAAEYGRLNTCIRLLE-TISDSRLLNEGEENGLTPLHLASRGGHTKVVELLLRRGALFQS-DYKGWSCLHHAAAEGYTQTMVILLAANVKLLDYTNEEGNTALHLAARAGHVAAVKLLLNRGALFMLNKNGASFLHEAVRNGKKEVANAAIENERSSEALSL-FKKGPGFRCVVLDLIEFLPESTKHLLDLCMVESEHDPNNINYHIT-YNFKWLQAPILLKKYAKTDKSMNFQPLAALNAMVQYNRLELLTHPVCQKYLEMKWKAYGSKVHLLNLAVYLLGLLPLTYLIINLKPTQNTSVNGTTVTMASVSFRTQSYMISVC---IVMVLVMNVYAICK---ELVQLAQQRLIYFMDSTNVSDWASAISSLVFVIPLFFSVDNK-----WHWEAGALAILFAWINFLLYFQRFERFGIYVVMFGEIIKTLISTIVLFVFLLLAFGLSFYALMLHRVEFNSISLSLAQTFVMTVGELNYQNTLLEAYEQGQLAFPEISYFIFVLFVLLMPILLMNLMIGLAVGDIAEVQRNATLKRIAMQINLHTNLEEKLPYWYMKRVDKP 988
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Cavefish
Match: trpa1a (transient receptor potential cation channel subfamily A member 1-like [Source:NCBI gene;Acc:103022174]) HSP 1 Score: 179.874 bits (455), Expect = 1.420e-45 Identity = 231/951 (24.29%), Postives = 412/951 (43.32%), Query Frame = 2
Query: 353 GSTALLLAVKSGNAECVRLICKQKGM-EIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMI-KLLLHAKCSPEVKDNNGISPIALAASLGYLEAF--------YLC-------------------------IQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIP-------KLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMR-NHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWN-TAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANE----LLNRGL-EVISDTNSVNKSLTKYHFFMLDAGPY-----DSASVNSRYTEFMTI---AKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAI----FFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKI---FTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
G++ L A G+ ++LI + G E++ D +G TP+ A + + LL GA+P + LH + H ++ +L+ H++ + ++ + G +P+ LAAS+ EA LC +Q + ++I S IN D S A+R +I C+ +GA IN Q + ALH A G +E + ++CD IN D + LH +AE L+ A ++ + +PLL L + G +++ L L++ A++K++DK LHL I L ++++ E + LLN D G PLH AC + ++ +L + + +H A G + L++ + DE + + LA + GH + E L K HS D G + L +A G ++ +L + L + + +T LH AA+AG V LL GA+ N + L A+ N T+ V +D + F+ + K I++ + E LL+ + E D NS ++ +Y+F L + D+ + Y + ++ + +L+ HP+ L KW+ +G + ++I + + T++I + P + + + V S D + +T M +++M + + E ++ Q+L+Y + SN L+ +SS I F + + + W G +A ++ W N++ YLQ FGI ++MF+ + +++ II+LF+ L++ +A+AFY + Q F + S + + M++GE+ Y FL P F M + F +L+ I L+NL++G+AVGDI + +A + +QI S E LP
Sbjct: 45 GASPLHYAACKGHLRAIKLIVQIAGQQELNVVDEEGNTPLHWAVQKDQRGSCSALLSLGADPNILNKSLLSPLHLAVSLRHNGLVEQLVSHSQTNVNLEGDLGNTPVILAASVDNHEALCILQRNGAKLCRQNKLGHFPIHAAAFAGAKKTMEVVLQKGQEAGMSIESHINYVDKSISSPLHLAVRGGNLDVIQLCIAHGAKINQQQCDKSTALHFACTQGATEAVKLMLLAYDRVCDI---INITDGACQTPLHKATIFDHYELAEYLISQGADIDFIDCKGHSPLL----LATSCGAWRTVNLL---LSHGAELKVRDKAGCNFLHLAILQPR-GLKNLPTEVLQHESVRELLNDEDSEGCTPLHYACRLGIPDSVKNMLGLEVSLDQKSKQKKSALHFAAEYGRINTCHRLLEPMTDTRLLNEGDEKGMTPLHLASRGGHVKVVELLLRKGALFHS-DYKGWSCLHHAAAEGFTQTMETLLISNIKLLDKIDGDGNTALHLAARAGHVAAVRQLLCRGAQFVLNKGDASFLHEAVHNGRKEVTSAVIDSDRCEEAITTFKVNSAKR---CIVLDMIEFLPESYKHLLDTCIKESDDDVNSCTYNI-EYNFQWLQHTNHRIQNTDNIEEDDDYKPLAALNAMVEFNRVELLTHPVCKKFLEMKWKAYGMKAHLLNMIVYTLGVLPLTYLIVNLRPKLTVNKNVTTVT-MVTTSIDKQCYFITS---CMFLVLAMNTY-AVGKEIVQMFQQRLKYLRDMSN---LMDWSSTICSLLFVIPLLLNVESSWHWQAGALAGLISWINLLLYLQRFERFGIYVVMFREICRTLLSIIVLFIYLILAFALAFYALMVEQRHFGRMFLSLMQTFVMMVGEISYQDNFLKPYMSSQLPFPLMTYGIFVWFVLLVPILLMNLLIGLAVGDIAEVQTNACLKQIGMQIELHSNLEERLP 971 HSP 2 Score: 78.1814 bits (191), Expect = 4.037e-14 Identity = 107/462 (23.16%), Postives = 194/462 (41.99%), Query Frame = 2
Query: 638 VKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNG-ININ--------------SVDNNLDSAL---------------HLGIHNGSLSVA------------ECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAV--QSGHYNI-FEFLYFKDIE--MHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMY----ENTFHQTPLTLALDNQHWNTAKVFLN 1870
V+D+ G SP+ AA G+L A L +Q ++N+ D EG + A++ QR L GAD N+ + LH+A + + ++ +L + N+N SVDN+ + H IH + + A E + +H+N ++++ +PL +L + G +L ++L + + A + + K T LH G E ++L+ L+ + ++N D PLH A + ++ YLIS+GA++ + P+ AT G V L+ + ++ +R++ N + LA+ G N+ E L + + ++ +D G L YAC++G VK +L + +L ++ + + LH AA+ G+ LL + + TPL LA H ++ L
Sbjct: 40 VRDDTGASPLHYAACKGHLRAIKLIVQIAGQQELNV------VDEEGNTPLHWAVQKDQRGSCSALLSLGADPNILNKSLLSPLHLAVSLRHNGLVEQLVSHSQTNVNLEGDLGNTPVILAASVDNHEALCILQRNGAKLCRQNKLGHFPIHAAAFAGAKKTMEVVLQKGQEAGMSIESHINYVDKSISSPL----HLAVRGG---NLDVIQLCIAHGAKINQQQCDKSTALHFACTQGATEAVKLM--LLAYDRVCDIINITDGACQTPLHKATIFDHYELAEYLISQGADIDFIDCKGHSPLLLATSCGAWRTVNLLLS-HGAELKVRDKAGCNFLHLAILQPRGLKNLPTEVLQHESVRELLNDEDSEGCTPLHYACRLGIPDSVKNMLGLEVSLDQKSKQKKSALHFAAEYGRINTCHRLLEPMTDTRLLNEGDEKGMTPLHLASRGGHVKVVELLLR 485
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Cavefish
Match: trpa1a (transient receptor potential cation channel subfamily A member 1-like [Source:NCBI gene;Acc:103022174]) HSP 1 Score: 170.629 bits (431), Expect = 9.715e-43 Identity = 225/947 (23.76%), Postives = 400/947 (42.24%), Query Frame = 2
Query: 353 GSTALLLAVKSGNAECVRLICKQKGM-EIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMI-KLLLHAKCSPEVKDNNGISPIALAASLGYLEAF--------YLC-------------------------IQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIP-------KLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMR-NHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWN-TAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANE----LLNRGL-EVISDTNSVNKSLTKYHFFMLDAGPY-----DSASVNSRYTEFMTI---AKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKI---FTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILP 3007
G++ L A G+ ++LI + G E++ D +G TP+ A + + LL GA+P + LH + H ++ +L+ H++ + ++ + G +P+ LAAS+ EA LC +Q + ++I S IN D S A+R +I C+ +GA IN Q + ALH A G +E + ++CD IN D + LH +AE L+ A ++ + +PLL L + G +++ L L++ A++K++DK LHL I L ++++ E + LLN D G PLH AC + ++ +L + + +H A G + L++ + DE + + LA + GH + E L K HS D G + L +A G ++ +L + L + + +T LH AA+AG V LL GA+ N + L A+ N T+ V +D + F+ + K I++ + E LL+ + E D NS ++ +Y+F L + D+ + Y + ++ + +L+ HP+ L KW+ +G + ++I + + T++I + P + + + V S D +LK L D M+++M S+ + L++ + + + W G +A ++ W N++ YLQ FGI ++MF+ + +++ II+LF+ L++ +A+AFY + Q F + S + + M++GE+ Y FL P F M + F +L+ I L+NL++G+AVGDI + +A + +QI S E LP
Sbjct: 45 GASPLHYAACKGHLRAIKLIVQIAGQQELNVVDEEGNTPLHWAVQKDQRGSCSALLSLGADPNILNKSLLSPLHLAVSLRHNGLVEQLVSHSQTNVNLEGDLGNTPVILAASVDNHEALCILQRNGAKLCRQNKLGHFPIHAAAFAGAKKTMEVVLQKGQEAGMSIESHINYVDKSISSPLHLAVRGGNLDVIQLCIAHGAKINQQQCDKSTALHFACTQGATEAVKLMLLAYDRVCD---IINITDGACQTPLHKATIFDHYELAEYLISQGADIDFIDCKGHSPLL----LATSCGAWRTVNLL---LSHGAELKVRDKAGCNFLHLAILQPR-GLKNLPTEVLQHESVRELLNDEDSEGCTPLHYACRLGIPDSVKNMLGLEVSLDQKSKQKKSALHFAAEYGRINTCHRLLEPMTDTRLLNEGDEKGMTPLHLASRGGHVKVVELLLRKGALFHS-DYKGWSCLHHAAAEGFTQTMETLLISNIKLLDKIDGDGNTALHLAARAGHVAAVRQLLCRGAQFVLNKGDASFLHEAVHNGRKEVTSAVIDSDRCEEAITTFKVNSAKR---CIVLDMIEFLPESYKHLLDTCIKESDDDVNSCTYNI-EYNFQWLQHTNHRIQNTDNIEEDDDYKPLAALNAMVEFNRVELLTHPVCKKFLEMKWKAYGMKAHLLNMIVYTLGVLPLTYLIVNLRPKLTVNKNVTTVT-MVTTSIDKRLKYLRD----MSNLMDW------------------------SSTICSLLFVIPLLLNVE-----SSWHWQAGALAGLISWINLLLYLQRFERFGIYVVMFREICRTLLSIIVLFIYLILAFALAFYALMVEQRHFGRMFLSLMQTFVMMVGEISYQDNFLKPYMSSQLPFPLMTYGIFVWFVLLVPILLMNLLIGLAVGDIAEVQTNACLKQIGMQIELHSNLEERLP 941 HSP 2 Score: 77.7962 bits (190), Expect = 4.933e-14 Identity = 107/462 (23.16%), Postives = 194/462 (41.99%), Query Frame = 2
Query: 638 VKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNG-ININ--------------SVDNNLDSAL---------------HLGIHNGSLSVA------------ECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAV--QSGHYNI-FEFLYFKDIE--MHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMY----ENTFHQTPLTLALDNQHWNTAKVFLN 1870
V+D+ G SP+ AA G+L A L +Q ++N+ D EG + A++ QR L GAD N+ + LH+A + + ++ +L + N+N SVDN+ + H IH + + A E + +H+N ++++ +PL +L + G +L ++L + + A + + K T LH G E ++L+ L+ + ++N D PLH A + ++ YLIS+GA++ + P+ AT G V L+ + ++ +R++ N + LA+ G N+ E L + + ++ +D G L YAC++G VK +L + +L ++ + + LH AA+ G+ LL + + TPL LA H ++ L
Sbjct: 40 VRDDTGASPLHYAACKGHLRAIKLIVQIAGQQELNV------VDEEGNTPLHWAVQKDQRGSCSALLSLGADPNILNKSLLSPLHLAVSLRHNGLVEQLVSHSQTNVNLEGDLGNTPVILAASVDNHEALCILQRNGAKLCRQNKLGHFPIHAAAFAGAKKTMEVVLQKGQEAGMSIESHINYVDKSISSPL----HLAVRGG---NLDVIQLCIAHGAKINQQQCDKSTALHFACTQGATEAVKLM--LLAYDRVCDIINITDGACQTPLHKATIFDHYELAEYLISQGADIDFIDCKGHSPLLLATSCGAWRTVNLLLS-HGAELKVRDKAGCNFLHLAILQPRGLKNLPTEVLQHESVRELLNDEDSEGCTPLHYACRLGIPDSVKNMLGLEVSLDQKSKQKKSALHFAAEYGRINTCHRLLEPMTDTRLLNEGDEKGMTPLHLASRGGHVKVVELLLR 485
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 152.91 bits (385), Expect = 3.685e-38 Identity = 133/502 (26.49%), Postives = 230/502 (45.82%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLL 1771
LH AA S + +++E +L + I K+ G + L +A + + CV+L+ ++ +D TP+ +A + K+LL G P +G LH + N +++++LLL S +G++PI +A+ +G+L L +Q+ +S N+T+ G + A R Q ++ L+ GA + + E + LHIAS +G +EI+ L G + N+ + + L+ G VA LL N A ++ + TPL ++ S+ G +A L L +AD K+ + T LH+ H + LL +K +S NG PLH+A N ++ L+ GA + P+H A ++GH ++V L+ + I++ + + LA Q N+ E L ++++ + L A G+I MV +L+ + + + TPLHQAAQ G T +V LL
Sbjct: 275 LHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQA-PVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASS--------NATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPL----HIASKYG-RLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLL------DKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRH-ASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALL 755 HSP 2 Score: 139.813 bits (351), Expect = 4.634e-34 Identity = 160/631 (25.36%), Postives = 261/631 (41.36%), Query Frame = 2
Query: 272 EAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASV---------------------INSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGAN-------------------------LLLGNYNES--------LPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ---TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE-DIANELLNRGLEV 1990
AA + N E L L +IN + G AL LA K G+ + V + K++ EID + G T + +A DIV++L+ +GAN +G L+ + NHLE++K LL + V +G +P+A+A G+ + L ++S K+ + ++ + T G++ A Y + L GA ++ G LH+A++ G + ++ L D G I++ + + LH +G V E LL A + +N L+PL ++ +Q + LA ++LLL A V T LH+ GH +LL E + L NG PLH+AC N K+ L+ GA+ LLL N S P+H A+R G LE+VK L+ + ED+ L I A + G I + L + + ++ +G+ L +A + G + L+L+ ++ TPLH A++ G+ ++ LL A Q TPL +A H A + L+ ++ K G T + KN+ ++ LL G E
Sbjct: 17 RAARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREA-EIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPL----HMATQ---GEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARAL------NGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHI-ASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTA---KNGYTPLHIAAKKNQLEVGKVLLELGAET 629 HSP 3 Score: 100.138 bits (248), Expect = 1.107e-21 Identity = 92/360 (25.56%), Postives = 158/360 (43.89%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLH--AKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIA---------------------------SVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ 1258
+H A+ + +++ +L + N + +G T L +A ++G E V+ + Q G + + R+ QTP+ +A RL +IV++LL G++P G L+ R H ++ LLL A SP K G +P+ +A+ G LE L ++ ++ +A + +ST GY+ A + Q + L+ GA+ N+ +G LH+A++ G ++++ L +I+ +A+HL ++VAE L + A VN + TPL ++ S G K + FL L N A V K + T LH GH + L Q
Sbjct: 407 IHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLL-QSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTK--KGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPL----HVASHYGNIKMVNFL---LRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQ 756 HSP 4 Score: 98.2117 bits (243), Expect = 4.146e-21 Identity = 98/380 (25.79%), Postives = 167/380 (43.95%), Query Frame = 2
Query: 761 STDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQF----------------LLNSYDDNGDY-------PLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLA 1828
S + + FL A R +++ LK G DIN G NALH+AS+ G +++ +L I++ ++ALH+ G + L+ A++N ++N TPL +A E L +K LL+N A+ + + T L + + GH + + LL + + + + LL ++ N D PLH+A + L++ GA + N P+H A ++G+ +VK L+D +I + D + A +SGH + E L +D + +K + G + L A Q + V+L+L + + TPLH AA G ++ + LL G E + TPL +A
Sbjct: 6 SFQSDAATSFLRAARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQ-------ENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRG-AKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIA 377 HSP 5 Score: 73.559 bits (179), Expect = 1.619e-13 Identity = 79/339 (23.30%), Postives = 143/339 (42.18%), Query Frame = 2
Query: 212 KIWVQYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILL--YYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEA----FYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILEC----------------------LKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFL 1144
++ V+ ++ P LH A+ E+++ +L + + N + GST L A + G+ + L+ + G +I +KG TP+ +A + +++ +LL Y A+P + +G+ LH +H ++ LLL SP NG +P+ +AA LE L ++ M ++ +A ++ EG++ + + + +I L K+ AD+N LH+AS G +++ L N +N+ N + LH G V LL + A N N T L+ A + I V +L+ L
Sbjct: 461 RVGVKAREDQTP------LHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLL-ENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAP-LHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTA-LAIARRLGYISVVDTLSIL 790
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 149.828 bits (377), Expect = 7.776e-37 Identity = 134/511 (26.22%), Postives = 223/511 (43.64%), Query Frame = 2
Query: 353 GSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGY-SCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNE--------------DEANLII------------------LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE 1786
G T L A +SG+ + V ++ +Q G I + + G +P+ +A + + ++ V++L+ Y A D + LH H K+LL +P V+ NG +P+ +A + L L+ +I +V S + S F+ + I+L L+ GA N G+ ALH+A+ G +E++ L NG +++ + LH+ G L + + LL + A + N TPL ++ ++ G E A L L + A + + KK T LH+ G +E LL Q ++ NG PLHVA + +K+ L+ +GA+ N P+H A +K LEI L++ + I + D A+L++ LA Q N+ E L +++ + G L+ AC G+I MV +L+ ++ + + TPLHQAAQ G T +V LL GA
Sbjct: 6 GLTPLHCAARSGHEQVVEILLEQ-GAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMEL----LLKYGASIEAVTESGLTPMHVSAFMGNL-----NIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPL----HVAAREGHEDVTAIL---LEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASP------DAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGAR 493 HSP 2 Score: 130.954 bits (328), Expect = 4.675e-31 Identity = 115/412 (27.91%), Postives = 189/412 (45.87%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGA--NLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQIT 1495
+H +A N ++ +L + N + +G TAL +A ++G E VR + + G ++D + R+ QTP+ +A RL ++IV++LL + A+P + +G LH R H ++ +LL S V G +P+ +A+ G +E L +Q + ++ G + A Y + + L L GA + G LHIA++ EI L + G N++ + LHLG G VA LL +A VN ++ L+PL +L +Q E + ++L+ + A V K T L + G+I+ + L Q + +NS NG PLH A I N L+ GA N + N N +L I A R G++ +V L + + IT
Sbjct: 142 MHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRN-GAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASP--------DAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPL----HLAAQ---EDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGAD------VNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAI--ARRLGYISVVDTLKVVTEETIT 529 HSP 3 Score: 82.4185 bits (202), Expect = 3.897e-16 Identity = 71/289 (24.57%), Postives = 123/289 (42.56%), Query Frame = 2
Query: 248 NNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQ------------------SLMNSKINIASV-------INSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLV 1039
+N + LH AA + ++ +L ++ + KG T L +A K G E L+ Q+ D + G TP+ +A + + +LL GA+P + +G LH + + LE+ LL G++P+ L A G+ + L + + K+N+A + +N+T GY+ + A Y ++ L++GAD+N G LH A++ G + I+ L G N V N ++AL + G +SV + L V
Sbjct: 235 SNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLL-QRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTLKV 522 HSP 4 Score: 60.8474 bits (146), Expect = 1.782e-9 Identity = 55/214 (25.70%), Postives = 91/214 (42.52%), Query Frame = 2
Query: 1295 SYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLN--IQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTP---------------------------------LHQAAQAGQTKMVEYLLSIGAEM-YENTFHQTPLTLA 1828
++ +G PLH A + ++ L+ +GA +L N P+H AT+ H+E V+ L+ + IT+ D + +A GHY + L K + + G L AC+ I +++L+LK +++ TP LH AA+AGQT++V LL GA++ + QTPL +A
Sbjct: 1 AHRQDGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITL---DYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIA 211
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 147.902 bits (372), Expect = 1.744e-36 Identity = 134/502 (26.69%), Postives = 229/502 (45.62%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLL 1771
LH AA S + +++E +L + I K+ G + L +A + + CV+L+ ++ +D TP+ +A + K+LL G P +G LH + N +++++LLL S +G++PI +A+ +G+L L +Q+ +S N+T+ G + A R Q ++ L+ GA + + E + LHIAS +G +EI+ L G + N+ + + L+ G VA LL N A ++ + TPL ++ S+ G +A L L +AD K K T LH+ H + LL +K +S NG PLH+A N ++ L+ GA + P+H A ++GH ++V L+ + I++ + + LA Q N+ E L ++++ + L A G+I MV +L+ + + + TPLHQAAQ G T +V LL
Sbjct: 282 LHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQA-PVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASS--------NATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPL----HIASKYG-RLEVATLLLEKYASADPK--GKNGLTPLHVATHYDHQKVALLLL------DKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHAS-ISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALL 760 HSP 2 Score: 139.043 bits (349), Expect = 1.021e-33 Identity = 142/565 (25.13%), Postives = 237/565 (41.95%), Query Frame = 2
Query: 272 EAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASV-----------------------------INSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFH-QTPLTLALDNQHWNTAKVFLNDN 1876
AA + N E L L +IN + G AL LA K G+ + V + K++ EID + G T + +A DIV++L+ +GAN +G L+ + NHLE++K LL + V +G +P+A+A G+ + L ++S K+ + ++ +N T G++ A Y + L GA ++ G LH+A++ G + ++ L D G I++ + + LH +G V E LL A + +N L+PL ++ +Q + LA ++LLL A V T LH+ GH +LL E + L NG PLH+AC N K+ L+ GA++ + PIH A+ GHL +V Q+ ++N +N + + G L A + G + +VK +L+ + ++ TPLH A++ G+ ++V+ LL G++ T TPL A H + A + L +
Sbjct: 16 RAARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREA-EIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPL----HMATQ---GEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARAL------NGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVV---------QLLLQNGASSN-------------------------ATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENG 532 HSP 3 Score: 100.138 bits (248), Expect = 1.031e-21 Identity = 98/385 (25.45%), Postives = 168/385 (43.64%), Query Frame = 2
Query: 770 CEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ--------------------------LIKEEE-----KQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLA 1828
+ + FL A R +++ LK G DIN G NALH+AS+ G +++ +L I++ ++ALH+ G + L+ A++N ++N TPL +A E L +K LL+N A+ + + T L + + GH + + LL + L++ E + +LN ++G PLH+A + L++ GA + N P+H A ++G+ +VK L+D +I + D + A +SGH + E L +D + +K + G + L A Q + V+L+L + + TPLH AA G ++ + LL G E + TPL +A
Sbjct: 8 SDAATSFLRAARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQ-------ENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGA-KIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIA 384 HSP 4 Score: 98.9821 bits (245), Expect = 2.712e-21 Identity = 91/358 (25.42%), Postives = 158/358 (44.13%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLH--AKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSK-------------------------INIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ 1258
+H A+ + +++ +L + N + +G T L +A ++G E V+ + Q G + + R+ QTP+ +A RL +IV++LL G++P G L+ R H ++ LLL A SP K G +P+ +A+ G LE L ++ ++ ++ + +ST GY+ A + Q + L+ GA+ N+ +G LH+A++ G ++++ L +I+ +A+HL ++VAE L + A VN + TPL ++ S G K + FL L N A V K + T LH GH + L Q
Sbjct: 414 IHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLL-QSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTK--KGFTPLHIASKYGRLEVATLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPL----HVASHYGNIKMVNFL---LRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQ 761 HSP 5 Score: 69.707 bits (169), Expect = 2.585e-12 Identity = 77/306 (25.16%), Postives = 136/306 (44.44%), Query Frame = 2
Query: 233 DENHPNNTFNL-LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECL-KYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFL 1144
D N P + + L+ A+ + ++ +L +I+ + KG T L +A K G E L+ +K D + + G TP+ +A + + +LL GA+P + +G LH + N LE+ K+LL + G++P+ LAA G+ + L + ++ I++A+ +G ++ + + + E L K+ AD+N LH+AS G +++ L N +N+ N + LH G V LL + A N N T L+ A + I V +L+ L
Sbjct: 501 DPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLL-EKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGR--HASISLAT-------KGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTA-LAIARRLGYISVVDTLSIL 795
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007449.1 (pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007449.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 132.494 bits (332), Expect = 1.229e-31 Identity = 117/424 (27.59%), Postives = 193/424 (45.52%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGA--NLLLGNYNESLPIHEATRKGHLEIV---KDLIDLNIQQITIRNEDEANL 1522
+H +A N ++ +L + N + +G TAL +A ++G E VR + + G ++D + R+ QTP+ +A RL ++IV++LL + A+P + +G LH R H ++ +LL S V G +P+ +A+ G +E L +Q + ++ G + A Y + + L L GA + G LHIA++ EI L + G N++ + LHLG G VA LL +A VN ++ L+PL +L +Q E + ++L+ + A V K T L + G+I+ + L Q + +NS NG PLH A I N L+ GA N + N N +L I A R G++ +V K + + I T+ N N+
Sbjct: 52 MHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRN-GAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASP--------DAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPL----HLAAQ---EDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGAD------VNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAI--ARRLGYISVVDTLKVVTEETITSTTVSNPSSRNV 451 HSP 2 Score: 126.716 bits (317), Expect = 7.826e-30 Identity = 117/457 (25.60%), Postives = 187/457 (40.92%), Query Frame = 2
Query: 512 LLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNE--------------DEANLII------------------LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE 1786
LL GANP +G LH + N + +++LLL S E +G++P+ ++A +G L I+L L+ GA N G+ ALH+A+ G +E++ L NG +++ + LH+ G L + + LL + A + N TPL ++ ++ G E A L L + A + + KK T LH+ G +E LL Q ++ NG PLHVA + +K+ L+ +GA+ N P+H A +K LEI L++ + I + D A+L++ LA Q N+ E L +++ + G L+ AC G+I MV +L+ ++ + + TPLHQAAQ G T +V LL GA
Sbjct: 1 LLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLN-----------------------------------------IVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPL----HVAAREGHEDVTAIL---LEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASP------DAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGAR 403 HSP 3 Score: 108.612 bits (270), Expect = 3.076e-24 Identity = 108/413 (26.15%), Postives = 173/413 (41.89%), Query Frame = 2
Query: 311 ILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSA------------------NLISQIGV--------EKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLI 1471
+L K N N ++ G T L +A K + L+ K G I+ G TP+ ++ + ++IV ILL GA+P + G LH R+ E+++ LL + K +P+ +AA LG LE L +Q + + ++ GY+ A R + L++GA + + +G LH+AS+ G E+ L + ++ N + LH+ H + VA LL A + +N TPL +A N I++ GV E LLL ADV K + LHL + E+L + +N+ G PL VAC K+ N+L+ GA++ N P+H+A ++GH IV L+
Sbjct: 1 LLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKY-GASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASP--------DAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVK------HGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLL 398 HSP 4 Score: 82.8037 bits (203), Expect = 3.064e-16 Identity = 71/289 (24.57%), Postives = 123/289 (42.56%), Query Frame = 2
Query: 248 NNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQ------------------SLMNSKINIASV-------INSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLV 1039
+N + LH AA + ++ +L ++ + KG T L +A K G E L+ Q+ D + G TP+ +A + + +LL GA+P + +G LH + + LE+ LL G++P+ L A G+ + L + + K+N+A + +N+T GY+ + A Y ++ L++GAD+N G LH A++ G + I+ L G N V N ++AL + G +SV + L V
Sbjct: 145 SNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLL-QRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTLKV 432
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002048.1 (pep scaffold:Pmarinus_7.0:GL477431:30859:73495:1 gene:ENSPMAG00000001850.1 transcript:ENSPMAT00000002048.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 116.316 bits (290), Expect = 1.498e-26 Identity = 133/569 (23.37%), Postives = 234/569 (41.12%), Query Frame = 2
Query: 239 NHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDR--KGQ-TPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCF---LNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFH--QTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKT 1921
P+N L EA + + +L + ++++ + +G + L LA +G E +++ M + +DR KG TP+ A +DIV++LL +GA+ G L + +++++++LL A + E + +G +P+ AAS G++E L ++ + IN S +C+ L +R+ L+ GAD +E AL A G E+ L ++G +N ++ +S L L G + +A L+ A++ N TPL+ +A GH E + LL + + ++ + L +AC ++ ++LI GA+L LG S P+ EA ++GHLE+VK +L +H+ TG+ L YAC+ G + L+L+ +L+ + TPL +AA+AG V++L+S GA++ T + T L+LA H + ++ L N R K G T
Sbjct: 97 GQPDNRS--LAEACSDGDVNAVRKLLGEGRSVHETTEEGESLLCLACSAGYYELAQVLL---AMHANVEDRGVKGDITPLMAAASGGFVDIVRLLLAHGADVNAQSSTGNTALTYACAGGYVDVVRVLLEAGANLEDHNESGHTPLMEAASGGHVEVARLLLER--GAGINTHSNEFKESALTLACYKGHLEMVRF--------LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLESGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAR----------------------------------------EGHEEMVALLLA-----QGANINAQTEETQETALTLACCGGFLEVADFLIKAGADLELGC---STPLMEAAQEGHLELVK----------------------------------YLLAAGANVHATTATGDTALTYACENGHTDVADLLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGADVNRATANNDHTVLSLACAGGHLSVVELLLAHGADPN---HRLKDGST 565 HSP 2 Score: 97.4413 bits (241), Expect = 1.142e-20 Identity = 124/500 (24.80%), Postives = 201/500 (40.20%), Query Frame = 2
Query: 296 ELLEFILSKKPNINKKSCKGSTALLLAVKSGN-AECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQ-TILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQ-ITIRNEDEANLIIL--AVQSGHYNIFEFLYFKDIEMHSKDETGNN---ILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLL 1771
EL + +L+ N+ + KG L+A SG + VRL+ G +++ Q G T + AC +D+V++LL GAN G L H+E+ +LLL N S + +A C Y L +R+ L+ GAD +E AL A G E+ L ++G +N ++ +S L L G + +A L+ A++ N TPL+ +A + G E+ +A L L A++ + ++ Q T L L G +E + L + + E PL A ++ YL++ GAN+ + A GH D+ DL +Q + +E E L A ++GH +FL K +++ T NN +L AC G + +V+L+L + R ST L +AA+ G T +V YL+
Sbjct: 147 ELAQVLLAMHANVEDRGVKGDITPLMAAASGGFVDIVRLLLAH-GADVNAQSSTGNTALTYACAGGYVDVVRVLLEAGANLEDHNESGHTPLMEAASGGHVEVARLLLERGAGINTHSNE-----------------------FKESALTLA-------C--YKGHLEMVRF--------LLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLESGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAA----REGHEEMVALL---LAQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADLELGC---------STPLMEAAQEGHLELVKYLLAAGANVHATTATGDTALTYACENGH----TDVADLLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGADVNRA--TANNDHTVLSLACAGGHLSVVELLLAHGADPNHRLKDGSTMLIEAAKGGHTSVVCYLI 583 HSP 3 Score: 93.5893 bits (231), Expect = 1.645e-19 Identity = 89/330 (26.97%), Postives = 157/330 (47.58%), Query Frame = 2
Query: 296 ELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQ-DRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNN--GISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININS--VDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKE 1270
+L+ ++++ NI + KG T L+LA +G+ V L+ G +I+ Q +R TP+ LAC ++V++L+ GAN L ++ +IK+LL+A + + GISP+ LAA G+ A L + M S IN N +CF R++ ++++E A++ G L A+ G++E+ L + G ++N+ V ++ D+AL + G E ++ AH++V N+ TPL +AN L ++LL+N+ ADV D +K T L GH++ + L + + +
Sbjct: 947 DLVTVLIARGANIEHRDKKGFTPLILAATAGHVNVVELLL-DNGADIEAQSERTKDTPLSLACSGGRQEVVELLIARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLD--MGSDINAQIETNRNTALTLACFQG--RHEVVSLLVE---RKANVEHRAKTGLTPLMEAASGGYAEVGRVLLERGADVNAAPVPSSRDTALTIAADKGHYKFCELVISRGAHIDVRNKKGNTPLWLAAN-------GGHLDVVQLLVNSGADVDAADNRKITPLMAAFRKGHVKVVRYLVKEVNQ 1261 HSP 4 Score: 85.1149 bits (209), Expect = 6.270e-17 Identity = 77/292 (26.37%), Postives = 139/292 (47.60%), Query Frame = 2
Query: 1166 ADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNI-LMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYEN---TFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHM------GYIIMKNEDIANELLNRGLEVISDTN 2005
A+++ +DKK T L L +GH+ +ELL + E Q + D PL +ACS +++ LI+ GAN N ++ P+ A G++ I+K L++ + I R + + ++LA +GH + L +++++ ET N L AC G +V L++++ N++ R TPL +AA G ++ LL GA++ + T LT+A D H+ ++ ++ ++ R K G T + G++ D+ L+N G +V + N
Sbjct: 957 ANIEHRDKKGFTPLILAATAGHVNVVELLLDNGADIEAQ-----SERTKDTPLSLACSGGRQEVVELLIARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAE-INSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRHEVVSLLVERKANVEHRAKTGLTPLMEAASGGYAEVGRVLLERGADVNAAPVPSSRDTALTIAADKGHYKFCELVISRGAH---IDVRNKKGNTPLWLAANGGHL-----DVVQLLVNSGADVDAADN 1234 HSP 5 Score: 76.6406 bits (187), Expect = 2.567e-14 Identity = 90/343 (26.24%), Postives = 153/343 (44.61%), Query Frame = 2
Query: 359 TALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGAN-PMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKN-ALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKS-LAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISE 1378
TAL LA G+ + V ++ +G I+ +D+KG TP+ LA +++V++LL GA+ +SE L E+++LL+ + E ++ + +P++LAAS GY+ I+ L+N+ I S S G S + A + L G+DIN +N AL +A G E++ L + N+ + L G V LL A VN P+ SS + I +K F +L+++ A + +++KK T L L GH++ ++LL + +++ D+ PL A K+ YL+ E
Sbjct: 935 TALTLACAGGHEDLVTVLIA-RGANIEHRDKKGFTPLILAATAGHVNVVELLLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLIARGANKEHRNVSDYTPLSLAASGGYVN----IIKILLNAGAEINSRTGSK--LGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRHEVVSLLVERKANVEHRAKTGLTPLMEAASGGYAEVGRVLLERGADVNAA------PVPSSRDTALTIAADKGHYKFCELVISRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVNSGAD------VDAADNRKITPLMAAFRKGHVKVVRYLVKE 1258 HSP 6 Score: 73.9442 bits (180), Expect = 1.435e-13 Identity = 76/320 (23.75%), Postives = 143/320 (44.69%), Query Frame = 2
Query: 836 LKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININS-VDNNLDSALHLGIHNGSLSVAECLLV---NHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIAS--GHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLID--LNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLL 1771
+ GA+I +G L +A+ G ++ L DNG +I + + D+ L L G V E L+ N H NV + L+ L +S ++ +K+LLN A++ + K I L++A+ GH ++LL + + Q + N + L +AC ++ + L+ AN+ P+ EA G+ E+ + L++ ++ + + + L I A GHY E + + + +++ GN L A G + +V+L++ ++ ++ + TPL A + G K+V YL+
Sbjct: 953 IARGANIEHRDKKGFTPLILAATAGHVNVVELLLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLIARGANKEHRNVSDYTPLS-LAASGGYVN---------IIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQI-----ETNRNTALTLACFQGRHEVVSLLVERKANVEHRAKTGLTPLMEAASGGYAEVGRVLLERGADVNAAPVPSSRDTALTI-AADKGHYKFCELVISRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVNSGADVDAADNRKITPLMAAFRKGHVKVVRYLV 1256 HSP 7 Score: 63.929 bits (154), Expect = 1.817e-10 Identity = 52/162 (32.10%), Postives = 80/162 (49.38%), Query Frame = 2
Query: 1400 NYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLY--FKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ---TPLTLALDNQHWNTAKVFLN 1870
N++ +L + A GH ++V LI I R++ +ILA +GH N+ E L DIE S + T + L AC G +V+L++ + N + RN TPL AA G +++ LL+ GAE+ T + +PL LA N H K+ L+
Sbjct: 932 NHDTALTL--ACAGGHEDLVTVLIARGAN-IEHRDKKGFTPLILAATAGHVNVVELLLDNGADIEAQS-ERTKDTPLSLACSGGRQEVVELLIARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLD 1089 HSP 8 Score: 58.5362 bits (140), Expect = 7.742e-9 Identity = 61/242 (25.21%), Postives = 103/242 (42.56%), Query Frame = 2
Query: 1301 DDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLID--LNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQ--STPLHQAAQAGQTKMVEYLLSIGAEMYEN--TFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHM------GYIIMKNEDIANELLNRGLEV 1990
+ N D L +AC+ + LI+ GAN+ + P+ A GH+ +V+ L+D +I+ + R +D + LA G + E L + ++ + L A G + ++K++L + R + +PL AA G T V+ LL +G+++ T T LTLA + + K +E R KTG T + GY ++ LL RG +V
Sbjct: 930 ESNHDTALTLACAGGHEDLVTVLIARGANIEHRDKKGFTPLILAATAGHVNVVELLLDNGADIEAQSERTKD--TPLSLACSGGRQEVVELLIARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRHEVVSLLV---ERKANVEHRAKTGLTPLMEAASGGYA-----EVGRVLLERGADV 1161
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Yeast
Match: AKR1 (Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats; AKR1 has a paralog, AKR2, that arose from the whole genome duplication; any of several human homologs encoding DHHC-type zinc fingers (ZDHHC) can complement temperature sensitivity of yeast akr1 null mutant [Source:SGD;Acc:S000002672]) HSP 1 Score: 65.855 bits (159), Expect = 2.509e-11 Identity = 45/166 (27.11%), Postives = 85/166 (51.20%), Query Frame = 2
Query: 1322 LHVACSNNLRKICNYLISEGANL-LLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGH-----YNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENT 1801
LH A NN + ++L+S+GA++ + P+H A R G++ IV D + + T+ ++ NL+ L+V S + Y +F + +++ +D G L++A GD V +LK ++++ + TPLH GQ +++YL+ GA+ ++ T
Sbjct: 113 LHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIV-DFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPLHWGTVKGQPHVLKYLIQDGADFFQKT 277
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Yeast
Match: AKR2 (Ankyrin repeat-containing protein; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; possibly involved in constitutive endocytosis of Ste3p; AKR2 has a paralog, AKR1, that arose from the whole genome duplication [Source:SGD;Acc:S000005560]) HSP 1 Score: 62.3882 bits (150), Expect = 2.899e-10 Identity = 56/233 (24.03%), Postives = 99/233 (42.49%), Query Frame = 2
Query: 374 AVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSE-YDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNR 1069
A K G+ + V+ + + ++I+ + + AC N + K LL GANP ++ G LH R ++ ++ LLL P +KD G++ + + + + ++N+ N+ I+S D + L A + LK+G+ + N G NALH A G +I L +G N +N L G+ S+ E L +H + + N+
Sbjct: 57 AAKDGDLKVVKDVVESGAVDINNDRIDELSGLHWACINNRFSVAKFLLLRGANPNQAAGPGGATALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVD--IDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVICDLILSGANFYERNNQKQDCFDLAEGMGTKSLFEQALQHHGYDRLGNQ 287 HSP 2 Score: 49.6766 bits (117), Expect = 2.495e-6 Identity = 43/165 (26.06%), Postives = 78/165 (47.27%), Query Frame = 2
Query: 1322 LHVACSNNLRKICNYLISEGANL-LLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYF------KDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYE 1795
LH AC NN + +L+ GAN + +H A R G++ IV DL+ + T+++E N++ +V S + + ++ + ++++ SKD L++A GD V+L+LK + ++ LH A G +++ L+ GA YE
Sbjct: 88 LHWACINNRFSVAKFLLLRGANPNQAAGPGGATALHWAARYGNIYIV-DLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVICDLILSGANFYE 251
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Yeast
Match: NAS6 (Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, also known as p28, which interacts with the Rb tumor suppressor and CDK4/6 [Source:SGD;Acc:S000003464]) HSP 1 Score: 57.3806 bits (137), Expect = 1.853e-9 Identity = 57/221 (25.79%), Postives = 98/221 (44.34%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILSKKPNIN-KKSCKGSTALLLAVKSGNAECVR-LICKQKGMEIDG-QDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYD-----GMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAF-YLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQ-RTIILECLKYGADINLAQNEGKNALHIA 898
LH+A + ++ +L KP++ +K G L +V E L+ K + + +D D G TP +AC + +++VK L P+K + + G+ CLH + E+ + L+ S +KD P+ AAS+G L+ LC S +N D +G++ +A+ +L KYGA+ +L N+G A +A
Sbjct: 6 LHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLY---DRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLG--------KSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVA 215
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Yeast
Match: GDE1 (Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes [Source:SGD;Acc:S000006031]) HSP 1 Score: 55.4546 bits (132), Expect = 4.197e-8 Identity = 42/146 (28.77%), Postives = 74/146 (50.68%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFIL-SKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRK-GQTPIDLACRLNMIDIVKILLYYGAN-PMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYL 694
LH + +P+ E +L S PN+ KS S+ L LA + N + ++ K +I+ QD + +TP+ LACRLN + LLY GA+ ++ + G + +++KLL+ + +++D G +P+ A G+L
Sbjct: 477 LHLCVLGAHPKTTEVLLQSLDPNVKLKS---SSLLHLATEWNNYPLLHVLLSSKRFDINYQDNELHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHL 619
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Yeast
Match: AVO2 (Component of a complex containing the Tor2p kinase and other proteins; complex may have a role in regulation of cell growth [Source:SGD;Acc:S000004672]) HSP 1 Score: 50.8322 bits (120), Expect = 7.076e-7 Identity = 30/99 (30.30%), Postives = 50/99 (50.51%), Query Frame = 2
Query: 1178 LKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLID 1474
+K K T +HL + GH +T+ LL Q +N +NG P+H+AC N+ + + LI GA+L + + N P+H G + +K L++
Sbjct: 70 IKTFKGNTCVHLALMKGHEQTLHLLLQQFPR-----FINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLN 163
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Nematostella
Match: EDO27354 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9H1]) HSP 1 Score: 126.331 bits (316), Expect = 3.458e-30 Identity = 95/410 (23.17%), Postives = 194/410 (47.32%), Query Frame = 2
Query: 1589 MHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEM-YENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNK-LKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAK--VKDPMCTI---QWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDY 2797
++++D L A G + L+L K+ + ++ + P + + +V+ L+ GA++ N +T L +A+D + AKV + + W + R G+ M +I D+A L++ + S +H +LD GP + +E M + E+L+ HP++ LL KW FG + L+ FL ++ F++ I DS + P ++ + + L+ S ++ ++ +F + + E + +L YFK +N V L++Y+ AI F + ++P+ T W+ G + + L + NV+ Y++ I + G+ + M+ V S +K+I +FL +++G + +Y++ + + F ++F + + M++GE+DY
Sbjct: 99 LNARDLDLQTPLHVAAARGSPESINLLLGKNCTIDAKDANDQYPFYIV----EVNIVKLCLAEGADVTXRNKDDKTCLDVAIDWKRTEVAKVLIQHDRWWEVICTRNSAGELPMVGLIEALPDVAKLALDQCIVRCPLPTSHQDYCLTFHTVLLDPGPCKEGQTSRDASEVMV--ENDCEELLSHPVTQGLLRYKWFAFGKVPYYIYLMVFLIFVILFSYFIITER----DSSTLYHPTHPNASALEKQYLEKRPSSTNSITIVLILFATIEFLKEFYQIFMIRLDYFKDITNLVELVLYTCAIIFISPYLAEEPLYTAAYGHWNAGVVTLFLAYLNVLLYIKGIGSSGLYVTMYFEVWYSFLKVITVFLVVLLGSTLVYYLLLKEEDDFSGVHYAFVRTFVMMVGEIDY 498
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Nematostella
Match: EDO39112 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB40]) HSP 1 Score: 92.8189 bits (229), Expect = 2.976e-19 Identity = 78/294 (26.53%), Postives = 137/294 (46.60%), Query Frame = 2
Query: 1196 QTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVA---CSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAV--QSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEM-YENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGP 2059
+T LH+ A T+E++ + + ++NS D G PLH A C KI LI GAN+L +++E LP+H A +G L+ + L+ N + TI D +L L + + L K E+ +D+ L Y VG VK++L+ D +L+ R+ ++ TPL AA G+ ++ LL GA++ E + L +ALDN + + + +WK + G + + +I + +A +L++ +E + ++ + Y F +L P
Sbjct: 4 RTCLHVAAACSDFRTVEIILR----NGGKSIINSKDSYGKTPLHYAVIRCQGG--KIIQLLIESGANVLAVDFDERLPLHHAAEQGMLDNISILLQANPE--TINEVDNRSLTALHIAAAAARTEACRLLLEKGAEVDYRDDERLTPLFYVASVGCPLTVKVLLEYDADLEARDKNRKTPLISAAYFGRLEVFRTLLDSGADIAAETSSGWNALDVALDNNNLDITNEIIRHESWKTLLLNTKADGVSPLKKLIERVPCLAKVVLDKCIEHSTWVDTDKEYSVTYDFQLLSPPP 289 HSP 2 Score: 50.447 bits (119), Expect = 4.082e-6 Identity = 55/226 (24.34%), Postives = 99/226 (43.81%), Query Frame = 2
Query: 359 TALLLAVKSGNAECVRLICKQKGMEI-DGQDRKGQTPIDLAC-RLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEV---KDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSV 1021
T L +A + V +I + G I + +D G+TP+ A R I+++L+ GAN + ++D LHH L+ I +LL A +PE DN ++ + +AA+ EA L ++ + ++ D E + + L+Y AD+ K L A+ G E+ L D+G +I + ++ +AL + + N +L +
Sbjct: 5 TCLHVAAACSDFRTVEIILRNGGKSIINSKDSYGKTPLHYAVIRCQGGKIIQLLIESGANVLAVDFDERLPLHHAAEQGMLDNISILLQA--NPETINEVDNRSLTALHIAAAAARTEACRLLLEK--------GAEVDYRDDERLTPLFYVASVGCPLTVKVLLEYDADLEARDKNRKTPLISAAYFGRLEVFRTLLDSGADIAAETSSGWNALDVALDNNNLDI 220
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Nematostella
Match: EDO33180 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST04]) HSP 1 Score: 87.0409 bits (214), Expect = 1.460e-17 Identity = 91/381 (23.88%), Postives = 170/381 (44.62%), Query Frame = 2
Query: 1601 DETGNNILMYACQVGDIGMVKLILKKDFNL--QMRNHHQSTPLHQAAQAGQTKMVEYLLS-IGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFM-TIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAK--VKDPMCTIQWS---FGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIV 2716
D G L +A G + V+LI + N N Q T LH AA+ G +++V++LLS ++ N ++Q L +A++ N V N W+ M R + G T + ++++K A + L+R +E + S+T + F L P ++ + + T+ KY++ + H + ++ KW G ++ +L +L +L T M I D N + + I +MS+F L+ E + +K +Y + N++ +Y S++ + + V D ++ AI + W + YL+ FGI I+M N++ ++IKII+LF+ +I + I F+++
Sbjct: 15 DTEGRTALHFAAAKGSLRSVQLICMANPNCINDEDNADQDTSLHLAAKNGHSEVVDFLLSDPNQKITYNGYNQNGLDVAIEAGRENVVMVIANHTRWRE-MCHRVEEGLTQLQHLVIKMPSAAEKFLDRCVEECGAGKDEDYSVT-FDFMFLQGMPDIRKDDPKKFLDCLHTMVKYKRVNCLSHQVCGAIMNIKWRSVGWKAYVMNLTFYLIFLLLLTSMTIMLDARIED----------------NLVIDIPKYTII---VMSLFHLLK---ELFQIWDEKFKYLLKADNWMEWFLYMSSLVYMIQYEVFDNHVSVTGETRPLAATAIFIAWVIFVLYLRRFSTFGIYIIMMTNIIKTLIKIIILFIPFVIAFGIPFFLL 371
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Nematostella
Match: EDO41103 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5D6]) HSP 1 Score: 76.2554 bits (186), Expect = 1.137e-14 Identity = 52/183 (28.42%), Postives = 100/183 (54.64%), Query Frame = 2
Query: 2537 WSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLD----------------PGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYEP 3037
W G+ A++L + N + +L+ + FG+ I M+ V+ S+IK++++F+ ++ +A+AFY + + Q F++F +SF K + M++ +DY + +D P F +F + F ILI I L+NL++G+AVGDID + A + +++ Y++ + LP+ +P
Sbjct: 161 WPLGSTAMLLCFTNAILFLRRVHVFGLYISMYIEVLKSLIKVLMVFILFILAFALAFYCLLKEQDAFKSFKWSFLKTFMMMVNGMDYQTTIVDSLGEHNPVSGAPLVPVPSFTVFIMVL------FVILIVILLVNLLIGLAVGDIDAIRQTANLRQLAMEVEYVANLDERLPKRFLKALQKP 337
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Nematostella
Match: EDO39113 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB41]) HSP 1 Score: 71.633 bits (174), Expect = 3.753e-14 Identity = 53/192 (27.60%), Postives = 93/192 (48.44%), Query Frame = 2
Query: 476 ACRLNMIDIVKILLYYGANPMKS-EYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGIS---PIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGA-DINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLL 1036
ACR D V+ LL + + + DG LH+ +NH++++++LL A +V+ + I PI AA +E+ + +++ + +N T+C G + +A R ++ L+ G D+N+ + +LH+A+ IG + II L G NI + DN+ +A HL G V + LL
Sbjct: 2 ACRDGRKDCVRKLLRGNLTNLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRA--------GADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLL 185 HSP 2 Score: 55.0694 bits (131), Expect = 1.780e-8 Identity = 31/107 (28.97%), Postives = 53/107 (49.53%), Query Frame = 2
Query: 296 ELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLL 616
E +L ++N +C G TAL A + G+++ V L+ + M+++ DR T + +A + I+K LL+ GAN + DG H R E+++ LL
Sbjct: 79 ESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLL 185 HSP 3 Score: 47.7506 bits (112), Expect = 5.294e-6 Identity = 46/180 (25.56%), Postives = 78/180 (43.33%), Query Frame = 2
Query: 941 NGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNR---NLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLI 1471
N N+N++D + S LH + + + LL A V+V + P++ +A + +E L+ ADV + + QT LH GH + +ELL + + Q +N D + LHVA I L+ GAN+ + + H A R+G E+++ L+
Sbjct: 18 NLTNLNTLDADGFSPLHYATTTNHVDIVQMLLDAGADVDVRGSPSIQRIPPIICAAKFNA---IESCRVLLRAG----ADVNITNCYGQTALHHATRRGHSKMVELLLR-----DGQMDVNVVDRDNTTSLHVAAMIGSNPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLL 185 HSP 4 Score: 46.9802 bits (110), Expect = 8.456e-6 Identity = 40/177 (22.60%), Postives = 79/177 (44.63%), Query Frame = 2
Query: 329 NINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQT---PIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLH-AKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYG 847
N+N G + L A + + + V+++ G ++D + PI A + N I+ ++LL GA+ + G LHH R H +M++LLL + V D + + + +AA +G ++ + + + I + D +G++ F A R + ++ L+ G
Sbjct: 21 NLNTLDADGFSPLHYATTTNHVDIVQMLL-DAGADVDVRGSPSIQRIPPIICAAKFNAIESCRVLLRAGADVNITNCYGQTALHHATRRGHSKMVELLLRDGQMDVNVVDRDNTTSLHVAAMIGS--------NPIIKTLLFCGANITAKDNDGFTAFHLAAREGEEEVLQTLLRTG 188
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Medaka
Match: trpa1b (transient receptor potential cation channel subfamily A member 1 [Source:NCBI gene;Acc:101174541]) HSP 1 Score: 196.438 bits (498), Expect = 7.333e-51 Identity = 245/995 (24.62%), Postives = 436/995 (43.82%), Query Frame = 2
Query: 266 LHEAAISKNPELLEFILS--KKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYD-GMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSL----SVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLI--ASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLG--NYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANL--IILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL-QMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE---DIANELLNRGLEVISDTNSVNKSLTKYHFFMLDA--GPYDSASVNSRYTEFMTI---AKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPI--ADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAI----FFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFK---IFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYEP-VFVYKQMRRSVFQRFFSELDSGNQQ-------IESASEN 3133
LH AA + L++FI++ +N +G+ L AV+ E R + G + + + +P+ LA L D++K+LL Y A + D G L N+ E + +LL ++ G P+ AA G +A + +++ A IN D S A+R I C+ GA I+ QN+ LH+A G +E++ + + N D A +H ++ +AE L+ A +N C+ TPLL L + G K +A L L+ A+V LKDK LHL I G E ++++ + LL+ D+ G PLH AC + ++ L L + ++ +H A + G + + L++ + DE L + LA + GH + + L K HS D G + L +A G + ++L + L + +T LH AA+AG V +L GAE+ N H + L A+ N + ++ + + ++ F G + I+ E + LL+ + D ++ +Y+F L A P + + + + + KY + +L+ HP+ L KW +GS ++ +L L T +I P + D+ D+ PV + KS + + M IM+++ + E ++ Q+ YF+ SN+ ++SA+ F + + ++ W G +A++ W + YLQ N GI ++MF ++ ++++I++LF LM+ +++AF+ + NQ+ F+ S + + M++GEL+Y + LD K F + + F +L+ I L+NLM+G+AVGDI + +A + +QI + E LP + +P + +Y R + F + L SG ++ ++S S+N
Sbjct: 64 LHHAAAGGHVTLIQFIITVLDPKELNCSDDQGNVPLHWAVERNKPESCRALL-DLGADPNVLNTALLSPLHLAVSLRQNDLMKLLLSYNATDCNLQGDLGNTPLMMACSINNCEALTILLKHGAKLCQQNKLGHFPMHAAAFAGAKKAMEVILKAGEEHGHPAAVHINYLDKSNSSPLHLAVRGGNIEAIRLCIATGAKIDQQQNDRSTPLHLACTQGATEVVKLMLSTVDQVEDFINLTDGACQTPLHRATIFDHSELAEYLISLGADLNSCDCKGNTPLL----LATSCGAWKCVALL---LSKGANVNLKDKCGCNFLHLAIHQPKGLKNIPE---EVLQRNSVKALLSCEDNEGCTPLHYACRLGIHDSVKNMLGLSGQLGLACKSKDKKSALHFAAQYGRINTCQRLLETITDSRLLNEGDERGLTPLHLASKEGHTKVVQLLLRKGALFHS-DYKGWSCLHHAASEGYTQTMAILLSANLKLLDKTDEDGNTALHIAARAGHVAAVRLMLVKGAELVLNKNHTSFLHEAVQNGRKDVVNAVVDSDRCEEALQL-FTPGTSQRCPILDMIEFLPETYKHLLDCCVRESDDDHNSPDYHIEYNFQWLQAPISPQKLSDESLKIQPLVAVNAMVKYNRIELLNHPVCKKYLAMKWVAYGSKAHALNMFLYLLGLLPLTHLIVSLRPSMNTTDTGDHVINMVPVSFTEQTVFKSFS---MVMVLIMNIYSIGK---EIVQLSQQRWNYFRDHSNHND---WASAVYSLLFIIPLMINAEGSLHWQAGALAVLHYWIGFLLYLQRFENVGIFVVMFGEIMRTLVRIVMLFFFLMLAFSLAFHALMLNQSQFETVPLSVIQTFVMMVGELNYQNNILDAFLKNELPFGILTYFIFVQFVMLMPILLVNLMIGLAVGDIAEVQRNASLKRIAMQIDLHTSLEDKLPYWFMKRVDKPSIIIYPN--RKCSRHFLTHLFSGEEEKNEVWSRLQSKSQN 1034 HSP 2 Score: 55.4546 bits (132), Expect = 3.741e-7 Identity = 57/239 (23.85%), Postives = 99/239 (41.42%), Query Frame = 2
Query: 1181 KDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIR--------------NEDEANLIILAVQS--------GHYNIFEF----------LYFKDIEMHSK---------DETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLS 1774
KD+ + LH A GH+ I+ + ++ +E LN DD G+ PLH A N + C L+ GA+ + N P+H A +++K L+ N ++ N EA I+L + GH+ + + K E H D++ ++ L A + G+I ++L + + + + +STPLH A G T++V+ +LS
Sbjct: 56 KDECGASPLHHAAAGGHVTLIQFIITVLDPKE----LNCSDDQGNVPLHWAVERNKPESCRALLDLGADPNVLNTALLSPLHLAVSLRQNDLMKLLLSYNATDCNLQGDLGNTPLMMACSINNCEALTILLKHGAKLCQQNKLGHFPMHAAAFAGAKKAMEVILKAGEEHGHPAAVHINYLDKSNSSPLHLAVRGGNIEAIRLCIATGAKIDQQQNDRSTPLHLACTQGATEVVKLMLS 290
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Medaka
Match: ank1b (ankyrin-1 [Source:NCBI gene;Acc:101157380]) HSP 1 Score: 155.221 bits (391), Expect = 1.063e-37 Identity = 155/598 (25.92%), Postives = 260/598 (43.48%), Query Frame = 2
Query: 236 ENHPN------NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLF----QLIKEEEKQFL-----------------------LNSYDDNGDYPLHVACSNNLRKICNYLISEG-------------------------ANLLLGNYN----ESL----PIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQT-PLTLA 1828
+N PN F LH AA +N + + +L++ N+N G T L +A + GN VRL+ +G +ID Q + TP+ A R + I++ILL +GA +G+ +H + +H++ ++ LL + + ++P+ +AA G+ + ++ + N+ G++ A + + LK+ A + G LH+A+ +G I+ L G + N+ + +++ LH+ G VA+ LL N A V+ ++ TPL +A + + +KLLL++ A+ T LH+ GHI TI +L Q +K +K F N+ NG PLHVA +N + L+S+G A++LL N ESL P+H A+++G ++V LI + + N++ + L Q GH I + L + +++ G L AC G+I MVK +L++ ++ + TPLHQAAQ G T +V LL GA E T + T PL +A
Sbjct: 192 QNDPNPDVLSKTGFTPLHIAAHYENMSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVMMVRLLL-DRGAQIDAQTKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGH--------HRMAKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKNLLQRGASPNASNVKVETPLHMASRAGHCEVAQFLLQNAAQVDARAKDDQTPLHCAARMGHK-------ELVKLLLDHKANPDSATTAGHTPLHIAAREGHIHTIRILLDAGAQQVKMTKKGFTPLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSAHSTARNGYTPLHIAAKQNQIEVASVLLQNGASPNCESLQGITPLHLASQEGRPDMVAMLISKQA-NVNLGNKNGLTPLHLVAQEGHVGIADTLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNAKTRMGYTPLHQAAQQGHTDIVTLLLKHGALPNEITSNGTSPLGIA 772 HSP 2 Score: 140.584 bits (353), Expect = 2.909e-33 Identity = 146/574 (25.44%), Postives = 241/574 (41.99%), Query Frame = 2
Query: 329 NINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINI--------------ASVINSTDC-------EGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE-DIANELLNRG 1981
NIN + G L LA K G+ + V L G+E++ +KG T + +A +V L+ YGAN + G L+ + NHLE++K LL + + +G +P+A+A G+ L I K+ + A+V+ D G++ A Y+ ++ L GA++N G LHIAS G ++ L D G I++ + + LH NG + + E LL + A + +N L+P+ +A V + L + NA++ T LH+ GH ++L +K N+ NG PLH+AC N + + L+ A+L + P+H A GHL IVK+L+ N + +A ++GH + +FL ++ ++ + L A ++G +VKL+L N TPLH AA+ G + LL GA+ + T TPL +A + A++ L N K G T + + N D+ L+++G
Sbjct: 35 NINIANQNGLNGLHLASKEGHVKMV-LELLHSGIELEATTKKGNTALHIAALAGQEKVVAELVNYGANVNAQSHKGFSPLYMAAQENHLEVVKFLLENGANQSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENMSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVMMVRLLLDRGAQIDAQTKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQY-------NAEIDDITLDHLTPLHVAAHCGHHRMAKVLL------DKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKNLLQRGASP-NASNVKVETPLHMASRAGHCEVAQFLLQNAAQVDARAKDDQTPLHCAARMGHKELVKLLLDHKANPDSATTAGHTPLHIAAREGHIHTIRILLDAGAQQVKMTKKGFTPLHVASKYGKVDVAELLLERGANPNAA---GKNGLTPLHVAVHHNNLDVVKLLVSKG 590 HSP 3 Score: 105.916 bits (263), Expect = 1.527e-22 Identity = 110/429 (25.64%), Postives = 187/429 (43.59%), Query Frame = 2
Query: 770 CEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQF----------------LLNSYDDNGDY-------PLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGY-IIMKNEDIANELLNRG 1981
+ + FL A R L+ +K G +IN+A G N LH+AS+ G +++ +L +GI + + ++ALH+ G V L+ A+VN + +PL +A E L +K LL N A+ L + T L + + GH + LL + + + +L D N D PLH+A + L++ GAN+ N P+H A+R+G++ +V+ L+D QI + +DE + A ++GH I E L + +K + G + + A Q + V+ +L+ + + TPLH AA G +M + LL GA+ + TPL +A H + + L + ++E ++G T + M + +I LL RG
Sbjct: 8 ADAATSFLRAARSGNLDKALDHIKNGININIANQNGLNGLHLASKEGHVKMVLELLHSGIELEATTKKGNTALHIAALAGQEKVVAELVNYGANVNAQSHKGFSPLYMAAQ-------ENHLEVVKFLLENGANQSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENMSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVMMVRLLLDRGA-QIDAQTKDELTPLHCAARNGHVRIIEILLEHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHS---ASLEAVTESGLTPLHVAAFMGHLNIVKNLLQRG 425 HSP 4 Score: 103.99 bits (258), Expect = 4.968e-22 Identity = 119/510 (23.33%), Postives = 222/510 (43.53%), Query Frame = 2
Query: 353 GSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGK---NALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTF-HQTPLTLALDNQHWNTAKVFLN 1870
+T+ L A +SGN + L + G+ I+ ++ G + LA + + +V LL+ G + G LH + +++ L++ + + + G SP+ +AA +LE +++ N + +G++ A++ ++ + YG +GK ALHIA+ + L N N + + + LH+ H ++SVA+ LL A+VN +N +TPL ++ S+ G ++ ++LLL+ A + + K + T LH +GH+ IE+L E + + NG P+H+A + L+ A + + P+H A GH + K L+D + R + + +A + H + L + + E+G L A +G + +VK +L++ + N TPLH A++AG ++ ++LL A++ QTPL A H K+ L+
Sbjct: 10 AATSFLRAARSGNLDKA-LDHIKNGININIANQNGLNGLHLASKEGHVKMVLELLHSGIELEATTKKGNTALHIAALAGQEKVVAELVNYGANVNAQSHKGFSPLYMAAQENHLEVVKFLLENGANQSLPTE--------DGFTPLAVALQQGHENVVALLINYG-------TKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENMSVAQLLLNRGANVNFTPKNGITPL----HIASRRG---NVMMVRLLLDRGAQIDAQTKDELTPLHCAARNGHVRIIEILL------EHGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGA-KANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKNLLQRGASPNASNVKVETPLHMASRAGHCEVAQFLLQNAAQVDARAKDDQTPLHCAARMGHKELVKLLLD 489 HSP 5 Score: 72.7886 bits (177), Expect = 2.114e-12 Identity = 59/248 (23.79%), Postives = 107/248 (43.15%), Query Frame = 2
Query: 257 FNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLE---------AFYLCIQSLMNSKINIA----------------SVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEII 925
F LH A+ ++ E +L + N N G T L +AV N + V+L+ KG R G TP+ +A + N I++ +LL GA+P G+ LH + +M+ +L+ + + + + NG++P+ L A G++ A + + +++A + +N+ GY+ A + I+ LK+GA N + G + L IA +G+ +I
Sbjct: 535 FTPLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVS-KGGSAHSTARNGYTPLHIAAKQNQIEVASVLLQNGASPNCESLQGITPLHLASQEGRPDMVAMLISKQANVNLGNKNGLTPLHLVAQEGHVGIADTLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNAKTRMGYTPLHQAAQQGHTDIVTLLLKHGALPNEITSNGTSPLGIAKRLGYISVI 781
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Medaka
Match: ENSORLT00000031565.1 (ankyrin 2 [Source:NCBI gene;Acc:101161458]) HSP 1 Score: 152.525 bits (384), Expect = 6.752e-37 Identity = 142/567 (25.04%), Postives = 246/567 (43.39%), Query Frame = 2
Query: 248 NNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTG---KTHMGYI 1936
N LH A+ N ++ +L + I+ K+ G T L A +SG+ V ++ +KG + + + G +P+ +A + + ++ VK LL + A D + LH H + KLLL + +P + NG +P+ +A ++ L ++ + + S + + LN I+L L+ GA +++ G+ +LH+A+ G +E++ L NG +++ + LH+ G + + LL + AH + N TPL SA E L +LL A L KK T LH++ G ++ +LL Q +Q +S NG PLHVA + +K+ L+ +GA+ N P+H A +K ++I L+ + + + L LA Q GH ++ L K +++ ++G L A Q + + +++++ NL + TPL A G KMV +LL GA + T + TPL A + + V L N + T +GYI
Sbjct: 272 RNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLL-EKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLN--------IVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAR-------EGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQ------RQAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLH-LASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAVTVNGNTALGIARRLGYI 815 HSP 2 Score: 122.865 bits (307), Expect = 9.492e-28 Identity = 131/549 (23.86%), Postives = 232/549 (42.26%), Query Frame = 2
Query: 224 QYIDENH------PNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCK--GSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKI-----NIASVINST-------------DCEGYSCFLN---AIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGA 1783
QY E H ++ + L A ++LE++ K ++ +C G AL LA K G+ + V+ + +G +D +KG T + ++ ++VK L+ GA+ +G L+ + NHL++++ LL + +G +P+A+A G+ + + +++ K+ +IA+ + T D + S F A Y + L GA ++ G LH+AS+ G + ++ L D G I++ + + LH +G + E LL A + +N L+PL ++ +Q + + L DV L T LH+ GH +LL +K+ N+ NG PLH+AC N K+ L+ GA++ + PIH A GHL IV L+ N + N + +A ++G + L + ++ L A ++G +V+L+L+ + + TPLH +A+ GQ + LL GA
Sbjct: 32 QYFCEEHVPAEMLSDSNTSFLRAARAGNIDKVLEYL---KGGVDISTCNQNGLNALHLAAKEGHMDLVQELL-DRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPL----HMAAQGDHVECVKHLLQHKAPVDDVTL---DYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQ-NGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGA 562 HSP 3 Score: 96.2857 bits (238), Expect = 1.406e-19 Identity = 108/434 (24.88%), Postives = 178/434 (41.01%), Query Frame = 2
Query: 782 SCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ---------------LIKEEEKQ-FLLNSYDDNGDY-------PLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQ----------------VGDIGM-----------------VKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKT 1912
+ FL A R +LE LK G DI+ G NALH+A++ G +++ +L D G ++S ++ALH+ G V + L+ A +N ++N TPL +A E L ++ LL N + + T L + + GH + + +L + K++ K LL D N D PLH+A + L++ GA + N P+H A+++G+ +V+ L+D QI + D + A +SGH E L K + ++ + G + L A Q V D+ + KL+L K N R + TPLH A + + K++E L+ GA + T TP+ +A H N + L + + R +T
Sbjct: 49 TSFLRAARAGNIDKVLEYLKGGVDISTCNQNGLNALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQ-------ENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRG-SQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGET 474
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Medaka
Match: ENSORLT00000039458.1 (ankyrin 2 [Source:NCBI gene;Acc:101161458]) HSP 1 Score: 150.599 bits (379), Expect = 2.874e-36 Identity = 142/567 (25.04%), Postives = 246/567 (43.39%), Query Frame = 2
Query: 248 NNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTG---KTHMGYI 1936
N LH A+ N ++ +L + I+ K+ G T L A +SG+ V ++ +KG + + + G +P+ +A + + ++ VK LL + A D + LH H + KLLL + +P + NG +P+ +A ++ L ++ + + S + + LN I+L L+ GA +++ G+ +LH+A+ G +E++ L NG +++ + LH+ G + + LL + AH + N TPL SA E L +LL A L KK T LH++ G ++ +LL Q +Q +S NG PLHVA + +K+ L+ +GA+ N P+H A +K ++I L+ + + + L LA Q GH ++ L K +++ ++G L A Q + + +++++ NL + TPL A G KMV +LL GA + T + TPL A + + V L N + T +GYI
Sbjct: 257 RNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLL-EKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLN--------IVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAR-------EGQLETASVLLEAGASHSLATKKGFTPLHVVSKYGSLDVAKLLLQ------RQAPPDSAGKNGLTPLHVAAHYDNQKVALLLLDKGASPHTTAKNGYTPLHIAAKKNQMDIATVLLQYGAETNALTKQGVTPLH-LASQEGHADMAALLMSKGAQINVPTKSGLTALHLAAQEDRVAVAEILVRNGANLDHQTKLGYTPLIVACHYGNAKMVSFLLQNGASVNAKTKNGYTPLHQAAQQGNTHIINVLLQHGAKPNAVTVNGNTALGIARRLGYI 800 HSP 2 Score: 139.428 bits (350), Expect = 8.744e-33 Identity = 130/512 (25.39%), Postives = 229/512 (44.73%), Query Frame = 2
Query: 248 NNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGA 1783
N N LH AA + +L++ +L + ++ + KG+TAL ++ +G AE V+ + K +G +I+ Q + G TP+ +A + N +D+V+ LL G N + DG L ++ H +++ +LL +V+ + + +AA ++ L +Q+ N+ + S G++ A Y + L GA ++ G LH+AS+ G + ++ L D G I++ + + LH +G + E LL A + +N L+PL ++ +Q + + L DV L T LH+ GH +LL +K+ N+ NG PLH+AC N K+ L+ GA++ + PIH A GHL IV L+ N + N + +A ++G + L + ++ L A ++G +V+L+L+ + + TPLH +A+ GQ + LL GA
Sbjct: 63 QNGLNALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVK-RGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVR----LPALHIAARKDDTKSAALLLQNDHNADVQSKS--------GFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPL----HMAAQGDHVECVKHLLQHKAPVDDVTL---DYLTALHVAAHCGHYRVTKLLL------DKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQ-NGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQLETASVLLEAGA 547 HSP 3 Score: 94.7449 bits (234), Expect = 3.780e-19 Identity = 106/434 (24.42%), Postives = 178/434 (41.01%), Query Frame = 2
Query: 782 SCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQ---------------LIKEEEKQ-FLLNSYDDNGDY-------PLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETG----------------NNILMYACQVGDIGM-----------------VKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKT 1912
+ FL A R +LE LK G DI+ G NALH+A++ G +++ +L D G ++S ++ALH+ G V + L+ A +N ++N TPL +A E L ++ LL N + + T L + + GH + + +L + K++ K LL D N D PLH+A + L++ GA + N P+H A+++G+ +V+ L+D QI + D + A +SGH E L K + ++ + G ++L + V D+ + KL+L K N R + TPLH A + + K++E L+ GA + T TP+ +A H N + L + + R +T
Sbjct: 34 TSFLRAARAGNIDKVLEYLKGGVDISTCNQNGLNALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAEVVKTLVKRGADINAQSQNGFTPLYMAAQ-------ENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRG-SQIDAKTRDGLTPLHCAARSGHEASVEVLLEKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGET 459 HSP 4 Score: 85.1149 bits (209), Expect = 3.044e-16 Identity = 115/499 (23.05%), Postives = 207/499 (41.48%), Query Frame = 2
Query: 440 GQDRKGQTPID------LACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDN---------GININSVDNNLDSA--------------------LHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFH-QTPLTLA 1828
GQ RK D A R ID V L G + +G+ LH + H+++++ LL + G + + +++ G E ++ + + + IN+ G++ A + ++ L+ G + + A +G L IA + G ++++ L +N ++I + ++ SA LH+ H G+++VA LL A V+ RN +TPL ++ S+ G + ++LLL+ + + K + T LH SGH ++E+L EK L + NG PLH+A + + +L+ A + + +H A GH + K L+D R + + +A + + E L + + E+G + A +G + +V L+L+ + + N T LH AA+AGQ ++V LL GA + QTPL +A
Sbjct: 21 GQRRKRPKKSDSNTSFLRAARAGNIDKVLEYLKGGVDISTCNQNGLNALHLAAKEGHMDLVQELLDRGAPVDSSTKKGNTALHISSLAGQAE--------VVKTLVKRGADINAQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPL----HVASKRG---NTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHEASVEVLL------EKGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANP-NARALNGFTPLHIACKKNRVKVMELLVKYGASIQAVTESGLTPIHVAAFMGHLNIVLLLLQNGASPDVSNIRGETSLHMAARAGQAEVVRCLLRNGAMVDARAREDQTPLHIA 497
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Medaka
Match: ank1a (ankyrin-1 [Source:NCBI gene;Acc:101174837]) HSP 1 Score: 129.028 bits (323), Expect = 1.280e-29 Identity = 141/587 (24.02%), Postives = 248/587 (42.25%), Query Frame = 2
Query: 257 FNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDR-------------KGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLM--NSKIN--------------------IASVI-------NSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEK---------------------QFLL------NSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLII---LAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENT 1801
F L+ AA + E+++F+L N + + G T L +A++ G+ V L+ G+ R G TP+ +A +++ ++LL GAN D + LH R+ H +I++LL + K NG+SPI +AA +++ C++ L+ N++I+ +A V+ NS G++ A + ++ LK+ A I G LH+AS +G I+ L G + ++ + +++ LH+ +G VAE LL N A V+ ++ TPL +A + + +KLLL + A+ + LH+ GH++T+ LL + ++ K + LL N+ NG PLHVA +N + N L+S+G + N +H A ++ +E+ L+ Q N + + LA Q G +I L K ++ +++G L Q G +G+ +++K+ ++ TPLH A G KMV++LL A + T
Sbjct: 107 FTPLYMAAQENHLEVVKFLLENGANQSIPTEDGFTPLAVALQQGHENVVALLIS---YGTKGKVRLPALTDFCFFLSVTGFTPLHIAAHYENLNVAQLLLNRGAN------DELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMD----CVKQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSASIEAVTESGLTPLHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQNAAPVDAKAKDDQTPLHCAARMGHK-------ELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTALHIAAKQNQVEVANSLL----QHGASANAESLQGVTPLHLASQEGRPDIVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQQANVNSKT 669 HSP 2 Score: 126.716 bits (317), Expect = 5.824e-29 Identity = 136/562 (24.20%), Postives = 242/562 (43.06%), Query Frame = 2
Query: 329 NINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQ---NEGKN----ALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGA---EMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNE-DIANELLNRG 1981
+IN + G AL LA K G+ + V L G+ ++ +KG T + +A +V L+ YG N G L+ + NHLE++K LL + + +G +P+A+A G+ L I K+ + ++ + + FL+ + L + ++N+AQ N G N LH A+ G II L DNG I + N S +H+ + + LL +A ++ + LTPL ++ + G + K+LL+ A + T LH+ H+ ++LL + + + ++G PLHVA I L+ +GA+ N P+H A+R GH E+ + L+ N + + +D+ + A + GH + + L +S G++ L A + G + V+L+L + TPLH A++ G+ + E LL GA +N TPL +A+ + + + + ++ ++ + G T + +N+ ++AN LL G
Sbjct: 32 DINTANQNGLNALHLASKEGHVKMV-LELLHNGIVLETTTKKGNTALHIAALAGQEQVVTELVNYGTNVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQSIPTEDGFTPLAVALQQGHENVVALLISYGTKGKVRLPALTD------FCFFLSVTGFTP----LHIAAHYENLNVAQLLLNRGANDELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQLLQYNAEIDDITLDHLTPL----HVAAHCGHHR---MAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLK------HSASIEAVTESGLTPLHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQ-NAAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPLHVASKYGKVDVAELLLERGANPNAAGKNGL--TPLHVAVHHNNLDVVNLLVSKGGSPHSAA---RNGYTALHIAAKQNQVEVANSLLQHG 563 HSP 3 Score: 124.02 bits (310), Expect = 4.526e-28 Identity = 116/481 (24.12%), Postives = 204/481 (42.41%), Query Frame = 2
Query: 248 NNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNL 1690
N+ LH AA + + ++E +L I K+ G + + +A + + +CV+ + Q EID TP+ +A + K+LL GA P +G LH + NHL ++ LLL S E +G++P+ +A+ +G+L + +Q + + V S + L+ A ++ + + LH A+ +G E++ L ++ N NS S LH+ G + LL A + TPL ++ S+ G + +LLL A+ K T LH+ + +++ + LL K +S NG LH+A N ++ N L+ GA+ + P+H A+++G +IV LI + + N+ + L Q GH I + L + +++ G L AC G+I MVK +L++ N+
Sbjct: 208 NDELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQLL-QYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSASIEAVTESGLTPLHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEF--------LLQNAAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPL----HVASKYG---KVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVS------KGGSPHSAARNGYTALHIAAKQNQVEVANSLLQHGASANAESLQGVTPLHLASQEGRPDIVSLLISKQA-NVNLGNKSGLTPLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQQANV 665 HSP 4 Score: 117.087 bits (292), Expect = 5.289e-26 Identity = 140/565 (24.78%), Postives = 236/565 (41.77%), Query Frame = 2
Query: 230 IDENHPN-NTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVK-----------DNNGISPIALAASLGYLEAFYLCIQSLMNSKINI-------------------ASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQ-TPLTLA 1828
ID N N N N LH A+ + +++ +L + + KG+TAL +A +G + V + G ++ Q +KG TP+ +A + N +++VK LL GAN DG L ++ H ++ LL+ +V+ G +P+ +AA L L + N ++ + I + G S A + + + L+Y A+I+ + LH+A+ G + L D G NS N + LH+ L V + LL + A + + LTPL ++ S +G L +K+LL A + K +T LH+ SGH E E L Q + + + DD PLH A +++ L+ AN P+H A R+GH++ V+ L+D+ QQ + + L + A + G ++ E L + ++ + G L A ++ +V L++ K + + T LH AA+ Q ++ LL GA + TPL LA
Sbjct: 31 IDINTANQNGLNALHLASKEGHVKMVLELLHNGIVLETTTKKGNTALHIAALAGQEQVVTELVNY-GTNVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQSIPTEDGFTPLAVALQQGHENVVALLISYGTKGKVRLPALTDFCFFLSVTGFTPLHIAAHYENLNVAQLLLNRGANDELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSASIEAVTESGLTPL----HVASFMG---HLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQNAAPVDAK----AKDDQ--TPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPLHV-ASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTALHIAAKQNQVEVANSLLQHGASANAESLQGVTPLHLA 580 HSP 5 Score: 105.531 bits (262), Expect = 1.999e-22 Identity = 108/397 (27.20%), Postives = 169/397 (42.57%), Query Frame = 2
Query: 788 FLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEE--------------------------------KQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLN--IQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAE-MYENTFHQTPLTLALDNQHWNTAKVFLND 1873
FL A R LE +K G DIN A G NALH+AS+ G +++ +L NGI + + ++ALH+ G V L+ +VN ++ TPL +A E L +K LL N A+ + + T L + + GH + LL + + Q LLN ++ PLH A N +I L+ GA + N PIH A + H++ VK L+ N I IT+ D + +A GH+ + + L K + +S+ G L AC+ + ++ L+LK +++ TPLH A+ G +V+ LL GA N +TPL +A + H+ A+ L +
Sbjct: 11 FLRAARSGNLDKALEHIKNGIDINTANQNGLNALHLASKEGHVKMVLELLHNGIVLETTTKKGNTALHIAALAGQEQVVTELVNYGTNVNAQSQKGFTPLYMAAQ-------ENHLEVVKFLLENGANQSIPTEDGFTPLAVALQQGHENVVALLISYGTKGKVRLPALTDFCFFLSVTGFTPLHIAAHYENLNVAQLLLNRGANDELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQLLQYNAEIDDITL---DHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSASIEAVTESGLTPLHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQN 397
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Planmine SMEST
Match: SMESG000070631.1 (SMESG000070631.1) HSP 1 Score: 1856.26 bits (4807), Expect = 0.000e+0 Identity = 984/1047 (93.98%), Postives = 988/1047 (94.36%), Query Frame = 2
Query: 2 MTEVEVDSNLLTHKHFHLYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNGLMDNLKTVEPKIWVQYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYEPVFVYKQMRRSVFQRFFSELDSGNQQIESASENTFF 3142
MT+VEVDSNLLTHKHFHLYPFFKFSSRSFSSSKDKEKEKILKSFQRHQVLLQLLHAVQNGLMDNLKTVEPKIWVQYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKG+EID QDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKLLLNNNADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLW NVMFYLQTIPNFGIPILMFK K ++ G PF F IFTAMKLILVTLFSILISISLINLMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYEPVFVYKQMRRSVFQRFFSELDSGNQQIESASENTFF
Sbjct: 1 MTKVEVDSNLLTHKHFHLYPFFKFSSRSFSSSKDKEKEKILKSFQRHQVLLQLLHAVQNGLMDNLKTVEPKIWVQYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGLEIDSQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKLLLNNNADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWTNVMFYLQTIPNFGIPILMFKKCCFERDKDNIIVSGTDDRIRNRILYRKSESNPFSKFL--------------------------IFTAMKLILVTLFSILISISLINLMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFYEPVFVYKQMRRSVFQRFFSELDSGNQQIESASENTFF 1021 HSP 2 Score: 87.4261 bits (215), Expect = 4.159e-17 Identity = 40/46 (86.96%), Postives = 42/46 (91.30%), Query Frame = 1
Query: 2632 QKCCFERDKDNIIVSGTDDRIRNRILYRKSESNPFSKFLVFICKTL 2769
+KCCFERDKDNIIVSGTDDRIRNRILYRKSESNPFSKFL+F L
Sbjct: 878 KKCCFERDKDNIIVSGTDDRIRNRILYRKSESNPFSKFLIFTAMKL 923
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Planmine SMEST
Match: SMESG000070631.1 (SMESG000070631.1) HSP 1 Score: 1701.8 bits (4406), Expect = 0.000e+0 Identity = 874/878 (99.54%), Postives = 876/878 (99.77%), Query Frame = 2
Query: 2 MTEVEVDSNLLTHKHFHLYPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNGLMDNLKTVEPKIWVQYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFK 2635
MT+VEVDSNLLTHKHFHLYPFFKFSSRSFSSSKDKEKEKILKSFQRHQVLLQLLHAVQNGLMDNLKTVEPKIWVQYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKG+EID QDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKLLLNNNADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLW NVMFYLQTIPNFGIPILMFK
Sbjct: 1 MTKVEVDSNLLTHKHFHLYPFFKFSSRSFSSSKDKEKEKILKSFQRHQVLLQLLHAVQNGLMDNLKTVEPKIWVQYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGLEIDSQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKLLLNNNADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDNQGCPVDNSTDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPMCTIQWSFGTIAIILLWTNVMFYLQTIPNFGIPILMFK 878 HSP 2 Score: 92.8189 bits (229), Expect = 8.391e-19 Identity = 44/46 (95.65%), Postives = 45/46 (97.83%), Query Frame = 1
Query: 2632 QKCCFERDKDNIIVSGTDDRIRNRILYRKSESNPFSKFLVFICKTL 2769
+KCCFERDKDNIIVSGTDDRIRNRILYRKSESNPFSKFLVFI KTL
Sbjct: 878 KKCCFERDKDNIIVSGTDDRIRNRILYRKSESNPFSKFLVFIFKTL 923
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Planmine SMEST
Match: SMESG000078033.1 (SMESG000078033.1) HSP 1 Score: 511.146 bits (1315), Expect = 1.228e-163 Identity = 328/959 (34.20%), Postives = 538/959 (56.10%), Query Frame = 2
Query: 176 NGLMDNLKTVEPKIWVQYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRG-LEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDN-QGCPVDNS--TDNKLKSLTDSEITMNSIMSMFGFLRLINESLKFLSQKLQYFKRGSNYVVLLMYSSAIFFTAKVKDPM---CTIQWSFGTIAIILLWKNVMFYLQTIPNFGIPILMFKNVVSSVIKIILLFLGLMIGYAIAFYIVNRNQTPFQNFWFSFAKLYDMLIGELDYVSYFLDPGFKIFTAMKXXXXXXXXXXXXXXXXXXMVGIAVGDIDRMMNDAKISMKILQITYLSETESILPRALQAKFY 3031
+G + L++V K+W + ++ N F+LLH A + + +++ F+L KP++N + LA + G+ E V L+CK K ID D KGQTP+ ACR +++VKILL Y A+ K E D + +HHP+R N +M+K+L+ V++NNG +P+ +AA G+ E F L + + NI S++N D +G+SC +A++ + II C+ D++ QN+GK H A+ IG+SE+ + N ++N DN L++ +H I N +L + + LL A++NVCNR+ TP++ + I+Q + +K L NA++K+KD + +TI H LI +IE +E Q + E L+NS DD+ + PLH A +IC L+ GA+ L + N+ L +H AT KGHL+ V L++ + + R+ +E + I LA ++G Y IF+ L + SKD+ G N LM+A + G + +V+ +L + N+ + + +ST LHQAA+ G +V+ L GA++ E+ F T L +A+ NQ W+ + FLN+ NWK M FR + G H+ +I NE+I ELL++ +E +S+ N + K+ F +LD+GP D AS++ RY ++A + L+ HPLS LL KW +FG F++ D I +L +L + Y P+ D+ Y + GC NS + +KL + + MNS++ +L+ LK SQ++++F NY+ + FF +K+P+ C +W F I ++W +++Y++ P GI ++MF+ V+ S+IK +F GL +G+ FYI+N +Q PF+ K M+IGEL+ VSYF+ G K + + ++ F I++ I+ NLM+G+AVGDI + +A++ M L++ ++ E ES LP Q Y
Sbjct: 55 HGYLQFLQSVPLKVWAKRLNVIDEKNNFSLLHYACLENHKDIVSFLLIFKPDVNVIGANKIRPIHLAAQQGHMEIVELLCKYKSTHIDAADVKGQTPLHTACRRGHLNVVKILLKYQASVQKLELDSISVMHHPVRRNDTDMVKVLVAYGSPLNVRNNNGQTPLMVAAIEGHFELFDLLLNEMKKQGENIISILNEKDNDGFSCLSHAVQNENSEIIKICIGNAVDLDAKQNDGKTIFHSAAIIGYSELFDLIETNSYHLNITDNELNTPIHHAIMNNNLKMVKLLLDKGANINVCNRHFQTPIMLACIEITQ--SRNTAEIIKTLNQANANLKIKDFEMKTIFHYLIEKENIEMLEYFTQTLNSEILLELINSQDDSHNSPLHCAAKIGNAEICQILLKAGADPFLFSQNDFLALHVATIKGHLDCVIILLEASKETSYYRDANENSAINLAAENGRYEIFKHLVDIGKDKMSKDDFGRNTLMFAAKSGCLPIVEDLLNDEVNINLYDQMKSTALHQAAERGHLDIVKLLWKQGAKLSEDMFGSTQLDVAILNQQWHVVRFFLNNENWKKVMNFRHQNGHGHIKVLIKYNEEITLELLDKCIIENMSNVMDPNYEI-KFWFGILDSGPDDKASISKRYLALKSMADCGQLDLLKHPLSEKLLQCKWNKFGLAFYLIDFIVYLLFLICINVYMSIY-TPMTDTDSYTSYSGCKQTNSSVSSDKLDAPV-GVVLMNSLIYAIITGQLLLLLLKLFSQRIRFFMEVWNYIFITNDILVFFF---IKNPLQLPCLYEWQFAPGLIFVVWFLLLYYMRFFPYIGIQVMMFQKVLVSIIKAFAIFFGLFVGFGFGFYIINSSQDPFKTQGLGIIKSIAMMIGELEIVSYFV-TGKKNYANVSYAMIVCFMIIMPITFFNLMIGLAVGDISNVNAEAELEMIKLRVNFVWEMESQLPVRWQRILY 1004
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Planmine SMEST
Match: SMESG000078033.1 (SMESG000078033.1) HSP 1 Score: 424.861 bits (1091), Expect = 1.088e-133 Identity = 251/718 (34.96%), Postives = 406/718 (56.55%), Query Frame = 2
Query: 176 NGLMDNLKTVEPKIWVQYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLAFLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELLFQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRG-LEVISDTNSVNKSLTKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKWERFGSFFWMTDLITFLAYLGFFTFMIFHYMPPIADSPDYDN-QGCPVDNST 2323
+G + L++V K+W + ++ N F+LLH A + + +++ F+L KP++N + LA + G+ E V L+CK K ID D KGQTP+ ACR +++VKILL Y A+ K E D + +HHP+R N +M+K+L+ V++NNG +P+ +AA G+ E F L + + NI S++N D +G+SC +A++ + II C+ D++ QN+GK H A+ IG+SE+ + N ++N DN L++ +H I N +L + + LL A++NVCNR+ TP++ + I+Q + +K L NA++K+KD + +TI H LI +IE +E Q + E L+NS DD+ + PLH A +IC L+ GA+ L + N+ L +H AT KGHL+ V L++ + + R+ +E + I LA ++G Y IF+ L + SKD+ G N LM+A + G + +V+ +L + N+ + + +ST LHQAA+ G +V+ L GA++ E+ F T L +A+ NQ W+ + FLN+ NWK M FR + G H+ +I NE+I ELL++ +E +S+ N + K+ F +LD+GP D AS++ RY ++A + L+ HPLS LL KW +FG F++ D I +L +L + Y P+ D+ Y + GC NS+
Sbjct: 55 HGYLQFLQSVPLKVWAKRLNVIDEKNNFSLLHYACLENHKDIVSFLLIFKPDVNVIGANKIRPIHLAAQQGHMEIVELLCKYKSTHIDAADVKGQTPLHTACRRGHLNVVKILLKYQASVQKLELDSISVMHHPVRRNDTDMVKVLVAYGSPLNVRNNNGQTPLMVAAIEGHFELFDLLLNEMKKQGENIISILNEKDNDGFSCLSHAVQNENSEIIKICIGNAVDLDAKQNDGKTIFHSAAIIGYSELFDLIETNSYHLNITDNELNTPIHHAIMNNNLKMVKLLLDKGANINVCNRHFQTPIMLACIEITQ--SRNTAEIIKTLNQANANLKIKDFEMKTIFHYLIEKENIEMLEYFTQTLNSEILLELINSQDDSHNSPLHCAAKIGNAEICQILLKAGADPFLFSQNDFLALHVATIKGHLDCVIILLEASKETSYYRDANENSAINLAAENGRYEIFKHLVDIGKDKMSKDDFGRNTLMFAAKSGCLPIVEDLLNDEVNINLYDQMKSTALHQAAERGHLDIVKLLWKQGAKLSEDMFGSTQLDVAILNQQWHVVRFFLNNENWKKVMNFRHQNGHGHIKVLIKYNEEITLELLDKCIIENMSNVMDPNYEI-KFWFGILDSGPDDKASISKRYLALKSMADCGQLDLLKHPLSEKLLQCKWNKFGLAFYLIDFIVYLLFLICINVYMSIY-TPMTDTDSYTSYSGCKQTNSS 768
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Planmine SMEST
Match: SMESG000078036.1 (SMESG000078036.1) HSP 1 Score: 399.438 bits (1025), Expect = 2.030e-125 Identity = 240/673 (35.66%), Postives = 384/673 (57.06%), Query Frame = 2
Query: 179 GLMDNLKTVEPKIWVQYIDENHPNNTFNLLHEAAISKNPELLEFILSKKPNINKKSCKGSTALLLAVKSGNAECVRLICKQKGMEIDGQDRKGQTPIDLACRLNMIDIVKILLYYGANPMKSEYDGMCCLHHPIRSNHLEMIKLLLHAKCSPEVKDNNGISPIALAASLGYLEAFYLCIQSLMNSKINIASVINSTDCEGYSCFLNAIRYKQRTIILECLKYGADINLAQNEGKNALHIASEIGWSEIIPKLCDNGININSVDNNLDSALHLGIHNGSLSVAECLLVNHAHVNVCNRNLLTPLLSSANLISQIGVEKSLA-FLKXXXXXXADVKLKDKKKQTILHLLIASGHIETIELL------FQLIKEEEKQFLLNSYDDNGDYPLHVACSNNLRKICNYLISEGANLLLGNYNESLPIHEATRKGHLEIVKDLIDLNIQQITIRNEDEANLIILAVQSGHYNIFEFLYFKDIEMHSKDETGNNILMYACQVGDIGMVKLILKKDFNLQMRNHHQSTPLHQAAQAGQTKMVEYLLSIGAEMYENTFHQTPLTLALDNQHWNTAKVFLNDNNWKNTMEFRFKTGKTHMGYIIMKNEDIANELLNRGLEVISDTNSVNKSL-TKYHFFMLDAGPYDSASVNSRYTEFMTIAKYRKEKLILHPLSNMLLLNKW 2173
G ++ L+ V ++ N +LLH A + + ++L F+L KPNIN + K + LA + G+ E + L+CKQK + ID D KGQT + ++CR +++K+LL GA+ K E D + +HHP+R N LEMI +L VK+NNG +PI +AA GY E F + I + IN+ + ++ D +G C A++ K II CL + DIN Q +GK H AS I + + + ININ DN+L+S LH I N L + + LL A++N+CN++ TP+L + IS + K+L+ +KLL+ AD+ ++D +TI H L+ IE I+++ + I E ++ L+NS D PLH A S +IC L+ GAN + N+ LP+H A KGHL+IVK L++ + + R+ +E++ I +A ++G+Y IF+FL + +KDE G N LM+A + G + +++ +L K+ N+ + + + T LHQAA G ++V+ L + GA + +N F Q+PL +A+ N N K FLND+NW+N M +R G +H+ +I NED+ ELL++ + + + +N ++ + +Y F ++DAGP D AS++ RY ++ +Y++ KL+ HPLS LL KW
Sbjct: 17 GYLNYLEMVPKGFLKDSLNVTDERNGLSLLHYAVLENHLDILSFLLEFKPNINIIALKKVRPIHLASQKGHVEIIELLCKQKSLYIDATDDKGQTALHISCRRGHKEVLKVLLQNGASVHKLESDEISVMHHPVRRNDLEMINILFLYNAPLNVKNNNGQTPIMIAAIEGYAELFSILILKFKENGINVKNALDEKDNDGQCCLSYAVQNKNLDIIKICLDFYVDINTKQADGKTIFHTASIINYPILFKLMKSRDININVGDNDLNSPLHHAIINNKLDMVKVLLKFGANINLCNKDFQTPILLACMEISAL---KNLSGIIKLLIIEKADLNIRDYDMKTIFHYLVVKEKIEMIKVIIYWITYLKNISESQRIELINSQDIVDKSPLHYAVSIGNLEICQVLLEAGANPNIFAANDCLPLHIAAEKGHLDIVKLLLNSSRKSECFRDSNESSAIHIAAENGNYEIFKFLIGIGKDCLAKDEFGRNTLMFAARSGCLPIIEYLLTKETNVNLHDQMKVTALHQAAAEGHLQVVQCLWTSGAILSDNMFGQSPLDIAISNNQENVVKFFLNDDNWQNVMAYRHDNGSSHIENLIKSNEDLTLELLDKCI-IENTSNKMDPNYEVQYRFSLIDAGPDDPASISERYHALKSMTEYKRLKLLRHPLSAKLLKIKW 685 The following BLAST results are available for this feature:
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Transient receptor potential cation channel subfamily A member 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30022407 ID=SMED30022407|Name=Transient receptor potential cation channel subfamily A member 1|organism=Schmidtea mediterranea sexual|type=transcript|length=3197bpback to top protein sequence of SMED30022407-orf-1 >SMED30022407-orf-1 ID=SMED30022407-orf-1|Name=SMED30022407-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1048bp MTEVEVDSNLLTHKHFHLYPFFKFSSRSFSSSKDKEKEKILKSFQRHQVLback to top Annotated Terms
The following terms have been associated with this transcript:
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