FERM domain containing-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30022344 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 16
Homology
BLAST of FERM domain containing-1 vs. Ensembl Human
Match: MSN (moesin [Source:HGNC Symbol;Acc:HGNC:7373]) HSP 1 Score: 422.165 bits (1084), Expect = 1.676e-140 Identity = 184/302 (60.93%), Postives = 249/302 (82.45%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M K ISV+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL ++D+KGF TWLK N+K+TAQDV K+ PL FKF K+YPE+V EL+Q++TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGDF +E+ + ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF+IKNKKGSEL LGVDALGL+IY+Q+++LTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEV--HKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 77.411 bits (189), Expect = 3.174e-14 Identity = 40/76 (52.63%), Postives = 49/76 (64.47%), Query Frame = 3
Query: 1515 DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
DR EE R T N +Q LK+L +L R +K D IH EN RLG DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 502 DRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM 577
BLAST of FERM domain containing-1 vs. Ensembl Human
Match: RDX (radixin [Source:HGNC Symbol;Acc:HGNC:9944]) HSP 1 Score: 420.239 bits (1079), Expect = 9.147e-140 Identity = 201/340 (59.12%), Postives = 272/340 (80.00%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLA 1079
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E I P ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKE-IHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIA 333 HSP 2 Score: 69.3218 bits (168), Expect = 1.131e-11 Identity = 36/78 (46.15%), Postives = 51/78 (65.38%), Query Frame = 3
Query: 1509 VDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
++ R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 506 MNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 583
BLAST of FERM domain containing-1 vs. Ensembl Human
Match: RDX (radixin [Source:HGNC Symbol;Acc:HGNC:9944]) HSP 1 Score: 418.698 bits (1075), Expect = 9.620e-140 Identity = 227/437 (51.95%), Postives = 316/437 (72.31%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLAD-------------MELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQIS 1331
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E I P ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A+ ME RLK ++ E T + +E E + R+ EL ++ R K E E RL + +RA E AK+ + +K EQ+ +++
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKE-IHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIAEKEKERIEREKEELME-RLK---QIEEQTIKAQKELEEQTRKALELDQERKRAKEEAE----RLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELA 422
BLAST of FERM domain containing-1 vs. Ensembl Human
Match: RDX (radixin [Source:HGNC Symbol;Acc:HGNC:9944]) HSP 1 Score: 420.239 bits (1079), Expect = 1.238e-139 Identity = 201/340 (59.12%), Postives = 272/340 (80.00%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLA 1079
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E I P ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKE-IHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIA 333 HSP 2 Score: 69.3218 bits (168), Expect = 1.246e-11 Identity = 36/78 (46.15%), Postives = 51/78 (65.38%), Query Frame = 3
Query: 1509 VDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
++ R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 506 MNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 583
BLAST of FERM domain containing-1 vs. Ensembl Human
Match: RDX (radixin [Source:HGNC Symbol;Acc:HGNC:9944]) HSP 1 Score: 419.468 bits (1077), Expect = 3.916e-139 Identity = 201/340 (59.12%), Postives = 272/340 (80.00%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLA 1079
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E I P ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKE-IHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIA 333 HSP 2 Score: 69.3218 bits (168), Expect = 1.106e-11 Identity = 36/78 (46.15%), Postives = 51/78 (65.38%), Query Frame = 3
Query: 1509 VDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
++ R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 506 MNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 583
BLAST of FERM domain containing-1 vs. Ensembl Celegans
Match: erm-1 (ERM-1B; Ezrin/Radixin/Moesin [Source:UniProtKB/TrEMBL;Acc:G5EBK3]) HSP 1 Score: 435.647 bits (1119), Expect = 2.057e-146 Identity = 247/565 (43.72%), Postives = 370/565 (65.49%), Query Frame = 3
Query: 66 KPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKNIEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVTLGSMEFVDD------RREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
K I+V++++++SELEF++ ++TTG++LF+QVVKT+ LRE W+FGL + D+KGFPTWLK N+K+ +QDV K L FKF K+YPE+V E++Q+VT RLFYLQV++ IL IYCPPE+SVLLASYA Q KYGD+ E + D LLP+RV+ Q +++ +W I+ + +H+ RE+A++EYLK+AQDLEM+GVNYF I+NKKG++L LGVDALGL+IY + ++L+P +GFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMK QA E+R K ++K+TRE A+EE E++ D E R+ + E E + +L E I LE L+Q K+ LE+ L E L+ KA +D +R L + + + ++ EVE + ++ ++ +++ S A +++ +D G+ E +D + E R T NI+++N+L L ++L+ + N + D +H EN++ G DK+KTLRQIR GNTK+R+D++E +
Sbjct: 4 KAINVRVTSMDSELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYTDNKGFPTWLKLNKKVLSQDVKKDPTLVFKFRAKFYPEDVAEEIIQDVTMRLFYLQVKDGILSDEIYCPPETSVLLASYAMQAKYGDYVPET--HVAGCLTADRLLPQRVLGQFKLNSEEWERRIMTWWADHRATTREQAMLEYLKIAQDLEMYGVNYFEIRNKKGTDLYLGVDALGLNIYDKADRLSPKVGFPWSEIRNISFNDKKFVIKPIDKKAHDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKQQAREDRALKIAEQEKLTREMSAREEAEQRQRDAEKRMAQMQEDMERARLELAEAHNTIHSLEAQLKQLQLAKQALEQKEYELRELTAQLQSEKAMSDGERRHLRDQVDAREREVFSMREEVERQT---TVTRQLQTQIHSQQHTQHYSNSHHVSNGHAHDETATDDEDNGATELTNDADQNVPQHELERVTAAEKNIQIKNKLDMLTRELDSVKDQNAVTDYDVLHMENKKAGRDKYKTLRQIRGGNTKRRIDQYENM 563
BLAST of FERM domain containing-1 vs. Ensembl Celegans
Match: erm-1 (ERM-1B; Ezrin/Radixin/Moesin [Source:UniProtKB/TrEMBL;Acc:G5EBK3]) HSP 1 Score: 434.106 bits (1115), Expect = 8.472e-146 Identity = 246/563 (43.69%), Postives = 369/563 (65.54%), Query Frame = 3
Query: 72 ISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKNIEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVTLGSMEFVDD------RREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
I+V++++++SELEF++ ++TTG++LF+QVVKT+ LRE W+FGL + D+KGFPTWLK N+K+ +QDV K L FKF K+YPE+V E++Q+VT RLFYLQV++ IL IYCPPE+SVLLASYA Q KYGD+ E + D LLP+RV+ Q +++ +W I+ + +H+ RE+A++EYLK+AQDLEM+GVNYF I+NKKG++L LGVDALGL+IY + ++L+P +GFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMK QA E+R K ++K+TRE A+EE E++ D E R+ + E E + +L E I LE L+Q K+ LE+ L E L+ KA +D +R L + + + ++ EVE + ++ ++ +++ S A +++ +D G+ E +D + E R T NI+++N+L L ++L+ + N + D +H EN++ G DK+KTLRQIR GNTK+R+D++E +
Sbjct: 7 INVRVTSMDSELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYTDNKGFPTWLKLNKKVLSQDVKKDPTLVFKFRAKFYPEDVAEEIIQDVTMRLFYLQVKDGILSDEIYCPPETSVLLASYAMQAKYGDYVPET--HVAGCLTADRLLPQRVLGQFKLNSEEWERRIMTWWADHRATTREQAMLEYLKIAQDLEMYGVNYFEIRNKKGTDLYLGVDALGLNIYDKADRLSPKVGFPWSEIRNISFNDKKFVIKPIDKKAHDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKQQAREDRALKIAEQEKLTREMSAREEAEQRQRDAEKRMAQMQEDMERARLELAEAHNTIHSLEAQLKQLQLAKQALEQKEYELRELTAQLQSEKAMSDGERRHLRDQVDAREREVFSMREEVERQT---TVTRQLQTQIHSQQHTQHYSNSHHVSNGHAHDETATDDEDNGATELTNDADQNVPQHELERVTAAEKNIQIKNKLDMLTRELDSVKDQNAVTDYDVLHMENKKAGRDKYKTLRQIRGGNTKRRIDQYENM 564
BLAST of FERM domain containing-1 vs. Ensembl Celegans
Match: nfm-1 (NeuroFibroMatosis homolog [Source:UniProtKB/TrEMBL;Acc:Q5LK46]) HSP 1 Score: 276.559 bits (706), Expect = 3.348e-84 Identity = 147/350 (42.00%), Postives = 232/350 (66.29%), Query Frame = 3
Query: 63 SKPISVKISTVESELEFSVAANT-TGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYP---LQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLK 1100
+KPI K+ST++++LE V T TG LFE V + + LRETW+FGL F + K P WL+ ++ I QD+ K F F VK+YPE+VE E++ + T+ LF+LQ+R IL ++YC PE+SVLLAS+A Q +GD EE+ I+ D LP+ VI+Q+++S W + I + + + REEA +EYL++AQDLEM+G+ Y+ I N K ++L LG+ A GL IYK N++TP F WSEIKN+ + N+KF +K+ DK S F + + I+ +IL + +G H+LYL+RR+PDT+E+QQM++QA+E+++ + + K+ ER ++++E++ +M+ +++
Sbjct: 11 TKPIYAKVSTMDADLEKIVIEKTWTGRHLFEAVCRIIGLRETWYFGLQFTNKKNIPCWLQNDKTICGQDIQKDTSDGTFNFLFLVKFYPEDVEPEIILDATRHLFFLQIREAILSMNLYCSPEASVLLASFAVQAMHGDCTEEV-----GPIDLDKHLPKSVIDQYDMSADMWRDRIKRWWSRNAGQSREEAELEYLRVAQDLEMYGILYYPICNNKETDLHLGISAQGLGIYKGVNRITPRPFFSWSEIKNIQFKNRKFHMKTVDK--STISFRSRETSIDSSILDLCIGTHNLYLRRRQPDTLEVQQMRSQAKEDKQRRAAEQAKVALERKERQQMEKEYKEMKQKVE 353
BLAST of FERM domain containing-1 vs. Ensembl Celegans
Match: nfm-1 (NeuroFibroMatosis homolog [Source:UniProtKB/TrEMBL;Acc:Q5LK46]) HSP 1 Score: 276.944 bits (707), Expect = 3.392e-84 Identity = 147/350 (42.00%), Postives = 232/350 (66.29%), Query Frame = 3
Query: 63 SKPISVKISTVESELEFSVAANT-TGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYP---LQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLK 1100
+KPI K+ST++++LE V T TG LFE V + + LRETW+FGL F + K P WL+ ++ I QD+ K F F VK+YPE+VE E++ + T+ LF+LQ+R IL ++YC PE+SVLLAS+A Q +GD EE+ I+ D LP+ VI+Q+++S W + I + + + REEA +EYL++AQDLEM+G+ Y+ I N K ++L LG+ A GL IYK N++TP F WSEIKN+ + N+KF +K+ DK S F + + I+ +IL + +G H+LYL+RR+PDT+E+QQM++QA+E+++ + + K+ ER ++++E++ +M+ +++
Sbjct: 11 TKPIYAKVSTMDADLEKIVIEKTWTGRHLFEAVCRIIGLRETWYFGLQFTNKKNIPCWLQNDKTICGQDIQKDTSDGTFNFLFLVKFYPEDVEPEIILDATRHLFFLQIREAILSMNLYCSPEASVLLASFAVQAMHGDCTEEV-----GPIDLDKHLPKSVIDQYDMSADMWRDRIKRWWSRNAGQSREEAELEYLRVAQDLEMYGILYYPICNNKETDLHLGISAQGLGIYKGVNRITPRPFFSWSEIKNIQFKNRKFHMKTVDK--STISFRSRETSIDSSILDLCIGTHNLYLRRRQPDTLEVQQMRSQAKEDKQRRAAEQAKVALERKERQQMEKEYKEMKQKVE 353
BLAST of FERM domain containing-1 vs. Ensembl Celegans
Match: nfm-1 (NeuroFibroMatosis homolog [Source:UniProtKB/TrEMBL;Acc:Q5LK46]) HSP 1 Score: 276.559 bits (706), Expect = 1.549e-83 Identity = 147/350 (42.00%), Postives = 232/350 (66.29%), Query Frame = 3
Query: 63 SKPISVKISTVESELEFSVAANT-TGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYP---LQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLK 1100
+KPI K+ST++++LE V T TG LFE V + + LRETW+FGL F + K P WL+ ++ I QD+ K F F VK+YPE+VE E++ + T+ LF+LQ+R IL ++YC PE+SVLLAS+A Q +GD EE+ I+ D LP+ VI+Q+++S W + I + + + REEA +EYL++AQDLEM+G+ Y+ I N K ++L LG+ A GL IYK N++TP F WSEIKN+ + N+KF +K+ DK S F + + I+ +IL + +G H+LYL+RR+PDT+E+QQM++QA+E+++ + + K+ ER ++++E++ +M+ +++
Sbjct: 11 TKPIYAKVSTMDADLEKIVIEKTWTGRHLFEAVCRIIGLRETWYFGLQFTNKKNIPCWLQNDKTICGQDIQKDTSDGTFNFLFLVKFYPEDVEPEIILDATRHLFFLQIREAILSMNLYCSPEASVLLASFAVQAMHGDCTEEV-----GPIDLDKHLPKSVIDQYDMSADMWRDRIKRWWSRNAGQSREEAELEYLRVAQDLEMYGILYYPICNNKETDLHLGISAQGLGIYKGVNRITPRPFFSWSEIKNIQFKNRKFHMKTVDK--STISFRSRETSIDSSILDLCIGTHNLYLRRRQPDTLEVQQMRSQAKEDKQRRAAEQAKVALERKERQQMEKEYKEMKQKVE 353
BLAST of FERM domain containing-1 vs. Ensembl Fly
Match: Moe (gene:FBgn0011661 transcript:FBtr0071277) HSP 1 Score: 454.521 bits (1168), Expect = 1.719e-153 Identity = 271/577 (46.97%), Postives = 380/577 (65.86%), Query Frame = 3
Query: 66 KPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELE----EMHARL-----AENKRALEHAKANADEDRERLLKENEQIQLQISKKN-------IEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVT--LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
K ++V+++T+++ELEF++ + TTG++LF+QVVKT+ LRE WFFGL + DSKG TW+K +K+ QDV K+ PLQF+F K+YPE+V EL+Q++T RLFYLQV+N IL IYCPPE+SVLLASYA Q ++GD + F+ D LLP+RVI+QH++SK +W ++I+ ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF I+NKKG++L LGVDALGL+IY+QD++LTP IGFPWSEI+N+S+S KKF IK DK + +F+FF RINK IL + MGNH+LY++RRKPDTI++QQMKAQA EE+ KQ ++K+ A+E E+K + E RLK+ E E +QR L E + IR LEE L+Q K ELE E+ A L A+N A+E K + +++ E ++IQ +++ K+ EVE + + L + E + DV+ L + E + D E+ R+T N L +QLK+L QDL + R K D IH EN R G DK+KTLR+IR+GNTK+RVD+FE +
Sbjct: 4 KALNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNK--TTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQEREKLQLALAARERAEKKQQEYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQM--EVQRIQDEVNAKDEETKRLQDEVEDARRKQAEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDLDTDEHIKDPIED-RRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM 575
BLAST of FERM domain containing-1 vs. Ensembl Fly
Match: Moe (gene:FBgn0011661 transcript:FBtr0071276) HSP 1 Score: 454.521 bits (1168), Expect = 1.719e-153 Identity = 271/577 (46.97%), Postives = 380/577 (65.86%), Query Frame = 3
Query: 66 KPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELE----EMHARL-----AENKRALEHAKANADEDRERLLKENEQIQLQISKKN-------IEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVT--LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
K ++V+++T+++ELEF++ + TTG++LF+QVVKT+ LRE WFFGL + DSKG TW+K +K+ QDV K+ PLQF+F K+YPE+V EL+Q++T RLFYLQV+N IL IYCPPE+SVLLASYA Q ++GD + F+ D LLP+RVI+QH++SK +W ++I+ ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF I+NKKG++L LGVDALGL+IY+QD++LTP IGFPWSEI+N+S+S KKF IK DK + +F+FF RINK IL + MGNH+LY++RRKPDTI++QQMKAQA EE+ KQ ++K+ A+E E+K + E RLK+ E E +QR L E + IR LEE L+Q K ELE E+ A L A+N A+E K + +++ E ++IQ +++ K+ EVE + + L + E + DV+ L + E + D E+ R+T N L +QLK+L QDL + R K D IH EN R G DK+KTLR+IR+GNTK+RVD+FE +
Sbjct: 4 KALNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNK--TTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQEREKLQLALAARERAEKKQQEYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQM--EVQRIQDEVNAKDEETKRLQDEVEDARRKQAEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDLDTDEHIKDPIED-RRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM 575
BLAST of FERM domain containing-1 vs. Ensembl Fly
Match: Moe (gene:FBgn0011661 transcript:FBtr0071269) HSP 1 Score: 454.521 bits (1168), Expect = 1.719e-153 Identity = 271/577 (46.97%), Postives = 380/577 (65.86%), Query Frame = 3
Query: 66 KPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELE----EMHARL-----AENKRALEHAKANADEDRERLLKENEQIQLQISKKN-------IEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVT--LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
K ++V+++T+++ELEF++ + TTG++LF+QVVKT+ LRE WFFGL + DSKG TW+K +K+ QDV K+ PLQF+F K+YPE+V EL+Q++T RLFYLQV+N IL IYCPPE+SVLLASYA Q ++GD + F+ D LLP+RVI+QH++SK +W ++I+ ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF I+NKKG++L LGVDALGL+IY+QD++LTP IGFPWSEI+N+S+S KKF IK DK + +F+FF RINK IL + MGNH+LY++RRKPDTI++QQMKAQA EE+ KQ ++K+ A+E E+K + E RLK+ E E +QR L E + IR LEE L+Q K ELE E+ A L A+N A+E K + +++ E ++IQ +++ K+ EVE + + L + E + DV+ L + E + D E+ R+T N L +QLK+L QDL + R K D IH EN R G DK+KTLR+IR+GNTK+RVD+FE +
Sbjct: 4 KALNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNK--TTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQEREKLQLALAARERAEKKQQEYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQM--EVQRIQDEVNAKDEETKRLQDEVEDARRKQAEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDLDTDEHIKDPIED-RRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM 575
BLAST of FERM domain containing-1 vs. Ensembl Fly
Match: Moe (gene:FBgn0011661 transcript:FBtr0071275) HSP 1 Score: 454.521 bits (1168), Expect = 1.719e-153 Identity = 271/577 (46.97%), Postives = 380/577 (65.86%), Query Frame = 3
Query: 66 KPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELE----EMHARL-----AENKRALEHAKANADEDRERLLKENEQIQLQISKKN-------IEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVT--LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
K ++V+++T+++ELEF++ + TTG++LF+QVVKT+ LRE WFFGL + DSKG TW+K +K+ QDV K+ PLQF+F K+YPE+V EL+Q++T RLFYLQV+N IL IYCPPE+SVLLASYA Q ++GD + F+ D LLP+RVI+QH++SK +W ++I+ ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF I+NKKG++L LGVDALGL+IY+QD++LTP IGFPWSEI+N+S+S KKF IK DK + +F+FF RINK IL + MGNH+LY++RRKPDTI++QQMKAQA EE+ KQ ++K+ A+E E+K + E RLK+ E E +QR L E + IR LEE L+Q K ELE E+ A L A+N A+E K + +++ E ++IQ +++ K+ EVE + + L + E + DV+ L + E + D E+ R+T N L +QLK+L QDL + R K D IH EN R G DK+KTLR+IR+GNTK+RVD+FE +
Sbjct: 4 KALNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNK--TTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQEREKLQLALAARERAEKKQQEYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQM--EVQRIQDEVNAKDEETKRLQDEVEDARRKQAEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDLDTDEHIKDPIED-RRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM 575
BLAST of FERM domain containing-1 vs. Ensembl Fly
Match: Moe (gene:FBgn0011661 transcript:FBtr0071274) HSP 1 Score: 454.521 bits (1168), Expect = 1.719e-153 Identity = 271/577 (46.97%), Postives = 380/577 (65.86%), Query Frame = 3
Query: 66 KPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELE----EMHARL-----AENKRALEHAKANADEDRERLLKENEQIQLQISKKN-------IEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVT--LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
K ++V+++T+++ELEF++ + TTG++LF+QVVKT+ LRE WFFGL + DSKG TW+K +K+ QDV K+ PLQF+F K+YPE+V EL+Q++T RLFYLQV+N IL IYCPPE+SVLLASYA Q ++GD + F+ D LLP+RVI+QH++SK +W ++I+ ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF I+NKKG++L LGVDALGL+IY+QD++LTP IGFPWSEI+N+S+S KKF IK DK + +F+FF RINK IL + MGNH+LY++RRKPDTI++QQMKAQA EE+ KQ ++K+ A+E E+K + E RLK+ E E +QR L E + IR LEE L+Q K ELE E+ A L A+N A+E K + +++ E ++IQ +++ K+ EVE + + L + E + DV+ L + E + D E+ R+T N L +QLK+L QDL + R K D IH EN R G DK+KTLR+IR+GNTK+RVD+FE +
Sbjct: 4 KALNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNK--TTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQEREKLQLALAARERAEKKQQEYEDRLKQMQEDMERSQRDLLEAQDMIRRLEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQM--EVQRIQDEVNAKDEETKRLQDEVEDARRKQAEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDLDTDEHIKDPIED-RRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM 575
BLAST of FERM domain containing-1 vs. Ensembl Zebrafish
Match: ezrb (ezrin b [Source:ZFIN;Acc:ZDB-GENE-050803-1]) HSP 1 Score: 417.157 bits (1071), Expect = 9.829e-139 Identity = 213/439 (48.52%), Postives = 310/439 (70.62%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKE---------------SNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQIS 1331
M KP++V+++T+++ELEF+V +TTG++LF+QVVKT+ LRE W+FGL + DSKG+ TWLK ++K+++QDV K+ PLQFKF K++PE+V +EL+Q++TQ+LF++QV++ IL IYCPPE++VLLASY+ Q K+GDF +EL ++ ++ LLP+RV++QH++S+ +W E I ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF+IKNKKG+EL LGVDALGL+IY++D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE++ KQ + ++ E+ +E IER+ ME KE NE+ E QR Q ++R +E ARL ++A AK + LK EQ+ +++
Sbjct: 1 MPKPVNVRVTTMDAELEFAVQPSTTGKQLFDQVVKTIGLREIWYFGLQYMDSKGYLTWLKLDKKVSSQDVKKENPLQFKFRAKFFPEDVADELIQDITQKLFFMQVKDGILSDEIYCPPETAVLLASYSVQAKFGDFSKEL--HRPGYLTSERLLPQRVLDQHKLSREQWEERIQVWHEEHRGMLREDAMLEYLKIAQDLEMYGVNYFDIKNKKGTELWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKQQKQMERAQLENEKKRREAIEREKEQMEREKKELMMQLYQFEERTKKVENELQEQMQR---------------AMQLQHERRLADEEAARLEAERQAALLAKEELARQAQDQLKSQEQLAAELA 422 HSP 2 Score: 73.1738 bits (178), Expect = 4.557e-13 Identity = 43/87 (49.43%), Postives = 52/87 (59.77%), Query Frame = 3
Query: 1482 DVTLGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
D+ G F D R EE R T N +Q QL +L +L + R K D +H EN R G DK+KTLRQIRQGNTK+R+D FEAL
Sbjct: 499 DLQTGG--FNDHRLEEERITEAEKNERVQKQLLALTSELAQARDDTKKTQNDLLHTENVRAGRDKYKTLRQIRQGNTKQRIDEFEAL 583
BLAST of FERM domain containing-1 vs. Ensembl Zebrafish
Match: ezrb (ezrin b [Source:ZFIN;Acc:ZDB-GENE-050803-1]) HSP 1 Score: 417.157 bits (1071), Expect = 9.829e-139 Identity = 213/439 (48.52%), Postives = 310/439 (70.62%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKE---------------SNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQIS 1331
M KP++V+++T+++ELEF+V +TTG++LF+QVVKT+ LRE W+FGL + DSKG+ TWLK ++K+++QDV K+ PLQFKF K++PE+V +EL+Q++TQ+LF++QV++ IL IYCPPE++VLLASY+ Q K+GDF +EL ++ ++ LLP+RV++QH++S+ +W E I ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF+IKNKKG+EL LGVDALGL+IY++D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE++ KQ + ++ E+ +E IER+ ME KE NE+ E QR Q ++R +E ARL ++A AK + LK EQ+ +++
Sbjct: 1 MPKPVNVRVTTMDAELEFAVQPSTTGKQLFDQVVKTIGLREIWYFGLQYMDSKGYLTWLKLDKKVSSQDVKKENPLQFKFRAKFFPEDVADELIQDITQKLFFMQVKDGILSDEIYCPPETAVLLASYSVQAKFGDFSKEL--HRPGYLTSERLLPQRVLDQHKLSREQWEERIQVWHEEHRGMLREDAMLEYLKIAQDLEMYGVNYFDIKNKKGTELWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKQQKQMERAQLENEKKRREAIEREKEQMEREKKELMMQLYQFEERTKKVENELQEQMQR---------------AMQLQHERRLADEEAARLEAERQAALLAKEELARQAQDQLKSQEQLAAELA 422 HSP 2 Score: 73.1738 bits (178), Expect = 4.557e-13 Identity = 43/87 (49.43%), Postives = 52/87 (59.77%), Query Frame = 3
Query: 1482 DVTLGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
D+ G F D R EE R T N +Q QL +L +L + R K D +H EN R G DK+KTLRQIRQGNTK+R+D FEAL
Sbjct: 499 DLQTGG--FNDHRLEEERITEAEKNERVQKQLLALTSELAQARDDTKKTQNDLLHTENVRAGRDKYKTLRQIRQGNTKQRIDEFEAL 583
BLAST of FERM domain containing-1 vs. Ensembl Zebrafish
Match: msna (moesin a [Source:ZFIN;Acc:ZDB-GENE-021211-2]) HSP 1 Score: 410.223 bits (1053), Expect = 5.378e-136 Identity = 180/302 (59.60%), Postives = 246/302 (81.46%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M K ISV+++T+++ELEF++ +TTG++LF+QVVKT+ LRE WFFGL ++D+KGF TWLK N+K+TAQDV K+ PL FKF K+YPE+V EL+QE TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KY D+ ++ +++ + LLP+RV+EQH+++K +W E I ++ HK MLRE++++EYLK+AQDLEM+GVNYF+IKNKKGSEL LGVDALGL+IY+Q++K+TP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 MPKTISVRVTTMDAELEFAIQPSTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQEATQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQAKYADYNKDA--HTPGYLSNEKLLPQRVLEQHKLNKEQWEERIQVWHEEHKGMLREDSMMEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDKMTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAQRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 68.1662 bits (165), Expect = 1.497e-11 Identity = 39/84 (46.43%), Postives = 46/84 (54.76%), Query Frame = 3
Query: 1491 LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
L S DR EE R T N +Q L +L +L R K D IH EN R G DK+KTLRQIR GNTK+R+D FE +
Sbjct: 496 LTSAAAYKDRSEEERMTEAEKNERVQKHLLALTSELANARDETKKTQNDIIHAENVRAGRDKYKTLRQIRSGNTKQRIDEFECM 579
BLAST of FERM domain containing-1 vs. Ensembl Zebrafish
Match: msnb (moesin b [Source:ZFIN;Acc:ZDB-GENE-030717-7]) HSP 1 Score: 404.06 bits (1037), Expect = 1.153e-133 Identity = 178/302 (58.94%), Postives = 242/302 (80.13%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M KPI+V+++T+++ELEF++ ++TTG++LF+QVVKT+ LRE W+FGL ++DSKGF TWLK N+++TAQDV K+ PL KF K+YPE+V EL+QE TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q K+ D+ E ++ D LLP+R +EQH+++K +W + I ++ HK M RE+A++EYLK++QDLEM+GVNYF+IKNKKGSEL LGVDALGL+IY++ +KLTP IGFPWSEI+N+S+++KKF IK DK S +FVF+ RINK IL + MGNHDLY++RRKPDTI
Sbjct: 1 MQKPINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSE--HHIPGYLCRDKLLPQRFLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTI 300 HSP 2 Score: 76.2554 bits (186), Expect = 5.071e-14 Identity = 40/76 (52.63%), Postives = 52/76 (68.42%), Query Frame = 3
Query: 1515 DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
DR EE R T N LQ +L++L+ +L + R +K D IH EN RLG DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 504 DRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM 579
BLAST of FERM domain containing-1 vs. Ensembl Zebrafish
Match: msnb (moesin b [Source:ZFIN;Acc:ZDB-GENE-030717-7]) HSP 1 Score: 399.438 bits (1025), Expect = 6.100e-132 Identity = 176/298 (59.06%), Postives = 240/298 (80.54%), Query Frame = 3
Query: 72 ISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
I+V+++T+++ELEF++ ++TTG++LF+QVVKT+ LRE W+FGL ++DSKGF TWLK N+++TAQDV K+ PL KF K+YPE+V EL+QE TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q K+ D+ E ++ D LLP+RV+EQH+++K +W + I ++ HK M RE+A++EYLK++QDLEM+GVNYF+IKNKKGSEL LGVDALGL+IY++ +KLTP IGFPWSEI+N+S+++KKF IK DK S +FVF+ RINK IL + MGNHDLY++RRKPDTI
Sbjct: 3 INVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSE--HHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTI 298 HSP 2 Score: 76.2554 bits (186), Expect = 4.836e-14 Identity = 40/76 (52.63%), Postives = 52/76 (68.42%), Query Frame = 3
Query: 1515 DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
DR EE R T N LQ +L++L+ +L + R +K D IH EN RLG DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 502 DRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM 577
BLAST of FERM domain containing-1 vs. Ensembl Xenopus
Match: hgd (homogentisate 1,2-dioxygenase [Source:Xenbase;Acc:XB-GENE-996013]) HSP 1 Score: 420.239 bits (1079), Expect = 7.805e-140 Identity = 184/302 (60.93%), Postives = 249/302 (82.45%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
+++PISV+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL ++D+KGF TWLK N+K+TAQDV K PL FKF K+YPE+V EL+Q++TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E +++ D LLP+RV+EQH++SK +W E I ++ H+ MLRE+AI+EYLK+AQDLEM+GVNYF+IKNKKGSEL LGVDALGL+IY+Q+++LTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 VAQPISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKDSPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQAKYGDYNKEC--QKPGYLSGDKLLPQRVLEQHKLSKDQWEERIHVWHEEHRGMLREDAILEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 70.8626 bits (172), Expect = 3.499e-12 Identity = 39/84 (46.43%), Postives = 49/84 (58.33%), Query Frame = 3
Query: 1491 LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
L S + DR EE R T N +Q L L+ +L R K D +H EN R G DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 497 LKSEAMIKDRSEEDRTTEAEKNERVQKHLLLLSSELANARDETKKTANDLLHAENVRAGRDKYKTLRQIRQGNTKQRIDEFESM 580
BLAST of FERM domain containing-1 vs. Ensembl Xenopus
Match: RDX (radixin [Source:NCBI gene;Acc:447978]) HSP 1 Score: 418.698 bits (1075), Expect = 2.510e-139 Identity = 199/340 (58.53%), Postives = 270/340 (79.41%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLA 1079
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVRKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYSKEA--HKPGYLANDRLLPQRVLEQHKLTKEQWEERIQTWHEEHRSMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIA 333 HSP 2 Score: 70.8626 bits (172), Expect = 3.627e-12 Identity = 38/84 (45.24%), Postives = 53/84 (63.10%), Query Frame = 3
Query: 1491 LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
L S ++ R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 487 LSSEGVMNHRSEEERLTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 570
BLAST of FERM domain containing-1 vs. Ensembl Xenopus
Match: hgd (homogentisate 1,2-dioxygenase [Source:Xenbase;Acc:XB-GENE-996013]) HSP 1 Score: 418.698 bits (1075), Expect = 3.613e-139 Identity = 185/302 (61.26%), Postives = 247/302 (81.79%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M K ISV+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL ++D+KGF TWLK N+K+TAQDV K PL FKF K+YPE+V EL+Q++TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E +++ D LLP+RV+EQH++SK +W E I ++ H+ MLRE+AI+EYLK+AQDLEM+GVNYF+IKNKKGSEL LGVDALGL+IY+Q+++LTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKDSPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQAKYGDYNKEC--QKPGYLSGDKLLPQRVLEQHKLSKDQWEERIHVWHEEHRGMLREDAILEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 70.8626 bits (172), Expect = 3.687e-12 Identity = 39/84 (46.43%), Postives = 49/84 (58.33%), Query Frame = 3
Query: 1491 LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
L S + DR EE R T N +Q L L+ +L R K D +H EN R G DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 497 LKSEAMIKDRSEEDRTTEAEKNERVQKHLLLLSSELANARDETKKTANDLLHAENVRAGRDKYKTLRQIRQGNTKQRIDEFESM 580
BLAST of FERM domain containing-1 vs. Ensembl Xenopus
Match: RDX (radixin [Source:NCBI gene;Acc:447978]) HSP 1 Score: 418.698 bits (1075), Expect = 4.007e-139 Identity = 199/340 (58.53%), Postives = 270/340 (79.41%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLA 1079
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVRKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYSKEA--HKPGYLANDRLLPQRVLEQHKLTKEQWEERIQTWHEEHRSMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIA 333 HSP 2 Score: 70.8626 bits (172), Expect = 3.433e-12 Identity = 38/84 (45.24%), Postives = 53/84 (63.10%), Query Frame = 3
Query: 1491 LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
L S ++ R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 507 LSSEGVMNHRSEEERLTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 590
BLAST of FERM domain containing-1 vs. Ensembl Xenopus
Match: hgd (homogentisate 1,2-dioxygenase [Source:Xenbase;Acc:XB-GENE-996013]) HSP 1 Score: 418.313 bits (1074), Expect = 5.982e-139 Identity = 184/299 (61.54%), Postives = 246/299 (82.27%), Query Frame = 3
Query: 69 PISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
PISV+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL ++D+KGF TWLK N+K+TAQDV K PL FKF K+YPE+V EL+Q++TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E +++ D LLP+RV+EQH++SK +W E I ++ H+ MLRE+AI+EYLK+AQDLEM+GVNYF+IKNKKGSEL LGVDALGL+IY+Q+++LTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 6 PISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKDSPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQAKYGDYNKEC--QKPGYLSGDKLLPQRVLEQHKLSKDQWEERIHVWHEEHRGMLREDAILEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 302 HSP 2 Score: 70.8626 bits (172), Expect = 3.480e-12 Identity = 39/84 (46.43%), Postives = 49/84 (58.33%), Query Frame = 3
Query: 1491 LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
L S + DR EE R T N +Q L L+ +L R K D +H EN R G DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 499 LKSEAMIKDRSEEDRTTEAEKNERVQKHLLLLSSELANARDETKKTANDLLHAENVRAGRDKYKTLRQIRQGNTKQRIDEFESM 582
BLAST of FERM domain containing-1 vs. Ensembl Mouse
Match: Rdx (radixin [Source:MGI Symbol;Acc:MGI:97887]) HSP 1 Score: 421.009 bits (1081), Expect = 4.212e-140 Identity = 201/340 (59.12%), Postives = 272/340 (80.00%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLA 1079
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E I P ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKE-IHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIA 333 HSP 2 Score: 70.8626 bits (172), Expect = 2.757e-12 Identity = 38/84 (45.24%), Postives = 53/84 (63.10%), Query Frame = 3
Query: 1491 LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
L S ++ R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 500 LSSEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 583
BLAST of FERM domain containing-1 vs. Ensembl Mouse
Match: Rdx (radixin [Source:MGI Symbol;Acc:MGI:97887]) HSP 1 Score: 421.009 bits (1081), Expect = 4.212e-140 Identity = 201/340 (59.12%), Postives = 272/340 (80.00%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLA 1079
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E I P ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKE-IHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIA 333 HSP 2 Score: 70.8626 bits (172), Expect = 2.757e-12 Identity = 38/84 (45.24%), Postives = 53/84 (63.10%), Query Frame = 3
Query: 1491 LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
L S ++ R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 500 LSSEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 583
BLAST of FERM domain containing-1 vs. Ensembl Mouse
Match: Msn (moesin [Source:MGI Symbol;Acc:MGI:97167]) HSP 1 Score: 419.853 bits (1078), Expect = 9.140e-140 Identity = 183/302 (60.60%), Postives = 248/302 (82.12%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M K ISV+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL ++D+K F TWLK N+K+TAQDV K+ PL FKF K+YPE+V EL+Q++TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGDF +E+ + ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF+IKNKKGSEL LGVDALGL+IY+Q+++LTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKAFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEV--HKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 77.411 bits (189), Expect = 1.945e-14 Identity = 40/79 (50.63%), Postives = 49/79 (62.03%), Query Frame = 3
Query: 1506 FVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
DR EE R T N +Q LK+L +L R +K D IH EN RLG DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 499 MAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM 577
BLAST of FERM domain containing-1 vs. Ensembl Mouse
Match: Rdx (radixin [Source:MGI Symbol;Acc:MGI:97887]) HSP 1 Score: 419.853 bits (1078), Expect = 2.053e-139 Identity = 201/340 (59.12%), Postives = 272/340 (80.00%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLA 1079
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E I P ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKE-IHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIA 333 HSP 2 Score: 70.8626 bits (172), Expect = 2.870e-12 Identity = 38/84 (45.24%), Postives = 53/84 (63.10%), Query Frame = 3
Query: 1491 LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
L S ++ R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 500 LSSEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 583
BLAST of FERM domain containing-1 vs. Ensembl Mouse
Match: Rdx (radixin [Source:MGI Symbol;Acc:MGI:97887]) HSP 1 Score: 411.764 bits (1057), Expect = 2.527e-139 Identity = 201/340 (59.12%), Postives = 272/340 (80.00%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLA 1079
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E I P ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKE-IHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIA 333
BLAST of FERM domain containing-1 vs. UniProt/SwissProt
Match: sp|Q29GR8|MOEH_DROPS (Moesin/ezrin/radixin homolog 1 OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=Moe PE=3 SV=3) HSP 1 Score: 454.136 bits (1167), Expect = 4.660e-152 Identity = 269/575 (46.78%), Postives = 375/575 (65.22%), Query Frame = 3
Query: 66 KPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQK-------RELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKN-------IEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVT--LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
K ++V+++T+++ELEF++ + TTG++LF+QVVKT+ LRE WFFGL + DSKG TW+K +K+ QDV K+ PLQF+F K+YPE+V EL+Q++T RLFYLQV+N IL IYCPPE+SVLLASYA Q ++GD + F+ D LLP+RVI+QH++SK +W ++I+ ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF I+NKKG++L LGVDALGL+IY+QD++LTP IGFPWSEI+N+S+S KKF IK DK + +F+FF RINK IL + MGNH+LY++RRKPDTI++QQMKAQA EE+ KQ ++K+ A+E E+K + E RLK+ E E +QR L E + IR LEE L+Q K +EL+ M RL E K K +E+ E ++IQ +++ K+ EVE + + L + E + DV+ L + E + D E+ R+T N L +QLK+L QDL + R K D IH EN R G DK+KTLR+IR+GNTK+RVD+FE +
Sbjct: 22 KTLNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKVMNQDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNK--TTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQEREKLQLALAARERAEKKQQEYEDRLKQMQEEMERSQRDLLEAQEMIRRLEEQLKQLQAAKDELELRQKELQSMLQRLEEAKNMEAVEKIKLEEEIMAKQMEVQRIQDEVNAKDEETKRLQDEVEEARRKQAEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDLDTDEHIKDPIED-RRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKGNTKRRVDQFENM 593
BLAST of FERM domain containing-1 vs. UniProt/SwissProt
Match: sp|P26038|MOES_HUMAN (Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3) HSP 1 Score: 422.165 bits (1084), Expect = 8.048e-140 Identity = 184/302 (60.93%), Postives = 249/302 (82.45%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M K ISV+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL ++D+KGF TWLK N+K+TAQDV K+ PL FKF K+YPE+V EL+Q++TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGDF +E+ + ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF+IKNKKGSEL LGVDALGL+IY+Q+++LTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 MPKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEV--HKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 77.411 bits (189), Expect = 1.524e-13 Identity = 40/76 (52.63%), Postives = 49/76 (64.47%), Query Frame = 3
Query: 1515 DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
DR EE R T N +Q LK+L +L R +K D IH EN RLG DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 502 DRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM 577
BLAST of FERM domain containing-1 vs. UniProt/SwissProt
Match: sp|P26044|RADI_PIG (Radixin OS=Sus scrofa OX=9823 GN=RDX PE=2 SV=1) HSP 1 Score: 422.165 bits (1084), Expect = 1.001e-139 Identity = 224/433 (51.73%), Postives = 314/433 (72.52%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELR---------LKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQIS 1331
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E I P ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++I+EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A+ E ++ ++ E T + +E E + R+ EL ++ R K E E RL + +RA E AK+ + +K EQ+ +++
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKE-IHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSIMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIAEKEKERIEREKEELMERLRQIEEQTMKAQKELEEQTRKALELDQERKRAKEEAE----RLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELA 422 HSP 2 Score: 68.5514 bits (166), Expect = 9.805e-11 Identity = 36/78 (46.15%), Postives = 50/78 (64.10%), Query Frame = 3
Query: 1509 VDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
++ R EE R T N + QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 506 MNHRSEEERVTETQKNERVNKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 583
BLAST of FERM domain containing-1 vs. UniProt/SwissProt
Match: sp|Q2HJ49|MOES_BOVIN (Moesin OS=Bos taurus OX=9913 GN=MSN PE=2 SV=3) HSP 1 Score: 421.394 bits (1082), Expect = 1.337e-139 Identity = 184/302 (60.93%), Postives = 250/302 (82.78%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M K I+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL ++D+KGF TWLK N+K+TAQDV K+ PL FKF K+YPE+V EL+Q++TQRLF+LQV+ DIL+ IYCPPE++VLLASYA Q KYGDF +E+ + ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF+IKNKKGSEL LGVDALGL+IY+Q+++LTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 MPKTINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREIWFFGLQYQDTKGFFTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEDILNDDIYCPPETAVLLASYAVQSKYGDFNKEV--HKSGYLAGDRLLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 77.411 bits (189), Expect = 1.678e-13 Identity = 40/76 (52.63%), Postives = 49/76 (64.47%), Query Frame = 3
Query: 1515 DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
DR EE R T N +Q LK+L +L R +K D IH EN RLG DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 502 DRSEEERTTEAEKNERVQKHLKALTSELANARDESKKTANDMIHAENMRLGRDKYKTLRQIRQGNTKQRIDEFESM 577
BLAST of FERM domain containing-1 vs. UniProt/SwissProt
Match: sp|P26043|RADI_MOUSE (Radixin OS=Mus musculus OX=10090 GN=Rdx PE=1 SV=3) HSP 1 Score: 421.009 bits (1081), Expect = 2.947e-139 Identity = 201/340 (59.12%), Postives = 272/340 (80.00%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLA 1079
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KYGD+ +E I P ++ D LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ D+KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R++A
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKE-IHKPG-YLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQ-----LERAQLENEKKKREIA 333 HSP 2 Score: 70.8626 bits (172), Expect = 1.929e-11 Identity = 38/84 (45.24%), Postives = 53/84 (63.10%), Query Frame = 3
Query: 1491 LGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
L S ++ R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 500 LSSEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 583
BLAST of FERM domain containing-1 vs. TrEMBL
Match: I1ZIJ8 (FERM domain containing-1 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 879.396 bits (2271), Expect = 0.000e+0 Identity = 504/504 (100.00%), Postives = 504/504 (100.00%), Query Frame = 3
Query: 231 WLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKNIEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVTLGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
WLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIEMQQMKAQAEEERKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQLEEYERKIRELEELLEQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKNIEVEHGSEELRQRQEELERLRAEREELEAKASMLEEAAKAKEKSKEEDVTLGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL
Sbjct: 1 WLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIEMQQMKAQAEEERKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQLEEYERKIRELEELLEQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKNIEVEHGSEELRQRQEELERLRAEREELEAKASMLEEAAKAKEKSKEEDVTLGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 504
BLAST of FERM domain containing-1 vs. TrEMBL
Match: A0A4D5R907 (Moesin/ezrin/radixin-like protein 1 OS=Scolopendra viridis OX=118503 PE=4 SV=1) HSP 1 Score: 480.715 bits (1236), Expect = 2.717e-160 Identity = 271/574 (47.21%), Postives = 389/574 (67.77%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRL--------KESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKNIEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVTLGSMEFVDD-----RREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
M KP++V+++T+++E+EF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+ QDV K+ PLQFKF K+YPE+V E++Q++T RLFYLQV+N IL IYCPPE+SVLLASYA Q KYGD+ +E+ + F+ D LLP+RV +QH++SKA+W E I Y H+ MLRE+A++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY++D+KLTP IGFPWSEI+N+S++++KF IK DK + +FVFF RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ ++K+ RE +A+E E+K + E R+ + NE++E Q Q+ E +++EL++ + R++ ELEEM +L+E+K + +E+ E +IQ ++ K+ E E+ + + + + A + E + + +G+ DD R EE RQT N LQ+QLK L+++L + + K+ D +H EN + G DK+KTLR+IR+GNTK+RVD+FE +
Sbjct: 1 MPKPVNVRVTTMDAEMEFAIQPNTTGKQLFDQVVKTIGLREIWFFGLQYTDSKGYTTWLKLNKKVLNQDVQKETPLQFKFRAKFYPEDVAEEIIQDITLRLFYLQVKNGILSDEIYCPPETSVLLASYAVQAKYGDYNKEI--QKSGFLANDRLLPQRVHDQHKMSKAEWEERIATWYAEHRGMLREDAMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDRKFVIKPIDKKAPDFVFFAPRLRINKRILSLCMGNHELYMRRRKPDTIEVQQMKAQAREEKLAKQQEREKLQREIIAREMAEKKHQEYEDRIRAMQQEMERRQNELSEA-QEQIRRLEEQLKELQKSKDMLERKQNELEEMMRKLSEDKEMELQERTKLEEEIRVKQDEVSKIQEEVQLKDEETRRLQYEVEEARRKQDEANAALLAATTPQHHHVTENEHDENDELLNGEVGADLSQDDMINLPRPEEERQTQAEKNERLQSQLKILSKELEQTKDETKLTMNDLLHQENVKQGRDKYKTLREIRKGNTKRRVDQFENM 571
BLAST of FERM domain containing-1 vs. TrEMBL
Match: A0A0K2UFE4 (Moesin/ezrin/radixin homolog 1like [Bombyx mori] OS=Lepeophtheirus salmonis OX=72036 PE=4 SV=1) HSP 1 Score: 477.633 bits (1228), Expect = 3.395e-159 Identity = 274/571 (47.99%), Postives = 390/571 (68.30%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQIS----------KKNIEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVTLGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
M K ++V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + D+KGF TWLK N+K+ QDV K+ PLQFKF K+YPE+V EL+Q++T RLFYLQV+N IL IYCPPE+SVLLASYA Q K+GDF+++ F+ D LLPERV +QH +++ +W + I + Y HK M+RE+A++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY++D++LTP IGFPWSEI+N+S++++KF IK D + NFVFF RINK IL + MGNH+LY++RRKPDTIE+QQMKAQ +EE+ KQ ++K+ RE A+E+ ER A+ E RLK E E Q+ L E + +I++LE +L ++ K+ELEE L + R LE K E+R RL E + Q +++ ++N+E++ ++ R++ EE + E+ + + E D+ + S + +DD + R + N LQNQLKSL +DL+ R + +D IH EN + G DK+KTLR++R+GNTK+RVD+FE +
Sbjct: 1 MPKAVNVRVTTIDAELEFAIQPNTTGKQLFDQVVKTIGLREIWFFGLQYTDTKGFSTWLKLNKKVMVQDVKKETPLQFKFRAKFYPEDVAEELIQDITLRLFYLQVKNAILSDEIYCPPETSVLLASYAVQSKHGDFQKDF--HVAGFLANDRLLPERVTQQHRLNREQWEKRITEWYSEHKGMMREDAMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEKDDRLTPKIGFPWSEIRNISFNDRKFVIKPIDAKAPNFVFFAPRLRINKRILTLCMGNHELYMRRRKPDTIEVQQMKAQNKEEKLAKQQEREKLQREIAAREKAERIQAEYEDRLKAMQEDMEKRQKALLEAQEQIKKLESVLRETQDAKQELEESQNELKDMMRRLEDDKNLEIEERTRLQDEIARKQSEVNDIYTQVQTKEQENMELQKEMDDARRKHEEATIALVAATTTPKHHHLEEDDNDDEVSNSERDLHVPS-DPIDDPVSD-RLLLVERNERLQNQLKSLKEDLSHTRDEGEETTMDRIHKENVKQGRDKYKTLREVRKGNTKRRVDQFENM 567
BLAST of FERM domain containing-1 vs. TrEMBL
Match: A0A226DXY8 (Moesin/ezrin/radixin 1 OS=Folsomia candida OX=158441 GN=Fcan01_14987 PE=4 SV=1) HSP 1 Score: 468.003 bits (1203), Expect = 2.302e-155 Identity = 270/569 (47.45%), Postives = 384/569 (67.49%), Query Frame = 3
Query: 72 ISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERL-----LKENE--QIQLQISKKNIEV-----EHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVTLGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
++V+++T+++ELEF++ +TTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+ +QD+ K+ PLQF+F K+YPE+V EL+Q++T RLFYLQV+N IL IYCPPE+SVLLASYA Q KYGD+ +E+ + + D +LP+RV++QH +S+ +W E IV +K HK M+RE+A++EYLK+AQDLEM+GVNYF IKNKKG++L LGVDALGL+IY++++KLTP IGFPWSEI+N+S++++KF IK DK + +FVFF RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ ++K+ RE A+E+ ERK + E RLK E E Q +L E + IR LEE L + K LEE L E LE +K ++++L +K+ E +IQ ++ K+ E E + RQ + + A + ++ + +++ G E+ D + QT N +LQ+QLK L Q+L E R +K +D +H EN R G DK+KTLR+IR+GNTK+RVD+FE +
Sbjct: 7 VNVRVTTMDAELEFAIQPSTTGKQLFDQVVKTIGLREIWFFGLQYVDSKGYQTWLKLNKKVLSQDIKKESPLQFRFRAKFYPEDVAEELIQDITTRLFYLQVKNAILSDDIYCPPETSVLLASYAVQAKYGDYNKEI----HTSLANDRILPQRVMDQHNMSREEWEERIVTWWKEHKGMMREDAMMEYLKIAQDLEMYGVNYFEIKNKKGTDLWLGVDALGLNIYEREDKLTPKIGFPWSEIRNISFNDRKFVIKPIDKKAPDFVFFAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKLAKQQEREKLQREITAREQAERKQQEYEGRLKAMQEEMERRQGELLEAQETIRRLEEQLRALQKAKEHLEERQNELQEMMERLEASKEMEAAEKQKLEDEIRMKQEEVMRIQEEVQAKDEETRRLQEEVEAARKRQEEVANALINATTTPANHHLTDHDDDDELVPNGHSQELYGGDGEYADPV--DGMQTQSQKNEKLQSQLKMLKQELMETRDDSKETTMDKLHKENVRQGRDKYKTLREIRKGNTKRRVDQFENM 569
BLAST of FERM domain containing-1 vs. TrEMBL
Match: A0A293N712 (Radixin, moesin (Fragment) OS=Ornithodoros erraticus OX=265619 PE=4 SV=1) HSP 1 Score: 467.233 bits (1201), Expect = 6.032e-155 Identity = 272/577 (47.14%), Postives = 393/577 (68.11%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXX-------XXXXXXQSNRQKRELEEMHARLAENKRALE-HAKANADEDRERLLKENEQIQLQISKKNIEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVTLGSM--EFVD------DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
M KP++V+++T+++ELEF++ A+TTG++LF+QVVKT+ LRE WFFGL + D+KG+ TWLK N+K+ +QDV K+ PL FKF K+YPE+V +EL+QE+T RLFYLQV++ IL IYCPPE+SVLLASYA Q KYGD+ EL + + +D LLP+RV++QH++SK +W E I + HK++ RE+A++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY++D+KLTP IGFPWSEI+N+S++++KF IK DK + +FVFF RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA+EE+ ++ ++K+ +E A+E ERK + RL++ E E Q++L E + IR ++ E+ R++RELEEM +L EN +A+E K +ED +E +++Q ++++K+ E EE+ + E A A E +E++ G M E + R EE R T +S L +QL+ L+++L+ + K+ D +H EN R G DK+KTLR+IR+GNTK+RVD+FE +
Sbjct: 1 MPKPVNVRVTTMDAELEFAIQASTTGKQLFDQVVKTIGLREIWFFGLQYTDNKGYVTWLKLNKKVLSQDVKKENPLLFKFRAKFYPEDVADELIQEITLRLFYLQVKSTILTDEIYCPPETSVLLASYAVQAKYGDYNTEL--HKSGCLTSDRLLPQRVMDQHKLSKEQWDERITNWWAEHKELPREDAMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDRKFVIKPIDKKAPDFVFFAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAQEEKLARKQEREKLRKETEAREIAERKQQEYAERLRQMQEEMEKRQKELLEAQDTIRRLEEQLRLVQAAKEEFERKQRELEEMMIKL-ENDKAMESEEKLRLEEDIRAKQQEVQRMQDEVNQKDEETRRLQEEVEDARRRQEEAAAALVAASTTPQHHHVAEAEDEGENDEELANGEMGAELTNHENENLPRPEEERSTAVSKQKHLGDQLEMLSKELSAMKDDAKLTRNDILHQENVRQGRDKYKTLREIRKGNTKRRVDQFENM 574
BLAST of FERM domain containing-1 vs. Ensembl Cavefish
Match: msna (moesin [Source:NCBI gene;Acc:103037010]) HSP 1 Score: 413.305 bits (1061), Expect = 2.452e-137 Identity = 181/302 (59.93%), Postives = 247/302 (81.79%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M K ISV+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL ++D+KGFPTWLK N+K+TAQDV K+ PL FKF K++PE+V EL+QE TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KY D+ ++ +++ D LLP+RV+EQH+++K +W E I ++ HK MLRE++++EYLK+AQDLEM+GVNYF+IKNKKG+EL LGVDALGL+IY+Q++K+TP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 MPKTISVRVTTMDAELEFAILPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFPTWLKLNKKVTAQDVRKESPLLFKFRGKFFPEDVSEELIQEATQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQAKYADYNKDA--HTPGYLSNDKLLPQRVLEQHKLNKEQWEERIQVWHEEHKGMLREDSMMEYLKIAQDLEMYGVNYFSIKNKKGTELWLGVDALGLNIYEQNDKMTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 67.781 bits (164), Expect = 1.632e-11 Identity = 37/76 (48.68%), Postives = 45/76 (59.21%), Query Frame = 3
Query: 1515 DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
DR EE R T N +Q L +L+ +L R K D IH EN R G DK+KTLRQIR GNTK+R+D FE +
Sbjct: 504 DRSEEERMTEAEKNERVQKHLLALSSELANARDETKKTQNDIIHAENVRAGRDKYKTLRQIRSGNTKQRIDEFECM 579
BLAST of FERM domain containing-1 vs. Ensembl Cavefish
Match: msna (moesin [Source:NCBI gene;Acc:103037010]) HSP 1 Score: 413.305 bits (1061), Expect = 2.452e-137 Identity = 181/302 (59.93%), Postives = 247/302 (81.79%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M K ISV+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL ++D+KGFPTWLK N+K+TAQDV K+ PL FKF K++PE+V EL+QE TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KY D+ ++ +++ D LLP+RV+EQH+++K +W E I ++ HK MLRE++++EYLK+AQDLEM+GVNYF+IKNKKG+EL LGVDALGL+IY+Q++K+TP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 MPKTISVRVTTMDAELEFAILPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFPTWLKLNKKVTAQDVRKESPLLFKFRGKFFPEDVSEELIQEATQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQAKYADYNKDA--HTPGYLSNDKLLPQRVLEQHKLNKEQWEERIQVWHEEHKGMLREDSMMEYLKIAQDLEMYGVNYFSIKNKKGTELWLGVDALGLNIYEQNDKMTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 67.781 bits (164), Expect = 1.632e-11 Identity = 37/76 (48.68%), Postives = 45/76 (59.21%), Query Frame = 3
Query: 1515 DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
DR EE R T N +Q L +L+ +L R K D IH EN R G DK+KTLRQIR GNTK+R+D FE +
Sbjct: 504 DRSEEERMTEAEKNERVQKHLLALSSELANARDETKKTQNDIIHAENVRAGRDKYKTLRQIRSGNTKQRIDEFECM 579
BLAST of FERM domain containing-1 vs. Ensembl Cavefish
Match: msna (moesin [Source:NCBI gene;Acc:103037010]) HSP 1 Score: 412.92 bits (1060), Expect = 3.143e-137 Identity = 180/302 (59.60%), Postives = 247/302 (81.79%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
+ PISV+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL ++D+KGFPTWLK N+K+TAQDV K+ PL FKF K++PE+V EL+QE TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q KY D+ ++ +++ D LLP+RV+EQH+++K +W E I ++ HK MLRE++++EYLK+AQDLEM+GVNYF+IKNKKG+EL LGVDALGL+IY+Q++K+TP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 LPTPISVRVTTMDAELEFAILPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFPTWLKLNKKVTAQDVRKESPLLFKFRGKFFPEDVSEELIQEATQRLFFLQVKEGILNDDIYCPPETAVLLASYAVQAKYADYNKDA--HTPGYLSNDKLLPQRVLEQHKLNKEQWEERIQVWHEEHKGMLREDSMMEYLKIAQDLEMYGVNYFSIKNKKGTELWLGVDALGLNIYEQNDKMTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 67.781 bits (164), Expect = 1.661e-11 Identity = 37/76 (48.68%), Postives = 45/76 (59.21%), Query Frame = 3
Query: 1515 DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
DR EE R T N +Q L +L+ +L R K D IH EN R G DK+KTLRQIR GNTK+R+D FE +
Sbjct: 504 DRSEEERMTEAEKNERVQKHLLALSSELANARDETKKTQNDIIHAENVRAGRDKYKTLRQIRSGNTKQRIDEFECM 579
BLAST of FERM domain containing-1 vs. Ensembl Cavefish
Match: ENSAMXT00000053554.1 (radixin [Source:NCBI gene;Acc:103042331]) HSP 1 Score: 410.223 bits (1053), Expect = 3.760e-136 Identity = 193/333 (57.96%), Postives = 267/333 (80.18%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKE 1058
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ YCPPE++VLLASY+ Q KYGD+ ++ I P ++ + LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ ++KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + ++ E+ +E
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYTDSKGYTTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDENYCPPETAVLLASYSVQAKYGDYNKD-IHKPG-YLGNERLLPQRVLEQHKLTKEQWEERIQTWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHEDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAQLENEKKKRE 331 HSP 2 Score: 69.3218 bits (168), Expect = 5.127e-12 Identity = 36/78 (46.15%), Postives = 50/78 (64.10%), Query Frame = 3
Query: 1509 VDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
D R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 501 ADQRSEEDRLTEAQKNDRVKKQLQALSSELAQARDDTKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFESM 578
BLAST of FERM domain containing-1 vs. Ensembl Cavefish
Match: ENSAMXT00000054018.1 (radixin [Source:NCBI gene;Acc:103042331]) HSP 1 Score: 410.223 bits (1053), Expect = 4.283e-136 Identity = 193/333 (57.96%), Postives = 267/333 (80.18%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKE 1058
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K+ PLQFKF K++PE+V EL+QE+TQRLF+LQV+ IL+ YCPPE++VLLASY+ Q KYGD+ ++ I P ++ + LLP+RV+EQH+++K +W E I ++ H+ MLRE++++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ ++KLTP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + ++ E+ +E
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYTDSKGYTTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDENYCPPETAVLLASYSVQAKYGDYNKD-IHKPG-YLGNERLLPQRVLEQHKLTKEQWEERIQTWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHEDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAQLENEKKKRE 331 HSP 2 Score: 69.707 bits (169), Expect = 4.869e-12 Identity = 36/78 (46.15%), Postives = 50/78 (64.10%), Query Frame = 3
Query: 1509 VDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
D R EE R T N ++ QL++L+ +L + R K D +H EN + G DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 507 ADQRSEEDRLTEAQKNDRVKKQLQALSSELAQARDDTKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFESM 584
BLAST of FERM domain containing-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008042.1 (pep scaffold:Pmarinus_7.0:GL501310:70164:110449:1 gene:ENSPMAG00000007245.1 transcript:ENSPMAT00000008042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 428.713 bits (1101), Expect = 6.024e-144 Identity = 254/584 (43.49%), Postives = 379/584 (64.90%), Query Frame = 3
Query: 72 ISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTK-------QNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRA-LEHAKANADEDRERLLKENEQIQLQIS-----KKNIEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------XXDVTLGSME-------FVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
I+V+++T+++E+EFS+ G +LF+Q+V+T+ LRE WFFGL + D KG WLK ++K+++ D+ K+ P+QF+F KY+PE+V EL+QE TQRLFYLQ++ IL IYCPPE+ VLLASYA Q KYGD+ +E +P ++ + LLP RV+EQH++S A+W E I + H MLRE+AI+EY+K+AQDLEM+GVNYF+IKNKKG++L LGVDALGL+IY++++KLTP IGFPWSEI+N+S+++KKF I+ DK + +FVF++ + NK IL + MGNH+LY++RR+PD+IE+QQM+AQA+EE+ K +N K K + +++ ER+ ++ +RL+ E Q++L+E ++ LEE ++ ++ ++LE+ R AE RA LEH N +E+L E Q QIS K+N E+E + + + + ++E E + S +ED GS E F +DR EE R T + N ++ QL++L +L + R K +D +H+EN + G DK+KTLRQIRQGNTK+R+D FEA+
Sbjct: 2 INVRVTTLDAEMEFSILHTIYGRQLFDQLVRTIGLREVWFFGLQYTDLKGSIGWLKMDKKVSSHDIRKENPVQFRFRAKYFPEDVSEELIQEATQRLFYLQIKEGILSEEIYCPPETGVLLASYAVQAKYGDYSKE--KNPPGYLANEKLLPSRVLEQHKLSNAQWEERIQAWHSEHNGMLREDAIMEYMKIAQDLEMYGVNYFDIKNKKGTDLQLGVDALGLNIYEKNDKLTPKIGFPWSEIRNISFTDKKFCIRPIDKKAPDFVFYSPRLQTNKRILALCMGNHELYMRRRQPDSIEVQQMRAQAKEEKHVKLQERAFLENEKKKRENAEVERQQSEREKRELMIRLQHVEEQTRIAQKELDEQMQRAARLEEERRKALQEAKKLED-QKRAAEEARARLEHETHNQRMSQEQLAIELAQYTQQISLLEQAKQNKEMEAKEWQQQAELAQDNLQKTKKELDEVMRAPKMMPGLPNPPSPSDLYGGYQEDGDEGSAELPSYGYGFNNDRNEERRVTEMMKNERVKLQLQALNDELAKARDETKKNQMDILHSENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 582
BLAST of FERM domain containing-1 vs. Ensembl Sea Lamprey
Match: nf2b (neurofibromin 2b (merlin) [Source:ZFIN;Acc:ZDB-GENE-040622-3]) HSP 1 Score: 323.939 bits (829), Expect = 9.551e-104 Identity = 166/321 (51.71%), Postives = 227/321 (70.72%), Query Frame = 3
Query: 135 GEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRL 1097
G+ LF+ V +T+ LRETWFFGL F K TWLK +K+ Q+V K+ P+ F+F K+YPE V+ ELVQE+TQ LF+LQV+ ILD I+C PE+SVLLASYA KYG++ L F+ D LLP++VI Q+++++ W E I YK H+ M R+EA +EYLK+AQDLEM+GVNYF IK+KKG + LLGVDALGL I++ ++KL FPWS IKNV YS+K+FTIK DK + F F++ R+NK IL + +GNHD++++RRK D++E+QQMKA A+EE+ KQ + K+ RE+ +E+ ER D+E RL
Sbjct: 6 GKDLFDLVCRTIGLRETWFFGLCFM-VKDTLTWLKMEKKVLEQEVPKEDPICFQFLAKFYPESVDEELVQEITQHLFFLQVKKKILDEEIFCSPEASVLLASYAVLAKYGEYDRSL--HTPGFLAQDELLPKKVINQYQLTQPMWEERITNWYKGHQGMTRDEAEMEYLKIAQDLEMYGVNYFPIKDKKGVDFLLGVDALGLKIFEPNDKLQAKKSFPWSGIKNVQYSDKEFTIKPLDKTTEVFKFYSSKQRVNKLILQLCIGNHDMFMRRRKVDSMEVQQMKAHAKEEKARKQLERQKLDREKQLREDAERAKEDLERRL 323
BLAST of FERM domain containing-1 vs. Ensembl Sea Lamprey
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450]) HSP 1 Score: 120.553 bits (301), Expect = 7.122e-30 Identity = 84/280 (30.00%), Postives = 140/280 (50.00%), Query Frame = 3
Query: 129 TTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIG-FPWSEIKNVSYSNKKFTI------KSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKR 947
G+ LF+QV+ L++ E +FGL F DS WL + + I Q V P F VK+Y E N L +E+T+ LF LQ++ DIL G + CP E++V LA+Y+ Q + GD + ++ ++ +P + E E KW K+ + +A + YL A+ LEM+GV+ ++K + G+E LG+ G+ +++ +NK IG F W +I + + K T+ + + FVF DH + K + ++ +H + R
Sbjct: 3 AVGQDLFDQVMYHLDILEVDYFGLQFMDSAQVSHWLDHTKNIRKQ-VKIGPPYCFHMRVKFYSSE-PNNLHEELTRYLFVLQLKQDILSGKLECPFETAVQLATYSLQAELGDC--DPVEHNPALVSEFRFIPSQSEEMEEAILEKW--------KDCRGQTPAQAELNYLNKAKWLEMYGVDMHSVKGRDGNEYSLGLTPTGVLVFEGENK----IGLFFWPKITRLDFKRTKLTLVVVEDDDQAKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLR 266
BLAST of FERM domain containing-1 vs. Ensembl Sea Lamprey
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450]) HSP 1 Score: 120.168 bits (300), Expect = 9.384e-30 Identity = 83/281 (29.54%), Postives = 141/281 (50.18%), Query Frame = 3
Query: 129 TTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQ-DVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIG-FPWSEIKNVSYSNKKFTI------KSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKR 947
G+ LF+QV+ L++ E +FGL F DS WL + + I Q +G Y + VK+Y E N L +E+T+ LF LQ++ DIL G + CP E++V LA+Y+ Q + GD + ++ ++ +P + E E KW K+ + +A + YL A+ LEM+GV+ ++K + G+E LG+ G+ +++ +NK IG F W +I + + K T+ + + FVF DH + K + ++ +H + R
Sbjct: 3 AVGQDLFDQVMYHLDILEVDYFGLQFMDSAQVSHWLDHTKNIRKQVKIGPPYCFHMR--VKFYSSE-PNNLHEELTRYLFVLQLKQDILSGKLECPFETAVQLATYSLQAELGDC--DPVEHNPALVSEFRFIPSQSEEMEEAILEKW--------KDCRGQTPAQAELNYLNKAKWLEMYGVDMHSVKGRDGNEYSLGLTPTGVLVFEGENK----IGLFFWPKITRLDFKRTKLTLVVVEDDDQAKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLR 266
BLAST of FERM domain containing-1 vs. Ensembl Sea Lamprey
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450]) HSP 1 Score: 119.783 bits (299), Expect = 9.554e-30 Identity = 84/280 (30.00%), Postives = 140/280 (50.00%), Query Frame = 3
Query: 129 TTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIG-FPWSEIKNVSYSNKKFTI------KSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKR 947
G+ LF+QV+ L++ E +FGL F DS WL + + I Q V P F VK+Y E N L +E+T+ LF LQ++ DIL G + CP E++V LA+Y+ Q + GD + ++ ++ +P + E E KW K+ + +A + YL A+ LEM+GV+ ++K + G+E LG+ G+ +++ +NK IG F W +I + + K T+ + + FVF DH + K + ++ +H + R
Sbjct: 3 AVGQDLFDQVMYHLDILEVDYFGLQFMDSAQVSHWLDHTKNIRKQ-VKIGPPYCFHMRVKFYSSE-PNNLHEELTRYLFVLQLKQDILSGKLECPFETAVQLATYSLQAELGDC--DPVEHNPALVSEFRFIPSQSEEMEEAILEKW--------KDCRGQTPAQAELNYLNKAKWLEMYGVDMHSVKGRDGNEYSLGLTPTGVLVFEGENK----IGLFFWPKITRLDFKRTKLTLVVVEDDDQAKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLR 266
BLAST of FERM domain containing-1 vs. Ensembl Nematostella
Match: EDO31608 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXF9]) HSP 1 Score: 387.497 bits (994), Expect = 1.158e-127 Identity = 185/353 (52.41%), Postives = 267/353 (75.64%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQ----VVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKES 1106
M K I+V+++T+++ELEF++ +TTG++LF+Q VVKT+ LRE WFFGL F D+KG +WLK N+K+ +QDV K+ PLQFKF VK++PE+V EL+QEVTQ++F+LQ++ I ++CPPE++VLLASY CQ K+G++ D+ I + LLP+RV++QH +SK +W E I+ +K H M +E+A++EYLK+ QDLEM+GVNYF IKNKK ++L LGVDALGL+IY Q++KLTP IGFPWSEI+N+S+++KKF IK DK + +F+FF+ R NK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ ++ ++ + +E A+ + E +E +LK+S
Sbjct: 1 MPKAINVRVTTMDAELEFAIQPSTTGKQLFDQASNFVVKTIGLREIWFFGLQFTDNKGDASWLKLNKKVMSQDVKKETPLQFKFRVKFFPEDVAEELIQEVTQKMFFLQIKEAIFTSDVFCPPETTVLLASYMCQAKHGEY----TDESAALIKDEKLLPDRVLDQHTLSKEQWDERIILWWKEHGRMAKEDAVIEYLKITQDLEMYGVNYFQIKNKKHTDLYLGVDALGLNIYDQNDKLTPKIGFPWSEIRNISFNDKKFCIKPIDKKAPDFIFFSPRLRSNKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKVRREKERNALVKEAEARTKAENDRKLLEEKLKQS 349 HSP 2 Score: 66.2402 bits (160), Expect = 1.982e-11 Identity = 39/79 (49.37%), Postives = 47/79 (59.49%), Query Frame = 3
Query: 1506 FVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
V DR EE+RQ S L+ L+ DL R K D +H+EN R G DK+KTL+QIRQGNTK RVD+FE L
Sbjct: 508 IVGDRSEENRQPQNRSKA-----LQDLSADLAAARDEKKQTHYDKLHDENARHGRDKYKTLKQIRQGNTKSRVDQFENL 581
BLAST of FERM domain containing-1 vs. Ensembl Nematostella
Match: EDO44119 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWH0]) HSP 1 Score: 337.035 bits (863), Expect = 2.705e-108 Identity = 167/348 (47.99%), Postives = 247/348 (70.98%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKE 1103
M K +V IST+++ELEF + + G +LF+ VV+TL +RETW+FGL F+ G WL++++K+ Q+ + P + K+YPE+V ELVQE+TQ LFYLQV++ IL +CPPE+SVLLASYA Q K+GD+ ++L F+ ++LLP+ VIEQ++++ A W E I Y H + R+EA +EYLKLAQDLEM+GV+YF+I NKKG+ + LG+D GL+IY++DN+L P FPW EIKN+S+ ++ F IKS DK + +F+F T + R NK IL + +GNH+L+ +RRKPDT+E+QQMKA A+EE+ +Q ++K+ E+ A+EE R+ +++ RL+E
Sbjct: 1 MPKTFNVCISTMDAELEFPLEQSAKGSELFDLVVRTLGVRETWYFGLQFEYPTGELAWLQFDKKVYKQNKTLKEPFALRLRAKFYPEDVAEELVQEITQHLFYLQVKDAILTMKTFCPPEASVLLASYAVQAKFGDYDKDL--HKPGFLQNEHLLPQTVIEQYQMTPAMWEERITSWYAEHHGLTRDEAEMEYLKLAQDLEMYGVSYFDITNKKGTAISLGIDCRGLNIYEKDNRLNPKTSFPWKEIKNISFHSRTFVIKSIDKQAPDFIFKTGNPRTNKVILELCLGNHELFKRRRKPDTMEIQQMKALAKEEKMRRQIERNKLLVEQQAREEAIRQKEELQARLQE 346
BLAST of FERM domain containing-1 vs. Ensembl Nematostella
Match: EDO38965 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBA4]) HSP 1 Score: 142.51 bits (358), Expect = 1.005e-36 Identity = 88/306 (28.76%), Postives = 151/306 (49.35%), Query Frame = 3
Query: 96 ESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELV--QEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQH-EISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSD--------------KNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDT 962
E L+F + L + V NL E +FGL + + G TWL+ ++++ ++ + PL F V+++ V N L+ + VT LF+LQ R I GSI C E+ LA Y Q YGDF ++ + +LP R +++H IS + E ++ YK + EAIV YL + Q L +GV+Y+ +K+K LG+ G+ +Y +K+ P F W++I+N+ + ++KF+++ D K+ V++ S + K + M++ H YL ++K +T
Sbjct: 10 ERRLDFLIQPRLMSCDLLDMVASHFNLHEKEYFGLSYAEEGGAQTWLRLDKRVLDHELPRHDPLILLFAVRFF---VPNILILKEPVTVELFFLQARALIFKGSIQCDTETVFELAGYVLQAVYGDFTS--VEATKQDLKKIAVLPTRTLKEHPSISYCE--EKVLTRYKLCVGQTKGEAIVRYLCIFQSLPTYGVHYYEVKDKGSIPWWLGLSPRGIGVYDHTDKIKPRKLFQWNQIENIYFRDRKFSLEIRDSYRYVQTFKIFHVHKDMMVHVWYASTSTLAKAMWSMAISQHQFYLDKKKVET 308
BLAST of FERM domain containing-1 vs. Ensembl Nematostella
Match: EDO36130 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJJ3]) HSP 1 Score: 112.464 bits (280), Expect = 2.212e-27 Identity = 79/242 (32.64%), Postives = 127/242 (52.48%), Query Frame = 3
Query: 135 GEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVI---EQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQD---NKLTPTIGFPWSEIKNVSYSNKKFTIKS 842
G L V + LNL E +FGLL+ D KG WL ++I Q G F+ VK+Y E ++L ++T+ + LQVR+DI+ + C + LL SY Q ++GD+ DP+ + N L V + HE+ +E I +++K H+ + EEA +YL+ A+ L M+GV+ ++ G E+L+GV G+ ++K D NK FPW ++ +SY + F++KS
Sbjct: 7 GIDLMVAVAEHLNLDEKEYFGLLY-DHKGEKYWLDPQKEIKKQLKGNL--PHFELAVKFY-EPYPSKLKHDMTRYMMVLQVRDDIICERLPCSFGAQALLGSYVVQSEFGDY------DPHE--HKGNYLAGLVFSPNQSHEL-----VERIKELHKEHRGLTPEEADTQYLEAARKLTMYGVDAHPARDGNGDEVLVGVSYAGVLVFKDDLRQNK------FPWPKVVYLSYKGRDFSVKS 225
BLAST of FERM domain containing-1 vs. Ensembl Nematostella
Match: EDO30224 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1E3]) HSP 1 Score: 112.849 bits (281), Expect = 8.043e-27 Identity = 78/296 (26.35%), Postives = 145/296 (48.99%), Query Frame = 3
Query: 72 ISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSK-GFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKF--TIKSSDKN----SSNFVFFTDHSRINKTILHMSMGNHDLY 938
+V+++ ++S+ E + T G+ LF+QV + L E +FGL + D K G WL+ +R I Q +GK PL F F VK+YPE L +++T+ F LQ+R D+L G I C LLASY Q + GD E + +++ P++ E + I ++ H M +A +YL + L ++G + + +G + + + A G+ +++ + ++ F W +I ++ + +KKF T+++ ++ S+ F R K + + + +H +
Sbjct: 9 CTVQVAGLDSDYECPIDKTTKGDHLFDQVCDHIGLAEKEYFGLRYIDEKDGQFNWLEGDRSIKRQ-MGKA-PLHFYFAVKFYPEN-PTTLREDITRYQFVLQLREDLLKGRIQCSNPIHALLASYVMQAELGDLHPE--EHEVAYLSDLKFFPKQPPELR--------QKIEAFHRKHVGMTPSDAEFQYLDNVRKLPLYGRDMYQAWGDEGQAVTIAISAWGVEVFQNNRQMH---RFVWPKIISIGFKSKKFSLTLRAPSEDDYYKSTTIYFKCGSQRAAKRVWKVCVEHHAFF 288
BLAST of FERM domain containing-1 vs. Ensembl Medaka
Match: ENSORLT00000040831.1 (radixin [Source:NCBI gene;Acc:101156778]) HSP 1 Score: 412.149 bits (1058), Expect = 5.297e-137 Identity = 214/401 (53.37%), Postives = 300/401 (74.81%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMEL-RL-KESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALE 1256
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K PLQFKF K++PE+V EL+QE+TQ+LF+LQV+ IL+ YCPPE++VLLASYA Q KYGD+ ++ I P ++ +D LLP+RV+EQH+++K +W + I ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ ++KL+P IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R+LA+ E R+ +E NE+ E ++ + EQ+ R ++ELEE + +RALE
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYTDSKGYVTWLKLNKKVTQQDVKKDNPLQFKFRAKFFPEDVSEELIQEITQKLFFLQVKEAILNDENYCPPETAVLLASYAVQAKYGDYNKD-IHKPG-YLASDRLLPQRVLEQHKLTKEQWEDRIQTWHEEHRGMLREDAMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHEDKLSPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHHKQ-----MERAQLENEKKKRELAEKEKDRIEREKNELMEKLRQ--------------IEEQTQRAQKELEE------QTRRALE 374 HSP 2 Score: 72.4034 bits (176), Expect = 6.082e-13 Identity = 41/88 (46.59%), Postives = 53/88 (60.23%), Query Frame = 3
Query: 1494 GSMEFVDD-----RREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
GS E D R EE R T N ++ QL++L+ +L E R K D +H EN R G DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 485 GSAELPSDGVTNHRSEEERVTEAQKNERVKKQLQALSSELAEARDDTKKTQNDMLHAENVRAGRDKYKTLRQIRQGNTKQRIDEFESM 572
BLAST of FERM domain containing-1 vs. Ensembl Medaka
Match: ENSORLT00000011512.2 (radixin [Source:NCBI gene;Acc:101156778]) HSP 1 Score: 412.149 bits (1058), Expect = 5.472e-137 Identity = 214/401 (53.37%), Postives = 300/401 (74.81%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMEL-RL-KESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALE 1256
M KPI+V+++T+++ELEF++ NTTG++LF+QVVKT+ LRE WFFGL + DSKG+ TWLK N+K+T QDV K PLQFKF K++PE+V EL+QE+TQ+LF+LQV+ IL+ YCPPE++VLLASYA Q KYGD+ ++ I P ++ +D LLP+RV+EQH+++K +W + I ++ H+ MLRE+A++EYLK+AQDLEM+GVNYF IKNKKG+EL LGVDALGL+IY+ ++KL+P IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTIE+QQMKAQA EE+ KQ + R +L E+ +R+LA+ E R+ +E NE+ E ++ + EQ+ R ++ELEE + +RALE
Sbjct: 1 MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYTDSKGYVTWLKLNKKVTQQDVKKDNPLQFKFRAKFFPEDVSEELIQEITQKLFFLQVKEAILNDENYCPPETAVLLASYAVQAKYGDYNKD-IHKPG-YLASDRLLPQRVLEQHKLTKEQWEDRIQTWHEEHRGMLREDAMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHEDKLSPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHHKQ-----MERAQLENEKKKRELAEKEKDRIEREKNELMEKLRQ--------------IEEQTQRAQKELEE------QTRRALE 374 HSP 2 Score: 72.4034 bits (176), Expect = 6.812e-13 Identity = 41/88 (46.59%), Postives = 53/88 (60.23%), Query Frame = 3
Query: 1494 GSMEFVDD-----RREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
GS E D R EE R T N ++ QL++L+ +L E R K D +H EN R G DK+KTLRQIRQGNTK+R+D FE++
Sbjct: 485 GSAELPSDGVTNHRSEEERVTEAQKNERVKKQLQALSSELAEARDDTKKTQNDMLHAENVRAGRDKYKTLRQIRQGNTKQRIDEFESI 572
BLAST of FERM domain containing-1 vs. Ensembl Medaka
Match: msna (moesin [Source:NCBI gene;Acc:101173881]) HSP 1 Score: 407.912 bits (1047), Expect = 2.832e-135 Identity = 177/302 (58.61%), Postives = 245/302 (81.13%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M K ISVK++T+++ELEF++ NTTG++LF+QVVKT+ LRE W+FGL ++D+KGF TWLK N+K+TAQDV K+ P+ FKF K++PE+V EL+Q+ TQRLF+LQV+ IL IYCPPE++VLLASYA Q K+ D+ +E+ ++N + LLP+RV++QH+++K +W E I ++ HK M+RE++++EYLK+AQDLEM+GVNYFNIKNKKG+EL LGVDALGL+IY+Q +K+TP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 MPKTISVKVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPMLFKFRAKFFPEDVSEELIQDATQRLFFLQVKEAILSDDIYCPPETAVLLASYAVQAKFADYNKEV--HTTGYLNGEQLLPQRVLDQHKLNKEQWEERIQVWHEEHKGMIREDSMMEYLKIAQDLEMYGVNYFNIKNKKGTELWLGVDALGLNIYEQTDKMTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 68.5514 bits (166), Expect = 1.059e-11 Identity = 37/76 (48.68%), Postives = 45/76 (59.21%), Query Frame = 3
Query: 1515 DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
DR EE R T N LQ L +L+ +L R K D IH EN + G DK+KTLRQIR GNTK+R+D FE +
Sbjct: 504 DRSEEERMTEAEKNERLQKHLLALSSELANARDETKKTVNDMIHAENMKAGRDKYKTLRQIRSGNTKQRIDEFECM 579
BLAST of FERM domain containing-1 vs. Ensembl Medaka
Match: msna (moesin [Source:NCBI gene;Acc:101173881]) HSP 1 Score: 405.986 bits (1042), Expect = 3.413e-134 Identity = 177/302 (58.61%), Postives = 245/302 (81.13%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTI 965
M K ISVK++T+++ELEF++ NTTG++LF+QVVKT+ LRE W+FGL ++D+KGF TWLK N+K+TAQDV K+ P+ FKF K++PE+V EL+Q+ TQRLF+LQV+ IL IYCPPE++VLLASYA Q K+ D+ +E+ ++N + LLP+RV++QH+++K +W E I ++ HK M+RE++++EYLK+AQDLEM+GVNYFNIKNKKG+EL LGVDALGL+IY+Q +K+TP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNH+LY++RRKPDTI
Sbjct: 1 MPKTISVKVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYQDTKGFSTWLKLNKKVTAQDVRKESPMLFKFRAKFFPEDVSEELIQDATQRLFFLQVKEAILSDDIYCPPETAVLLASYAVQAKFADYNKEV--HTTGYLNGEQLLPQRVLDQHKLNKEQWEERIQVWHEEHKGMIREDSMMEYLKIAQDLEMYGVNYFNIKNKKGTELWLGVDALGLNIYEQTDKMTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI 300 HSP 2 Score: 49.6766 bits (117), Expect = 9.182e-6 Identity = 29/62 (46.77%), Postives = 34/62 (54.84%), Query Frame = 3
Query: 1515 DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIR 1700
DR EE R T N LQ L +L+ +L R K D IH EN + G DK+KTLRQIR
Sbjct: 504 DRSEEERMTEAEKNERLQKHLLALSSELANARDETKKTVNDMIHAENMKAGRDKYKTLRQIR 565
BLAST of FERM domain containing-1 vs. Ensembl Medaka
Match: ENSORLT00000042394.1 (moesin-like [Source:NCBI gene;Acc:101173478]) HSP 1 Score: 402.519 bits (1033), Expect = 8.275e-134 Identity = 209/417 (50.12%), Postives = 300/417 (71.94%), Query Frame = 3
Query: 93 VESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIER---KLADMELRLKES-NEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQIS 1331
+++ELEF++ +TTG++LF+Q+VKT+ LRETWFFGL ++DSKGF TWLK N+++TAQDV K PL KF ++YPE+V EL+QE TQRLF+LQV+ IL+ IYCPPE++VLLASYA Q K+GD+R++ ++ + LLP+RV+EQH+++K +W E I K ++ HK MLRE+A++EYLK+AQDLEM+GVNYFNIKNKKGSEL LGVDALGL+IY + +K+TP IGFPWSEI+N+S+++KKF IK DK + +FVF+ RINK IL + MGNHDLY++RRKPDTIE+QQMKAQA EE+ +Q + + E+ +E E+ K+A + L E ++ E T+R + ++ E +S ++++ +E RL +++RA AK + E +K E + +++
Sbjct: 1 MDAELEFAILPSTTGKQLFDQIVKTIGLRETWFFGLQYQDSKGFSTWLKLNKRVTAQDVKKSNPLLIKFRARFYPEDVAEELIQEATQRLFFLQVKESILNDDIYCPPETAVLLASYAVQVKHGDYRKDY--HVQGYLTKERLLPQRVLEQHKLNKTQWEERIQKWHEEHKGMLREDAMLEYLKIAQDLEMYGVNYFNIKNKKGSELWLGVDALGLNIYDKKDKMTPKIGFPWSEIRNISFNDKKFVIKPIDKRAPDFVFYVPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKSKRQKERALLESEKKKREYAEKETEKIARETMELMERLRQIEEQTKR----AQDELEEQTRRALESEKERKIAQEEAERLDKDRRAAVEAKETLLHNSETQIKNQESLATELA 411
BLAST of FERM domain containing-1 vs. Planmine SMEST
Match: SMESG000070273.1 (SMESG000070273.1) HSP 1 Score: 998.423 bits (2580), Expect = 0.000e+0 Identity = 561/561 (100.00%), Postives = 561/561 (100.00%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKNIEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVTLGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIEMQQMKAQAEEERKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQLEEYERKIRELEELLEQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKNIEVEHGSEELRQRQEELERLRAEREELEAKASMLEEAAKAKEKSKEEDVTLGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL
Sbjct: 1 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIEMQQMKAQAEEERKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQLEEYERKIRELEELLEQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKNIEVEHGSEELRQRQEELERLRAEREELEAKASMLEEAAKAKEKSKEEDVTLGSMEFVDDRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 561
BLAST of FERM domain containing-1 vs. Planmine SMEST
Match: SMESG000056380.1 (SMESG000056380.1) HSP 1 Score: 638.262 bits (1645), Expect = 0.000e+0 Identity = 367/562 (65.30%), Postives = 458/562 (81.49%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPNNFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKNIEVEHGSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDVTLGSMEFVD-DRREESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
MSK I++K+ST++SELEFSVA+NTTG++LF+QVV+TLN+RE W+FGL + DSKG +WLK NRK+T+QDVGK YPL+ +FCVKYYPE+V EL+QE TQRLFYLQVR DIL G IYCPPE+ VLLASYACQCKY DF + L+ + FI D LLP+++++QH ++ +WI+ IV MYK+HKDMLRE++++EYLK+AQDL+M+GVNYF I NKKG+EL LG+DALGL+IY +DNKLT IGFPWSEI+NVSYSNKKF+IKS+DKNSSNFVF T HSRINK IL++SMGNHDLYL+RRK +TIEMQQM+AQAEE++K K + KDK+ +ERLAKE +ERKLA++EL LK SNE NE +Q+QLEEYERKIRELE LLE+SN+QK++LE MH +LA N RALE A+ ED E+LL+ENE IQ +I KN EV+ + EL +RQ ELE+LR EREELE KA LEE A KE ++EE + D DRREE+R T +S N +LQ+QLK LA +L E+R+ +K++ D IH ENQR G DKF+TLRQIRQGNTKKRVD FE+L
Sbjct: 1 MSKTIAIKVSTIDSELEFSVASNTTGKQLFDQVVRTLNIREIWWFGLKYIDSKGLTSWLKLNRKVTSQDVGKIYPLKLQFCVKYYPEDVGVELIQEATQRLFYLQVRQDILSGDIYCPPETCVLLASYACQCKYLDFNDSLVANKEEFIYKDRLLPQKIVDQHGMTNEQWIDKIVMMYKSHKDMLREDSMLEYLKIAQDLDMYGVNYFEITNKKGTELYLGIDALGLNIYNKDNKLTAKIGFPWSEIRNVSYSNKKFSIKSTDKNSSNFVFMTKHSRINKAILNLSMGNHDLYLRRRKNETIEMQQMRAQAEEDKKAKLDSKDKVNQERLAKEMVERKLAELELILKASNEKNEESQKQLEEYERKIRELETLLEESNKQKQDLEFMHEKLAANNRALEEAQKTVSEDYEKLLQENELIQSEIHLKNSEVQQSAIELSERQAELEKLRMEREELELKARQLEEIAIEKENNREEAHNFELLATGDDDRREENRTTTLSGNKDLQDQLKCLANELEERRLESKLDQTDLIHRENQRQGRDKFQTLRQIRQGNTKKRVDEFESL 562
BLAST of FERM domain containing-1 vs. Planmine SMEST
Match: SMESG000068090.1 (SMESG000068090.1) HSP 1 Score: 380.563 bits (976), Expect = 7.681e-125 Identity = 193/431 (44.78%), Postives = 300/431 (69.61%), Query Frame = 3
Query: 60 MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKDSKGFPTWLKYNRKITAQDVGKQYPLQFKFCVKYYPEEVENELVQEVTQRLFYLQVRNDILDGSIYCPPESSVLLASYACQCKYGDFREELIDDPN----NFINTDNLLPERVIEQHEISKAKWIETIVKMYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIKSSDKNSSNFVFFTDHSRINKTILHMSMGNHDLYLKRRKPDTIXXXXXXXXXXXXRKTKQNYKDKITRERLAKEEIERKLADMELRLKESNEVNEGTQRQXXXXXXXXXXXXXXXXQSNRQKRELEEMHARLAENKRALEHAKANADEDRERLLKENEQIQLQISKKN 1340
M K I+V ++TV++EL+FS+ +N G+ LF+Q++KT+ LRETW+FGLL+ D KG WL +K++ +V + ++F+F +K+YPE+V EL+QE+T + FYLQVR IL I+CPPE ++LLASYACQ K+GD+ DP+ F++ + +LP R++ QH+ S +W IVK Y ++ MLR EA++EYLK+AQDLEM+GV+YF IKNKKGS+L +G+DALGL+IYK +KLTP +GFPW EI+N+S+ +K+F IKS DK + +FVFF + R+NKTIL + GNH+L+++RR D+I++QQMK QA+E++ K+N K+++ RE+LA+E E++L +E +LK+ + + T + L + ++E LE +Q++ LE+ + + K+ LE + + +L EN +IQ + ++N
Sbjct: 1 MPKNINVNVTTVDAELQFSIQSNAIGKTLFDQIIKTIGLRETWYFGLLYIDVKGNLCWLNLEKKVSHINVLSKTEMEFQFRIKFYPEDVSEELIQEITIKFFYLQVRESILGSDIFCPPEPALLLASYACQVKFGDY------DPSVQKPGFLSDERILPPRILNQHKWSNQQWESKIVKWYSEYRGMLRVEAMLEYLKIAQDLEMYGVSYFEIKNKKGSQLYIGIDALGLNIYKFKDKLTPQVGFPWGEIRNISFKDKRFVIKSIDKKAPDFVFFVNKLRVNKTILALCAGNHELFVRRRNEDSIDVQQMKTQAQEDKINKKNEKERLFREKLAREAAEKRLVSIEKKLKQETQEHAETNKTLLTVRQSFSLIQEQLEAECKQRKALEDRQQEILKEKKLLEERNLEETDCYKNILTENSEIQRVLDEQN 425 HSP 2 Score: 71.2478 bits (173), Expect = 9.743e-13 Identity = 36/72 (50.00%), Postives = 50/72 (69.44%), Query Frame = 3
Query: 1527 ESRQTNISSNIELQNQLKSLAQDLNEKRVVNKMEGIDHIHNENQRLGLDKFKTLRQIRQGNTKKRVDRFEAL 1742
E+R+T I ++ +L N+L L ++L E R + ID IH N+ GLDKF+TLR IRQGNTKKR+D FE++
Sbjct: 495 ENRRTIIEADEDLHNKLSDLGEELKEARNSKGFDEIDTIHENNKAKGLDKFQTLRLIRQGNTKKRIDEFESM 566
BLAST of FERM domain containing-1 vs. Planmine SMEST
Match: SMESG000016264.1 (SMESG000016264.1) HSP 1 Score: 169.088 bits (427), Expect = 4.875e-44 Identity = 116/331 (35.05%), Postives = 173/331 (52.27%), Query Frame = 3
Query: 42 KLLSLNMSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGL--LFKDSKG---FPTWLKYNRKITAQDVGKQYPLQFKFCV--KYYPEEVENELVQEVTQRLFYLQVRN----------------------------------------DILDGSIY---CPPESSVLLASYACQCKYGDFRE-ELIDDPNN-FINTDNLLPERVIEQHEISKAKWIETIVK-MYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIK--SSDKNSSNFV 869
K +S + SK + +K++T +++LEF ++ TTGE LFE V ++ L ET++FGL + DS G WLK ++I+AQ + + KF + K++PE++E EL+Q +T+ LFYL V+N DI DGS P + ++LLAS + Q +YGD E E DD + F+ L + ++ + VK YK+HK M RE+A + YLK+A +FG++YF I +K GV A G+SIY+ DNK+ P F W IKNVSY ++KFTIK +SD NS ++
Sbjct: 2 KWVSKSNSKALHIKVNTYDNDLEFHLSHKTTGESLFEMVCASIGLHETYYFGLENYYIDSNGQIELTKWLKLEKRISAQKLNHSPLKEIKFLLHPKFFPEDIERELIQPMTRHLFYLDVKNALIRQSVVNNSNHFSATTSECTNKADCTLQNGDKSSDGQLDIDDGSSSRSNPPSDVAILLASLSAQAEYGDLSETECQDDEDRMFLPGRLLRLLPSGLLMQCQLSQEVTRRVKQCYKSHKGMSREDAELAYLKVAHLYRLFGIDYFMISDKMNCASWFGVSASGISIYQLDNKIQPLQSFSWKIIKNVSYKDRKFTIKLTTSDLNSPTYL 332
BLAST of FERM domain containing-1 vs. Planmine SMEST
Match: SMESG000016264.1 (SMESG000016264.1) HSP 1 Score: 168.703 bits (426), Expect = 5.231e-44 Identity = 116/331 (35.05%), Postives = 173/331 (52.27%), Query Frame = 3
Query: 42 KLLSLNMSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGL--LFKDSKG---FPTWLKYNRKITAQDVGKQYPLQFKFCV--KYYPEEVENELVQEVTQRLFYLQVRN----------------------------------------DILDGSIY---CPPESSVLLASYACQCKYGDFRE-ELIDDPNN-FINTDNLLPERVIEQHEISKAKWIETIVK-MYKNHKDMLREEAIVEYLKLAQDLEMFGVNYFNIKNKKGSELLLGVDALGLSIYKQDNKLTPTIGFPWSEIKNVSYSNKKFTIK--SSDKNSSNFV 869
K +S + SK + +K++T +++LEF ++ TTGE LFE V ++ L ET++FGL + DS G WLK ++I+AQ + + KF + K++PE++E EL+Q +T+ LFYL V+N DI DGS P + ++LLAS + Q +YGD E E DD + F+ L + ++ + VK YK+HK M RE+A + YLK+A +FG++YF I +K GV A G+SIY+ DNK+ P F W IKNVSY ++KFTIK +SD NS ++
Sbjct: 2 KWVSKSNSKALHIKVNTYDNDLEFHLSHKTTGESLFEMVCASIGLHETYYFGLENYYIDSNGQIELTKWLKLEKRISAQKLNHSPLKEIKFLLHPKFFPEDIERELIQPMTRHLFYLDVKNALIRQSVVNNSNHFSATTSECTNKADCTLQNGDKSSDGQLDIDDGSSSRSNPPSDVAILLASLSAQAEYGDLSETECQDDEDRMFLPGRLLRLLPSGLLMQCQLSQEVTRRVKQCYKSHKGMSREDAELAYLKVAHLYRLFGIDYFMISDKMNCASWFGVSASGISIYQLDNKIQPLQSFSWKIIKNVSYKDRKFTIKLTTSDLNSPTYL 332 The following BLAST results are available for this feature:
BLAST of FERM domain containing-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of FERM domain containing-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of FERM domain containing-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of FERM domain containing-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of FERM domain containing-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of FERM domain containing-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of FERM domain containing-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of FERM domain containing-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of FERM domain containing-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of FERM domain containing-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of FERM domain containing-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of FERM domain containing-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of FERM domain containing-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of FERM domain containing-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30022344 ID=SMED30022344|Name=FERM domain containing-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1843bpback to top protein sequence of SMED30022344-orf-1 >SMED30022344-orf-1 ID=SMED30022344-orf-1|Name=SMED30022344-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=562bp MSKPISVKISTVESELEFSVAANTTGEKLFEQVVKTLNLRETWFFGLLFKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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