Dynamin-type G domain-containing protein

Overview


Name	Dynamin-type G domain-containing protein
Smed ID	SMED30022278
Length (bp)	2015

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dynamin-type G domain-containing protein (SMED30022278) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dynamin-type G domain-containing protein (SMED30022278) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30022278

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30022278	h1SMcG0019634	SmedASXL_016543	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
anterior region of the whole animal	SMED30022278	h1SMcG0019634	SmedASXL_016543	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
pigment cell	SMED30022278	h1SMcG0019634	SmedASXL_016543	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
nervous system	SMED30022278	h1SMcG0019634	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30022278	h1SMcG0019634	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30022278	h1SMcG0019634	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30022278	h1SMcG0019634	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30022278	h1SMcG0019634	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30022278	h1SMcG0019634	Contig45482	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30022278	h1SMcG0019634	Contig45482	newmark_ests	PMID:29674431 Fincher et al., 2018
dorsal-ventral muscle cell	SMED30022278	h1SMcG0019634	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:30471994 Scimone et al., 2018
epidermis	SMED30022278	h1SMcG0019634	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262])

HSP 1 Score: 99.3673 bits (246), Expect = 9.214e-22
Identity = 73/273 (26.74%), Postives = 134/273 (49.08%), Query Frame = 2

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKS----SKTAKKRFDEFTRFEYNLKKYIS 1039
            K  +I E ++R  +K+  FG+ S GKS ++NAML D    SG  H T+ F+ V+ ++ D +Y +     ++        +     +  D+K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + ++ + E C  FL ++L ++   E   RI+F+S+ E+   R +    + +S    ++    R  EF  FE   ++ IS
Sbjct:   63 KLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECIS 329

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN2 (mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877])

HSP 1 Score: 101.293 bits (251), Expect = 1.779e-21
Identity = 71/274 (25.91%), Postives = 136/274 (49.64%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFD----EFTRFEYNLKKYIS 1039
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++               +++ +  + + +++  +  +K   A   + V        LLK  + ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ ++ + E C+ FL D L ++ + +  +RI+F+S+ E+   RI+    + +      + F     EF  FE   ++ IS
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHE-----AFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECIS 350

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Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFD----EFTRFEYNLKKYIS 1039
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++               +++ +  + + +++  +  +K   A   + V        LLK  + ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ ++ + E C+ FL D L ++ + +  +RI+F+S+ E+   RI+    + +      + F     EF  FE   ++ IS
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHE-----AFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECIS 350

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262])

HSP 1 Score: 99.3673 bits (246), Expect = 5.889e-21
Identity = 73/273 (26.74%), Postives = 134/273 (49.08%), Query Frame = 2

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKS----SKTAKKRFDEFTRFEYNLKKYIS 1039
            K  +I E ++R  +K+  FG+ S GKS ++NAML D    SG  H T+ F+ V+ ++ D +Y +     ++        +     +  D+K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + ++ + E C  FL ++L ++   E   RI+F+S+ E+   R +    + +S    ++    R  EF  FE   ++ IS
Sbjct:   63 KLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECIS 329

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262])

HSP 1 Score: 99.3673 bits (246), Expect = 5.889e-21
Identity = 73/273 (26.74%), Postives = 134/273 (49.08%), Query Frame = 2

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKS----SKTAKKRFDEFTRFEYNLKKYIS 1039
            K  +I E ++R  +K+  FG+ S GKS ++NAML D    SG  H T+ F+ V+ ++ D +Y +     ++        +     +  D+K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + ++ + E C  FL ++L ++   E   RI+F+S+ E+   R +    + +S    ++    R  EF  FE   ++ IS
Sbjct:   63 KLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECIS 329

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
Match: fzo-1 (Transmembrane GTPase fzo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q23424])

HSP 1 Score: 91.2781 bits (225), Expect = 9.419e-19
Identity = 79/319 (24.76%), Postives = 142/319 (44.51%), Query Frame = 2

Query:  224 KLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKG--NKATANETIEVSICMDDETL---------------LKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKS--SKTAKKRFDEFTRFEYNLKKYISAPQ-----DNKTRRYTEEIKKLQTYL 1102
            +++ I    + I +   RD +K+  FG+ S GKS  +NAML +     G  HTT  F+ V+ SE +                 +  +  ++I   + G    A ++E  ++     D  L               L+  + I+D PG     +    I K+  +AD+F+ V N    LT  ++ FF       +KP+VFI+ N+WD S  + E    + K+ +       + +L++  + E+++RI+F+SS E+ + R++    + K+  ++    R  EF  FE + +  IS        +   RR  E I K++  L
Sbjct:   81 EIEAIGDSIKTIMDTFQRDNMKVVFFGRTSNGKSTTINAMLHEKVLPQGMGHTTCCFLQVEGSEGE-------------VGHLQLDDNPQKIDMKMLGKIGHALSDENSDLPAMGQDSLLKVFHPKKSESGECRLLQNDVVILDSPGVDLSPEFDSWIDKHCLDADVFVLVSNAESTLTQAEKNFFLRVAKKLSKPNVFILNNRWDASAAETENIEDVKKQHLTRFRQFLVDELEVCSEREVNDRIFFVSSREVLESRLKARGLVQKAYQAEGHGTRALEFQNFERHFEHCISRSAIHTKFEAHNRRAHEMIGKMRLNL 386

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070910)

HSP 1 Score: 110.923 bits (276), Expect = 6.908e-25
Identity = 91/336 (27.08%), Postives = 165/336 (49.11%), Query Frame = 2

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSED-DSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIE----NDDSLIKSSKTAKKRFDEFTRFEYNLKKYIS-APQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKG 1225
            K   I E + RD +K+  FG+ S GKS ++NAML +    SG  HTT+ F  V+ S   ++Y +     ++           I++++  +   K   +  + +    +  +LL+  +  VD PG    + + D I  +   AD+F+ VLN    +T  ++ FF       +KP++FI+ N+WD S N+  E  +  K +  E C  FL ++L +  ++E +ER++F+S+ E  Q RIE    N   +   ++  + R+ EF  FE   ++ IS +    K ++++   K +      + K   +NI     Y  I+ +R L +D K+   E +++G
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVV------NIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEP-ECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKGNPPHMGAIAEGFQIRYFEFQDFERKFEECISQSAVKTKFQQHSSRGKSVS----GDMKSMLDNI-----YERITIFRNLKQDQKNLLTE-RIQG 443

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070909)

HSP 1 Score: 110.923 bits (276), Expect = 6.908e-25
Identity = 91/336 (27.08%), Postives = 165/336 (49.11%), Query Frame = 2

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSED-DSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIE----NDDSLIKSSKTAKKRFDEFTRFEYNLKKYIS-APQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKG 1225
            K   I E + RD +K+  FG+ S GKS ++NAML +    SG  HTT+ F  V+ S   ++Y +     ++           I++++  +   K   +  + +    +  +LL+  +  VD PG    + + D I  +   AD+F+ VLN    +T  ++ FF       +KP++FI+ N+WD S N+  E  +  K +  E C  FL ++L +  ++E +ER++F+S+ E  Q RIE    N   +   ++  + R+ EF  FE   ++ IS +    K ++++   K +      + K   +NI     Y  I+ +R L +D K+   E +++G
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVV------NIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEP-ECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKGNPPHMGAIAEGFQIRYFEFQDFERKFEECISQSAVKTKFQQHSSRGKSVS----GDMKSMLDNI-----YERITIFRNLKQDQKNLLTE-RIQG 443

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0343373)

HSP 1 Score: 110.538 bits (275), Expect = 1.077e-24
Identity = 92/339 (27.14%), Postives = 169/339 (49.85%), Query Frame = 2

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSE-DDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDE-ESTQMSKEKIN--EECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIE----NDDSLIKSSKTAKKRFDEFTRFEYNLKKYIS-APQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKG 1225
            K   I E + RD +K+  FG+ S GKS ++NAML +    SG  HTT+ F  V+ S   ++Y +     ++           I++++  +   K   +  + +    +  +LL+  +  VD PG    + + D I  +   AD+F+ VLN    +T  ++ FF       +KP++FI+ N+WD S N+ E + ++++K K    E C  FL ++L +  ++E +ER++F+S+ E  Q RIE    N   +   ++  + R+ EF  FE   ++ IS +    K ++++   K +      + K   +NI     Y  I+ +R L +D K+   E +++G
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVV------NIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKGNPPHMGAIAEGFQIRYFEFQDFERKFEECISQSAVKTKFQQHSSRGKSVS----GDMKSMLDNI-----YERITIFRNLKQDQKNLLTE-RIQG 447

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: fzo (gene:FBgn0011596 transcript:FBtr0084399)

HSP 1 Score: 109.768 bits (273), Expect = 1.462e-24
Identity = 73/273 (26.74%), Postives = 132/273 (48.35%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFV-----------HVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMK-KEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFDEFTRFE 1015
            S+ E I + ++RD +K+  FG+ S GKS ++NA+L +    S   HTTS F            HVK  ++D +   +                + +++          +  ++V++  +  ++L   + ++D PG    +Q+ DC+     +AD+FI VLN    ++  +R FFK      ++P++FI+ N+WD++ + + E  Q  K++  E C   L D L +    +E  ERIY +S+ E    R   +  +   S   ++R+ EF RFE
Sbjct:   73 SRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQEDEHMELSA---------------LSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIR---NGQITNPSGQTQQRYQEFLRFE 327

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 97.8265 bits (242), Expect = 1.128e-21
Identity = 74/275 (26.91%), Postives = 141/275 (51.27%), Query Frame = 2

Query:  224 KLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKK----RFDEFTRFE 1015
            +LD IES   K  +I E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ +++D             +++ K I+ + +++  +  +++  A   ++V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S  + E    + K+   + C  FL ++L ++ + +   RI+F+S+ E+   R++    + ++     +    R  EF  FE
Sbjct:   54 QLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDED-----KAFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQH-TDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQNFE 322

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 100.523 bits (249), Expect = 1.561e-21
Identity = 76/283 (26.86%), Postives = 146/283 (51.59%), Query Frame = 2

Query:  224 KLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            +LD IES   K  +I E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ +++D             +++ K I+ + +++  +  +++  A   ++V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S  + E    + K+   + C  FL ++L ++ + +   RI+F+S+ E+   R++    + ++        + R  EF  FE + ++ IS
Sbjct:   54 QLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDK-----AFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQH-TDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQNFERSFEECIS 330

[Close]

Query:  224 KLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            +LD IES   K  +I E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ +++D             +++ K I+ + +++  +  +++  A   ++V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S  + E    + K+   + C  FL ++L ++ + +   RI+F+S+ E+   R++    + ++        + R  EF  FE + ++ IS
Sbjct:   54 QLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDK-----AFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQH-TDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQNFERSFEECIS 330

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44])

HSP 1 Score: 100.138 bits (248), Expect = 2.197e-21
Identity = 73/274 (26.64%), Postives = 134/274 (48.91%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSE-DDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFD----EFTRFEYNLKKYIS 1039
            SK   I E ++R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++ ++S+ +     +R        +        D+      A   + V        LL+  + +VD PG    +++   I K   +AD+F+ V N    L   ++ FF    +  + P++FI+ N+WD S N+ E   ++ ++ ++  C+ FL D L ++ +    +RI+F+S+ E+ Q R++    + ++     + F     EF  FE   ++ IS
Sbjct:   83 SKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNESFLLTEGSDERKSVKTVNQLAHALHQDEDLD-----AGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASANEPEYMEEVRRQHMD-RCTSFLVDELRVVDRSHAGDRIFFVSAKEVLQARVQKAQGMPEAGGALAEGFQARMFEFQNFERRFEECIS 350

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 95.9005 bits (237), Expect = 4.963e-21
Identity = 74/271 (27.31%), Postives = 140/271 (51.66%), Query Frame = 2

Query:  224 KLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIE--NDDSLIKSSKTAKKRFDEFTR 1009
            +LD IES   K  +I E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ +++D             +++ K I+ + +++  +  +++  A   ++V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S  + E    + K+   + C  FL ++L ++ + +   RI+F+S+ E+   R++     +L +  +   K F  F R
Sbjct:   54 QLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDK-----AFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQH-TDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGGALAEGFQDRLKEFQNFER 318

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 101.679 bits (252), Expect = 1.207e-21
Identity = 75/274 (27.37%), Postives = 134/274 (48.91%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKK----RFDEFTRFEYNLKKYIS 1039
            +K   I E + R  +K+  FG+ S GKS ++N+ML D    SG  HTT+ F+ V+ +E D +Y +     ++        +     +  D+      A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K+ + E C  FL D L ++   E  +RI+F+S+ E+   R+     + ++     +    RF EF +FE   ++ IS
Sbjct:   81 TKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLG-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHM-ERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFEKLFEECIS 348

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 101.293 bits (251), Expect = 1.289e-21
Identity = 75/274 (27.37%), Postives = 134/274 (48.91%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKK----RFDEFTRFEYNLKKYIS 1039
            +K   I E + R  +K+  FG+ S GKS ++N+ML D    SG  HTT+ F+ V+ +E D +Y +     ++        +     +  D+      A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K+ + E C  FL D L ++   E  +RI+F+S+ E+   R+     + ++     +    RF EF +FE   ++ IS
Sbjct:   63 TKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLG-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHM-ERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFEKLFEECIS 330

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 101.293 bits (251), Expect = 1.472e-21
Identity = 75/274 (27.37%), Postives = 134/274 (48.91%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKK----RFDEFTRFEYNLKKYIS 1039
            +K   I E + R  +K+  FG+ S GKS ++N+ML D    SG  HTT+ F+ V+ +E D +Y +     ++        +     +  D+      A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K+ + E C  FL D L ++   E  +RI+F+S+ E+   R+     + ++     +    RF EF +FE   ++ IS
Sbjct:   63 TKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLG-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHM-ERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFEKLFEECIS 330

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 101.293 bits (251), Expect = 1.563e-21
Identity = 75/274 (27.37%), Postives = 134/274 (48.91%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKK----RFDEFTRFEYNLKKYIS 1039
            +K   I E + R  +K+  FG+ S GKS ++N+ML D    SG  HTT+ F+ V+ +E D +Y +     ++        +     +  D+      A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K+ + E C  FL D L ++   E  +RI+F+S+ E+   R+     + ++     +    RF EF +FE   ++ IS
Sbjct:   73 TKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLG-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHM-ERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFEKLFEECIS 340

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 101.293 bits (251), Expect = 1.603e-21
Identity = 75/274 (27.37%), Postives = 134/274 (48.91%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKK----RFDEFTRFEYNLKKYIS 1039
            +K   I E + R  +K+  FG+ S GKS ++N+ML D    SG  HTT+ F+ V+ +E D +Y +     ++        +     +  D+      A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K+ + E C  FL D L ++   E  +RI+F+S+ E+   R+     + ++     +    RF EF +FE   ++ IS
Sbjct:   78 TKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDKAYLMTEGSEEKKSVKTVNQLAHALHMDKDLG-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHM-ERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFEKLFEECIS 345

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn1 (mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664])

HSP 1 Score: 102.064 bits (253), Expect = 6.461e-22
Identity = 74/273 (27.11%), Postives = 132/273 (48.35%), Query Frame = 2

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            K  VI E ++R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++ D +Y +     ++        +     +  D+K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + ++ + E C  FL ++L ++   E   RI+F+S+ E+   R      + +         + R  EF  FE   ++ IS
Sbjct:   63 KLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECIS 329

[Close]

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            K  VI E ++R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++ D +Y +     ++        +     +  D+K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + ++ + E C  FL ++L ++   E   RI+F+S+ E+   R      + +         + R  EF  FE   ++ IS
Sbjct:   63 KLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECIS 329

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230])

HSP 1 Score: 99.3673 bits (246), Expect = 4.846e-21
Identity = 71/273 (26.01%), Postives = 130/273 (47.62%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFD----EFTRFEYNLKKYIS 1039
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V  +  D +               K + ++       +  +  A   + V        LLK  + ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ ++ + E C+ FL D L ++ + +  +RI+F+S+ E+   R++    + +      + F     EF  FE   ++ IS
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGT--DGHEAFLLTEGSEEKKSVKTVNQLAHALH--QDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECIS 350

[Close]

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFD----EFTRFEYNLKKYIS 1039
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V  +  D +               K + ++       +  +  A   + V        LLK  + ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ ++ + E C+ FL D L ++ + +  +RI+F+S+ E+   R++    + +      + F     EF  FE   ++ IS
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGT--DGHEAFLLTEGSEEKKSVKTVNQLAHALH--QDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECIS 350

[Close]

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFD----EFTRFEYNLKKYIS 1039
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V  +  D +               K + ++       +  +  A   + V        LLK  + ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ ++ + E C+ FL D L ++ + +  +RI+F+S+ E+   R++    + +      + F     EF  FE   ++ IS
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGT--DGHEAFLLTEGSEEKKSVKTVNQLAHALH--QDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECIS 350

[Close]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7YU24|MARF_DROME (Transmembrane GTPase Marf OS=Drosophila melanogaster OX=7227 GN=Marf PE=1 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 6.924e-24
Identity = 91/336 (27.08%), Postives = 165/336 (49.11%), Query Frame = 2

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSED-DSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIE----NDDSLIKSSKTAKKRFDEFTRFEYNLKKYIS-APQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKG 1225
            K   I E + RD +K+  FG+ S GKS ++NAML +    SG  HTT+ F  V+ S   ++Y +     ++           I++++  +   K   +  + +    +  +LL+  +  VD PG    + + D I  +   AD+F+ VLN    +T  ++ FF       +KP++FI+ N+WD S N+  E  +  K +  E C  FL ++L +  ++E +ER++F+S+ E  Q RIE    N   +   ++  + R+ EF  FE   ++ IS +    K ++++   K +      + K   +NI     Y  I+ +R L +D K+   E +++G
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVV------NIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEP-ECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKGNPPHMGAIAEGFQIRYFEFQDFERKFEECISQSAVKTKFQQHSSRGKSVS----GDMKSMLDNI-----YERITIFRNLKQDQKNLLTE-RIQG 443

[Close]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|O18412|FZO_DROME (Transmembrane GTPase fzo OS=Drosophila melanogaster OX=7227 GN=fzo PE=1 SV=2)

HSP 1 Score: 109.768 bits (273), Expect = 1.466e-23
Identity = 73/273 (26.74%), Postives = 132/273 (48.35%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFV-----------HVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMK-KEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFDEFTRFE 1015
            S+ E I + ++RD +K+  FG+ S GKS ++NA+L +    S   HTTS F            HVK  ++D +   +                + +++          +  ++V++  +  ++L   + ++D PG    +Q+ DC+     +AD+FI VLN    ++  +R FFK      ++P++FI+ N+WD++ + + E  Q  K++  E C   L D L +    +E  ERIY +S+ E    R   +  +   S   ++R+ EF RFE
Sbjct:   73 SRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQEDEHMELSA---------------LSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIR---NGQITNPSGQTQQRYQEFLRFE 327

[Close]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8R4Z9|MFN1_RAT (Mitofusin-1 OS=Rattus norvegicus OX=10116 GN=Mfn1 PE=1 SV=1)

HSP 1 Score: 102.834 bits (255), Expect = 2.722e-21
Identity = 74/273 (27.11%), Postives = 133/273 (48.72%), Query Frame = 2

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            K  VI E ++R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++ D +Y +     ++        +     +  D+K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + ++ + E C  FL ++L ++   E   RI+F+S+ E+   R+     + +         + R  EF  FE   ++ IS
Sbjct:   63 KLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVSPLEARNRIFFVSAKEVLNSRMNKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECIS 329

[Close]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8R500|MFN2_RAT (Mitofusin-2 OS=Rattus norvegicus OX=10116 GN=Mfn2 PE=1 SV=1)

HSP 1 Score: 102.834 bits (255), Expect = 2.745e-21
Identity = 72/273 (26.37%), Postives = 131/273 (47.99%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFD----EFTRFEYNLKKYIS 1039
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V  +  D +               K + ++       +  +  A   + V        LLK G+ ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ ++ + E C+ FL D L ++ + +  +RI+F+S+ E+   R++    + +      + F     EF  FE   ++ IS
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGT--DGHEAFLLTEGSEEKKSVKTVNQLAHALH--QDEQLHAGSLVSVMWPNSKCPLLKDGLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECIS 350

[Close]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q811U4|MFN1_MOUSE (Mitofusin-1 OS=Mus musculus OX=10090 GN=Mfn1 PE=1 SV=3)

HSP 1 Score: 102.064 bits (253), Expect = 4.519e-21
Identity = 74/273 (27.11%), Postives = 132/273 (48.35%), Query Frame = 2

Query:  245 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            K  VI E ++R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++ D +Y +     ++        +     +  D+K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + ++ + E C  FL ++L ++   E   RI+F+S+ E+   R      + +         + R  EF  FE   ++ IS
Sbjct:   63 KLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECIS 329

[Close]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A5E4MV73 (Dynamin superfamily,Fzo/mitofusin HR2 domain,P-loop containing nucleoside triphosphate hydrolase,Dynamin OS=Cinara cedri OX=506608 GN=CINCED_3A012836 PE=3 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 9.169e-25
Identity = 99/350 (28.29%), Postives = 171/350 (48.86%), Query Frame = 2

Query:  239 ESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSED-DSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKA-TANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLN-------YALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKK----RFDEFTRFEYNLK----------KYISAPQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLIS-------KYRKLIEDLKD 1198
            ESK   I E + RD +K+  FG+ S GKS ++NAMLGD    +G  HTT+ F+ V+ S+  D+Y           +++ + +E I  ++  +   K     E + V    D   LL+  + +VD PG      + D I  +  +AD+F+ V N       Y +  + + F K     S KP++FI+ N+WD S N+ E   Q+ K+ +       +++L +   +E S RI+F+S+ E+ Q R++    L  +S    +    R+ EF  FE+  +          K+++  Q  K    ++E K L+    K+C+  K+  + E+  SLIS       K  ++++D+KD
Sbjct:   56 ESKVRGICEVLTRDHMKVAFFGRTSNGKSTVVNAMLGDKVLPTGIGHTTNCFLQVEGSQSGDAY------LVIEGSNEKQNVESISHLAHALNHEKQLNEKELVHVYWPKDRCVLLRDDVALVDSPGVDVTPHLDDWIDNHCIDADVFVLVANAESXLYVYQINGEKKFFHKVSSKLS-KPNIFILNNRWDASANEPEFLDQVRKQHMERATDFLMKELKVCTADEASTRIFFISAKEVLQARVQERKGLALNSGALAEGFSTRYMEFKEFEHRFEECISKSAIKTKFLNHSQQGKHLIKSQEQKNLKLDEIKKCQ--KKLNYTEQ--SLISITNDMKMKIGQMVDDVKD 394

[Close]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A1A9X2I7 (Dynamin-type G domain-containing protein OS=Glossina brevipalpis OX=37001 PE=3 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 4.511e-24
Identity = 86/292 (29.45%), Postives = 155/292 (53.08%), Query Frame = 2

Query:  257 ITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSE-DDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIE----NDDSLIKSSKTAKKRFDEFTRFEYNLKKYIS-APQDNKTRRYTEEIKKLQTYLC 1105
            I E + RD +K+  FG+ S GKS ++NAML +    +G  HTT+ F  V+  +  ++Y IK    ++         ++I++++  +   K + N  I +    D  +LL+ G+  +D PG    + + D I  +   AD+F+ VLN    +T  ++ FF       +KP++FI+ N+WD S N ++E  +  K +  E C  FL ++L +  +EE +ER++F+S+ E+ Q RIE    N  S    ++  + R+ EF  FE   ++ IS +  + K ++++   K L + +C
Sbjct:  111 IREVLARDHMKVAFFGRTSNGKSSVINAMLREKILPNGIGHTTNCFCQVEGCDGSEAYLIKEGSDEKLNV------KDIKQLANALSQEKLSENSLIRIFWPRDRCSLLRDGVVFMDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHKVSQKLSKPNIFILNNRWDASAN-EQEFQESVKSQHTERCVDFLTKELKITNEEEAAERVFFVSAREVVQARIEKAKGNSPSSGAIAEGFQIRYFEFQDFERKFEECISKSAVETKFKKHSFRGKALSSDMC 395

[Close]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A0D2X0Q9 (Transmembrane GTPase Marf OS=Capsaspora owczarzaki (strain ATCC 30864) OX=595528 GN=CAOG_000950 PE=3 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 5.727e-24
Identity = 116/414 (28.02%), Postives = 185/414 (44.69%), Query Frame = 2

Query:  191 KVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANET-------IEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFDEFTRFEYNLKKYISAPQDNKTRRYTEEIKKLQ-TYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKGERKNNNIIIKVENLLNDIMTSPNVTNTEWVTTELGHVHAELDI-MFKEVKDKQYKEFV 1396
            K +K +  FSS++ +I   +E       RD +K+   G+ S GKS ++NAML +    SG  HTT+ FV V  S+ ++                    E + IS  ++   A   E        I V        LL   ++++D PG    + I   I     +AD+F+ V N    L   +R FF    +  +KP+VFI+ N+WD SDN+ ++S +  +E+  E  SKFL D L ++ + +I +R++F+S+ E   +R   + +  K S+  + R+DEF RFE   ++ I      KT+     ++ L   Y   E     E + KE+    IS   K I + K+    I+  GER        V+ L      S      E +   L H+ AE     F+     QYK  +
Sbjct:   94 KEQKEIGVFSSQVSSISKLFE-------RDHMKVVFVGQTSNGKSTVVNAMLYNRILPSGIGHTTNCFVSVSGSDANT-----------PYIIDSLSSEQQPISNVLQLANALHPEGSLNQSGLIRVFWPTTKCRLLGDDVDLIDSPGLDLSNDINQWIDDYCMDADVFVLVANAEATLKVAERAFFFKVNEKLSKPNVFILNNRWDASDNEIDDSPERVREQHLEYASKFLADELKVVSRSKILDRVFFVSARETLLYRTTENWTRFKESQAVRDRYDEFRRFEQAFERTI-CKSAMKTKFEHRIVRGLDIAYSLAEIAGKAETLSKEQ----ISGRIKEINERKENAARIRQLGERSLKCCSALVDRLAATSRASVARAMNEEIDHVLPHIVAEFSYSQFRPQHLLQYKRML 484

[Close]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A0R3T4T6 (Dynamin-type G domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS2073 PE=3 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 1.473e-23
Identity = 110/384 (28.65%), Postives = 175/384 (45.57%), Query Frame = 2

Query:  173 ITEEEWKVKKTVLNFSSKLDNIESKYE---VITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKS-EDDSYXXXXXXXXXXXXXXXXXXEEIERIS---GDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----------------KKRFDEFTRFEYNLKKYISAPQDNKTR----RYTEEIKKLQTYLCKECKDFKENIFKEK----RYSLISKYR--KLIEDLKDFKKEIK 1216
            ++EE  K     L  SS  D +E  +E    I + ++R+ +K   FG+ S GKS ++NAMLG     SG  HTTS FV V+ + ++  Y  +    D      T   + IE +S     +   K  ++  I +        LLK+ +  +D PG      +   I ++  +AD+FI V N    L   ++ FF       +KP++FI+ N+WD S  + E + Q+ KE+  + C  FL D L +  +EE  ER++F+S+ E+   R +  +                         + R  EF+ FE   +K +S   D+ TR     +TE+ K+L  Y  +  +   E   +EK    RY  IS  R  KL E L+    +IK
Sbjct:   58 LSEEAGKRLSPALEKSSSTD-LEPHFEKVRQIQQIISRNQMKCAFFGRTSNGKSTVINAMLGSRILPSGIGHTTSCFVQVQGTNQEQGYLQQESIPDSVNNGTTSEPQPIESVSQLAHSLSSVKLASDAIIYLFWPSSSCNLLKEDVAFLDSPGVNVDPDMDAWIDRHCLDADVFILVANAESTLMQAEKDFFYRVSGRISKPNIFILNNRWDASAGEAELADQV-KEQHMQRCVAFLTDELQVCGREEAMERVFFISAREVLTIRAKALNGGTPPGAAPNIGTPSSGGYPLADGWQARLLEFSTFEGVFEKILS---DSATRTKFASHTEQGKELAAYFRQLMEATYEAALEEKDAGIRYRRISHVRLEKLNEKLRQASVDIK 436

[Close]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A1W4V389 (transmembrane GTPase fzo isoform X2 OS=Drosophila ficusphila OX=30025 GN=LOC108091614 PE=3 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 2.524e-23
Identity = 94/340 (27.65%), Postives = 159/340 (46.76%), Query Frame = 2

Query:  236 IESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEIS-ERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFDEFTRFEYNLKKYISAPQ-----DNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKGE 1228
            +  K   I + + R  +K+  FG+ S GKS ++NAML +    S   HTTS F  V+ + DD       + +    D +   E     S      +      I  S C    +LL   + ++D PG    +Q+ DC+ +   +AD+FI VLN    ++  +R FFK      ++P++FI+ N+WD + N + E  Q  K++  E C K L +DL +   EE + +RIY +S+ E  Q R   +      +   ++R+ EF RFE +    ++        ++      E + +LQT L K        + KE     + + R L  +++D +KEI+ + E
Sbjct:   46 LADKISSIDKVLARKRMKVAFFGRTSNGKSAVINAMLHERILPSAMGHTTSCFCQVQANGDDEPEHVRIEEEEQQLDLSSLNELASAHSPRALKPRTLLYVNIPKSRC----SLLDYDVVLMDTPGVDVTAQLDDCLDRYCMDADVFILVLNAESTISRVERQFFKDVSSKLSRPNLFILNNRWDVASNQEPEMEQQVKDQHMERCLKLLIEDLRVYSDEEQAKKRIYHISALEALQLR---NGCKTNPNPQTQERYLEFQRFEADFANCLAESALKTKFEHHLISAQEVLTQLQTTLLKPLATKVNQLMKEN----VDRRRDLYVEMRDSRKEIQERTE 374

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239])

HSP 1 Score: 104.76 bits (260), Expect = 7.657e-23
Identity = 79/286 (27.62%), Postives = 144/286 (50.35%), Query Frame = 2

Query:  218 SSKLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKS-EDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            S++L  IES   K  VI E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ + ED +Y       +          + + +++  +  +++  A   ++V        LL+  + +VD PG+   +Q+   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K+   + C  FL ++L ++ +EE    I+F+S+ E+   R++    + ++        + R  EF  FE   ++ IS
Sbjct:   52 STQLQEIESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYLKTEGSEEEKSI------KTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQH-TDRCVNFLVEELKVVDREEAPNHIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQSFERTFEECIS 330

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239])

HSP 1 Score: 104.375 bits (259), Expect = 8.390e-23
Identity = 79/286 (27.62%), Postives = 144/286 (50.35%), Query Frame = 2

Query:  218 SSKLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKS-EDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            S++L  IES   K  VI E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ + ED +Y       +          + + +++  +  +++  A   ++V        LL+  + +VD PG+   +Q+   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K+   + C  FL ++L ++ +EE    I+F+S+ E+   R++    + ++        + R  EF  FE   ++ IS
Sbjct:   52 STQLQEIESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYLKTEGSEEEKSI------KTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQH-TDRCVNFLVEELKVVDREEAPNHIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQSFERTFEECIS 330

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44])

HSP 1 Score: 101.293 bits (251), Expect = 9.565e-22
Identity = 72/274 (26.28%), Postives = 140/274 (51.09%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFD----EFTRFEYNLKKYIS 1039
            SK   I E ++R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++ +             +++ K ++ + +++  +  ++   A   + V        LL+  + +VD PG    +++   I K   +AD+F+ V N    L   ++ FF    +  + P++FI+ N+WD S ++ E   ++ ++ ++  CS FL D L ++ + + S+RI+F+S+ E+ Q R++    + ++     + F     EF  FE   ++ IS
Sbjct:   83 SKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNE-----AFLLTEGSEERKNVKTVNQLAHALHQDEDLDAGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMEEVRRQHMD-RCSSFLVDELGVVDRAQASDRIFFVSAKEVLQARVQKAQGMPEAGGALAEGFQARMFEFQNFERRFEECIS 350

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000043809.1 (mitofusin-1-like [Source:NCBI gene;Acc:103034819])

HSP 1 Score: 99.3673 bits (246), Expect = 3.012e-21
Identity = 72/280 (25.71%), Postives = 139/280 (49.64%), Query Frame = 2

Query:  224 KLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQD-LDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            ++ +   K E I E + R  +K+  FG+ S GKS ++NAML +    SG  HTT+ F+ V+ ++ D             +++ K I+ + +++  +  ++   +   + V        LL+  + ++D PG+   S++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S+ + E    + K+ ++  C  FL D L ++  ++   RI+F+S+ E    RI     + ++        + R  EF  FE   +++IS
Sbjct:   57 EIQSCSRKLEAIWEVLARRQMKVAFFGRTSNGKSTVINAMLRERVLPSGIGHTTNCFISVEGTDGDQ-----AFLTTENSEERKSIKTVNQLAHALHMDRNLDSGCLVRVFWPKTKCALLRDDLVLMDSPGTDVTSELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVSERISKPNIFILNNRWDASETEPEYLDGVRKQHMD-RCVSFLVDELKVVSPDQAPNRIFFVSAKEALSARIHRAQGMPETGAALADGFQDRLQEFQSFERTFEEFIS 330

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
Match: EDO42379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1L1])

HSP 1 Score: 94.3597 bits (233), Expect = 4.113e-20
Identity = 90/342 (26.32%), Postives = 160/342 (46.78%), Query Frame = 2

Query:   56 SILPETLKQLKNIRKTVSEIENNDKINYGKISEINNK----CDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSED-DSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDND-DEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA-----KKRFDEFTRFEYNLKKYIS 1039
            S L   +K  K I +TVSEI        GK  +  N+    C+I E+    K  +  F+  +     +   ITE + RD +K+  FG+ S GKS ++NAML D     G  HTT+ F+ V  S+  D Y           +D+ + ++ + +I+  +   K   +  ++V        +L + + +VD PG      +   I K+  +AD+F+ V N    L   ++ FF       +KP++FI+ N+WD S  + D E  ++ K++  +    FL ++L  + K++  +R++F+S+ E    R++    + +            R  EF  FE+  ++ IS
Sbjct:   27 SPLHNFVKAKKKINETVSEI--------GKYLDEANRFICGCEIAED---YKSNIKGFACDVAGFLGQVASITEVIARDQMKVAFFGRTSNGKSTVVNAMLQDRILPMGIGHTTNCFLSVNGSDSADPY------ILIPESDERRNVKTLGQIAHALFEEKLDHSSLVQVYWPKSRCKMLSEDVVLVDSPGIDVSPDLDLWIDKHCLDADVFVLVCNAESTLMVTEKNFFHKVNQKLSKPNIFILNNRWDASAGEPDVEMMELVKKQHLQRNVDFLSKELKCVDKKQAEDRVFFVSAKETLMSRMQKHQGMPEEGGAIHVDGFHGRKLEFENFEHKFEECIS 351

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009])

HSP 1 Score: 107.457 bits (267), Expect = 1.044e-23
Identity = 77/282 (27.30%), Postives = 142/282 (50.35%), Query Frame = 2

Query:  221 SKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            S++     K  VI E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++DD SY       +          + + +++  +  +++  A   + V        LL+  + +VD PG+   +Q+   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S N+ E    + K+   + C  FL ++L ++ +E+   RI+F+S+ E+   R++    + ++        ++R  EF  FE   ++ IS
Sbjct:   67 SEIQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSDEEKSI------KTVNQMAHALHMDESLDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQH-TDRCVNFLVEELKVVDREQAPNRIFFISAKEVLNSRMQRAQGMPETGGALAEGFQERLKEFQSFERRFEECIS 341

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009])

HSP 1 Score: 107.071 bits (266), Expect = 1.200e-23
Identity = 77/282 (27.30%), Postives = 142/282 (50.35%), Query Frame = 2

Query:  221 SKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFEYNLKKYIS 1039
            S++     K  VI E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++DD SY       +          + + +++  +  +++  A   + V        LL+  + +VD PG+   +Q+   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S N+ E    + K+   + C  FL ++L ++ +E+   RI+F+S+ E+   R++    + ++        ++R  EF  FE   ++ IS
Sbjct:   67 SEIQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSDEEKSI------KTVNQMAHALHMDESLDAGCLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQH-TDRCVNFLVEELKVVDREQAPNRIFFISAKEVLNSRMQRAQGMPETGGALAEGFQERLKEFQSFERRFEECIS 341

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000009003.2 (pep primary_assembly:ASM223467v1:17:11595384:11602171:-1 gene:ENSORLG00000007178.2 transcript:ENSORLT00000009003.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 95.1301 bits (235), Expect = 6.335e-21
Identity = 74/289 (25.61%), Postives = 140/289 (48.44%), Query Frame = 2

Query:  218 SSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSE-DDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICM-------DDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTA----KKRFDEFTRFE--YNLKKY 1033
            S ++ +  +K   I + + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ ++ D++Y                  EE   IS   +   A   +    S C+           LL+  + ++D PG+    ++   I K   +AD+F+ V N    L + +++FF    +  +KP++FI+ N+WD S  + +   ++ K+ ++  C  FL ++L ++   E   RI+F+S+ E+   R++    + ++         +R  EF RFE  + ++K+
Sbjct:   53 SLEMQSCATKLYTIRDVLLRRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDGDEAYLTSEAS------------EERRSISTVNQLAHALHMDPTLDSSCLVKVFWPKSRCALLRNDLVLMDSPGTDVTLELDSWIDKFCLDADVFVLVGNAESTLMNTEKLFFHKVSERISKPNIFILHNRWDASVTEPDYIQEVRKQHLD-RCVGFLAEELGVVGPNEAPGRIFFISAKEVLSSRMQRAQGMPETGGALAEGFHERLTEFQRFERTFEVRKH 328

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn2 (mitofusin 2 [Source:NCBI gene;Acc:101170481])

HSP 1 Score: 98.2117 bits (243), Expect = 8.582e-21
Identity = 73/273 (26.74%), Postives = 131/273 (47.99%), Query Frame = 2

Query:  242 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFL-QDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFD----EFTRFEYNLKKYIS 1039
            SK   I E + R  +K+  FG+ S GKS ++NAML D    SG  HTT+ F+ V+ + D S      +            +    +  D       A   + V        LL+  + +VD PG    +++   I K   +AD+F+ V N    L   ++ FF    +  + P++FI+ N+WD S ++ E   ++ ++ ++  CS FL ++L ++ + + S+RI+F+S+ E+ Q R++    + ++     + F     EF  FE   ++ IS
Sbjct:   83 SKVAGIGEVLARRHMKVVFFGRTSNGKSTVINAMLCDKVLPSGIGHTTNCFLRVEGT-DGSEGFLLTEGSEEKKSIKTVNQLAHALHQD---QDLDAGSLVCVMWPKVKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMDEVRRQHMD-RCSNFLVEELGVVDRAQASDRIFFVSAKEVLQARMQRVQGMPEAGGALAEGFQARMFEFQNFERRFEECIS 350

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014762.1 (SMESG000014762.1)

HSP 1 Score: 1103.97 bits (2854), Expect = 0.000e+0
Identity = 594/628 (94.59%), Postives = 608/628 (96.82%), Query Frame = 2

Query:   47 MNISILPETLKQLKNIRKTVSEIENNDKINYGKISEINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFDEFTRFEYNLKKYISAPQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKGERKNNNIIIKVENLLNDIMTSPNVTNTEWVTTELGHVHAELDIMFKEVKDKQYKEFVSFLKNQEGIGKESNFSKEGKPAFKSMWRTSIVKPSDKGLDVETADAVNPAKTGDVLNKTVEILPLLGQLPTKIFALASSALIISGLAMTAASAVYASYANDMKVXXXXXXXXXXXXXLDSKKNIFNSNIKDNVEAITEHFIEKANEINGIFQRKIDMFNEYWSKIEEIFRESHEIIGN 1930
            MN  IL ET  + +NIRK V EI+  D+INYGKISE+N KCDITEEEWKV + +LNFSSKLDNI+SK+EVI EKVNRD+VKIFLFGKVSVGKS LLN MLGDNYFASGTAHTTSSFVHVKKSEDDSYRIKTKDTDRTFTDK +FI+EIE +SGDIKGNKATANE IEVSI MDDE+LLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFDEFTRFEYNLKKYISAPQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKGERKNNNIIIKVENLLNDIMTSPNVTNTEWVTTELGHVHAELDIMFKEVKDKQYKEFVSFLKNQEGIGKESNFSKEGKPAFKSMWRTSIVKPSDKGLDVETADAVNPAKTGDVLNKTVEILPLLGQLPTKIFALASSALIISGLAMTAASAVYASYANDMKVKEQEQQKQNIIQQLDSKKNIFNSNIKDNVEAITEHFIEKANEINGIFQRKIDMFNEYWSKIEEIFRESHEIIGN
Sbjct:    1 MNTEILTETENRFENIRKIVKEIKRYDEINYGKISEMNKKCDITEEEWKVDQILLNFSSKLDNIKSKFEVINEKVNRDIVKIFLFGKVSVGKSTLLNTMLGDNYFASGTAHTTSSFVHVKKSEDDSYRIKTKDTDRTFTDKKEFIKEIEIMSGDIKGNKATANENIEVSIRMDDESLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFDEFTRFEYNLKKYISAPQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKGERKNNNIIIKVENLLNDIMTSPNVTNTEWVTTELGHVHAELDIMFKEVKDKQYKEFVSFLKNQEGIGKESNFSKEGKPAFKSMWRTSIVKPSDKGLDVETADAVNPAKTGDVLNKTVEILPLLGQLPTKIFALASSALIISGLAMTAASAVYASYANDMKVKEQEQQKQNIIQQLDSKKNIFNSNIKDNVEAITEHFIEKANEINGIFQRKIDMFNEYWSKIEEIFRESHEIIGN 628

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014753.1 (SMESG000014753.1)

HSP 1 Score: 723.005 bits (1865), Expect = 0.000e+0
Identity = 401/626 (64.06%), Postives = 484/626 (77.32%), Query Frame = 2

Query:   47 MNISILPETLKQLKNIRKTVSEIENNDKINYGKISEINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFDEFTRFEYNLKKYISAPQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKGERKNNNIIIKVENLLNDIMTSPNVTNTEWVTTELGHVHAELDIMFKEVKDKQYKEFVSFLKNQEGIGKESNFSKEGKPAFKSMWRTSIVKPSDKGLDVETADAVNPAKTGDVLNKTVEILPL--LGQLPTKIFALASSA---LIISGLAMTAASAVYASYANDMKVXXXXXXXXXXXXXLDSKKNIFNSNIKDNVEAITEHFIEKANEINGIFQRKIDMFNEYWSKIEEIFRE 1909
            MNISILPETLKQLKNIRKTVSEIENNDKINYGKISEINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYRIKTKDTDRTFTDKTKFIEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSK KI EECSKFL+ L++ K++EI +RIYF S+ EM Q RIEN+DSL+ S    KKRF++F RFEYNLKKYI+ PQDNKTRRY +EIK +Q +L  E   F+ +IF EK  SLI KY K ++D++DFK  I  K +   N+++ ++E++ N+I+ SP++ ++EWVT++L H  +E+ +  +E + KQYK+F+ F+K+++ I  ++  S+  +   K MW   IV P+D           N +K   ++ + +E L +  +  +P ++FA   S    L+I  +  + +     S                   QL+S+++  +  I++NV  I E+++EKANEI  +FQ K  +FNEYW ++E I ++
Sbjct:    1 MNISILPETLKQLKNIRKTVSEIENNDKINYGKISEINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYRIKTKDTDRTFTDKTKFIEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFFSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFEYNLKKYINDPQDNKTRRYMQEIKNIQDFLNTEFMKFQADIFNEKNNSLIPKYEKWMKDMEDFKATILSKNDDVQNSLLKRLEDIHNEIIHSPDLRSSEWVTSQLEHFTSEMKLKLQEAQLKQYKDFIHFIKSKDLINGKTYLSETKELNIKLMWNPIIVNPTD-----------NVSKEACIVKEVMEKLAMIPIPNIPFQMFAQGVSLVGKLVIKRIEDSESEQHRQSIIQ----------------QLNSQRSNMSRIIEENVNEIKEYYMEKANEIIQLFQEKSKLFNEYWRRLEGILKD 599

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014759.1 (SMESG000014759.1)

HSP 1 Score: 211.075 bits (536), Expect = 8.965e-60
Identity = 148/442 (33.48%), Postives = 244/442 (55.20%), Query Frame = 2

Query:  185 EWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGN---KATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLI--KSSKTAKKRFDEFTRFEYNLKKYISAPQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISK--YRKLIEDLKDFKKEIKLKGERKNNNIIIKVENLLNDIMTSPNVTNTEWVTTELGHVHAEL--DIM-----FKEVKDKQYKEFVSFLKNQEGIGKESNFSKEGKPAFK 1468
            E K+   + +F  K + IE+K   I  KV +D +KI  FGKVS GKS++LN +LG N F S  A TTS FV V KS+   + ++   ++  F       ++++ ++  +  N   +    +T++V + + +E +LK   EIVDCPGS NK ++T+CIKK S ++DIFIFV+   LTD+++ FF+YQ   S+KPD+F+++N+WD SD D +E+T  S++KI +E    L        +E SERI+F+S+ EMF+ R+EN D  +  K+ +    R  EFT FE +L  YI  P+  KT+R+  E+      +    KDFKE +    +    +K   + L++ LK  K ++     +  + I  +++  + D+  + N  N   + T+L  +  ++  D++       E+ +K  K+F      +  +GK    +KE KP  K
Sbjct:   41 ESKILHLIEDFIKKFEIIETKIGFIEGKVKKDSIKISFFGKVSAGKSRVLNTILGGNIFVSAVADTTSCFVSVTKSDRRCHYLRVDGSEDNFGSLENLKDKVKELTTYLSKNINRRLDTAKTVQVFLNIKNE-ILKNKTEIVDCPGSNNKGEVTECIKKQSLDSDIFIFVMTCTLTDEEKDFFEYQSKLSSKPDIFVLVNKWDNSDKDRQENTNKSRDKIKKEIINLLTKNGNFSSKEASERIFFVSALEMFKSRVENADVFVNKKNQEAIAMRNYEFTSFEKSLSNYIDNPEKKKTKRHFREVTAAIKEIENVRKDFKEELLGTNKLEEFNKNPMKHLLDSLKRIKSDLISHINKNCSYISDQIQYEVEDLKRNINRNNVRDINTKLNSLPTKVSTDLLNLQSDSNEIIEKMKKKF------KRVMGKHKFKNKEEKPTLK 475

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014755.1 (SMESG000014755.1)

HSP 1 Score: 202.601 bits (514), Expect = 1.198e-57
Identity = 138/435 (31.72%), Postives = 231/435 (53.10%), Query Frame = 2

Query:  203 TVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGN---KATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIENDDSL--IKSSKTAKKRFDEFTRFEYNLKKYISAPQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKGE-------RKNNNIIIKVENLLNDIMTSPNVTNTEWVTTELGHVHAELDIMFKEVKDKQYKEFVSFLKN-QEGIGKESNFSKEGKPAFK 1468
            T+ NF  K + IE+K   I  KV +D +KI  FG VS GKSK+LN ++G+N F S  A TTS FV V+KS+   + ++ + ++  F   T    +++ ++  +  N   +    +T++V + +++E ++K   EI DCPGS NK ++T+CI + S ++DIFIFV+   LT++++ FF+YQ   S+KPD+F+++N+WD+SD D    T+ S+ KI  E    L        EE S+RI+F+S+ EMF+ RIE  +     ++ +  + R++EF  FE +L +YI  P+ NK  R+  E+++    L    + FK  +FK K    +  Y     D+KD    +    E       R+   I + +    +D+ T     N +   + L  V   +      ++    K+  +  K+ +  +GK     KE KP  K
Sbjct:   47 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENE-IMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTCTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKEIFGNQRTRRAIEMRYEEFLSFEESLSRYIDNPEINKLERHDREVRETTRNLESIIESFKTELFKHKDLRELKTY-----DMKDLSGRLDKAYECILKDLLRETKEIHMNLSTNCHDLRTFLTRNNIQGTCSMLNTVTTRVSNDLMNIQSNLNKKLQTMKKDFKRVMGKHKFIKKEEKPTLK 475

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000070111.1 (SMESG000070111.1)

HSP 1 Score: 191.43 bits (485), Expect = 1.937e-53
Identity = 122/351 (34.76%), Postives = 213/351 (60.68%), Query Frame = 2

Query:   41 KKMNISILPETLKQLKNIRKTVSEIENNDKINYGKISEINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGDIKGNKATANETIEVSICM-DDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFDEFTRFEYNLKKYISAPQDNKTRRYTEEIKKL 1090
            KKM+ +I  +  ++++  +K ++E+EN     Y    E+   C    +EWKV+K +  F  +   +E++   I E++++  +KIF FG VS GK++L+NA+LG  +F S   HTT  FVH+ KS D  Y+I  K+ +  +  K K IEE+E+IS   K   + + E+++V I + DD  +LK  +E++D PG+G+  ++ +C++ +  +ADI I++L   ++++D  FF  + + +TKPD+FI++N+WD+SD D +     + + +  +C   +      K ++I +RI F+S+ E+F +RI+N +    S++  K R+ +F RFE  +++YI  PQ  KTRRY  EIK L
Sbjct:   13 KKMSQNIDSDARQEMRKAKKLLTELEN-----YIGFEEL---C----KEWKVQKKIKKFKDRFVELENQLNDIQEEISKKNIKIFFFGSVSSGKTRLINAILGGEFFMSTMNHTTKCFVHIMKSPDAKYKIVHKNQEFIYESKNKIIEEVEKISTFNKETSSMSQESVKVFIPIGDDNKILKGNVELIDSPGTGDIEELIECVQNHLSDADICIYLLCNDVSEEDERFFNIRINRTTKPDIFILVNKWDQSDQDQDSRLCETYKNLVGKCFGLVGKFGGPKTKDIDKRIIFISAIEVFGYRIKNKEP---SNRNQKIRYADFERFEDQIEEYIQNPQQLKTRRYKREIKTL 348

The following BLAST results are available for this feature:

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Sea Lamprey
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Yeast
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MFN1	9.214e-22	26.74	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN2	1.779e-21	25.91	mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]	[more]
MFN2	1.779e-21	25.91	mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]	[more]
MFN1	5.889e-21	26.74	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN1	5.889e-21	26.74	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
fzo-1	9.419e-19	24.76	Transmembrane GTPase fzo-1 [Source:UniProtKB/Swis...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Marf	6.908e-25	27.08	gene:FBgn0029870 transcript:FBtr0070910	[more]
Marf	6.908e-25	27.08	gene:FBgn0029870 transcript:FBtr0070909	[more]
Marf	1.077e-24	27.14	gene:FBgn0029870 transcript:FBtr0343373	[more]
fzo	1.462e-24	26.74	gene:FBgn0011596 transcript:FBtr0084399	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mfn1b	1.128e-21	26.91	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn1b	1.561e-21	26.86	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn1b	1.561e-21	26.86	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn2	2.197e-21	26.64	mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]	[more]
mfn1b	4.963e-21	27.31	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mfn1	1.207e-21	27.37	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	1.289e-21	27.37	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	1.472e-21	27.37	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	1.563e-21	27.37	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	1.603e-21	27.37	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mfn1	6.461e-22	27.11	mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664]	[more]
Mfn1	6.461e-22	27.11	mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664]	[more]
Mfn2	4.846e-21	26.01	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]
Mfn2	4.846e-21	26.01	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]
Mfn2	4.846e-21	26.01	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q7YU24\|MARF_DROME	6.924e-24	27.08	Transmembrane GTPase Marf OS=Drosophila melanogast...	[more]
sp\|O18412\|FZO_DROME	1.466e-23	26.74	Transmembrane GTPase fzo OS=Drosophila melanogaste...	[more]
sp\|Q8R4Z9\|MFN1_RAT	2.722e-21	27.11	Mitofusin-1 OS=Rattus norvegicus OX=10116 GN=Mfn1 ...	[more]
sp\|Q8R500\|MFN2_RAT	2.745e-21	26.37	Mitofusin-2 OS=Rattus norvegicus OX=10116 GN=Mfn2 ...	[more]
sp\|Q811U4\|MFN1_MOUSE	4.519e-21	27.11	Mitofusin-1 OS=Mus musculus OX=10090 GN=Mfn1 PE=1 ...	[more]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5E4MV73	9.169e-25	28.29	Dynamin superfamily,Fzo/mitofusin HR2 domain,P-loo...	[more]
A0A1A9X2I7	4.511e-24	29.45	Dynamin-type G domain-containing protein OS=Glossi...	[more]
A0A0D2X0Q9	5.727e-24	28.02	Transmembrane GTPase Marf OS=Capsaspora owczarzaki...	[more]
A0A0R3T4T6	1.473e-23	28.65	Dynamin-type G domain-containing protein OS=Rodent...	[more]
A0A1W4V389	2.524e-23	27.65	transmembrane GTPase fzo isoform X2 OS=Drosophila ...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
mfn1b	7.657e-23	27.62	mitofusin-1 [Source:NCBI gene;Acc:103030239]	[more]
mfn1b	8.390e-23	27.62	mitofusin-1 [Source:NCBI gene;Acc:103030239]	[more]
mfn2	9.565e-22	26.28	mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]	[more]
ENSAMXT00000043809.1	3.012e-21	25.71	mitofusin-1-like [Source:NCBI gene;Acc:103034819]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO42379	4.113e-20	26.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
mfn1b	1.044e-23	27.30	mitofusin 1 [Source:NCBI gene;Acc:101158009]	[more]
mfn1b	1.200e-23	27.30	mitofusin 1 [Source:NCBI gene;Acc:101158009]	[more]
ENSORLT00000009003.2	6.335e-21	25.61	pep primary_assembly:ASM223467v1:17:11595384:11602...	[more]
mfn2	8.582e-21	26.74	mitofusin 2 [Source:NCBI gene;Acc:101170481]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000014762.1	0.000e+0	94.59	SMESG000014762.1	[more]
SMESG000014753.1	0.000e+0	64.06	SMESG000014753.1	[more]
SMESG000014759.1	8.965e-60	33.48	SMESG000014759.1	[more]
SMESG000014755.1	1.198e-57	31.72	SMESG000014755.1	[more]
SMESG000070111.1	1.937e-53	34.76	SMESG000070111.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30022278 ID=SMED30022278|Name=Dynamin-type G domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2015bp
AATTTATTGTTAGAATTTTTATATCCGCATTTCAGATTTGAAAAAAATGA
ATATTTCAATTTTACCCGAAACATTAAAGCAATTGAAGAATATAAGAAAA
ACTGTCAGCGAAATAGAAAATAACGATAAAATTAATTATGGAAAAATATC
CGAAATAAATAACAAATGTGATATAACAGAAGAAGAGTGGAAAGTAAAAA
AGACCGTATTAAATTTCTCAAGCAAATTAGACAACATCGAAAGTAAATAC
GAAGTCATCACCGAAAAAGTCAACAGAGATGTTGTCAAAATATTTCTTTT
TGGAAAAGTTTCAGTTGGCAAAAGCAAACTCCTGAATGCGATGTTGGGCG
ACAATTACTTTGCCTCGGGCACAGCTCACACAACGAGCAGTTTTGTCCAT
GTCAAGAAATCGGAGGACGACAGCTACAGGATCAAAACTAAGGATACTGA
TCGAACGTTCACTGACAAAACAAAGTTCATTGAAGAAATTGAACGCATTT
CTGGGGACATAAAAGGTAATAAAGCCACGGCTAATGAAACCATTGAAGTG
TCGATATGCATGGATGACGAGACTCTATTGAAAAAAGGCATAGAAATTGT
CGACTGCCCCGGATCCGGAAACAAATCTCAAATTACAGACTGCATTAAGA
AAAATTCTCAAGAAGCGGATATATTCATATTTGTGTTGAATTACGCATTG
ACGGACGATGATAGGGTATTCTTCAAATATCAAGAGGATTCTTCAACTAA
ACCGGACGTTTTCATTGTTATAAATCAGTGGGACGAGTCTGATAATGATG
ATGAGGAGTCAACTCAAATGAGCAAAGAGAAAATCAATGAAGAATGTTCT
AAATTCCTGCAAGATCTGGATTTAATGAAAAAAGAAGAAATCTCTGAAAG
AATTTATTTCCTTTCATCTTCTGAAATGTTTCAATTTCGTATAGAAAATG
ATGACAGTTTAATCAAGTCTAGTAAGACTGCTAAGAAGCGATTTGACGAA
TTTACTCGATTTGAATACAATCTGAAGAAATACATCAGCGCGCCTCAAGA
CAACAAGACCCGTCGATACACTGAAGAAATAAAAAAACTGCAAACTTATT
TATGCAAAGAATGCAAAGATTTCAAAGAAAACATTTTCAAAGAAAAGAGA
TATTCCTTAATAAGCAAATATAGAAAATTAATTGAAGATTTAAAAGACTT
CAAAAAAGAGATAAAACTGAAAGGTGAAAGGAAAAATAACAACATAATTA
TAAAAGTAGAAAATCTGTTAAATGACATTATGACCAGCCCGAATGTGACA
AACACAGAATGGGTCACGACGGAACTGGGACATGTCCATGCGGAACTGGA
TATCATGTTCAAGGAAGTAAAGGATAAACAATACAAGGAATTTGTCAGTT
TCCTAAAAAATCAAGAGGGAATTGGTAAGGAGAGTAATTTTTCAAAGGAG
GGTAAGCCGGCTTTCAAGAGCATGTGGAGAACGTCAATCGTGAAACCTAG
TGACAAGGGACTCGATGTAGAGACTGCAGATGCGGTGAATCCAGCAAAGA
CCGGTGACGTGTTAAATAAGACCGTAGAAATATTGCCATTGCTTGGACAA
CTTCCAACAAAGATATTTGCGTTAGCGTCTTCCGCTTTAATTATTTCTGG
CCTTGCTATGACGGCTGCCTCGGCCGTTTATGCCTCCTACGCAAATGATA
TGAAGGTAAAGGAGCAGGAACAGCAAAAGCAAAATATTATCCAGCAGTTA
GATTCCAAAAAAAATATATTTAATAGCAATATCAAGGATAATGTGGAAGC
TATTACCGAACATTTCATAGAGAAAGCAAATGAAATTAATGGAATTTTCC
AAAGAAAAATAGATATGTTCAATGAATATTGGAGTAAGATAGAAGAGATA
TTTAGAGAAAGTCATGAAATAATTGGAAATTGAATATTTTTGAAACTTGA
AATCTTCAATCTTTTAGTTATGCTATACTTTTAACTATTTGCATCATATG
TGATACATAGGATAG

protein sequence of SMED30022278-orf-1

>SMED30022278-orf-1 ID=SMED30022278-orf-1|Name=SMED30022278-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=629bp
MNISILPETLKQLKNIRKTVSEIENNDKINYGKISEINNKCDITEEEWKV
KKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAML
GDNYFASGTAHTTSSFVHVKKSEDDSYRIKTKDTDRTFTDKTKFIEEIER
ISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCI
KKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDN
DDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIE
NDDSLIKSSKTAKKRFDEFTRFEYNLKKYISAPQDNKTRRYTEEIKKLQT
YLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKGERKNNNI
IIKVENLLNDIMTSPNVTNTEWVTTELGHVHAELDIMFKEVKDKQYKEFV
SFLKNQEGIGKESNFSKEGKPAFKSMWRTSIVKPSDKGLDVETADAVNPA
KTGDVLNKTVEILPLLGQLPTKIFALASSALIISGLAMTAASAVYASYAN
DMKVKEQEQQKQNIIQQLDSKKNIFNSNIKDNVEAITEHFIEKANEINGI
FQRKIDMFNEYWSKIEEIFRESHEIIGN*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0000140	anterior region of the whole animal
PLANA:0002028	dorsal-ventral muscle cell
PLANA:0002032	epidermal cell
PLANA:0002075	pigment cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR027094	Mitofusin_fam
IPR027417	P-loop_NTPase
IPR022812	Dynamin_SF

Vocabulary: **molecular function**
Term	Definition
GO:0003924	GTPase activity
GO:0005525	GTP binding

Vocabulary: **cellular component**
Term	Definition
GO:0005741	mitochondrial outer membrane
GO:0016021	integral component of membrane

Vocabulary: **biological process**
Term	Definition
GO:0008053	mitochondrial fusion

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 456..476
None	No IPR available	COILS	Coil	Coil	coord: 162..182
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 32..316 e-value: 5.5E-11 score: 44.1
None	No IPR available	TMHMM	TMhelix		coord: 425..447
IPR022812	Dynamin superfamily	PFAM	PF00350	Dynamin_N	coord: 2..145 e-value: 9.6E-11 score: 42.0
IPR027094	Mitofusin family	PANTHER	PTHR10465	TRANSMEMBRANE GTPASE FZO1	coord: 1..370
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 2..153

Main menu

Dynamin-type G domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Owlery

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