Neurogenic locus Notch protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30022402 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: NOTCH1 (notch receptor 1 [Source:HGNC Symbol;Acc:HGNC:7881]) HSP 1 Score: 216.853 bits (551), Expect = 1.143e-56 Identity = 232/772 (30.05%), Postives = 325/772 (42.10%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-DCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC-DKDK---CKCPPGYIGHNCEFNDFCHFISPCEH-NCTTINDNMVCSCLPGYDLMP---DKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C C GW GE C E C HG + R F C C T C C S C G C + C C G+ G C +++ CS +G CEH C+N +F+C+C G+ + + D C+ C T ++ C C G++G C + DEC C C++ I +QC C GFT C + KNG CL+G C C G+ G C +DIDEC + C + +F C C G+T + N +C S+ C +GG C D+D C C G G NCE N SPC+ C D C+C PGY + C C GTC + C+CP+G+ C +++NEC + C +++ + C C G + C+ N TC KD G C C+ G+ G C +INEC + + C++ YKC+C+ L +C+ V + C C +C+ C TGW G+ C+VDI+EC+L+ + +C N++G Y C C + GR+C D C +PC NGG C + + C C PG+ G CEEDINEC ++G C + +Y C CP G+ + C+ +T D C NGG C D C CP GF G C DV+EC PC G C + GS+ C C Y
Sbjct: 321 CVCVNGWTGEDCS----ENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECS---LGANPCEHAGKCINT-LGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCR----HGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHN--GGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCV--NGGTC--KDMTSGYV----CTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL----LPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGY-----SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNG--ANCTDCVDSYTCTCPAGFSGIH----CENNTPDCT-ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQ-PCLH-GGTCQDGCGSYRCTCPQGYT 1052 HSP 2 Score: 187.193 bits (474), Expect = 2.608e-47 Identity = 234/832 (28.12%), Postives = 337/832 (40.50%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTC-----FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL-------------------------------SNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE---DKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN--------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFY----LSTVD----------------------------GRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C+C + G C E C Q+ L C HG + + C+C T NC CS CQNGGTC C C GF G C+ I+ C GN CK +G +C+ V + NC+C W G++C +DVDEC L P CQ C NT G Y C C G+T +G+ + C N CN+ +C +NG IC C SG+ G CS D+DEC + CEH C+N GSF CQC G+T +I+ +C+S C + + +C C PGY G +CE N SPC HN ++ NE +C+CP GF G LC+ D++EC + T C++ C + ++ C C G+ D C P C +G C + C+C+ GY G C+ +INEC S C H C + + +Y C C+ G +C+ C + CD +C C+ G+TG +C+++IDEC N C + ++C C ++ LS V+ G +C N+ C S+PC NGG C + C C+ G++G +C+ +INEC + + C+ G C + Y+C C L+ TC++ +P C NGG CR C CP G+ G C VD++EC +PC + C NT+G + C C + Y
Sbjct: 164 CHCPPSFHGPTCRQDVNE-CGQKPGL-CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCP----GN---------------NCK---------NGGACVDG---------VNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLD-------------------------------KINEFQCECPTGFTGHLCQYDVDECAS-TPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP--------DPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECS--SQPCRHGGTCQDRDNAYLCFCLKG----TTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINEC----ASNPCLNQGTCIDDVAGYKCNC----LLPYTGATCEVVLAPCAPSP-CRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINEC-VLSPC-RHGASCQNTHGGYRCHCQAGY 899 HSP 3 Score: 169.088 bits (427), Expect = 9.590e-42 Identity = 227/840 (27.02%), Postives = 329/840 (39.17%), Query Frame = 1
Query: 1024 CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ-------LDNDGKSCIKEECSKFGTTEVVSGN---CKCKQGWKGKFCNDDVDECLF--------------------------PVCQQ----------------ICVNTIGSYQCSCRE---------------------GFTLLSNGKCAINCL-------------------NNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK-YNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEH--NCTT--INDNMVCSCLPGYDLMP---DKKTCKKLECP-----KCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVH-GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF--------ILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSC-------NLPFYL-----STVDGRSCLEKNDS---------------------CSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKP 3015
C NGG C C C F G +CQ + N C N H+ G ++ C C GF LDN +C+ C GT ++++ C+C GW GK C D C P C+Q C N +GSY+C CR G T G C NNC G C++G+ C C W G+ C+ D+DEC+ + C++ C N G +NC C +G+T + + + I + C +G C C+CP G G C ND C +PC NC T +N +C+C GY D C P KC+ T +C+C +G+ G CE D+NEC++ CQ+ C + IG F C C G++ + N C C+H G+C + +C C +G+ G C D++EC C++ +Y C C G+ I + C CK+G F C C+ G+TG C+ +I+EC + C+H C + + +Y C C N L S D +CL+K D +PC NGG C + C+C GY+ +C ++NEC H G CR++ Y+C C PG+ C I+ + NP C+NGG C+DM+ C C GF G +C +++EC PC +G C + + C C +L Y G +C E VL P
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDN---ACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGE-DCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDAC-ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCIN-TLGSFECQCLQGYTGPRCEIDVNECVSNP-CQNDATCLDQIGEFQCICMPGYEGVHCEV-----NTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHY--GSCKDGVATFT--CLCRPGYTGHHCETNINEC--SSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVH---GACRDSLNGYKCDCDPGW----SGTNCDINNNECESNP-CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN-PCLN-QGTCIDDVAGYKCNC----LLPYTGATC----EVVLAP 832 HSP 4 Score: 166.007 bits (419), Expect = 8.429e-41 Identity = 223/804 (27.74%), Postives = 328/804 (40.80%), Query Frame = 1
Query: 781 IDNCVPDCGEHGIC----VKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNR-TCEHICVNEGENNFQCKCQSGFQLD---NDGKSCIKEECSKFGTTEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN-----GDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGF---TLQINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGT-----CNENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQ--------SVCSLCKNGK--CDFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHG----CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR-----CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICY---NTYGSFYCQCSSNY 2958
ID C PD +G C C C G+ G C E Q C HG + R + C C T NC + L C+ + GTC C C G+ G C + I+ C+ N TCE +G N F C+C G+ ++ C C + ++G C C GW G C+ + +EC C C + Y C+CREGF S C N +N C N G C++ + C C + G C + + C + +G E SF+C C +G+ T +++ +C+ C C N GG +C C GY G NCE + D C +PC + +CT + C CLPG+ ++ + C G + C CP GF+G+ CEN+ +C + C + I SF C C G + + + + CL C + +C C GY G C ++ C C T Y+C C G+ S SC+ V LC++G D N C+C+ G+TG C+ +DEC + + C + G YSC C ++ G +C E+ D C S PC+NGG C++ KC C G G CE ++++C P+ C G C + G Y C CPPG++ + C+ + + NP C G + R C C G G C ++ C + PC K G C NT F C+C + +
Sbjct: 567 IDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQP----CRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCE-----DGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGF---SGPNCQTN-INECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGY----RCHCQAGYSGRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYH-----GVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV----GERCEGDVNECLSNP-CDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGC-KGKPC-KNGGTCAVASNTARGFICKCPAGF 1340 HSP 5 Score: 155.992 bits (393), Expect = 1.339e-37 Identity = 213/739 (28.82%), Postives = 301/739 (40.73%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKC---QSGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQT---------ICQH--VCTNTIGSFFCRCKNGHKLA--ED-KRSCIPP---NKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQS-VCSLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDT-MCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGV 2859
CVHG D + C C + NC + C S C NGGTC C C EGF G CQ IN C+ + C+N+G ++C C +G + C C G + + S +C C GW+G+ C D++EC+ C+ C NT G Y+C C+ G++ + +C N C+ G C +GI C C G+ G C DI+EC + +G C + S+ C C +GF+ + N C SC NGG C + C CPPG+ G C+ + PC H T + + C+C GY + + C G T + +C+CP G+ GL C+ C +CQH +C + + CRC+ G+ + ED C P N TC D C C +GY G C E+I+EC SH C++ C++ +YKCSC G N C V + ++ KC FNN C C G+ GE C+ D++ECL N + NCV + C C + GR C + C PCKNGG C + CKC G+ G +CE D C +G G C + + C+C L CQ + C N G C S RC CP F+G+ C +
Sbjct: 725 CVHGACRDSLN-GYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGAN--CTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC----FNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDY------LGGYSCKCVAGYHGVNCSEEIDEC--LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKC-FNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECR-----AGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNG--GTCISGPRSPTCLC----LGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1427 HSP 6 Score: 87.8113 bits (216), Expect = 9.800e-17 Identity = 102/351 (29.06%), Postives = 141/351 (40.17%), Query Frame = 1
Query: 2086 KTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECK----KYSHICEHFCMNTEGSYKCSCMPGFI----LSANSHSCQSVCSLCKN-GKCDF----NNKCKCKTGWTGE-------------------------------------LCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKC-----VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPP---GYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQC 2946
+TCL+ C+C + G RC +D N C K + C Y CSC GF L+ ++C + + C+N G CD KC+C GW+G+ C D++EC C+H C N GSY C C +T G +C CS SPC+NGG C V +C C PG+ G +CEE+I++C K+G G C + Y C CPP G +D CQ+ C NGG C + C C G+ G DC ++D+C A C C++ SFYC+C
Sbjct: 29 ETCLNGGKCEAANGTEACVCGGAFVGPRC-QDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNAC--LTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCR-----ATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNG--GACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPN------ACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAA-CFH-GATCHDRVASFYCEC 361 HSP 7 Score: 67.0106 bits (162), Expect = 2.059e-10 Identity = 63/205 (30.73%), Postives = 86/205 (41.95%), Query Frame = 1
Query: 2401 ECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC--------VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRN-------TFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
E LN KC+ +NG+ +C C F G C + N S+PCKN G C + C C G++G C P+ CRN T Y+C CPPG+ K+CQ + D + C NGG C C+CP FHG C DV+EC + + G C+N GS+ C C + +
Sbjct: 29 ETCLNGGKCE----AANGTEACVCGGAFV-----GPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT-------PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW----SGKSCQQA--DPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHT 211
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: NOTCH3 (notch receptor 3 [Source:HGNC Symbol;Acc:HGNC:7883]) HSP 1 Score: 208.764 bits (530), Expect = 2.169e-54 Identity = 236/842 (28.03%), Postives = 344/842 (40.86%), Query Frame = 1
Query: 808 EH-GICVKSR----CYCETGWFGERCVILEPELCKQ--RKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ---LDNDGKSCIKEECSKFGTTE-VVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN----GDCLNGI----CYCFSGWHGEDCSLDIDECKYN--------------------------------HGCEH------LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIE-CLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNM-VCSCLPGY-DLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGH---KLAEDKRSCIPP---NKKTCLDKDCVHGQCFNS-KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-------CKTGWTGELCDVDIDEC--------LLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCV----NSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD------TMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYA-PCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTM 2994
EH G CV ++ C C G+ G RC E R C+ R F+CIC T C +++ C S C NGG C C C GF G CQL+++ C+ N CV++ + ++C+C GF+ D + C + C + + S +C C G+ G C VDEC C+ C++ + Y C C G T + C +N +++C N G C +GI C C G+ G C+++I+EC + H C H +C + PG F C C G++ + +C + C GG C D C CPPG G CE C +PCEH C + + VCSC G+ D + +C+ C C GFAG C D++ECL+ CT+ + SF C C G+ +D C P N TC+D NS C+C+ GY G C + + C + C ++C+C+ F CQ++ C C +C C GW+G LCD+ C + + CQ CV+ + S+ C C G C ++ D C + PC++GG C C+C PGYNGD+CE+D++EC +HG G C + Y C CPPG L + C+I+ D P CL+ G C D+ RC CP G+ G+ C D++EC+ A R + G F C C + + G C T+
Sbjct: 402 EHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCL------DRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGA---KCVDQ-PDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGV---NCEVN-IDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPC-TPNPCEHGGRCESAPGQLPVCSCPQGWQDPCLNGGSCQD---------GVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDG-------VNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFT----GPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCP-----EGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHG--GSCIDLVARYLCSCPPGTLGV----LCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAG----FSGPRCQTV 1193 HSP 2 Score: 175.637 bits (444), Expect = 5.140e-44 Identity = 236/899 (26.25%), Postives = 342/899 (38.04%), Query Frame = 1
Query: 823 VKSRCYCETGWFGERCVILEPELCKQRKLLFCVHG--CSFDKRKLDFSCICGIKETQNNCL-ELRTCSKG--CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLLS-------------------------------NGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFT---LQINKKKCISKSC----------------------------------NIECLNGGLCDKDK-----CKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILS---ANSHSCQSVCSLCKNGKC---DFNNKCKCKTGWTGELCDVDI--DECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNS------------------------------KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP-HCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGR 3036
+ C C G+ G C + +P L C HG CS F C C +C ++ C G C++GGTC RCQC G+ G C+ C+ N C G+ + C C GF+ N + C C GT V + NC+C W G+FC +DVDEC L P C C NT+G + C C G+T S GK + C N C+++ C +NG IC C G+ G C D+DEC + CEHL CVN GSF CQC G+T + + +C+S C + C+NGG+C KD+ C CP G+ G C+ + +PC + C D C C G++ + C G C + C C G+ G CE+ ++EC +Q C+H C + + + CRC +G + N C C G C + C+C+ G+ G C+ +INEC C++ E ++C C PG + SH C C +G C +C C+ GW+G C + D C + C + + C+C V GR C + +PC++GG+C ++ C C PG+ G C D++EC +S G C + ++ C CPPGY C+ D C+P C NGG C D C C G+ G C + D C PC G+C + F C C ++ G C T+ + + + GR
Sbjct: 101 ARFSCRCPRGFRGPDCSLPDPCLSSP-----CAHGARCSVGPDGR-FLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGG---TCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVC-KDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP-CRHGGKCLDLVDKYLCRCPSGTTGVNCEV-----NIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAH--EPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCP-----PGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQDPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC---LSNPCGPGTCTDHVASFTCTCPPGYGGFH----CEQDLPD--CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR-PC-LHGGVCSAAHPGFRCTCLESFT----GPQCQTLVDWCSRQPCQNGGR 961 HSP 3 Score: 159.458 bits (402), Expect = 5.988e-39 Identity = 180/664 (27.11%), Postives = 277/664 (41.72%), Query Frame = 1
Query: 1216 DGKSCIKE-ECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFP------VCQQICVNTIGSYQCSCREGFTLLSNGKCAIN--CLNN-CNKNGDCLNG-----ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD-----KCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN--DNMVCSCLP---GYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHK--LAEDKRSCI--PPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHF--CMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLS----------------------TVDGRSC------------LEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
DG C C++ + E C C GW G+ C + D C VCQ V + C C GF C++ CL++ C C G +C C G+ G C D+DEC+ C H C+N PGSF CQC +G+T + + + + C NGG C + C C PG+ G NCE N D C C + T ++ + C C P G D C+ L+ C G T + C C G+ G C +I++C +C H C + + SF+C C G L +C+ P ++ D + V+G+ + C C G+ G CD+D++EC ++ CEH C+NT+GS+ C +C G+TG C+ D++ECL + Q C++ G ++C C F + V+G SC L+ ++ S+PC+NG KCV+ +C+C G+ G C+ ++++C H G C + ++ C C PGY C+ + P C +GG C D+ C CP G G++C V++D+C PC G+C + + C C +
Sbjct: 44 DGSPCANGGRCTQLPSREAA---CLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGF---RGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCA-PSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR-CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQ-LQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCAT-AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGR---AICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLC---------------------------------QCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHH---GRCVDGIASFSCACAPGYT----GTRCESQVDECRSQP-CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASN-PC--TFGVCRDGINRYDCVCQPGFT 649 HSP 4 Score: 129.028 bits (323), Expect = 1.548e-29 Identity = 187/721 (25.94%), Postives = 263/721 (36.48%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLD---NDGKSCIKEECSKFGTTEVVSG-NCKCKQGWKGKFCNDDV--DECLFPVCQQ--ICVNTIGSYQCSCREGFT-----LLS---------NGKC------------AINCLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQC---HSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKT----CKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLN---------QTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPG---FILSANSHSCQSVCSLCKNGKCDFNN---------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFG 2688
+D+C PD HG CV C C G+ G RC E C+ + C HG + C C T NC + + C+ G C G C C GF G C +EIN C+ G E +GEN F+C C G C E CS + G C C+ GW G C+ + D C C+ C + + C+C G LLS G+C + C G C +G+ C C G+ G C+ D+DEC N C + SF C C + GF + + C SC NGG C + C C PGY G +C+ PC H C+ + C+CL + P +T C + C R C CP G++G LC+ C + +CQ C + S +C C G + ++ P + C G C C GY G C++D++EC S C+H C++ Y CSC PG + N C L +C N +C C G+TG C+ DI+EC H R CL+ GG +C C G++G C+ ++ C+ +HG G+CR + G
Sbjct: 545 VDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDE-CRSQP---CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCG----EGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQDPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSC----FNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESF-TGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECA--SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHT-----------------------RDCLQD--------PGGGF----RCLCHAGFSGPRCQTVLSPCESQPCQHG--GQCRPSPG 1213 HSP 5 Score: 107.457 bits (267), Expect = 8.095e-23 Identity = 158/598 (26.42%), Postives = 225/598 (37.63%), Query Frame = 1
Query: 808 EHGICVKS----RCYCETGWFGERCV-ILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKG-CQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVN-----EGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGTTE-VVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIE------CLNGGLC-DKDK---CKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYD---LMPDKKTCKKLECPKCVRGTC----NENKCKCPKGFAGLLCENDINECL------NQTICQH--VCTNTIGSFFCRCKNGH---KLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSH--------SCQSVCSLCKNGKCDF---------NNKCKCKTGWTGELC 2385
HGIC + RC CE GW G RC L + C+ + C G + + F C C C L C+ C++GG RC+ G QL + SC +G + C+N +G +F C C GF + D C+ C T+ V S C C G+ G C D+ +C C CV+ + S+ C CR G+T A CL+ C G C C C + G C +D C C++ V C C G++ + I C + I C GG C D+D C CP G G +CE PC+H C +C CLPGY+ D C C G+C C CP G G+LCE + ++C + C H C + +G F C C G+ + D C +DC+ +C+C +G+ G RC ++ C+ S C+H G + S PG L+ H C+ V C+ +C +C C G +G C
Sbjct: 704 SHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQP---CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGG-----RCESAPG------QLPVCSCPQGW------QDPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQP-CQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQH--GGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCE--SQPCQH-----GGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSC 1271 HSP 6 Score: 82.8037 bits (203), Expect = 2.419e-15 Identity = 121/435 (27.82%), Postives = 172/435 (39.54%), Query Frame = 1
Query: 781 IDNCVPD-CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRT-CSK-GCQNGGTCFQ--GRCQCTEGFEGDQCQLEINSC--SRGQMGNRTCEHICVNEGE-----NNFQCKC---QSGFQLDNDGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREG----FTLLSNGKCA----INCLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN--HGCEHL-CVNVPGS-FNCQCHSGFT---LQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCV--RGTCNENKCKCPKGFAGLLCEN 1953
+ +C P C G CV C C G+ G C E + C R C+HG F C C T C L CS+ CQNGG C Q C C G+ G C + C + Q+G R E +C G+ ++ C C ++G + + C+ + C GT G C+C G+ G C DDVDEC CQ C++ + Y CSC G ++ C ++ C NG C++ + C C G+ G C DI+EC+ H C+ PG F C CH+GF+ Q C S+ C +GG +C+ PG G CH P G ++C++L+CP V + T +C CP G +G C +
Sbjct: 872 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ-HEADPCLSRP---CLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRL-EQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQ----HGG-----QCRPSPGPGGG---LTFTCHCAQP----------------FWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRS 1273
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: TNXB (tenascin XB [Source:HGNC Symbol;Acc:HGNC:11976]) HSP 1 Score: 205.682 bits (522), Expect = 4.739e-53 Identity = 187/704 (26.56%), Postives = 269/704 (38.21%), Query Frame = 1
Query: 799 DCGEHGICVKSRCYCETGWFGERCVILE-PELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ-QICVNTIGSYQCSCREGFTLLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDI--DECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECP-KCV-RGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAED--KRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCD--EDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGEC--RNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDV 2865
DC + G CV+ RC C G+ G C P C+ R CV G C+C + +C + R+C +GC G C GRC C G+ GD C + SC RG CE N +C C G+ ++ G CS+ G + G C C G+ G+ C C + + CV+ +C C G+T C+ C +C G C +G C C +G+ G+DC + +C CE C C G+T C S++C +C G C+ C C GY G +C + C +C ++ C C PGY + C CP C RG C + +C C GF G C + C +C + + C C G+ ED RSC C + GQC + +C+C+ GY G+ C + N+C ++ + C+ EG C + +C S C G+C+ +C C G+TG C + C + C+ G+CV C C GY G+ C ++ + P S C G C R +C+C G+ D C I T C C G C D S C C G+ G DCG +V
Sbjct: 190 DCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGR--CVQGV----------CVCRAGFSGPDCSQ-RSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMR--SCPRGCSQRGRCE---------NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCK--DGRCVCDPGYTGEDCG--TRSCPWDCGEGGRCVDG----RCVCWPGYT---GEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCE--------DGRCVCWPGYT----GTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-------VRSCPGDCRGRGRCESGRCMCWPGY----TGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS--RRCPGDCRGHGLCEDGV----CVCDAGYS-GEDCSTRSC----PGGCRGR----GQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDC--------SIRTCPSNCH--GRGRCE-EGRCLCDPGYTGPTCATRM---------------------------------------------CPADCRGRGRCVQGVCLCHVGYGGEDCGQE----EPPAS--ACPGGCGPRELCRAGQCVCVEGFRGPD----CAIQT----CPGDCRGRGECHDGS-CVCKDGYAGEDCGEEV 749 HSP 2 Score: 191.815 bits (486), Expect = 9.164e-49 Identity = 165/627 (26.32%), Postives = 246/627 (39.23%), Query Frame = 1
Query: 787 NCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-NNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNT--IGSYQCSCREGFTLLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDI--DECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVRG--TCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSH---ICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDI 2625
+C DC G CV+ C C G+ G P+ C QR C GCS R C+C T ++C +R+C +GC G C GRC C G+ G+ C G R+C C G + +C C G+ ++ G +C + G V G C C G+ G ++C C + C +C C G+ S C + +C +CN+ G C +G C C+ G+ G DC +C+ CE+ C C++G++ + C +SC +C G C+ +C C PGY G +C C +C + C C PG+ + C CP RG C + C C G++G +C ++ C C +C +G + ED S + C + HG C + CIC GY + C I C H CE EG +C C PG+ + + C + C G+C C C G+ GE C + C + G C C + G C + +C C+ G+C + C CK GY G+ C E++
Sbjct: 217 SCPGDCQGRGRCVQGVCVCRAGFSG-------PD-CSQRS---CPRGCSQRGRCEGGRCVCDPGYTGDDC-GMRSCPRGCSQRGRCENGRCVCNPGYTGEDC------------GVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGG--RCVDGRCVCWPGYTG-------EDCSTRTCPRDCRGRGRCEDGECICDTGY---SGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGV--------CVCNAGYS----GEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCG-------TRACPGDCRGRGRCVDGRCVCNPGFT----GEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSG-------EDCSTRS-CPGGCRGR-----GQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCS--IRTCPSNCHGRGRCE------EG--RCLCDPGYTGPTCATRMCPADCR--GRGRC-VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQ--CVC-----VEGFRGPDCAIQ--TCPGDCRGRGECHDGSCVCKDGYAGEDCGEEV 749 HSP 3 Score: 174.866 bits (442), Expect = 2.094e-43 Identity = 161/607 (26.52%), Postives = 230/607 (37.89%), Query Frame = 1
Query: 1219 GKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPK--CVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFC--RCKNGHKLAEDKRSCIPP------NKKTCLDKDCV-HGQCFNSKCICKSGYRG-----KRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNL-PFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYE---CICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDV--DECQRYAPCDKLRGICYNTYGSFYCQ---CSSN 2955
G++ ++ CS G ++ C C+ GW G C+D D + S + +C ++CN G C+ G C CF G+ G C C + CV C C +GF+ C +SC C G C+ +C C PGY G +C + C C+ +N C C PGY + C CP+ RG C + +C C G+ G C G+ C C G + + + C P + +TC +DC G+C + +CIC +GY G + C D N+ + CE +C C PG+ S +C C G+C+ N C C G++GE C V C +C S C P Y GR C + +C C+ G+CV+ +C C PG+ G+ C C G+CR G E C+C GY D ST+ C C G C D RC C G+ G DCGV ++C ++ C IC+ Y S C C SN
Sbjct: 135 GQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEI-----------------------PPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWP--SCPGDCQGRGRCVQGV----CVCRAGFS----GPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG-------MRSCPRGCSQRGRCENGRCVCNPGYT----GEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDC---------------------GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC-PRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGR----CE--------DGRCVCWPGYTGTDCGSRACPRDCR--GRGRCE-NGVCVCNAGYSGEDCGV---------RSCPGDCRGRGRCESGRCMCWPGY----TGRDCGTR--ACPGDCRGRGRCVDGRCVCNPGFTGEDC-----------GSRRCPGDCRG-HGLCEDGVCVCDAGYSGED------CSTRS--CPGGCRGRGQCLD-GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSN 624 HSP 4 Score: 101.679 bits (252), Expect = 6.250e-21 Identity = 89/295 (30.17%), Postives = 116/295 (39.32%), Query Frame = 1
Query: 2104 DCV-HGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMN---TEGSYKCSCMPGFILS-ANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYS--CSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGEC--RNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCD-KLRGICYNTYGSFYCQCSSNY 2958
DC G+C C+C++G+ G C + C C EG +C C PG+ SC CS + G+C+ N +C C G+TGE C V C C C C+ P Y G C + SC C GG+CV+ +C C PGY G+ C S C +C R + ECIC GY D C + + C C G C D RC C G+ G DCG R P D + RG C N C C++ Y
Sbjct: 221 DCQGRGRCVQGVCVCRAGFSGPDCSQ---------RSCPRGCSQRGRCEGG-RCVCDPGYTGDDCGMRSCPRGCS--QRGRCE-NGRCVCNPGYTGEDCGV---------RSCPRGCSQRGRCKDGRCVCD-PGY----TGEDCGTR--SCPWDCGEGGRCVDGRCVCWPGYTGEDC-----------STRTCPRDCRGRGRCEDGECICDTGYSGDD----CGVRS----CPGDCNQRGRCED-GRCVCWPGYTGTDCG------SRACPRDCRGRGRCENG----VCVCNAGY 456
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: TNXB (tenascin XB [Source:HGNC Symbol;Acc:HGNC:11976]) HSP 1 Score: 204.142 bits (518), Expect = 1.301e-52 Identity = 187/704 (26.56%), Postives = 269/704 (38.21%), Query Frame = 1
Query: 799 DCGEHGICVKSRCYCETGWFGERCVILE-PELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ-QICVNTIGSYQCSCREGFTLLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDI--DECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECP-KCV-RGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAED--KRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCD--EDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGEC--RNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDV 2865
DC + G CV+ RC C G+ G C P C+ R CV G C+C + +C + R+C +GC G C GRC C G+ GD C + SC RG CE N +C C G+ ++ G CS+ G + G C C G+ G+ C C + + CV+ +C C G+T C+ C +C G C +G C C +G+ G+DC + +C CE C C G+T C S++C +C G C+ C C GY G +C + C +C ++ C C PGY + C CP C RG C + +C C GF G C + C +C + + C C G+ ED RSC C + GQC + +C+C+ GY G+ C + N+C ++ + C+ EG C + +C S C G+C+ +C C G+TG C + C + C+ G+CV C C GY G+ C ++ + P S C G C R +C+C G+ D C I T C C G C D S C C G+ G DCG +V
Sbjct: 190 DCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGR--CVQGV----------CVCRAGFSGPDCSQ-RSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMR--SCPRGCSQRGRCE---------NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCK--DGRCVCDPGYTGEDCG--TRSCPWDCGEGGRCVDG----RCVCWPGYT---GEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCE--------DGRCVCWPGYT----GTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-------VRSCPGDCRGRGRCESGRCMCWPGY----TGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS--RRCPGDCRGHGLCEDGV----CVCDAGYS-GEDCSTRSC----PGGCRGR----GQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDC--------SIRTCPSNCH--GRGRCE-EGRCLCDPGYTGPTCATRM---------------------------------------------CPADCRGRGRCVQGVCLCHVGYGGEDCGQE----EPPAS--ACPGGCGPRELCRAGQCVCVEGFRGPD----CAIQT----CPGDCRGRGECHDGS-CVCKDGYAGEDCGEEV 749 HSP 2 Score: 191.045 bits (484), Expect = 1.993e-48 Identity = 166/627 (26.48%), Postives = 246/627 (39.23%), Query Frame = 1
Query: 787 NCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-NNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNT--IGSYQCSCREGFTLLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDI--DECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVRG--TCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSH---ICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDI 2625
+C DC G CV+ C C G+ G P+ C QR C GCS R C+C T ++C +R+C +GC G C GRC C G+ G+ C G R+C C G + +C C G+ ++ G +C + G V G C C G+ G ++C C + C +C C G+ S C + +C +CN+ G C +G C C+ G+ G DC +C+ CE+ C C++G++ + C +SC +C G C+ +C C PGY G +C C +C + C C PG+ + C CP RG C + C C G++G +C ++ C C +C +G + ED S + C + HG C + CIC GY + C I C H CE EG +C C PG+ + + C + C G+C C C G+ GE C + C + G C C F G C + +C C+ G+C + C CK GY G+ C E++
Sbjct: 217 SCPGDCQGRGRCVQGVCVCRAGFSG-------PD-CSQRS---CPRGCSQRGRCEGGRCVCDPGYTGDDC-GMRSCPRGCSQRGRCENGRCVCNPGYTGEDC------------GVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGG--RCVDGRCVCWPGYTG-------EDCSTRTCPRDCRGRGRCEDGECICDTGY---SGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGV--------CVCNAGYS----GEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCG-------TRACPGDCRGRGRCVDGRCVCNPGFT----GEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSG-------EDCSTRS-CPGGCRGR-----GQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCS--IRTCPSNCHGRGRCE------EG--RCLCDPGYTGPTCATRMCPADCR--GRGRC-VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQ--CVCVEGF-----RGPDCAIQ--TCPGDCRGRGECHDGSCVCKDGYAGEDCGEEV 749 HSP 3 Score: 173.326 bits (438), Expect = 5.472e-43 Identity = 159/606 (26.24%), Postives = 228/606 (37.62%), Query Frame = 1
Query: 1219 GKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPK--CVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFC--RCKNGHKLAEDKRSCIPP------NKKTCLDKDCV-HGQCFNSKCICKSGYRG-----KRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYE---CICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDV--DECQRYAPCDKLRGICYNTYGSFYCQ---CSSN 2955
G++ ++ CS G ++ C C+ GW G C+D D + S + +C ++CN G C+ G C CF G+ G C C + CV C C +GF+ C +SC C G C+ +C C PGY G +C + C C+ +N C C PGY + C CP+ RG C + +C C G+ G C G+ C C G + + + C P + +TC +DC G+C + +CIC +GY G + C D N+ + CE +C C PG+ S +C C G+C+ N C C G++GE C V C +C G C GR C + +C C+ G+CV+ +C C PG+ G+ C C G+CR G E C+C GY D ST+ C C G C D RC C G+ G DCGV ++C ++ C IC+ Y S C C SN
Sbjct: 135 GQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEI-----------------------PPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWP--SCPGDCQGRGRCVQGV----CVCRAGFS----GPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG-------MRSCPRGCSQRGRCENGRCVCNPGYT----GEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDC---------------------GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC-PRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGR----CE--------DGRCVCWPGYTGTDCGSRACPRDCR--GRGRCE-NGVCVCNAGYSGEDCGV---------RSCPGDC---RGRGRCESGRCMCWPGYTGRDCGTR--ACPGDCRGRGRCVDGRCVCNPGFTGEDC-----------GSRRCPGDCRG-HGLCEDGVCVCDAGYSGED------CSTRS--CPGGCRGRGQCLD-GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSN 624 HSP 4 Score: 100.908 bits (250), Expect = 1.041e-20 Identity = 89/295 (30.17%), Postives = 116/295 (39.32%), Query Frame = 1
Query: 2104 DCV-HGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMN---TEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYS--CSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGEC--RNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCD-KLRGICYNTYGSFYCQCSSNY 2958
DC G+C C+C++G+ G C + C C EG +C C PG+ SC CS + G+C+ N +C C G+TGE C V C C C C+ P Y G C + SC C GG+CV+ +C C PGY G+ C S C +C R + ECIC GY D C + + C C G C D RC C G+ G DCG R P D + RG C N C C++ Y
Sbjct: 221 DCQGRGRCVQGVCVCRAGFSGPDCSQ---------RSCPRGCSQRGRCEGG-RCVCDPGYTGDDCGMRSCPRGCS--QRGRCE-NGRCVCNPGYTGEDCGV---------RSCPRGCSQRGRCKDGRCVCD-PGY----TGEDCGTR--SCPWDCGEGGRCVDGRCVCWPGYTGEDC-----------STRTCPRDCRGRGRCEDGECICDTGYSGDD----CGVRS----CPGDCNQRGRCED-GRCVCWPGYTGTDCG------SRACPRDCRGRGRCENG----VCVCNAGY 456
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: TNXB (tenascin XB [Source:HGNC Symbol;Acc:HGNC:11976]) HSP 1 Score: 204.142 bits (518), Expect = 1.301e-52 Identity = 187/704 (26.56%), Postives = 269/704 (38.21%), Query Frame = 1
Query: 799 DCGEHGICVKSRCYCETGWFGERCVILE-PELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ-QICVNTIGSYQCSCREGFTLLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDI--DECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECP-KCV-RGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAED--KRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCD--EDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGEC--RNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDV 2865
DC + G CV+ RC C G+ G C P C+ R CV G C+C + +C + R+C +GC G C GRC C G+ GD C + SC RG CE N +C C G+ ++ G CS+ G + G C C G+ G+ C C + + CV+ +C C G+T C+ C +C G C +G C C +G+ G+DC + +C CE C C G+T C S++C +C G C+ C C GY G +C + C +C ++ C C PGY + C CP C RG C + +C C GF G C + C +C + + C C G+ ED RSC C + GQC + +C+C+ GY G+ C + N+C ++ + C+ EG C + +C S C G+C+ +C C G+TG C + C + C+ G+CV C C GY G+ C ++ + P S C G C R +C+C G+ D C I T C C G C D S C C G+ G DCG +V
Sbjct: 190 DCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGR--CVQGV----------CVCRAGFSGPDCSQ-RSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMR--SCPRGCSQRGRCE---------NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCK--DGRCVCDPGYTGEDCG--TRSCPWDCGEGGRCVDG----RCVCWPGYT---GEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCE--------DGRCVCWPGYT----GTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCG-------VRSCPGDCRGRGRCESGRCMCWPGY----TGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGS--RRCPGDCRGHGLCEDGV----CVCDAGYS-GEDCSTRSC----PGGCRGR----GQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDC--------SIRTCPSNCH--GRGRCE-EGRCLCDPGYTGPTCATRM---------------------------------------------CPADCRGRGRCVQGVCLCHVGYGGEDCGQE----EPPAS--ACPGGCGPRELCRAGQCVCVEGFRGPD----CAIQT----CPGDCRGRGECHDGS-CVCKDGYAGEDCGEEV 749 HSP 2 Score: 191.045 bits (484), Expect = 1.994e-48 Identity = 166/627 (26.48%), Postives = 246/627 (39.23%), Query Frame = 1
Query: 787 NCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-NNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNT--IGSYQCSCREGFTLLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDI--DECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVRG--TCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSH---ICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDI 2625
+C DC G CV+ C C G+ G P+ C QR C GCS R C+C T ++C +R+C +GC G C GRC C G+ G+ C G R+C C G + +C C G+ ++ G +C + G V G C C G+ G ++C C + C +C C G+ S C + +C +CN+ G C +G C C+ G+ G DC +C+ CE+ C C++G++ + C +SC +C G C+ +C C PGY G +C C +C + C C PG+ + C CP RG C + C C G++G +C ++ C C +C +G + ED S + C + HG C + CIC GY + C I C H CE EG +C C PG+ + + C + C G+C C C G+ GE C + C + G C C F G C + +C C+ G+C + C CK GY G+ C E++
Sbjct: 217 SCPGDCQGRGRCVQGVCVCRAGFSG-------PD-CSQRS---CPRGCSQRGRCEGGRCVCDPGYTGDDC-GMRSCPRGCSQRGRCENGRCVCNPGYTGEDC------------GVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGG--RCVDGRCVCWPGYTG-------EDCSTRTCPRDCRGRGRCEDGECICDTGY---SGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGV--------CVCNAGYS----GEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCG-------TRACPGDCRGRGRCVDGRCVCNPGFT----GEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSG-------EDCSTRS-CPGGCRGR-----GQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCS--IRTCPSNCHGRGRCE------EG--RCLCDPGYTGPTCATRMCPADCR--GRGRC-VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQ--CVCVEGF-----RGPDCAIQ--TCPGDCRGRGECHDGSCVCKDGYAGEDCGEEV 749 HSP 3 Score: 173.326 bits (438), Expect = 5.472e-43 Identity = 159/606 (26.24%), Postives = 228/606 (37.62%), Query Frame = 1
Query: 1219 GKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPK--CVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFC--RCKNGHKLAEDKRSCIPP------NKKTCLDKDCV-HGQCFNSKCICKSGYRG-----KRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYE---CICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDV--DECQRYAPCDKLRGICYNTYGSFYCQ---CSSN 2955
G++ ++ CS G ++ C C+ GW G C+D D + S + +C ++CN G C+ G C CF G+ G C C + CV C C +GF+ C +SC C G C+ +C C PGY G +C + C C+ +N C C PGY + C CP+ RG C + +C C G+ G C G+ C C G + + + C P + +TC +DC G+C + +CIC +GY G + C D N+ + CE +C C PG+ S +C C G+C+ N C C G++GE C V C +C G C GR C + +C C+ G+CV+ +C C PG+ G+ C C G+CR G E C+C GY D ST+ C C G C D RC C G+ G DCGV ++C ++ C IC+ Y S C C SN
Sbjct: 135 GQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEI-----------------------PPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWP--SCPGDCQGRGRCVQGV----CVCRAGFS----GPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG-------MRSCPRGCSQRGRCENGRCVCNPGYT----GEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDC---------------------GTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTC-PRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGR----CE--------DGRCVCWPGYTGTDCGSRACPRDCR--GRGRCE-NGVCVCNAGYSGEDCGV---------RSCPGDC---RGRGRCESGRCMCWPGYTGRDCGTR--ACPGDCRGRGRCVDGRCVCNPGFTGEDC-----------GSRRCPGDCRG-HGLCEDGVCVCDAGYSGED------CSTRS--CPGGCRGRGQCLD-GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSN 624 HSP 4 Score: 100.908 bits (250), Expect = 1.041e-20 Identity = 89/295 (30.17%), Postives = 116/295 (39.32%), Query Frame = 1
Query: 2104 DCV-HGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMN---TEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYS--CSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGEC--RNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCD-KLRGICYNTYGSFYCQCSSNY 2958
DC G+C C+C++G+ G C + C C EG +C C PG+ SC CS + G+C+ N +C C G+TGE C V C C C C+ P Y G C + SC C GG+CV+ +C C PGY G+ C S C +C R + ECIC GY D C + + C C G C D RC C G+ G DCG R P D + RG C N C C++ Y
Sbjct: 221 DCQGRGRCVQGVCVCRAGFSGPDCSQ---------RSCPRGCSQRGRCEGG-RCVCDPGYTGDDCGMRSCPRGCS--QRGRCE-NGRCVCNPGYTGEDCGV---------RSCPRGCSQRGRCKDGRCVCD-PGY----TGEDCGTR--SCPWDCGEGGRCVDGRCVCWPGYTGEDC-----------STRTCPRDCRGRGRCEDGECICDTGYSGDD----CGVRS----CPGDCNQRGRCED-GRCVCWPGYTGTDCG------SRACPRDCRGRGRCENG----VCVCNAGY 456
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Match: Y64G10A.7 (pep chromosome:WBcel235:IV:14291901:14319564:1 gene:WBGene00013416.1 transcript:Y64G10A.7e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y64G10A.7) HSP 1 Score: 154.066 bits (388), Expect = 1.521e-37 Identity = 176/601 (29.28%), Postives = 242/601 (40.27%), Query Frame = 1
Query: 1282 CKCKQGWKGKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKY-NHGCEHLCVNVPGSFNCQCHSGFTLQINKKKC--------ISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPC-------EHNCTTINDNMVCSCLPGYDLMPDKKTCKKL-ECPKC---------VRGTCNENKCKCPKGFA----GLLCENDINEC-LNQTICQHVCTNTI-GSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFN----SKCICKSGYR---GKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-------------------SPCKNGGKC------VNSKCKCKPGYNGDSCEEDINECQWPIS-KHGCIGE-CRNTFGNYEC---------ICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDC 2853
C+C G+ G C D +EC+ C+ CVNTIG+Y C C GF L +G N C+ DIDEC N GC CVN PG F C C S L + + C + C EC N + +C+C G+ E C + PC +H+CT + C C PG+ L D+++C + EC K V+GT +CKC +G+ G CE + C + CQH C + G C+C+NG+ LA D++ C N+ + DC C N +C CK G+R ++ EDI+EC + CE C N EG Y CSC PGF LS + HSC D++ECL+N C C N GS C C Y+ D +SC+ +DS S C+NGGKC + SKC C GY G+ CE+ W + H C + C + G+ C CP G+ C++ + C+P C CP G +G C
Sbjct: 141 CECPVGFTGAKCQYDANECMANNGGCEHECVNTIGTYYCRCWPGFELSGDG-------NTCS-----------------------DIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLS--ENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGT---YRCKCREGYQLGRDGRTCEEMLGGCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECHENNGDCSQ-ICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCH------------------------------DMNECLINNGGCAQLCKNRKGSRRCQC-FAGYILAHDEKSCVAASDSADIFSNECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLKCRMDCPNGRCDPV---------FGYCTCPDGLYGQSC 665 HSP 2 Score: 142.895 bits (359), Expect = 3.449e-34 Identity = 219/765 (28.63%), Postives = 292/765 (38.17%), Query Frame = 1
Query: 1024 CQNGGTCFQGR-------CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNC--KCKQGWKGKFCNDDVDECLFP----------------VCQQICVNTIGS--YQCSCREGFTLLSN--------------GKCAINCLNNCNKNGDCLNGICYCFSGWH---GEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD---------KCKCPPGYIGHNCEFNDFCHFISPCEHN-------CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNE--------NKCKCPKGFA----GLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIP------------PN-------KKTCLD-----KDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH-----FCMNTEGSYKCS---------CMPGFILSANSHSCQSVCSLCKNGKCD-FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFG------NYECI--CPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVCRDM-SRCYCPIGFHGIDC---------GVD---VDECQRYAPCDKLRGIC 2913
C NGGTC C+C GF G +CQ + N C N CEH CVN + C+C GF+L DG + CS V +G C +C G C+ D L C+ C N Y+C CR GF L N G C +C NN + C C+ G+H +DIDEC N+GCEH C NV G++ C+C G+ L + + C + NGG C D CKC GYI N CH I+ C N C + ++ C C PG+ LM D+KTC+ + G C + C C GF G C +D+NECL N C +C N GS C+C G+ LA D++SC+ PN + +C D K + G SKC C SGY G++C E I + C H C + GS +C C GF S + C+ C NG+CD C C G G+ C + C H N + C C E ++ C + KC+CKPGY G C+ C + GC +C G +C CP GY + C +T C C+NG C + C+C GF+G C G+D + +CQ A CD G C
Sbjct: 123 CHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANEC---MANNGGCEHECVNT-IGTYYCRCWPGFELSGDGNT-----CSDIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGR------AQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDGRTCEEMLGGCQVGNGG-CQHDCYDQPDGGHVCKCRNGYILAN--DQKLCHDINECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSC-HDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADIFSNECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKC-EQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLKCRMD---CPNGRCDPVFGYCTCPDGLYGQSC----------EKPCPHFTFGKNCRFPCKCA-------------RENSEGCDE--------ITGKCRCKPGYYGHHCKR---MCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQPCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCKCQNGAICDTSNGSC 830 HSP 3 Score: 130.568 bits (327), Expect = 2.665e-30 Identity = 142/448 (31.70%), Postives = 199/448 (44.42%), Query Frame = 1
Query: 1804 NMVCSCLPGYDLMPDKKTCKKLECPKCV---RGTC-------NENKCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGY----RGKRCDEDINECKKYSHICEHFCMNTEGS--YKCSCMPGFILSANSHSCQSVCSLCKN-GKCDFN-------NKCKCKTGWT---GELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGG---KCVNSK-----CKCKPGY---NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRG----ICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAV 3006
+ V C PG+ P + C++ C + GTC NE C+CP GF G C+ D NEC+ N C+H C NTIG+++CRC G +L+ D +C ++ + C +C NS +C C S G+ C + + C + CEH C N Y+C C GF LS N SCQ V N G C + +C+C G+ VDIDEC N + C+H C N G+Y C C + L DGR+C E C NGG C + CKC+ GY N DINEC + C C N G+ EC C PG+ ++ D+KTC+ ++ + N C +C + Y G + D C C G +C N GS CQC + Y+L +D SC+ ++
Sbjct: 95 HTVAECCPGWVHRPGEAGCQRANCSADLCHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANECMANNGGCEHECVNTIGTYYCRCWPGFELSGDGNTCSDIDECAVSNGGCSD-RCVNSPGGFRCDCPSDLYLHADGRTCGK-VTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAKN-NGCEHFCENVKGTYRCKCREGYQLGR-DGRTCEEMLGGCQV--GNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECH--ENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQ--ICSNQEGGYMCSCEPGFELSEDGHSCHDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSA 532 HSP 4 Score: 124.405 bits (311), Expect = 2.133e-28 Identity = 226/819 (27.59%), Postives = 310/819 (37.85%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGI----KETQNNCLELRTC---SKGCQNGGTCFQGR--CQCTEGFE---GDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNC--------------KCKQGW----KGKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCL--------NGICYCFSGWH----GEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKS------------------CNI---ECLNGGLCDK------DKCKCPPGYIGHNCEFNDFC---HFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECP--------------KCVRGTCNE--NKCKCPKGFAGLLCENDINECLNQTICQHVC----TNTIG----SFFCRCKNGHKLAEDKRSCIP-------PNKKTC---LDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGFILSANSH---------SCQSVCSLCKNGK-CDFNN-KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGR----------SCLEKNDS----------CSSPCKNGGKC--VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGN----------------YECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVC-RDMSRCYCPIGFHGIDCGVDVDE 2871
C H C D + C C + E + +C + C GCQ+ T GR CQC GF + ++I+ C++ N CEH C N + ++CKC+ G+QL DG++C + G +V +G C KC+ G+ K C+D ++EC C QICVN GS +C C+ GF L+ + K + + NG C +C C G+ G C D++EC N+ GC LC N GS CQC +G+ L ++K C++ S C + +C NGG C KC CP GY G CE C ++ C H C+ +C G D + C CP C G C+ C CP G G CE C+ C N+ G + CRCK G+ KR C P K +C + D V G C C +GY+G CD+ Y C H C G+ C C PGF + S C +C C+NG CD +N C+C GW+G+ CD C + S C C + DG C E DS CS C+NG C V C+C+PG+ G C+ + ++ GC C T N EC CP G+ D Q +C + C C NG C R C CP GF G +C + E
Sbjct: 248 CEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAK----NNGCEHFCENV-KGTYRCKCREGYQLGRDGRTCEE----MLGGCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHD-INECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCH-DMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADIFSNECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCE--QICRNGYWGVDCAHKCSC----KLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKK---CPAGYQGNLCDQPCAP-NTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCK-CQNGAICDTSNGSCECAPGWSGKKCD----------KACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICS--CQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRF---GEGCNAICDCTTTNDTSMYNPFVARCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPE 1029 HSP 5 Score: 96.6709 bits (239), Expect = 6.082e-20 Identity = 166/629 (26.39%), Postives = 233/629 (37.04%), Query Frame = 1
Query: 823 VKSRCYCETGWFGERCVILEP-----ELCKQRKLLFCVHGCSFDKRKLDFSCICGI--KETQNNCLE-------LRTCSKGCQNGGTCFQ--GRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHIC-----VNEGENNFQCKCQSGFQLDNDGKSCIKE----------ECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV-CQQI--CVNTIG----SYQCSCREGFT------LLSNGKCAINCLNNC----NKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD--KCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCK--------KLECPKCVRGTCNEN--KCKCPKGFAGLLCENDIN------------ECLNQTICQHV---CTNTIGSFFCRCK----NGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINE------CKKYSHICEHFCMNTEGSYKC-----------SCMPGFILSANSHSCQSVCSLCKNGKCDF-NNKCKCKTGWTGELCDVDI 2397
V C C GW G C P E C R C +G S D+ C G K ++ C E ++ C C +GG C + G C+C +G+ G C+ C GQ G R C C + +C+C G+ ++ KSC+ EC + +SG+C C+ GW+GK CN + F C Q C N+ S +C C +G+ L +G +C C N D ++G C+C G G DC + ++ C LC C NGG+CD C CPPGYIG CE F C I CE+ T C CLPG+ M + C K +C +C G CN + +CKC GF G CE EC Q C V C G + RC+ NG +SC N C D +C+C +G++G +C++ +E C + + ++ C T+G C C PG SCQ+ C CD +C C GW G C +++
Sbjct: 965 VTGECRCPAGWTGPDCQTSCPLGRHGEGC--RHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCL--CMHGGECNKENGDCECIDGWTGPSCEF---LCPFGQFG-RNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCECENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLC-------------------------------SCENGGVCDSSTGSCVCPPGYIGTKCEIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTCNQVCPEGRFGAGCKEKC-RCANGHCNASSGECKCNLGFTGPSCEQSCPSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGAD--------GRCLCPAGFQGDKCEQKCSEGSFGPACSQQCNCGKYKCDATDGKCICPVGRHGPLCEEECRPGRY----GQSCQNKCQCFNGATCDARTGQCSCSPGWLGPTCQIEM 1541 HSP 6 Score: 87.4261 bits (215), Expect = 3.912e-17 Identity = 187/742 (25.20%), Postives = 292/742 (39.35%), Query Frame = 1
Query: 1024 CQNGGTC--FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHIC-----VNEGENNFQCKCQSGFQLDNDGKSCIKE----------ECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLF-----PVCQQICVNTIGSY------------QCSCREGFT------LLSNGKCAINCLNNCN-KNG---DCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGS------FNCQCHSGFTLQINKKKCI--------SKSCNIECLNGGLCDK--DKCKCPPGYIGHNCEFNDFC-HFISPCEHNCTTINDNMV------CSCLPGYDLMPDKKTCKK----LECPKCVR----GTCNE--NKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSF------FCRCKNGHKLAEDKRSCIPPNKKTCLDKDCV---HGQCFNS--KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEG------SYKCSCMPGFILSANSHSCQSVCS------------LCKNGKCDFNN-KCKCKTGWTGELCDVDIDE------CLLN-----QHKC---QHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC--VNSKCKCKPGYNGDSCEEDINECQW-PISKHGC-IGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVCRDMS-RCYCPIGFHGIDCGVDV 2865
CQNG C G C+C G+ G +C +C+ G G + C C ++ ++ +C C G + ++C C T + V+G+C+C+ GW+GK C+ + F +C N Y +C C G+T G+ C ++C NG D + G C C SG+ G++C + E + C C+ + G +C+C G+T + C ++ CN C NG CD+ +C+C PG+ G +CE + H+ + CE C N + CSC PG+ + C K C + R +C+ +C+CPKG+AG C + C C S C CK GH ++ K C+ ++ C G C +S C+C GY G +C E + ++ CE C G + +C C+PGF +C VC C NG C+ ++ +CKC G+TG C+ C L+ Q +C Q C G Y C S +G + SCS C+NG C + +C C G+ GD CE+ +E + P C G+ + + +CICP G ++ C+ C C NG C + +C C G+ G C +++
Sbjct: 817 CQNGAICDTSNGSCECAPGWSGKKCD---KACAPGTFG-KDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTNDTSMYNPFVARCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCLCMHGGECNKENGDCECIDGWTGPSCEFLCPFGQFGRNCAQRCN--CKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCECENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCSCENGGVCDSSTGSCVCPPGYIGTKC-EIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFT----GMTCNQVCPEGRFGAGCKEKCRCANGHCNASSGECKCNLGFTGPSCEQSCPSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQF----SCPNGFYGWYCSQSCS--CQNGAHCDGADGRCLCPAGFQGDKCEQKCSEGSFGPACSQQCNCGKYKCDATDGKCICPVGRHGPLCEEECRPGRYGQSCQNKCQCFNGATCDARTGQCSCSPGWLGPTCQIEM 1541 HSP 7 Score: 83.1889 bits (204), Expect = 9.328e-16 Identity = 202/816 (24.75%), Postives = 305/816 (37.38%), Query Frame = 1
Query: 802 CGEHGICVKSRCYCETGWFGERCVILEPELCKQRKL-LFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEIN---------------SCSRGQMGNRTCEHIC--VNEGEN-NFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQI---------CVNTIGSYQCSCREGFTL-LSNGKCAINCLN-NCNKNGDCLNGI--------CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSF------NCQCHSGFTLQINKKKC----ISKSCN--IECLNGGLCDKD--KCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCN--------------------ENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSF------FCRCKNGHKLAEDKRSCIPPN------KKTCLDKDCVHG-QC--FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGF---------ILSANSHSCQSVCSLCKNGK-CD-FNNKCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNG--SYSCSCNLPFYLSTVDGRSCLEK------NDSCSSPCKNGGK----CVNSKCKCKPGYNGDSCEEDINECQW-PISKHGCI----GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVC-RDMSRCYCPIGFHGIDC 2853
C G + S+C C +G+ GE+C ++C+ + C H CS +C C + CS G C +GF G QC L+ +C G G ++CE C G+N F CKC + +++G + ++G C+CK G+ G C LF + C G C G+ L + CA N NC C+NG C+C G++G CS ++ C LC G+ +C+C G++ + K C K C+ +C +G CD +C CPPG GH C+ F C I C++ T + C C PG+ + C + C+ +C+CP G+ G C+ + C+H C + G+ FC C +G + ++ S P K CL C+HG +C N C C G+ G C E + ++ C C G+ +C C+PG+ + C+ C C+NG CD + C C+ GW G+ C+ + +H Q C NS S C P + G SC E +SCS C G ++ KC CKPG++G C+ + ++ P C G C ++ G+ C+CPPGY+ + CQ C +C NGG C R +C C GF G+ C
Sbjct: 561 CSMRGSGLLSKCDCPSGYTGEKCE----QICRNGYWGVDCAHKCSCK--------LCDPSTGSCRCEDPEKCSDG------------PCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYG-QSCEKPCPHFTFGKNCRFPCKCA---RENSEG-------------CDEITGKCRCKPGYYGHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQPCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCKCQNGAICDTSNGSCECAPGWSGKKCDKACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTNDTSMYNPFVARCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGF-MGKNCESECPEGLWGSNCMKHCL---CMHGGECNKENGDCECIDGWTGPSC-EFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCE-CENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYA---GHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCSCENGGVCDSSTGS--CVCPPGYIGTKCEIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTC 1324
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Match: Y64G10A.7 (pep chromosome:WBcel235:IV:14291901:14319564:1 gene:WBGene00013416.1 transcript:Y64G10A.7c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y64G10A.7) HSP 1 Score: 153.68 bits (387), Expect = 1.651e-37 Identity = 176/601 (29.28%), Postives = 242/601 (40.27%), Query Frame = 1
Query: 1282 CKCKQGWKGKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKY-NHGCEHLCVNVPGSFNCQCHSGFTLQINKKKC--------ISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPC-------EHNCTTINDNMVCSCLPGYDLMPDKKTCKKL-ECPKC---------VRGTCNENKCKCPKGFA----GLLCENDINEC-LNQTICQHVCTNTI-GSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFN----SKCICKSGYR---GKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-------------------SPCKNGGKC------VNSKCKCKPGYNGDSCEEDINECQWPIS-KHGCIGE-CRNTFGNYEC---------ICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDC 2853
C+C G+ G C D +EC+ C+ CVNTIG+Y C C GF L +G N C+ DIDEC N GC CVN PG F C C S L + + C + C EC N + +C+C G+ E C + PC +H+CT + C C PG+ L D+++C + EC K V+GT +CKC +G+ G CE + C + CQH C + G C+C+NG+ LA D++ C N+ + DC C N +C CK G+R ++ EDI+EC + CE C N EG Y CSC PGF LS + HSC D++ECL+N C C N GS C C Y+ D +SC+ +DS S C+NGGKC + SKC C GY G+ CE+ W + H C + C + G+ C CP G+ C++ + C+P C CP G +G C
Sbjct: 141 CECPVGFTGAKCQYDANECMANNGGCEHECVNTIGTYYCRCWPGFELSGDG-------NTCS-----------------------DIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLS--ENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGT---YRCKCREGYQLGRDGRTCEEMLGGCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECHENNGDCSQ-ICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCH------------------------------DMNECLINNGGCAQLCKNRKGSRRCQC-FAGYILAHDEKSCVAASDSADIFSNECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLKCRMDCPNGRCDPV---------FGYCTCPDGLYGQSC 665 HSP 2 Score: 137.887 bits (346), Expect = 1.296e-32 Identity = 209/751 (27.83%), Postives = 279/751 (37.15%), Query Frame = 1
Query: 1024 CQNGGTCFQGR-------CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNC--KCKQGWKGKFCNDDVDECLFP----------------VCQQICVNTIGS--YQCSCREGFTLLSN--------------GKCAINCLNNCNKNGDCLNGICYCFSGWH---GEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD---------KCKCPPGYIGHNCEFNDFCHFISPCEHN-------CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNE--------NKCKCPKGFA----GLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIP------------PN-------KKTCLD-----KDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH-----FCMNTEGSYKCS---------CMPGFILSANSHSCQSVCSLCKNGKCD-FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGY----LVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCG-----VDVDECQRYAPCDKLRGIC 2913
C NGGTC C+C GF G +CQ + N C N CEH CVN + C+C GF+L DG + CS V +G C +C G C+ D L C+ C N Y+C CR GF L N G C +C NN + C C+ G+H +DIDEC N+GCEH C NV G++ C+C G+ L + + C + NGG C D CKC GYI N CH I+ C N C + ++ C C PG+ LM D+KTC+ + G C + C C GF G C +D+NECL N C +C N GS C+C G+ LA D++SC+ PN + +C D K + G SKC C SGY G++C E I + C H C + GS +C C GF S + C+ C NG+CD C C G G+ C + C H N + C C E ++ C + KC+CKPGY G C+ C + GC +C CP G + D K C + +C+ CP G+ G DC DV + C + G C
Sbjct: 123 CHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANEC---MANNGGCEHECVNT-IGTYYCRCWPGFELSGDGNT-----CSDIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGR------AQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDGRTCEEMLGGCQVGNGG-CQHDCYDQPDGGHVCKCRNGYILAN--DQKLCHDINECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSC-HDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADIFSNECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKC-EQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLKCRMD---CPNGRCDPVFGYCTCPDGLYGQSC----------EKPCPHFTFGKNCRFPCKCA-------------RENSEGCDE--------ITGKCRCKPGYYGHHCKR---MCSPGLFGAGCA---------MKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQP--------------CPAGYFGYDCEQKCSCADVASPHKSKVCHHVTGTC 793 HSP 3 Score: 130.568 bits (327), Expect = 2.829e-30 Identity = 146/451 (32.37%), Postives = 205/451 (45.45%), Query Frame = 1
Query: 1804 NMVCSCLPGYDLMPDKKTCKKLECPKCV---RGTC-------NENKCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGY----RGKRCDEDINECKKYSHICEHFCMNTEGS--YKCSCMPGFILSANSHSCQSVCSLCKN-GKCDFN-------NKCKCKTGWT---GELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGG---KCVNSK-----CKCKPGY---NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGV---DVDECQ-RYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAV 3006
+ V C PG+ P + C++ C + GTC NE C+CP GF G C+ D NEC+ N C+H C NTIG+++CRC G +L+ D +C ++ + C +C NS +C C S G+ C + + C + CEH C N Y+C C GF LS N SCQ V N G C + +C+C G+ VDIDEC N + C+H C N G+Y C C + L DGR+C E C NGG C + CKC+ GY N DINEC + C C N G+ EC C PG+ ++ D+KTC+ ++ + N C +C + C C GF + G D++EC C +L C N GS CQC + Y+L +D SC+ ++
Sbjct: 95 HTVAECCPGWVHRPGEAGCQRANCSADLCHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANECMANNGGCEHECVNTIGTYYCRCWPGFELSGDGNTCSDIDECAVSNGGCSD-RCVNSPGGFRCDCPSDLYLHADGRTCGK-VTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAKN-NGCEHFCENVKGTYRCKCREGYQLGR-DGRTCEEMLGGCQV--GNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECH--ENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQ--ICSNQEGGYMCSCEPGFELSEDGHSCHDMNECLINNGGCAQL---CKNRKGSRRCQCFAGYILAHDEKSCVAASDSA 532 HSP 4 Score: 117.857 bits (294), Expect = 2.227e-26 Identity = 216/776 (27.84%), Postives = 296/776 (38.14%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGI----KETQNNCLELRTC---SKGCQNGGTCFQGR--CQCTEGFE---GDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNC--------------KCKQGW----KGKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCL--------NGICYCFSGWH----GEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKS------------------CNI---ECLNGGLCDK------DKCKCPPGYIGHNCEFNDFC---HFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECP--------------KCVRGTCNE--NKCKCPKGFAGLLCENDINECLNQTICQHVCT----NTIG----SFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKK------YSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKC-DFNNKCKCKTGWTGELCDVDIDECLLNQH--KCQHNCVNSNGSY------SCSCNLPFYLSTVD-----GRSCLEKNDSCSSPCKNGGKC--VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNY------ECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVCRDMS-RCYCPIGFHGIDC 2853
C H C D + C C + E + +C + C GCQ+ T GR CQC GF + ++I+ C++ N CEH C N + ++CKC+ G+QL DG++C + G +V +G C KC+ G+ K C+D ++EC C QICVN GS +C C+ GF L+ + K + + NG C +C C G+ G C D++EC N+ GC LC N GS CQC +G+ L ++K C++ S C + +C NGG C KC CP GY G CE C ++ C H C+ +C G D + C CP C G C+ C CP G G CE C+ C N+ G + CRCK G+ KR C P + G KC C +G RCD +C K ++C+ C Y C SC V S K+ C C C G TG LCD C N + C H C NG+ SC C FY +T GR ++ C C+NG C N C+C PG++G C++ C C +C G + ECICPPG +TC C C NG C ++ C C G+ G C
Sbjct: 248 CEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAK----NNGCEHFCENV-KGTYRCKCREGYQLGRDGRTCEE----MLGGCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHD-INECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCH-DMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADIFSNECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCE--QICRNGYWGVDCAHKCSC----KLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKRMCSPG----------LFGAGCAMKCSCPAGI---RCDPVTGDCTKKCPAGYQGNLCDQPCPAGYFGYDCE---------QKCSCADVASPHKSKVCHHVTGTCTCLPGKTGPLCD---QSCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCK--CQNGAICDTSNGSCECAPGWSGKKCDK---ACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKC 976 HSP 5 Score: 97.0561 bits (240), Expect = 5.015e-20 Identity = 166/629 (26.39%), Postives = 233/629 (37.04%), Query Frame = 1
Query: 823 VKSRCYCETGWFGERCVILEP-----ELCKQRKLLFCVHGCSFDKRKLDFSCICGI--KETQNNCLE-------LRTCSKGCQNGGTCFQ--GRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHIC-----VNEGENNFQCKCQSGFQLDNDGKSCIKE----------ECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV-CQQI--CVNTIG----SYQCSCREGFT------LLSNGKCAINCLNNC----NKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD--KCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCK--------KLECPKCVRGTCNEN--KCKCPKGFAGLLCENDIN------------ECLNQTICQHV---CTNTIGSFFCRCK----NGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINE------CKKYSHICEHFCMNTEGSYKC-----------SCMPGFILSANSHSCQSVCSLCKNGKCDF-NNKCKCKTGWTGELCDVDI 2397
V C C GW G C P E C R C +G S D+ C G K ++ C E ++ C C +GG C + G C+C +G+ G C+ C GQ G R C C + +C+C G+ ++ KSC+ EC + +SG+C C+ GW+GK CN + F C Q C N+ S +C C +G+ L +G +C C N D ++G C+C G G DC + ++ C LC C NGG+CD C CPPGYIG CE F C I CE+ T C CLPG+ M + C K +C +C G CN + +CKC GF G CE EC Q C V C G + RC+ NG +SC N C D +C+C +G++G +C++ +E C + + ++ C T+G C C PG SCQ+ C CD +C C GW G C +++
Sbjct: 1014 VTGECRCPAGWTGPDCQTSCPLGRHGEGC--RHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCL--CMHGGECNKENGDCECIDGWTGPSCEF---LCPFGQFG-RNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCECENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLC-------------------------------SCENGGVCDSSTGSCVCPPGYIGTKCEIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTCNQVCPEGRFGAGCKEKC-RCANGHCNASSGECKCNLGFTGPSCEQSCPSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGAD--------GRCLCPAGFQGDKCEQKCSEGSFGPACSQQCNCGKYKCDATDGKCICPVGRHGPLCEEECRPGRY----GQSCQNKCQCFNGATCDARTGQCSCSPGWLGPTCQIEM 1590 HSP 6 Score: 82.0333 bits (201), Expect = 1.689e-15 Identity = 206/850 (24.24%), Postives = 314/850 (36.94%), Query Frame = 1
Query: 802 CGEHGICVKSRCYCETGWFGERCVILEPELCKQRKL-LFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEIN---------------SCSRGQMGN---RTCEHI-----------CVNEG-----ENNFQCKCQSGFQLDNDGKSC----------IKEECSKFGTTEVVSGNC--KCKQGWKGKFCNDDVDECLF---------------PVCQQICVNTIGSYQCSCREGFT-LLSNGKCAINCLN-NCNKNGDCLNGI--------CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSF------NCQCHSGFTLQINKKKC----ISKSCN--IECLNGGLCDKD--KCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCN--------------------ENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSF------FCRCKNGHKLAEDKRSCIPPN------KKTCLDKDCVH-GQC--FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGF---------ILSANSHSCQSVCSLCKNGK-CD-FNNKCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNG--SYSCSCNLPFYLSTVDGRSCLEK------NDSCSSPCKNGG----KCVNSKCKCKPGYNGDSCEEDINECQW-PISKHGCI----GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVC-RDMSRCYCPIGFHGIDC 2853
C G + S+C C +G+ GE+C ++C+ + C H CS +C C + CS G C +GF G QC L+ +C G G + C H C E E +C+C+ G+ + + C +K C + V+G+C KC G++G C+ F P ++C + G+ C+C G T L + CA N NC C+NG C+C G++G CS ++ C LC G+ +C+C G++ + K C K C+ +C +G CD +C CPPG GH C+ F C I C++ T + C C PG+ + C + C+ +C+CP G+ G C+ + C+H C + G+ FC C +G + ++ S P K CL C+H G+C N C C G+ G C E + ++ C C G+ +C C+PG+ + C+ C C+NG CD + C C+ GW G+ C+ + +H Q C NS S C P + G SC E +SCS C G ++ KC CKPG++G C+ + ++ P C G C ++ G+ C+CPPGY+ + CQ C +C NGG C R +C C GF G+ C
Sbjct: 561 CSMRGSGLLSKCDCPSGYTGEKCE----QICRNGYWGVDCAHKCSCK--------LCDPSTGSCRCEDPEKCSDG------------PCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQPCPAGYFGYDCEQKCSCADVASPHKSKVCHHVTGT--CTCLPGKTGPLCDQSCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCKCQNGAICDTSNGSCECAPGWSGKKCDKACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTNDTSMYNPFVARCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGF-MGKNCESECPEGLWGSNCMKHCL---CMHGGECNKENGDCECIDGWTGPSC-EFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCE-CENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYA---GHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCSCENGGVCDSSTGS--CVCPPGYIGTKCEIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTC 1373 HSP 7 Score: 79.7221 bits (195), Expect = 1.062e-14 Identity = 180/698 (25.79%), Postives = 252/698 (36.10%), Query Frame = 1
Query: 1024 CQNGGTC--FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHIC-----VNEGENNFQCKCQSGFQLDNDGKSCIKE----------ECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLF-PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSF------NCQCHSGFTLQINKKKC----ISKSCNIECL--NGGLCDKD--KCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIND------NMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHG-QCFNSK--------CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGF---------ILSANSHSCQSVCSLCKNGKCDFN-NKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNG------SYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVN-------SKCKCKPGYNGDSCEEDINECQWPISKHG--------CIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVCRDM-SRCYCPIGFHGIDC 2853
CQNG C G C+C G+ G +C +C+ G G + C C ++ ++ +C C G + ++C C T + V+G+C+C+ GW+GK C+ + F C IC T + T + N A D + G C C +GW G DC ++ GC H C G+ C C SGF + + +C +C CL +GG C+K+ C+C G+ G +CEF F F C C N C CLPG+ +K+C G G CE + EC N +C + S C C+ G + + R C+ K + C +C NSK C C GY G C E + + C C E S KC C PG + C +CS G CD + C C G+ G C++ C+ C NG + C C LP + + C E + CK +C N +CKC G+ G SCE+ P K+G C G+ R C CPPG Q +C C+ C NG C RC CP GF G C
Sbjct: 866 CQNGAICDTSNGSCECAPGWSGKKCD---KACAPGTFG-KDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTND--------TSMYNPFVA---------RCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCLCMHGGECNKENGDCECIDGWTGPSCEFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCEKSCV--------------------SGHYGAKCE-ETCECENGALCDPI------SGHCSCQPGWRGKKCNRPCL----KGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPD-GTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCSCENGGVCDSSTGSCVCPPGYIGTKCEIACQSDRFGP-TCEKICNCENGGTCDRLTGQCRC-LPGFTGMTCNQVCPEGRF--GAGCKEKCRCANGHCNASSGECKCNLGFTGPSCEQSC-----PSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGADGRCLCPAGFQGDKC 1501
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Match: Y64G10A.7 (pep chromosome:WBcel235:IV:14291901:14319564:1 gene:WBGene00013416.1 transcript:Y64G10A.7b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y64G10A.7) HSP 1 Score: 141.739 bits (356), Expect = 1.026e-33 Identity = 163/563 (28.95%), Postives = 214/563 (38.01%), Query Frame = 1
Query: 1024 CQNGGTCFQGR-------CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNC--KCKQGWKGKFCNDDVDECLFP----------------VCQQICVNTIGS--YQCSCREGFTLLSN--------------GKCAINCLNNCNKNGDCLNGICYCFSGWH---GEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD---------KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYD----LMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCE--NDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDS 2532
C NGGTC C+C GF G +CQ + N C N CEH CVN + C+C GF+L DG + CS V +G C +C G C+ D L C+ C N Y+C CR GF L N G C +C NN + C C+ G+H +DIDEC N+GCEH C NV G++ C+C G+ L + + C + NGG C D CKC GYI N CH N +T+ Y+ + P TC KL C+ +C C G+ + + DINEC N C +C N GS C+CK G +L +D+++C EDI+EC + CE C N EG Y CSC PGF LS + HSC D++ECL+N C C N GS C C Y+ D +SC+ +DS
Sbjct: 123 CHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANEC---MANNGGCEHECVNT-IGTYYCRCWPGFELSGDGNT-----CSDIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGR------AQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDGRTCEEMLGGCQVGNGG-CQHDCYDQPDGGHVCKCRNGYILAN--DQKLCH------DNISTVIHARAPRLWDSYETVTCVTPTDLTCHKL----CMHLDSGHVQCFCDDGYELIDSKFCQDINECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTC-----------------------------------EDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCH------------------------------DMNECLINNGGCAQLCKNRKGSRRCQC-FAGYILAHDEKSCVAASDS 591 HSP 2 Score: 130.568 bits (327), Expect = 2.420e-30 Identity = 135/455 (29.67%), Postives = 196/455 (43.08%), Query Frame = 1
Query: 1804 NMVCSCLPGYDLMPDKKTCKKLECPKCV---RGTC-------NENKCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGY----RGKRCDEDINECKKYSHICEHFCMNTEGS--YKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLE-----KNDSCSSPCKNGGKCVNSKCKCKPGY----NGDSCEEDINECQWPISKHGCIGECRNTF-GNYECICPPGYLVLDDQKTCQ-----------------------ISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGV--DVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
+ V C PG+ P + C++ C + GTC NE C+CP GF G C+ D NEC+ N C+H C NTIG+++CRC G +L+ D +C ++ + C +C NS +C C S G+ C + + C + CEH C N Y+C C GF LS N SCQ V D C N+ CQH+C N++G C C F+LS D RSC++ KN+ C C+N +CKC+ GY +G +CEE + CQ + GC +C + G + C C GY++ +DQK C ++ D C+ C++ + +C+C G+ ID D++EC IC N GS CQC + LM D +C + E
Sbjct: 95 HTVAECCPGWVHRPGEAGCQRANCSADLCHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANECMANNGGCEHECVNTIGTYYCRCWPGFELSGDGNTCSDIDECAVSNGGCSD-RCVNSPGGFRCDCPSDLYLHADGRTCGK-VTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPV------------------------------DPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLS-YDRRSCVDIDECAKNNGCEHFCENVKG--TYRCKCREGYQLGRDGRTCEEMLGGCQ--VGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDNISTVIHARAPRLWDSYETVTCVTPTDLTCHKLCMH--LDSGHVQCFCDDGYELIDSKFCQDINECHENN--GDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISE 508 HSP 3 Score: 120.939 bits (302), Expect = 2.094e-27 Identity = 146/518 (28.19%), Postives = 224/518 (43.24%), Query Frame = 1
Query: 1603 QCHSGFTLQINKKKCISKSCNIE-CLNGGLC-------DKDKCKCPPGYIGHNCEF--NDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGF-----AGLLCENDINECLNQTIC-------QHVCTN-TIGSFF-CRCKNGHKLAEDKRSCIPPNKKTCLDKD--CVHGQCFN----SKCICKSGYR---GKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCK--NGKC--------DFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKND-SCSSPCKNGGKCVNSKCKCKPGYNGDSCE--EDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRG----ICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAV 3006
+C G+ + + C +C+ + C NGG C ++ C+CP G+ G C++ N+ CEH C C C PG++L D TC ++ G C++ P GF + L D C T C +H C N + G F+ CRC+ G KL+E+KRSC P + C D C H C N ++C C G+ +R DI+EC K ++ CEHFC N +G+Y+C C G+ L + +C+ + C+ NG C D + CKC+ G+ L N K H+ N S P + + +C+ D +C C + + +C C GY + +DINEC + C C N G+ EC C PG+ ++ D+KTC+ ++ + N C +C + Y G + D C C G +C N GS CQC + Y+L +D SC+ ++
Sbjct: 99 ECCPGWVHRPGEAGCQRANCSADLCHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANECMANNGGCEHECVNTIGTYYCRCWPGFELSGDGNTCSDIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDP--CFDNKGGCQH-HCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAK-NNGCEHFCENVKGTYRCKCREGYQLGRDGRTCEEMLGGCQVGNGGCQHDCYDQPDGGHVCKCRNGYI-----------LANDQKLCHD----NISTVIHARAPRLWDSYETVTCVTPTDLTCHKLCMHLDS-GHVQCFCDDGYELIDSKFCQDINECH--ENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQ--ICSNQEGGYMCSCEPGFELSEDGHSCHDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSA 592 HSP 4 Score: 96.6709 bits (239), Expect = 5.862e-20 Identity = 162/612 (26.47%), Postives = 226/612 (36.93%), Query Frame = 1
Query: 823 VKSRCYCETGWFGERCVILEPELCKQR---KLLFCVHGCSFDKRKLDFSCICGIKETQNNCLEL-------RTCSK--GCQNGGTCFQ--GRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV-CQQI--CVNTIG----SYQCSCREGFT------LLSNGKCAINCLNNC----NKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD--KCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCK--------KLECPKCVRGTCNEN--KCKCPKGFAGLLCENDIN------------ECLNQTICQHV---CTNTIGSFFCRCK----NGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINE------CKKYSHICEHFCMNTEGSYKC-----------SCMPGFILSANSHSCQSVCSLCKNGKCDF-NNKCKCKTGWTGELCDVDI 2397
V C C +G+ G+ C PE K C+HG +K D CI G T +C L R C++ C+NG +C + GRC+C G+ G+ C+ SC G G + CE C EC + +SG+C C+ GW+GK CN + F C Q C N+ S +C C +G+ L +G +C C N D ++G C+C G G DC + ++ C LC C NGG+CD C CPPGYIG CE F C I CE+ T C CLPG+ M + C K +C +C G CN + +CKC GF G CE EC Q C V C G + RC+ NG +SC N C D +C+C +G++G +C++ +E C + + ++ C T+G C C PG SCQ+ C CD +C C GW G C +++
Sbjct: 1159 VTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCLCMHGGECNKENGDCECIDGW--TGPSCEFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCE---KSCVSGHYGAK-CEETC----------------------------ECENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLC-------------------------------SCENGGVCDSSTGSCVCPPGYIGTKCEIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTCNQVCPEGRFGAGCKEKC-RCANGHCNASSGECKCNLGFTGPSCEQSCPSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGAD--------GRCLCPAGFQGDKCEQKCSEGSFGPACSQQCNCGKYKCDATDGKCICPVGRHGPLCEEECRPGRY----GQSCQNKCQCFNGATCDARTGQCSCSPGWLGPTCQIEM 1692 HSP 5 Score: 87.4261 bits (215), Expect = 4.157e-17 Identity = 210/804 (26.12%), Postives = 317/804 (39.43%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICG--IKETQNNCLELRTCSK--GCQNGGTCFQG--RCQCTEGFE----GDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSC-------IKEECSK-FGTTEVV------------------SGN--CKCKQGWK---GKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCL--------NGICYCFSGWH----GEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTI---NDNMVCSCLPGYDLMPDKKTCKKLECPKC-------VRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTI---GSFFCRCKNGHKLAE----DKRSCIPPNKKTCLDKDCVHGQC--FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCM----NTEG----SYKCSCMPGFILSANSHSCQSVCS------------LCKNG-KCD-FNNKC--KCKTGWTGELCDVDIDECLLNQHKCQHNC------------VNSNGSYSCSCNLPFYLSTVDGRSCLE----KNDSCSSPCKNGGKCVNS--KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFG------NYECICPPGYLVLDDQKTCQISTKDTMCNPH--CLNGGVCRDM-SRCYCPIGFHGIDCGVDVD------------ECQRYAPCDKLRGIC 2913
C H C+ + + C G + + +C+++ C+K GC++ +G RC+C EG++ G C+ + C Q+GN C+H C ++ + CKC++G+ L ND K C I + + + E V SG+ C C G++ KFC D++EC C QICVN GS +C C+ GF L+ + K + + NG C +C C G+ G C D++EC N+ GC LC N GS CQC +G+ L ++K C++ S + + + + D K PG + + + P + + + V C G+ TC +L C C +RG+ +KC CP G+ G CE C H C+ + + CRC++ K ++ D N K DC +G+C C C G G+ C++ + C C N+EG + KC C PG+ H C+ +CS C G +CD C KC G+ G LCD + C+ C V + + +C+C LP + +SC N + + C NG KC S C C PG+ G +C E ++ I C+ C+ G N C C PG+ K C T C+ C +G C C CP G G C D CQ A CD + G C
Sbjct: 291 CQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDGRTCEEMLGGC---QVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDNISTVIHARAPRLWDSYETVTCVTPTDLTCHKLCMHLDSGHVQCFCDDGYELIDSKFCQ-DINECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCH-DMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADIFSNDIEDYSK---VPGLDSIDEVISSIESY--PADESPRPLVFGRRRHVKECPNGF----FGSTC-QLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLK--CRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPH-FTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYY----GHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQPCPAGYFG-YDCEQKCSCADVASPHKSKVCHHVTGTCTC-LPGKTGPLCDQSCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGID---CMQLCKCQNGAICDTSNGSCECAPGWSGKKCDKACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSC 1067 HSP 6 Score: 82.4185 bits (202), Expect = 1.473e-15 Identity = 207/850 (24.35%), Postives = 314/850 (36.94%), Query Frame = 1
Query: 802 CGEHGICVKSRCYCETGWFGERCVILEPELCKQRKL-LFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEIN---------------SCSRGQMGN---RTCEHI-----------CVNEG-----ENNFQCKCQSGFQLDNDGKSC----------IKEECSKFGTTEVVSGNC--KCKQGWKGKFCNDDVDECLF---------------PVCQQICVNTIGSYQCSCREGFT-LLSNGKCAINCLN-NCNKNGDCLNGI--------CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSF------NCQCHSGFTLQINKKKC----ISKSCN--IECLNGGLCDKD--KCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTC--------------------KKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSF------FCRCKNGHKLAEDKRSCIPPN------KKTCLDKDCVH-GQC--FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGF---------ILSANSHSCQSVCSLCKNGK-CD-FNNKCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNG--SYSCSCNLPFYLSTVDGRSCLEK------NDSCSSPCKNGG----KCVNSKCKCKPGYNGDSCEEDINECQW-PISKHGCI----GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVC-RDMSRCYCPIGFHGIDC 2853
C G + S+C C +G+ GE+C ++C+ + C H CS +C C + CS G C +GF G QC L+ +C G G + C H C E E +C+C+ G+ + + C +K C + V+G+C KC G++G C+ F P ++C + G+ C+C G T L + CA N NC C+NG C+C G++G CS ++ C LC G+ +C+C G++ + K C K C+ +C +G CD +C CPPG GH C+ F C I C++ T + C C PG+ + C + P R +C+CP G+ G C+ + C+H C + G+ FC C +G + ++ S P K CL C+H G+C N C C G+ G C E + ++ C C G+ +C C+PG+ + C+ C C+NG CD + C C+ GW G+ C+ + +H Q C NS S C P + G SC E +SCS C G ++ KC CKPG++G C+ + ++ P C G C ++ G+ C+CPPGY+ + CQ C +C NGG C R +C C GF G+ C
Sbjct: 663 CSMRGSGLLSKCDCPSGYTGEKCE----QICRNGYWGVDCAHKCSCK--------LCDPSTGSCRCEDPEKCSDG------------PCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQPCPAGYFGYDCEQKCSCADVASPHKSKVCHHVTGT--CTCLPGKTGPLCDQSCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCKCQNGAICDTSNGSCECAPGWSGKKCDKACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTNDTSMYNPFVARCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGF-MGKNCESECPEGLWGSNCMKHCL---CMHGGECNKENGDCECIDGWTGPSC-EFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCE-CENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYA---GHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCSCENGGVCDSSTGS--CVCPPGYIGTKCEIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTC 1475 HSP 7 Score: 82.0333 bits (201), Expect = 2.033e-15 Identity = 183/739 (24.76%), Postives = 266/739 (35.99%), Query Frame = 1
Query: 1054 RCQCTEGF---EGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIK-EECSKFGTTEVVSGN------CKCKQGWK----GKFCNDDVDECLF--PVCQQICVNTI-GSYQCSCREGFTLLSNGKC---------------------AINCLN----NCNK---NGDCLNGICYCFSGWHGEDCSL--DIDECKYNHG-CEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECL--NGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRG-KRCDEDINECKKY-SHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKN-GKCDFN-----NKCKCKTGWTGE----------------------LCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGR--------SCLEK--NDSCSSPCKN---GGKC----------------VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGY----LVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCG-----VDVDECQRYAPCDKLRGIC 2913
RC+C GF E + ++ C + G C+H C N QC+C GF L D +SC+ +EC+K E N CKC++G++ G+ C + + C CQ C + G + C CR G+ L ++ K + C+ C+K + D + C+C G+ D DI+EC N+G C +CVN+ GS CQC GF L ++K C S EC NGG CE C+ +CSC PG++L D +C +D+NECL N C +C N GS C+C G+ LA D++SC+ + + F++ S G DE I+ + Y + + + C GF S +CQ CS C+N GKC +KC C +G+TGE LCD C + + +G Y CNL + +GR +C + SC PC + G C + KC+CKPGY G C+ C + GC +C CP G + D K C + +C+ CP G+ G DC DV + C + G C
Sbjct: 262 RCRCRVGFKLSENKRSCQPVDPCFDNKGG---CQHHCTNN-HGRAQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDGRTCEEMLGGCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDNISTVIHARAPRLWDSYETVTCVTPTDLTCHKLCMHLDSGHVQCFCDDGYELIDSKFCQDINECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDIS---ECSSNNGG-----------------------------CEQICSNQEGGYMCSCEPGFELSEDGHSC------------------------------HDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADI---------FSNDIEDYSKVPGLDSIDEVISSIESYPADESPRPLVFGRRRHVKECPNGFFGS----TCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKR---MCSPGLFGAGCA---------MKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQP--------------CPAGYFGYDCEQKCSCADVASPHKSKVCHHVTGTC 895 HSP 8 Score: 79.337 bits (194), Expect = 1.204e-14 Identity = 179/698 (25.64%), Postives = 251/698 (35.96%), Query Frame = 1
Query: 1024 CQNGGTC--FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHIC-----VNEGENNFQCKCQSGFQLDNDGKSCIKE----------ECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLF-PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSF------NCQCHSGFTLQINKKKC----ISKSCNIECL--NGGLCDKD--KCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN------DNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHG-QCFNSK--------CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGF---------ILSANSHSCQSVCSLCKNGKCDFNN-KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNG------SYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVN-------SKCKCKPGYNGDSCEEDINECQWPISKHG--------CIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVCRDM-SRCYCPIGFHGIDC 2853
CQNG C G C+C G+ G +C +C+ G G + C C ++ ++ +C C G + ++C C T + V+G+C+C+ GW+GK C+ + F C IC T + + N D + G C C +GW G DC ++ GC H C G+ C C SGF + + +C +C CL +GG C+K+ C+C G+ G +CEF F F C C N C CLPG+ + C+K C G G CE + EC N +C + S C C+ G + + R C+ K + C +C NSK C C GY G C E + + C C E S KC C PG + C +CS G CD + C C G+ G C++ C+ C NG + C C LP + + C E + CK +C N +CKC G+ G SCE+ P K+G C G+ R C CPPG Q +C C+ C NG C RC CP GF G C
Sbjct: 968 CQNGAICDTSNGSCECAPGWSGKKCD---KACAPGTFG-KDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTN-----------------DTSMYNPFVARCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCLCMHGGECNKENGDCECIDGWTGPSCEFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGW----SGEHCEK----------------SCVSGHYGAKCE-ETCECENGALCDPI------SGHCSCQPGWRGKKCNRPCL----KGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPD-GTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCSCENGGVCDSSTGSCVCPPGYIGTKCEIACQSDRFGP-TCEKICNCENGGTCDRLTGQCRC-LPGFTGMTCNQVCPEGRF--GAGCKEKCRCANGHCNASSGECKCNLGFTGPSCEQSC-----PSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGADGRCLCPAGFQGDKC 1603 HSP 9 Score: 69.707 bits (169), Expect = 1.090e-11 Identity = 194/763 (25.43%), Postives = 256/763 (33.55%), Query Frame = 1
Query: 1054 RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEE--------CSKFGTTEVVSGNCKCKQGW---------------KGKFCNDDVDECLFPVCQQI--CVNTIGSYQC----------------SCREGFTLLSNGKCAINCLNN--CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH-----LCVNVPGSFNCQ---------CHSGF-TLQINKKKCISKSCNIECLNGGLCDK--DKCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMV--CSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQ-------TICQHVCTNTIGSFFCRCKNGHKLAEDKRSCI---PPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGFILSANSH---------SCQSVCSLCKNGK-CDFNN-KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGR----------SCLEKNDS----------CSSPCKNGGKC--VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCM 2988
CQC GF + + S N CE IC N+ E + C C+ GF+L DG SC C++ S C+C G+ F ND D P I +++I SY C GF + +C N C+ G L C C SG+ GE C + C H LC GS C+ C GF Q N K C ++C NG CD C CP G G +CE F C F C + D + C C PGY CK++ P C KC CP AG+ C+ +C + +C C + C E K SC P+K K C H C C G G CD+ Y C H C G+ C C PGF + S C +C C+NG CD +N C+C GW+G+ CD C + S C C + DG C E DS CS C+NG C V C+C+PG+ G C+ + ++ GC C T N + P ++ D T + P C CP+G HG C +C A CD++ G C G C S G++CM
Sbjct: 487 ECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQ-EGGYMCSCEPGFELSEDGHSCHDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADIFSNDIEDYSKVPGLDSIDEVISSIESYPADESPRPLVFGRRRHVKECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLK------CRMDCPNG-RCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYY----GHHCKRMCSPGLFGAGC-AMKCSCP---AGIRCDPVTGDCTKKCPAGYQGNLCDQPCPAGYFGYDC---------EQKCSCADVASPHKS----KVCHH---VTGTCTCLPGKTGPLCDQSCAP-NTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCK-CQNGAICDTSNGSCECAPGWSGKKCD----------KACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICS--CQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRF---GEGCNAICDCTTTNDTSMYNP-FVARCDHVTGECRCPAGWTGPDCQT----------SCPLGRHGEGCRHSC-QCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCM 1188
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Match: Y64G10A.7 (pep chromosome:WBcel235:IV:14291901:14319564:1 gene:WBGene00013416.1 transcript:Y64G10A.7d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y64G10A.7) HSP 1 Score: 140.198 bits (352), Expect = 2.999e-33 Identity = 142/458 (31.00%), Postives = 194/458 (42.36%), Query Frame = 1
Query: 1282 CKCKQGWKGKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKY-NHGCEHLCVNVPGSFNCQCHSGFTLQINKKKC--------ISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPC-------EHNCTTINDNMVCSCLPGYDLMPDKKTCKKL-ECPKC---------VRGTCNENKCKCPKGFA----GLLCENDINEC-LNQTICQHVCTNTI-GSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFN----SKCICKSGYR---GKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDS 2532
C+C G+ G C D +EC+ C+ CVNTIG+Y C C GF L +G N C+ DIDEC N GC CVN PG F C C S L + + C + C EC N + +C+C G+ E C + PC +H+CT + C C PG+ L D+++C + EC K V+GT +CKC +G+ G CE + C + CQH C + G C+C+NG+ LA D++ C N+ + DC C N +C CK G+R ++ EDI+EC + CE C N EG Y CSC PGF LS + HSC D++ECL+N C C N GS C C Y+ D +SC+ +DS
Sbjct: 141 CECPVGFTGAKCQYDANECMANNGGCEHECVNTIGTYYCRCWPGFELSGDG-------NTCS-----------------------DIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLS--ENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGT---YRCKCREGYQLGRDGRTCEEMLGGCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECHENNGDCSQ-ICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCH------------------------------DMNECLINNGGCAQLCKNRKGSRRCQC-FAGYILAHDEKSCVAASDS 531 HSP 2 Score: 134.035 bits (336), Expect = 2.164e-31 Identity = 219/785 (27.90%), Postives = 298/785 (37.96%), Query Frame = 1
Query: 1024 CQNGGTCFQGR-------CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNC--KCKQGWKGKFCNDDVDECLFP----------------VCQQICVNTIGS--YQCSCREGFTLLSN--------------GKCAINCLNNCNKNGDCLNGICYCFSGWH---GEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD---------KCKCPPGYIGHNCEFNDFCHFISPCEHN-------CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNE--------NKCKCPKGFA----GLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRG-KRCDEDINECKKY-SHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKN-GKCDFN-----NKCKCKTGWTGE----------------------LCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGR--------SCLEK--NDSCSSPCKN---GGKC----------------VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFG------NYECI--CPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVCRDM-SRCYCPIGFHGIDC---------GVD---VDECQRYAPCDKLRGIC 2913
C NGGTC C+C GF G +CQ + N C N CEH CVN + C+C GF+L DG + CS V +G C +C G C+ D L C+ C N Y+C CR GF L N G C +C NN + C C+ G+H +DIDEC N+GCEH C NV G++ C+C G+ L + + C + NGG C D CKC GYI N CH I+ C N C + ++ C C PG+ LM D+KTC+ + G C + C C GF G C +D+NECL N C +C N GS C+C G+ LA D++SC+ + + F++ S G DE I+ + Y + + + C GF S +CQ CS C+N GKC +KC C +G+TGE LCD C + + +G Y CNL + +GR +C + SC PC + G C + KC+CKPGY G C+ C + GC +C G +C CP GY + C +T C C+NG C + C+C GF+G C G+D + +CQ A CD G C
Sbjct: 123 CHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANEC---MANNGGCEHECVNT-IGTYYCRCWPGFELSGDGNT-----CSDIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGR------AQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDGRTCEEMLGGCQVGNGG-CQHDCYDQPDGGHVCKCRNGYILAN--DQKLCHDINECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSC-HDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADI---------FSNDIEDYSKVPGLDSIDEVISSIESYPADESPRPLVFGRRRHVKECPNGFFGS----TCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKR---MCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQPCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCKCQNGAICDTSNGSC 872 HSP 3 Score: 130.954 bits (328), Expect = 2.023e-30 Identity = 146/451 (32.37%), Postives = 205/451 (45.45%), Query Frame = 1
Query: 1804 NMVCSCLPGYDLMPDKKTCKKLECPKCV---RGTC-------NENKCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGY----RGKRCDEDINECKKYSHICEHFCMNTEGS--YKCSCMPGFILSANSHSCQSVCSLCKN-GKCDFN-------NKCKCKTGWT---GELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGG---KCVNSK-----CKCKPGY---NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGV---DVDECQ-RYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAV 3006
+ V C PG+ P + C++ C + GTC NE C+CP GF G C+ D NEC+ N C+H C NTIG+++CRC G +L+ D +C ++ + C +C NS +C C S G+ C + + C + CEH C N Y+C C GF LS N SCQ V N G C + +C+C G+ VDIDEC N + C+H C N G+Y C C + L DGR+C E C NGG C + CKC+ GY N DINEC + C C N G+ EC C PG+ ++ D+KTC+ ++ + N C +C + C C GF + G D++EC C +L C N GS CQC + Y+L +D SC+ ++
Sbjct: 95 HTVAECCPGWVHRPGEAGCQRANCSADLCHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANECMANNGGCEHECVNTIGTYYCRCWPGFELSGDGNTCSDIDECAVSNGGCSD-RCVNSPGGFRCDCPSDLYLHADGRTCGK-VTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAKN-NGCEHFCENVKGTYRCKCREGYQLGR-DGRTCEEMLGGCQV--GNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECH--ENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQ--ICSNQEGGYMCSCEPGFELSEDGHSCHDMNECLINNGGCAQL---CKNRKGSRRCQCFAGYILAHDEKSCVAASDSA 532 HSP 4 Score: 104.76 bits (260), Expect = 2.110e-22 Identity = 208/758 (27.44%), Postives = 305/758 (40.24%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGI----KETQNNCLELRTC---SKGCQNGGTCFQGR--CQCTEGFE---GDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNC--------------KCKQGW----KGKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCL--------NGICYCFSGWH----GEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTI---NDNMVCSCLPGYDLMPDKKTCKKLECPKC-------VRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTI---GSFFCRCKNGHKLAE----DKRSCIPPNKKTCLDKDCVHGQC--FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCM----NTEG----SYKCSCMPGFILSANSHSCQSVCS------------LCKNG-KCD-FNNKC--KCKTGWTGELCDVDIDECLLNQH--KCQHNCVNSNGSY------SCSCNLPFYLSTVD-----GRSCLEKNDSCSSPCKNGGKC--VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNY------ECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVCRDMS-RCYCPIGFHGIDC 2853
C H C D + C C + E + +C + C GCQ+ T GR CQC GF + ++I+ C++ N CEH C N + ++CKC+ G+QL DG++C + G +V +G C KC+ G+ K C+D ++EC C QICVN GS +C C+ GF L+ + K + + NG C +C C G+ G C D++EC N+ GC LC N GS CQC +G+ L ++K C++ S + + + + D K PG + + + P + + + V C G+ TC +L C C +RG+ +KC CP G+ G CE C H C+ + + CRC++ K ++ D N K DC +G+C C C G G+ C++ + C C N+EG + KC C PG+ H C+ +CS C G +CD C KC G+ G LCD C N + C H C NG+ SC C FY +T GR ++ C C+NG C N C+C PG++G C++ C C +C G + ECICPPG +TC C C NG C ++ C C G+ G C
Sbjct: 248 CEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAK----NNGCEHFCENV-KGTYRCKCREGYQLGRDGRTCEE----MLGGCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHD-INECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCH-DMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADIFSNDIEDYSK---VPGLDSIDEVISSIESY--PADESPRPLVFGRRRHVKECPNGF----FGSTC-QLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLK--CRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPH-FTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYY----GHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCD---QPCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCK--CQNGAICDTSNGSCECAPGWSGKKCDK---ACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKC 969 HSP 5 Score: 97.0561 bits (240), Expect = 4.881e-20 Identity = 162/612 (26.47%), Postives = 226/612 (36.93%), Query Frame = 1
Query: 823 VKSRCYCETGWFGERCVILEPELCKQR---KLLFCVHGCSFDKRKLDFSCICGIKETQNNCLEL-------RTCSK--GCQNGGTCFQ--GRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV-CQQI--CVNTIG----SYQCSCREGFT------LLSNGKCAINCLNNC----NKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD--KCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCK--------KLECPKCVRGTCNEN--KCKCPKGFAGLLCENDIN------------ECLNQTICQHV---CTNTIGSFFCRCK----NGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINE------CKKYSHICEHFCMNTEGSYKC-----------SCMPGFILSANSHSCQSVCSLCKNGKCDF-NNKCKCKTGWTGELCDVDI 2397
V C C +G+ G+ C PE K C+HG +K D CI G T +C L R C++ C+NG +C + GRC+C G+ G+ C+ SC G G + CE C EC + +SG+C C+ GW+GK CN + F C Q C N+ S +C C +G+ L +G +C C N D ++G C+C G G DC + ++ C LC C NGG+CD C CPPGYIG CE F C I CE+ T C CLPG+ M + C K +C +C G CN + +CKC GF G CE EC Q C V C G + RC+ NG +SC N C D +C+C +G++G +C++ +E C + + ++ C T+G C C PG SCQ+ C CD +C C GW G C +++
Sbjct: 1050 VTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCLCMHGGECNKENGDCECIDGW--TGPSCEFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCE---KSCVSGHYGAK-CEETC----------------------------ECENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLC-------------------------------SCENGGVCDSSTGSCVCPPGYIGTKCEIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTCNQVCPEGRFGAGCKEKC-RCANGHCNASSGECKCNLGFTGPSCEQSCPSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGAD--------GRCLCPAGFQGDKCEQKCSEGSFGPACSQQCNCGKYKCDATDGKCICPVGRHGPLCEEECRPGRY----GQSCQNKCQCFNGATCDARTGQCSCSPGWLGPTCQIEM 1583 HSP 6 Score: 94.3597 bits (233), Expect = 2.976e-19 Identity = 218/834 (26.14%), Postives = 316/834 (37.89%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICG--IKETQNNCLELRTCSK--GCQNGGTCFQG--RCQCTEGFE----GDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSC--IKE------ECSKFGTTEVVSGNCKCKQGW---KGKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLSNG-------KCAIN---CLNNC-NKNGDCLNGICYCFSGW---HGEDC-----------SLDIDECKYNHGCEHL--CVNVPGSFNCQCHSGFTLQINKKKCISK--------SCNI---ECLNGGLCDK------DKCKCPPGYIGHNCEFNDFC---HFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPK--------------CVRGTCNE--NKCKCPKGFAGLLCENDINECLNQTICQHVCT----NTIG----SFFCRCKNGHKLAEDKRSCIP-------PNKKTC---LDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGFILSANSH---------SCQSVCSLCKNGK-CDFNN-KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGR----------SCLEKNDS----------CSSPCKNGGKC--VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCM 2988
C H C+ + + C G + + +C+++ C+K GC++ +G RC+C EG++ G C+ + C Q+GN C+H C ++ + CKC++G+ L ND K C I E +CS+ S C+CK G+ K + +D+ EC C+QIC N G Y CSC GF L +G +C IN C C N+ G + C CF+G+ H E S DI++ G + + ++ S+ S L +++ + + +C + +C NGG C KC CP GY G CE C ++ C H C+ +C G D + C CP C G C+ C CP G G CE C+ C N+ G + CRCK G+ KR C P K +C + D V G C C +GY+G CD+ Y C H C G+ C C PGF + S C +C C+NG CD +N C+C GW+G+ CD C + S C C + DG C E DS CS C+NG C V C+C+PG+ G C+ + ++ GC C T N + P ++ D T + P C CP+G HG C +C A CD++ G C G C S G++CM
Sbjct: 291 CQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDGRTCEEMLGGC---QVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCHDMNECLINNGGCAQLCKNRKG---SRRCQCFAGYILAHDEKSCVAASDSADIFSNDIEDYSKVPGLDSIDEVISSIESYPAD-ESPRPLVFGRRRHVKECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCE--QICRNGYWGVDCAHKCSC----KLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKK---CPAGYQGNLCDQPCAP-NTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCK-CQNGAICDTSNGSCECAPGWSGKKCD----------KACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICS--CQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRF---GEGCNAICDCTTTNDTSMYNP-FVARCDHVTGECRCPAGWTGPDCQT----------SCPLGRHGEGCRHSC-QCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCM 1079 HSP 7 Score: 83.5741 bits (205), Expect = 6.363e-16 Identity = 203/816 (24.88%), Postives = 305/816 (37.38%), Query Frame = 1
Query: 802 CGEHGICVKSRCYCETGWFGERCVILEPELCKQRKL-LFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEIN---------------SCSRGQMGNRTCEHIC--VNEGEN-NFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQI---------CVNTIGSYQCSCREGFTL-LSNGKCAINCLN-NCNKNGDCLNGI--------CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSF------NCQCHSGFTLQINKKKC----ISKSCN--IECLNGGLCDKD--KCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTC--------------------KKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSF------FCRCKNGHKLAEDKRSCIPPN------KKTCLDKDCVH-GQC--FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGF---------ILSANSHSCQSVCSLCKNGK-CD-FNNKCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNG--SYSCSCNLPFYLSTVDGRSCLEK------NDSCSSPCKNGG----KCVNSKCKCKPGYNGDSCEEDINECQW-PISKHGCI----GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVC-RDMSRCYCPIGFHGIDC 2853
C G + S+C C +G+ GE+C ++C+ + C H CS +C C + CS G C +GF G QC L+ +C G G ++CE C G+N F CKC + +++G + ++G C+CK G+ G C LF + C G C G+ L + CA N NC C+NG C+C G++G CS ++ C LC G+ +C+C G++ + K C K C+ +C +G CD +C CPPG GH C+ F C I C++ T + C C PG+ + C + P R +C+CP G+ G C+ + C+H C + G+ FC C +G + ++ S P K CL C+H G+C N C C G+ G C E + ++ C C G+ +C C+PG+ + C+ C C+NG CD + C C+ GW G+ C+ + +H Q C NS S C P + G SC E +SCS C G ++ KC CKPG++G C+ + ++ P C G C ++ G+ C+CPPGY+ + CQ C +C NGG C R +C C GF G+ C
Sbjct: 603 CSMRGSGLLSKCDCPSGYTGEKCE----QICRNGYWGVDCAHKCSCK--------LCDPSTGSCRCEDPEKCSDG------------PCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYG-QSCEKPCPHFTFGKNCRFPCKCA---RENSEG-------------CDEITGKCRCKPGYYGHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQPCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCKCQNGAICDTSNGSCECAPGWSGKKCDKACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTNDTSMYNPFVARCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGF-MGKNCESECPEGLWGSNCMKHCL---CMHGGECNKENGDCECIDGWTGPSC-EFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCE-CENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYA---GHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCSCENGGVCDSSTGS--CVCPPGYIGTKCEIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTC 1366 HSP 8 Score: 79.7221 bits (195), Expect = 1.026e-14 Identity = 181/698 (25.93%), Postives = 253/698 (36.25%), Query Frame = 1
Query: 1024 CQNGGTC--FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHIC-----VNEGENNFQCKCQSGFQLDNDGKSCIKE----------ECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLF-PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSF------NCQCHSGFTLQINKKKC----ISKSCNIECL--NGGLCDKD--KCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIND------NMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHG-QCFNSK--------CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGF---------ILSANSHSCQSVCSLCKNGKCDFNN-KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNG------SYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVN-------SKCKCKPGYNGDSCEEDINECQWPISKHG--------CIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVCRDM-SRCYCPIGFHGIDC 2853
CQNG C G C+C G+ G +C +C+ G G + C C ++ ++ +C C G + ++C C T + V+G+C+C+ GW+GK C+ + F C IC T + T + N A D + G C C +GW G DC ++ GC H C G+ C C SGF + + +C +C CL +GG C+K+ C+C G+ G +CEF F F C C N C CLPG+ + C+K C G G CE + EC N +C + S C C+ G + + R C+ K + C +C NSK C C GY G C E + + C C E S KC C PG + C +CS G CD + C C G+ G C++ C+ C NG + C C LP + + C E + CK +C N +CKC G+ G SCE+ P K+G C G+ R C CPPG Q +C C+ C NG C RC CP GF G C
Sbjct: 859 CQNGAICDTSNGSCECAPGWSGKKCD---KACAPGTFG-KDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTND--------TSMYNPFVA---------RCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCLCMHGGECNKENGDCECIDGWTGPSCEFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGW----SGEHCEK----------------SCVSGHYGAKCE-ETCECENGALCDPI------SGHCSCQPGWRGKKCNRPCL----KGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPD-GTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCSCENGGVCDSSTGSCVCPPGYIGTKCEIACQSDRFGP-TCEKICNCENGGTCDRLTGQCRC-LPGFTGMTCNQVCPEGRF--GAGCKEKCRCANGHCNASSGECKCNLGFTGPSCEQSC-----PSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGADGRCLCPAGFQGDKC 1494 HSP 9 Score: 58.151 bits (139), Expect = 3.986e-8 Identity = 178/781 (22.79%), Postives = 260/781 (33.29%), Query Frame = 1
Query: 1060 QCTEGFEGDQCQLEINSCSRG------------------QMGNRTCEHICVNEGENNFQCKCQSGFQL-DNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVD-ECLFPVCQQI---CVNTIGSYQCSCREG---FTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNC---------QCHSGFTLQINKKKCISKSCNI------ECLNGGLCDKD--KCKCPPGYIGHNC-------EFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTC----------KKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFC----MNTEGSY------------KCSCMPGFI---------LSANSHSCQSVCSLCKNGKCD-FNNKCKCKTGWTGELCDVDIDECLLNQHKCQH----------------NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC--VNSKCKCKPGYNGDSCE------------EDINECQ-----WPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVCRDMS-RCYCPIGFHGIDC------GVDVDECQRY------APCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTM 2994
+C GF G CQL + C G CE IC N G C + +L D SC E+ K C G+ G CN +C C + C G Y SC + FT N + C ++ D + G C C G++G C + GC C + P C +C +G+ + + C + C+NG CD+ C C PG+ G C F C + C++ N C C PG+ K C KK +C + ++ +C CP G G C+ + L C+ +C+ C+NG TC D V G C C+ G+RGK+CD + ++ C C N Y +C C G+ L + C+ C CD C C +G+ G+ C+ + E L + +H C++ SC PF GR+C ++ + CKNG C +C+C PG++G+ CE E+ EC+ PIS H C C PG+ + C C+ C N C +S RC CP G+ G C G + C + + CD + G C+ G C S V G C +
Sbjct: 580 ECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRN-GYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDG-------PCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKRMCSPGLFGAGCAMKC-SCPAGIRCDPVTGDCTKKCPAGYQGNLCDQPCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCKCQNGAICDTSNGSCECAPGWSGKKCDKACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICS---------CQNG---------------ATC---DSVTG-----SCECRPGWRGKKCDRPCPD-GRFGEGCNAICDCTTTNDTSMYNPFVARCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCLCMHGGECNKENGDCECIDGWTGPSCEFLCPFGQF---GRNCAQRCN-----CKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCECENGALCDPISGH--------------CSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQL 1296
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Match: Y64G10A.7 (pep chromosome:WBcel235:IV:14291901:14319564:1 gene:WBGene00013416.1 transcript:Y64G10A.7a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y64G10A.7) HSP 1 Score: 139.813 bits (351), Expect = 3.500e-33 Identity = 142/458 (31.00%), Postives = 194/458 (42.36%), Query Frame = 1
Query: 1282 CKCKQGWKGKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKY-NHGCEHLCVNVPGSFNCQCHSGFTLQINKKKC--------ISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPC-------EHNCTTINDNMVCSCLPGYDLMPDKKTCKKL-ECPKC---------VRGTCNENKCKCPKGFA----GLLCENDINEC-LNQTICQHVCTNTI-GSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFN----SKCICKSGYR---GKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDS 2532
C+C G+ G C D +EC+ C+ CVNTIG+Y C C GF L +G N C+ DIDEC N GC CVN PG F C C S L + + C + C EC N + +C+C G+ E C + PC +H+CT + C C PG+ L D+++C + EC K V+GT +CKC +G+ G CE + C + CQH C + G C+C+NG+ LA D++ C N+ + DC C N +C CK G+R ++ EDI+EC + CE C N EG Y CSC PGF LS + HSC D++ECL+N C C N GS C C Y+ D +SC+ +DS
Sbjct: 141 CECPVGFTGAKCQYDANECMANNGGCEHECVNTIGTYYCRCWPGFELSGDG-------NTCS-----------------------DIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLS--ENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGT---YRCKCREGYQLGRDGRTCEEMLGGCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECHENNGDCSQ-ICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCH------------------------------DMNECLINNGGCAQLCKNRKGSRRCQC-FAGYILAHDEKSCVAASDS 531 HSP 2 Score: 130.568 bits (327), Expect = 2.724e-30 Identity = 146/451 (32.37%), Postives = 205/451 (45.45%), Query Frame = 1
Query: 1804 NMVCSCLPGYDLMPDKKTCKKLECPKCV---RGTC-------NENKCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGY----RGKRCDEDINECKKYSHICEHFCMNTEGS--YKCSCMPGFILSANSHSCQSVCSLCKN-GKCDFN-------NKCKCKTGWT---GELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGG---KCVNSK-----CKCKPGY---NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGV---DVDECQ-RYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAV 3006
+ V C PG+ P + C++ C + GTC NE C+CP GF G C+ D NEC+ N C+H C NTIG+++CRC G +L+ D +C ++ + C +C NS +C C S G+ C + + C + CEH C N Y+C C GF LS N SCQ V N G C + +C+C G+ VDIDEC N + C+H C N G+Y C C + L DGR+C E C NGG C + CKC+ GY N DINEC + C C N G+ EC C PG+ ++ D+KTC+ ++ + N C +C + C C GF + G D++EC C +L C N GS CQC + Y+L +D SC+ ++
Sbjct: 95 HTVAECCPGWVHRPGEAGCQRANCSADLCHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANECMANNGGCEHECVNTIGTYYCRCWPGFELSGDGNTCSDIDECAVSNGGCSD-RCVNSPGGFRCDCPSDLYLHADGRTCGK-VTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAKN-NGCEHFCENVKGTYRCKCREGYQLGR-DGRTCEEMLGGCQV--GNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECHE--NNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQ--ICSNQEGGYMCSCEPGFELSEDGHSCHDMNECLINNGGCAQL---CKNRKGSRRCQCFAGYILAHDEKSCVAASDSA 532 HSP 3 Score: 129.028 bits (323), Expect = 8.612e-30 Identity = 209/771 (27.11%), Postives = 285/771 (36.96%), Query Frame = 1
Query: 1024 CQNGGTCFQGR-------CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNC--KCKQGWKGKFCNDDVDECLFP----------------VCQQICVNTIGS--YQCSCREGFTLLSN--------------GKCAINCLNNCNKNGDCLNGICYCFSGWH---GEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD---------KCKCPPGYIGHNCEFNDFCHFISPCEHN-------CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNE--------NKCKCPKGFA----GLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRG-KRCDEDINECKKY-SHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKN-GKCDFN-----NKCKCKTGWTGE----------------------LCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGR--------SCLEK--NDSCSSPCKN---GGKC----------------VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGY----LVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCG-----VDVDECQRYAPCDKLRGIC 2913
C NGGTC C+C GF G +CQ + N C N CEH CVN + C+C GF+L DG + CS V +G C +C G C+ D L C+ C N Y+C CR GF L N G C +C NN + C C+ G+H +DIDEC N+GCEH C NV G++ C+C G+ L + + C + NGG C D CKC GYI N CH I+ C N C + ++ C C PG+ LM D+KTC+ + G C + C C GF G C +D+NECL N C +C N GS C+C G+ LA D++SC+ + + F++ S G DE I+ + Y + + + C GF S +CQ CS C+N GKC +KC C +G+TGE LCD C + + +G Y CNL + +GR +C + SC PC + G C + KC+CKPGY G C+ C + GC +C CP G + D K C + +C+ CP G+ G DC DV + C + G C
Sbjct: 123 CHNGGTCVPSEHNDNEQVCECPVGFTGAKCQYDANEC---MANNGGCEHECVNT-IGTYYCRCWPGFELSGDGNT-----CSDIDECAVSNGGCSDRCVNSPGGFRCDCPSDLYLHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGR------AQCQCYPGFHLSYDRRSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDGRTCEEMLGGCQVGNGG-CQHDCYDQPDGGHVCKCRNGYILAN--DQKLCHDINECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSC-HDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADI---------FSNDIEDYSKVPGLDSIDEVISSIESYPADESPRPLVFGRRRHVKECPNGFFGS----TCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKR---MCSPGLFGAGCA---------MKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQP--------------CPAGYFGYDCEQKCSCADVASPHKSKVCHHVTGTC 835 HSP 4 Score: 97.0561 bits (240), Expect = 4.305e-20 Identity = 166/629 (26.39%), Postives = 233/629 (37.04%), Query Frame = 1
Query: 823 VKSRCYCETGWFGERCVILEP-----ELCKQRKLLFCVHGCSFDKRKLDFSCICGI--KETQNNCLE-------LRTCSKGCQNGGTCFQ--GRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHIC-----VNEGENNFQCKCQSGFQLDNDGKSCIKE----------ECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV-CQQI--CVNTIG----SYQCSCREGFT------LLSNGKCAINCLNNC----NKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD--KCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCK--------KLECPKCVRGTCNEN--KCKCPKGFAGLLCENDIN------------ECLNQTICQHV---CTNTIGSFFCRCK----NGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINE------CKKYSHICEHFCMNTEGSYKC-----------SCMPGFILSANSHSCQSVCSLCKNGKCDF-NNKCKCKTGWTGELCDVDI 2397
V C C GW G C P E C R C +G S D+ C G K ++ C E ++ C C +GG C + G C+C +G+ G C+ C GQ G R C C + +C+C G+ ++ KSC+ EC + +SG+C C+ GW+GK CN + F C Q C N+ S +C C +G+ L +G +C C N D ++G C+C G G DC + ++ C LC C NGG+CD C CPPGYIG CE F C I CE+ T C CLPG+ M + C K +C +C G CN + +CKC GF G CE EC Q C V C G + RC+ NG +SC N C D +C+C +G++G +C++ +E C + + ++ C T+G C C PG SCQ+ C CD +C C GW G C +++
Sbjct: 1056 VTGECRCPAGWTGPDCQTSCPLGRHGEGC--RHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCL--CMHGGECNKENGDCECIDGWTGPSCEF---LCPFGQFG-RNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCECENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLC-------------------------------SCENGGVCDSSTGSCVCPPGYIGTKCEIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTCNQVCPEGRFGAGCKEKC-RCANGHCNASSGECKCNLGFTGPSCEQSCPSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGAD--------GRCLCPAGFQGDKCEQKCSEGSFGPACSQQCNCGKYKCDATDGKCICPVGRHGPLCEEECRPGRY----GQSCQNKCQCFNGATCDARTGQCSCSPGWLGPTCQIEM 1632 HSP 5 Score: 93.5893 bits (231), Expect = 6.183e-19 Identity = 211/793 (26.61%), Postives = 311/793 (39.22%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGI----KETQNNCLELRTC---SKGCQNGGTCFQGR--CQCTEGFE---GDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNC--------------KCKQGW----KGKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCL--------NGICYCFSGWH----GEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTI---NDNMVCSCLPGYDLMPDKKTCKKLECPKC-------VRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTI---GSFFCRCKNGHKLAE----DKRSCIPPNKKTCLDKDCVHGQC--FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCM----NTEG----SYKCSCMPGFILSANSHSCQSVCS------------LCKNG-KCD-FNNKC--KCKTGWTGELCDVDIDECLLNQHKCQHNC------------VNSNGSYSCSCNLPFYLSTVDGRSCLE----KNDSCSSPCKNGGKCVNS--KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFG------NYECICPPGYLVLDDQKTCQISTKDTMCNPH--CLNGGVCRDM-SRCYCPIGFHGIDCGVDVD------------ECQRYAPCDKLRGIC 2913
C H C D + C C + E + +C + C GCQ+ T GR CQC GF + ++I+ C++ N CEH C N + ++CKC+ G+QL DG++C + G +V +G C KC+ G+ K C+D ++EC C QICVN GS +C C+ GF L+ + K + + NG C +C C G+ G C D++EC N+ GC LC N GS CQC +G+ L ++K C++ S + + + + D K PG + + + P + + + V C G+ TC +L C C +RG+ +KC CP G+ G CE C H C+ + + CRC++ K ++ D N K DC +G+C C C G G+ C++ + C C N+EG + KC C PG+ H C+ +CS C G +CD C KC G+ G LCD + C+ C V + + +C+C LP + +SC N + + C NG KC S C C PG+ G +C E ++ I C+ C+ G N C C PG+ K C T C+ C +G C C CP G G C D CQ A CD + G C
Sbjct: 248 CEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNNHGRAQCQCYPGFHLSYDRRSCVDIDECAK----NNGCEHFCENV-KGTYRCKCREGYQLGRDGRTCEE----MLGGCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHD-INECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGHSCH-DMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADIFSNDIEDYSK---VPGLDSIDEVISSIESY--PADESPRPLVFGRRRHVKECPNGF----FGSTC-QLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLK--CRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPH-FTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYY----GHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQPCPAGYFG-YDCEQKCSCADVASPHKSKVCHHVTGTCTC-LPGKTGPLCDQSCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGID---CMQLCKCQNGAICDTSNGSCECAPGWSGKKCDKACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSC 1007 HSP 6 Score: 82.8037 bits (203), Expect = 1.151e-15 Identity = 207/850 (24.35%), Postives = 314/850 (36.94%), Query Frame = 1
Query: 802 CGEHGICVKSRCYCETGWFGERCVILEPELCKQRKL-LFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEIN---------------SCSRGQMGN---RTCEHI-----------CVNEG-----ENNFQCKCQSGFQLDNDGKSC----------IKEECSKFGTTEVVSGNC--KCKQGWKGKFCNDDVDECLF---------------PVCQQICVNTIGSYQCSCREGFT-LLSNGKCAINCLN-NCNKNGDCLNGI--------CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSF------NCQCHSGFTLQINKKKC----ISKSCN--IECLNGGLCDKD--KCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTC--------------------KKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSF------FCRCKNGHKLAEDKRSCIPPN------KKTCLDKDCVH-GQC--FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGF---------ILSANSHSCQSVCSLCKNGK-CD-FNNKCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNG--SYSCSCNLPFYLSTVDGRSCLEK------NDSCSSPCKNGG----KCVNSKCKCKPGYNGDSCEEDINECQW-PISKHGCI----GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVC-RDMSRCYCPIGFHGIDC 2853
C G + S+C C +G+ GE+C ++C+ + C H CS +C C + CS G C +GF G QC L+ +C G G + C H C E E +C+C+ G+ + + C +K C + V+G+C KC G++G C+ F P ++C + G+ C+C G T L + CA N NC C+NG C+C G++G CS ++ C LC G+ +C+C G++ + K C K C+ +C +G CD +C CPPG GH C+ F C I C++ T + C C PG+ + C + P R +C+CP G+ G C+ + C+H C + G+ FC C +G + ++ S P K CL C+H G+C N C C G+ G C E + ++ C C G+ +C C+PG+ + C+ C C+NG CD + C C+ GW G+ C+ + +H Q C NS S C P + G SC E +SCS C G ++ KC CKPG++G C+ + ++ P C G C ++ G+ C+CPPGY+ + CQ C +C NGG C R +C C GF G+ C
Sbjct: 603 CSMRGSGLLSKCDCPSGYTGEKCE----QICRNGYWGVDCAHKCSCK--------LCDPSTGSCRCEDPEKCSDG------------PCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKRMCSPGLFGAGCAMKCSCPAGIRCDPVTGDCTKKCPAGYQGNLCDQPCPAGYFGYDCEQKCSCADVASPHKSKVCHHVTGT--CTCLPGKTGPLCDQSCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCKCQNGAICDTSNGSCECAPGWSGKKCDKACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTNDTSMYNPFVARCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGF-MGKNCESECPEGLWGSNCMKHCL---CMHGGECNKENGDCECIDGWTGPSC-EFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCE-CENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYA---GHSCTELCPDGTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCSCENGGVCDSSTGS--CVCPPGYIGTKCEIACQSDRFGPTCEKICNCENGGTCDRLTGQCRCLPGFTGMTC 1415 HSP 7 Score: 79.7221 bits (195), Expect = 9.259e-15 Identity = 180/697 (25.82%), Postives = 251/697 (36.01%), Query Frame = 1
Query: 1024 CQNGGTC--FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEG----ENNFQCKCQSGFQLDNDGKSCIKE----------ECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLF-PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSF------NCQCHSGFTLQINKKKC----ISKSCNIECL--NGGLCDKD--KCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIND------NMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHG-QCFNSK--------CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGF---------ILSANSHSCQSVCSLCKNGKCDFN-NKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNG------SYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVN-------SKCKCKPGYNGDSCEEDINECQWPISKHG--------CIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVCRDM-SRCYCPIGFHGIDC 2853
CQNG C G C+C G+ G +C +C+ G G + +G ++ +C C G + ++C C T + V+G+C+C+ GW+GK C+ + F C IC T + T + N A D + G C C +GW G DC ++ GC H C G+ C C SGF + + +C +C CL +GG C+K+ C+C G+ G +CEF F F C C N C CLPG+ + C+K C G G CE + EC N +C + S C C+ G + + R C+ K + C +C NSK C C GY G C E + + C C E S KC C PG + C +CS G CD + C C G+ G C++ C+ C NG + C C LP + + C E + CK +C N +CKC G+ G SCE+ P K+G C G+ R C CPPG Q +C C+ C NG C RC CP GF G C
Sbjct: 908 CQNGAICDTSNGSCECAPGWSGKKCD---KACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTND--------TSMYNPFVA---------RCDHVTGECRCPAGWTGPDCQTSCPLGRHGEGCRHSCQCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCLCMHGGECNKENGDCECIDGWTGPSCEFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGW----SGEHCEK----------------SCVSGHYGAKCE-ETCECENGALCDPI------SGHCSCQPGWRGKKCNRPCL----KGYFGRHCSQSCRCANSKSCDHISGRCQCPKGYAGHSCTELCPD-GTFGESCSQKCDCGENSMCDAISGKCFCKPGHSGSDCKSGCVQGRFGPDCNQLCSCENGGVCDSSTGSCVCPPGYIGTKCEIACQSDRFGP-TCEKICNCENGGTCDRLTGQCRC-LPGFTGMTCNQVCPEGRF--GAGCKEKCRCANGHCNASSGECKCNLGFTGPSCEQSC-----PSGKYGLNCTLDCECYGQARCDPVQGCCDCPPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGADGRCLCPAGFQGDKC 1543 HSP 8 Score: 70.0922 bits (170), Expect = 9.368e-12 Identity = 194/763 (25.43%), Postives = 256/763 (33.55%), Query Frame = 1
Query: 1054 RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEE--------CSKFGTTEVVSGNCKCKQGW---------------KGKFCNDDVDECLFPVCQQI--CVNTIGSYQC----------------SCREGFTLLSNGKCAINCLNN--CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH-----LCVNVPGSFNCQ---------CHSGF-TLQINKKKCISKSCNIECLNGGLCDK--DKCKCPPGYIGHNCE-------FNDFCHFISPCEHNCTTINDNMV--CSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQ-------TICQHVCTNTIGSFFCRCKNGHKLAEDKRSCI---PPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGFILSANSH---------SCQSVCSLCKNGK-CDFNN-KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGR----------SCLEKNDS----------CSSPCKNGGKC--VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCM 2988
CQC GF + + S N CE IC N+ E + C C+ GF+L DG SC C++ S C+C G+ F ND D P I +++I SY C GF + +C N C+ G L C C SG+ GE C + C H LC GS C+ C GF Q N K C ++C NG CD C CP G G +CE F C F C + D + C C PGY CK++ P C KC CP AG+ C+ +C + +C C + C E K SC P+K K C H C C G G CD+ Y C H C G+ C C PGF + S C +C C+NG CD +N C+C GW+G+ CD C + S C C + DG C E DS CS C+NG C V C+C+PG+ G C+ + ++ GC C T N + P ++ D T + P C CP+G HG C +C A CD++ G C G C S G++CM
Sbjct: 427 ECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICSNQ-EGGYMCSCEPGFELSEDGHSCHDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAASDSADIFSNDIEDYSKVPGLDSIDEVISSIESYPADESPRPLVFGRRRHVKECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRNGYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDGPCPDGFYGSQCNLK------CRMDCPNG-RCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYY----GHHCKRMCSPGLFGAGC-AMKCSCP---AGIRCDPVTGDCTKKCPAGYQGNLCDQPCPAGYFGYDC---------EQKCSCADVASPHKS----KVCHH---VTGTCTCLPGKTGPLCDQSCAP-NTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCK-CQNGAICDTSNGSCECAPGWSGKKCD----------KACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDSGLFGAGCKGICS--CQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRF---GEGCNAICDCTTTNDTSMYNP-FVARCDHVTGECRCPAGWTGPDCQT----------SCPLGRHGEGCRHSC-QCSNGASCDRVTGFCDCPSGFMGKNCESECPEGLWGSNCM 1128 HSP 9 Score: 61.6178 bits (148), Expect = 3.034e-9 Identity = 177/741 (23.89%), Postives = 250/741 (33.74%), Query Frame = 1
Query: 1060 QCTEGFEGDQCQLEINSCSRG------------------QMGNRTCEHICVNEGENNFQCKCQSGFQL-DNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVD-ECLFPVCQQI---CVNTIGSYQCSCREG---FTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPG-YDLMPDKKTCKKLECPKCVR-------GTCNEN--KCKCPKGFAGLLCENDIN------ECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPN-----KKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSY------KCSCMPGFIL---------SANSHSCQSVCSLCKN----------GKCD-FNNKCKCKTGWTGELCDVDIDECLLNQH--KCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWP-------ISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP--HCLNGGVC-RDMSRCYCPIGFHGIDC---------GVDVD---ECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC 2985
+C GF G CQL + C G CE IC N G C + +L D SC E+ K C G+ G CN +C C + C G Y SC + FT N + C ++ D + G C C G++G C + GC + C C +G C K G LCD+ CP GY G++CE C ++ + + C+CLPG + D+ P C C+E+ C C GF G C +C+ CQ+ +C + GS C C G + ++C P K C D +H + +CIC G +G +CDE + + C+ C G+ C C PG+ C ++C +CD +C+C GWTG C C L +H C+H+C SNG+ SC+ V C C G+ G +CE + E W + HG GEC G+ ECI G+ + C C +C NG C R RC C G+ G C G + EC+ A CD + G C G +C+ + Y G C
Sbjct: 580 ECPNGFFGSTCQLSCSDCQNGGKCSMRGSGLLSKCDCPSGYTGEKCEQICRN-GYWGVDCAHKCSCKLCDPSTGSCRCEDPEKCSDG-------PCPDGFYGSQCNLKCRMDCPNGRCDPVFGYCTCPDGLYGQSCEKPCPHFTFGKNCRFPCKCARENSEGCDEITGKCRCKPGYYGHHCKRMCSPGLFGAGC---------AMKCSCPAGIRCDPVTGDCTKKC--PAGYQGNLCDQ---PCPAGYFGYDCEQKCSCADVASPHKSKVCHHVTGTCTCLPGKTGPLCDQSCAPNTYGPNCAHTCSCVNGAKCDESDGSCHCTPGFYGATCSEVCPTGRFGIDCMQLCKCQNGAICDTSNGS--CECAPGWSGKKCDKACAPGTFGKDCSKKCDCADGMHCDPSDGECICPPGKKGHKCDETCDS-GLFGAGCKGICSCQNGATCDSVTGSCECRPGWRGKKCDRPCPDGRFGEGCNAICDCTTTNDTSMYNPFVARCDHVTGECRCPAGWTGPDCQT---SCPLGRHGEGCRHSCQCSNGA---SCDR-----------------------------VTGFCDCPSGFMGKNCESECPEGLWGSNCMKHCLCMHG--GECNKENGDCECI--DGWTGPSCEFLCPFGQFGRNCAQRCNCKNGASCDRKTGRCECLPGWSGEHCEKSCVSGHYGAKCEETCECENGALCDPISGHCSCQPGWRGKKCNRPCLKGYFGRHC 1256
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Match: N (gene:FBgn0004647 transcript:FBtr0304659) HSP 1 Score: 207.994 bits (528), Expect = 3.163e-54 Identity = 260/894 (29.08%), Postives = 347/894 (38.81%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHG--CSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECL---FPVCQ--QICVNTIGSYQCSCREGFTLL-------------------------------SNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIE----------------------------------CLNGGLCDKD----KCKCPPGYIGHNCEFN-DFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTC----NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHK-------------------------LAEDKRSCIP--------PNKKTCLDKDCVH-GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN---------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS------KCKCKPGYNGDSCEEDINECQWPIS-KHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
C C G+ GERC LC C +G C+ F+C C T + C ++ C S C+ GGTC +C C G+ G C + CS N IC + G + ++CKC GF+ N + C+ C GT + C+C + G+FC DDVDEC PVCQ C NT GSY C C G+ L + GK + C N C+ + C +NG C C +G+ G DCS DIDEC CEH +CVN PGS+ C C GFT + N +C S C E CLN G C KC C G+ G C+ N D C PC + C C C PGY + + C RG C N KC C G+ G +C+ INEC CQ C + +GS++C+C+ G + K C+P N C+ C + G C + KC C G+ C D++EC + E C + + C C PG+ C+ C + C C+C G+TG+ C+ +ID+C+ N C++ Y C C +PF GR C K D C+S CKN KC S C CK GY G C+EDI+EC ++G C N G+Y C+C GY + + C I+T D P C NGG C D C C GF G C D++EC PC C S+ C C L + G +C T E
Sbjct: 164 CACANGYTGERCET--KNLCASSP---CRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEECQSNPCKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKPCSPSPCQNGG---ICRSNGLS-YECKCPKGFEGKNCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICVNGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSPINGSYACSCATGYKGVDCSEDIDECDQGSPCEHNGICVNTPGSYRCNCSQGFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKINGFKCSCALGFTGARCQINIDDCQS-QPCRNRGICHDSIAGYSCECPPGYTGTSCEININDCDSNPCHRGKCIDDVNSFKCLCDPGYTGYICQKQINEC-ESNPCQFDGHCQDRVGSYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCVPGFTGQHCEKNVDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGINEFICHCPPGYT----GKRCELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCKVPFT-----GRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNG--ASCLNVPGSYRCLCTKGY----EGRDCAINTDDCASFP-CQNGGTCLDGIGDYSCLCVDGFDGKHCETDINECLS-QPCQN-GATCSQYVNSYTCTCP----LGFSGINCQTNDE 1024 HSP 2 Score: 170.629 bits (431), Expect = 1.952e-42 Identity = 230/789 (29.15%), Postives = 331/789 (41.95%), Query Frame = 1
Query: 973 IKETQNNCLELRTCSKGCQNGGTCF-----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-------QLDN--DGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQI--NKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDL---MPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHK----LAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCS--------------------------------------CMPGFILSA---NSHSCQSVCSLCKNGKC-DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGNKGVTKVI 3063
++ T + S GCQNGGTC + C C + GD C+ N C+ + N + G CKC GF + N D +C+ + T E + C C G+ G+ C + +C ++ CR G T C + C C G+ G+ CS DI+EC+ N C++ CVN GS+ C C +G+T + K K S S C NGG+C + +CKCP G+ G NCE N C++ T I+ + C C P + D C + + P C G T C C G+AGL C N+ ++C Q C + C + +GSF+C+C G +D + P + D ++G + C C +GY+G C EDI+EC + S CEH C+NT GSY+C+ CMPGF + + CQS L +G C D N KC C G+TG C ++ID+C + + C +S YSC C P Y G SC + ND S+PC GKC++ KC C PGY G C++ INEC+ + G C++ G+Y C C G K C+++ + NP C NG C D +C C GF G C +VDEC +PC G+C + + C+C + YD + E P + GR G+ + I
Sbjct: 50 VRGTDTALVAASCTSVGCQNGGTCVTQLNGKTYCACDSHYVGDYCEHR-NPCNSMRCQNGGTCQVTFRNGRPGISCKCPLGFDESLCEIAVPNACDHVTCLNGGTCQLKTLEEYT--CACANGYTGERCET----------KNLCASS------PCRNGAT--------------CTALAGSSSFTCSCPPGFTGDTCSYDIEECQSNP-CKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKPCSPS---PCQNGGICRSNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICVNGWAGLDCSNNTDDC-KQAACFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSPING---SYACSCATGYKGVDCSEDIDECDQGS-PCEHNGICVNTPGSYRCNCSQGFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCL-NDGTCHDKINGFKCSCALGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCEC-PPGYT----GTSCEININDCDSNPCHR-GKCIDDVNSFKCLCDPGYTGYICQKQINECESNPCQFD--GHCQDRVGSYYCQCQAGT----SGKNCEVNVNECHSNP-CNNGATCIDGINSYKCQCVPGFTGQHCEKNVDECIS-SPCAN-NGVCIDQVNGYKCECPRGF---YDAHCLSDVDECASNPCVN-EGRCEDGINEFI 776 HSP 3 Score: 163.31 bits (412), Expect = 3.044e-40 Identity = 209/757 (27.61%), Postives = 317/757 (41.88%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFC-VHGCSFD----KRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-------QLDN-DGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN----CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGS----FNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVRGT-----CNENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF---ILSANSHSCQ--------SVCSLCKNGKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKC----VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCR-----DMSRCYCPIGFHGIDCGVDVDECQRYAPC 2892
+C C+ G+ G C Q+++ C + C FD R + C C + NC + + C S C NG TC G +CQC GF G C+ ++ C N +C+++ N ++C+C GF +D C+ E + G E + C C G+ GK C D+DEC CQ C + + ++ C C G+T KC N N C G C++ + C C + G DC +D C N C++ P S F+C C G+T + + S + C NG C +C C GY G +C N D C PC++ T ++ + C C+ G+D + + C G N C CP GF+G+ C+ + +C + + C + I + C C G+ A + + CL+ H Q C C SG+ GK+C E ++ C + C + + C C G+ + + SCQ S+ LC NG C D+ N C C G+ G C +IDEC + C + G+Y C C F G++C L +D +PC+NGG C +N C C PG G CE + ++C+ P + H G C + G +EC+C PG++ C+ + + NP C N G + C C G G C VD C + +PC
Sbjct: 624 KCLCDPGYTGYIC---------QKQINECESNPCQFDGHCQDRVGSYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCVPGFTGQHCEKNVDECISSPCANNG---VCIDQ-VNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGINEFI---CHCPPGYTGKRCELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYT---GQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCKVPFTGRDCESKMDPCASNR-CKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTKGYEGRDCAINTDDCASF-PCQNGGTCLDGIGDYSCLCVDGFDGKHCETDINECLSQPCQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSCLNGGSCIDGINGYNCSCLAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCPSGFTGKQCSEYVDWCGQSPCENGATCSQMKHQFSCKCSAGWTGKLCDVQTISCQDAADRKGLSLRQLCNNGTCKDYGNSHVCYCSQGYAGSYCQKEIDECQSQPCQNGGTCRDLIGAYECQCRQGF-----QGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCK-PGACHN-NGSCIDRVGGFECVCQPGFV----GARCEGDINECLSNP-CSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDFCAQ-SPC 1346 HSP 4 Score: 162.155 bits (409), Expect = 6.363e-40 Identity = 210/757 (27.74%), Postives = 324/757 (42.80%), Query Frame = 1
Query: 781 IDNCVPD-CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-------QLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDEC-LFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLN----NCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSC----------------------------------NIECLNGGLCDKD----KCKCPPGYIGHNC-EFNDFCHFISPCEH--NCTTINDNMVCSCLPGY-----DLMP----DKKTCKKLECPK-CVRGTC----NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE---DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDF-----------NNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVNS-----KCKCKPGYNGDSCEED-INECQWPISKHGCIGECRNTFGNYECICP 2709
+D C+ C +G+C+ +C C G++ C+ E CV+ + +F C C T C L++ CS CQ+GGTC+ CQC G+ G +C+ I+ C GN C+++ N ++C C+ F ++D + K E ++ + +C CK G+ G++C++D+DEC L C+ C+N GSY+C C +G+ CAIN + C G CL+GI C C G+ G+ C DI+EC + C++ C S+ C C GF+ Q N + C SC + CLNG C + C CP G+ G C E+ D+C SPCE+ C+ + C C G+ D+ D K L + C GTC N + C C +G+AG C+ +I+EC +Q CQ+ C + IG++ C+C+ G + + C P C + H + N C C G G C+ + ++CK + C++ G ++C C PGF+ + C+ + C + C N C C+ G G C+ +D C Q CQ+ NC + C CN FY G++C L D S+PC+ G V +C+C G G+ CE D ++EC G C + G+YEC+CP
Sbjct: 716 VDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNP----CVNEGRCEDGINEFICHCPPGYTGKRCELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGG---TCIDK-VNGYKCVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTKGY---EGRDCAINTDDCASFPCQNGGTCLDGIGDYSCLCVDGFDGKHCETDINEC-LSQPCQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSCLNGGSCIDGINGYNCSCLAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCPSGFTGKQCSEYVDWCG-QSPCENGATCSQMKHQFSCKCSAGWTGKLCDVQTISCQDAADRKGLSLRQLCNNGTCKDYGNSHVCYCSQGYAGSYCQKEIDECQSQP-CQNGGTCRDLIGAYECQCRQGFQGQNCELNIDDCAP---NPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCKPGACHNNGSCIDRVGGFECVCQPGFVGA----RCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDFCA--QSPCQNGGNCNIRQSGHHCICNNGFY-----GKNCELSGQDCDSNPCRVGNCVVADEGFGYRCECPRGTLGEHCEIDTLDECSPNPCAQG--AACEDLLGDYECLCP 1442
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Match: N (gene:FBgn0004647 transcript:FBtr0070507) HSP 1 Score: 207.994 bits (528), Expect = 3.163e-54 Identity = 260/894 (29.08%), Postives = 347/894 (38.81%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHG--CSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECL---FPVCQ--QICVNTIGSYQCSCREGFTLL-------------------------------SNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIE----------------------------------CLNGGLCDKD----KCKCPPGYIGHNCEFN-DFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTC----NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHK-------------------------LAEDKRSCIP--------PNKKTCLDKDCVH-GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN---------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS------KCKCKPGYNGDSCEEDINECQWPIS-KHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
C C G+ GERC LC C +G C+ F+C C T + C ++ C S C+ GGTC +C C G+ G C + CS N IC + G + ++CKC GF+ N + C+ C GT + C+C + G+FC DDVDEC PVCQ C NT GSY C C G+ L + GK + C N C+ + C +NG C C +G+ G DCS DIDEC CEH +CVN PGS+ C C GFT + N +C S C E CLN G C KC C G+ G C+ N D C PC + C C C PGY + + C RG C N KC C G+ G +C+ INEC CQ C + +GS++C+C+ G + K C+P N C+ C + G C + KC C G+ C D++EC + E C + + C C PG+ C+ C + C C+C G+TG+ C+ +ID+C+ N C++ Y C C +PF GR C K D C+S CKN KC S C CK GY G C+EDI+EC ++G C N G+Y C+C GY + + C I+T D P C NGG C D C C GF G C D++EC PC C S+ C C L + G +C T E
Sbjct: 164 CACANGYTGERCET--KNLCASSP---CRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEECQSNPCKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKPCSPSPCQNGG---ICRSNGLS-YECKCPKGFEGKNCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICVNGWAGLDCSNNTDDCKQAACFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSPINGSYACSCATGYKGVDCSEDIDECDQGSPCEHNGICVNTPGSYRCNCSQGFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGTCHDKINGFKCSCALGFTGARCQINIDDCQS-QPCRNRGICHDSIAGYSCECPPGYTGTSCEININDCDSNPCHRGKCIDDVNSFKCLCDPGYTGYICQKQINEC-ESNPCQFDGHCQDRVGSYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCVPGFTGQHCEKNVDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGINEFICHCPPGYT----GKRCELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCKVPFT-----GRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNG--ASCLNVPGSYRCLCTKGY----EGRDCAINTDDCASFP-CQNGGTCLDGIGDYSCLCVDGFDGKHCETDINECLS-QPCQN-GATCSQYVNSYTCTCP----LGFSGINCQTNDE 1024 HSP 2 Score: 170.629 bits (431), Expect = 1.952e-42 Identity = 230/789 (29.15%), Postives = 331/789 (41.95%), Query Frame = 1
Query: 973 IKETQNNCLELRTCSKGCQNGGTCF-----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-------QLDN--DGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQI--NKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDL---MPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHK----LAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCS--------------------------------------CMPGFILSA---NSHSCQSVCSLCKNGKC-DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGNKGVTKVI 3063
++ T + S GCQNGGTC + C C + GD C+ N C+ + N + G CKC GF + N D +C+ + T E + C C G+ G+ C + +C ++ CR G T C + C C G+ G+ CS DI+EC+ N C++ CVN GS+ C C +G+T + K K S S C NGG+C + +CKCP G+ G NCE N C++ T I+ + C C P + D C + + P C G T C C G+AGL C N+ ++C Q C + C + +GSF+C+C G +D + P + D ++G + C C +GY+G C EDI+EC + S CEH C+NT GSY+C+ CMPGF + + CQS L +G C D N KC C G+TG C ++ID+C + + C +S YSC C P Y G SC + ND S+PC GKC++ KC C PGY G C++ INEC+ + G C++ G+Y C C G K C+++ + NP C NG C D +C C GF G C +VDEC +PC G+C + + C+C + YD + E P + GR G+ + I
Sbjct: 50 VRGTDTALVAASCTSVGCQNGGTCVTQLNGKTYCACDSHYVGDYCEHR-NPCNSMRCQNGGTCQVTFRNGRPGISCKCPLGFDESLCEIAVPNACDHVTCLNGGTCQLKTLEEYT--CACANGYTGERCET----------KNLCASS------PCRNGAT--------------CTALAGSSSFTCSCPPGFTGDTCSYDIEECQSNP-CKYGGTCVNTHGSYQCMCPTGYTGKDCDTKYKPCSPS---PCQNGGICRSNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTCIDGISDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNTHGSYSCICVNGWAGLDCSNNTDDC-KQAACFYGATCIDGVGSFYCQCTKGKTGLLCHLDDACTSNPCHADAICDTSPING---SYACSCATGYKGVDCSEDIDECDQGS-PCEHNGICVNTPGSYRCNCSQGFTGPRCETNINECESHPCQNEGSCLDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCL-NDGTCHDKINGFKCSCALGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCEC-PPGYT----GTSCEININDCDSNPCHR-GKCIDDVNSFKCLCDPGYTGYICQKQINECESNPCQFD--GHCQDRVGSYYCQCQAGT----SGKNCEVNVNECHSNP-CNNGATCIDGINSYKCQCVPGFTGQHCEKNVDECIS-SPCAN-NGVCIDQVNGYKCECPRGF---YDAHCLSDVDECASNPCVN-EGRCEDGINEFI 776 HSP 3 Score: 163.31 bits (412), Expect = 3.044e-40 Identity = 209/757 (27.61%), Postives = 317/757 (41.88%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFC-VHGCSFD----KRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-------QLDN-DGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN----CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGS----FNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVRGT-----CNENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF---ILSANSHSCQ--------SVCSLCKNGKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKC----VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCR-----DMSRCYCPIGFHGIDCGVDVDECQRYAPC 2892
+C C+ G+ G C Q+++ C + C FD R + C C + NC + + C S C NG TC G +CQC GF G C+ ++ C N +C+++ N ++C+C GF +D C+ E + G E + C C G+ GK C D+DEC CQ C + + ++ C C G+T KC N N C G C++ + C C + G DC +D C N C++ P S F+C C G+T + + S + C NG C +C C GY G +C N D C PC++ T ++ + C C+ G+D + + C G N C CP GF+G+ C+ + +C + + C + I + C C G+ A + + CL+ H Q C C SG+ GK+C E ++ C + C + + C C G+ + + SCQ S+ LC NG C D+ N C C G+ G C +IDEC + C + G+Y C C F G++C L +D +PC+NGG C +N C C PG G CE + ++C+ P + H G C + G +EC+C PG++ C+ + + NP C N G + C C G G C VD C + +PC
Sbjct: 624 KCLCDPGYTGYIC---------QKQINECESNPCQFDGHCQDRVGSYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINSYKCQCVPGFTGQHCEKNVDECISSPCANNG---VCIDQ-VNGYKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGINEFI---CHCPPGYTGKRCELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYT---GQKCETNIDDCVTNPCGNGGTCIDKVNGYKCVCKVPFTGRDCESKMDPCASNR-CKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTKGYEGRDCAINTDDCASF-PCQNGGTCLDGIGDYSCLCVDGFDGKHCETDINECLSQPCQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSCLNGGSCIDGINGYNCSCLAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCPSGFTGKQCSEYVDWCGQSPCENGATCSQMKHQFSCKCSAGWTGKLCDVQTISCQDAADRKGLSLRQLCNNGTCKDYGNSHVCYCSQGYAGSYCQKEIDECQSQPCQNGGTCRDLIGAYECQCRQGF-----QGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCK-PGACHN-NGSCIDRVGGFECVCQPGFV----GARCEGDINECLSNP-CSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDFCAQ-SPC 1346 HSP 4 Score: 162.155 bits (409), Expect = 6.363e-40 Identity = 210/757 (27.74%), Postives = 324/757 (42.80%), Query Frame = 1
Query: 781 IDNCVPD-CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-------QLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDEC-LFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLN----NCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSC----------------------------------NIECLNGGLCDKD----KCKCPPGYIGHNC-EFNDFCHFISPCEH--NCTTINDNMVCSCLPGY-----DLMP----DKKTCKKLECPK-CVRGTC----NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE---DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDF-----------NNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVNS-----KCKCKPGYNGDSCEED-INECQWPISKHGCIGECRNTFGNYECICP 2709
+D C+ C +G+C+ +C C G++ C+ E CV+ + +F C C T C L++ CS CQ+GGTC+ CQC G+ G +C+ I+ C GN C+++ N ++C C+ F ++D + K E ++ + +C CK G+ G++C++D+DEC L C+ C+N GSY+C C +G+ CAIN + C G CL+GI C C G+ G+ C DI+EC + C++ C S+ C C GF+ Q N + C SC + CLNG C + C CP G+ G C E+ D+C SPCE+ C+ + C C G+ D+ D K L + C GTC N + C C +G+AG C+ +I+EC +Q CQ+ C + IG++ C+C+ G + + C P C + H + N C C G G C+ + ++CK + C++ G ++C C PGF+ + C+ + C + C N C C+ G G C+ +D C Q CQ+ NC + C CN FY G++C L D S+PC+ G V +C+C G G+ CE D ++EC G C + G+YEC+CP
Sbjct: 716 VDECISSPCANNGVCIDQVNGYKCECPRGFYDAHCLSDVDECASNP----CVNEGRCEDGINEFICHCPPGYTGKRCELDIDECSSNPCQHGGTCYDKLNAFSCQCMPGYTGQKCETNIDDCVTNPCGNGG---TCIDK-VNGYKCVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTKGY---EGRDCAINTDDCASFPCQNGGTCLDGIGDYSCLCVDGFDGKHCETDINEC-LSQPCQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSCLNGGSCIDGINGYNCSCLAGYSGANCQYKLNKCDSNPCLNGATCHEQNNEYTCHCPSGFTGKQCSEYVDWCG-QSPCENGATCSQMKHQFSCKCSAGWTGKLCDVQTISCQDAADRKGLSLRQLCNNGTCKDYGNSHVCYCSQGYAGSYCQKEIDECQSQP-CQNGGTCRDLIGAYECQCRQGFQGQNCELNIDDCAP---NPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCKPGACHNNGSCIDRVGGFECVCQPGFVGA----RCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDFCA--QSPCQNGGNCNIRQSGHHCICNNGFY-----GKNCELSGQDCDSNPCRVGNCVVADEGFGYRCECPRGTLGEHCEIDTLDECSPNPCAQG--AACEDLLGDYECLCP 1442
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Match: frac (gene:FBgn0035798 transcript:FBtr0290277) HSP 1 Score: 184.882 bits (468), Expect = 4.471e-47 Identity = 191/641 (29.80%), Postives = 272/641 (42.43%), Query Frame = 1
Query: 964 ICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFE--GDQCQLEINSCS---RGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEE-----------CSK---FGTTEVVSGNCKCKQGWKGK-FCNDDVDECL--FPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG------DCLNGICYCFSGWH----GEDCSLDIDECKYNHG-CEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQ-CFNS----KCICKSGYR----GKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECL-LNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEE--DINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQ 2748
+ G ++ NN + C + C+N F RC C EG+ DQ ++SC+ Q+ C H C + E +++C C G++L D SC+ +E CS + + S +C C G++ + F D+DEC +C C NT G YQC C EG L+ C L N NG G+C C G+ G+ C D+DEC N+G C+ +C N+PGS+ C C +G+ L ++ + G D D+C H C C +N + C C PGY L D L T +E P L DI+EC L C H C N G F C C G+ L+ED R+C + CLD + Q C N C C++G+ G C DI+EC + C C+N G++ C+C G+ L+ + SC +D+DEC L C H C+N G++ C C L + L+ DGRSC C + + +C PGY S ++ DI+ECQ GC C NT G+++C CPPGY + DQKTCQ
Sbjct: 418 VDGPEDLDNNAV----CQQKCENTIGSF--RCTCVEGYHLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSEDQHSCLVQESPCSTEKGVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDECAEDTHLCSHTCQNTPGGYQCQCPEGLNLVEEYTCLAENLCEVNNNGCEQICLTARGGVCACREGFRLSADGKSCE-DVDECLVNNGGCQQVCRNLPGSYGCICAAGYEL-----------LKLDGIRGYCFDIDECS----QRTHGCSDQMLCE----------NLNGSYTCLCPPGYALGLDNHIVTSLNSSFITDSTSSET----PSAHTCL----DIDECSLANGNCSHFCQNEPGGFQCACPLGYALSEDMRTCQ--DIDECLDSNGQCSQLCLNQPGGFACACETGFELTPDGFGC-ADIDECSQDYGNCSDICINLLGTHACACERGYELAKDKLSC------------------------------LDVDECAGLLSGGCSHECINKAGTFECGCPLGYILND-DGRSCSPALVGCPPGTQRSADGC-APIECNPGYTLGSDDKCVDIDECQK--QNGGCSHRCSNTEGSFKCSCPPGYELDSDQKTCQ 981 HSP 2 Score: 144.436 bits (363), Expect = 1.919e-34 Identity = 221/767 (28.81%), Postives = 306/767 (39.90%), Query Frame = 1
Query: 1054 RCQCTEGFEGDQCQ----LEINSCSRGQMGNRTCEHICVN-EGENNFQCKCQSGFQLDNDGKSCIK-EECSKF-------GTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQC--SCREGFTLLSNG-------KCAINCLNNCNKNG----DCLNGI----CYCFSGWH----GEDCSLD----IDECKYNHG-CEHLCVNVP-GSFNCQCHSGFTLQINKKKCI------SKSCNIECLNGGLCDKDK------CKCPPGYIGH--NCEFNDFC-HFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG------TCNENKCKCPKGFA----GLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHIC--EHFCMNTEGSYKCSCMPGFILSANSHSCQSV------------------------CSLCKNGKCDF-------NNKCKCKTGWT----GELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKN-GGKCVN----SKCKCKPGY----NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPI------GFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
+C C EG+ D L+I+ C G C IC N GE ++C CQ G+ LD GKSC+ EC+ G E + G+ +C + + +V E ++ VN S +C GF L ++G +C ++ + + N C N I C C G+H C+LD ++ + N C H C ++P GS+ C C G+ L ++ C+ S +E + G C + C CP GY +C+ D C C H C C C G +L+ + + C G T C C +GF G CE D++ECL N CQ VC N GS+ C C G++L L D + G CF DI+EC + +H C + C N GSY C C PG+ L ++H S+ CSL NG C +C C G+ C DIDECL + +C C+N G ++C+C F L T DG C + D CS N C+N C C+ GY + SC D++EC +S GC EC N G +EC CP GY++ DD ++C S C P G R C PI D VD+DECQ+ R C NT GSF C C Y L D +C + E
Sbjct: 273 KCDCREGYTLDPNDYASCLDIDECLESNGG---CSEICENLPGE--YKCSCQEGYYLDESGKSCVDINECANPELSSNCQGACENLPGSYRCVEPLEENPEITEVVENPIEKTNEVPVNVSESQPAGKTCNSGFQLSADGTDCQDINECEVDGPEDLDNNAVCQQKCENTIGSFRCTCVEGYHLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSEDQHSCLVQESPCSTEKGVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDECAEDTHLCSHTCQNTPGGYQCQCPEGLNLVEEYTCLAENLCEVNNNGCEQICLTARGGVCACREGFRLSADGKSCE-DVDECLVNNGGCQQVCRNLPGSYGCICAAGYEL---------------LKLDGIRGYCF-----------------DIDECSQRTHGCSDQMLCENLNGSYTCLCPPGYALGLDNHIVTSLNSSFITDSTSSETPSAHTCLDIDECSLA-NGNCSHFCQNEPGGFQCACPLGYALSEDMRTCQ-DIDECLDSNGQCSQLCLNQPGGFACACETGFEL-TPDGFGCADI-DECSQDYGNCSDICINLLGTHACACERGYELAKDKLSCL-DVDECAGLLSG-GCSHECINKAGTFECGCPLGYILNDDGRSC--SPALVGCPP-----GTQRSADGC-APIECNPGYTLGSDDKCVDIDECQKQNGGCSHR--CSNTEGSFKCSCPPGYELDSDQKTCQDIDE 985 HSP 3 Score: 66.2402 bits (160), Expect = 1.822e-10 Identity = 108/421 (25.65%), Postives = 165/421 (39.19%), Query Frame = 1
Query: 1906 NKCKCPKGFAGLLCEND------INECLNQTI-CQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICE-------HFCMNTEGSYKC--SCMPGFILSANSHSCQSVCSLCKNGKCDFNN---------------KCKCKTGWTGELCD----------VDIDECLLNQHKCQHNCVN-SNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCK----NGGKCVNSK------CKCKPGYNGDSCE-EDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVL 3009
NKC C +G+ L ND I+ECL C +C N G + C C+ G+ L E +SC+ N+ C + + N + C++ RC E + E + + + E +N S +C GF LSA+ CQ + +G D +N +C C G+ L + D++ LN+ +C H C + GSY C C + LS D SCL + CS+ + G C+ S+ C C GY ++ +DI+EC H C C+NT G Y+C CP G L L ++ TC ++ C + +G C++ IC G C C + L DG SC + E ++
Sbjct: 272 NKCDCREGYT--LDPNDYASCLDIDECLESNGGCSEICENLPGEYKCSCQEGYYLDESGKSCVDINE--CANPELSS----NCQGACENLPGSYRCVEPLEENPEITEVVENPIEKTNEVPVNVSESQPAGKTCNSGFQLSADGTDCQDINECEVDGPEDLDNNAVCQQKCENTIGSFRCTCVEGY--HLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSE-DQHSCLVQESPCSTEKGVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDECAE--DTHLCSHTCQNTPGGYQCQCPEG-LNLVEEYTC---------------------LAENLCEVNNNG---------CEQ---------ICLTARGGV-CACREGFRLSADGKSCEDVDECLV 638
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Match: frac (gene:FBgn0035798 transcript:FBtr0301222) HSP 1 Score: 184.882 bits (468), Expect = 4.471e-47 Identity = 191/641 (29.80%), Postives = 272/641 (42.43%), Query Frame = 1
Query: 964 ICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFE--GDQCQLEINSCS---RGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEE-----------CSK---FGTTEVVSGNCKCKQGWKGK-FCNDDVDECL--FPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG------DCLNGICYCFSGWH----GEDCSLDIDECKYNHG-CEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQ-CFNS----KCICKSGYR----GKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECL-LNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEE--DINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQ 2748
+ G ++ NN + C + C+N F RC C EG+ DQ ++SC+ Q+ C H C + E +++C C G++L D SC+ +E CS + + S +C C G++ + F D+DEC +C C NT G YQC C EG L+ C L N NG G+C C G+ G+ C D+DEC N+G C+ +C N+PGS+ C C +G+ L ++ + G D D+C H C C +N + C C PGY L D L T +E P L DI+EC L C H C N G F C C G+ L+ED R+C + CLD + Q C N C C++G+ G C DI+EC + C C+N G++ C+C G+ L+ + SC +D+DEC L C H C+N G++ C C L + L+ DGRSC C + + +C PGY S ++ DI+ECQ GC C NT G+++C CPPGY + DQKTCQ
Sbjct: 418 VDGPEDLDNNAV----CQQKCENTIGSF--RCTCVEGYHLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSEDQHSCLVQESPCSTEKGVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDECAEDTHLCSHTCQNTPGGYQCQCPEGLNLVEEYTCLAENLCEVNNNGCEQICLTARGGVCACREGFRLSADGKSCE-DVDECLVNNGGCQQVCRNLPGSYGCICAAGYEL-----------LKLDGIRGYCFDIDECS----QRTHGCSDQMLCE----------NLNGSYTCLCPPGYALGLDNHIVTSLNSSFITDSTSSET----PSAHTCL----DIDECSLANGNCSHFCQNEPGGFQCACPLGYALSEDMRTCQ--DIDECLDSNGQCSQLCLNQPGGFACACETGFELTPDGFGC-ADIDECSQDYGNCSDICINLLGTHACACERGYELAKDKLSC------------------------------LDVDECAGLLSGGCSHECINKAGTFECGCPLGYILND-DGRSCSPALVGCPPGTQRSADGC-APIECNPGYTLGSDDKCVDIDECQK--QNGGCSHRCSNTEGSFKCSCPPGYELDSDQKTCQ 981 HSP 2 Score: 144.436 bits (363), Expect = 1.919e-34 Identity = 221/767 (28.81%), Postives = 306/767 (39.90%), Query Frame = 1
Query: 1054 RCQCTEGFEGDQCQ----LEINSCSRGQMGNRTCEHICVN-EGENNFQCKCQSGFQLDNDGKSCIK-EECSKF-------GTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQC--SCREGFTLLSNG-------KCAINCLNNCNKNG----DCLNGI----CYCFSGWH----GEDCSLD----IDECKYNHG-CEHLCVNVP-GSFNCQCHSGFTLQINKKKCI------SKSCNIECLNGGLCDKDK------CKCPPGYIGH--NCEFNDFC-HFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG------TCNENKCKCPKGFA----GLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHIC--EHFCMNTEGSYKCSCMPGFILSANSHSCQSV------------------------CSLCKNGKCDF-------NNKCKCKTGWT----GELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKN-GGKCVN----SKCKCKPGY----NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPI------GFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
+C C EG+ D L+I+ C G C IC N GE ++C CQ G+ LD GKSC+ EC+ G E + G+ +C + + +V E ++ VN S +C GF L ++G +C ++ + + N C N I C C G+H C+LD ++ + N C H C ++P GS+ C C G+ L ++ C+ S +E + G C + C CP GY +C+ D C C H C C C G +L+ + + C G T C C +GF G CE D++ECL N CQ VC N GS+ C C G++L L D + G CF DI+EC + +H C + C N GSY C C PG+ L ++H S+ CSL NG C +C C G+ C DIDECL + +C C+N G ++C+C F L T DG C + D CS N C+N C C+ GY + SC D++EC +S GC EC N G +EC CP GY++ DD ++C S C P G R C PI D VD+DECQ+ R C NT GSF C C Y L D +C + E
Sbjct: 273 KCDCREGYTLDPNDYASCLDIDECLESNGG---CSEICENLPGE--YKCSCQEGYYLDESGKSCVDINECANPELSSNCQGACENLPGSYRCVEPLEENPEITEVVENPIEKTNEVPVNVSESQPAGKTCNSGFQLSADGTDCQDINECEVDGPEDLDNNAVCQQKCENTIGSFRCTCVEGYHLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSEDQHSCLVQESPCSTEKGVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDECAEDTHLCSHTCQNTPGGYQCQCPEGLNLVEEYTCLAENLCEVNNNGCEQICLTARGGVCACREGFRLSADGKSCE-DVDECLVNNGGCQQVCRNLPGSYGCICAAGYEL---------------LKLDGIRGYCF-----------------DIDECSQRTHGCSDQMLCENLNGSYTCLCPPGYALGLDNHIVTSLNSSFITDSTSSETPSAHTCLDIDECSLA-NGNCSHFCQNEPGGFQCACPLGYALSEDMRTCQ-DIDECLDSNGQCSQLCLNQPGGFACACETGFEL-TPDGFGCADI-DECSQDYGNCSDICINLLGTHACACERGYELAKDKLSCL-DVDECAGLLSG-GCSHECINKAGTFECGCPLGYILNDDGRSC--SPALVGCPP-----GTQRSADGC-APIECNPGYTLGSDDKCVDIDECQKQNGGCSHR--CSNTEGSFKCSCPPGYELDSDQKTCQDIDE 985 HSP 3 Score: 66.2402 bits (160), Expect = 1.822e-10 Identity = 108/421 (25.65%), Postives = 165/421 (39.19%), Query Frame = 1
Query: 1906 NKCKCPKGFAGLLCEND------INECLNQTI-CQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICE-------HFCMNTEGSYKC--SCMPGFILSANSHSCQSVCSLCKNGKCDFNN---------------KCKCKTGWTGELCD----------VDIDECLLNQHKCQHNCVN-SNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCK----NGGKCVNSK------CKCKPGYNGDSCE-EDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVL 3009
NKC C +G+ L ND I+ECL C +C N G + C C+ G+ L E +SC+ N+ C + + N + C++ RC E + E + + + E +N S +C GF LSA+ CQ + +G D +N +C C G+ L + D++ LN+ +C H C + GSY C C + LS D SCL + CS+ + G C+ S+ C C GY ++ +DI+EC H C C+NT G Y+C CP G L L ++ TC ++ C + +G C++ IC G C C + L DG SC + E ++
Sbjct: 272 NKCDCREGYT--LDPNDYASCLDIDECLESNGGCSEICENLPGEYKCSCQEGYYLDESGKSCVDINE--CANPELSS----NCQGACENLPGSYRCVEPLEENPEITEVVENPIEKTNEVPVNVSESQPAGKTCNSGFQLSADGTDCQDINECEVDGPEDLDNNAVCQQKCENTIGSFRCTCVEGY--HLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSE-DQHSCLVQESPCSTEKGVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDECAE--DTHLCSHTCQNTPGGYQCQCPEG-LNLVEEYTC---------------------LAENLCEVNNNG---------CEQ---------ICLTARGGV-CACREGFRLSADGKSCEDVDECLV 638
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Match: frac (gene:FBgn0035798 transcript:FBtr0301221) HSP 1 Score: 184.882 bits (468), Expect = 4.471e-47 Identity = 191/641 (29.80%), Postives = 272/641 (42.43%), Query Frame = 1
Query: 964 ICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFE--GDQCQLEINSCS---RGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEE-----------CSK---FGTTEVVSGNCKCKQGWKGK-FCNDDVDECL--FPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG------DCLNGICYCFSGWH----GEDCSLDIDECKYNHG-CEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQ-CFNS----KCICKSGYR----GKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECL-LNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEE--DINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQ 2748
+ G ++ NN + C + C+N F RC C EG+ DQ ++SC+ Q+ C H C + E +++C C G++L D SC+ +E CS + + S +C C G++ + F D+DEC +C C NT G YQC C EG L+ C L N NG G+C C G+ G+ C D+DEC N+G C+ +C N+PGS+ C C +G+ L ++ + G D D+C H C C +N + C C PGY L D L T +E P L DI+EC L C H C N G F C C G+ L+ED R+C + CLD + Q C N C C++G+ G C DI+EC + C C+N G++ C+C G+ L+ + SC +D+DEC L C H C+N G++ C C L + L+ DGRSC C + + +C PGY S ++ DI+ECQ GC C NT G+++C CPPGY + DQKTCQ
Sbjct: 418 VDGPEDLDNNAV----CQQKCENTIGSF--RCTCVEGYHLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSEDQHSCLVQESPCSTEKGVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDECAEDTHLCSHTCQNTPGGYQCQCPEGLNLVEEYTCLAENLCEVNNNGCEQICLTARGGVCACREGFRLSADGKSCE-DVDECLVNNGGCQQVCRNLPGSYGCICAAGYEL-----------LKLDGIRGYCFDIDECS----QRTHGCSDQMLCE----------NLNGSYTCLCPPGYALGLDNHIVTSLNSSFITDSTSSET----PSAHTCL----DIDECSLANGNCSHFCQNEPGGFQCACPLGYALSEDMRTCQ--DIDECLDSNGQCSQLCLNQPGGFACACETGFELTPDGFGC-ADIDECSQDYGNCSDICINLLGTHACACERGYELAKDKLSC------------------------------LDVDECAGLLSGGCSHECINKAGTFECGCPLGYILND-DGRSCSPALVGCPPGTQRSADGC-APIECNPGYTLGSDDKCVDIDECQK--QNGGCSHRCSNTEGSFKCSCPPGYELDSDQKTCQ 981 HSP 2 Score: 144.436 bits (363), Expect = 1.919e-34 Identity = 221/767 (28.81%), Postives = 306/767 (39.90%), Query Frame = 1
Query: 1054 RCQCTEGFEGDQCQ----LEINSCSRGQMGNRTCEHICVN-EGENNFQCKCQSGFQLDNDGKSCIK-EECSKF-------GTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQC--SCREGFTLLSNG-------KCAINCLNNCNKNG----DCLNGI----CYCFSGWH----GEDCSLD----IDECKYNHG-CEHLCVNVP-GSFNCQCHSGFTLQINKKKCI------SKSCNIECLNGGLCDKDK------CKCPPGYIGH--NCEFNDFC-HFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG------TCNENKCKCPKGFA----GLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHIC--EHFCMNTEGSYKCSCMPGFILSANSHSCQSV------------------------CSLCKNGKCDF-------NNKCKCKTGWT----GELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKN-GGKCVN----SKCKCKPGY----NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPI------GFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
+C C EG+ D L+I+ C G C IC N GE ++C CQ G+ LD GKSC+ EC+ G E + G+ +C + + +V E ++ VN S +C GF L ++G +C ++ + + N C N I C C G+H C+LD ++ + N C H C ++P GS+ C C G+ L ++ C+ S +E + G C + C CP GY +C+ D C C H C C C G +L+ + + C G T C C +GF G CE D++ECL N CQ VC N GS+ C C G++L L D + G CF DI+EC + +H C + C N GSY C C PG+ L ++H S+ CSL NG C +C C G+ C DIDECL + +C C+N G ++C+C F L T DG C + D CS N C+N C C+ GY + SC D++EC +S GC EC N G +EC CP GY++ DD ++C S C P G R C PI D VD+DECQ+ R C NT GSF C C Y L D +C + E
Sbjct: 273 KCDCREGYTLDPNDYASCLDIDECLESNGG---CSEICENLPGE--YKCSCQEGYYLDESGKSCVDINECANPELSSNCQGACENLPGSYRCVEPLEENPEITEVVENPIEKTNEVPVNVSESQPAGKTCNSGFQLSADGTDCQDINECEVDGPEDLDNNAVCQQKCENTIGSFRCTCVEGYHLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSEDQHSCLVQESPCSTEKGVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDECAEDTHLCSHTCQNTPGGYQCQCPEGLNLVEEYTCLAENLCEVNNNGCEQICLTARGGVCACREGFRLSADGKSCE-DVDECLVNNGGCQQVCRNLPGSYGCICAAGYEL---------------LKLDGIRGYCF-----------------DIDECSQRTHGCSDQMLCENLNGSYTCLCPPGYALGLDNHIVTSLNSSFITDSTSSETPSAHTCLDIDECSLA-NGNCSHFCQNEPGGFQCACPLGYALSEDMRTCQ-DIDECLDSNGQCSQLCLNQPGGFACACETGFEL-TPDGFGCADI-DECSQDYGNCSDICINLLGTHACACERGYELAKDKLSCL-DVDECAGLLSG-GCSHECINKAGTFECGCPLGYILNDDGRSC--SPALVGCPP-----GTQRSADGC-APIECNPGYTLGSDDKCVDIDECQKQNGGCSHR--CSNTEGSFKCSCPPGYELDSDQKTCQDIDE 985 HSP 3 Score: 66.2402 bits (160), Expect = 1.822e-10 Identity = 108/421 (25.65%), Postives = 165/421 (39.19%), Query Frame = 1
Query: 1906 NKCKCPKGFAGLLCEND------INECLNQTI-CQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICE-------HFCMNTEGSYKC--SCMPGFILSANSHSCQSVCSLCKNGKCDFNN---------------KCKCKTGWTGELCD----------VDIDECLLNQHKCQHNCVN-SNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCK----NGGKCVNSK------CKCKPGYNGDSCE-EDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVL 3009
NKC C +G+ L ND I+ECL C +C N G + C C+ G+ L E +SC+ N+ C + + N + C++ RC E + E + + + E +N S +C GF LSA+ CQ + +G D +N +C C G+ L + D++ LN+ +C H C + GSY C C + LS D SCL + CS+ + G C+ S+ C C GY ++ +DI+EC H C C+NT G Y+C CP G L L ++ TC ++ C + +G C++ IC G C C + L DG SC + E ++
Sbjct: 272 NKCDCREGYT--LDPNDYASCLDIDECLESNGGCSEICENLPGEYKCSCQEGYYLDESGKSCVDINE--CANPELSS----NCQGACENLPGSYRCVEPLEENPEITEVVENPIEKTNEVPVNVSESQPAGKTCNSGFQLSADGTDCQDINECEVDGPEDLDNNAVCQQKCENTIGSFRCTCVEGY--HLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSE-DQHSCLVQESPCSTEKGVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDECAE--DTHLCSHTCQNTPGGYQCQCPEG-LNLVEEYTC---------------------LAENLCEVNNNG---------CEQ---------ICLTARGGV-CACREGFRLSADGKSCEDVDECLV 638
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Match: notch1b (notch receptor 1b [Source:ZFIN;Acc:ZDB-GENE-990415-183]) HSP 1 Score: 228.409 bits (581), Expect = 1.394e-60 Identity = 245/793 (30.90%), Postives = 347/793 (43.76%), Query Frame = 1
Query: 802 CGEHGICVKSR----CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNNCNKNG-DCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFN-DFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCV------RGTC----NENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C G C+ ++ C C GW G+ C E C G + R F C C T C L+ S CQ G C + C C G+ G C +++ CS +G CEH C+N + +FQCKC G+ + + D C+ C T ++ +C C G++G FC + DEC C C++ I +YQC C GF S +C + C + KNG C++G C C G+ G+ C D+DEC N C + SF C C +GF +IN +C+S+ C NGG C + C CP G G NCE N D C +PC+ C + C+C PGY K C + +C GTC N C C +G+ C++ +NECL+ C + + + C C +G + C+ N TC KD G C C++G+ G C +INEC + + C++ YKC+C+ L +C+++ + C + C CK C GW G+ C+VDI+EC+ N + C NS GSY CSC + GR+C D C +PC NGG C ++ C C PG+ G CEEDINEC+ K+G C + +Y C CPPG+ + C+ +T D C NGG C D C CP GF G C D++EC PC G C ++YG++ C C Y
Sbjct: 257 CQNGGTCLNTQGGYNCVCVNGWTGDDCS----ENIDDCADAACHTGATCHDRVASFLCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPLGYVGPACDQDVDECS---LGANPCEHAGKCINT-KGSFQCKCLQGYVGARCELDINECLSTPCQNDATCLDQIGGFHCICMPGYEGVFCQINTDECASMPCLNNGKCIDKINNYQCECPTGF---SGSQCQFDIDECASTPCKNGAKCMDGPNMYTCQCTEGYTGQHCETDVDECLSNPCHYGTCKDGLASFTCVCRAGFMGRLCEININECLSQPCQ----NGGTCQDRENAYLCVCPKGTAGANCEINLDDCQS-NPCDFGRCIDKINGYECACEPGYT----GKMCN-INIDECAINPCHNGGTCVDGVNGFTCLCREGYHDTTCQSQLNECLSNPCIHGHCEDKVNGYNCICDSGWSGVNCDINNNECESNPCM--NGGTC--KDMTSGYV----CTCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL----LPYTGENCETLLAPCGSKPCKNGGVCKESEDYESFSCVCPAGWQGQTCEVDINECVKNPCRNDAICQNSIGSYKCSCKAGYT-----GRNCETDIDDCKPNPCSNGGFCKDAVNAFACTCLPGFRGGRCEEDINECESNPCKNG--ANCTDCVNSYTCTCPPGFSGIH----CENNTPDCT-ESSCFNGGTCVDGINSFTCLCPKGFTGNYCQHDINECDSR-PCMN-GGTCQDSYGTYKCTCPQGY 1002 HSP 2 Score: 184.111 bits (466), Expect = 1.379e-46 Identity = 215/721 (29.82%), Postives = 308/721 (42.72%), Query Frame = 1
Query: 1024 CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT-TEVVSGN-CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-------DCLNGICYCFSGWHGEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQ--------SVCSLCKN-GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQW---PISKHG-CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGV-CRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLR--GICYNTYGSFYCQCSSNYVLM---YDGTSCMTMK 2997
C NGGTC G C C EG+ CQ ++N C + C H + N + C C SG+ D + C C GT ++ SG C C+ G+ G C +++EC C Q C++ + Y+C+C +T + C + KNG D + C C +GW G+ C +DI+EC N + +C N GS+ C C +G+T + N + I C NGG C C C PG+ G CE + +PC++ NCT ++ C+C PG+ + PD CV G N C CPKGF G C++DINEC D R C+ N TC D + KC C GY G C E +N CK C + Y C C G+ S SC+ V LC+N G+C D N C C+ G+TG C+ +DEC+ N + C + G YSC C +P Y G +C ++ + C S PC+NGG C++ KC C G G CE +I++C PI+ C G C + G Y CICPPGY+ + C+ + + NP + + ++ RC C G+ G C D C + PC + NT F C+C + YD +C +++
Sbjct: 638 CHNGGTCVDGVNGFTCLCREGYHDTTCQSQLNECL-----SNPCIHGHCEDKVNGYNCICDSGWSGVNCDINNNECESNPCMNGGTCKDMTSGYVCTCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGENCETLLAPCGSKPCKNGGVCKESEDYESFSCVCPAGWQGQTCEVDINECVKNPCRNDAICQNSIGSYKCSCKAGYTGR-NCETDIDDCKPNPCSNGGFCKDAVNAFACTCLPGFRGGRCEEDINECESNPCKNGANCTDCVNSYTCTCPPGFSGIHCENNTPDCTESSCFNGGTCVDGI-NSFTCLCPKGFTGNYCQHDINEC-----------------------------DSRPCM--NGGTCQDSYGTY------KCTCPQGYHGLNCQELVNWCKPSPCKNGGICRQSGTRYSCQCQTGWTGLYCDVPSVSCEVAAKQQGVDVVRLCRNSGQCLDAGNTHYCHCQAGYTGSYCEEQVDECIPNPCQNGATCTDYLGGYSCEC-VPGY----HGVNCSDEINECLSQPCQNGGTCIDLINTYKCSCPRGTQGVHCEINIDDCTPFTDPITHEPKCFNQGRCVDRVGGYHCICPPGYV----GERCEGDVNECLSNPCGTHSCIQLKNNYRCECRTGYTGQHCDKVFDGC-KGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAHACGSLQ 1304 HSP 3 Score: 181.03 bits (458), Expect = 1.198e-45 Identity = 231/808 (28.59%), Postives = 346/808 (42.82%), Query Frame = 1
Query: 952 DFSCICGIKETQNNCLELRTC-SKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSR-----------------------GQMGNRTCEHI--------------CVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFT-------------------------------LLSNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSK-----CICKSGYRGKRCDEDINECKKYSHICEH-FCMNTEGSYKCSCMPGFILSA-NSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
++ C C + C + C S C NGG C C CT F G C+ ++N C++ + + CE + CV +GE +++C C GF N + C C GT V + NC+CK W G+FC +DV+EC L P CQ C+NT G Y C C G+T +G+ + C N C K +C +NG IC C G+ G C D+DEC + CEH C+N GSF C+C G+ +++ +C+S C + CL+ GG C C PGY G C+ N D C + PC +N I+ +N C C G+ D C C KC+ G N C+C +G+ G CE D++ECL+ C + + SF C C+ G R C N CL + C +G + C+C G G C+ ++++C+ S+ C+ C++ Y+C+C PG+ N + + + C NG + C C+ G+ C ++ECL N C H +C + Y+C C+ S G +C N+ C S+PC NGG C + C C+ G++G +C+ +INEC + + C+ G C + Y+C C L+ + C+ P C NGGVC++ C CP G+ G C VD++EC + PC + IC N+ GS+ C C + Y
Sbjct: 75 NYRCKCPPGWSGKTCQQADPCASNPCANGGQCSPFDSDFLCHCTPYFSGQTCKQDVNECAQIPSPCKNGGVCENGVGTYHCNCPAEYTGKHCESLYQPCNPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNTYNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVNGWTGDDCSENIDDCADAACHTGATCHDRVASFLCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPLGYVGPACDQDVDECSLGANPCEHAGKCINTKGSFQCKCLQGYVGARCELDINECLSTPCQNDATCLDQIGGF----HCICMPGYEGVFCQINTDECASM-PCLNNGKCIDKINNYQCECPTGFSGSQCQFDIDECASTPCKNGAKCMDGP-NMYTCQCTEGYTGQHCETDVDECLSNPCHYGTCKDGLASFTCVCRAGFM----GRLC-EININECLSQPCQNGGTCQDRENAYLCVCPKGTAGANCEINLDDCQ--SNPCDFGRCIDKINGYECACEPGYTGKMCNINIDECAINPCHNGGTCVDGVNGFTCLCREGYHDTTCQSQLNECLSN--PCIHGHCEDKVNGYNCICD-----SGWSGVNCDINNNECESNPCMNGGTCKDMTSGYVCTCRAGFSGPNCQTNINEC----ASNPCLNQGTCIDDVAGYKCNC----LLPYTGENCETLLAPCGSKP-CKNGGVCKESEDYESFSCVCPAGWQGQTCEVDINECVK-NPC-RNDAICQNSIGSYKCSCKAGYT 851 HSP 4 Score: 155.992 bits (393), Expect = 7.687e-38 Identity = 208/740 (28.11%), Postives = 304/740 (41.08%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQSGFQLDN---DGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINC-LNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH-------NCTTINDNMVCSCLPGYDLMPDKKT---CKKLECPK--CVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHV-----------CTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQSVCSLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR-----CYCPIGFHGIDCGV 2859
C+HG DK ++CIC + NC + C S C NGGTC C C GF G CQ IN C+ + C+N+G ++C C + +N C + C G + + S +C C GW+G+ C D++EC+ C+ IC N+IGSY+CSC+ G+T + +C N C+ G C + + C C G+ G C DI+EC+ N +G C + S+ C C GF+ + N C SC NGG C + C CP G+ G+ C+ H I+ C+ C C+C GY + ++ CK C R + C+C G+ GL C+ C Q V C + + +C C+ G+ + E CIP N TC D C C GY G C ++INEC S C++ C++ +YKCSC G N C + FN C C G+ GE C+ D++ECL N H+C+ +Y C C + G+ C + D C PC+NGG C + CKC PG+ G +CE D + C K+G G C + + +C+C P + + CQ + C NGG C ++ C CP F+G+ C +
Sbjct: 676 CIHGHCEDKVN-GYNCICDSGWSGVNCDINNNECESNPCMNGGTCKDMTSGYVCTCRAGFSGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCLLPYTGENCETLLAPCGSKPCKNGGVCKESEDYESFSCVCPAGWQGQTCEVDINECVKNPCRNDAICQNSIGSYKCSCKAGYTGRNCETDIDDCKPNPCSNGGFCKDAVNAFACTCLPGFRGGRCEEDINECESNPCKNGAN--CTDCVNSYTCTCPPGFSGIHCENNTPDCTESSC----FNGGTCVDGINSFTCLCPKGFTGNYCQ-----HDINECDSRPCMNGGTCQDSYGTYKCTCPQGYHGLNCQELVNWCKPSPCKNGGICRQSGTRYSCQCQTGWTGLYCDVPSVSCEVAAKQQGVDVVRLCRNSGQCLDAGNTHYCHCQAGYTGSYCEEQVDECIPNPCQNGATCTDY------LGGYSCECVPGYHGVNCSDEINEC--LSQPCQNGGTCIDLINTYKCSCPRGTQGVHCEINIDDCTPFTDPITHEPKCFNQGRCVDRVGGYHCICPPGYVGERCEGDVNECLSNPCG-THSCIQLKNNYRCECRTGYT-----GQHCDKVFDGCKGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAHACGSLQCKNG--GTCVSGHKSPKCLCTPAFTGPE----CQDPSGGHCTTNPCYNGGTCEYITEEPYYHCICPTNFNGLFCHI 1374 HSP 5 Score: 146.362 bits (368), Expect = 7.349e-35 Identity = 162/502 (32.27%), Postives = 227/502 (45.22%), Query Frame = 1
Query: 1594 FNCQCHSGFTLQINKKKCISKSCNI----ECLNGGLCDKD-----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLP---GYDLMPDKKTCKKLECPKCVRGTCNEN-----KCKCPKGFAGLLCENDINECLNQTICQHVCT---NTIGSFFCRCK---NGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFIL---SANSHSCQSVC----SLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNS--NGSYSCSCNLPFYLSTVDGRSCLEKNDSCS---SPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
F C C G+T ++ C++ + N+ C NGG C+ +CKCPPG+ G C+ D C +PC + C+ + + +C C P G D C ++ P C G EN C CP + G CE+ C N + C H T S+ C C +G E+ C P+ + CV G C CK + G+ C ED+NEC + C++ C+NT+G Y C C+ G+ S N C + C + F C+C G TG LC +D D C+ N + NC + NG C+C L + G +C + D CS +PC++ GKC+N+K CKC GY G CE DINEC ++ C + G + CIC PGY + CQI+T + P CLN G C D +C CP GF G C D+DEC PC K C + + CQC+ Y
Sbjct: 36 FVCNCSLGYTDRL----CLTPTNNVCLGAPCRNGGTCELTSIHNYRCKCPPGWSGKTCQQADPC-ASNPCANGGQCSPFDSDFLCHCTPYFSGQTCKQDVNECAQIPSP-CKNGGVCENGVGTYHCNCPAEYTGKHCESLYQPC-NPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDC--PDHRCLNGGTCVDG-VNTYNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVNGWTGDDCSENIDDCADAACHTGATCHDRVASF--LCECPHGRTGLLCHLD-DACISNPCQKGSNCDTNPVNGKAICTCPLGYV-----GPACDQDVDECSLGANPCEHAGKCINTKGSFQCKCLQGYVGARCELDINECLSTPCQNDAT--CLDQIGGFHCICMPGY----EGVFCQINTDECASMP-CLNNGKCIDKINNYQCECPTGFSGSQCQFDIDECAS-TPC-KNGAKCMDGPNMYTCQCTEGYT 510 HSP 6 Score: 105.531 bits (262), Expect = 2.132e-22 Identity = 130/449 (28.95%), Postives = 195/449 (43.43%), Query Frame = 1
Query: 1723 YIGHNCEFNDFCHFISPCEHN-----CTTIND-NMVCSCLPGYD----LMPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVC--SLCKNG-----KCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS---SPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVL----DDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYA-PCDKLRGICYNTYGSFYCQCSSNYV 2961
Y G C+F + C F SPC + T+ N + VC+C GY L P C C C + + +CKCP G++G C+ + C + C NG + C P D D + C C + G+ C +D+NEC + C++ C N G+Y C+C P + S C S C +G K + + +C C G++G+ C+ +ID+C H+C + CV+ +Y+C C + G+ C E + C + C+NGG C+N++ C C G+ GD C E+I++C G C + ++ C CP G L DD K + C+ + +NG + C CP+G+ G C DVDEC A PC+ G C NT GSF C+C YV
Sbjct: 3 YAGPACQFRNPC-FQSPCRNGGVCRLITSANKVDFVCNCSLGYTDRLCLTPTNNVCLGAPCRNGGTCELTSIHNYRCKCPPGWSGKTCQQ-ADPCASNP----------------CANGGQ-------CSP------FDSDFL--------CHCTPYFSGQTCKQDVNECAQIPSPCKNGGVCENGVGTYHCNC-PAEYTGKHCESLYQPCNPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCP--DHRCLNGGTCVDGVNTYNCQCKPEWT-----GQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVNGWTGDDCSENIDDCADAACHTGAT--CHDRVASFLCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNG-----KAICTCPLGYVGPACDQDVDECSLGANPCEHA-GKCINTKGSFQCKCLQGYV 396 HSP 7 Score: 103.99 bits (258), Expect = 7.477e-22 Identity = 145/580 (25.00%), Postives = 215/580 (37.07%), Query Frame = 1
Query: 802 CGEHGICVKSR------CYCETGWFGERCVILEPELCKQ--RKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLS---------------NGKC----------------------------------AINCLNNCNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFN--DFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGH------KLAEDKRSCIPPNKKTC-LDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI 2274
C G+C +S C C GW G+ C + E K R C + + C C T NC ++ C C NGG C C C GF G +C+ +IN C N CVN ++ C C GF +N+ C + C GT + S C C +G+ G +C D++EC C C ++ G+Y+C+C +G+ L+ G C ++ + C +G CL+ C+C +G+ G C +DEC N C++ C + G ++C+C G+ +N I++ + C NGG C + KC CP G G +CE N D F P H N + GY C CP G+ G CE D+NECL+ H C ++ C C+ G+ K+ + + N TC + + HG C C G+ G C+ D + C C++ S KC C P F
Sbjct: 789 CKNGGVCKESEDYESFSCVCPAGWQGQTCEVDINECVKNPCRNDAICQNSIG------SYKCSCKAGYTGRNCETDIDDCKPNPCSNGGFCKDAVNAFACTCLPGFRGGRCEEDINECESNPCKNGANCTDCVN----SYTCTCPPGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPKGFTGNYCQHDINECDSRPCMNGGTCQDSYGTYKCTCPQGYHGLNCQELVNWCKPSPCKNGGICRQSGTRYSCQCQTGWTGLYCDVPSVSCEVAAKQQGVDVVRLCRNSGQCLDAGNTHYCHCQAGYTGSYCEEQVDECIPNP-CQNGATCTDYLGGYSCECVPGYH-GVNCSDEINECLSQPCQNGGTCIDLINTYKCSCPRGTQGVHCEINIDDCTPFTDPITHEPKCFNQGRCVDRVGGY-------------------------HCICPPGYVGERCEGDVNECLSNPCGTHSCIQLKNNYRCECRTGYTGQHCDKVFDGCKGKPCRNGGTCAVASNTPHG----FICKCPPGFTGSTCEYDAHACGSLQCKNGGTCVSGHKSPKCLCTPAFT 1327
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Match: notch3 (notch receptor 3 [Source:ZFIN;Acc:ZDB-GENE-000329-5]) HSP 1 Score: 219.935 bits (559), Expect = 6.789e-58 Identity = 235/770 (30.52%), Postives = 332/770 (43.12%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTC----FQGR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT----LLSNGKCAINCLNNCNKNGDCLNGI-CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL-----QINKKKCISKSCNIECLNGG----LCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-TCNENK----CKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE---DKRSCIPP---NKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCD-----------FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKC---VNS-KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C C GW G+ C E C +G + R F C C + +T C L+ S C G C GR C C GF G C +++ CS +G CEH CVN E +FQC+C G+ + + D C+ C T + C C G++GK+C D+DEC C IC + + + C+C+ GFT + +CA N K D NG C C G+ G C +ID CK + CV+ S+ C C G+T Q+N+ C S C NGG L +K C+C G G NCE N +PC++ C + C C PG+ K + + C G TC +++ C+CP+GF C + ++EC + C + + C C+ G D+ C+P N TC D Q C C+ G+RG C +INEC + + C++ S+ C C P + + +C + + C C +C C+ GW G LC+ DI+EC N K + C N+ G Y CSC + G +C + ND +PC NGG C VNS +C C PG+ G C ++NECQ K+G G C + +Y C C PG+ L C+ + D C NGG C D +C C GF G C +V+EC PC GIC + S+ C C Y
Sbjct: 276 CVCVNGWTGDDCS----ENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECS---IGANPCEHFGKCVNT-EGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYQGKYCEVDIDECESNPCVNDGICRDMVNGFTCTCQPGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNCKPDPCHHGTCVDGIASYTCNCEPGYTGYRCENQLNE--CHSNPCQ----NGGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYECVCKPGFTGPQCKDEIDECQSNPCRNGGTCVDDENGFHCQCPEGFHDPYCYSQVDECASNPCLHGTCRDDPNGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCFD------QLNGFTCKCRQGFRGNLCQVNINECASSPCLNQGTCVDGVASFTCLCEPPY----SGPTCAELLTPCSPNPCANHASCVHTPDYLGYQCNCQPGWQGHLCNNDINECTSNPCKNRGTCTNTLGGYVCSCRAGYT-----GPNCETDINDCSPNPCLNGGSCTDGVNSFRCSCLPGFTGARCATELNECQSVPCKNG--GTCTDYVNSYTCTCKPGFTGL----LCETNVPDCT-ESSCFNGGTCTDGINGFKCTCRTGFTGDYCQYEVNECDS-QPCLN-GGICQDAMESYRCSCPKGYT 1007 HSP 2 Score: 206.068 bits (523), Expect = 1.898e-53 Identity = 256/928 (27.59%), Postives = 364/928 (39.22%), Query Frame = 1
Query: 802 CGEHGICVKSRCYCETGWFGERCVILEP---------ELCKQR---------------------------KLLFCVHGCSFDKRKLDFSCICGIKETQNNCL-ELRTCSKG--CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDECLFP--VCQQ--ICVNTIGSYQCSCREGFT-------------------------------LLSNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN-------CTTINDNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGH-------KLAE-------DKRSCI-------------------PPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKK-----------------------------YSHI-------CEH-FCMNTEGSYKCSCMPGFIL---SANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS------KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
C G+C+ SRC C G+ G C L+P CK + C +G ++C C NC ++ C K C NGG C RC+C G+ G C++ C+ Q N C G++ ++C C GF+ N + C +C G V + NC+C W G++C +DV+ECL C C NTIG + C C G+T GK + C N CN+ C LNG IC C +G+ G C+ D+DEC + CEH CVN GSF CQC G+T +I+ +C+S C + + C C PGY G CE + I CE N C + + C+C PG+ D C C KC+ N +C+C +GF G LCE++I+ C C + I S+ C C+ G+ +L E + C+ N C C +G C + +C+CK G+ G +C ++I+EC+ YS + C H C + Y+C C PG++ + + C + S C+N F+ CKC+ G+ G LC V+I+EC + Q CV+ S++C C P+ G +C E CS +PC N CV++ +C C+PG+ G C DINEC K+ G C NT G Y C C GY C+ D NP CLNGG C D RC C GF G C +++ECQ PC K G C + S+ C C + +
Sbjct: 31 CENGGMCIDSRCLCRPGYIGSLCQHLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQDCSLVDACATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECLTGYSGRTCEVPTQPCAPSQCLNGG---TCHQTGDHTYECACLPGFRGHNCEDNVDDCPGHKCMNNGICVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYQGKYCEVD-----IDECESNPCVNDGICRDMVNGFTCTCQPGFTGTMCQIDIDECASTPCQNGAKCIDRP-NGYECRCAEGFEGRLCESNIDNCKPDPCHHGTCVDGIASYTCNCEPGYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYECVCKPGFTGPQCKDEIDECQSNPCRNGGTCVDDENGFHCQCPEGFHDPYCYSQVDECASNPCLHGTCRDDPNGYRCDCEPGWVGKNCDLDRNDC--LPSPCQNAGTCFDQLNGFTCKCRQGFRGNLCQVNINECASSPCLNQGTCVDGVASFTCLCEPPY-----SGPTCAELLTPCSPNPCANHASCVHTPDYLGYQCNCQPGWQGHLCNNDINECTSNPCKN--RGTCTNTLGGYVCSCRAGYT----GPNCETDINDCSPNP-CLNGGSCTDGVNSFRCSCLPGFTGARCATELNECQS-VPC-KNGGTCTDYVNSYTCTCKPGFTGL 933 HSP 3 Score: 203.756 bits (517), Expect = 1.027e-52 Identity = 224/720 (31.11%), Postives = 318/720 (44.17%), Query Frame = 1
Query: 1018 KGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN--DGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDECLFP---VCQQICVNTIGSYQCSCREGFT----LLSNGKCAIN-CLN--NCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECP------------KCVRGTCNENK------------CKCPKGFAGLLCENDINEC-LNQTICQHV--CTNTIGSFFCRCKNGHKLAE---DKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSA---NSHSCQSVCSLCKNG-KC-DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
+ C+NGG C RC C G+ G CQ ++ C R N V + C CQ GF+ + +C C+ T NC C G++GK C +D+DEC P + IC+NT GS++C C G++ + CA + CLN C++ GD C C G+ G +C ++D+C H C + +CV+ ++NCQC +T Q + +C+ + C NGG C C C G+ G +C N I+D C G D+ ECP CV CNE C CP GF G C D++EC + C+H C NT GSF C+C G+ D C+ N TCLD+ CIC GY+GK C+ DI+EC+ + + C + + C+C PGF + + C S + C+NG KC D N +C+C G+ G LC+ +ID C C H CV+ SY+C+C P Y G C + + C S+PC+NGGKCV+ C+C+ G +G +CE + ++C +G C++ YEC+C PG+ C+ + NP C NGG C D C CP GFH C VDEC PC L G C + + C C +V
Sbjct: 29 RPCENGGMCIDSRCLCRPGYIGSLCQ-HLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQDCSLVDACATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECLTGYSGRTCEVPTQPCAPSQCLNGGTCHQTGD-HTYECACLPGFRGHNCEDNVDDCP-GHKCMNNGICVDGVNTYNCQCPPEWTGQYCAEDVNECLMQP--NACHNGGTCFNTIGGHTCVCVNGWTGDDCSEN---------------IDDCATAVCFNGATCH-DRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDR------IGEFTCICMPGYQGKYCEVDIDECESNPCVNDGICRDMVNGFTCTCQPGFTGTMCQIDIDECAS--TPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNC--KPDPCHHGTCVDGIASYTCNCE-PGYT----GYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGI---CKDGINRYECVCKPGFT----GPQCKDEIDECQSNP-CRNGGTCVDDENGFHCQCPEGFHDPYCYSQVDECAS-NPC--LHGTCRDDPNGYRCDCEPGWV 701 HSP 4 Score: 184.111 bits (466), Expect = 1.272e-46 Identity = 228/783 (29.12%), Postives = 313/783 (39.97%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLF-PVCQQICVNTIGSYQCSCREGFTL----LSNGKCAINCLNNCNKNGDCLNGI-CYCFSGWHGEDCSLDIDECK----YNHGCEHLCVNVPGSFNCQC---HSGFTLQINKKKCISKSC--NIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFIS-PCEH--NCTTINDNMVCSCLPGY---DLMPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHK--LAEDKRSCIPPNKKTCLDKDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCK-------NGKC---DFNNKCKCKTGWTGELCDVDIDECLLNQHK--------CQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD------TMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDEC 2874
IDNC PD HG CV C CE G+ G RC + N C S CQNGG C + CQC G G C++ + C+ + C++ +G N ++C C+ GF Q ++ C C GT + +C+C +G+ +C VDEC P C + Y+C C G+ L C + N D LNG C C G+ G C ++I+EC N G CV+ SF C C +SG T C C + C++ +C C PG+ GH C ND S PC++ CT VCSC GY + D C C C G N +C C GF G C ++NEC C++ CT+ + S+ C CK G L E +P DC CFN KC C++G+ G C ++NEC + C + SY+CSC G+ CQ C+ G+C D + C C GW+G CD+ C + + C H +CVN+ ++ C C + G C + D C PC NG C + C C PGY G++CE ++NECQ ++G G C + G+Y C CPPG L + C+I+ D P C N G C D RC CP GF G C D++EC
Sbjct: 522 IDNCKPDPCHHGTCVDGIASYTCNCEPGYTGYRC-----------------------------------ENQLNECH-----SNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINFDDCA-----SNPCDYGICKDGINRYECVCKPGFTGPQCKDEIDECQSNPCRNGGTCVDDENGFHCQCPEGFHDPYCYSQVDECASNPCLHGTCRDDPNGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCFDQLNGFTCKCRQGFRGNLCQVNINECASSPCLNQG---TCVDGVASFTCLCEPPYSGPTCAELLTPCSPNPCANHASCVHTPDYLGYQCNCQPGWQGHLCN-NDINECTSNPCKNRGTCTNTLGGYVCSCRAGYTGPNCETDINDCSPNPCLNGGSCTDGV-NSFRCSCLPGFTGARCATELNEC-QSVPCKNGGTCTDYVNSYTCTCKPGFTGLLCETN---VP---------DCTESSCFNGGTCTDGINGFKCTCRTGFTGDYCQYEVNECDSQPCLNGGICQDAMESYRCSCPKGYT----GPRCQYPVDWCRPSNPCKNGGRCRQKDASFTCDCLGGWSGRYCDIPGVSCEVAARQRGRQTDELCLHGGHCVNTGNTHYCKCPADYT-----GSYCESQFDHCEEKPCLNGATCRSYMGGFTCDCMPGYEGNNCEREVNECQSHPCQNG--GTCIDLVGHYICSCPPGTLGV----LCEINEDDCATPSWPRGMPKCQNNGTCVDRVGGYRCNCPPGFTGERCEGDINEC 1226 HSP 5 Score: 172.555 bits (436), Expect = 5.999e-43 Identity = 236/855 (27.60%), Postives = 333/855 (38.95%), Query Frame = 1
Query: 616 CKPPFCLPRRCDQIDCGQSNCITNSRPCARNNQDCSMEQKRVLFGSEVVCLNKPAIDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN--CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKY----NHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSC----------------------------------NIECLNGGLC----DKDKCKCPPGYIGHNCEFN-DFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQT--ICQHV--CTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS-----KCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMP---GFILSANSHSCQSVCSLCKNGKCDFNN---------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS-------KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDC 2853
CKP F P+ D+ID QSN N C + + + C ++ +D C + HG C RC CE GW G+ C + +N+CL CQN GTCF C+C +GF G+ CQ+ IN C+ N + CV +G +F C C+ SG C C+ T + + C C+ GW+G CN+D++EC C+ C NT+G Y CSCR G+T N + IN N C G C +G+ C C G+ G C+ +++EC+ N G C + S+ C C GFT + N C SC + CLNGG+C + +C CP GY G C++ D+C +PC++ C + + C CL G+ + C P G+ CE + QT +C H C NT + +C+C A+ S C +K C++G S C C GY G C+ ++NEC+ SH C++ C++ G Y CSC P G + N C + KC N +C C G+TGE C+ DI+ECL N +C+ Y C C F GR C + C S PCKNGG C S C C+ GY G +CE +N + P G C T C C G+ CQ + D + C NGG+C + + C C G+ G C
Sbjct: 621 CKPGFTGPQCKDEIDECQSNPCRNGGTCVDDENGFHCQCPEGFH--DPYCYSQ--VDECASNPCLHGTCRDDPNGYRCDCEPGWVGKNCDL-----------------------------------DRNDCL-----PSPCQNAGTCFDQLNGFTCKCRQGFRGNLCQVNINECASSPCLN---QGTCV-DGVASFTCLCEPPYSGPTCAELLTPCSPNPCANHASCVHTPDYLGYQCNCQPGWQGHLCNNDINECTSNPCKNRGTCTNTLGGYVCSCRAGYT-GPNCETDINDCSPNPCLNGGSCTDGVNSFRCSCLPGFTGARCATELNECQSVPCKNGG---TCTDYVNSYTCTCKPGFTGLLCETNVPDCTESSCFNGGTCTDGINGFKCTCRTGFTGDYCQYEVNECDSQPCLNGGICQDAMESYRCSCPKGYTGPRCQYPVDWCRPSNPCKNGGRCRQKDASFTCDCLGGW----------------------SGRYCDIP----GVSCEVAARQRGRQTDELCLHGGHCVNTGNTHYCKCP-----ADYTGSYCESQFDHCEEKPCLNGATCRSYMGGFTCDCMPGYEGNNCEREVNECQ--SHPCQNGGTCIDLVGHYICSCPPGTLGVLCEINEDDCATPSWPRGMPKCQNNGTCVDRVGGYRCNCPPGFTGERCEGDINECLSNPCNPSNSLDCIQLPNDYQCVCKPGFT-----GRGCQSRFSVCESQPCKNGGVCSLSGSSPPGYSCTCQLGYAGSNCERSMNCKELPCYNG---GSCTLTTRGARCTCIQGF----GGPLCQHRSNDGCSSKPCHNGGLCTEETSYPFFHCQCTNGWKGKRC 1378 HSP 6 Score: 144.436 bits (363), Expect = 3.069e-34 Identity = 156/563 (27.71%), Postives = 235/563 (41.74%), Query Frame = 1
Query: 1420 SNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYN-----HGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFN-DFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECP----KCVR-GTCNEN-----KCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCK---NGHKLAEDKRSCIPPNKKTCLDKDCVH--GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPG--FILSANSHSCQS----VCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
S G ++ C G C++ C C G+ G C +D C + C+ N + C C GF Q + C NG C + C CPPGY G NC + D C C + C + + C CL GY +TC+ P +C+ GTC++ +C C GF G CE+++++C + +C + + ++ C+C G AED C+ + + H G CFN+ C+C +G+ G C E+I++C C + S+ C C G +L +C S ++C + C C G+ G C+ D+DEC + + C+H CVN+ GS+ C C + R ++ N+ S PC+N C++ C C PGY G CE DI+EC+ + C+ G CR+ + C C PG+ CQI + P C NG C D C C GF G C ++D C + PC G C + S+ C C Y
Sbjct: 19 SEGLLCVDTHRPCENGGMCIDSRCLCRPGYIGSLCQ-HLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQ--DCSLVDACATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECLTGY----SGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFRGHNCEDNVDDCPGHKCMNNGICVDGVNTYNCQCPPEWTGQYCAEDVNECL-------MQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGY----TGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYQGKYCEVDIDECE----SNPCVNDGICRDMVNGFTCTCQPGFT----GTMCQIDIDECASTP-CQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNC-KPDPCH--HGTCVDGIASYTCNCEPGYT 551
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Match: notch1a (notch receptor 1a [Source:NCBI gene;Acc:30718]) HSP 1 Score: 214.542 bits (545), Expect = 4.056e-56 Identity = 241/775 (31.10%), Postives = 332/775 (42.84%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNNCNKNG-DCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFN-DFCHFISPCEHN-CTTINDNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHG-----QCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLC-----KNGKC-----DFNN-KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
C C GW G+ C E C HG + R F C C T C L+ S CQ G C + C C G+ G C +I+ CS +G CEH C+N + +FQCKC G++ + D C C T ++ +C C G++G FC + D+C C C++ I S+ C C +GF S C ++ C + KNG C +G C C G+ G C LDI+EC + +C + SF C C G+T ++ N +C+S+ C NGG C + C CP G G NCE N D C PC++ C + C C PGY + C C C+ G N C CP GF C + NEC + C + I S+ C C+ G R+C N CL CV+G C C++G+ G C +INEC + + C++ +KC+CM L C++V + C KNG DF + C C GW G+ C+VDI+EC+ N C N G + C CN F G C D C +PC NGG C + C C G+ G+ C EDI+EC ++G G C + +Y C CP G+ ++ C+I+T D C NGG C D C C GF G C DV+EC PC G C + YG++ C C Y +
Sbjct: 319 HCVCVNGWTGDDCS----ENIDDCASAACSHGATCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVSGKAICTCPPGYTGSACNQDIDECS---LGANPCEHGGRCLNT-KGSFQCKCLQGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICMPGYEGVFCQINSDDCASQPCLNSGKCIDKINSFHCECPKGF---SGSLCQVDVDECASTPCKNGAKCTDGPNKYTCECTPGFSGIHCELDINECASSPCHYGVCRDGVASFTCDCRPGYTGRLCETNINECLSQPCR----NGGTCQDRENAYICTCPKGTTGVNCEINIDDCKR-KPCDYGKCIDKINGYECVCEPGYSGSMCNINIDDCALNPCHNGGTCIDGV-NSFTCLCPDGFRDATCLSQHNECSSNPCIHGSCLDQINSYRCVCEAGWM----GRNC-DININECLSNPCVNGGTCKDMTSGYLCTCRAGFSGPNCQMNINECASNPCLNQGSCIDDVAGFKCNCM----LPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQCRCNPGFT-----GALCENDIDDCEPNPCSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVSAPCRNG--GNCTDCVNSYTCSCPAGFSGIN----CEINTPDCT-ESSCFNGGTCVDGISSFSCVCLPGFTGNYCQHDVNECDSR-PCQN-GGSCQDGYGTYKCTCPHGYTGL 1053 HSP 2 Score: 187.963 bits (476), Expect = 9.998e-48 Identity = 246/879 (27.99%), Postives = 350/879 (39.82%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCL----ELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSC--SRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFT-------------------------------LLSNGKCAINCL-------------NNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYN-HGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDL---MPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGH-----------------------KLAEDKRSCIPPNKKT----------CLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCS--LCKNGKC--DFNN-KCKCKTGWTGELCDVDIDECL-------------------------------LNQHKC-------QHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C C+ GW G+ C + +P C C +G + + C C C E C+NGGTC C+C + G CQ C S + G CV + C C GF +++ C + C G + + NC C + W G++C +DVDEC L P CQ C NTIG + C C G+T +G+ + C +NC+ N IC C G+ G C+ DIDEC + CEH C+N GSF C+C G+ +++ +C S C + CL+ GG C C PGY G C+ N PC ++ I+ ++ C C G+ D C C KC G N+ C+C GF+G+ CE DINEC + VC + + SF C C+ G+ + E+ C P T C K C +G+C + +C+C+ GY G C+ +I++C C++ S+ C C GF A S + CS C +G C N+ +C C+ GW G CD++I+ECL +N ++C Q +C++ + C+C LP+ G C CS PCKNGG C S+ C C G+ G +CE DINEC +G G C N G ++C C PG+ C+ D NP C NGGVC+D C C GF G C D+DEC APC + G C + S+ C C + +
Sbjct: 126 CRCQPGWSGKTCQLADP--CASNP---CANGGQCSAFESHYICTCPPNFHGQTCRQDVNECAVSPSPCRNGGTCINEVGSYLCRCPPEYTGPHCQRLYQPCLPSPCRSGG-----TCVQTSDTTHTCSCLPGFTGQTCEHNVDDCTQHACENGGRCIDGINTYNCHCDKHWTGQYCTEDVDECELSPNACQNGGTCHNTIGGFHCVCVNGWTGDDCSENIDDCASAACSHGATCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVSGKAICTCPPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKCLQGYEGPRCEMDVNECKSNPCQNDATCLDQIGGF----HCICMPGYEGVFCQINSDDCASQPCLNSGKCIDKINSFHCECPKGFSGSLCQVDVDECASTPCKNGAKCTDGP-NKYTCECTPGFSGIHCELDINECASSPCHYGVCRDGVASFTCDCRPGYTGRLCETNINECLSQPCRNGGTCQDRENAYICTCPKGTTGVNCEINIDDCKRKPCDYGKCIDKINGYECVCEPGYSGSMCNINIDDCALNPCHNGGTCIDGVNSFTCLCPDGF-RDATCLSQHNECSSNPCIHGSCLDQINSYRCVCEAGWMGRNCDININECLSNPCVNGGTCKDMTSGYLCTCRAGFSGPNCQMNINECASNPCLNQGSCIDDVAGFKCNCMLPYT-----GEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNG--GVCENLRGGFQCRCNPGFT----GALCENDIDDCEPNP-CSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVS-APC-RNGGNCTDCVNSYTCSCPAGF 974 HSP 3 Score: 171.4 bits (433), Expect = 1.240e-42 Identity = 229/794 (28.84%), Postives = 330/794 (41.56%), Query Frame = 1
Query: 781 IDNCVPD-CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG--------DCLNG-ICYCFSGWHGEDCSLDIDECK----YNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-TCNEN----KCKCPKGFAGLLCENDINEC---------LNQTICQHV--CTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQ-SVCSLCKNGKCDFNNK----------CKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCV---NSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDT-MCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGV 2859
ID+C + C G C+ C C G+ C+ E C+HG D+ + C+C NC + + C S C NGGTC C C GF G CQ+ IN C+ + C+N+G F+C C +G +N C C G + + S +C C GW+G+ C D++EC+ C +C N G +QC C GFT G N +++C N D +NG +C C +G+ GE C+ DIDEC N G CVN S+ C C +GF+ +IN C SC NGG C C C PG+ G+ C+ + PC++ +C C+C GY + + + + C G +C + C+C G+ G+ C+ C +C+H C + + CRC+ G+ + E C P N TC D C C GY G C ++INEC S C++ C++ +YKCSC G + C SV L +C FN C C G+ GE C+ D++ECL + +NCV + C C + G+ C + C +PCKNGG C N+K CKC+PGY+G SCE D C ++G C + + C+C PG+ CQ + NP C NGG C+ +S RC CP F+G+ C +
Sbjct: 678 IDDCALNPCHNGGTCIDGVNSFTCLCPDGFRDATCLSQHNECSSNP----CIHGSCLDQIN-SYRCVCEAGWMGRNCDININECLSNPCVNGGTCKDMTSGYLCTCRAGFSGPNCQMNINECA---------SNPCLNQGSCIDDVAGFKCNCMLPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQCRCNPGFT----GALCENDIDDCEPNPCSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVSAPCRNGGNCTDCVN---SYTCSCPAGFSGINCEINTPDCTESSC----FNGGTCVDGISSFSCVCLPGFTGNYCQHDVNECDSRPCQNGGSCQDGYGTYKCTCPHGYTGLNCQSLVRWCDSSPCKNGGSCWQQGASFTCQCASGWTGIYCDVPSVSCEVAARQQGVSVAVLCRHAGQCVDAGNTHLCRCQAGYTGSYCQEQVDECQPNPCQNGATCTDY------LGGYSCECVPGYHGMNCSKEINEC--LSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEIDIDDCSPSVDPLTGEPRC-FNGGRCVDRVGGYGCVCPAGFVGERCEGDVNECLSDPCDPSGSYNCVQLINDFRCECRTGYT-----GKRCETVFNGCKDTPCKNGGTCAVASNTKHGYICKCQPGYSGSSCEYDSQSCGSLRCRNGAT--CVSGHLSPRCLCAPGF----SGHECQTRMDSPCLVNP-CYNGGTCQPISDAPFYRCSCPANFNGLLCHI 1425 HSP 4 Score: 165.622 bits (418), Expect = 8.227e-41 Identity = 228/848 (26.89%), Postives = 335/848 (39.50%), Query Frame = 1
Query: 1015 SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAIN----CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKDK-----CKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYD-------LMP-------DKKTCKKLE--------CP-------------KCVRGTCNEN----------KCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCK---NGHKLAEDKRSCIPP---NKKTCLD----------------------KDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-----------------------LSANSHSCQ--------------------------SVCSLCKN-GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPI----SKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGG-----VCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICY---NTYGSFYCQCSSNYVLM---YDGTSCMTMK 2997
S C+NG C G C+CT GF G C+L+IN C+ + C + +G +F C C+ G+ + + C+ + C GT + C C +G G C ++D+C C C++ I Y+C C G+ S C IN LN C+ G C++G+ C C G+ C +EC N C++ S+ C C +G+ + IN +C+S C +NGG C KD C C G+ G NC+ N +PC + + I+D C+C+ Y L P + C++ E CP +CVR C +C+C GF G LCENDI++C N VC + + F C C G + AED C+ N C D DC CFN C+C G+ G C D+NEC C + G+YKC+C G+ S +CQ SV LC++ G+C D N C+C+ G+TG C +DEC N + C + G YSC C +P Y G +C ++ + C S PC+NGG C++ KC C G G CE DI++C + + C G C + G Y C+CP G++ + C+ + + +P +G + D RC C G+ G C + C + PC K G C NT + C+C Y YD SC +++
Sbjct: 533 STPCKNGAKCTDGPNKYTCECTPGFSGIHCELDINECA-----SSPCHYGVCRDGVASFTCDCRPGYTGRLCETNINECLSQPCRNGGTCQDRENAYICTCPKGTTGVNCEINIDDCKRKPCDYGKCIDKINGYECVCEPGY---SGSMCNINIDDCALNPCHNGGTCIDGVNSFTCLCPDGFRDATCLSQHNECSSNPCIHGSCLDQINSYRCVCEAGWMGRNCDININECLSNPC----VNGGTC-KDMTSGYLCTCRAGFSGPNCQMNINECASNPCLNQGSCIDDVAGFKCNCMLPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQCRCNPGFTGALCENDIDDCEPNPCSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVSAPCRNGGNCTDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTCVDGISSFSCVCLPGFTGNYCQHDVNECDSRPCQNGGSCQDGYGTYKCTCPHGYTGLNCQSLVRWCDSSPCKNGGSCWQQGASFTCQCASGWTGIYCDVPSVSCEVAARQQGVSVAVLCRHAGQCVDAGNTHLCRCQAGYTGSYCQEQVDECQPNPCQNGATCTDYLGGYSCEC-VPGY----HGMNCSKEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEIDIDDCSPSVDPLTGEPRCFNGGRCVDRVGGYGCVCPAGFV----GERCEGDVNECLSDPCDPSGSYNCVQLINDF-RCECRTGYTGKRCETVFNGC-KDTPC-KNGGTCAVASNTKHGYICKCQPGYSGSSCEYDSQSCGSLR 1355 HSP 5 Score: 159.458 bits (402), Expect = 5.596e-39 Identity = 209/733 (28.51%), Postives = 287/733 (39.15%), Query Frame = 1
Query: 1024 CQNGGTCF-----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKE---------ECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGS-YQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN-HGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCE--HNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNG---GKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCI-----------------------------------GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C+NGGTC C+C G+ G CQL S C E+++ C C F G++C ++ C GT EV S C+C + G C CL C+ CV T + + CSC GFT + +C + C G C++GI C+C W G+ C+ D+DEC+ + + C++ C N G F+C C +G+T N C S +C+ +G C C+CP G G C +D C +PC+ NC T + + K + C CP G+ G C DI+EC L C+H C NT GSF C+ C GY G RC+ D+NECK + C++ G + C CMPG+ NS C S L +GKC D N C+C G++G LC VD+DEC K C + Y+C C F G C L+ N+ SSPC G + C C+PGY G CE +INEC ++G G+C + YEC+C PGY C I+ D NP C NGG C D C CP GF C +EC PC + G C + S+ C C + ++
Sbjct: 110 CRNGGTCSLLTLDTFTCRCQPGWSGKTCQLADPCASNPCANGGQCSAF-----ESHYICTCPPNFH----GQTCRQDVNECAVSPSPCRNGGTCINEVGSYLCRCPPEYTGPHCQRLYQPCLPSPCRSGGTCVQTSDTTHTCSCLPGFTGQTCEHNVDDCTQHACENGGRCIDGINTYNCHCDKHWTGQYCTEDVDECELSPNACQNGGTCHNTIGGFHCVCVNGWTGDDCSENIDDCASAACS----HGATCHDRVASFFCECPHGRTGLLCHLDDAC-ISNPCQKGSNCDT-----------------NPVSGKAI--------------CTCPPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCK--------------------------------------CLQGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICMPGYEGVFCQINSDDCASQPCL-NSGKCIDKINSFHCECPKGFSGSLCQVDVDECASTPCKNGAKCTDGPNKYTCECTPGF-----SGIHCELDINECASSPCHYGVCRDGVASFTCDCRPGYTGRLCETNINECLSQPCRNGGTCQDRENAYICTCPKGTTGVNCEINIDDCKRKPCDYGKCIDKINGYECVCEPGY----SGSMCNINIDDCALNP-CHNGGTCIDGVNSFTCLCPDGFRDATCLSQHNECSS-NPC--IHGSCLDQINSYRCVCEAGWM 745
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Match: notch2 (notch receptor 2 [Source:ZFIN;Acc:ZDB-GENE-000329-4]) HSP 1 Score: 206.068 bits (523), Expect = 2.056e-53 Identity = 219/737 (29.72%), Postives = 326/737 (44.23%), Query Frame = 1
Query: 1024 CQNGGTC--------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTC--EHICVNEGE------NNFQCKCQSGF--QLDNDGKSCIKEECSKFGTTEVVSG---NCKCKQGWKGKFCNDDVDECLFPVC---QQICVNTIGSYQCSCREGFTLLSNGKCAINC-LNNCNKNGDCLNG-----ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIE---CLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN------KCKCPKGFAGLLCENDINEC-LNQTICQH--VCTNTIGSFFCRCKNGH---KLAEDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNK---------CKCKTGWTGELCDVDIDECLLNQHKCQHN-CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLK 3012
C+NGG C C C GF G+ C+++ NS TC + C N G+ + ++C+C G+ Q +C+ C+ G + +C C G+ G C +D DEC+ P+ + +CVNTIGSY+C+C+ GFT L G C + C G C +C+C G++G +C ++ID+C +H C++ C++ ++NCQC +T Q C ++ C NGG C + C C G+ G +C N PC T I+ + VCSC PG + + P + C+ N C CP G+ G C DI+EC + C+H C NT GSF C C G+ + +D C N TCLD Q + CIC G+ G C+ DINEC + C++ + C C GF +CQ C + C K C+C G+TG LC +I++C C H C++ ++ C C LP Y+ + C E+ C S PC+NGG+CV+ +C C+PG G++C+ + ++C +H G C + Y+C+C PGY + C + NP C +GG C D +C CP+G +G C D C R PC G C + CQC ++GT+C K L
Sbjct: 72 CKNGGECKVSVAGVPGSPSCVCPLGFAGEHCEIQKNS---------TCYPNNPCTNGGKCLLLPNDQYKCQCALGWTGQHCEQEDACLSSPCANKGICNALPNREYSCTCAPGFHGSRCLNDTDECVDPLVCKNKGVCVNTIGSYRCNCQPGFTGLDCGSPYFPCSPSPCQNGGTCRQTTETTYVCHCLPGFNGTNCEVNIDDCP-DHRCQNGATCMDGVNTYNCQCPPEWTGQFCTDDV--DECRLQPNACQNGGTCSNTRNGYNCVCVNGWSGLDCSENIDDCAAEPCTAGSTCIDRVASFVCSCPPGKTGLLCHIDDACISNPCKMGAHCDTNPVNGKFSCNCPSGYKGSTCAEDIDECVIGPNPCEHGGSCKNTEGSFTCNCAPGYTGPRCEQDINECGSNPCQNDATCLD------QIGDYTCICMPGFDGTHCENDINECLSSPCLNNGRCLDQVSRFVCECPQGFT----GETCQVDIDECASTPCHNGAKCLDRPNGYECECAEGFTGPLCMENINDC--EPQPCHHGKCIDGIATFHCDC-LPGYMGPI----CSEQIRECQSDPCQNGGRCVDMVNRYQCNCQPGTAGENCQINYDDCASNPCQH---GTCEDGINEYKCVCEPGYT----GERCADEINECSSNP-CQSGGTCEDKVNGFKCKCPVGTYGPLCLSGADRCIRM-PC--RHGECIGKQEGYLCQCEPG----WEGTNCDQEKNECLS 764 HSP 2 Score: 192.586 bits (488), Expect = 2.993e-49 Identity = 240/796 (30.15%), Postives = 351/796 (44.10%), Query Frame = 1
Query: 832 RCYCETGWFGERCVI----LEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLE-LRTC-SKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLD---NDGKSCIKEECSKFGTTE--VVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG----DCLNG-ICYCFSGWHGEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKS---CNIECLNGGLCDKD------KCKCPPGYIGHNC-EFNDFCHFISPCEHN--CTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDK-DCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKC---------DFNNKCKCKTGWTGELCD--------VDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD--TMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGI-CYNTYGSFYCQCSSNYVLMYDGTSCMTM 2994
C C G+ G C+ EP+ C K C+ G + F C C C E +R C S CQNGG C + +C C G G+ CQ+ + C+ + C+H +G N ++C C+ G+ + ++ C C GT E V CKC G G C D C+ C+ C+ Y C C G+ + + CL+N +NG D LN C C G+ G +C ++I+EC+ N + CV+ S+ C C +T K C+ K + C G+C CKC G+ G C E D C SPC++ C I + C C PGY + + C C GTC + C+C GF G CE +++EC N CT+ + S+ C+C G+ +R + +CL+ CV G S C C+ G+ G+ C ++NEC SH C++ C++ G++ C+C L N +C+S+ +LC KC + N +C C+ GWTG CD V +++ + C+H +C N ++ C C + G C + D C SSPC+NGG CV+ + CKCK G+ G +CE ++NECQ ++G G C + ++ C CPPG L C++ + P C NGG C D C CP GF G C DV+EC R PC I C S+ C+C L Y G C +M
Sbjct: 556 ECECAEGFTGPLCMENINDCEPQPCHHGK---CIDGIAT------FHCDCLPGYMGPICSEQIRECQSDPCQNGGRCVDMVNRYQCNCQPGTAGENCQINYDDCA-----SNPCQHGTCEDGINEYKCVCEPGYTGERCADEINECSSNPCQSGGTCEDKVNGFKCKCPVGTYGPLCLSGADRCIRMPCRHGECIGKQEGYLCQCEPGWEGTNCDQEKNECLSNPCQNGGTCNDRLNDYTCVCARGFAGFNCEININECESNPCMNQGTCVDGVNSYVCHCKPPYT----GKHCLEKLIPCASQPCQRRGVCQPSLDYTSYTCKCHSGWEGAQCTEDKDECK-KSPCQNGARCVNIVGSYRCECPPGYSGDNCQTNIDDCSSNPCRN--GGTCVDKVGRYLCECRAGFYGERCEEEVDECASNPCWNGGHCTDYVNSYTCQCPPGYDGINCERDIPDCTETSCLNNGTCVDGINHFS-CRCRQGFSGQYCQFELNECD--SHPCKNGGTCIDGLGTFHCNC----PLMYNGKTCESMVNLCSQIKCQNGGTCIQKEINWRCSCQPGWTGLYCDIPSMSCHAVALNKGVAENMVCKHAGHCKNIGNTHQCECQKGYT-----GSYCETEIDECLSSPCRNGGTCVDYQGGYDCKCKAGFQGVNCEYNVNECQSNPCRNG--GTCIDLINHFSCSCPPGTKGLQ----CEVDVDECAPEFGPRCKNGGQCVDGVGRYTCNCPPGFAGEHCEGDVNEC-RSGPCYSPGTIDCVPLINSYQCRCR----LGYTGQRCESM 1307 HSP 3 Score: 181.03 bits (458), Expect = 1.304e-45 Identity = 261/912 (28.62%), Postives = 346/912 (37.94%), Query Frame = 1
Query: 754 EVVCLNKPAIDNCVPDCGEHGIC-----VKSRCYCETGWFGERCV-----ILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQGR-----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL-------------------------------SNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDL---MPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKL---AEDKRSCIPP------------------------------NKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPG-FILSANSHSCQSVCSLCKNGKCDFNNK---CKCKTGWTGELCDVDIDECL-------------LNQHKC-------------------------QHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS------KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC 2985
E CL+ P C GIC + C C G+ G RC+ ++P +CK + + G + C C T +C CS CQNGGTC Q C C GF G C++ I+ C +H C N G +C+ V + NC+C W G+FC DDVDEC L P CQ C NT Y C C G++ L GK + C N C C +NG C C SG+ G C+ DIDEC + CEH C N GSF C C G+T + + +C S C + C C PG+ G +CE + SPC +N C VC C G+ D C C KC+ N +C+C +GF G LC +IN+C Q C + I +F C C G+ +E R C N C C HG C + KC+C+ GY G+RC ++INEC C + +KC C G + S + + + C++G+C + C+C+ GW G CD + +ECL LN + C Q CV+ SY C C P+ G+ CLEK C+S PC+ G C S CKC G+ G C ED +EC+ ++G C N G+Y C CPPGY CQ + D NP C NGG C D C C GF+G C +VDEC PC G C + S+ CQC YDG +C
Sbjct: 146 EDACLSSP--------CANKGICNALPNREYSCTCAPGFHGSRCLNDTDECVDPLVCKNKGVCVNTIG--------SYRCNCQPGFTGLDCGSPYFPCSPSPCQNGGTCRQTTETTYVCHCLPGFNGTNCEVNIDDCP---------DHRCQN-------------------GATCMDG---------VNTYNCQCPPEWTGQFCTDDVDECRLQPNACQNGGTCSNTRNGYNCVCVNGWSGLDCSENIDDCAAEPCTAGSTCIDRVASFVCSCPPGKTGLLCHIDDACISNPCKMGAHCDTNPVNGKFSCNCPSGYKGSTCAEDIDECVIGPNPCEHGGSCKNTEGSFTCNCAPGYTGPRCEQDINECGSNPCQNDATCLDQIGDYTCICMPGFDGTHCENDINECLSSPCLNNGRCLDQVSRFVCECPQGFTGETCQVDIDECASTPCHNGAKCLDRP-NGYECECAEGFTGPLCMENINDCEPQPCHHGKCIDGIATFHCDCLPGYMGPICSEQIRECQSDPCQNGGRCVDMVNRYQCNCQPGTAGENCQINYDDCASNPCQHGTCEDGINEYKCVCEPGYTGERCADEINECSSNPCQSGGTCEDKVNGFKCKCPVGTYGPLCLSGADRCIRMPCRHGECIGKQEGYLCQCEPGWEGTNCDQEKNECLSNPCQNGGTCNDRLNDYTCVCARGFAGFNCEININECESNPCMNQGTCVDGVNSYVCHCKPPYT-----GKHCLEKLIPCASQPCQRRGVCQPSLDYTSYTCKCHSGWEGAQCTEDKDECKKSPCQNG--ARCVNIVGSYRCECPPGY----SGDNCQTNIDDCSSNP-CRNGGTCVDKVGRYLCECRAGFYGERCEEEVDECAS-NPCWN-GGHCTDYVNSYTCQCPPG----YDGINC 985 HSP 4 Score: 172.94 bits (437), Expect = 4.042e-43 Identity = 228/792 (28.79%), Postives = 337/792 (42.55%), Query Frame = 1
Query: 826 KSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCL-ELRTCSKG-CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI------CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCK---NGHKLAEDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYS--------HICEH--FCMNTEGSYKCSCMPGFILSA-NSHSCQSVCSLCKNGK--CDFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSP----CKNGGKCVNS----KCKCKPGYNGDSCEEDINECQ-WPISKHGCIGECRNTFGNYECICPPGY--------LVLDDQKTCQISTKDTM-----------CNP------------------HCLNGGVCRDM---SRCYCPIGFHGIDCGVDVDEC 2874
+ +C C+ G GE C I + C HG D ++ C+C T C E+ CS CQ+GGTC +C+C G G C + C R M R E I EG + C+C+ G++ D + C+ C GT + C C +G+ G C +++EC C Q CV+ + SY C C+ +T + I C + C + G C + C C SGW G C+ D DECK + C++ CVN+ GS+ C+C G++ Q N C S C NGG C + C+C G+ G CE +PC + +CT ++ C C PGYD + PD L CV G N C+C +GF+G C+ ++NEC + C++ C + +G+F C C NG C N TC+ K+ N +C C+ G+ G CD C + +C+H C N +++C C G+ S + + + S C+NG D+ CKCK G+ G C+ +++EC N + C++ +SCSC G C D C+ CKNGG+CV+ C C PG+ G+ CE D+NEC+ P G I +C +Y+C C GY + L K C + + T C P CLNGG C ++ +C+CP+GF G C + + C
Sbjct: 629 RYQCNCQPGTAGENCQINYDDCASNP----CQHGTCEDGIN-EYKCVCEPGYTGERCADEINECSSNPCQSGGTCEDKVNGFKCKCPVGTYGPLCLSGADRCIR--MPCRHGECIGKQEG---YLCQCEPGWEGTNCDQEKNECLSNPCQNGGTCNDRLNDYTCVCARGFAGFNCEININECESNPCMNQGTCVDGVNSYVCHCKPPYTGKHCLEKLIPCASQPCQRRGVCQPSLDYTSYTCKCHSGWEGAQCTEDKDECKKSP-CQNGARCVNIVGSYRCECPPGYSGDNCQTNIDDCSSNPCR----NGGTCVDKVGRYLCECRAGFYGERCEEEVDECASNPCWNGGHCTDYVNSYTCQCPPGYDGINCERDIPDCTETSCLNNGTCVDGI-NHFSCRCRQGFSGQYCQFELNEC-DSHPCKNGGTCIDGLGTFHCNCPLMYNGKTCESMVNLCSQIKCQNGGTCIQKE------INWRCSCQPGWTGLYCDIPSMSCHAVALNKGVAENMVCKHAGHCKNIGNTHQCECQKGYTGSYCETEIDECLSSPCRNGGTCVDYQGGYDCKCKAGFQGVNCEYNVNECQSNPCRNGGTCIDLINHFSCSC-----PPGTKGLQCEVDVDECAPEFGPRCKNGGQCVDGVGRYTCNCPPGFAGEHCEGDVNECRSGPCYSPGTI-DCVPLINSYQCRCRLGYTGQRCESMVDLCQSKPCHNNGRCTTNSSSVHGYICTCPPGFSGFNCGNYEMFPCASLRCLNGGQCVEIKSRPQCHCPVGFTGTHCEMLTNHC 1391 HSP 5 Score: 170.629 bits (431), Expect = 2.319e-42 Identity = 237/859 (27.59%), Postives = 358/859 (41.68%), Query Frame = 1
Query: 781 IDNCV--PDCGEHGICVKSR-----CYCETGWFGERCVILEPELCKQRKLLFC-VHGCSFDKRKLD----FSCIC--GIKETQ-----NNCLELRTCSKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ----LDNDGKSCIKEECSKFGTTE-VVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN-------------------------------------HGCEH-LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHN-------CTTINDNMVCSCLPGYD-------LMPDKKTCKKLECPKCVRGTCNEN------KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGH-----KLAEDKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN---------KCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCV----NSKCKCKPGYNGDSCEEDINECQWPISKHGC--------IGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQC 2946
ID CV P+ EHG K+ C C G+ G RC ++ + C + C D LD ++CIC G T N CL S C N G C C+C +GF G+ CQ++I+ C+ N C++ N ++C+C GF ++N C + C + + + +C C G+ G C++ + EC CQ CV+ + YQC+C+ G + C IN C +N ++G C +GI C C G+ GE C+ +I+EC N C H C+ + CQC G+ K +C+S C NGG C+ C C G+ G NCE N I+ CE N C ++ VC C P Y L+P C C + RG C + CKC G+ G C D +EC ++ CQ+ C N +GS+ C C G+ + D S P N TC+DK C C++G+ G+RC+E+++EC C + SY C C PG+ + +C+ C C N C+C+ G++G+ C +++EC + H C++ C++ G++ C+C L + +G++C + CS C+NGG C+ N +C C+PG+ G C+ C G G C+N ++C C GY C+ + + +P C NGG C D C C GF G++C +V+ECQ PC + G C + F C C
Sbjct: 418 IDECVIGPNPCEHGGSCKNTEGSFTCNCAPGYTGPRC---------EQDINECGSNPCQNDATCLDQIGDYTCICMPGFDGTHCENDINECL-----SSPCLNNGRCLDQVSRFVCECPQGFTGETCQVDIDECASTPCHNGA---KCLDR-PNGYECECAEGFTGPLCMENI-NDCEPQPCHHGKCIDGIATFHCDCLPGYMGPICSEQIRECQSDPCQNGGRCVDMVNRYQCNCQPG---TAGENCQINYDDCASNPCQHGTCEDGINEYKCVCEPGYTGERCADEINECSSNPCQSGGTCEDKVNGFKCKCPVGTYGPLCLSGADRCIRMPCRHGECIGKQEGYLCQCEPGWEGTNCDQEKNECLSNPCQ----NGGTCNDRLNDYTCVCARGFAGFNCEIN-----INECESNPCMNQGTCVDGVNSYVCHCKPPYTGKHCLEKLIP----CASQPCQR--RGVCQPSLDYTSYTCKCHSGWEGAQCTEDKDEC-KKSPCQNGARCVNIVGSYRCECPPGYSGDNCQTNIDDCSSNPCRNGGTCVDK------VGRYLCECRAGFYGERCEEEVDECASNPCWNGGHCTDYVNSYTCQCPPGY----DGINCERDIPDCTETSCLNNGTCVDGINHFSCRCRQGFSGQYCQFELNEC--DSHPCKNGGTCIDGLGTFHCNCPLMY-----NGKTCESMVNLCSQIKCQNGGTCIQKEINWRCSCQPGWTGLYCDIPSMSCHAVALNKGVAENMVCKHAGHCKNIGNTHQCECQKGYT----GSYCETEIDECLSSP-CRNGGTCVDYQGGYDCKCKAGFQGVNCEYNVNECQS-NPC-RNGGTCIDLINHFSCSC 1214 HSP 6 Score: 144.436 bits (363), Expect = 3.020e-34 Identity = 182/644 (28.26%), Postives = 273/644 (42.39%), Query Frame = 1
Query: 1228 CIKEECSKFGTTEVVSGN----CKCKQGWKGKFCNDDVDECLFPVCQ-----QICVNTI-GSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG-----------ICYCFSGWHGEDCSLDIDECKYNH-GCEHLCVNVPG-SFNCQCHSGFTLQINKKKCISKSCN----IECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCT---TINDNMVCSCLPGY---------DLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPG--FILSANSHSCQSVCSLCKNGK-CDFNN-----KCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
CI E T V+S N C+C G+ G++C+ D C C+ ++ V + GS C C GF + C I + C N C NG C C GW G+ C + D C + + +C +P ++C C GF + +C++ + + C N G+C +C C PG+ G +C F SPC++ T T VC CLPG+ D PD + C V N C+CP + G C +D++EC L CQ+ C+NT +NG+ C+C +G+ G C E+I++C C++ S+ CSC PG +L +C + + CK G CD N C C +G+ G C DIDEC++ + C+H +C N+ GS++C+C P Y G C + + C S+PC+N C++ C C PG++G CE DINEC C+ G C + + C CP G+ +TCQ+ + P C NG C D C C GF G C ++++C+ PC G C + +F+C C Y+
Sbjct: 28 CIDHEKPCVNGTCVISSNGTHYCRCAPGFLGEYCHHS-DPCNLLYCKNGGECKVSVAGVPGSPSCVCPLGF---AGEHCEIQKNSTCYPNNPCTNGGKCLLLPNDQYKCQCALGWTGQHCEQE-DACLSSPCANKGICNALPNREYSCTCAPGF----HGSRCLNDTDECVDPLVCKNKGVCVNTIGSYRCNCQPGFTGLDCGSPYFPCSPSPCQNGGTCRQTTETTYVCHCLPGFNGTNCEVNIDDCPDHRCQNGATCMDGV----NTYNCQCPPEWTGQFCTDDVDECRLQPNACQNGGTCSNT--------RNGYN------------------------------CVCVNGWSGLDCSENIDDCAAEPCTAGSTCIDRVASFVCSCPPGKTGLLCHIDDAC--ISNPCKMGAHCDTNPVNGKFSCNCPSGYKGSTCAEDIDECVIGPNPCEHGGSCKNTEGSFTCNC-APGYT----GPRCEQDINECGSNPCQNDATCLDQIGDYTCICMPGFDGTHCENDINECL----SSPCLNNGRCLDQVSRFVCECPQGFT----GETCQVDIDECASTP-CHNGAKCLDRPNGYECECAEGFTGPLCMENINDCEP-QPCH--HGKCIDGIATFHCDCLPGYM 601 HSP 7 Score: 125.946 bits (315), Expect = 1.327e-28 Identity = 177/687 (25.76%), Postives = 277/687 (40.32%), Query Frame = 1
Query: 802 CGEHGICVKS------RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQ--GR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNK-----NGDCL----NGICYCFSGWHGEDCSLDIDECKY---------NHGCEHL--CVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMP---DKKTCKKLECPKCVRGT-----CNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS-KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGS---YKCSCMPGFI-LSANSHSCQSVCSL-CKNG----KCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSK-----CKCKPGYNGDSCEEDINECQWP 2643
C G+C S C C +GW G +C + E CK+ C +G + C C + +NC + CS C+NGGTC GR C+C GF G++C+ E++ C+ + C N G N++ C+C G+ N D C + C GT + +C+C+QG+ G++C +++EC C+ C++ +G++ C+C L+ NGK + +N C++ G C+ N C C GW G C + C N C+H C N+ + C+C G+T + + I + + C NGG C + CKC G+ G NCE+N +PC + T I+ ++ CSC PG + D C P+C G C CP GFAG CE D+NE C++G + C+P NS +C C+ GY G+RC+ ++ C+ C S Y C+C PGF + ++ SL C NG + +C C G+TG C++ + C+ C+NGG C+ + C+C PG++G++C+E C +P
Sbjct: 843 CQRRGVCQPSLDYTSYTCKCHSGWEGAQCTEDKDE-CKKSP---CQNGARCVNIVGSYRCECPPGYSGDNCQTNIDDCSSNPCRNGGTCVDKVGRYLCECRAGFYGERCEEEVDECA---------SNPCWNGGHCTDYVNSYTCQCPPGYDGINCERDIPDCTETSCLNNGTCVDGINHFSCRCRQGFSGQYCQFELNECDSHPCKNGGTCIDGLGTFHCNC----PLMYNGKTCESMVNLCSQIKCQNGGTCIQKEINWRCSCQPGWTGLYCDIPSMSCHAVALNKGVAENMVCKHAGHCKNIGNTHQCECQKGYTGSYCETE-IDECLSSPCRNGGTCVDYQGGYDCKCKAGFQGVNCEYNVNECQSNPCRNGGTCIDLINHFSCSCPPGTKGLQCEVDVDECAPEFGPRCKNGGQCVDGVGRYTCNCPPGFAGEHCEGDVNE---------------------CRSGPCYSPGTIDCVP---------------LINSYQCRCRLGYTGQRCESMVDLCQSKPCHNNGRCTTNSSSVHGYICTCPPGFSGFNCGNYEMFPCASLRCLNGGQCVEIKSRPQCHCPVGFTGTHCEMLTNHCV---------------------------------------------CQNGGTCMPDESNKFSCRCPPGFSGETCQETPPSCPYP 1430
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Match: notch3 (notch receptor 3 [Source:ZFIN;Acc:ZDB-GENE-000329-5]) HSP 1 Score: 202.986 bits (515), Expect = 1.630e-52 Identity = 224/720 (31.11%), Postives = 318/720 (44.17%), Query Frame = 1
Query: 1018 KGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN--DGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDECLFP---VCQQICVNTIGSYQCSCREGFT----LLSNGKCAIN-CLN--NCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECP------------KCVRGTCNENK------------CKCPKGFAGLLCENDINEC-LNQTICQHV--CTNTIGSFFCRCKNGHKLAE---DKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSA---NSHSCQSVCSLCKNG-KC-DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
+ C+NGG C RC C G+ G CQ ++ C R N V + C CQ GF+ + +C C+ T NC C G++GK C +D+DEC P + IC+NT GS++C C G++ + CA + CLN C++ GD C C G+ G +C ++D+C H C + +CV+ ++NCQC +T Q + +C+ + C NGG C C C G+ G +C N I+D C G D+ ECP CV CNE C CP GF G C D++EC + C+H C NT GSF C+C G+ D C+ N TCLD+ CIC GY+GK C+ DI+EC+ + + C + + C+C PGF + + C S + C+NG KC D N +C+C G+ G LC+ +ID C C H CV+ SY+C+C P Y G C + + C S+PC+NGGKCV+ C+C+ G +G +CE + ++C +G C++ YEC+C PG+ C+ + NP C NGG C D C CP GFH C VDEC PC L G C + + C C +V
Sbjct: 29 RPCENGGMCIDSRCLCRPGYIGSLCQ-HLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQDCSLVDACATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECLTGYSGRTCEVPTQPCAPSQCLNGGTCHQTGD-HTYECACLPGFRGHNCEDNVDDCP-GHKCMNNGICVDGVNTYNCQCPPEWTGQYCAEDVNECLMQP--NACHNGGTCFNTIGGHTCVCVNGWTGDDCSEN---------------IDDCATAVCFNGATCH-DRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDR------IGEFTCICMPGYQGKYCEVDIDECESNPCVNDGICRDMVNGFTCTCQPGFTGTMCQIDIDECAS--TPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNC--KPDPCHHGTCVDGIASYTCNCE-PGYT----GYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGI---CKDGINRYECVCKPGFT----GPQCKDEIDECQSNP-CRNGGTCVDDENGFHCQCPEGFHDPYCYSQVDECAS-NPC--LHGTCRDDPNGYRCDCEPGWV 701 HSP 2 Score: 197.208 bits (500), Expect = 1.225e-50 Identity = 231/789 (29.28%), Postives = 347/789 (43.98%), Query Frame = 1
Query: 802 CGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKL-DFSCICGIKETQNNCLELRTCSKG-CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT---TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCL---NNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK----YNHGCEHLCVNVPGSFNCQCHSGFTLQI--NKKKCISKSCNIECLNGGLCDKDK------CKCPPGYIGHNCEFN-DFCHF-ISPCEH--NCTTINDNMVCSCLPGYDLMP---DKKTCKKLECPKCVRGTC----NENKCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGH-----KLAEDKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH-FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKN------GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHN-CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C G+C+ SRC C G+ G C L+P C + L S + ++C+C +C + C+ C NG C C C G++G C+ +I+ C + G IC+N +F+C+C +G+ + + C +C GT T + C C G++G C D+VD+C C ICV+ + +Y C C +T + CL N C+ G C N I C C +GW G+DCS +ID+C +N C + SF C+C G T + C+S CN G +CD + C CP G++G C + D C +PCEH C + C C GY D C + C TC E C C G+ G CE DI+EC N + +C + + F C C+ G ++ D+ + P N C+D+ + +C C G+ G+ C+ +I+ CK C H C++ SY C+C PG+ + C++ + C + GKC D NK C+C+ G +G C+++ D+C N C + C + Y C C F G C ++ D C S+PC+NGG CV+ + C+C G++ C ++EC H G CR+ Y C C PG++ K C + D + +P C N G C D C C GF G C V+++EC +PC +G C + SF C C Y
Sbjct: 31 CENGGMCIDSRCLCRPGYIGSLCQHLDP--CHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQDCSLVDACATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRK--PGKCLNGGICMNT-HGSFRCECLTGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFRGHNCEDNVDDCPGHKCMNNGICVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGA---TCHDRVASFFCECPVGKTGLLCHLDDACVSNPCN----EGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYTGPRCEIDINECLSMPCQN--DATCLDRIGEFTCICMPGYQGKYCEVDIDECESNPCVNDGICRDMVNGFTCTCQPGFTGTMCQIDIDECASTPCQNGAKCIDRPNGY------ECRCAEGFEGRLCESNIDNCKP--DPCHHGTCVDGIASYTCNCEPGYT----GYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINFDDCASN--PCDYGICKDGINRYECVCKPGFT-----GPQCKDEIDECQSNPCRNGGTCVDDENGFHCQCPEGFHDPYCYSQVDECASNPCLH---GTCRDDPNGYRCDCEPGWV----GKNCDLDRNDCLPSP-CQNAGTCFDQLNGFTCKCRQGFRGNLCQVNINECAS-SPCLN-QGTCVDGVASFTCLCEPPY 776 HSP 3 Score: 185.267 bits (469), Expect = 5.585e-47 Identity = 232/819 (28.33%), Postives = 330/819 (40.29%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTC----FQGR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT----LLSNGKCAINCLNNCNKNGDCLNGI-CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL-----QINKKKCISKSCNIECLNGG----LCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-TCNENK----CKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE---DKRSCIPP---NKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCD-----------FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC---VNS-KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPC--------------------------------------------DKL---RGICYNTYGSFYCQCSSNYVLMY 2970
C C GW G+ C E C +G + R F C C + +T C L+ S C G C GR C C GF G C +++ CS +G CEH CVN E +FQC+C G+ + + D C+ C T + C C G++GK+C D+DEC C IC + + + C+C+ GFT + +CA N K D NG C C G+ G C +ID CK + CV+ S+ C C G+T Q+N+ C S C NGG L +K C+C G G NCE N +PC++ C + C C PG+ K + + C G TC +++ C+CP+GF C + ++EC + C + + C C+ G D+ C+P N TC D Q C C+ G+RG C +INEC + + C++ S+ C C P + + +C + + C C +C C+ GW D CL +C + S+ CSC LP + R E N+ S PCKNGG C VNS C CKPG+ G CE ++ +C +G G C + ++C C G+ CQ + P CLNGG+C+D RC CP G+ G C VD C+ PC D+L G C NT + YC+C ++Y Y
Sbjct: 276 CVCVNGWTGDDCS----ENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECS---IGANPCEHFGKCVNT-EGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYQGKYCEVDIDECESNPCVNDGICRDMVNGFTCTCQPGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNCKPDPCHHGTCVDGIASYTCNCEPGYTGYRCENQLNE--CHSNPCQ----NGGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYECVCKPGFTGPQCKDEIDECQSNPCRNGGTCVDDENGFHCQCPEGFHDPYCYSQVDECASNPCLHGTCRDDPNGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCFD------QLNGFTCKCRQGFRGNLCQVNINECASSPCLNQGTCVDGVASFTCLCEPPY----SGPTCAELLTPCSPNPCANHASCVHTPDYLGYQCNCQPGWQ--------DPCLNGG-----SCTDGVNSFRCSC-LPGF---TGARCATELNECQSVPCKNGGTCTDYVNSYTCTCKPGFTGLLCETNVPDCTESSCFNG--GTCTDGINGFKCTCRTGFT----GDYCQYEVNECDSQP-CLNGGICQDAMESYRCSCPKGYTGPRCQYPVDWCRPSNPCKNGGRCRQKDASFTCDCLGGWSGRYCDIPGVSCEVAARQRGRQTDELCLHGGHCVNTGNTHYCKCPADYTGSY 1046 HSP 4 Score: 178.333 bits (451), Expect = 8.781e-45 Identity = 214/750 (28.53%), Postives = 307/750 (40.93%), Query Frame = 1
Query: 955 FSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQ---SGFQLDNDGKSCIKEECSKFGT-TEVVSGN-CKCKQGWKGKFCNDDVDECLFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCL---NGI-CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECP----------KCVR----------------------GTC----NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHK--LAEDKRSCIPPNKKTCLDKDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCK-------NGKC---DFNNKCKCKTGWTGELCDVDIDECLLNQHK--------CQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD------TMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDEC 2874
F+C C T C +++ C S CQNG C C+C EGFEG C+ I++C C H +G ++ C C+ +G++ +N C C G ++V+ C+C+ G G C + D+C C IC + I Y+C C+ GFT C +N C G C+ NG C C G+H C +DEC N C + P + C C G+ + +++ C+ C N G C + CKC G+ G+ C+ N SPC + T ++ + C C P Y TC +L P CV G+C N +C C GF G C ++NEC C++ CT+ + S+ C CK G L E +P DC CFN KC C++G+ G C ++NEC + C + SY+CSC G+ CQ C+ G+C D + C C GW+G CD+ C + + C H +CVN+ ++ C C + G C + D C PC NG C + C C PGY G++CE ++NECQ ++G G C + G+Y C CPPG L + C+I+ D P C N G C D RC CP GF G C D++EC
Sbjct: 467 FTCTCQPGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNCKP-----DPCHHGTCVDGIASYTCNCEPGYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYECVCKPGFTGPQCKDEIDECQSNPCRNGGTCVDDENGFHCQCPEGFHDPYCYSQVDECASNPCLHGTCRDDPNGYRCDCEPGWVGKNCDLDRNDCLPSPCQ----NAGTCFDQLNGFTCKCRQGFRGNLCQVNINECASSPCLNQGTCVDGVASFTCLCEPPYS----GPTCAELLTPCSPNPCANHASCVHTPDYLGYQCNCQPGWQDPCLNGGSCTDGVNSFRCSCLPGFTGARCATELNEC-QSVPCKNGGTCTDYVNSYTCTCKPGFTGLLCETN---VP---------DCTESSCFNGGTCTDGINGFKCTCRTGFTGDYCQYEVNECDSQPCLNGGICQDAMESYRCSCPKGYT----GPRCQYPVDWCRPSNPCKNGGRCRQKDASFTCDCLGGWSGRYCDIPGVSCEVAARQRGRQTDELCLHGGHCVNTGNTHYCKCPADYT-----GSYCESQFDHCEEKPCLNGATCRSYMGGFTCDCMPGYEGNNCEREVNECQSHPCQNG--GTCIDLVGHYICSCPPGTLGV----LCEINEDDCATPSWPRGMPKCQNNGTCVDRVGGYRCNCPPGFTGERCEGDINEC 1175 HSP 5 Score: 148.673 bits (374), Expect = 1.329e-35 Identity = 223/847 (26.33%), Postives = 335/847 (39.55%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCK----------------QRKLLFCVHGCSFDKRKLDF--------------------SCICGIKETQNNCL-ELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-------CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPP---------NKKTCLDKDCVHG-QCFNSK----CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKC---------KCKTGWTGELCDVDIDECLL-----NQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPC--KNGGKCV----NSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPH-------CLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICY--NTYGSFYCQCSSNY 2958
IDNC PD HG CV C CE G+ G RC E +L + + + C HG S +++F C+C T C E+ C S C+NGGTC CQC EGF C +++ C+ + C H + N ++C C+ G+ N D C+ C GT ++ CKC+QG++G C +++EC C Q CV+ + S+ C C ++ + + C N C D L C C GW D C N G C + SF C C GFT + +++ ++ C NGG C + C C PG+ G CE N S C + CT + C+C G+ + + + C+ G +C CPKG+ G C+ ++ C C++ C SF C C G R C P + D+ C+HG C N+ C C + Y G C+ + C++ + C + G + C CMPG+ ++C+ + C++ C C C G G LC+++ D+C KCQ+N CV+ G Y C+C F +G + N+ S+PC N C+ + +C CKPG+ G C+ + C+ K+G G C + + PPGY TCQ+ + C C NGG C +RC C GF G C ++ PC G+C +Y F+CQC++ +
Sbjct: 522 IDNCKPDPCHHGTCVDGIASYTCNCEPGYTGYRC---ENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYECVCKPGFTGPQCKDEIDECQSNPCRNGGTCVDDENGFHCQCPEGFHDPYCYSQVDECA-----SNPCLHGTCRDDPNGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCFDQLNGFTCKCRQGFRGNLCQVNINECASSPCLNQGTCVDGVASFTCLCEPPYSGPTCAELLTPCSPNPCANHASCVHTPDYLGYQCNCQPGWQ--------DPC-LNGGS---CTDGVNSFRCSCLPGFTGARCATE-LNECQSVPCKNGGTCTDYVNSYTCTCKPGFTGLLCETNVPDCTESSCFNGGTCTDGINGFKCTCRTGFTGDYCQYEVNECDSQPCLNGGICQDAMESYRCSCPKGYTGPRCQYPVDWCRPSNPCKNGGRCRQKDASFTCDCLGGWS----GRYCDIPGVSCEVAARQRGRQTDELCLHGGHCVNTGNTHYCKCPADYTGSYCESQFDHCEEKPCLNGATCRSYMGGFTCDCMPGY----EGNNCEREVNECQSHPCQNGGTCIDLVGHYICSCPPGTLGVLCEINEDDCATPSWPRGMPKCQNNGTCVDRVGGYRCNCPPGFTGERCEG----DINECLSNPCNPSNSLDCIQLPNDYQCVCKPGFTGRGCQSRFSVCESQPCKNG--GVCSLSGSS-----PPGYSC-----TCQLGYAGSNCERSMNCKELPCYNGGSCTLTTRGARCTCIQGFGGPLCQHRSNDGCSSKPCHN-GGLCTEETSYPFFHCQCTNGW 1322 HSP 6 Score: 143.665 bits (361), Expect = 4.287e-34 Identity = 156/563 (27.71%), Postives = 235/563 (41.74%), Query Frame = 1
Query: 1420 SNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYN-----HGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFN-DFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECP----KCVR-GTCNEN-----KCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCK---NGHKLAEDKRSCIPPNKKTCLDKDCVH--GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPG--FILSANSHSCQS----VCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
S G ++ C G C++ C C G+ G C +D C + C+ N + C C GF Q + C NG C + C CPPGY G NC + D C C + C + + C CL GY +TC+ P +C+ GTC++ +C C GF G CE+++++C + +C + + ++ C+C G AED C+ + + H G CFN+ C+C +G+ G C E+I++C C + S+ C C G +L +C S ++C + C C G+ G C+ D+DEC + + C+H CVN+ GS+ C C + R ++ N+ S PC+N C++ C C PGY G CE DI+EC+ + C+ G CR+ + C C PG+ CQI + P C NG C D C C GF G C ++D C + PC G C + S+ C C Y
Sbjct: 19 SEGLLCVDTHRPCENGGMCIDSRCLCRPGYIGSLCQ-HLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQ--DCSLVDACATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNTHGSFRCECLTGY----SGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFRGHNCEDNVDDCPGHKCMNNGICVDGVNTYNCQCPPEWTGQYCAEDVNECL-------MQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGY----TGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYQGKYCEVDIDECE----SNPCVNDGICRDMVNGFTCTCQPGFT----GTMCQIDIDECASTP-CQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNC-KPDPCH--HGTCVDGIASYTCNCEPGYT 551 HSP 7 Score: 95.1301 bits (235), Expect = 3.843e-19 Identity = 78/233 (33.48%), Postives = 110/233 (47.21%), Query Frame = 1
Query: 2317 CKNGKCDFNNKCKCKTGWTGELCDVDIDECL----LNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP-HCLNGGVCRDMS----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
C+NG +++C C+ G+ G LC +D C LN C+ NS Y+C C F G+ C + +SPC NG +C N C C PGY G +C DI+EC+ P C+ G C NT G++ C C GY +TC++ T+ C P CLNGG C C C GF G +C +VD+C + + GIC + ++ CQC + Y
Sbjct: 31 CENGGMCIDSRCLCRPGYIGSLCQ-HLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRGFR-----GQDCSLVDACATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRKPGK---CLNGGICMNTHGSFRCECLTGY----SGRTCEVPTQP--CAPSQCLNGGTCHQTGDHTYECACLPGFRGHNCEDNVDDCPGHKCMNN--GICVDGVNTYNCQCPPEWTGQY 246 HSP 8 Score: 80.1073 bits (196), Expect = 1.191e-14 Identity = 138/532 (25.94%), Postives = 198/532 (37.22%), Query Frame = 1
Query: 793 VPDCGEH-----GICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC---LELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQL-----EINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQS---GFQLDNDGKSCIKEECSKFGTTEVVSG--NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTL-----LSNGKCAINC----LNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN--HGCEHL-CVNVPGSFNCQCHSGFTLQINKKKCISKSCNIE---CLNGGLCDKD-------KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHIC 2214
VPDC E G C +C C TG+ G+ C E Q C++G + C C T C ++ S C+NGG C Q C C G+ G C + E+ + RG+ + C H CVN G ++ CKC + G ++ C ++ C T G C C G++G C +V+EC CQ C++ +G Y CSC G TL ++ CA + C NG C++ + C C G+ GE C DI+EC N + L C+ +P + C C GFT + C S+ E C NGG+C C C GY G NCE +M C LP Y+ C RG +C C +GF G LC++ N+ + C + +CT F C+ C +G++GKRC++ C
Sbjct: 888 VPDCTESSCFNGGTCTDGINGFKCTCRTGFTGDYCQYEVNECDSQP----CLNGGICQDAMESYRCSCPKGYTGPRCQYPVDWCRPSNPCKNGGRCRQKDASFTCDCLGGWSGRYCDIPGVSCEVAARQRGRQTDELCLHGGHCVNTGNTHY-CKCPADYTGSYCESQFDHCEEKPCLNGATCRSYMGGFTCDCMPGYEGNNCEREVNECQSHPCQNGGTCIDLVGHYICSCPPG-TLGVLCEINEDDCATPSWPRGMPKCQNNGTCVDRVGGYRCNCPPGFTGERCEGDINECLSNPCNPSNSLDCIQLPNDYQCVCKPGFT----GRGCQSRFSVCESQPCKNGGVCSLSGSSPPGYSCTCQLGYAGSNCE-------------------RSMNCKELPCYN---------GGSCTLTTRGA----RCTCIQGFGGPLCQHRSNDGCSSKPCHNGGLCTEETSYPFFHCQ------------------------------------CTNGWKGKRCEQKTGSSAPLPSPC 1341
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 219.164 bits (557), Expect = 1.707e-57 Identity = 224/720 (31.11%), Postives = 325/720 (45.14%), Query Frame = 1
Query: 1000 ELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQ-MGNRTCEHICVNEGENNFQCKCQSGF-----QLDNDGKSCIKEECSKFGT--TEVVSGN--CKCKQGWKGKFCNDDVDECLFPV--CQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFIS-PCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
E + CQNGGTC C C G+ G+ C I+ C+ TC + F C+C G LDN +CI C++ T V+G C C G+ G CN+DVDEC C+ C NT+GS+QC+C +G+ + +C I+ CL+N C + CL+ I C C G++G C D+DEC +G + C++ P S+ CQC GFT + + +CI C+ G+ C C PGY G C+ ND +S PC++ CT + +C+C G + + C G C + +C C G+ G +C +I+EC + C++ C + I F C C +G+ C+ C C+HG C + KC C +G+ G CD + NEC+ + C + G+Y C+C GF + C++V + C C +CK C GW G+ C++D++EC+ + C N+NGSY C+C P Y GR C D C +PC NGG C + C C G+ G CEEDINEC K+G C + +Y C C PG+ + C+ +T D C NGG C D C CP GF G C D++EC PC G C ++YG++ C C Y +
Sbjct: 226 ECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVAS-----FFCECPHGRTGLLCHLDN---ACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQGY---AGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPGFNGNLCQHDVDECASTPCKNGAK--CLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTCKDGIATF-TCLCRPGYTGRLCD-NDINECLSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNP-CRNGGTCKDKINGFTCVCPDGYH----DHMCLS-EVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGF----SGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCK-PGYA----GRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNG--ANCTDCVNSYTCTCQPGFSGIH----CENNTPDCT-ESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDS-KPCLN-GGTCQDSYGAYKCTCPQGYTGL 906 HSP 2 Score: 199.134 bits (505), Expect = 3.566e-51 Identity = 229/782 (29.28%), Postives = 329/782 (42.07%), Query Frame = 1
Query: 835 CYCETGWFGERC----------VILEPELCKQRKLLF---CVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNI-ECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSK------CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK---------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVC---RDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKL--------RGICYNTYGSFYCQCSSNYVLMY 2970
C C GW GE C C R F C HG + LD +CI N C E C NG + C C G+ G C +++ CS +G CEH C N +FQC C G+ + + D C+ C T ++ C C G+ G C DVDEC C+ C++ SY C C EGFT + C+ + G C +GI C C G+ G C DI+EC + C++ C + + C C G T + N C S C+ +C++ D +C C PGY G C N +PC + C + C C GY + C+ GTC++ KC C G++G C+ + NEC N + C + G++ C C+ G A + P + C + G+C S+ C C G++G+ C+ D+NEC C NT GSYKC+C PG+ A H C++ C+ C C C G+ G C+ DI+EC N K NC + SY+C+C F G C C+ S C NGG C++ C+C PG+ G+ C+ DINEC +G G C++++G Y+C CP GY L+ CQ + +P C NGG C + RC C G+ G+ C V C+ A + G+C +T + +C+C + Y Y
Sbjct: 249 CVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNACI------SNPCNEGSNCDTNPVNG----KAICTCPPGYTGPACNNDVDECS---LGANPCEHGGRCTNT-LGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPGFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTCKDGIATFTCLCRPGYTGRLCDNDINEC-LSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDK--IDGYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKINGFTCVCPDGYHDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGAICEAVLAPCSGSPCKNG----GRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCKPGY---AGRH-CETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGF-----SGIHCENNTPDCTESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDSKPCLNG--GTCQDSYGAYKCTCPQGYTGLN----CQNLVRWCDSSP-CKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSY 993 HSP 3 Score: 196.438 bits (498), Expect = 2.815e-50 Identity = 232/808 (28.71%), Postives = 330/808 (40.84%), Query Frame = 1
Query: 1024 CQNGGTC-----------------------------------FQGRCQCTEGFEGDQCQLEINSCS---------------------RGQMGNRTCEH--------ICVNEG------ENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL-------------------------------SNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN--------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNSK------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
C+NGGTC Q C+C GF G C+ +IN CS + + R CE C+N G + +++C C GF N + C C GT V + NC+C W G++C +DVDEC L P CQ C NT G Y C C G+T +G+ + C N CN+ +C +NG IC C G+ G C+ D+DEC + CEH C N GSF C C G+ +I+ +C+S C + + +C C PG+ G+ C+ + +PC++ C ++ C C G+ ++ + C GTC + C C G+ G LC+NDINECL+Q CQ+ CT+ + C C G + N C C +G+C + +C C+ GY GK C+ +I+EC C + + C C G+ + H C S + C + C KC C GW+G CDV+ +EC N C + G+Y C+C F G C CS SPCKNGG+C S+ C+C PG+ G +CE D+NEC ++G + C+NT G+Y+C C PGY + C+ D NP C NGG C D M C CP GF G C D++EC PC K C + S+ C C + ++
Sbjct: 48 CRNGGTCELLSSVSDYRCDSCQQADPCASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGSYRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPGFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSQP-CQNGGQCTDRENGYICTCPKGTTGVNCET-----NLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKINGFTCVCPDGY----HDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGF-----SGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAM--CQNTNGSYKCNCKPGYA----GRHCETDIDDCQPNP-CHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECAS-NPC-KNGANCTDCVNSYTCTCQPGFSGIH 831 HSP 4 Score: 175.252 bits (443), Expect = 1.140e-43 Identity = 215/781 (27.53%), Postives = 317/781 (40.59%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCL-ELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFG----------------TTEV----------------------VSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN----GDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK------CKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDLM---PDKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQHV-CTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-----------------------LSANSHSCQ--------------------------SVCSLCKN-GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCI-------GECRNTFGNYECICPPGYL 2721
+C C G+ G RC I E C + + + +F CIC N C ++ C S C+NG C G CQCTEGF G C+ +IN C TC+ +G F C C+ G+ DND C+ + C G TT V + G C C+ G+ GK CN ++DEC C+ C + I + C C +G+ + ++ +N CN N G C +GI C C +GW G +C ++ +EC+ N C + C ++ G++ C C +GF+ I + ++ C NGG C + + C+CPPG+ G CE + PC + C N + C+C PGY D C+ C G+C++ C CP GF G CE DINEC + CT+ + S+ C C+ G + + DC CFN C C G+ G C DINEC + C ++ G+YKC+C G+ + N + C+ + LC+N G C D N C+C+ G+TG C+ +DEC N + C + G YSC C ++ G +C E+ + C S PC NGG C++ KC C G G CE ++++C P + G+C + G Y CICPPG++
Sbjct: 365 QCNCPQGYAGPRCEIDVNECLSNP----CQNDATCLDQIGEFQCICMPGFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTCK-----DGIATFTCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKINGFTCVCPDGY----HDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNP-CMNGGTCKDMTGAYICTCRAGFSGAI-CEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHN--GGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENN----------TPDCTESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCEC-----VAGYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCT-PFYDSVSLEPKCFNNGKCIDRVGGYNCICPPGFV 1112 HSP 5 Score: 138.272 bits (347), Expect = 2.665e-32 Identity = 198/732 (27.05%), Postives = 291/732 (39.75%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCL-ELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQ-MGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH-------NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQHV-----------CTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQSVC-SLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTV----------DGRSCLEKNDSCSS-PCKNGGKC----------------------------VNSKCKCKPGYNGDSCE 2616
+D+C + ++G C+ C CE G+ G+ C I E C +G + + F+C+C + CL E+ C+ GTC G +C C G+ G C + N C M TC+ + + C C++GF + C C G + + + +C+C GW+G+ C D++EC+ C+ +C NT GSY+C+C+ G+ +C N C+ G C +GI C C +G+ G C DI+EC N +G C + S+ C C GF+ + N C SC NGG C + C+CPPG+ G+ C+ H I+ C+ C C+C GY + + + + C G T N +C+C G+ G+ C+ C Q V C +T + FCRC+ G+ + E C P N TC D C C +GY G C E+INEC SH C + C++ +YKCSC G N C S+ KC FNN C C G+ GE C+ D++ECL N + NC+ Y C C F + + R C D C PC+NGG C V S C +P YNG +C+
Sbjct: 532 LDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNP----CRNGGTCKDKINGFTCVCPDGYHDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDM-----TGAYICTCRAGFSGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGAN--CTDCVNSYTCTCQPGFSGIHCENNTPDCTESSC----FNGGTCIDGINTFSCQCPPGFTGNYCQ-----HDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTD------YLGGYSCECVAGYHGVNCSEEINEC--LSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKC-FNNGKCIDRVGGYNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFTGTVLLLLGRPKVLLPRRRCDSVVDGCKGLPCRNGGTCAVASNTERGFICKCPPVSRSGSFLPLYPVVSPCASRPCYNGGTCQ 1234 HSP 6 Score: 74.7146 bits (182), Expect = 9.664e-13 Identity = 67/203 (33.00%), Postives = 97/203 (47.78%), Query Frame = 1
Query: 2437 CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPH-CLNGGVCRDMS----RCYCPIGFHGIDCGVDVDECQRYAPCDKLR--GICYNTYGSFYCQCSSNYVLMY---DGTSCMTMKEA 3003
CVN+ +C L +S SC + + S+PC NGGKC+ + CKC G++G +C++DINEC ++G G+C N FG+Y C C + + C+ CNP CLNGG CR C C GF G +C ++D+C P + R G C + ++ CQC ++ Y D C M A
Sbjct: 43 CVNNPCRNGGTCELLSSVSDYRCDSCQQADPCASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNG--GQCLNEFGSYRCNCQNRFT----GRNCE--EPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDC----PSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNA 233
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: fto (FTO alpha-ketoglutarate dependent dioxygenase [Source:Xenbase;Acc:XB-GENE-972564]) HSP 1 Score: 216.853 bits (551), Expect = 9.720e-57 Identity = 250/878 (28.47%), Postives = 363/878 (41.34%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG--CQNGGTC--FQG--RCQCTEGFEGDQCQLEINSCSRGQ-MGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFT-------------------------------LLSNGKCAINCLNN-------------CNKNGDCLNGICYCFSGWHGEDCSLDIDECKY-NHGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCN--------------------------IE--------CLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAE-----------------------DKRSCIPPNK----------KTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKC----------DFNN-KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C C GW G C ++ C + C +G + + ++C C T C +++ C C+NGGTC G RCQC G+ G +C+ CS M TC E ++C C GF N + C +C GT V + NC+C W G+FC +DVDEC L P CQ C N+ G Y C C G++ + GK + C N C+ N IC C SG+ G C+ DIDEC ++ CEH CVN GSF C+C GFT +++ +C+S+ C IE C+N G C ++ C CPPG+ G C+ + +PC++ C C C G+ + ++ E P C GTC + C C G+ G +C + I+ECL N + + C + + + C C G + ++ CI P C++ C+HG C + KC+C+ G+ GK+C+ D NEC S+ C++ C N Y+CSC GF +CQ++ + C C DF + C C TGW G+ C +DIDEC+ N K C N+ G Y C C +G +C D C S+PC+NG CV+ C C G++GD C++D++EC K+G G C + +Y C C PG+ D C + D + C NG C D C CP GF G C +++EC + PC G C + G+++C C Y
Sbjct: 112 CICPFGWRGNDCKFID--ACASQP---CANGSTCIPNENQYTCSCQAGYTGLKCEVDVNECGPPGMCKNGGTCENLPGSYRCQCHPGYTGQRCESPFIPCSPSPCMNGGTCRQT----SEFAYECNCLPGFDGKNCETNIDDCPSHKCQNGGTCVDGVNTYNCRCPPQWTGQFCTEDVDECQLQPNACQNGGTCTNSNGGYNCVCVNGWSGDDCSQNIDDCATAACANGSTCIDRVASFICVCPEGKIGLLCHKNDACFSNPCHMGSLCDTNPLTGQAICTCPSGYKGTACTEDIDECSLGDNPCEHAGKCVNTEGSFYCECSKGFTGPRCEMDINECLSEPCQNDATCLDKIGGFTCLCMPGYKGIHCEIEINECLSNPCVNNGECVDKVNRFVCICPPGFTGSVCQIDIDDCSSTPCQNGAKCVDHPSGYDCICATGFTGVLCEENINNCEPPPCHYGTCQDGIDSYTCICEPGYMGAICSDQIDECLSNPCLNEGRCVDLVNGYQCNCLPGTSGPQCKDDIDECASNPCHNGGTCVNEQNRFRCICPEGFRQPSCFSQVDECVNNPCIHGNCTDDVNGYKCLCQPGWTGKKCEVDKNEC--LSNPCQNGGTCDNLVNGYRCSCKKGF----KGTNCQNILTPCSPEPCHNGGICQESEDFKSFSCLCATGWHGQRCTIDIDECITNPCKNYGRCQNTKGGYICHC-----FEGFNGVNCENNIDDCLSNPCQNGASCVDGINTFSCNCLAGFHGDKCQKDVDECASNPCKNG--GSCTDYVNSYTCKCQPGF----DGIHCD-NNIDECTDTSCFNGATCVDGINSFTCQCPQGFTGQFCLFEINECGSH-PCIN-GGTCVDGMGTYHCTCPVGY 960 HSP 2 Score: 211.46 bits (537), Expect = 4.661e-55 Identity = 262/857 (30.57%), Postives = 352/857 (41.07%), Query Frame = 1
Query: 826 KSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSRGQM--GNRTCEHI----------------------------CVNEG------ENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFT-------------------------------LLSNGKCAINCLNN-------------CNKNGDCLNGICYCFSGWHGEDCSLDIDECKY-NHGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDL---MPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLA--EDKRSCIPPNKKTCLDKDCVH-GQCFN----SKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN--------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNSK------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC 2985
K C C G+ GE C +C + C +L + CIC N+C + C S+ C NG TC Q C C G+ G +C++++N C M TCE++ C+N G E ++C C GF N + C +C GT V + NC+C W G+FC +DVDEC L P CQ C N+ G Y C C G++ + GK + C N C+ N IC C SG+ G C+ DIDEC ++ CEH CVN GSF C+C GFT +++ +C+S+ C + CL+ GG C C PGY G +CE +PC +N C + VC C PG+ D C C KCV + C C GF G+LCE +IN C C + I S+ C C+ G+ A D+ CL C++ G+C + +C C G G +C +DI+EC C+N + ++C C GF SC S C N C N KC C+ GWTG+ C+VD +ECL N + C N Y CSC F G +C CS PC NGG C S+ C C G++G C DI+EC K+ G C+NT G Y C C G+ + C+ + D + NP C NG C D C C GFHG C DVDEC PC K G C + S+ C+C +DG C
Sbjct: 68 KGVCTCAPGFGGENCKQPVANVCSLTQPCMNGGTCRLLTLEL-YDCICPFGWRGNDCKFIDACASQPCANGSTCIPNENQYTCSCQAGYTGLKCEVDVNECGPPGMCKNGGTCENLPGSYRCQCHPGYTGQRCESPFIPCSPSPCMNGGTCRQTSEFAYECNCLPGFDGKNCETNIDDCPSHKCQNGGTCVDGVNTYNCRCPPQWTGQFCTEDVDECQLQPNACQNGGTCTNSNGGYNCVCVNGWSGDDCSQNIDDCATAACANGSTCIDRVASFICVCPEGKIGLLCHKNDACFSNPCHMGSLCDTNPLTGQAICTCPSGYKGTACTEDIDECSLGDNPCEHAGKCVNTEGSFYCECSKGFTGPRCEMDINECLSEPCQNDATCLDKIGGF----TCLCMPGYKGIHCEIEINECLSNPCVNNGECVDKVNRFVCICPPGFTGSVCQIDIDDCSSTPCQNGAKCVDHPSGYD-CICATGFTGVLCEENINNCEPPPCHYGTCQDGIDSYTCICEPGYMGAICSDQ-------IDECLSNPCLNEGRCVDLVNGYQCNCLPGTSGPQCKDDIDECASNPCHNGGTCVNEQNRFRCICPEGF----RQPSCFSQVDECVNNPCIHGNCTDDVNGYKCLCQPGWTGKKCEVDKNECLSNPCQNGGTCDNLVNGYRCSCKKGF-----KGTNCQNILTPCSPEPCHNGGICQESEDFKSFSCLCATGWHGQRCTIDIDECITNPCKN--YGRCQNTKGGYICHCFEGF----NGVNCENNIDDCLSNP-CQNGASCVDGINTFSCNCLAGFHGDKCQKDVDECAS-NPC-KNGGSCTDYVNSYTCKCQPG----FDGIHC 889 HSP 3 Score: 172.94 bits (437), Expect = 6.487e-43 Identity = 198/672 (29.46%), Postives = 283/672 (42.11%), Query Frame = 1
Query: 1054 RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG------------ICYCFSGWHGEDCSLDIDECKYNHGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCN--IECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-----------LSANSHSCQSVCSLCKNG----KCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCN--------------LPFYLSTVDGRSCLEKNDSCSSP-----CKNGGKCVNS----KCKCKPGYNGDSCEEDINEC-QWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDC 2853
+C C G G QC+ +I+ C+ N CVNE +N F+C C GF+ + C+ C T+ V+G C C+ GW GK C D +ECL CQ C N + Y+CSC++GF G N L C+ C NG C C +GWHG+ C++DIDEC N C++ C N G + C C GF + N C+S C C++G + C C G+ G C+ + +PC++ +CT ++ C C PG+D + + C C CV G N C+CP+GF G C +INEC GS C N TC+D + C C GYRGK C+E ++ C + C + KC C G+ A S +V LC++ F+++C+C+ G+ G C+ ++DEC N + CV+ +G Y C N LP Y V+ C E D C+ C NGG+C++ C+C PG+ G+ CE D+NEC P S G + +C NY C C PG+ + TC +C+ + RCYCP G G C
Sbjct: 610 QCNCLPGTSGPQCKDDIDECASNPCHNGG---TCVNE-QNRFRCICPEGFRQPSCFSQVDECVNNPCIHGNCTDDVNGYKCLCQPGWTGKKCEVDKNECLSNPCQNGGTCDNLVNGYRCSCKKGF----KGTNCQNILTPCSPE-PCHNGGICQESEDFKSFSCLCATGWHGQRCTIDIDECITNP-CKNYGRCQNTKGGYICHCFEGFNGVNCENNIDDCLSNPCQNGASCVDG--INTFSCNCLAGFHGDKCQKDVDECASNPCKNGGSCTDYVNSYTCKCQPGFDGIHCDNNIDECTDTSCFNGATCVDGI-NSFTCQCPQGFTGQFCLFEINEC--------------GSHPCI-----------------NGGTCVDGMGTY------HCTCPVGYRGKNCEELVDLCSGFPCKNRGICKQVKTEPKCICPTGWTGIYCDIPDVSCEVAASQRGVAVQDLCQHAGICINTGFSHRCQCRQGYIGSYCEGELDECASNPCQNSATCVDRHGGYECKVNSYNLSSLWNHNGICLPGY-QGVNCPLCEENIDDCAPSSEGPHCFNGGRCLDKIGGYSCECLPGFAGERCEGDVNECLSNPCSAKGSL-DCIQLDNNYLCKCKPGFTGKESNNTC--GHYKCKVGENCIKTPL---GPRCYCPTGPAGNAC 1224 HSP 4 Score: 136.346 bits (342), Expect = 1.109e-31 Identity = 152/541 (28.10%), Postives = 231/541 (42.70%), Query Frame = 1
Query: 1576 VNVPGSFNCQCHSGFTLQINKKKCISKSCNIE-------CLNGGLC------DKDKCKCPPGYIGHNCE--FNDFCHFISPCEH--NCTTINDNMV-CSCLPGYDLMPDKKTCKKLECPKCVRGTC---NENK--CKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLD-KDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMP---GFILSANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSC----------------NLPFYLSTV------------------DGRSCLEKNDSCS---SPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
N GS C+C F + K C ++ CLNGG C K C C PG+ G NC+ + C PC + C + + C C G+ D K C G+ NEN+ C C G+ GL CE D+NEC +C++ C N GS+ C+C G+ + IP + C++ C F +C C G+ GK C+ +I++C SH C++ C++ +Y C C P G + + CQ + C+NG N+ C C GW+G+ C +ID+C C++ S+ C C + P ++ ++ G +C E D CS +PC++ GKCVN++ C+C G+ G CE DINEC ++ C + G + C+C PGY + C+I + + NP C+N G C D C CP GF G C +D+D+C PC C + + C C++ +
Sbjct: 24 TNDDGSAYCKCTDAF---------VGKYCQLQNPCQETICLNGGTCKVSSDLSKGVCTCAPGFGGENCKQPVANVCSLTQPCMNGGTCRLLTLELYDCICPFGWRGN-DCKFIDACASQPCANGSTCIPNENQYTCSCQAGYTGLKCEVDVNECGPPGMCKNGGTCENLPGSYRCQCHPGYTGQRCESPFIPCSPSPCMNGGTCRQTSEFAYECNCLPGFDGKNCETNIDDCP--SHKCQNGGTCVDGVNTYNCRCPPQWTGQFCTEDVDECQLQPNACQNGGTCTNSNGGYNCVCVNGWSGDDCSQNIDDCATAACANGSTCIDRVASFICVCPEGKIGLLCHKNDACFSNPCHMGSLCDTNPLTGQAICTCPSGYKGTACTEDIDECSLGDNPCEHAGKCVNTEGSFYCECSKGFTGPRCEMDINECLSEPCQND--ATCLDKIGGFTCLCMPGYKGIH----CEIEINECLSNP-CVNNGECVDKVNRFVCICPPGFTGSVCQIDIDDCSS-TPCQN-GAKCVDHPSGYDCICATGFT 543 HSP 5 Score: 79.7221 bits (195), Expect = 2.846e-14 Identity = 136/537 (25.33%), Postives = 191/537 (35.57%), Query Frame = 1
Query: 790 CVPD-CGEHGICVKSR------CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLE-LRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGF------------------------TLLSNGKC-------------------------AINCLNNCNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQC----------HSGFTL-----------QINKKKCISKSCNIECLNGGLC-DKD---KCKCPPGYIGHNCEFNDFCHFISPCEH----NCTTINDNMVCSCLPGYDLMPDKKTCKKLEC------------PKCV-----------------------RGTCNEN------KCKCPKGFAGLLCE 1950
C P+ C GIC +S C C TGW G+RC I E C + K + C C NC + C S CQNG +C G C C GF GD+CQ +++ C+ + C N G N++ CKCQ GF DN+ C C T + S C+C QG+ G+FC +++EC C CV+ +G+Y C+C G+ + + KC + + C G C+N C C G+ G C ++DEC N C++ CV+ G + C+ H+G L + N C S C NGG C DK C+C PG+ G CE + +PC +C +++N +C C PG+ TC +C P+C G C C CP G GL CE
Sbjct: 742 CSPEPCHNGGICQESEDFKSFSCLCATGWHGQRCTIDIDECITNP----CKNYGRCQNTKGGYICHCFEGFNGVNCENNIDDCLSNPCQNGASCVDGINTFSCNCLAGFHGDKCQKDVDECA---------SNPCKNGGSCTDYVNSYTCKCQPGFDGIHCDNNIDECTDTSCFNGATCVDGINSFTCQCPQGFTGQFCLFEINECGSHPCINGGTCVDGMGTYHCTCPVGYRGKNCEELVDLCSGFPCKNRGICKQVKTEPKCICPTGWTGIYCDIPDVSCEVAASQRGVAVQDLCQHAGICINTGFSHRCQCRQGYIGSYCEGELDECASNP-CQNSATCVDRHGGYECKVNSYNLSSLWNHNGICLPGYQGVNCPLCEENIDDCAPSSEGPHCFNGGRCLDKIGGYSCECLPGFAGERCEGDVNECLSNPCSAKGSLDCIQLDNNYLCKCKPGFTGKESNNTCGHYKCKVGENCIKTPLGPRCYCPTGPAGNACQSKLGCTSQPCKNNGVCQRKDQPPYYTCNCPNGIVGLQCE 1264
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 216.083 bits (549), Expect = 1.574e-56 Identity = 223/727 (30.67%), Postives = 318/727 (43.74%), Query Frame = 1
Query: 1000 ELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQ-MGNRTCEHICVNEGENNFQCKCQSGF-----QLDNDGKSCIKEECSKFGT--TEVVSGN--CKCKQGWKGKFCNDDVDECLFPV--CQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVR------GTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
E + CQNGGTC C C G+ G+ C I+ C+ TC + F C+C G LDN +CI C++ T V+G C C G+ G CN+DVDEC C+ C NT+GS+QC+C +G+ + +C I+ CL+N C + CL+ I C C G+ G C DI+EC + C + +F C C G+T ++ + +C+S+ C NGG C + C CP G G NCE N +PC++ C D C+C PGY K C + +C GTC + C CP G+ +C +++NEC + C + I + C C G + + C+ N TC D + C C++G+ G C +INEC + C++ YKC+CM L C++V + C C +CK C GW G+ C++D++EC+ + C N+NGSY C+C P Y GR C D C +PC NGG C + C C G+ G CEEDINEC K+G C + +Y C C PG+ + C+ +T D C NGG C D C CP GF G C D++EC PC G C ++YG++ C C Y +
Sbjct: 297 ECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVAS-----FFCECPHGRTGLLCHLDN---ACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQGY---AGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPGFTGRHCEQDINECIPDPCHYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSQPCQ----NGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYT----GKMCN-INIDECASNPCRNGGTCKDKINGFTCVCPDGYHDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCM--NGGTCKDMTGAY------ICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCM----LPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCK-PGYA----GRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNG--ANCTDCVNSYTCTCQPGFSGIH----CENNTPDCT-ESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDS-KPCLN-GGTCQDSYGAYKCTCPQGYTGL 977 HSP 2 Score: 204.142 bits (518), Expect = 9.831e-53 Identity = 236/804 (29.35%), Postives = 342/804 (42.54%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRT---CSKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEG-----ENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVN-------TIGSYQCSCREGFTLLSNGKCAINCL-NNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK-YNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEH--NCTT--INDNMVCSCLPGYDLMP---DKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCK---NGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHF--CMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN--------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI-GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCY---CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKP 3015
C C + +FGERC P K + + F +DF+C C + T CL + C+NGGTC RC+C G+ GD CQ + + C+ + C N G E + CKC SGF D C + C G E S C C+ + G+ C +E P C+N SY+C+C GF+ + + +C NNC G C++G+ C C W G+ C+ D+DEC+ + C++ C N G +NC C +G+T + + + I N C +G C C+CP G G C ++ C +PC NC T +N +C+C PGY D C L C G T +C CP+G+AG CE D+NECL+ CQ+ C + IG F C C G +D CIP C +G C + C+C+ GY G+ CD DINEC S C++ C + E Y C+C G +C++ C + CD+ +C C+ G+TG++C+++IDEC S+PC+NGG C + C C GY+ C ++NEC + + CI G C + Y+C C G+ C ++ + NP C+NGG C+DM+ Y C GF G +C +++EC PC RG C + + C C +L Y G C EAVL P
Sbjct: 45 CLCSSSYFGERCQYPNPCALKNQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQ-QADPCA---------SNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGSYRCNCQNRFTGRNC----EEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGE-DCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNAC-ISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDEC-SLGANPCEHGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNP-CQNDATCLDQIGEFQCICMPGFTGRHCEQDINECIP--------DPCHYGTCKDGIATFTCLCRPGYTGRLCDNDINEC--LSQPCQNGGQCTDRENGYICTCPKG----TTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECA------------------------------------------SNPCRNGGTCKDKINGFTCVCPDGYHDHMCLSEVNEC----NSNPCIHGTCHDGINGYKCDCDAGW----SGSNCDVNNNECESNP-CMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECAS-NPCLN-RGTCIDDVAGYKCNC----MLPYTGAIC----EAVLAP 755 HSP 3 Score: 173.326 bits (438), Expect = 5.036e-43 Identity = 216/738 (29.27%), Postives = 309/738 (41.87%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTC--FQGR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH-------NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQHV-----------CTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQSVC-SLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCR-----DMSRCYCPIGFHGIDCGV 2859
C+HG D + C C + +NC + C S C NGGTC G C C GF G CQ IN C+ NR C+++ ++C C +G + C C G + + + +C+C GW+G+ C D++EC+ C+ +C NT GSY+C+C+ G+ +C N C+ G C +GI C C +G+ G C DI+EC N +G C + S+ C C GF+ + N C SC NGG C + C+CPPG+ G+ C+ H I+ C+ C C+C GY + + + + C G T N +C+C G+ G+ C+ C Q V C +T + FCRC+ G+ + E C P N TC D C C +GY G C E+INEC SH C + C++ +YKCSC G N C S+ KC FNN C C G+ GE C+ D++ECL N + NC+ Y C C F GR C D C PC+NGG C + CKC PG++G +CE D C ++G G C + + +C+C GY TCQ + C NGG C+ +C+CP F+G+ C +
Sbjct: 648 CIHGTCHDGIN-GYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRG---TCIDDVAG-YKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGAN--CTDCVNSYTCTCQPGFSGIHCENNTPDCTESSC----FNGGTCIDGINTFSCQCPPGFTGNYCQ-----HDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTD------YLGGYSCECVAGYHGVNCSEEINEC--LSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKC-FNNGKCIDRVGGYNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFT-----GRRCDSVVDGCKGLPCRNGGTCAVASNTERGFICKCPPGFDGATCEYDARTCGNLRCQNG--GTCISVLKSSKCVCSEGYT----GATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCPTNFNGLFCHI 1349 HSP 4 Score: 167.548 bits (423), Expect = 2.567e-41 Identity = 203/735 (27.62%), Postives = 303/735 (41.22%), Query Frame = 1
Query: 1015 SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-------DCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQ--------SVCSLCKN-GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCI-------GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP-------HCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLR--GICYNTYGSFYCQCSSNY---VLMYDGTSCMTMK 2997
S C+NGGTC C C +G+ C E+N C+ + C H ++G N ++C C +G+ N + C C GT + ++G C C+ G+ G C +++EC C + C++ + Y+C+C +T C + KNG D C C GW G+ C +D++EC N C + +C N GS+ C C G+ + + C C+ NGG C C CP G+ G CE + +PC++ NCT ++ C+C PG+ + PD C+ G N C+CP GF G C++DINEC D + C+ N TC D + KC C GY G C + C C T Y+C C G+ S SC+ + LC+N G C D N C+C+ G+TG C+ +DEC N + C + G YSC C ++ G +C E+ + C S PC NGG C++ KC C G G CE ++++C P + G+C + G Y CICPPG++ + C+ + + NP +C+ + D RC C GF G C VD C+ PC + NT F C+C + YD +C ++
Sbjct: 607 SNPCRNGGTCKDKINGFTCVCPDGYHDHMCLSEVNECN-----SNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNEC-VNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCH----NGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGI-NTFSCQCPPGFTGNYCQHDINEC-----------------------------DSKPCL--NGGTCQDSYGAY------KCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCEC-----VAGYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCT-PFYDSVSLEPKCFNNGKCIDRVGGYNCICPPGFV----GERCEGDVNECLSNPCDPRGTQNCIQ--LVNDY-RCECRQGFTGRRCDSVVDGCKGL-PCRNGGTCAVASNTERGFICKCPPGFDGATCEYDARTCGNLR 1279 HSP 5 Score: 153.295 bits (386), Expect = 7.022e-37 Identity = 156/525 (29.71%), Postives = 221/525 (42.10%), Query Frame = 1
Query: 1483 GICYCFSGWHGEDCSLD-----IDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCD------KDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLD-KDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMP---GFILSANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC----VNSK--CKCKPGYNGDSCEEDINECQWPIS--KHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
G+C C S + GE C ++C CE + + F C C GFT ++ + N C NGG C+ +C+CPPG+ G +C+ D PC N C G +P + + CKCP GF G C+ DINEC +Q C++ C N GS+ C C+N + +P N CL+ C + +C C G+ G+ C+E+I++C + C++ +Y C C P G + + CQ + + C+NG N C C GWTGE C +ID+C C + S+ C C G C N S+PC G C VN K C C PGY G +C D++EC + +HG G C NT G+++C CP GY C+I + + NP C N C D +C C GF G C D++EC PC G C + +F C C Y
Sbjct: 43 GVCLCSSSYFGERCQYPNPCALKNQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQAD------PCASN----------PCANGGKCLPFET----------------QYICKCPSGFHGATCKQDINEC-SQNPCRNGGQCLNEFGSYRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCEC-----PHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHG--GRCTNTLGSFQCNCPQGYA----GPRCEIDVNECLSNP-CQNDATCLDQIGEFQCICMPGFTGRHCEQDINECIP-DPCH--YGTCKDGIATFTCLCRPGYT 519
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 211.46 bits (537), Expect = 5.277e-55 Identity = 240/819 (29.30%), Postives = 346/819 (42.25%), Query Frame = 1
Query: 841 CETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRT---CSKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEG-----ENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIG-SYQCSCREGFTLLSNGKCAINCL-NNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK-YNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEH--NCTT--INDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVH-GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSV---------CSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGY---LVLDD------------------------------QKTCQISTKDTMCNPHCLNGGVCRDMSRCY---CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKP 3015
C + +FGERC P K + + F +DF+C C + T CL + C+NGGTC RC+C G+ GD CQ + + C+ + C N G E + CKC SGF D C + C G E S C C+ + G+ C + C C C T SY+C+C GF+ + + +C NNC G C++G+ C C W G+ C+ D+DEC+ + C++ C N G +NC C +G+T + + + I N C +G C C+CP G G C ++ C +PC NC T +N +C+C PGY + KC T +C CP+G+AG CE D+NECL+ CQ+ C + IG F C C G A N C C+H G+C + C C +G+ G C D++EC C++ SY C C GF H Q + CK+G F C C+ G+TG LCD DI+ECL + C + Y C+C G +C D C+S + GKC++ +C C+PGY G C +I+EC ++G G C++ + C+CP GY + L + C ++ + NP C+NGG C+DM+ Y C GF G +C +++EC PC RG C + + C C +L Y G C EAVL P
Sbjct: 6 CSSSYFGERCQYPNPCALKNQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQ-QADPCA---------SNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGSYRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGE-DCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNAC-ISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGKCTN-TLGSFQCNCPQGYAGPRCEIDVNECLSNP-CQNDATCLDQIGEFQCICMPGVLSAT--------NIDECASNPCLHNGKCVDKINEFHCECPTGFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGF---TGRHCEQDINECIPDPCHYGTCKDGIATF--TCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENGYICTC-----PKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNPCRNG--GTCKDKINGFTCVCPDGYHDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNP-CMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECAS-NPCLN-RGTCIDDVAGYKCNC----MLPYTGAIC----EAVLAP 779 HSP 2 Score: 202.986 bits (515), Expect = 2.583e-52 Identity = 246/837 (29.39%), Postives = 349/837 (41.70%), Query Frame = 1
Query: 781 IDNCVPD-CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLL--FCVHGCSFDKRKLDFSCICGIKETQNNCLE-LRTCS-KGCQNGGTCFQGR----CQCTEGFEGDQCQLE----INSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSN-GKCAINCLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNI----------------------------ECL-----NGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVR------GTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
ID+C + C G CV C C W G+ C E + +L+ C +G + ++C+C T +C E + C+ C +G TC C+C G G C L+ N C+ G C+ VN C C G+ +ND C +C T + S C C QG+ G C DV+ECL CQ C++ IG +QC C G +N +CA N C NG C++ I C C +G++G C D+DEC +G + C++ P S+ CQC GFT + + +CI C+ ECL NGG C + C CP G G NCE N +PC++ C D C+C PGY K C + +C GTC + C CP G+ +C +++NEC + C + I + C C G + + C+ N TC D + C C++G+ G C +INEC + C++ YKC+CM L C++V + C C +CK C GW G+ C++D++EC+ + C N+NGSY C+C P Y GR C D C +PC NGG C + C C G+ G CEEDINEC K+G C + +Y C C PG+ + C+ +T D C NGG C D C CP GF G C D++EC PC G C ++YG++ C C Y +
Sbjct: 216 IDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCT----EDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNACISNPCNEGS----NCDTNPVN---GKAICTCPPGYTGPACNNDVDECSLGKC----TNTLGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPGVLSATNIDECASN---PCLHNGKCVDKINEFHCECPTGFNGNLCQHDVDECASTPCKNGAK--CLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYT----GKMCN-INIDECASNPCRNGGTCKDKINGFTCVCPDGYHDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCM--NGGTCKDMTGAY------ICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCM----LPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCK-PGYA----GRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNG--ANCTDCVNSYTCTCQPGFSGIH----CENNTPDCT-ESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDS-KPCLN-GGTCQDSYGAYKCTCPQGYTGL 1001 HSP 3 Score: 173.711 bits (439), Expect = 3.613e-43 Identity = 216/738 (29.27%), Postives = 309/738 (41.87%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTC--FQGR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH-------NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQHV-----------CTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQSVC-SLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCR-----DMSRCYCPIGFHGIDCGV 2859
C+HG D + C C + +NC + C S C NGGTC G C C GF G CQ IN C+ NR C+++ ++C C +G + C C G + + + +C+C GW+G+ C D++EC+ C+ +C NT GSY+C+C+ G+ +C N C+ G C +GI C C +G+ G C DI+EC N +G C + S+ C C GF+ + N C SC NGG C + C+CPPG+ G+ C+ H I+ C+ C C+C GY + + + + C G T N +C+C G+ G+ C+ C Q V C +T + FCRC+ G+ + E C P N TC D C C +GY G C E+INEC SH C + C++ +YKCSC G N C S+ KC FNN C C G+ GE C+ D++ECL N + NC+ Y C C F GR C D C PC+NGG C + CKC PG++G +CE D C ++G G C + + +C+C GY TCQ + C NGG C+ +C+CP F+G+ C +
Sbjct: 672 CIHGTCHDGIN-GYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRG---TCIDDVAG-YKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGAN--CTDCVNSYTCTCQPGFSGIHCENNTPDCTESSC----FNGGTCIDGINTFSCQCPPGFTGNYCQ-----HDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTD------YLGGYSCECVAGYHGVNCSEEINEC--LSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKC-FNNGKCIDRVGGYNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFT-----GRRCDSVVDGCKGLPCRNGGTCAVASNTERGFICKCPPGFDGATCEYDARTCGNLRCQNG--GTCISVLKSSKCVCSEGYT----GATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCPTNFNGLFCHI 1373 HSP 4 Score: 171.4 bits (433), Expect = 1.969e-42 Identity = 227/858 (26.46%), Postives = 332/858 (38.69%), Query Frame = 1
Query: 1015 SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFG----------------TTEV----------------------VSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN----GDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH-LCVNVPGSFNCQCHSGFTL---QINKKKCISKSC----------------------------------NIECLNGGLCDKDK------CKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDLM---PDKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQHV-CTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-----------------------LSANSHSCQ--------------------------SVCSLCKN-GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCI-------GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP-------HCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLR--GICYNTYGSFYCQCSSNY---VLMYDGTSCMTMK 2997
S C+NG C G CQCTEGF G C+ +IN C TC+ +G F C C+ G+ DND C+ + C G TT V + G C C+ G+ GK CN ++DEC C+ C + I + C C +G+ + ++ +N CN N G C +GI C C +GW G +C ++ +EC+ N C ++ G++ C C +GF+ Q N +C S C C NGG C + + C+CPPG+ G CE + PC + C N + C+C PGY D C+ C G+C++ C CP GF G CE DINEC + CT+ + S+ C C+ G + + DC CFN C C G+ G C DINEC + C ++ G+YKC+C G+ + N + C+ + LC+N G C D N C+C+ G+TG C+ +DEC N + C + G YSC C ++ G +C E+ + C S PC NGG C++ KC C G G CE ++++C P + G+C + G Y CICPPG++ + C+ + + NP +C+ + D RC C GF G C VD C+ PC + NT F C+C + YD +C ++
Sbjct: 481 STPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTCK-----DGIATFTCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKINGFTCVCPDGY----HDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHN--GGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENN----------TPDCTESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCEC-----VAGYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCT-PFYDSVSLEPKCFNNGKCIDRVGGYNCICPPGFV----GERCEGDVNECLSNPCDPRGTQNCIQ--LVNDY-RCECRQGFTGRRCDSVVDGCKGL-PCRNGGTCAVASNTERGFICKCPPGFDGATCEYDARTCGNLR 1303 HSP 5 Score: 153.295 bits (386), Expect = 7.805e-37 Identity = 193/724 (26.66%), Postives = 304/724 (41.99%), Query Frame = 1
Query: 1015 SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-------DCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRC---------------------KNGHKLAEDKR--------------------SCIPPNKKTCLDKDCV---HGQCFNSK----CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKC--DFNN--KCKCKTGWTGELCDVDIDEC------LLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGG-----KCVNS-KCKCKPGYNGDSCEEDINECQ-WPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDV 2865
S C+NGGTC C C +G+ C E+N C+ + C H ++G N ++C C +G+ N + C C GT + ++G C C+ G+ G C +++EC C + C++ + Y+C+C +T C + KNG D C C GW G+ C +D++EC N C + +C N GS+ C C G+ + + C C+ NGG C C CP G+ G CE + +PC++ NCT ++ C+C PG+ + PD C+ G N C+CP GF G C++DINEC ++ + C ++ G++ C C KNG K + SC K+ +D + G C ++ C C++GY G C+E ++EC C + G Y C C+ G+ ++ + + + C NG D N KC C G G C++++D+C + + KC +N C++ G Y+C C F +G + N+ S+PC G + VN +C+C+ G+ G C+ ++ C+ P G NT + C CPPG+ D TC+ + T N C NGG C + S+C C G+ G C V
Sbjct: 631 SNPCRNGGTCKDKINGFTCVCPDGYHDHMCLSEVNECN-----SNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNEC-VNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCH----NGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGI-NTFSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVAGYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGGYNCICPPGFVGERCEG----DVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFTGRRCDSVVDGCKGLPCRNGGTCAVASNTERGFICKCPPGF----DGATCEYDAR-TCGNLRCQNGGTCISVLKSSKCVCSEGYTGATCQYPV 1334 HSP 6 Score: 115.161 bits (287), Expect = 4.046e-25 Identity = 133/488 (27.25%), Postives = 195/488 (39.96%), Query Frame = 1
Query: 1714 PPGYIGHNCEFNDFCHFISPCEHNCTTIN------------DNMVCSCLPGYD----LMP-----------DKKTCKKL--------ECPKCVRG-------TCNENKC---------------KCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLD-KDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMP---GFILSANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC----VNSK--CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
PP ++ + F + C + +PC +N + C C G+ L P + TC+ L CP G C N C KCP GF G C+ DINEC +Q C++ C N GS+ C C+N + +P N CL+ C + +C C G+ G+ C+E+I++C + C++ +Y C C P G + + CQ + + C+NG N C C GWTGE C +ID+C C + S+ C C G C N S+PC G C VN K C C PGY G +C D++EC +G+C NT G+++C CP GY C+I + + NP C N C D + I G+ ++DEC PC G C + F+C+C + +
Sbjct: 1 PPSFLCSSSYFGERCQYPNPCALKNQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADPCASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINEC-SQNPCRNGGQCLNEFGSYRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCEC-----PHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECS--------LGKCTNTLGSFQCNCPQGYA----GPRCEIDVNECLSNP-CQNDATCLDQIGEFQCICMPGVLSATNIDECAS-NPC-LHNGKCVDKINEFHCECPTGF 467
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 211.46 bits (537), Expect = 5.464e-55 Identity = 233/787 (29.61%), Postives = 329/787 (41.80%), Query Frame = 1
Query: 835 CYCETGWFGERC----------VILEPELCKQRKLLF---CVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCN----KNG-DCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVR------GTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
C C GW GE C C R F C HG + LD +CI N C E C NG + C C G+ G C +++ CS +G CEH C N +FQC C G+ + + D C+ C T ++ C C G++G +C ++DEC C CV+ I + C C GF NG + ++ C KNG CL+G C C G+ G C DI+EC + C + +F C C G+T ++ + +C+S+ C NGG C + C CP G G NCE N +PC++ C D C+C PGY K C + +C GTC + C CP G+ +C +++NEC + C + I + C C G + + C+ N TC D + C C++G+ G C +INEC + C++ YKC+CM L C++V + C C +CK C GW G+ C++D++EC+ + C N+NGSY C+C P Y GR C D C +PC NGG C + C C G+ G CEEDINEC K+G C + +Y C C PG+ + C+ +T D C NGG C D C CP GF G C D++EC PC G C ++YG++ C C Y +
Sbjct: 284 CVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNACI------SNPCNEGSNCDTNPVNG----KAICTCPPGYTGPACNNDVDECS---LGANPCEHGGRCTNT-LGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPGYEGLYCETNIDECASNPCLHNGKCVDKINEFHCECPTGF----NGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSQPCQ----NGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYT----GKMCN-INIDECASNPCRNGGTCKDKINGFTCVCPDGYHDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCM--NGGTCKDMTGAY------ICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCM----LPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCK-PGYA----GRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNG--ANCTDCVNSYTCTCQPGFSGIH----CENNTPDCT-ESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDS-KPCLN-GGTCQDSYGAYKCTCPQGYTGL 1017 HSP 2 Score: 209.534 bits (532), Expect = 2.205e-54 Identity = 243/829 (29.31%), Postives = 351/829 (42.34%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRT---CSKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEG-----ENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIG-SYQCSCREGFTLLSNGKCAINCL-NNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK-YNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEH--NCTT--INDNMVCSCLPGYDLMP---DKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVH-GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSV---------CSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGY---LVLDD------------------------------QKTCQISTKDTMCNPHCLNGGVCRDMSRCY---CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKP 3015
C C + +FGERC P K + + F +DF+C C + T CL + C+NGGTC RC+C G+ GD CQ + + C+ + C N G E + CKC SGF D C + C G E S C C+ + G+ C + C C C T SY+C+C GF+ + + +C NNC G C++G+ C C W G+ C+ D+DEC+ + C++ C N G +NC C +G+T + + + I N C +G C C+CP G G C ++ C +PC NC T +N +C+C PGY D C L C G T +C CP+G+AG CE D+NECL+ CQ+ C + IG F C C G++ + N C C+H G+C + C C +G+ G C D++EC C++ SY C C GF H Q + CK+G F C C+ G+TG LCD DI+ECL + C + Y C+C G +C D C+S + GKC++ +C C+PGY G C +I+EC ++G G C++ + C+CP GY + L + C ++ + NP C+NGG C+DM+ Y C GF G +C +++EC PC RG C + + C C +L Y G C EAVL P
Sbjct: 9 CLCSSSYFGERCQYPNPCALKNQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQ-QADPCA---------SNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGSYRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGE-DCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNAC-ISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDEC-SLGANPCEHGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNP-CQNDATCLDQIGEFQCICMPGYEGLYCET-----NIDECASNPCLHNGKCVDKINEFHCECPTGFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGF---TGRHCEQDINECIPDPCHYGTCKDGIATF--TCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENGYICTC-----PKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNPCRNG--GTCKDKINGFTCVCPDGYHDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNP-CMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECAS-NPCLN-RGTCIDDVAGYKCNC----MLPYTGAIC----EAVLAP 795 HSP 3 Score: 203.756 bits (517), Expect = 1.450e-52 Identity = 255/916 (27.84%), Postives = 355/916 (38.76%), Query Frame = 1
Query: 814 GICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHG--CSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCS---------------------RGQMGNRTCEH--------ICVNEG------ENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLLS-------------------------------NGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDL---MPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKL-----------------------AEDKRSCIPPNKKT----------CLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN--------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFY---------------------------------LSTVDGRSCLEKNDSCS-SPCKNGGKCVNSK------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
G + C+C G+ + C+ C C +G C D+ C C T ++C + C S C NGG C Q C+C GF G C+ +IN CS + + R CE C+N G + +++C C GF N + C C GT V + NC+C W G++C +DVDEC L P CQ C NT G Y C C G+T +G+ + C N CN+ +C +NG IC C G+ G C+ D+DEC + CEH C N GSF C C G+ +I+ +C+S C + + +C C PGY G CE N +PC HN C + C C G++ D C C KC+ G N C+C +GF G CE DINEC+ C + I +F C C+ G+ E+ C P T C C +G+C + +C C+ GY GK C+ +I+EC C + + C C G+ + H C S + C + C KC C GW+G CDV+ +EC N C + G+Y C+C F + G C CS SPCKNGG+C S+ C+C PG+ G +CE D+NEC ++G + C+NT G+Y+C C PGY + C+ D NP C NGG C D M C CP GF G C D++EC PC K C + S+ C C + ++
Sbjct: 44 GNAIDFTCHCPVGFTDKVCLTPVDNACVNNP---CRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADPCASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGSYRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPGYEGLYCETNIDECASNPCLHNGKCVDKINEFHCECPTGFNGNLCQHDVDECASTPCKNGAKCLDGP-NSYTCQCTEGFTGRHCEQDINECIPDPCHYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKINGFTCVCPDGY----HDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAM--CQNTNGSYKCNCKPGYA----GRHCETDIDDCQPNP-CHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECAS-NPC-KNGANCTDCVNSYTCTCQPGFSGIH 942 HSP 4 Score: 173.711 bits (439), Expect = 3.229e-43 Identity = 216/738 (29.27%), Postives = 309/738 (41.87%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTC--FQGR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH-------NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQHV-----------CTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQSVC-SLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCR-----DMSRCYCPIGFHGIDCGV 2859
C+HG D + C C + +NC + C S C NGGTC G C C GF G CQ IN C+ NR C+++ ++C C +G + C C G + + + +C+C GW+G+ C D++EC+ C+ +C NT GSY+C+C+ G+ +C N C+ G C +GI C C +G+ G C DI+EC N +G C + S+ C C GF+ + N C SC NGG C + C+CPPG+ G+ C+ H I+ C+ C C+C GY + + + + C G T N +C+C G+ G+ C+ C Q V C +T + FCRC+ G+ + E C P N TC D C C +GY G C E+INEC SH C + C++ +YKCSC G N C S+ KC FNN C C G+ GE C+ D++ECL N + NC+ Y C C F GR C D C PC+NGG C + CKC PG++G +CE D C ++G G C + + +C+C GY TCQ + C NGG C+ +C+CP F+G+ C +
Sbjct: 688 CIHGTCHDGIN-GYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRG---TCIDDVAG-YKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGAN--CTDCVNSYTCTCQPGFSGIHCENNTPDCTESSC----FNGGTCIDGINTFSCQCPPGFTGNYCQ-----HDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTD------YLGGYSCECVAGYHGVNCSEEINEC--LSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKC-FNNGKCIDRVGGYNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFT-----GRRCDSVVDGCKGLPCRNGGTCAVASNTERGFICKCPPGFDGATCEYDARTCGNLRCQNG--GTCISVLKSSKCVCSEGYT----GATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCPTNFNGLFCHI 1389 HSP 5 Score: 171.4 bits (433), Expect = 1.776e-42 Identity = 227/858 (26.46%), Postives = 332/858 (38.69%), Query Frame = 1
Query: 1015 SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFG----------------TTEV----------------------VSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN----GDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH-LCVNVPGSFNCQCHSGFTL---QINKKKCISKSC----------------------------------NIECLNGGLCDKDK------CKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDLM---PDKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQHV-CTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-----------------------LSANSHSCQ--------------------------SVCSLCKN-GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCI-------GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP-------HCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLR--GICYNTYGSFYCQCSSNY---VLMYDGTSCMTMK 2997
S C+NG C G CQCTEGF G C+ +IN C TC+ +G F C C+ G+ DND C+ + C G TT V + G C C+ G+ GK CN ++DEC C+ C + I + C C +G+ + ++ +N CN N G C +GI C C +GW G +C ++ +EC+ N C ++ G++ C C +GF+ Q N +C S C C NGG C + + C+CPPG+ G CE + PC + C N + C+C PGY D C+ C G+C++ C CP GF G CE DINEC + CT+ + S+ C C+ G + + DC CFN C C G+ G C DINEC + C ++ G+YKC+C G+ + N + C+ + LC+N G C D N C+C+ G+TG C+ +DEC N + C + G YSC C ++ G +C E+ + C S PC NGG C++ KC C G G CE ++++C P + G+C + G Y CICPPG++ + C+ + + NP +C+ + D RC C GF G C VD C+ PC + NT F C+C + YD +C ++
Sbjct: 497 STPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTCK-----DGIATFTCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKINGFTCVCPDGY----HDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHN--GGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENN----------TPDCTESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCEC-----VAGYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCT-PFYDSVSLEPKCFNNGKCIDRVGGYNCICPPGFV----GERCEGDVNECLSNPCDPRGTQNCIQ--LVNDY-RCECRQGFTGRRCDSVVDGCKGL-PCRNGGTCAVASNTERGFICKCPPGFDGATCEYDARTCGNLR 1319 HSP 6 Score: 155.992 bits (393), Expect = 1.100e-37 Identity = 154/524 (29.39%), Postives = 224/524 (42.75%), Query Frame = 1
Query: 1483 GICYCFSGWHGEDCSLD-----IDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCD------KDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLD-KDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMP---GFILSANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC----VNSK--CKCKPGYNGDSCEEDINECQWPIS--KHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
G+C C S + GE C ++C CE + + F C C GFT ++ + N C NGG C+ +C+CPPG+ G +C+ D PC N C G +P + + CKCP GF G C+ DINEC +Q C++ C N GS+ C C+N + +P N CL+ C + +C C G+ G+ C+E+I++C + C++ +Y C C P G + + CQ + + C+NG N C C GWTGE C +ID+C C + S+ C C G C N S+PC G C VN K C C PGY G +C D++EC + +HG G C NT G+++C CP GY C+I + + NP C N C D +C C G+ G+ C ++DEC PC G C + F+C+C + +
Sbjct: 7 GVCLCSSSYFGERCQYPNPCALKNQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQAD------PCASN----------PCANGGKCLPFET----------------QYICKCPSGFHGATCKQDINEC-SQNPCRNGGQCLNEFGSYRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCEC-----PHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHG--GRCTNTLGSFQCNCPQGYA----GPRCEIDVNECLSNP-CQNDATCLDQIGEFQCICMPGYEGLYCETNIDECAS-NPC-LHNGKCVDKINEFHCECPTGF 483 HSP 7 Score: 153.295 bits (386), Expect = 6.982e-37 Identity = 193/724 (26.66%), Postives = 304/724 (41.99%), Query Frame = 1
Query: 1015 SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-------DCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRC---------------------KNGHKLAEDKR--------------------SCIPPNKKTCLDKDCV---HGQCFNSK----CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKC--DFNN--KCKCKTGWTGELCDVDIDEC------LLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGG-----KCVNS-KCKCKPGYNGDSCEEDINECQ-WPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDV 2865
S C+NGGTC C C +G+ C E+N C+ + C H ++G N ++C C +G+ N + C C GT + ++G C C+ G+ G C +++EC C + C++ + Y+C+C +T C + KNG D C C GW G+ C +D++EC N C + +C N GS+ C C G+ + + C C+ NGG C C CP G+ G CE + +PC++ NCT ++ C+C PG+ + PD C+ G N C+CP GF G C++DINEC ++ + C ++ G++ C C KNG K + SC K+ +D + G C ++ C C++GY G C+E ++EC C + G Y C C+ G+ ++ + + + C NG D N KC C G G C++++D+C + + KC +N C++ G Y+C C F +G + N+ S+PC G + VN +C+C+ G+ G C+ ++ C+ P G NT + C CPPG+ D TC+ + T N C NGG C + S+C C G+ G C V
Sbjct: 647 SNPCRNGGTCKDKINGFTCVCPDGYHDHMCLSEVNECN-----SNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNEC-VNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCH----NGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGI-NTFSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVAGYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGGYNCICPPGFVGERCEG----DVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFTGRRCDSVVDGCKGLPCRNGGTCAVASNTERGFICKCPPGF----DGATCEYDAR-TCGNLRCQNGGTCISVLKSSKCVCSEGYTGATCQYPV 1350
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Notch1 (notch 1 [Source:MGI Symbol;Acc:MGI:97363]) HSP 1 Score: 213.772 bits (543), Expect = 7.427e-56 Identity = 231/772 (29.92%), Postives = 327/772 (42.36%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-DCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC-DKDK---CKCPPGYIGHNCEFNDFCHFISPCEH-NCTTINDNMVCSCLPGYD-LMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
C C GW GE C E C G + R F C C T C C S C G C + C C G+ G C +++ C+ +G CEH C+N +F+C+C G+ + + D CI C T ++ C C G++G +C + DEC C C++ I +QC C +GF C + KNG CL+G C C G+ G C +DIDEC + C + +F C C G+T + N +C S+ C +GG C D+D C C G G NCE N +PC+ C D C+C PGY M + + P GTC + C+CP+G+ C +++NEC + C + + + C C G + C+ N TC KD G C C+ G+ G C +INEC + + C++ YKC+C L +C+ V + C C + CK C TGW G+ C+VDI+EC+ + + +C N+NGSY C C + GR+C D C +PC NGG C + + C C PG+ G CEEDINEC ++G C + +Y C CP G+ + C+ +T D C NGG C D C CP GF G C DV+EC PC G C ++YG++ C C Y +
Sbjct: 321 CVCVNGWTGEDCS----ENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECA---LGANPCEHAGKCLNT-LGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGHCMDKINEFQCQCPKGFNGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCQPGYTGHHCETNINECHSQPCR----HGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCV--NGGTC--KDMTSGYV----CTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCP----LPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGASCQNTNGSYRCLCQAGYT-----GRNCESDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNPCQNG--ANCTDCVDSYTCTCPVGFNGIH----CENNTPDCT-ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSR-PCLH-GGTCQDSYGTYKCTCPQGYTGL 1054 HSP 2 Score: 196.438 bits (498), Expect = 2.162e-50 Identity = 243/883 (27.52%), Postives = 355/883 (40.20%), Query Frame = 1
Query: 808 EHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKL-DFSCICGIKETQNNCLELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSR------------GQMGNRTCE-------------------------HICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL-------------------------------SNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE---DKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN--------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFY----LSTVD----------------------------GRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
+HG V C C G+ G C+ C C +G + D L ++ C C + +C + C S C NGG C C+C GF G C+ ++N CS+ ++G+ C C G+ +C C GF N + C C G V + NC+C W G++C +DVDEC L P CQ C NT G Y C C G+T +G+ + C N CN+ +C +NG IC C SG+ G CS D+DEC + CEH C+N GSF CQC G+T +I+ +CIS C + + +C C PGY G CE N SPC HN ++ NE +C+CPKGF G LC+ D++EC + T C++ C + ++ C C G+ D C P C +G C + C+C+ GY G C+ +INEC +S C H C + + SY C C+ G +C+ C + CD +C C+ G+TG +C+V+IDEC + C + ++C C ++ LS V+ G +C N+ C S+PC NGG C + C C+ G++G +C+ +INEC + + C+ G C + Y+C CP Y TC++ +P C N GVC++ C CP G+ G C VD++EC + +PC + C NT GS+ C C + Y
Sbjct: 78 DHGGTVDYACSCPLGFSGPLCLTPLDNACLANP---CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFESSYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGHCMD-------------------------------KINEFQCQCPKGFNGHLCQYDVDECAS-TPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP--------DPCHYGSCKDGVATFTCLCQPGYTGHHCETNINEC--HSQPCRHGGTCQDRDNSYLCLCLKG----TTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINEC----ASNPCLNQGTCIDDVAGYKCNCPLPYT----GATCEVVLAPCATSP-CKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVK-SPC-RHGASCQNTNGSYRCLCQAGYT 900 HSP 3 Score: 175.252 bits (443), Expect = 9.501e-44 Identity = 210/716 (29.33%), Postives = 298/716 (41.62%), Query Frame = 1
Query: 1015 SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ-------LDNDGKSCIKEECSKFGTTEVVSGN---CKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCL----NGICYCFSGWHGEDCSLDIDECKYNHG-CEH--LCVNVPGSFNCQC---HSGFTLQINKKKCISKSCNIECLNGGLC-----DKDKCKCPPGYIGHNCEFN------DFCHFISPCEHNCTTINDNMVCSCLP---GYDLMPDKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQ-HVCTNTIGSFFCRCKNGHK--LAEDKRSCI--PPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHF--CMNTEGSYKCSCMPGFI-----LSAN---SHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCY---CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
S C NGG C C C+ F G +CQ + N C N H+ + G ++ C C GF LDN +C+ C GT ++++ C+C GW GK C D C N C G CL + IC C G+HG C D++EC N G C H C N GS+ C C H+G ++ C C NGG C +C C PG+ G NCE N + C C T N C C P G D C+ + GTC+ C C G+ G C +I++C + Q C + + SF+C C +G L +CI P N+ + D + V+G+ C C SGY G C +D++EC ++ CEH C+NT GS++C C+ G+ + N S+ CQ+ + C + +F +C C G+ G C+++ DEC C HN C++ + C C F +G C D C+S PCKNG KC++ C C GY G CE DI+EC P H G C++ + C+C PGY C+ + + P C +GG C+D Y C G G +C +++D+C PCD G C + + C C Y
Sbjct: 28 SGTCLNGGRCEVANGTEACVCSGAFVGQRCQ-DSNPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDN---ACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ-ADPCAS-----------------------------------NPCANGGQCLPFESSYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQ----NGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYN----CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAI---CTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQND-ATCLDQIGEF--QCICMPGYEGVYCEINTDECA--SSPCLHNGHCMDKINEFQCQCPKGF-----NGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECD-PDPCH--YGSCKDGVATFTCLCQPGYT----GHHCETNINECHSQP-CRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASN-PCDS--GTCLDKIDGYECACEPGYT 671 HSP 4 Score: 171.4 bits (433), Expect = 1.560e-42 Identity = 230/836 (27.51%), Postives = 334/836 (39.95%), Query Frame = 1
Query: 781 IDNCVPDCGEHGIC----VKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG--------------------------------------CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT-TEVVSGN-CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLS----NGKCAINCLNN---CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF------ILS-----ANSHSCQSVCSLCKNGK--CDFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHG----CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR-----CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICY---NTYGSFYCQCSSNY 2958
ID C PD +G C C C+ G+ G C E Q C HG + R + C+C T NC + L C+ C NGGTC G C+C EG+ C E+N C+ + C H +G N ++C C G+ N + C C GT ++ SG C C++G+ G C +++EC C Q C++ + Y+C+C +T + CA + N C ++ D + C C +GW G+ C +DI+EC + HG C N GS+ C C +G+T + N + I C NGG C + C C PG+ G CE + +PC++ NCT D+ C+C G++ + PD CV G N C CP GF G C+ D+NEC D R C+ + TC D + KC C GY G C + C C T Y C C G+ +LS A V LC++G D +K C C+ G+TG C+ ++DEC N + C + G +SC C ++ G +C E+ + C S PC+NGG C++ KC C G G CE ++++C P+ C G C + G Y C CPPG++ + C+ + + NP C G + R C C G G C ++ C R PC K G+C NT F C+C + +
Sbjct: 567 IDECDPDPCHYGSCKDGVATFTCLCQPGYTGHHCETNINECHSQP----CRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECN-----SNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGAS--CQNTNGSYRCLCQAGYTGR-NCESDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCPVGFNGIHCENNTPDCTESSCFNGGTCVDGI-NSFTCLCPPGFTGSYCQYDVNEC-----------------------------DSRPCL--HGGTCQDSYGTY------KCTCPQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQYHCECRSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYH-----GSNCSEEINECLSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFV----GERCEGDVNECLSNP-CDPRGTQNCVQRVNDFHCECRAGHTGRRCESVINGC-RGKPC-KNGGVCAVASNTARGFICRCPAGF 1340 HSP 5 Score: 150.599 bits (379), Expect = 3.529e-36 Identity = 210/738 (28.46%), Postives = 297/738 (40.24%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQT---------ICQH--VCTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQSVCSLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD--TMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGV 2859
C+HG D + C C + NC + C S C NGGTC C C EGF G CQ IN C+ + C+N+G ++C C +G + C C G + + S +C C GW+G+ C D++EC+ C+ C NT GSY+C C+ G+T + +C N C+ G C +GI C C G+ G C DI+EC N C++ C + S+ C C GF + N C SC NGG C + C CPPG+ G C+++ PC H C C+C GY + + + + C G T + C+C G+ G+ C+ C +CQH +C + +C C+ G+ + ++ C P N TC D + F+ KC+ +GY G C E+INEC S C++ C++ SYKCSC G N C FNN C C G+ GE C+ D++ECL N + NCV + C C + GR C + C PCKNGG C + C+C G+ G +CE D C +G G C + + C+C L CQ NP C N G C S RC CP F+G+ C +
Sbjct: 725 CIHGACRDGLN-GYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNP-CQNGANCTDCVDSYTCTCPVGFNGIHCENNTPDCTESSC----FNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQYHCECRSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTD----YLGGFSCKCV--AGYHGSNCSEEINEC--LSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECR-----AGHTGRRCESVINGCRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCENDARTCGSLRCLNG--GTCISGPRSPTCLC----LGSFTGPECQFPASSPCVGSNP-CYNQGTCEPTSENPFYRCLCPAKFNGLLCHI 1427 HSP 6 Score: 86.6557 bits (213), Expect = 1.426e-16 Identity = 116/444 (26.13%), Postives = 165/444 (37.16%), Query Frame = 1
Query: 784 DNCVPDCGEH-----GICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLEL-RTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQL-----EINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQC---HSGFTLQINKKKCIS----KSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCE----HNCTTINDNMVCSCLPGYDLMP--------DKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC 1968
+N PDC E G CV C C G+ G C E C R C+HG + + C C T NC L R C S C+NGG C+Q C+C G+ G C + E+ + RG C+H +CV+EG+ ++ C C+ G+ G +C D+VDEC CQ C + +G + C C +G+HG +CS +I+EC + C++ C+++ S+ C C G +IN C S + +C N G C C CPPG++G CE + +PC+ NC ++ C C G+ K CK T C+CP GF G CEND C
Sbjct: 981 ENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNE-CDSRP---CLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQYHCECRSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHY----------------------------------CHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKC---------------------------------VAGYHGSNCSEEINEC-LSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGHTGRRCESVINGCRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCENDARTC 1352
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Notch2 (notch 2 [Source:MGI Symbol;Acc:MGI:97364]) HSP 1 Score: 199.904 bits (507), Expect = 1.565e-51 Identity = 242/797 (30.36%), Postives = 345/797 (43.29%), Query Frame = 1
Query: 802 CGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT---TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCL---NNCNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQCHSGFTLQI--NKKKCISKSCNIECLNGGLCDKDK------CKCPPGYIGHNC-EFNDFCHFI--SPCEH--NCTTINDNMVCSCLPGYDLMP---DKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGH-----KLAEDKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHF-CMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKC-DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHN-CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTM 2994
C G+ K+ C C G+ GE C C + C R + C C + T C C S C+NG TC Q C+C G G +C+ +IN C + R C+H C+N +++C+C GF D+ C C GT T + C C G++G C ++D+C CQ +CV+ + +Y C C +T + CL N C G C N C C +GW G+DCS +ID+C Y C++ SF+C C G + CIS C+ G LCD + C CP GY G +C E D C +PCEH C + C CL GY D C C TC + C C GF G+ CE ++NEC N + C + + F C C G ++ D S P N C+D H + +C C +G+ G CDE+I+ C C H C + SY C C PG+ I S C S L +G+C D N +C C+ G +G C+++ D+C N C H CV+ YSC C+ F G+ C D C+S PC+ G C+N +C C G + SC +NEC +S G C Y+C+C G++ ++ C++ + + NP C NGG C ++ RC C GF G +C V++DEC PC +G C++ + C C +L Y G +C T+
Sbjct: 79 CVPQGMLGKATCRCAPGFTGEDCQYSTSHPCFVSRPCQNGGTCHMLSRDT-YECTCQVGFTGKQCQWTDACLSHPCENGSTCTSVASQFSCKCPAGLTGQKCEADINEC---DIPGR-CQHGGTCLNL-PGSYRCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAYASCTPGSTCIDRVASFSCLCPEGKAGLLCHLDDACISNPCH----KGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQN--DATCLDKIGGFTCLCMPGFKGVHCELEVNECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCID----HPNGY--ECQCATGFTGILCDENIDNCDP--DPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCL-NDGRCIDLVNGYQCNCQPGTSGLNCEINFDDCASN--PCMHGVCVDGINRYSCVCSPGFT-----GQRCNIDIDECASNPCRKGATCINDVNGFRCICPEGPHHPSCYSQVNEC---LSNPCIHGNCTGGLSGYKCLCDAGWVGVN----CEVDKNECLSNP-CQNGGTCNNLVNGYRCTCKKGFKGYNCQVNIDECASN-PCLN-QGTCFDDVSGYTCHC----MLPYTGKNCQTV 833 HSP 2 Score: 199.519 bits (506), Expect = 2.442e-51 Identity = 246/862 (28.54%), Postives = 351/862 (40.72%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC--SKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFP--VCQQ--ICVNTIGSYQCSCREGFT-------------------------------LLSNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKY--NHGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDL---MPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH-VCTNTIGSFFCRCKNGHKLA---------------EDKR----------SCIPP--------NKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN--------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCY---CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMT-MKEAVLKP 3015
C C+ G+ G++C + L C +G + FSC C T C ++ C CQ+GGTC RCQC +GF G C C+ N C G+ F+C C GF+ + + C +C G V + NC+C W G+FC +DVDECL CQ C N G Y C C G++ L GK + C N C+K C LNG IC C G+ G DC+ D+DEC ++ CEH CVN G+F+C+C G+ +++ +C S C + CL+ GG C C PG+ G +CE +PC +N C + C C PG+ D C C KC+ N +C+C GF G+LC+ +I+ C + C H C + I S+ C C G+ A D R +C P N C C+HG C + C+C G+ G+RC+ DI+EC C+N ++C C G + SC S + C + C N KC C GW G C+VD +ECL N + C N Y C+C F G +C D C+S PC N G C + C C Y G +C+ + C ++ + + F ++ C+C PG+ K C + + + P C+N GVC + Y CP GF G+DC D+++C PC G C + +F CQC ++ G C T M E + +P
Sbjct: 130 ECTCQVGFTGKQCQWTDACLSHP-----CENGSTCTSVASQFSCKCPAGLTGQKCEADINECDIPGRCQHGGTCLNLPGSYRCQCPQGFTGQHCDSPYVPCAPSPCVNGG---TCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAYASCTPGSTCIDRVASFSCLCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGF----TCLCMPGFKGVHCELEVNECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP-NGYECQCATGFTGILCDENIDNC-DPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGLNCEINFDDCASNPCMHGVCVDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINDVNGFRCICPEG----PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGVNCEVDKNECLSNPCQNGGTCNNLVNGYRCTCKKGF-----KGYNCQVNIDECASNPCLNQGTCFDDVSGYTCHCMLPYTGKNCQTVLAPCSPNPCENAAVCKEAPNFESFSCLCAPGW----QGKRCTVDVDECISKP-CMNNGVCHNTQGSYVCECPPGFSGMDCEEDINDC-LANPCQN-GGSCVDHVNTFSCQCHPGFI----GDKCQTDMNECLSEP 957 HSP 3 Score: 196.823 bits (499), Expect = 1.781e-50 Identity = 241/795 (30.31%), Postives = 337/795 (42.39%), Query Frame = 1
Query: 778 AIDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLD----FSCICGIKETQNNC-LELRTC-SKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ-------LDN-DGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQC-----HSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKD-CVHGQCFNS-KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGK--CDFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVC---RDMSRCYCPIGFHGIDCGV-----DVDECQRYAPCDKL---RGICYNTYGSFYCQCSSNYVLMY 2970
A+ N P C G CV + C C G+ G RC ++ C C D LD F+C+C +C LE+ C S C N G C + +C C GF G CQ++I+ CS N C++ N ++C+C +GF +DN D C +C + S C C G+ G C+D +DEC C C++ + YQC+C+ G + L+ C IN C +N +G C++GI C C G+ G+ C++DIDEC N C C+N F C C H Q+N+ C+S C GGL KC C G++G NCE + +PC++ TC L N +C C KGF G C+ +I+EC N + Q C + + + C C + + P + C + C F S C+C G++GKRC D++EC + C NT+GSY C C PGF + + + C+NG D N C+C G+ G+ C D++ECL K C + SY+C+C F+ G C D C+ S C NGG CV+ C C G+ G C DINEC S + C+ G C + G Y CICP GY K CQ +P C N G C + C CP G+ G C V Q+ P + L GIC N + +CQC Y Y
Sbjct: 420 AMANSNP-CEHAGKCVNTDGAFHCECLKGYAGPRCE-MDINECHSDP-------CQNDATCLDKIGGFTCLCMPGFKGVHCELEVNECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGA---KCIDH-PNGYECQCATGFTGILCDENIDNCDPDPCHHGQCQD----GIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGLN---CEINFDDCASNPCMHGVCVDGINRYSCVCSPGFTGQRCNIDIDECASNP-CRKGATCINDVNGFRCICPEGPHHPSCYSQVNE--CLSNPCIHGNCTGGLSGY-KCLCDAGWVGVNCEVDKNECLSNPCQNG----------------------GTCNNL---------VNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDVSGYTCHCMLPYTGKNCQTVLAPCSPNPCENAAVCKEAPNFESFSCLCAPGWQGKRCTVDVDECISKPCMNNGVCHNTQGSYVCECPPGFSGMDCEEDINDCLANPCQNGGSCVDHVNTFSCQCHPGFIGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCTCPAGFH-----GVHCENNIDECTESSCFNGGTCVDGINSFSCLCPVGFTGPFCLHDINEC----SSNPCLNAGTCVDGLGTYRCICPLGYT----GKNCQTLVNLCSRSP-CKNKGTCVQEKARPHCLCPPGWDGAYCDVLNVSCKAAALQKGVPVEHLCQHSGICINAGNTHHCQCPLGYTGSY 1145 HSP 4 Score: 186.422 bits (472), Expect = 3.181e-47 Identity = 232/769 (30.17%), Postives = 332/769 (43.17%), Query Frame = 1
Query: 991 NCLELRTCSKGCQNGGTCFQ-----GRCQCTEGFEGDQCQL----EINSCS-------RGQMGNRTCE---------------------HICVNEG------ENNFQCKCQSGFQLDNDGK------SCIKEECSKFGTTEVVSG--NCKCKQGWKGKFCNDDVDECLFP-VCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCL-------NNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFN-DFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLEC---PKCVRGTCNENK------------CKCPKGFAGLLCENDINEC--LNQTICQHV--CTNTIGSFFCRCKNGHKLAE---DKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNG-KC-DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVC-RDMS--RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
+ L+ R + C N GTC G C+C EGF G+ CQ E N C +G +G TC C N G + ++C CQ GF GK +C+ C T V+ +CKC G G+ C D++EC P CQ C+N GSY+C C +GFT + C C + GD C C G+ G C +ID+C NH C++ +CV+ ++NC+C +T Q + +C+ + C NGG C C C G+ G +C N D C + S C T I+ SC L P+ K L C C+ C++ C CP+G+ G C D++EC N C+H C NT G+F C C G+ D C N TCLDK C+C G++G C+ ++NEC+ + C++ ++C C PGF + + C S + C NG KC D N +C+C TG+TG LCD +ID C + C H C + SY+C CN P Y+ + C ++ D C SSPC N G+C++ +C C+PG +G +CE + ++C HG C + Y C+C PG+ + C I + NP C G C D++ RC CP G H C V+EC PC + G C + C C + +V
Sbjct: 24 HALQCRGGQEPCVNEGTCVTYHNGTGFCRCPEGFLGEYCQHRDPCEKNRCQNGGTCVPQGMLGKATCRCAPGFTGEDCQYSTSHPCFVSRPCQNGGTCHMLSRDTYECTCQVGFT----GKQCQWTDACLSHPCENGSTCTSVASQFSCKCPAGLTGQKCEADINECDIPGRCQHGGTCLNLPGSYRCQCPQGFTGQHCDSPYVPCAPSPCVNGGTCRQTGD-FTFECNCLPGFEGSTCERNIDDCP-NHKCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQP--NACQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAYAS-CTPGSTCIDRVASFSC-----LCPEGKA--GLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDK------IGGFTCLCMPGFKGVHCELEVNECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSS--TPCLNGAKCIDHPNGYECQCATGFTGILCDENIDNC--DPDPCHHGQCQDGIDSYTCICN-PGYMGAI----CSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGLNCEINFDDCASNPCMHGV---CVDGINRYSCVCSPGFT----GQRCNIDIDECASNP-CRKGATCINDVNGFRCICPEGPHHPSCYSQVNECLSN-PC--IHGNCTGGLSGYKCLCDAGWV 750 HSP 5 Score: 180.259 bits (456), Expect = 2.621e-45 Identity = 240/823 (29.16%), Postives = 349/823 (42.41%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLD----FSCICGIKETQNNC-LELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFT----LLSNGKCAIN-CLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPG--SFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLEC---PKCVRGTC----NENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNG-------HKLAE-DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF------IL-----SANSHSCQSVCSLCKNGKCDFN----NKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQ-WPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGV----CRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRG----ICYNTYGSFYCQCSSNYVLMYDGTSCMTMK 2997
IDNC PD HG C C C G+ G +C + C D R +D + C C + NC + C+ G C G C C+ GF G +C ++I+ C+ C+N+ N F+C C G + C+ C T +SG C C GW G C D +ECL CQ C N + Y+C+C++GF ++ +CA N CLN D C+C + G++C + C N CE+ +C P SF+C C G+ + ++ +CISK C +N G+C + C+CPPG+ G +CE + +PC++ +C + C C PG+ + DK EC P GTC N C CP GF G+ CEN+I+EC + C + I SF C C G H + E C+ N TC+D + +CIC GY GK C +N C + + C+ + C C PG+ +L +A V LC++ N + C+C G+TG C+ +DEC N CQH C + G Y C C +P Y G +C + D C + PC+NGG C++ KC C PG G CEE+I+EC P +G G+C + G Y C C PG+ + C+ + + NP G + ++ C C F G C +D C + PC L G + N F C+C + +SC +K
Sbjct: 571 IDNCDPDPCHHGQCQDGIDSYTCICNPGYMGA--------ICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGLNCEINFDDCASNPCMHGVCVDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGA---TCIND-VNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGVNCEVDKNECLSNPCQNGGTCNNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDVSGYTCHCMLPYTGKNCQTVLAPCSPNP-CENAAVCKEAPNFESFSCLCAPGWQGKRCTVDVDECISKPC----MNNGVCHNTQGSYVCECPPGFSGMDCEEDINDCLANPCQNGGSCVDHVNTFSCQCHPGF--IGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCTCPAGFHGVHCENNIDECTESSCFNGGTCVDGINSFSCLCPVGFTGPFCLHDINECSSNPCL--NAGTCVDGLGTY------RCICPLGYTGKNCQTLVNLCSRSPCKNKGTCVQEKARPHCLCPPGWDGAYCDVLNVSCKAAALQKGVPVEHLCQHSGICINAGNTHHCQCPLGYTGSYCEEQLDECASN--PCQHGATCNDFIGGYRCEC-VPGY----QGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDECAGGPHCLNG--GQCVDRIGGYTCRCLPGFA----GERCEGDINECLSNPCSSEGSLDCVQLKNNYNCICRSAFTGRHCETFLDVCPQ-KPC--LNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVK 1350
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Notch3 (notch 3 [Source:MGI Symbol;Acc:MGI:99460]) HSP 1 Score: 199.134 bits (505), Expect = 3.152e-51 Identity = 230/819 (28.08%), Postives = 334/819 (40.78%), Query Frame = 1
Query: 943 RKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGTTE-VVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN----GDCLNGI----CYCFSGWHGEDCSLDIDECK--------------------------------YNHGCEH------LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIE-CLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNM-VCSCLPGYDL---MPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNG---HKLAEDKRSCI--PPNKKTCLD----------------------KDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-------CKTGWTGELCDVDIDEC--------LLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP------HCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYA-PCDKLRGICYNTYGSFYCQCSSNYV 2961
R F+CIC T C +++ C S C NGG C C C GF G CQL+++ C+ N CV++ + ++C+C GF+ + + C + C + + S +C C G+ G C VDEC C+ C++ + Y C C G T ++ C +N +++C N G C +GI C C G+ G C+++I+EC NH C H +C + PG F C C G++ + +C + C GG C D +C C PG+ GH CE C S CEH +C + D + VCSC PG+ D C P GTC +C C +G+ G C+ DI++C + C H C + +GSF C C +G + A D C+ P TC D DC CFN C+C+ GY G C + + C +S C H C T ++C+C GF S CQ+ C C +C C GW+G LCD+ C + + CQ C++ S+ C C G C + D C++ PC++GG C C+C GY GDSCE++I+EC ++G G C + Y C CPPG L + C+I+ D P CL+ G C D+ RC CP G+ G+ C D++EC+ A R + G F C C +
Sbjct: 450 RIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVDECASTPCRNGA---KCVDQ-PDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGTTGVN---CEVN-IDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCSHGVCHDAPGGFRCVCEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFRCTCAPGFQGHQCEVLSPC-TPSLCEHGGHCESDPDRLTVCSCPPGWQGPRCQQDVDECAGAS-PCGPHGTCTNLPGNFRCICHRGYTGPFCDQDIDDC-DPNPCLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLSSPCGPGTCTDHVASFTCACPPGYGGFHCEIDLPDCSPSSCFNGGTCVDGVSSFSCLCRPGYTGTHCQYEADPC--FSRPCLHGGICNPTHPGFECTCREGFTGS----QCQNPVDWCSQAPCQNGGRCVQTGAYCICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQLCQEGGKCIDKGRSHYCVCP-----EGRTGSHCEHEVDPCTAQPCQHGGTCRGYMGGYVCECPAGYAGDSCEDNIDECASQPCQNG--GSCIDLVARYLCSCPPGTLGV----LCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGACHAAHTRDCLQDPGGHFRCVCHPGFT 1240 HSP 2 Score: 194.126 bits (492), Expect = 1.083e-49 Identity = 243/864 (28.12%), Postives = 340/864 (39.35%), Query Frame = 1
Query: 802 CGEHGICVKS--------RCYCETGWFGERCVILEPELCKQRKLLFCVHG--CSF--DKRKLDFSCICGIKETQNNCL-ELRTCSKG--CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLLS-------------------------------NGKCAI------NCLNN-------CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSC----------------------------------NIECLNGGLCDKDK-----CKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI----LSANSHSCQSVCS--LCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVN-----SKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C G+C S C C G+ G C +P+ C R CVHG CS D R F+C C +C ++ C G C++GGTC RCQC G+ G C+ + C+ N C + + C C GF+ N + C C GT V + NC+C W G+FC +DVDEC L P C C N +G + C C G+T S GK + C++N C+ N IC C G+ G C D+DEC + CEHL CVN GSF CQC G+T + + +C+S C + C+NGG+C KD+ C CP G+ G C+ + +PC + C D C C G++ ++ C G C + C C G+ G+ CE+ ++EC +Q C++ C + + + CRC G + N C C G C + C+C+ G+ G C+ +INEC C++ E + C C PG + L AN CS +C + F +C C+ GW+G C + CQ C + + C+C F G C + S C++GG C + + C C PG+ G C++D++EC S G G C N GN+ CIC GY C D NP CL+GG C+D C C GF G C DVDEC +PC G C + SF C C Y
Sbjct: 88 CAGRGVCQSSVVAGTARFSCRCLRGFQGPDCS--QPDPCVSRP---CVHGAPCSVGPDGR---FACACPPGYQGQSCQSDIDECRSGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCENPVVPCAPSPCRNGG---TCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVC-KDRVNGFSCTCPSGFSGSMCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQP-CRYGGKCLDLVDKYLCRCPPGTTGVNCEV-----NIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCSHGVCHDAPGGF--RCVCEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFRCTCAPGF-----QGHQCEVLSPCTPSLCEHGGHCESDPDRLTVCSCPPGWQGPRCQQDVDECAG-ASPCGPHGTCTNLPGNFRCICHRGYT----GPFCDQDIDDCDPNP-CLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLS-SPCGP--GTCTDHVASFTCACPPGY 917 HSP 3 Score: 171.785 bits (434), Expect = 1.161e-42 Identity = 215/742 (28.98%), Postives = 302/742 (40.70%), Query Frame = 1
Query: 955 FSCICGIKETQNNC-LELRTCSKG-CQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQSGF-----QLDNDGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEHN-CTTINDNMVCSCLPGYD-------LMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH------------VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQS-VCSLCKNGKCD---FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGY--LVLDDQK---TCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
F C CG T C ++ C G C+N TC Q C C GF G C+++I+ C CVN G N F C C SGF QLD D C C + C+C +G++G C +VD+C C CV+ I S+ C+C G+T + C + C G CL+ + C C G G +C ++ID+C N +C + ++C C GFT + + I++ + C GG C + C CPPG + C + PC H C C C PG+ L PD C+ C GTC + +C C GF G CE ++ C ++C+H VC+ G RC+ C P HG C N +CIC GY G CD+DI++C + C + GS+ CSC+ GF + + S C G C + C C G+ G C++D+ +C + CV+ S+SC C P Y T C + D C S PC +GG C + +C C+ G+ G C+ ++ C ++G G C T G Y CICPPG+ + D Q T + C GG C D R C CP G G C +VD C PC + G C G + C+C + Y
Sbjct: 416 FLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQ---------SSPCVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVD--ECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCERNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVE-INECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCSHGVCHDAPGGFRCVCEPGWSGPRCSQSLAPD--ACESQPCQ--AGGTCTSDGIGFRCTCAPGFQGHQCEV-LSPC-TPSLCEHGGHCESDPDRLTVCSCPPGWQGPRCQQDVDECAGASPCGP------------HGTCTNLPGNFRCICHRGYTGPFCDQDIDDCDPNPCLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLSSPCGPGTCTDHVASFTCACPPGYGGFHCEIDLPDCSPSSCFNGGTCVDGVSSFSCLCR-PGYTGT----HCQYEADPCFSRPCLHGGICNPTHPGFECTCREGFTGSQCQNPVDWCSQAPCQNG--GRCVQT-GAY-CICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQLCQEGGKCIDKGRSHYCVCPEGRTGSHCEHEVDPCTAQ-PC-QHGGTCRGYMGGYVCECPAGYA 1116 HSP 4 Score: 154.066 bits (388), Expect = 3.065e-37 Identity = 218/826 (26.39%), Postives = 318/826 (38.50%), Query Frame = 1
Query: 811 HGICVKS----RCYCETGWFGERCV-ILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKG-CQNGGTCFQGR-----CQCTEGFEGDQCQLEINSCSRGQMGNRTC-EHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGTTE--VVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLN----NCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK--CKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPG----------YDLMPDKKTCK--KLECPKCV----------RGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGH-----KLAEDKRSCIPPNKKTCLDK--DCVH-GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHF---CMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGEL--------------CDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCL--------EKNDSCSS-PCKNGGKCVNS------KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCS-SNYVLMYDGTSCMT 2991
HG+C + RC CE GW G RC L P+ C+ + C G + + F C C + C L C+ C++GG C C C G++G +CQ +++ C+ G C H NF+C C G+ D D C C G+ + V S +C C G+ G C DVDECL C C + + S+ C+C G+ C I+ + +C G C++G+ C C G+ G C + D C ++ C H +C F C C GFT + + C NGG C + C CPPG+ G C+ PC + + C G Y + P+ +T + E C RG C+CP G+AG CE++I+EC +Q CQ+ C + + + C C G ++ ED P LD C+H G C + +C C GY G C+ DINEC+ + H + G ++C C PGF CQ S C++ C +C+ G G L C+ C Q C + C+C P LS G SC N SC+S PC +GG C+ +C C PG+ G CE + P E CP + CQ D C+ C G G+ G DC ++VD+ R C+ L+ C+ + + C + S+ +YD C +
Sbjct: 707 HGVCHDAPGGFRCVCEPGWSGPRCSQSLAPDACESQP---CQAGGTCTSDGIGFRCTCAPGFQGHQCEVLSPCTPSLCEHGGHCESDPDRLTVCSCPPGWQGPRCQQDVDECA----GASPCGPHGTCTNLPGNFRCICHRGYTGPFCDQDIDDCDPNPCLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLSSPCGPGTCTDHVASFTCACPPGYGGF---HCEIDLPDCSPSSCFNGGTCVDGVSSFSCLCRPGYTGTHCQYEADPC-FSRPCLHGGICNPTHPGFECTCREGFTGSQCQNP-VDWCSQAPCQNGGRCVQTGAYCICPPGWSGRLCDIQSL-----PCTEAAAQMGVRLEQLCQEGGKCIDKGRSHYCVCPEGRTGSHCEHEVDPCTAQPCQHGGTCRGYMGGYVCECPAGYAGDSCEDNIDECASQP-CQNGGSCIDLVARYLCSCPPGTLGVLCEINEDDCDLGP-----SLDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGACHAAHTRDCLQDPGGHFRCVCHPGF----TGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTCHCVPPFWGLRCERVARSCRELQCPVGIPCQQTARGPRCAC--PPGLS---GPSCRVSRASPSGATNASCASAPCLHGGSCLPVQSVPFFRCVCAPGWGGPRCETPSAAPEVP----------------EEPRCP--------RAACQAKRGDQNCDRECNTPGC-----------GWDGGDCSLNVDDPWRQ--CEALQ--CWRLFNNSRCDPACSSPACLYDNFDCYS 1461 HSP 5 Score: 150.984 bits (380), Expect = 2.784e-36 Identity = 212/775 (27.35%), Postives = 304/775 (39.23%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLD----FSCICGIKETQNNC-LELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLD---NDGKSCIKEECSKFGTTEVVSG-NCKCKQGWKGKFCNDDV--DECLFPVCQQ--ICVNTIGSYQCSCREGFT-----LLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGC--EHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPC-EHNCTTINDNMVCSCLPGYDL------MPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSK--CICKSGYRGKRCDEDINECK--------KYSHICEHF--CMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK---------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC--------SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGEC-RNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCR-DMSR-------CYCPIGFHGIDC 2853
+D+C PD HG CV C C G+ G RC E C+ + C + + LD + C C T NC + + C+ G C G C C GF G C +EIN C+ G CV+ GEN F C C G C + CS + G C C+ GW G C+ + D C CQ C + ++C+C GF +LS ++ +C + D L +C C GW G C D+DEC C C N+PG+F C CH G+T + I CL+GG C C C G+ G C + SPC CT + C+C PGY +PD CV G + C C G+ G C+ + + C ++ C H +C T F C C+ G ++ + ++ C + G+C + CIC G+ G+ CD C + +C+ C++ S+ C C G SH C+ C C C+ C G+ G+ C+ +IDEC + +C++ Y CSC P L + C D C C + G CV+ +C C PGY G CE DINEC+ +C ++ G++ C+C PG+ CQI+ P C +GG CR + R C+C F G+ C
Sbjct: 547 VDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDE-CRSQP-------CRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGG---SCVD-GENGFHCLCPPGSLPPLCLPANHPCAHKPCSHGVCHDAPGGFRCVCEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFRCTCAPGFQGHQCEVLSPCTPSLCEHGGHCESDPDRLT-VCSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGNFRCICHRGYTGPFCDQD-IDDCDPNPCLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLSSPCGPGTCTDHVASFTCACPPGYGGFHCEIDLPDCSPSSCFNGGTCVDGV-SSFSCLCRPGYTGTHCQYEADPCFSRP-CLHGGICNPTHPGFECTCREGFTGSQCQNPVDWCSQAPCQNG----GRCVQTGAYCICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQLCQEGGKCIDKGRSHYCVCPEG---RTGSH-CEHEVDPCTAQPCQHGGTCRGYMGGYVCECPAGYAGDSCEDNIDECASQPCQNGGSCIDLVARYLCSCP-PGTLGVL----CEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECRPGACHAAHTRDCLQDPGGHFRCVCHPGFT----GPRCQIALSPCESQP-CQHGGQCRHSLGRGGGLTFTCHCVPPFWGLRC 1287 HSP 6 Score: 146.362 bits (368), Expect = 7.857e-35 Identity = 134/467 (28.69%), Postives = 200/467 (42.83%), Query Frame = 1
Query: 1672 CLNGGLCDKDK------CKCPPGYIGHNCEFNDFCHF-----ISPCEHNCTTINDNMVCSCLPGYD----LMPDKKTCKK-LECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLD-KDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMP---GFILSANSHSCQSVCSLCKNGKCDFN----NKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCL--EKNDSC-SSPCKNGGKCVNSK------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C NGG C + C C PG++G C+ D CH C+ + C CL G+ PD + + C G C CP G+ G C++DI+EC + T C+H C NT GSF C+C G+ + +P C + C C C G+ G+ C+ ++++C + + C++ +Y C C P G + + CQ + C NG FN + C C GWTGE C +ID+C C + S+ C+C + G++ L +D+C S+PC C + C C PG+ G +C++D++EC + +G C NT G++ C C GY C+ + + P C N C D C C GF G C VD+DECQ +PC G+C + F C C S +
Sbjct: 49 CANGGRCTHQQPSLEAACLCLPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCLRGFQGPDCSQPDPCVSRPCVHGAPCSVGPDGRFACACPPGYQGQSCQSDIDECRSGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCENPVVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPM--------GKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT----GPRCETDVNECLSGP-CRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQS-SPCVN-GGVCKDRVNGFSCTCPSGF 500
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Tnxb (tenascin XB [Source:MGI Symbol;Acc:MGI:1932137]) HSP 1 Score: 199.134 bits (505), Expect = 3.160e-51 Identity = 184/692 (26.59%), Postives = 274/692 (39.60%), Query Frame = 1
Query: 616 CKPPFCLPRRCDQIDCGQSNCITNSRPCARNNQDCSMEQKRVLFGSEVVCL---NKPAID--NCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNT--IGSYQCSCREGFTLLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDI--DECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVRGT--CNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAED--KRSCIPPNKKTCLDKDCV-HGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSA-NSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQ 2637
C+P + P D D + T+S P +DC+ +Q R + G VC + P+ +C DC G CVK C C G+ G P+ C QR C C+ R + C+C + +C +R+C +GC G C G C C G+ G+ C + +C RG CE + +C C G+ ++ +C G V G C C G+ G ++C C + C +C C G+ S C + +C +CN+ G C +G C C+ G+ G DCS +C+ CE C CH+G++ + C +SC +C G C+ +C C PGY G +C C +C + C C PG+ + C CP RG C C C G++G C C + + C N + C C G+ ED R C +DC HG C + C+C +GY G+ C I C C +G +C C PG+ A + +C + C G+C C C G++GE C + C + G C C F G C + +C C++ G+C+ +C C+ GY GD C E+I Q
Sbjct: 147 CEPGWGGPTCSDPTD---TKTPTSSPPSKSCPEDCN-DQGRCVRG-RCVCFPGYSGPSCSWPSCPGDCQGRGRCVKGVCVCRAGFSG-------PD-CSQRS---CPRNCNQRGRCEEGRCVCDPGYSGEDC-GVRSCPRGCSQRGRCENGLCVCNPGYSGEDCG--VRNCPRGCSQRGRCE---------DGRCVCDPGYSGEDCSMRTCPWDCGDGG--RCVDGRCVCWPGYSG-------EDCSTRTCPRDCRGRGRCEDGECICDAGY---SGDDCGVRSCPGDCNQRGHCEDGRCVCWPGYTGADCSTRACPRDCRGRGRCEDGV--------CVCHAGYS----GEDCGVRSCPGDCRGRGNCESGRCVCWPGYTGRDCG-------TRACPGDCRGRGRCVDGRCVCNPGFT----GEDCGSRRCPGDCRGHGHCENGVCVCAVGYSGDDCST--RSCPSDCRGRGQCLNGL----CECDEGYS-GEDCGIRRC---------PRDCSQHGVCQDGLCMCHAGYAGEDCS--IRTCPAD---CRRRGRCEDG--RCVCNPGYTGPACATRTCPADCR--GRGRC-VQGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQ--CVCVEGF-----RGPDCAIQ--TCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQ 740 HSP 2 Score: 194.897 bits (494), Expect = 8.779e-50 Identity = 192/733 (26.19%), Postives = 287/733 (39.15%), Query Frame = 1
Query: 802 CGEHGICVKSRC--YCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTC-EHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPKCVRGT--CNENKCKCPKGFAGLLC--ENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCV-HGQCFNSKCICKSGYRGKRCDED--INECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKN-GKCDFNNKCKCKTGWTGELCDVDIDECLLNQHK-CQHNCVNSNGSYS-----------------------CSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGEC--RNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQ 2877
C HG+ SRC CE GW G C +P K T + ++C + C + G C +GRC C G+ G C SC G C + +CV C++GF + + C++ G E G C C G+ G+ C V C Q+ C N + C C G+ S C + NC C++ G C +G C C G+ GEDCS+ C ++ G CV+ C C G++ + C +++C +C G C+ +C C GY G +C + C +C ++ C C PGY C CP+ RG C + C C G++G C + +C + C+ S C C G+ R C + C DC G+C + +C+C G+ G+ C +C+ + H CE+ C C G+ S + S +S S C+ G+C N C+C G++GE C + +QH CQ + Y+ C CN P Y G +C + +C + C+ G+CV C C GY+G+ C ++ + P S C G C R +C+C G+ D C I T C C + G C RC C G+ G DCG ++ Q
Sbjct: 132 CSLHGVFDLSRCACSCEPGWGGPTCS--DPTDTK----------------------------TPTSSPPSKSCPEDCNDQGRCVRGRCVCFPGYSGPSCSWP--SCPGDCQGRGRCVKGVCV----------CRAGFSGPDCSQRSCPRNCNQRGRCE--EGRCVCDPGYSGEDCG--VRSCPRGCSQRGRCENGL----CVCNPGY---SGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDCSMRT--CPWDCGDGGRCVD----GRCVCWPGYS----GEDCSTRTCPRDCRGRGRCEDGECICDAGYSGDDCG-------VRSCPGDCNQRGHCEDGRCVCWPGYT----GADCSTRACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDCRGRGNCE--------SGRCVCWPGYT----GRDC---GTRAC-PGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGH-CENGV--------CVCAVGY--SGDDCSTRSCPSDCRGRGQC-LNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQDGLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCN-PGY----TGPACATR--TCPADCRGRGRCVQGVCMCYVGYSGEDCGQE----EPPAS--ACPGGCGPRELCRAGQCVCVEGFRGPD----CAIQT----CPGDCRSRGECIQ-GRCVCQEGYAGDDCGEEIPAIQ 740 HSP 3 Score: 178.333 bits (451), Expect = 1.186e-44 Identity = 157/616 (25.49%), Postives = 235/616 (38.15%), Query Frame = 1
Query: 1219 GKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDI--DECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPK--CVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCV-HGQCFNSKCICKSGYRGKRCD--EDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYS--CSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYE---CICPPGYLVLDDQKTCQISTKDTMCNPHCLNG-------------------------GVCRDMSRCYCPIGFHGIDCGVDV--DECQRYAPCDKLRGICYNTYGSFYC 2940
G++ ++ CS G ++ C C+ GW G C+D D ++ + +C +CN G C+ G C CF G+ G CS +C+ C V G C C +GF+ C +SC C G C++ +C C PGY G +C + C C+ +N +C C PGY + C CP+ RG C + +C C G++G C + C C + RC +G + S + +TC +DC G+C + +CIC +GY G C +C + H CE +C C PG+ ++ +C C G+C+ + C C G++GE C V C +C S C C P Y GR C + +C C+ G+CV+ +C C PG+ G+ C C G+CR G+ E C+C GY D + + D CLNG GVC+D C C G+ G DC + +C+R C+ R +C Y C
Sbjct: 124 GQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDT-------------------------KTPTSSPPSKSCPEDCNDQGRCVRGRCVCFPGYSGPSCSWPSCPGDCQGRGRC------VKGV--CVCRAGFS----GPDCSQRSCPRNCNQRGRCEEGRCVCDPGYSGEDCG-------VRSCPRGCSQRGRCENGLCVCNPGY----SGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDC--------SMRTCPWDCGDG-----GRCVDGRCVCWPGYSGEDCSTRTC-PRDCRGRGRCEDGECICDAGYSGDDCGVRSCPGDCNQRGH-CE--------DGRCVCWPGYTGADCSTRACPRDCR--GRGRCE-DGVCVCHAGYSGEDCGV---------RSCPGDCRGRGNCESGRCVC-WPGY----TGRDCGTR--ACPGDCRGRGRCVDGRCVCNPGFTGEDC-----------GSRRCPGDCRG-HGHCENGVCVCAVGY--SGDDCSTRSCPSDCRGRGQCLNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQD-GLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCNPGYTGPAC 634 HSP 4 Score: 67.3958 bits (163), Expect = 1.123e-10 Identity = 39/117 (33.33%), Postives = 51/117 (43.59%), Query Frame = 1
Query: 778 AIDNCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQM 1128
A C DC G CV+ C C G+ GE C EP C GC + C+C +C ++TC C++ G C QGRC C EG+ GD C EI + +M
Sbjct: 635 ATRTCPADCRGRGRCVQGVCMCYVGYSGEDCGQEEPPASA------CPGGCGPRELCRAGQCVCVEGFRGPDC-AIQTCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQNMRM 744
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Tnxb (tenascin XB [Source:MGI Symbol;Acc:MGI:1932137]) HSP 1 Score: 197.208 bits (500), Expect = 1.469e-50 Identity = 183/692 (26.45%), Postives = 274/692 (39.60%), Query Frame = 1
Query: 616 CKPPFCLPRRCDQIDCGQSNCITNSRPCARNNQDCSMEQKRVLFGSEVVCL---NKPAID--NCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNT--IGSYQCSCREGFTLLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDI--DECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVRGT--CNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAED--KRSCIPPNKKTCLDKDCV-HGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSA-NSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQ 2637
C+P + P D D + T+S P +DC+ +Q R + G VC + P+ +C DC G CVK C C G+ G P+ C QR C C+ R + C+C + +C +R+C +GC G C G C C G+ G+ C + +C RG CE + +C C G+ ++ +C G V G C C G+ G ++C C + C +C C G+ S C + +C +CN+ G C +G C C+ G+ G DCS +C+ CE C CH+G++ + C +SC +C G C+ +C C PGY G +C C +C + C C PG+ + C CP RG C C C G++G C C + + C N + C C G+ ED R C +DC HG C + C+C +GY G+ C I C C +G +C C PG+ A + +C + C G+C C C G++GE C + C + G C C + G C + +C C++ G+C+ +C C+ GY GD C E+I Q
Sbjct: 147 CEPGWGGPTCSDPTD---TKTPTSSPPSKSCPEDCN-DQGRCVRG-RCVCFPGYSGPSCSWPSCPGDCQGRGRCVKGVCVCRAGFSG-------PD-CSQRS---CPRNCNQRGRCEEGRCVCDPGYSGEDC-GVRSCPRGCSQRGRCENGLCVCNPGYSGEDCG--VRNCPRGCSQRGRCE---------DGRCVCDPGYSGEDCSMRTCPWDCGDGG--RCVDGRCVCWPGYSG-------EDCSTRTCPRDCRGRGRCEDGECICDAGY---SGDDCGVRSCPGDCNQRGHCEDGRCVCWPGYTGADCSTRACPRDCRGRGRCEDGV--------CVCHAGYS----GEDCGVRSCPGDCRGRGNCESGRCVCWPGYTGRDCG-------TRACPGDCRGRGRCVDGRCVCNPGFT----GEDCGSRRCPGDCRGHGHCENGVCVCAVGYSGDDCST--RSCPSDCRGRGQCLNGL----CECDEGYS-GEDCGIRRC---------PRDCSQHGVCQDGLCMCHAGYAGEDCS--IRTCPAD---CRRRGRCEDG--RCVCNPGYTGPACATRTCPADCR--GRGRC-VQGVCMCYVGYSGEDCGQEEPPASACPGGCGPRELCRAGQ--CVC-----VEGFRGPDCAIQ--TCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQ 740 HSP 2 Score: 192.586 bits (488), Expect = 4.514e-49 Identity = 192/733 (26.19%), Postives = 287/733 (39.15%), Query Frame = 1
Query: 802 CGEHGICVKSRC--YCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTC-EHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAI-NCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPKCVRGT--CNENKCKCPKGFAGLLC--ENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCV-HGQCFNSKCICKSGYRGKRCDED--INECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKN-GKCDFNNKCKCKTGWTGELCDVDIDECLLNQHK-CQHNCVNSNGSYS-----------------------CSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGEC--RNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQ 2877
C HG+ SRC CE GW G C +P K T + ++C + C + G C +GRC C G+ G C SC G C + +CV C++GF + + C++ G E G C C G+ G+ C V C Q+ C N + C C G+ S C + NC C++ G C +G C C G+ GEDCS+ C ++ G CV+ C C G++ + C +++C +C G C+ +C C GY G +C + C +C ++ C C PGY C CP+ RG C + C C G++G C + +C + C+ S C C G+ R C + C DC G+C + +C+C G+ G+ C +C+ + H CE+ C C G+ S + S +S S C+ G+C N C+C G++GE C + +QH CQ + Y+ C CN P Y G +C + +C + C+ G+CV C C GY+G+ C ++ + P S C G C R +C+C G+ D C I T C C + G C RC C G+ G DCG ++ Q
Sbjct: 132 CSLHGVFDLSRCACSCEPGWGGPTCS--DPTDTK----------------------------TPTSSPPSKSCPEDCNDQGRCVRGRCVCFPGYSGPSCSWP--SCPGDCQGRGRCVKGVCV----------CRAGFSGPDCSQRSCPRNCNQRGRCE--EGRCVCDPGYSGEDCG--VRSCPRGCSQRGRCENGL----CVCNPGY---SGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDCSMRT--CPWDCGDGGRCVD----GRCVCWPGYS----GEDCSTRTCPRDCRGRGRCEDGECICDAGYSGDDCG-------VRSCPGDCNQRGHCEDGRCVCWPGYT----GADCSTRACPRDCRGRGRCEDGVCVCHAGYSGEDCGVRSCPGDCRGRGNCE--------SGRCVCWPGYT----GRDC---GTRAC-PGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGH-CENGV--------CVCAVGY--SGDDCSTRSCPSDCRGRGQC-LNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQDGLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCN-PGY----TGPACATR--TCPADCRGRGRCVQGVCMCYVGYSGEDCGQE----EPPAS--ACPGGCGPRELCRAGQCVCVEGFRGPD----CAIQT----CPGDCRSRGECIQ-GRCVCQEGYAGDDCGEEIPAIQ 740 HSP 3 Score: 176.407 bits (446), Expect = 4.016e-44 Identity = 157/616 (25.49%), Postives = 235/616 (38.15%), Query Frame = 1
Query: 1219 GKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDI--DECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPK--CVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCV-HGQCFNSKCICKSGYRGKRCD--EDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYS--CSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYE---CICPPGYLVLDDQKTCQISTKDTMCNPHCLNG-------------------------GVCRDMSRCYCPIGFHGIDCGVDV--DECQRYAPCDKLRGICYNTYGSFYC 2940
G++ ++ CS G ++ C C+ GW G C+D D ++ + +C +CN G C+ G C CF G+ G CS +C+ C V G C C +GF+ C +SC C G C++ +C C PGY G +C + C C+ +N +C C PGY + C CP+ RG C + +C C G++G C + C C + RC +G + S + +TC +DC G+C + +CIC +GY G C +C + H CE +C C PG+ ++ +C C G+C+ + C C G++GE C V C +C S C C P Y GR C + +C C+ G+CV+ +C C PG+ G+ C C G+CR G+ E C+C GY D + + D CLNG GVC+D C C G+ G DC + +C+R C+ R +C Y C
Sbjct: 124 GQTDVRSLCSLHGVFDLSRCACSCEPGWGGPTCSDPTDT-------------------------KTPTSSPPSKSCPEDCNDQGRCVRGRCVCFPGYSGPSCSWPSCPGDCQGRGRC------VKGV--CVCRAGFS----GPDCSQRSCPRNCNQRGRCEEGRCVCDPGYSGEDCG-------VRSCPRGCSQRGRCENGLCVCNPGY----SGEDCGVRNCPRGCSQRGRCEDGRCVCDPGYSGEDC--------SMRTCPWDCGDG-----GRCVDGRCVCWPGYSGEDCSTRTC-PRDCRGRGRCEDGECICDAGYSGDDCGVRSCPGDCNQRGH-CE--------DGRCVCWPGYTGADCSTRACPRDCR--GRGRCE-DGVCVCHAGYSGEDCGV---------RSCPGDCRGRGNCESGRCVC-WPGY----TGRDCGTR--ACPGDCRGRGRCVDGRCVCNPGFTGEDC-----------GSRRCPGDCRG-HGHCENGVCVCAVGY--SGDDCSTRSCPSDCRGRGQCLNGLCECDEGYSGEDCGIRRCPRDCSQHGVCQD-GLCMCHAGYAGEDCSIRTCPADCRRRGRCEDGRCVCNPGYTGPAC 634 HSP 4 Score: 67.0106 bits (162), Expect = 1.503e-10 Identity = 39/117 (33.33%), Postives = 51/117 (43.59%), Query Frame = 1
Query: 778 AIDNCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQM 1128
A C DC G CV+ C C G+ GE C EP C GC + C+C +C ++TC C++ G C QGRC C EG+ GD C EI + +M
Sbjct: 635 ATRTCPADCRGRGRCVQGVCMCYVGYSGEDCGQEEPPASA------CPGGCGPRELCRAGQCVCVEGFRGPDC-AIQTCPGDCRSRGECIQGRCVCQEGYAGDDCGEEIPAIQNMRM 744
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|Q07008|NOTC1_RAT (Neurogenic locus notch homolog protein 1 OS=Rattus norvegicus OX=10116 GN=Notch1 PE=1 SV=3) HSP 1 Score: 217.238 bits (552), Expect = 4.539e-56 Identity = 231/772 (29.92%), Postives = 328/772 (42.49%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-DCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC-DKDK---CKCPPGYIGHNCEFNDFCHFISPCEH-NCTTINDNMVCSCLPGYD-LMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
C C GW GE C E C G + R F C C T C C S C G C + C C G+ G C +++ C+ +G CEH C+N +F+C+C G+ + + D CI C T ++ C C G++G +C + DEC C CV+ I + C C +GF+ C + KNG CL+G C C G+ G C +DIDEC + LC + +F C C G+T + N +C S+ C +GG C D+D C C G G NCE N +PC+ C D C+C PGY M + + P GTC + C+CP+G+ C +++NEC + C + + + C C G + C+ N TC KD G C C+ G+ G C +INEC + + C++ YKC+C L +C+ V + C C + CK C TGW G+ C++DI+EC+ + + +C N+NGSY C C + GR+C D C +PC NGG C + + C C PG+ G CEEDINEC ++G C + +Y C CP G+ + C+ +T D C NGG C D C CP GF G C DV+EC PC G C ++YG++ C C Y +
Sbjct: 321 CVCVNGWTGEDCS----ENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECA---LGANPCEHAGKCLNT-LGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGRCVDKINEFLCQCPKGFSGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGLCKDGVATFTCLCQPGYTGHHCETNINECHSQPCR----HGGTCQDRDNYYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCV--NGGTC--KDMTSGYV----CTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCP----LPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSPCRHGASCQNTNGSYRCLCQAGYT-----GRNCESDIDDCRPNPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINECASNPCQNG--ANCTDCVDSYTCTCPTGFNGIH----CENNTPDCT-ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSR-PCLH-GGTCQDSYGTYKCTCPQGYTGL 1054 HSP 2 Score: 196.823 bits (499), Expect = 9.956e-50 Identity = 242/854 (28.34%), Postives = 354/854 (41.45%), Query Frame = 1
Query: 808 EHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKL-DFSCICGIKETQNNCLELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSR------------GQMGNRTCE-------------------------HICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL-------------------------------SNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDL---MPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSK-----CICKSGYRGKRCDEDINECKKYSHICEH-FCMNTEGSYKCSCMPGFILS---ANSHSCQ-SVC---SLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHN-CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
+HG V C C G+ G C+ C C +G + D L ++ C C + +C + C S C NGG C C C GF G C+ ++N CS+ ++G+ C C G+ +C C GF N + C C G V + NC+C W G++C +DVDEC L P CQ C N+ G Y C C G+T +G+ + C N CN+ +C +NG IC C SG+ G CS D+DEC + CEH C+N GSF CQC G+T +I+ +CIS C + + +C C PGY G CE N SPC HN C + +C C G+ D C C KC+ G N C C +G+ G CE DI+EC +C + + +F C C+ G+ + N C + C HG + C+C G G C+ ++++C S+ C+ C++ Y+C+C PG+ S N C S C C++G F C+C G+ C +++EC N + C H C + Y C C P + G +C N+ C S+PC NGG C + C C+ G++G +C+ +INEC + + C+ G C + Y+C CP Y TC++ +P C N GVC++ C CP G+ G C +D++EC + +PC + C NT GS+ C C + Y
Sbjct: 78 DHGGIVDYACSCPLGFSGPLCLTPLANACLANP---CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNSHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGRCVDKINEFLCQCPKGFSGHLCQYDVDECASTPCKNGAKCLDGP-NTYTCVCTEGYTGTHCEVDIDECDPDPCHYGLCKDGVATFTCLCQPGYTGHHCET-----NINECHSQPCRHGGTCQDRDNYYLCLCLKGTTGPNCEINLDDCA--SNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFT--CRCPEGYHDPTCLSEVNEC--NSNPCIHGACRDGLNGYKCDC-APGW----SGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINEC----ASNPCLNQGTCIDDVAGYKCNCPLPYT----GATCEVVLAPCATSP-CKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVK-SPC-RHGASCQNTNGSYRCLCQAGYT 900 HSP 3 Score: 172.555 bits (436), Expect = 4.021e-42 Identity = 229/836 (27.39%), Postives = 335/836 (40.07%), Query Frame = 1
Query: 781 IDNCVPDCGEHGIC----VKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG--------------------------------------CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT-TEVVSGN-CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLS----NGKCAINCLNN---CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF------ILS-----ANSHSCQSVCSLCKNGK--CDFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHG----CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR-----CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICY---NTYGSFYCQCSSNY 2958
ID C PD +G+C C C+ G+ G C E Q C HG + R + C+C T NC + L C+ C NGGTC G C+C EG+ C E+N C+ + C H +G N ++C C G+ N + C C GT ++ SG C C++G+ G C +++EC C Q C++ + Y+C+C +T + CA + N C ++ D + C C +GW G+ C +DI+EC + HG C N GS+ C C +G+T + N + I C NGG C + C C PG+ G CE + +PC++ NCT D+ C+C G++ + PD CV G N C CP GF G C+ D+NEC D R C+ + TC D + KC C GY G C + C C T Y C C G+ +LS A V LC++G D +K C C+ G+TG C+ ++DEC N + C + G +SC C ++ G +C E+ + C S PC+NGG C++ KC C G G CE ++++C P+ C G C + G Y C CPPG++ + C+ + + NP C G + R C C G G C ++ C R PC + G+C NT F C+C + +
Sbjct: 567 IDECDPDPCHYGLCKDGVATFTCLCQPGYTGHHCETNINECHSQP----CRHGGTCQDRDNYYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECN-----SNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSPCRHGAS--CQNTNGSYRCLCQAGYTGR-NCESDIDDCRPNPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCPTGFNGIHCENNTPDCTESSCFNGGTCVDGI-NSFTCLCPPGFTGSYCQYDVNEC-----------------------------DSRPCL--HGGTCQDSYGTY------KCTCPQGYTGLNCQNLVRWCDSAPCKNGGKCWQTNTQYHCECRSGWTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYH-----GSNCSEEINECLSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFV----GERCEGDVNECLSNP-CDPRGTQNCVQRVNDFHCECRAGHTGRRCESVINGC-RGKPC-RNGGVCAVASNTARGFICRCPAGF 1340 HSP 4 Score: 171.014 bits (432), Expect = 1.210e-41 Identity = 200/658 (30.40%), Postives = 284/658 (43.16%), Query Frame = 1
Query: 1183 CKCQSGF--QLDNDGKSCIKEECSKFGTTEVVSGN------CKCKQGWKGKFCNDDV-DECLFPVCQQ--IC-VNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCL----NGICYCFSGWHGEDCSLDIDECKYNHG-CEH--LCVNVPGSFNCQC---HSGFTLQINKKKCISKSCNIECLNGGLC-----DKDKCKCPPGYIGHNCEFN------DFCHFISPCEHNCTTINDNMVCSCLP---GYDLMPDKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQ-HVCTNTIGSFFCRCKNGHK--LAEDKRSCI--PPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHF--CMNTEGSYKCSCMPGFI-----LSAN---SHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C C F Q D C+ C GT VV C C G+ G C + + CL C+ C + T+ Y+C C G++ S + N C G CL + IC C G+HG C D++EC N G C H C N GS+ C C H+G ++ C C NGG C +C C PG+ G NCE N + C C T N C C P G D C+ + GTC+ + C C G+ G C +I++C + Q C + + SF+C C +G L +CI P N+ + D + V+G+ C C SGY G C +D++EC ++ CEH C+NT GS++C C+ G+ + N S+ CQ+ + C + +F +C C G+ G C+++ DEC C HN CV+ + C C F G C D C+S PCKNG KC++ C C GY G CE DI+EC P H G C++ + C+C PGY C+ + + P C +GG C+D C C G G +C +++D+C PCD G C + + C C Y
Sbjct: 46 CVCSGAFVGQRCQDPSPCLSTPCKNAGTCYVVDHGGIVDYACSCPLGFSGPLCLTPLANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQ----NGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYN----CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNSHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAI---CTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQND-ATCLDQIGEF--QCICMPGYEGVYCEINTDECA--SSPCLHNGRCVDKINEFLCQCPKGF-----SGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECD-PDPCH--YGLCKDGVATFTCLCQPGYT----GHHCETNINECHSQP-CRHGGTCQDRDNYYLCLCLKGTTGPNCEINLDDCASN-PCDS--GTCLDKIDGYECACEPGYT 671 HSP 5 Score: 150.599 bits (379), Expect = 2.806e-35 Identity = 208/738 (28.18%), Postives = 297/738 (40.24%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQT---------ICQH--VCTNTIGSFFCRCKNGHKLA--EDKRSCIPPNK----KTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQSVCSLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD--TMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGV 2859
C+HG D + C C + NC + C S C NGGTC C C EGF G CQ IN C+ + C+N+G ++C C +G + C C G + + S +C C GW+G+ C D++EC+ C+ C NT GSY+C C+ G+T + +C N C+ G C +G+ C C G+ G C DI+EC N C++ C + S+ C C +GF + N C SC NGG C + C CPPG+ G C+++ PC H C C+C GY + + + + C G T + C+C G+ G C+ C +CQH +C + +C C+ G+ + ED+ PN TC D + F+ KC+ +GY G C E+INEC S C++ C++ +YKCSC G N C FNN C C G+ GE C+ D++ECL N + NCV + C C + GR C + C PC+NGG C + C+C G+ G +CE D C +G G C + + C+C L CQ NP C N G C S RC CP F+G+ C +
Sbjct: 725 CIHGACRDGLN-GYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINECASNP-CQNGANCTDCVDSYTCTCPTGFNGIHCENNTPDCTESSC----FNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGKCWQTNTQYHCECRSGWTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTD----YLGGFSCKCV--AGYHGSNCSEEINEC--LSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECR-----AGHTGRRCESVINGCRGKPCRNGGVCAVASNTARGFICRCPAGFEGATCENDARTCGSLRCLNG--GTCISGPRSPTCLC----LGSFTGPECQFPASSPCVGSNP-CYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1427 HSP 6 Score: 117.857 bits (294), Expect = 2.861e-25 Identity = 136/469 (29.00%), Postives = 196/469 (41.79%), Query Frame = 1
Query: 1672 CLNGGLCD----KDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDI------NECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHG-QC--FNSK--CICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQS-----VCSLCKNGKC-----DFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC---SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLV----LDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYA-PCDKLRGICYNTYGSFYCQCSSNYV 2961
CLNGG C+ + C C ++G C+ C +PC+ + TC ++ G + C CP GF+G LC + N C N C + T+ + CRC G +SC C C +G QC F S C C G+ G C +D+NEC + +C H C N GSY+C+C + C+ S C+NG D ++C C G+ G+ C+ ++D+C N K CV+ +Y+C C + G+ C E D C + C+NGG C NS C C G+ G+ C E+I++C G C + ++ C CP G L+D + + C+ + +NG + C CP G+ G C DVDEC A PC+ G C NT GSF CQC Y
Sbjct: 31 CLNGGRCEVANGTEACVCSGAFVGQRCQDPSPC-LSTPCK----------------------NAGTCYVVD-----HGGIVDYACSCPLGFSGPLCLTPLANACLANPCRNGGTCDLL---TLTEYKCRCPPGWS----GKSCQ--QADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACR----ATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWT-----GQYCTEDVDECQLMPNACQNGGTCHNSHGGYNCVCVNGWTGEDCSENIDDCASAACFQGAT--CHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNG-----KAICTCPSGYTGPACSQDVDECALGANPCEHA-GKCLNTLGSFECQCLQGYT 445 HSP 7 Score: 85.5001 bits (210), Expect = 2.048e-15 Identity = 132/520 (25.38%), Postives = 183/520 (35.19%), Query Frame = 1
Query: 802 CGEHGICVKSR------CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQ----------MGNRTC-------------------EHICVN-----EGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-------------------------------------------DCLNGI----------CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQC---HSGFTLQINKKKCIS----KSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCE----HNCTTINDNMVCSCLPGYDLMP--------DKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC 1968
C G+C +S C C TGW G+ C I E K C HG S + C+C T NC ++ C C NGG+C G C C GF+G C+ +IN C+ + + TC E C N +G N+F C C GF D C C GT + G C C QG+ G C + V C C+ C T Y C CR G+T + +++C K G C NG C C +G+HG +CS +I+EC + C++ C+++ ++ C C G +IN C S + +C N G C C CPPG++G CE + +PC+ NC ++ C C G+ K C+ T C+CP GF G CEND C
Sbjct: 838 CKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSP----CRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCPTGFNGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGKCWQTNTQYHCECRSGWTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINEC-LSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGHTGRRCESVINGCRGKPCRNGGVCAVASNTARGFICRCPAGFEGATCENDARTC 1352
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|P46531|NOTC1_HUMAN (Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4) HSP 1 Score: 216.853 bits (551), Expect = 5.487e-56 Identity = 232/772 (30.05%), Postives = 325/772 (42.10%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-DCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC-DKDK---CKCPPGYIGHNCEFNDFCHFISPCEH-NCTTINDNMVCSCLPGYDLMP---DKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C C GW GE C E C HG + R F C C T C C S C G C + C C G+ G C +++ CS +G CEH C+N +F+C+C G+ + + D C+ C T ++ C C G++G C + DEC C C++ I +QC C GFT C + KNG CL+G C C G+ G C +DIDEC + C + +F C C G+T + N +C S+ C +GG C D+D C C G G NCE N SPC+ C D C+C PGY + C C GTC + C+CP+G+ C +++NEC + C +++ + C C G + C+ N TC KD G C C+ G+ G C +INEC + + C++ YKC+C+ L +C+ V + C C +C+ C TGW G+ C+VDI+EC+L+ + +C N++G Y C C + GR+C D C +PC NGG C + + C C PG+ G CEEDINEC ++G C + +Y C CP G+ + C+ +T D C NGG C D C CP GF G C DV+EC PC G C + GS+ C C Y
Sbjct: 321 CVCVNGWTGEDCS----ENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECS---LGANPCEHAGKCINT-LGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCR----HGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHN--GGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCV--NGGTC--KDMTSGYV----CTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL----LPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGY-----SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNG--ANCTDCVDSYTCTCPAGFSGIH----CENNTPDCT-ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQ-PCLH-GGTCQDGCGSYRCTCPQGYT 1052 HSP 2 Score: 187.193 bits (474), Expect = 1.252e-46 Identity = 234/832 (28.12%), Postives = 337/832 (40.50%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTC-----FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL-------------------------------SNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE---DKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN--------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFY----LSTVD----------------------------GRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C+C + G C E C Q+ L C HG + + C+C T NC CS CQNGGTC C C GF G C+ I+ C GN CK +G +C+ V + NC+C W G++C +DVDEC L P CQ C NT G Y C C G+T +G+ + C N CN+ +C +NG IC C SG+ G CS D+DEC + CEH C+N GSF CQC G+T +I+ +C+S C + + +C C PGY G +CE N SPC HN ++ NE +C+CP GF G LC+ D++EC + T C++ C + ++ C C G+ D C P C +G C + C+C+ GY G C+ +INEC S C H C + + +Y C C+ G +C+ C + CD +C C+ G+TG +C+++IDEC N C + ++C C ++ LS V+ G +C N+ C S+PC NGG C + C C+ G++G +C+ +INEC + + C+ G C + Y+C C L+ TC++ +P C NGG CR C CP G+ G C VD++EC +PC + C NT+G + C C + Y
Sbjct: 164 CHCPPSFHGPTCRQDVNE-CGQKPGL-CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCP----GN---------------NCK---------NGGACVDG---------VNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLD-------------------------------KINEFQCECPTGFTGHLCQYDVDECAS-TPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP--------DPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECS--SQPCRHGGTCQDRDNAYLCFCLKG----TTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINEC----ASNPCLNQGTCIDDVAGYKCNC----LLPYTGATCEVVLAPCAPSP-CRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINEC-VLSPC-RHGASCQNTHGGYRCHCQAGY 899 HSP 3 Score: 169.088 bits (427), Expect = 4.605e-41 Identity = 227/840 (27.02%), Postives = 329/840 (39.17%), Query Frame = 1
Query: 1024 CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ-------LDNDGKSCIKEECSKFGTTEVVSGN---CKCKQGWKGKFCNDDVDECLF--------------------------PVCQQ----------------ICVNTIGSYQCSCRE---------------------GFTLLSNGKCAINCL-------------------NNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK-YNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCEH--NCTT--INDNMVCSCLPGYDLMP---DKKTCKKLECP-----KCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVH-GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF--------ILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSC-------NLPFYL-----STVDGRSCLEKNDS---------------------CSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKP 3015
C NGG C C C F G +CQ + N C N H+ G ++ C C GF LDN +C+ C GT ++++ C+C GW GK C D C P C+Q C N +GSY+C CR G T G C NNC G C++G+ C C W G+ C+ D+DEC+ + C++ C N G +NC C +G+T + + + I + C +G C C+CP G G C ND C +PC NC T +N +C+C GY D C P KC+ T +C+C +G+ G CE D+NEC++ CQ+ C + IG F C C G++ + N C C+H G+C + +C C +G+ G C D++EC C++ +Y C C G+ I + C CK+G F C C+ G+TG C+ +I+EC + C+H C + + +Y C C N L S D +CL+K D +PC NGG C + C+C GY+ +C ++NEC H G CR++ Y+C C PG+ C I+ + NP C+NGG C+DM+ C C GF G +C +++EC PC +G C + + C C +L Y G +C E VL P
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDN---ACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGE-DCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDAC-ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCIN-TLGSFECQCLQGYTGPRCEIDVNECVSNP-CQNDATCLDQIGEFQCICMPGYEGVHCEV-----NTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHY--GSCKDGVATFT--CLCRPGYTGHHCETNINEC--SSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVH---GACRDSLNGYKCDCDPGW----SGTNCDINNNECESNP-CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN-PCLN-QGTCIDDVAGYKCNC----LLPYTGATC----EVVLAP 832 HSP 4 Score: 166.007 bits (419), Expect = 4.048e-40 Identity = 223/804 (27.74%), Postives = 328/804 (40.80%), Query Frame = 1
Query: 781 IDNCVPDCGEHGIC----VKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNR-TCEHICVNEGENNFQCKCQSGFQLD---NDGKSCIKEECSKFGTTEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN-----GDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGF---TLQINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGT-----CNENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQ--------SVCSLCKNGK--CDFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHG----CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR-----CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICY---NTYGSFYCQCSSNY 2958
ID C PD +G C C C G+ G C E Q C HG + R + C C T NC + L C+ + GTC C C G+ G C + I+ C+ N TCE +G N F C+C G+ ++ C C + ++G C C GW G C+ + +EC C C + Y C+CREGF S C N +N C N G C++ + C C + G C + + C + +G E SF+C C +G+ T +++ +C+ C C N GG +C C GY G NCE + D C +PC + +CT + C CLPG+ ++ + C G + C CP GF+G+ CEN+ +C + C + I SF C C G + + + + CL C + +C C GY G C ++ C C T Y+C C G+ S SC+ V LC++G D N C+C+ G+TG C+ +DEC + + C + G YSC C ++ G +C E+ D C S PC+NGG C++ KC C G G CE ++++C P+ C G C + G Y C CPPG++ + C+ + + NP C G + R C C G G C ++ C + PC K G C NT F C+C + +
Sbjct: 567 IDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQP----CRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCE-----DGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGF---SGPNCQTN-INECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGY----RCHCQAGYSGRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYH-----GVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV----GERCEGDVNECLSNP-CDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGC-KGKPC-KNGGTCAVASNTARGFICKCPAGF 1340 HSP 5 Score: 155.992 bits (393), Expect = 6.432e-37 Identity = 213/739 (28.82%), Postives = 301/739 (40.73%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKC---QSGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQT---------ICQH--VCTNTIGSFFCRCKNGHKLA--ED-KRSCIPP---NKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQS-VCSLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDT-MCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGV 2859
CVHG D + C C + NC + C S C NGGTC C C EGF G CQ IN C+ + C+N+G ++C C +G + C C G + + S +C C GW+G+ C D++EC+ C+ C NT G Y+C C+ G++ + +C N C+ G C +GI C C G+ G C DI+EC + +G C + S+ C C +GF+ + N C SC NGG C + C CPPG+ G C+ + PC H T + + C+C GY + + C G T + +C+CP G+ GL C+ C +CQH +C + + CRC+ G+ + ED C P N TC D C C +GY G C E+I+EC SH C++ C++ +YKCSC G N C V + ++ KC FNN C C G+ GE C+ D++ECL N + NCV + C C + GR C + C PCKNGG C + CKC G+ G +CE D C +G G C + + C+C L CQ + C N G C S RC CP F+G+ C +
Sbjct: 725 CVHGACRDSLN-GYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGAN--CTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC----FNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDY------LGGYSCKCVAGYHGVNCSEEIDEC--LSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKC-FNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECR-----AGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNG--GTCISGPRSPTCLC----LGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1427 HSP 6 Score: 87.8113 bits (216), Expect = 4.706e-16 Identity = 102/351 (29.06%), Postives = 141/351 (40.17%), Query Frame = 1
Query: 2086 KTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECK----KYSHICEHFCMNTEGSYKCSCMPGFI----LSANSHSCQSVCSLCKN-GKCDF----NNKCKCKTGWTGE-------------------------------------LCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKC-----VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPP---GYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQC 2946
+TCL+ C+C + G RC +D N C K + C Y CSC GF L+ ++C + + C+N G CD KC+C GW+G+ C D++EC C+H C N GSY C C +T G +C CS SPC+NGG C V +C C PG+ G +CEE+I++C K+G G C + Y C CPP G +D CQ+ C NGG C + C C G+ G DC ++D+C A C C++ SFYC+C
Sbjct: 29 ETCLNGGKCEAANGTEACVCGGAFVGPRC-QDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNAC--LTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCR-----ATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNG--GACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPN------ACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAA-CFH-GATCHDRVASFYCEC 361 HSP 7 Score: 67.0106 bits (162), Expect = 9.888e-10 Identity = 63/205 (30.73%), Postives = 86/205 (41.95%), Query Frame = 1
Query: 2401 ECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC--------VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRN-------TFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
E LN KC+ +NG+ +C C F G C + N S+PCKN G C + C C G++G C P+ CRN T Y+C CPPG+ K+CQ + D + C NGG C C+CP FHG C DV+EC + + G C+N GS+ C C + +
Sbjct: 29 ETCLNGGKCE----AANGTEACVCGGAFV-----GPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT-------PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGW----SGKSCQQA--DPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHT 211
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|P46530|NOTC1_DANRE (Neurogenic locus notch homolog protein 1 OS=Danio rerio OX=7955 GN=notch1a PE=2 SV=1) HSP 1 Score: 214.927 bits (546), Expect = 2.270e-55 Identity = 241/774 (31.14%), Postives = 332/774 (42.89%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLF-PVCQQICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNNCNKNG-DCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFN-DFCHFISPCEHN-CTTINDNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHG-----QCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLC-----KNGKC-----DFNN-KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
C C GW G+ C E C HG + R F C C T C L+ S CQ G C + C C G+ G C +I+ CS +G CEH C+N + +FQCKC G++ + D C C T ++ +C C G++G FC + D+C P C++ I S+ C C +GF S C ++ C + KNG C +G C C G+ G C LDI+EC + +C + SF C C G+T ++ N +C+S+ C NGG C + C CP G G NCE N D C PC++ C + C C PGY + C C C+ G N C CP GF C + NEC + C + I S+ C C+ G R+C N CL CV+G C C++G+ G C +INEC + + C++ +KC+CM L C++V + C KNG DF + C C GW G+ C+VDI+EC+ N C N G + C CN F G C D C +PC NGG C + C C G+ G+ C EDI+EC ++G G C + +Y C CP G+ ++ C+I+T D C NGG C D C C GF G C DV+EC PC G C + YG++ C C Y +
Sbjct: 319 HCVCVNGWTGDDCS----ENIDDCASAACSHGATCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVSGKAICTCPPGYTGSACNQDIDECS---LGANPCEHGGRCLNT-KGSFQCKCLQGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICMPGYEGVFCQINSDDCASQPCLNGKCIDKINSFHCECPKGF---SGSLCQVDVDECASTPCKNGAKCTDGPNKYTCECTPGFSGIHCELDINECASSPCHYGVCRDGVASFTCDCRPGYTGRLCETNINECLSQPCR----NGGTCQDRENAYICTCPKGTTGVNCEINIDDCKR-KPCDYGKCIDKINGYECVCEPGYSGSMCNINIDDCALNPCHNGGTCIDGV-NSFTCLCPDGFRDATCLSQHNECSSNPCIHGSCLDQINSYRCVCEAGWM----GRNC-DININECLSNPCVNGGTCKDMTSGYLCTCRAGFSGPNCQMNINECASNPCLNQGSCIDDVAGFKCNCM----LPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQCRCNPGFT-----GALCENDIDDCEPNPCSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVSAPCRNG--GNCTDCVNSYTCSCPAGFSGIN----CEINTPDCT-ESSCFNGGTCVDGISSFSCVCLPGFTGNYCQHDVNECDSR-PCQN-GGSCQDGYGTYKCTCPHGYTGL 1052 HSP 2 Score: 187.578 bits (475), Expect = 7.949e-47 Identity = 246/878 (28.02%), Postives = 348/878 (39.64%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCL----ELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSC--SRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFT-------------------------------LLSNGKCAINCL-------------NNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYN-HGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN-CTTINDNMVCSCLPGYDL---MPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGH-----------------------KLAEDKRSCIPPNKKT----------CLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCS--LCKNGKC--DFNN-KCKCKTGWTGELCDVDIDECL-------------------------------LNQHKC-------QHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C C+ GW G+ C + +P C C +G + + C C C E C+NGGTC C+C + G CQ C S + G CV + C C GF +++ C + C G + + NC C + W G++C +DVDEC L P CQ C NTIG + C C G+T +G+ + C +NC+ N IC C G+ G C+ DIDEC + CEH C+N GSF C+C G+ +++ +C S C + CL+ GG C C PGY G C+ N PC + C ++ C C G+ D C C KC G N+ C+C GF+G+ CE DINEC + VC + + SF C C+ G+ + E+ C P T C K C +G+C + +C+C+ GY G C+ +I++C C++ S+ C C GF A S + CS C +G C N+ +C C+ GW G CD++I+ECL +N ++C Q +C++ + C+C LP+ G C CS PCKNGG C S+ C C G+ G +CE DINEC +G G C N G ++C C PG+ C+ D NP C NGGVC+D C C GF G C D+DEC APC + G C + S+ C C + +
Sbjct: 126 CRCQPGWSGKTCQLADP--CASNP---CANGGQCSAFESHYICTCPPNFHGQTCRQDVNECAVSPSPCRNGGTCINEVGSYLCRCPPEYTGPHCQRLYQPCLPSPCRSGG-----TCVQTSDTTHTCSCLPGFTGQTCEHNVDDCTQHACENGGPCIDGINTYNCHCDKHWTGQYCTEDVDECELSPNACQNGGTCHNTIGGFHCVCVNGWTGDDCSENIDDCASAACSHGATCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVSGKAICTCPPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCKCLQGYEGPRCEMDVNECKSNPCQNDATCLDQIGGF----HCICMPGYEGVFCQINSDDCASQPCLNGKCIDKINSFHCECPKGFSGSLCQVDVDECASTPCKNGAKCTDGP-NKYTCECTPGFSGIHCELDINECASSPCHYGVCRDGVASFTCDCRPGYTGRLCETNINECLSQPCRNGGTCQDRENAYICTCPKGTTGVNCEINIDDCKRKPCDYGKCIDKINGYECVCEPGYSGSMCNINIDDCALNPCHNGGTCIDGVNSFTCLCPDGF-RDATCLSQHNECSSNPCIHGSCLDQINSYRCVCEAGWMGRNCDININECLSNPCVNGGTCKDMTSGYLCTCRAGFSGPNCQMNINECASNPCLNQGSCIDDVAGFKCNCMLPYT-----GEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNG--GVCENLRGGFQCRCNPGFT----GALCENDIDDCEPNP-CSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVS-APC-RNGGNCTDCVNSYTCSCPAGF 973 HSP 3 Score: 171.4 bits (433), Expect = 1.047e-41 Identity = 229/794 (28.84%), Postives = 330/794 (41.56%), Query Frame = 1
Query: 781 IDNCVPD-CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG--------DCLNG-ICYCFSGWHGEDCSLDIDECK----YNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-TCNEN----KCKCPKGFAGLLCENDINEC---------LNQTICQHV--CTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQ-SVCSLCKNGKCDFNNK----------CKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCV---NSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDT-MCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGV 2859
ID+C + C G C+ C C G+ C+ E C+HG D+ + C+C NC + + C S C NGGTC C C GF G CQ+ IN C+ + C+N+G F+C C +G +N C C G + + S +C C GW+G+ C D++EC+ C +C N G +QC C GFT G N +++C N D +NG +C C +G+ GE C+ DIDEC N G CVN S+ C C +GF+ +IN C SC NGG C C C PG+ G+ C+ + PC++ +C C+C GY + + + + C G +C + C+C G+ G+ C+ C +C+H C + + CRC+ G+ + E C P N TC D C C GY G C ++INEC S C++ C++ +YKCSC G + C SV L +C FN C C G+ GE C+ D++ECL + +NCV + C C + G+ C + C +PCKNGG C N+K CKC+PGY+G SCE D C ++G C + + C+C PG+ CQ + NP C NGG C+ +S RC CP F+G+ C +
Sbjct: 677 IDDCALNPCHNGGTCIDGVNSFTCLCPDGFRDATCLSQHNECSSNP----CIHGSCLDQIN-SYRCVCEAGWMGRNCDININECLSNPCVNGGTCKDMTSGYLCTCRAGFSGPNCQMNINECA---------SNPCLNQGSCIDDVAGFKCNCMLPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQCRCNPGFT----GALCENDIDDCEPNPCSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVSAPCRNGGNCTDCVN---SYTCSCPAGFSGINCEINTPDCTESSC----FNGGTCVDGISSFSCVCLPGFTGNYCQHDVNECDSRPCQNGGSCQDGYGTYKCTCPHGYTGLNCQSLVRWCDSSPCKNGGSCWQQGASFTCQCASGWTGIYCDVPSVSCEVAARQQGVSVAVLCRHAGQCVDAGNTHLCRCQAGYTGSYCQEQVDECQPNPCQNGATCTDY------LGGYSCECVPGYHGMNCSKEINEC--LSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEIDIDDCSPSVDPLTGEPRC-FNGGRCVDRVGGYGCVCPAGFVGERCEGDVNECLSDPCDPSGSYNCVQLINDFRCECRTGYT-----GKRCETVFNGCKDTPCKNGGTCAVASNTKHGYICKCQPGYSGSSCEYDSQSCGSLRCRNG--ATCVSGHLSPRCLCAPGF----SGHECQTRMDSPCLVNP-CYNGGTCQPISDAPFYRCSCPANFNGLLCHI 1424 HSP 4 Score: 166.007 bits (419), Expect = 3.973e-40 Identity = 244/911 (26.78%), Postives = 360/911 (39.52%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAIN----CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKDK-----CKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYD-------LMP-------DKKTCKKLE--------CP-------------KCVRGTCNEN----------KCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCK---NGHKLAEDKRSCIPP---NKKTCLD----------------------KDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-----------------------LSANSHSCQ--------------------------SVCSLCKN-GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPI----SKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGG-----VCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICY---NTYGSFYCQCSSNYVLM---YDGTSCMTMK 2997
C C G+ G C I + Q C++G DK F C C + + C +++ C S C+NG C G C+CT GF G C+L+IN C+ + C + +G +F C C+ G+ + + C+ + C GT + C C +G G C ++D+C C C++ I Y+C C G+ S C IN LN C+ G C++G+ C C G+ C +EC N C++ S+ C C +G+ + IN +C+S C +NGG C KD C C G+ G NC+ N +PC + + I+D C+C+ Y L P + C++ E CP +CVR C +C+C GF G LCENDI++C N VC + + F C C G + AED C+ N C D DC CFN C+C G+ G C D+NEC C + G+YKC+C G+ S +CQ SV LC++ G+C D N C+C+ G+TG C +DEC N + C + G YSC C +P Y G +C ++ + C S PC+NGG C++ KC C G G CE DI++C + + C G C + G Y C+CP G++ + C+ + + +P +G + D RC C G+ G C + C + PC K G C NT + C+C Y YD SC +++
Sbjct: 474 HCICMPGYEGVFCQINSDDCASQP----CLNGKCIDKIN-SFHCECPKGFSGSLCQVDVDECASTPCKNGAKCTDGPNKYTCECTPGFSGIHCELDINECA-----SSPCHYGVCRDGVASFTCDCRPGYTGRLCETNINECLSQPCRNGGTCQDRENAYICTCPKGTTGVNCEINIDDCKRKPCDYGKCIDKINGYECVCEPGY---SGSMCNINIDDCALNPCHNGGTCIDGVNSFTCLCPDGFRDATCLSQHNECSSNPCIHGSCLDQINSYRCVCEAGWMGRNCDININECLSNPC----VNGGTC-KDMTSGYLCTCRAGFSGPNCQMNINECASNPCLNQGSCIDDVAGFKCNCMLPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVCENLRGGFQCRCNPGFTGALCENDIDDCEPNPCSNGGVCQDRVNGFVCVCLAGFRGERCAEDIDECVSAPCRNGGNCTDCVNSYTCSCPAGFSGINCEINTPDCTESSCFNGGTCVDGISSFSCVCLPGFTGNYCQHDVNECDSRPCQNGGSCQDGYGTYKCTCPHGYTGLNCQSLVRWCDSSPCKNGGSCWQQGASFTCQCASGWTGIYCDVPSVSCEVAARQQGVSVAVLCRHAGQCVDAGNTHLCRCQAGYTGSYCQEQVDECQPNPCQNGATCTDYLGGYSCEC-VPGY----HGMNCSKEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEIDIDDCSPSVDPLTGEPRCFNGGRCVDRVGGYGCVCPAGFV----GERCEGDVNECLSDPCDPSGSYNCVQLINDF-RCECRTGYTGKRCETVFNGC-KDTPC-KNGGTCAVASNTKHGYICKCQPGYSGSSCEYDSQSCGSLR 1354 HSP 5 Score: 162.925 bits (411), Expect = 3.896e-39 Identity = 210/733 (28.65%), Postives = 287/733 (39.15%), Query Frame = 1
Query: 1024 CQNGGTCF-----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKE---------ECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGS-YQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN-HGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCE--HNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNG---GKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCI-----------------------------------GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C+NGGTC C+C G+ G CQL S C E+++ C C F G++C ++ C GT EV S C+C + G C CL C+ CV T + + CSC GFT + +C + C G C++GI C+C W G+ C+ D+DEC+ + + C++ C N G F+C C +G+T N C S +C+ +G C C+CP G G C +D C +PC+ NC T + + K + C CP G+ G C DI+EC L C+H C NT GSF C+ C GY G RC+ D+NECK + C++ G + C CMPG+ NS C S C NGKC D N C+C G++G LC VD+DEC K C + Y+C C F G C L+ N+ SSPC G + C C+PGY G CE +INEC ++G G+C + YEC+C PGY C I+ D NP C NGG C D C CP GF C +EC PC + G C + S+ C C + ++
Sbjct: 110 CRNGGTCSLLTLDTFTCRCQPGWSGKTCQLADPCASNPCANGGQCSAF-----ESHYICTCPPNFH----GQTCRQDVNECAVSPSPCRNGGTCINEVGSYLCRCPPEYTGPHCQRLYQPCLPSPCRSGGTCVQTSDTTHTCSCLPGFTGQTCEHNVDDCTQHACENGGPCIDGINTYNCHCDKHWTGQYCTEDVDECELSPNACQNGGTCHNTIGGFHCVCVNGWTGDDCSENIDDCASAACS----HGATCHDRVASFFCECPHGRTGLLCHLDDAC-ISNPCQKGSNCDT-----------------NPVSGKAI--------------CTCPPGYTGSACNQDIDECSLGANPCEHGGRCLNTKGSFQCK--------------------------------------CLQGYEGPRCEMDVNECKSNPCQNDATCLDQIGGFHCICMPGYEGVFCQINSDDCAS--QPCLNGKCIDKINSFHCECPKGFSGSLCQVDVDECASTPCKNGAKCTDGPNKYTCECTPGF-----SGIHCELDINECASSPCHYGVCRDGVASFTCDCRPGYTGRLCETNINECLSQPCRNGGTCQDRENAYICTCPKGTTGVNCEINIDDCKRKPCDYGKCIDKINGYECVCEPGY----SGSMCNINIDDCALNP-CHNGGTCIDGVNSFTCLCPDGFRDATCLSQHNECSS-NPC--IHGSCLDQINSYRCVCEAGWM 744
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|Q01705|NOTC1_MOUSE (Neurogenic locus notch homolog protein 1 OS=Mus musculus OX=10090 GN=Notch1 PE=1 SV=3) HSP 1 Score: 213.772 bits (543), Expect = 5.195e-55 Identity = 231/772 (29.92%), Postives = 327/772 (42.36%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-DCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC-DKDK---CKCPPGYIGHNCEFNDFCHFISPCEH-NCTTINDNMVCSCLPGYD-LMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
C C GW GE C E C G + R F C C T C C S C G C + C C G+ G C +++ C+ +G CEH C+N +F+C+C G+ + + D CI C T ++ C C G++G +C + DEC C C++ I +QC C +GF C + KNG CL+G C C G+ G C +DIDEC + C + +F C C G+T + N +C S+ C +GG C D+D C C G G NCE N +PC+ C D C+C PGY M + + P GTC + C+CP+G+ C +++NEC + C + + + C C G + C+ N TC KD G C C+ G+ G C +INEC + + C++ YKC+C L +C+ V + C C + CK C TGW G+ C+VDI+EC+ + + +C N+NGSY C C + GR+C D C +PC NGG C + + C C PG+ G CEEDINEC ++G C + +Y C CP G+ + C+ +T D C NGG C D C CP GF G C DV+EC PC G C ++YG++ C C Y +
Sbjct: 321 CVCVNGWTGEDCS----ENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECA---LGANPCEHAGKCLNT-LGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGHCMDKINEFQCQCPKGFNGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCQPGYTGHHCETNINECHSQPCR----HGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCV--NGGTC--KDMTSGYV----CTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCP----LPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGASCQNTNGSYRCLCQAGYT-----GRNCESDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNPCQNG--ANCTDCVDSYTCTCPVGFNGIH----CENNTPDCT-ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSR-PCLH-GGTCQDSYGTYKCTCPQGYTGL 1054 HSP 2 Score: 196.438 bits (498), Expect = 1.512e-49 Identity = 243/883 (27.52%), Postives = 355/883 (40.20%), Query Frame = 1
Query: 808 EHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKL-DFSCICGIKETQNNCLELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSR------------GQMGNRTCE-------------------------HICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL-------------------------------SNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE---DKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN--------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFY----LSTVD----------------------------GRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
+HG V C C G+ G C+ C C +G + D L ++ C C + +C + C S C NGG C C+C GF G C+ ++N CS+ ++G+ C C G+ +C C GF N + C C G V + NC+C W G++C +DVDEC L P CQ C NT G Y C C G+T +G+ + C N CN+ +C +NG IC C SG+ G CS D+DEC + CEH C+N GSF CQC G+T +I+ +CIS C + + +C C PGY G CE N SPC HN ++ NE +C+CPKGF G LC+ D++EC + T C++ C + ++ C C G+ D C P C +G C + C+C+ GY G C+ +INEC +S C H C + + SY C C+ G +C+ C + CD +C C+ G+TG +C+V+IDEC + C + ++C C ++ LS V+ G +C N+ C S+PC NGG C + C C+ G++G +C+ +INEC + + C+ G C + Y+C CP Y TC++ +P C N GVC++ C CP G+ G C VD++EC + +PC + C NT GS+ C C + Y
Sbjct: 78 DHGGTVDYACSCPLGFSGPLCLTPLDNACLANP---CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFESSYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGHCMD-------------------------------KINEFQCQCPKGFNGHLCQYDVDECAS-TPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP--------DPCHYGSCKDGVATFTCLCQPGYTGHHCETNINEC--HSQPCRHGGTCQDRDNSYLCLCLKG----TTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINEC----ASNPCLNQGTCIDDVAGYKCNCPLPYT----GATCEVVLAPCATSP-CKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVK-SPC-RHGASCQNTNGSYRCLCQAGYT 900 HSP 3 Score: 175.252 bits (443), Expect = 6.646e-43 Identity = 210/716 (29.33%), Postives = 298/716 (41.62%), Query Frame = 1
Query: 1015 SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ-------LDNDGKSCIKEECSKFGTTEVVSGN---CKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCL----NGICYCFSGWHGEDCSLDIDECKYNHG-CEH--LCVNVPGSFNCQC---HSGFTLQINKKKCISKSCNIECLNGGLC-----DKDKCKCPPGYIGHNCEFN------DFCHFISPCEHNCTTINDNMVCSCLP---GYDLMPDKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQ-HVCTNTIGSFFCRCKNGHK--LAEDKRSCI--PPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHF--CMNTEGSYKCSCMPGFI-----LSAN---SHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCY---CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
S C NGG C C C+ F G +CQ + N C N H+ + G ++ C C GF LDN +C+ C GT ++++ C+C GW GK C D C N C G CL + IC C G+HG C D++EC N G C H C N GS+ C C H+G ++ C C NGG C +C C PG+ G NCE N + C C T N C C P G D C+ + GTC+ C C G+ G C +I++C + Q C + + SF+C C +G L +CI P N+ + D + V+G+ C C SGY G C +D++EC ++ CEH C+NT GS++C C+ G+ + N S+ CQ+ + C + +F +C C G+ G C+++ DEC C HN C++ + C C F +G C D C+S PCKNG KC++ C C GY G CE DI+EC P H G C++ + C+C PGY C+ + + P C +GG C+D Y C G G +C +++D+C PCD G C + + C C Y
Sbjct: 28 SGTCLNGGRCEVANGTEACVCSGAFVGQRCQ-DSNPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDN---ACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ-ADPCAS-----------------------------------NPCANGGQCLPFESSYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQ----NGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYN----CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAI---CTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQND-ATCLDQIGEF--QCICMPGYEGVYCEINTDECA--SSPCLHNGHCMDKINEFQCQCPKGF-----NGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECD-PDPCH--YGSCKDGVATFTCLCQPGYT----GHHCETNINECHSQP-CRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASN-PCDS--GTCLDKIDGYECACEPGYT 671 HSP 4 Score: 171.4 bits (433), Expect = 1.091e-41 Identity = 230/836 (27.51%), Postives = 334/836 (39.95%), Query Frame = 1
Query: 781 IDNCVPDCGEHGIC----VKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG--------------------------------------CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT-TEVVSGN-CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLS----NGKCAINCLNN---CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF------ILS-----ANSHSCQSVCSLCKNGK--CDFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHG----CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR-----CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICY---NTYGSFYCQCSSNY 2958
ID C PD +G C C C+ G+ G C E Q C HG + R + C+C T NC + L C+ C NGGTC G C+C EG+ C E+N C+ + C H +G N ++C C G+ N + C C GT ++ SG C C++G+ G C +++EC C Q C++ + Y+C+C +T + CA + N C ++ D + C C +GW G+ C +DI+EC + HG C N GS+ C C +G+T + N + I C NGG C + C C PG+ G CE + +PC++ NCT D+ C+C G++ + PD CV G N C CP GF G C+ D+NEC D R C+ + TC D + KC C GY G C + C C T Y C C G+ +LS A V LC++G D +K C C+ G+TG C+ ++DEC N + C + G +SC C ++ G +C E+ + C S PC+NGG C++ KC C G G CE ++++C P+ C G C + G Y C CPPG++ + C+ + + NP C G + R C C G G C ++ C R PC K G+C NT F C+C + +
Sbjct: 567 IDECDPDPCHYGSCKDGVATFTCLCQPGYTGHHCETNINECHSQP----CRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECN-----SNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGAS--CQNTNGSYRCLCQAGYTGR-NCESDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCPVGFNGIHCENNTPDCTESSCFNGGTCVDGI-NSFTCLCPPGFTGSYCQYDVNEC-----------------------------DSRPCL--HGGTCQDSYGTY------KCTCPQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQYHCECRSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYH-----GSNCSEEINECLSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFV----GERCEGDVNECLSNP-CDPRGTQNCVQRVNDFHCECRAGHTGRRCESVINGC-RGKPC-KNGGVCAVASNTARGFICRCPAGF 1340 HSP 5 Score: 150.599 bits (379), Expect = 2.469e-35 Identity = 210/738 (28.46%), Postives = 297/738 (40.24%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQT---------ICQH--VCTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQSVCSLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD--TMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGV 2859
C+HG D + C C + NC + C S C NGGTC C C EGF G CQ IN C+ + C+N+G ++C C +G + C C G + + S +C C GW+G+ C D++EC+ C+ C NT GSY+C C+ G+T + +C N C+ G C +GI C C G+ G C DI+EC N C++ C + S+ C C GF + N C SC NGG C + C CPPG+ G C+++ PC H C C+C GY + + + + C G T + C+C G+ G+ C+ C +CQH +C + +C C+ G+ + ++ C P N TC D + F+ KC+ +GY G C E+INEC S C++ C++ SYKCSC G N C FNN C C G+ GE C+ D++ECL N + NCV + C C + GR C + C PCKNGG C + C+C G+ G +CE D C +G G C + + C+C L CQ NP C N G C S RC CP F+G+ C +
Sbjct: 725 CIHGACRDGLN-GYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNP-CQNGANCTDCVDSYTCTCPVGFNGIHCENNTPDCTESSC----FNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQYHCECRSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTD----YLGGFSCKCV--AGYHGSNCSEEINEC--LSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECR-----AGHTGRRCESVINGCRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCENDARTCGSLRCLNG--GTCISGPRSPTCLC----LGSFTGPECQFPASSPCVGSNP-CYNQGTCEPTSENPFYRCLCPAKFNGLLCHI 1427 HSP 6 Score: 86.6557 bits (213), Expect = 9.977e-16 Identity = 116/444 (26.13%), Postives = 165/444 (37.16%), Query Frame = 1
Query: 784 DNCVPDCGEH-----GICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLEL-RTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQL-----EINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQC---HSGFTLQINKKKCIS----KSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCE----HNCTTINDNMVCSCLPGYDLMP--------DKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC 1968
+N PDC E G CV C C G+ G C E C R C+HG + + C C T NC L R C S C+NGG C+Q C+C G+ G C + E+ + RG C+H +CV+EG+ ++ C C+ G+ G +C D+VDEC CQ C + +G + C C +G+HG +CS +I+EC + C++ C+++ S+ C C G +IN C S + +C N G C C CPPG++G CE + +PC+ NC ++ C C G+ K CK T C+CP GF G CEND C
Sbjct: 981 ENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNE-CDSRP---CLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQYHCECRSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHY----------------------------------CHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKC---------------------------------VAGYHGSNCSEEINEC-LSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGHTGRRCESVINGCRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCENDARTC 1352
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|G3I6Z6|NOTC1_CRIGR (Neurogenic locus notch homolog protein 1 OS=Cricetulus griseus OX=10029 GN=NOTCH1 PE=1 SV=2) HSP 1 Score: 213.386 bits (542), Expect = 6.467e-55 Identity = 229/772 (29.66%), Postives = 327/772 (42.36%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-DCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC-DKDK---CKCPPGYIGHNCEFNDFCHFISPCEH-NCTTINDNMVCSCLPGYD-LMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
C C GW GE C E C G + R F C C T C C S C G C + C C G+ G C +++ C+ +G CEH C+N +F+C+C G+ + + D CI C T ++ C C G++G +C + DEC C C++ I + C C +GF+ C + KNG CL+G C C G+ G C +DIDEC + C + +F C C G+T + N +C S+ C +GG C D+D C C G G NCE N +PC+ C D C+C PGY M + + P GTC + C+CP+G+ C +++NEC + C + + + C C G + C+ N TC KD G C C+ G+ G C +INEC + + C++ YKC+C L +C+ V + C C + CK C TGW G+ C++DI+EC+ + + +C N+NGSY C C + GR+C D C +PC NGG C + + C C PG+ G CEEDINEC ++G C + +Y C CP G+ + C+ +T D C NGG C D C CP GF G C DV+EC PC G C ++YG++ C C Y +
Sbjct: 337 CVCVNGWTGEDCS----ENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECA---LGANPCEHAGKCLNT-LGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGHCMDKINEFLCQCPKGFSGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGFCKDGVATFTCLCQPGYTGHHCETNINECHSQPCR----HGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCV--NGGTC--KDMTSGYV----CTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNC----PLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSPCRHGASCQNTNGSYRCLCQAGYT-----GRNCESDIDDCRPNPCHNGGSCTDGINMAFCDCLPGFQGAFCEEDINECASNPCRNG--ANCTDCVDSYTCTCPAGFNGIH----CENNTPDCT-ESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSR-PCLH-GGTCQDSYGTYKCTCPQGYTGL 1070 HSP 2 Score: 197.208 bits (500), Expect = 9.119e-50 Identity = 242/857 (28.24%), Postives = 339/857 (39.56%), Query Frame = 1
Query: 808 EHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKL-DFSCICGIKETQNNCLELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSR------------GQMGNRTC-------------------------EHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL-------------------------------SNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH-FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK---------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI-GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKP 3015
EHG V C C G+ G C+ C C +G + D L ++ C C + +C + C S C NGG C C C GF G C+ ++N CS+ ++G+ C C G+ +C C GF N + C C G V + NC+C W G++C +DVDEC L P CQ C NT G Y C C G+T +G+ + C N CN+ +C +NG IC C SG+ G CS D+DEC + CEH C+N GSF CQC G+T +I+ +CIS C + + +C C PGY G CE N SPC HN ++ NE C+CPKGF+G LC+ D++EC + CKNG K CLD + C+C GY G C+ DI+EC C + FC + ++ C C PG+ H C++ + C + C C+ C G TG C++++D+C N C++ Y C+C P Y G C D C+ SPC NGG C + C+C GY+ +C ++NEC + + CI G CR+ Y+C C PG+ C I+ + NP C+NGG C+DM+ C C GF G +C +++EC PC +G C + + C C L Y G +C E VL P
Sbjct: 94 EHGGTVNYACSCPLGFSGPLCLTPLDNACLANP---CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCVCRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGHCMD-------------------------------KINEFLCQCPKGFSGHLCQYDVDECASTP----------------CKNGAK---------------CLDGPNTY------TCVCTEGYTGTHCEVDIDECDP--DPCHYGFCKDGVATFTCLCQPGYT----GHHCETNINECHSQPCRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPCD-SGTCLDKIDGYECACE-PGYT----GSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNEC----NSNPCIHGACRDGLNGYKCDCAPGW----SGTNCDINNNECESNP-CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASN-PCLN-QGTCIDDVAGYKCNCP----LPYTGATC----EVVLAP 848 HSP 3 Score: 172.94 bits (437), Expect = 3.354e-42 Identity = 211/716 (29.47%), Postives = 297/716 (41.48%), Query Frame = 1
Query: 1015 SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ-------LDNDGKSCIKEECSKFGTTEVVSGN---CKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCL----NGICYCFSGWHGEDCSLDIDECKYNHG-CEH--LCVNVPGSFNCQC---HSGFTLQINKKKCISKSCNIECLNGGLC-----DKDKCKCPPGYIGHNCEFN------DFCHFISPCEHNCTTINDNMVCSCLP---GYDLMPDKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQ-HVCTNTIGSFFCRCKNGHK--LAEDKRSCI--PPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHF--CMNTEGSYKCSCMPGFI-----LSAN---SHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCY---CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
S C NGG C C C+ F G +CQ + N C N H+ + G N+ C C GF LDN +C+ C GT ++++ C+C GW GK C D C N C G CL + IC C G+HG C D++EC N G C H C N GS+ C C H+G ++ C C NGG C +C C PG+ G NCE N + C C T N C C P G D C+ + GTC+ C C G+ G C +I++C + Q C + + SF+C C +G L +CI P N+ + D + V+G+ C C SGY G C +D++EC ++ CEH C+NT GS++C C+ G+ + N S+ CQ+ + C + +F +C C G+ G C+++ DEC C HN C++ + C C F G C D C+S PCKNG KC++ C C GY G CE DI+EC P H G C++ + C+C PGY C+ + + P C +GG C+D Y C G G +C +++D+C PCD G C + + C C Y
Sbjct: 44 SGTCLNGGRCEVANGTEACVCSGPFVGQRCQ-DPNPCLSTPCKNAGTCHVVEHGGTVNYACSCPLGFSGPLCLTPLDN---ACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ-ADPCAS-----------------------------------NPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCVCRATHTGPHCELPYVPCSPSPCQ----NGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYN----CRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAI---CTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQND-ATCLDQIGEF--QCICMPGYEGVYCEINTDECA--SSPCLHNGHCMDKINEFLCQCPKGF-----SGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECD-PDPCH--YGFCKDGVATFTCLCQPGYT----GHHCETNINECHSQP-CRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASN-PCDS--GTCLDKIDGYECACEPGYT 687 HSP 4 Score: 168.703 bits (426), Expect = 6.037e-41 Identity = 231/836 (27.63%), Postives = 335/836 (40.07%), Query Frame = 1
Query: 781 IDNCVPDCGEHGIC----VKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG--------------------------------------CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT-TEVVSGN-CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLS----NGKCAINCLNN---CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF------ILS-----ANSHSCQSVCSLCKNGK--CDFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQW---PISKHG-CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR-----CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICY---NTYGSFYCQCSSNY 2958
ID C PD +G C C C+ G+ G C E Q C HG + R + C+C T NC + L C+ C NGGTC G C+C EG+ C E+N C+ + C H +G N ++C C G+ N + C C GT ++ SG C C++G+ G C +++EC C Q C++ + Y+C+C +T + CA + N C ++ D + C C +GW G+ C +DI+EC + HG C N GS+ C C +G+T + N + I C NGG C + C C PG+ G CE + +PC + NCT D+ C+C G++ + PD CV G N C CP GF G C+ D+NEC D R C+ + TC D + KC C GY G C ++ C C T Y C C G+ +LS A V LC++G D +K C C+ G+TG C+ ++DEC N + C + G +SC C ++ G +C E+ + C S PC+NGG C++ KC C G G CE ++++C P S+ C G C + G Y C CPPG++ + C+ + + NP C G + R C C G G C ++ C R PC K G+C NT F C+C + +
Sbjct: 583 IDECDPDPCHYGFCKDGVATFTCLCQPGYTGHHCETNINECHSQP----CRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECN-----SNPCIHGACRDGLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSPCRHGAS--CQNTNGSYRCLCQAGYTGR-NCESDIDDCRPNPCHNGGSCTDGINMAFCDCLPGFQGAFCEEDINECASNPCRNGANCTDCVDSYTCTCPAGFNGIHCENNTPDCTESSCFNGGTCVDGI-NSFTCLCPPGFTGSYCQYDVNEC-----------------------------DSRPCL--HGGTCQDSYGTY------KCTCPQGYTGLNCQNLVHWCDSAPCKNGGKCWQTNTQYHCECRSGWTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYH-----GSNCSEEINECLSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCEINVDDCHPHLDPASRSPKCFNNGTCVDQVGGYSCTCPPGFV----GERCEGDINECLSNP-CDPRGTQDCVQRVNDFHCECRAGHTGRRCESVINGC-RGKPC-KNGGVCAVASNTARGFICRCPAGF 1356 HSP 5 Score: 147.902 bits (372), Expect = 1.561e-34 Identity = 210/739 (28.42%), Postives = 295/739 (39.92%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQT---------ICQH--VCTNTIGSFFCRCKNGHKLA--EDKRSCIPPNK----KTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSC---MPGFILSANSHSCQSVCSLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD--TMCNPHCLNGGVCRDMS-----RCYCPIGFHGIDCGV 2859
C+HG D + C C + NC + C S C NGGTC C C EGF G CQ IN C+ + C+N+G ++C C +G + C C G + + S +C C GW+G+ C D++EC+ C+ C NT GSY+C C+ G+T + +C N C+ G C +GI C C G+ G C DI+EC N +G C + S+ C C +GF + N C SC NGG C + C CPPG+ G C+++ PC H C C+C GY + + + C G T + C+C G+ G C+ C +CQH +C + +C C+ G+ + ED+ PN TC D + F+ KC+ +GY G C E+INEC S C++ C++ +YKCSC G N C FNN C C G+ GE C+ DI+ECL N + +CV + C C + GR C + C PCKNGG C + C+C G+ G +CE D C +G G C + + C+C L CQ NP C N G C S RC CP F+G+ C +
Sbjct: 741 CIHGACRDGLN-GYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGINMAFCDCLPGFQGAFCEEDINECASNPCRNGAN--CTDCVDSYTCTCPAGFNGIHCENNTPDCTESSC----FNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVHWCDSAPCKNGGKCWQTNTQYHCECRSGWTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTD----YLGGFSCKCV--AGYHGSNCSEEINEC--LSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCEINVDDCHPHLDPASRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDINECLSNPCDPRGTQDCVQRVNDFHCECR-----AGHTGRRCESVINGCRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCENDARTCGSLRCLNG--GTCISGPRSPTCLC----LGSFTGPECQFPASSPCVGSNP-CYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1443 HSP 6 Score: 116.316 bits (290), Expect = 8.921e-25 Identity = 152/551 (27.59%), Postives = 211/551 (38.29%), Query Frame = 1
Query: 1672 CLNGGLCD----KDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDI------NECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHG-QC--FNSK--CICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYK---------------------------------------CSCMPGFIL---SANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSC------------------------------NLPFYLSTVDGRSCL--EKNDSC-SSPCKNGGKC----VNSK--CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCS---SNYVLMYDGTSCMTM 2994
CLNGG C+ + C C ++G C+ + C +PC+ + TC +E G C CP GF+G LC + N C N C + T+ + CRC G +SC C C +G QC F S C C G+ G C +D+NEC + +C H C N GSY+ C+C+PGF N C + CKNG + C+C WTG+ C D+DEC L + CQ+ C N++G Y+C C FY GR+ L ND+C S+PC G C VN K C C GY G +C +D++EC + G+C NT G++EC C GY C+I + + NP C N C D +C C G+ G+ C ++ DEC +PC G C + F CQC S ++ YD C +
Sbjct: 47 CLNGGRCEVANGTEACVCSGPFVGQRCQDPNPC-LSTPCK----------------------NAGTCHVVE-----HGGTVNYACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLL---TLTEYKCRCPPGWS----GKSCQ--QADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCVCRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPG--NNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYT----GPRCEIDVNECISNP-CQNDATCLDQIGEFQCICMPGYEGVYCEINTDECAS-SPCLH-NGHCMDKINEFLCQCPKGFSGHLCQYDVDECAST 551 HSP 7 Score: 84.3445 bits (207), Expect = 5.370e-15 Identity = 132/520 (25.38%), Postives = 183/520 (35.19%), Query Frame = 1
Query: 802 CGEHGICVKSR------CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQ----------MGNRTC-------------------EHICVN-----EGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-------------------------------------------DCLNGI----------CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQC---HSGFTLQINKKKCIS----KSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCE----HNCTTINDNMVCSCLPGYDLMP--------DKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC 1968
C G+C +S C C TGW G+ C I E K C HG S + C+C T NC ++ C C NGG+C G C C GF+G C+ +IN C+ + + TC E C N +G N+F C C GF D C C GT + G C C QG+ G C + V C C+ C T Y C CR G+T + +++C K G C NG C C +G+HG +CS +I+EC + C++ C+++ ++ C C G +IN C S + +C N G C C CPPG++G CE + +PC+ +C ++ C C G+ K CK T C+CP GF G CEND C
Sbjct: 854 CKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSP----CRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGINMAFCDCLPGFQGAFCEEDINECASNPCRNGANCTDCVDSYTCTCPAGFNGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVHWCDSAPCKNGGKCWQTNTQYHCECRSGWTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINEC-LSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCEINVDDCHPHLDPASRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDINECLSNPCDPRGTQDCVQRVNDFHCECRAGHTGRRCESVINGCRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCENDARTC 1368
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A4D6G2V2 (Uncharacterized protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 472.626 bits (1215), Expect = 7.948e-157 Identity = 239/240 (99.58%), Postives = 239/240 (99.58%), Query Frame = 1
Query: 820 CVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDID 1539
CVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFS WHGEDCSLDID
Sbjct: 1 CVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSXWHGEDCSLDID 240 HSP 2 Score: 103.219 bits (256), Expect = 1.058e-20 Identity = 84/250 (33.60%), Postives = 126/250 (50.40%), Query Frame = 1
Query: 1690 CDKDKCKCPPGYIGHNCEF--NDFC--HFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLE-CPKCVR--GTCNENKCKCPKGFAGLLCENDINEC----LNQTICQHVCTNT-IGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLC-KNGKCDFNNKCKCKTGWTGELCDVDID 2400
C K +C C G+ G C + C + C H C+ + SC+ G + + C +L C K + GTC + +C+C +GF G C+ +IN C + C+H+C N +F C+C++G +L D +SCI + V G C CK G++GK C++D++EC +C+ C+NT GSY+CSC GF L +N + + C KNG C N C C + W GE C +DID
Sbjct: 1 CVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICG--IKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSG-----NCKCKQGWKGKFCNDDVDEC--LFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDC-LNGICYCFSXWHGEDCSLDID 240 HSP 3 Score: 98.9821 bits (245), Expect = 2.849e-19 Identity = 83/256 (32.42%), Postives = 128/256 (50.00%), Query Frame = 1
Query: 2122 CFNSKCICKSGYRGKRCDEDINE-CKKYSHI-CEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSL-CKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQ---HKCQHNCVNSN-GSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVD 2868
C S+C C++G+ G+RC E CK+ + C H C + SC+ G + N+ CS C+NG F +C+C G+ G+ C ++I+ C Q C+H CVN ++ C C F L DG+SC++ + CS + V+ CKCK G+ G C +D++EC +P+ + C+ NT G+Y+C C G+ +L + K + N CLNG CYC +HG DC +D+D
Sbjct: 1 CVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN-DGKSCIK--EECSKF--GTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICV----NTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG-------ICYCFSXWHGEDCSLDID 240 HSP 4 Score: 92.4337 bits (228), Expect = 5.691e-17 Identity = 66/177 (37.29%), Postives = 95/177 (53.67%), Query Frame = 1
Query: 2116 GQCFNSKCICKSGYRGKRCDEDINECKKY---SHICEHFCMNT-EGSYKCSCMPGFILSANSHSC-QSVCSLCKNGKCDF-NNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDIN 2628
G CF +C C G+ G +C +IN C + + CEH C+N E +++C C GF L + SC + CS K G + + CKCK GW G+ C+ D+DECL CQ CVN+ GSY CSC F L + +G+ + +C + C G C+N C C ++G+ C DI+
Sbjct: 73 GTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECS--KFGTTEVVSGNCKCKQGWKGKFCNDDVDECLF--PVCQQICVNTIGSYQCSCREGFTLLS-NGKCAI----NCLNNCNKNGDCLNGICYCFSXWHGEDCSLDID 240 HSP 5 Score: 80.4925 bits (197), Expect = 7.172e-13 Identity = 70/221 (31.67%), Postives = 103/221 (46.61%), Query Frame = 1
Query: 2344 NKCKCKTGWTGELCDVDIDECLLNQHK---CQHNCV--NSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQW-----PISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDG 2976
++C C+TGW GE C V ++ L Q K C H C +SC C + + +CLE +CS C+NGG C +C+C G+ GD C+ +IN C +H C+ E N N++C C G+ + +D K+C ++G C C G+ G C DVDEC + C + IC NT GS+ C C + L+ +G
Sbjct: 4 SRCYCETGWFGERC-VILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQN-----NCLELR-TCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGEN---NFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSG-------NCKCKQGWKGKFCNDDVDEC-LFPVCQQ---ICVNTIGSYQCSCREGFTLLSNG 203 HSP 6 Score: 64.6994 bits (156), Expect = 1.345e-7 Identity = 50/147 (34.01%), Postives = 69/147 (46.94%), Query Frame = 1
Query: 1444 CLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKY----NHGCEHLCVNV-PGSFNCQCHSGFTLQINKKKCISKSCN----IECLNGGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKK 1854
C C G C G C C G+ G+ C L+I+ C N CEH+CVN +F C+C SGF L + K CI + C+ E ++G CKC G+ G C + D C F C+ C + CSC G+ L+ + K
Sbjct: 65 CSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSG------NCKCKQGWKGKFCNDDVDECLF-PVCQQICVNTIGSYQCSCREGFTLLSNGK 204
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A0R3SU55 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS9006 PE=4 SV=2) HSP 1 Score: 422.55 bits (1085), Expect = 8.478e-122 Identity = 292/833 (35.05%), Postives = 424/833 (50.90%), Query Frame = 1
Query: 811 HGICVKSRCYCETGWFGERCVI----LEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNN--CLELRTCSKGCQNG-----GTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVV---------------SGNCKCKQGWKGKFCNDDVDECLFPV-----CQQICVNTIGSYQCSCREGFTLLSNGKCAINC-------LNNCNKN-----GDCLNGICYCFSGWHGEDCSLDIDECKYNHG----CEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNG-----GLCDKDKCKCPPGYIGHNCEFN-DFC----HFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPK------------CVRGTCNENKCKCPKGFAGLLCENDINECL----NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKT-CLD-KDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHI---CEHFCMNTEGSYKCSCMPGFILSANSHSCQS------VCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVN-SNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGNKGVT 3054
HG C+ RC C+ G+ G +C + E EL + C C + C G + + C ++ + ++ C++G G C +G C C GF G++C+ +IN C CE C+N ++ C C++G+ L +G SC +E + + V + C C+ G+ G C D+DEC + C+ C+NT GSY+C C G+ L NG N L +C N GDC+NG CYC G+ GE C D++EC+ G C+ CVN GSF C+C SG+ LQ + C + + EC +G G C +C C GY G NC+ + D C CE C + C C GY+L PD +C++ + C+ G C N C C +GFAG C+ DINEC+ +++ C+ +C NT GS+ C+C+ G++L + SC P + CL+ ++C +G+C + +CIC+SGY G +C+ DI+EC I CEH C+NT GSY+C C PG+ L ++ SCQ C NG CKC G+ G C+ +D C ++ C+H C N S+G Y C C + L++ DG++C + C+ PC N G C KC C G+ G SC+ED++EC P HGC CRNT+G+YECICP GY+++ +++TC C P C NGG+C+ + C CP GF G DC D+DEC + +PCD G C N G + C C Y+L+ DG C+ A PHL +RG G KG+T
Sbjct: 1219 HGDCLNGRCVCQQGFTGNQCEMDINECEGELGTYAR---CTQRCINTLGSYECECEPGYELGPDGYACFKVDSITE-CKDGVNCIHGVCSEGECICRSGFTGEKCERDINECLGENGIPPKCEQRCINI-PGSYDCGCEAGYVLQTNGYSCRRE---TYAPSRPVHNCREGFNCFYGRCSNDYCVCEPGFTGDQCERDIDECAGELGTKARCEHRCINTPGSYKCQCESGYILQPNGYSCRNSEPVLEWPLYDCRHNETCIYGDCVNGKCYCRPGFTGEMCDKDVNECEGEIGFVVRCQQRCVNTFGSFRCECESGYELQTDGFSCGKAASDPECKDGFNCIHGRCWNGQCVCLSGYTGENCDRDIDECIGDVGVQHQCEQQCINKPGSYYCQCYSGYELQPDGFSCRRADVANEWTGHHCQDGVNCIYGNCVNNDCICQQGFAGDRCDKDINECVGEMGSESRCEQICINTHGSYECQCEIGYELKSNGYSCRPSQSVSNCLEGENCFYGRCMDDRCICESGYTGSKCERDIDECSGELGIRVSCEHLCVNTHGSYECQCHPGYDLQSDGFSCQPGGGKNRYPGGCLNGGISLECGCKCPVGFRGSRCEEVVDICK-EKNPCEHICYNKSDGGYMCGCYDGYELNS-DGKTCGIPVE-CNPPCTNNGHCFRGKCICPSGFRGVSCDEDVDECAMPAVVHGCAHGCRNTYGSYECICPQGYILMTNKRTCTPVASSIECVPPCRNGGICQSNNICSCPRGFEGDDCSKDIDECTKLSPCDPEFGSCINRVGGYECICLPGYILLLDGKHCIEESRARQAPHLIFRGVGTKGIT 2040 HSP 2 Score: 334.724 bits (857), Expect = 4.646e-92 Identity = 256/723 (35.41%), Postives = 378/723 (52.28%), Query Frame = 1
Query: 973 IKETQNNCLEL-RTCSKGC-QNGGTCFQGR-CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLD-NDGKSCIKEECSKF---GTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV--CQQICVNTIGSYQCSCREGF--TLLSNGKCA-INCLNNCNK-NGDCLNGICYCFSGWHGEDCSLDIDEC-KYNHGCEHLCVNVPGSFNCQCHSGF-TLQINKKKCISKSCNIECLNG-GLCDKDKCKCPPGYIGHNCE--FNDFCHFISPCEHNCTTINDNMVCSCLPGYDL-MPDKKTCKKLEC-PKCV--RGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGHKLA-EDKRSCIPPNKKTCLDKDCVHGQC---FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGS-YKCSCMPGFILSANS------HSCQSVCSLCKNGKCDFNNK-CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNG-GKCVNSK-CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNT-FGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCR----DMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKP 3015
+ + QNN L RTC C Q+ G C +G C+C GF G C+ +++ C+ G G C H C+N +F+C C+ GF+LD + K+CI + C+ G + V G C+C +G++G FC DVDEC C+Q CVN GS+QC+C +G+ + +C ++C+ C + G C +GIC C G+ G C D+DEC + H CE CVN PGSF C C+ G+ L + ++C+ C+ C+ G G C D C C G+ G +CE ++ CEHNC + + C+C GY + + D K C+ + C P C+ +G C CKC +GF G C DINEC L C H+C N GS+ C C G+ L+ +D R+C+P + CL +CV G+ +CIC+ GY G C + + C H CEH C++ G + C C PG+I+ + C+ C + G CD+ +K C C++G+ G+ C+ +I+EC +N C H CV+++G+++C C L C+ + C PC +G G CV CKCK G++G CE + C ++ C EC + G +EC C PGY+ Q + T C C G C +C C G+ G +C DV+ECQ + C++ C NT GS+ C+C S Y L DG SC ++ V KP
Sbjct: 345 VLDPQNNRTCLGRTCEPACIQDQGECVEGGFCKCHPGFNGPSCESDVDECALGTSG---CNHDCINT-YGSFRCLCRPGFELDPRNNKTCIAKSCNPPCVPGQGDCVDGRCQCHEGFEGIFCERDVDECAERTHNCEQKCVNIYGSFQCACYDGYRPSPREPNRCERVDCVPPCVQGQGYCRDGICECVKGYSGRACERDVDECSEGRHDCEQKCVNTPGSFRCACYDGYRPLVSDARRCVPIRCDPSCVPGQGECQSDVCVCKEGFTGKSCEKDIDECLEGTHGCEHNCINTHGSYNCTCRDGYQVSLYDPKRCEPVRCDPDCIPGQGVCMNGVCKCHEGFTGESCAEDINECELRIDGCDHICINQFGSYECACNPGYDLSLKDSRTCVPGD---CL-ANCVPGKGDCDIYGRCICRPGYEGPYCQHEADVCSSGHHQCEHICVSLPGKKHLCRCYPGYIVDPKDPNRCIVYGCEPPCEI-GQGLCDYESKKCVCESGFMGDRCETNINECAVNNGGCSHICVDTHGAFTCDCPPGMQLVENSTFQCVTEEGYCDPPCYSGRGTCVRENYCKCKEGFSGQQCENIHDGC---LAFKPCEQECVSLEGGRFECRCFPGYIPS------QPNFFATRCVLECQEGKNCIHGQCSSGKCICKAGYTGENCDKDVNECQDRSRCEQR---CINTPGSYNCECESGYALQPDGYSCRRVEVPVEKP 1046 HSP 3 Score: 326.25 bits (835), Expect = 3.273e-89 Identity = 286/823 (34.75%), Postives = 398/823 (48.36%), Query Frame = 1
Query: 760 VCLNKPAIDNCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGC-SFDKRKLDFSCICGI---KETQNNCLELRTCSKGCQNG-GTC--FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL-DNDGKSCIKEE------CSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECL-FPVCQQICVNTIGS-YQCSCREGFTLLSNGKCAINCLNNCNK-----NGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIE-----------CLNGGLCDKDKCKCPPGYIGHNCEFN-DFCH----FISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKL---ECPK---CVRGTCNENKCKCPKGFAGLLCENDINECLNQT----ICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIP-PNKKTCLD-KDCVHGQCFNSKCICKSGYRGKRCDEDINECK----KYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSL--------CKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQ---HKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSP---CKNG-----GKCVNSKCKCKPGYNGDSCEEDINECQWPI-SKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTK-------DTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQ-RYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC 2985
C+ + NCVP G+ I RC C G+ G C E ++C C H C S +K C G + N C+ + C C+ G G C +C C GF GD+C+ IN C+ + N C HICV+ F C C G QL +N C+ EE C T V CKCK+G+ G+ C + D CL F C+Q CV+ G ++C C G+ A C+ C + +G C +G C C +G+ GE+C D++EC+ CE C+N PGS+NC+C SG+ LQ + C +E CLNG + +C C GY G CE + D C + CE C + C C G+ L PD +C+K+ EC C G C+E +C C GF G CE DI+EC +T C+ C N +GS+ C C G L D SC +C D +C HG C N +C+C+ G+ G +C+ DINEC+ Y+ C C+NT GSY+C C PG+ L + ++C V S+ C +G C +C C++G+TGE C+ DI+ECL KC+ C+N GSY C C + L T +G SC + + S P C+ G G+C N C C+PG+ GD CE DI+EC + +K C C NT G+Y+C C GY++ + +C+ S D N C+ G +CYC GF G C DV+EC+ + + C NT+GSF C+C S Y L DG SC
Sbjct: 729 TCVPGDCLANCVPGKGDCDI--YGRCICRPGYEGPYCQ-HEADVCSSGHHQ-CEHICVSLPGKKHLCRCYPGYIVDPKDPNRCI-VYGCEPPCEIGQGLCDYESKKCVCESGFMGDRCETNINECA---VNNGGCSHICVDT-HGAFTCDCPPGMQLVENSTFQCVTEEGYCDPPCYSGRGTCVRENYCKCKEGFSGQQCENIHDGCLAFKPCEQECVSLEGGRFECRCFPGYIPSQPNFFATRCVLECQEGKNCIHGQCSSGKCICKAGYTGENCDKDVNECQDRSRCEQRCINTPGSYNCECESGYALQPDGYSCRRVEVPVEKPPKYCTEGVDCLNGKFLNG-QCICKSGYAGECCERDIDECTGEAGSRAQCEQICINTRGSYECQCESGFQLQPDGYSCRKIGLSECKDGVNCFHGCCSEGECICRSGFTGDQCERDIDECSGETGIRPRCEQRCINILGSYECDCDPGFILQPDGFSCRRNETSSSCQDSSNCFHGDCLNGRCVCQQGFTGNQCEMDINECEGELGTYAR-CTQRCINTLGSYECECEPGYELGPDGYACFKVDSITECKDGVNCIHGVCS-EGECICRSGFTGEKCERDINECLGENGIPPKCEQRCINIPGSYDCGCEAGYVLQT-NGYSCRRETYAPSRPVHNCREGFNCFYGRCSNDYCVCEPGFTGDQCERDIDECAGELGTKARCEHRCINTPGSYKCQCESGYILQPNGYSCRNSEPVLEWPLYDCRHNETCIYGDCVN--GKCYCRPGFTGEMCDKDVNECEGEIGFVVRCQQRCVNTFGSFRCECESGYELQTDGFSC 1536 HSP 4 Score: 315.849 bits (808), Expect = 7.640e-86 Identity = 294/986 (29.82%), Postives = 438/986 (44.42%), Query Frame = 1
Query: 241 MNQVVKIFIIVL-INLEFYLIDSFNRNDYFKSGKNQKILSDRNRFFKFDLVQFPVDNNXXXXXXXXXXGYRNFVFTKRKIANSNFQSKNPPPTEYVWDEIGKYWTYKLRHHQSYPDFNFNEFPNSPCKPPFCLPRRCDQIDCGQ---SNCITNSRPCARNNQDCSMEQKRVLFGSEVVCLNKPAIDNCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGC---SFDKRKLDFSCICG---IKETQNNCLELRTCSKGCQNGGTCFQ--GRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV--CQQICVNTIGSYQCSCREGFTLLSNG-------KCAINCLNNCNKNGDCL-NGICYCFSGWHGEDCSLDIDECKY-NHGCEHLCVNVPGSFNCQCHSGFTLQI-NKKKCISKSCNIECLNG-GLCDKDKCKCPPGYIGHNCE--FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMP-DKKTCKKLEC-PKCVRGT--CNENKCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHK-LAEDKRSCIPPNKKTCLDKDCVHGQ--CFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSA-NSHSCQSVCSLCKNGKCD----------FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNG-GKC-VNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFG-NYECICPPGYLV-LDDQKTCQISTKDTMCNPHCLNG-GVC-RDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGN 3042
M ++++ ++ L + ++F L ++N +++ + + D D++ + + ++ + ++ PP + W+E G+YW Y Q P+ + + + C PP+C+P C Q G +C+T Q+C + C P C C+++ C C C I+ C+ +FC +GC + + CI +++ L++C C N GTC G C C GF G C L + + + CE+ C++ + C C L DG SC C G G C+ D+DECL + CQ C NT GSY+C C G L C C+ + G+C+ G C C G++G C D+DEC GC H C+N GSF C C GF L N K CI+KSCN C+ G G C +C+C G+ G CE ++ CE C I + C+C GY P + C++++C P CV+G C + C+C KG++G CE D++EC + C+ C NT GSF C C +G++ L D R C+P D CV GQ C + C+CK G+ GK C++DI+EC + +H CEH C+NT GSY C+C G+ +S + C+ V +CD N CKC G+TGE C DI+EC L C H C+N GSY C+CN + LS D R+C+ + C + C G G C + +C C+PGY G C+ + + C H C C + G + C C PGY+V D C + C P C G G+C + +C C GF G C +++EC IC +T+G+F C C L+ + T +E P Y GRG
Sbjct: 1 MTHLLQVILLFLQVTIQFAL--AWNNTSHYEVARLIEQHGDHQE--DVDVIDLRPPSQDDKFSNNYLESLDPDESSIHEVQEYSPSARLPPGVQ--WNEEGQYWGY-----QRVPNID-GSWSVTGCIPPYCIPALCSQGGPGSLCPQSCVT---------QNCDI--------------------GCFPYCIGGSQCIRNVCRCNAFIHQSNCNIIPSLDCRNFFGIFCANGCFKPTSVASPPECDCIIPYYVLRQPMCATETLQSCPNNCSNHGTCDHKVGECICDTGFTGPDCSLIDHCVNNPDL--PPCEYGCISLNDTRL-CTCPDNLVLQPDGVSCDN----------------PCPPGLTGPQCSYDIDECLTGIHECQYFCKNTFGSYECQCLPGMVLDPQNNRTCLGRTCEPACIQD---QGECVEGGFCKCHPGFNGPSCESDVDECALGTSGCNHDCINTYGSFRCLCRPGFELDPRNNKTCIAKSCNPPCVPGQGDCVDGRCQCHEGFEGIFCERDVDECAERTHNCEQKCVNIYGSFQCACYDGYRPSPREPNRCERVDCVPPCVQGQGYCRDGICECVKGYSGRACERDVDECSEGRHDCEQKCVNTPGSFRCACYDGYRPLVSDARRCVPIR----CDPSCVPGQGECQSDVCVCKEGFTGKSCEKDIDECLEGTHGCEHNCINTHGSYNCTCRDGYQVSLYDPKRCEPV-------RCDPDCIPGQGVCMNGVCKCHEGFTGESCAEDINECELRIDGCDHICINQFGSYECACNPGYDLSLKDSRTCVPGD--CLANCVPGKGDCDIYGRCICRPGYEGPYCQHEADVCSS--GHHQCEHICVSLPGKKHLCRCYPGYIVDPKDPNRCIVYG----CEPPCEIGQGLCDYESKKCVCESGFMGDRCETNINECAVNN--GGCSHICVDTHGAFTCDCPPGMQLVENSTFQCVTEEGYCDPPC-YSGRGT 901
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A0V0J366 (Uncharacterized protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR156685 PE=4 SV=1) HSP 1 Score: 388.267 bits (996), Expect = 8.964e-118 Identity = 270/716 (37.71%), Postives = 382/716 (53.35%), Query Frame = 1
Query: 1027 QNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLD-NDGKSCIKEECSKF---GTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV--CQQICVNTIGSYQCSCREGFTLLSNG--KCA-INCLNNC-NKNGDCLN-GICYCFSGWHGEDCSLDIDECKYN-HGCEHLCVNVPGSFNCQCHSGFTLQI-NKKKCISKSCNIECLNG-GLCDKD--KCKCPPGYIGHNCEFN-DFCHFI-SPCEHNCTTINDNMVCSCLPGYDLMPDK-KTCKKLEC--PKCV--RGTCNENKC-KCPKGFAGLLCENDINECLNQTICQHVCTNTIGS-FFCRCKNGHKLAEDK------RSCIPPNKKTCLDKDCVHGQCFNSK-----CICKSGYRGKRCDEDINEC---KKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNS-NGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGNKGVT 3054
Q G C GRC C GF G C+L+++ C + C+ CVN +F+C+C G+ LD D ++C+++ C G E G C+C+ G+ G C D+DEC C QIC+NT G+Y+C C+ G+ ++G +C ++C ++C +G+C + G C C G+ G C L++D C H CEH+CV+ G++ C+CH GF + +C+ C EC+ G G+C+ +CKC PG+ G C+ N D C C H C + C C PG+ L P+ + C+ + P CV +GTC + C KC G+ G+ CE N C CQ C N G + C C G A RSC+P ++C+HG+C S+ C CK G+RG +CDED+NEC +K +C+ C NT GS++CSC PG++L ++ SC K + +F++ + GE D C Q C+ C N+ +G Y C+C F L+ DG +C CS PC +G +C+ +C C PGY G C+ DI+EC P+S HGC C N G+Y+CICP GYL+L D+KTC + D C C NGG+C + C C GF G DC +D+DECQRY PCD G+C N YG F C+C YVL+ DG C+ A PHL YRG+G KGV
Sbjct: 4 QGQGECQNGRCVCRRGFSGRDCELDVDEC---REQPNICDQRCVNS-FGSFRCECDPGYNLDPRDNRTCVRDTCFDTCVQGQGECCKGICQCRPGFTGINCELDIDECQLGTHKCDQICINTRGAYRCECQPGYEFSTSGAERCEHVDCHSHCVPGHGECNDSGECQCRPGYEGVWCDLEVDLCASGRHNCEHICVSSQGTYFCRCHEGFRPDPQDPSRCMPLGCPKECVPGQGICEPKTGQCKCKPGFQGDLCDLNVDECSLNNGGCSHKCVDTFGSFHCECPPGWRLAPNSTRICEMVGACNPPCVPGQGTCVDTGCCKCKDGYMGMSCEIIYNACKALKPCQQRCINLGGGNYECSCWKGFVPAVHGNASKCIRSCVP-------GENCIHGKCVASRGRAPFCWCKPGFRGSQCDEDVNECLEGEKGRGLCQQQCTNTFGSFRCSCGPGYMLQSDGVSCL------KESESEFDDGVR-----PGEW-----DACKEKQ-PCEQLCFNTRDGEYQCACTEGFELN-ADGSTC-SSTKLCSPPCADGARCLQGRCLCPPGYGGPRCDADIDECSLPVSVHGCSFGCVNLPGSYKCICPAGYLLLVDKKTCIKPSHDADCQVSCQNGGICIGRNICRCLRGFTGKDCSLDIDECQRYRPCDPDYGLCINRYGGFDCECKPGYVLLVDGRHCIEEARARQAPHLVYRGKGTKGVV 689 HSP 2 Score: 262.307 bits (669), Expect = 1.769e-71 Identity = 238/711 (33.47%), Postives = 338/711 (47.54%), Query Frame = 1
Query: 811 HGICVKSRCYCETGWFGERCVI------LEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNG-GTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDG-KSCIKEECSKF---GTTEV-VSGNCKCKQGWKGKFCNDDVDECLFPV--CQQICVNTIGSYQCSCREGFT--LLSNGKC-AINCLNNC-NKNGDC--LNGICYCFSGWHGEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQCHSGFTLQINKKKC--ISKSCNIECLNG-GLC-DKDKCKCPPGYIGHNCE-FNDFCHFISPCEHNCTTI-NDNMVCSCLPGY--DLMPDKKTCKKLECP--KCVRGTCNENK-----CKCPKGFAGLLCENDINECL----NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNT-EGSYKCSCMPGFILSANSHSCQS--VCS-LCKNGKCDFNNKCKCKTGWTGELCDVDIDECLL--NQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEK--NDSCSSPCKNGGKCVNSK-CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGG 2796
G C RC C G+ G C + +P +C QR CV+ SF + + + N TC C G G C +G CQC GF G C+L+I+ C Q+G C+ IC+N ++C+CQ G++ G + C +C G E SG C+C+ G++G +C+ +VD C C+ ICV++ G+Y C C EGF +C + C C G C G C C G+ G+ C L++DEC N+ GC H CV+ GSF+C+C G+ L N + + +CN C+ G G C D CKC GY+G +CE + C + PC+ C + N CSC G+ + + C + P C+ G C ++ C C GF G C+ D+NECL + +CQ CTNT GSF C C G+ L D SC+ ++ D G R + + CK+ CE C NT +G Y+C+C GF L+A+ +C S +CS C +G +C C G+ G CD DIDEC L + H C CVN GSY C C YL VD ++C++ + C C+NGG C+ C+C G+ G C DI+ECQ G C N +G ++C C PGY++L D + C I PH + G
Sbjct: 6 QGECQNGRCVCRRGFSGRDCELDVDECREQPNICDQR----CVN--SFGSFRCECDPGYNLDPRDNRTCVRDTCFDTCVQGQGECCKGICQCRPGFTGINCELDIDEC---QLGTHKCDQICINT-RGAYRCECQPGYEFSTSGAERCEHVDCHSHCVPGHGECNDSGECQCRPGYEGVWCDLEVDLCASGRHNCEHICVSSQGTYFCRCHEGFRPDPQDPSRCMPLGCPKECVPGQGICEPKTGQCKCKPGFQGDLCDLNVDECSLNNGGCSHKCVDTFGSFHCECPPGWRLAPNSTRICEMVGACNPPCVPGQGTCVDTGCCKCKDGYMGMSCEIIYNACKALKPCQQRCINLGGGNYECSCWKGFVPAVHGNASKCIRSCVPGENCIHGKCVASRGRAPFCWCKPGFRGSQCDEDVNECLEGEKGRGLCQQQCTNTFGSFRCSCGPGYMLQSDGVSCLKESESEFDD-----------------GVR----PGEWDACKE-KQPCEQLCFNTRDGEYQCACTEGFELNADGSTCSSTKLCSPPCADGARCLQGRCLCPPGYGGPRCDADIDECSLPVSVHGCSFGCVNLPGSYKCICPA-GYLLLVDKKTCIKPSHDADCQVSCQNGGICIGRNICRCLRGFTGKDCSLDIDECQRYRPCDPDYGLCINRYGGFDCECKPGYVLLVDGRHC-IEEARARQAPHLVYRG 682 HSP 3 Score: 66.2402 bits (160), Expect = 3.575e-7 Identity = 59/177 (33.33%), Postives = 81/177 (45.76%), Query Frame = 1
Query: 790 CVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKL--DFSCICG----IKETQNNCLELR---TCSKGCQNGGTCFQGR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCE---HICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSG 1278
C P C + C++ RC C G+ G RC E L VHGCSF L + CIC + + C++ C CQNGG C GR C+C GF G C L+I+ C R R C+ +C+N F C+C+ G+ L DG+ CI+E ++ V G
Sbjct: 516 CSPPCADGARCLQGRCLCPPGYGGPRCDADIDEC----SLPVSVHGCSFGCVNLPGSYKCICPAGYLLLVDKKTCIKPSHDADCQVSCQNGGICI-GRNICRCLRGFTGKDCSLDIDECQR----YRPCDPDYGLCINR-YGGFDCECKPGYVLLVDGRHCIEEARARQAPHLVYRG 682
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A0R3T1B9 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS661 PE=4 SV=1) HSP 1 Score: 399.438 bits (1025), Expect = 6.549e-114 Identity = 270/747 (36.14%), Postives = 383/747 (51.27%), Query Frame = 1
Query: 1036 GTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEV--------------VSGNCKCKQGWKGKFCNDDVDECLFPV-----CQQICVNTIGSYQCSCREGFTLLSNGKCAINC-------LNNCNKN-----GDCLNGICYCFSGWHGEDCSLDIDECKYNHG----CEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNG-----GLCDKDKCKCPPGYIGHNCEFN-DFC----HFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPK------------CVRGTCNENKCKCPKGFAGLLCENDINECL----NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPP-NKKTCLD-KDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHI---CEHFCMNTEGSYKCSCMPGFILSANSHSCQ-----SVCSL-CKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVN-SNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGNKGVTK 3057
G C +G C C GF G++C+ +IN C CE C+N +++C C++G+ L DG SC EE S + +G C C+ G+ G C+ DVDEC+ + C+ C+NT GSY+C C G+ L +G L C ++ GDC+ C+C G+ GE C DIDEC+ G C+ CVN GS+ C C G+ LQ + C + + EC +G G C ++C C GY G NC+ + D C CE CT + C C GY+L D +C++ + C+ G C N C C +GFAG C+ DI+EC+ +++ C+ +C NT GS+ C+CK G++L + SC P N C ++C +G+C +CIC+SG+ G C+ DI+EC I CEH C+N GSY+C C PG+ L + SCQ + C + C NG N C+C G+ G C+ +D C ++ C+H C + S G Y C C + L++ DG++C + C+ C N +C KC C G+ G SCEEDI+EC P HGC CRNT+G+YECICP G +++ D++TC +T C C NGGVC + C CP GF G DC D+DEC +PCD G C N G + C C Y+L+ DG C+ A PHL +RG G KG+T+
Sbjct: 1301 GVCSEGECICKSGFTGERCERDINECLGENGFPPNCEQRCINT-PGSYECGCETGYVLQADGYSC--EEVSYAPSRPARDCRENFNCFYGQCSNGYCVCESGFTGDQCDRDVDECVGELGTVSRCEHRCINTPGSYECQCESGYILQPDGYSCRKSDPVLEWPLYKCQRDKTCIYGDCVKEKCHCRPGFTGERCDKDIDECEGELGFVSRCQQRCVNTFGSYRCDCEFGYELQTDGVSCRKTAPDTECKDGVNCIYGRCWNNQCICLSGYTGENCDRDIDECIGEAGVQHQCEQKCTNKPGSYDCQCYSGYELQSDGFSCRRADVVNEWTGYQCQSGVNCIYGNCVNNNCVCQQGFAGDRCDRDIDECVGEMGSESRCEQICINTPGSYECQCKTGYELMPNGYSCRPTQNALYCRQGENCFYGRCMGDRCICESGFTGDTCERDIDECSGEEGIRVGCEHLCVNFHGSYECQCYPGYKLQPDGFSCQPDGIENQCPIDCLNGGICLNYGCECPIGYRGPRCEEMVDICK-ERNPCEHFCYSKSEGGYMCGCKEGYELNS-DGKTCSVPIE-CNPLCANNAQCFRGKCICPRGFQGASCEEDIDECAMPAVVHGCAHGCRNTYGSYECICPQGNILMTDKRTCVEATSLVECTRPCRNGGVCHGNNICSCPRGFEGADCSKDIDECTTLSPCDPEFGSCINRVGGYECICLPGYILLLDGKHCIEESRARQAPHLVFRGVGTKGITR 2041 HSP 2 Score: 345.51 bits (885), Expect = 1.168e-95 Identity = 311/1018 (30.55%), Postives = 472/1018 (46.37%), Query Frame = 1
Query: 451 NFVFTKRKIANSNFQSKNPPPTEYV-----WDEIGKYWTYKLRHHQSYPDFNFNEFPNSPCKPPFCLPRRCDQ-----------------IDC-----GQSNCITNSRPCA--RNNQDCSMEQK---RVLFGS----------------------EVVCLNKP-----AIDNCVPDCGEHGIC--VKSRCYCETGWFGERCVILE-----PEL-----------------CKQRKLLF---------CVHGCSFDKRKLDF-SCICGIKETQNNC----------------LELR--------TCSKGC-QNGGTCFQGR-CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN-DGKSCIKEECSKF---GTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV--CQQICVNTIGSYQCSCREGF---TLLSNGKCAINCLNNC-NKNGDCLNGICYCFSGWHGEDCSLDIDEC-KYNHGCEHLCVNVPGSFNCQCHSGF-TLQINKKKCISKSCNIECL-NGGLCDKDKCKCPPGYIGHNCE--FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMP-DKKTCKKLEC-PKCVRG--TCNENKCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGHKLA-EDKRSCIP--------PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGS-YKCSCMPGFILSANS------HSCQSVCSLCKNGKCDFNNK-CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNG-GKCVNSK-CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNT-FGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCR----DMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKP 3015
N++ + + + + PP+ + W+E G+YW Y Q P+ + + + + C PP+C+P C Q + C G S CI N+ C R +C++ + FG L KP + +C +C HGIC C C+TG+ G C +++ P+L C +L C G + + D C+ GI E Q C L+ R TC C Q+ G C +G C+C GF+G +C+ +++ C+ G G C+H C+N +F+C C+ GF+LD+ D K+CI + CS G E + G C+C++G++G C D+DEC C+Q C+NT GS+QC+C + + T N ++C C + G C +G+C C G+ G C D+DEC + H CE CVN PGSF C C+ G+ L + ++C C+ C+ G C D C C G+ G +CE ++ CE NC + + +C+C GY + P D K C+++ C P CV+G C CKC +GF G C +DINEC L C H+C N +GS+ C C G++L+ D R+C+P P K C D HG +CIC+SGY G C +++ C H CEH C++ G + C C PG+I+ + C C + G C++ +K C C++G+ G+ C+++I+EC +N C H C++++G+++C C L+ C+ + C PC +G G CV CKC G++G CE ++ C ++ C EC + G +EC C PGY K Q + T C P C G C +C C G+ G +C DVDECQ + C+ C NT GS+ C+C S YVL DG SC + +V +P
Sbjct: 61 NYIESSYPDETNIHEIQEYPPSARLPPGVQWNEEGQYWGY-----QQVPNIDAS-WSATGCIPPYCIPALCSQGGPGSLCSQSCVTQNCEVGCFPYCIGGSQCIENTCRCNAFRKQSNCNLISPSDCQNFFGIFCSSGCFKPASAAPPSGCDCIIPYYVLRKPMCALETLQSCPKNCSNHGICDHKSGECICDTGYTGPDCSLIDHCINNPDLPPCEFGCISLNDTRLCTCPDNLVLQPDGVSCETPCPPGLTGPQCSYDIDECLTGIHECQYFCKNTFGSYECQCLPGMTLDPRNNRTCIGMTCEPACIQDQGECVEGGFCKCHPGFKGLRCESDVDECALGTSG---CDHDCINT-YGSFRCMCRPGFELDSRDNKTCIMKSCSPPCVPGQGECIDGRCQCREGFQGISCEGDIDECTDGTHDCEQKCINTHGSFQCACYDRYRPSTGHPNRCERVDCDPPCISGQGYCRDGVCECVKGYSGIACERDVDECSEGRHDCEQKCVNTPGSFRCACYGGYRPLASDPRRCEPIRCDPSCVPEQGECQNDVCVCREGFTGKSCEKDIDECLESTHACEQNCVNTHGSYICTCNEGYQVSPYDSKKCEQIRCDPDCVQGQGVCMNGVCKCYEGFTGETCADDINECELRIDGCDHICINQLGSYECACNPGYELSLNDSRACVPGDCLANCVPGKGDCDD----HG-----RCICRSGYEGPYCQHEVDVCSLGHHQCEHICVSLPGKRHLCRCYPGYIVDPKDPNQCIVYGCDPPCEI-GQGLCNYESKKCVCESGFRGDRCEININECAVNNGGCSHICLDTHGAFTCDCPPGMQLAENSTTQCVAEEGYCDPPCYSGRGTCVRENYCKCMEGFSGKQCENILDGC---LAFRPCEQECVSLDGGKFECRCFPGY------KPSQPNFFATRCVPECQEGRNCIHGQCSKGKCICKTGYTGENCDEDVDECQDRSLCEHH---CINTPGSYNCKCESGYVLQLDGHSCRRVDASVERP 1046 HSP 3 Score: 330.872 bits (847), Expect = 8.468e-91 Identity = 278/825 (33.70%), Postives = 398/825 (48.24%), Query Frame = 1
Query: 760 VCLNKPAIDNCVP---DCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGC-SFDKRKLDFSCICGI---KETQNNCLELRTCSKGCQNG-GTC--FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL-DNDGKSCIKEE------CSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECL-FPVCQQICVNTIGS-YQCSCREGFTLLSNGKCAINCLNNCNK-----NGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIE-----CLNG-----GLCDKDKCKCPPGYIGHNCEFNDFCHFISP------CEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPK------CVRGTCNENKCKCPKGFAGLLCENDINECLNQT----ICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNK-KTCLDK-DCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHI---CEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSL--------CKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQH---KCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKN--------GGKCVNSKCKCKPGYNGDSCEEDINECQWPI-SKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTK-------DTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQ-RYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC 2985
C+ + NCVP DC +HG RC C +G+ G C E ++C C H C S ++ C G + N C+ + C C+ G G C +C C GF GD+C++ IN C+ + N C HIC++ F C C G QL +N C+ EE C T V CKC +G+ GK C + +D CL F C+Q CV+ G ++C C G+ A C+ C + +G C G C C +G+ GE+C D+DEC+ CEH C+N PGS+NC+C SG+ LQ++ C ++E C++G G C +C C GY+G +CE D S CE C + C C G+ L PD +C+K+ P+ C G C+E +C C GF G CE DI+EC +T C+ C NT+GS+ C C +G L D SC C D +C +G C N C+C+ G+ G +C+ DINEC+ C C+NT GSY+C C PG+ L + ++C V L C +G C +C CK+G+TGE C+ DI+ECL C+ C+N+ GSY C C + L DG SC E + + S P ++ G+C N C C+ G+ GD C+ D++EC + + C C NT G+YEC C GY++ D +C+ S + C+ G ++ +C+C GF G C D+DEC+ + + C NT+GS+ C C Y L DG SC
Sbjct: 729 ACVPGDCLANCVPGKGDCDDHG-----RCICRSGYEGPYCQ-HEVDVCSLGHHQ-CEHICVSLPGKRHLCRCYPGYIVDPKDPNQCI-VYGCDPPCEIGQGLCNYESKKCVCESGFRGDRCEININECA---VNNGGCSHICLDT-HGAFTCDCPPGMQLAENSTTQCVAEEGYCDPPCYSGRGTCVRENYCKCMEGFSGKQCENILDGCLAFRPCEQECVSLDGGKFECRCFPGYKPSQPNFFATRCVPECQEGRNCIHGQCSKGKCICKTGYTGENCDEDVDECQDRSLCEHHCINTPGSYNCKCESGYVLQLDGHSCRRVDASVERPSRYCISGVNCFNGKCLNGRCTCQSGYMGESCE-RDINECTSEDGNRARCEQICVNTEGSYECQCESGFRLQPDGYSCQKIRAPECKDGENCFHGCCSEGECICRSGFTGDQCERDIDECSGETGIRPRCEQRCVNTLGSYRCDCDSGFILQPDGFSCRRNETFFNCQDGLNCFYGACLNGSCVCQQGFTGNKCELDINECEGELGTYAGCTQRCINTLGSYECKCEPGYELGPDGYACFKVDPLIECKDGVTCIHGVCS-EGECICKSGFTGERCERDINECLGENGFPPNCEQRCINTPGSYECGCETGYVLQ-ADGYSCEEVSYAPSRPARDCRENFNCFYGQCSNGYCVCESGFTGDQCDRDVDECVGELGTVSRCEHRCINTPGSYECQCESGYILQPDGYSCRKSDPVLEWPLYKCQRDKTCIYGDCVKE--KCHCRPGFTGERCDKDIDECEGELGFVSRCQQRCVNTFGSYRCDCEFGYELQTDGVSC 1536 HSP 4 Score: 285.034 bits (728), Expect = 1.307e-75 Identity = 263/808 (32.55%), Postives = 398/808 (49.26%), Query Frame = 1
Query: 787 NCVPDC-GEHGICVKSR-CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFD--KRKLDFSCIC----GIKETQNNCLELRTCSKGCQNG-GTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKS-CIKEECSK---FGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV--CQQICVNTIGSYQCSCREGFTLLSNG--KC-AINCLNNC-NKNGDCLNGICYCFSGWHGEDCSLDIDEC-KYNHGCEHLCVNVPGSFNCQCHSGFTLQ-INKKKCISKSCNIECLNG-GLCDKDKCKCPPGYIGHNC--EFNDFCHFISPCEHNCTTINDNMVCSCLPGYDL-MPDKKTCKKLEC-PKCV--RGTCNEN-KCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGS-FFCRCKNGHKL-AEDKRSCIPPNKKTCLDKDCVHGQCF----NSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHS-CQSVCSLCK------NGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGS-YSCSC------NLPFYLST------VDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQ-WPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTC-QISTKDTMCNPHCLNGGVCRDM----SRCYCPIGFHGIDCGVDVDECQR----YAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLK 3012
C P C + G CV+ C C G+ G RC E ++ + GC D F C+C + N +++CS C G G C GRCQC EGF+G C+ +I+ C+ G CE C+N +FQC C ++ + C + +C G G C+C +G+ G C DVDEC C+Q CVNT GS++C+C G+ L++ +C I C +C + G+C N +C C G+ G+ C DIDEC + H CE CVN GS+ C C+ G+ + + KKC C+ +C+ G G+C CKC G+ G C + N+ I C+H C + C+C PGY+L + D + C +C CV +G C+++ +C C G+ G C+++++ C L C+H+C + G CRC G+ + +D CI D C GQ + KC+C+SG+RG RC+ +INEC + C H C++T G++ C C PG L+ NS + C + C G C N CKC G++G+ C+ +D CL + C+ CV+ +G + C C + P + +T +GR+C+ G+C KC CK GY G++C+ED++ECQ + +H CI NT G+Y C C GY++ D +C ++ + +C++G C + RC C G+ G C D++EC A C++ IC NT GS+ CQC S + L DG SC ++ K
Sbjct: 358 TCEPACIQDQGECVEGGFCKCHPGFKGLRC---ESDV---DECALGTSGCDHDCINTYGSFRCMCRPGFELDSRDNKTCIMKSCSPPCVPGQGECIDGRCQCREGFQGISCEGDIDECTD---GTHDCEQKCINT-HGSFQCACYDRYRPSTGHPNRCERVDCDPPCISGQGYCRDGVCECVKGYSGIACERDVDECSEGRHDCEQKCVNTPGSFRCACYGGYRPLASDPRRCEPIRCDPSCVPEQGECQNDVCVCREGFTGKSCEKDIDECLESTHACEQNCVNTHGSYICTCNEGYQVSPYDSKKCEQIRCDPDCVQGQGVCMNGVCKCYEGFTGETCADDINECELRIDGCDHICINQLGSYECACNPGYELSLNDSRACVPGDCLANCVPGKGDCDDHGRCICRSGYEGPYCQHEVDVCSLGHHQCEHICVSLPGKRHLCRCYPGYIVDPKDPNQCIVYG----CDPPCEIGQGLCNYESKKCVCESGFRGDRCEININECAVNNGGCSHICLDTHGAFTCDCPPGMQLAENSTTQCVAEEGYCDPPCYSGRGTCVRENYCKCMEGFSGKQCENILDGCLAFR-PCEQECVSLDGGKFECRCFPGYKPSQPNFFATRCVPECQEGRNCIH------------GQCSKGKCICKTGYTGENCDEDVDECQDRSLCEHHCI----NTPGSYNCKCESGYVLQLDGHSCRRVDASVERPSRYCISGVNCFNGKCLNGRCTCQSGYMGESCERDINECTSEDGNRARCEQ---ICVNTEGSYECQCESGFRLQPDGYSCQKIRAPECK 1131 HSP 5 Score: 84.7297 bits (208), Expect = 1.252e-12 Identity = 76/233 (32.62%), Postives = 117/233 (50.21%), Query Frame = 1
Query: 784 DNCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKG------CQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKE----ECSKF-GTTEVVSGN--CKCKQGWKGKFCNDDVDEC--LFPVCQQI--CVNTIGSYQCSCREGFTLLSNGK 1431
+ C DC GIC+ C C G+ G RC + ++CK+R C H C + K + + +CG KE + +TCS C N CF+G+C C GF+G C+ +I+ C+ + C H C N +++C C G L D ++C++ EC++ V GN C C +G++G C+ D+DEC L P + C+N +G Y+C C G+ LL +GK
Sbjct: 1791 NQCPIDCLNGGICLNYGCECPIGYRGPRCEEM-VDICKERNP--CEHFC-YSKSEGGY--MCGCKEGYELNSDGKTCSVPIECNPLCANNAQCFRGKCICPRGFQGASCEEDIDECAMPAV-VHGCAHGCRNT-YGSYECICPQGNILMTDKRTCVEATSLVECTRPCRNGGVCHGNNICSCPRGFEGADCSKDIDECTTLSPCDPEFGSCINRVGGYECICLPGYILLLDGK 2015
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A0R3UPX3 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS9911 PE=4 SV=1) HSP 1 Score: 394.045 bits (1011), Expect = 9.757e-114 Identity = 302/807 (37.42%), Postives = 407/807 (50.43%), Query Frame = 1
Query: 787 NCVPDCGE-HGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCIC--GIKE--TQNNCLELRTCSKGCQNG-GTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN-DGKSCIKEECSK---FGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV--CQQICVNTIGSYQCSCREGFTL-LSN------GKCAINCLNNCNKNGDCLN-GICYCFSGWHGEDCSLDIDECKY-NHGCEHLCVNVPGSFN-CQCHSGFTLQINKK-KCISKSCNIECLNG-GLCDK--DKCKCPPGYIGHNCEFN-DFCHFISPC--EHNCTTINDNMVCSCLPGYDLMPDKKT--CKKLEC-PKCV--RGTC-NENKCKCPKGFAGLLCENDINECLNQTICQHVCTNT-IGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDK-----DCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHI---CEHFCMNTEGSYKCSCMPGFILSANSHSCQS-------VCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVN-SNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGNKGV 3051
C P C + G C K C C TG+ G+ C + + C + K C H C R F C+C G + T ++ E C C G G C QG+C+C +GF G+ C+ +++ C + G CE ICVN +++C C G+Q + D K C C G G C C G+ G+ C +D+DEC + C+ CVNT GSY+C C G+ + L N KC NC+ GDC G C C G+ G C + D C +H CEH+CV++PG + C+C+ G++ + +C++ C+ C G G+C ++C+C GY G CE N D C H C D+ C C PG L + T K C P C RG C + N CKC +GFAG CE N C CQ C N G + C C G A +P N TC DC +G C +C+CK G+ GK+CDEDI+EC+ I CEH C+NT GSY+C C G+ L + SCQ NG C + CKC G+ G LC+ ID C + C+ C N NG Y C+C + L+ +DG SC + ++ C PC KC++ +C C G G C D++EC P HGC+ C NTFG+YECICPPGY L D++TC ++ + C+ C NGGVC+ + C CP GF G DCG D+DEC APCD IC N YG + C C Y+L+ DG C+ + A PHL +RGRG KGV
Sbjct: 650 TCEPSCIKGQGFCHKGVCECRTGYTGKACE-RDIDECSEGKH-DCQHRCI--NRVGSFECVCNKGYRPVPTDSSRCEPLPCEPECVPGQGACRQGKCECRKGFAGEACERDVDECIESRHG---CEQICVNN-HGSYECACYEGYQQSSQDPKRCEPVRCQADCVPGQGVCWKGACHCNPGFAGESCKEDIDECKLKLDKCEHTCVNTWGSYKCECDFGYEVSLENPHKCIPSKCTSNCVPG---KGDCDEYGRCICRPGYEGPYCQHEADVCSTGHHECEHICVSLPGGRHICRCYPGYSPDPQQPHRCVAVGCDPPCKAGQGVCIPHINECRCFAGYGGDRCELNVDRSEEKQECGCSHICVGTPDSFHCECPPGMHLASNSTTSCVKDTRCNPPCWPGRGVCVDTNCCKCYEGFAGRYCEIVYNACKAFRPCQQQCVNQGDGKYECHCWPGFVPA------LPNNATTCKHACRPGVDCFNGHCVEGRCVCKQGFTGKKCDEDIDECQGEGSIHARCEHRCVNTPGSYECQCNLGYTLQPDGFSCQKNEAQNDCPSECLNNGVC--GSGCKCPDGFRGPLCEEVIDVCK-EEAPCEQLCYNKPNGGYLCACREGYELN-LDGFSC-DPSEVCDPPCSGSSKCIHGRCICPVGLQGPQCNLDVDECSMPAHVHGCLHGCWNTFGSYECICPPGYTRLPDKRTCLVTDSEDGCSRICRNGGVCKGDNECSCPRGFEGPDCGQDIDECATLAPCDPDHSICINRYGGYECVCRPGYILLLDGRHCIPEERARQAPHLIFRGRGTKGV 1434 HSP 2 Score: 340.117 bits (871), Expect = 1.259e-94 Identity = 315/951 (33.12%), Postives = 436/951 (45.85%), Query Frame = 1
Query: 289 FYLIDSFNRNDYFKSGKNQKILSDRNRFFKFDLVQF----PVDNNXXXXXXXXXXGYRNFVFTKRKIANSNFQSKNPP---PTEYVWDEIGKYWTYKLRHHQSYP-DFNFNEFPNSPCKPPFCLPRRCDQIDCGQ---SNCITNSRPCARNNQDCSMEQKRVLFGSEVVCLNKPAIDNCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLD--FSCICGIK---ETQNNCL---ELRTCSKGCQNGGTCFQ--GRCQCTEGFEGDQCQLE----INSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPV--CQQICVNTIGSYQCSCREGFTL-LSNGK------CAINCLNNCNKNGDC-LNGICYCFSGWHGEDCSLDIDECKYN-HGCEHLCVNVPGSFNCQCHSGFTL-QINKKKCISKSCNIECLNG-GLCDKDKCKCPPGYIGHNCE--FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMP-DKKTCKKLEC-PKCV--RGTCNENKCKCPKGFAGLLCENDINECLNQTI-CQHVCTNTIGSFFCRCKNGHKLAE-DKRSCIPPNKKTCLDKDCVHGQ--CFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF-ILSANSHSCQSVC--SLCKNGKCDFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNG-GKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGY-LVLDDQKTCQISTKDTMCNPHCLNG-GVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYD 2973
F L+ F RND S + I + D++ F P D T G A + PP W+E G+YW Y+ QS P + N +E C PP+C+P C G C+T Q+C + C P C C+++ CYC+ C ++ C+ L C GC F L C C I Q C +LR C C G C Q G+C C G G C + I S G CE+ CV+ E C C S L DG SC C G G C+ D+DECL + CQ CVNT GSY+C C G TL L + + C C+ + G+C L G+C C SG+ G C D+DEC GC+H C+N GSF C C GF L + K C +K CN C++G G C +CKC G+ G+ CE ++ + C+ C + + C C GY++ P D ++C +C P+C+ +G C E C+C KGF GL CE D++EC + T C+H C NT GSF C C G++ ++ D C + + DCV GQ C + C+C+ G+ G CD+D++EC++ H CEH C+N GSYKC C G+ I S++ C+ + C G+ F +K C+C+TG+TG+ C+ DIDEC +H CQH C+N GS+ C CN + D C + C C G G C KC+C+ G+ G++CE D++EC S+HGC C N G+YEC C GY D K C+ C C+ G GVC + C+C GF G C D+DEC+ DK C NT+GS+ C+C Y + +
Sbjct: 8 FQLV--FTRNDASHSEVARIINQQVDNSQSLDIINFRPQRPTDKLTTYVGVADVGGS----------AVHELEEMRPPRRLSPGLQWNEEGQYWGYQ----QSSPANPNLDE---GVCVPPYCIPAVCSDTGAGDLCPQKCVT---------QNCDI--------------------GCFPSCIAGSQCIRNICYCDAFRRATECNLISSLDCQNFFSLTCSVGC-FKPSTLTPPSGCDCAIPFHVLLQPMCATESQLR-CPNNCSGNGFCDQKTGQCICNLGSTGPSCSSKDYCVITS------GQPPCEYGCVSLNETRL-CTCPSPLVLQPDGVSCDN----------------PCPPGLTGPQCSYDIDECLTGIHGCQYYCVNTFGSYECRCPPGMTLNLQDNRTCLGQTCDPPCIPD---QGECVLGGVCECRSGFQGPSCEFDVDECITGISGCDHDCINTFGSFRCLCRPGFELDHRDNKTCFAKGCNPSCVSGQGECIDGRCKCYEGFQGNACENDLDECAYGQHNCQDRCVNTHGSFRCECRRGYEVDPRDNRSCIPRQCDPQCIPGQGICVEGHCQCIKGFRGLACEEDVDECRDGTHNCEHKCLNTHGSFECACLEGYRPSQLDSSRC----DRVKCEPDCVSGQGDCQSGICVCRPGFTGHLCDQDVDECREELHNCEHECVNLHGSYKCKCREGYRISSSDPRRCEPITCEPSCIKGQ-GFCHKGVCECRTGYTGKACERDIDECSEGKHDCQHRCINRVGSFECVCNKGYRPVPTDSSRC--EPLPCEPECVPGQGACRQGKCECRKGFAGEACERDVDECIE--SRHGCEQICVNNHGSYECACYEGYQQSSQDPKRCE----PVRCQADCVPGQGVCWKGA-CHCNPGFAGESCKEDIDECKLKL--DKCEHTCVNTWGSYKCECDFGYEVSLE 866
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: notch1b (neurogenic locus notch homolog protein 1-like [Source:NCBI gene;Acc:103025197]) HSP 1 Score: 229.18 bits (583), Expect = 7.386e-61 Identity = 245/793 (30.90%), Postives = 342/793 (43.13%), Query Frame = 1
Query: 802 CGEHGICVKSR----CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT----LLSNGKCAINCLNNCNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFN-DFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCV------RGTC----NENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C G C+ ++ C C GW GE C + C G + R F C C T C C S CQ G C + C C G+ G C +++ CS +G CEH C+N + +FQCKCQ G+ + + D C+ C T ++ +C C G++GKFC + DEC C C++ I +YQC C GF+ N +CA C C++G C C G+ G+ C DIDEC N LC + F C C +G+T ++ N +C+S C NGG C + C CP G G NCE N D C +PC+ C + C+C PGY K C + +C GTC N C+C G+ C++ +NECL+ C + + + C C +G + C+ N TC KD G C C++G+ G C +INEC + + C++ YKC+C+ L +C+++ C C N CK C GW G+ C++DI+EC+ N + C NS GSY CSC S GR+C D C +PC NGG C + C C PG+ G CEEDINEC K+G C + +Y C CPPG+ ++ C+ +T D C NGG C D C C GF G C D++EC PC G C ++YG++ C C Y
Sbjct: 305 CQNGGTCLNTQGGYNCVCVNGWTGEDCSKNIDDCADAA----CNVGATCHDRVASFFCECPPGRTGLLCHLNDACISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECS---LGANPCEHAGKCLNT-KGSFQCKCQQGYVGPRCELDVNECLSNPCQNDATCLDQIGGFHCICMAGYEGKFCEINTDECASMPCLNNGKCIDKINNYQCECPTGFSGNQCQFDNDECAST---PCKNGAKCIDGPNMYTCQCTEGYTGQHCETDIDECLSNPCHYGLCKDSLAGFTCHCRAGYTGRLCEANINECLSHPCQ----NGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQS-NPCDFGKCIDKINGYECACEPGYT----GKLCS-INIDECAINPCHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNECLSNPCIHGHCEDRVNGYNCICDSGWSGNNCDINNNECESNPCM--NGGTC--KDMTSGYV----CSCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL----LPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNPCRNGATCQNSIGSYRCSCK-----SGYTGRNCETDIDDCKPNPCSNGGFCKDGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNG--ANCTDCVNSYTCTCPPGFSGIN----CENNTPDCT-ESSCFNGGTCVDGINTFSCLCLAGFTGSYCQHDINECDS-KPCMN-GGTCQDSYGTYKCTCPHGY 1050 HSP 2 Score: 192.586 bits (488), Expect = 2.650e-49 Identity = 245/834 (29.38%), Postives = 360/834 (43.17%), Query Frame = 1
Query: 802 CGEHGICVKS-----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG---CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL---------SNGKCAINCL-----------------------------NNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSK-----CICKSGYRGKRCDEDINECKKYSHICEHF-CMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPH-CLNGGVCRDMS-----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
CG G C + +C C GW G+ C +P C C +G + C C + C ++ C+ C NGG C RC C + G C+ CS C H CV +GE +++C C GF N + C C GT V + NC+CK W G+FC +DV+EC L P CQ C+NT G Y C C G+T ++ C + N C K +C +NG IC C G+ G C D+DEC + CEH C+N GSF C+C G+ +++ +C+S C + CL+ GG C C GY G CE N D C + PC +N I+ +N C C G+ D C C KC+ G N C+C +G+ G CE DI+ECL+ +C +++ F C C+ G+ R C N CL C +G + C+C G G C+ ++++C+ S+ C+ C++ Y+C+C PG+ + S N C + C NG + C+C+ G+ C ++ECL N C H +C + Y+C C+ S G +C N+ C S+PC NGG C + C C+ G++G +C+ +INEC + + C+ G C + Y+C C L+ + C+ T CNP C N GVC++ C CP G+ G C +D++EC + PC + C N+ GS+ C C S Y
Sbjct: 110 CGNGGTCELTSVRTYKCKCPPGWTGKNCQQADP--CASNP---CANGGQCSPFDSHYICTCTPFFSGETCKQDVNECALSPFPCNNGGVCVNEVGSYRCNCPTEYTGKHCETLYQPCSP-----SPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNTYNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVNGWTGEDCSKNIDDCADAACNVGATCHDRVASFFCECPPGRTGLLCHLNDACISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECSLGANPCEHAGKCLNTKGSFQCKCQQGYVGPRCELDVNECLSNPCQNDATCLDQIGGF----HCICMAGYEGKFCEINTDECASM-PCLNNGKCIDKINNYQCECPTGFSGNQCQFDNDECASTPCKNGAKCIDGP-NMYTCQCTEGYTGQHCETDIDECLSNPCHYGLCKDSLAGFTCHCRAGYT----GRLC-EANINECLSHPCQNGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQ--SNPCDFGKCIDKINGYECACEPGYTGKLCSINIDEC--AINPCHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNECLSN--PCIHGHCEDRVNGYNCICD-----SGWSGNNCDINNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINEC----ASNPCLNQGTCIDDVAGYKCNC----LLPYTGENCE--TLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVK-NPC-RNGATCQNSIGSYRCSCKSGYT 899 HSP 3 Score: 187.193 bits (474), Expect = 1.316e-47 Identity = 235/837 (28.08%), Postives = 337/837 (40.26%), Query Frame = 1
Query: 1012 CSKGCQNGGTCFQ------GRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ----LDNDGKSCIKEECSKFGT---TEVVSGNCKCKQGWKGK-------------------------------------FCNDDVDECL---FPVCQQ-ICVNTIGSYQCSCR---------------------EGFTLLSNGKCAINCL-------NNCNKN------------GDCLNGI----CYCFSGWHGEDCSLDIDECKY-NHGCEH--LCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCE--HNCTT--INDNMVCSCLPGYDLMP---DKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGH-----KLAEDKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF--------ILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECL-------------------------------LNQHKCQHN------CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTM 2994
CS+ CQNGGTC G C+C E F G CQ N C N + + + +F C+C G+ L C C GT T V + CKC GW GK C DV+EC FP +CVN +GSY+C+C G T + G+ + C NC +N G C++G+ C C W G+ C+ D++EC + C++ C+N G +NC C +G+T + N C +CN+ C+CPPG G C ND C +PC+ NC T +N +C+C GY D C P G C K CKC +G+ G CE D+NECL+ CQ+ C + IG F C C G+ ++ D+ + +P N C+DK N +C C +G+ G +C D +EC C++ Y C C G+ I S+ C LCK+ F C C+ G+TG LC+ +I+ECL +N CQ N C++ Y C+C P Y G+ C D C+ +PC NGG C++ C+C+ GY+ +C+ +NEC +S G C + Y CIC G+ C I+ + NP C+NGG C+DM+ C C GF G +C +++EC PC +G C + + C C +L Y G +C T+
Sbjct: 24 CSEKCQNGGTCVPTPDGRGGECKCPEKFWGSACQFS-NPCLPNPCWNGGVCQPVIRDNKVDFVCQCHLGYMDPRCLTPTDNPCRSSPCGNGGTCELTSVRTYKCKCPPGWTGKNCQQADPCASNPCANGGQCSPFDSHYICTCTPFFSGETCKQDVNECALSPFPCNNGGVCVNEVGSYRCNCPTEYTGKHCETLYQPCSPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNTYNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVNGWTGEDCSKNIDDCADAACNVGATCHDRVASFFCECPPGRTGLLCHLNDAC-ISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECSLGANPCEHAGKCLNTKGSFQCKCQQGYVGPRCELDVNECLSNP-CQNDATCLDQIGGFHCICMAGYEGKFCEINTDECASMPCLNNGKCIDK------INNYQCECPTGFSGNQCQFDNDECASTPCKNGAKCIDGPNMYTCQCTEGYTGQHCETDIDECLSNPCHY--GLCKDSLAGFT--CHCRAGYTGRLCEANINECLSHPCQNGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQSNPCDFGKCIDKINGYECACE-PGYT----GKLCSINIDECAINPCHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNEC---LSNPCIHGHCEDRVNGYNCICDSGW----SGNNCDINNNECESNP-CMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECAS-NPCLN-QGTCIDDVAGYKCNC----LLPYTGENCETL 828 HSP 4 Score: 181.8 bits (460), Expect = 6.144e-46 Identity = 219/726 (30.17%), Postives = 313/726 (43.11%), Query Frame = 1
Query: 1024 CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT-TEVVSGN-CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT-----LLSNGKCAINCLNN--CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQ--------SVCSLCKN-GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQW---PISKHG-CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGV--CRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLR--GICYNTYGSFYCQCSSNYVLM---YDGTSCMTMK 2997
C NGGTC G CQC +G+ CQ ++N C + C H + N + C C SG+ +N + C C GT ++ SG C C+ G+ G C +++EC C Q C++ + Y+C+C +T L + C NN C ++ D + C C GW G+ C +DI+EC N C + C N GS+ C C SG+T + N + I C NGG C D C C PG+ G CE + +PC++ NCT ++ C+C PG+ + PD CV G N C C GF G C++DINEC D + C+ N TC D + KC C GYRG C E +N CK C + +Y C C G+ S SC+ V LC+N G C D N C+C+ G+TG C+ +DEC+ N + C + G YSC C +P Y G +C E N+ S PC+NGG C++ KC C G G CE ++++C P++K C G C + G Y C+CPPGY+ + C+ + + NP C G C ++ RC C G+ G C D C + PC + NT F C+C + YD +C +++
Sbjct: 686 CHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNECL-----SNPCIHGHCEDRVNGYNCICDSGWSGNNCDINNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNP-CRNGATCQNSIGSYRCSCKSGYTGR-NCETDIDDCKPNPCSNGGFCKDGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNGANCTDCVNSYTCTCPPGFSGINCENNTPDCTESSCFNGGTCVDGI-NTFSCLCLAGFTGSYCQHDINEC-----------------------------DSKPCM--NGGTCQDSYGTY------KCTCPHGYRGFNCQELVNWCKPSPCKNGGTCRQSGTTYTCQCQTGWTGLYCDVPSVSCEVAAKQQGVEVARLCRNSGLCLDAGNTHYCQCQAGYTGSYCEEQVDECIPNPCQNGATCTDYLGGYSCEC-VPGY----HGVNCSSEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRCVDRVGGYHCVCPPGYV----GERCEGDVNECLSNP-CDPRGTHSCIQLTNNYRCECRTGYTGQRCDTVFDGC-KGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAQACGSLQ 1355 HSP 5 Score: 134.806 bits (338), Expect = 1.923e-31 Identity = 201/727 (27.65%), Postives = 289/727 (39.75%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQSGFQLDN---DGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINC-LNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNH-------------------------GCEH--------------LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNC-EFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM----PDK--KTCKKLECPKCVR-----GTC----NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKL---AEDKRSCIPP---NKKTCLD----------------------KDCV--------HGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICE----HFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKC------------KCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDS--CSSPCKNGGKCVNSK------CKCKPGYNGDSC 2613
C+HG D R ++CIC + NNC + C S C NGGTC C C GF G CQ IN C+ + C+N+G ++C C + +N C + C G + + S +C C +GW+G+ C D++EC+ C+ C N+IGSY+CSC+ G+T + +C N C+ G C +G+ C C G+ G C DI+EC N CE+ CV+ +F+C C +GFT Q + +C SK C +NGG C KC CP GY G NC E ++C SPC++ C C C G+ + P + K + + R G C N + C+C G+ G CE ++EC+ CQ+ CT+ +G + C C G+ + + C+ N TC+D DC +CFN C+C GY G+RC+ D+NEC S+ C+ H C+ +Y+C C G+ C +V CK C C KC G+TG C+ D C Q K CV+ + + C C+ F G C +D S+PC NGG C S C C +NG C
Sbjct: 724 CIHGHCED-RVNGYNCICDSGWSGNNCDINNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCLLPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNPCRNGATCQNSIGSYRCSCKSGYTGRNCETDIDDCKPNPCSNGGFCKDGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNGANCTDCVNSYTCTCPPGFSGINCENNTPDCTESSCFNGGTCVDGINTFSCLCLAGFTGSYCQHDINECDSKPC----MNGGTCQDSYGTYKCTCPHGYRGFNCQELVNWCK-PSPCKNGGTCRQSGTTYTCQCQTGWTGLYCDVPSVSCEVAAKQQGVEVARLCRNSGLCLDAGNTHYCQCQAGYTGSYCEEQVDECI-PNPCQNGATCTDYLGGYSCECVPGYHGVNCSSEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRCVDRVGGYHCVCPPGYVGERCEGDVNEC--LSNPCDPRGTHSCIQLTNNYRCECRTGYT----GQRCDTVFDGCKGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAQACGSLQCKNGGTCVSGHKNPRCLCSPSFT-----GPECQYPSDGPCLSNPCYNGGTCEPSTESPYFHCVCPADFNGLLC 1423
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: notch1b (neurogenic locus notch homolog protein 1-like [Source:NCBI gene;Acc:103025197]) HSP 1 Score: 229.18 bits (583), Expect = 7.386e-61 Identity = 245/793 (30.90%), Postives = 342/793 (43.13%), Query Frame = 1
Query: 802 CGEHGICVKSR----CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT----LLSNGKCAINCLNNCNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFN-DFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCV------RGTC----NENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C G C+ ++ C C GW GE C + C G + R F C C T C C S CQ G C + C C G+ G C +++ CS +G CEH C+N + +FQCKCQ G+ + + D C+ C T ++ +C C G++GKFC + DEC C C++ I +YQC C GF+ N +CA C C++G C C G+ G+ C DIDEC N LC + F C C +G+T ++ N +C+S C NGG C + C CP G G NCE N D C +PC+ C + C+C PGY K C + +C GTC N C+C G+ C++ +NECL+ C + + + C C +G + C+ N TC KD G C C++G+ G C +INEC + + C++ YKC+C+ L +C+++ C C N CK C GW G+ C++DI+EC+ N + C NS GSY CSC S GR+C D C +PC NGG C + C C PG+ G CEEDINEC K+G C + +Y C CPPG+ ++ C+ +T D C NGG C D C C GF G C D++EC PC G C ++YG++ C C Y
Sbjct: 305 CQNGGTCLNTQGGYNCVCVNGWTGEDCSKNIDDCADAA----CNVGATCHDRVASFFCECPPGRTGLLCHLNDACISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECS---LGANPCEHAGKCLNT-KGSFQCKCQQGYVGPRCELDVNECLSNPCQNDATCLDQIGGFHCICMAGYEGKFCEINTDECASMPCLNNGKCIDKINNYQCECPTGFSGNQCQFDNDECAST---PCKNGAKCIDGPNMYTCQCTEGYTGQHCETDIDECLSNPCHYGLCKDSLAGFTCHCRAGYTGRLCEANINECLSHPCQ----NGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQS-NPCDFGKCIDKINGYECACEPGYT----GKLCS-INIDECAINPCHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNECLSNPCIHGHCEDRVNGYNCICDSGWSGNNCDINNNECESNPCM--NGGTC--KDMTSGYV----CSCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL----LPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNPCRNGATCQNSIGSYRCSCK-----SGYTGRNCETDIDDCKPNPCSNGGFCKDGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNG--ANCTDCVNSYTCTCPPGFSGIN----CENNTPDCT-ESSCFNGGTCVDGINTFSCLCLAGFTGSYCQHDINECDS-KPCMN-GGTCQDSYGTYKCTCPHGY 1050 HSP 2 Score: 192.586 bits (488), Expect = 2.650e-49 Identity = 245/834 (29.38%), Postives = 360/834 (43.17%), Query Frame = 1
Query: 802 CGEHGICVKS-----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG---CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL---------SNGKCAINCL-----------------------------NNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSK-----CICKSGYRGKRCDEDINECKKYSHICEHF-CMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPH-CLNGGVCRDMS-----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
CG G C + +C C GW G+ C +P C C +G + C C + C ++ C+ C NGG C RC C + G C+ CS C H CV +GE +++C C GF N + C C GT V + NC+CK W G+FC +DV+EC L P CQ C+NT G Y C C G+T ++ C + N C K +C +NG IC C G+ G C D+DEC + CEH C+N GSF C+C G+ +++ +C+S C + CL+ GG C C GY G CE N D C + PC +N I+ +N C C G+ D C C KC+ G N C+C +G+ G CE DI+ECL+ +C +++ F C C+ G+ R C N CL C +G + C+C G G C+ ++++C+ S+ C+ C++ Y+C+C PG+ + S N C + C NG + C+C+ G+ C ++ECL N C H +C + Y+C C+ S G +C N+ C S+PC NGG C + C C+ G++G +C+ +INEC + + C+ G C + Y+C C L+ + C+ T CNP C N GVC++ C CP G+ G C +D++EC + PC + C N+ GS+ C C S Y
Sbjct: 110 CGNGGTCELTSVRTYKCKCPPGWTGKNCQQADP--CASNP---CANGGQCSPFDSHYICTCTPFFSGETCKQDVNECALSPFPCNNGGVCVNEVGSYRCNCPTEYTGKHCETLYQPCSP-----SPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNTYNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVNGWTGEDCSKNIDDCADAACNVGATCHDRVASFFCECPPGRTGLLCHLNDACISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECSLGANPCEHAGKCLNTKGSFQCKCQQGYVGPRCELDVNECLSNPCQNDATCLDQIGGF----HCICMAGYEGKFCEINTDECASM-PCLNNGKCIDKINNYQCECPTGFSGNQCQFDNDECASTPCKNGAKCIDGP-NMYTCQCTEGYTGQHCETDIDECLSNPCHYGLCKDSLAGFTCHCRAGYT----GRLC-EANINECLSHPCQNGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQ--SNPCDFGKCIDKINGYECACEPGYTGKLCSINIDEC--AINPCHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNECLSN--PCIHGHCEDRVNGYNCICD-----SGWSGNNCDINNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINEC----ASNPCLNQGTCIDDVAGYKCNC----LLPYTGENCE--TLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVK-NPC-RNGATCQNSIGSYRCSCKSGYT 899 HSP 3 Score: 187.193 bits (474), Expect = 1.316e-47 Identity = 235/837 (28.08%), Postives = 337/837 (40.26%), Query Frame = 1
Query: 1012 CSKGCQNGGTCFQ------GRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ----LDNDGKSCIKEECSKFGT---TEVVSGNCKCKQGWKGK-------------------------------------FCNDDVDECL---FPVCQQ-ICVNTIGSYQCSCR---------------------EGFTLLSNGKCAINCL-------NNCNKN------------GDCLNGI----CYCFSGWHGEDCSLDIDECKY-NHGCEH--LCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCE--HNCTT--INDNMVCSCLPGYDLMP---DKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGH-----KLAEDKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF--------ILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECL-------------------------------LNQHKCQHN------CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTM 2994
CS+ CQNGGTC G C+C E F G CQ N C N + + + +F C+C G+ L C C GT T V + CKC GW GK C DV+EC FP +CVN +GSY+C+C G T + G+ + C NC +N G C++G+ C C W G+ C+ D++EC + C++ C+N G +NC C +G+T + N C +CN+ C+CPPG G C ND C +PC+ NC T +N +C+C GY D C P G C K CKC +G+ G CE D+NECL+ CQ+ C + IG F C C G+ ++ D+ + +P N C+DK N +C C +G+ G +C D +EC C++ Y C C G+ I S+ C LCK+ F C C+ G+TG LC+ +I+ECL +N CQ N C++ Y C+C P Y G+ C D C+ +PC NGG C++ C+C+ GY+ +C+ +NEC +S G C + Y CIC G+ C I+ + NP C+NGG C+DM+ C C GF G +C +++EC PC +G C + + C C +L Y G +C T+
Sbjct: 24 CSEKCQNGGTCVPTPDGRGGECKCPEKFWGSACQFS-NPCLPNPCWNGGVCQPVIRDNKVDFVCQCHLGYMDPRCLTPTDNPCRSSPCGNGGTCELTSVRTYKCKCPPGWTGKNCQQADPCASNPCANGGQCSPFDSHYICTCTPFFSGETCKQDVNECALSPFPCNNGGVCVNEVGSYRCNCPTEYTGKHCETLYQPCSPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNTYNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVNGWTGEDCSKNIDDCADAACNVGATCHDRVASFFCECPPGRTGLLCHLNDAC-ISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECSLGANPCEHAGKCLNTKGSFQCKCQQGYVGPRCELDVNECLSNP-CQNDATCLDQIGGFHCICMAGYEGKFCEINTDECASMPCLNNGKCIDK------INNYQCECPTGFSGNQCQFDNDECASTPCKNGAKCIDGPNMYTCQCTEGYTGQHCETDIDECLSNPCHY--GLCKDSLAGFT--CHCRAGYTGRLCEANINECLSHPCQNGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQSNPCDFGKCIDKINGYECACE-PGYT----GKLCSINIDECAINPCHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNEC---LSNPCIHGHCEDRVNGYNCICDSGW----SGNNCDINNNECESNP-CMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECAS-NPCLN-QGTCIDDVAGYKCNC----LLPYTGENCETL 828 HSP 4 Score: 181.8 bits (460), Expect = 6.144e-46 Identity = 219/726 (30.17%), Postives = 313/726 (43.11%), Query Frame = 1
Query: 1024 CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT-TEVVSGN-CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT-----LLSNGKCAINCLNN--CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQ--------SVCSLCKN-GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQW---PISKHG-CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGV--CRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLR--GICYNTYGSFYCQCSSNYVLM---YDGTSCMTMK 2997
C NGGTC G CQC +G+ CQ ++N C + C H + N + C C SG+ +N + C C GT ++ SG C C+ G+ G C +++EC C Q C++ + Y+C+C +T L + C NN C ++ D + C C GW G+ C +DI+EC N C + C N GS+ C C SG+T + N + I C NGG C D C C PG+ G CE + +PC++ NCT ++ C+C PG+ + PD CV G N C C GF G C++DINEC D + C+ N TC D + KC C GYRG C E +N CK C + +Y C C G+ S SC+ V LC+N G C D N C+C+ G+TG C+ +DEC+ N + C + G YSC C +P Y G +C E N+ S PC+NGG C++ KC C G G CE ++++C P++K C G C + G Y C+CPPGY+ + C+ + + NP C G C ++ RC C G+ G C D C + PC + NT F C+C + YD +C +++
Sbjct: 686 CHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNECL-----SNPCIHGHCEDRVNGYNCICDSGWSGNNCDINNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNP-CRNGATCQNSIGSYRCSCKSGYTGR-NCETDIDDCKPNPCSNGGFCKDGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNGANCTDCVNSYTCTCPPGFSGINCENNTPDCTESSCFNGGTCVDGI-NTFSCLCLAGFTGSYCQHDINEC-----------------------------DSKPCM--NGGTCQDSYGTY------KCTCPHGYRGFNCQELVNWCKPSPCKNGGTCRQSGTTYTCQCQTGWTGLYCDVPSVSCEVAAKQQGVEVARLCRNSGLCLDAGNTHYCQCQAGYTGSYCEEQVDECIPNPCQNGATCTDYLGGYSCEC-VPGY----HGVNCSSEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRCVDRVGGYHCVCPPGYV----GERCEGDVNECLSNP-CDPRGTHSCIQLTNNYRCECRTGYTGQRCDTVFDGC-KGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAQACGSLQ 1355 HSP 5 Score: 134.806 bits (338), Expect = 1.923e-31 Identity = 201/727 (27.65%), Postives = 289/727 (39.75%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQSGFQLDN---DGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINC-LNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNH-------------------------GCEH--------------LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNC-EFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM----PDK--KTCKKLECPKCVR-----GTC----NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKL---AEDKRSCIPP---NKKTCLD----------------------KDCV--------HGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICE----HFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKC------------KCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDS--CSSPCKNGGKCVNSK------CKCKPGYNGDSC 2613
C+HG D R ++CIC + NNC + C S C NGGTC C C GF G CQ IN C+ + C+N+G ++C C + +N C + C G + + S +C C +GW+G+ C D++EC+ C+ C N+IGSY+CSC+ G+T + +C N C+ G C +G+ C C G+ G C DI+EC N CE+ CV+ +F+C C +GFT Q + +C SK C +NGG C KC CP GY G NC E ++C SPC++ C C C G+ + P + K + + R G C N + C+C G+ G CE ++EC+ CQ+ CT+ +G + C C G+ + + C+ N TC+D DC +CFN C+C GY G+RC+ D+NEC S+ C+ H C+ +Y+C C G+ C +V CK C C KC G+TG C+ D C Q K CV+ + + C C+ F G C +D S+PC NGG C S C C +NG C
Sbjct: 724 CIHGHCED-RVNGYNCICDSGWSGNNCDINNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCLLPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNPCRNGATCQNSIGSYRCSCKSGYTGRNCETDIDDCKPNPCSNGGFCKDGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNGANCTDCVNSYTCTCPPGFSGINCENNTPDCTESSCFNGGTCVDGINTFSCLCLAGFTGSYCQHDINECDSKPC----MNGGTCQDSYGTYKCTCPHGYRGFNCQELVNWCK-PSPCKNGGTCRQSGTTYTCQCQTGWTGLYCDVPSVSCEVAAKQQGVEVARLCRNSGLCLDAGNTHYCQCQAGYTGSYCEEQVDECI-PNPCQNGATCTDYLGGYSCECVPGYHGVNCSSEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRCVDRVGGYHCVCPPGYVGERCEGDVNEC--LSNPCDPRGTHSCIQLTNNYRCECRTGYT----GQRCDTVFDGCKGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAQACGSLQCKNGGTCVSGHKNPRCLCSPSFT-----GPECQYPSDGPCLSNPCYNGGTCEPSTESPYFHCVCPADFNGLLC 1423
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: notch1b (neurogenic locus notch homolog protein 1-like [Source:NCBI gene;Acc:103025197]) HSP 1 Score: 228.409 bits (581), Expect = 1.282e-60 Identity = 245/793 (30.90%), Postives = 342/793 (43.13%), Query Frame = 1
Query: 802 CGEHGICVKSR----CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC-SKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT----LLSNGKCAINCLNNCNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFN-DFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCV------RGTC----NENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE--------DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
C G C+ ++ C C GW GE C + C G + R F C C T C C S CQ G C + C C G+ G C +++ CS +G CEH C+N + +FQCKCQ G+ + + D C+ C T ++ +C C G++GKFC + DEC C C++ I +YQC C GF+ N +CA C C++G C C G+ G+ C DIDEC N LC + F C C +G+T ++ N +C+S C NGG C + C CP G G NCE N D C +PC+ C + C+C PGY K C + +C GTC N C+C G+ C++ +NECL+ C + + + C C +G + C+ N TC KD G C C++G+ G C +INEC + + C++ YKC+C+ L +C+++ C C N CK C GW G+ C++DI+EC+ N + C NS GSY CSC S GR+C D C +PC NGG C + C C PG+ G CEEDINEC K+G C + +Y C CPPG+ ++ C+ +T D C NGG C D C C GF G C D++EC PC G C ++YG++ C C Y
Sbjct: 279 CQNGGTCLNTQGGYNCVCVNGWTGEDCSKNIDDCADAA----CNVGATCHDRVASFFCECPPGRTGLLCHLNDACISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECS---LGANPCEHAGKCLNT-KGSFQCKCQQGYVGPRCELDVNECLSNPCQNDATCLDQIGGFHCICMAGYEGKFCEINTDECASMPCLNNGKCIDKINNYQCECPTGFSGNQCQFDNDECAST---PCKNGAKCIDGPNMYTCQCTEGYTGQHCETDIDECLSNPCHYGLCKDSLAGFTCHCRAGYTGRLCEANINECLSHPCQ----NGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQS-NPCDFGKCIDKINGYECACEPGYT----GKLCS-INIDECAINPCHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNECLSNPCIHGHCEDRVNGYNCICDSGWSGNNCDINNNECESNPCM--NGGTC--KDMTSGYV----CSCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL----LPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNPCRNGATCQNSIGSYRCSCK-----SGYTGRNCETDIDDCKPNPCSNGGFCKDGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNG--ANCTDCVNSYTCTCPPGFSGIN----CENNTPDCT-ESSCFNGGTCVDGINTFSCLCLAGFTGSYCQHDINECDS-KPCMN-GGTCQDSYGTYKCTCPHGY 1024 HSP 2 Score: 191.815 bits (486), Expect = 4.558e-49 Identity = 245/834 (29.38%), Postives = 360/834 (43.17%), Query Frame = 1
Query: 802 CGEHGICVKS-----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG---CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFTLL---------SNGKCAINCL-----------------------------NNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSK-----CICKSGYRGKRCDEDINECKKYSHICEHF-CMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPH-CLNGGVCRDMS-----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
CG G C + +C C GW G+ C +P C C +G + C C + C ++ C+ C NGG C RC C + G C+ CS C H CV +GE +++C C GF N + C C GT V + NC+CK W G+FC +DV+EC L P CQ C+NT G Y C C G+T ++ C + N C K +C +NG IC C G+ G C D+DEC + CEH C+N GSF C+C G+ +++ +C+S C + CL+ GG C C GY G CE N D C + PC +N I+ +N C C G+ D C C KC+ G N C+C +G+ G CE DI+ECL+ +C +++ F C C+ G+ R C N CL C +G + C+C G G C+ ++++C+ S+ C+ C++ Y+C+C PG+ + S N C + C NG + C+C+ G+ C ++ECL N C H +C + Y+C C+ S G +C N+ C S+PC NGG C + C C+ G++G +C+ +INEC + + C+ G C + Y+C C L+ + C+ T CNP C N GVC++ C CP G+ G C +D++EC + PC + C N+ GS+ C C S Y
Sbjct: 84 CGNGGTCELTSVRTYKCKCPPGWTGKNCQQADP--CASNP---CANGGQCSPFDSHYICTCTPFFSGETCKQDVNECALSPFPCNNGGVCVNEVGSYRCNCPTEYTGKHCETLYQPCSP-----SPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNTYNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVNGWTGEDCSKNIDDCADAACNVGATCHDRVASFFCECPPGRTGLLCHLNDACISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECSLGANPCEHAGKCLNTKGSFQCKCQQGYVGPRCELDVNECLSNPCQNDATCLDQIGGF----HCICMAGYEGKFCEINTDECASM-PCLNNGKCIDKINNYQCECPTGFSGNQCQFDNDECASTPCKNGAKCIDGP-NMYTCQCTEGYTGQHCETDIDECLSNPCHYGLCKDSLAGFTCHCRAGYT----GRLC-EANINECLSHPCQNGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQ--SNPCDFGKCIDKINGYECACEPGYTGKLCSINIDEC--AINPCHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNECLSN--PCIHGHCEDRVNGYNCICD-----SGWSGNNCDINNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINEC----ASNPCLNQGTCIDDVAGYKCNC----LLPYTGENCE--TLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVK-NPC-RNGATCQNSIGSYRCSCKSGYT 873 HSP 3 Score: 181.03 bits (458), Expect = 1.019e-45 Identity = 219/726 (30.17%), Postives = 313/726 (43.11%), Query Frame = 1
Query: 1024 CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT-TEVVSGN-CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT-----LLSNGKCAINCLNN--CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM------PDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQ--------SVCSLCKN-GKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQW---PISKHG-CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGV--CRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLR--GICYNTYGSFYCQCSSNYVLM---YDGTSCMTMK 2997
C NGGTC G CQC +G+ CQ ++N C + C H + N + C C SG+ +N + C C GT ++ SG C C+ G+ G C +++EC C Q C++ + Y+C+C +T L + C NN C ++ D + C C GW G+ C +DI+EC N C + C N GS+ C C SG+T + N + I C NGG C D C C PG+ G CE + +PC++ NCT ++ C+C PG+ + PD CV G N C C GF G C++DINEC D + C+ N TC D + KC C GYRG C E +N CK C + +Y C C G+ S SC+ V LC+N G C D N C+C+ G+TG C+ +DEC+ N + C + G YSC C +P Y G +C E N+ S PC+NGG C++ KC C G G CE ++++C P++K C G C + G Y C+CPPGY+ + C+ + + NP C G C ++ RC C G+ G C D C + PC + NT F C+C + YD +C +++
Sbjct: 660 CHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNECL-----SNPCIHGHCEDRVNGYNCICDSGWSGNNCDINNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNP-CRNGATCQNSIGSYRCSCKSGYTGR-NCETDIDDCKPNPCSNGGFCKDGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNGANCTDCVNSYTCTCPPGFSGINCENNTPDCTESSCFNGGTCVDGI-NTFSCLCLAGFTGSYCQHDINEC-----------------------------DSKPCM--NGGTCQDSYGTY------KCTCPHGYRGFNCQELVNWCKPSPCKNGGTCRQSGTTYTCQCQTGWTGLYCDVPSVSCEVAAKQQGVEVARLCRNSGLCLDAGNTHYCQCQAGYTGSYCEEQVDECIPNPCQNGATCTDYLGGYSCEC-VPGY----HGVNCSSEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRCVDRVGGYHCVCPPGYV----GERCEGDVNECLSNP-CDPRGTHSCIQLTNNYRCECRTGYTGQRCDTVFDGC-KGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAQACGSLQ 1329 HSP 4 Score: 177.563 bits (449), Expect = 1.279e-44 Identity = 226/797 (28.36%), Postives = 328/797 (41.15%), Query Frame = 1
Query: 1024 CQNGGTC--------FQGRCQCTEGFEGDQCQLEI-NSCSRGQMGNR-TCEHICVNEGENNFQCKCQSGFQLDN--DGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECL---FPVCQQ-ICVNTIGSYQCSCR---------------------EGFTLLSNGKCAINCL-------NNCNKN------------GDCLNGI----CYCFSGWHGEDCSLDIDECKY-NHGCEH--LCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCE--HNCTT--INDNMVCSCLPGYDLMP---DKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGH-----KLAEDKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF--------ILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECL-------------------------------LNQHKCQHN------CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTM 2994
C NGG C CQC G+ +C N C GN TCE V ++CKC G+ N C C+ G + C C + G+ C DV+EC FP +CVN +GSY+C+C G T + G+ + C NC +N G C++G+ C C W G+ C+ D++EC + C++ C+N G +NC C +G+T + N C +CN+ C+CPPG G C ND C +PC+ NC T +N +C+C GY D C P G C K CKC +G+ G CE D+NECL+ CQ+ C + IG F C C G+ ++ D+ + +P N C+DK N +C C +G+ G +C D +EC C++ Y C C G+ I S+ C LCK+ F C C+ G+TG LC+ +I+ECL +N CQ N C++ Y C+C P Y G+ C D C+ +PC NGG C++ C+C+ GY+ +C+ +NEC +S G C + Y CIC G+ C I+ + NP C+NGG C+DM+ C C GF G +C +++EC PC +G C + + C C +L Y G +C T+
Sbjct: 41 CWNGGVCQPVIRDNKVDFVCQCHLGYMDPRCLTPTDNPCRSSPCGNGGTCELTSVR----TYKCKCPPGWTGKNCQQADPCASNPCANGGQCSPFDSHYICTCTPFFSGETCKQDVNECALSPFPCNNGGVCVNEVGSYRCNCPTEYTGKHCETLYQPCSPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNTYNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVNGWTGEDCSKNIDDCADAACNVGATCHDRVASFFCECPPGRTGLLCHLNDAC-ISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECSLGANPCEHAGKCLNTKGSFQCKCQQGYVGPRCELDVNECLSNP-CQNDATCLDQIGGFHCICMAGYEGKFCEINTDECASMPCLNNGKCIDK------INNYQCECPTGFSGNQCQFDNDECASTPCKNGAKCIDGPNMYTCQCTEGYTGQHCETDIDECLSNPCHY--GLCKDSLAGFT--CHCRAGYTGRLCEANINECLSHPCQNGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQSNPCDFGKCIDKINGYECACE-PGYT----GKLCSINIDECAINPCHNGGTCIDGVNGFMCQCRDGYHDPTCQSQLNEC---LSNPCIHGHCEDRVNGYNCICDSGW----SGNNCDINNNECESNP-CMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECAS-NPCLN-QGTCIDDVAGYKCNC----LLPYTGENCETL 802 HSP 5 Score: 134.42 bits (337), Expect = 3.122e-31 Identity = 201/727 (27.65%), Postives = 289/727 (39.75%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQSGFQLDN---DGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINC-LNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNH-------------------------GCEH--------------LCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNC-EFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLM----PDK--KTCKKLECPKCVR-----GTC----NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKL---AEDKRSCIPP---NKKTCLD----------------------KDCV--------HGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICE----HFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKC------------KCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDS--CSSPCKNGGKCVNSK------CKCKPGYNGDSC 2613
C+HG D R ++CIC + NNC + C S C NGGTC C C GF G CQ IN C+ + C+N+G ++C C + +N C + C G + + S +C C +GW+G+ C D++EC+ C+ C N+IGSY+CSC+ G+T + +C N C+ G C +G+ C C G+ G C DI+EC N CE+ CV+ +F+C C +GFT Q + +C SK C +NGG C KC CP GY G NC E ++C SPC++ C C C G+ + P + K + + R G C N + C+C G+ G CE ++EC+ CQ+ CT+ +G + C C G+ + + C+ N TC+D DC +CFN C+C GY G+RC+ D+NEC S+ C+ H C+ +Y+C C G+ C +V CK C C KC G+TG C+ D C Q K CV+ + + C C+ F G C +D S+PC NGG C S C C +NG C
Sbjct: 698 CIHGHCED-RVNGYNCICDSGWSGNNCDINNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCLLPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNPCRNGATCQNSIGSYRCSCKSGYTGRNCETDIDDCKPNPCSNGGFCKDGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNGANCTDCVNSYTCTCPPGFSGINCENNTPDCTESSCFNGGTCVDGINTFSCLCLAGFTGSYCQHDINECDSKPC----MNGGTCQDSYGTYKCTCPHGYRGFNCQELVNWCK-PSPCKNGGTCRQSGTTYTCQCQTGWTGLYCDVPSVSCEVAAKQQGVEVARLCRNSGLCLDAGNTHYCQCQAGYTGSYCEEQVDECI-PNPCQNGATCTDYLGGYSCECVPGYHGVNCSSEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRCVDRVGGYHCVCPPGYVGERCEGDVNEC--LSNPCDPRGTHSCIQLTNNYRCECRTGYT----GQRCDTVFDGCKGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAQACGSLQCKNGGTCVSGHKNPRCLCSPSFT-----GPECQYPSDGPCLSNPCYNGGTCEPSTESPYFHCVCPADFNGLLC 1397 HSP 6 Score: 103.99 bits (258), Expect = 5.564e-22 Identity = 127/461 (27.55%), Postives = 194/461 (42.08%), Query Frame = 1
Query: 1708 KCPPGYIGHNCEFNDFCHFISPCEHNCT---TINDN---MVCSCLPGYD----LMPDKKTCKKLECP---KCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQC--FNSK--CICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKC----------DFNNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS---SPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVL----DDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYA-PCDKLRGICYNTYGSFYCQCSSNYV 2961
+CP + G C+F++ C +PC + I DN VC C GY L P C+ C C + KCKCP G+ G C+ + C + C NG GQC F+S C C + G+ C +D+NEC C + C+N GSY+C+C + C+++ C C + + +C C G++G+ C+ +ID+C H+C + CV+ +Y+C C + G+ C E + C + C+NGG C+N++ C C G+ G+ C ++I++C G C + ++ C CPPG L +D K + C+ + +NG + C CP+G+ G C DVDEC A PC+ G C NT GSF C+C YV
Sbjct: 20 RCPEKFWGSACQFSNPC-LPNPCWNGGVCQPVIRDNKVDFVCQCHLGYMDPRCLTPTDNPCRSSPCGNGGTCELTSVRTYKCKCPPGWTGKNCQQ-ADPCASNP----------------CANG-------------------------GQCSPFDSHYICTCTPFFSGETCKQDVNECALSPFPCNNGGVCVNEVGSYRCNCPTEYT----GKHCETLYQPCSPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCP--DHRCLNGGTCVDGVNTYNCQCKPEWT-----GQFCTEDVNECDLMPNSCQNGGTCLNTQGGYNCVCVNGWTGEDCSKNIDDCADAACNVGAT--CHDRVASFFCECPPGRTGLLCHLNDACISNPCQKGSNCDTNPVNG-----KAICTCPLGYFGSACDQDVDECSLGANPCEHA-GKCLNTKGSFQCKCQQGYV 418
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:103042072]) HSP 1 Score: 206.838 bits (525), Expect = 8.356e-54 Identity = 223/720 (30.97%), Postives = 321/720 (44.58%), Query Frame = 1
Query: 1018 KGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDG--KSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDECLFP---VCQQICVNTIGSYQCSCREGFT----LLSNGKCAIN-CLN--NCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECP------------KCVRGTCNENK------------CKCPKGFAGLLCENDINEC-LNQTICQHV--CTNTIGSFFCRCKNGHKLAE---DKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSA---NSHSCQSVCSLCKNG-KC-DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
+ C+NGG C RC C G+ G CQ ++ C R N V G F C CQ GF+ N +C C+ T NC C G++GK C +D+DEC P + IC+NT GS++C C G++ + CA + CLN C++ GD C C G+ G +C +++D+C H C + CV+ ++NCQC +T Q + +C+ + C NGG C C C G+ G +C N I+D C G D+ ECP CV CNE C CP GF G C D++EC + C+H C NT+GSF C+C G+ D C+ N TCLD+ CIC GY G C+ DI+EC+ + + C + ++ C+C GF + + C S + C+NG KC D N +C+C G+ G LC+ +ID C C H CV+ SY+C+C +P Y G C + + C S+PC+NGGKCV+ C+C+ G +G +CE + ++C ++ G C++ Y+C+C PG+ C + + NP C NGG C D C CP GFH C VDEC +PC + G C + C+C +V
Sbjct: 29 RPCENGGMCLDSRCMCRPGYIGPLCQ-HLDPCHRSPCLNGAACKSQVANGVPQFTCVCQRGFRGQNCSLIDACATSPCANGARCTNWNNHYNCSCPPGFQGKNCRNDIDECRKPGKCLNGGICINTHGSFRCECVSGYSGRTCEVPTQPCAPSQCLNGGTCHQTGD-HTYECACLPGFGGTNCEVNVDDCP-GHKCMNGGTCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQP--NACHNGGTCFNTIGGHTCVCVNGWTGDDCSEN---------------IDDCATAVCFNGATCH-DRVASFYCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFIGGACIQDMDECSIGANPCEHFGKCVNTVGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDR------IGEFTCICMPGYTGTHCEIDIDECESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECAS--TPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNC--QPDPCHHGTCVDGIASYTCNC-VPGYT----GYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINYDDCASNPCEY---GMCKDGINRYDCVCKPGFT----GPQCNVELDECSSNP-CRNGGTCVDDENGFHCLCPAGFHEPYCFSHVDECSS-SPC--VHGACREDPDGYRCECEPGWV 701 HSP 2 Score: 205.297 bits (521), Expect = 2.724e-53 Identity = 227/772 (29.40%), Postives = 325/772 (42.10%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTC----FQGR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT----LLSNGKCAINCLNNCNKNGDCLNGI-CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL-----QINKKKCISKSCNIECLNGG----LCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN-CTTINDNMVCSCLPGYDLMP---DKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE---DKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCD-----------FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C C GW G+ C E C +G + R F C C + +T C L+ S C G C GR C C GF G C +++ CS +G CEH CVN +FQC+C G+ + + D C+ C T + C C G+ G C D+DEC C IC + + ++ C+C+ GFT + +CA N K D NG C C G+ G C +ID C+ + CV+ S+ C C G+T Q+N+ C S C NGG L +K C+C G G NCE N +PCE+ C + C C PG+ + C C GTC +++ C CP GF C + ++EC + C + C C+ G D+ C+P N TC+D Q C C+ G+RG +C +INEC + + C++ S+ C C + + +C V + C C F +C C+ GW G LC++D++EC N K + C N+ G Y CSC + G +C + ND +PC +GG C + C C PG+ G C +++ECQ K+G G C + +Y C C PG+ L + T+ + C NGG C D C C +GF G C +V+EC PC G+C + SF C C Y
Sbjct: 276 CVCVNGWTGDDCS----ENIDDCATAVCFNGATCHDRVASFYCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFIGGACIQDMDECS---IGANPCEHFGKCVNT-VGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTHCEIDIDECESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNCQPDPCHHGTCVDGIASYTCNCVPGYTGYRCENQLNE--CHSNPCQ----NGGKCVDLVNKYICQCQHGTSGTNCEINYDDCASNPCEYGMCKDGINRYDCVCKPGFTGPQCNVELDECSSNPCRN--GGTCVDDENGFHCLCPAGFHEPYCFSHVDECSSSPCVHGACREDPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAGTCID------QLNGFTCKCRQGFRGNQCQVNINECASSPCLNQGTCVDGVASFTCLCEAPY----SGPTCAEVLTPCSPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNIDVNECASNPCKNRGTCTNTLGGYVCSCRGGY-----SGPNCETDINDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAIEVDECQSAPCKNG--GTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESS-----CFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDS-QPCLN-GGVCQDGLESFRCSCPKGYT 1007 HSP 3 Score: 204.527 bits (519), Expect = 5.070e-53 Identity = 256/940 (27.23%), Postives = 369/940 (39.26%), Query Frame = 1
Query: 802 CGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLD----FSCICGIKETQNNCLELRTCSKG-CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSR----------------------GQMGNRTCE--------------HICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFP--VCQQ--ICVNTIGSYQCSCREGFT-------------------------------LLSNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN-------CTTINDNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCR---------------------CKNGHKLAEDKRSCI------------PPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSA-NSHSCQSVCSLCKNGKCDFNN---KCKCKTGWTGELCDVDIDECLLNQ------------------------HKCQHN--------------CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS------KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEA 3003
C G+C+ SRC C G+ G C L+P C + C++G + + + F+C+C NC + C+ C NG C C C GF+G C+ +I+ C + RTCE C G++ ++C C GF N + C +C GT V + NC+C W G++C +DV+ECL C C NTIG + C C G+T GK + C N CN+ C LNG IC C +G+ G C D+DEC + CEH CVN GSF CQC G+T +I+ +C+S C + + C C PGY G +CE + I CE N C + + C+C G+ D C C KC+ N +C+C +GF G LCE++I+ C C + I S+ C C+NG K + I N C C +G C + C+CK G+ G +C+ +++EC C++ E + C C GF SH + S C +G C + +C+C+ GW G+ CD+D ++CL N ++CQ N CV+ S++C C P+ G +C E CS +PC N C ++ +C C+PG+ G C D+NEC K+ G C NT G Y C C GY C+ D + NP C++GG C D C C GF G C ++VDECQ APC K G C + S+ C C + ++ T+ M E+
Sbjct: 31 CENGGMCLDSRCMCRPGYIGPLCQHLDP--CHRSP---CLNGAACKSQVANGVPQFTCVCQRGFRGQNCSLIDACATSPCANGARCTNWNNHYNCSCPPGFQGKNCRNDIDECRKPGKCLNGGICINTHGSFRCECVSGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFGGTNCEVNVDDCPGHKCMNGGTCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFYCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFIGGACIQDMDECSIGANPCEHFGKCVNTVGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTHCEID-----IDECESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECASTPCQNGAKCIDRP-NGYECRCAEGFEGRLCESNIDNCQPDPCHHGTCVDGIASYTCNCVPGYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINYDDCASNPCEYGMCKDGINRYDCVCKPGFTGPQCNVELDECSSNPCRNGGTCVDDENGFHCLCPAGFHEPYCFSHVDECSSSPCVHGACREDPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAGTCIDQLNGFTCKCRQGFRGNQCQVNINECASSPCLNQGTCVDGVASFTCLCEAPY-----SGPTCAEVLTPCSPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNIDVNECASNPCKN--RGTCTNTLGGYVCSCRGGY----SGPNCETDINDCLPNP-CMSGGSCTDGINTFYCTCLPGFTGPRCAIEVDECQS-APC-KNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTES 945 HSP 4 Score: 163.696 bits (413), Expect = 2.993e-40 Identity = 227/836 (27.15%), Postives = 336/836 (40.19%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCK----------------QRKLLFCVHGCSFDKRKLDFS--------------------CICGIKETQNNC-LELRTCSKG-CQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-------CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFN-DFCHFISPCEH--NCTTINDNMVCSCLPGYDLM---PDKKTCKKLECPKCVRGTC----NENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGHKLAEDK------RSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYS--------HICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK---------CKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSP--------CKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR------CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYN 2919
IDNC PD HG CV C C G+ G RC E +L + + + C HG S ++++ C+C T C +EL CS C+NGGTC C C GF C ++ CS + C H E + ++C+C+ G+ N D C+ C GT ++ CKC+QG++G C +++EC C Q CV+ + S+ C C ++ + + C N C D C C GW G C++D++EC N C++ C N G + C C G++ N + I+ C++GG C C C PG+ G C D C +PC++ CT ++ C+C PG+ + + C + C GTC N C C GF G C+ ++NEC +Q + VC + + SF C C G+ + + R P N C KD C C G+ G+ CD C+ + +C C+NT ++ C C + S C+S C++ C C+ C G+ G+ C+ +I+EC H CQ+ C++ G Y CSC P + + C D C++P C+N G CV+ +C C PGY GD CE DINEC +C +Y C+C PG+ + CQ P C NGG C C C +G+ G + C+R C +L CYN
Sbjct: 522 IDNCQPDPCHHGTCVDGIASYTCNCVPGYTGYRC---ENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINYDDCASNPCEYGMCKDGINRYDCVCKPGFTGPQCNVELDECSSNPCRNGGTCVDDENGFHCLCPAGFHEPYCFSHVDECS-----SSPCVHGACREDPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAGTCIDQLNGFTCKCRQGFRGNQCQVNINECASSPCLNQGTCVDGVASFTCLCEAPYSGPTCAEVLTPCSPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNIDVNECASNP-CKNRGTCTNTLGGYVCSCRGGYS-GPNCETDINDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAIEVDECQS-APCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFN--GGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQDGLESFRCSCPKGYTGSRCQVRVDWCRHSNPCQNGGRCRPKD--------GSCDCVGGWSGRYCDIPGVSCEMAAMQRGLQTDELCHRGGHCVNTGNTHYCKCPNDYTGSY----CESQVDHCEDKPCLNGATCRGYVGGYTCDCMPGYEGQNCEREINEC--RSHPCQNGGTCIDLVGHYICSCP-PGTMGVL----CEINEDDCATPTRPRGTPKCQNNGTCVDRVGGYRCNCPPGYTGDRCEGDINECHSNPCNAANSLDCIQLPNDYLCVCKPGFT----GRGCQNRFGVCESQP-CKNGGACSGAGSSPLGYICTCQLGYTGTN-------CERSMSCRELS--CYN 1311 HSP 5 Score: 154.066 bits (388), Expect = 2.386e-37 Identity = 204/771 (26.46%), Postives = 293/771 (38.00%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQ---SGFQLDNDGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSC----------------------------------NIECLNGGLCDKD----KCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTINDNMVCSCLPGY------------DLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINEC-----LNQTICQH----------------------------------VCTNTIGSFFCRCKNGH-----KLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHF----CMNTEGSYKCSCMPGFILSA--------NSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK------CKCKPGYNGDSCEEDINECQWP 2643
+D C HG C + RC CE GW G+ C LD +N+CL CQN GTC C+C +GF G+QCQ+ IN C+ N + CV +G +F C C+ SG C CS T + C C+ GW+G CN DV+EC C+ C NT+G Y CSCR G++ + +CL N C G C +GI C C G+ G C++++DEC+ + C++ C + S+ C C GFT + N C SC + CLNGG+C +C CP GY G C+ D+C +PC++ + C C+ G+ ++ ++ + E C RG T N + CKCP + G CE+ ++ C LN C+ C + +G + C C G ++ ED C P + K +G C + +C C GY G RC+ DINEC +S+ C C+ Y C C PGF S C++ + G C C+ G+TG C+ + L+ + V S G+ CSC F RS N SCSS PC+N G C+ C+C G+ G CE++ + P
Sbjct: 672 VDECSSSPCVHGACREDPDGYRCECEPGWVGKNC-------------------------DLD----------RNDCLP-----NPCQNAGTCIDQLNGFTCKCRQGFRGNQCQVNINECASSPCLN---QGTCV-DGVASFTCLCEAPYSGPTCAEVLTPCSPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNIDVNECASNPCKNRGTCTNTLGGYVCSCRGGYSGPNCETDINDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAIEVDECQ-SAPCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQDGLESFRCSCPKGYTGSRCQVRVDWCRHSNPCQNGGRCRPKDGSCDCVGGWSGRYCDIPGVSCEMAAMQRGLQTDEL--CHRGGHCVNTGNTHYCKCPNDYTGSYCESQVDHCEDKPCLNGATCRGYVGGYTCDCMPGYEGQNCEREINECRSHPCQNGGTCIDLVGHYICSCPPGTMGVLCEINEDD--CATPTRPRGTPKCQNNGTCVDRVGGYRCNCPPGYTGDRCEGDINEC--HSNPCNAANSLDCIQLPNDYLCVCKPGFTGRGCQNRFGVCESQPCKNGGACSGAGSSPLGYICTCQLGYTGTNCERSMSCRELSCYNGGSCTVTSRGA-RCSCQQGFAGPQCQHRS----NQSCSSKPCRNNGICIEEANFPFFSCQCMEGWKGKRCEQESRMLERP 1386 HSP 6 Score: 84.3445 bits (207), Expect = 5.429e-16 Identity = 143/567 (25.22%), Postives = 223/567 (39.33%), Query Frame = 1
Query: 781 IDNCVPD-CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCL--ELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSC-SRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCI--------KEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ------------ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG----------ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSG---FTLQINKKKCISKS---CNIECLNGGLCDKD----KCKCPPGYIGHNCEFN-DFCHFISPCEH----NCTTINDNMVCSCLPGY------------DLMPDKK-------------------------------TCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINE------CLNQTICQHVCTNTIGSFFCRCKNGHKLA--EDKRSCIPPNKKTCLDKDCVHGQCFNSKC 2139
I++C+P+ C G C C C G+ G RC I E + C+ C +G + ++C C T +C + C NGGTC C C GF G+ CQ E+N C S+ + C+ +G +F+C C G+ G C C G G+C C GW G++C+ C Q+ CVNT ++ C C +T G + +++C ++ CLNG C C G+ G++C +I+EC+ +H C++ C+++ G + C C G +IN+ C + + +C N G C +C CPPGY G CE + + CH +PC +C + ++ +C C PG+ + P K +C++L C G+C +C C +GFAG C++ N+ C N IC + F C+C G K E + + TCL DC HG+ + C
Sbjct: 863 INDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAI-EVDECQSAP---CKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQ-----DGLESFRCSCPKGYT----GSRCQVRVDWCRHSNPCQNGGRCRPKDGSCDCVGGWSGRYCDIPGVSCEMAAMQRGLQTDELCHRGGHCVNTGNTHYCKCPNDYT----GSYCESQVDHC-EDKPCLNGATCRGYVGGYTCDCMPGYEGQNCEREINECR-SHPCQNGGTCIDLVGHYICSCPPGTMGVLCEINEDDCATPTRPRGTPKCQNNGTCVDRVGGYRCNCPPGYTGDRCEGDINECHS-NPCNAANSLDCIQLPNDYLCVCKPGFTGRGCQNRFGVCESQPCKNGGACSGAGSSPLGYICTCQLGYTGTNCERSMSCRELSCYN--GGSCTVTSRGARCSCQQGFAGPQCQHRSNQSCSSKPCRNNGIC--IEEANFPFFSCQCMEGWKGKRCEQESRMLERPAPTCLIADC-HGKANDGVC 1404
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:103042072]) HSP 1 Score: 203.371 bits (516), Expect = 1.083e-52 Identity = 221/743 (29.74%), Postives = 317/743 (42.66%), Query Frame = 1
Query: 1021 GCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-----QLDNDGKSCIKEECSKFGT--TEVVSGN--CKCKQGWKGKFCNDDVDECLFPV--CQQI--CVNTIGSYQCSCREGFTLLSNGKCAIN---CLN-NCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGC-EHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFN-DFCHFISPCEH-NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE-----DKRSCIP-PNKKTCLDKD---------------------------CVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCD-----------FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C NGGTCF C C G+ GD C I+ C+ N H V +F C+C G LD+ +C+ C++ T ++G C C G+ G C D+DEC C+ CVNT+GS+QC C G+T +C I+ CL+ C + CL+ I C C G+ G C +DIDEC+ N + +C ++ +F C C +GFT QI+ +C S C NG C + +C+C G+ G CE N D C PC H C + C+C+PGY + + C G N+ C+C G +G CE + ++C + +C + I + C CK G + D+ S P N TC+D + CVHG C +C C+ G+ GK CD D N+C C++ + C C GF +C V + C C F +C C+ GW G LC++D++EC N K + C N+ G Y CSC + G +C + ND +PC +GG C + C C PG+ G C +++ECQ K+G G C + +Y C C PG+ L + T+ + C NGG C D C C +GF G C +V+EC PC G+C + SF C C Y
Sbjct: 201 ACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVA----SFYCECPVGKTGLLCHLDD---ACVSNPCNEGAVCDTNPLNGRAICTCPAGFIGGACIQDMDECSIGANPCEHFGKCVNTVGSFQCQCGRGYT---GPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTHCEIDIDECESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECASTPCQ----NGAKCIDRPNGYECRCAEGFEGRLCESNIDNCQ-PDPCHHGTCVDGIASYTCNCVPGYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINYDDCASNPCEYGMCKDGINRYDCVCKPGFTGPQCNVELDECSSNPCRNGGTCVDDENGFHCLCPAGFHEPYCFSHVDECSSSPCVHGACREDPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAGTCIDQLNGFTCKCRQGF--RGGGPTCAEVLTPCSPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNIDVNECASNPCKNRGTCTNTLGGYVCSCRGGY-----SGPNCETDINDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAIEVDECQSAPCKNG--GTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESS-----CFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDS-QPCLN-GGVCQDGLESFRCSCPKGYT 912 HSP 2 Score: 180.259 bits (456), Expect = 1.619e-45 Identity = 216/727 (29.71%), Postives = 311/727 (42.78%), Query Frame = 1
Query: 985 QNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFP---VCQQICVNTIGSYQCSCREGFT----LLSNGKCAIN-CLN--NCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECP------------KCVRGTCNENK------------CKCPKGFAGLLCENDINEC-LNQTICQHV--CTNTIGSFFCRCKNGHKLAE---DKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSA---NSHSCQSVCSLCKNG-KC-DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQH-NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
++ CL C NG F C C GF G C L I++C+ N C N N++ C C GFQ GK C +D+DEC P + IC+NT GS++C C G++ + CA + CLN C++ GD C C G+ G +C +++D+C H C + CV+ ++NCQC +T Q + +C+ + C NGG C C C G+ G +C N I+D C G D+ ECP CV CNE C CP GF G C D++EC + C+H C NT+GSF C+C G+ D C+ N TCLD+ CIC GY G C+ DI+EC+ + + C + ++ C+C GF + + C S + C+NG KC D N +C+C G+ G LC+ +ID C C H CV+ SY+C+C +P Y G C + + C S+PC+NGGKCV+ C+C+ G +G +CE + ++C ++ G C++ Y+C+C PG+ C + + NP C NGG C D C CP GFH C VDEC +PC + G C + C+C +V
Sbjct: 2 RSPCLNGAACKSQVANGVPQFT--CVCQRGFRGQNCSL-IDACATSPCANGA---RCTNW-NNHYNCSCPPGFQ---------------------------------GKNCRNDIDECRKPGKCLNGGICINTHGSFRCECVSGYSGRTCEVPTQPCAPSQCLNGGTCHQTGD-HTYECACLPGFGGTNCEVNVDDCP-GHKCMNGGTCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQP--NACHNGGTCFNTIGGHTCVCVNGWTGDDCSEN---------------IDDCATAVCFNGATCH-DRVASFYCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFIGGACIQDMDECSIGANPCEHFGKCVNTVGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLDR------IGEFTCICMPGYTGTHCEIDIDECESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECAS--TPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNC--QPDPCHHGTCVDGIASYTCNC-VPGYT----GYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINYDDCASNPCEY---GMCKDGINRYDCVCKPGFT----GPQCNVELDECSSNP-CRNGGTCVDDENGFHCLCPAGFHEPYCFSHVDECSS-SPC--VHGACREDPDGYRCECEPGWV 642 HSP 3 Score: 162.54 bits (410), Expect = 5.481e-40 Identity = 236/835 (28.26%), Postives = 333/835 (39.88%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPEL--CKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLD---NDGKSCIKEECSKFGTTEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG-----------DCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFN-DFCHFISPCEH--NCTTINDNMVCSCLPGYDLM---PDKKTCKKLECPKCVRGTC----NENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGHKLAEDK------RSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYS------HICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK---------CKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSP--------CKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYL---------VLDDQK-----TCQISTKDTMCNP-------HCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYN--TYGSFYCQCSSNY 2958
IDNC PD HG CV C C G+ G RC E +L C C +G + C C + NC + C+ G C G C C GF G QC +E++ CS N CV++ EN F C C +GF + C C E G C+C+ GW GK C+ D ++CL CQ C++ + + C CR+GF G L C+ N D C C GW G C++D++EC N C++ C N G + C C G++ N + I+ C++GG C C C PG+ G C D C +PC++ CT ++ C+C PG+ + + C + C GTC N C C GF G C+ ++NEC +Q + VC + + SF C C G+ + + R P N C KD C C G+ G+ CD C+ + +C C+NT ++ C C + S C+S C++ C C+ C G+ G+ C+ +I+EC H CQ+ C++ G Y CSC P + + C D C++P C+N G CV+ +C C PGY GD CE DINEC +C +Y C+C PG+ V + Q C T C C NGG C S RC C GF G C ++ PC + GIC + F CQC +
Sbjct: 463 IDNCQPDPCHHGTCVDGIASYTCNCVPGYTGYRC---ENQLNECHSNP---CQNGGKCVDLVNKYICQCQHGTSGTNCEINYDDCASNPCEYGMCKDGINRYDCVCKPGFTGPQCNVELDECSSNPCRNGG---TCVDD-ENGFHCLCPAGFHEPYCFSHVDECSSSPCVHGACREDPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAGTCIDQLNGFTCKCRQGFR--GGGPTCAEVLTPCSPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNIDVNECASNP-CKNRGTCTNTLGGYVCSCRGGYS-GPNCETDINDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAIEVDECQS-APCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFN--GGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQDGLESFRCSCPKGYTGSRCQVRVDWCRHSNPCQNGGRCRPKD--------GSCDCVGGWSGRYCDIPGVSCEMAAMQRGLYELCHRGGHCVNTGNTHYCKCPNDYTGSY----CESQVDHCEDKPCLNGATCRGYVGGYTCDCMPGYEGQNCEREINEC--RSHPCQNGGTCIDLVGHYICSCP-PGTMGVL----CEINEDDCATPTRPRGTPKCQNNGTCVDRVGGYRCNCPPGYTGDRCEGDINECHSNPCNAANSLDCIQLPNDYLCVCKPGFTGRGCQNRFGVCESQPCKNGGACSGGYTGTNCERSMSCRELSCYNGGSCTVTSRGARCSCQQGFAGPQCQHRSNQSCSSKPC-RNNGICIEEANFPFFSCQCMEGW 1260 HSP 4 Score: 149.058 bits (375), Expect = 9.484e-36 Identity = 202/767 (26.34%), Postives = 304/767 (39.63%), Query Frame = 1
Query: 784 DNCVPDCGEHGICV----KSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCL-ELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIK-------EECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSC----------------------------------NIECLNGGLCDKD----KCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTINDNMVCSCLPGY------------DLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINEC-----LNQTICQH----------------------------------VCTNTIGSFFCRCKNGH-----KLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHF----CMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK------CKCKPGYNGDSCEEDINECQWP 2643
D+C + E+G+C + C C+ G+ G +C + E + C C +G + + F C+C + C + CS G C + RC+C G+ G C L+ N C N C+++ N F CKC+ GF+ G +C + CS T + C C+ GW+G CN DV+EC C+ C NT+G Y CSCR G++ + +CL N C G C +GI C C G+ G C++++DEC+ + C++ C + S+ C C GFT + N C SC + CLNGG+C +C CP GY G C+ D+C +PC++ + C C+ G+ ++ ++ +L C RG T N + CKCP + G CE+ ++ C LN C+ C + +G + C C G ++ ED C P + K +G C + +C C GY G RC+ DINEC +S+ C C+ Y C C PGF CQ+ +C++ C N C G+TG C+ + L+ + V S G+ CSC F RS N SCSS PC+N G C+ C+C G+ G CE++ + P
Sbjct: 539 DDCASNPCEYGMCKDGINRYDCVCKPGFTGPQCNV-ELDECSSNP---CRNGGTCVDDENGFHCLCPAGFHEPYCFSHVDECSSSPCVHGACREDPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAG---TCIDQ-LNGFTCKCRQGFR--GGGPTCAEVLTPCSPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNIDVNECASNPCKNRGTCTNTLGGYVCSCRGGYSGPNCETDINDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAIEVDECQ-SAPCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQDGLESFRCSCPKGYTGSRCQVRVDWCRHSNPCQNGGRCRPKDGSCDCVGGWSGRYCDIPGVSCEMAAMQRGLYEL----CHRGGHCVNTGNTHYCKCPNDYTGSYCESQVDHCEDKPCLNGATCRGYVGGYTCDCMPGYEGQNCEREINECRSHPCQNGGTCIDLVGHYICSCPPGTMGVLCEINEDD--CATPTRPRGTPKCQNNGTCVDRVGGYRCNCPPGYTGDRCEGDINEC--HSNPCNAANSLDCIQLPNDYLCVCKPGFT----GRGCQNRFGVCESQPC--KNGGACSGGYTGTNCERSMSCRELSCYNGGSCTVTSRGA-RCSCQQGFAGPQCQHRS----NQSCSSKPCRNNGICIEEANFPFFSCQCMEGWKGKRCEQESRMLERP 1275 HSP 5 Score: 96.2857 bits (238), Expect = 1.147e-19 Identity = 143/550 (26.00%), Postives = 228/550 (41.45%), Query Frame = 1
Query: 781 IDNCVPD-CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCL--ELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSC-SRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCI--------KEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDEC--------LFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG----------ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSG---FTLQINKKKCISKS---CNIECLNGGLCDKD----KCKCPPGYIGHNCEFN-DFCHFISPCEH----NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCK----CPKGFAGLLCENDIN----ECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVH-GQCFNSK------CICKSGYRGKRCDEDINECKKYSHIC 2214
I++C+P+ C G C C C G+ G RC I E + C+ C +G + ++C C T +C + C NGGTC C C GF G+ CQ E+N C S+ + C+ +G +F+C C G+ G C C G G+C C GW G++C+ C L+ +C + CVNT ++ C C +T G + +++C ++ CLNG C C G+ G++C +I+EC+ +H C++ C+++ G + C C G +IN+ C + + +C N G C +C CPPGY G CE + + CH +PC +C + ++ +C C PG+ + C+ G C CK C G+ G CE ++ C N CT T C C+ G + C + ++C K C + G C C C G++GKRC+++ ++ + C
Sbjct: 768 INDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAI-EVDECQSAP---CKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQ-----DGLESFRCSCPKGYT----GSRCQVRVDWCRHSNPCQNGGRCRPKDGSCDCVGGWSGRYCDIPGVSCEMAAMQRGLYELCHRGGHCVNTGNTHYCKCPNDYT----GSYCESQVDHC-EDKPCLNGATCRGYVGGYTCDCMPGYEGQNCEREINECR-SHPCQNGGTCIDLVGHYICSCPPGTMGVLCEINEDDCATPTRPRGTPKCQNNGTCVDRVGGYRCNCPPGYTGDRCEGDINECHS-NPCNAANSLDCIQLPNDYLCVCKPGFT----GRGCQNR------FGVCESQPCKNGGACSGGYTGTNCERSMSCRELSCYNGG----SCTVTSRGARCSCQQGFAGPQ----CQHRSNQSCSSKPCRNNGICIEEANFPFFSCQCMEGWKGKRCEQESRMLERPAPTC 1279
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002704.1 (pep scaffold:Pmarinus_7.0:GL476354:513769:588114:-1 gene:ENSPMAG00000002318.1 transcript:ENSPMAT00000002704.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 163.31 bits (412), Expect = 7.249e-41 Identity = 231/801 (28.84%), Postives = 322/801 (40.20%), Query Frame = 1
Query: 1153 CVNEGENNFQCKCQSGFQLDNDGKSCIK-EECSKFGT-------TEVVSGNCKCKQGW----KGKFCNDDVDEC-LFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYC-FSGWH--------------GEDC-----------------------SLDIDECKYNHG--CEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIEC-LNGGLCDKDKCK---------CPPGYI----GHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTC----NENKCK--------------------------------CPKGFA---GLLCENDINEC-LNQTICQHV-CTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTC----------------LDKD---CVHGQCFNSKC-------------ICKSGYR--------GKRCDEDINECKKYSHICEHF-CMNTEGSYKCSCMPGFILSANSHSCQSV------CSLCKNGKC---DFNNKCKCKTGWTGELCD----VDIDECLLNQHKCQ-HNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS---SPCKNGGKCVNS----KCKCKPGYNGDSCEE---DINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDK-----LRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPH 3018
CVN E +FQC C +GF+L DG++C+ +ECS E S C CK G+ G++C D+DEC +C C+NT GS++C C G + +G+ I+ GD + G C F G + GE C DI+EC N C N G++ C C+ G+ I KKC+ EC L LCD C+ CP GY+ CE D C NC + C CLP L K C + +GTC +N+C+ CPKGF+ G CE D+NEC + IC + C NT GSF C C GH L R+CI + C L D C G+ + +C +C G G+ +DINECK + +C + C NT GS+KC+C GF+L A +C + +C G C + C+C G+ +DIDEC N C+ CVN+ GS+ C C P + DG CL+ D CS + C+N G+CVN +C C GY+ + DI+EC I GC C N+ G+YEC C GY +L D ++C + NP+ +GG C ++ Y + + G VD+ C C+ + G C NT GSF C C + + T C + E + H
Sbjct: 488 CVNT-EGSFQCICNAGFELTADGRNCLDHDECSTTNMCLNGMCINEDGSFKCICKPGFYLVPSGRYCL-DIDECQTHGICMNGRCINTEGSFKCECPPGMIVSMDGRLCIDTHMRSTCYGDYMMGKCLTPFPGANTKSECCCANPNFAFGEPCLPCPAVNSDDYKMLCPTPGFDNGGKDINECALNPEICTNGQCENQLGTYRCVCNIGYESDITGKKCVDVD---ECMLRAHLCDNGSCRNTPGSYTCACPAGYLFKHETEMCEDVDECESNPCINGNCQNTVGSFTCVCLPTSKLDQTKTICIES-----TKGTCWLNIIDNRCEVNVNGATLKSECCSTLGAAWGSPCEPCELDTICPKGFSRAKGTQCE-DVNECEVFAGICVNSRCINTAGSFKCECPPGHTLESTGRTCIDLRLENCYLSYEEEECEEPLAVRLRSDVCCCSLGKAWGPECEGCPEKGSSEYAFLCPRGPGYSNRGDPVGRHFFKDINECKVFPQMCSNGKCRNTIGSFKCNCENGFVLDAEGKNCTDIDECKISHDICGMGTCVNTPGSFDCECMEGFESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFKCLC-PPGHDLNEDGTVCLDV-DECSLSGNLCRN-GRCVNMIGSYQCSCNTGYSATPDRQGCVDIDECT--IMNGGCDTHCSNSDGSYECSCERGYALLPDTRSCS-DIDECEDNPYLCDGGQCTNVPGEYRCLCYDGFISSVDMKTCSDVNECELNPNICIHGKCENTRGSFICHCKVGFTVKKGSTGCTDVDECEIGAH 1271 HSP 2 Score: 156.762 bits (395), Expect = 8.625e-39 Identity = 184/639 (28.79%), Postives = 268/639 (41.94%), Query Frame = 1
Query: 1324 DVDEC-LFP-VCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGC--EHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQH-VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYR---GKRCDEDINECKKYSHICEHF-CMNTEGSYKCSCMPGFILSANSHSCQSV--CSL----CKNGKCDFNNK---CKCKTGWT---GELCDVDIDECLLNQHKC--QHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKN---GGKCVNS----KCKCKPGYNGDS--------CEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGV--CRDMSRCYCPIGFHGIDCG---VDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGNKGVTKVIEN*FGILNAS 3093
D++EC +FP +C C NTIGS++C+C GF L + GK NC DIDECK +H CVN PGSF+C+C GF K C++ C+++ C G C + C C PG+DL D C D++EC L+ +C++ C N IGS+ C C G+ D++ C+ ++ T ++ C C NS +C C+ GY R DI+EC+ ++C+ C N G Y+C C GFI S + +C V C L C +GKC+ C CK G+T G D+DEC + H C C N GS+ C+C ++ DG C + D C++ N KCVN C C+ G++GD C E++N C++ G+C N+ G Y C C G++ D ++C+ + M + C+ G M RC C G+ + G D DEC + C GIC NT GSF C C ++Y + G C+ V K L RG+ ++ +E GI +S
Sbjct: 968 DINECKVFPQMCSNGKCRNTIGSFKCNCENGFVLDAEGK-------NCT-----------------------DIDECKISHDICGMGTCVNTPGSFDCECMEGFESGFMMMK--------NCMDIDECERNPLLCRGG--------------------TCVNTEGSFKCLCPPGHDLNEDGTVCL------------------------------DVDECSLSGNLCRNGRCVNMIGSYQCSCNTGYSATPDRQGCVDIDECTIMNGGC-DTHCSNSDGSYECSCERGYALLPDTRSCSDIDECEDNPYLCDGGQCTNVPGEYRCLCYDGFISSVDMKTCSDVNECELNPNICIHGKCENTRGSFICHCKVGFTVKKGSTGCTDVDECEIGAHNCDMHATCANVQGSFKCTCIEGYF---GDGVKC-QDVDECANGTHNCIPEAKCVNIPGTFTCVCRDGFSGDGQTCVDMDECAENVNLCEF--------GQCLNSAGGYRCECEMGFVPTVDGRSCK-DIDECMFDNICVFGKCENVPGMFRCVCDPGYEIDETGGNCTDKDECADPSNC--FNGICTNTQGSFLCTCPADYQMSPSGQGCVGTDYRVGKCFLESTERGDGTLSCNVEIGIGISRSS 1502 HSP 3 Score: 142.124 bits (357), Expect = 2.689e-34 Identity = 230/832 (27.64%), Postives = 328/832 (39.42%), Query Frame = 1
Query: 1000 ELRTCSKGCQNGGTCFQG----RCQCTEGF---------EGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIK-EECSKF----GT--TEVVSGNCKCKQGWKGKFCND--DVDECL---FPVCQ-QICVNTIGSYQCSCREGFTLLSNGKCAINC--LNNCNK-NGDCLNGIC---------YCFSGWH-GEDCSLDIDECKYNHGCEHL--CVNVPGSFNCQCHSGFTLQINKKK--------CISKSCNIECLNGGLCDKDKCKC-----PPGYIGHNCE----------FNDFCHF--------------ISPCEHN--------CTTINDNMVCSCLPGYDLMPDKKTCKKL-ECP---KCVRGTC----NENKCKCPKGF--AGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNK-----KTCLDKDCVHGQCFNS-KCICKSGYRGKRCDE---DINECKKYSHICEH-FCMNTEGSYKCSCMPGFILSANSHSC-------------QSVCSLCKNGKCDFNNKCKC----KTGWTGELCDV------------------------DIDECLLNQHKCQH-NCVNSNGSYSCSCNLPFYLST-----VDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGY----NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP-HCLNGGVCRDMS---RCYCPIGFHGIDCGV---DVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
E + K CQ C RC+C+ G+ + D+C + CS G+ + E +++C C +G++ D C+ +EC + GT V S NC C G++ ND D DEC+ VC+ C+N +GS++C C EGF L ++ K NC +N C + G C G C C G+ E+ DIDEC + C+N GSF C+C SGF L +K C S+ +C + K C P G CE + C + + C N C + + C C GY+L C EC C GTC +C C GF ++ D+NEC LN +C C N GS+ C C G+ L ED+R C ++ C ++ + + CIC GY + E D NEC+ ICE+ C+N GSYKC C GF L+ + C QS+C + + + + K +C GW G+ CD+ DIDEC + C H C+NS GSY C CN + VD C + C+ CKN + +C C GY +G +C D++EC +H C C NT G + C CPPG+ T I + + P C + GVC++ C C GF + G D+DEC C C N G + C C S Y+ + C+ E
Sbjct: 1751 ECASAEKMCQRNAECINSVGSYRCECSPGYTQTPFGLCIDRDECSEKPEICSPGR----------CQDTEGSYRCMCPNGYKATEDQNMCMDVDECERQPCGNGTCRNTVGSFNCLCFPGFEISANNDCMDKDECVSLAAHVCKFGSCINNVGSFKCLCNEGFELTADKK---NCRDINECQQFRGMCAPGTCQNLEGSFRCMCPPGYEVKEEACTDIDECSSEEDLCMMGSCLNTFGSFECRCPSGFILSETGRKCYDVRVNYCFSEFAQGKCSTPKPFNTSKAGCCCSMMPGDGWGDPCEPCPKQNEEEAYRLLCPYGPGTVVGRDDSREDLDECLANPGICANGRCINTDGSFRCDCPMGYNLEAAGFKCVDANECSIGNPCGNGTCLNVPGGFECTCDDGFEPGPMMTCEDLNECSLNPLLCAFRCVNNFGSYECMCPTGYVLREDRRMCKDQDECEEGLDNCASRNMICKNLIGTYMCICPPGYTRRPDGEGCIDENECRLKPGICENGRCINNVGSYKCVCNEGFTLNQDETECVDSRRGFCFTEVIQSLCQMVSSSR-NLVTKSECCCDGGRGW-GQQCDICPLPGTAQYKKLCPHGPGYTTDGRDIDECTVMPGMCHHGQCINSEGSYHCMCNNGYTTDITRTGCVDLDECAQSPKPCNFICKNTEG--SYQCACPRGYIMQEDGRTCR-DLDECAS--KQHNCQFLCVNTIGGFTCKCPPGFT---QHHTACIDNNECVSQPGTCGSKGVCQNSPGSFSCECQKGFSLDNSGSNCEDMDECSGNHRCQHG---CQNMLGGYRCGCPSGYLQHFQWNQCVDENE 2556 HSP 4 Score: 141.354 bits (355), Expect = 4.334e-34 Identity = 173/596 (29.03%), Postives = 238/596 (39.93%), Query Frame = 1
Query: 1528 LDIDECKYNHG--CEHLCVNVPGSFNCQCHSGFTL--------QINKKKCISKSC--NIECLNGGLCDKDKCKCPPGYIGHN---CEFNDFC----HFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDI-----NECLNQ----TICQHVC-----TNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCD-EDINECKKYSHICEH-FCMNTEGSYKCSCMPGFILSANSHSCQSV-----CSLCKNGKCD----FNNK---CKCKT----GWTGELCDV-----------------------------DIDECLLNQHKCQHN-CVNSNGSYSCSCNLPFYLSTVDGRSCLEKND-SCSSPCKNGGKCVNS----KCKCKPGYNGDSCE--EDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQR-YAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGR 3036
+DIDEC G +CVN+PGSF C+C GF IN+ K C N EC+N +C+C PGY C D C SP C + C C GY D+ C ++ +C R C C+ G LC N+C+++ ++ HVC N +GSF C C G +L DK++C N+ C G C N +C+C GY K DI+EC +C C+NT GS++C C GFILS C V S GKC FN C C GW G+ C+ D+DECL N C + C+N++GS+ C C + + L G C++ N+ S +PC NG C+N +C C G+ ED+NEC ++ C C N FG+YEC+CP GY++ +D++ C+ D DEC+ C IC N G++ C C Y DG C+ E LKP + GR
Sbjct: 1705 IDIDECSKIQGICTNGMCVNLPGSFRCECPMGFLYNDIQIICEDINECASAEKMCQRNAECINS--VGSYRCECSPGYTQTPFGLCIDRDECSEKPEICSP--GRCQDTEGSYRCMCPNGYKATEDQNMCMDVD--ECERQPCGNGTCRNTVGSFNCLCFPGFEISANNDCMDKDECVSLAAHVCKFGSCINNVGSFKCLCNEGFELTADKKNCRDINECQQFRGMCAPGTCQNLEGSFRCMCPPGYEVKEEACTDIDECSSEEDLCMMGSCLNTFGSFECRCPSGFILSETGRKCYDVRVNYCFSEFAQGKCSTPKPFNTSKAGCCCSMMPGDGW-GDPCEPCPKQNEEEAYRLLCPYGPGTVVGRDDSREDLDECLANPGICANGRCINTDGSFRCDCPMGYNLEAA-GFKCVDANECSIGNPCGNG-TCLNVPGGFECTCDDGFEPGPMMTCEDLNECS--LNPLLCAFRCVNNFGSYECMCPTGYVLREDRRMCK-------------------------------------DQDECEEGLDNCASRNMICKNLIGTYMCICPPGYTRRPDGEGCIDENECRLKPGICENGR 2252 HSP 5 Score: 138.658 bits (348), Expect = 3.263e-33 Identity = 207/736 (28.12%), Postives = 302/736 (41.03%), Query Frame = 1
Query: 1324 DVDECLF--PVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN--CNKNGDCLNGI---------CYCFSGWH----GEDCSLDIDECKYNHGCEH-LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHN-----CEFNDFCHFISPCEHNCTTINDN---MVCSCLPGYD--------LMPDKKTCKKLECP---------------------KCV-----------------RGTCNENKCKCPKGF----AGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTC----LDKDC---VHGQCFNSKC-------------------ICKSGY---RGKRCDEDINECKKYSHICEHF-CMNTEGSYKCSCMPGFILSANSHSCQSV----------------------------CSLCK-----------NGKCDFNNKCKCKTGWTGELCDV------DIDECLLNQHKCQHN-CVNSNGSYSCSCNLPFYLSTVDGRSCLEKND-SCSSPCKNGGKCVNSK----CKCKPGYNGDSCE----EDINECQW-PISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCG---VDVDECQRY-APCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHL 3021
D+DEC++ VC+ CVNT GS+QC C GF L ++G+ NCL++ C+ CLNG+ C C G++ G C LDIDEC+ + C + C+N GSF C+C G + ++ + CI C D KC + G N C N F PC C +N + M+C PG+D + + C +C KCV R T C CP G+ +CE D++EC + C NT+GSF C C KL + K CI K TC +D C V+G S+C IC G+ +G +C ED+NEC+ ++ IC + C+NT GS+KC C PG L + +C + CSL K G ++ C G++ V DI+EC + C + C N+ GS+ C+C F L +G++C + ++ S G CVN+ C+C G+ DI+EC+ P+ G G C NT G+++C+CPPG+ + +D C + ++ C N G C +M +C C G+ VD+DEC CD C N+ GS+ C C Y L+ D SC + E P+L
Sbjct: 472 DIDECVYNGQVCKNGRCVNTEGSFQCICNAGFELTADGR---NCLDHDECSTTNMCLNGMCINEDGSFKCICKPGFYLVPSGRYC-LDIDECQTHGICMNGRCINTEGSFKCECPPGMIVSMDGRLCIDTHMRSTCYG----DYMMGKCLTPFPGANTKSECCCANPNFAFGEPC-LPCPAVNSDDYKMLCP-TPGFDNGGKDINECALNPEICTNGQCENQLGTYRCVCNIGYESDITGKKCVDVDECMLRAHLCDNGSCRNTPGSYTCACPAGYLFKHETEMCE-DVDECESNPCINGNCQNTVGSFTCVCLPTSKLDQTKTICIESTKGTCWLNIIDNRCEVNVNGATLKSECCSTLGAAWGSPCEPCELDTICPKGFSRAKGTQC-EDVNECEVFAGICVNSRCINTAGSFKCECPPGHTLESTGRTCIDLRLENCYLSYEEEECEEPLAVRLRSDVCCCSLGKAWGPECEGCPEKGSSEYAFLCPRGPGYSNRGDPVGRHFFKDINECKVFPQMCSNGKCRNTIGSFKCNCENGFVLD-AEGKNCTDIDECKISHDICGMGTCVNTPGSFDCECMEGFESGFMMMKNCMDIDECERNPLLCRG--GTCVNTEGSFKCLCPPGHDLNEDGTVCLDVDECSLSGNLCRN-GRCVNMIGSYQCSCNTGYSATPDRQGCVDIDECTIMNGGCDTH---CSNSDGSYECSCERGYALLPDTRSCSDIDECEDNPYL 1188 HSP 6 Score: 132.494 bits (332), Expect = 2.568e-31 Identity = 216/819 (26.37%), Postives = 306/819 (37.36%), Query Frame = 1
Query: 955 FSCICG----IKETQNNCLELRTCS--KGCQNGGTC--FQG--RCQCTEGFEG--------DQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSC------------IKEECSKFGTTEVVSGNCKCKQ----GWKGKFCN-----------------------------DDVDECLF--PVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCS-----------LDIDECKYNHG-CEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCK-----KLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLN-----------QTICQHVCT--NTIGSFFCRCKNGHKLAEDKRSCIPPNKK----------------------TCLDKDCVHGQCFNSK----CICKSGYRGKRCDE---DINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSP--CKNGGKCVNS----KCKCKPGYNGDSCE---EDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIG--FHGIDCGV-DVDECQRY-APCDKLRGICYNTYGSFYCQCSSNYVLMYDG 2976
F C+C + + NC ++ C +G GTC +G RC C G+E D+C E + C G C+N +F+C+C SGF L G+ C + +CS C C GW G C +D+DECL +C C+NT GS++C C G+ L + G ++ N C+ C NG C G C D++EC N C CVN GS+ C C +G+ L+ +++ C KD+ +C G NC + C + +C C PGY PD + C +L+ C G C N KC C +GF D EC++ Q++CQ V + N + C C G + C P T + C HGQC NS+ C+C +GY D++EC + C C NTEGSY+C+C G+I+ + +C+ D+DEC QH CQ CVN+ G ++C C F T +C++ N+ S P C + G C NS C+C+ G++ D+ ED++EC H C C+N G Y C CP GYL C + T NP C + +C CP G F G DV+EC APC+ C NT G + C C Y G
Sbjct: 1895 FKCLCNEGFELTADKKNCRDINECQQFRGMCAPGTCQNLEGSFRCMCPPGYEVKEEACTDIDECSSEEDLCMMGS---------CLNT-FGSFECRCPSGFILSETGRKCYDVRVNYCFSEFAQGKCSTPKPFNTSKAGCCCSMMPGDGW-GDPCEPCPKQNEEEAYRLLCPYGPGTVVGRDDSREDLDECLANPGICANGRCINTDGSFRCDCPMGYNLEAAGFKCVD-ANECSIGNPCGNGTCLNVPGGFECTCDDGFEPGPMMTCEDLNECSLNPLLCAFRCVNNFGSYECMCPTGYVLREDRRMC----------------KDQDECEEGL--DNCASRNMI---------CKNLIGTYMCICPPGYTRRPDGEGCIDENECRLKPGICENGRCINNVGSYKCVCNEGFT---LNQDETECVDSRRGFCFTEVIQSLCQMVSSSRNLVTKSECCCDGGRGWGQQCDICPLPGTAQYKKLCPHGPGYTTDGRDIDECTVMPGMCHHGQCINSEGSYHCMCNNGYTTDITRTGCVDLDECAQSPKPCNFICKNTEGSYQCACPRGYIMQEDGRTCR------------------------------DLDECASKQHNCQFLCVNTIGGFTCKCPPGF---TQHHTACIDNNECVSQPGTCGSKGVCQNSPGSFSCECQKGFSLDNSGSNCEDMDECS---GNHRCQHGCQNMLGGYRCGCPSGYLQHFQWNQCVDENECT--NPQVCGSASCYNTLGSFKCACPNGYNFDQFSGGCNDVNECSHSKAPCNFG---CSNTEGGYLCGCPPGYFRAGQG 2630 HSP 7 Score: 129.413 bits (324), Expect = 1.910e-30 Identity = 226/853 (26.49%), Postives = 312/853 (36.58%), Query Frame = 1
Query: 793 VPDCGEHGICVKSRCYCETGWFGERC-----VILEPELCKQRKLLFCVHG--------CSFDKRKLDFSCICG------------IKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIK-EECS------KFGTTEVVSGN--CKCKQGWKGKFCN---DDVDECLF-PVCQQICVNTIGSYQCSCREGFTL---------LSNGKCAINCLNN---CNKNGDCLNGIC--YCFSGWHG--EDCSL-----------------DIDECKYNHG--CEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFA--------GLLCENDINEC--LNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSK----CICKSGYRG-----KRCDEDINECKKYSHICE-HFCMNTEGSYKCSCMPGFILSANSHSCQSV--CS----LCKNGKC---DFNNKCKCKTGWTGELCD---VDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVC---RDMSRCYCPIGF---HGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPH 3018
+ +C HGIC+ RC G F C V ++ LC + +G F C C ++ ++ + G NGG + ++C L C+ GQ N+ ++C C G++ D GK C+ +EC G+ G+ C C G+ K +DVDEC P C NT+GS+ C C L + G C +N ++N N NG L C + W E C L D++EC+ G C+N GSF C+C G TL+ + CI NC + + CE + VC C G P EC C +E CP+G G DINEC Q C NTIGSF C C+NG L + ++C ++ C G C N+ C C G+ K C DI+EC++ +C C+NTEGS+KC C PG L+ + C V CS LC+NG+C + +C C TG++ VDIDEC + C +C NS+GSY CSC + L D RSC + D CE++ C G+C N G Y C+C G++ D KTC + NP+ G C R C+C +GF G DVDEC+ A + C N GSF C C Y DG C + E H
Sbjct: 556 IDECQTHGICMNGRCINTEGSFKCECPPGMIVSMDGRLCIDTHMRSTCYGDYMMGKCLTPFPGANTKSECCCANPNFAFGEPCLPCPAVNSDDYKMLCPTPGFDNGGK------------DINECALNPEICTNGQCENQL----------GTYRCVCNIGYESDITGKKCVDVDECMLRAHLCDNGSCRNTPGSYTCACPAGYLFKHETEMCEDVDECESNPCINGNCQNTVGSFTCVCLPTSKLDQTKTICIESTKGTCWLNIIDNRCEVNVNGATLKSECCSTLGAAWGSPCEPCELDTICPKGFSRAKGTQCEDVNECEVFAGICVNSRCINTAGSFKCECPPGHTLESTGRTCIDLRL-----------------------ENCYLS---YEEEECEEPLAVRLRSDVCCCSLGKAWGP--------ECEGCPEKGSSEYAFLCPRGPGYSNRGDPVGRHFFKDINECKVFPQMCSNGKCRNTIGSFKCNCENGFVLDAEGKNCTDIDECKISHDICGMGTCVNTPGSFDCECMEGFESGFMMMKNC-MDIDECERNPLLCRGGTCVNTEGSFKCLCPPGHDLNEDGTVCLDVDECSLSGNLCRNGRCVNMIGSYQCSCNTGYSATPDRQGCVDIDECTIMNGGCDTHCSNSDGSYECSCERGYAL-LPDTRSCSDI---------------------------DECEDNPYLCDG--------GQCTNVPGEYRCLCYDGFISSVDMKTCS-DVNECELNPNICIHGKCENTRGSFICHCKVGFTVKKGSTGCTDVDECEIGAHNCDMHATCANVQGSFKCTCIEGY--FGDGVKCQDVDECANGTH 1312 HSP 8 Score: 127.102 bits (318), Expect = 9.523e-30 Identity = 189/747 (25.30%), Postives = 297/747 (39.76%), Query Frame = 1
Query: 1174 NFQCKCQSGFQLDNDGKSC-------IKEECSKFGTTEVVSG--NCKCKQGWKGKFCND----DVDECLF--PVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCIS-KSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKL-ECPK----CVRGTCN----ENKCKCPKGF---AGLLCENDINEC-LNQTICQH-VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDC-VHGQCFNS----KCICKSGYRG-----KRCDE-------------------------------------DINECKKYSHICEHF-CMNTEGSYKCSCMPGFILSANSHSCQSVC-----SLCKNGKCD---FNNKCKCKTGW----TGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCL--------------EKND-------------SCSSPCKNGGKCVNSKCKCKPGYNGDSCE------------------EDINEC-QWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEA 3003
+F+C C++GF LD +GK+C I + GT G +C+C +G++ F D+DEC +C+ CVNT GS++C C G L +G ++ ++CSL + C+ CVN+ GS+ C C++G++ +++ C+ C I +NGG C+ +C+ + + CSC GY L+PD ++C + EC C G C E +C C GF + +D+NEC LN IC H C NT GSF C CK G + + C ++ +C +H C N KC C GY G + DE D++EC + ++CE C+N+ G Y+C C GF+ + + SC+ + ++C GKC+ +C C G+ TG C D DEC + C N+ GS+ C+C + +S G+ C+ E+ D S SS C + G+ + C+ P N EDI+EC + P G G C+NTFG+++C+C PG+ +D + C+ D+DEC + P G CYN G++ C C +Y+ + G +CM M+++
Sbjct: 990 SFKCNCENGFVLDAEGKNCTDIDECKISHDICGMGTCVNTPGSFDCECMEGFESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFKCLCPPGHDLNEDGTVCLDV-----------------------DECSLSGNLCRNGR-----CVNMIGSYQCSCNTGYSATPDRQGCVDIDECTI--MNGG-----------------------------CDTHCSNSDGSYECSCERGYALLPDTRSCSDIDECEDNPYLCDGGQCTNVPGEYRCLCYDGFISSVDMKTCSDVNECELNPNICIHGKCENTRGSFICHCKVGFTVKKGSTGCTDVDECEIGAHNCDMHATCANVQGSFKCTCIEGYFGDGVKCQDVDECANGTHNCIPEAKCVNIPGTFTCVCRDGFSGDGQTCVDMDECAENVNLCEFGQCLNSAGGYRCECEMGFVPTVDGRSCKDIDECMFDNICVFGKCENVPGMFRCVCDPGYEIDETGGNC-TDKDECADPSNCFNGICTNTQGSFLCTCPADYQMSP-SGQGCVGTDYRVGKCFLESTERGDGTLSCNVEIGIGISRSSCCCSLGRAWGAPCELCPVVNTTEYRILCPGGEGFRPNPYTVILEDIDECTELPGLCQG--GNCQNTFGSFKCVCQPGFRFNEDNRQCE-------------------------------------DIDECANF-PTVCGPGTCYNIVGNYTCVCPPDYMQVNGGNNCMDMRKS 1635 HSP 9 Score: 105.145 bits (261), Expect = 5.449e-23 Identity = 151/539 (28.01%), Postives = 218/539 (40.45%), Query Frame = 1
Query: 994 CLELRTCSKGCQNG-GTCFQG----RCQCTEGFEGDQCQL--EINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGN-----------CKCKQGWK----GKFCNDDVDECLFP-VCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDC----LNGICYCFS-----------------GWHGEDCSL------------------------DIDECKYNHG-CEH-LCVNVPGSFNCQCHSGFTLQINKKKCIS--------KSCNIECLNGGLCDKDKCKCPPGYI----GHNCEFNDFCHFISPCEHNCTTINDNMV----CSCLPGYDLMP----DKKTCKKLECPKCVRGTCNEN----KCKCPKGFA----GLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCD---EDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSH 2292
C++ CS G G GTC C C +GFE ++N CS + C CVN +++C C +G+ L D + C ++ + G S N C C G+ G+ C D+ + L P +C+ C+N +GSY+C C EGFTL + C+++ + G C + +C S GW G+ C + DIDEC G C H C+N GS++C C++G+T I + C+ K CN C N +C CP GYI G C D C + +HNC + N + C C PG+ D C +G C + C+C KGF+ G CE D++EC CQH C N +G + C C +G+ C+ N+ T + C C+N+ KC C +GY + D+NEC C C NTEG Y C C PG+ + H
Sbjct: 2110 CVDANECSIGNPCGNGTCLNVPGGFECTCDDGFEPGPMMTCEDLNECSLNPL---LCAFRCVNN-FGSYECMCPTGYVLREDRRMCKDQDECEEGLDNCASRNMICKNLIGTYMCICPPGYTRRPDGEGCIDENECRLKPGICENGRCINNVGSYKCVCNEGFTLNQD---ETECVDS--RRGFCFTEVIQSLCQMVSSSRNLVTKSECCCDGGRGW-GQQCDICPLPGTAQYKKLCPHGPGYTTDGRDIDECTVMPGMCHHGQCINSEGSYHCMCNNGYTTDITRTGCVDLDECAQSPKPCNFICKNTE--GSYQCACPRGYIMQEDGRTCRDLDEC---ASKQHNCQFLCVNTIGGFTCKCPPGFTQHHTACIDNNECVSQPGTCGSKGVCQNSPGSFSCECQKGFSLDNSGSNCE-DMDECSGNHRCQHGCQNMLGGYRCGCPSGYLQHFQWNQCVDENECT-NPQVCGSASCYNTLGSFKCACPNGYNFDQFSGGCNDVNECSHSKAPCNFGCSNTEGGYLCGCPPGYFRAGQGH 2631
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008854.1 (pep scaffold:Pmarinus_7.0:GL476328:1008604:1022137:1 gene:ENSPMAG00000008009.1 transcript:ENSPMAT00000008854.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 146.747 bits (369), Expect = 1.601e-36 Identity = 187/643 (29.08%), Postives = 246/643 (38.26%), Query Frame = 1
Query: 1282 CKCKQGWKGKFCN---DDVDECLFPV-CQQI--CVNTIGSYQCSCREGFT------------LLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHG-CEHLCVNVPGSFNCQCHSGFTLQINKKKC--ISKSCNIECLNGGLCDKDK----CKCPPGY---IGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYD----LMPDKKTCKKLECPKCVRGTC----NENKCKCPKGFAGL---------------------LCEN---------------------DINECL-NQTICQHVCTNTIGSFFCRCKNGHKLA----EDKRSCIPPNKKTCLDKDCVHGQCFNSK--CICKSGYRGKRCD-EDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELC-----DV-----DIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSP----CKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISK--------------------HGCIG---------------------ECRNTFGNYECICPPGYLVLDDQKTCQISTKDTM 2769
C+CK G+ +DV+ECL P CQ CVNT GS+ C+C GFT L +NG C+ C+N C + Y + C DI+EC N G C C N GSF C C SG+T+ K C I++ N C + G C C C GY CE + C S C N CT + + C C PGY + D C P C GTC +C CP G+ +C+N DINECL N C NT G F C C ++L E C P +K C + S C CK+GY G D++EC K C+NT GSY C C G+I N+ + + CS C N+KC G C DV D+DECL + CQH C N+ GSY C C + + ++G C++ D C +P C C N+ KC CKP + GD DI C +PI+ G +G C + G ++CICPPGY+ ++ T TM
Sbjct: 31 CQCKPGFAKNPTTGECEDVNECLLPQQCQTSAHCVNTFGSFTCACNAGFTGNGYNCQDINECLTNNGNCSDICVNE-QGGYHCACPVGYTLDPINHAAC-FDINECMVNKGNCSQNCQNTEGSFACTCWSGYTMNTTTKTCVDINECLNNPCGSSGSCSNIDGSYICNCLRGYQLNSARICENINEC-LTSACGPNAICTDLIGSFTCQCQPGYSSNGTMCLDINECANTASPMCPIGTCENLPGSYRCHCPSGYTAANNTCRDVNECLIIPSPCGSNSICQNTPGFYTCLCSSGFTSVSGVCQDINECLANPCAAPASCINTAGGFQCNCPLDYQLNGNICEAVNQCTVPGQKLCSENAVCISTLGTSAYTCQCKAGYTGNGTVCTDVDECVKKPCPVNTVCLNTFGSYTCQCAAGYIYLNNTCTDLNECSSVNLFSCPPNSKCVNAIGSYSCQCVPGYQDVKGACQDVDECLRDNGGCQHLCFNNVGSYRCGCRPGYLSAGLNGYMCIDI-DECQNPTLNNCNQNAVCTNTRGSFKCACKPYFKGDGITCDIGRCGYPINSCDPNAICDISNPQSPRCVCPSGWVGTGKKCYDVNECLNPCTCPASTTCMDLDGGFKCICPPGYIFSNNVCVDSYPTVRTM 669 HSP 2 Score: 98.5969 bits (244), Expect = 2.392e-21 Identity = 175/683 (25.62%), Postives = 273/683 (39.97%), Query Frame = 1
Query: 955 FSCICGIKETQN--NCLELRTCSKGCQNGGTCF------QG--RCQCTEGFEGDQCQ----LEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCI------KEECSKFGTTEVVSGN--CKCKQGWK---GKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGI-----------CYCFSGWHGEDCS-LDIDECKYNH---GCEHLCVNVPGSFNCQCHSGFT----LQINKKKCISKSCNI--ECLN--GGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAG--LLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGH----KLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRG-KRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSA-NSHSC----------------QSVCS--------LCK------------------------NGKCDFNN----KCKCKTGW--TGELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLST---VDGRSCLEKNDS----------CSSPCKNGGKCVNS----KCKCKPGYNG 2604
F+C C T N NC ++ C N G C QG C C G+ D +IN C + C C N E +F C C SG+ ++ K+C+ C G+ + G+ C C +G++ + C ++++ECL C IC + IGS+ C C+ G++ SNG ++ +N C + I C+C SG+ + + D++EC G +C N PG + C C SGFT + + +C++ C C+N GG +C CP Y + N + C ++ C +PG L + C GT + C+C G+ G +C D++EC+ + VC NT GS+ C+C G+ D C N +C + C C GY+ K +D++EC + + C+H C N GSY+C C PG++ + N + C +VC+ CK N CD +N +C C +GW TG+ C D++ECL N C + C++ +G + C C + S VD + D+ S+PC++ GKC + C C GY G
Sbjct: 71 FTCACNAGFTGNGYNCQDINECLT---NNGNCSDICVNEQGGYHCACPVGYTLDPINHAACFDINEC---MVNKGNCSQNCQNT-EGSFACTCWSGYTMNTTTKTCVDINECLNNPCGSSGSCSNIDGSYICNCLRGYQLNSARIC-ENINECLTSACGPNAICTDLIGSFTCQCQPGYS--SNGTMCLD-INECANTASPMCPIGTCENLPGSYRCHCPSGYTAANNTCRDVNECLIIPSPCGSNSICQNTPGFYTCLCSSGFTSVSGVCQDINECLANPCAAPASCINTAGGF----QCNCPLDY-----QLNGNICEAVNQCT--------------VPGQKLCSENAVCIS------TLGT-SAYTCQCKAGYTGNGTVCT-DVDECVKKPCPVNTVCLNTFGSYTCQCAAGYIYLNNTCTDLNECSSVNLFSCPPNSKCVNAIGSYSCQCVPGYQDVKGACQDVDECLRDNGGCQHLCFNNVGSYRCGCRPGYLSAGLNGYMCIDIDECQNPTLNNCNQNAVCTNTRGSFKCACKPYFKGDGITCDIGRCGYPINSCDPNAICDISNPQSPRCVCPSGWVGTGKKC-YDVNECL-NPCTCPASTTCMDLDGGFKCICPPGYIFSNNVCVDSYPTVRTMDTSRFSSFGNNCASNPCQHNGKCTENDNGFSCSCVTGYTG 709 HSP 3 Score: 96.2857 bits (238), Expect = 1.265e-20 Identity = 140/468 (29.91%), Postives = 183/468 (39.10%), Query Frame = 1
Query: 1819 CLPGYDLMPDKKTCKKLECPKCVRGTCNENK--CKCPKGFA----GLLCENDINECLNQTICQHV--CTNTIGSFFCRCKNGHKLA----EDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDE----DINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNS----KCKCKPGY--NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLD----DQKTCQISTKDTMCNPHCLN----------------GGVCRDMSRCY--------------------CPIGFH--GIDCGVDVDECQRYAPCDKL---RGICYNTYG--SFYCQCSSNYVLMYDGTSCMTMKEAVLKP 3015
CL D P TC + V T N + C+C GFA CE D+NECL CQ C NT GSF C C G +D C+ N C D CV+ Q C C GY + DINEC C C NTEGS+ C+C G+ ++ + +C VDI+ECL N +C N +GSY C+C + L++ R C N+ +S C C + C+C+PGY NG C DINEC S IG C N G+Y C CP GY + D C I N C N GVC+D++ C CP+ + G C V++C P KL +C +T G ++ CQC + Y +GT C + E V KP
Sbjct: 3 CLEKTDCNPLTSTCVDI-----VYNTLNNSGFYCQCKPGFAKNPTTGECE-DVNECLLPQQCQTSAHCVNTFGSFTCACNAGFTGNGYNCQDINECLT-NNGNCSDI-CVNEQ-GGYHCACPVGYTLDPINHAACFDINECMVNKGNCSQNCQNTEGSFACTCWSGYTMNTTTKTC------------------------------VDINECLNNPCGSSGSCSNIDGSYICNCLRGYQLNSA--RICENINECLTSACGPNAICTDLIGSFTCQCQPGYSSNGTMCL-DINECANTASPMCPIGTCENLPGSYRCHCPSGYTAANNTCRDVNECLIIPSPCGSNSICQNTPGFYTCLCSSGFTSVSGVCQDINECLANPCAAPASCINTAGGFQCNCPLDYQLNGNICEA-VNQCT--VPGQKLCSENAVCISTLGTSAYTCQCKAGYT--GNGTVCTDVDECVKKP 423
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006555.1 (pep scaffold:Pmarinus_7.0:GL476370:200676:210822:-1 gene:ENSPMAG00000005922.1 transcript:ENSPMAT00000006555.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 133.65 bits (335), Expect = 5.188e-32 Identity = 240/863 (27.81%), Postives = 340/863 (39.40%), Query Frame = 1
Query: 802 CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKR----KLDFSCIC--GIKETQNNCLELRTC----SKGCQNGGTCFQG----RCQCTEGFEG--------DQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIK-EECSKFGTTE----------VVSGNCKCKQGW--KGKFCNDDVDECLFPV----CQQICVNTIGSYQCSCREGFTLL------SNGKCAINCLNNCNKNGD--------CLNGI----CYCFSGWHGEDCS-LDIDECKY---NHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCE--FNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAG--LLCENDINECL---NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIP-----------------------PNKKTCLDKDCVHGQCFNSKC-----------ICKSGYRGKRCDEDINECKKYSHIC---EHFCMNTEGSYKCSCMPGFILSAN-----------SHSCQSVCSLCKNGKCDFNNKCKCKTGW--TGELCDVDIDECLLNQHKC---QHNCVNSNGSYSCSCNLPFYLST----VDGRSCLEKNDSCS--SPCKNGGKCVNSKCKCKPGY--NGDSCEEDINECQ-WPISKHGCIGECRNTFGNYECICPPGYL----VLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHG-IDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
CG+ CV + C C G+ G V L+ + C L + CS + F C C G ++T C+++ C S C G C C C G+ G D+C L N+CS N TC++ +FQC+C +GFQ G+ C+ EC G+ V S NC C G+ G C DVDECL P C NT GS+QC C GF + + KC +N C+ +G C+N + C C +G+ G LD+DEC N C N PGSF CQC +GF Q + + CN+ K + NC+ + +S C ++ N+ + D C+ C G T C C G+ G +C D++ECL N C NT GSF C+C G ++ I PN L K+ N C G++C D+NEC+ +C+NT GSY C C+ G+I + S++C S S CKN F +C+C G+ TGE C VD++EC + CVN+ GSY+C C L Y+ +D CL +++CS S CKN + +C+C G+ G+ C D+NECQ + + G C NT G+Y C+C GY+ V D C + + + N C N +C C GF D++EC R L +C NT GS+ C C+ Y
Sbjct: 170 CGQGAYCVNTVGSYNCPCLAGYIGNGTVCLDVDEC-----LLPSNNCSANSTCKNTPGSFQCQCDAGFQKTGEKCVDVNECQTSGSAACGPGAYCVNTVGSYNCPCLAGYIGNGTVCLDVDECLLPSNNCSA----NSTCKNT-----PGSFQCQCDAGFQ--KTGEKCVDVNECQTSGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVC-LDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQNVFPPPSETGEKCVD--VNECHTSGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGF--QSDFHGFGMRQCNLG-------SSYKLSIHKISLVMNCQSILGMMLYKLSKCCVLGSSAYSNVFPPPSETGEKCVDVNECQTFGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVCL-DVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQIQSSIHKSILGMMVSVVYIYIEFILQLFLARDYPNYSYELGKNKNTAHQKNPTCPLLIFHFYGLKFIWISETGEKC-VDVNECQTSGSAACGPGAYCVNTVGSYNCPCLAGYIGNGTLCLDVDECLLPSNNC-SANSTCKNTPGSF--QCQCDAGFQKTGEKC-VDVNECHTSGSAACGPGAYCVNTVGSYNCPC-LAGYIGNGTLCLDVDECLLPSNNCSANSTCKNTPG--SFQCQCDAGFQKTGEKCV-DVNECQTFGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNT---PGSFQCQCDAGFQSNATVCEDINECGRVPAVCGLGTVCENTVGSYRCPCAPGY 991 HSP 2 Score: 123.635 bits (309), Expect = 5.980e-29 Identity = 248/883 (28.09%), Postives = 340/883 (38.51%), Query Frame = 1
Query: 985 QNNCLELRTCSKG----CQNGGTCFQG----RCQCTEGFEG--------DQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIK-EECSKFGTTE----------VVSGNCKCKQGW--KGKFCNDDVDECLFPV----CQQICVNTIGSYQCSCREGFTLLSN-----GKCAINCLNNCNKNGDCLNGI----CYCFSGWHGEDCS-LDIDECKY---NHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCI-----SKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISP---CEHNCTTIND--NMVCSCLPGY-DLMP----------DKKTCKKLECPKCVRG-----TCNENKCKCPKGFAG--LLCENDINECL---NQTICQHVCTNTIGSFFCRCKNG------------------HKLAEDKRSCI-----------------------------PPNKKT---CLDKD---------CVHGQ-CFNS----KCICKSGYRGKRCD-EDINECKKYSHICE--HFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLC------------------------------KNGKCDFNNKCK--------CKTGW---TGELCDVDIDECLLNQHKC---QHNCVNSNGSYSCSCNLPFYLST----VDGRSCLEKNDSCS--SPCKNGGKCVNSKCKCKPGY--NGDSCEEDINECQWPISKH-GCIGECRNTFGNYECICPPGYL----VLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFH--GIDCGVDVDECQRYAPCDKLRGI-CYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVL 3009
Q C+++ C K C +G C C+C G+ G D+C L N+CS N TC + ++QC+C +GFQ G+ C +EC KFG+ V S NC C G+ G C DVDECL P C NT GS+QC C GF +C + C C+N + C C +G+ G LD+DEC N C N PGSF CQC +GF Q +KC+ S + C G C C C GYIG+ D + P C N T N + C C G+ ++ P D C C G T C C G+ G +C D++ECL N C NT GSF C+C G +KL+ K S + PP +T C+D + C G C N+ C+C +GY G D++EC S+ C C NT GS++C C GF + ++ H +S+ + KN N C K W TGE C VD++EC + CVN+ GSY+C C L Y+ +D CL +++CS S CKN + +C+C G+ G+ C D+NEC S G C NT G+Y C C GY+ + D C + + + N C N +C C GF G C VDV+ECQ + G C NT GS+ C C + Y+ +GT C+ + E +L
Sbjct: 70 QRTCIDVDECEKAGSALCGHGAYCANTLGSYACRCLVGYVGNGTVCLDVDECLLPSNNCSA----NSTCTNT-----PGSYQCQCDAGFQ--KTGEMCTDVDECLKFGSAACGQGAYCVNTVGSYNCPCLAGYIGNGTVC-LDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQKTGEKCVDVNECQTSGSAACGPGAYCVNTVGSYNCPCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGF--QKTGEKCVDVNECQTSGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQNVFPPPSETGEKCVDVNECHTSGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVCL-DVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQSDFHGFGMRQCNLGSSYKLSIHKISLVMNCQSILGMMLYKLSKCCVLGSSAYSNVFPPPSETGEKCVDVNECQTFGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQIQSSIH--KSILGMMVSVVYIYIEFILQLFLARDYPNYSYELGKNKNTAHQKNPTCPLLIFHFYGLKFIWISETGEKC-VDVNECQTSGSAACGPGAYCVNTVGSYNCPC-LAGYIGNGTLCLDVDECLLPSNNCSANSTCKNTPG--SFQCQCDAGFQKTGEKC-VDVNECHTSGSAACGPGAYCVNTVGSYNCPCLAGYIGNGTLCLDVDECLLPSNNCSANSTCKNT---PGSFQCQCDAGFQKTGEKC-VDVNECQTFGSAACGPGAYCVNTVGSYNCLCLAGYI--GNGTVCLDVDECLL 924 HSP 3 Score: 114.775 bits (286), Expect = 4.229e-26 Identity = 178/640 (27.81%), Postives = 265/640 (41.41%), Query Frame = 1
Query: 1360 ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQ--INKKKCI-----SKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISP---CEHN--CTTINDNMVCSCLPGY----DLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAG--LLCENDINECL---NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNK-KTCLDKDCVHGQ-CFNS----KCICKSGYRGKRCD-EDINECKKYSHICE--HFCMNTEGSYKCSCMPGFILSA----NSHSCQSVCSL-------CKNGKCDFNNKCKCKTGWTG--ELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFY----LSTVDGRSCLEKND---SCSSPCKNGGKCVNS----KCKCKPGY--NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLV-----------LDDQKTCQISTKDTMCNPHCLNGGVCRDMSRC-----------YCPIGFHGIDCGVDVDECQRYAPCDKLRGI-CYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVL 3009
C +TIGS++C C G+ +S+ + C +C +GI YN C N+ G++ C C+SG+ L ++ CI K+ + C +G C C+C GY+G+ D + P C N CT + C C G+ ++ D C K C +G T C C G+ G +C D++ECL N C NT GSF C+C G + +K C+ N+ +T C G C N+ C C +GY G D++EC S+ C C NT GS++C C GF + + + CQ+ S C N +N C C G+ G +C +D+DECLL + C N C N+ GS+ C C+ F + G C++ N+ S S+ C G CVN+ C C GY NG C D++EC P + C+NT G+++C C G+ L I + N + G + +S+C + P G C VDV+ECQ + G C NT GS+ C C + Y+ +GT C+ + E +L
Sbjct: 3 TCTDTIGSFKCGCVAGYAAVSDSR-------TCQDVDECQSGI--------------------YNCTQYSTCHNLDGNYTCICNSGYYLNEFPMQRTCIDVDECEKAGSALCGHGAYCANTLGSYACRCLVGYVGNGTVCLDVDECLLPSNNCSANSTCTNTPGSYQCQCDAGFQKTGEMCTDVDECLKFGSAACGQGAYCVNTVGSYNCPCLAGYIGNGTVCL-DVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQKTGEK--CVDVNECQTSGSAACGPGAYCVNTVGSYNCPCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQKTGEKCVDVNECQTSGSAACGPGAYCVNTVGSYN--CLCLAGYIGNGTVC-LDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQNVFPPPSETGEKCVDVNECHTSGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVCL-DVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQSDFHGFGMRQCNLGSSYKLSIHKISLVMNCQSILGMMLYKLSKCCVLGSSAYSNVFPPPSETGEKC-VDVNECQTFGSAACGPGAYCVNTVGSYNCLCLAGYI--GNGTVCLDVDECLL 605 HSP 4 Score: 110.538 bits (275), Expect = 7.910e-25 Identity = 214/803 (26.65%), Postives = 309/803 (38.48%), Query Frame = 1
Query: 1054 RCQCTEGFEG----------DQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN--DGKSCIK-EECSKFGTT----------EVVSGNCKCKQGW--KGKFCNDDVDECLFPV----CQQICVNTIGSYQCSCREGFTLLSNGKCAIN-CLN----NCNKNGDCLNGI----CYCFSGWHGEDCS-LDIDECKY---NHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCI-----SKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISP---CEHNCTTIND--NMVCSCLPGYDLMPDK----KTCKKLECPKCVRG-----TCNENKCKCPKGFA--GLLCENDINECL---NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHIC---EHFCMNTEGSYKCSCMPGFILSAN-----------SHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQ-----------------------HKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKND---SCSSPCKNGGKCVNS----KCKCKPGY--NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCN------PHCLNGGVCRDMSRCYCPIG-------------------FHGI------DCG---VDVDECQRYAPCDKLRGI-CYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVL 3009
+C C G+ D+CQ I +C++ TC ++ + N+ C C SG+ L+ ++CI +EC K G+ + S C+C G+ G C DVDECL P C NT GSYQC C GF ++ CL C + C+N + C C +G+ G LD+DEC N C N PGSF CQC +GF Q +KC+ S + C G C C C GYIG+ D + P C N T N + C C G+ +K C+ C G T C C G+ G +C D++ECL N C NT GSF C+C G ++ PP +T G++C D+NEC +C+NT GSY C C+ G+I + S++C S S CKN F +C+C G+ + + +C L +K CV + +YS N+ F + G C++ N+ S+ C G CVN+ C C GY NG C D++EC P + C+NT G+++C C G+ + Q + S M + L + RD +G F+G+ + G VDV+ECQ G C NT GS+ C C + Y+ +GT C+ + E +L
Sbjct: 12 KCGCVAGYAAVSDSRTCQDVDECQSGIYNCTQ----YSTCHNL-----DGNYTCICNSGYYLNEFPMQRTCIDVDECEKAGSALCGHGAYCANTLGSYACRCLVGYVGNGTVC-LDVDECLLPSNNCSANSTCTNTPGSYQCQCDAGFQKTGEMCTDVDECLKFGSAACGQGAYCVNTVGSYNCPCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGF--QKTGEKCVDVNECQTSGSAACGPGAYCVNTVGSYNCPCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQKTGEKCVDVNECQTSGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVCL-DVDECLLPSNNCSANSTCKNTPGSFQCQCDAGF------QNVFPPPSET-----------------------GEKC-VDVNECHTSGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVCLDVDECLLPSNNC-SANSTCKNTPGSF--QCQCDAGFQSDFHGFGMRQCNLGSSYKLSIHKISLVMNCQSILGMMLYKLSKCCVLGSSAYS---NV-FPPPSETGEKCVDVNECQTFGSAACGPGAYCVNTVGSYNCLCLAGYIGNGTVC-LDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGFQI---QSSIHKSILGMMVSVVYIYIEFILQLFLARDYPNYSYELGKNKNTAHQKNPTCPLLIFHFYGLKFIWISETGEKCVDVNECQTSGSAACGPGAYCVNTVGSYNCPCLAGYI--GNGTLCLDVDECLL 758
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Match: JAG1 (jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188]) HSP 1 Score: 127.487 bits (319), Expect = 4.208e-30 Identity = 170/654 (25.99%), Postives = 277/654 (42.35%), Query Frame = 1
Query: 1021 GCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-----QLDNDGKSCIKEECSKFGTTEVVSG--NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFT----LLSNGKCAINCLNNCNKNGDCLNGI-CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKN-------GKC-DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQIS--TKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDV 2865
GC +GG C+C + G C ++N C Q C N ++++C CQ G+ ++D + C+ G++ C C GW G C +D+DEC C C+N + ++C+C +T L+ +C N + + G C C GW G++C +D+++C+ C ++ ++C+C G+T + + + +++ + CLNGG C D C C G+ G +CE + D C +PC++ +N LP D C C + F G C + CL + CQ + + T+ ++G +A + PN + C+ N C+C SG+RG C E++N+C + + C++ S++C C G+ + C++ C N G C D N C+CK GW G+ C I C C + ++ CSC + +G +C + ++ +C +PC+NG CV S KC C+ G+ G +C +DIN+C S H C G C + Y C C G+ +D CQ KD C +NG RC CP+G G C +V
Sbjct: 133 GCVHGGCSKPWECRCDTNWGGLLCDKDLNYCGNHQPCRNGGS--CSNAQPDSYKCDCQKGYHGVNCEIDYVQHITLNNTCANGGSSVGSPSGYKCLCAPGWTGANCTEDIDECASSPCGNGGTCLNLVNGFRCTCPPQWTGHTCLVDTDECDDNPCVHARSCKNLFGGYYCGCLPGWTGQNCDIDVNDCEGKCLNGGTCKDLVNDYSCECKPGYTGRRCETE-VNECASHPCLNGGQCRDAIDSYYCVCMDGFAGDSCELDVDLC-VPNPCQNGARCVN-------LPNGDYF-----------------------CHCSENFEGTNCTLLKDHCLT-SPCQVIDSCTVAVPSNTSESG--VAHVTSTVCGPNGR------CLSQAGGNFTCMCNSGFRGSFCHENVNDCAEGACHNGGTCLDGINSFQCMCPDGW----DGEFCENDVDDCSNHNPCLNGGTCHDLVNDFSCECKNGWKGKTCHSKISHCDEATCNNGGECFDVGDTFRCSCPTGW-----EGPTCNIAQSIACMPNPCQNGATCVISGDSYKCICQSGWEGANCTQDINDC----SSHPCYNGGTCVDGTNWYRCECAAGF-AGEDINECQSMPCAKDATCIDE-ING------YRCMCPLGRAGRHCHDEV 722 HSP 2 Score: 120.553 bits (301), Expect = 5.882e-28 Identity = 180/684 (26.32%), Postives = 272/684 (39.77%), Query Frame = 1
Query: 1063 CTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLD-----NDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVN-------TIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGI----------CYCFSGWHGEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQC---HSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGHKLAE---DKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL----SANSHSCQSVCSLCKNGKC----DFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS--PCKNGGKC---VNS-KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDT-MCNPHCLNGGVC---RDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C +G+ G C+ I + G T C N GE N C+CQ G+Q C+ CSK C+C W G C+ D++ C Q C N SY+C C++G+ ++ C I+ + + N C NG C C GW G +C+ DIDEC + G C+N+ F C C +G T ++ +C C L C C PG+ G NC+ + ++ CE C + TCK L N+ C+C G+ G CE ++NEC + + C + I S++C C +G D C+P N C++ +G F C C + G C + + C+ + SC S +H +VC NG+C N C C +G+ G C ++++C C++ S+ C C + DG C D CS+ PC NGG C VN C+CK G+ G +C I+ C +G GEC + + C CP G+ + TC I+ M NP C NG C D +C C G+ G +C D+++C + PC G C + + C+C++ +
Sbjct: 81 CLDGWTGGDCKKAI-----CRQGCSTEHGQCDNPGECN--CRCQYGWQGHFCDQCIPYPGCVHGGCSK-------PWECRCDTNWGGLLCDKDLNYCGN---HQPCRNGGSCSNAQPDSYKCDCQKGYHGVN---CEIDYVQHITLNNTCANGGSSVGSPSGYKCLCAPGWTGANCTEDIDECASSPCGNGGTCLNLVNGFRCTCPPQWTGHTCLVDTDECDDNPCVHARSCKNLFGGYYCGCLPGWTGQNCDID-----VNDCEGKCL------------------NGGTCKDL---------VNDYSCECKPGYTGRRCETEVNECASHPCLNGGQCRDAIDSYYCVCMDGFAGDSCELDVDLCVPNPCQNGARCVNLP--NGDYF---CHCSENFEGTNCT-----------LLKDHCLTSPCQVIDSCTVAVPSNTSESGVAHVTSTVCG--PNGRCLSQAGGNFTCMCNSGFRGSFCHENVNDCAEGACHNGGTCLDGINSFQCMCPDGW-----DGEFCENDVDDCSNHNPCLNGGTCHDLVNDFSCECKNGWKGKTCHSKISHCDEATCNNG--GECFDVGDTFRCSCPTGW----EGPTCNIAQSIACMPNP-CQNGATCVISGDSYKCICQSGWEGANCTQDINDCSSH-PCYN-GGTCVDGTNWYRCECAAGFA 680
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000017.1 (pep scaffold:Pmarinus_7.0:GL477746:39241:65692:1 gene:ENSPMAG00000000015.1 transcript:ENSPMAT00000000017.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 122.479 bits (306), Expect = 1.457e-28 Identity = 204/716 (28.49%), Postives = 279/716 (38.97%), Query Frame = 1
Query: 1258 TTEVVSGNCKCKQGWKGKFCN-DDVDECLFP----VCQQICVNTIGSYQCSCREGFTLLSNGKCAIN-CLNN---CNKNGDCLNGI----CYCFSGW--HGEDCSLDIDECKYNHGCEH---LCVNVPGSFNCQCHSGFTLQINKKKCI-SKSCNIECLNG-----GLCD----KDKCKCPPGYI--GHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKL-------------------------------ECP---KCVRG--TCNEN--------KCKCPKGFAGL--LCENDINECLNQTICQHV-----CTNTIGSFFCRCKNGHKLAEDKRSCIPPNK-----KTCLDKDCVHGQCFNSKCICKSGYR-----------------------------GKRCDEDINECKKY-SHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCS-LCKNGKCDFNN---------KCKCKTGW--TGELCDVDIDECL-LNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEE----------DINECQWPISKH-GCIGECRNTFGNYECICPPGYL----VLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHG-IDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
T + S C CK G++G N D+DEC+ C+NT GSY C+C GFT IN C N C +C+NGI C C G+ +G C+ D+DECK + C+ +C N GS+ C C +G+ + C + C + LN GLC C+C GY G C H + + I N+ + D P K KK+ CP +C+RG C +N C C F+ + C+ + + +V T+TIGSF C C G+ + D R+C ++ C N CIC SGY G+ C D++EC+K S +C H +C NT GSY C C+ G++ N C V L + C N+ +C+C G+ TGE+C D+DECL C CVN GSY+C C L Y+ +G CL+ D C P N NS CK PG C+ D+NECQ S G C NT G+Y C C GY+ V D C + + + N C N +C C GF D+DEC R L +C NT GS+ C C+ Y
Sbjct: 108 TNTIGSYTCACKLGYEGNGWNCKDIDECMTGNHCNSNGSECMNTDGSYYCTCALGFTGNGTYCADINECTANPYLCQDTEECMNGIGSYKCECLPGYIRNGTICT-DVDECKKSQPCDANTMVCSNTIGSYTCLCKAGYQFDSTARICTDTDECVVSSLNNCSRTTGLCQNFDGSFTCQCKAGYTGDGVTCTGKLCFHVVGVPQCRGAVILCNLAVGVVLLCDFTPIKLYKKKVFDVDECNPPENATQPCKGPVGDLYGRDDAHCVCPDVDECIRGLHNCTQNCTNIEGGFTCSCFARFSSVNGTCKRKFHLSTSFVHVAYVYTLWPSTDTIGSFKCGCVAGYAVVSDSRTCQDVDECQSGIYNCTQYSTCRNLEGNYTCICNSGYESAHSIPTQGVYSFEFKHSNLSPPPQPPESGETC-IDVDECQKAGSALCGHGAYCANTLGSYACRCLVGYV--GNGTVCLDVDECLLPSNNCSANSTCTNTPGFYQCQCDAGFQKTGEMC-TDVDECLKFGSAVCGQGAYCVNMVGSYNCPC-LAGYIG--NGTVCLDV-DECQLPSNNCS--ANSTCKNTPGSFQCQCDAGFQKTAEICVDVNECQTSGSAACGPGAYCVNTVGSYNCQCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNT---PGSFQCQCDAGFQSNATVCEDIDECGRVPTVCGLGTVCENTVGSYRCPCAPGY 809 HSP 2 Score: 108.997 bits (271), Expect = 2.230e-24 Identity = 183/658 (27.81%), Postives = 259/658 (39.36%), Query Frame = 1
Query: 1084 DQCQLEINSCS-----RGQMGNRTC--------EHICVNEGENNFQCK---CQSGFQLDNDGKSCIK-EECSKFGTT----------EVVSGNCKCKQGW--KGKFCNDDVDECLFPV----CQQICVNTIGSYQCSCREGFTLLSNGKCAIN-CLN----NCNKNGDCLNGI----CYCFSGWHGEDCS-LDIDECKY---NHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCI-----SKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFA--GLLCENDINECLN-QTICQ--HVCTNTIGSFFCRCKNG------HKLAEDK-----------RSCIPPNKKTCLDKDC---VHGQCFN--SKC-ICKSGYR----------------GKRCDEDINECKKY-SHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKND--------SCSSPCKNGGKCVNSKCKCKPGYNGDSCE-EDINECQWPISKHGCIGECRNTFGNYECICPPGY 2718
D+CQ I +C+ R GN TC H +G +F+ K Q G++CI +EC K G+ + S C+C G+ G C DVDECL P C NT G YQC C GF ++ CL C + C+N + C C +G+ G LD+DEC+ N C N PGSF CQC +GF Q + C+ S + C G C C+C GYIG+ D + P +NC+ N C PG +C+C GF +CE DI+EC T+C VC NT+GS+ C C G H + E R+ + + +C +H +N +C +C + G+ C D++EC K+ S C +C+NT GSY C C+ G+I G +C +D+DECLL + C N C N+ GSY C C+ F +G CL+ ++ S +S CKN + +C+C G+ ++ EDI+EC + G C NT G+Y C C PGY
Sbjct: 462 DECQSGIYNCTQYSTCRNLEGNYTCICNSGYESAHSIPTQGVYSFEFKHSNLSPPPQPPESGETCIDVDECQKAGSALCGHGAYCANTLGSYACRCLVGYVGNGTVC-LDVDECLLPSNNCSANSTCTNTPGFYQCQCDAGFQKTGEMCTDVDECLKFGSAVCGQGAYCVNMVGSYNCPCLAGYIGNGTVCLDVDECQLPSNNCSANSTCKNTPGSFQCQCDAGF--QKTAEICVDVNECQTSGSAACGPGAYCVNTVGSYNCQCLAGYIGNGTVCLDVDECLLP-SNNCSA---NSTCKNTPG------------------------SFQCQCDAGFQSNATVCE-DIDECGRVPTVCGLGTVCENTVGSYRCPCAPGYQRNTNHTILETSFLYTFTNVPYHRASVIFGRPMTEAFECCTLIHYVEYNKVERCNVCSNTAENAFSYSNLPPSHPPETGEMC-TDVDECLKFGSAACGQGAYCVNTVGSYNCPCLAGYI-------------------------------GNGTVC-LDVDECLLPSNNCSANSTCTNTPGSYQCQCDAGFQRYIGNGTVCLDVDECLLPSNNCSANSTCKNMPG--SFQCQCDAGFQSNATVCEDIDECGRVPTVCGLGTVCENTVGSYRCPCAPGY 1052 HSP 3 Score: 105.145 bits (261), Expect = 3.433e-23 Identity = 200/752 (26.60%), Postives = 283/752 (37.63%), Query Frame = 1
Query: 1153 CVNEGENNFQCKCQSGFQ----LDNDGKSCIKE-ECS-----------KFGTTEVVSGNCKCKQGWKGKFCN-DDVDECLF-----PVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH---LCVNVPGSFNCQCHSGFT------LQINKKKCISKSC--NIECLNGGLCDKDKCKCPPGYI--GHNCEFNDFCHFISPCEHN---CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCN--------------ENKCKCPKGFAG--LLCEND-------INECLNQTICQHVCTNTIGSF----FCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCF---NSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-----------LSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWT----GELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCN----------------LPFYLSTV--------DGRSCLEKND---SCSSPCKNGGKCVNS----KCKCKPGY--NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMC----NPHCLNGGVCRDMSRCY---CPIGF--HGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV----LMYDGTSCMTMKEAVLKP 3015
CVN ++ C C +GF+ +D +C+ E ECS F + S +C C G+ G C D++EC+ PV C NTIGSY C+C+ G+ +GW+ +D IDEC + C C+N GS+ C C GFT IN+ C EC+NG KC+C PGYI G C D C PC+ N C+ + C C GY + C + +CV + N C+C G+ G + C + +C I +C +G F K K D C PP T K V G + ++ C+C D++EC + H C C N EG + CSC F LS + V +L + + KC C G+ C D+DEC + C C N G+Y+C CN F S + G +C++ ++ + S+ C +G C N+ C+C GY NG C D++EC P + C NT G Y+C C G+ QKT ++ T C + C G C +M Y C G+ +G C +DVDECQ + C NT GSF CQC + + + D C T A P
Sbjct: 17 CVNT-PGHYDCSCNAGFRGNGFIDCQESTCLHEDECSVKNNPCLSVNNSFCNNSIGSYSCICTSGYNGTTCEVTDINECISGQNNCPV-NANCTNTIGSYTCACKLGYE----------------------------GNGWNCKD----IDECMTGNHCNSNGSECMNTDGSYYCTCALGFTGNGTYCADINECTANPYLCQDTEECMNG--IGSYKCECLPGYIRNGTICTDVDECKKSQPCDANTMVCSNTIGSYTCLCKAGYQFDSTARICTDTD--ECVVSSLNNCSRTTGLCQNFDGSFTCQCKAGYTGDGVTCTGKLCFHVVGVPQCRGAVI---LCNLAVGVVLLCDFTPIKLYKKKVFDVDECNPPENATQPCKGPV-GDLYGRDDAHCVCP----------DVDECIRGLHNCTQNCTNIEGGFTCSCFARFSSVNGTCKRKFHLSTSFVHVAYVYTLWPSTDTIGSFKCGCVAGYAVVSDSRTCQ-DVDECQSGIYNCTQYSTCRNLEGNYTCICNSGYESAHSIPTQGVYSFEFKHSNLSPPPQPPESGETCIDVDECQKAGSALCGHGAYCANTLGSYACRCLVGYVGNGTVC-LDVDECLLPSNNCSANSTCTNTPGFYQCQCDAGF-----QKTGEMCTDVDECLKFGSAVCGQGAYCVNMVGSYNCPCLAGYIGNGTVC-LDVDECQLPSNNCSANSTCKNTPGSFQCQCDAGFQKTAEICVDVNECQTSGSAACGP 708 HSP 4 Score: 99.3673 bits (246), Expect = 2.430e-21 Identity = 178/691 (25.76%), Postives = 268/691 (38.78%), Query Frame = 1
Query: 1174 NFQCKCQSGFQLDNDGKSCIKEE--------CSKFGTTEVVSGN--CKCKQGWK-----------------------------GKFCNDDVDECL---FPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN---CL---NNCNKNGDCLNGI----CYCFSGWH--GEDCSLDIDEC-KYNH---GCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC-DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGF--AGLLCENDINECLNQTICQ----HVCTNTIGSFFCRCKNGH----KLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCD-EDINECKKYSHICE--HFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHN-------CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC----SSPCKNGGKCVNS----KCKCKPGY--NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGY-LVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHG-IDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
+F+C C +G+ + +D ++C + C+++ T + GN C C G++ G+ C DVDEC +C C NT+GSY C C G+ + NG ++ CL NNC+ N C N C C +G+ GE C+ D+DEC K+ G CVN+ GS+NC C +G+ NG +C D D+C+ P +NC N C + T +C+C GF +C D+NEC C NT+GS+ C+C G+ + D C+ P+ + C + + +C C +G++ EDI+EC + +C C NT GSY+C C PG+ + N H+ L F N + + EC H ++N C N+ + NLP G C + D C S+ C G CVN+ C C GY NG C D++EC P + C NT G+Y+C C G+ + + C + + + +C C++M +C C GF D+DEC R L +C NT GS+ C C+ Y
Sbjct: 440 SFKCGCVAGYAVVSDSRTCQDVDECQSGIYNCTQYSTCRNLEGNYTCICNSGYESAHSIPTQGVYSFEFKHSNLSPPPQPPESGETC-IDVDECQKAGSALCGHGAYCANTLGSYACRCLVGY--VGNGTVCLDVDECLLPSNNCSANSTCTNTPGFYQCQCDAGFQKTGEMCT-DVDECLKFGSAVCGQGAYCVNMVGSYNCPCLAGYIG-----------------NGTVCLDVDECQLP----SNNCSANSTC-------------------------------------------KNTPGSFQCQCDAGFQKTAEICV-DVNECQTSGSAACGPGAYCVNTVGSYNCQCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNTP-GSFQCQCDAGFQSNATVCEDIDECGRVPTVCGLGTVCENTVGSYRCPCAPGYQRNTN-HTILETSFLYT-----FTNVPYHRASVIFGRPMTEAFECCTLIHYVEYNKVERCNVCSNTAENAFSYSNLPPSHPPETGEMCTDV-DECLKFGSAACGQGAYCVNTVGSYNCPCLAGYIGNGTVCL-DVDECLLPSNNCSANSTCTNTPGSYQCQCDAGFQRYIGNGTVCLDVDECLLPSNNCSANSTCKNMPGSFQCQCDAGFQSNATVCEDIDECGRVPTVCGLGTVCENTVGSYRCPCAPGY 1052 HSP 5 Score: 98.5969 bits (244), Expect = 3.852e-21 Identity = 153/564 (27.13%), Postives = 215/564 (38.12%), Query Frame = 1
Query: 931 SFDKRKLDFSCICGIKETQNNCLELRTCSKG----CQNGGTCFQG----RCQCTEGFEG--------DQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIK-EECSKFGTT----------EVVSGNCKCKQGW--KGKFCNDDVDECLFPV----CQQICVNTIGSYQCSCREGFTLLSN-----GKCAINCLNNCNKNGDCLNGI----CYCFSGWHGEDCS-LDIDECKY---NHGCEHLCVNVPGSFNCQCHSGFTLQINKKKC--------ISKSCNIECLNGGLCDKDKCKCPPGY---IGHNCEFNDF--------------------------CHFISPCEHN-------CTTINDNMVC-SCLPGY------DLMPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFA--GLLCENDINECL---NQTICQHVCTNTIGSFFCRCKNGHK-------LAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCD-EDINECKKYSHIC--EHFCMNTEGSYKCSCMPGF 2271
SF+ + + S E+ C+++ C K C +G C C+C G+ G D+C L N+CS N TC + +QC+C +GFQ G+ C +EC KFG+ V S NC C G+ G C DVDEC P C NT GS+QC C GF + +C + C C+N + C C +G+ G LD+DEC N C N PGSF CQC +GF Q N C + C + + +C C PGY H F C I E+N C+ +N S LP ++ D C K C +G T C C G+ G +C D++ECL N CTNT GS+ C+C G + + D C+ P+ + C + + +C C +G++ EDI+EC + +C C NT GSY+C C PG+
Sbjct: 505 SFEFKHSNLSPPPQPPESGETCIDVDECQKAGSALCGHGAYCANTLGSYACRCLVGYVGNGTVCLDVDECLLPSNNCS----ANSTCTNT-----PGFYQCQCDAGFQ--KTGEMCTDVDECLKFGSAVCGQGAYCVNMVGSYNCPCLAGYIGNGTVC-LDVDECQLPSNNCSANSTCKNTPGSFQCQCDAGFQKTAEICVDVNECQTSGSAACGPGAYCVNTVGSYNCQCLAGYIGNGTVCLDVDECLLPSNNCSANSTCKNTPGSFQCQCDAGF--QSNATVCEDIDECGRVPTVCGLGTVCENTVGSYRCPCAPGYQRNTNHTILETSFLYTFTNVPYHRASVIFGRPMTEAFECCTLIHYVEYNKVERCNVCSNTAENAFSYSNLPPSHPPETGEMCTDVDECLKFGSAACGQGAYCVNTVGSYNCPCLAGYIGNGTVCL-DVDECLLPSNNCSANSTCTNTPGSYQCQCDAGFQRYIGNGTVCLDVDECLLPSNNCSANSTCKNMP-GSFQCQCDAGFQSNATVCEDIDECGRVPTVCGLGTVCENTVGSYRCPCAPGY 1052 HSP 6 Score: 93.9745 bits (232), Expect = 1.157e-19 Identity = 163/608 (26.81%), Postives = 233/608 (38.32%), Query Frame = 1
Query: 1534 IDECKYNHGC---EHLCVNVPGSFNCQCHSGF----------TLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFIS-----PCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGT-CNENK-----------CKCPKGFA--GLLCENDINEC-LNQTICQHV--CTNTIGSFFCRCKNGH----KLAEDKRSCIPPNKKTCLDKDCVHGQCFNS-KCICKSGYR----GKRCDE-------DINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANS------------HSCQSVCSLCKNGK-----CDF--------------------NNKCKCKTGWTGELCD--------VDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS--------SPCKNGGKCVNSKCKCKPGY----NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGY---LVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGI-CYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVL 3009
IDEC N CVN PG ++C C++GF + +++ +C K+ +N C+ C C GY G CE D IS P NCT + C+C GY+ + CK ++ +C+ G CN N C C GF G C DINEC N +CQ C N IGS+ C C G+ + D C + C V S C+CK+GY+ + C + +N C + + +C++F +GS+ C C G+ + C+ LC CDF N CK G G+L D+DEC+ H C NC N G ++CSC F S+V+G + + S S + + + KC C GY + +C +D++ECQ I CRN GNY CIC GY + Q K + +P P + +DVDECQ+ G C NT GS+ C+C YV +GT C+ + E +L
Sbjct: 1 IDECALNSSLCVKNAHCVNTPGHYDCSCNAGFRGNGFIDCQESTCLHEDECSVKNNPCLSVNNSFCNNSIGSYSCICTSGYNGTTCEVTDINECISGQNNCPVNANCTNTIGSYTCACKLGYE--GNGWNCKDID--ECMTGNHCNSNGSECMNTDGSYYCTCALGFTGNGTYCA-DINECTANPYLCQDTEECMNGIGSYKCECLPGYIRNGTICTDVDEC--KKSQPCDANTMVCSNTIGSYTCLCKAGYQFDSTARICTDTDECVVSSLNNCSRTTGLCQNF----DGSFTCQCKAGYTGDGVTCTGKLCFHVVGVPQCRGAVILCNLAVGVVLLCDFTPIKLYKKKVFDVDECNPPENATQPCK-GPVGDLYGRDDAHCVCPDVDECIRGLHNCTQNCTNIEGGFTCSCFARF--SSVNGTCKRKFHLSTSFVHVAYVYTLWPSTDTIGSFKCGCVAGYAVVSDSRTC-QDVDECQSGIYNCTQYSTCRNLEGNYTCICNSGYESAHSIPTQGVYSFEFKHSNLSPP---------------PQPPESGETCIDVDECQKAGSALCGHGAYCANTLGSYACRCLVGYVG--NGTVCLDVDECLL 576 HSP 7 Score: 85.8853 bits (211), Expect = 2.795e-17 Identity = 92/306 (30.07%), Postives = 127/306 (41.50%), Query Frame = 1
Query: 2182 INECKKYSHIC--EHFCMNTEGSYKCSCMPGF----ILSANSHSC--QSVCSLCKNGKCDFNNK----------CKCKTGWTGELCDV-DIDECLLNQHKC--QHNCVNSNGSYSCSCNLPFY---LSTVDGRSCLEKNDSCSSPCKNGGKCVNSK----CKCKPGYNGDSCE-EDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLK 3012
I+EC S +C C+NT G Y CSC GF + +C + CS+ N NN C C +G+ G C+V DI+EC+ Q+ C NC N+ GSY+C+C L + + D C+ N C+S NG +C+N+ C C G+ G+ DINEC EC N G+Y+C C PGY+ NG +C DVDEC++ PCD +C NT GS+ C C + Y C E V+
Sbjct: 1 IDECALNSSLCVKNAHCVNTPGHYDCSCNAGFRGNGFIDCQESTCLHEDECSVKNNPCLSVNNSFCNNSIGSYSCICTSGYNGTTCEVTDINECISGQNNCPVNANCTNTIGSYTCACKLGYEGNGWNCKDIDECMTGNH-CNS---NGSECMNTDGSYYCTCALGFTGNGTYCADINECTANPYLCQDTEECMNGIGSYKCECLPGYI---------------------RNGTIC------------------TDVDECKKSQPCDANTMVCSNTIGSYTCLCKAGYQFDSTARICTDTDECVVS 263
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO46243 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQW9]) HSP 1 Score: 207.994 bits (528), Expect = 1.490e-56 Identity = 220/708 (31.07%), Postives = 310/708 (43.79%), Query Frame = 1
Query: 1015 SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKS---CIKEECSKFGT-TEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG----DCLNGI-CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE-----DKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI---LSANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHG--CIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
S C+NG TC C C GF G C EI+ C+ N C + N F C C+ GF + G C C T T+ ++G C CK G+ GK C ++DEC C+ C + I + C+C+ GFT G C +N KNG D +NG C C G+ G+DC +IDEC N C++ C + F C C GFT + + I + + C NG C C C PG+ G +C +PC++ CT + C+C PG+ D + C C TC + C C GF G C +I+EC + C++ CT+ I F C CK G + D+ + P N TC D+ ++G C CK G+ GK C +I+EC C + + C+C PGF C S + CKNG + C CK G+TG+ C +IDEC N K C + ++C+C F G+ C + D C+S PCKNG C + C CKPG+ G C +I+EC K+G C + Y C C PG+ + C+ + + +P C NGG+C DM C CP G+ GI C +D+DEC +PC + G C + +F C C Y +
Sbjct: 10 SNPCKNGATCTDRINGFTCTCKHGFTGKDCGTEIDECASKPCKNG---ATCTDR-INGFTCTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNP-CKNGATCTDRINGFACTCKPGFTGKDCGTE-IDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKN--GATCTDRINGFACTCKPGFTGKDCGTEIDECASN-PCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDR--INGF----ACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECAS--NPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFT-----GKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINDLINGYYCFCTPGFSGIH----CEANIDECASSP-CQNGGLCTDMINAFTCTCPPGYTGITCDIDIDECAS-SPC-QNGGFCTDMINAFTCSCPPGYTGIT 688 HSP 2 Score: 200.675 bits (509), Expect = 5.386e-54 Identity = 222/708 (31.36%), Postives = 310/708 (43.79%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKS---CIKEECSKFGT-TEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG----DCLNGI-CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE-----DKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI---LSANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS--------KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGV 2859
C +G + R F+C C T +C E+ C SK C+NG TC C C GF G C EI+ C+ N C + N F C C+ GF + G C C T T+ ++G C CK G+ GK C ++DEC C+ C + I + C+C+ GFT G C +N KNG D +NG C C G+ G+DC +IDEC N C++ C + F C C GFT + + I + + C NG C C C PG+ G +C +PC++ CT + C+C PG+ D + C C TC + C C GF G C +I+EC + C++ CT+ I F C CK G + D+ + P N TC D+ ++G C CK G+ GK C +I+EC C + + C+C PGF C S + CKNG + C CK G+TG+ C +IDEC N K C + ++C+C F G+ C + D C+S PCKNG C + C C PG++G CE +I+EC ++G G C + + C CPPGY + TC I + +P C NGG C DM C CP G+ GI C +
Sbjct: 13 CKNGATCTDRINGFTCTCKHGFTGKDCGTEIDECASKPCKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASNPCKNG---ATCTDR-INGFTCTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNP-CKNGATCTDRINGFACTCKPGFTGKDCGTE-IDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKN--GATCTDRINGFACTCKPGFTGKDCGTEIDECASN-PCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDR--INGF----ACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECAS--NPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFT-----GKDCGTEIDECASNPCKNGATCTDRINDLINGYYCFCTPGFSGIHCEANIDECASSPCQNG--GLCTDMINAFTCTCPPGYTGI----TCDIDIDECASSP-CQNGGFCTDMINAFTCSCPPGYTGITCDI 691 HSP 3 Score: 155.992 bits (393), Expect = 2.711e-39 Identity = 194/650 (29.85%), Postives = 281/650 (43.23%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKS---CIKEECSKFGT-TEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG----DCLNGI-CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE-----DKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI---LSANSHSCQSVCSLCKNGKC------DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCE 2616
C C+ G+ G+ C E + C C +G + R F+C C T +C E+ C S C+NG TC C C GF G C EI+ C+ N C + N F C C+ GF + G C C T T+ ++G C CK G+ GK C ++DEC C+ C + I + C+C+ GFT G C +N KNG D +NG C C G+ G+DC +IDEC N C++ C + F C C GFT + + I + + C NG C C C PG+ G +C +PC++ CT + C+C PG+ D + C C TC + C C GF G C +I+EC + C++ CT+ I F C CK G + D+ + P N TC D+ ++G C CK G+ GK C +I+EC C + + C+C PGF C S + CKNG D N C C G++G C+ +IDEC + + C + +++C+C + T D ++ ++ SSPC+NGG C + C C PGY G +C+
Sbjct: 66 CTCKPGFTGKDCG-TEIDECASNP---CKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNG---ATCTDR-INGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNP-CKNGATCTDRINGFACTCKPGFTGKDCGTE-IDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKN--GATCTDRINGFACTCKPGFTGKDCGTEIDECASN-PCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDR--INGF----ACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECAS--NPCKNGATCTDRINDLINGYYCFCTPGFSGIHCEANIDECASSPCQNGGLCTDMINAFTCTCPPGYTGITCD----IDIDECASSPCQNGGFCTDMINAFTCSCPPGYTGITCD 690 HSP 4 Score: 132.494 bits (332), Expect = 9.821e-32 Identity = 153/519 (29.48%), Postives = 206/519 (39.69%), Query Frame = 1
Query: 1522 CSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI---LSANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGT 2979
C +IDEC N C++ C + F C C GFT + +C SK C NG C C C PG+ G +C +PC++ CT + C+C PG+ D + C C TC + C C GF G C +I+EC + CKNG TC D+ ++G C CK G+ GK C +I+EC C + + C+C PGF C S + CKNG + C CK G+TG+ C +IDEC N K C + ++C+C F G+ C + D C+S PCKNG C + C CKPG+ G C +I+EC K+G C + + C C PG+ D C + NP C NG C D C C GF G DCG ++DEC PC K C + F C C + GT
Sbjct: 1 CGTEIDECASNP-CKNGATCTDRINGFTCTCKHGFTGKDCGTEIDECASKPCK----NGATCTDRINGFTCTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASNPCKN--GATCTDRINGFACTCKPGFTGKDCGTEIDECASN----------------PCKNGA---------------TCTDR--INGF----ACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECAS--NPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFT-----GKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNG--ATCTDRINGFACTCKPGFTGKD----CGTEIDECASNP-CKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASN-PC-KNGATCTDRINGFACTCKPGFTGKDCGT 459 HSP 5 Score: 132.109 bits (331), Expect = 1.303e-31 Identity = 168/567 (29.63%), Postives = 244/567 (43.03%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKS---CIKEECSKFGT-TEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG----DCLNGI-CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE-----DKRSCIP-PNKKTCLDK--DCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGK--CDFNNK--CKCKTGWTGELCDV 2391
C C+ G+ G+ C E + C C +G + R F+C C T +C E+ C S C+NG TC C C GF G C EI+ C+ N C + N F C C+ GF + G C C T T+ ++G C CK G+ GK C ++DEC C+ C + I + C+C+ GFT G C +N KNG D +NG C C G+ G+DC +IDEC N C++ C + F C C GFT + + I + + C NG C C C PG+ G +C +PC++ CT + C+C PG+ D + C C TC + C C GF G C +I+EC + C++ CT+ I F C CK G + D+ + P N TC D+ D ++G C C G+ G C+ +I+EC C + ++ C+C PG+ ++ + + S C+NG D N C C G+TG CD+
Sbjct: 142 CTCKPGFTGKDCG-TEIDECASNP---CKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNG---ATCTDR-INGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNP-CKNGATCTDRINGFACTCKPGFTGKDCGTE-IDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKN--GATCTDRINGFACTCKPGFTGKDCGTEIDECASN-PCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINDLINGY----YCFCTPGFSGIHCEANIDECASSPCQNGGLCTDMINAFTCTCPPGYTGITCDIDIDECASSPCQNGGFCTDMINAFTCSCPPGYTGITCDI 691
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO39165 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB01]) HSP 1 Score: 213.001 bits (541), Expect = 1.811e-56 Identity = 231/768 (30.08%), Postives = 336/768 (43.75%), Query Frame = 1
Query: 955 FSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGN-RTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT-TEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFT---LQINKKKCISKSCNI--ECLNGGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEH-NCTTINDNMVCSCLP---------------------GYDLMPDKKTCKKLECPKCVRG-------------------TC----NENKCKCPKGFAGLLCENDINECLNQTICQHV-CTNTIGSFFCRCK---NGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN---------KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
F+C+C + C +++ CS C NGG C G +C C GF G+ CQ+ I+ C+ N TCE + V+E F+C+CQ GF+ N + CI C+ T ++V+ C C G+ G+ C+ D+DEC CQ C++ + SYQC C+ G+T C I+ CL+ C NG CL+ + C C +G+ G+DCS++ID+C + C+H C+++ + C C G+T I+ +C S C CLN L + C C GY G NCE + D C F +PC + C + +N C C G + T ECPK G TC N C CP+GF G LC+ +++EC + C + I F C C G A D C CL++ +C C+SGY G RC+ DI+EC + C++ ++C C PG+ C+ C N C N C C G+TG C+V+ID+C + + +C + Y C C F G C D C++ PC N G CV+ C CKPG+ G CE +I++C + I C + ++ C CP GY +TC I+ D P C GG C D C C GF GI+C +++DEC Y PC G C + C C+ + +
Sbjct: 150 FNCLCRHGYSGITCEVDVNECSSSPCVNGGVCADGLGEYKCICPSGFSGENCQVNIDECASSPCKNGATCEDL-VDE----FRCQCQPGFKGQNCETNINECIGAACANGSTCIDLVNAYQCTCLPGFTGRHCDVDIDECQSNPCQHGSACMDGVSSYQCICQPGYT---GQYCHIDIDECLSRPCLNNGMCLDLVSDFHCTCPTGFSGKDCSVNIDDCA-DAPCQHGSTCIDLVNDYKCSCLQGYTGKDCHIDINECSSNPCQYGGTCLN--LLNGYACLCIDGYTGLNCEKDIDDCLF-NPCHNGTCEDLVNNYKCVCPDNRQERTCAGNSSVCDTYLCRNGGSCFSNNSTYYTCECPKGYTGHDCESKINYCKSSSCYGNATCLDGANNYTCICPRGFTGTLCDVNVDECEDSPCANGASCEDLINDFRCHCPAGFQGRTCAVDINECA---TSPCLNEAKCTDVVSGYRCTCRSGYTGTRCERDIDECSSSPCVNGGLCVDYTNYFECLCHPGY----GGDRCEINIDDCANKPCLHNGNCTDYVNYFTCACAVGYTGRTCEVNIDDCSPSPCRHGGSCQDLVNGYLCHCPAGF-----KGSKCETDIDECATNPCDNNGTCVDRVASYDCVCKPGFTGTRCEANIDDCATSPCLNNAI--CTDLINDFHCACPAGY----QGQTCAINVDDCTPQP-CKQGGTCVDAVSGYTCLCMPGFTGINCSIEMDECGSY-PCLN-NGTCVDGRNRVTCTCAVGFTGQF 884 HSP 2 Score: 204.142 bits (518), Expect = 1.198e-53 Identity = 224/789 (28.39%), Postives = 335/789 (42.46%), Query Frame = 1
Query: 802 CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICV-NEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT-TEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN-----GDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSC---NIECLNGGLCDKD-----KCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPKCVRGT-----CNENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI---LSANSHSCQSVCSLCKNGKC--DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVC---RDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMT 2991
C G+C +C C +G+ GE C + E C +G + + +F C C NC + C C NG TC +C C GF G C ++I+ C + C+H +G +++QC CQ G+ D C+ C G ++VS +C C G+ GK C+ ++D+C CQ C++ + Y+CSC +G+T C I+ +N C+ N G CLN + C C G+ G +C DID+C +N C ++ ++ C C ++ C S C NGG C + C+CP GY GH+CE ++C S C N T ++ +N C C G+ + E C G N+ +C CP GF G C DINEC + + CT+ + + C C++G+ +R + C++ +C+C GY G RC+ +I++C + C + + C+C G+ N C S C++G D N C C G+ G C+ DIDEC N CV+ SY C C F G C D C+ SPC N C + C C GY G +C ++++C K G G C + Y C+C PG+ ++ C I + P CLN G C R+ C C +GF G C V++D+C APC G C + F C C + G +C T
Sbjct: 175 CVNGGVCADGLGEYKCICPSGFSGENCQVNIDECASSP----CKNGATCEDLVDEFRCQCQPGFKGQNCETNINECIGAACANGSTCIDLVNAYQCTCLPGFTGRHCDVDIDECQ-----SNPCQHGSACMDGVSSYQCICQPGYTGQYCHIDIDECLSRPCLNNGMCLDLVSDFHCTCPTGFSGKDCSVNIDDCADAPCQHGSTCIDLVNDYKCSCLQGYT---GKDCHID-INECSSNPCQYGGTCLNLLNGYACLCIDGYTGLNCEKDIDDCLFNPCHNGTCEDLVNNYKCVCPD----NRQERTCAGNSSVCDTYLCRNGGSCFSNNSTYYTCECPKGYTGHDCESKINYCKS-SSCYGNATCLDGANNYTCICPRGFTGTLCDVNVDECEDSPCANGASCEDLINDFRCHCPAGFQGRTCAVDINECATSPCLNEAKCTDVVSGYRCTCRSGYTGTRCERDIDECSSSPCVNGGLCVDYTNYFECLCHPGYGGDRCEINIDDCANKPCLHNGNCTDYVNYFTCACAVGYTGRTCEVNIDDCSP--SPCRHGGSCQDLVNGYLCHCPAGFKGSKCETDIDECATNPCDNNGTCVDRVASYDCVCKPGFT-----GTRCEANIDDCATSPCLNNAICTDLINDFHCACPAGYQGQTCAINVDDCTPQPCKQG--GTCVDAVSGYTCLCMPGFTGIN----CSIEMDECGSYP-CLNNGTCVDGRNRVTCTCAVGFTGQFCEVNIDDCDP-APCQNY-GTCQDLVADFTCHCYPGFT----GETCAT 925 HSP 3 Score: 204.142 bits (518), Expect = 1.274e-53 Identity = 227/772 (29.40%), Postives = 330/772 (42.75%), Query Frame = 1
Query: 1024 CQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ---LDNDGKSCIKEECSKFGTTE--VVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN-----GDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN--DNMVCSCLPGY------------------------DLMPDKK-TCK--------KLECPKCVRGTC----------NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHK-----------------------LAEDKRSCIPPNK--KTCLDKDCV--------HGQCFNS-----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKC--DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C NGGTC +G C C GF G C+ +++ C Q N C+++ N+F+C C GF + + C C T + + +C+C QG G+ CN D+DEC C Q C N +G + C CR G++ ++ C ++ +N C+ + G C +G+ C C SG+ GE+C ++IDEC + C++ C ++ F CQC GF Q N +CI +C L + +C C PG+ G +C+ + D C +PC+H ++ + C C PGY DL+ D TC + C C N+ KC C +G+ G C DINEC + CQ+ C N + + C C +G+ L + + P N+ +TC V G CF++ C C GY G C+ IN CK S C++ +Y C C GF + N C+ S C NG D N +C C G+ G C VDI+EC + + C + Y C+C S G C D C SSPC NGG CV+ +C C PGY GD CE +I++C H G C + + C C GY +TC+++ D +P C +GG C+D+ C+CP GF G C D+DEC PCD G C + S+ C C +
Sbjct: 23 CLNGGTCSEGSNSLLCSCLPGFTGQSCETDVDECKLVQCHNGA---TCIDQ-VNSFKCICPVGFHGILCETNYNDCHSNPCQNNATCQDLINDFSCQCPQGITGQTCNTDIDECQSSPCKHQGTCQNYLGGFNCLCRHGYSGIT---CEVD-VNECSSSPCVNGGVCADGLGEYKCICPSGFSGENCQVNIDECA-SSPCKNGATCEDLVDEFRCQCQPGFKGQNCETNINECIGAACANGSTCIDLVNAYQCTCLPGFTGRHCDVDIDECQS-NPCQHGSACMDGVSSYQCICQPGYTGQYCHIDIDECLSRPCLNNGMCLDLVSDFHCTCPTGFSGKDCSVNIDDCADAPCQHGSTCIDLVNDYKCSCLQGYTGKDCHIDINEC-SSNPCQYGGTCLNLLNGYACLCIDGYTGLNCEKDIDDCLFNPCHNGTCEDLVNNYKCVCPDNRQERTCAGNSSVCDTYLCRNGGSCFSNNSTYYTCECPKGYTGHDCESKINYCKSSSCYGNATCLDGANNYTCICPRGFTGTLCDVNVDECED--SPCANGASCEDLINDFRCHCPAGFQGRTCAVDINECATSPCLNEAKCTDVVSGYRCTCR-----SGYTGTRCERDIDECSSSPCVNGGLCVDYTNYFECLCHPGYGGDRCEINIDDCANKPCLHN--GNCTDYVNYFTCACAVGYT----GRTCEVNIDDCSPSP-CRHGGSCQDLVNGYLCHCPAGFKGSKCETDIDECAT-NPCDN-NGTCVDRVASYDCVCKPGFT 767 HSP 4 Score: 156.377 bits (394), Expect = 1.218e-38 Identity = 193/707 (27.30%), Postives = 293/707 (41.44%), Query Frame = 1
Query: 1024 CQNGGTCFQG-----RCQCTEGFEGDQCQLEINSC-SRGQMGNRTCEHICVNEGENNFQCKCQSGFQ---LDNDGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHL--CVNVPGSFNCQCHSGFT---LQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTC-----NENKCKCPKGFAGLLCENDINECLNQTICQH-VCTNTIGSFFCRCKNGH-----KLAEDKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHF--CMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK----------CKTGWTGELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKT---CQISTKDT-MCNPH--CLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCS 2949
C+NGG+CF C+C +G+ G C+ +IN C S GN TC +G NN+ C C GF D + C C+ + E + + C C G++G+ C D++EC C + C + + Y+C+CR G+T + C ++ C G C++ C C G+ G+ C ++ID+C N C H C + F C C G+T ++N C C L + C CP G+ G CE + +PC++N T ++ + C C PG+ + C+ N+ C CP G+ G C ++++C Q Q C + + + C C G + D+ P N TC+D C C G+ G+ C+ +I++C C+++ C + + C C PGF +C + LC+ C N C+ C TG TG CDV I + C++N CV + Y C C S+ C D C + C NG CV+S KC C GY G CE I+ C ++G C + G C C G+ +K C + DT + P C + G C C C GF G+ C D+D+C PC + C + +F CQ S
Sbjct: 478 CRNGGSCFSNNSTYYTCECPKGYTGHDCESKINYCKSSSCYGNATCL-----DGANNYTCICPRGFTGTLCDVNVDECEDSPCANGASCEDLINDFRCHCPAGFQGRTCAVDINECATSPCLNEAKCTDVVSGYRCTCRSGYTGTRCERDIDECSSSPCVNGGLCVDYTNYFECLCHPGYGGDRCEINIDDCA-NKPCLHNGNCTDYVNYFTCACAVGYTGRTCEVNIDDCSPSPCRHGGSCQDLVNGYLCHCPAGFKGSKCETDIDECATNPCDNNGTCVDRVASYDCVCKPGFTGTRCEANIDDCATSPCLNNAICTDLINDFHCACPAGYQGQTCAINVDDCTPQPCKQGGTCVDAVSGYTCLCMPGFTGINCSIEMDECGSYPCLNNGTCVDGR------NRVTCTCAVGFTGQFCEVNIDDCDPAP--CQNYGTCQDLVADFTCHCYPGFT----GETCATPIDLCEAHPCQNNATCRMDPLKGYSCSCPTGVTGRHCDVSI----CDSKPCRNNGSCVLTQSGYQCLC-----ASSFTSPQCQRSIDDCEHAHCLNGATCVDSDNAYKCSCLEGYYGKHCEL-IDRCHSQPCQNG--ATCVDDDGVVFCKCAMGFTGTHCEKEFNHCIVRVADTNLTFPSRICGDHGTCVSKPTGFLCVCQPGFTGLLCQTDIDDCSS-DPCVGINVTCVDGIDTFTCQSS 1153 HSP 5 Score: 147.902 bits (372), Expect = 5.568e-36 Identity = 163/522 (31.23%), Postives = 244/522 (46.74%), Query Frame = 1
Query: 1450 NNCNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGF---TLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTC-----NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQ-CFN----SKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFI---LSANSHSCQSVCSLCKNGKC-----DFNNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPH-CLNGGVC----RDMSRCYCPIGFHGIDCGVDVDECQ 2877
++C G C G +C C G+ G+ C D+DECK C + C++ SF C C GF + N C S C L + C+CP G G C + D C SPC+H T N C C GY + + + CV G E KC CP GF+G C+ +I+EC + + C++ C + + F C+C+ G K ++C N C+ C +G C + +C C G+ G+ CD DI+EC+ S+ C+H CM+ SY+C C PG+ + C S L NG C DF+ C C TG++G+ C V+ID+C CQH C++ Y CSC L G+ C ++ N+ S+PC+ GG C+N C C GY G +CE+DI++C + + G C + NY+C+CP D+++ + ++C+ + C NGG C C CP G+ G DC ++ C+
Sbjct: 21 DSCLNGGTCSEGSNSLLCSCLPGFTGQSCETDVDECKLVQ-CHNGATCIDQVNSFKCICPVGFHGILCETNYNDCHSNPCQNNATCQDLINDFSCQCPQGITGQTCNTDIDECQS-SPCKHQGTCQNYLGGFNCLCRHGYSGITCEVDVNECSSSPCVNGGVCADGLGEYKCICPSGFSGENCQVNIDECAS-SPCKNGATCEDLVDEFRCQCQPGFK----GQNC-ETNINECIGAACANGSTCIDLVNAYQCTCLPGFTGRHCDVDIDECQ--SNPCQHGSACMDGVSSYQCICQPGYTGQYCHIDIDECLSRPCL-NNGMCLDLVSDFH--CTCPTGFSGKDCSVNIDDCA--DAPCQHGSTCIDLVNDYKCSC-----LQGYTGKDCHIDINECSSNPCQYGGTCLNLLNGYACLCIDGYTGLNCEKDIDDCLFNPCHN---GTCEDLVNNYKCVCP------DNRQERTCAGNSSVCDTYLCRNGGSCFSNNSTYYTCECPKGYTGHDCESKINYCK 513 HSP 6 Score: 138.658 bits (348), Expect = 4.089e-33 Identity = 134/424 (31.60%), Postives = 200/424 (47.17%), Query Frame = 1
Query: 1786 CTTINDNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVH-GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI---LSANSHSCQSVCSLCKNGKC--DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
C+ +++++CSCLPG+ D CK ++C C+ N KC CP GF G+LCE + N+C + CQ+ C + I F C+C G ++C + C C H G C N C+C+ GY G C+ D+NEC + C + G YKC C GF N C S S CKNG D + +C+C+ G+ G+ C+ +I+EC+ C++ +Y C+C LP + GR C D C S+PC++G C++ +C C+PGY G C DI+EC C+ G C + ++ C CP G+ K C ++ D P C +G C D+ +C C G+ G DC +D++EC PC + G C N + C C Y +
Sbjct: 29 CSEGSNSLLCSCLPGFTGQSCETDVDECKLVQCHNGATCIDQV-NSFKCICPVGFHGILCETNYNDC-HSNPCQNNATCQDLINDFSCQCPQGIT----GQTC-NTDIDECQSSPCKHQGTCQNYLGGFNCLCRHGYSGITCEVDVNECSSSPCVNGGVCADGLGEYKCICPSGFSGENCQVNIDECAS--SPCKNGATCEDLVDEFRCQCQPGFKGQNCETNINECIGAACANGSTCIDLVNAYQCTC-LPGFT----GRHCDVDIDECQSNPCQHGSACMDGVSSYQCICQPGYTGQYCHIDIDECL----SRPCLNNGMCLDLVSDFHCTCPTGF----SGKDCSVNIDDCADAP-CQHGSTCIDLVNDYKCSCLQGYTGKDCHIDINECSS-NPC-QYGGTCLNLLNGYACLCIDGYTGL 427 HSP 7 Score: 122.094 bits (305), Expect = 5.415e-28 Identity = 179/708 (25.28%), Postives = 274/708 (38.70%), Query Frame = 1
Query: 925 GCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGN-RTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKE--ECS------KFGTTEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN--------CLNN----------------------------------CNKNGDC---LNG-ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFT---LQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLM---PDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNG---------------HKLAEDKRSCIPPNK-----------------KTCLDKDCVH-GQCFNSK----CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF-------ILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIG 2667
G F ++C C T ++C ++ C S C TC G C C GF G C + ++ C N +CE + N+F+C C +GFQ G++C + EC+ + T+VVSG C C+ G+ G C D+DEC C +CV+ ++C C G+ +C IN CL+N C G C +NG +C+C +G+ G C DIDEC N C++ CV+ S++C C GFT + N C + C + L + C CP GY G C N PC+ T ++ C C+PG+ + + C C CV G N C C GF G CE +I++C + CQ+ C + + F C C G H + + P K C K C + G C ++ C+C S + +C I++C+ + C++++ +YKCSC+ G+ I +S CQ+ + + F CKC G+TG C+ + + C++ NL F S C + G CV+ C C+PG+ G C+ DI++C S C+G
Sbjct: 482 GSCFSNNSTYYTCECPKGYTGHDCESKINYCKSSSCYGNATCLDGANNYTCICPRGFTGTLCDVNVDECEDSPCANGASCEDLI-----NDFRCHCPAGFQ----GRTCAVDINECATSPCLNEAKCTDVVSGYRCTCRSGYTGTRCERDIDECSSSPCVNGGLCVDYTNYFECLCHPGY---GGDRCEINIDDCANKPCLHNGNCTDYVNYFTCACAVGYTGRTCEVNIDDCSPSPCRHGGSCQDLVNGYLCHCPAGFKGSKCETDIDECATNP-CDNNGTCVDRVASYDCVCKPGFTGTRCEANIDDCATSPCLNNAICTDLINDFHCACPAGYQGQTCAINVDDCTPQPCKQGGTCVDAVSGYTCLCMPGFTGINCSIEMDECGSYPCLNNGTCVDGR-NRVTCTCAVGFTGQFCEVNIDDC-DPAPCQNYGTCQDLVADFTCHCYPGFTGETCATPIDLCEAHPCQNNATCRMDPLKGYSCSCPTGVTGRHCDVSICDSKPCRNNGSCVLTQSGYQCLCASSFTSPQCQRSIDDCEHAHCLNGATCVDSDNAYKCSCLEGYYGKHCELIDRCHSQPCQNGATCVDDDGVVF---CKCAMGFTGTHCEKEFNHCIVRVAD---------------TNLTFP----------------SRICGDHGTCVSKPTGFLCVCQPGFTGLLCQTDIDDC----SSDPCVG 1136
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO48851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHH9]) HSP 1 Score: 208.764 bits (530), Expect = 5.431e-55 Identity = 232/713 (32.54%), Postives = 327/713 (45.86%), Query Frame = 1
Query: 1000 ELRTCSKG-CQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSG--NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG----------ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCI---SKSCN----IECLN-GGLCDKDKCKCPPGYIGH--NCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTC-NEN---KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF--------ILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
++ CSK CQNGG C C C GF G C+ ++N C++ N +C NE + C C++GF N D C K C G + G +C CK G+ GK C DV+EC CQ +C N G Y C+C+ GFT GK +N C+KN C NG C C +G+ G+ C +I CE + PG + + +K C K+C+ I N GG + + P ++ + N EF + C PC++ C +N C+C G+ + D C K C G C NE+ C C GF G CE D+NEC N+ CQ+ VC N G + C CK G ++ +K C + + C CK+G+ GK C++D+NEC K C N G Y C+C GF + + + CQ+ +CKN ++ C CK G+TG+ C+ D++EC N K C N +G YSC+C F G+ C + + CS +PCKNGG C N C CK G+ G +CE+D+NEC K+G G C+N G Y C C G+ K C+ + NP C NGGVC++ C C GF G +C DV+EC + PC K G+C N +G + C C + +
Sbjct: 726 DVNECSKNPCQNGGVCKNEHGGYSCACKAGFTGKICEQDVNECNKNPCQNGG---VCKNE-HGGYSCTCKAGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYSCTCKAGFT----GKNCEQDVNECSKN-PCKNGGVCKNEHGGYSCACKAGFTGKICEQEI--------CEICGTHAPGWMEGSHPTVAEGIVTRKVCYHWSGKTCHWNNAIRVRNCGGFYVYELNRPPVCHLRYCGNAEF-ETCS-SKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSKNPCKN--GGVCKNEHGGYSCACKAGFTGKNCEQDVNEC-NKNPCQNGGVCKNEHGGYSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDMNECSKNPCQNG-GVCKNKHGGYS--CACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGF-----TGKICEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNG--GVCKNEHGGYSCTCKAGFT----GKNCEQDVNECSKNP-CKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSK-NPC-KNGGVCKNEHGGYSCTCKAGFT 1399 HSP 2 Score: 189.119 bits (479), Expect = 9.269e-49 Identity = 236/772 (30.57%), Postives = 328/772 (42.49%), Query Frame = 1
Query: 955 FSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSG--NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLL-----------SNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDC----SLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTC-NEN---KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSL--CKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHG------------------------------IDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVL 3009
+SC C T C ++ C+K CQNGG C C C GF G C+ ++N C++ N +C NE + C C++GF N D C K C G + G +C CK G+ GK C DV+EC C+ +C N G Y C+C+ GFT ++ + + G +CY W G+ C ++ + C + E +N P CH + + C SK C NGG C + C C G+ G NCE + +PC++ C + C+C G+ + D C K C G C NE+ C C GF G CE D+NEC ++ CQ+ VC N G + C CK G ++ +K C + + C CK+G+ GK C++D+NEC K C N G Y C+C GF N + CS CKNG N C CK G+TG++C+ D++EC N K C N +G YSC+C F G++C + + CS +PCKNGG C N C CK G+ G +CE+D+NEC K+G G C+N G Y C C G+ K C+ + NP C NGGVC++ C C GF G ++ D +EC + PC G C NT GS+ C C + Y G C T K L
Sbjct: 748 YSCACKAGFTGKICEQDVNECNKNPCQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECNKNPCQNGG---VCKNE-HGGYSCTCKAGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKICEQEICEICGTHAPGWMEGSHPTVAEGIVTRKVCY---HWSGKTCHWNNAIRVRNCGGFYVYE---LNRPPV----CHLRYCGNAEFETCSSKPCK----NGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECNKNPCQN--GGVCKNEHGGYSCACKAGFTGKNCEQDMNEC-SKNPCQNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKNKHGGYSCACKAGFT-GKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKICEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGF-----TGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNG--GVCKNEHGGYSCTCKAGFT----GKNCEQDVNECSKNP-CKNGGVCKNEHGGYSCTCKAGFTGKTANKMLTNVPASTRVIMAESALTAMEDTVVNARPDKNEC-KVNPCLN-NGKCINTPGSYKCNC----IDEYTGKHCETAKYKEL 1479 HSP 3 Score: 186.808 bits (473), Expect = 4.469e-48 Identity = 258/938 (27.51%), Postives = 390/938 (41.58%), Query Frame = 1
Query: 520 YVWDEIGKYW--TYKLRHHQSYPDFNFNEFPNSPCKPPFCLPRRCDQIDCGQSNCITNSRPCARNNQDCSMEQKRVLFGSEVVCLNK---PAIDNC-VPDCGEHGICVKSR----CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCS-KGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSG--NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG----------ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGY-----DLMPDK----KTCKKLECPKCVRGTCNENKCKCPK------------GFAGLLCEND---INECLNQ----------TICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF--------ILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINEC------QWPISKHGCIGE-----------------------CRN--TFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCY---CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
Y W +W ++R+ + + N +PP C R C + + C N PC +N C E +V K ++ C V C G+C C C+ G+ G+ C E + C +G +SC C + T NC ++ CS C+NGG C C C GF G C+ ++N CS+ N +C NE + C C++GF N D C K C G + G +C CK G+ GK C DV+EC CQ +C N G Y C+C+ GF GK +N C+KN C NG C C +G+ G++C D++EC N C++ +C N G ++C C +GFT + ++ + +++ + G+C + C C G+ G NCE + ++PC++ C + C+C G+ + P K ++ KKL+ G N KC + G AG IN C T+ + + T + + D C +K C + + C CK+G+ GK C++D+NEC K C N G Y C+C GF + N + CQ+ +CKN ++ C CK G+TG+ C+ D++EC N++ CQ+ C N +G YSC+C F G++C + + CS +PCKNGG C N C CK G+ G CE++I E W H + E RN F YE PP + + C + +T + C NGG CR+++ Y C GF G +C DV+EC + PC K G+C N +G + C C + +
Sbjct: 173 YHWSGKTCHWNNAIRVRNCGGFYVYELN-------RPPVCHLRYCGNAEFDVNECSKN--PC-KNGGVCKNEHGGYSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNEC----SVNPCKNGGVCKNEHGGYSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGG---VCKNE-HGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCQNGGVCKNEHGGYSCACKAGFM----GKNCEQDVNECSKN-PCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNP-CKNGGVCKNEHGGYSCACKAGFTGKNCEQDGLKTIIHLQSIKCGVCKNEHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQAPSKPRECRSYKKLDTADRAAGRPRGNVLKCDQKEILTKAWYRFEGAAGSAMPTSLVPINRCGTHAPGWMEGSHPTVAEGIVTRKVCYHW----------SDVNEC---SKNPCQNGGVCKNEHGGYSCACKAGFTGKICEQDVNECNKNPCQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECNKNPCQNG-GVCKNEHGGYS--CTCKAGFTGKNCEQDVNEC--NKNPCQNGGVCKNEHGGYSCTCKAGF-----TGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKICEQEICEICGTHAPGWMEGSHPTVAEGIVTRKVCYHWSGKTCHWNNAIRVRNCGGFYVYELNRPP----VCHLRYCGNAEFETCSSKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSK-NPC-KNGGVCKNEHGGYSCACKAGFT 1057 HSP 4 Score: 163.696 bits (413), Expect = 7.852e-41 Identity = 180/593 (30.35%), Postives = 264/593 (44.52%), Query Frame = 1
Query: 1321 DDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG----------ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTI-----------GSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS-----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
DV+EC CQ +C N G Y C+C+ GFT GK +N CNKN C NG C C +G+ G++C D++EC N C++ +C N G ++C C +GFT + N ++ +++ C NGG+C + C C G+ G NCE + +PC++ C + C+C G+ K C++ C C + P G++ + +C H T G F+ N + R C +TC K C +G C CKSG+ GK C++D+NEC K C N G Y C+C K G+TG+ C+ D++EC N++ CQ+ C N +G YSC+C F G++C + + CS +PC+NGG C N C CK G+ G +CE+D+NEC K+G G C+N G Y C C G+ K C+ + NP C NGGVC++ C C GF G +C DV+EC + PC K G+C N +G + C C + +
Sbjct: 725 SDVNECSKNPCQNGGVCKNEHGGYSCACKAGFT----GKICEQDVNECNKN-PCQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECNKNP-CQNGGVCKNEHGGYSCTCKAGFTGK-NCEQDVNECNKNPCQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFT----GKICEQEICEICGTHAPGWMEGSHPTVAEGIV---------TRKVCYHWSGKTCHWNNAIRVRNCGGFYVYELNRPPVCH-LRYCGNAEFETCSSKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCAC---------------------------------KAGFTGKNCEQDVNEC--NKNPCQNGGVCKNEHGGYSCACKAGF-----TGKNCEQDMNECSKNPCQNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCKNG--GVCKNEHGGYSCACKAGFT----GKNCEQDMNECSKNP-CQNGGVCKNKHGGYSCACKAGFTGKNCEQDVNECSK-NPC-KNGGVCKNEHGGYSCTCKAGFT 1247 HSP 5 Score: 153.295 bits (386), Expect = 1.215e-37 Identity = 202/691 (29.23%), Postives = 286/691 (41.39%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQGR----CQCTEGFEGDQCQLEI-NSCSRGQMGNRTCEHICVNEG-----------------ENNFQCKCQSGFQL---------------DNDGKSCIKEECSKFGTTEVVSG--NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG----------ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSL--CKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSC--------------NLPFYLSTVDGRSCL------------EKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCE 2616
C C+ G+ G+ C E K C +G +SC C T NC ++ CSK C+NGG C C C GF G C+ EI C G H V EG N + + GF + + + ++C + C GT V+G +C CK G+ GK C DV+EC C+ +C N G Y C+C+ GFT GK +N CNKN C NG C C +G+ G++C D++EC N C++ +C N G ++C C +GFT + N ++ +++ C NGG+C + C C G+ G NCE + +PC++ N + GY C C GF G CE D+NEC ++ C++ VC N G + C CK G ++ +K C + + C CK+G+ GK C++D+NEC K C N G Y C+C GF N + CS CKNG N C CK G+TG+ C+ D++EC N K C N +G YSC+C N+P + S L +KN+ +PC N GKC+N+ KC C Y G CE
Sbjct: 826 CTCKAGFTGKNCEQDVNECNKNP----CQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKICEQEICEICGTHAPGWMEGSHPTVAEGIVTRKVCYHWSGKTCHWNNAIRVRNCGGFYVYELNRPPVCHLRYCGNAEFETCSSKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFT----GKNCEQDVNECNKN-PCQNGGVCKNEHGGYSCACKAGFTGKNCEQDMNECSKNP-CQNGGVCKNEHGGYSCACKAGFTGK-NCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKNKHG------GYS-------------------------CACKAGFTGKNCEQDVNEC-SKNPCKNGGVCKNEHGGYSCTCKAGFTGKICEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFT-GKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKTANKMLTNVPASTRVIMAESALTAMEDTVVNARPDKNECKVNPCLNNGKCINTPGSYKCNCIDEYTGKHCE 1472 HSP 6 Score: 152.525 bits (384), Expect = 2.412e-37 Identity = 155/486 (31.89%), Postives = 214/486 (44.03%), Query Frame = 1
Query: 1672 CLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCK---NGHKLAEDKRSC-IPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSL--CKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV------LMYDGTSCMTMKEAVLKPHLRYRGRGN 3042
C NGG+C + C C G+ G NCE + ++PC++ N++ GY C C GF G CE D+NEC +N VC N G + C CK G +D C + P K + K+ HG C CK+G+ GK C++D+NEC K C N G Y C+C GF N + CS CKNG N C CK G+TG+ C+ D++EC N + C N +G YSC+C F G++C + + CS +PCKNGG C N C CK G+ G +CE+D+NEC K+G G C+N G Y C C G+ K C+ T+ + + GVC++ C C GF G +C DV+EC PC K G+C N +G + C C + + C + K+ R RGN
Sbjct: 225 CKNGGVCKNEHGGYSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHG------GYS-------------------------CACKAGFTGKNCEQDVNECSVNPCKNGGVCKNEHGGYSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKN-EHG---GYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFT-GKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCQNGGVCKNEHGGYSCACKAGFM-----GKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCKNG--GVCKNEHGGYSCACKAGFT----GKNCEQDGLKTIIHLQSIKCGVCKNEHGGYSCACKAGFTGKNCEQDVNECS-VNPC-KNGGVCKNEHGGYSCACKAGFTGKNCEQAPSKPRECRSYKKLDTADRAAGRPRGN 661 HSP 7 Score: 149.443 bits (376), Expect = 1.747e-36 Identity = 222/774 (28.68%), Postives = 323/774 (41.73%), Query Frame = 1
Query: 751 SEVVCLNKPAIDNCVPD-CGEHGICVKSR----CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGTTEVVSG--NCKCKQGWKGKFCNDDV-----------DECLFP------VCQQICV----------NTIGSYQCSCREGFTLLSNGKCAINCLNN----------CNKNGDC--LNGI--CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTC-NEN---KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSL--CKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEE------------------------------DINECQWPISKHGCI--GECRNTFGNYECICPPGYL 2721
+ VC + ++ C + C G+C C C+ G+ G+ C E K C +G +SC C T NC ++ C+K CQNGG C C C GF G C+ ++N C++ N +C NE + C C++GF N D C K C G + G +C CK G+ GK C ++ E P V +++C N I C + L C + N C G C +NG C C SG+ G++C D++EC N C++ +C N G ++C C +GFT + N ++ +++ C NGG+C + C C G+ G NCE + +PC++ C + C+C G+ + D C K C G C NE+ C C GF G CE D+NEC ++ CQ+ VC N G + C CK G ++ +K C + + C CK+G+ GK C++D+NEC K C N G Y C+C GF N + CS CKNG N C CK G+TG+ C+ D++EC N K C N +G YSC+C F G++C + + CS +PCKNGG C N C CK G+ G + + D NEC+ + C+ G+C NT G+Y+C C Y
Sbjct: 717 TRKVCYHWSDVNECSKNPCQNGGVCKNEHGGYSCACKAGFTGKICEQDVNECNKNP----CQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECNKNPCQNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECNKNPCQNGG---VCKNE-HGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCACKAGFTGKICEQEICEICGTHAPGWMEGSHPTVAEGIVTRKVCYHWSGKTCHWNNAIRVRNCGGFYVYELNRPPVCHLRYCGNAEFETCSSKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSKNP-CKNGGVCKNEHGGYSCACKAGFTGK-NCEQDVNECNKNPCQNGGVCKNEHGGYSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCKN--GGVCKNEHGGYSCACKAGFTGKNCEQDMNEC-SKNPCQNGGVCKNKHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKICEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFT-GKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGF-----TGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKTANKMLTNVPASTRVIMAESALTAMEDTVVNARPDKNECKV----NPCLNNGKCINTPGSYKCNCIDEYT 1467
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO44398 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVK5]) HSP 1 Score: 178.333 bits (451), Expect = 1.036e-45 Identity = 200/668 (29.94%), Postives = 284/668 (42.51%), Query Frame = 1
Query: 1132 NRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGT-----TEVVSGNCKCKQGWKGKFCNDD-----VDECL--FPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG--------DCLNG-ICYCFSGWH----GEDCSLDIDEC---KYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGL-CDKD--------KCKCPPGY-----IGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLE--------CPKCVRGTCNENKCKCPKGF----AGLLCENDINEC---LNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGY-------------------------------------------RGKRCD----EDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCD-------FNNKCKCKTGWTGELCD-----VDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLST----VDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCE----EDINECQWPISKHG--CIGECRNTFGNYECICPPGYLVLDDQKTC 2745
N C +C+N N C C G+ L+ D +SC + T + N + D VDEC C+ +C+NT GS+ C CR+G+ L ++ K IN LN C D G C C G+ G C +D++EC K H C+H CVN PGS+ C C+ GF L N ++C + EC+ GG+ CD+ +C+C G+ + C D C P H CT + C+C GY + ++ C+ ++ C + T CKC G+ AG DI+EC + C H C NT GSF C C +G+ L +D +C + + +D H +C NS C C GY +G R D DI+ECK+ +CE C+NTEGSY C C PG+ L+ + CQ V CD + C+CKTG+ EL D+DEC LN C CVN+ GSY+C+CN + L++ D C E+N C C N + C C PG+ DS +DI+EC+ + G CIG CR+ + Y+C C P + + D K+C
Sbjct: 204 NGGCGQVCLNT-PNGRICSCHHGYTLEFDEESCRGNTKGRTATGCFFVKFTIQPNKRIHISSTTNVNISDKKSQYVDECQNNNGGCRDLCINTPGSFMCQCRQGYVLANDNKTCIN-LNECATRKHRCEQLCRDTDGGYYCECHKGYQVGPDGMSC-IDVNECLLPKSFHHCDHSCVNTPGSYYCTCNEGFVLSANGRRCRDVN---ECMMGGVKCDQKCVNTPGSYRCECYRGFRQSDDVLKKCIDIDECLEGLPDCHKCTNTAGSYYCTCDTGYKQVNNRTRCQDIDECMDNNGGCGQLCVNTAGSYHCKCEPGYNATDAGARTCVDIDECAGHFGKGDCDHKCNNTAGSFKCSCHHGYALTDDGLTCQDID-ECAVDNGGCHQKCVNSPGNFSCACHDGYITAGRNGSDFICDDIDECASGIHQCEEGATCVNTPGNYSCLCPQGYRSDWNKCVDIDECKQ--RMCEKECVNTEGSYFCFCPPGYQLTDDKRHCQDVDECTAGDVCDQTCINTNGSYYCECKTGF--ELLGDRKTCRDLDECALNTACCNQACVNTEGSYNCTCNSGYELTSRCTCTDIDECAERNGGCQQVCTNTAG--SYSCSCSPGFLIDSRYPKQCKDIDECKTVTAYIGVSCIGVCRSVYRLYQCTCHPKFKLKPDGKSC 858 HSP 2 Score: 168.703 bits (426), Expect = 1.053e-42 Identity = 186/618 (30.10%), Postives = 266/618 (43.04%), Query Frame = 1
Query: 1351 CQQICVNTIGSYQCSCREGFTLL---------SNGKCAINCL-----NNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHG-CEHLCVNVPGSFNCQCHSGFTLQINKKKCIS--------KSCNIEC--LNGGLCDKDKCKCPPGYI----GHNCEFNDFCHF---ISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKL-EC--------PKCVRGTCNENKCKCPKGFAG----LLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQ-CFNSK----CICKSGY----RGKRCDEDINECKKY--SHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCL-EKNDSCSS---PCKNGGKCVNS----KCKCKPGYNGDSCE-EDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVL 3009
C Q+C+NT CSC G+TL + G+ A C NK + S + S +DEC+ N+G C LC+N PGSF CQC G+ L + K CI+ C C +GG C+C GY G +C + C C+H+C + C+C G+ L + + C+ + EC KCV T +C+C +GF L DI+ECL H CTNT GS++C C G+K ++ C ++ C+D + GQ C N+ C C+ GY G R DI+EC + C+H C NT GS+KCSC G+ L+ + +CQ DIDEC ++ C CVNS G++SC+C+ + + +G + + D C+S C+ G CVN+ C C GY D + DI+EC+ + C EC NT G+Y C CPPGY + DD++ CQ DVDEC CD+ C NT GS+YC+C + + L+ D +C + E L
Sbjct: 207 CGQVCLNTPNGRICSCHHGYTLEFDEESCRGNTKGRTATGCFFVKFTIQPNKRIHISSTTNVNIS----DKKSQYVDECQNNNGGCRDLCINTPGSFMCQCRQGYVLANDNKTCINLNECATRKHRCEQLCRDTDGGY----YCECHKGYQVGPDGMSCIDVNECLLPKSFHHCDHSCVNTPGSYYCTCNEGFVLSANGRRCRDVNECMMGGVKCDQKCVN-TPGSYRCECYRGFRQSDDVLKKCIDIDECLEGLPDCHKCTNTAGSYYCTCDTGYKQVNNRTRCQDIDE--CMDNNGGCGQLCVNTAGSYHCKCEPGYNATDAGARTCVDIDECAGHFGKGDCDHKCNNTAGSFKCSCHHGYALTDDGLTCQ------------------------------DIDECAVDNGGCHQKCVNSPGNFSCACHDGYITAGRNGSDFICDDIDECASGIHQCEEGATCVNTPGNYSCLCPQGYRSDWNKCVDIDECKQRM----CEKECVNTEGSYFCFCPPGYQLTDDKRHCQ-------------------------------------DVDECTAGDVCDQ---TCINTNGSYYCECKTGFELLGDRKTCRDLDECAL 739 HSP 3 Score: 84.7297 bits (208), Expect = 1.080e-16 Identity = 96/352 (27.27%), Postives = 152/352 (43.18%), Query Frame = 1
Query: 2035 NGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRG---KRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDF-------NNKCKCKTGWTGELCDVD---IDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSK----CKCKPGY----NGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTM----CNPHCLNGGVCRDMSRCYCPIGFHGIDCG----VDVDECQRYAP-CDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
+G +L + S +PP +++ ++ V + + I K+G+R N C + C C+NT CSC G+ L + SC+ C F N + + + D +DEC N C+ C+N+ GS+ C C + L+ D ++C+ N+ + + C ++ C+C GY +G SC D+NEC P S H C C NT G+Y C C G+++ + + C+ + M C+ C+N RC C GF D +D+DEC P C K C NT GS+YC C + Y + + T C + E
Sbjct: 147 SGQRLGKYCGSSLPPLQRSSSNQMLV--RFVADQSISKTGFRATFRAELQATGNPCITNNGGCGQVCLNTPNGRICSCHHGYTLEFDEESCRGNTKGRTATGCFFVKFTIQPNKRIHISSTTNVNISDKKSQYVDECQNNNGGCRDLCINTPGSFMCQCRQGYVLAN-DNKTCINLNECATRKHRCEQLCRDTDGGYYCECHKGYQVGPDGMSC-IDVNECLLPKSFHHCDHSCVNTPGSYYCTCNEGFVLSANGRRCRDVNECMMGGVKCDQKCVN---TPGSYRCECYRGFRQSDDVLKKCIDIDECLEGLPDCHK----CTNTAGSYYCTCDTGYKQVNNRTRCQDIDE 487 HSP 4 Score: 73.559 bits (179), Expect = 3.068e-13 Identity = 93/336 (27.68%), Postives = 137/336 (40.77%), Query Frame = 1
Query: 1012 CSKGCQNGGTCFQGRCQCTEGF----EGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL-----------DNDGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCN-DDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDC------LNGICYC-----FSGWHGEDCSLDIDECKYNHG-CEHLCVNVPGSFNCQCHSGFTLQ-----INKKKCISKSCNIECLNGGLCDKDKCKCPPGYI-----GHNCEFNDFCHFISP-----CEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKC 1884
C C N F +C C G+ +G CQ +I+ C+ + N C CVN NF C C G+ D D + +C + T GN C C QG++ + D+DEC +C++ CVNT GSY C C G+ L + + + ++ C C NG YC F D+DEC N C CVN GS+NC C+SG+ L + +C ++ + + C C PG++ C+ D C ++ C C ++ C+C P + L PD K+C CP C
Sbjct: 539 CDHKCNNTAGSF--KCSCHHGYALTDDGLTCQ-DIDECA---VDNGGCHQKCVNS-PGNFSCACHDGYITAGRNGSDFICDDIDECASGIHQCEEGATCVNTPGNYSCLCPQGYRSDWNKCVDIDECKQRMCEKECVNTEGSYFCFCPPGYQLTDDKRHCQD-VDECTAGDVCDQTCINTNGSYYCECKTGFELLGDRKTCRDLDECALNTACCNQACVNTEGSYNCTCNSGYELTSRCTCTDIDECAERNGGCQQVCTNTAGSYSCSCSPGFLIDSRYPKQCKDIDECKTVTAYIGVSCIGVCRSVYRLYQCTCHPKFKLKPDGKSCG--HCPTC 864
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO29720 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2U3]) HSP 1 Score: 167.933 bits (424), Expect = 1.272e-43 Identity = 187/616 (30.36%), Postives = 267/616 (43.34%), Query Frame = 1
Query: 1324 DVDECLFPVCQQ--ICVNTIGSYQCSCREGFT-----LLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAE-----DKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILS---ANSHSCQSVCSLCKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC-MTMKEAVLKPHL 3021
++DEC CQ C + + SY C+C G+T ++ + + C+N D C+C G+ G++C +IDEC + C++ C + F C C GFT + +C SK C NG C C C PG+ G +C PC++ CT + C+C PG+ D + C C TC + +C C GF G C +I+EC N CT+ I F C CK G ++ D+ + P N TC D+ ++G C CK G+ GK C +I+EC C + + C+C PGF S C S S CKNG + C CK G+TG C +IDEC K C + ++C+C F G+ C + D C+S PCKNG C + C CK GY G C DI+EC S + C+ G C + Y C+C GY + C++ + +P C NGG C D+ RC+C G+ G C D+DEC +PC G C + + CQCS+ Y G +C + + E KP L
Sbjct: 1 EIDECSSNPCQNGGTCTDQLNSYSCTCPSGYTGTKCEIVPDQCASAPCINGGTCKSDRYGYHCHCKVGFTGKNCETNIDECNSSP-CKNGGSCTDRINRFTCTCKHGFTGKDCGTEIDECASKPCK----NGATCTDRINGFTCTCKPGFTGKDCGTEIDECASKPCKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASKPCKN--GATCTDRINGFRCTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGSDCGTEIDECASSPCKNGATCTDR--ING----FACTCKLGFTGKDCGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGSDCGTEIDECAS--SPCKNGATCTDRINGFACTCKPGFTGSDCGTEIDECASKPCKNGATCTDRINGFACTCKPGFT-----GKDCGTEIDECASEPCKNGANCTDKINGFMCTCKEGYTGKDCGTDIDEC----SSNPCLNEGTCTDQVNGYLCVCKKGYTGPN----CEVEVNECQSDP-CQNGGTCEDLIASYRCFCKAGYTGRHCETDIDECAS-SPCAN-GGTCTDLVDAHKCQCSTGYT----GKNCEVNIDECATKPCL 581 HSP 2 Score: 160.229 bits (404), Expect = 4.673e-41 Identity = 194/669 (29.00%), Postives = 274/669 (40.96%), Query Frame = 1
Query: 1000 ELRTCSKG-CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG----DCLNG-ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSL-CKNGKCDFNN----KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQ 2877
E+ CS CQNGGTC C C G+ G +C++ + C+ C+N G C+S ++G +C CK G+ GK C ++DEC C+ C + I + C+C+ GFT G C + KNG D +NG C C G+ G+DC +IDEC C++ C + F C C GFT + +C SK C NG C +C C PG+ G +C +PC++ CT + C+C PG+ D + C C TC + C C GF G C +I+EC + CKNG TC D+ ++G C CK G+ G C +I+EC C + + C+C PGF S S CKNG + C CK G+TG+ C +IDEC K NC + + C+C + G+ C D CSS PC N G C + C CK GY G +CE ++NECQ ++G G C + +Y C C GY + C+ + +P C NGG C D+ +C C G+ G +C V++DEC
Sbjct: 1 EIDECSSNPCQNGGTCTDQLNSYSCTCPSGYTGTKCEIVPDQCASAP---------CINGG------TCKS----------------DRYGY------HCHCKVGFTGKNCETNIDECNSSPCKNGGSCTDRINRFTCTCKHGFTGKDCGTEIDECASKPCKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASKP-CKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASKPCK----NGATCTDRINGFRCTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGSDCGTEIDECASSPCKN--GATCTDRINGFACTCKLGFTGKDCGTEIDECASN----------------PCKNGA---------------TCTDR--ING----FTCTCKPGFTGSDCGTEIDECASSPCKNGATCTDRINGFACTCKPGFTGSDCGTEIDECASKPCKNGATCTDRINGFACTCKPGFTGKDCGTEIDECASEPCKNGANCTDKINGFMCTCKEGYT-----GKDCGTDIDECSSNPCLNEGTCTDQVNGYLCVCKKGYTGPNCEVEVNECQSDPCQNG--GTCEDLIASYRCFCKAGYT----GRHCETDIDECASSP-CANGGTCTDLVDAHKCQCSTGYTGKNCEVNIDECA 576 HSP 3 Score: 158.688 bits (400), Expect = 1.402e-40 Identity = 175/587 (29.81%), Postives = 256/587 (43.61%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKS---CIKEECSKFGT-TEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNG----DCLNG-ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGY---DLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHV-CTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI---LSANSHSCQSVCSLCKNGKCDFN----NKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSC 2472
C C +G+ G +C I+ P+ C C++G + + + C C + T NC + C S C+NGG+C + C C GF G C EI+ C+ N C + N F C C+ GF + G C + C T T+ ++G C CK G+ GK C ++DEC C+ C + I ++C+C+ GFT G C +N KNG D +NG C C G+ G DC +IDEC + C++ C + F C C GFT + + I + + C NG C C C PG+ G +C SPC++ CT + C+C PG+ D + C C TC + C C GF G C +I+EC ++ CT+ I F C CK G+ + + CL++ Q C+CK GY G C+ ++NEC+ C + SY+C C G+ + C S S C NG + +KC+C TG+TG+ C+V+IDEC CV+ Y C C
Sbjct: 25 CTCPSGYTGTKCEIV-PDQCASAP---CINGGTCKSDRYGYHCHCKVGFTGKNCETNIDECNSSPCKNGGSCTDRINRFTCTCKHGFTGKDCGTEIDECASKPCKNG---ATCTDR-INGFTCTCKPGFTGKDCGTEIDECASKPCKNGATCTDRINGFTCTCKPGFTGKDCGTEIDECASKPCKNGATCTDRINGFRCTCKPGFTGKDCGTEIDECASNPCKNGATCTDRINGFTCTCKPGFTGSDCGTEIDECASSP-CKNGATCTDRINGFACTCKLGFTGKDCGTE-IDECASNPCKNGATCTDRINGFTCTCKPGFTGSDCGTEIDECASSPCKNGATCTDRINGFACTCKPGFTGSDCGTEIDECASKPCKN--GATCTDRINGFACTCKPGFTGKDCGTEIDECASEPCKNGANCTDKINGFMCTCKEGYTGKDCGTDIDECSSNPCLNEGTCTDQVNGYLCVCKKGYTGPNCEVEVNECQSDPCQNGGTCEDLIASYRCFCKAGYTGRHCETDIDECAS--SPCANGGTCTDLVDAHKCQCSTGYTGKNCEVNIDECATKPCLNGATCVDQIAVYKCLC 597
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Match: notch1a (neurogenic locus notch homolog protein 1 [Source:NCBI gene;Acc:101171596]) HSP 1 Score: 211.846 bits (538), Expect = 2.339e-55 Identity = 236/821 (28.75%), Postives = 345/821 (42.02%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTC------FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAIN----CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH-LCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFN-DFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCV------RGTC----NENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNG--------HKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCK-----------CKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD-----------------------------TMC--------NPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
C C GW G+ C + C HG + R F C C T C L+ S CQ G C + C C G+ G C L+I+ C+ +G CEH C+N +FQCKC G++ + D C+ C T ++ +C C G++G FC+ D DEC C C++ I S+ C C +GF S C ++ C C +G C C G+ G+ C +DI+EC Y+ C + C + SF C C G+T ++ N +C+S+ C NGG C + C CP G G NCE N D C PC++ C + C+C PGY T + C GTC N C CP+G+ C + ++EC + +C + I + C C +G +K D C+ N TC KD G C C+ G+ G C +INEC + + C++ YKC+C+ L +C+++ + C + C CK C GW G+ C++DI+EC+ + C+N+ G Y C C F G+ C D C +PC NGG C + C C PG+ G CE+DINEC+ K+G C + +Y C CP G+ ++ C+I+T D + C + CLNGG C D +C CP G+ G++C V C +PC K G C+ S+ CQC + + +Y
Sbjct: 320 HCVCVNGWTGDDCS----KNIDDCAAAACFHGATCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPPGYTGSACNLDIDECA---LGANPCEHGGRCLNT-LGSFQCKCLQGYEGPRCEMDVNECMSNPCQNDATCLDQIGGFHCICMPGYEGVFCHIDTDECASQPCLNNGKCIDKINSFYCECPKGF---SGNLCQVDIDECASTPCRNGAKCTDGPNKYNCECAEGYTGQHCEIDINEC-YSDPCHYGTCKDGLASFTCYCRPGYTGRLCETNINECLSQPCK----NGGTCQDRENSYICSCPKGTAGFNCEINLDDCKS-QPCDYGRCIDKINGYECACRPGY-----TGTMCNINIDDCAINPCHNGGTCIDGINSFTCLCPEGYNDATCLSQVDECSSNPCIHGLCQDLINGYKCTCDSGWSGQNCDINKNECDSNPCM--NGGTC--KDMTSGY----HCTCRVGFTGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCL----LPYTGENCETLLAPCSSRPCKNGGVCKEAEDYQSFSCICPEGWQGQTCEIDINECVKSPCWNGAFCLNTMGGYQCKCQPGFT-----GQKCETDIDDCKPNPCSNGGLCHDGISSFTCTCLPGFRGGRCEQDINECESNPCKNG--ANCTDCVNSYTCTCPTGFSGIN----CEINTNDCTDSSCFNGGTCVDGINSFTCLCLTGFTGSYCQFDINECDSKPCLNGGTCLDGYGTYKCTCPHGYTGVNCQHLVRWCDS-SPC-KNGGTCWQQGASYTCQCQTGWTGLY 1093 HSP 2 Score: 199.519 bits (506), Expect = 1.574e-51 Identity = 241/823 (29.28%), Postives = 347/823 (42.16%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAIN----CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKD-----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVR-----GTCNENK------CKCPKGFAGLLCENDINECLNQTICQHV-CTNTIGSFFCRCK---NGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSC-QSVC---SLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC----------------------------VNSK------------------------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRY------APCDKLRGICYNTYGSFYCQCSSNYV 2961
C C G+ G C I E Q L +G DK F C C + N C +++ C S C+NG C G C+C EG+ G C+++IN C + C + +G +F C C+ G+ + + C+ + C GT + + C C +G G C ++D+C C C++ I Y+C+CR G+T C IN +N C+ G C++GI C C G++ C +DEC N LC ++ + C C SG++ Q INK +C S C +NGG C KD C C G+ G NC+ N +PC + T I+D C+CL Y + C+ L P R G C E + C CP+G+ G CE DINEC+ C NT+G + C+C+ G K D C P C + H + C C G+RG RC++DINEC+ C + SY C+C GF N++ C S C C +G F C C TG+TG C DI+EC C++ G+Y C+C P + V+ + + DS SPCKNGG C V +K C+C+ GY G C+E ++EC ++G C + G Y C C PGY ++ C + P C NGG C D+ +C CP G G+ C +++D+C + P G C + G + C C YV
Sbjct: 475 HCICMPGYEGVFCHIDTDECASQPCL---NNGKCIDKIN-SFYCECPKGFSGNLCQVDIDECASTPCRNGAKCTDGPNKYNCECAEGYTGQHCEIDINECY-----SDPCHYGTCKDGLASFTCYCRPGYTGRLCETNINECLSQPCKNGGTCQDRENSYICSCPKGTAGFNCEINLDDCKSQPCDYGRCIDKINGYECACRPGYT---GTMCNINIDDCAINPCHNGGTCIDGINSFTCLCPEGYNDATCLSQVDECSSNPCIHGLCQDLINGYKCTCDSGWSGQNCDINKNECDSNPC----MNGGTC-KDMTSGYHCTCRVGFTGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYT----GENCETLLAPCSSRPCKNGGVCKEAEDYQSFSCICPEGWQGQTCEIDINECVKSPCWNGAFCLNTMGGYQCKCQPGFTGQKCETDIDDCKP---NPCSNGGLCHDGISSFTCTCLPGFRGGRCEQDINECESNPCKNGANCTDCVNSYTCTCPTGFSGINCEINTNDCTDSSCFNGGTCVDGINSFT--CLCLTGFTGSYCQFDINECDSKPCLNGGTCLDGYGTYKCTC--PHGYTGVNCQHLVRWCDS--SPCKNGGTCWQQGASYTCQCQTGWTGLYCDIPSVSCEVAAKQQGVEVNQLCRNSGQCLDAGSTHHCRCQAGYTGSYCQEQVDECSPNPCQNG--ATCTDYLGGYSCECVPGYHGVN----CSKEINECQSQP-CQNGGTCIDLINTYKCSCPRGTQGVHCEMNLDDCNPFNDPFTNEPKCFNNGRCVDRIGGYQCMCPPGYV 1260 HSP 3 Score: 197.208 bits (500), Expect = 9.482e-51 Identity = 225/711 (31.65%), Postives = 322/711 (45.29%), Query Frame = 1
Query: 1024 CQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICV-NEGENNFQCKCQSGF-----QLDNDGKSCIKEECSKFGT--TEVVSGN--CKCKQGWKGKFCNDDVDECLFPV--CQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK----YNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEH-NCTTINDNMVCSCLPGYD-LMPDKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHK-----LAEDKRSCIP-PNKKTCLDKDCVHGQCFNS-KCICKSGYRGKRCDEDINECKKYSHICEH-FCMNTEGSYKCSCMPGFILS---ANSHSCQSVCSLCKNGKC--DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
CQNGGTC C C G+ GD C I+ C+ C H ++ +F C+C G LD+ +CI C K T V+G C C G+ G CN D+DEC C+ C+NT+GS+QC C +G+ +C ++ C++N C + CL+ I C C G+ G C +D DEC N+G C++ SF C+C GF+ Q++ +C S C +C +G +K C+C GY G +CE + + PC + C + C C PGY + + + L P GTC + + C CPKG AG CE ++++C +Q C + I + C C+ G+ + D + P N TC+D NS C+C GY C ++EC S+ C H C + YKC+C G+ N + C S + C NG D + C C+ G+TG C +I+EC N Q C++ Y C+C LP+ G +C CSS PCKNGG C ++ C C G+ G +CE DINEC +G C NT G Y+C C PG+ + C+ D NP C NGG+C D C C GF G C D++EC+ PC K C + S+ C C + +
Sbjct: 306 CQNGGTCHDTHGSYHCVCVNGWTGDDCSKNIDDCAAA-----ACFHGATCHDRVASFFCECPHGRTGLLCHLDD---ACISNPCQKGSNCDTNPVNGKAICTCPPGYTGSACNLDIDECALGANPCEHGGRCLNTLGSFQCKCLQGY---EGPRCEMDVNECMSNPCQNDATCLDQIGGFHCICMPGYEGVFCHIDTDECASQPCLNNG---KCIDKINSFYCECPKGFSGNLCQVDIDECASTPCRNGAKCTDGP--NKYNCECAEGYTGQHCEIDINECYSDPCHYGTCKDGLASFTCYCRPGYTGRLCETNINECLSQPCKNGGTCQDRENSYICSCPKGTAGFNCEINLDDCKSQPCDYGRCIDKINGYECACRPGYTGTMCNINIDDCAINPCHNGGTCIDG-------INSFTCLCPEGYNDATCLSQVDECS--SNPCIHGLCQDLINGYKCTCDSGWSGQNCDINKNECDS--NPCMNGGTCKDMTSGYHCTCRVGFTGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY-----TGENCETLLAPCSSRPCKNGGVCKEAEDYQSFSCICPEGWQGQTCEIDINECVKSPCWNGAF--CLNTMGGYQCKCQPGFT----GQKCETDIDDCKPNP-CSNGGLCHDGISSFTCTCLPGFRGGRCEQDINECES-NPC-KNGANCTDCVNSYTCTCPTGF 975 HSP 4 Score: 187.963 bits (476), Expect = 7.912e-48 Identity = 224/748 (29.95%), Postives = 326/748 (43.58%), Query Frame = 1
Query: 952 DFSCICGIKETQNNCLELRTC-SKGCQNGGTCFQ----GRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQ---SGFQLDNDGKSCIKEECSKFGT---TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINC---LNNCNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQI--NKKKCISKSCN--IECLNGGLCDKDKCKCPPGYIGHNCEFN-DFCHF-ISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENK----------CKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGH-----KLAEDKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH-FCMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKC--DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHN-CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI-GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTM 2994
DF C C T +C C S C NGG C RC C F G C+L++N C++ C + ICVNE ++ C+C +G C C GT + +C C G+ G+ C ++D+C CQ +C + + +Y C C +T + C N C G C + C C +GW G+DCS +ID+C C H C + SF C+C G T + CIS C C + K C CPPGY G C + D C +PCEH C + C CL GY + C +++ +C+ C + C C G+ G+ C D +EC +Q + C + I SF+C C G ++ D+ + P N C D + C C GY G+ C+ DINEC YS C + C + S+ C C PG+ + N + C S CKNG D N C C G G C++++D+C C + C++ Y C+C P Y T+ C D C+ +PC NGG C++ C C GYN +C ++EC S + CI G C++ Y+C C G+ + C I+ + NP C+NGG C+DM+ C C +GF G +C +++EC PC +G C + + C C +L Y G +C T+
Sbjct: 124 DFRCQCPPGWTGKSCQTPNPCASNPCANGGQCSSLDSTYRCTCPPNFHGQTCKLDVNECAQTPY---LCLNGGICVNE-VGSYHCRCPQEYTGQHCQTPYVPCSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHCEHNIDDCPGHNCQNGGVCADGVNTYNCQCPPHYTGQYCTENVDECEMMPNVCQNGGTCHDTHGSYHCVCVNGWTGDDCSKNIDDCAA-AACFHGATCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPPGYTGSACNLDIDECALGANPCEHGGRCLNTLGSFQCKCLQGY----EGPRC-EMDVNECMSNPCQNDATCLDQIGGFHCICMPGYEGVFCHIDTDECASQPCLNNGKCIDKINSFYCECPKGFSGNLCQVDIDECASTPCRNGAKCTDGPNKY------NCECAEGYTGQHCEIDINEC--YSDPCHYGTCKDGLASFTCYCRPGYTGRLCETNINECLS--QPCKNGGTCQDRENSYICSCPKGTAGFNCEINLDDC--KSQPCDYGRCIDKINGYECACR-PGYTGTM----CNINIDDCAINPCHNGGTCIDGINSFTCLCPEGYNDATCLSQVDEC----SSNPCIHGLCQDLINGYKCTCDSGW----SGQNCDINKNECDSNP-CMNGGTCKDMTSGYHCTCRVGFTGPNCQTNINECAS-NPCLN-QGTCIDDVAGYKCNC----LLPYTGENCETL 829 HSP 5 Score: 163.696 bits (413), Expect = 2.683e-40 Identity = 226/792 (28.54%), Postives = 326/792 (41.16%), Query Frame = 1
Query: 754 EVVCLNKPAIDNCVPDCGEHGICVK----SRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICV---NEGENNFQCKCQSGFQLDN---DGKSCIKEEC--SKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNNCNKNG----DCLNG-ICYCFSGWHGEDCSLDIDECK----YNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQHV-----------CTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSC---MPGFILSANSHSCQSVCSLCKNGKCDFNN----------KCKCKTGWTGELCDVDIDECLLN--QHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNSK-------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMC--NPHCLNGGVCRDMS-----RCYCPIGFHGIDCGV 2859
+ CL++ +D C + HG+C +C C++GW G+ C I + E C C++G + + C C + T NC + C S C N GTC +C C + G+ C+ + CS +R C++ V E +F C C G+Q D C+K C F + CKC+ G+ G+ C D+D+C C +C + I S+ C+C GF G+C + C +N KNG DC+N C C +G+ G +C ++ ++C +N G CV+ SF C C +GFT Q + +C SK C LNGG C KC CP GY G NC+ H + C D CK GTC + C+C G+ GL C+ C Q V C + + CRC+ G+ + E C P N TC D C C GY G C ++INEC+ C++ +YKCSC G N C N FNN +C C G+ GE C+ D++ECL + + +NC+ SY C C + G+ C + D C PC+NGG C + CKC PG+ G SCE D + C K+G G C + C+CP + + C+ T D++C NP C NGG C+ +C CP F+G+ C +
Sbjct: 710 DATCLSQ--VDECSSNPCIHGLCQDLINGYKCTCDSGWSGQNCDINKNE-CDSNP---CMNGGTCKDMTSGYHCTCRVGFTGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGENCETLLAPCS-----SRPCKNGGVCKEAEDYQSFSCICPEGWQGQTCEIDINECVKSPCWNGAFCLNTMGGYQCKCQPGFTGQKCETDIDDCKPNPCSNGGLCHDGISSFTCTCLPGF---RGGRCEQDINECESNPCKNGANCTDCVNSYTCTCPTGFSGINCEINTNDCTDSSCFNGG---TCVDGINSFTCLCLTGFTGSYCQFDINECDSKPC----LNGGTCLDGYGTYKCTCPHGYTGVNCQ-----HLVRWC-----------------------DSSPCKN-------GGTCWQQGASYTCQCQTGWTGLYCDIPSVSCEVAAKQQGVEVNQLCRNSGQCLDAGSTHHCRCQAGYTGSYCQEQVDECSPNPCQNGATCTDY------LGGYSCECVPGYHGVNCSKEINECQSQPCQNGGTCIDLINTYKCSCPRGTQGVHCEMNLDDCNPFNDPFTNEPKCFNNGRCVDRIGGYQCMCPPGYVGERCEGDVNECLSDPCDPRGSYNCIQLMNSYRCECRTGYT-----GQRCDKVFDGCKGRPCRNGGTCAVASNTPHGFICKCPPGFTGSSCEYDSHSCGSLNCKNG--GTCVSGHLGPRCLCPSAFTGPE----CETPT-DSLCISNP-CYNGGTCQTTPNAPFFKCSCPSNFNGLLCHI 1426 HSP 6 Score: 155.221 bits (391), Expect = 1.126e-37 Identity = 210/772 (27.20%), Postives = 298/772 (38.60%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEP---ELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRT---CSKGCQNGGTC-----FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQSGFQLDNDGKSCIKE--ECSKFG---------TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNT-IGSYQCSCREGFTLLSNGKCAINCL-NNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKY-NHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCE--HNCTT--INDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCY---CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C C + + G RC P C+ V DF C C + T CL S C+NGGTC RCQC G+ G CQ N C+ + C N G+ + ++C C F G++C + EC++ EV S +C+C Q + G+ C C CQ CV +Y CSC GF +C +NC G C +G+ C C + G+ C+ ++DEC+ + C++ C + GS++C C +G+T + K I C +G C C+CP G G C +D C +PC+ NC T +N +C+C P G+ G C DI+EC L C+H C NT+GSF C+C GY G RC+ D+NEC + C++ G + C CMPG+ ++ C S L NGKC D N C+C G++G LC VDIDEC S+PC+NG KC + C+C GY G CE DINEC S G C++ ++ C C PGY + C+ + + + P C NGG C+D Y CP G G +C +++D+C + PCD G C + + C C Y
Sbjct: 45 ECRCPSDYIGNRCQYPSPCSPSPCRNGGRCRAVS----RGNTFDFLCECPLGFTDRLCLTPTNHACMSAPCRNGGTCELIALTDFRCQCPPGWTGKSCQTP-NPCA---------SNPCANGGQCSSLDSTYRCTCPPNFH----GQTCKLDVNECAQTPYLCLNGGICVNEVGSYHCRCPQEYTGQHCQTPYVPCSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHCEHNIDDCPGHNCQNGGVCADGVNTYNCQCPPHYTGQYCTENVDECEMMPNVCQNGGTCHDTHGSYHCVCVNGWTGD-DCSKNIDDCAAAACFHGATCHDRVASFFCECPHGRTGLLCHLDDAC-ISNPCQKGSNCDTNPVNGKAICTC---------------------------------PPGYTGSACNLDIDECALGANPCEHGGRCLNTLGSFQCKCLQ--------------------------------------GYEGPRCEMDVNECMSNPCQNDATCLDQIGGFHCICMPGYEGVFCHIDTDECASQPCL-NNGKCIDKINSFYCECPKGFSGNLCQVDIDECA------------------------------------------STPCRNGAKCTDGPNKYNCECAEGYTGQHCEIDINEC---YSDPCHYGTCKDGLASFTCYCRPGYT----GRLCETNINECLSQP-CKNGGTCQDRENSYICSCPKGTAGFNCEINLDDC-KSQPCD--YGRCIDKINGYECACRPGYT 671 HSP 7 Score: 124.79 bits (312), Expect = 2.847e-28 Identity = 143/489 (29.24%), Postives = 209/489 (42.74%), Query Frame = 1
Query: 1672 CLNGGLC-----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINE------CLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHG-QCFN----SKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQS-----VCSLCKNG-----KCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS---SPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVL----DDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYA-PCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC-MTMKEAVLKP 3015
CLNGG C +C+CP YIG+ C++ C SPC + C RG + C+CP GF LC N C N C+ + + F C+C G +SC PN C C +G QC + +C C + G+ C D+NEC + ++C + C+N GSY C C + CQ+ S C+NG K D C C G+ G+ C+ +ID+C H CQ+ V ++G + +C P + + G+ C E D C + C+NGG C ++ C C G+ GD C ++I++C HG C + ++ C CP G L DD K + C+ + +NG + C CP G+ G C +D+DEC A PC+ G C NT GSF C+C + Y+G C M + E + P
Sbjct: 30 CLNGGRCVATSSGNGECRCPSDYIGNRCQYPSPCS-PSPCRNG---------------------------GRCRAVSRGNTFDFLCECPLGFTDRLCLTPTNHACMSAPCRNGGTCELI---ALTDFRCQCPPGWT----GKSCQTPNP--CASNPCANGGQCSSLDSTYRCTCPPNFHGQTCKLDVNECAQTPYLCLNGGICVNEVGSYHCRCPQEYT----GQHCQTPYVPCSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHCEHNIDDCP--GHNCQNGGVCADGVNTYNCQCPPHYT---GQYCTENVDECEMMPNVCQNGGTCHDTHGSYHCVCVNGWTGDDCSKNIDDCAAAACFHG--ATCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNG-----KAICTCPPGYTGSACNLDIDECALGANPCEH-GGRCLNTLGSFQCKC----LQGYEGPRCEMDVNECMSNP 460
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:101162450]) HSP 1 Score: 206.453 bits (524), Expect = 1.189e-53 Identity = 233/807 (28.87%), Postives = 338/807 (41.88%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTC----FQGR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT----LLSNGKCAINCLNNCNKNGDCLNGI-CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL-----QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCV---RGTCNENK----CKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE---DKRSCIPP---NKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCD-----------FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC---VNS-KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD------------------------------------TMCNPH-CLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
C C GW G+ C E C +G + R F C C + +T C L+ S C G C GR C C GF G C +++ CS +G CEH CVN E +FQC+C G+ + + D C+ C T + C C G+ G +C D+D+C C +C +T+ + C+C+ GF+ + +CA N K D NG C C G+ G C +I+ C+ + C++ S+ C C G+T Q+N+ C S C L +K C+C G G NCE N +PC++ C + C C PG+ K + EC GTC + + C CP+GF C + ++EC + C I + C C+ G D+ C+P N TC+DK ++G C C+ G+ G C +INEC + + C++ S+ C C L + +C V + C C +C C+ GW G+LC++D++EC+ N K + C N+ G + CSC F T + + ND +PC +GG C VNS C C PG+ G C +INECQ K+G G C + +Y C C PG+ + C+I+ D CN CLNGGVC+D RC CP G+ G C VD C+R +PC G C SF C+C + + Y
Sbjct: 247 CVCVNGWTGDDCS----ENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECS---IGANPCEHFGKCVNT-EGSFQCQCGRGYAGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTYCQTDIDDCESNPCVNDGVCRDTVNGFTCTCQPGFSGTMCQIDIDECASTPCQNGAKCHDRPNGFECRCAEGYEGTLCESNINNCQPDPCHHGTCIDGIASYTCNCDPGYTGYRCENQLNE--CHSNPCQNSGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYDCVCKPGF--TGPKCNVEIDECASSPCRNGGTCVDEENGFHCLCPEGFKPPYCYSQVDECGSSPCVHGSCREDINGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDK--LNG----FTCKCRQGFIGNLCQVNINECASNPCLNKGTCVDGVASFTCVCE----LPYSGPTCAEVLTPCSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECISNPCKNRGTCTNTLGGFVCSCRAGFTGLTCE----TDINDCVPNPCLSGGSCTDGVNSYHCSCLPGFTGSRCALEINECQSNPCKNG--GTCTDYVNSYTCTCRPGFTGIH----CEINIPDCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYTGNRCQTPVDWCRRSSPCQN-GGRCRQNDASFTCECKNGWSGHY 1020 HSP 2 Score: 189.504 bits (480), Expect = 2.701e-48 Identity = 225/784 (28.70%), Postives = 324/784 (41.33%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFC-VHGCSFDKRKLD----FSCICGIKETQNNC-LELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-------QLDNDGKS-CIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN-----GDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH-LCVNVPG--SFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCK-------NGKCDFNNK---CKCKTGWTGELCDVDIDEC--------LLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCV----NSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVL---DDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDEC 2874
I+NC PD HG C+ C C+ G+ G RC + +L C + C + +D + C C + NC + C+ + G C G C C GF G +C +EI+ C+ N CV+E EN F C C GF Q+D G S C+ C + ++ C C+ GW GK C+ D ++CL CQ C++ + + C CR+GF C +N +N C N G C++G+ C C + G C+ + C N H +C + + C C G+ Q I+ +CIS C N G C C C G+ G CE T IND + CL G C G N C C GF G C +INEC + C++ CT+ + S+ C C+ G + + IP DC CFN C C+SG+ G C ++NEC + C + S++C+C G+ + CQ+ C+ G+C N+ C+CK GW+G CD+ C + C H +CVN+ ++ C C + G C + D C PC+NG C +C C PG+ G +CE +INECQ ++G G C + G+Y C CPPG L + ++ C + P CLN G C D RC CP GF G C D++EC
Sbjct: 493 INNCQPDPCHHGTCIDGIASYTCNCDPGYTGYRC---------ENQLNECHSNPCQNSGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYDCVCKPGFTGPKCNVEIDECASSPCRNGG---TCVDE-ENGFHCLCPEGFKPPYCYSQVDECGSSPCVHGSCRE----DINGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQGFI---GNLCQVN-INECASNPCLNKGTCVDGVASFTCVCELPYSGPTCAEVLTPCSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECISNPCK----NRGTCTNTLGGFVCSCRAGFTGLTCE---------------TDINDCVPNPCLSGG---------------SCTDGV-NSYHCSCLPGFTGSRCALEINECQSNP-CKNGGTCTDYVNSYTCTCRPGFTGIHCEIN-IP---------DCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYT----GNRCQTPVDWCRRSSPCQNGGRCRQNDASFTCECKNGWSGHYCDIPRVSCETAARQRGIQTDELCHHGGHCVNTGNTHFCKCPADYT-----GSYCESQVDHCEDKPCRNGATCRPYVGGYQCDCMPGFMGQNCEREINECQSHPCQNG--GTCIDLVGHYICSCPPGTLGVLCEINEDDCNTPVRPRNAPPKCLNNGTCVDRVGGYRCNCPPGFTGERCEGDINEC 1198 HSP 3 Score: 185.267 bits (469), Expect = 5.660e-47 Identity = 226/815 (27.73%), Postives = 327/815 (40.12%), Query Frame = 1
Query: 1024 CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDECLFP--VCQQ--ICVNTIGSYQCSCREGFT-------------------------------LLSNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN-------CTTINDNMVCSCLPGYDLMP---DKKTCKKLECPKCVR--GTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGH-------KLAE-------DKRSCI-------------------PPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILS---ANSHSCQSVCSLCKNGKC--DFNN-KCKCKTGWTGELCDVDIDECL-------------------------------LNQHKCQHN-------CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS------KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
C N G C RCQC G+ G C++ C+ Q N C +++++C C GF+ N + C +C G V + NC+C W G++C +DV+ECL C C NTIG + C C G+T GK + C N CN+ C LNG IC C +G+ G C+ D+DEC + CEH CVN GSF CQC G+ +I+ +C+S C + + C C PGY G C+ + I CE N C + C+C PG+ D C C + N +C+C +G+ G LCE++IN C C + I S+ C C G+ +L E + C+ N C C +G C + C+CK G+ G +C+ +I+EC C++ E + C C GF + C S S C +G C D N +C C+ GW G+ CD+D ++CL +N ++C N CV+ S++C C LP+ G +C E CS +PC N C ++ +C C+PG+ G C D+NEC K+ G C NT G + C C G+ L TC+ D + NP CL+GG C D C C GF G C ++++ECQ PC K G C + S+ C C + ++
Sbjct: 115 CLNNGLCINMKGSFRCQCQPGYSGRICEVPTLPCAPSQCLNGG---TCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNGGLCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYAGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTYCQTD-----IDDCESNPCVNDGVCRDTVNGFTCTCQPGFSGTMCQIDIDECASTPCQNGAKCHDRPNGFECRCAEGYEGTLCESNINNCQPDPCHHGTCIDGIASYTCNCDPGYTGYRCENQLNECHSNPCQNSGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYDCVCKPGFTGPKCNVEIDECASSPCRNGGTCVDEENGFHCLCPEGFKPPYCYSQVDECGS--SPCVHGSCREDINGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQGFIGNLCQVNINECASNPCLNKGTCVDGVASFTCVCELPY-----SGPTCAEVLTPCSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECISNPCKN--RGTCTNTLGGFVCSCRAGFTGL----TCETDINDCVPNP-CLSGGSCTDGVNSYHCSCLPGFTGSRCALEINECQS-NPC-KNGGTCTDYVNSYTCTCRPGFTGIH 905 HSP 4 Score: 130.183 bits (326), Expect = 6.280e-30 Identity = 126/414 (30.43%), Postives = 178/414 (43.00%), Query Frame = 1
Query: 1900 NENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLD-KDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMP---GFILSANSHSCQSVCSLCKNGKCDFN----NKCKCKTGWTGELCDVDIDECL----LNQHKCQHNCVNS------------------------------------NGSYSCSCNLPFYLSTVDGRSCLEKNDSCS---SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINEC-QWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
++ C CP GF G C NDINEC +C + +C N GSF C+C+ G+ + +P CL+ C + +C C G+ G C++++++C + + C++ +Y C C P G + + + C + C NG FN + C C GWTG+ C +ID+C N C H+ V S NG C+C F G +C + D CS +PC++ GKCVN+ +C+C GY G CE DINEC P C + G + CIC PGY CQ D NP C+N GVCRD C C GF G C +D+DEC PC C++ F C+C+ Y
Sbjct: 87 DQYNCSCPPGFQGKNCHNDINECRKPGVCLNNGLCINMKGSFRCQCQPGYSGRICEVPTLPCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNGGLCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATC-HDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFV-----GGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYAGPRCEIDINECLSMPCQND---ATCLDRIGEFTCICMPGYT----GTYCQTDIDDCESNP-CVNDGVCRDTVNGFTCTCQPGFSGTMCQIDIDECAS-TPCQN-GAKCHDRPNGFECRCAEGY 484 HSP 5 Score: 111.309 bits (277), Expect = 3.601e-24 Identity = 168/622 (27.01%), Postives = 249/622 (40.03%), Query Frame = 1
Query: 778 AIDNCVPD-CGEHGICVKS------RCYCETGWFGERCVILEPE----LCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNR-TCEHICVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT-TEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG----------ICYCFSGWHGEDCSLDIDEC---------KYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGY-----DLMPD---KKTCKKLECPKCVR-GTCNEN----KCKCPKGFAGLLCENDINECLNQTIC---QHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNK-KTCLDKDCVHGQC--------FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCS--LCKNGKCDFNN------KCKCKTGWTGELCD 2388
+ C P+ C H +C + +C C+ GW G+ C I E CK R G F C C T C ++ C C +GG+C G C C GF G +C LEIN C N TC N++ C C+ GF + + C + C GT T+ ++G +C C+ G+ G C +V+EC C +C + + S++C+C +G+T G ++ C ++ C NG C C +GW G C + C + + C H CVN + C+C + +T + + + + C NG C +C C PG++G NCE PC++ T I+ + +CSC PG ++ D + PKC+ GTC + +C CP GF G CE DINECL+ C + C CK G R C NK C + C +G C C+ GY G C+ ++ C++ S C T +CSC+PG+ H CS C+NG C+C W G+ C+
Sbjct: 755 VLTPCSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECISNPCKNRGTCTNTLG--------GFVCSCRAGFTGLTCETDINDCVPNPCLSGGSCTDGVNSYHCSCLPGFTGSRCALEINECQSNPCKNGGTCTDYV-----NSYTCTCRPGFTGIHCEINIPDCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYT----GNRCQTPVDWCRRSSPCQNGGRCRQNDASFTCECKNGWSGHYCDIPRVSCETAARQRGIQTDELCHHGGHCVNTGNTHFCKCPADYTGSYCESQ-VDHCEDKPCRNGATCRPYVGGYQCDCMPGFMGQNCEREINECQSHPCQNGGTCIDLVGHYICSCPPGTLGVLCEINEDDCNTPVRPRNAPPKCLNNGTCVDRVGGYRCNCPPGFTGERCEGDINECLSNPCSPSNSFDCIQLPNDYQCVCKPGFT----GRRCQ--NKFSVCESQPCQNGGACSVSSSSPLGYTCTCQLGYIGPNCERSMS-CRELSCYNGGSCTLTSRGARCSCLPGYGGPQCQHRSTEGCSSKPCRNGGVCTEETSYPYFSCQCSKDWAGKRCE 1351 HSP 6 Score: 77.7962 bits (190), Expect = 6.134e-14 Identity = 60/171 (35.09%), Postives = 84/171 (49.12%), Query Frame = 1
Query: 2491 STVDGRSCLEKNDSCSSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNP-HCLNGGVCRDMS----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
ST+ + C + +SPC NG +CVN C C PG+ G +C DINEC+ P C+ G C N G++ C C PGY + C++ T C P CLNGG CR S C C GF G +C +VD+C + + G+C + ++ CQC + Y
Sbjct: 58 STLWSQDCSRIDACATSPCANGARCVNWNDQYNCSCPPGFQGKNCHNDINECRKPGV---CLNNGLCINMKGSFRCQCQPGY----SGRICEVPT--LPCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNG--GLCVDGVNTYNCQCPPEWTGQY 217 HSP 7 Score: 70.0922 bits (170), Expect = 1.480e-11 Identity = 68/200 (34.00%), Postives = 90/200 (45.00%), Query Frame = 1
Query: 2395 IDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSP--CKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGN-YECICPPGYLVLDDQKTCQISTKDTMCNPH-CLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
ID C + CVN N Y+CSC F G++C + C P C N G C+N K C+C+PGY+G CE C +G G CR T + YEC C PG+ + C+ + D C H C+NGG+C D C CP + G C DV+EC G C+NT G C C + +
Sbjct: 68 IDACATSPCANGARCVNWNDQYNCSCPPGF-----QGKNCHNDINECRKPGVCLNNGLCINMKGSFRCQCQPGYSGRICEVPTLPCAPSQCLNG--GTCRQTSDHSYECACLPGF----EGHNCEKNVDD--CPGHKCMNGGLCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWT 254
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:101162450]) HSP 1 Score: 206.453 bits (524), Expect = 1.252e-53 Identity = 233/807 (28.87%), Postives = 338/807 (41.88%), Query Frame = 1
Query: 835 CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKGCQNGGTC----FQGR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHI--CVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFT----LLSNGKCAINCLNNCNKNGDCLNGI-CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTL-----QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN-CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCV---RGTCNENK----CKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAE---DKRSCIPP---NKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCD-----------FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKC---VNS-KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKD------------------------------------TMCNPH-CLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
C C GW G+ C E C +G + R F C C + +T C L+ S C G C GR C C GF G C +++ CS +G CEH CVN E +FQC+C G+ + + D C+ C T + C C G+ G +C D+D+C C +C +T+ + C+C+ GF+ + +CA N K D NG C C G+ G C +I+ C+ + C++ S+ C C G+T Q+N+ C S C L +K C+C G G NCE N +PC++ C + C C PG+ K + EC GTC + + C CP+GF C + ++EC + C I + C C+ G D+ C+P N TC+DK ++G C C+ G+ G C +INEC + + C++ S+ C C L + +C V + C C +C C+ GW G+LC++D++EC+ N K + C N+ G + CSC F T + + ND +PC +GG C VNS C C PG+ G C +INECQ K+G G C + +Y C C PG+ + C+I+ D CN CLNGGVC+D RC CP G+ G C VD C+R +PC G C SF C+C + + Y
Sbjct: 124 CVCVNGWTGDDCS----ENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECS---IGANPCEHFGKCVNT-EGSFQCQCGRGYAGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTYCQTDIDDCESNPCVNDGVCRDTVNGFTCTCQPGFSGTMCQIDIDECASTPCQNGAKCHDRPNGFECRCAEGYEGTLCESNINNCQPDPCHHGTCIDGIASYTCNCDPGYTGYRCENQLNE--CHSNPCQNSGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYDCVCKPGF--TGPKCNVEIDECASSPCRNGGTCVDEENGFHCLCPEGFKPPYCYSQVDECGSSPCVHGSCREDINGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDK--LNG----FTCKCRQGFIGNLCQVNINECASNPCLNKGTCVDGVASFTCVCE----LPYSGPTCAEVLTPCSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECISNPCKNRGTCTNTLGGFVCSCRAGFTGLTCE----TDINDCVPNPCLSGGSCTDGVNSYHCSCLPGFTGSRCALEINECQSNPCKNG--GTCTDYVNSYTCTCRPGFTGIH----CEINIPDCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYTGNRCQTPVDWCRRSSPCQN-GGRCRQNDASFTCECKNGWSGHY 897 HSP 2 Score: 189.889 bits (481), Expect = 1.995e-48 Identity = 225/786 (28.63%), Postives = 332/786 (42.24%), Query Frame = 1
Query: 1024 CQNGGTCFQG-----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQ---SGFQLDNDGKSCIKE--ECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAIN--CLNN-CNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHN-------CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTC----------NENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGH-------KLAE-------DKRSCI-------------------PPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILS---ANSHSCQSVCSLCKNGKC--DFNN-KCKCKTGWTGELCDVDIDECL-------------------------------LNQHKCQHN-------CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS------KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
C NGGTC Q C C GFEG C+ ++ C + N +CV +G N + C+C +G D C+ + C GT + C C GW G C++++D+C VC C + + S+ C C G T L C ++ C++N CN+ C LNG IC C +G+ G C+ D+DEC + CEH CVN GSF CQC G+ +I+ +C+S C + + C C PGY G C+ + I CE N C + C+C PG+ T +++ +C C N +C+C +G+ G LCE++IN C C + I S+ C C G+ +L E + C+ N C C +G C + C+CK G+ G +C+ +I+EC C++ E + C C GF + C S S C +G C D N +C C+ GW G+ CD+D ++CL +N ++C N CV+ S++C C LP+ G +C E CS +PC N C ++ +C C+PG+ G C D+NEC K+ G C NT G + C C G+ L TC+ D + NP CL+GG C D C C GF G C ++++ECQ PC K G C + S+ C C + ++
Sbjct: 30 CLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNGG---LCV-DGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGL---LCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYAGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTYCQTD-----IDDCESNPCVNDGVCRDTVNGFTCTCQPGF-----SGTMCQIDIDECASTPCQNGAKCHDRPNGFECRCAEGYEGTLCESNINNCQPDPCHHGTCIDGIASYTCNCDPGYTGYRCENQLNECHSNPCQNSGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYDCVCKPGFTGPKCNVEIDECASSPCRNGGTCVDEENGFHCLCPEGFKPPYCYSQVDECGS--SPCVHGSCREDINGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQGFIGNLCQVNINECASNPCLNKGTCVDGVASFTCVCELPY-----SGPTCAEVLTPCSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECISNPCKN--RGTCTNTLGGFVCSCRAGFTGL----TCETDINDCVPNP-CLSGGSCTDGVNSYHCSCLPGFTGSRCALEINECQS-NPC-KNGGTCTDYVNSYTCTCRPGFTGIH 782 HSP 3 Score: 189.504 bits (480), Expect = 2.272e-48 Identity = 225/784 (28.70%), Postives = 324/784 (41.33%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFC-VHGCSFDKRKLD----FSCICGIKETQNNC-LELRTCSKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-------QLDNDGKS-CIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKN-----GDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH-LCVNVPG--SFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCK-------NGKCDFNNK---CKCKTGWTGELCDVDIDEC--------LLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCV----NSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVL---DDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDEC 2874
I+NC PD HG C+ C C+ G+ G RC + +L C + C + +D + C C + NC + C+ + G C G C C GF G +C +EI+ C+ N CV+E EN F C C GF Q+D G S C+ C + ++ C C+ GW GK C+ D ++CL CQ C++ + + C CR+GF C +N +N C N G C++G+ C C + G C+ + C N H +C + + C C G+ Q I+ +CIS C N G C C C G+ G CE T IND + CL G C G N C C GF G C +INEC + C++ CT+ + S+ C C+ G + + IP DC CFN C C+SG+ G C ++NEC + C + S++C+C G+ + CQ+ C+ G+C N+ C+CK GW+G CD+ C + C H +CVN+ ++ C C + G C + D C PC+NG C +C C PG+ G +CE +INECQ ++G G C + G+Y C CPPG L + ++ C + P CLN G C D RC CP GF G C D++EC
Sbjct: 370 INNCQPDPCHHGTCIDGIASYTCNCDPGYTGYRC---------ENQLNECHSNPCQNSGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINRYDCVCKPGFTGPKCNVEIDECASSPCRNGG---TCVDE-ENGFHCLCPEGFKPPYCYSQVDECGSSPCVHGSCRE----DINGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQGFI---GNLCQVN-INECASNPCLNKGTCVDGVASFTCVCELPYSGPTCAEVLTPCSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECISNPCK----NRGTCTNTLGGFVCSCRAGFTGLTCE---------------TDINDCVPNPCLSGG---------------SCTDGV-NSYHCSCLPGFTGSRCALEINECQSNP-CKNGGTCTDYVNSYTCTCRPGFTGIHCEIN-IP---------DCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYT----GNRCQTPVDWCRRSSPCQNGGRCRQNDASFTCECKNGWSGHYCDIPRVSCETAARQRGIQTDELCHHGGHCVNTGNTHFCKCPADYT-----GSYCESQVDHCEDKPCRNGATCRPYVGGYQCDCMPGFMGQNCEREINECQSHPCQNG--GTCIDLVGHYICSCPPGTLGVLCEINEDDCNTPVRPRNAPPKCLNNGTCVDRVGGYRCNCPPGFTGERCEGDINEC 1075 HSP 4 Score: 170.244 bits (430), Expect = 2.434e-42 Identity = 209/733 (28.51%), Postives = 309/733 (42.16%), Query Frame = 1
Query: 1168 ENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT---TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCL---NNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK----YNHGCEHLCVNVPGSFNCQCHSGFTLQI--NKKKCISKSCN------IECLN------------GGLCDKD------------------------KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKKLECPKCV-----RGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHK--LAEDKRSCIPPNKKTCLDKDCVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHF--CMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFN--------NKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSC----NLPFYLSTVD----------------------------GRSC-LEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPH-CLNGGVCRDMS-----RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLM 2967
+ +F+C+CQ G+ + C +C GT T S C C G++G C +VD+C C +CV+ + +Y C C +T + CL N C+ G C N I C C +GW G+DCS +ID+C +N C + SF C+C G T + C+S CN LN GG C++D +C+C GY G CE + PC+++ T ++ C C+PGY + E CV R T N C C GF+G +C+ DI+EC + T CQ+ C + F CRC G++ L E N C C HG C + C C GY G RC+ +NEC +S+ C++ C++ Y C C G + +C+ C + CD+ C CK G+TG C+V+IDEC + + CV+ + C C P+ S VD G++C L++ND SPC+N G C++ CKC+ G+ G+ C+ +INEC + + C+ G C + ++ C+C Y TC + T C+P+ C N VC + +C C G+ G C +DV+EC PC K RG C NT G F C C + + +
Sbjct: 2 KGSFRCQCQPGYSGRICEVPTLPCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNGGLCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGA---TCHDRVASFFCECPVGKTGLLCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYAGPRCEIDINECLSMPCQNDATCLDRIGEFTCICMPGYTGTYCQTDIDDCESNPCVNDGVCRDTVNGFTCTCQPGFSGTMCQIDIDECAS-TPCQNGAKCHDRPNGFECRCAEGYEGTLCES-------NINNCQPDPCHHGTCIDGIASYTCNCDPGYTGYRCENQLNEC--HSNPCQNSGKCVDLVNKYICQCQHG----TSGTNCEINFDDCASNPCDYGICKDGINRYDCVCKPGFTGPKCNVEIDECASSPCRNGGTCVDEENGFHCLCPEGFKPPYCYSQVDECGSSPCVHGSCREDINGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQGFIGNLCQVNINEC----ASNPCLNKGTCVDGVASFTCVCELPY----SGPTC--AEVLTPCSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECIS-NPC-KNRGTCTNTLGGFVCSCRAGFTGL 705 HSP 5 Score: 111.309 bits (277), Expect = 3.378e-24 Identity = 168/622 (27.01%), Postives = 249/622 (40.03%), Query Frame = 1
Query: 778 AIDNCVPD-CGEHGICVKS------RCYCETGWFGERCVILEPE----LCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNR-TCEHICVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT-TEVVSG-NCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG----------ICYCFSGWHGEDCSLDIDEC---------KYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGY-----DLMPD---KKTCKKLECPKCVR-GTCNEN----KCKCPKGFAGLLCENDINECLNQTIC---QHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNK-KTCLDKDCVHGQC--------FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCS--LCKNGKCDFNN------KCKCKTGWTGELCD 2388
+ C P+ C H +C + +C C+ GW G+ C I E CK R G F C C T C ++ C C +GG+C G C C GF G +C LEIN C N TC N++ C C+ GF + + C + C GT T+ ++G +C C+ G+ G C +V+EC C +C + + S++C+C +G+T G ++ C ++ C NG C C +GW G C + C + + C H CVN + C+C + +T + + + + C NG C +C C PG++G NCE PC++ T I+ + +CSC PG ++ D + PKC+ GTC + +C CP GF G CE DINECL+ C + C CK G R C NK C + C +G C C+ GY G C+ ++ C++ S C T +CSC+PG+ H CS C+NG C+C W G+ C+
Sbjct: 632 VLTPCSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECISNPCKNRGTCTNTLG--------GFVCSCRAGFTGLTCETDINDCVPNPCLSGGSCTDGVNSYHCSCLPGFTGSRCALEINECQSNPCKNGGTCTDYV-----NSYTCTCRPGFTGIHCEINIPDCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYT----GNRCQTPVDWCRRSSPCQNGGRCRQNDASFTCECKNGWSGHYCDIPRVSCETAARQRGIQTDELCHHGGHCVNTGNTHFCKCPADYTGSYCESQ-VDHCEDKPCRNGATCRPYVGGYQCDCMPGFMGQNCEREINECQSHPCQNGGTCIDLVGHYICSCPPGTLGVLCEINEDDCNTPVRPRNAPPKCLNNGTCVDRVGGYRCNCPPGFTGERCEGDINECLSNPCSPSNSFDCIQLPNDYQCVCKPGFT----GRRCQ--NKFSVCESQPCQNGGACSVSSSSPLGYTCTCQLGYIGPNCERSMS-CRELSCYNGGSCTLTSRGARCSCLPGYGGPQCQHRSTEGCSSKPCRNGGVCTEETSYPYFSCQCSKDWAGKRCE 1228
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Match: notch1a (neurogenic locus notch homolog protein 1 [Source:NCBI gene;Acc:101171596]) HSP 1 Score: 198.364 bits (503), Expect = 3.999e-51 Identity = 218/713 (30.58%), Postives = 327/713 (45.86%), Query Frame = 1
Query: 1024 CQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICV-NEGENNFQCKCQSGF-----QLDNDGKSCIKEECSKFGT--TEVVSGN--CKCKQGWKGKFCNDDVDECLFPV--CQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK----YNHGCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEH-NCTTINDNMVCSCLPGYD-LMPDKKTCKKLECPKCVRGTCNENK----CKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHK-----LAEDKRSCIP-PNKKTCLDKDCVHGQCFNS-KCICKSGYRGKRCDEDINECKKYSHICEH-FCMNTEGSYKCSCMPGFILS---ANSHSCQSVCSLCKNGKC--DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSC-LEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY 2970
CQNGGTC C C G+ GD C I+ C+ C H ++ +F C+C G LD+ +CI C K T V+G C C G+ G CN D+DEC C+ C+NT+GS+QC C +G+ +C ++ C++N C + CL+ I C C G+ G C +D DEC N+G C++ SF C+C GF+ Q++ +C S C +C +G +K C+C GY G +CE + + PC + C + C C PGY + + + L P GTC + + C CPKG AG CE ++++C +Q C + I + C C+ G+ + D + P N TC+D NS C+C GY C ++EC S+ C H C + YKC+C G+ N + C S + C NG D + C C+ G+TG C +I+EC N Q C++ Y C+C LP+ G++C ++ N+ SPC NG C+N+ +CKC+PG+ G CE DI++C+ +G G C + ++ C C PG+ C+ + NP C NG C D C CP GF GI+C ++ ++C + + G C + SF C C + + Y
Sbjct: 275 CQNGGTCHDTHGSYHCVCVNGWTGDDCSKNIDDCAAA-----ACFHGATCHDRVASFFCECPHGRTGLLCHLDD---ACISNPCQKGSNCDTNPVNGKAICTCPPGYTGSACNLDIDECALGANPCEHGGRCLNTLGSFQCKCLQGY---EGPRCEMDVNECMSNPCQNDATCLDQIGGFHCICMPGYEGVFCHIDTDECASQPCLNNG---KCIDKINSFYCECPKGFSGNLCQVDIDECASTPCRNGAKCTDGP--NKYNCECAEGYTGQHCEIDINECYSDPCHYGTCKDGLASFTCYCRPGYTGRLCETNINECLSQPCKNGGTCQDRENSYICSCPKGTAGFNCEINLDDCKSQPCDYGRCIDKINGYECACRPGYTGTMCNINIDDCAINPCHNGGTCIDG-------INSFTCLCPEGYNDATCLSQVDECS--SNPCIHGLCQDLINGYKCTCDSGWSGQNCDINKNECDS--NPCMNGGTCKDMTSGYHCTCRVGFTGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYT-----GQTCEIDINECVKSPCWNGAFCLNTMGGYQCKCQPGFTGQKCETDIDDCKPNPCSNG--GLCHDGISSFTCTCLPGFR----GGRCEQDINECESNP-CKNGANCTDCVNSYTCTCPTGFSGINCEINTNDCTDSSCFNG--GTCVDGINSFTCLCLTGFTGSY 946 HSP 2 Score: 189.119 bits (479), Expect = 2.819e-48 Identity = 241/841 (28.66%), Postives = 348/841 (41.38%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG---CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDEC-LFP-VCQQ--ICVNTIGSYQCSCREGFT-------------------------------LLSNGKCAINC-------LNNCNKNGDC----LNG--ICYCFSGWHGEDCSLDIDECKYN-HGCEH--LCVNVPGSFNCQCHSGFTL---QINKKKCISKSC--NIECLN--GGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDL---MPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGH--KLAE-DKRSCIP---PNKKTCLDKD---------------------------CVHGQCFNS----KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKC------DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRD---MSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
RC C GW G+ C P C C +G + C C C L++ C++ C NGG C C+C + + G CQ CS N CV +G+ + C C GF +++ C C G V + NC+C + G++C ++VDEC + P VCQ C +T GSY C C G+T +G+ + C N C K +C +NG IC C G+ G C+LDIDEC + CEH C+N GSF C+C G+ +++ +C+S C + CL+ GG C C PGY G C + PC +N I+ ++ C C G+ D C C KC G N+ C+C +G+ G CE DINEC + C + + SF C C+ G+ +L E + C+ N TC D++ C +G+C + +C C+ GY G C+ +I++C C++ S+ C C G+ N +C S C + C D N KC C +GW+G+ CD++ +EC N C + Y C+C + F G +C + C+S PC N G C++ KC C Y G +CE DINEC +G C NT G Y+C C PG+ + C+ D NP C NGG+C D C C GF G C D++EC+ PC K C + S+ C C + +
Sbjct: 95 RCQCPPGWTGKSCQT--PNPCASNP---CANGGQCSSLDSTYRCTCPPNFHGQTCKLDVNECAQTPYLCLNGGICVNEVGSYHCRCPQEYTGQHCQTPYVPCSPSPCQNGG---TCVQKGDTTYDCSCLPGFMGQHCEHNIDDCPGHNCQNGGVCADGVNTYNCQCPPHYTGQYCTENVDECEMMPNVCQNGGTCHDTHGSYHCVCVNGWTGDDCSKNIDDCAAAACFHGATCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPPGYTGSACNLDIDECALGANPCEHGGRCLNTLGSFQCKCLQGYEGPRCEMDVNECMSNPCQNDATCLDQIGGF----HCICMPGYEGVFCHIDTDECASQPCLNNGKCIDKINSFYCECPKGFSGNLCQVDIDECASTPCRNGAKCTDGP-NKYNCECAEGYTGQHCEIDINECYSDPCHYGTCKDGLASFTCYCRPGYTGRLCETNINECLSQPCKNGGTCQDRENSYICSCPKGTAGFNCEINLDDCKSQPCDYGRCIDKINGYECACRPGYTGTMCNINIDDCAINPCHNGGTCIDGINSFTCLCPEGY----NDATCLSQVDECSSNPCIHGLCQDLINGYKCTCDSGWSGQNCDINKNECDSNPCMNGGTCKDMTSGYHCTCRVGFT-----GPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGQTCEIDINECVKSPCWNGAF--CLNTMGGYQCKCQPGFT----GQKCETDIDDCKPNP-CSNGGLCHDGISSFTCTCLPGFRGGRCEQDINECES-NPC-KNGANCTDCVNSYTCTCPTGF 904 HSP 3 Score: 187.578 bits (475), Expect = 1.009e-47 Identity = 226/757 (29.85%), Postives = 329/757 (43.46%), Query Frame = 1
Query: 952 DFSCICGIKETQNNCLELRTC-SKGCQNGGTCFQ----GRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEH--ICVNEGENNFQCKCQ---SGFQLDNDGKSCIKEECSKFGT---TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINC---LNNCNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTLQI--NKKKCISKSCN--IECLNGGLCDKDKCKCPPGYIGHNCEFN-DFCHF-ISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENK----------CKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNGH-----KLAEDKRSCIP-PNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEH-FCMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKC--DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHN-CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI-GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC-MTMKEAVLKP 3015
DF C C T +C C S C NGG C RC C F G C+L++N C++ C + ICVNE ++ C+C +G C C GT + +C C G+ G+ C ++D+C CQ +C + + +Y C C +T + C N C G C + C C +GW G+DCS +ID+C HG C + SF C+C G T + CIS C C + K C CPPGY G C + D C +PCEH C + C CL GY + C +++ +C+ C + C C G+ G+ C D +EC +Q + C + I SF+C C G ++ D+ + P N C D + C C GY G+ C+ DINEC YS C + C + S+ C C PG+ + N + C S CKNG D N C C G G C++++D+C C + C++ Y C+C P Y T+ C D C+ +PC NGG C++ C C GYN +C ++EC S + CI G C++ Y+C C G+ + C I+ + NP C+NGG C+DM+ C C +GF G +C +++EC PC +G C + + C C +L Y G +C + + E V P
Sbjct: 93 DFRCQCPPGWTGKSCQTPNPCASNPCANGGQCSSLDSTYRCTCPPNFHGQTCKLDVNECAQTPY---LCLNGGICVNE-VGSYHCRCPQEYTGQHCQTPYVPCSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHCEHNIDDCPGHNCQNGGVCADGVNTYNCQCPPHYTGQYCTENVDECEMMPNVCQNGGTCHDTHGSYHCVCVNGWTGDDCSKNIDDCAAAACFHGA--TCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPPGYTGSACNLDIDECALGANPCEHGGRCLNTLGSFQCKCLQGY----EGPRC-EMDVNECMSNPCQNDATCLDQIGGFHCICMPGYEGVFCHIDTDECASQPCLNNGKCIDKINSFYCECPKGFSGNLCQVDIDECASTPCRNGAKCTDGPNKY------NCECAEGYTGQHCEIDINEC--YSDPCHYGTCKDGLASFTCYCRPGYTGRLCETNINECLS--QPCKNGGTCQDRENSYICSCPKGTAGFNCEINLDDC--KSQPCDYGRCIDKINGYECACR-PGYTGTM----CNINIDDCAINPCHNGGTCIDGINSFTCLCPEGYNDATCLSQVDEC----SSNPCIHGLCQDLINGYKCTCDSGW----SGQNCDINKNECDSNP-CMNGGTCKDMTSGYHCTCRVGFTGPNCQTNINECAS-NPCLN-QGTCIDDVAGYKCNC----LLPYTGQTCEIDINECVKSP 806 HSP 4 Score: 184.882 bits (468), Expect = 7.595e-47 Identity = 234/819 (28.57%), Postives = 340/819 (41.51%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAIN----CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQ---INKKKCISKSCNIECLNGGLCDKD-----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIND--NMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----------KCKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGHKLA---EDKRSCIP---PNKKTCLD----------------------KDCVHGQCFNS----------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCD---------FNNKCKCKTGWTGELCDVDIDECLL--NQHKCQHN--------CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGY------LVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGI--CYNTYGSFYCQCSSNYV 2961
C C G+ G C I E Q L +G DK F C C + N C +++ C S C+NG C G C+C EG+ G C+++IN C + C + +G +F C C+ G+ + + C+ + C GT + + C C +G G C ++D+C C C++ I Y+C+CR G+T C IN +N C+ G C++GI C C G++ C +DEC N LC ++ + C C SG++ Q INK +C S C +NGG C KD C C G+ G NC+ N +PC + T I+D C+CL Y +TC+ ++ +CV+ C +CKC GF G CE DI++C N +C + I SF C C G + +D C N C D DC CFN C+C +G+ G C DINEC + C++ G+YKC+C G+ +CQ + C + C + C+C+TGWTG CD+ C + Q + N C+++ ++ C C + G C E+ D C PGY+G +C ++INECQ ++G G C + Y+C CP G + LDD C P C N G C D +C CP G+ G C DV+EC PCD RG C S+ C+C + Y
Sbjct: 444 HCICMPGYEGVFCHIDTDECASQPCL---NNGKCIDKIN-SFYCECPKGFSGNLCQVDIDECASTPCRNGAKCTDGPNKYNCECAEGYTGQHCEIDINECY-----SDPCHYGTCKDGLASFTCYCRPGYTGRLCETNINECLSQPCKNGGTCQDRENSYICSCPKGTAGFNCEINLDDCKSQPCDYGRCIDKINGYECACRPGYT---GTMCNINIDDCAINPCHNGGTCIDGINSFTCLCPEGYNDATCLSQVDECSSNPCIHGLCQDLINGYKCTCDSGWSGQNCDINKNECDSNPC----MNGGTC-KDMTSGYHCTCRVGFTGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYT----GQTCE-IDINECVKSPCWNGAFCLNTMGGYQCKCQPGFTGQKCETDIDDCKPNPCSNGGLCHDGISSFTCTCLPGFRGGRCEQDINECESNPCKNGANCTDCVNSYTCTCPTGFSGINCEINTNDCTDSSCFNGGTCVDGINSFTCLCLTGFTGSYCQFDINECDSKPCLNGGTCLDGYGTYKCTCPHGYT----GVNCQHLVRWCDSSPCKNGGTCWQQGASYTCQCQTGWTGLYCDIPSVSCEVAAKQQGVEVNQLCRNSGQCLDAGSTHHCRCQAGYT-----GSYCQEQVDE-------------RILSCVPGYHGVNCSKEINECQSQPCQNG--GTCIDLINTYKCSCPRGTQGVHCEMNLDD---CNPFNDPFTNEPKCFNNGRCVDRIGGYQCMCPPGYVGERCEGDVNECLS-DPCDP-RGSYNCIQLMNSYRCECRTGYT 1211 HSP 5 Score: 154.836 bits (390), Expect = 1.352e-37 Identity = 202/730 (27.67%), Postives = 287/730 (39.32%), Query Frame = 1
Query: 949 LDFSCICGIKETQNNCLELRT---CSKGCQNGGTC-----FQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQSGFQLDNDGKSCIKE--ECSKFG---------TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNT-IGSYQCSCREGFTLLSNGKCAINCL-NNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKY-NHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFNDFCHFISPCE--HNCTT--INDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGF---ILSANSHSCQSVCSLCKNGKC-DFNNK--CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCY---CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
DF C C + T CL S C+NGGTC RCQC G+ G CQ N C+ + C N G+ + ++C C F G++C + EC++ EV S +C+C Q + G+ C C CQ CV +Y CSC GF +C +NC G C +G+ C C + G+ C+ ++DEC+ + C++ C + GS++C C +G+T + K I C +G C C+CP G G C +D C +PC+ NC T +N +C+C P G+ G C DI+EC L C+H C NT+GSF C+C GY G RC+ D+NEC + C++ G + C CMPG+ ++ C S L NGKC D N C+C G++G LC VDIDEC S+PC+NG KC + C+C GY G CE DINEC S G C++ ++ C C PGY + C+ + + + P C NGG C+D Y CP G G +C +++D+C + PCD G C + + C C Y
Sbjct: 52 FDFLCECPLGFTDRLCLTPTNHACMSAPCRNGGTCELIALTDFRCQCPPGWTGKSCQTP-NPCA---------SNPCANGGQCSSLDSTYRCTCPPNFH----GQTCKLDVNECAQTPYLCLNGGICVNEVGSYHCRCPQEYTGQHCQTPYVPCSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHCEHNIDDCPGHNCQNGGVCADGVNTYNCQCPPHYTGQYCTENVDECEMMPNVCQNGGTCHDTHGSYHCVCVNGWTGD-DCSKNIDDCAAAACFHGATCHDRVASFFCECPHGRTGLLCHLDDAC-ISNPCQKGSNCDTNPVNGKAICTC---------------------------------PPGYTGSACNLDIDECALGANPCEHGGRCLNTLGSFQCKCLQ--------------------------------------GYEGPRCEMDVNECMSNPCQNDATCLDQIGGFHCICMPGYEGVFCHIDTDECASQPCL-NNGKCIDKINSFYCECPKGFSGNLCQVDIDECA------------------------------------------STPCRNGAKCTDGPNKYNCECAEGYTGQHCEIDINEC---YSDPCHYGTCKDGLASFTCYCRPGYT----GRLCETNINECLSQP-CKNGGTCQDRENSYICSCPKGTAGFNCEINLDDC-KSQPCD--YGRCIDKINGYECACRPGYT 640 HSP 6 Score: 141.354 bits (355), Expect = 1.771e-33 Identity = 191/697 (27.40%), Postives = 289/697 (41.46%), Query Frame = 1
Query: 754 EVVCLNKPAIDNCVPDCGEHGICVK----SRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF---QLDNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQI--CVNTIGSYQCSCREGFTLLSNGKCAINCLN----NCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK----YNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVC----SCLPGYDLMPDKKTCKKLECPKCVRGT-----CNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLAE---DKRSCIPPNKKTCLDKDCVH-GQCFNS----KCICKSGYRGKRCDEDINECKKYSHICE----HFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKC------------KCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC--SSPCKNGGKCVNS------KCKCKPGYNGDSCE 2616
+ CL++ +D C + HG+C +C C++GW G+ C I + E C C++G + + C C + T NC + C S C N GTC +C C + G C+++IN C + N C+N +QCKCQ GF + + D C CS G + S C C G++G C D++EC C+ C + + SY C+C GF+ ++ C IN + +C G C++GI C C +G+ G C DI+EC N G C++ G++ C C G+T +N + + + C NGG C + C+C G+ G C+ ++ + + N +C CL D + C G+ +E C G+ G+ C +INEC +Q CQ+ C + I ++ C C G + + C P N + C + G+C + +C+C GY G+RC+ D+NEC S C+ + C+ SY+C C G+ C V CK C C KC G+TG C+ D C K CV+ + C C F G C DS S+PC NGG C + KC C +NG C
Sbjct: 679 DATCLSQ--VDECSSNPCIHGLCQDLINGYKCTCDSGWSGQNCDINKNE-CDSNP---CMNGGTCKDMTSGYHCTCRVGFTGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGQTCEIDINECVKSPCWNGA---FCLNT-MGGYQCKCQPGFTGQKCETDIDDCKPNPCSNGGLCHDGISSFTCTCLPGFRGGRCEQDINECESNPCKNGANCTDCVNSYTCTCPTGFSGIN---CEINTNDCTDSSCFNGGTCVDGINSFTCLCLTGFTGSYCQFDINECDSKPCLNGG---TCLDGYGTYKCTCPHGYT-GVNCQHLVRWCDSSPCKNGGTCWQQGASYTCQCQTGWTGLYCDIPSVSCEVAAKQQG---VEVNQLCRNSGQCL-------DAGSTHHCRCQAGYTGSYCQEQVDERILSCVPGYHGVNCSKEINECQSQP-CQNGGTCIDLINTYKCSCPRGTQGVHCEMNLDDCNPFNDPFTNEPKCFNNGRCVDRIGGYQCMCPPGYVGERCEGDVNEC--LSDPCDPRGSYNCIQLMNSYRCECRTGYT----GQRCDKVFDGCKGRPCRNGGTCAVASNTPHGFICKCPPGFTGSSCEYDSHSCGSLNCKNGGTCVSGHLGPRCLCPSAFT-----GPECETPTDSLCISNPCYNGGTCQTTPNAPFFKCSCPSNFNGLLCH 1336 HSP 7 Score: 117.857 bits (294), Expect = 3.253e-26 Identity = 136/472 (28.81%), Postives = 201/472 (42.58%), Query Frame = 1
Query: 1708 KCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINE------CLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHG-QCFN----SKCICKSGYRGKRCDEDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQS-----VCSLCKNG-----KCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS---SPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVL----DDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYA-PCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC-MTMKEAVLKP 3015
+CP YIG+ C++ C SPC + C RG + C+CP GF LC N C N C+ + + F C+C G +SC PN C C +G QC + +C C + G+ C D+NEC + ++C + C+N GSY C C + CQ+ S C+NG K D C C G+ G+ C+ +ID+C H CQ+ V ++G + +C P + + G+ C E D C + C+NGG C ++ C C G+ GD C ++I++C HG C + ++ C CP G L DD K + C+ + +NG + C CP G+ G C +D+DEC A PC+ G C NT GSF C+C + Y+G C M + E + P
Sbjct: 16 RCPSDYIGNRCQYPSPCS-PSPCRNG---------------------------GRCRAVSRGNTFDFLCECPLGFTDRLCLTPTNHACMSAPCRNGGTCELI---ALTDFRCQCPPGWT----GKSCQTPNP--CASNPCANGGQCSSLDSTYRCTCPPNFHGQTCKLDVNECAQTPYLCLNGGICVNEVGSYHCRCPQEYT----GQHCQTPYVPCSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHCEHNIDDCP--GHNCQNGGVCADGVNTYNCQCPPHYT---GQYCTENVDECEMMPNVCQNGGTCHDTHGSYHCVCVNGWTGDDCSKNIDDCAAAACFHG--ATCHDRVASFFCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNG-----KAICTCPPGYTGSACNLDIDECALGANPCEH-GGRCLNTLGSFQCKC----LQGYEGPRCEMDVNECMSNP 429
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Match: notch1b (notch receptor 1 [Source:NCBI gene;Acc:101161732]) HSP 1 Score: 194.897 bits (494), Expect = 5.488e-50 Identity = 238/781 (30.47%), Postives = 342/781 (43.79%), Query Frame = 1
Query: 832 RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRT--CSKG-CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKE--ECSK----FGTTE--VVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAIN---CLNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFT-----LQINKKKCISKSCNIECLNGGLCDKD---KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECL-NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQC-------FNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQ----SVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGI-----------CYNTYGSFYCQCSSNYVLMY 2970
+C C+ G+ G RC + E C + + + DF CIC + + E+ T C+ G C N G C C+C GF G CQ +I+ C+ N +G N + C+C G+ G+ C E ECS +GT + + S +C C G+ G+ C +++ECL C+ C + +Y CSC +G ++ C IN C NN KNG C++ I C C G+ G C++DIDEC N C + C++ +F C+C G+ Q+N+ C+S C ++G DK KC C G+ G NC+ N+ + CE N C+ G TCK + + C C GF G C+ +INEC N + Q C + + + C C + E+ + + P C K C HG + C C G++G+ C+ DI EC K + C NT GSY CSC PGF AN C+ + LCK+ DF C C G+ G C+ DI+EC + K NC + SY+C+C F G +C C+ S C NGG CV+ C C PG+ G+ C+ DINEC +G G C++++G Y+C CP GY L+ CQ +P C NGG C RC C G+ G+ C V C+ A K RG+ C + C C + Y Y
Sbjct: 437 QCKCQRGYVGPRCEMDVNECISNP----CKNEATCLDQIGDFQCIC-MPGYEGEFCEINTDECANGPCLNSGKCIDKINGFHCECPTGFTGSLCQTDIDECASTPCKNGAK----CTDGPNKYTCECTEGYA----GQHCETEINECSSDPCHYGTCKDGLASFSCDCTPGYTGRLCETNINECLSLPCRNGGTCQDRPNAYICSCPKGTGGIN---CEINIDDCKNNLCKNGTCIDRINGYECACEPGYTGTMCNIDIDECAANP-CRNGGTCIDGINAFTCKCPDGYQDPTCFSQVNE--CLSNPC----IHGHCEDKINGYKCLCDSGWSGKNCDINN-----NECESN----------PCMNG-------GTCKDMT---------SGYVCTCRMGFTGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCVLPYT-GENCETLMAP----CHSKPCKHGGVCRESEDYLSFSCACPEGWQGQTCEVDIKECVKNPCLNGATCQNTLGSYHCSCKPGFTGRNCEANMDDCKPNPCNNGGLCKDEVNDF--LCTCLLGFRGTTCEEDINECESSPCKNGANCTDCVNSYTCTCPAGF-----SGINCENNTPDCTESSCFNGGTCVDGINAFTCLCPPGFTGNYCQHDINECDSKPCMNG--GTCQDSYGTYKCTCPHGYTGLN----CQDLVNWCNSSP-CKNGGSCSQSGTTYRCNCETGWTGLYCDVPSVSCEVAA---KQRGVDITQLCRNAGRCLDAGNVHRCHCQAGYTGSY 1141 HSP 2 Score: 191.045 bits (484), Expect = 7.068e-49 Identity = 217/737 (29.44%), Postives = 320/737 (43.42%), Query Frame = 1
Query: 1024 CQNGGTCFQG-----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF--QL---DNDGKSCIKEECSKFGTTEVVSGN--CKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLL---SNGKCAINC---LNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYN-HGCEHL--CVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTIN--DNMVCSCLPGYDL---MPDKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGH--KLAEDKRS---CIP-PNKKTCLDK----------------------DCVHGQCFNSKCI---------CKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFI-LSANSHSCQSVCSLCKNGKCD---FNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC 2985
C NGGTC Q C C GF G C IN C + N CV +G N + C+C+ F QL D D + C GT G+ C C GW G C+ ++D+C C + C + + S+ C C +G T L + C N +NC+ N N C C G+ G C D+DEC + CEH C+N GSF C+C G+ +++ +CIS C E +C C PGY G CE N PC ++ I+ + C C G+ D C C KC G N+ C+C +G+AG CE +INEC + C + + SF C C G+ +L E + +P N TC D+ DC + C N CI C+ GY G C+ DI+EC C++ ++ C C G+ + S + + + C +G C+ KC C +GW+G+ CD++ +EC N C + Y C+C + F G +C + C+S PC N G C++ KC C Y G++CE + C KHG + + ++ C CP G+ +TC++ K+ + NP CLNG C++ C C GF G +C ++D+C + PC+ G+C + F C C +L + GT+C
Sbjct: 227 CLNGGTCIQKGETSYECSCVPGFTGKNCSSNINDCPGHECQNGG---TCV-DGVNTYNCQCKPEFTGQLCMDDVDECQLMPNACQNGGTCHNTYGSYQCVCVNGWTGNDCSKNIDDCADAACYKGSTCHDRVASFYCECPKGRTGLLCQLDDACISNPCQKGSNCDTNPITGNHFCTCPPGYFGPSCDKDVDECSLGPNPCEHAGKCLNTKGSFQCKCQRGYVGPRCEMDVNECISNPCKNEATCLDQIGDFQCICMPGYEGEFCEINTDECANGPCLNSGKCIDKINGFHCECPTGFTGSLCQTDIDECASTPCKNGAKCTDGP-NKYTCECTEGYAGQHCETEINECSSDPCHYGTCKDGLASFSCDCTPGYTGRLCETNINECLSLPCRNGGTCQDRPNAYICSCPKGTGGINCEINIDDCKNNLCKNGTCIDRINGYECACEPGYTGTMCNIDIDECAANPCRNGGTCIDGINAFTCKCPDGYQDPTCFSQVNECLSNPCIHGHCEDKINGYKCLCDSGWSGKNCDINNNECESNPCMNGGTCKDMTSGYVCTCRMGFT-----GPNCQTNINECASNPCLNQGTCIDDVAGYKCNCVLPYTGENCETLMAPCHSKPCKHGGVCRESEDYLSFSCACPEGW----QGQTCEVDIKECVKNP-CLNGATCQNTLGSYHCSCKPGFTGRNCEANMDDC-KPNPCNN-GGLCKDEVNDFLCTC----LLGFRGTTC 942 HSP 3 Score: 179.489 bits (454), Expect = 3.702e-45 Identity = 218/767 (28.42%), Postives = 326/767 (42.50%), Query Frame = 1
Query: 913 FCVHGCSFDKRKLDFSCICGIKETQNNC-LELRTCSKG-CQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFGT-TEVVSGN-CKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-------CNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCE-HLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGT-----CNENKCKCPKGFAGLLCENDINECLNQT-ICQHVCTNTIGSFFCRCKNG-------HKLAE-DKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQ--------SVCSLCKN-GKC-DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVN----SKCKCKPGYNGDSCEEDINECQW---PISKHG-CI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGV-CRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLR--GICYNTYGSFYCQCSSNYVLM---YDGTSCMTMK 2997
C +G D R + C C T C +++ C+ C+NGGTC G C+C +G++ C ++N C + C H + N ++C C SG+ N + C C GT ++ SG C C+ G+ G C +++EC C Q C++ + Y+C+C +T + C + C ++ D L+ C C GW G+ C +DI EC N C N GS++C C GFT + N C CN NGGLC KD E NDF +C+CL G+ ++ + E C G N C CP GF+G+ CEN+ +C + C + I +F C C G H + E D + C+ N TC D + KC C GY G C + +N C C + +Y+C+C G+ S SC+ + LC+N G+C D N +C C+ G+TG C+ +DEC N + C + G YSC C LP +L T +E N+ S PC+NGG C++ KC C G G CE ++++C P++K C G+C + G Y CICP GY+ + C+ + + NP G + C ++ RC C G+ G C D C + PC + NT F C+C + YD +C +++
Sbjct: 649 LCKNGTCID-RINGYECACEPGYTGTMCNIDIDECAANPCRNGGTCIDGINAFTCKCPDGYQDPTCFSQVNECL-----SNPCIHGHCEDKINGYKCLCDSGWSGKNCDINNNECESNPCMNGGTCKDMTSGYVCTCRMGFTGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCVLPYTGENCETLMAPCHSKPCKHGGVCRESEDYLSFSCACPEGWQGQTCEVDIKECVKNPCLNGATCQNTLGSYHCSCKPGFTGRNCEANMDDCKPNPCN----NGGLC-KD-------------EVNDF------------------LCTCLLGFRGTTCEEDINECESSPCKNGANCTDCVNSYTCTCPAGFSGINCENNTPDCTESSCFNGGTCVDGINAFTCLCPPGFTGNYCQHDINECDSKPCM--NGGTCQDSYGTY------KCTCPHGYTGLNCQDLVNWCNSSPCKNGGSCSQSGTTYRCNCETGWTGLYCDVPSVSCEVAAKQRGVDITQLCRNAGRCLDAGNVHRCHCQAGYTGSYCEEQVDECTPNPCQNGATCTDFLGGYSCKC-LPGFLGT---NCSVEINECFSQPCQNGGTCIDLIDTYKCSCPRGTQGVHCEVNVDDCSPFTDPLTKEPKCFNKGKCVDRVGGYHCICPSGYV----GERCEGDVNECLSNPCDPRGTLSCIQLTNNYRCECRAGYTGQRCDTVFDGC-KSRPCRNGGTCAVASNTPHGFICRCPPGFTGSTCEYDSQTCGSLR 1356 HSP 4 Score: 166.777 bits (421), Expect = 3.073e-41 Identity = 220/788 (27.92%), Postives = 324/788 (41.12%), Query Frame = 1
Query: 916 CVHGCSFDKRKLDFSCICGIKETQNNC-LELRTC-SKGCQNGGTCFQGR----CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGE-----NNFQCKCQSGFQLDN---DGKSCIKEECSKFG----TTEVVSGNCKCKQGWKGKFCNDDVDECLFPVC--QQICVNTIGSYQCSCREGFTLLSNGKCAINC-LNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYN---HGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----KCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGH------------KLAEDKRSC----IPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQSVCSLCKNGKC--DFNN--KCKCKTGWTGELCDVDIDEC------LLNQHKC--QHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGG--KCV----NSKCKCKPGYNGDSCEEDINECQ-WPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVC---RDMSRCYCPIGFHGIDCGVDVDECQRYAPC------------DKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAV 3006
C+HG DK + C+C + NC + C S C NGGTC C C GF G CQ IN C+ + C+N+G ++C C + +N C + C G + + +S +C C +GW+G+ C D+ EC+ C C NT+GSY CSC+ GFT + +C N CN G C + + C C G+ G C DI+EC+ + +G C + S+ C C +GF+ IN + C NGG C + C CPPG+ G+ C+ H I+ C D K C GTC ++ KC CP G+ GL C++ +N C N + C++ C+ + ++ C C+ G ++A +R + N CLD VH +C C++GY G C+E ++EC C + G Y C C+PGF+ S + C S C+NG D + KC C G G C+V++D+C L + KC + CV+ G Y C C + +G + N+ S+PC G C+ N +C+C+ GY G C+ + C+ P G NT + C CPPG+ TC+ ++ T + C NGG C +C CP F G +C D PC R IC + C N G+S T+ E
Sbjct: 725 CIHGHCEDKIN-GYKCLCDSGWSGKNCDINNNECESNPCMNGGTCKDMTSGYVCTCRMGFTGPNCQTNINECA---------SNPCLNQGTCIDDVAGYKCNCVLPYTGENCETLMAPCHSKPCKHGGVCRESEDYLSFSCACPEGWQGQTCEVDIKECVKNPCLNGATCQNTLGSYHCSCKPGFTGRNCEANMDDCKPNPCNNGGLCKDEVNDFLCTCLLGFRGTTCEEDINECESSPCKNGAN--CTDCVNSYTCTCPAGFS-GINCENNTPDCTESSCFNGGTCVDGINAFTCLCPPGFTGNYCQ-----HDINEC-----------------------DSKPCMN-------GGTCQDSYGTYKCTCPHGYTGLNCQDLVNWC-NSSPCKNGGSCSQSGTTYRCNCETGWTGLYCDVPSVSCEVAAKQRGVDITQLCRNAGRCLDAGNVH------RCHCQAGYTGSYCEEQVDECTPNPCQNGATCTDFLGGYSCKCLPGFLGTNCSVEINECFS--QPCQNGGTCIDLIDTYKCSCPRGTQGVHCEVNVDDCSPFTDPLTKEPKCFNKGKCVDRVGGYHCICPSGYVGERCEG----DVNECLSNPCDPRGTLSCIQLTNNYRCECRAGYTGQRCDTVFDGCKSRPCRNGGTCAVASNTPHGFICRCPPGFT----GSTCEYDSQ-TCGSLRCRNGGTCISGHKSPKCLCPPSFTGPECRHPTDSACNSNPCYNGGTCELTPEAPYYRCICPFKFNGLLCHILDNGFPGGVGSSVPTLPEVT 1446 HSP 5 Score: 164.466 bits (415), Expect = 1.357e-40 Identity = 220/833 (26.41%), Postives = 330/833 (39.62%), Query Frame = 1
Query: 1051 GRCQCTEGFEGDQCQLEI-------------NSCSRGQMGNRTC--------------------------EHICVNEGENNFQCKCQSGFQLDNDGKS--CIKEECSKFGTTEVVSG--NCKCKQGWKGKFCNDDVDECLF--PVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG-----------ICYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNI---ECLNGGLCDKD----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPK------------CVRGTCNENK------------CKCPKGFAGLLCENDINEC-LNQTICQHV--CTNTIGSFFCRCKNGH---KLAEDKRSCIP---PNKKTCLDK----------------------DCVHGQCFNS-KCI---------CKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN--------KCKCKTGWTGELCDVDIDECL-------------------------------LNQHKCQHN------CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSR---CYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTM 2994
G C+C +G+ G +CQ + S+G + C E C EG ++C+C G ++ K+ C C+ G + C C + G+ C D++EC P+C+ +C+N +G Y+C C + NGK CN + CLNG C C G+ G++CS +I++C H C++ CV+ ++NCQC FT Q+ C + C NGG C +C C G+ G++C N I+D +C G D+ ECPK C+ C + C CP G+ G C+ D++EC L C+H C NT GSF C+C+ G+ + D CI N+ TCLD+ +C +G C NS KCI C +G+ G C DI+EC C + Y C C G+ A H C++ + C + C + C C G+TG LC+ +I+ECL +N C++N C++ Y C+C P Y T+ C D C++ PC+NGG C++ CKC GY +C +NEC +S G C + Y+C+C G+ K C I+ + NP C+NGG C+DM+ C C +GF G +C +++EC PC +G C + + C C VL Y G +C T+
Sbjct: 44 GECKCRDGYVGSRCQFHDPCNNSPCANGGTCRAVSKGNTVDFNCTCKLGFTDRRCMTPINTACFSSPCRNEGTCEPEGLQGYRCRCPPGLAGEDCSKADPCASNPCANGGRCSLFESFFICTCTPFFSGQTCKQDINECDIQPPLCKNGGLCINEVGGYRCQCPAEY----NGKHCETRYLPCNPS-PCLNGGTCIQKGETSYECSCVPGFTGKNCSSNINDCP-GHECQNGGTCVDGVNTYNCQCKPEFTGQLCMDDV--DECQLMPNACQNGGTCHNTYGSYQCVCVNGWTGNDCSKN---------------IDDCADAACYKGSTCH-DRVASFYCECPKGRTGLLCQLDDACISNPCQKGSNCDTNPITGNHFCTCPPGYFGPSCDKDVDECSLGPNPCEHAGKCLNTKGSFQCKCQRGYVGPRCEMDVNECISNPCKNEATCLDQIGDFQCICMPGYEGEFCEINTDECANGPCLNSGKCIDKINGFHCECPTGFTGSLCQTDIDECASTPCKNGAKCTDGPNKYTCECTEGY---AGQH-CETEINECSSDPCHYGTCKDGLASFSCDCTPGYTGRLCETNINECLSLPCRNGGTCQDRPNAYICSCPKGTGGINCEINIDDCKNNLCKNGTCIDRINGYECACE-PGYTGTM----CNIDIDECAANPCRNGGTCIDGINAFTCKCPDGYQDPTCFSQVNEC---LSNPCIHGHCEDKINGYKCLCDSGW----SGKNCDINNNECESNP-CMNGGTCKDMTSGYVCTCRMGFTGPNCQTNINECAS-NPCLN-QGTCIDDVAGYKCNC----VLPYTGENCETL 829 HSP 6 Score: 133.265 bits (334), Expect = 5.606e-31 Identity = 181/663 (27.30%), Postives = 260/663 (39.22%), Query Frame = 1
Query: 1153 CVNEG------ENNFQCKCQSGF-----QLDNDGKSCIKEECSKFGTTEVVSG------NCKCKQGWKGKFCNDDVDECLFPVCQQICVNT-------IGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG----ICYCFSGWHGEDCSLDIDECKYNHGC---EHLCVNVPGSFNCQCHSGFTLQINKKKCISK--SCNIE-CLNGGLCDKD-----KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINEC-LNQTICQH--VCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPG-------FILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQH--NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNS----KCKCKPGYNGDSCEEDINECQWPISKHGCI--GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYV 2961
C+N+G + N +CKC+ G+ Q + C C+ GT VS NC CK G+ + C ++ F C N + Y+C C G K N C G C IC C + G+ C DI+EC LC+N G + CQC + + N K C ++ CN CLNGG C + +C C PG+ G NC N IND PG++ CV G N C+C F G LC +D++EC L CQ+ C NT GS+ +C+C +G+ G C ++I++C + C + S+ C C G + S+ CQ S C N+ C C G+ G CD D+DEC L + C+H C+N+ GS+ C C + V R ++ N+ S+PCKN C++ +C C PGY G+ CE + +EC + C+ G+C + + C CP G+ CQ + P C NG C D C C G+ G C +++EC PC G C + SF C C+ Y
Sbjct: 30 CLNQGRCEATPDGNGECKCRDGYVGSRCQFHD---PCNNSPCANGGTCRAVSKGNTVDFNCTCKLGFTDRRCMTPINTACF---SSPCRNEGTCEPEGLQGYRCRCPPGLAGEDCSKADPCASNPCANGGRCSLFESFFICTCTPFFSGQTCKQDINECDIQPPLCKNGGLCINEVGGYRCQCPAEY----NGKHCETRYLPCNPSPCLNGGTCIQKGETSYECSCVPGFTGKNCSSN---------------IND------CPGHECQNGGT---------CVDGV-NTYNCQCKPEFTGQLCMDDVDECQLMPNACQNGGTCHNTYGSY--------------------------------------QCVCVNGWTGNDCSKNIDDCADAACYKGSTCHDRVASFYCECPKGRTGLLCQLDDACISNPCQKG-SNCDTNPITGNHFCTCPPGYFGPSCDKDVDECSLGPNPCEHAGKCLNTKGSFQCKCQRGY----VGPRCEMDVNECISNPCKNEATCLDQIGDFQCICMPGYEGEFCEINTDEC----ANGPCLNSGKCIDKINGFHCECPTGFT----GSLCQTDIDECASTP-CKNGAKCTDGPNKYTCECTEGYAGQHCETEINECSS-DPCH--YGTCKDGLASFSCDCTPGYT 596 HSP 7 Score: 85.1149 bits (209), Expect = 3.200e-16 Identity = 130/467 (27.84%), Postives = 192/467 (41.11%), Query Frame = 1
Query: 820 CVKS-RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCL-ELRTC-SKGCQNGGTCFQG----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ-LDNDGKSCIKEECSKFGTTEVV-----------SGN---CKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAIN-CLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECK------------YNHGCEHLCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCN----IECLNGGLCDKDKCKCPPGYIGHNCE-FNDFCHFISPCEHNCT-----TINDNMVCSCLPGYDLMP---DKKTCKKLEC---PKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRC 2031
CV S C C G+ G C P+ + C +G + F+C+C T N C ++ C SK C NGGTC +C C G+ G CQ +N C+ N C G ++C C++G+ L D S E +K ++ +GN C C+ G+ G +C + VDEC CQ C + +G Y C C GF L +N IN C + C G C++ I C C G G C +++D+C +N G CV+ G ++C C SG+ + + +C+S C+ + C+ L + +C+C GY G C+ D C PC + T +C C PG+ D +TC L C C+ G KC CP F G C + + N C + C T + + RC
Sbjct: 963 CVNSYTCTCPAGFSGINCENNTPDCTESS----CFNGGTCVDGINAFTCLCPPGFTGNYCQHDINECDSKPCMNGGTCQDSYGTYKCTCPHGYTGLNCQDLVNWCNSSPCKNGGS---CSQSG-TTYRCNCETGWTGLYCDVPSVSCEVAAKQRGVDITQLCRNAGRCLDAGNVHRCHCQAGYTGSYCEEQVDECTPNPCQNGATCTDFLGGYSCKCLPGF-LGTNCSVEINECFSQPCQNGGTCIDLIDTYKCSCPRGTQGVHCEVNVDDCSPFTDPLTKEPKCFNKG---KCVDRVGGYHCICPSGYVGERCEGDVNECLSNPCDPRGTLSCIQ--LTNNYRCECRAGYTGQRCDTVFDGCKS-RPCRNGGTCAVASNTPHGFICRCPPGFTGSTCEYDSQTCGSLRCRNGGTCISGH-KSPKCLCPPSFTGPECRHPTDSACNSNPCYNGGTCELTPEAPYYRC 1413
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000077889.1 (SMESG000077889.1) HSP 1 Score: 1854.72 bits (4803), Expect = 0.000e+0 Identity = 935/943 (99.15%), Postives = 937/943 (99.36%), Query Frame = 1
Query: 241 MNQVVKIFIIVLINLEFYLIDSFNRNDYFKSGKNQKILSDRNRFFKFDLVQFPVDNNXXXXXXXXXXGYRNFVFTKRKIANSNFQSKNPPPTEYVWDEIGKYWTYKLRHHQSYPDFNFNEFPNSPCKPPFCLPRRCDQIDCGQSNCITNSRPCARNNQDCSMEQKRVLFGSEVVCLNKPAIDNCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGNKGVTKVIEN 3069
MNQVVKIFIIVLINLEFYLIDSFNRNDYFKS KNQKILSDRNRFFKFDLVQFP DNNPTPTPTKTETGYRNFVFTKRKIANSNFQSKNPPPTEYVWDEIGKYWTYKLRHHQSYPDFNFNEFPNSPCKPPFCLPRRCDQIDCGQSNCITNSRPCARNNQDCSMEQKRVLFGSEVVCLNKPAIDNCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCS GQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKK CISKSCNIECLNGGLCDKDKCKCPPGY+GHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGF GLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDC+HGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGY GDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGNKGVTKVIEN
Sbjct: 1 MNQVVKIFIIVLINLEFYLIDSFNRNDYFKSEKNQKILSDRNRFFKFDLVQFPADNNPTPTPTKTETGYRNFVFTKRKIANSNFQSKNPPPTEYVWDEIGKYWTYKLRHHQSYPDFNFNEFPNSPCKPPFCLPRRCDQIDCGQSNCITNSRPCARNNQDCSMEQKRVLFGSEVVCLNKPAIDNCVPDCGEHGICVKSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSSGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKTCISKSCNIECLNGGLCDKDKCKCPPGYVGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFTGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCIHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYKGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHLRYRGRGNKGVTKVIEN 943
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000063217.1 (SMESG000063217.1) HSP 1 Score: 155.606 bits (392), Expect = 5.644e-38 Identity = 211/788 (26.78%), Postives = 325/788 (41.24%), Query Frame = 1
Query: 1024 CQNGGTC--FQGR--CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGF-----QLDNDGKS----CIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECL---FPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI------------------------------------------CYCFSGWHGEDCSL-----DIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCN---IECLNGGLC----DKDKCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENK-----CKCPKGFAGLLCEN------DINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFN----SKCICKSGYRGKRCDEDINECKKYSHICEHF--CMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNN---------KCKCKTGWTGELCDVDIDEC------------LLNQHKCQH-NCVNSNGSYSCS--------CNLPFYLSTVDGRSCLEKNDSCSSPCKNGGKCVNSK----CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
CQNGGTC G CQC + G+ C+ N S C+ + +++ ++C+C + +L N S + +C EV C C +G+ G C++D+DEC P+C+ C+NT+GSYQC C+ GF ++C N+ C G CL+ I C C + W G++C I+ CK N CE + + C C GF K+C + N I C NGG C + KC C PG+ G+NCE N PC++N C +N++ C C G + + C+ G E++ C+C +GF GL CE + C + IC +V NT + C C +G + + + S C + CV+GQC + KCIC G+ G+ C+ +INEC +++ C+H C + Y C C+PGF C+ + C + C N +C+C ++G C +D C N++ H NC + G Y S CNL + G + L ++S PC N +C+N+ CKC Y G CE+ +N C+ ++G C N + C C G+ + C+I + NP C N C D +C C GF G +C ++ ++C + G C + F C+C+ NY+ GT+C +K
Sbjct: 67 CQNGGTCKLIAGNYVCQCLNEWVGEFCEFSSNCASSPCRNGGICKSLEIHK----YECQCPKNYLGMNCELPNSCGSQNPCGVNGKCILANDGEV---KCHCNKGYTGDTCSNDIDECASYETPLCENGGTCINTVGSYQCKCKAGFNGERCENDIVDCTNDTCKNGGTCLDKIGSYRCVCPNNYFGTNCENKRTLCELKPCKNGGICRDFDEDYQCICGNQWTGKNCDDVKNPCKINPCKNNGFCESVNYQ---DYKCICQRGFE----GKRCETSIDNCQKISCFNGGSCINMIEGGKCNCLPGFEGNNCEINVNECENKPCQNNAKCIDLNNDYTCDCPEGLTGKNCEINIDECTPNPCLNGARCEDRVGGFTCQCLQGFVGLRCETKSDICKQLTPCKTEEICLNV-NNTRSGYKCICPDGVQNCKKELS-------KCKNIVCVNGQCVDVNNEEKCICIPGFEGRTCEIEINEC--FNNPCQHGSQCQDLFNDYLCICLPGF----KGKKCEININECAHNPCGLNGQCIDEVYGFRCQCMLPYSGPTCANKLDPCNPNACYNDAICIPGNKYDSYHCNCSTALGRYEGSKCEKDVDECNLDRTQLALYGLALLSMSNSQIGPCLNDNQCINTNGSFICKCSSQYEGRQCEKPLNNCRNDPCRNG--ATCDNLADGFRCRCVAGFT----GERCEIEINECQHNP-CSNDAKCIDHINDYQCICQSGFSGKNCEINDNDCTESSCLG--HGQCVDKVNGFECKCNENYI----GTNCEHLKR 813 HSP 2 Score: 147.132 bits (370), Expect = 2.443e-35 Identity = 183/613 (29.85%), Postives = 261/613 (42.58%), Query Frame = 1
Query: 1486 ICYCFSGWHGEDCSLD----IDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQI--NKKKCISKSCNIECLNGGLCD-----KDKCKCPPGYIGHNCEFNDFCHFISPCEHN--CTTINDNMV-CSCLPGYDL---MPDKKTCKKLECPKCVRG-----TCNENKCKCPKGFAGLLCENDINECLNQTICQH--VCTNTIGSFFCRCKNGHKLA--EDKRS---------------------CIPPNKKTCLDKDCVHGQCF----------------NSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKC-------DFNN--KCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRS--------------CLEKNDSCS-----------------SPCKN----GGKCVN----SKCKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS--RCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSC 2985
+C C G+ G C I C+ C+ + G++ CQC + + + C S C NGG+C K +C+CP Y+G NCE + C +PC N C ND V C C GY D C E P C G T +CKC GF G CENDI +C N T C++ C + IGS+ C C N + E+KR+ CI N+ T + D V C + KCIC+ G+ GKRC+ I+ C+K S C+N KC+C+PGF ++C+ + C+N C D NN C C G TG+ C+++IDEC N C + G ++C C F + +S CL N++ S S CKN G+CV+ KC C PG+ G +CE +INEC +HG +C++ F +Y CIC PG+ K C+I+ + NP LNG ++ RC C + + G C +D C A + I N Y S++C CS+ + Y+G+ C
Sbjct: 44 VCECAYGYKGTYCEQKSNCPITPCQNGGTCKL----IAGNYVCQCLNEWVGEFCEFSSNCASSPCR----NGGICKSLEIHKYECQCPKNYLGMNCELPNSCGSQNPCGVNGKCILANDGEVKCHCNKGYTGDTCSNDIDECASYETPLCENGGTCINTVGSYQCKCKAGFNGERCENDIVDCTNDT-CKNGGTCLDKIGSYRCVCPNNYFGTNCENKRTLCELKPCKNGGICRDFDEDYQCICGNQWTGKNCDDVKNPCKINPCKNNGFCESVNYQDYKCICQRGFEGKRCETSIDNCQKISCFNGGSCINMIEGGKCNCLPGF----EGNNCEINVNECENKPCQNNAKCIDLNNDYTCDCPEGLTGKNCEINIDECTPNPCLNGARCEDRVGGFTCQCLQGFVGLRCETKSDICKQLTPCKTEEICLNVNNTRSGYKCICPDGVQNCKKELSKCKNIVCVNGQCVDVNNEEKCICIPGFEGRTCEIEINECFNNPCQHG--SQCQDLFNDYLCICLPGF----KGKKCEININECAHNPCGLNGQCIDEVYGFRCQCMLPYSGPTCANKLDPCNPNACYNDAICIPGNKYDSYHCNCST-ALGRYEGSKC 636 HSP 3 Score: 142.895 bits (359), Expect = 4.684e-34 Identity = 221/843 (26.22%), Postives = 339/843 (40.21%), Query Frame = 1
Query: 781 IDNCV----PDCGEHGICVKS----RCYCETGWFGERC----VILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC--SKGCQNGGTCF----QGRCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQL---DNDGKSCIKEECSKFGT--TEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQ--QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG----------ICYCFSGWHGEDCSLDIDECKYNHGC--EHLCVNVPGS---FNCQCHSGFTLQINKKKCISKSCNIECLNGGLCD---KDKCKCPPGYIGHNCEFNDFCHFISPCEH--NCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----------KCKCPKGFAGLLCENDI-----NECLNQTICQHVCTNTIGSFFCRCKN------GHKLAEDKRSCIPPNKKTCLDKDCV-------------HGQCFNSK----CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNK---------CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSC-SSPCKNGGKCVNSK---------CKCKPGYNGDSCEEDINECQWPISKHGCIGECRNTFGNYECICPPGYL----VLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCY-----------CPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNY 2958
ID C P C G C+ + +C C+ G+ GERC V + CK G DK + C+C NC RT K C+NGG C +C C + G C N C N C + +++C CQ GF+ + +C K C G+ + G C C G++G C +V+EC CQ C++ Y C C EG L+ C IN ++ C N CLNG C C G+ G C D CK C E +C+NV + + C C G N KK +SK NI C+NG D ++KC C PG+ G CE F +PC+H C + ++ +C CLPG+ K C ++ +C C N +C+C ++G C N + N C N IC + N S+ C C G K +D C + L + QC N+ C C S Y G++C++ +N C+ C N ++C C+ GF C+ + C++ C + K C C++G++G+ C+++ ++C + CV+ + C CN + G +C C S+PC N G C+N K C C+ G+ G CE ++ C+ + G G C +++C C Y+ + +TC+ + N +N +C+ C+ C G+ G C V++D+C PC G C + G ++C+C +
Sbjct: 174 IDECASYETPLCENGGTCINTVGSYQCKCKAGFNGERCENDIVDCTNDTCKN-------GGTCLDKIG-SYRCVCPNNYFGTNCENKRTLCELKPCKNGGICRDFDEDYQCICGNQWTGKNCDDVKNPCKINPCKNNG---FCESVNYQDYKCICQRGFEGKRCETSIDNCQKISCFNGGSCINMIEGGKCNCLPGFEGNNCEINVNECENKPCQNNAKCIDLNNDYTCDCPEG---LTGKNCEIN-IDECTPN-PCLNGARCEDRVGGFTCQCLQGFVGLRCETKSDICKQLTPCKTEEICLNVNNTRSGYKCICPDGVQ---NCKKELSKCKNIVCVNGQCVDVNNEEKCICIPGFEGRTCEIEINECFNNPCQHGSQCQDLFNDYLCICLPGF----KGKKC-EININECAHNPCGLNGQCIDEVYGFRCQCMLPYSGPTCANKLDPCNPNACYNDAIC--IPGNKYDSYHCNCSTALGRYEGSKCEKDVDECNLDRTQLALYGLALLSMSNSQIGPCLNDNQCINTNGSFICKCSSQYEGRQCEKPLNNCRNDPCRNGATCDNLADGFRCRCVAGFT----GERCEIEINECQHNPCSNDAKCIDHINDYQCICQSGFSGKNCEINDNDCTESSCLGHGQCVDKVNGFECKCNENYI-----GTNCEHLKRPCDSNPCLNKGSCINRKVNQNTPGYLCNCRRGFTGPRCEIKMDWCRG--NPCGDFGVCETDLDSFKCKCNSEYIGERCEIKKTETCKSYAVEKFKNESLIN-KICKHHGNCFNDPETGGFKCSCQSGYGGSFCEVNIDDCAS-QPCIN-GGECGDGTGMYFCKCQPGF 976 HSP 4 Score: 126.716 bits (317), Expect = 4.388e-29 Identity = 214/748 (28.61%), Postives = 304/748 (40.64%), Query Frame = 1
Query: 1057 CQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQ---SGFQLDNDGKSCIKEECSKFGTTEVVSGN------CKCKQG---WKGKFCNDDVDECLFPVCQ--------------QI--------CVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGI----------CYCFSGWHGEDCSLDIDECKYNH-GCEHLCVNVPGSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLC-DKD---KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQH-VCTNTIGSFFCRCKNGH-------KLAEDKRSCIPPNKK--TCLDKDCVH-GQCFNS------KCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFIL---SANSHSCQSVCSLCKNGKC--DFNN-KCKCKTGWTGELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS---------------SPCKNGG--KCVNS----KCKCKPGYNGDSCEEDINECQ-------WPISKHG-CIGECRNTFG---NYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMS-------RCYCPIGFHGIDCGVD-VDECQRYAPCDKLRGICYNTYGSFYCQCS 2949
C C GF+G +C++ IN C+ G C++E F+C+C SG N C C + + GN C C ++G C DVDEC Q QI C+NT GS+ C C + G+ LNNC +N C NG C C +G+ GE C ++I+EC++N + C++ + C C SGF+ +IN C SC L G C DK +CKC YIG NCE H PC+ N CL +K +C + + G C C +GF G CE ++ C VC + SF C+C + + K E +S K + ++K C H G CFN KC C+SGY G C+ +I++C I C + G Y C C PGF N++ C S + C GKC NN C C G +G C+ +D C + +CQ+ C N G + C+C F G+ C + C PC G +C++ C CK + G CE I+ C+ P +G C+ + +N G N+ CICP GY + C+I++K N C N G+CR +C CP G G+ C +D V+EC + G C N +G C C+
Sbjct: 544 CICLPGFKGKKCEININECAHNPCG---LNGQCIDEVYG-FRCQCMLPYSGPTCANKLDPCNPNAC--YNDAICIPGNKYDSYHCNCSTALGRYEGSKCEKDVDECNLDRTQLALYGLALLSMSNSQIGPCLNDNQCINTNGSFICKCSSQYE----GRQCEKPLNNC-RNDPCRNGATCDNLADGFRCRCVAGFTGERCEIEINECQHNPCSNDAKCIDHINDYQCICQSGFSGKNCEINDNDCTESSC----LGHGQCVDKVNGFECKCNENYIGTNCE-----HLKRPCDSN----------PCL-------NKGSCINRKVNQNTPGYL----CNCRRGFTGPRCEIKMDWCRGNPCGDFGVCETDLDSFKCKCNSEYIGERCEIKKTETCKSYAVEKFKNESLINKICKHHGNCFNDPETGGFKCSCQSGYGGSFCEVNIDDCASQPCINGGECGDGTGMYFCKCQPGFQGVNCQVNTNECYS--NSCNTGKCIDQINNFSCVCPRGVSGRFCETIVDYC--KKMECQNGGICKNVIGDFECNCPKGFA-----GKLCETDINECKYNIAGNATNLISNPHGPCSPTGTLECLDRPGTFHCSCKKYFTGKYCETRIDYCEKFRKSGNIPCFNNGICLNKYQNEVGRNYNFSCICPNGY----GGERCKINSKKCQLNV-CKNNGICRPFEIDDRMSFKCECPPGVGGLFCEIDYVNECLSTKCYN--NGSCVNGFGKAICHCN 1234 HSP 5 Score: 112.849 bits (281), Expect = 9.339e-25 Identity = 177/600 (29.50%), Postives = 241/600 (40.17%), Query Frame = 1
Query: 1024 CQNGGTCFQ----GRCQCTEGFEGDQCQLEINSCSRGQMGNRT--CEHICVNEGENNFQCKCQSGFQLDN---DGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCND-----DVDECLFP---VCQQICVNTIGSYQCSCREGFTLLSNGKCAINC----LNNCNKNGDCLNGI----CYCFSGWHGEDCSLDIDE-CK------------YNHGCEHL--CVNVP--GSFNCQCHSGFTL---QINKKKCISKSCNIECLNGGLCDKDK----CKCPPGYIGHNCEFN-DFCHFISPCEHNCTTINDNMVCSCLPGY-----DLMPDKKTCKKLECPK--CVRGTCNENKCKCPKGFAGLLCENDINECLNQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNKCKCKTGWTGELCDVDIDECLLNQHK----CQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEK--NDSCSSPCKNGGKCVN----SKCKCKPGYNGDSCE 2616
C+NG TC RC+C GF G++C++EIN C N +HI N++QC CQSGF N + C + C G +V CKC + + G C D + CL + +++ NT G Y C+CR GFT +C I N C G C + C C S + GE C + E CK N C+H C N P G F C C SG+ ++N C S+ C +NGG C CKC PG+ G NC+ N + C+ S C +N C C G + + D CKK+EC + + +C CPKGFAG LCE DINEC N G+ N H C P CLD+ C CK + GK C+ I+ C+K+ C N G L+ + ++N C C G+ GE C ++ +C LN K C+ ++ S+ C C V G C N+ S+ C N G CVN + C C G G+ CE
Sbjct: 706 CRNGATCDNLADGFRCRCVAGFTGERCEIEINECQHNPCSNDAKCIDHI------NDYQCICQSGFSGKNCEINDNDCTESSCLGHGQCVDKVNGFECKCNENYIGTNCEHLKRPCDSNPCLNKGSCINRKVNQNTPG-YLCNCRRGFT---GPRCEIKMDWCRGNPCGDFGVCETDLDSFKCKCNSEYIGERCEIKKTETCKSYAVEKFKNESLINKICKHHGNCFNDPETGGFKCSCQSGYGGSFCEVNIDDCASQPC----INGGECGDGTGMYFCKCQPGFQGVNCQVNTNECYSNSCNTGKCIDQINNFSCVCPRGVSGRFCETIVD--YCKKMECQNGGICKNVIGDFECNCPKGFAGKLCETDINECK---------YNIAGNATNLISNPHG------PCSPTGTLECLDRPGTF------HCSCKKYFTGKYCETRIDYCEKFRKSGNIPCFNN----------GICLNKYQNEVGR----------NYNFSCICPNGYGGERCKINSKKCQLNVCKNNGICRPFEIDDRMSFKCEC-----PPGVGGLFCEIDYVNECLSTKCYNNGSCVNGFGKAICHCNKGSCGEKCE 1243
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000027402.1 (SMESG000027402.1) HSP 1 Score: 127.487 bits (319), Expect = 2.045e-29 Identity = 199/689 (28.88%), Postives = 279/689 (40.49%), Query Frame = 1
Query: 1276 GNCKCKQGWKGKFCNDDVDECL-FPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG-------------ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKD-----KCKCPPGYIGHNCEF-----NDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTC----------NENKCKCPKGFAGLLCENDI----NECLNQTICQHVCTNTIGSFFCRCKNGHKLA--EDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNK----CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRS-------------CLEKNDSC--------------------------SSPCKNGGKCVNS------KCKCKPGYNGDSCEEDINECQWPISKHGCIGE--CRNT-FGNYECICPPGYLVLDDQKTCQISTKDTMCNPH-CLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMK--EAVLKPHLRYRGR 3036
G C+C+ GW+G FC DEC+ +P C+ CV++ + CSC + G+ LN C +N C NG C C SG+ G DC +ID C N + C+ G F CQC +T ++ + C SC NGG C KD +C C GY G C N C C+ T + D C C PGY K C K E +CV C N+ KC C F G CE +I C N +CQ V T + C+CK G+ E ++ PN CL+ + + C C + GKRC+ C S E +Y MP + S+ + C K G C + K C+C G+ G+ C++DID+C N K C++S ++ C C+ F+ T + R+ CL +D S+PC NGG C +C C G+ G C+ + Q K+ C E C N + ++ C C PG+ + K C I+T + CNP+ C NGG C D RC C GF+G +C ++ DEC + PC IC + F C+C DG C +K E+ P Y R
Sbjct: 241 GECRCRAGWQGTFC----DECMKYPGCKHGTCVDS--PWTCSCENNW----GGQFCDQSLNYCAENNPCKNGGICENLLSEVQPYKCICPSGFEGRDC--EIDPCFPNPCKKGTCMKSKGEFYCQCIERWTGKLCDQDTSICDQNSCQ----NGGQCGKDENGNRRCICQQGYKGSECHLAAPCENSQCKHALDCQIQSTALGD-YKCLCQPGYT----GKYCDK-EINECVPNPCKNNGVCTDSINDYKCNCSTSFKGKNCELNIACQNQPCKNGGVCQEVDT----GYTCKCKTGYTGTNCEIYKTGCSPNP--CLNGAYCYTINQDFYCHCNKEFWGKRCEHSRPYCGNES---------CESAYDACSMPQMLNSSGIK--HNYCG--KYGTCLSHEKEKFICRCMPGFEGDSCEIDIDDCKTNPCKNGGICIDSINNFECICDNGFFGKTCEERTDYCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLCHLPKHSICDSNPCLNGGSCSRLSTLNGFQCHCNQGWIGTVCQFLHIDFQPCRRKNLCKNEGVCINVGYNDFTCHCKPGF----EGKHCDINTNE--CNPNPCFNGGKCIDKLNSYRCICAKGFYGSNCQLNYDECASF-PC-AYGAICVDRIDDFECRCPEG----RDGKLCDHVKNNESPQPPSCVYYNR 876 HSP 2 Score: 98.2117 bits (243), Expect = 1.884e-20 Identity = 193/694 (27.81%), Postives = 282/694 (40.63%), Query Frame = 1
Query: 790 CVPDCGE-HGICV-KSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLE-LRTCSKG--CQNGGTCFQ-------GRCQCTEGFEGDQCQLEI---NSCSRGQMGNRTCEHICVNEGENNFQCKC---QSGFQLDNDGKSCIKEECS---KFGTTEVVSGNCKCKQGWKGKFCNDDV----DECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFT---LQINKKKCISKSCNIECLNGGLC---DKD-KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDL--MPDKKTCKKLECPKCVR-GTCNENK-----CKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGH--KLAEDKRSCIPPNKKTCLDKDCV-HGQCFNSK--------CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVC-------------SLCKN-------GKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEE 2619
C P C HG C C C GW G C + C K C HG D ++C C C + L C++ C+NGG C +C C GFEG C+++ N C +G TC + + F C+C +G D D C + C + G E + C C+QG+KG C+ +C + QI +G Y+C C+ G+T K C+ N C NG C + I C C + + G++C L+I C+ N C++ +C V + C+C +G+T +I K C C LNG C ++D C C + G CE H C + SC YD MP ++ C + GTC ++ C+C GF G CE DI++C N +C ++I +F C C NG K E++ C+ C+ +G C C CK+ + G+ C K+S + C+N + S + GF N +VC +LCKN G DF C CK G+ G+ CD++ +EC N C++ SY C C FY G +C D C+S PC G CV+ +C+C G +G C+
Sbjct: 226 CQPGCHRIHGYCENPGECRCRAGWQGTFC-----DEC--MKYPGCKHGTCVDS---PWTCSCENNWGGQFCDQSLNYCAENNPCKNGGICENLLSEVQPYKCICPSGFEGRDCEIDPCFPNPCKKG-----TCM-----KSKGEFYCQCIERWTGKLCDQDTSICDQNSCQNGGQCGKDENGNRRCICQQGYKGSECHLAAPCENSQCKHALDCQIQSTALGDYKCLCQPGYTGKYCDKEINECVPNPCKNNGVCTDSINDYKCNCSTSFKGKNCELNI-ACQ-NQPCKNGGVCQEVDTGYTCKCKTGYTGTNCEIYKTGCSPNPC----LNGAYCYTINQDFYCHCNKEFWGKRCE-----HSRPYCGNE----------SCESAYDACSMPQMLNSSGIKHNYCGKYGTCLSHEKEKFICRCMPGFEGDSCEIDIDDCKTNPCKNGGICIDSINNFECICDNGFFGKTCEERTD-------YCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLC-----HLPKHSICDSNPCLNGGSCSRLSTLNGFQCHCNQGWIGTVCQFLHIDFQPCRRKNLCKNEGVCINVGYNDFT--CHCKPGFEGKHCDINTNECNPNPCFNGGKCIDKLNSYRCICAKGFY-----GSNCQLNYDECASFPCAYGAICVDRIDDFECRCPEGRDGKLCDH 859 HSP 3 Score: 73.9442 bits (180), Expect = 5.594e-13 Identity = 154/622 (24.76%), Postives = 234/622 (37.62%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKSR----CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQG-----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGI-----CYCFSGWHGEDCSLDIDECKYNHGCE-------HLCVNVPGSFNCQCHSGF---TLQINKKKCISKSCNIE-------------------CLNGGLC-----DKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKK-----LECPKCVRGTC--------NENKCKCPKGFAGLLCEN------DINECLNQTICQHVCTNTIGSFFCRCKNG------HKLAEDKRSCIPPNKKTCLDKD-CVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILS---ANSHSCQSV----CSLCKNGKCDFNNKCKCKTGWTGELCD 2388
ID C P+ + G C+KS+ C C W G+ C + +C Q CQNGG C + RC C +G++G +C L N C+H C+ QS T + C C+ G+ GK+C+ +++EC+ C+ +C ++I Y+C+C F N + I C N KNG + C C +G+ G +C + Y GC C + F C C+ F + ++ C ++SC C G C +K C+C PG+ G +CE + D C +PC++ I+ +N C C G+ KTC++ ++ P G C N+ C+C + G LC D N CLN C + +T+ F C C G L D + C K C ++ C++ + C CK G+ GK CD + NEC C++ SY+C C GF S N C S ++C + DF +C+C G G+LCD
Sbjct: 330 IDPCFPNPCKKGTCMKSKGEFYCQCIERWTGKLCD-QDTSICDQN---------------------------------------SCQNGGQCGKDENGNRRCICQQGYKGSECHLA------APCENSQCKHA--------LDCQIQS---------------------TALGDYKCLCQPGYTGKYCDKEINECVPNPCKNNGVCTDSINDYKCNCSTSFK-GKNCELNIACQNQPCKNGGVCQEVDTGYTCKCKTGYTGTNCEI------YKTGCSPNPCLNGAYCYTINQDFYCHCNKEFWGKRCEHSRPYCGNESCESAYDACSMPQMLNSSGIKHNYCGKYGTCLSHEKEKFICRCMPGFEGDSCEIDIDDCK-TNPCKNGGICIDSINNFECICDNGF----FGKTCEERTDYCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLCHLPKHSICDSNPCLNGGSCSRL--STLNGFQCHCNQGWIGTVCQFLHIDFQPC--RRKNLCKNEGVCINVGYNDFTCHCKPGFEGKHCDINTNECNPNPCFNGGKCIDKLNSYRCICAKGFYGSNCQLNYDECASFPCAYGAICVDRIDDF--ECRCPEGRDGKLCD 858 HSP 4 Score: 53.9138 bits (128), Expect = 8.342e-7 Identity = 97/357 (27.17%), Postives = 144/357 (40.34%), Query Frame = 1
Query: 781 IDNCVPD-CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC---SKGCQNGGTCFQ------GRCQCTEGFEGDQCQ---LEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ---LDNDGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDECL-FP-VCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNI-ECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPC 1776
ID+C + C GIC+ S C C+ G+FG+ C K + + V D+ DF C C C + S C NGG+C + +C C +G+ G CQ ++ C R + E +C+N G N+F C C+ GF+ D + C C G ++ S C C +G+ G C + DEC FP ICV+ I ++C C EG +GK + NN ++ + + Y GE +++ C+ NC C G K C S C + CL D D C PG + ++ FN F+ PC
Sbjct: 621 IDDCKTNPCKNGGICIDSINNFECICDNGFFGKTCEERTDYCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLCHLPKHSICDSNPCLNGGSCSRLSTLNGFQCHCNQGWIGTVCQFLHIDFQPCRRKNLCKN--EGVCINVGYNDFTCHCKPGFEGKHCDINTNECNPNPCFNGGKCIDKLNSYRCICAKGFYGSNCQLNYDECASFPCAYGAICVDRIDDFECRCPEG----RDGKLCDHVKNN--ESPQPPSCVYYNRIFDSGE---------TWSYNCQ----------NCACDRG------KVTCESVPCGVWTCLQANGTD-DPYACKPGEMCYSFPFNPKRCFVPPC 943
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000027402.1 (SMESG000027402.1) HSP 1 Score: 127.487 bits (319), Expect = 2.200e-29 Identity = 199/689 (28.88%), Postives = 279/689 (40.49%), Query Frame = 1
Query: 1276 GNCKCKQGWKGKFCNDDVDECL-FPVCQQ-ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNG-------------ICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQI---NKKKCISKSCNIECLNGGLCDKD-----KCKCPPGYIGHNCEF-----NDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTC----------NENKCKCPKGFAGLLCENDI----NECLNQTICQHVCTNTIGSFFCRCKNGHKLA--EDKRSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFNNK----CKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRS-------------CLEKNDSC--------------------------SSPCKNGGKCVNS------KCKCKPGYNGDSCEEDINECQWPISKHGCIGE--CRNT-FGNYECICPPGYLVLDDQKTCQISTKDTMCNPH-CLNGGVCRDM---SRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMK--EAVLKPHLRYRGR 3036
G C+C+ GW+G FC DEC+ +P C+ CV++ + CSC + G+ LN C +N C NG C C SG+ G DC +ID C N + C+ G F CQC +T ++ + C SC NGG C KD +C C GY G C N C C+ T + D C C PGY K C K E +CV C N+ KC C F G CE +I C N +CQ V T + C+CK G+ E ++ PN CL+ + + C C + GKRC+ C S E +Y MP + S+ + C K G C + K C+C G+ G+ C++DID+C N K C++S ++ C C+ F+ T + R+ CL +D S+PC NGG C +C C G+ G C+ + Q K+ C E C N + ++ C C PG+ + K C I+T + CNP+ C NGG C D RC C GF+G +C ++ DEC + PC IC + F C+C DG C +K E+ P Y R
Sbjct: 248 GECRCRAGWQGTFC----DECMKYPGCKHGTCVDS--PWTCSCENNW----GGQFCDQSLNYCAENNPCKNGGICENLLSEVQPYKCICPSGFEGRDC--EIDPCFPNPCKKGTCMKSKGEFYCQCIERWTGKLCDQDTSICDQNSCQ----NGGQCGKDENGNRRCICQQGYKGSECHLAAPCENSQCKHALDCQIQSTALGD-YKCLCQPGYT----GKYCDK-EINECVPNPCKNNGVCTDSINDYKCNCSTSFKGKNCELNIACQNQPCKNGGVCQEVDT----GYTCKCKTGYTGTNCEIYKTGCSPN--PCLNGAYCYTINQDFYCHCNKEFWGKRCEHSRPYCGNES---------CESAYDACSMPQMLNSSGIK--HNYCG--KYGTCLSHEKEKFICRCMPGFEGDSCEIDIDDCKTNPCKNGGICIDSINNFECICDNGFFGKTCEERTDYCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLCHLPKHSICDSNPCLNGGSCSRLSTLNGFQCHCNQGWIGTVCQFLHIDFQPCRRKNLCKNEGVCINVGYNDFTCHCKPGF----EGKHCDINTNE--CNPNPCFNGGKCIDKLNSYRCICAKGFYGSNCQLNYDECASF-PC-AYGAICVDRIDDFECRCPEG----RDGKLCDHVKNNESPQPPSCVYYNR 883 HSP 2 Score: 98.2117 bits (243), Expect = 1.972e-20 Identity = 193/694 (27.81%), Postives = 282/694 (40.63%), Query Frame = 1
Query: 790 CVPDCGE-HGICV-KSRCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLE-LRTCSKG--CQNGGTCFQ-------GRCQCTEGFEGDQCQLEI---NSCSRGQMGNRTCEHICVNEGENNFQCKC---QSGFQLDNDGKSCIKEECS---KFGTTEVVSGNCKCKQGWKGKFCNDDV----DECLFPVCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNN-CNKNGDCLNGI----CYCFSGWHGEDCSLDIDECKYNHGCEH--LCVNVPGSFNCQCHSGFT---LQINKKKCISKSCNIECLNGGLC---DKD-KCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDL--MPDKKTCKKLECPKCVR-GTCNENK-----CKCPKGFAGLLCENDINEC-LNQTICQHVCTNTIGSFFCRCKNGH--KLAEDKRSCIPPNKKTCLDKDCV-HGQCFNSK--------CICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILSANSHSCQSVC-------------SLCKN-------GKCDFNNKCKCKTGWTGELCDVDIDECLLNQHKCQHNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSS-PCKNGGKCVNS----KCKCKPGYNGDSCEE 2619
C P C HG C C C GW G C + C K C HG D ++C C C + L C++ C+NGG C +C C GFEG C+++ N C +G TC + + F C+C +G D D C + C + G E + C C+QG+KG C+ +C + QI +G Y+C C+ G+T K C+ N C NG C + I C C + + G++C L+I C+ N C++ +C V + C+C +G+T +I K C C LNG C ++D C C + G CE H C + SC YD MP ++ C + GTC ++ C+C GF G CE DI++C N +C ++I +F C C NG K E++ C+ C+ +G C C CK+ + G+ C K+S + C+N + S + GF N +VC +LCKN G DF C CK G+ G+ CD++ +EC N C++ SY C C FY G +C D C+S PC G CV+ +C+C G +G C+
Sbjct: 233 CQPGCHRIHGYCENPGECRCRAGWQGTFC-----DEC--MKYPGCKHGTCVDS---PWTCSCENNWGGQFCDQSLNYCAENNPCKNGGICENLLSEVQPYKCICPSGFEGRDCEIDPCFPNPCKKG-----TCM-----KSKGEFYCQCIERWTGKLCDQDTSICDQNSCQNGGQCGKDENGNRRCICQQGYKGSECHLAAPCENSQCKHALDCQIQSTALGDYKCLCQPGYTGKYCDKEINECVPNPCKNNGVCTDSINDYKCNCSTSFKGKNCELNI-ACQ-NQPCKNGGVCQEVDTGYTCKCKTGYTGTNCEIYKTGCSPNPC----LNGAYCYTINQDFYCHCNKEFWGKRCE-----HSRPYCGNE----------SCESAYDACSMPQMLNSSGIKHNYCGKYGTCLSHEKEKFICRCMPGFEGDSCEIDIDDCKTNPCKNGGICIDSINNFECICDNGFFGKTCEERTD-------YCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLC-----HLPKHSICDSNPCLNGGSCSRLSTLNGFQCHCNQGWIGTVCQFLHIDFQPCRRKNLCKNEGVCINVGYNDFT--CHCKPGFEGKHCDINTNECNPNPCFNGGKCIDKLNSYRCICAKGFY-----GSNCQLNYDECASFPCAYGAICVDRIDDFECRCPEGRDGKLCDH 866 HSP 3 Score: 73.9442 bits (180), Expect = 5.898e-13 Identity = 154/622 (24.76%), Postives = 234/622 (37.62%), Query Frame = 1
Query: 781 IDNCVPDCGEHGICVKSR----CYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTCFQG-----RCQCTEGFEGDQCQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQ--ICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGI-----CYCFSGWHGEDCSLDIDECKYNHGCE-------HLCVNVPGSFNCQCHSGF---TLQINKKKCISKSCNIE-------------------CLNGGLC-----DKDKCKCPPGYIGHNCEFN-DFCHFISPCEHNCTTIN--DNMVCSCLPGYDLMPDKKTCKK-----LECPKCVRGTC--------NENKCKCPKGFAGLLCEN------DINECLNQTICQHVCTNTIGSFFCRCKNG------HKLAEDKRSCIPPNKKTCLDKD-CVHGQCFNSKCICKSGYRGKRCDEDINECKKYSHICEHFCMNTEGSYKCSCMPGFILS---ANSHSCQSV----CSLCKNGKCDFNNKCKCKTGWTGELCD 2388
ID C P+ + G C+KS+ C C W G+ C + +C Q CQNGG C + RC C +G++G +C L N C+H C+ QS T + C C+ G+ GK+C+ +++EC+ C+ +C ++I Y+C+C F N + I C N KNG + C C +G+ G +C + Y GC C + F C C+ F + ++ C ++SC C G C +K C+C PG+ G +CE + D C +PC++ I+ +N C C G+ KTC++ ++ P G C N+ C+C + G LC D N CLN C + +T+ F C C G L D + C K C ++ C++ + C CK G+ GK CD + NEC C++ SY+C C GF S N C S ++C + DF +C+C G G+LCD
Sbjct: 337 IDPCFPNPCKKGTCMKSKGEFYCQCIERWTGKLCD-QDTSICDQN---------------------------------------SCQNGGQCGKDENGNRRCICQQGYKGSECHLA------APCENSQCKHA--------LDCQIQS---------------------TALGDYKCLCQPGYTGKYCDKEINECVPNPCKNNGVCTDSINDYKCNCSTSFK-GKNCELNIACQNQPCKNGGVCQEVDTGYTCKCKTGYTGTNCEI------YKTGCSPNPCLNGAYCYTINQDFYCHCNKEFWGKRCEHSRPYCGNESCESAYDACSMPQMLNSSGIKHNYCGKYGTCLSHEKEKFICRCMPGFEGDSCEIDIDDCK-TNPCKNGGICIDSINNFECICDNGF----FGKTCEERTDYCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLCHLPKHSICDSNPCLNGGSCSRL--STLNGFQCHCNQGWIGTVCQFLHIDFQPC--RRKNLCKNEGVCINVGYNDFTCHCKPGFEGKHCDINTNECNPNPCFNGGKCIDKLNSYRCICAKGFYGSNCQLNYDECASFPCAYGAICVDRIDDF--ECRCPEGRDGKLCD 865 HSP 4 Score: 53.5286 bits (127), Expect = 9.168e-7 Identity = 97/357 (27.17%), Postives = 144/357 (40.34%), Query Frame = 1
Query: 781 IDNCVPD-CGEHGICVKS----RCYCETGWFGERCVILEPELCKQRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTC---SKGCQNGGTCFQ------GRCQCTEGFEGDQCQ---LEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQ---LDNDGKSCIKEECSKFG--TTEVVSGNCKCKQGWKGKFCNDDVDECL-FP-VCQQICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGDCLNGICYCFSGWHGEDCSLDIDECKYNHGCEHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNI-ECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPC 1776
ID+C + C GIC+ S C C+ G+FG+ C K + + V D+ DF C C C + S C NGG+C + +C C +G+ G CQ ++ C R + E +C+N G N+F C C+ GF+ D + C C G ++ S C C +G+ G C + DEC FP ICV+ I ++C C EG +GK + NN ++ + + Y GE +++ C+ NC C G K C S C + CL D D C PG + ++ FN F+ PC
Sbjct: 628 IDDCKTNPCKNGGICIDSINNFECICDNGFFGKTCEERTDYCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLCHLPKHSICDSNPCLNGGSCSRLSTLNGFQCHCNQGWIGTVCQFLHIDFQPCRRKNLCKN--EGVCINVGYNDFTCHCKPGFEGKHCDINTNECNPNPCFNGGKCIDKLNSYRCICAKGFYGSNCQLNYDECASFPCAYGAICVDRIDDFECRCPEG----RDGKLCDHVKNN--ESPQPPSCVYYNRIFDSGE---------TWSYNCQ----------NCACDRG------KVTCESVPCGVWTCLQANGTD-DPYACKPGEMCYSFPFNPKRCFVPPC 950
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000076582.1 (SMESG000076582.1) HSP 1 Score: 124.02 bits (310), Expect = 4.197e-28 Identity = 227/761 (29.83%), Postives = 316/761 (41.52%), Query Frame = 1
Query: 1021 GCQNGGTCFQGRCQCTEGFEGDQCQLEINSCSRGQMG-NRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTL-LSNGKCAINCLNNCNKN----GD---CLNGI----CYCFSG--WHGEDCSLDIDECKY-NHGCEHL--CVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEH-NCTT---INDNMVCSCLPGYDLMPDKKTC--KKLECPKCVRGTCNENK--CKCPKGFAG---LLCENDINEC--------LNQTICQHV--CTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCL---DKDCVHGQ-CFNSK----CICKSGYR---GKRCDEDINECKKYSHICE--HFCMNTEGSYKCSCMPGFILS-------------ANSHSCQSVC-SLCKNGKCDFNNKCKCKTGWT--GELCDVDIDECLLNQHKCQHN--CVNSNGSYSCSC-NLPFYLSTVD---GRSCLEKNDSCSSPCKNGGKC----VNSKCKCKPGYNGDSCE----EDINECQWPISKHGCIG---ECRNTFGNYECICPPGYLVLDD-----QKTCQISTKDTMCNPHCLNGGVCRDMS---RCYCPIGF--HGIDCGVDVDECQR------YAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
GC N F C + E + I+SC+ G +R E C++ ++++ C+C GFQ N SC+ + C D +D C C N IGSY C C + L LS C N C +N GD CLN C C +G W+G +C DIDEC H C L C NVPGS C+C GFT + SC +D KCP G +C+ I + NCT ++ M C Y D C +K C K T N+ C CP G CE D NEC LN + C+++ N + F C C NG+ + C+ NK CL + DCV C +++ C CKSG++ +C E+INEC++ S C C + + C C PGF S N SC S+ S+C N F +C C G++ G C+ DI+ECL+ + C N C N+ ++CSC N L D CLE D C C + C C G+ D E+ NEC+ I+ H C EC +T+G+++C+C PG+ D C+IS + M N G C + + C CP GF + DC +DVDEC CD++ G C NT G F C C+ +V++ + T C+ + E
Sbjct: 4596 GCLNTKGSFVCTCNQEQMNENNSSCKPIDSCAMGLDNCDRKVED-CISSKDSSYTCQCIEGFQRIN--GSCVDVD-----------------------ECADKIDSCKN---NATCNNMIGSYVCKCPDNLKLDLSKKACTDR--NECQENPMICGDLSKCLNTDGSYECQCVTGYKWNGTNCE-DIDECAIKTHPCHDLARCSNVPGSCKCKCQPGFTGDGIYSCIETDSCPA---------RDDVKCPTG---------SYCNMIGNFIYCNCTNGYEDSNQMECIGDVCYKKCSDIDECVTRKSACHKFAECTNNDGAYVCTCPSYLTGDGKTTCE-DQNECALETHTCNLNTSYCENLDNTVNVLAPFQCHCFNGYVKIPGTQICL--NKNECLNPVENDCVENAICIDTEGSYECRCKSGFKQLPSGKC-ENINECEEKSDNCSINSVCQDKADGFSCQCKPGFKWSDETNLNCEDIDECTNPTSCSSMPHSICMNNPGSF--ECVCPHGFSLQGGYCN-DINECLI-PNSCGQNSVCANTVSGFNCSCANGARQLPNGDCELINECLENIDRCQVLNGADSVCYDLPIGYACVCPDGFVNDEVFPQVCENQNECE--INIHSCQASNSECVDTYGSFKCVCKPGFSKNSDGDCVDYDECEISEQSNM---KFCNNGKCINTAGGFTCDCPEGFIYNNYDC-IDVDECSLDQVSSLADNCDQVNGHCINTVGGFQCYCNRGFVMIENSTKCVDIDE 5292 HSP 2 Score: 117.472 bits (293), Expect = 3.686e-26 Identity = 220/821 (26.80%), Postives = 331/821 (40.32%), Query Frame = 1
Query: 814 GICVKSRCYCETGWFGERCVILEPELCK--QRKLLFCVHGCSFDKRKLDFSCICGIKETQNNCLELRTCSKGCQNGGTC-FQGR---CQCTEGFEGDQCQ-LEINSCSRGQM---GNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIK-EECSKFG----TTE-----VVSGNCKCKQGWKGKFCN---DDVDECLFP--VCQQI---CVNTIGSYQCSCREGF------TLLSNGKCAINCLNNCNKN-GDCLNG----ICYCFSGWHGEDCS-LDIDECKYNHGCEH---LCVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCE----------HNCTTINDNMVCSCLPGYDLMPDKKTCKKL-ECPKCVRGTCNENK----------CKCPKGFAGLLCE-NDINECL----NQTICQHVCTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCV--HGQCFNS----KCICKSGYRGKRCDE--DINECKKYSHICE--HFCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNGKCDFN-----NKCKCKTGWTGELCD-VDIDECLLNQHKCQ--HNCVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCSSPCK-----NGGKCVNSKCKCKPGYNGDSCEEDINECQWPISKHGCIGE-CRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMY-DGTSCMTM 2994
G CV+S C C G+ E +PE C + +G C C + Q C + C N C F+ C C GF GD +I+ CS N C++ +F C C+ GF+ +G +C EC TE V C+C++G+ DD +EC +C ++ C NT GSY+C C+ GF + + N ++ C+KN C N C C SG+ G+ + DIDEC N C+ CVN+PGS+ C+C G C + C +C +C C G+ N + C I C+ C ++ + C CL GY + K C+ + EC + C EN C+C GF G E DI+EC N + C N+IGSF CRC G+ + D C ++ +C H CFN +C C SGY+ D NEC+ + + C+ C+NT+GS+ C C G+I S + Q C C N + C CK+G+ ++ DEC +Q C NC++++GS+ C CN + DG +C +K D+ + C+ G C + C C G+ + C E C N +CP + C IS+ +C+ + + D S+C +D+DEC + IC+N +GS+ C+C NY+ ++ DG CM +
Sbjct: 3111 GQCVES-CICAPGYVLENGNCTKPEACGCLMSDGTYYANGEQRTNENCSVKCRCKGETGQLECTNIT-----CSNDAFCDFKDDDYGCHCKNGFMGDGIMCKDIDECSNNTSVCDSNAFCKNTI-----GSFSCSCKEGFE--GNGVTCTNINECYPLSPCDNATEECFDKVPGYECRCQKGFMKNTTTGNCDDRNECADTGNLCDRVSTNCNNTFGSYRCDCKYGFRPSPIDSFVCTDVNECNLVHECDKNYAKCTNTPGSYYCTCDSGYQGDGRNCTDIDECSSNKVCQRPDATCVNLPGSYECRCLDGTPGCDGDNPCNTVQCTKP---NEICYLGQCFCKHGF--QNNVTTNICEDIDECDTAANDCAGRKAKCANLDGSYECECLYGYRMSSINKICENINECIDNLH-QCGENAECIDTDGGYYCQCKTGFTGHCDECRDIDECAFSLNNCDSDRATCENSIGSFTCRCNEGY--SGDGSVCSEIDECLLGLHNCSRSHQFCFNVNGGFECRCLSGYKSDTNGSCVDENECRFFDNGCDDNADCINTDGSFLCICRAGYIGSGRNCDPQEGLEECGKLLCPLNALCVNSTCLCKSGYENSTNQCINTDECE-SQTSCDVNANCIDTHGSFICYCNEGY---IGDGINCFKK-DTDTDACQIENYCTDGDCYDGICHCPSGF--------------VFKSNKCFDERCEN-------VCPKNAI-------CSISSGSPVCSCS-VGTSLSSDSSQC------------IDIDECNENVDDCQENSICFNRFGSYDCKCPPNYLDVFKDGKVCMAV 3864 HSP 3 Score: 102.064 bits (253), Expect = 1.950e-21 Identity = 172/590 (29.15%), Postives = 240/590 (40.68%), Query Frame = 1
Query: 1330 DECLFPVCQ-----QICVNTIGSYQCSCREGFTLLSNGKCAINCLNNCNKNGD--CLNGICY---------CFSGWHGEDCS----LDIDECKYNHGCEHL----CVNVPGSFNCQCHSGFTLQINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCE--------FNDFCHFISPCEHN---CTTIND-NMVCSCLP-GYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAG-----LLCENDINEC-LNQTICQHV---CTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKD------------CVHGQCFNSK----CICKSGYRGKRCD-EDINECK--KYSHICEH------FCMNTEGSYKCSCMPGFILSANSHSCQSVCS----------LCKNGKCDFNNKCKCKTGWTGELCD---VDIDECLLNQHKCQHN----CVNSNGSYSCSCNLPF-------YLSTVDGRSCLEKNDSCSSPCKNGGKCVNSKCKCKPGYNGDSCE--EDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPH-CLNGGVCR 2805
+ECL PV IC++T GSY+C C+ GF L +GKC +N C + D +N +C C G+ D + DIDEC C + C+N PGSF C C GF+LQ I+ ECL C ++ C G NC N C I+ C N C +N + VC LP GY C CP GF +CEN NEC +N CQ C +T GSF C CK G D C+D D C +G+C N+ C C G+ D D++EC + S + ++ C+NT G ++C C GF++ NS C + LC N F +C C G+ +L + DI+EC N C C+N+ GS+ C CN+ + Y C++ N +C S + + +C CK GY D +INECQ S H + +C +T G+Y+C C GY K I + +C P+ CL G +C+
Sbjct: 4937 NECLNPVENDCVENAICIDTEGSYECRCKSGFKQLPSGKCEN--INECEEKSDNCSINSVCQDKADGFSCQCKPGFKWSDETNLNCEDIDECTNPTSCSSMPHSICMNNPGSFECVCPHGFSLQGGYCNDIN-----ECLIPNSCGQNSV-CANTVSGFNCSCANGARQLPNGDCELINECLENIDRCQVLNGADSVCYDLPIGY-------------------------ACVCPDGFVNDEVFPQVCENQ-NECEINIHSCQASNSECVDTYGSFKCVCKPGFSKNSDGD---------CVDYDECEISEQSNMKFCNNGKCINTAGGFTCDCPEGFIYNNYDCIDVDECSLDQVSSLADNCDQVNGHCINTVGGFQCYCNRGFVMIENSTKCVDIDECQFPNSCLDGLCNNLPGSF--ECLCNIGY--DLVNGKCTDINECSNNSQICGPQAAGICINAAGSFQCKCNVGYENSGGKSYNPCQSVNECVKLNITCPSNAQCVDRSNGYECICKDGYQEDQIGICRNINECQIEDSCHY-LADCLDTDGSYKCTCKYGY------KGDGIVSCKAICGPNSCLPGQLCQ 5472 HSP 4 Score: 89.3521 bits (220), Expect = 1.313e-17 Identity = 207/804 (25.75%), Postives = 301/804 (37.44%), Query Frame = 1
Query: 1045 FQGRCQCTEGFEGDQCQ--LEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGN--CKCKQGWK---GKFCNDDVDECLFPVCQQI---CVNTIGSYQCSCREGFTLLSNGKC--------AINCLN----------------NCNK-----NGDCL----------------------NGICYCFSGWHGE-DCSLDIDECKYNHGC---EHLCVNVPGSFNCQCHSGFTLQINKKKCISKSCNI--ECLNGGLCDKD----------KCKCPPGYIG---HNCEFNDFCHFISPCEHNCTTI----NDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNEN----------KCKCPKGFAGLLCE--NDINECLNQTI--CQHV--CTNTIGSFFCRCKNGHKLAEDK----RSCIPPNKKTCLDKDCVHGQCFNSKCICKSGYRGKRCD-EDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSVCSLCKNG----KCDFNNKCK---------CKTGW--TGELCDVDIDECLLNQHKCQHNCV--NSNGSYSCSCNLPFYLST---VDGRSCLEKNDSCSSPCKNGGKCVNS----KCKCKPGYN--GDSCEEDINECQWP---ISKHGCI---GECRNTFGNYECICPPGYLVLDDQKTCQISTKDTM----CNPHCLNGGVCRDMS-RCYCPIGFHGIDCG-VDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPHL 3021
F C+C G+EG + +I+ C G++ N T C N E +F C C+ G+ ++ C G+ + N C+CK G++ C D V+EC I C+NT GSY+C C E F KC A+ C +CN N +CL C+C SG++G+ + +D+DEC C N GSF+C C+ GF Q + ++ SC ECL C + KC+C G+IG ++C + C C + + I + C C + K C + +C+EN +C CP GF G NDI+EC N C + C N+ G + C C +G +D C C + C C G+ G DI+ECK C C+N G++ C C G + + + + C K +CD N CK C++G+ TG C + N K C N N C C F L + C K D+C N CV KC+CKPG+N G++C+ D NEC + C+ G C NT G++ C C + ++ +C+ M C+ + +D S C C GF I+ VDVDEC K C N GS+ C+C N L +C E P +
Sbjct: 3925 FGYICKCKPGYEGVGIKSCRDIDECG-GKINNCTINEDCSNT-EGSFTCSCKRGYSRNSSSGLCETNNVCNCGSHGICGPNYICQCKSGYEINPSGMCQD-VNECQTQSPCHILAQCINTPGSYKCQCPENFYGDPQNKCFEDKCKTKALQCQAGEVCKLSLYGSVCEKISCNSSEILINNECLPVNQVCQNINCGNHAFCKIENGRADCFCDSGYYGDGELCVDVDECSNGDVSCPNNSFCQNKDGSFHCACNVGF--QRLENALVTDSCTDIDECLLSESCATNGECQNTIGSFKCECKDGFIGDGKYDCRIDSKCEKYGGCHEDASCIVNVESSIYECQCHTEFSGDGITSCIKNNLCFVNGKSSCHENAICEQVNATYRCICPDGFQGDGYNFCNDIDECANDNTHNCSSLEKCVNSNGQYNCVCGDGAVYVDDICVDIDECSSNQTNKCSSNAICQNKEGTYSCQCAEGFYGDGLLCHDIDECKFGVANCSENALCINKPGTFACECQAGTLGNGTTCGDEDECKKPKGSPGAPECDENAVCKNKDPGYTCECQSGYKGTGWFCIKQTPCDVPNACKANQTCTPSNENSLAICECKPDFKLENDTCIPKTECENKTDNCDRETSN---CVQLDPGFKCECKPGFNMVGNTCQ-DKNECDPTSPDFAAQKCLASGGGCLNTKGSFVCTCNQEQMN-ENNSSCKPIDSCAMGLDNCDRKVEDCISSKDSSYTCQCIEGFQRINGSCVDVDECADKIDSCKNNATCNNMIGSYVCKCPDNLKLDLSKKACTDRNECQENPMI 4718 HSP 5 Score: 74.7146 bits (182), Expect = 3.934e-13 Identity = 99/325 (30.46%), Postives = 138/325 (42.46%), Query Frame = 1
Query: 2137 CICKSGYRGKRCD-EDINECKKYSHICEH--FCMNTEGSYKCSCMPGFILSANSHSCQSV-----CSLCKNGKCDFNNK-----CKCKTGW----TGELCDVDIDECLLNQHKCQH---NCVNSNGSYSCSCNLPFYLSTVDGRSCLEKND-SCSSPC-KNGGKCVNSK----CKCKPGYNGDSCE-EDINECQWPISKHGCIGECRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHG---IDCGVDVDECQRYA-PCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKEAVLKPH 3018
C CK+G+ G +DI+EC + +C+ FC NT GS+ CSC GF N +C ++ S C N + +K C+C+ G+ T CD D +EC + C NC N+ GSY C C F S +D C + N+ + C KN KC N+ C C GY GD DI+EC C N G+YEC C G D C + + T N C + +C+C GF + D+DEC A C + C N GS+ C+C Y + C + E + H
Sbjct: 3192 CHCKNGFMGDGIMCKDIDECSNNTSVCDSNAFCKNTIGSFSCSCKEGF--EGNGVTCTNINECYPLSPCDNATEECFDKVPGYECRCQKGFMKNTTTGNCD-DRNECADTGNLCDRVSTNCNNTFGSYRCDCKYGFRPSPIDSFVCTDVNECNLVHECDKNYAKCTNTPGSYYCTCDSGYQGDGRNCTDIDECSSNKVCQRPDATCVNLPGSYECRCLDGTPGCDGDNPCN-TVQCTKPNEICY-------LGQCFCKHGFQNNVTTNICEDIDECDTAANDCAGRKAKCANLDGSYECECLYGYRMSSINKICENINECIDNLH 3505 HSP 6 Score: 64.6994 bits (156), Expect = 4.737e-10 Identity = 106/400 (26.50%), Postives = 165/400 (41.25%), Query Frame = 1
Query: 1057 CQCTEGFEGDQ-----------CQLEINSCSRGQMGNRTCEHICVNEGENNFQCKCQSGFQLDNDGKSCIKEECSKFGTTEVVSGNCKCKQGWKGKFCNDDVDECLFPVCQQICVNTIGSYQCSCREGFTL-----LSNGKCAIN----CLNNCNK-NGDCLNGI----CYCFSGWHGEDCS---LDIDECKYNHGC-EHLCVNVPGSFNCQCHSGFTL-----------QINKKKCISKSCNIECLNGGLCDKDKCKCPPGYIGHNCEFNDFCHFISPCEHNCTTINDNMVCSCLPGYDLMPDKKTCKKLECPKCVRGTCNENKCKCPKGFAG---LLCENDINECLNQTICQHV--CTNTIGSFFCRCKNGHKLAEDKRSCIPPNKKTCLDKDCVHGQ 2121
C C +GF D+ C++ I+SC Q N C + +F+C C+ GF ++DG +EC + + KFCN+ C+NT G + C C EGF + +C+++ +NC++ NG C+N + CYC G+ + S +DIDEC++ + C + LC N+PGSF C C+ G+ L N + C ++ I C+N +CKC GY + + C ++ C + N+ C P C N +C C G+ +C N INEC + C ++ C +T GS+ C CK G+K + SC K C C+ GQ
Sbjct: 5135 CVCPDGFVNDEVFPQVCENQNECEINIHSC---QASNSECV-----DTYGSFKCVCKPGFSKNSDGDCVDYDEC-------------EISEQSNMKFCNNGK-----------CINTAGGFTCDCPEGFIYNNYDCIDVDECSLDQVSSLADNCDQVNGHCINTVGGFQCYCNRGFVMIENSTKCVDIDECQFPNSCLDGLCNNLPGSFECLCNIGYDLVNGKCTDINECSNNSQICGPQAAGI-CINAA--GSFQCKCNVGYENSGGKSYNPCQSVNEC------VKLNITC---------PSNAQCVDRS---------NGYECICKDGYQEDQIGICRN-INECQIEDSCHYLADCLDTDGSYKCTCKYGYK-GDGIVSC----KAICGPNSCLPGQ 5469 HSP 7 Score: 57.7658 bits (138), Expect = 6.242e-8 Identity = 74/240 (30.83%), Postives = 100/240 (41.67%), Query Frame = 1
Query: 2332 CDFNNK---CKCKTGWTGE--LCDVDIDECLLNQHKCQHN--CVNSNGSYSCSCNLPFYLSTVDGRSCLEKNDSCS-SPCKNG-----GKCVNSKCKCKPGYNGDSCE---EDINECQWPISKHGCIGE-CRNTFGNYECICPPGYLVLDDQKTCQISTKDTMCNPHCLNGGVCRDMSRCYCPIGFHGIDCGVDVDECQRYAPCDKLRGICYNTYGSFYCQCSSNYVLMYDGTSCMTMKE 3000
CDF + C CK G+ G+ +C DIDEC N C N C N+ GS+SCSC F +G +C N+ SPC N K +C+C+ G+ ++ +D NEC + + C NTFG+Y C C G+ P ++ VC DV+EC CDK C NT GS+YC C S Y DG +C + E
Sbjct: 3183 CDFKDDDYGCHCKNGFMGDGIMCK-DIDECSNNTSVCDSNAFCKNTIGSFSCSCKEGF---EGNGVTCTNINECYPLSPCDNATEECFDKVPGYECRCQKGFMKNTTTGNCDDRNECADTGNLCDRVSTNCNNTFGSYRCDCKYGF------------------RPSPIDSFVC------------------TDVNECNLVHECDKNYAKCTNTPGSYYCTCDSGY--QGDGRNCTDIDE 3380 The following BLAST results are available for this feature:
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses
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