C2H2-type domain-containing protein

Overview
NameC2H2-type domain-containing protein
Smed IDSMED30022398
Length (bp)3296
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of C2H2-type domain-containing protein (SMED30022398) t-SNE clustered cells

Violin plots show distribution of expression levels for C2H2-type domain-containing protein (SMED30022398) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of C2H2-type domain-containing protein (SMED30022398) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for C2H2-type domain-containing protein (SMED30022398) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30022398

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30022398h1SMcG0001510 Contig3970GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30022398h1SMcG0001510 Contig3970GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30022398h1SMcG0001510 Contig3970GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
BLAST of C2H2-type domain-containing protein vs. Ensembl Human
Match: HELZ (helicase with zinc finger [Source:HGNC Symbol;Acc:HGNC:16878])

HSP 1 Score: 183.726 bits (465), Expect = 1.978e-46
Identity = 210/780 (26.92%), Postives = 351/780 (45.00%), Query Frame = 3
Query: 1059 VVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTCRGVLSEELLGSIFKIIP-------NRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-------QKKLPILVLRKIDTSEIAL---PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            V + GI F+     T+RQ I FD      E    + + +D  S E LE L  + ++   ++T   ++    K  + F  +ETT    L + LL  I   IP        +  +  ++   NY + + D++ +EE+ Q   +SK   +  + I    M    S G   A +G+LFG  K       D  A  +++  V+  Y+    K K+   +      +    E ++ E + +  S++  E +N++     +  + F  +RL     H +L      D++  N +  P  +  P      TI + P    +E+       ++K  +L +    T+ +A+   P ++ G +GTGKT   A+ V  IL+ +  S ILICT S SA +LY++ +                        K +  +V+   LI S+H        + F     E+I   +RV + T+       S +   L+ +   F +I +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D   I V +P+  QV  IR  LR K L+ V VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E ++L
Sbjct:  346 VYKVGIAFNTEIFGTFRQTIVFDFGL---EPVLMQRVMIDAASTEDLEYLMHAKQQ---LVTTAKRWDSSSKTIIDFEPNETT---DLEKSLL--IRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYAL------DRIKDNGVLFPDISMTP------TIPWSPNRQWDEQLDPRLNAKQKEAVLAI----TTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAH--------STFQMPQKEDIL-KHRVVVVTLNT-----SQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL 1078          
BLAST of C2H2-type domain-containing protein vs. Ensembl Human
Match: HELZ (helicase with zinc finger [Source:HGNC Symbol;Acc:HGNC:16878])

HSP 1 Score: 181.8 bits (460), Expect = 1.212e-45
Identity = 212/779 (27.21%), Postives = 351/779 (45.06%), Query Frame = 3
Query: 1059 VVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTCRGVLSEELLGSIFKIIP-------NRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-------QKKLPILVLRKIDTSEIAL---PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            V + GI F+     T+RQ I FD      E    + + +D  S E LE L  + ++   ++T   ++    K  + F  +ETT    L + LL  I   IP        +  +  ++   NY + + D++ +EE+ Q   +SK   +  + I    M    S G   A +G+LFG  K       D  A  +++  V+  Y+    K K+   +      +    E ++ E + +  S++  E +N++     +  + F  +RL     H +L      D++  N +  P  +  P      TI + P    +E+       ++K  +L +    T+ +A+   P ++ G +GTGKT   A+ V  IL+ +  S ILICT S SA +LY++ +                        K +  +V+   LI S+H        + F     E+I   +RV + T+ N +  L      LE    F +I +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D   I V +P+  QV  IR  LR K L+ V VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E ++L
Sbjct:  346 VYKVGIAFNTEIFGTFRQTIVFDFGL---EPVLMQRVMIDAASTEDLEYLMHAKQQ---LVTTAKRWDSSSKTIIDFEPNETT---DLEKSLL--IRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYAL------DRIKDNGVLFPDISMTP------TIPWSPNRQWDEQLDPRLNAKQKEAVLAI----TTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAH--------STFQMPQKEDIL-KHRVVVVTL-NTSQYLCQL--DLEP-GFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL 1078          
BLAST of C2H2-type domain-containing protein vs. Ensembl Human
Match: HELZ (helicase with zinc finger [Source:HGNC Symbol;Acc:HGNC:16878])

HSP 1 Score: 177.948 bits (450), Expect = 1.866e-44
Identity = 211/779 (27.09%), Postives = 352/779 (45.19%), Query Frame = 3
Query: 1059 VVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTCRGVLSEELLGSIFKIIP-------NRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-------QKKLPILVLRKIDTSEIAL---PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            V + GI F+     T+RQ I FD      E    + + +D  S E LE L  + ++   ++T   ++    K  + F  +ETT    L + LL  I   IP        +  +  ++   NY + + D++ +EE+ Q   +SK   +  + I    M    S G   A +G+LFG  K       D  A  +++  V+  Y+    K K+   +      +    E ++ E + +  S++  E +N++     +  + F  +RL     H +L      D++  N +  P  +  P      TI + P    +E+       ++K  +L +    T+ +A+   P ++ G +GTGKT   A+ V  IL+ + ++ ILICT S SA +LY++ +                        K +  +V+   LI S+H        + F     E+I   +RV + T+ N +  L      LE    F +I +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D   I V +P+  QV  IR  LR K L+ V VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E ++L
Sbjct:  346 VYKVGIAFNTEIFGTFRQTIVFDFGL---EPVLMQRVMIDAASTEDLEYLMHAKQQ---LVTTAKRWDSSSKTIIDFEPNETT---DLEKSLL--IRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYAL------DRIKDNGVLFPDISMTP------TIPWSPNRQWDEQLDPRLNAKQKEAVLAI----TTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQ-ETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAH--------STFQMPQKEDIL-KHRVVVVTL-NTSQYLCQL--DLEP-GFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL 1077          
BLAST of C2H2-type domain-containing protein vs. Ensembl Human
Match: HELZ2 (helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021])

HSP 1 Score: 116.701 bits (291), Expect = 1.775e-25
Identity = 98/415 (23.61%), Postives = 186/415 (44.82%), Query Frame = 3
Query: 2010 PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNG-------IKLIKSSHKRKGAEKNTI----FSDEL------TEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVP------IICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYET----QLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKN--KSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDE 3167
            P ++ G FGTGKT   A   + ++    ++ +LICT + SA ++Y++   +Y    V+G       ++++ +       +  T+     +D+       T      +RV +TT   A +   +  P+      F++I +DEAAQ+LE +A+    + ++ T+ + AGD  Q  P L++ +  + +         +C     +++ +   +   E YR   AIV+++S+  Y            + P  +  P+MF   + +        D  + S+ N  E+  VVE V E        +   + + +      AQV  +R  LR + L +V V     + G ++ VV +STV +         L P F ++  ++N V++RA+  + V+GD ++L +       W +FI  C E
Sbjct:  539 PLLIYGPFGTGKTYTLAMASLEVIRRP-ETKVLICTHTNSAADIYIR---EYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARE---LRVPV----GFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDR-----DMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVE 937          
BLAST of C2H2-type domain-containing protein vs. Ensembl Human
Match: HELZ2 (helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021])

HSP 1 Score: 98.5969 bits (244), Expect = 4.609e-20
Identity = 77/316 (24.37%), Postives = 141/316 (44.62%), Query Frame = 3
Query: 2256 TEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVP------IICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYET----QLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKN--KSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDE 3167
            T      +RV +TT   A +   +  P+      F++I +DEAAQ+LE +A+    + ++ T+ + AGD  Q  P L++ +  + +         +C     +++ +   +   E YR   AIV+++S+  Y            + P  +  P+MF   + +        D  + S+ N  E+  VVE V E        +   + + +      AQV  +R  LR + L +V V     + G ++ VV +STV +         L P F ++  ++N V++RA+  + V+GD ++L +       W +FI  C E
Sbjct:   65 TRAELARHRVVVTTTSQARE---LRVPV----GFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDR-----DMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVE 368          
BLAST of C2H2-type domain-containing protein vs. Ensembl Celegans
Match: C05C10.2 (Uncharacterized ATP-dependent helicase C05C10.2 [Source:UniProtKB/Swiss-Prot;Acc:Q09449])

HSP 1 Score: 64.3142 bits (155), Expect = 6.043e-10
Identity = 78/308 (25.32%), Postives = 121/308 (39.29%), Query Frame = 3
Query: 2310 ADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAI-MVYQFGNYKTKFIFAGDIFQTRP---ELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLIS----LMKPTYQI----------VPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            ADS      IL  +     + +DEA+Q+ E   + ++  F N    F   GDI Q  P   E     L+ F +          K+      TLR VYR HP     LS+ ++Y+  L+S    L +  +             PMMF +++   +       K   S  N  E  IV E V  L+ +     + S I V S + AQ  ++ + LR   +    V+     QG E +++ + +      D         F    N +N+ +SRAK    +IG    L   N     WST +   ++  NL
Sbjct: 1190 ADSAKGLLNILRDVCA---VQIDEASQLAECTLLGLLKSFNN--ASFGLIGDIHQLPPYCEEGLEGKLKDFGIGNTMERAIKEKMFP--VCTLRNVYRCHPKTTELLSE-LFYDGALVSGVSELARSDFMTKRDDFWPNPKFPMMFVNNTGAST-------KMGTSTSNSSEKSIVGEIVQNLINDPRNPVNPSDIGVISFYSAQTSILTEHLRGSGVKCGTVDA---FQGSEKEIIIMCSTNERISD---------FMQLSNRLNVAMSRAKQVTIIIGHLDGLRRAN----YWSTIVNKIEQNGNL 1466          
BLAST of C2H2-type domain-containing protein vs. Ensembl Celegans
Match: C05C10.2 (Uncharacterized ATP-dependent helicase C05C10.2 [Source:UniProtKB/Swiss-Prot;Acc:Q09449])

HSP 1 Score: 63.929 bits (154), Expect = 6.575e-10
Identity = 78/308 (25.32%), Postives = 121/308 (39.29%), Query Frame = 3
Query: 2310 ADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAI-MVYQFGNYKTKFIFAGDIFQTRP---ELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLIS----LMKPTYQI----------VPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            ADS      IL  +     + +DEA+Q+ E   + ++  F N    F   GDI Q  P   E     L+ F +          K+      TLR VYR HP     LS+ ++Y+  L+S    L +  +             PMMF +++   +       K   S  N  E  IV E V  L+ +     + S I V S + AQ  ++ + LR   +    V+     QG E +++ + +      D         F    N +N+ +SRAK    +IG    L   N     WST +   ++  NL
Sbjct: 1190 ADSAKGLLNILRDVCA---VQIDEASQLAECTLLGLLKSFNN--ASFGLIGDIHQLPPYCEEGLEGKLKDFGIGNTMERAIKEKMFP--VCTLRNVYRCHPKTTELLSE-LFYDGALVSGVSELARSDFMTKRDDFWPNPKFPMMFVNNTGAST-------KMGTSTSNSSEKSIVGEIVQNLINDPRNPVNPSDIGVISFYSAQTSILTEHLRGSGVKCGTVDA---FQGSEKEIIIMCSTNERISD---------FMQLSNRLNVAMSRAKQVTIIIGHLDGLRRAN----YWSTIVNKIEQNGNL 1466          
BLAST of C2H2-type domain-containing protein vs. Ensembl Celegans
Match: Y106G6D.5 (pep chromosome:WBcel235:I:10119209:10121815:-1 gene:WBGene00014965.1 transcript:Y106G6D.5b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y106G6D.5)

HSP 1 Score: 56.225 bits (134), Expect = 1.161e-7
Identity = 101/420 (24.05%), Postives = 172/420 (40.95%), Query Frame = 3
Query: 2013 FILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVF--ITTIENAADSLSMFFPILEKLS---------IFNYIF-----------------------------VDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPE--LYNKSLR-KFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQL--------ISLMK-----PTYQIV--PMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGD 3098
              + G  GTGKT V AE V  +++   K  +L+C  ++ A    M              ++I+   + K  ++  + ++  T++ F N++    +  I+    ++S   P+ +K+S         IF  IF                             VDEAAQ  E    +         K I  GD  Q  P   L +K+++  F + ++ +L   +    N  I L E YR +  I+N+ S  ++YE QL        I+L       P   ++  P+M  +  +      + F+    SF N  E+ +V E V  L+ +     +   I V SP+YAQ+    ++LR     RV V      QG E  VV I  ++  +D+  I  L+ T       +N+ V+RA+    +IG+
Sbjct:  150 LCIQGPPGTGKTRVIAEIVHQLMKK--KKKVLVCAPTHVAVRNAMDATTG---------RMIEEMPEEKAEQQLCLLAN--TKDEFQNHKSASKLEEIKKQLSTMSTSDPLYKKMSYEYYLIRNSIFRSIFYPKLAVFSTLGTSSIQKLPEYHWNADVMIVDEAAQCTEPATWVPVLTTPSCKKLILVGDQKQL-PAVVLSDKAMKGNFKLSLMEKLAEEFSS-NNINILLNEQYRMNKKIMNW-SNEVFYENQLTAHSTVSDITLRDICPNLPEDHVLNNPIMMINMENVKDRSHEEFESH--SFTNTDELNLVTEYVNRLVVD--LGINPKAIAVISPYYAQI----EKLRRSIPFRVDVNTVDAFQGHERQVV-IFCLVRDNDEGQIGFLNETRR-----LNVAVTRARRQFVLIGN 539          
BLAST of C2H2-type domain-containing protein vs. Ensembl Celegans
Match: Y106G6D.5 (pep chromosome:WBcel235:I:10119209:10122171:-1 gene:WBGene00014965.1 transcript:Y106G6D.5a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y106G6D.5)

HSP 1 Score: 56.225 bits (134), Expect = 1.268e-7
Identity = 101/420 (24.05%), Postives = 172/420 (40.95%), Query Frame = 3
Query: 2013 FILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVF--ITTIENAADSLSMFFPILEKLS---------IFNYIF-----------------------------VDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPE--LYNKSLR-KFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQL--------ISLMK-----PTYQIV--PMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGD 3098
              + G  GTGKT V AE V  +++   K  +L+C  ++ A    M              ++I+   + K  ++  + ++  T++ F N++    +  I+    ++S   P+ +K+S         IF  IF                             VDEAAQ  E    +         K I  GD  Q  P   L +K+++  F + ++ +L   +    N  I L E YR +  I+N+ S  ++YE QL        I+L       P   ++  P+M  +  +      + F+    SF N  E+ +V E V  L+ +     +   I V SP+YAQ+    ++LR     RV V      QG E  VV I  ++  +D+  I  L+ T       +N+ V+RA+    +IG+
Sbjct:  241 LCIQGPPGTGKTRVIAEIVHQLMKK--KKKVLVCAPTHVAVRNAMDATTG---------RMIEEMPEEKAEQQLCLLAN--TKDEFQNHKSASKLEEIKKQLSTMSTSDPLYKKMSYEYYLIRNSIFRSIFYPKLAVFSTLGTSSIQKLPEYHWNADVMIVDEAAQCTEPATWVPVLTTPSCKKLILVGDQKQL-PAVVLSDKAMKGNFKLSLMEKLAEEFSS-NNINILLNEQYRMNKKIMNW-SNEVFYENQLTAHSTVSDITLRDICPNLPEDHVLNNPIMMINMENVKDRSHEEFESH--SFTNTDELNLVTEYVNRLVVD--LGINPKAIAVISPYYAQI----EKLRRSIPFRVDVNTVDAFQGHERQVV-IFCLVRDNDEGQIGFLNETRR-----LNVAVTRARRQFVLIGN 630          
BLAST of C2H2-type domain-containing protein vs. Ensembl Celegans
Match: dna-2 (Yeast DNA helicase/endonuclease family [Source:UniProtKB/TrEMBL;Acc:Q9U3F2])

HSP 1 Score: 55.4546 bits (132), Expect = 2.345e-7
Identity = 101/437 (23.11%), Postives = 184/437 (42.11%), Query Frame = 3
Query: 1941 LNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTI---FSDELTEEIFTNNR-VFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLI---------SLMKPTYQIVPM-------------------MFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIE 3155
            LN EQ+K  +  L   D        ++ G  G+GKT + +  +  ++    K  +L+   ++SA +  +    K +      ++L  SS  +   +K T+     +E +EE +   R V  TT   A     +   +L     F+ + VDEA+ VLE   + V    N   KF+  GD  Q  P + ++  ++     I  +  + +      ++L   YR +  I + LS  ++YE +LI         SL +    IV M                   +F D+ ST+++++Q  D +     N+ E K++ E   + + +        +I V S +  QV  IR  L S  L    ++   + QG E  V+  S   +++      +L      +   +N+ ++RA+  + V+G K S  T+ P   ++S  IE
Sbjct:  650 LNNEQRKAVVHALATEDF------MMVEGLPGSGKTTLISVLIQCLVATNKK--VLLAAFTHSAVDNILTKLTKEVA-AEKILRLGSSSSIKDDIKKMTLKAKLENETSEEYYAAVRKVMKTTPIVACTCHHVPRELLFSYRHFDVVIVDEASMVLEPLLLPVLATSN---KFVLVGDCKQLTPLVVSRKAKQEGAG-ISTMEKLQQSHPGVVVSLTSQYRMNREI-SVLSSKLFYENRLICGNESVSRSSLDRTGDYIVAMDDGSDHIRKALSGDIKDSCVFLDTQSTINSKMQCEDGEGGGMCNDGEAKLISELCQQFVMS---GVKPHEIGVMSAYRRQVDHIRGILNSDELEVNTID---SYQGREKRVIIWSLTWTNNSTKKSELL-----KDERRVNVALTRARQKLVVVGCKNSAETI-PVLFRFSQLIE 1060          
BLAST of C2H2-type domain-containing protein vs. Ensembl Fly
Match: CG9425 (gene:FBgn0036451 transcript:FBtr0075693)

HSP 1 Score: 196.052 bits (497), Expect = 2.421e-50
Identity = 240/1015 (23.65%), Postives = 427/1015 (42.07%), Query Frame = 3
Query:  546 CWFCLKDIASENSIPLHIESQPHKAKYDADKKRQWYFKMPCSQIALRSSDV------------NQNGITNQIDDEYLEMCARIKFRE-----------FLSSYTYEHIERKINPWPKFMEFKIPFFPSNIKCYKSP-----IQIFPTLSISLRCHKL-------------AIYLRDDESRPFFKL--------------IKANQNQTVEHRSQLLTVCLKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDV---GSNEHLENLK-----SSWERYKDVITQEVKYKNYVPFNMSETTCRGVLSEE--LL-------GSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITI-KNHLMTSSGLIPAND-----GKLFGDVKFGR--HHDQAAREIIIKCVSNCYVA--------FDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-QKKLPILVLRKIDTSEIAL-----PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIK----LIKSSHKRKGAEKNTI-----FSDEL------TEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNK--SLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTY-QIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQ---SKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS---------------------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            C +C     + N +  H +++ H+    +D+ R W ++ P     L +  +                +     DE  E   R ++R            +  SYT + ++R I              P  + C + P      +     SIS +  K              A+ L  D  R  F L              +K++Q       SQ  T    ++    + E  +EF      T+RQ I FD+     E    + + VDV      E +E +K     SS  R+    TQ  +++  +  ++        L  E  LL        + F +      ++  +  +NY + + +++ +EE+ +   +++      +T+  N+++T +G+  +       G+LF  ++ G+    D +   +I+   S+ Y++         D  K  ++E  +        E +    + +  S + VE + ++    +E  I F  +R+ +   H +++ +            + F    P  E E +I + PK    +  + KL       ++    AL     P +L G FGTGKT   A+ +  +L  + ++ ILICT S SA +LY++ +    P +  G+K    L    HKR  A  N +      +D +      T E    +R+ + T+  + +  ++  P      +F +IF+DEAAQ +E +AIM     N  T+ + AGD  Q  PEL++     RK  + ++ RL++ Y       I L E YR H AI+ + S+ ++YE +L++  K P + +  P+ FF   +T   ++Q  DK+  +F N  EV  VVE V EL K    ++ +   + I + +P+  QV  IR  LR + +  + VE+  N+QG ++  VF+STV +                     +D D G       F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FIE+CDE  +L
Sbjct:  281 CSYCTITFQTRNELRQHCQTEAHQKVIMSDEGRDWKWRPPPRGYTLDTYSLCETFSEAHICHYGAQCVEAHGQDELNEWKERFEYRRMRMQKACEKELYGKSYTEQVLDRWIQA----------TAPERVMCERVPDMEARCEQQLVTSISSKTSKREWLFQLETKKPLKAVALLQDAHRNHFALKSIKMCKPTESSMELKSDQEWLAGSSSQSETS--NEDSATLIHEITVEFHTEIYGTFRQAICFDVGQ---EPLLVRHLCVDVLPVNDAEKIEEIKRDIINSSATRWDVANTQLTRFETTIGTHLKTEAYLSDLEHERELLERYPCPRAATFTLT-QSTIVEKRLTQNNYRSRIHELLSVEEIARYEQIARYNVRTRLTVASNYILTPAGMATSTAKYSLAGELFALMRLGKDISEDTSPGRLILSNCSSVYISKPEDPDSKADPTKRAVYEALI--------EDKGKNVIYLKLSAKCVEAMALQADTELEVDIQFQLNRMPYCEWHNAVDKI------------TDFRLIFPATELEPSIPWTPKKQWADSCEPKLNAKQREAVNAITTALSIKLPPILLIGPFGTGKTYTLAQAIKQLL-TQPEAKILICTHSNSAADLYIKEYLH--PWIEEGLKEATPLRVYYHKRWSATVNGVVQKYCITDGVGNFLRPTVEDIMRHRIVVVTLSISMELATLGLPK----GLFTHIFLDEAAQAMECEAIMPLALANDSTRIVLAGDHMQMSPELFSAFAKERKLHISLLERLYDHYPSNFPCKILLCENYRAHEAIIRFTSE-LFYEQKLVASGKQPRHDRFYPLTFF---TTRGEDVQ--DKNSTAFYNNAEVYEVVERVSELRKRWPSAWGKLNDTSIGIMTPYSDQVFRIRSELRKRRMGGISVERVLNVQGKQFRAVFLSTVRTRRTCMPQGSAPGSASTTSIGDADADYG-------FLSNSKLLNTAITRAQSLVAVVGDPVALCSIGRCRKVWERFIEICDEHKSL 1239          
BLAST of C2H2-type domain-containing protein vs. Ensembl Fly
Match: CG9425 (gene:FBgn0036451 transcript:FBtr0333075)

HSP 1 Score: 196.052 bits (497), Expect = 2.421e-50
Identity = 240/1015 (23.65%), Postives = 427/1015 (42.07%), Query Frame = 3
Query:  546 CWFCLKDIASENSIPLHIESQPHKAKYDADKKRQWYFKMPCSQIALRSSDV------------NQNGITNQIDDEYLEMCARIKFRE-----------FLSSYTYEHIERKINPWPKFMEFKIPFFPSNIKCYKSP-----IQIFPTLSISLRCHKL-------------AIYLRDDESRPFFKL--------------IKANQNQTVEHRSQLLTVCLKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDV---GSNEHLENLK-----SSWERYKDVITQEVKYKNYVPFNMSETTCRGVLSEE--LL-------GSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITI-KNHLMTSSGLIPAND-----GKLFGDVKFGR--HHDQAAREIIIKCVSNCYVA--------FDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-QKKLPILVLRKIDTSEIAL-----PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIK----LIKSSHKRKGAEKNTI-----FSDEL------TEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNK--SLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTY-QIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQ---SKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS---------------------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            C +C     + N +  H +++ H+    +D+ R W ++ P     L +  +                +     DE  E   R ++R            +  SYT + ++R I              P  + C + P      +     SIS +  K              A+ L  D  R  F L              +K++Q       SQ  T    ++    + E  +EF      T+RQ I FD+     E    + + VDV      E +E +K     SS  R+    TQ  +++  +  ++        L  E  LL        + F +      ++  +  +NY + + +++ +EE+ +   +++      +T+  N+++T +G+  +       G+LF  ++ G+    D +   +I+   S+ Y++         D  K  ++E  +        E +    + +  S + VE + ++    +E  I F  +R+ +   H +++ +            + F    P  E E +I + PK    +  + KL       ++    AL     P +L G FGTGKT   A+ +  +L  + ++ ILICT S SA +LY++ +    P +  G+K    L    HKR  A  N +      +D +      T E    +R+ + T+  + +  ++  P      +F +IF+DEAAQ +E +AIM     N  T+ + AGD  Q  PEL++     RK  + ++ RL++ Y       I L E YR H AI+ + S+ ++YE +L++  K P + +  P+ FF   +T   ++Q  DK+  +F N  EV  VVE V EL K    ++ +   + I + +P+  QV  IR  LR + +  + VE+  N+QG ++  VF+STV +                     +D D G       F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FIE+CDE  +L
Sbjct:  281 CSYCTITFQTRNELRQHCQTEAHQKVIMSDEGRDWKWRPPPRGYTLDTYSLCETFSEAHICHYGAQCVEAHGQDELNEWKERFEYRRMRMQKACEKELYGKSYTEQVLDRWIQA----------TAPERVMCERVPDMEARCEQQLVTSISSKTSKREWLFQLETKKPLKAVALLQDAHRNHFALKSIKMCKPTESSMELKSDQEWLAGSSSQSETS--NEDSATLIHEITVEFHTEIYGTFRQAICFDVGQ---EPLLVRHLCVDVLPVNDAEKIEEIKRDIINSSATRWDVANTQLTRFETTIGTHLKTEAYLSDLEHERELLERYPCPRAATFTLT-QSTIVEKRLTQNNYRSRIHELLSVEEIARYEQIARYNVRTRLTVASNYILTPAGMATSTAKYSLAGELFALMRLGKDISEDTSPGRLILSNCSSVYISKPEDPDSKADPTKRAVYEALI--------EDKGKNVIYLKLSAKCVEAMALQADTELEVDIQFQLNRMPYCEWHNAVDKI------------TDFRLIFPATELEPSIPWTPKKQWADSCEPKLNAKQREAVNAITTALSIKLPPILLIGPFGTGKTYTLAQAIKQLL-TQPEAKILICTHSNSAADLYIKEYLH--PWIEEGLKEATPLRVYYHKRWSATVNGVVQKYCITDGVGNFLRPTVEDIMRHRIVVVTLSISMELATLGLPK----GLFTHIFLDEAAQAMECEAIMPLALANDSTRIVLAGDHMQMSPELFSAFAKERKLHISLLERLYDHYPSNFPCKILLCENYRAHEAIIRFTSE-LFYEQKLVASGKQPRHDRFYPLTFF---TTRGEDVQ--DKNSTAFYNNAEVYEVVERVSELRKRWPSAWGKLNDTSIGIMTPYSDQVFRIRSELRKRRMGGISVERVLNVQGKQFRAVFLSTVRTRRTCMPQGSAPGSASTTSIGDADADYG-------FLSNSKLLNTAITRAQSLVAVVGDPVALCSIGRCRKVWERFIEICDEHKSL 1239          
BLAST of C2H2-type domain-containing protein vs. Ensembl Fly
Match: CG9425 (gene:FBgn0036451 transcript:FBtr0333074)

HSP 1 Score: 196.052 bits (497), Expect = 2.421e-50
Identity = 240/1015 (23.65%), Postives = 427/1015 (42.07%), Query Frame = 3
Query:  546 CWFCLKDIASENSIPLHIESQPHKAKYDADKKRQWYFKMPCSQIALRSSDV------------NQNGITNQIDDEYLEMCARIKFRE-----------FLSSYTYEHIERKINPWPKFMEFKIPFFPSNIKCYKSP-----IQIFPTLSISLRCHKL-------------AIYLRDDESRPFFKL--------------IKANQNQTVEHRSQLLTVCLKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDV---GSNEHLENLK-----SSWERYKDVITQEVKYKNYVPFNMSETTCRGVLSEE--LL-------GSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITI-KNHLMTSSGLIPAND-----GKLFGDVKFGR--HHDQAAREIIIKCVSNCYVA--------FDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-QKKLPILVLRKIDTSEIAL-----PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIK----LIKSSHKRKGAEKNTI-----FSDEL------TEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNK--SLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTY-QIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQ---SKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS---------------------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            C +C     + N +  H +++ H+    +D+ R W ++ P     L +  +                +     DE  E   R ++R            +  SYT + ++R I              P  + C + P      +     SIS +  K              A+ L  D  R  F L              +K++Q       SQ  T    ++    + E  +EF      T+RQ I FD+     E    + + VDV      E +E +K     SS  R+    TQ  +++  +  ++        L  E  LL        + F +      ++  +  +NY + + +++ +EE+ +   +++      +T+  N+++T +G+  +       G+LF  ++ G+    D +   +I+   S+ Y++         D  K  ++E  +        E +    + +  S + VE + ++    +E  I F  +R+ +   H +++ +            + F    P  E E +I + PK    +  + KL       ++    AL     P +L G FGTGKT   A+ +  +L  + ++ ILICT S SA +LY++ +    P +  G+K    L    HKR  A  N +      +D +      T E    +R+ + T+  + +  ++  P      +F +IF+DEAAQ +E +AIM     N  T+ + AGD  Q  PEL++     RK  + ++ RL++ Y       I L E YR H AI+ + S+ ++YE +L++  K P + +  P+ FF   +T   ++Q  DK+  +F N  EV  VVE V EL K    ++ +   + I + +P+  QV  IR  LR + +  + VE+  N+QG ++  VF+STV +                     +D D G       F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FIE+CDE  +L
Sbjct:  281 CSYCTITFQTRNELRQHCQTEAHQKVIMSDEGRDWKWRPPPRGYTLDTYSLCETFSEAHICHYGAQCVEAHGQDELNEWKERFEYRRMRMQKACEKELYGKSYTEQVLDRWIQA----------TAPERVMCERVPDMEARCEQQLVTSISSKTSKREWLFQLETKKPLKAVALLQDAHRNHFALKSIKMCKPTESSMELKSDQEWLAGSSSQSETS--NEDSATLIHEITVEFHTEIYGTFRQAICFDVGQ---EPLLVRHLCVDVLPVNDAEKIEEIKRDIINSSATRWDVANTQLTRFETTIGTHLKTEAYLSDLEHERELLERYPCPRAATFTLT-QSTIVEKRLTQNNYRSRIHELLSVEEIARYEQIARYNVRTRLTVASNYILTPAGMATSTAKYSLAGELFALMRLGKDISEDTSPGRLILSNCSSVYISKPEDPDSKADPTKRAVYEALI--------EDKGKNVIYLKLSAKCVEAMALQADTELEVDIQFQLNRMPYCEWHNAVDKI------------TDFRLIFPATELEPSIPWTPKKQWADSCEPKLNAKQREAVNAITTALSIKLPPILLIGPFGTGKTYTLAQAIKQLL-TQPEAKILICTHSNSAADLYIKEYLH--PWIEEGLKEATPLRVYYHKRWSATVNGVVQKYCITDGVGNFLRPTVEDIMRHRIVVVTLSISMELATLGLPK----GLFTHIFLDEAAQAMECEAIMPLALANDSTRIVLAGDHMQMSPELFSAFAKERKLHISLLERLYDHYPSNFPCKILLCENYRAHEAIIRFTSE-LFYEQKLVASGKQPRHDRFYPLTFF---TTRGEDVQ--DKNSTAFYNNAEVYEVVERVSELRKRWPSAWGKLNDTSIGIMTPYSDQVFRIRSELRKRRMGGISVERVLNVQGKQFRAVFLSTVRTRRTCMPQGSAPGSASTTSIGDADADYG-------FLSNSKLLNTAITRAQSLVAVVGDPVALCSIGRCRKVWERFIEICDEHKSL 1239          
BLAST of C2H2-type domain-containing protein vs. Ensembl Fly
Match: CG6967 (gene:FBgn0034187 transcript:FBtr0300276)

HSP 1 Score: 62.7734 bits (151), Expect = 1.648e-9
Identity = 95/425 (22.35%), Postives = 179/425 (42.12%), Query Frame = 3
Query: 2010 PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKN----TIFSDELTEEIFTNNRVFITTIENAADSL-----------------------SMFFPILEKLSIFNYIFVDEAAQVLEVDAIM----VYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRL------HNIYK------LLKNYTITLREVYRTHPAIVNYLSQAIYYETQLIS---------------LMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSL 3110
            P+IL G  GTGKT    E ++ +   + +S IL+   S SA +       +YI    + I+L +   ++K  E +     ++S  + E+ F +    +    N + S+                        +    L + + F +IF+DEA    E +A++    + Q  +     I +GD  Q    +  KS R  S+ +   L       + YK        +N  + L   YR+HP IV   ++ +YY  +L +               L  P + I+    F ++  ++N     +++  S  N  E +++   V  L+ ++     Q  + + +P+ AQ KL+   L+SK    V V      QG E  ++ I++++ S  + G       F  N   +N+++SRAK  + ++G+ ++L
Sbjct:  270 PYILFGPPGTGKTTTIVEAILQLRLQQPQSRILVTAGSNSACDTIALKLCEYIE---SNIRLQEHFAQQKLPEPDHQLIRVYSRSIYEKGFASVPSLLLKNSNCSKSIYDHIKASRIVKYGIIVATLCTVARLVTDTLGRYNFFTHIFIDEAGASTEPEALIGIMGIKQTAD--CHVILSGDHKQLGAVI--KSNRAASLGLSRSLMERLLQSDCYKSDENGNYDRNRQMRLCRNYRSHPQIVRLFNE-LYYNGELKAQAPAMDVNLAANWSVLTNPQFPII----FQATHGVTNR----EQNSTSSYNNLEAEVICWYVKRLINDRVVG--QEDVGIVAPYTAQGKLVTKLLQSKGYPNVEVGSVETYQGREKTII-IASLVKSFTNMG-------FMCNPRRVNVLLSRAKALLILVGNPVTL 668          
BLAST of C2H2-type domain-containing protein vs. Ensembl Fly
Match: CG6967 (gene:FBgn0034187 transcript:FBtr0300277)

HSP 1 Score: 62.7734 bits (151), Expect = 1.648e-9
Identity = 95/425 (22.35%), Postives = 179/425 (42.12%), Query Frame = 3
Query: 2010 PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKN----TIFSDELTEEIFTNNRVFITTIENAADSL-----------------------SMFFPILEKLSIFNYIFVDEAAQVLEVDAIM----VYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRL------HNIYK------LLKNYTITLREVYRTHPAIVNYLSQAIYYETQLIS---------------LMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSL 3110
            P+IL G  GTGKT    E ++ +   + +S IL+   S SA +       +YI    + I+L +   ++K  E +     ++S  + E+ F +    +    N + S+                        +    L + + F +IF+DEA    E +A++    + Q  +     I +GD  Q    +  KS R  S+ +   L       + YK        +N  + L   YR+HP IV   ++ +YY  +L +               L  P + I+    F ++  ++N     +++  S  N  E +++   V  L+ ++     Q  + + +P+ AQ KL+   L+SK    V V      QG E  ++ I++++ S  + G       F  N   +N+++SRAK  + ++G+ ++L
Sbjct:  270 PYILFGPPGTGKTTTIVEAILQLRLQQPQSRILVTAGSNSACDTIALKLCEYIE---SNIRLQEHFAQQKLPEPDHQLIRVYSRSIYEKGFASVPSLLLKNSNCSKSIYDHIKASRIVKYGIIVATLCTVARLVTDTLGRYNFFTHIFIDEAGASTEPEALIGIMGIKQTAD--CHVILSGDHKQLGAVI--KSNRAASLGLSRSLMERLLQSDCYKSDENGNYDRNRQMRLCRNYRSHPQIVRLFNE-LYYNGELKAQAPAMDVNLAANWSVLTNPQFPII----FQATHGVTNR----EQNSTSSYNNLEAEVICWYVKRLINDRVVG--QEDVGIVAPYTAQGKLVTKLLQSKGYPNVEVGSVETYQGREKTII-IASLVKSFTNMG-------FMCNPRRVNVLLSRAKALLILVGNPVTL 668          
BLAST of C2H2-type domain-containing protein vs. Ensembl Zebrafish
Match: helz (helicase with zinc finger [Source:NCBI gene;Acc:406550])

HSP 1 Score: 173.326 bits (438), Expect = 3.519e-43
Identity = 213/836 (25.48%), Postives = 363/836 (43.42%), Query Frame = 3
Query:  936 IYLRDDESRPFFKL--IKANQNQTVEHRSQLLTVC--------LKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQ---EVKYKNYVPFNMSETTC--RGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYES----RSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-------QKKLPILVLRKIDTSEIAL---PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDEL-TEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK--PTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS----------------------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            I L  D +RP F +  + A     +E +      C        +++    C+    I FS     T+RQ + FDL     E    + + VD  S E LE+L  +  R + ++T    +   K  V F  +E     R +L+   +      +  +  +  T+   NY   + D++ +EE+ Q   +SK   +  + +    M    S G   A +G+LF   K       D  A  +++  V N  +    FK  + + +        YE+    ++ + + +   K+  + + +   + ++  + F  +RL     H +L      D++  N +  P  +  P      TI + P    +E+       ++K  IL +    T+ +++   P ++ G +GTGKT   A+ V  IL+ + +S +LICT S SA +LY++ +                        K +  LV    LI  +H          F+ ++ T +    +RV + T+     S S +   L+ +  IF +I +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S  ++YE +L++  K  P     P+ FF +         V +K+  ++ N  EV  +VE V E+ K    S+   ++  I V SP+  QV  IR  LR K ++ V VE+  N+QG ++ V+F+STV +                       D D G       F SN  L+N  ++RA+  VAV+GD ++L +V   R  W TFI +C E  +L
Sbjct:  286 IALLYDANRPHFSIAAVSAGDASALEPQPVCPGGCQEWSAASPVQNGMDHCIYTVEIAFSTEIFGTFRQTVVFDLGC---EPVLMQRVMVDAASIEDLEHLLQA--RQQLLMTAKRWDSSCKTIVEFVPNENMDLERSLLTRYQIPLSADQLFTQSVLDKTLTRDNYQPRLHDLLYIEEIAQYKEVSKFNIKVNLQLVTSFMLTGISGGAKYAQNGQLFARFKLTETLSEDTLAGRLVMTKV-NSVLLLPVFKERMGQNQPAGAKERVYEALIEEKTKDYIFLRVCKECCDELGLVADQELQVELQFQLNRLPLCEMHYAL------DRVRDNSILFPDISLTP------TIPWSPNRQWDEQLDPRLNAKQKEAILAI----TTPLSINLPPVLIIGPYGTGKTFTLAQAVKHILK-QPESRVLICTHSNSAADLYIKDYLHPYVEAGNPHARPLRVYFRNRWVKTVHPLVQQYCLISGAH----------FTFQMPTRQDVERHRVVVVTL-----STSQYLCQLDLEPGIFTHILLDEAAQAMECETIMPLALAVKSTRVVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPSEYPCRILLCENYRSHEAIINYTSD-LFYEGKLMASGKQPPHKDFYPLTFFTARGE-----DVQEKNSTAYYNNAEVFEIVERVEEMRKKWPVSWGKLEEGSIGVVSPYADQVFRIRAELRKKRMSEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAIKRKEQLVEDSTEDLDYG-------FLSNYKLLNTAITRAQSLVAVVGDPIALCSVGRCRKFWETFISICHENHSL 1070          
BLAST of C2H2-type domain-containing protein vs. Ensembl Zebrafish
Match: helz (helicase with zinc finger [Source:NCBI gene;Acc:406550])

HSP 1 Score: 173.326 bits (438), Expect = 3.713e-43
Identity = 213/836 (25.48%), Postives = 363/836 (43.42%), Query Frame = 3
Query:  936 IYLRDDESRPFFKL--IKANQNQTVEHRSQLLTVC--------LKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQ---EVKYKNYVPFNMSETTC--RGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYES----RSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-------QKKLPILVLRKIDTSEIAL---PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDEL-TEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK--PTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS----------------------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            I L  D +RP F +  + A     +E +      C        +++    C+    I FS     T+RQ + FDL     E    + + VD  S E LE+L  +  R + ++T    +   K  V F  +E     R +L+   +      +  +  +  T+   NY   + D++ +EE+ Q   +SK   +  + +    M    S G   A +G+LF   K       D  A  +++  V N  +    FK  + + +        YE+    ++ + + +   K+  + + +   + ++  + F  +RL     H +L      D++  N +  P  +  P      TI + P    +E+       ++K  IL +    T+ +++   P ++ G +GTGKT   A+ V  IL+ + +S +LICT S SA +LY++ +                        K +  LV    LI  +H          F+ ++ T +    +RV + T+     S S +   L+ +  IF +I +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S  ++YE +L++  K  P     P+ FF +         V +K+  ++ N  EV  +VE V E+ K    S+   ++  I V SP+  QV  IR  LR K ++ V VE+  N+QG ++ V+F+STV +                       D D G       F SN  L+N  ++RA+  VAV+GD ++L +V   R  W TFI +C E  +L
Sbjct:  223 IALLYDANRPHFSIAAVSAGDASALEPQPVCPGGCQEWSAASPVQNGMDHCIYTVEIAFSTEIFGTFRQTVVFDLGC---EPVLMQRVMVDAASIEDLEHLLQA--RQQLLMTAKRWDSSCKTIVEFVPNENMDLERSLLTRYQIPLSADQLFTQSVLDKTLTRDNYQPRLHDLLYIEEIAQYKEVSKFNIKVNLQLVTSFMLTGISGGAKYAQNGQLFARFKLTETLSEDTLAGRLVMTKV-NSVLLLPVFKERMGQNQPAGAKERVYEALIEEKTKDYIFLRVCKECCDELGLVADQELQVELQFQLNRLPLCEMHYAL------DRVRDNSILFPDISLTP------TIPWSPNRQWDEQLDPRLNAKQKEAILAI----TTPLSINLPPVLIIGPYGTGKTFTLAQAVKHILK-QPESRVLICTHSNSAADLYIKDYLHPYVEAGNPHARPLRVYFRNRWVKTVHPLVQQYCLISGAH----------FTFQMPTRQDVERHRVVVVTL-----STSQYLCQLDLEPGIFTHILLDEAAQAMECETIMPLALAVKSTRVVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPSEYPCRILLCENYRSHEAIINYTSD-LFYEGKLMASGKQPPHKDFYPLTFFTARGE-----DVQEKNSTAYYNNAEVFEIVERVEEMRKKWPVSWGKLEEGSIGVVSPYADQVFRIRAELRKKRMSEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAIKRKEQLVEDSTEDLDYG-------FLSNYKLLNTAITRAQSLVAVVGDPIALCSVGRCRKFWETFISICHENHSL 1007          
BLAST of C2H2-type domain-containing protein vs. Ensembl Zebrafish
Match: helz2 (helicase with zinc finger 2, transcriptional coactivator [Source:ZFIN;Acc:ZDB-GENE-120920-1])

HSP 1 Score: 144.821 bits (364), Expect = 2.765e-34
Identity = 165/681 (24.23%), Postives = 287/681 (42.14%), Query Frame = 3
Query: 1269 VPFNMSETTCRGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSS-GLIPANDGKLFGDVKFG--------------RHHDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQI-FQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELT-----------------EEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLL------------KNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIV--VEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLT--TVNPTRDQWSTFIEMC 3161
            +PF  +E   R +L+       +++I     +   +   NY   M + +  EE     +LS+L   G + +KN L     G+  A+ G+LF  V                 RH   A R ++    +N Y         ++E E +       ++ S   V +  SK+    +N++N E  E  + F  +RL F   H +++++P+ DK+   P        + +  DE           NE+Q+     VL   D      P ++ G FGTGKT   A+   A+++ +  + ILICT + S+ +LY++  F +Y+    NG +L     + K  E     +D +T                 + +  + R+ ITT      SL+ FF  ++   + F++I +DEA+Q+LE +A+M        T+ + AGD  Q  P+L+  S+R    P  C  H +   L            K   I   E YR+   IV+++S   Y     +   +      P         +  E  +    +  F  E+ V++V  ++ +++    +  + D   + V S    QV  IR RLR   L R  VE   N+QG ++ V+ ISTV + D           F ++  ++N +++RA+  + V+GD  +L+          W  +IE C
Sbjct:  407 IPFVETEKAQRDLLNR------YQLIMMNQQMNGLINRENYKWSMHNFLYQEEKVVGELLSRLSLRGTVQLKNELSDDRFGMKWAHPGELFAAVPLSQPLTPDAPQGFIVKRH---AIRSLVRVVKNNEYCGP------IYEAEFLK------DAASETQVHLQLSKRCCAALNLQNGEEYEMEVQFQVNRLWFCEMHKAIDDLPRMDKVL--PDLKNAHLSISFQSDEG--------EFNEKQQAAMDFVLGVSDNRSSIPPLLIYGPFGTGKTRTLAKMAQALVQ-QPHNKILICTHTNSSADLYIKAHFHEYV---RNG-QLHARPLRIKAMEIKLASTDFITLQYCHLSREANCFEFPDKAVLDSTRIVITTT-----SLARFFNDMKLPENYFSHILIDEASQMLECEALMALSLAGNNTRVVLAGDHMQMGPKLF--SVR----PDKCSEHTLLNRLFYHYQAENSDVAKQSRIIFNENYRSTKDIVDFVSTHFYVGRSDVIKARGNVPSHPQQHALQFHHVRGECCLDPMSMSWFNAEQIVRVVHILQEIMKEWPQEWGAADPESVCVLSQGR-QVLEIRYRLRLLGLPRFTVENAENVQGKQFRVIVISTVHTKDSLLETDRTCLEFFNDMRVLNTIMTRAQSQIFVVGDAAALSCHQFGMCWRLWRAYIEEC 1039          
BLAST of C2H2-type domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-97a13.6 (si:dkey-97a13.6 [Source:ZFIN;Acc:ZDB-GENE-070912-617])

HSP 1 Score: 100.138 bits (248), Expect = 9.880e-21
Identity = 100/377 (26.53%), Postives = 170/377 (45.09%), Query Frame = 3
Query: 2130 AGELYMQIFQKYIPRLVNG---IKLIKSSHKRKGAEKNTIFSDELTEEI-----------------FTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSV-PIICRLHNIYK-----LLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISL--MKPTYQIVPMMFFD--SSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMC 3161
            + +LY++  + + P ++NG   +KL++    + G+    I +D++T +                    ++R+ ITT   A     +  P       F +I +DEA+Q+LE +A+M     +  T+ + AGD  Q  P+L++ +  K S   ++ RL + Y+     + K   I   E YR+   IV+++S   Y    + +   + P  ++ P++F        LS+ I        S+ N  EV  VV  V  LL +    +   D  +I V S    QV  IR  LR K    V V+  +NIQG ++ V+ I+TV + D    +    P F  +   +N  ++RA+  V VIGD  +L         W  +IE C
Sbjct:    2 SADLYVR--EHFHPYIINGHPTLKLLRIKANKGGSA--IIATDDITRKYCLCSRDGQSFILPARSDLESHRIIITTTSIARHLHELKLP----KGFFTHILIDEASQMLEGEALMALGLADKHTRVVLAGDHMQMAPKLFSVTDDKRSEHTLLNRLFHYYQDQSINIAKKSRIIFNENYRSTTEIVDFVSTYFYVSDGIKARGDVHPHPRLKPLIFHHVRGECHLSSTITS-----TSWLNYAEVNSVVNMVQVLLTDWPMEWGDKDPKQICVLSEG-QQVAAIRIHLRRKGFYGVSVQNLANIQGKQFRVIIITTVHTRDKLLQLDSSCPEFFDDIRALNTALTRAQSLVVVIGDAGALCCFGKCSKVWRAYIEHC 364          

HSP 2 Score: 58.9214 bits (141), Expect = 3.770e-8
Identity = 69/279 (24.73%), Postives = 118/279 (42.29%), Query Frame = 3
Query: 2334 PILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKT-KFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQIV-----------PMMFFD-SSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPI-------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSL 3110
            P L+K      I +DE A   E   ++     ++K  K +  GD  Q RP + N  +R+  +       ++++   +  I L   YR H  I  + S+A YY   L ++++    ++            ++F D     +   +     +  S  N  EVK  VE  ++L+       +   IL  SP+ AQV  IR+RL    L    V   +  QG E+  V +S V S   D   P+        H  F  + N IN+ ++RA+  + ++G++  L
Sbjct: 1891 PNLKKTLSARQILIDECAMATEPQTLV--PLVSFKPEKVVLLGDHKQLRPIVKNNHVRRLGM-----TRSLFERYMDRAIMLDTQYRMHEEICKFPSEA-YYNDMLKTVVRERTSVLNAETEGRRQSKRILFGDIRGEEIGLVVSTARGNENSKANFDEVKKAVEICIQLVTVGRVRPEDIAIL--SPYNAQVAQIRERLSDFELKGFTVTTITKSQGSEWQYVILSIVRSCPSDEIEPMPSREWLSKHIGFVGDENQINVGITRAQVGLCILGNQAVL 2159          
BLAST of C2H2-type domain-containing protein vs. Ensembl Zebrafish
Match: mov10a (Mov10 RISC complex RNA helicase a [Source:ZFIN;Acc:ZDB-GENE-091230-8])

HSP 1 Score: 85.1149 bits (209), Expect = 3.580e-16
Identity = 109/458 (23.80%), Postives = 187/458 (40.83%), Query Frame = 3
Query: 1944 NEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYI--------------PRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAI--MVYQFGNYKTKFIFAGDIFQTRPELYN--KSLRKFSVPIICRLHNIYKLLKN-----------YTITLREVYRTHPAIVNYLSQAIYYETQLISLMKP-------TYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSF----SFDQSKILVCSPFYAQVKLIRDRLRS----KSLNRVVVEQPSNIQGCEYDVVFISTVLSS------DDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDE 3167
            N EQK     V   +  S    P+++ G  GTGKT+   E +  + +++ +S IL C  S SA +L  +    ++              PR V   KL+K S+  +  +   + S    +E      + + T+  A   +S        +  F +IF+DEA Q +E + I  +       K + + AGD  Q  P L +    L      ++ RL     L +            +   L   YR+HPAI+  +   ++YE +L              ++ +P   F             + +  SF N  E++++V  +  L++ +          + I + +P+  QV+ IR  L +    K    + V      QG E  V+ +STV SS      D D  I      F SN    N+ ++RAK  + V+G+ + L+  +PT   W  FI+ C++
Sbjct:  517 NPEQK---AAVQHILSGSSRPAPYLIFGPPGTGKTVTVVEAIKQVDKSKAQSHILACAPSNSACDLLCERLLGHVDAHRIYRLCAPSRDPRTVPQ-KLLKHSNWNEAQDSFLLPS----KETLIGYSIIVVTLVTAGRLVSGGV----AMGHFTHIFIDEAGQAVEPECIIGIAGLLDPLKGQLVLAGDPQQLGPVLRSPLAQLHGLGQSLLERLMKRNALYQKSQDDNSKYDSRFVTKLLRNYRSHPAILK-IPNELFYENELQVFANQMEREAFCQWEHLPRKGFPVVFHGVMGKDEREANSPSFFNVTEIEVIVNYLNNLMQTQGKKGLPKLGPNDIGIIAPYRKQVEKIRKALNTVGELKKWKDIKVGSVEEFQGQERKVIIVSTVRSSVNYVKMDQDFNI-----GFLSNEKRFNVAMTRAKGLLIVVGNPVILSK-DPT---WQKFIQYCEQ 952          
BLAST of C2H2-type domain-containing protein vs. Ensembl Xenopus
Match: frmd7 (FERM domain containing 7 [Source:Xenbase;Acc:XB-GENE-6041331])

HSP 1 Score: 175.252 bits (443), Expect = 1.124e-43
Identity = 204/770 (26.49%), Postives = 351/770 (45.58%), Query Frame = 3
Query: 1056 CVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTC--RGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPK----YDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            C+ +  I F+     T+RQ + FD      E    + I VD  S E LE L  + ++   ++T   ++    K  V F  +ETT   R +LS   +      +  +  +  ++   NY   + D++ +EE+ Q   +SK   +  + +    M    S G   A +G+LFG  K       D  A  +++  V+  YV    K +    +      +    E ++ + + +   K   + + +K    ++  + F  +RL     H +L+ V      +  LS  P   P+     + E     +  P+  LN +QK+  IL +    + ++  P ++ G +GTGKT   A+ V  IL+ + ++ +LICT S SA +LY++ +                        K +  +V+   LI S+H        ++F     E+I   +RV + T+     S S +   L+ +   F +I +DEAAQ +E + IM     +  T+ + AGD  Q  P +Y++  R+    V ++ RL+ +Y +     I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D+  I V +P+  QV  IR  LR K L+ + VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E  +L
Sbjct:  279 CIYKVVIAFTTEIFGTFRQTVVFDF---GAEPVLMQRIMVDAASTEDLEYLMHARQQ---LLTTAKRWDSMSKTIVEFEPNETTEMERSLLSRYQIPLSADQLFTQSVLDKSLTKCNYQARLHDLLYIEEIAQYKEVSKFNIKVQLQLVASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYVLPVTKERSVQSQGTKEKVYEAVIEEKTKDYIFLRICKDCCDELKLKPDREMQVELQFQLNRLPLCEMHYALDRVKDNSILFPDLSMTPPI-PWSPNRQWDE-----LLDPR--LNAKQKEA-ILAITTPLSVQLP-PILIIGPYGTGKTFTLAQAVKHILKQQ-ETRVLICTHSNSAADLYIKDYLHPYVETGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTH--------SVFQMPQKEDIL-QHRVVVVTL-----STSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALASKSTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYELYPVDFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDEGSIGVVTPYADQVFRIRAELRKKRLSEISVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKRKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWEQFISICHENKSL 1011          
BLAST of C2H2-type domain-containing protein vs. Ensembl Xenopus
Match: frmd7 (FERM domain containing 7 [Source:Xenbase;Acc:XB-GENE-6041331])

HSP 1 Score: 174.096 bits (440), Expect = 2.577e-43
Identity = 204/770 (26.49%), Postives = 351/770 (45.58%), Query Frame = 3
Query: 1056 CVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTC--RGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPK----YDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            C+ +  I F+     T+RQ + FD      E    + I VD  S E LE L  + ++   ++T   ++    K  V F  +ETT   R +LS   +      +  +  +  ++   NY   + D++ +EE+ Q   +SK   +  + +    M    S G   A +G+LFG  K       D  A  +++  V+  YV    K +    +      +    E ++ + + +   K   + + +K    ++  + F  +RL     H +L+ V      +  LS  P   P+     + E     +  P+  LN +QK+  IL +    + ++  P ++ G +GTGKT   A+ V  IL+ + ++ +LICT S SA +LY++ +                        K +  +V+   LI S+H        ++F     E+I   +RV + T+     S S +   L+ +   F +I +DEAAQ +E + IM     +  T+ + AGD  Q  P +Y++  R+    V ++ RL+ +Y +     I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D+  I V +P+  QV  IR  LR K L+ + VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E  +L
Sbjct:  329 CIYKVVIAFTTEIFGTFRQTVVFDF---GAEPVLMQRIMVDAASTEDLEYLMHARQQ---LLTTAKRWDSMSKTIVEFEPNETTEMERSLLSRYQIPLSADQLFTQSVLDKSLTKCNYQARLHDLLYIEEIAQYKEVSKFNIKVQLQLVASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYVLPVTKERSVQSQGTKEKVYEAVIEEKTKDYIFLRICKDCCDELKLKPDREMQVELQFQLNRLPLCEMHYALDRVKDNSILFPDLSMTPPI-PWSPNRQWDE-----LLDPR--LNAKQKEA-ILAITTPLSVQLP-PILIIGPYGTGKTFTLAQAVKHILKQQ-ETRVLICTHSNSAADLYIKDYLHPYVETGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTH--------SVFQMPQKEDIL-QHRVVVVTL-----STSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALASKSTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYELYPVDFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDEGSIGVVTPYADQVFRIRAELRKKRLSEISVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKRKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWEQFISICHENKSL 1061          
BLAST of C2H2-type domain-containing protein vs. Ensembl Xenopus
Match: frmd7 (FERM domain containing 7 [Source:Xenbase;Acc:XB-GENE-6041331])

HSP 1 Score: 173.326 bits (438), Expect = 5.157e-43
Identity = 204/770 (26.49%), Postives = 351/770 (45.58%), Query Frame = 3
Query: 1056 CVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTC--RGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPK----YDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            C+ +  I F+     T+RQ + FD      E    + I VD  S E LE L  + ++   ++T   ++    K  V F  +ETT   R +LS   +      +  +  +  ++   NY   + D++ +EE+ Q   +SK   +  + +    M    S G   A +G+LFG  K       D  A  +++  V+  YV    K +    +      +    E ++ + + +   K   + + +K    ++  + F  +RL     H +L+ V      +  LS  P   P+     + E     +  P+  LN +QK+  IL +    + ++  P ++ G +GTGKT   A+ V  IL+ + ++ +LICT S SA +LY++ +                        K +  +V+   LI S+H        ++F     E+I   +RV + T+     S S +   L+ +   F +I +DEAAQ +E + IM     +  T+ + AGD  Q  P +Y++  R+    V ++ RL+ +Y +     I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D+  I V +P+  QV  IR  LR K L+ + VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E  +L
Sbjct:  338 CIYKVVIAFTTEIFGTFRQTVVFDF---GAEPVLMQRIMVDAASTEDLEYLMHARQQ---LLTTAKRWDSMSKTIVEFEPNETTEMERSLLSRYQIPLSADQLFTQSVLDKSLTKCNYQARLHDLLYIEEIAQYKEVSKFNIKVQLQLVASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYVLPVTKERSVQSQGTKEKVYEAVIEEKTKDYIFLRICKDCCDELKLKPDREMQVELQFQLNRLPLCEMHYALDRVKDNSILFPDLSMTPPI-PWSPNRQWDE-----LLDPR--LNAKQKEA-ILAITTPLSVQLP-PILIIGPYGTGKTFTLAQAVKHILKQQ-ETRVLICTHSNSAADLYIKDYLHPYVETGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTH--------SVFQMPQKEDIL-QHRVVVVTL-----STSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALASKSTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYELYPVDFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDEGSIGVVTPYADQVFRIRAELRKKRLSEISVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKRKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWEQFISICHENKSL 1070          
BLAST of C2H2-type domain-containing protein vs. Ensembl Xenopus
Match: frmd7 (FERM domain containing 7 [Source:Xenbase;Acc:XB-GENE-6041331])

HSP 1 Score: 172.94 bits (437), Expect = 6.749e-43
Identity = 204/770 (26.49%), Postives = 351/770 (45.58%), Query Frame = 3
Query: 1056 CVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTC--RGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPK----YDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            C+ +  I F+     T+RQ + FD      E    + I VD  S E LE L  + ++   ++T   ++    K  V F  +ETT   R +LS   +      +  +  +  ++   NY   + D++ +EE+ Q   +SK   +  + +    M    S G   A +G+LFG  K       D  A  +++  V+  YV    K +    +      +    E ++ + + +   K   + + +K    ++  + F  +RL     H +L+ V      +  LS  P   P+     + E     +  P+  LN +QK+  IL +    + ++  P ++ G +GTGKT   A+ V  IL+ + ++ +LICT S SA +LY++ +                        K +  +V+   LI S+H        ++F     E+I   +RV + T+     S S +   L+ +   F +I +DEAAQ +E + IM     +  T+ + AGD  Q  P +Y++  R+    V ++ RL+ +Y +     I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D+  I V +P+  QV  IR  LR K L+ + VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E  +L
Sbjct:  329 CIYKVVIAFTTEIFGTFRQTVVFDF---GAEPVLMQRIMVDAASTEDLEYLMHARQQ---LLTTAKRWDSMSKTIVEFEPNETTEMERSLLSRYQIPLSADQLFTQSVLDKSLTKCNYQARLHDLLYIEEIAQYKEVSKFNIKVQLQLVASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYVLPVTKERSVQSQGTKEKVYEAVIEEKTKDYIFLRICKDCCDELKLKPDREMQVELQFQLNRLPLCEMHYALDRVKDNSILFPDLSMTPPI-PWSPNRQWDE-----LLDPR--LNAKQKEA-ILAITTPLSVQLP-PILIIGPYGTGKTFTLAQAVKHILKQQ-ETRVLICTHSNSAADLYIKDYLHPYVETGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTH--------SVFQMPQKEDIL-QHRVVVVTL-----STSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALASKSTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYELYPVDFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDEGSIGVVTPYADQVFRIRAELRKKRLSEISVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKRKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWEQFISICHENKSL 1061          
BLAST of C2H2-type domain-containing protein vs. Ensembl Xenopus
Match: frmd7 (FERM domain containing 7 [Source:Xenbase;Acc:XB-GENE-6041331])

HSP 1 Score: 172.555 bits (436), Expect = 7.349e-43
Identity = 204/770 (26.49%), Postives = 351/770 (45.58%), Query Frame = 3
Query: 1056 CVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTC--RGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPK----YDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            C+ +  I F+     T+RQ + FD      E    + I VD  S E LE L  + ++   ++T   ++    K  V F  +ETT   R +LS   +      +  +  +  ++   NY   + D++ +EE+ Q   +SK   +  + +    M    S G   A +G+LFG  K       D  A  +++  V+  YV    K +    +      +    E ++ + + +   K   + + +K    ++  + F  +RL     H +L+ V      +  LS  P   P+     + E     +  P+  LN +QK+  IL +    + ++  P ++ G +GTGKT   A+ V  IL+ + ++ +LICT S SA +LY++ +                        K +  +V+   LI S+H        ++F     E+I   +RV + T+     S S +   L+ +   F +I +DEAAQ +E + IM     +  T+ + AGD  Q  P +Y++  R+    V ++ RL+ +Y +     I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D+  I V +P+  QV  IR  LR K L+ + VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E  +L
Sbjct:  345 CIYKVVIAFTTEIFGTFRQTVVFDF---GAEPVLMQRIMVDAASTEDLEYLMHARQQ---LLTTAKRWDSMSKTIVEFEPNETTEMERSLLSRYQIPLSADQLFTQSVLDKSLTKCNYQARLHDLLYIEEIAQYKEVSKFNIKVQLQLVASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYVLPVTKERSVQSQGTKEKVYEAVIEEKTKDYIFLRICKDCCDELKLKPDREMQVELQFQLNRLPLCEMHYALDRVKDNSILFPDLSMTPPI-PWSPNRQWDE-----LLDPR--LNAKQKEA-ILAITTPLSVQLP-PILIIGPYGTGKTFTLAQAVKHILKQQ-ETRVLICTHSNSAADLYIKDYLHPYVETGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTH--------SVFQMPQKEDIL-QHRVVVVTL-----STSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALASKSTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYELYPVDFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDEGSIGVVTPYADQVFRIRAELRKKRLSEISVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKRKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWEQFISICHENKSL 1077          
BLAST of C2H2-type domain-containing protein vs. Ensembl Mouse
Match: Helz (helicase with zinc finger domain [Source:MGI Symbol;Acc:MGI:1925705])

HSP 1 Score: 172.94 bits (437), Expect = 4.832e-43
Identity = 208/771 (26.98%), Postives = 345/771 (44.75%), Query Frame = 3
Query: 1059 VVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTCRGVLSEELLGSIFKIIP-------NRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNN--------LNEEQKKLPILVLRKIDTSEIALPFILN-GAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIF----------QKYIPRLVNGIKLIKSSHKRKG-----AEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            V + GI F+     T+RQ I FD      E    + + +D  S E LE L  +    + ++T   ++    K  V F  +ETT    L + LL  I   IP        +  +  ++   NY   + D++ +EE+ Q   +S+   +  + I    M    S G   A +G+LFG  K       D  A  +++  V+  Y+    K K+   +      +    E ++ + V +  S++  E ++++    ++  + F  +RL     H +L      D++  N +  P  +  P      TI + P           LN +QK+  + +   +    I LP +L  G +GTGKT   A+    IL+ +  S ILICT S SA +LY++ +          Q    R+    + +K+ H         +   + F     E+I   +RV + T+     S S +   L+ +   F ++ +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D   I V +P+  QV  IR  LR K L+ V VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E  +L
Sbjct:  346 VYKVGIAFNTEIFGTFRQTIVFDFGL---EPVLMQRVMIDAASTEDLEYLMHA---KRQLVTTAKRWDSSSKTIVDFEPNETT---DLEKSLL--IRYQIPLSADQLFTQSVLDKSLTKTNYQARLHDLLYIEEIAQYKEVSRFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTRVNAVYLLPVPKEKLVQSQGTKEKVYEATIEEKTKDYVFLRISRECCEELSLRPDCDIQVELQFQLNRLPLCEMHYAL------DRIKDNAVLFPDISMTP------TIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLS---IQLPPVLIIGPYGTGKTFTLAQAAKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTQSTFQMPQKEDIL-KHRVVVVTL-----STSQYLCQLDLEPGFFTHVLLDEAAQAMECETIMPLALATKNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPVALCSIGRCRKFWERFIALCHENHSL 1078          
BLAST of C2H2-type domain-containing protein vs. Ensembl Mouse
Match: Helz (helicase with zinc finger domain [Source:MGI Symbol;Acc:MGI:1925705])

HSP 1 Score: 171.4 bits (433), Expect = 1.304e-42
Identity = 207/771 (26.85%), Postives = 346/771 (44.88%), Query Frame = 3
Query: 1059 VVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTCRGVLSEELLGSIFKIIP-------NRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNN--------LNEEQKKLPILVLRKIDTSEIALPFILN-GAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIF----------QKYIPRLVNGIKLIKSSHKRKG-----AEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            V + GI F+     T+RQ I FD      E    + + +D  S E LE L  +    + ++T   ++    K  V F  +ETT    L + LL  I   IP        +  +  ++   NY   + D++ +EE+ Q   +S+   +  + I    M    S G   A +G+LFG  K       D  A  +++  V+  Y+    K K+   +      +    E ++ + V +  S++  E ++++    ++  + F  +RL     H +L      D++  N +  P  +  P      TI + P           LN +QK+  + +   +    I LP +L  G +GTGKT   A+    IL+ + ++ ILICT S SA +LY++ +          Q    R+    + +K+ H         +   + F     E+I   +RV + T+     S S +   L+ +   F ++ +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D   I V +P+  QV  IR  LR K L+ V VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E  +L
Sbjct:  346 VYKVGIAFNTEIFGTFRQTIVFDFGL---EPVLMQRVMIDAASTEDLEYLMHA---KRQLVTTAKRWDSSSKTIVDFEPNETT---DLEKSLL--IRYQIPLSADQLFTQSVLDKSLTKTNYQARLHDLLYIEEIAQYKEVSRFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTRVNAVYLLPVPKEKLVQSQGTKEKVYEATIEEKTKDYVFLRISRECCEELSLRPDCDIQVELQFQLNRLPLCEMHYAL------DRIKDNAVLFPDISMTP------TIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLS---IQLPPVLIIGPYGTGKTFTLAQAAKHILQQQ-ETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTQSTFQMPQKEDIL-KHRVVVVTL-----STSQYLCQLDLEPGFFTHVLLDEAAQAMECETIMPLALATKNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPVALCSIGRCRKFWERFIALCHENHSL 1077          
BLAST of C2H2-type domain-containing protein vs. Ensembl Mouse
Match: Helz (helicase with zinc finger domain [Source:MGI Symbol;Acc:MGI:1925705])

HSP 1 Score: 169.088 bits (427), Expect = 7.702e-42
Identity = 207/771 (26.85%), Postives = 346/771 (44.88%), Query Frame = 3
Query: 1059 VVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTCRGVLSEELLGSIFKIIP-------NRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNN--------LNEEQKKLPILVLRKIDTSEIALPFILN-GAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIF----------QKYIPRLVNGIKLIKSSHKRKG-----AEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            V + GI F+     T+RQ I FD      E    + + +D  S E LE L  +    + ++T   ++    K  V F  +ETT    L + LL  I   IP        +  +  ++   NY   + D++ +EE+ Q   +S+   +  + I    M    S G   A +G+LFG  K       D  A  +++  V+  Y+    K K+   +      +    E ++ + V +  S++  E ++++    ++  + F  +RL     H +L      D++  N +  P  +  P      TI + P           LN +QK+  + +   +    I LP +L  G +GTGKT   A+    IL+ + ++ ILICT S SA +LY++ +          Q    R+    + +K+ H         +   + F     E+I   +RV + T+     S S +   L+ +   F ++ +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D   I V +P+  QV  IR  LR K L+ V VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E  +L
Sbjct:  346 VYKVGIAFNTEIFGTFRQTIVFDFGL---EPVLMQRVMIDAASTEDLEYLMHA---KRQLVTTAKRWDSSSKTIVDFEPNETT---DLEKSLL--IRYQIPLSADQLFTQSVLDKSLTKTNYQARLHDLLYIEEIAQYKEVSRFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTRVNAVYLLPVPKEKLVQSQGTKEKVYEATIEEKTKDYVFLRISRECCEELSLRPDCDIQVELQFQLNRLPLCEMHYAL------DRIKDNAVLFPDISMTP------TIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLS---IQLPPVLIIGPYGTGKTFTLAQAAKHILQQQ-ETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTQSTFQMPQKEDIL-KHRVVVVTL-----STSQYLCQLDLEPGFFTHVLLDEAAQAMECETIMPLALATKNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPVALCSIGRCRKFWERFIALCHENHSL 1077          
BLAST of C2H2-type domain-containing protein vs. Ensembl Mouse
Match: Helz2 (helicase with zinc finger 2, transcriptional coactivator [Source:MGI Symbol;Acc:MGI:2385169])

HSP 1 Score: 126.716 bits (317), Expect = 1.059e-28
Identity = 152/640 (23.75%), Postives = 270/640 (42.19%), Query Frame = 3
Query: 1356 DWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSS-GLIPANDGKLFGDVKFGRH--HDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQK-KLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYM-QIFQKYIPR---LVNGIKLIKSSHKRKGAEKNTIFSDELTEEI----------FTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELY----NKSLRKFSVPIICRLHNIY-----KLLKNYTITLREVYRTHPAIVNYLSQAIYYET----QLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDD--DSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDE 3167
            DW    +   NY   M   +  EE  Q+ +++KL  +G +++K  L T + G++ A  G L+  V F      D     ++ + VS   VA             V   R E  + S   + +    +    + ++  +     + F    + F   H ++      D L    L  P    LP           P    N +QK  + ++  R+ + ++   P ++ G FGTGKT   A   + +++ +  + +LICT + SA ++Y+ + F  Y+         ++++ +    +  +  T+    LTE+             ++R+ +TT   A +       +      F++IF+DEAAQ+LE +A++   +    T+ + AGD  Q  P L+    +KS R     ++ RL   Y     K+ +   I   E YR+  AI+N++S   Y       Q    +    Q  P+MF   + +        D  + S+ N  EV  VVE V E+       +   +Q  I   S   AQV  +R  LR ++L  V V     + G E+ VV +S+V + +     G P     F +   ++N V++RA+  +  +GD ++L +    R+ W +FI  C E
Sbjct:  579 DW--GPISRSNYRQRMHKFLYEEEAAQQQLVAKLAMKGQVSLKTALETPALGMLFAPPGALYAKVPFHSSLLPDTDQGFLLSRAVSTALVA-----PVPAPNSTVYQVRLEARASSDHALWLLLPARCCMALGLQAQDSPILEVQFQIDPMTFRFWHQAV------DALLEEHLVVP---DLPACTLPHPWPTPPSFRGNHKQKLAVGLIAGRRPEGTKHIPPLLIYGPFGTGKTYTLAMAALEVVQ-QPHTKVLICTHTNSAADIYIREYFHDYVSSGHPEATPLRVMYADRPPRQTDPTTLQYCCLTEDRQAFRPPTGPELVHHRLVVTTTSQARE-------LQVPAGFFSHIFIDEAAQMLECEALIPLSYALSLTRVVLAGDHMQVTPRLFSVPRDKSARH---TLLHRLFLYYQQEAHKIAQQSRIIFHENYRSTAAIINFVSHHFYLAKGNPIQASGKVPRHPQHYPLMFCHVAGSPEQ-----DMSMTSWLNSAEVTQVVEKVREIYNTWPHCWGPREQRHICAVS-HGAQVSALRQELRRRNLGEVSVGSFEILPGREFRVVVLSSVHNRNSLLSPGAPT--SEFFTEPRVLNTVMTRAQSQLVAVGDAVALCSSGACRNLWRSFIRECIE 1183          
BLAST of C2H2-type domain-containing protein vs. Ensembl Mouse
Match: Helz2 (helicase with zinc finger 2, transcriptional coactivator [Source:MGI Symbol;Acc:MGI:2385169])

HSP 1 Score: 126.716 bits (317), Expect = 1.063e-28
Identity = 152/640 (23.75%), Postives = 270/640 (42.19%), Query Frame = 3
Query: 1356 DWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSS-GLIPANDGKLFGDVKFGRH--HDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQK-KLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYM-QIFQKYIPR---LVNGIKLIKSSHKRKGAEKNTIFSDELTEEI----------FTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELY----NKSLRKFSVPIICRLHNIY-----KLLKNYTITLREVYRTHPAIVNYLSQAIYYET----QLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDD--DSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDE 3167
            DW    +   NY   M   +  EE  Q+ +++KL  +G +++K  L T + G++ A  G L+  V F      D     ++ + VS   VA             V   R E  + S   + +    +    + ++  +     + F    + F   H ++      D L    L  P    LP           P    N +QK  + ++  R+ + ++   P ++ G FGTGKT   A   + +++ +  + +LICT + SA ++Y+ + F  Y+         ++++ +    +  +  T+    LTE+             ++R+ +TT   A +       +      F++IF+DEAAQ+LE +A++   +    T+ + AGD  Q  P L+    +KS R     ++ RL   Y     K+ +   I   E YR+  AI+N++S   Y       Q    +    Q  P+MF   + +        D  + S+ N  EV  VVE V E+       +   +Q  I   S   AQV  +R  LR ++L  V V     + G E+ VV +S+V + +     G P     F +   ++N V++RA+  +  +GD ++L +    R+ W +FI  C E
Sbjct:  579 DW--GPISRSNYRQRMHKFLYEEEAAQQQLVAKLAMKGQVSLKTALETPALGMLFAPPGALYAKVPFHSSLLPDTDQGFLLSRAVSTALVA-----PVPAPNSTVYQVRLEARASSDHALWLLLPARCCMALGLQAQDSPILEVQFQIDPMTFRFWHQAV------DALLEEHLVVP---DLPACTLPHPWPTPPSFRGNHKQKLAVGLIAGRRPEGTKHIPPLLIYGPFGTGKTYTLAMAALEVVQ-QPHTKVLICTHTNSAADIYIREYFHDYVSSGHPEATPLRVMYADRPPRQTDPTTLQYCCLTEDRQAFRPPTGPELVHHRLVVTTTSQARE-------LQVPAGFFSHIFIDEAAQMLECEALIPLSYALSLTRVVLAGDHMQVTPRLFSVPRDKSARH---TLLHRLFLYYQQEAHKIAQQSRIIFHENYRSTAAIINFVSHHFYLAKGNPIQASGKVPRHPQHYPLMFCHVAGSPEQ-----DMSMTSWLNSAEVTQVVEKVREIYNTWPHCWGPREQRHICAVS-HGAQVSALRQELRRRNLGEVSVGSFEILPGREFRVVVLSSVHNRNSLLSPGAPT--SEFFTEPRVLNTVMTRAQSQLVAVGDAVALCSSGACRNLWRSFIRECIE 1183          
BLAST of C2H2-type domain-containing protein vs. UniProt/SwissProt
Match: sp|P42694|HELZ_HUMAN (Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2)

HSP 1 Score: 177.948 bits (450), Expect = 8.959e-44
Identity = 211/779 (27.09%), Postives = 352/779 (45.19%), Query Frame = 3
Query: 1059 VVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTCRGVLSEELLGSIFKIIP-------NRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-------QKKLPILVLRKIDTSEIAL---PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            V + GI F+     T+RQ I FD      E    + + +D  S E LE L  + ++   ++T   ++    K  + F  +ETT    L + LL  I   IP        +  +  ++   NY + + D++ +EE+ Q   +SK   +  + I    M    S G   A +G+LFG  K       D  A  +++  V+  Y+    K K+   +      +    E ++ E + +  S++  E +N++     +  + F  +RL     H +L      D++  N +  P  +  P      TI + P    +E+       ++K  +L +    T+ +A+   P ++ G +GTGKT   A+ V  IL+ + ++ ILICT S SA +LY++ +                        K +  +V+   LI S+H        + F     E+I   +RV + T+ N +  L      LE    F +I +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D   I V +P+  QV  IR  LR K L+ V VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E ++L
Sbjct:  346 VYKVGIAFNTEIFGTFRQTIVFDFGL---EPVLMQRVMIDAASTEDLEYLMHAKQQ---LVTTAKRWDSSSKTIIDFEPNETT---DLEKSLL--IRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYAL------DRIKDNGVLFPDISMTP------TIPWSPNRQWDEQLDPRLNAKQKEAVLAI----TTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQ-ETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAH--------STFQMPQKEDIL-KHRVVVVTL-NTSQYLCQL--DLEP-GFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL 1077          
BLAST of C2H2-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6NYU2|HELZ_DANRE (Probable helicase with zinc finger domain OS=Danio rerio OX=7955 GN=helz PE=2 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 4.721e-42
Identity = 212/836 (25.36%), Postives = 363/836 (43.42%), Query Frame = 3
Query:  936 IYLRDDESRPFFKL--IKANQNQTVEHRSQLLTVC--------LKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQ---EVKYKNYVPFNMSETTC--RGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYES----RSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-------QKKLPILVLRKIDTSEIAL---PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQ-----------------------KYIPRLVNGIKLIKSSHKRKGAEKNTIFSDEL-TEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK--PTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS----------------------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            I L  D +RP F +  + A     +E +      C        +++    C+    I FS     T+RQ + FDL     E    + + VD  S E LE+L  +  R + ++T    +   K  V F  +E     R +L+   +      +  +  +  T+   NY   + D++ +EE+ Q   ++K   +  + +    M    S G   A +G+LF   K       D  A  +++  V N  +    FK  + + +        YE+    ++ + + +   K+  + + +   + ++  + F  +RL     H +L      D++  N +  P  +  P      TI + P    +E+       ++K  IL +    T+ +++   P ++ G +GTGKT   A+ V  IL+ + +S +LICT S SA +LY++ +                        K +  LV    LI  +H          F+ ++ T +    +RV + T+     S S +   L+ +  IF +I +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S  ++YE +L++  K  P     P+ FF +         V +K+  ++ N  EV  +VE V E+ K    S+   ++  I V SP+  QV  IR  LR K ++ V VE+  N+QG ++ V+F+STV +                       D D G       F SN  L+N  ++RA+  VAV+GD ++L +V   R  W TFI +C E  +L
Sbjct:  286 IALLYDANRPHFSIAAVSAGDASALEPQPVCPGGCQEWSAASPVQNGMDHCIYTVEIAFSTEIFGTFRQTVVFDLGC---EPVLMQRVMVDAASIEDLEHLLQA--RQQLLMTAKRWDSSCKTIVEFVPNENMDLERSLLTRYQIPLSADQLFTQSVLDKTLTRDNYQPRLHDLLYIEEIAQYKEVTKFNIKVNLQLVTSFMLTGISGGAKYAQNGQLFARFKLTETLSEDTLAGRLVMTKV-NSVLLLPVFKERMGQNQPAGAKERVYEALIEEKTKDYIFLRVCKECCDELGLVADQELQVELQFQLNRLPLCEMHYAL------DRVRDNSILFPDISLTP------TIPWSPNRQWDEQLDPRLNAKQKEAILAI----TTPLSINLPPVLIIGPYGTGKTFTLAQAVKHILK-QPESRVLICTHSNSAADLYIKDYLHPYVEAGNPHARPLRVYFRNRWVKTVHPLVQQYCLISGAH----------FTFQMPTRQDVERHRVVVVTL-----STSQYLCQLDLEPGIFTHILLDEAAQAMECETIMPLALAVKSTRVVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPSEYPCRILLCENYRSHEAIINYTSD-LFYEGKLMASGKQPPHKDFYPLTFFTARGE-----DVQEKNSTAYYNNAEVFEIVERVEEMRKKWPVSWGKLEEGSIGVVSPYADQVFRIRAELRKKRMSEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAIKRKEQLVEDSTEDLDYG-------FLSNYKLLNTAITRAQSLVAVVGDPIALCSVGRCRKFWETFISICHENHSL 1070          
BLAST of C2H2-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6DFV5|HELZ_MOUSE (Probable helicase with zinc finger domain OS=Mus musculus OX=10090 GN=Helz PE=1 SV=2)

HSP 1 Score: 169.088 bits (427), Expect = 5.387e-41
Identity = 207/771 (26.85%), Postives = 346/771 (44.88%), Query Frame = 3
Query: 1059 VVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKY----KNYVPFNMSETTCRGVLSEELLGSIFKIIP-------NRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGR--HHDQAAREIIIKCVSNCYV-AFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNN--------LNEEQKKLPILVLRKIDTSEIALPFILN-GAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIF----------QKYIPRLVNGIKLIKSSHKRKG-----AEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPI-------------LHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            V + GI F+     T+RQ I FD      E    + + +D  S E LE L  +    + ++T   ++    K  V F  +ETT    L + LL  I   IP        +  +  ++   NY   + D++ +EE+ Q   +S+   +  + I    M    S G   A +G+LFG  K       D  A  +++  V+  Y+    K K+   +      +    E ++ + V +  S++  E ++++    ++  + F  +RL     H +L      D++  N +  P  +  P      TI + P           LN +QK+  + +   +    I LP +L  G +GTGKT   A+    IL+ + ++ ILICT S SA +LY++ +          Q    R+    + +K+ H         +   + F     E+I   +RV + T+     S S +   L+ +   F ++ +DEAAQ +E + IM        T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+ ++YE +L++  K P ++   P+ FF +         V +K+  +F N  EV  VVE V EL +    ++   D   I V +P+  QV  IR  LR K L+ V VE+  N+QG ++ V+F+STV +         PI             L   F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FI +C E  +L
Sbjct:  346 VYKVGIAFNTEIFGTFRQTIVFDFGL---EPVLMQRVMIDAASTEDLEYLMHA---KRQLVTTAKRWDSSSKTIVDFEPNETT---DLEKSLL--IRYQIPLSADQLFTQSVLDKSLTKTNYQARLHDLLYIEEIAQYKEVSRFNLKVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTRVNAVYLLPVPKEKLVQSQGTKEKVYEATIEEKTKDYVFLRISRECCEELSLRPDCDIQVELQFQLNRLPLCEMHYAL------DRIKDNAVLFPDISMTP------TIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLS---IQLPPVLIIGPYGTGKTFTLAQAAKHILQQQ-ETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTQSTFQMPQKEDIL-KHRVVVVTL-----STSQYLCQLDLEPGFFTHVLLDEAAQAMECETIMPLALATKNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPAHKDFYPLTFFTARGE-----DVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPVALCSIGRCRKFWERFIALCHENHSL 1077          
BLAST of C2H2-type domain-containing protein vs. UniProt/SwissProt
Match: sp|E9QAM5|HELZ2_MOUSE (Helicase with zinc finger domain 2 OS=Mus musculus OX=10090 GN=Helz2 PE=1 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 7.434e-28
Identity = 152/640 (23.75%), Postives = 270/640 (42.19%), Query Frame = 3
Query: 1356 DWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSS-GLIPANDGKLFGDVKFGRH--HDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQK-KLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYM-QIFQKYIPR---LVNGIKLIKSSHKRKGAEKNTIFSDELTEEI----------FTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELY----NKSLRKFSVPIICRLHNIY-----KLLKNYTITLREVYRTHPAIVNYLSQAIYYET----QLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDD--DSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDE 3167
            DW    +   NY   M   +  EE  Q+ +++KL  +G +++K  L T + G++ A  G L+  V F      D     ++ + VS   VA             V   R E  + S   + +    +    + ++  +     + F    + F   H ++      D L    L  P    LP           P    N +QK  + ++  R+ + ++   P ++ G FGTGKT   A   + +++ +  + +LICT + SA ++Y+ + F  Y+         ++++ +    +  +  T+    LTE+             ++R+ +TT   A +       +      F++IF+DEAAQ+LE +A++   +    T+ + AGD  Q  P L+    +KS R     ++ RL   Y     K+ +   I   E YR+  AI+N++S   Y       Q    +    Q  P+MF   + +        D  + S+ N  EV  VVE V E+       +   +Q  I   S   AQV  +R  LR ++L  V V     + G E+ VV +S+V + +     G P     F +   ++N V++RA+  +  +GD ++L +    R+ W +FI  C E
Sbjct:  579 DW--GPISRSNYRQRMHKFLYEEEAAQQQLVAKLAMKGQVSLKTALETPALGMLFAPPGALYAKVPFHSSLLPDTDQGFLLSRAVSTALVA-----PVPAPNSTVYQVRLEARASSDHALWLLLPARCCMALGLQAQDSPILEVQFQIDPMTFRFWHQAV------DALLEEHLVVP---DLPACTLPHPWPTPPSFRGNHKQKLAVGLIAGRRPEGTKHIPPLLIYGPFGTGKTYTLAMAALEVVQ-QPHTKVLICTHTNSAADIYIREYFHDYVSSGHPEATPLRVMYADRPPRQTDPTTLQYCCLTEDRQAFRPPTGPELVHHRLVVTTTSQARE-------LQVPAGFFSHIFIDEAAQMLECEALIPLSYALSLTRVVLAGDHMQVTPRLFSVPRDKSARH---TLLHRLFLYYQQEAHKIAQQSRIIFHENYRSTAAIINFVSHHFYLAKGNPIQASGKVPRHPQHYPLMFCHVAGSPEQ-----DMSMTSWLNSAEVTQVVEKVREIYNTWPHCWGPREQRHICAVS-HGAQVSALRQELRRRNLGEVSVGSFEILPGREFRVVVLSSVHNRNSLLSPGAPT--SEFFTEPRVLNTVMTRAQSQLVAVGDAVALCSSGACRNLWRSFIRECIE 1183          
BLAST of C2H2-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9BYK8|HELZ2_HUMAN (Helicase with zinc finger domain 2 OS=Homo sapiens OX=9606 GN=HELZ2 PE=1 SV=6)

HSP 1 Score: 116.701 bits (291), Expect = 8.523e-25
Identity = 98/415 (23.61%), Postives = 186/415 (44.82%), Query Frame = 3
Query: 2010 PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNG-------IKLIKSSHKRKGAEKNTI----FSDEL------TEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVP------IICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYET----QLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKN--KSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDE 3167
            P ++ G FGTGKT   A   + ++    ++ +LICT + SA ++Y++   +Y    V+G       ++++ +       +  T+     +D+       T      +RV +TT   A +   +  P+      F++I +DEAAQ+LE +A+    + ++ T+ + AGD  Q  P L++ +  + +         +C     +++ +   +   E YR   AIV+++S+  Y            + P  +  P+MF   + +        D  + S+ N  E+  VVE V E        +   + + +      AQV  +R  LR + L +V V     + G ++ VV +STV +         L P F ++  ++N V++RA+  + V+GD ++L +       W +FI  C E
Sbjct:  539 PLLIYGPFGTGKTYTLAMASLEVIRRP-ETKVLICTHTNSAADIYIR---EYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARE---LRVPV----GFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDR-----DMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVE 937          
BLAST of C2H2-type domain-containing protein vs. TrEMBL
Match: K1RFQ6 (Putative helicase with zinc finger domain OS=Crassostrea gigas OX=29159 GN=CGI_10020563 PE=4 SV=1)

HSP 1 Score: 209.92 bits (533), Expect = 4.332e-51
Identity = 256/1065 (24.04%), Postives = 452/1065 (42.44%), Query Frame = 3
Query:  264 RCKRKECDGCSYAHNDFEFFIWNSMRNNNKFRISQLYKEFIEPYIYIPSTDNVSIRPITPVTHQQMPIYKINQVPQSKIENEIIHQEEKRKHYLCWFCLKDIASENSIPLHIESQPHKAKYDADKKRQWYFKMPCSQIALRSSDVNQNGITNQ------IDDEYLEMC----ARIKFREFLSSYTYEHIERKINPWPK---FMEFKIPFFPSNIKCYKSPIQIFPTLSISLRCHKLAIYLRDDESRPFFKLIKANQNQTVEHRSQL-----LTVCLKDNQFPCVVEFG---------------IEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKYKNYVPFNMSETTCRGVLSEEL---LGSIFKIIPNRDWI------KTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSSGLIPANDGKLFGDVKFGRH--HDQAAREIIIKCVSNCYVA-FDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDT--SEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYM-QIFQKYIPRLVNGIKLIKSSHKRKGAE--------------KNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSL--RKFSVPIICRLHNIYKLL-------KNYTITLREVYRTHPAIVNYLSQAIYY----ETQLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQ---SKILVCSPFYAQVKLIRDRLRSK--SLNRVVVEQPSNIQGCEYDVVFISTVLSS-------------DDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            +C       C +AH+  E  IW  M  ++  ++  LY    E  I   +  N +I   + VT     + K   +P           + K   Y C +C K   SE     H  S+ H    ++DK+ QW  + P   +   + ++    +  +      + D Y  MC    +  +  E+   Y +  ++R++    K   FM+  +  + S     K   +  P + ++    +L IY  + ++  F  +      +T+E  + L     L   LK+N+     +                 + F+     ++ Q + FD  T        + + V+VG+    E ++S        + +++++ ++   N       G   +EL   L S +K   + D +       T +  +NY + M  ++ +EE+++  I+S       IT+   +     + PA  G+LF  V    +   D  A ++I+  V +  +A   +    ++E  +V    ++++ R  E + +C S + V+ + +K    +   I F   R  F   H +++N      LS   +  P  +++    ++ST+     + LN +Q    +  ++ I T  SE   PF++ G FGTGKT   A+ VM +++      ILIC +S SA +LY+ +    +I +  +  K+ +   K +                   T F     E+I  +N V +T       S S+    L     F +IFVDEAAQ LE +AIM     +  T  + AGD  Q  P++Y+     +KF + ++ RL   Y          K   I LR  YRT   I+ ++S AI+Y    + +  + +    +I P+MF+   +    EIQ  D D  SF N  EV+ VVE V EL       + +     I V +P+Y QV  IR  LR K   L  V VE+ +N+QG E+  +FISTV +              + D G    +  F S+  L+N  ++RA+ FVAV+GD ++L  +    + W T+++ C    ++
Sbjct: 1107 KCGYTGGGPCQFAHSQEELEIWQWMCVHDVKKLEDLYIASKEAQITRSAQKNKAISGESVVT-----VTKRVNLPT----------QVKYSMYYCSYCGKQCNSEKQWDEHTASEKHNFNVNSDKEHQWNHRQPPWGLPGTNYELCFKHVEGRKCPYSNVPDMY-NMCQYAHSEEELDEWRERYEWRQMKREMARQEKVFSFMDELLEQYQSAEHGIKVIAEDLPDVEVTCD-QELTIY-EEKKNAVFAWIFDVQSKRTLEKVALLYNKDRLHFSLKENEIDKNTQIAQGDSFLVSHDRYRVEVHFTGNMFGSFNQWVIFDFGTLP---VLVRKLYVEVGTVGTHERVRS--------LREKLQFDHWTAENREIVRYEGANVDELEKRLTSKYKSPTSSDSVISQHSVTTELNWNNYHHKMHQLLEMEEMKRHQIISSYNLCKTITVLGSIQEQMLVFPAQKGELFAKVPLAEYLTEDTDAGKLILTSVRSVLLAPQSQSGSNVYEGVIVGKDNFDFDGRGKEYLYLCLSSKCVQGLKLKPGMTLNVEIQFQMDRRWFCMMHYAVDN------LSSTDVVFPDLSKIKPFHEKSTLSIN-SSVLNADQ----LTAVQHIVTERSEYNPPFVIYGPFGTGKTETIAQAVMVLIKERKDFKILICAQSNSAADLYITKHLDPFIEKTKSNAKIRRVYFKDRRVNTVQDKVKKYCMLTPDKTAFEFPTHEDITKHNIVIVTL------STSLLLAELGLQDYFTHIFVDEAAQTLEAEAIMPLTLASKNTCVVLAGDHQQISPKVYSPEACEQKFDMSLLERLFQYYDSFSHKIDPAKPLNILLRINYRTKMEILRFIS-AIFYGGPDKLESKANLPSVLEITPLMFY---AVQGMEIQ--DSDSISFYNMSEVQEVVERVYELYNRWPTEWGERNPQTIGVVTPYYDQVLFIRKSLRKKHPELKNVTVERVNNVQGKEFRALFISTVRTRSLIDNNYNPDKECEGDGG----NFGFLSDPKLLNTALTRAQSFVAVVGDPVALCAIGECLNVWKTYLKHCQNMKSI 2115          
BLAST of C2H2-type domain-containing protein vs. TrEMBL
Match: V3ZS15 (C3H1-type domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_106967 PE=4 SV=1)

HSP 1 Score: 207.223 bits (526), Expect = 6.336e-51
Identity = 246/963 (25.55%), Postives = 421/963 (43.72%), Query Frame = 3
Query:  546 CWFCLKDIASENSIPLHIESQPHKAKYDADKKRQWYFKMPCSQIALRSSDVNQN---------GIT---NQIDDEYLEMCARIKFRE-----------FLSSYTYEHIERKI---NPWP---KFMEFKIPFFPSNIKCY----KSPIQIFPTLSISLRCHKLAIYLRDDESRPFFKL----IKANQNQTVEHRSQLLTVCLKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKYK----NYVPFNMSET----TCRGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSSGLIP----ANDGKLFGDVKFGRH--HDQAAREIIIKCVSNCYVAFDKFKIFLFECELVD-FFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNN---------LNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQ-IFQKYIPRLVNGIKLIKSSHKRKGAE-------KNTIFSDEL------TEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISL--MKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLK---NKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD----DDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFAN 3176
            C FC      +  +  H  S  HK +  +D+ + W F+ P   ++     + Q          G+       ++E  E   R KFR              +S+T + +ER +   NP     + ++F      +++K      +S      T++  +  H +   L DD ++ +F +    +   + Q  ++      +C   +   C +   +  + I+  T+RQ I FD      E    + I+V+  S   L+ L S       +IT+  ++     N  PF +S      + + +L++  L    K       I  T+   NY  WM +M+ LEE+ Q   +S    +  + + N  +   G +     AN+G+LF  +K       D  +  +I++     Y+A  K      E  L    +    E +    + +   K  VE + +   E V   + F  +RL     HA+++ +P  D            T  P  ED  +I + P            LN +QK+  + +   ID      P ++ G FGTGKT   A+    +L+    S ILICT S SAG+LY++  F  +       +K ++  +K +  +       K ++F          T E    +RV ITT+ N A  +S    I +    F++IF+DEAAQ LE + ++        T+ + AGD  Q  PE+Y    R+  F + ++ RLH  Y       I L E YR+H AIV++ S+ ++YE +LIS    K   ++ P+ F+ +      E+Q   ++   F N  EV  VVE V++L +   ++    + S I + +P+  QVK IR+ LR + L  + VE+  NIQG ++ VV +STV + +    D S   ++   F SN  L+N  ++RA+  V V+GD +SL  V   R  W  F+E+C++ ++
Sbjct:    1 CTFCDIKFNKKEELETHCRSDLHKKRLTSDEGQDWKFRPPPRGLSSEEYSLCQRYSALFRCSFGVKCTEAHSEEELNEWKERFKFRREQLQKAREKLLHGNSFTEKLMERLMLSENPRAILVQSLDFVKLHINADLKVTMPNKRSTFAWTFTVTSKMSLHNVC--LLDDVNKSYFYISSISVGPKKTQKYQNLENHYGMCKNSSPLICYLTQVVFKTDIF-GTFRQSIIFDF---GFETVLMREIQVE--SETDLDKLASDI-----IITEANRWTKDKVNITPFQLSSEYLSESDKNLLAKYSLPQAEKFSRPESAIMQTLNKKNYREWMHEMLYLEEMAQFSSISGFNIKTALQLVNRFLLMPGALSIAKYANNGELFAKMKLEDDLCEDSISGRLILQNAQFAYIALCKSNK---EKSLPKKAYEVYIEDKGKNFIFLRLPKVCVEELKLSCDEEVTVLVQFQLNRLPKVEMHAAVDKLPSID------------TVFPTLEDYKSIPWSPSRQCDSELNGCKLNAKQKEAVLAI--TIDPETKLPPLLIVGPFGTGKTYTLAQAAKQVLKQLDGSRILICTHSNSAGDLYIKDFFHAWFEEGNEEMKPLRIIYKNRWVQTVSETVLKYSLFDSHTSTFKYPTLEDLEKHRVIITTL-NTARYISD-LNISKGKWFFSHIFIDEAAQALECETLIPLSMSCESTRLVLAGDHMQLSPEVYADFCRQQYFQMSLLERLHEYYPHDHPCKIMLCENYRSHSAIVDFTSE-LFYENKLISSGKQKAHSKLYPLTFYAAK---GEEVQ--HQNSTGFYNAAEVFEVVERVVDLQRKWLDEWGPMNDSSISIVTPYADQVKFIRNELRRQKLYHISVERVHNIQGKQFRVVILSTVRTQNTCRSDTSEEDLMDYGFLSNLKLLNTAITRAQSLVMVVGDPVSLCLVGKCRKVWEYFLEICNQHSS 925          
BLAST of C2H2-type domain-containing protein vs. TrEMBL
Match: W8BQS1 (Putative helicase with zinc finger domain (Fragment) OS=Ceratitis capitata OX=7213 GN=HELZ PE=2 SV=1)

HSP 1 Score: 204.527 bits (519), Expect = 1.554e-49
Identity = 208/781 (26.63%), Postives = 361/781 (46.22%), Query Frame = 3
Query: 1074 IEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDV---GSNEHLENLK-----SSWERYKDVITQEVKYKNYVPFNMSETTCRGVLS--EELL-------GSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITI-KNHLMTSSGLIPAN-----DGKLFGDVKFGR--HHDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNN--------LNEEQKKLPILVLRKIDTS-EIALP-FILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIK----LIKSSHKRKGAEKNTIFSD-----------ELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNK--SLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK-PTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQ---SKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDD---------DSGIPILHPT-------------FHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            IEF      T+RQ + FDL T   E    + + VDV   G  E +E +K     SS  R+    T  VK++  +  ++        L   +E+L          F +      ++  +  HNY + + +++ +EE+ +   +++      +T+  N+++T +G+  +       G+LF  ++ G+    D +A  +I+   S+ Y++       L E +    +    E +    + +  S + VE +++K    +E  I F  +RL +   H +++ +            + F    P  E E  I + PK          LN +Q++     +  I T+  I LP  +L G FGTGKT   A+ +  +L  + ++ ILICT S SA +LY++ +    P +  G++    L    HKR  A  N++                T E    +R+ + T+  + +  ++  P       F +IF+DEAAQ +E +AIM     N  T+ + AGD  Q  PEL++     RK  + ++ RL++ Y       I L E YR H AI+ + S+ ++YE +LI+  K P ++   P+ FF   +T   ++Q  DK+  +F N  EV  VVE V EL +    ++ +   + I + +P+  QV  IR  LR + +  + VE+  N+QG ++  VF+STV +             +G   +HP+             F SN  L+N  ++RA+  VAV+GD ++L ++   R  W  FIE+CDE  +L
Sbjct:  534 IEFHTDIYGTFRQTVCFDLGT---EPMLVQQLCVDVVPVGDAERIEEIKRDIINSSVTRWDVSNTNLVKFETTIGTHLKTEAYLNDLKHEKEMLERYPCPRAQTFTLT-QSTIVEKRLTQHNYRSRIHELLYVEEIARYEQIARYNVRTKLTVASNYILTPAGMATSTAKFSLTGELFALMRLGKDISEDTSAGRLILSNCSSVYISAPDDMHPLKERKR-SVYEATIEDKGKNVIYLKLSAKCVEGMSLKADTEIEVDIQFQLNRLPYCEWHNAVDKI------------TDFKIIFPATETEPNIPWTPKKQWSDACEPKLNAKQRE----AVNAITTTLSIKLPPILLIGPFGTGKTYTLAQAIKQLL-TQPEAKILICTHSNSAADLYIKEYLH--PWIEQGVEEATPLRVYYHKRWVATVNSVVQKYCITDPAGNFRRPTVEDIKKHRIVVVTLSISMELANLGLPK----GYFTHIFLDEAAQAMECEAIMPLALANDSTRIVLAGDHMQMSPELFSAFAKERKLHISLLERLYDHYPSNFPCKILLCENYRAHEAIIKFTSE-LFYEQKLIASGKQPRHERFYPLTFF---TTRGEDVQ--DKNSTAFYNNAEVYEVVERVSELRRKWPVAWGKVNDASIGIMTPYADQVFRIRSELRKRRMGGISVERVLNVQGKQFRAVFLSTVRTRATCLPQMINAMMTGQGGMHPSGMGGLPAEDADYGFLSNSKLLNTAITRAQSLVAVVGDPVALCSIGRCRKVWERFIEICDENKSL 1280          
BLAST of C2H2-type domain-containing protein vs. TrEMBL
Match: R7TV95 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_227646 PE=4 SV=1)

HSP 1 Score: 203.756 bits (517), Expect = 3.421e-49
Identity = 168/655 (25.65%), Postives = 309/655 (47.18%), Query Frame = 3
Query: 1353 RDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSSGLIPANDGKLFGDVKFGRH--HDQAAREIIIKCVSNCYVAFDKFKI-FLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNL------NEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYM--QIFQK---------YIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNY-------TITLREVYRTHPAIVNYLSQAIYYETQLI---SLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSK---ILVCSPFYAQVKLIRDRL-RSKSLNRVVVEQPSNIQGCEYDVVFISTVLSS-------DDDSGIPILHP---TFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            +D + T +  HNY + M  ++ LEE  +  +++    +  + + N +   S ++ A  G LF  V    H   D  A ++I+  V +  +     +   ++E  +++   +  E +  + + +  S   V+ ++++N + ++  I F   RL F   H +L+ +   D L  N   +P             +V KPK++L      N+EQ  +   ++RK+       P  + G FGTGKT   A++ MA++E + +S +LICT S S+ +LY+   + +K         Y  R V  +  I  ++  +  E++        E      ++ +TT+  A+  + +          F +I +DEAAQ LE +AI      N +T  + AGD  Q +P++Y+   ++  F   ++ RL+ +Y  ++ +       ++ LRE YRT   ++ ++S+  Y   +++   S ++    + PM F+     +S   +  D +  SF NE E++ +V+ V  L K     + + +   I V SP+ AQV+ IR  L R + L  V VE+  N+QG E+  VFISTV SS       + D      H     F S+  L+N  ++R K FV V+G+ + L  V   +  W +F++ C +  ++
Sbjct: 1026 QDSVGTAINQHNYVHKMHSLLRLEEFTRARLIASYNLQTRLELINTIFEGS-MVSALPGHLFAKVPLTTHLSADSNAGQLILDSVQSALLKPSSIRSDVVYEAMVLNQQNFNLEGKGRDYIYLSLSACCVKELSLENGDHLDVDIQFQMDRLPFASMHETLDALHSTDILFPNVAAAP-------------LVPKPKSHLRLGVHLNKEQSNILNHIIRKVSF----FPMSVCGPFGTGKTESLAQSAMALIEEQPQSRVLICTHSNSSADLYILRHLSKKSSIKLCRIVYTGRWVRTVPPIVRNYCFESPERDRFVEPSRAE--VEQCQIVVTTLSTASSVVKLGL-----RGHFTHILIDEAAQALECEAIKPLVLANARTCIVLAGDPMQMQPKVYSAEAQRQNFQASLLERLYRLYGDMEKHCRDSVPPSLLLRENYRTDSRLLRFISEVFYGHAEMLIARSELEVAQTVPPMAFY-----VSKGEETIDAEGTSFYNEAEIQEMVDQVAALYKYWPHEWGERRAELIGVLSPYQAQVQRIRFALRRHRELKAVNVERVDNVQGKEFRAVFISTVRSSNLSLPSVEQDVSECSGHAGQLGFLSDSRLLNTAITRTKSFVGVVGNPVVLCGVGSCKTLWRSFLKTCRQLHSI 1650          
BLAST of C2H2-type domain-containing protein vs. TrEMBL
Match: A0A4Y2CFZ0 (Putative helicase with zinc finger domain OS=Araneus ventricosus OX=182803 GN=helz PE=4 SV=1)

HSP 1 Score: 202.986 bits (515), Expect = 3.792e-49
Identity = 205/736 (27.85%), Postives = 332/736 (45.11%), Query Frame = 3
Query: 1098 STYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLK-------SSWERYKDVITQEVKYKNYVPFNMSETTCRGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPIT-IKNHLMTSSGLIPA---NDGKLFGDVKFGR---HHDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQ----------IFQKYIPRLVNGIKLIKSSHKR---------KGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYN--KSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTY-QIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS---------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMC 3161
             T+RQ + FD      E    K + VDV S   +E L+       S  ER+       V ++N  P+ + E   + +L+     S  K    ++ ++T +  +NYC    +++ +EE+ Q  +LS+   +  +T +  +L+T +  + A     G+LF ++          Q+ R ++  C S   +A    K      E    +    E +    + I  SKQ  E ++ K  +   A + F  +RL     H ++      D+L    L  P  T  P   + + I       LN +QK+  + +   + T     P ++ G FGTGKT   A+ V  IL  E  S IL+CT S SA ++Y++           F+    R+    + + + H            G E+  +     T +   + +V +TT+  A   + +    LEK   F +I +DEAAQ +E +AIM     N  T+ + AGD  Q  PE+Y+     R     ++ RL+++Y       I L E YR+H AI+ Y S+  Y      S  +P + +  P+ FF   +    +IQ  D +  +F N  EV  +VE V+EL KN    +   D++ + V +P+Y QV  IR  LR K L+ V VE+  N+QG ++ V+F+S V +         SD D G       F SN  L+N  ++RA+  VAV+GD +SL +V   R  W  FI  C
Sbjct:  216 GTFRQDLVFDF---GFEPVLVKKLCVDVVSISDMEKLQQAREEVVSYTERWSSADVTVVPFENR-PYPIGEQE-KNLLACYPPPSGQKFTMTQNAMETALTENNYCARQHELLNIEEMSQYELLSRYNVQATLTLVDRYLLTPNSAVTAKYAQGGELFANMTLTSVLSEDSQSGRLVLTNC-STVLIAPLSSK----GEEHRKVYEAVIEDKGKTVIYIRLSKQCCEELSFKTDQEFVAEVQFQLNRLPLCEMHFAV------DRLHPPSLVFPDVTVRPQLWN-NHITLSSDVKLNPKQKEAVLAITTPLSTR--LPPVLIIGPFGTGKTYTLAQAVKIILSQE-NSRILVCTHSNSAADIYIREYLHPYVAEGKFEATPLRIYYRHRWVATVHPTVQQYCLINYNGNERKFVMP---TIKDVKSRKVIVTTLSTARYLVQLG---LEK-GFFTHILIDEAAQAMECEAIMPLSLANENTRIVLAGDHMQLSPEVYSVFAQQRNLHTSLLERLYDLYPEDFACKILLCENYRSHEAIIQYTSELFYDNHLKASAQQPRHKKYYPLTFF---TARGEDIQ--DCNSTAFHNYAEVNEIVERVIELKKNWPSCWGEQDETSVGVVTPYYDQVVRIRAELRKKKLHGVSVERVLNVQGKQFRVIFLSAVRTRQTCGSKAESDLDHG-------FLSNARLLNTAITRAQSLVAVVGDPVSLCSVGKCRKLWEKFIYTC 912          
BLAST of C2H2-type domain-containing protein vs. Ensembl Cavefish
Match: helz (helicase with zinc finger [Source:NCBI gene;Acc:103032941])

HSP 1 Score: 174.096 bits (440), Expect = 1.880e-43
Identity = 208/845 (24.62%), Postives = 364/845 (43.08%), Query Frame = 3
Query:  924 HKLAIYLRDDESRPFFKLIKANQNQTVEHRSQ--LLTVC--------LKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSS----------WERYKDVITQEVKYKNY-----------VPFNMSETTCRGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGRHHDQ---AAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEY--ESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-------QKKLPILVLRKIDTSEIAL---PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIF-QKYIP---------RLVNGIKLIKSSH---KRKGAEKNTIFSDEL-TEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK--PTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS----------------------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            H++A+    D +RP F ++  +   T     Q    + C        +++    C+    + F+     T+RQ + FD  +   E    + + VD  S E LE+L  +          W+     I + V  +N            +P +  +   + VL + L          RD         NY   + D++ +EE+ Q   +SK   +  + + +  M    S G   A +G+LF   K      +   A R ++ K  S   +   + ++            YE   E ++ + + +   K+  + + +     ++  + F  +RL     H +L      D+L  N +  P     P      TI + P    +E+       ++K  IL +    T+ +++   P ++ G +GTGKT   A+ V  IL+ +  S +LICT S SA +LY++ +   Y+          R+    + +K+ H   ++        F+ ++ T +    +RV + T+     S S +   L+ +  +F +I +DEAAQ +E + IM     +  T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+ ++YE +L++  K  P     P+ FF +         V +K+  ++ N  EV  +VE V E+ K    ++   D+  I V SP+  QV  IR  LR K ++ V VE+  N+QG ++ V+F+STV +                       D D G       F SN  L+N  ++RA+  VAV+GD ++L +V   R  W TFI +C E  +L
Sbjct:  248 HRIALLY--DANRPHFSIMAVSAGDTSSQVQQEGCESGCQEWSGAGLVQNGMDHCLYTVEVAFNTEIFGTFRQTVVFDFGS---EPVLMQRVMVDAASIEDLEHLMQARQQLLMTAKRWDSSCKTIVEFVPGENMELERSLLSRYQIPLSADQLFTQSVLDKSL---------TRD---------NYQARLHDLLYIEEIAQYKEVSKFNIKVNLQLVSSFMLTGISGGAKYAQNGQLFARFKLTETLSEDTLAGRLVMTKVNSVLLLPASRERVGQGHPTSSKERVYEALIEEKTKDYIFLRICKECCDELGLAPDRELQVELQFQLNRLPLCEMHYAL------DRLRDNSILFPDTGLTP------TIPWSPNRQWDEQLDPRLNAKQKEAILAI----TTPLSINLPPVLIIGPYGTGKTFTLAQAVKHILK-QPDSRVLICTHSNSAADLYIKDYLHPYVEAGNPHARPLRVYFRNRWVKTVHPVVQQYCLISGAYFTFQMPTRQDIERHRVVVVTL-----STSQYLCQLDLEPGLFTHILLDEAAQAMECETIMPLALASKSTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPSEYPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPPHKDFYPLTFFTARGE-----DVQEKNSTAYYNNAEVFEIVERVEEMRKKWPVAWGKLDEGSIGVVSPYADQVFRIRAELRKKRMHEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAIKRKEQLVEDSTEDLDYG-------FLSNYKLLNTAITRAQSLVAVVGDPIALCSVGRCRKFWETFISICHENGSL 1034          
BLAST of C2H2-type domain-containing protein vs. Ensembl Cavefish
Match: helz (helicase with zinc finger [Source:NCBI gene;Acc:103032941])

HSP 1 Score: 172.555 bits (436), Expect = 4.680e-43
Identity = 208/845 (24.62%), Postives = 364/845 (43.08%), Query Frame = 3
Query:  924 HKLAIYLRDDESRPFFKLIKANQNQTVEHRSQ--LLTVC--------LKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSS----------WERYKDVITQEVKYKNY-----------VPFNMSETTCRGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLM---TSSGLIPANDGKLFGDVKFGRHHDQ---AAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEY--ESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEE-------QKKLPILVLRKIDTSEIAL---PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIF-QKYIP---------RLVNGIKLIKSSH---KRKGAEKNTIFSDEL-TEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMK--PTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS----------------------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            H++A+    D +RP F ++  +   T     Q    + C        +++    C+    + F+     T+RQ + FD  +   E    + + VD  S E LE+L  +          W+     I + V  +N            +P +  +   + VL + L          RD         NY   + D++ +EE+ Q   +SK   +  + + +  M    S G   A +G+LF   K      +   A R ++ K  S   +   + ++            YE   E ++ + + +   K+  + + +     ++  + F  +RL     H +L      D+L  N +  P     P      TI + P    +E+       ++K  IL +    T+ +++   P ++ G +GTGKT   A+ V  IL+ +  S +LICT S SA +LY++ +   Y+          R+    + +K+ H   ++        F+ ++ T +    +RV + T+     S S +   L+ +  +F +I +DEAAQ +E + IM     +  T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+ ++YE +L++  K  P     P+ FF +         V +K+  ++ N  EV  +VE V E+ K    ++   D+  I V SP+  QV  IR  LR K ++ V VE+  N+QG ++ V+F+STV +                       D D G       F SN  L+N  ++RA+  VAV+GD ++L +V   R  W TFI +C E  +L
Sbjct:  286 HRIALLY--DANRPHFSIMAVSAGDTSSQVQQEGCESGCQEWSGAGLVQNGMDHCLYTVEVAFNTEIFGTFRQTVVFDFGS---EPVLMQRVMVDAASIEDLEHLMQARQQLLMTAKRWDSSCKTIVEFVPGENMELERSLLSRYQIPLSADQLFTQSVLDKSL---------TRD---------NYQARLHDLLYIEEIAQYKEVSKFNIKVNLQLVSSFMLTGISGGAKYAQNGQLFARFKLTETLSEDTLAGRLVMTKVNSVLLLPASRERVGQGHPTSSKERVYEALIEEKTKDYIFLRICKECCDELGLAPDRELQVELQFQLNRLPLCEMHYAL------DRLRDNSILFPDTGLTP------TIPWSPNRQWDEQLDPRLNAKQKEAILAI----TTPLSINLPPVLIIGPYGTGKTFTLAQAVKHILK-QPDSRVLICTHSNSAADLYIKDYLHPYVEAGNPHARPLRVYFRNRWVKTVHPVVQQYCLISGAYFTFQMPTRQDIERHRVVVVTL-----STSQYLCQLDLEPGLFTHILLDEAAQAMECETIMPLALASKSTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPSEYPCRILLCENYRSHEAIINYTSE-LFYEGKLMASGKQPPHKDFYPLTFFTARGE-----DVQEKNSTAYYNNAEVFEIVERVEEMRKKWPVAWGKLDEGSIGVVSPYADQVFRIRAELRKKRMHEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAIKRKEQLVEDSTEDLDYG-------FLSNYKLLNTAITRAQSLVAVVGDPIALCSVGRCRKFWETFISICHENGSL 1072          
BLAST of C2H2-type domain-containing protein vs. Ensembl Cavefish
Match: helz2 (helicase with zinc finger domain 2-like [Source:NCBI gene;Acc:103025927])

HSP 1 Score: 144.436 bits (363), Expect = 2.874e-34
Identity = 160/633 (25.28%), Postives = 276/633 (43.60%), Query Frame = 3
Query: 1371 TVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIK---NHLMTSSGLIPANDGKLFGDVKFGRH--HDQAAREIIIKCVSNCYVAFDKFKIFL---FECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKL--SYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQI-FQKYIPRLVNGIKLIKSSHKR---KGAEKNTIFSDELTEEIFT----------NNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYN-KSLRKFSVPIICRLHNIYK-----LLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKN---KSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSL--TTVNPTRDQWSTFIEMC 3161
            ++ + NY   M   +  EE+ +  ++ +L   G +++K   N    +   IP   G+LFG V        D     ++ + V +  V     K  L   +E  ++     E E      V +  S +    +N+ N   VE  I F   RL F   H +++ +P   ++        +P   +   GE            LNE+Q+     +L   D      P ++ G FGTGKT   A+  +A L  + ++ ILICT + S+ +LY++  F   +    +  + ++   K    K     T+    L+++ +T            R+ ITT      +L+ FF  L+   + F++IF+DEA+Q+LE +A+M       KT+ + AGD  Q  P L++ +  ++    I+ RL + Y+       KN  I   E YR+   IV+++S   Y   + +   K      P         +  E  +  + L  F N  +++ VVE V ++L     K    D + I V S   +QV  IR RLR   L  V VE   N+QG ++ V+ I+TV + D  +     +  F ++  ++N  ++RA+  V V+GD  +L  +        W ++IE C
Sbjct:  593 SINYKNYKEKMHCFLYREEITEDQLVRRLNLRGKMSLKKIINQWYETKFAIP---GELFGSVSIAHSLTPDTPEGYMLKRHVQSALVGLPSPKAGLQRVYEAIVLKDMVGETE------VHLSLSGKCCTELNLNNETTVEMEIQFQLDRLGFCDMHKAVDILPDLSRVLPDLTDSNAPVPIKSSPGE------------LNEKQQAAMDFILGTSDQEGNTAPLLIYGPFGTGKTFTLAKITLA-LAKKPQNKILICTHTNSSADLYVKDHFHTSVTTADDAARPLRIKAKEIPLKTTHPYTLQYCHLSKDGYTFDFPDTATLDAKRIIITTT-----TLARFFHDLQLPPNYFSHIFIDEASQMLECEALMALGLAGEKTQVVLAGDHMQMGPRLFSVEEDKRSDHTILNRLFHYYQSENTTTAKNRRIIFNENYRSTVEIVDFVSTHFYVGKKDVIKAKGNVSPHPDQCALQFVHVRGECHLDSRTLTWF-NPVQIQSVVEVVQDVLNKWPEKWQERDPTSICVVSQG-SQVTEIRTRLRYAKLGLVTVENAENVQGKQFRVIIINTVHTKDSLNVSEETYLEFFNDMRVLNTAMTRAQSQVIVVGDAAALCCSYFGKCWRLWRSYIEHC 1196          
BLAST of C2H2-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000014945.2 (Mov10 like RISC complex RNA helicase 1 [Source:NCBI gene;Acc:103044404])

HSP 1 Score: 86.6557 bits (213), Expect = 1.046e-16
Identity = 105/430 (24.42%), Postives = 184/430 (42.79%), Query Frame = 3
Query: 1935 NNLNEEQKKLPILVLRKIDTSEI-ALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQK--YIP-----------RLVNGIKLIKSSHKRKGAE-KNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKT-KFIFAGDIFQTRPELYNKSLRKF--SVPIICRL--HNIYKLLKN-----YTITLREVYRTHPAIVNYLSQAIYYETQLISLMK------------PTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHP-TFHSNRNLINLVVSRAKHFVAVIGDKMSL 3110
            +NLN  Q++     +++I   E    P++L G  GTGKT+   E ++ +      S IL+CT S SA +L      +  ++P           RL   I  +   + R G + +N  F           +R+ ++T  +A     MF+ I  ++  F ++F+DEA Q  E +A +     + +T + + AGD  Q  P + +K    F   V ++ RL  + +Y   +N         L   YR+H  ++   S+  Y     +   +            PT +  P++F     +     ++ +    S+ N  E   V+    +L K        + I + SP+  QV+ IR  L    L  + V      QG E+ V+ +STV S++D SG  + +   F SN    N+ ++R+K  +  IG+   L
Sbjct:  738 SNLNPAQRQ----AVKRILGGECRPTPYVLFGPPGTGKTITLVEAILQVYHRVTGSRILVCTPSNSAADLICIRLHESGFLPAASLARVNATCRLEESIPEVLHQYSRAGEDIRNACF-----------HRIVVSTCSSAG----MFYQIGLRIGHFTHVFLDEAGQATEPEAQIPLGLLSERTGQIVLAGDPKQLGPVVKSKLAEAFGLGVSLLERLMANPLYSCSENGYNPLLVTKLVYNYRSHEVLLALPSRLFYGGELCVRSQRSVVDSLCHWGRLPT-KGFPLIFHGVRGS-----EMREGSNPSWFNPVEAVQVMLYCCQLAKRLYNPIPATDIGIISPYRKQVEKIRVLLHKVGLGDIKVGSVEEFQGQEFLVIILSTVRSNEDLSGSDLQNVLGFLSNPKRFNVAITRSKALLITIGNPHVL 1142          
BLAST of C2H2-type domain-containing protein vs. Ensembl Cavefish
Match: mov10a (putative helicase mov-10-B.1 [Source:NCBI gene;Acc:103034927])

HSP 1 Score: 84.3445 bits (207), Expect = 4.267e-16
Identity = 103/441 (23.36%), Postives = 190/441 (43.08%), Query Frame = 3
Query: 2010 PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYI--------------PRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAI--MVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRL---HNIYKLLKN--------YTITLREVYRTHPAIVNYLSQAIYYETQLI----SLMKPTY--------QIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAV--LELLKNKSF--SFDQSKILVCSPFYAQVKLIRDRLRS----KSLNRVVVEQPSNIQGCEYDVVFISTVLSS------DDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDE 3167
            P+++ G  GTGKT+   E +  +  +   + +L C  S SA +L  +   +Y+              PR +   KL+K S+  +G +   + S    +E      V + T+  A   +S   P+      F ++F+DEA Q +E + +  +       K + + AGD  Q  P L +   ++    + ++ RL   +++Y+   +        +   L   YR+HPAI+  +   ++Y+ +L      + +  +        Q  P++F         E      +  SF N  E+++++  +  L+L + K        + I + +P+  QV+ IR  L++    K  N + V      QG E  V+ +S V SS      D D  I      F +N    N+ ++RAK  + V+G+ + L   NPT   W  FI+ C++
Sbjct:  535 PYLIFGPPGTGKTVTLVEAIKQVNRSGTVAHVLACAPSNSACDLLCERLLRYVDGHHLYRLCASSRDPRTMPQ-KLLKHSNWDEGQDSFILPS----KETLMGYSVIVVTLITAGRLVSGGVPV----GHFTHVFIDEAGQAVEPECVVGIAGLLHPEKGQVVLAGDPQQLGPILRSPLAQQHGLGLSLLERLMTQNSLYQKTHDGSQAYNSCFVTKLLRNYRSHPAILE-IPNELFYDNELQVFADQMEREAFCHWEHLPKQGFPVIFHGVMGKDEREA-----NSPSFFNVSEIEVLISYLQKLKLTQGKKGLPKLKPADIGIIAPYRKQVEKIRKALQTVKELKQWNDIKVGSVEEFQGQEKRVIMVSAVRSSISYVKMDQDFNI-----GFLTNEKRFNVAMTRAKALLIVVGNPVILNK-NPT---WQRFIQYCEQ 951          
BLAST of C2H2-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006694.1 (pep scaffold:Pmarinus_7.0:GL476853:158045:174859:1 gene:ENSPMAG00000006033.1 transcript:ENSPMAT00000006694.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 135.191 bits (339), Expect = 2.473e-32
Identity = 158/628 (25.16%), Postives = 274/628 (43.63%), Query Frame = 3
Query: 1386 NYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSSGLI-PANDGKLFGDVKFGRHHDQAARE--IIIKCVSNCYVAFDKFKIF--LFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQ---------IFQKYIP-RLV---NGIKLIKSSHKRKGA-EKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYN--KSLRKFSV-PIICRLHNIYKLLKNYT-----ITLREVYRTHPAIVNYLSQAIY---YETQLISLMK----PTY-QIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKS---FSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS-SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFI 3152
            NY   +   +  EE  Q  +LS+L  +  + IK  +   +G I  A+ G LF +V         + E  ++ + V    VA    +    ++E  L        +  S++ + +   +     + + +       + F    L F  RHA+++ +          L  P  T          I+       N++QKK+ +  + +    +   PF++ G FGTGKT    +  + IL AE  + +LICT + SA +LY+Q          F++  P R+V     +  +    +R    + N  F    + EI   +RV I T         +  P       F++I +DEAAQ LE DA++     +  T+ + AGD  Q  P+LY+     ++F +  ++ RL + Y+   + T     I L + YR+ P IVN++S+  Y   ++     +      P +  + P+ F   S         FD+   ++ N  E   V E V  +L+         +QS+I V S + +QVKLIR  LR K +  V V+   +IQG E+ V+ +STV + S   S +   +  F ++   +N  ++RA+  V  +GD M+L +V      W +F+
Sbjct:  586 NYQQSLHTALYREEAAQETVLSRLNLQTEVLIKKMVHMPTGEIYIASTGMLFAEVPIPPQMGPDSEEGMLLRRSVDVALVALPGSEDGSPVYEVSL------SKDLCSVDCLRLLLPESVCRALALDDGTSRPLDVQFQLDHLTFCIRHAAVDQMDAR-------LILPDITNCALPTTRPGILPATLKG-NDKQKKVIMFAVGERTCDKPTPPFLMYGPFGTGKTYTLFQATVQIL-AEPNARVLICTEANSAADLYIQEYLHEYVTSGFKEATPLRIVYKWRNMNTVSEVVRRYCCLDPNGPFFAVPSLEIVKAHRVVIATYAQCRTLWQLELP----RGHFSHILLDEAAQALEADALIPLALADSSTRVLLAGDHKQITPKLYSMPNDDKQFVIRTLLQRLFHHYQRQNHNTAQCSRIILTDNYRSRPEIVNFVSKHFYLGNHDKDFKGIKARADVPRHPDLYPLTFSHVSGKCD-----FDEVTRTWYNTTEALEVAERVANILQTWPEIHGRLEQSQICVISYYSSQVKLIRYVLRRKHMGSVNVDTLQSIQGKEFTVIVLSTVRTRSSRQSMVTDGNLGFLADACALNTAMTRARALVLAVGDAMALCSVGGCSRVWQSFL 1189          
BLAST of C2H2-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008661.1 (pep scaffold:Pmarinus_7.0:GL478401:184160:191851:-1 gene:ENSPMAG00000007841.1 transcript:ENSPMAT00000008661.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.6254 bits (161), Expect = 1.420e-11
Identity = 89/361 (24.65%), Postives = 149/361 (41.27%), Query Frame = 3
Query: 2142 YMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYK--TKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYET-QLISLMKPTY----QIVPMMFFDSSSTLSNEIQVFDKDLC---------SFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDS-------GIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIE 3155
            Y Q  +KY  R    I+++K     +  +   +  D    E+  ++ V ITT   AA  +     +L+ L       VDE A   E + ++     +YK   + +  GD  Q RP + N++  K  +       ++++      I L   YR HP I  + ++  Y ET + +   K  +     I+      S  TL   +   +  L          S  N+ EV+ VV  V EL+K  S +  +  I + +P+ AQ   I+  L  + + +V     +  QG E+  V +STV S   D        G  I    F  + N +N+ ++RAK  + +IG++  L       D W   IE
Sbjct:   78 YAQQIRKYDER----IRILKKFRSMQSKKYKKLIKDAKVIELKKSD-VVITTCSTAATVI-----LLKNLDP-RVCLVDECAMCTEPECLI--PLTSYKDIAQVVLLGDHKQLRPFVLNRTAAKLGME-----KSMFERYAKRAIMLDTQYRMHPDICEFPAKQFYSETNKTLKTAKEVFGRPNSILGYAHKPSCPTLFGHVVGKEVTLVVSTEEGSENSKANKAEVEQVVRLVSELIKKGSIA--EKDIAILTPYNAQANEIQKALEKEHIKKVTATTITKSQGSEWRYVLLSTVRSCSLDEFKANPSRGWQISRLGFIIDENQVNVALTRAKEGLCIIGNQDLLM----CSDLWKELIE 414          
BLAST of C2H2-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008666.1 (pep scaffold:Pmarinus_7.0:GL478401:184246:194592:-1 gene:ENSPMAG00000007841.1 transcript:ENSPMAT00000008666.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.2402 bits (160), Expect = 2.416e-11
Identity = 73/287 (25.44%), Postives = 120/287 (41.81%), Query Frame = 3
Query: 2370 FVDEAAQVLEVDAIMVYQFGNYK--TKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYET-QLISLMKPTY----QIVPMMFFDSSSTLSNEIQVFDKDLC-----------SFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDS-------GIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIE 3155
             VDE A   E + ++     +YK   + +  GD  Q RP + N++  K  +       ++++      I L   YR HP I  + ++  Y ET + +   K  +     I+      S  TL     V  K++            S  N+ EV+ VV  V EL+K  S +  +  I + +P+ AQ   I+  L  + + +V     +  QG E+  V +STV S   D        G  I    F  + N +N+ ++RAK  + +IG++  L       D W   IE
Sbjct:  203 LVDECAMCTEPECLI--PLTSYKDIAQVVLLGDHKQLRPFVLNRTAAKLGME-----KSMFERYAKRAIMLDTQYRMHPDICEFPAKQFYSETNKTLKTAKEVFGRPNSILGYAHKPSCPTLFG--HVVGKEVTLVVSTEEGSENSKANKAEVEQVVRLVSELIKKGSIA--EKDIAILTPYNAQANEIQKALEKEHIKKVTATTITKSQGSEWRYVLLSTVRSCSLDEFKANPSRGWQISRLGFIIDENQVNVALTRAKEGLCIIGNQDLLM----CSDLWKELIE 474          
BLAST of C2H2-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000979.1 (pep scaffold:Pmarinus_7.0:GL478231:754:10442:1 gene:ENSPMAG00000000889.1 transcript:ENSPMAT00000000979.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.9062 bits (115), Expect = 6.281e-6
Identity = 82/337 (24.33%), Postives = 133/337 (39.47%), Query Frame = 3
Query: 2157 QKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYT--ITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQIVPM---MFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFI 3152
            QKY   +   I+  +S ++  GAE+     +E    I    RV   T   AA     +   L+K+     + V+EAA+VLE   +     G      I  GD  Q RP   + ++ + +      +    +L++N    + L+  +R  P I   L   IY E +    +     I  M   +FF   S L  E+     D  S  N  E + VV     L+      +  ++I V + +  Q+  +R  +       V V      QG E D+V +S V S+ +        P F  N N   + +SRAK  + V+G+   L    P    W+  +
Sbjct:    5 QKYQAEIRWQIQTHESEYQ-TGAERLADVREEEELAILRQARVIGMTTTGAAK----YRHTLQKIRP-RIVIVEEAAEVLEAHIVTTLSPGC--QHLILIGDHQQLRP---SATVYELATHFHLEVSLFERLVRNGLPFVRLQYQHRMRPEIARLLVPHIYTELRDHPSVLAYEDIKGMGTNLFFVEHSELEEEV----ADSRSRHNRHEARFVVALCRYLILQ---GYRPAQITVLTMYAGQLLALRRMMPRDPFQGVRVCVVDKYQGEENDIVLLSLVRSNAEGR------PGFLRNENRACVALSRAKRGLYVVGNAAMLAATVPL---WARLL 314          
BLAST of C2H2-type domain-containing protein vs. Ensembl Yeast
Match: SEN1 (ATP-dependent 5' to 3' RNA/DNA and DNA helicase; subunit of the exosome-associated Nrd1p complex that mediates 3' end formation of snRNAs, snoRNAs, CUTs and some mRNAs; helicase-independent role in transcription-coupled repair; coordinates replication with transcription, associating with moving forks and preventing errors that occur when forks encounter transcribed regions; homolog of Senataxin, implicated in Ataxia-Oculomotor Apraxia 2 and a dominant form of juvenile ALS [Source:SGD;Acc:S000004422])

HSP 1 Score: 65.0846 bits (157), Expect = 6.727e-11
Identity = 69/280 (24.64%), Postives = 128/280 (45.71%), Query Frame = 3
Query: 2358 FNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLR--KFSVPIICRLHNIYKLLKNYTITLREV-YRTHPAIVNYLSQAIYYETQL-------ISLMKPTYQIVPMM---FFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFD-QSKILVCSPFYAQVKLIRDRLR-------SKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRD 3134
            F+ + +DEA Q  E+ +I+  ++G  +   I  GD  Q  P + + +    K++  +  R+       KN +  L +V YR HP+I  + S   +Y+ +L       I   +P +Q+ P+    FFD  S    +    +    S+ N +E+++ +E V  L +      D   KI + SP+  Q++ +R           +KS++   ++     QG E +++ IS V + D  S +      F  +   +N+ ++RAK  + V+G + SL      RD
Sbjct: 1584 FDTVIIDEACQCTELSSIIPLRYGGKRC--IMVGDPNQLPPTVLSGAASNFKYNQSLFVRME------KNSSPYLLDVQYRMHPSISKFPSSE-FYQGRLKDGPGMDILNKRPWHQLEPLAPYKFFDIISGRQEQ----NAKTMSYTNMEEIRVAIELVDYLFRKFDNKIDFTGKIGIISPYREQMQKMRKEFARYFGGMINKSIDFNTID---GFQGQEKEIILISCVRADDTKSSV-----GFLKDFRRMNVALTRAKTSIWVLGHQRSLAKSKLWRD 1842          
BLAST of C2H2-type domain-containing protein vs. Ensembl Yeast
Match: HCS1 (Hexameric DNA polymerase alpha-associated DNA helicase A; involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities [Source:SGD;Acc:S000001500])

HSP 1 Score: 64.3142 bits (155), Expect = 7.624e-11
Identity = 105/474 (22.15%), Postives = 186/474 (39.24%), Query Frame = 3
Query: 2016 ILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIP-----RLVNGIKLIKSSHKRKG----AEKNTIFSD----------------------------------------ELTEEIFTNNRVFITTIENAAD-SLSMFFPILEKLSIFNYIFVDEAAQVLEVDA-IMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITL---REV-------YRTHPAIVNYLSQAIY----------YETQLISLMKPTYQI----------VPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQV----KLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTV-NPTRDQWSTFIEMCDEFANL 3179
            I++G  GTGKT    E +  +L    +  ILIC  S  + +  ++     +P     R+ +  +L+  S+KR      ++KNTI  D                                        +  +++   +R+ +TT+  ++   L   +       +F+ + +DE +Q +E    I +    N   K + AGD  Q  P +  +  +         +HN+   L +  I +   R++       YR +  I+ + S ++Y              LI L  PT             +P++++D+      E       L S  NE E+ IV E +  L   +SF+  ++ I V SP+ AQV    KLI D L+   L  + +      QG E DV+ +S V S++           F      +N+ ++R +  + V+G+   L    N     WS   E C+E A++
Sbjct:  226 IIHGPPGTGKTFTLIELIQQLLIKNPEERILICGPSNISVDTILERLTPLVPNNLLLRIGHPARLL-DSNKRHSLDILSKKNTIVKDISQEIDKLIQENKKLKNYKQRKENWNEIKLLRKDLKKREFKTIKDLIIQSRIVVTTLHGSSSRELCSLYRDDPNFQLFDTLIIDEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDKNV-------IHNLETTLFDRIIKIFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLIDL--PTVDATPSEDDDDTKIPLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENL---RSFNVPENSIGVISPYNAQVSHLKKLIHDELK---LTDIEISTVDGFQGREKDVIILSLVRSNEK------FEVGFLKEERRLNVAMTRPRRQLVVVGNIEVLQRCGNKYLKSWS---EWCEENADV 674          
BLAST of C2H2-type domain-containing protein vs. Ensembl Nematostella
Match: EDO45137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTS2])

HSP 1 Score: 133.65 bits (335), Expect = 2.377e-31
Identity = 118/433 (27.25%), Postives = 189/433 (43.65%), Query Frame = 3
Query: 2010 PFILNGAFGTGKTLVFAETVMAILEAELKSS-----ILICTRSYSAGELYMQIF-------QKYIPRLVNGIKLIKSSHKRKGAEKNTIFS----DELTEEIFTNNR-------VFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSV--PIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKN----KSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSS--------DDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL*INYIL 3197
            P ++ G FGTGKT   AE V  +      ++     ILICT S SA + Y+  +        +  P L   ++ I   H+   +  +T+      D  T      +R       V +TT+  A   + M  P       F+++F+DEAAQ +E + ++        T+ + AGD  Q    +++   R+  +   ++ RL+ +Y    +  + L E YR +  IV   S+  Y  T +    +P     P+ F      L  E +  D+   S+ N  E   V E V EL+K      +   +  +I V +P+ AQV+ IR  LR   L  V VE  +N+QG E+D +FISTV ++        D+       H  F S+  L+N  V+RAK+ + ++GD  +L      +  W      C E      NY L
Sbjct:  468 PLLIFGPFGTGKTRTIAEAVKELCRLHAGNTAANLRILICTHSNSAADHYIVDYLHPFVTSSEIGPFLCRPLR-ICWEHRFFSSVSHTVLKYCLIDRETGRFAIPSRQDIDCVSVIVTTLVTADVLVKMGLPS----GYFSHVFIDEAAQAMEAETLIPLCLTQQSTRIVLAGDHLQMGAHVFSPVARRLCLDRSLLVRLYELYPRESDSKLLLLENYRAYNDIVEIPSKLFYEGTLIAHKHRPEGSEYPIRFH---GVLGREERAVDR--ASYYNMAEAAEVSERVEELVKQWRGEDAEDVELRRICVLTPYTAQVREIRQLLRRSQLGEVRVESVNNVQGLEFDALFISTVHTAFGLTPEMLDNH------HLGFLSDPRLLNTAVTRAKYHLTIVGDPNALCGAGKCKACWKIIFSKCSEHGTF--NYRL 882          
BLAST of C2H2-type domain-containing protein vs. Ensembl Nematostella
Match: EDO34496 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP82])

HSP 1 Score: 100.138 bits (248), Expect = 1.088e-21
Identity = 124/529 (23.44%), Postives = 221/529 (41.78%), Query Frame = 3
Query: 1764 VEASIYFSYSRLLFDRRHASLN---NVPKYDKLSYNPLTSPFFTRLPYGEDESTI-VFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKY--IPR---------------LVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVD-----AIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVP------IICRLHNIYKLLKNYTITLREV-----------YRTHPAIVNYLSQAIYYETQLISLMKP-------TYQIVPM----MFFDSSSTLSNEIQVFDKDL-----CSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDD----DSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMC 3161
            ++  + F+++R      H +L    +V K  +LS N   +      P  +D+    +F  K   N+EQ++  + +++         P+++ G  GTGKT+   E++  +L     S +L C  S SA +L ++   K+  IP+               L + IK++   H     + +  F  +  EEI  N R+ + T+  A   +S   P       F ++F+DE+ Q LE +     A ++        + + AGD  Q  P L +    K+ +       ++ R+    ++ ++    L E            YR+HPAI+  L   ++Y+ +L +            +  +P     + FD          V  KDL      SF N +E   VV+ + +L  ++      ++I V SP+  QV  IR  L   ++  + V      QG E  V+ ISTV SS +    D+   +    F +NR   N+ ++RA+  + V+G+   L   +     W  FI  C
Sbjct:    1 MKVQVRFTFTRTPLKLMHRALELPCDVIKMRQLSDNQQGAAIHHLPPLCDDDKVKRLFDVKLEDNQEQRQAVVSIVKGTSRPH---PYLIFGPPGTGKTITVVESIKQVLHVFPNSKVLACAPSNSAADLILERVMKHNVIPKMKMLRLNAFGRSYASLSDSIKVVSCIH-----DGDFFFPGK--EEIM-NKRLVVCTLVTAGRLVSADIPDTH----FTHVFIDESGQALEPECMVPLAGLLNPENPGGGQLVLAGDPQQLGPVLRSPLAIKYGLRMSLLERLMTRVAAYGRITEDEEDELGEYEPAMLTKLLKNYRSHPAILE-LPNGMFYDDELETCADKLKRESLCNWSKLPTKGFPILFDG---------VLGKDLREGKSPSFFNPEEAATVVKHIKDLRDSRGVRVLMAEIGVISPYRQQVSKIRQLLHKNNITGIKVGSVEEFQGDERRVIIISTVRSSQEFLKMDAQFKL---GFLNNRKRFNVAITRAQALLIVVGNPHVLCKDS----HWGRFIHYC 497          
BLAST of C2H2-type domain-containing protein vs. Ensembl Nematostella
Match: EDO45106 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTX4])

HSP 1 Score: 91.2781 bits (225), Expect = 3.641e-19
Identity = 108/444 (24.32%), Postives = 184/444 (41.44%), Query Frame = 3
Query: 1935 NNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELY-MQIFQKYIPRLVNGIKLIKSSHKRKGAEK-NTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIM-VYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFS--VPIICRL---------------HNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISL-------------MKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHP-TFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQ-WSTFIEMC 3161
            + LNE Q+     V R +       P++L G  GTGKT+   E ++ +      S ++ C  S SA +L  +++ +    +  + I+L      ++  E  N    D  + ++  + R+ + T   A    S+      K   F ++FVDEA Q  E + ++ +        + I AGD FQ  P L +     +   V ++ RL               H  Y  L      L   YR+HP+++  L  A++Y ++L                M PT Q  P++F      L  E  + + +  S+ N  E   VV  V  L  + +     + + + +P+  QV+ IR  L    ++ V V      QG E   + ISTV S++   G  + H   F  N    N+ V+RA+  + V+G+   L      RD  W + ++ C
Sbjct:   14 SRLNERQRAA---VARILSGQSRPTPYLLFGPPGTGKTVTLVEAILQVFHRVPSSRVIACAPSNSAADLMAVRLHRSGFIQEGDMIRLNAFQRVQEIPESINKYCVDTDSLQLAAHYRIIVCTCSTAGQLFSLGL----KPGHFTHVFVDEAGQATEPECLIPIGLAAGEDGQIILAGDPFQLGPVLRSPVAISYGLNVSLLERLMSGLLYARDETRFVDHGCYDPL--LVTKLVNNYRSHPSLLR-LPSALFYHSELRVCAERTMREQLSQWEMLPT-QGTPLVFHG----LKGE-DMREGNSPSWFNPVEAVQVVRYVQALKNSATCPIKLADLGIITPYKKQVEKIRLLLSRVGIDEVKVGSVEEFQGQERPAIIISTVRSTEAMVGFDVAHTIGFLDNPKRFNVAVTRAQSLLVVVGNPHVL-----CRDPYWCSLLQYC 436          
BLAST of C2H2-type domain-containing protein vs. Ensembl Medaka
Match: helz (helicase with zinc finger [Source:NCBI gene;Acc:101160963])

HSP 1 Score: 191.815 bits (486), Expect = 4.860e-49
Identity = 224/815 (27.48%), Postives = 363/815 (44.54%), Query Frame = 3
Query:  936 IYLRDDESRPFFKLIKANQN---QTVEHRSQLLTVCLKDNQFP------CVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQ---EVKYKNYVPFNMSETTCRGVLSEELLGSIFKIIPNRDWIKT------TVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSS---GLIPANDGKLFGDVKFGRHHDQ---AAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEY--ESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNN--------LNEEQKKLPILVLRKIDTSEIALPFILN-GAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIF-QKYIP---------RLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDD---------------DSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            I L  D  RP F +   +     QTV    Q  T   +    P      C+ +  + FS     T+RQ I FD  +   E    + I VD  S E LE+L ++  R + +IT    +   K  V F+ +ET   G L   LL S ++I  + D + T      T+   NY   + D++ +EE+ Q   +SK   +  + + N  M +    G   A +G+LF   K      +   A R ++ K  S   +   +  +       V    YE   E ++ + + +   K   E + +++   ++  + F  +RL     H +L      D++  N +  P  T +P      TI + P           LN +QK+  + +   I    I+LP IL  G +GTGKT   A+ V  IL  +  S +LICT S SA +LY++ +   Y+          R+    + +K+ H     +   I S ++T ++ T   +    I     S S +   L+    +F +I +DEAAQ +E + IM +   +  T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+  Y    + S  +P+++   P+ FF +         V +K+  ++ N  EV  +VE V EL K    ++   D   I V SP+  QV  IR  LR K ++ V VE+  N+QG ++ V+F+STV +                  +     L   F SN  L+N  ++RA+  VAV+GD ++L +V   R  W  FI +C E A+L
Sbjct:  277 IALLYDAHRPHFFITGVSAEERLQTVPKGCQEWTPGEETAGAPDNGLDQCIYKVAVGFSTEIFGTFRQTIVFDFGS---EPVLMQRIMVDAASIEDLEHLLAA--RQQLLITAKRWDSSCKTIVEFSPNETM--GELERSLL-SRYQIPLSADQLFTQSVLDKTLTKDNYQARLHDLLYIEEIAQYKEVSKFNIKVNLQLVNSFMLTGISVGAKYAQNGQLFARFKLTETLSEDTLAGRLVMTKVNSVLLLPLSRDGVSSQPPPGVKERVYEAVIEEKTKDYIFLRICKNCCEELGLQSDRELQVELQFQLNRLPLCEMHYAL------DRIKDNCILFPDVTMVP------TIPWSPNRQWDEQLDPRLNAKQKEAILAITTPIS---ISLPPILIIGPYGTGKTFTLAQAVKHILRQD-NSRVLICTHSNSAADLYIKDYLHPYVEAGNAHARPLRVYFRNRWVKTVHPLV-QQYCLISSTQVTFQMPTREDILRHRIVVVTLSTSQYLCQLDLDPGLFTHILLDEAAQAMECETIMPFALASKSTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPSEYPCRILLCENYRSHEAIINYTSELFYDGKLMASGKQPSHKDFYPLTFFTARGE-----DVQEKNSTAYYNNAEVFEIVERVEELRKKWPVAWGKLDDGSIGVVSPYADQVFRIRAELRKKRMHEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAIKRKEQLVEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSVGRCRKFWEHFICICHENASL 1061          
BLAST of C2H2-type domain-containing protein vs. Ensembl Medaka
Match: helz (helicase with zinc finger [Source:NCBI gene;Acc:101160963])

HSP 1 Score: 189.119 bits (479), Expect = 3.820e-48
Identity = 217/784 (27.68%), Postives = 352/784 (44.90%), Query Frame = 3
Query: 1026 TVCLKDNQF-PCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQ---EVKYKNYVPFNMSETTCRGVLSEELLGSIFKIIPNRDWIKT------TVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSS---GLIPANDGKLFGDVKFGRHHDQ---AAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEY--ESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNN--------LNEEQKKLPILVLRKIDTSEIALPFILN-GAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIF-QKYIP---------RLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILE-KLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRK--FSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQ-IVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSF---DQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS----------------------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            T    DN    C+ +  + FS     T+RQ I FD  +   E    + I VD  S E LE+L ++  R + +IT    +   K  V F+ +ET   G L   LL S ++I  + D + T      T+   NY   + D++ +EE+ Q   +SK   +  + + N  M +    G   A +G+LF   K      +   A R ++ K  S   +   +  +       V    YE   E ++ + + +   K   E + +++   ++  + F  +RL     H +L      D++  N +  P  T +P      TI + P           LN +QK+  + +   I    I+LP IL  G +GTGKT   A+ V  IL  +  S +LICT S SA +LY++ +   Y+          R+    + +K+ H     +   I S ++T ++ T   +    I     S S +   L+    +F +I +DEAAQ +E + IM +   +  T+ + AGD  Q  P +Y++  R+    V ++ RL+  Y       I L E YR+H AI+NY S+  Y    + S  +P+++   P+ FF +         V +K+  ++ N  EV  +VE V EL K    ++   D   I V SP+  QV  IR  LR K ++ V VE+  N+QG ++ V+F+STV +                       D D G       F SN  L+N  ++RA+  VAV+GD ++L +V   R  W  FI +C E A+L
Sbjct:  338 TAGAPDNGLDQCIYKVAVGFSTEIFGTFRQTIVFDFGS---EPVLMQRIMVDAASIEDLEHLLAA--RQQLLITAKRWDSSCKTIVEFSPNETM--GELERSLL-SRYQIPLSADQLFTQSVLDKTLTKDNYQARLHDLLYIEEIAQYKEVSKFNIKVNLQLVNSFMLTGISVGAKYAQNGQLFARFKLTETLSEDTLAGRLVMTKVNSVLLLPLSRDGVSSQPPPGVKERVYEAVIEEKTKDYIFLRICKNCCEELGLQSDRELQVELQFQLNRLPLCEMHYAL------DRIKDNCILFPDVTMVP------TIPWSPNRQWDEQLDPRLNAKQKEAILAITTPIS---ISLPPILIIGPYGTGKTFTLAQAVKHILRQD-NSRVLICTHSNSAADLYIKDYLHPYVEAGNAHARPLRVYFRNRWVKTVHPLV-QQYCLISSTQVTFQMPTREDILRHRIVVVTLSTSQYLCQLDLDPGLFTHILLDEAAQAMECETIMPFALASKSTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPSEYPCRILLCENYRSHEAIINYTSELFYDGKLMASGKQPSHKDFYPLTFFTARGE-----DVQEKNSTAYYNNAEVFEIVERVEELRKKWPVAWGKLDDGSIGVVSPYADQVFRIRAELRKKRMHEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAIKRKEQLVEDSTEDLDYG-------FLSNYKLLNTAITRAQSLVAVVGDPIALCSVGRCRKFWEHFICICHENASL 1084          
BLAST of C2H2-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000013379.2 (helicase with zinc finger 2 [Source:NCBI gene;Acc:101162116])

HSP 1 Score: 130.183 bits (326), Expect = 6.700e-30
Identity = 151/628 (24.04%), Postives = 273/628 (43.47%), Query Frame = 3
Query: 1386 NYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSS-GLIPANDGKLFG--DVKFGRHHDQAAREIIIKCVSNCYVA---FDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQI-FQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELT-----------------EEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYN-KSLRKFSVPIICRLHNIYK-----LLKNYTITLREVYRTHPAIVNYLSQAIYY-ETQLISL---MKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMC 3161
            NY  WM   +  EE  Q  I+S+L   G +T    LM    G+     G+LFG   V      D     ++ + +++  VA    D  +  ++E  ++     E +      + +  SKQ    + +K+SE  E  + F   R  F   H +++ +P   ++    L +     +P G     + F+    LN +Q+     +L   +  +   P ++ G FGTGKT   A T    L    ++ +LICT + S+ +LY++  F   I     G++ ++    ++G  +  + +DE+T                 ++    + + +TT   A     +  P       F +I +DEA+Q+LE +A++        T+ + AGD  Q  P+L++    R+    ++ RL + Y+       ++  I   + YR+   IV ++S   Y  +T +I     + P      + F       +  +  F     + +   EV  VV+ +LE   +     +Q  I + S   AQV  IR  L SK+   + VE  +N+QG ++  V ++TV + D    S +P L P F+  R ++N  ++RA+  V V+GD  +L +       W +FI+ C
Sbjct:  696 NYKEWMHHFLFAEEKAQDQIVSRLNICGELTTMEKLMHPKFGMEFPLQGELFGVISVPCKLTVDSPEGLVLKQSINSVLVAPVNTDHPQTKVYEASILPLKTKESQ------IHLRLSKQCCSDLALKSSETYEMEVQFQLDRYSFCIWHKAVDLLPDTTRV----LPNFGNCGVPVG----NVTFE---KLNPKQQLAVDFILGDCNGKKFVAPLLIYGPFGTGKTFTLA-TATRELCKHPQNKVLICTHTNSSADLYIRDHFHPIISSEKEGLQPLRIKANKQG--RALLTTDEITLKYCLLSKDKHQFLPPKKDDLDAHNIVVTTTSMAKHFHDLKLP----EGYFTHILIDEASQMLECEALLALDLAGSNTRIVLAGDHMQMGPQLFSVDDDRRSDHTLLTRLFHYYQGQLCDAAQSSRIIFSDNYRSTKEIVEFVSTHFYVGKTNVIKAAGDVSPPANNHALRFHHVRGDCA--LDRFSMSWWNMQEVVEVAKVVKDILEQWPSTWGQMEQRSICILSEG-AQVWKIRQAL-SKTFPEINVETLANVQGKQFRAVIMTTVQTRDSLQSSHLPGL-PLFNDAR-VLNTAMTRAQSLVVVVGDAAALCSFGKCSGIWKSFIDHC 1293          

HSP 2 Score: 82.4185 bits (202), Expect = 2.487e-15
Identity = 74/280 (26.43%), Postives = 126/280 (45.00%), Query Frame = 3
Query: 2334 PILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTY-------QIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLS-------SDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTR 3131
            P L +      I +DE A   E  A++     N   K +  GD  Q RP + N+S++K  +          +L +   + L   YR H  I  + S+  +YE +L + ++P         +++P++F D        +    K   + K   E +  V  ++ +L NK+   +Q  I+V SP+ AQV  IR+ L   +L ++ V   +  QG E+  V +STV S        + D G    H  F  + N IN+ ++RAK  + +IG++  L   +  R
Sbjct: 2585 PSLSRSVSARQILIDECAMATEPQALIPL-VCNKPEKVVLIGDHKQLRPIVKNESVKKLGMSRSLFESYFNQLSEKKAVMLDTQYRMHEDICEFPSEK-FYEGKLKTAVEPAASVLRVDGKVMPVVFGDIEGVTIKLVVKTSKGNNNSKANYEERDQVVRIVTMLVNKA-KVEQRSIVVLSPYNAQVSEIREELGKNNLKQITVTTITKSQGSEWRYVILSTVCSLSSKEIVREPDGGWLSKHIGFVGDPNQINVGITRAKEGLCIIGNQKLLACSSTWR 2861          
BLAST of C2H2-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000034865.1 (putative helicase mov-10-B.2 [Source:NCBI gene;Acc:101175667])

HSP 1 Score: 95.5153 bits (236), Expect = 1.800e-19
Identity = 117/462 (25.32%), Postives = 199/462 (43.07%), Query Frame = 3
Query: 1929 PKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIK------LIKSSHKRKGAEKNTIFSDELTEEIFTNN-------RVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIM-VYQFGNYKT-KFIFAGDIFQTRPELYNKSL--RKFSVPIICRL---------HNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQL-----ISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELL----KNKSFSFDQSKILVCSPFYAQVKLIRDR------LRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLI----------NLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMC 3161
            P+   N EQ+K    +LR+  T++ A  ++L G  GTGKTL   + +M I++A+   +IL+C  S SA +    I +K +  LV+  K      L+ S  K     K     D+    I   N       ++ +TT++ A   ++   P       + YIFVDEA Q  E ++++ +    +  T + + AGD  Q  P + +K+       V ++ RL         H  +    N+   L + YR+HPAI+  +   ++Y  +L     +S +    +++P   F         I   +K   SF N  E++++ E +  L+    +N        +I + SP+  QV+ I+        L  ++L  V V      QG E+ V+ +STV             P     +N I          N+ ++RA+  + V+GD   L     T   W+TFI  C
Sbjct:  390 PRFEFNPEQQKAVTHILRR--TAKPAA-YLLCGPPGTGKTLTLVKAIMEIVKAQ-DINILVCAPSNSASD---DICEKILKGLVDTDKVYRLYPLLHSIAKIPEILKKNCNLDQKKGTIKIPNKKSIMSRKILVTTLQTAGRLVTGGIPPKH----YTYIFVDEAGQATETESMIPIAGLCDRSTCQVVLAGDPKQLGPVVISKTAEYHGLGVSLLERLMRDNDLYKPHEDFGFDSNFITKLLKNYRSHPAILK-VPNDLFYGGELQPCARLSKLYNQLELLPKEGFPVVFHGVAGISQQEKGFSSFYNMAEIEVIKEYLKSLIQHLHRNNVSHVPPGEIGIISPYRKQVEKIQKAIQWDADLSKENLENVEVGTVDKFQGKEFSVILMSTVRC----------FPKLKHKQNFILGFIRDDRRFNVAMTRARSLLVVVGDPRLLA----TDKNWNTFIHYC 825          
BLAST of C2H2-type domain-containing protein vs. Ensembl Medaka
Match: MOV10 (Mov10 RISC complex RNA helicase [Source:NCBI gene;Acc:101175158])

HSP 1 Score: 88.9669 bits (219), Expect = 2.108e-17
Identity = 105/434 (24.19%), Postives = 184/434 (42.40%), Query Frame = 3
Query: 2010 PFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDEL--------------TEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAI--MVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKF--SVPIICRLHNIYKLL--------KNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPT-------YQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELL----KNKSFSFDQSKILVCSPFYAQVKLIRDRL-------RSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDD----DSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDE 3167
            P+++ G  GTGKT+   E +  I + +    IL C  S SA +L      +++ R     ++  +S   K      +  D L              ++E     ++ +TT+  A   +S   P+      F ++FVDEA   +E + +  +   F     + + AGD  Q  P L +    K+   V ++ RL N + L         K +   L   YR+HPAI+  +   ++Y+ +L    +         ++ +P M F         +   +K   SF N  E++++++ V +LL    K         +I + +P+  QV+ IR  L       R   +N + V      QG E  V+ +STV SS +    D    +    F  N    N+ V+RAK  + V+G+ + L T +PT   W+ F++ C +
Sbjct:  544 PYLVFGPPGTGKTVTVVEAIKQIEKFQTCCHILACAPSNSAADLLCTKILEHVDRH-KVYRMYATSRDPK------LVPDHLKDVSNLVGECYEFPSKETLMEYKILVTTLLTAGRLVSGAIPV----GHFTHVFVDEAGHAVETECLVPIAGLFDASFCQLVLAGDPKQLGPILRSPFALKYGMGVSLLERLMNNFPLYQKNEGDYNKRFVTKLLRNYRSHPAILK-IPNDLFYDGELQPCAEEYSCSSYCFWRHLPKMEFPVIFHGVAGLDEREKTSPSFFNVAEIEVLMDYVQKLLEAQGKKGEPKIAPKEIGIIAPYRKQVQKIRRALEKVGQNFRLLDMNALKVGSVEEFQGQERRVILVSTVRSSSEYMEFDKKFSL---GFVKNEKRFNVAVTRAKALLIVVGNPVVLKT-DPT---WARFLQYCKD 958          
BLAST of C2H2-type domain-containing protein vs. Planmine SMEST
Match: SMESG000032119.1 (SMESG000032119.1)

HSP 1 Score: 1939.08 bits (5022), Expect = 0.000e+0
Identity = 943/948 (99.47%), Postives = 946/948 (99.79%), Query Frame = 3
Query:  336 MRNNNKFRISQLYKEFIEPYIYIPSTDNVSIRPITPVTHQQMPIYKINQVPQSKIENEIIHQEEKRKHYLCWFCLKDIASENSIPLHIESQPHKAKYDADKKRQWYFKMPCSQIALRSSDVNQNGITNQIDDEYLEMCARIKFREFLSSYTYEHIERKINPWPKFMEFKIPFFPSNIKCYKSPIQIFPTLSISLRCHKLAIYLRDDESRPFFKLIKANQNQTVEHRSQLLTVCLKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEVKYKNYVPFNMSETTCRGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSSGLIPANDGKLFGDVKFGRHHDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 3179
            MRNNNKFRISQLYKEFIEPYIYIPSTDNVSIRPITPVTHQQMPIYKINQVPQSKIENEIIHQEEKRK+YLCWFCLKDIASENSIPLHIESQPHKAKYDADKKRQWYFKMPCSQIALRSSDVNQNGITNQIDDEYLEMCARIKFREFLSSYTYE IERKINPWPKFMEFKIPFFPSNIKCYKSPIQIFPTLSISLRCHKLAIYLRDDESRPFFKLIKANQNQTVEHRSQLLTVCLKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQE+KYKNYVPFNMSETTCRGVLSEELLGS+FKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSSGLIPANDGKLFGDVKFGRHHDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNV KYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL
Sbjct:    1 MRNNNKFRISQLYKEFIEPYIYIPSTDNVSIRPITPVTHQQMPIYKINQVPQSKIENEIIHQEEKRKNYLCWFCLKDIASENSIPLHIESQPHKAKYDADKKRQWYFKMPCSQIALRSSDVNQNGITNQIDDEYLEMCARIKFREFLSSYTYERIERKINPWPKFMEFKIPFFPSNIKCYKSPIQIFPTLSISLRCHKLAIYLRDDESRPFFKLIKANQNQTVEHRSQLLTVCLKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEIKYKNYVPFNMSETTCRGVLSEELLGSVFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSSGLIPANDGKLFGDVKFGRHHDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVLKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL 948          
BLAST of C2H2-type domain-containing protein vs. Planmine SMEST
Match: SMESG000032117.1 (SMESG000032117.1)

HSP 1 Score: 824.698 bits (2129), Expect = 0.000e+0
Identity = 457/1023 (44.67%), Postives = 638/1023 (62.37%), Query Frame = 3
Query:  177 PFYANAKNPEEFVRDFQNGPINGSSLRVDRCKRKECDG----CSYAHNDFEFFIWNSMRNNNKFRISQLYKEFIEPYIYIPSTD-NVSIRPITPVTHQQMPIYKINQVPQSKIENEIIHQEEKRKHYLCWFCLKDIASENSIPLHIESQPHKAKYDADKKRQWYFKMP-------CSQIALRSSDVNQNGITNQIDDEYLEMCARIKFREFLSSY-------TYEHIERKINPWPKFMEFKIPFFPSNIKCYKSPIQIFPTLSI-SLRCHKLAIYLRDDESRPFFKLIKANQNQTVEHRSQLLTVCLKDNQFPCVVEFGIEFSPIYCSTYRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQ-EVKYKNYVPFNMSETT-CRGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWMRDMMVLEELEQRFILSKLIFEGPITIKNHLMTSSGLIPANDGKLFGDVKFGRHHDQAAREIIIKCVSNCYVAF---DKFKIFLFECELVDFFRYEYESRSIEGVSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKLSYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIENAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIFAGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQ-IVPMMFFDSSSTLSNEIQV-FDKDLCSFKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSD--DDSGIPILHPTFHSNRNLINLVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEM 3158
            P Y +AKNP+ F+RD+QN   N S      C R+ C+     C++AHND E+F+W  M NN +F+IS+++ ++ +P++Y+ S +  +S   +  +   QM  Y+   VPQ+  EN    +EE  K Y CWFC  +I+SE +I +H++ Q HK  Y+ADKKR+WYFKMP         Q +  S D      +   DDE  EM ARIKFR F S          Y    +K  PWP++++ K+P FPS I+CY  PIQ F TL I   R   L I+L+DDESRP+FKLI    NQ++++ +QLLT+        C VEF IEF  +Y STYRQ I F   ++    ++ + IRVDVG+  HLEN K  W++YK ++   +V+ +  +P+   E      +LSEE +  +  +  N  WI+TTV  HNY  WMRDMM+LEELEQR ILS+L F+  I I N +         +DGKLFG  +F  + D  +R++  +     Y      D  K   FE E+ +   Y +E+RSI+G ++C SK TVE + +K+   ++  I+  Y R  FD+RH SLN +P+YDKLSYNPL+ P FT LPYGEDEST+VF P  +LNEEQK+LP LVLRKI+T+EIALPF+LNGAFGTGKTL+ AETV  I  ++  + ILICTRS SA ++Y++IF + +    N I +++S             ++E  + ++   RV ITT++ A+      F   +KL  F YIFVDEAAQVLEVDAI ++QFGN  +KF+FAGDI+QT  E+YNK L+KFS+PII RL+  Y  +  Y I L +VYRTHP IV +LS+AIY   +L SLM+PTY+ + PM F DS     +E Q  F+KDL  F+N+ EV+++   + +L+ +     ++  ILVCSPFYAQV LIR +L + +   V VE PS IQG E+  VF+STVL+S+  D+    +LHPTFH ++NLIN+V+SRAKH V V+GD + L   + T  +W+ F+E+
Sbjct:   48 PIYVSAKNPKHFIRDYQNNSANRSKTP-SMCNREFCENFYQRCTFAHNDSEYFVWVRMVNNKEFKISEIFAKYFQPFVYVISNERKLSNHAVPSIRIHQMS-YQPITVPQTPEENMSKQKEENSKIYFCWFCRLNISSEKNIQVHLKGQSHKTNYEADKKRKWYFKMPDKNYLDNFCQHSPCSCD------SPHSDDELKEMIARIKFRHFFSKKYSTIIPENYLTSVKKFAPWPEWLQIKVPNFPSRIECYSHPIQTFVTLKICKCRFITLHIFLKDDESRPYFKLINTKNNQSLQYSNQLLTIENSPEVSECTVEFAIEFQALYSSTYRQNIAFQFISETNTVSYLRQIRVDVGTKNHLENFKEKWQKYKILLNHCQVEDRMLIPYKFDEDKFTTSILSEENINYVISMSANDKWIETTVGSHNYMTWMRDMMILEELEQRIILSRLNFQTKIKITNVIEIKDTYNYVHDGKLFGQFQFPSNQDILSRKLFTENSRKGYFTITEKDSLKR-RFEFEVANLLDYGFETRSIQGATLCLSKSTVENLQLKSGMELDIHIFMYYDRFHFDKRHKSLNKIPQYDKLSYNPLSCPSFTHLPYGEDESTVVFNPLKSLNEEQKRLPRLVLRKINTNEIALPFVLNGAFGTGKTLLIAETVRKIFVSDPGAHILICTRSASAADIYLEIFSRNVENHRNFITVVRSGR-----------TNEQLDVLYEKYRVLITTLDYASSWTKYEF---KKLKTFPYIFVDEAAQVLEVDAIGIFQFGNQHSKFVFAGDIYQTNAEIYNKDLQKFSIPIIRRLYKYYSKVVEYKICLNQVYRTHPKIVEFLSKAIYGSHELTSLMEPTYKSLSPMKFIDSH---IDEYQAQFNKDLGCFQNKNEVELIFIEISKLINDLRIQLNE--ILVCSPFYAQVTLIRRKLNAWNFGNVTVELPSGIQGKEFGFVFLSTVLTSEYLDNQ---VLHPTFHDSKNLINVVISRAKHSVVVVGDSIGLIASD-TWKEWTHFMEV 1038          
BLAST of C2H2-type domain-containing protein vs. Planmine SMEST
Match: SMESG000069873.1 (SMESG000069873.1)

HSP 1 Score: 93.2041 bits (230), Expect = 6.387e-19
Identity = 119/444 (26.80%), Postives = 191/444 (43.02%), Query Frame = 3
Query: 1938 NLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRV--FITTIENAAD------------SLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNY-KTKFIFAGDIFQTRPEL---YNKSLRK---FSVPIICRLHNIYKLLKNYTIT---------LREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQI---------VPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKS--FSFDQSKILVCSPFYAQV----KLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFH------------SNRNLINLVVSRAKHFVAVIGD 3098
            +LNE Q+   + V+R +      LP++L G  GTGKT+   E ++ + +    S IL+C  S SA +L          RL     L      R  A + +I S EL+++     RV  +  ++++ A+            S    + +  K     ++FVDEA Q  E + ++   F N    + I AGD  Q  P +   Y + L++     + + C L+   K +   + T         L + YR HPA++  L   ++YE  LI  +     I         VP++F         E++  +    S  N  E  +VV  +  LL++           I V +P+ AQV    KLI   L + +L ++ V      QG E +VV ISTV SS D+SG   +H +F             SN+   N+ ++RA   + VIGD
Sbjct:  583 SLNELQR---VAVVRILHGYSRPLPYVLFGPPGTGKTVTLVEAILQVYKNVASSRILVCAPSNSAADLLCL-------RLDESGVLETGEMVRMNAYRRSILS-ELSDKEPIPARVLPYCKSVDDLAEVAMYRIIICTCTSSGALYRLGLKTGHITHVFVDEAGQASEPEIMISLGFTNRCNGQIILAGDPMQLGPVIRSPYAQQLQESYLHRLLLTCDLYKKQKEICAGSTTHFNPLVVTQLLQNYRAHPALLK-LPSDMFYEGTLIPCVVKNRFINWKWLPNPEVPLVF---QGVRGKELR--NPRNPSTYNPSEAVMVVRWIGRLLQDTDNIGKLKDKNISVITPYRAQVDCIRKLISSCLDNVNLAKLKVASVEEFQGQENEVVIISTVRSSLDESGNNGVHESFAILNTVGSRLGFLSNKRRFNVSITRACSLLIVIGD 1009          
BLAST of C2H2-type domain-containing protein vs. Planmine SMEST
Match: SMESG000069873.1 (SMESG000069873.1)

HSP 1 Score: 92.8189 bits (229), Expect = 8.512e-19
Identity = 119/444 (26.80%), Postives = 191/444 (43.02%), Query Frame = 3
Query: 1938 NLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRV--FITTIENAAD------------SLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNY-KTKFIFAGDIFQTRPEL---YNKSLRK---FSVPIICRLHNIYKLLKNYTIT---------LREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQI---------VPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKS--FSFDQSKILVCSPFYAQV----KLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFH------------SNRNLINLVVSRAKHFVAVIGD 3098
            +LNE Q+   + V+R +      LP++L G  GTGKT+   E ++ + +    S IL+C  S SA +L          RL     L      R  A + +I S EL+++     RV  +  ++++ A+            S    + +  K     ++FVDEA Q  E + ++   F N    + I AGD  Q  P +   Y + L++     + + C L+   K +   + T         L + YR HPA++  L   ++YE  LI  +     I         VP++F         E++  +    S  N  E  +VV  +  LL++           I V +P+ AQV    KLI   L + +L ++ V      QG E +VV ISTV SS D+SG   +H +F             SN+   N+ ++RA   + VIGD
Sbjct:  657 SLNELQR---VAVVRILHGYSRPLPYVLFGPPGTGKTVTLVEAILQVYKNVASSRILVCAPSNSAADLLCL-------RLDESGVLETGEMVRMNAYRRSILS-ELSDKEPIPARVLPYCKSVDDLAEVAMYRIIICTCTSSGALYRLGLKTGHITHVFVDEAGQASEPEIMISLGFTNRCNGQIILAGDPMQLGPVIRSPYAQQLQESYLHRLLLTCDLYKKQKEICAGSTTHFNPLVVTQLLQNYRAHPALLK-LPSDMFYEGTLIPCVVKNRFINWKWLPNPEVPLVF---QGVRGKELR--NPRNPSTYNPSEAVMVVRWIGRLLQDTDNIGKLKDKNISVITPYRAQVDCIRKLISSCLDNVNLAKLKVASVEEFQGQENEVVIISTVRSSLDESGNNGVHESFAILNTVGSRLGFLSNKRRFNVSITRACSLLIVIGD 1083          
BLAST of C2H2-type domain-containing protein vs. Planmine SMEST
Match: SMESG000069873.1 (SMESG000069873.1)

HSP 1 Score: 92.8189 bits (229), Expect = 9.101e-19
Identity = 119/444 (26.80%), Postives = 191/444 (43.02%), Query Frame = 3
Query: 1938 NLNEEQKKLPILVLRKIDTSEIALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQIFQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRV--FITTIENAAD------------SLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNY-KTKFIFAGDIFQTRPEL---YNKSLRK---FSVPIICRLHNIYKLLKNYTIT---------LREVYRTHPAIVNYLSQAIYYETQLISLMKPTYQI---------VPMMFFDSSSTLSNEIQVFDKDLCSFKNEKEVKIVVEAVLELLKNKS--FSFDQSKILVCSPFYAQV----KLIRDRLRSKSLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFH------------SNRNLINLVVSRAKHFVAVIGD 3098
            +LNE Q+   + V+R +      LP++L G  GTGKT+   E ++ + +    S IL+C  S SA +L          RL     L      R  A + +I S EL+++     RV  +  ++++ A+            S    + +  K     ++FVDEA Q  E + ++   F N    + I AGD  Q  P +   Y + L++     + + C L+   K +   + T         L + YR HPA++  L   ++YE  LI  +     I         VP++F         E++  +    S  N  E  +VV  +  LL++           I V +P+ AQV    KLI   L + +L ++ V      QG E +VV ISTV SS D+SG   +H +F             SN+   N+ ++RA   + VIGD
Sbjct:  672 SLNELQR---VAVVRILHGYSRPLPYVLFGPPGTGKTVTLVEAILQVYKNVASSRILVCAPSNSAADLLCL-------RLDESGVLETGEMVRMNAYRRSILS-ELSDKEPIPARVLPYCKSVDDLAEVAMYRIIICTCTSSGALYRLGLKTGHITHVFVDEAGQASEPEIMISLGFTNRCNGQIILAGDPMQLGPVIRSPYAQQLQESYLHRLLLTCDLYKKQKEICAGSTTHFNPLVVTQLLQNYRAHPALLK-LPSDMFYEGTLIPCVVKNRFINWKWLPNPEVPLVF---QGVRGKELR--NPRNPSTYNPSEAVMVVRWIGRLLQDTDNIGKLKDKNISVITPYRAQVDCIRKLISSCLDNVNLAKLKVASVEEFQGQENEVVIISTVRSSLDESGNNGVHESFAILNTVGSRLGFLSNKRRFNVSITRACSLLIVIGD 1098          
The following BLAST results are available for this feature:
BLAST of C2H2-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HELZ1.978e-4626.92helicase with zinc finger [Source:HGNC Symbol;Acc:... [more]
HELZ1.212e-4527.21helicase with zinc finger [Source:HGNC Symbol;Acc:... [more]
HELZ1.866e-4427.09helicase with zinc finger [Source:HGNC Symbol;Acc:... [more]
HELZ21.775e-2523.61helicase with zinc finger 2 [Source:HGNC Symbol;Ac... [more]
HELZ24.609e-2024.37helicase with zinc finger 2 [Source:HGNC Symbol;Ac... [more]
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BLAST of C2H2-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
C05C10.26.043e-1025.32Uncharacterized ATP-dependent helicase C05C10.2 [... [more]
C05C10.26.575e-1025.32Uncharacterized ATP-dependent helicase C05C10.2 [... [more]
Y106G6D.51.161e-724.05pep chromosome:WBcel235:I:10119209:10121815:-1 gen... [more]
Y106G6D.51.268e-724.05pep chromosome:WBcel235:I:10119209:10122171:-1 gen... [more]
dna-22.345e-723.11Yeast DNA helicase/endonuclease family [Source:Un... [more]
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BLAST of C2H2-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG94252.421e-5023.65gene:FBgn0036451 transcript:FBtr0075693[more]
CG94252.421e-5023.65gene:FBgn0036451 transcript:FBtr0333075[more]
CG94252.421e-5023.65gene:FBgn0036451 transcript:FBtr0333074[more]
CG69671.648e-922.35gene:FBgn0034187 transcript:FBtr0300276[more]
CG69671.648e-922.35gene:FBgn0034187 transcript:FBtr0300277[more]
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BLAST of C2H2-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
helz3.519e-4325.48helicase with zinc finger [Source:NCBI gene;Acc:40... [more]
helz3.713e-4325.48helicase with zinc finger [Source:NCBI gene;Acc:40... [more]
helz22.765e-3424.23helicase with zinc finger 2, transcriptional coact... [more]
si:dkey-97a13.69.880e-2126.53si:dkey-97a13.6 [Source:ZFIN;Acc:ZDB-GENE-070912-6... [more]
mov10a3.580e-1623.80Mov10 RISC complex RNA helicase a [Source:ZFIN;Acc... [more]
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BLAST of C2H2-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
frmd71.124e-4326.49FERM domain containing 7 [Source:Xenbase;Acc:XB-GE... [more]
frmd72.577e-4326.49FERM domain containing 7 [Source:Xenbase;Acc:XB-GE... [more]
frmd75.157e-4326.49FERM domain containing 7 [Source:Xenbase;Acc:XB-GE... [more]
frmd76.749e-4326.49FERM domain containing 7 [Source:Xenbase;Acc:XB-GE... [more]
frmd77.349e-4326.49FERM domain containing 7 [Source:Xenbase;Acc:XB-GE... [more]
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BLAST of C2H2-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Helz4.832e-4326.98helicase with zinc finger domain [Source:MGI Symbo... [more]
Helz1.304e-4226.85helicase with zinc finger domain [Source:MGI Symbo... [more]
Helz7.702e-4226.85helicase with zinc finger domain [Source:MGI Symbo... [more]
Helz21.059e-2823.75helicase with zinc finger 2, transcriptional coact... [more]
Helz21.063e-2823.75helicase with zinc finger 2, transcriptional coact... [more]
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BLAST of C2H2-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P42694|HELZ_HUMAN8.959e-4427.09Probable helicase with zinc finger domain OS=Homo ... [more]
sp|Q6NYU2|HELZ_DANRE4.721e-4225.36Probable helicase with zinc finger domain OS=Danio... [more]
sp|Q6DFV5|HELZ_MOUSE5.387e-4126.85Probable helicase with zinc finger domain OS=Mus m... [more]
sp|E9QAM5|HELZ2_MOUSE7.434e-2823.75Helicase with zinc finger domain 2 OS=Mus musculus... [more]
sp|Q9BYK8|HELZ2_HUMAN8.523e-2523.61Helicase with zinc finger domain 2 OS=Homo sapiens... [more]
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BLAST of C2H2-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K1RFQ64.332e-5124.04Putative helicase with zinc finger domain OS=Crass... [more]
V3ZS156.336e-5125.55C3H1-type domain-containing protein (Fragment) OS=... [more]
W8BQS11.554e-4926.63Putative helicase with zinc finger domain (Fragmen... [more]
R7TV953.421e-4925.65Uncharacterized protein OS=Capitella teleta OX=283... [more]
A0A4Y2CFZ03.792e-4927.85Putative helicase with zinc finger domain OS=Arane... [more]
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BLAST of C2H2-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
helz1.880e-4324.62helicase with zinc finger [Source:NCBI gene;Acc:10... [more]
helz4.680e-4324.62helicase with zinc finger [Source:NCBI gene;Acc:10... [more]
helz22.874e-3425.28helicase with zinc finger domain 2-like [Source:NC... [more]
ENSAMXT00000014945.21.046e-1624.42Mov10 like RISC complex RNA helicase 1 [Source:NCB... [more]
mov10a4.267e-1623.36putative helicase mov-10-B.1 [Source:NCBI gene;Acc... [more]
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BLAST of C2H2-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000006694.12.473e-3225.16pep scaffold:Pmarinus_7.0:GL476853:158045:174859:1... [more]
ENSPMAT00000008661.11.420e-1124.65pep scaffold:Pmarinus_7.0:GL478401:184160:191851:-... [more]
ENSPMAT00000008666.12.416e-1125.44pep scaffold:Pmarinus_7.0:GL478401:184246:194592:-... [more]
ENSPMAT00000000979.16.281e-624.33pep scaffold:Pmarinus_7.0:GL478231:754:10442:1 gen... [more]
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BLAST of C2H2-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
SEN16.727e-1124.64ATP-dependent 5' to 3' RNA/DNA and DNA helicase; s... [more]
HCS17.624e-1122.15Hexameric DNA polymerase alpha-associated DNA heli... [more]
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BLAST of C2H2-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO451372.377e-3127.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO344961.088e-2123.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO451063.641e-1924.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of C2H2-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
helz4.860e-4927.48helicase with zinc finger [Source:NCBI gene;Acc:10... [more]
helz3.820e-4827.68helicase with zinc finger [Source:NCBI gene;Acc:10... [more]
ENSORLT00000013379.26.700e-3024.04helicase with zinc finger 2 [Source:NCBI gene;Acc:... [more]
ENSORLT00000034865.11.800e-1925.32putative helicase mov-10-B.2 [Source:NCBI gene;Acc... [more]
MOV102.108e-1724.19Mov10 RISC complex RNA helicase [Source:NCBI gene;... [more]
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BLAST of C2H2-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000032119.10.000e+099.47SMESG000032119.1[more]
SMESG000032117.10.000e+044.67SMESG000032117.1[more]
SMESG000069873.16.387e-1926.80SMESG000069873.1[more]
SMESG000069873.18.512e-1926.80SMESG000069873.1[more]
SMESG000069873.19.101e-1926.80SMESG000069873.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022398 ID=SMED30022398|Name=C2H2-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3296bp
TTTAATTGTAATTATTTATTAAATACATATTTTTATTATGTAACATTCCA
AGTATGACGGAAAAATATTATATTAAAGAATACTGTAAAATATGTTATCA
AAAAAAAAGGTATAATTTATTGAAACTAGAGAATAATGTAAAAAAATGTG
AAAGTTCGAACTGTAATAGTTCTAGTCCATTTTATGCGAATGCTAAAAAT
CCTGAGGAATTTGTTCGAGATTTTCAAAATGGTCCTATAAATGGTTCATC
ACTTAGAGTTGATAGATGTAAAAGGAAAGAGTGTGATGGTTGTTCATACG
CACATAATGATTTCGAATTTTTTATTTGGAATTCAATGAGAAATAATAAT
AAATTCAGAATCTCACAATTATACAAAGAATTTATCGAGCCATATATCTA
CATTCCTAGCACAGATAACGTTTCCATTCGTCCAATTACTCCGGTTACTC
ATCAACAAATGCCTATATATAAGATCAATCAAGTACCACAATCAAAAATA
GAAAATGAAATCATACATCAAGAGGAAAAAAGAAAACATTATCTCTGTTG
GTTTTGTTTAAAGGATATAGCCAGTGAAAATAGTATACCTTTGCATATTG
AAAGCCAACCACACAAAGCTAAATACGACGCAGATAAAAAACGTCAATGG
TATTTCAAAATGCCATGTTCACAAATTGCATTAAGAAGTTCTGATGTTAA
TCAAAACGGAATTACTAATCAAATTGATGATGAATATCTGGAAATGTGCG
CTAGAATTAAATTCCGAGAATTTCTGTCCTCATACACTTATGAGCACATT
GAAAGGAAGATAAATCCATGGCCTAAATTTATGGAATTCAAAATTCCATT
TTTCCCCAGTAACATTAAATGTTACAAATCTCCAATACAAATATTCCCTA
CATTATCAATCTCTCTTAGATGCCATAAGCTAGCCATTTATCTCAGAGAT
GATGAGTCCAGACCATTTTTCAAATTGATTAAAGCTAACCAGAATCAAAC
TGTGGAACATCGTAGCCAACTTTTGACAGTTTGTCTAAAAGACAACCAAT
TTCCATGTGTAGTCGAATTCGGTATTGAATTTAGTCCTATTTACTGTAGC
ACATATCGTCAACGAATAGAATTCGATTTGGAAACCGATAAAGGTGAATA
TACTTTTAGTAAAAGTATTCGAGTTGATGTTGGGTCAAATGAGCATCTTG
AAAATTTAAAAAGCTCTTGGGAAAGATATAAAGATGTGATAACTCAAGAA
GTCAAATACAAGAATTATGTCCCATTCAATATGTCAGAAACAACATGTCG
AGGAGTTTTGTCAGAAGAACTTCTAGGATCTATTTTCAAAATTATTCCAA
ATCGTGATTGGATTAAGACGACTGTTGAACATCATAATTATTGCAATTGG
ATGCGAGATATGATGGTGTTAGAAGAACTAGAACAACGCTTTATTTTGTC
AAAATTAATATTTGAAGGGCCAATAACTATTAAGAACCATCTTATGACAT
CTAGTGGTCTTATTCCTGCAAATGACGGGAAGCTCTTTGGTGATGTCAAA
TTTGGACGGCATCACGATCAAGCGGCCAGAGAAATCATTATCAAATGCGT
TTCGAATTGTTATGTTGCTTTTGATAAATTTAAAATTTTCCTATTCGAAT
GTGAATTGGTTGACTTTTTTCGTTATGAATATGAATCAAGATCTATTGAA
GGTGTGTCGATTTGTTTCTCAAAACAAACTGTGGAAACCGTTAATATTAA
GAACTCAGAGATAGTTGAGGCTTCTATTTATTTCAGTTATAGTCGATTAT
TATTTGATCGCCGACATGCATCTTTGAACAACGTTCCAAAATATGATAAA
TTATCATATAATCCTTTGACATCTCCATTTTTCACGAGGTTGCCTTACGG
AGAAGACGAATCGACAATTGTTTTCAAACCGAAAAACAACCTAAACGAGG
AACAAAAGAAACTTCCCATATTAGTTTTACGAAAAATTGATACATCTGAA
ATAGCTTTGCCGTTTATTCTCAATGGTGCTTTCGGTACCGGTAAAACCCT
GGTTTTTGCCGAAACCGTTATGGCGATTTTGGAAGCTGAACTTAAATCAT
CAATTTTAATTTGTACACGTTCATATTCTGCAGGAGAATTATATATGCAG
ATCTTTCAAAAGTATATCCCCAGGCTGGTTAATGGAATAAAATTAATAAA
AAGTTCACATAAAAGAAAAGGTGCTGAAAAAAATACAATTTTTAGTGATG
AATTGACCGAGGAAATATTTACTAATAATCGGGTTTTTATTACAACTATC
GAAAATGCAGCCGATTCGTTGTCGATGTTTTTTCCTATTTTGGAAAAGCT
TTCAATCTTCAATTATATATTTGTCGATGAAGCTGCTCAGGTACTTGAAG
TGGACGCCATTATGGTTTATCAATTCGGAAATTATAAAACAAAATTCATT
TTTGCTGGTGATATTTTTCAAACGAGACCAGAGCTTTATAACAAAAGTTT
GAGAAAATTTTCTGTTCCAATTATATGCAGATTGCACAATATTTATAAAT
TACTGAAGAATTACACGATTACCTTGAGAGAAGTGTACAGAACGCACCCA
GCAATTGTAAACTATTTATCCCAAGCAATTTATTATGAAACTCAGCTAAT
CTCTTTAATGAAACCGACTTATCAAATAGTGCCAATGATGTTTTTCGATT
CAAGTAGTACTTTATCCAATGAAATTCAAGTTTTCGATAAAGATTTATGT
TCTTTTAAAAATGAAAAAGAAGTTAAAATCGTTGTTGAAGCAGTTCTTGA
ATTATTAAAAAATAAAAGTTTTTCTTTTGATCAGAGTAAAATTTTAGTAT
GCTCACCTTTTTACGCACAGGTTAAATTGATAAGAGATCGATTGAGATCA
AAATCTTTGAACAGAGTGGTTGTTGAACAGCCGTCAAATATTCAAGGCTG
TGAATACGATGTGGTATTCATATCAACTGTACTTTCTAGCGATGATGACA
GCGGGATTCCGATTCTGCATCCGACATTTCATAGCAACCGGAATTTGATC
AATTTGGTTGTATCTAGAGCGAAGCATTTCGTTGCGGTTATTGGTGACAA
AATGTCCCTCACCACAGTCAATCCTACCAGAGATCAATGGTCGACATTTA
TTGAAATGTGTGATGAATTTGCAAATCTCTGAATAAACTATATTTTGTAA
TTGGTTTTTATTATATTATTTTCCGGCAACAAAATGGTGTTAGTTATATA
CGGCATTTGTTCTAATACAATCGAGGCTTTGATTGGTTTATATGGC
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protein sequence of SMED30022398-orf-1

>SMED30022398-orf-1 ID=SMED30022398-orf-1|Name=SMED30022398-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1043bp
MTEKYYIKEYCKICYQKKRYNLLKLENNVKKCESSNCNSSSPFYANAKNP
EEFVRDFQNGPINGSSLRVDRCKRKECDGCSYAHNDFEFFIWNSMRNNNK
FRISQLYKEFIEPYIYIPSTDNVSIRPITPVTHQQMPIYKINQVPQSKIE
NEIIHQEEKRKHYLCWFCLKDIASENSIPLHIESQPHKAKYDADKKRQWY
FKMPCSQIALRSSDVNQNGITNQIDDEYLEMCARIKFREFLSSYTYEHIE
RKINPWPKFMEFKIPFFPSNIKCYKSPIQIFPTLSISLRCHKLAIYLRDD
ESRPFFKLIKANQNQTVEHRSQLLTVCLKDNQFPCVVEFGIEFSPIYCST
YRQRIEFDLETDKGEYTFSKSIRVDVGSNEHLENLKSSWERYKDVITQEV
KYKNYVPFNMSETTCRGVLSEELLGSIFKIIPNRDWIKTTVEHHNYCNWM
RDMMVLEELEQRFILSKLIFEGPITIKNHLMTSSGLIPANDGKLFGDVKF
GRHHDQAAREIIIKCVSNCYVAFDKFKIFLFECELVDFFRYEYESRSIEG
VSICFSKQTVETVNIKNSEIVEASIYFSYSRLLFDRRHASLNNVPKYDKL
SYNPLTSPFFTRLPYGEDESTIVFKPKNNLNEEQKKLPILVLRKIDTSEI
ALPFILNGAFGTGKTLVFAETVMAILEAELKSSILICTRSYSAGELYMQI
FQKYIPRLVNGIKLIKSSHKRKGAEKNTIFSDELTEEIFTNNRVFITTIE
NAADSLSMFFPILEKLSIFNYIFVDEAAQVLEVDAIMVYQFGNYKTKFIF
AGDIFQTRPELYNKSLRKFSVPIICRLHNIYKLLKNYTITLREVYRTHPA
IVNYLSQAIYYETQLISLMKPTYQIVPMMFFDSSSTLSNEIQVFDKDLCS
FKNEKEVKIVVEAVLELLKNKSFSFDQSKILVCSPFYAQVKLIRDRLRSK
SLNRVVVEQPSNIQGCEYDVVFISTVLSSDDDSGIPILHPTFHSNRNLIN
LVVSRAKHFVAVIGDKMSLTTVNPTRDQWSTFIEMCDEFANL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0004386helicase activity
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000101muscle cell
PLANA:0003001lateral region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR041679DNA2/NAM7-like_AAA
IPR019791Haem_peroxidase_animal
IPR027417P-loop_NTPase
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR041679DNA2/NAM7 helicase-like, AAA domainPFAMPF13087AAA_12coord: 833..1016
e-value: 2.8E-20
score: 72.8
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 845..1042
e-value: 1.0E-28
score: 102.1
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 554..830
e-value: 1.1E-20
score: 76.1
NoneNo IPR availablePANTHERPTHR10887DNA2/NAM7 HELICASE FAMILYcoord: 592..1041
NoneNo IPR availablePANTHERPTHR10887:SF365HELICASE WITH ZINC FINGER DOMAIN-RELATEDcoord: 592..1041
NoneNo IPR availableCDDcd18808SF1_C_Upf1coord: 848..1036
e-value: 8.66409E-23
score: 94.6083
NoneNo IPR availableCDDcd18077DEXXQc_HELZcoord: 630..846
e-value: 9.9465E-22
score: 92.9334
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 629..1040