Synaptotagmin-2

Overview
NameSynaptotagmin-2
Smed IDSMED30022362
Length (bp)1443
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Synaptotagmin-2 (SMED30022362) t-SNE clustered cells

Violin plots show distribution of expression levels for Synaptotagmin-2 (SMED30022362) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Synaptotagmin-2 (SMED30022362) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Synaptotagmin-2 (SMED30022362) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30022362

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30022362h1SMcG0015048 SmedASXL_012014SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30022362h1SMcG0015048 dd_Smed_v4_12772_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30022362h1SMcG0015048 dd_Smed_v4_12772_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30022362h1SMcG0015048 Contig7493uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30022362h1SMcG0015048 Contig7493newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
dorsal ventral margin of the whole animalSMED30022362h1SMcG0015048 dd_Smed_v4_12772_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Human
Match: SYT2 (synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:11510])

HSP 1 Score: 95.9005 bits (237), Expect = 1.019e-20
Identity = 70/218 (32.11%), Postives = 104/218 (47.71%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++P FNE FTFK+ + EL    +   ++D+D+F    ++G++ +    ++    I    E  +DL+ GE +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K       PYFNE+F F  P   I    V V +           IG + +GS    T    HW  ML +PR P+A+WH L
Sbjct:  198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPI----EEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTVKKKTLN---PYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTE-LRHWSDMLANPRRPIAQWHSL 405
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Human
Match: SYT2 (synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:11510])

HSP 1 Score: 95.9005 bits (237), Expect = 1.019e-20
Identity = 70/218 (32.11%), Postives = 104/218 (47.71%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++P FNE FTFK+ + EL    +   ++D+D+F    ++G++ +    ++    I    E  +DL+ GE +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K       PYFNE+F F  P   I    V V +           IG + +GS    T    HW  ML +PR P+A+WH L
Sbjct:  198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPI----EEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTVKKKTLN---PYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTE-LRHWSDMLANPRRPIAQWHSL 405
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Human
Match: SYT1 (synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509])

HSP 1 Score: 95.5153 bits (236), Expect = 1.135e-20
Identity = 71/228 (31.14%), Postives = 111/228 (48.68%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW----------ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F    ++G+  +    ++       ++E  +DL+  E +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V V +           I ++F     +GY S G+E+       HW  ML +PR P+A+WH L
Sbjct:  201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVD----FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVF-----VGYNSTGAELR------HWSDMLANPRRPIAQWHTL 408
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Human
Match: SYT1 (synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509])

HSP 1 Score: 95.5153 bits (236), Expect = 1.135e-20
Identity = 71/228 (31.14%), Postives = 111/228 (48.68%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW----------ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F    ++G+  +    ++       ++E  +DL+  E +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V V +           I ++F     +GY S G+E+       HW  ML +PR P+A+WH L
Sbjct:  201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVD----FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVF-----VGYNSTGAELR------HWSDMLANPRRPIAQWHTL 408
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Human
Match: SYT1 (synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509])

HSP 1 Score: 95.5153 bits (236), Expect = 1.135e-20
Identity = 71/228 (31.14%), Postives = 111/228 (48.68%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW----------ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F    ++G+  +    ++       ++E  +DL+  E +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V V +           I ++F     +GY S G+E+       HW  ML +PR P+A+WH L
Sbjct:  201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVD----FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVF-----VGYNSTGAELR------HWSDMLANPRRPIAQWHTL 408
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Celegans
Match: snt-1 (Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:P34693])

HSP 1 Score: 93.9745 bits (232), Expect = 1.597e-20
Identity = 68/220 (30.91%), Postives = 102/220 (46.36%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFS--KDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE F FK+   E+    + F ++D+D+F     +GQ+ +    ++  ++I    + +   D KE E +   +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   + G + K           C   PY+NE+F F  P   I    + + +           IG   LG   N T   + HW  ML SPR P+A+WH L
Sbjct:  218 KTLNPVFNETFIFKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKIDLGAVIEEWKDIAPPPDDKEAEKS---LGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIVLMQGGKRLKKKKTSI---KKCTLNPYYNESFSFEVPFEQIQKVSLMITVMDYDKLGSNDAIGRCLLGC--NGTGAELRHWMDMLASPRRPIAQWHTL 427
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Celegans
Match: snt-1 (Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:P34693])

HSP 1 Score: 89.7373 bits (221), Expect = 3.957e-19
Identity = 71/223 (31.84%), Postives = 112/223 (50.22%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFS--KDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKI--KSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPK-PHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE F FK+   E+    + F ++D+D+F     +GQ+ +    ++  ++I    + +   D KE E +   +G +C  L     AG L V ILEAKNL+  +    S  +V +++  + RK   K KT+ K++T +      PYFNE+F+F K P   +    + + +           IG   LG   N T   + HW  ML SPR P+A+WH L
Sbjct:  218 KTLNPVFNETFIFKVAFNEITAKTLVFAIYDFDRFSKHDQIGQVLIPLGKIDLGAVIEEWKDIAPPPDDKEAEKS---LGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKLEMFGEDRKRLKKKKTNIKRKTLN------PYFNESFVFDKLPLHKMKKVSLMITVMDYDKLGSNDAIGRCLLGC--NGTGAELRHWMDMLASPRRPIAQWHTL 429
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Celegans
Match: snt-2 (Synaptotagmin 2 [Source:UniProtKB/Swiss-Prot;Acc:K8FE10])

HSP 1 Score: 84.3445 bits (207), Expect = 1.663e-17
Identity = 66/228 (28.95%), Postives = 108/228 (47.37%), Query Frame = 1 
Query:  715 IDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFP-KPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSE-MNMT----SGAIHWQSMLDSPRHPVAKWHVLTNPNVKE 1377
            ++P +NE F F I   EL+   +   V+DYD+   D  +GQL++  + ++     ++     K  K+ E     +G +C         G + +TI+EA+NL+  +    S  +V + +    HG K    SKK+T   +    PY+NE+F F  +PH  I    + V +W          IG V+LGS+ +N+     + +  W  M+ S R PV +WH L     KE
Sbjct:  144 LNPTYNETFQFSIPFNELHSKTLMLVVYDYDRLSKDDKMGQLSVPLESIDFGITTDIERPLQKPEKDDEKECR-LGDICFSTRYRPATGTVTLTIMEARNLKKMDVGGSSDPYVKIYL---HHGRKLL--SKKKTSRKYKTLNPYYNESFQFKIEPH-MIEKVHLIVSVWDYDKMSKNDFIGEVTLGSKHLNLPQITHACSEQWAEMMTS-RRPVVQWHTLQERMEKE 363
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Celegans
Match: snt-6 (SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:A0A0S4XQZ9])

HSP 1 Score: 76.6406 bits (187), Expect = 5.951e-15
Identity = 62/223 (27.80%), Postives = 110/223 (49.33%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILH-PELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLN-PSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPIC----IGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            ++++P FNE  +F+     +L+D  +  +V DYD+F +D  +G++ L  K +   SS +     + K L+    + +  G++ I L     +G + V+I++A++L  K+   +   +  VK+   + GNK +   K++T      P P FNE+F F  P   +   L  V + ++ M    I     IG+V +G  +    G  HW   ++ P  PVA WH L
Sbjct:  160 RNLNPTFNETLSFRGHSMKKLHDMTLVLQVMDYDRFSSDDPIGEILLPLKHVKFESSPV-----YWKHLQRPTVSKDACGEIMISLCYLPTSGKITVSIIKARDLHAKDRTRHYDTY--VKMWMVQQGNKLE---KRKTSVKPHTPSPIFNESFAFSIPVKQV--LLAEVNLVLTAMEYDVIGSNEEIGHVIVGG-LGSEHGQRHWSECVNHPEQPVAMWHKL 369
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Celegans
Match: snt-3 (SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5])

HSP 1 Score: 74.3294 bits (181), Expect = 1.469e-14
Identity = 63/219 (28.77%), Postives = 101/219 (46.12%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSK-DLKEGEDTSEGMGQVCIILN-SNGQAGLLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE FTFKI   E+    +   VFD+D+FG    +GQ+++      P   +++ +   + DL E    +  +G+VC+ L     +  L V ++E KNL+  + +  S  +V + +     G K     K   K       PY+NE+F F      +    + V +           IG V +G+    T  A+  W  ML +PR  VA+WH L
Sbjct:   74 KSLNPVFNESFTFKIPFNEIGGQTLVLNVFDFDRFGKHDQIGQISI------PLGKVDLAATLERTDLIESPPENR-LGEVCLALRYVPNKNKLSVVVMECKNLKKMDVLGLSDPYVKIYL---MMGTKRLEKKKTTIKMKTLN--PYYNESFSFDVTSEKMQRVHLHVTVSDYDRVGSNERIGQVIIGT--CATGVALKQWNDMLATPRRSVAQWHTL 278
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077726)

HSP 1 Score: 100.523 bits (249), Expect = 1.692e-22
Identity = 78/229 (34.06%), Postives = 113/229 (49.34%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKIL-HPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLK--EGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISD-CLVSVKIWISRM-FKMPI--CI-GYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPN 1368
            K + PVFNE FTFK L + +  +  + F +FD+D+F     +G++ +    ++ +  I    E  +DL   EGE   E +G +C  L     AG L V ILEAKNL+  +    S  +V + I   ++G + K      T    C   PY+NE+F F  P   I   CLV   +   R+    PI  CI G +  G+E+       HW  ML SPR P+A+WH L +P 
Sbjct:  251 KTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTI----EEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAI--MQNGKRLKKKK---TSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELR------HWSDMLASPRRPIAQWHTLKDPE 464
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077728)

HSP 1 Score: 100.523 bits (249), Expect = 1.749e-22
Identity = 78/229 (34.06%), Postives = 113/229 (49.34%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKIL-HPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLK--EGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISD-CLVSVKIWISRM-FKMPI--CI-GYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPN 1368
            K + PVFNE FTFK L + +  +  + F +FD+D+F     +G++ +    ++ +  I    E  +DL   EGE   E +G +C  L     AG L V ILEAKNL+  +    S  +V + I   ++G + K      T    C   PY+NE+F F  P   I   CLV   +   R+    PI  CI G +  G+E+       HW  ML SPR P+A+WH L +P 
Sbjct:  249 KTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTI----EEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAI--MQNGKRLKKKK---TSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELR------HWSDMLASPRRPIAQWHTLKDPE 462
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0345331)

HSP 1 Score: 100.523 bits (249), Expect = 1.749e-22
Identity = 78/229 (34.06%), Postives = 113/229 (49.34%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKIL-HPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLK--EGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISD-CLVSVKIWISRM-FKMPI--CI-GYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPN 1368
            K + PVFNE FTFK L + +  +  + F +FD+D+F     +G++ +    ++ +  I    E  +DL   EGE   E +G +C  L     AG L V ILEAKNL+  +    S  +V + I   ++G + K      T    C   PY+NE+F F  P   I   CLV   +   R+    PI  CI G +  G+E+       HW  ML SPR P+A+WH L +P 
Sbjct:  249 KTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTI----EEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAI--MQNGKRLKKKK---TSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELR------HWSDMLASPRRPIAQWHTLKDPE 462
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077727)

HSP 1 Score: 100.523 bits (249), Expect = 1.749e-22
Identity = 78/229 (34.06%), Postives = 113/229 (49.34%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKIL-HPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLK--EGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISD-CLVSVKIWISRM-FKMPI--CI-GYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPN 1368
            K + PVFNE FTFK L + +  +  + F +FD+D+F     +G++ +    ++ +  I    E  +DL   EGE   E +G +C  L     AG L V ILEAKNL+  +    S  +V + I   ++G + K      T    C   PY+NE+F F  P   I   CLV   +   R+    PI  CI G +  G+E+       HW  ML SPR P+A+WH L +P 
Sbjct:  249 KTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTI----EEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAI--MQNGKRLKKKK---TSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELR------HWSDMLASPRRPIAQWHTLKDPE 462
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0332218)

HSP 1 Score: 97.0561 bits (240), Expect = 2.647e-21
Identity = 75/227 (33.04%), Postives = 110/227 (48.46%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKIL-HPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISD-CLVSVKIWISRM-FKMPI--CI-GYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPN 1368
            K + PVFNE FTFK L + +  +  + F +FD+D+F     +G++ +    ++ +  I    E  +DL   E     +G +C  L     AG L V ILEAKNL+  +    S  +V + I   ++G + K      T    C   PY+NE+F F  P   I   CLV   +   R+    PI  CI G +  G+E+       HW  ML SPR P+A+WH L +P 
Sbjct:  251 KTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTI----EEWRDLVSVEGEGGQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAI--MQNGKRLKKKK---TSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELR------HWSDMLASPRRPIAQWHTLKDPE 462
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Zebrafish
Match: syt5a (synaptotagmin Va [Source:ZFIN;Acc:ZDB-GENE-040718-110])

HSP 1 Score: 101.679 bits (252), Expect = 5.124e-23
Identity = 75/220 (34.09%), Postives = 111/220 (50.45%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKM--PICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K++ PVFNE F FKI   +L    +  +VFD+D+FG   ++G++ +    +N   +   + E+ KDL  GE +  E +G +CI L     +G L V I+EAKNL+  +    S  F  VKI  + +G + K   KK+T        PYFNE+F F  P   I    V + ++         PI   ++  G+      G  HW  ML +PR PVA+WH L
Sbjct:  188 KNLCPVFNETFIFKIPFNDLAGQTLVLQVFDFDRFGKHDVIGEIKI---PMNSIDLGQPIHEY-KDLVGGEKEEQEKLGDICISLRYVPTSGKLTVCIMEAKNLKKMDVGGLSDPF--VKIVLQHNGKRIK---KKKTTVKQNTLNPYFNESFSFEIPFAQIQKVQVLITVYDYDKLGSNDPIGKCWIGFGAS---GVGLRHWSDMLANPRRPVAQWHTL 395
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Zebrafish
Match: syt1a (synaptotagmin Ia [Source:ZFIN;Acc:ZDB-GENE-040718-165])

HSP 1 Score: 93.9745 bits (232), Expect = 2.827e-20
Identity = 70/219 (31.96%), Postives = 109/219 (49.77%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F     +G + +    ++ S +    +E  +DL+  E +  E +G +C  L     AG L V +LEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V + +           IG V +G  +N T   + HW  ML +PR P+A+WHVL
Sbjct:  197 KTLNPVFNEQFTFKVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHV----TEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVITVLDYDKIGKNDAIGKVFVG--LNSTGTELRHWSDMLANPRRPIAQWHVL 404
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Zebrafish
Match: syt1a (synaptotagmin Ia [Source:ZFIN;Acc:ZDB-GENE-040718-165])

HSP 1 Score: 93.9745 bits (232), Expect = 2.827e-20
Identity = 70/219 (31.96%), Postives = 109/219 (49.77%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F     +G + +    ++ S +    +E  +DL+  E +  E +G +C  L     AG L V +LEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V + +           IG V +G  +N T   + HW  ML +PR P+A+WHVL
Sbjct:  197 KTLNPVFNEQFTFKVPYTELGGKTLVMTVYDFDRFSKHDAIGDVKVPMNKVDFSHV----TEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVITVLDYDKIGKNDAIGKVFVG--LNSTGTELRHWSDMLANPRRPIAQWHVL 404
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Zebrafish
Match: syt5b (synaptotagmin Vb [Source:ZFIN;Acc:ZDB-GENE-050522-134])

HSP 1 Score: 88.5817 bits (218), Expect = 1.353e-18
Identity = 75/219 (34.25%), Postives = 109/219 (49.77%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTIS--DCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K++ PVFNE F FKI + EL    +  +VFD+D+FG   ++GQ+ +    +N   +   L E+ ++L+ GE   E +G VCI L     AG L V I+EAKNL+  +    S  +V + +   +H  K     K   K       PYFNE+F F  P   I     L++V  +       PI   ++  G+      G  HW  ML +PR PVA+WH L
Sbjct:  192 KNLCPVFNETFIFKIPYAELGGKTLVLQVFDFDRFGKHDVIGQIKI---PMNCVDLAQPLHEW-RELENGEKEEEKLGDVCISLRYVPTAGKLTVNIMEAKNLKKMDVGGLSDPYVKIVL---QHNGKRLKKKKTTVKKNTLN--PYFNESFSFEVPFEQIQKVQLLITVYDYDKLGSNDPIGKTFIGYGA---TGVGLRHWSDMLANPRRPVAQWHTL 398
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Zebrafish
Match: syt5b (synaptotagmin Vb [Source:ZFIN;Acc:ZDB-GENE-050522-134])

HSP 1 Score: 88.9669 bits (219), Expect = 1.382e-18
Identity = 75/219 (34.25%), Postives = 109/219 (49.77%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTIS--DCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K++ PVFNE F FKI + EL    +  +VFD+D+FG   ++GQ+ +    +N   +   L E+ ++L+ GE   E +G VCI L     AG L V I+EAKNL+  +    S  +V + +   +H  K     K   K       PYFNE+F F  P   I     L++V  +       PI   ++  G+      G  HW  ML +PR PVA+WH L
Sbjct:  225 KNLCPVFNETFIFKIPYAELGGKTLVLQVFDFDRFGKHDVIGQIKI---PMNCVDLAQPLHEW-RELENGEKEEEKLGDVCISLRYVPTAGKLTVNIMEAKNLKKMDVGGLSDPYVKIVL---QHNGKRLKKKKTTVKKNTLN--PYFNESFSFEVPFEQIQKVQLLITVYDYDKLGSNDPIGKTFIGYGA---TGVGLRHWSDMLANPRRPVAQWHTL 431
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Xenopus
Match: syt8 (synaptotagmin 8 [Source:NCBI gene;Acc:100037878])

HSP 1 Score: 98.5969 bits (244), Expect = 7.158e-22
Identity = 72/242 (29.75%), Postives = 120/242 (49.59%), Query Frame = 1 
Query:  640 DPYVVVQVXXXXXXXXXXXXXXYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLK-EGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIK-SRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            DPY +V V + +  + +    + K ++PVFNE F FK+   E+  +    ++FD+++F    ++G++ +   ++N   +I    E  KDL   G+   E +G +C  L     +G L + ILEAKNL+  ++  +S  +V V +  +RK   + KT  KK T        PYFNE+F F      + +  + + +W          IG + LG   +  +   HW  ML  PR P+A+WH L
Sbjct:  142 DPYAIVYVTNDTRKKFETKVNR-KTLNPVFNESFVFKVTQEEVPRTTAVVQIFDFNRFLKHDVIGEMVIPLGEVNLQHVI----EDWKDLGPAGKTEHEHLGDICFSLRYVPSSGKLTIIILEAKNLKRMDSDGFSDPYVKVHLALNRKKWKRKKTAVKKSTLK------PYFNESFTFDVSLEQMKNLDLIISVWDHDKVGKNEQIGKLFLGCRAS-GNALRHWSDMLAHPRRPIAQWHKL 371
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Xenopus
Match: e2f4 (E2F transcription factor 4 [Source:Xenbase;Acc:XB-GENE-482721])

HSP 1 Score: 95.5153 bits (236), Expect = 1.293e-20
Identity = 72/229 (31.44%), Postives = 111/229 (48.47%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW----------ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLT 1359
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F    ++G + +    ++       ++E  +DL   E +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V V +           I ++F     +GY S G+E+       HW  ML +PR P+A+WH LT
Sbjct:  204 KTLNPVFNEQFTFKVPYAELGGKTLVLTVYDFDRFSKHDVIGDVKVPMNTVD----FGHVTEEWRDLVSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVF-----VGYNSTGAELR------HWSDMLANPRRPIAQWHTLT 412
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Xenopus
Match: luzp2 (leucine zipper protein 2 [Source:Xenbase;Acc:XB-GENE-940667])

HSP 1 Score: 93.9745 bits (232), Expect = 4.339e-20
Identity = 69/218 (31.65%), Postives = 105/218 (48.17%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++P+FNE FTFKI + EL    +   ++D+D+F    ++G++ +    ++    I    E  +DL+  E +  E +G +CI L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K       PYFNE+F F  P   I    V + +           IG + +G   + T    HW  ML +PR P+A+WH L
Sbjct:  204 KTLNPIFNETFTFKIPYQELGGKTLCMSIYDFDRFSKHDIIGEVKVPMNTVDLGQPI----EEWRDLQSAEKEEPEKLGDICISLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTVKKKTLN---PYFNESFSFEIPFEQIQKVQVVITVLDYDKLGKNEAIGKIFVGCNASGTE-LRHWSDMLANPRRPIAQWHPL 411
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Xenopus
Match: SYT5 (synaptotagmin 5 [Source:NCBI gene;Acc:100493612])

HSP 1 Score: 90.5077 bits (223), Expect = 5.448e-19
Identity = 67/219 (30.59%), Postives = 107/219 (48.86%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVL 1356
            K ++P FNE FTFK+ + EL    +   V+D+D+F     +G++ ++   ++ + +I    E  +DL+  E +  E +G +C  L     AG L V +LEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V + +           IG + +G   N T   + HW  ML +PR P+A+WH L
Sbjct:  194 KTLNPTFNESFTFKVPYAELGGKTLVMSVYDFDRFSKHDAIGEVRVHMNTVDLAHVI----EEWQDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVLTVLDYDKLGKNEAIGKIFVGC--NATGTELRHWSDMLANPRRPIAQWHTL 401
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Xenopus
Match: SYT5 (synaptotagmin 5 [Source:NCBI gene;Acc:100493612])

HSP 1 Score: 90.1225 bits (222), Expect = 6.081e-19
Identity = 67/219 (30.59%), Postives = 107/219 (48.86%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVL 1356
            K ++P FNE FTFK+ + EL    +   V+D+D+F     +G++ ++   ++ + +I    E  +DL+  E +  E +G +C  L     AG L V +LEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V + +           IG + +G   N T   + HW  ML +PR P+A+WH L
Sbjct:  199 KTLNPTFNESFTFKVPYAELGGKTLVMSVYDFDRFSKHDAIGEVRVHMNTVDLAHVI----EEWQDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVLTVLDYDKLGKNEAIGKIFVGC--NATGTELRHWSDMLANPRRPIAQWHTL 406
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Mouse
Match: Syt11 (synaptotagmin XI [Source:MGI Symbol;Acc:MGI:1859547])

HSP 1 Score: 95.9005 bits (237), Expect = 4.071e-21
Identity = 70/221 (31.67%), Postives = 111/221 (50.23%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTF-KILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAGLLVTILEAKNLRVKENMSYSHIFVTVKIK-SRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVS-VKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTN 1362
            K +DPVF+E FTF  I + +L D  + F V  +D+F  D ++G++ +    ++PS+    L+         +  S G  QV +      Q  + V +L+A++L   +    S  +V V +   RK   K KTH KK      C   P FNE+F++  P   + D  +  + I   R  K  + +G + LG+    TSGA HW+ + +SPR P+AKWH L+ 
Sbjct:  150 KTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQR-MTVVVLKARHLPKMDITGLSDPYVKVNVYYGRKRIAKKKTHVKK------CTLNPVFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEV-VGRLILGAHSVTTSGAEHWREVCESPRKPIAKWHSLSE 362
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Mouse
Match: Syt1 (synaptotagmin I [Source:MGI Symbol;Acc:MGI:99667])

HSP 1 Score: 95.9005 bits (237), Expect = 6.423e-21
Identity = 71/228 (31.14%), Postives = 111/228 (48.68%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW----------ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F    ++G+  +    ++       ++E  +DL+  E +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V V +           I ++F     +GY S G+E+       HW  ML +PR P+A+WH L
Sbjct:  200 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVD----FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVF-----VGYNSTGAELR------HWSDMLANPRRPIAQWHTL 407
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Mouse
Match: Syt1 (synaptotagmin I [Source:MGI Symbol;Acc:MGI:99667])

HSP 1 Score: 95.9005 bits (237), Expect = 6.423e-21
Identity = 71/228 (31.14%), Postives = 111/228 (48.68%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW----------ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F    ++G+  +    ++       ++E  +DL+  E +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V V +           I ++F     +GY S G+E+       HW  ML +PR P+A+WH L
Sbjct:  200 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVD----FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVF-----VGYNSTGAELR------HWSDMLANPRRPIAQWHTL 407
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Mouse
Match: Syt2 (synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666])

HSP 1 Score: 95.9005 bits (237), Expect = 7.040e-21
Identity = 70/218 (32.11%), Postives = 104/218 (47.71%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++P FNE FTFK+ + EL    +   ++D+D+F    ++G++ +    ++    I    E  +DL+ GE +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K       PYFNE+F F  P   I    V V +           IG + +GS    T    HW  ML +PR P+A+WH L
Sbjct:  201 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPI----EEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTVKKKTLN---PYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTE-LRHWSDMLANPRRPIAQWHSL 408
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Mouse
Match: Syt2 (synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666])

HSP 1 Score: 95.9005 bits (237), Expect = 7.040e-21
Identity = 70/218 (32.11%), Postives = 104/218 (47.71%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++P FNE FTFK+ + EL    +   ++D+D+F    ++G++ +    ++    I    E  +DL+ GE +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K       PYFNE+F F  P   I    V V +           IG + +GS    T    HW  ML +PR P+A+WH L
Sbjct:  201 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPI----EEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTVKKKTLN---PYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTE-LRHWSDMLANPRRPIAQWHSL 408
[Close]
BLAST of Synaptotagmin-2 vs. UniProt/SwissProt
Match: sp|Q5R4J5|SYT1_PONAB (Synaptotagmin-1 OS=Pongo abelii OX=9601 GN=SYT1 PE=2 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 6.937e-23
Identity = 73/228 (32.02%), Postives = 112/228 (49.12%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW----------ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F    ++G+  +    ++       ++E  +DL+  E +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K   KK T        PY+NE+F F  P   I    V V +           I ++F     +GY S G+E+       HW  ML +PR P+A+WH L
Sbjct:  198 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVD----FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLK---KKETTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVF-----VGYNSTGAELR------HWSDMLANPRRPIAQWHTL 405
[Close]
BLAST of Synaptotagmin-2 vs. UniProt/SwissProt
Match: sp|P21521|SY65_DROME (Synaptotagmin 1 OS=Drosophila melanogaster OX=7227 GN=Syt1 PE=1 SV=3)

HSP 1 Score: 100.523 bits (249), Expect = 1.696e-21
Identity = 78/229 (34.06%), Postives = 113/229 (49.34%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKIL-HPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLK--EGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISD-CLVSVKIWISRM-FKMPI--CI-GYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPN 1368
            K + PVFNE FTFK L + +  +  + F +FD+D+F     +G++ +    ++ +  I    E  +DL   EGE   E +G +C  L     AG L V ILEAKNL+  +    S  +V + I   ++G + K      T    C   PY+NE+F F  P   I   CLV   +   R+    PI  CI G +  G+E+       HW  ML SPR P+A+WH L +P 
Sbjct:  251 KTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTI----EEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIAI--MQNGKRLKKKK---TSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELR------HWSDMLASPRRPIAQWHTLKDPE 464
[Close]
BLAST of Synaptotagmin-2 vs. UniProt/SwissProt
Match: sp|P29101|SYT2_RAT (Synaptotagmin-2 OS=Rattus norvegicus OX=10116 GN=Syt2 PE=1 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 4.053e-20
Identity = 70/218 (32.11%), Postives = 104/218 (47.71%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++P FNE FTFK+ + EL    +   ++D+D+F    ++G++ +    ++    I    E  +DL+ GE +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K       PYFNE+F F  P   I    V V +           IG + +GS    T    HW  ML +PR P+A+WH L
Sbjct:  201 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPI----EEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTVKKKTLN---PYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTE-LRHWSDMLANPRRPIAQWHSL 408
[Close]
BLAST of Synaptotagmin-2 vs. UniProt/SwissProt
Match: sp|P46096|SYT1_MOUSE (Synaptotagmin-1 OS=Mus musculus OX=10090 GN=Syt1 PE=1 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 4.493e-20
Identity = 71/228 (31.14%), Postives = 111/228 (48.68%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW----------ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F    ++G+  +    ++       ++E  +DL+  E +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V V +           I ++F     +GY S G+E+       HW  ML +PR P+A+WH L
Sbjct:  200 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVD----FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVF-----VGYNSTGAELR------HWSDMLANPRRPIAQWHTL 407
[Close]
BLAST of Synaptotagmin-2 vs. UniProt/SwissProt
Match: sp|P47191|SYT1_CHICK (Synaptotagmin-1 OS=Gallus gallus OX=9031 GN=SYT1 PE=2 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 4.778e-20
Identity = 73/230 (31.74%), Postives = 113/230 (49.13%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQ--LALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW----------ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F    ++G+  +A+N  D         ++E  +DL+  E +  E +G +C  L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    + V +           I ++F     +GY S G+E+       HW  ML +PR P+A+WH L
Sbjct:  203 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEYKVAMNTVDF------GHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQIVVTVLDYDKIGKNDAIGKVF-----VGYNSTGAELR------HWSDMLANPRRPIAQWHTL 410
[Close]
BLAST of Synaptotagmin-2 vs. TrEMBL
Match: A0A093ESP2 (Synaptotagmin-1 (Fragment) OS=Gavia stellata OX=37040 GN=N328_04647 PE=4 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 3.105e-25
Identity = 79/246 (32.11%), Postives = 124/246 (50.41%), Query Frame = 1 
Query:  640 DPYVVVQVXXXXXXXXXXXXXXYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVK-IKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPNV 1371
            DPYV+V + S    + +    + K ++PVFNE FTF++   E+ +S +  +V+D+++F    ++G++ L    ++   +I   S+ +   K  E   E +G++C  L      G L+V ILEAK L+  ++   S  FV V  I +RK   K  T  KK T        PYFNE F+F  P   I +  V + +W          IG + LG      +   HW  ML +PR P+A+WH+L  P+V
Sbjct:   48 DPYVIVYLTSDMKKKHETKVYR-KTLNPVFNESFTFQVPQAEVPESTLVMQVYDFNRFAKHDIIGEVRLPLASVSLQHVIEQWSDLAVASKVEE---EQLGEICFSLRYVPSTGKLMVVILEAKKLKRMDSHGLSDPFVKVHLILNRKKWKKKTTSVKKNTLS------PYFNEVFVFEVPFNQIQNVDVVISVWDHDKVTKNEPIGKLFLGCRAT-GNQLRHWSDMLSNPRRPLAQWHILQPPDV 282
[Close]
BLAST of Synaptotagmin-2 vs. TrEMBL
Match: U3KB14 (Synaptotagmin 8 OS=Ficedula albicollis OX=59894 GN=SYT8 PE=4 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 6.224e-25
Identity = 79/246 (32.11%), Postives = 124/246 (50.41%), Query Frame = 1 
Query:  640 DPYVVVQVXXXXXXXXXXXXXXYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVK-IKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPNV 1371
            DPYV+V + S      +    + K ++P+FNE FTF++   E+++S +  +V+D+++F    ++G++ L    +N   +I   S+     K  E   E +G++C  L      G L V ILEAK L+  ++   S  FV V  I +RK   K +T  KK T +      PYFNE F+F  P   I +  V + +W          IG + LG      +   HW  ML +PR P+A+WH+L  P+V
Sbjct:  140 DPYVIVYLTSDMRKRYETKVYR-KTLNPIFNESFTFQVPQAEVSESTLVMQVYDFNRFAKHDIIGEVRLPLASVNLQHVIEQWSDLVVASKVEE---EHLGEICFSLRYVPSTGKLTVLILEAKQLKRMDSNGLSDPFVKVHLILNRKKWKKKRTSVKKNTIN------PYFNEVFVFEVPFSQIQNVDVVISVWDHDKVTKNEPIGKLFLGCRAT-GNQLRHWSDMLSNPRRPLAQWHILQPPDV 374
[Close]
BLAST of Synaptotagmin-2 vs. TrEMBL
Match: A0A218USQ3 (Synaptotagmin-1 OS=Lonchura striata domestica OX=299123 GN=SYT1_0 PE=4 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 8.366e-25
Identity = 78/246 (31.71%), Postives = 124/246 (50.41%), Query Frame = 1 
Query:  640 DPYVVVQVXXXXXXXXXXXXXXYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVK-IKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPNV 1371
            DPYV+V + S      +    + K+++P+FNE FTF++   E++ S +  +++D+++F    ++G++ L    +N   +I   S+ +   K  E   E +G++C  L      G L V ILEAK L+  ++   S  FV V  I +RK   K +T  KK T        PYFNE F+F  P   I +  V + +W          +G + LG      S   HW  ML +PR P+A+WH+L  P+V
Sbjct:  143 DPYVIVYLMSDIKKRYETKVYR-KNLNPIFNETFTFQVPQAEVSKSTLVMQIYDFNRFSKHDIIGEVRLPLASVNLQHVIKQWSDLAVASKVEE---EHLGEICFSLRYVPSTGKLTVLILEAKQLKRMDSDGLSDPFVKVHLILNRKKWKKKRTSVKKNTLS------PYFNEVFVFEVPFSQIQNVDVVISVWDHDKVTKNEPMGKLFLGCRAT-GSQLRHWSDMLSNPRRPLAQWHILQPPDV 377
[Close]
BLAST of Synaptotagmin-2 vs. TrEMBL
Match: A0A3M0JZ48 (Uncharacterized protein OS=Hirundo rustica rustica OX=333673 GN=DUI87_22809 PE=4 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 1.906e-24
Identity = 77/246 (31.30%), Postives = 122/246 (49.59%), Query Frame = 1 
Query:  640 DPYVVVQVXXXXXXXXXXXXXXYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVK-IKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPNV 1371
            DPYV+V + S      +    + K ++P+FNE F F++   E+++S +  +++D+++F    ++G++ L    +N   +I   S+     K  E   E +G++C  L      G L V ILEAK L+  ++   S  FV V  I +RK   K +T  KK T +      PYFNE F+F  P   I +  V + +W          IG + LG      +   HW  ML +PR P+A+WH+L  P V
Sbjct:  100 DPYVIVYLTSDVKRRYETKVYR-KTLNPIFNESFAFQVPQAEVSESTLVMQIYDFNRFAKHDIIGEVRLPLASVNLQHVIEQWSDLVVASKVEE---EHLGEICFSLRYVPSTGKLTVLILEAKQLKRMDSNGLSDPFVKVHLILNRKKWKKKRTSVKKNTLN------PYFNEVFVFEVPFSQIQNVDVVISVWDHDKVTKNELIGKLFLGCRAT-GNQLRHWSDMLSNPRRPLAQWHILQPPEV 334
[Close]
BLAST of Synaptotagmin-2 vs. TrEMBL
Match: A0A3P8XSZ3 (Synaptotagmin Va OS=Esox lucius OX=8010 PE=4 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 2.678e-24
Identity = 96/278 (34.53%), Postives = 143/278 (51.44%), Query Frame = 1 
Query:  532 SFGKIYFAXXXXXXXXXXXXXXXXXXNLPT-PIDDCLDPYVVVQVXXXXXXXXXXXXXXYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            +FGK+ F L Y   +  LIV +++ ENLP   +    DPYV V +      + +    + K++ PVFNE F FKI + EL    +  +VFD+D+FG   ++GQ+++    +N   +   L E+ +DL  GE +  E +G +CI L     AG L + I+EAK+L+  +    S  FV V ++ +  G + K   KK+T        PYFNE+F F  P G I    V V ++          IG V +G   +   G  HW  ML +PR PVA+WH L
Sbjct:  121 NFGKLEFTLDYNFTENQLIVGILQAENLPAMDMGGTSDPYVKVYMLPDKKKKFETKVQR-KNLCPVFNETFIFKIPYQELGGQTLVLQVFDFDRFGKHDVIGQISI---PMNSVDLAQPLHEW-RDLIGGEKEEQEKLGDICISLRYVPTAGKLTINIMEAKHLKAMDCGGLSDPFVKVVLQYQ--GKRLK---KKKTTVKQNTLNPYFNESFSFEIPFGQIQKVQVLVTVYDYDKLGSNDAIGKVWIGYGASGV-GLRHWSDMLANPRRPVAQWHAL 387
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Cavefish
Match: syt5a (synaptotagmin-2-like [Source:NCBI gene;Acc:103027827])

HSP 1 Score: 102.064 bits (253), Expect = 3.477e-23
Identity = 73/218 (33.49%), Postives = 108/218 (49.54%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K++ PVFNE F FKI   +L    +  +VFD+D+FG   ++G++ +    ++    I+      KDL  GE +  E +G +CI L     +G L V I+EAKNL+  +    S  FV V ++   +G + K   KK+T        PYFNE+F F  P   I    V + ++          IG   +G   +   G  HW  ML +PR PVA+WH L
Sbjct:  182 KNLCPVFNETFIFKIPFNDLAGQTLVLQVFDFDRFGKHDVIGEIKIAMNSIDLGQPIHEW----KDLVGGEKEEQEKLGDICISLRYVPTSGKLTVCIMEAKNLKKMDVGGLSDPFVKVVLQH--NGKRLK---KKKTTVKQNTLNPYFNESFSFEIPFAQIQKIQVLITVYDYDKLGSNDAIGKCWIGYGASGV-GLRHWSDMLANPRRPVAQWHTL 389
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Cavefish
Match: syt5a (synaptotagmin-2-like [Source:NCBI gene;Acc:103027827])

HSP 1 Score: 102.064 bits (253), Expect = 3.912e-23
Identity = 73/218 (33.49%), Postives = 108/218 (49.54%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K++ PVFNE F FKI   +L    +  +VFD+D+FG   ++G++ +    ++    I+      KDL  GE +  E +G +CI L     +G L V I+EAKNL+  +    S  FV V ++   +G + K   KK+T        PYFNE+F F  P   I    V + ++          IG   +G   +   G  HW  ML +PR PVA+WH L
Sbjct:  187 KNLCPVFNETFIFKIPFNDLAGQTLVLQVFDFDRFGKHDVIGEIKIAMNSIDLGQPIHEW----KDLVGGEKEEQEKLGDICISLRYVPTSGKLTVCIMEAKNLKKMDVGGLSDPFVKVVLQH--NGKRLK---KKKTTVKQNTLNPYFNESFSFEIPFAQIQKIQVLITVYDYDKLGSNDAIGKCWIGYGASGV-GLRHWSDMLANPRRPVAQWHTL 394
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Cavefish
Match: ENSAMXT00000017640.2 (synaptotagmin-1-like [Source:NCBI gene;Acc:103035847])

HSP 1 Score: 101.293 bits (251), Expect = 8.023e-23
Identity = 77/241 (31.95%), Postives = 120/241 (49.79%), Query Frame = 1 
Query:  640 DPYVVVQVXXXXXXXXXXXXXXYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVK-IKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            DPYV V V        +    + K ++PVFNE F ++I   EL +S +  +V+D+++F    ++G+L L    ++ + +I    + SK  K  +   E +G++C  L     A  L V ILEAKNL+  ++  YS  +V V+ I  ++   K KT  KK+T +      PYFNE+F F      I    + + +W          IG + LG +    +   HW  ML +PR PVA+WH L
Sbjct:  172 DPYVKVYVLPSKSKTFETKVFR-KTLNPVFNESFKYQISQKELGESTLVIQVYDFNRFSKHDVIGELRLELSAVDWNHVIEEWRDLSKPSKHEQ---EHLGEICFSLRYVPTASKLTVVILEAKNLKKMDHGGYSDPYVKVQLILDKRKWKKKKTSVKKQTLN------PYFNESFTFDVSFEQIQKVQLVISVWDHDKMSRNDAIGKIFLGCDAT-GNQLRHWADMLSNPRRPVAQWHTL 401
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Cavefish
Match: syt5b (synaptotagmin-1-like [Source:NCBI gene;Acc:103029888])

HSP 1 Score: 93.5893 bits (231), Expect = 3.400e-20
Identity = 75/228 (32.89%), Postives = 110/228 (48.25%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW----------ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K++ PVFNE F FKI + EL    +   V+D+D+FG   ++GQ+ +    +N   +   L ++ +DL+  E +  E +G VCI L     AG L V I+EAKNL+  +    S  FV + +   +H  K     K   K       PYFNE+F F  P   I    + + ++          I ++F     IGY + G       G  HW  ML +PR PVA+WH L
Sbjct:  221 KNLCPVFNETFIFKIPYAELGGKILVLLVYDFDRFGKHDVIGQIKI---PMNCVDLGQPLHQW-RDLESAEKEEQEKLGDVCISLRYVPTAGKLTVNIMEAKNLKKMDVGGLSDPFVKIVL---QHNGKRLKKKKTTVKKNTLN--PYFNESFSFEIPFEQIQKVQLLITVYDYDKLGSNDPIGKIF-----IGYGATG------VGLRHWSDMLANPRRPVAQWHTL 428
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Cavefish
Match: syt1b (synaptotagmin Ib [Source:ZFIN;Acc:ZDB-GENE-060503-166])

HSP 1 Score: 89.7373 bits (221), Expect = 4.872e-19
Identity = 67/217 (30.88%), Postives = 100/217 (46.08%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++P FNE FTFK+ + EL    +   V+D+D+F     +G + +    ++ S +        K  KE +   E +G +C+ L     AG L V +LEAKNL+  +    S  +  VKI   ++G + K       K       PY+NE+F F  P   I    V V +           IG V +G   + T    HW  ML +PR P+A+WH L
Sbjct:  199 KTLNPTFNEHFTFKVPYSELGGKTLVMTVYDFDRFSKHDAIGDVRVQMNKVDFSQVTEEWRVLQKAEKEEQ---EKLGDICLSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKHTLN---PYYNESFSFEVPSEQIQKVQVVVTVLDYDKIGKNDAIGKVFMGLHSSGTEQR-HWADMLANPRRPIAQWHAL 406
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Sea Lamprey
Match: syt4 (synaptotagmin IV [Source:ZFIN;Acc:ZDB-GENE-030131-7297])

HSP 1 Score: 60.4622 bits (145), Expect = 3.425e-10
Identity = 58/219 (26.48%), Postives = 98/219 (44.75%), Query Frame = 1 
Query:  718 DPVFNEKFTFKILHP-ELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILN-SNGQAGLLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTIS-DCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSML---DSPRHPVAKWHVL 1356
            DPVF+E F F  L   ++  SEI F V  + +   + ++G++ +    +  ++   +++     +  G     G+G++ + L+ +   + L V IL+A+ L  K +   S     VK+ S   G++     K R + A  G    FNE+F      G  S + LV V    S     P  +G V LG+         HWQ +    D+   P+A+WH L
Sbjct:  198 DPVFDETFAFYGLSAVQMEGSEITFAVLSFGRLSREEVIGEVTVPLAGI--AAGPEVVAFCRHIVPRGMQKPAGVGELLVSLSFTQADSRLTVVILKARGLH-KRDTGSSLGAACVKV-SAFAGSERVLKRKTRVRRASSGAL--FNESFEVALGGGATSLELLVVVD---SADGAGPSPLGRVVLGAGAASPRARQHWQEVRAGGDAAGRPLARWHAL 407
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000226.1 (pep scaffold:Pmarinus_7.0:GL478944:1404:4221:1 gene:ENSPMAG00000000205.1 transcript:ENSPMAT00000000226.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.8398 bits (133), Expect = 8.532e-10
Identity = 49/149 (32.89%), Postives = 74/149 (49.66%), Query Frame = 1 
Query:  928 SEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYS-HIFVTVKIKSRKHG-NKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIW-ISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTN 1362
            S G G++ + L  +  A  L V +L+A++L   + +  S   +V V I S K    K KTH KK      C   P FNE+F+F  P   +SD  V + +    R  K  + IG ++LG       G  HW+ + ++PR  +AKWH L+ 
Sbjct:    2 SVGRGEILVSLCYHPAASRLTVVVLKARHLPKTDIVGLSVDPYVKVNIYSGKRRFAKKKTHVKK------CTLNPVFNESFVFELPEEGLSDLAVELTVVDFDRTTKDEV-IGRLALGP------GTEHWREVCENPRRQIAKWHPLSE 137
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Sea Lamprey
Match: syt4 (synaptotagmin IV [Source:ZFIN;Acc:ZDB-GENE-030131-7297])

HSP 1 Score: 57.3806 bits (137), Expect = 3.152e-9
Identity = 56/219 (25.57%), Postives = 96/219 (43.84%), Query Frame = 1 
Query:  718 DPVFNEKFTFKILHP-ELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILN-SNGQAGLLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTIS-DCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSML---DSPRHPVAKWHVL 1356
            DPVF+E F F  L   ++  SEI F V  + +   + ++G++ +    +  ++   +++     +  G     G+G++ + L+ +   + L V IL+A+ L  K +   S     VK+ S   G++     K R + A  G    FNE+F      G  S + LV V             +G V LG+         HWQ +    D+   P+A+WH L
Sbjct:  184 DPVFDETFAFYGLSAVQMEGSEITFAVLSFGRLSREEVIGEVTVPLAGI--AAGPEVVAFCRHIVPRGMQKPAGVGELLVSLSFTQADSRLTVVILKARGLH-KRDTGSSLGAACVKV-SAFAGSERVLKRKTRVRRASSGAL--FNESFEVALGGGATSLELLVVVHAGAGDEE-----LGRVVLGAGAASPRARQHWQEVRAGGDAAGRPLARWHAL 391
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006908.1 (pep scaffold:Pmarinus_7.0:GL476344:649897:653668:1 gene:ENSPMAG00000006246.1 transcript:ENSPMAT00000006908.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.9138 bits (128), Expect = 3.797e-9
Identity = 44/141 (31.21%), Postives = 60/141 (42.55%), Query Frame = 1 
Query:  937 MGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            +G +C  L      G L + ILEA NL+V +    S  +V  KI+  + G + K       K A     PYFNE F F  P   I    +   +           IG V +G      +G  HW  ML +PR P+ +WH L
Sbjct:   10 LGDICFSLRYIPSTGKLTIVILEATNLKVMDVSGASDPYV--KIQVMEGGIRLKKKKTTVKKKALN---PYFNEAFSFDIPFENIEKIQLVFSVMDYDSLSRNDAIGKVYVGCGA-AGAGHRHWSDMLANPRRPITQWHTL 144
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Sea Lamprey
Match: syt12 (synaptotagmin XII [Source:ZFIN;Acc:ZDB-GENE-081022-147])

HSP 1 Score: 51.6026 bits (122), Expect = 1.652e-7
Identity = 52/213 (24.41%), Postives = 87/213 (40.85%), Query Frame = 1 
Query:  727 FNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSK--DLKEGEDTSEGMGQVCIILNSNGQA-GLLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            F+E     +    ++D+ + F     D  G    +G   L   DL+       +  FS    L++    +E  G+V + L+    A  L V +++AK L   +       FV V +   + G K         +D      P +N+  +F  P  T+ D  + V +   R       IG+  +G + +  + A HWQ ML + R PV+ WH L
Sbjct:  103 FDEHLVMPLDAAAVDDTTLAFTALGLDSNGRQFSMGTAELRLGDLDLP-----VRPFSTWLYLQDSSQVAECCGEVLLSLSYLPTAERLTVVVVKAKGLEWPQGRESGAPFVKVYLL--QGGRKVSKKKTVTKRDER---NPVYNDAIIFSVPASTLQDISLRVTVADHREGMRAEDIGHAVIGPQSSGVALA-HWQQMLATLRRPVSMWHPL 304
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Nematostella
Match: EDO43704 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXY7])

HSP 1 Score: 86.6557 bits (213), Expect = 4.621e-19
Identity = 78/284 (27.46%), Postives = 138/284 (48.59%), Query Frame = 1 
Query:  529 ESFGKIYFAXXXXXXXXXXXXXXXXXXNLPTP-IDDCLDPYVVVQVXXXXXXXXXXXXXXYKHIDPVFNEKFTFKIL-HPELNDSEIFFKVFDYDKFGADSLLGQLALNFK--DLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCI-ILNSNGQAGLLVTILEAKNLRVKENMSYSHIFVTVKIKSR-KHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTN 1362
            E  GKI+F+L Y     +L +KV+K + LP        DP+V + +      + +    + K+++PV+NE FTF+   H +L    ++ +V DYD+F  +  +G++ +  +  DL P ++      F+KDL   +     +G + + ++       ++V +++A  L+  +    S  +V + I  + +  +K KT  K+RT+D      P +NE+F+F  P   I D      +           IG V LG      S   HW  M+++PR PVA+WH L +
Sbjct:    1 EQLGKIFFSLTYYSSDSVLTLKVLKAQGLPAKDFSGTSDPFVKIMLLPDKKHKLETRVKR-KNLNPVWNEVFTFEGFPHNKLMGKTLYMQVLDYDRFSRNDPIGEVEIPLENIDLGPVTLT-----FTKDLLPCKKDRVPLGDLLVSLMYQPTNNRIIVVVMKANKLKAMDLTGSSDPYVKMYIMHKDRRLDKKKTTIKRRTRD------PVWNESFIFDVPLDKIRDLTFVFNVMDYDRITQNELIGQVILGYRTT-GSSLRHWTEMMNNPRKPVAQWHRLQD 271
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Nematostella
Match: EDO31746 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX17])

HSP 1 Score: 86.6557 bits (213), Expect = 1.217e-18
Identity = 71/223 (31.84%), Postives = 111/223 (49.78%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFK-ILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIIN---MLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTN 1362
            K ++PVFNE+F FK I + E+ +  +  ++FD+D+F    L+G+  L   D++ +S IN   +L+  S     G   S+ +G +C  L     +G L +TI+EAK+L+  +   YS  +V  KI   + G   +   KK+T        PY+NETF F      I    + + +           IG   +G E++  +   HW  ML SPR  VA+WH L N
Sbjct:  142 KTLNPVFNEQFVFKNIPYSEITNRILLMELFDFDRFSRHDLIGEARLPLIDVDLASNINEWRVLTPPSGSGGAGHSKSD-LGDICFSLRYVPSSGKLQITIVEAKSLKSMDLTGYSDPYV--KIALVQEG---RKIKKKKTTVKKRTLNPYYNETFTFTVAFEKIEQTSLIISVLDYDRVGKSEMIGKCVVG-ELSSGADLRHWADMLASPRRSVAQWHTLHN 357
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Nematostella
Match: EDO41933 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S352])

HSP 1 Score: 84.3445 bits (207), Expect = 3.699e-18
Identity = 72/253 (28.46%), Postives = 120/253 (47.43%), Query Frame = 1 
Query:  640 DPYVVVQVX-XXXXXXXXXXXXXYKHIDPVFNEKFTF-KILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDL--KEGEDTSEGMGQVCIILNSNGQAGLL-VTILEAKNLRVKENMSYSHIFVTVKIK-SRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVLTNPNVKE 1377
            DPYV + +    S + + ++  KYK ++PVFNE  T+  I   E++   +  +VFD D  G +  +G+ ++N K LN     N    F + L  K  +     +G++ + L  N Q G+L VT++    L   +   YS  +V   +K   +  +K +T+ +K+T +      P FNE F++   H  ++   + V +W   + K    IG V L   +N    A+ HW  ML  P     +WH L N N  +
Sbjct:   55 DPYVKLHLLPGASKSNKLRSHTKYKTLNPVFNETLTYYGITEEEISSKTLRLQVFDEDTIGRNDFIGETSINLKLLNS----NPTQTFKRSLIPKALDSPHSPLGRIQLALKYNTQRGMLFVTVMRCSGLASMDANGYSDPYVKCYLKPDPQKKSKRRTNIRKKTLN------PEFNEEFVYDIAHHELAKKSLEVTVWDYDVGKSNDFIGGVIL--NINAEGSALKHWYDMLKGPNQLHTQWHTLENVNAHD 295
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Nematostella
Match: EDO50013 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF18])

HSP 1 Score: 81.6481 bits (200), Expect = 2.344e-17
Identity = 63/223 (28.25%), Postives = 103/223 (46.19%), Query Frame = 1 
Query:  706 YKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEG----EDTSEGMGQVCIILNSNGQAGLLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTN 1362
            YK+ +PVFNE F F +   EL +  + F + DYD +     LG++  +F D+N +   + +  + KD++       +     G+V + L     +G L  ++    L ++    YS     VK+     G + K   K +T   H    P +NE F+F  P   +SD  + V++  S   K    I    +G +   + G  HW  M+ SPR P+A+WH L N
Sbjct:   68 YKNSNPVFNETFEFDVAFSELPERTLQFCINDYDGYSRHQALGEVFHSF-DVNVNMQEDTVVIYEKDIRRDIFTFRENQVRKGEVLLSLCYLPTSGRLTFVVLKARLSMRLLFRYSLSDPFVKVSLMVSGRQIK---KTKTSVMHGTLRPVYNEAFVFDIPVERLSDVSLLVRMLHSDG-KRCQTIAKTVVGPDSQTSIGLHHWNCMMTSPRKPIAQWHPLLN 285
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Nematostella
Match: EDO31747 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX18])

HSP 1 Score: 70.0922 bits (170), Expect = 4.125e-13
Identity = 69/230 (30.00%), Postives = 103/230 (44.78%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAGLL-VTILEAKNLRVKENMSYSH-------IFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKP----HGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI--HWQSMLDSPRHPVAKWHVL 1356
            K  +P +NE F F I   +L D+ +   V + D++    ++GQ+ L   D+    + N +     ++ E   +  G+G + + L+    A  L V I++A+NL    N  +S        I   VK+     G K K   KK+T        P +NE+ LF  P    H  I    V+ K   SR   +   IG V +GS    +SG    HW  ML SPR P+A WH L
Sbjct:  143 KTTEPYYNETFQFSIEMEKLADAILSLLVMEVDRYSRHHVIGQIDLELGDV---VLANQMVAMEMEILEAYKSRLGLGDLLVSLSYMPTAERLSVVIMKARNL----NPPFSEWSSQPRDISPFVKVVLLFDGQKVK---KKKTSTRKQEKNPVYNESMLFDIPPHFLHRVILLISVADKPSDSRRSDI---IGRVVIGSP---SSGEALSHWNQMLVSPRRPIAAWHKL 356
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Medaka
Match: syt5a (synaptotagmin-1 [Source:NCBI gene;Acc:101166053])

HSP 1 Score: 108.227 bits (269), Expect = 2.167e-25
Identity = 76/218 (34.86%), Postives = 110/218 (50.46%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K++ PVFNE FTFKI + EL    +  +VFD+D+FG   ++G++ +    ++    I+      KDL  GE +  E +G +CI L     AG L V I+EAKNL+  +    S  FV V ++   +G + K   KK+T        PYFNE+F F  P   I    V + ++          IG   +G   +   G  HW  ML +PR PVA+WH L
Sbjct:  174 KNLCPVFNETFTFKIPYSELGGQTLVLQVFDFDRFGKHDVIGEIKIPMNSIDLGQPIHEW----KDLVGGEKEEQEKLGDICISLRYVPTAGKLTVNIMEAKNLKKMDVGGLSDPFVKVVLQH--NGKRLK---KKKTSVKQNTLNPYFNESFSFEIPFSQIQKVQVLITVYDYDKLGSNDPIGKCWIGYGASGV-GLRHWSDMLANPRRPVAQWHTL 381
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Medaka
Match: ENSORLT00000008980.2 (synaptotagmin-2-like [Source:NCBI gene;Acc:101157206])

HSP 1 Score: 100.523 bits (249), Expect = 1.082e-22
Identity = 74/220 (33.64%), Postives = 111/220 (50.45%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQ--LALNFKDLNPSSIINMLSEFSKDLKEG-EDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE F FK+ + EL    +   V+DYD+F    ++G+  LA+N  DL        + E+ +DL+   ++  E +G +CI L     AG L V ILEAKNL+  +    S  +V +++     G K     K   K       PY+NE+F F  P   +   LV+V ++          IG + +GS+     G  HW  ML +PR P+A+WHVL
Sbjct:  182 KTLNPVFNETFVFKVPYEELGGKTLCLSVYDYDRFSKHDVIGEVKLAMNTIDLG-----RPIEEW-RDLESADQEEPEKLGDICISLRYVPTAGKLTVCILEAKNLKKMDACGLSDPYVKIQL---LQGGKRLKKKKTTVKKNTLN--PYYNESFSFEIPLEQMQKILVAVTVFDYDKIGKNDAIGKIFVGSKATGL-GLKHWSDMLANPRRPIAQWHVL 389
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Medaka
Match: ENSORLT00000042397.1 (synaptotagmin-2-like [Source:NCBI gene;Acc:101157206])

HSP 1 Score: 100.523 bits (249), Expect = 1.462e-22
Identity = 74/220 (33.64%), Postives = 111/220 (50.45%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQ--LALNFKDLNPSSIINMLSEFSKDLKEG-EDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE F FK+ + EL    +   V+DYD+F    ++G+  LA+N  DL        + E+ +DL+   ++  E +G +CI L     AG L V ILEAKNL+  +    S  +V +++     G K     K   K       PY+NE+F F  P   +   LV+V ++          IG + +GS+     G  HW  ML +PR P+A+WHVL
Sbjct:  206 KTLNPVFNETFVFKVPYEELGGKTLCLSVYDYDRFSKHDVIGEVKLAMNTIDLG-----RPIEEW-RDLESADQEEPEKLGDICISLRYVPTAGKLTVCILEAKNLKKMDACGLSDPYVKIQL---LQGGKRLKKKKTTVKKNTLN--PYYNESFSFEIPLEQMQKILVAVTVFDYDKIGKNDAIGKIFVGSKATGL-GLKHWSDMLANPRRPIAQWHVL 413
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Medaka
Match: syt1b (synaptotagmin-1-like [Source:NCBI gene;Acc:101162836])

HSP 1 Score: 93.5893 bits (231), Expect = 2.432e-20
Identity = 69/217 (31.80%), Postives = 104/217 (47.93%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVL 1356
            K ++P FNE FTFK+ + E+    +   V+D+D+F     +G + +  + ++ S  +    +  K  KE    SE +G +C+ L     AG L V ILEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    V+V +           IG V LG   + T    HW  ML +PR P+A+WH L
Sbjct:  186 KTLEPTFNETFTFKVPYTEMGGRTLVMTVYDFDRFSKHDAIGAVKIPMRGVDFSQSMQEWRDLQKAEKE---ESERLGDICLSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPCEQIEKVQVAVTVLDYDKIGKNDAIGKVLLGGNSSGTEQR-HWSDMLANPRRPIAQWHSL 393
[Close]
BLAST of Synaptotagmin-2 vs. Ensembl Medaka
Match: syt1a (synaptotagmin 1 [Source:NCBI gene;Acc:101166921])

HSP 1 Score: 91.2781 bits (225), Expect = 1.643e-19
Identity = 68/219 (31.05%), Postives = 109/219 (49.77%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGE-DTSEGMGQVCIILNSNGQAG-LLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVL 1356
            K ++PVFNE+FTFK+ + EL    +   V+D+D+F     +G + +    ++ S +    +E  +DL+  E +  E +G +C  L     AG L V +LEAKNL+  +    S  +  VKI   ++G + K       K+      PY+NE+F F  P   I    + + +           IG V +G  +N +   + HW  ML +PR P+A+WHVL
Sbjct:  201 KTLNPVFNEQFTFKVPYVELGGKTLVMTVYDFDRFSKHDAIGDIKVPMNKVDFSHV----TEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVVLEAKNLKKMDVGGLSDPY--VKIHLMQNGKRLKKKKTTIKKNTLN---PYYNESFSFEVPFEQIQKVQIVITVLDYDKIGKNDAIGKVFVG--LNSSGTELRHWSDMLANPRRPIAQWHVL 408
[Close]
BLAST of Synaptotagmin-2 vs. Planmine SMEST
Match: SMESG000011583.1 (SMESG000011583.1)

HSP 1 Score: 686.026 bits (1769), Expect = 0.000e+0
Identity = 381/381 (100.00%), Postives = 381/381 (100.00%), Query Frame = 1 
Query:  235 MSATLSTMSTLKFTRPTNVTSNLYKDIIKYLDLPEPLIVAIFAAAGLLIFVIFILFXXXXXXXXXXXQTADKDKYKRRKLETKEIDKIFRDELNLGFNESFGKIYFAXXXXXXXXXXXXXXXXXXNLPTPIDDCLDPYVVVQVXXXXXXXXXXXXXXYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAGLLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPNVKE 1377
            MSATLSTMSTLKFTRPTNVTSNLYKDIIKYLDLPEPLIVAIFAAAGLLIFVIFILFCSRCCCRKCCKQTADKDKYKRRKLETKEIDKIFRDELNLGFNESFGKIYFALKYLLVKELLIVKVIKVENLPTPIDDCLDPYVVVQVKSKSLTEEKKTKIKYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAGLLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPNVKE
Sbjct:    1 MSATLSTMSTLKFTRPTNVTSNLYKDIIKYLDLPEPLIVAIFAAAGLLIFVIFILFCSRCCCRKCCKQTADKDKYKRRKLETKEIDKIFRDELNLGFNESFGKIYFALKYLLVKELLIVKVIKVENLPTPIDDCLDPYVVVQVKSKSLTEEKKTKIKYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAGLLVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPNVKE 381
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BLAST of Synaptotagmin-2 vs. Planmine SMEST
Match: SMESG000041533.1 (SMESG000041533.1)

HSP 1 Score: 89.3521 bits (220), Expect = 2.892e-19
Identity = 101/341 (29.62%), Postives = 164/341 (48.09%), Query Frame = 1 
Query:  367 AGLLIFVIFILFXXXXXXXXXXXQTADKDKYKRRKLETKEIDKIFRDELNLGFNESFGKIYFAXXXXXXXXXXXXXXXXXXNLPTPIDDCLDPYVVVQVXXXX-XXXXXXXXXXYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFG-ADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAGLL-VTILEAKNLRVKENMSYSHIFVTVKIKSRKH-GNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAIHWQSMLDSPRHPVAKWHVLTNPNVKE 1377
            AG+ +F++F+L      C      T    K   +K  TK  D  F D++        G I FA+ YL  K +L+V V++V  L +P +  +D YV V+++ +S   + +KTKI+++  +P F++KF F+IL  EL ++ +  +VFD+D  G ADS+LG +      +      N+  E    L    ++ EG G++CI+L       LL VT+LE K L  K       I+V+V+   +        T +K  T+D      PYF+ETF +           +  K++      +  C+G + +GS     S   HW  M+  PR   + WH L+    K+
Sbjct:   31 AGICLFILFLL----GICLLKRIHTIRNSKTALKKRFTKITDMHFEDDVGEYKPSKLGDISFAIDYLFGKNILVVNVMQVFGLTSPSNVEIDSYVKVRIEPESWNIKPRKTKIQHQTNNPTFSKKFQFRILKSELENAVVILEVFDHDIAGAADSMLGIMRFPISLMTHEEFQNLPCEKKLPLDPPTESHEGNGEICIVLRHFPIEHLLKVTVLEIKRLHFKSKTKILPIYVSVEFYFKNELLETKYTTTKYNTRD------PYFSETFEYHLKPVKAPYVYLLFKVFQKPTIGLKKCLGKLEIGSNSPTLSAQNHWMDMVAYPRVAKSCWHALSKDESKD 361
[Close]
BLAST of Synaptotagmin-2 vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1)

HSP 1 Score: 87.4261 bits (215), Expect = 2.027e-18
Identity = 67/220 (30.45%), Postives = 101/220 (45.91%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAGLL-VTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVLTN 1362
            K ++PVFNE F FKI + E+    + F VFD+D+F     +GQ+ +    ++   +I    E      + E  +  +G +C  L     +G L + ILEAKNL+  +    S  +  VK+    +G + K       K       PY+NE+F F  P   I    + V +           IG V LG   N T   + HW  ML +PR P+A+WH L +
Sbjct:  188 KILNPVFNETFVFKIPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEWKELGPPDSDNEKENR-LGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPY--VKLSLMLNGKRVKKKKTTIKKYTLN---PYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRVVLGC--NATGAELRHWSDMLANPRRPIAQWHTLQD 399
[Close]
BLAST of Synaptotagmin-2 vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1)

HSP 1 Score: 87.4261 bits (215), Expect = 2.206e-18
Identity = 67/220 (30.45%), Postives = 101/220 (45.91%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAGLL-VTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVLTN 1362
            K ++PVFNE F FKI + E+    + F VFD+D+F     +GQ+ +    ++   +I    E      + E  +  +G +C  L     +G L + ILEAKNL+  +    S  +  VK+    +G + K       K       PY+NE+F F  P   I    + V +           IG V LG   N T   + HW  ML +PR P+A+WH L +
Sbjct:  192 KILNPVFNETFVFKIPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEWKELGPPDSDNEKENR-LGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPY--VKLSLMLNGKRVKKKKTTIKKYTLN---PYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRVVLGC--NATGAELRHWSDMLANPRRPIAQWHTLQD 403
[Close]
BLAST of Synaptotagmin-2 vs. Planmine SMEST
Match: SMESG000055143.1 (SMESG000055143.1)

HSP 1 Score: 87.4261 bits (215), Expect = 2.354e-18
Identity = 67/220 (30.45%), Postives = 101/220 (45.91%), Query Frame = 1 
Query:  709 KHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLGQLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAGLL-VTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCGPFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNMTSGAI-HWQSMLDSPRHPVAKWHVLTN 1362
            K ++PVFNE F FKI + E+    + F VFD+D+F     +GQ+ +    ++   +I    E      + E  +  +G +C  L     +G L + ILEAKNL+  +    S  +  VK+    +G + K       K       PY+NE+F F  P   I    + V +           IG V LG   N T   + HW  ML +PR P+A+WH L +
Sbjct:  204 KILNPVFNETFVFKIPYSEVGSKTLVFNVFDFDRFSKHDQIGQIQIPLGSVDLCKVIEEWKELGPPDSDNEKENR-LGDICFSLRYVPTSGKLNIVILEAKNLKKMDVGGLSDPY--VKLSLMLNGKRVKKKKTTIKKYTLN---PYYNESFSFEVPFEQIQKVNLIVTVVDYDRIGTSEPIGRVVLGC--NATGAELRHWSDMLANPRRPIAQWHTLQD 415
The following BLAST results are available for this feature:
BLAST of Synaptotagmin-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SYT21.019e-2032.11synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:11510... [more]
SYT21.019e-2032.11synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:11510... [more]
SYT11.135e-2031.14synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509... [more]
SYT11.135e-2031.14synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509... [more]
SYT11.135e-2031.14synaptotagmin 1 [Source:HGNC Symbol;Acc:HGNC:11509... [more]
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BLAST of Synaptotagmin-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snt-11.597e-2030.91Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:... [more]
snt-13.957e-1931.84Synaptotagmin-1 [Source:UniProtKB/Swiss-Prot;Acc:... [more]
snt-21.663e-1728.95Synaptotagmin 2 [Source:UniProtKB/Swiss-Prot;Acc:... [more]
snt-65.951e-1527.80SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:A0A0S4... [more]
snt-31.469e-1428.77SyNapTotagmin [Source:UniProtKB/TrEMBL;Acc:Q965S5... [more]
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BLAST of Synaptotagmin-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Syt11.692e-2234.06gene:FBgn0004242 transcript:FBtr0077726[more]
Syt11.749e-2234.06gene:FBgn0004242 transcript:FBtr0077728[more]
Syt11.749e-2234.06gene:FBgn0004242 transcript:FBtr0345331[more]
Syt11.749e-2234.06gene:FBgn0004242 transcript:FBtr0077727[more]
Syt12.647e-2133.04gene:FBgn0004242 transcript:FBtr0332218[more]
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BLAST of Synaptotagmin-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syt5a5.124e-2334.09synaptotagmin Va [Source:ZFIN;Acc:ZDB-GENE-040718-... [more]
syt1a2.827e-2031.96synaptotagmin Ia [Source:ZFIN;Acc:ZDB-GENE-040718-... [more]
syt1a2.827e-2031.96synaptotagmin Ia [Source:ZFIN;Acc:ZDB-GENE-040718-... [more]
syt5b1.353e-1834.25synaptotagmin Vb [Source:ZFIN;Acc:ZDB-GENE-050522-... [more]
syt5b1.382e-1834.25synaptotagmin Vb [Source:ZFIN;Acc:ZDB-GENE-050522-... [more]
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BLAST of Synaptotagmin-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syt87.158e-2229.75synaptotagmin 8 [Source:NCBI gene;Acc:100037878][more]
e2f41.293e-2031.44E2F transcription factor 4 [Source:Xenbase;Acc:XB-... [more]
luzp24.339e-2031.65leucine zipper protein 2 [Source:Xenbase;Acc:XB-GE... [more]
SYT55.448e-1930.59synaptotagmin 5 [Source:NCBI gene;Acc:100493612][more]
SYT56.081e-1930.59synaptotagmin 5 [Source:NCBI gene;Acc:100493612][more]
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BLAST of Synaptotagmin-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Syt114.071e-2131.67synaptotagmin XI [Source:MGI Symbol;Acc:MGI:185954... [more]
Syt16.423e-2131.14synaptotagmin I [Source:MGI Symbol;Acc:MGI:99667][more]
Syt16.423e-2131.14synaptotagmin I [Source:MGI Symbol;Acc:MGI:99667][more]
Syt27.040e-2132.11synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666][more]
Syt27.040e-2132.11synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666][more]
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BLAST of Synaptotagmin-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5R4J5|SYT1_PONAB6.937e-2332.02Synaptotagmin-1 OS=Pongo abelii OX=9601 GN=SYT1 PE... [more]
sp|P21521|SY65_DROME1.696e-2134.06Synaptotagmin 1 OS=Drosophila melanogaster OX=7227... [more]
sp|P29101|SYT2_RAT4.053e-2032.11Synaptotagmin-2 OS=Rattus norvegicus OX=10116 GN=S... [more]
sp|P46096|SYT1_MOUSE4.493e-2031.14Synaptotagmin-1 OS=Mus musculus OX=10090 GN=Syt1 P... [more]
sp|P47191|SYT1_CHICK4.778e-2031.74Synaptotagmin-1 OS=Gallus gallus OX=9031 GN=SYT1 P... [more]
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BLAST of Synaptotagmin-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A093ESP23.105e-2532.11Synaptotagmin-1 (Fragment) OS=Gavia stellata OX=37... [more]
U3KB146.224e-2532.11Synaptotagmin 8 OS=Ficedula albicollis OX=59894 GN... [more]
A0A218USQ38.366e-2531.71Synaptotagmin-1 OS=Lonchura striata domestica OX=2... [more]
A0A3M0JZ481.906e-2431.30Uncharacterized protein OS=Hirundo rustica rustica... [more]
A0A3P8XSZ32.678e-2434.53Synaptotagmin Va OS=Esox lucius OX=8010 PE=4 SV=1[more]
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BLAST of Synaptotagmin-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syt5a3.477e-2333.49synaptotagmin-2-like [Source:NCBI gene;Acc:1030278... [more]
syt5a3.912e-2333.49synaptotagmin-2-like [Source:NCBI gene;Acc:1030278... [more]
ENSAMXT00000017640.28.023e-2331.95synaptotagmin-1-like [Source:NCBI gene;Acc:1030358... [more]
syt5b3.400e-2032.89synaptotagmin-1-like [Source:NCBI gene;Acc:1030298... [more]
syt1b4.872e-1930.88synaptotagmin Ib [Source:ZFIN;Acc:ZDB-GENE-060503-... [more]
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BLAST of Synaptotagmin-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syt43.425e-1026.48synaptotagmin IV [Source:ZFIN;Acc:ZDB-GENE-030131-... [more]
ENSPMAT00000000226.18.532e-1032.89pep scaffold:Pmarinus_7.0:GL478944:1404:4221:1 gen... [more]
syt43.152e-925.57synaptotagmin IV [Source:ZFIN;Acc:ZDB-GENE-030131-... [more]
ENSPMAT00000006908.13.797e-931.21pep scaffold:Pmarinus_7.0:GL476344:649897:653668:1... [more]
syt121.652e-724.41synaptotagmin XII [Source:ZFIN;Acc:ZDB-GENE-081022... [more]
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BLAST of Synaptotagmin-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Synaptotagmin-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO437044.621e-1927.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO317461.217e-1831.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO419333.699e-1828.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO500132.344e-1728.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO317474.125e-1330.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Synaptotagmin-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
syt5a2.167e-2534.86synaptotagmin-1 [Source:NCBI gene;Acc:101166053][more]
ENSORLT00000008980.21.082e-2233.64synaptotagmin-2-like [Source:NCBI gene;Acc:1011572... [more]
ENSORLT00000042397.11.462e-2233.64synaptotagmin-2-like [Source:NCBI gene;Acc:1011572... [more]
syt1b2.432e-2031.80synaptotagmin-1-like [Source:NCBI gene;Acc:1011628... [more]
syt1a1.643e-1931.05synaptotagmin 1 [Source:NCBI gene;Acc:101166921][more]
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BLAST of Synaptotagmin-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000011583.10.000e+0100.00SMESG000011583.1[more]
SMESG000041533.12.892e-1929.62SMESG000041533.1[more]
SMESG000055143.12.027e-1830.45SMESG000055143.1[more]
SMESG000055143.12.206e-1830.45SMESG000055143.1[more]
SMESG000055143.12.354e-1830.45SMESG000055143.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022362 ID=SMED30022362|Name=Synaptotagmin-2|organism=Schmidtea mediterranea sexual|type=transcript|length=1443bp
CTCTTCCGATCTCAAACATTTCAGTCGCAAAGCAGGTCGCCACGAAATAC
ATAAATCCGAACTCAACTGCTATTTGCATTAAGCATTTCAATGGCCTTCA
CGAACATACCAAGCACACACCGACCTTTTGCATAGCAAAATAATTTATTA
TCATTAAAACAACCTTTGTGACTCTATTTTATCGATTTGAACGAAATTCA
CCACGATGGCACCATAAACAATCAGATCTCACAAATGTCTGCGACTCTAA
GCACAATGTCAACACTGAAGTTCACAAGGCCAACAAATGTAACCTCAAAC
CTCTACAAAGACATAATCAAATATCTTGATCTCCCGGAACCGTTGATTGT
AGCAATCTTTGCCGCTGCTGGTTTGTTAATATTCGTTATTTTCATATTGT
TTTGTTCGAGATGCTGCTGCAGAAAATGCTGCAAGCAAACTGCCGATAAA
GACAAATACAAAAGACGGAAGCTAGAAACAAAAGAAATTGACAAAATTTT
CAGAGACGAGTTGAATCTTGGATTTAATGAGAGTTTTGGAAAGATATATT
TTGCGCTCAAATATCTCCTCGTAAAAGAATTGTTAATTGTAAAGGTTATT
AAGGTGGAAAACCTACCGACACCAATTGACGACTGTCTTGATCCATACGT
TGTCGTACAAGTGAAATCAAAAAGTTTGACTGAGGAAAAGAAAACCAAAA
TTAAATACAAACATATAGATCCGGTATTCAATGAAAAGTTTACTTTCAAA
ATTCTCCATCCAGAACTTAATGATTCGGAAATTTTTTTTAAGGTTTTTGA
CTATGATAAATTTGGAGCCGACTCATTGCTAGGTCAACTTGCACTAAATT
TTAAAGACCTCAATCCCAGTAGCATCATAAACATGTTGTCAGAGTTTTCC
AAAGATTTAAAAGAAGGTGAAGATACATCGGAAGGCATGGGACAGGTATG
CATAATTCTGAATTCAAATGGACAGGCAGGATTACTAGTCACTATACTAG
AAGCTAAAAATCTTCGAGTTAAAGAAAACATGAGTTATTCTCACATTTTT
GTCACAGTTAAAATCAAGTCTCGGAAACACGGGAACAAATTTAAAACTCA
CTCGAAAAAAAGAACCAAAGACGCTCATTGTGGACCTTTTCCGTATTTCA
ATGAAACATTTCTTTTCCCGAAACCTCATGGAACGATATCAGACTGTTTA
GTATCAGTTAAAATTTGGATCAGTAGAATGTTTAAAATGCCAATCTGCAT
CGGGTACGTCTCATTAGGTTCTGAAATGAATATGACTTCCGGCGCCATTC
ATTGGCAAAGCATGCTTGACAGTCCCCGACACCCGGTTGCAAAATGGCAT
GTCCTAACCAATCCTAATGTGAAAGAATAAAGATTTAATATTTAGTCCTT
CAACATATCTTTTTAATAATTAAAATAATAATTATTTGTCGGT
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protein sequence of SMED30022362-orf-1

>SMED30022362-orf-1 ID=SMED30022362-orf-1|Name=SMED30022362-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=382bp
MSATLSTMSTLKFTRPTNVTSNLYKDIIKYLDLPEPLIVAIFAAAGLLIF
VIFILFCSRCCCRKCCKQTADKDKYKRRKLETKEIDKIFRDELNLGFNES
FGKIYFALKYLLVKELLIVKVIKVENLPTPIDDCLDPYVVVQVKSKSLTE
EKKTKIKYKHIDPVFNEKFTFKILHPELNDSEIFFKVFDYDKFGADSLLG
QLALNFKDLNPSSIINMLSEFSKDLKEGEDTSEGMGQVCIILNSNGQAGL
LVTILEAKNLRVKENMSYSHIFVTVKIKSRKHGNKFKTHSKKRTKDAHCG
PFPYFNETFLFPKPHGTISDCLVSVKIWISRMFKMPICIGYVSLGSEMNM
TSGAIHWQSMLDSPRHPVAKWHVLTNPNVKE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000043dorsal ventral margin of the whole animal
PLANA:0000420parapharyngeal region
PLANA:0002032epidermal cell
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR035892C2_domain_sf
IPR000008C2_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: biological process
TermDefinition
GO:0006887exocytosis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000008C2 domainSMARTSM00239C2_3ccoord: 249..369
e-value: 9.3E-9
score: 45.1
coord: 116..218
e-value: 4.9E-16
score: 69.3
IPR000008C2 domainPFAMPF00168C2coord: 250..348
e-value: 2.1E-7
score: 31.1
coord: 117..214
e-value: 1.1E-17
score: 64.1
IPR000008C2 domainPROSITEPS50004C2coord: 117..203
score: 15.577
IPR035892C2 domain superfamilyGENE3DG3DSA:2.60.40.150coord: 93..221
e-value: 1.8E-27
score: 97.7
IPR035892C2 domain superfamilyGENE3DG3DSA:2.60.40.150coord: 222..376
e-value: 1.0E-22
score: 82.3
NoneNo IPR availablePANTHERPTHR10024SYNAPTOTAGMINcoord: 47..376
NoneNo IPR availablePANTHERPTHR10024:SF227SYNAPTOTAGMIN 1coord: 47..376
NoneNo IPR availableSUPERFAMILYSSF49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 249..375
NoneNo IPR availableSUPERFAMILYSSF49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 96..216
NoneNo IPR availableTMHMMTMhelixcoord: 36..58