Eukaryotic elongation factor 2 kinase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30022256 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Human
Match: EEF2K (eukaryotic elongation factor 2 kinase [Source:HGNC Symbol;Acc:HGNC:24615]) HSP 1 Score: 460.685 bits (1184), Expect = 4.228e-151 Identity = 275/654 (42.05%), Postives = 388/654 (59.33%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSE-------LKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQV-SSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKK----KARFKFDSSNSNDLKKGEDSLDA----------YMNRNHIHRP-SCAVSTDSCSL-------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ ++ + DP+ F L ++ TE+ R+ Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H WK A N+V+KRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DRP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFF+SH CN +CE++GLA FDL+P E K LQS++ +I T S +R+L S+P L+ L E+ +++ + + + + QK L + V S D+ D D N E ++ + + + R S ++ + EDSL + +N + +H P + AV+ + L ++G+SILG++H + HE GRF ++ E + E+ ++H + AA+L +EAI+ + + L P +L +++ E K KG+ YL KAA AG R S++ +A A D Q+ DW +HW +E D DE GE+D D P Y++ AR A M TGGYGL+KD +RS +LY++A + A AMKGRLA++YY+ +EE + +ME
Sbjct: 85 WKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAK--TILRGTEEKCGSPQVRTLSGSRP------PLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDNMASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKYESDEDSLGSSGRVCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFCEKG---EEWDQESAVFHLEHAANLGELEAIVGLGLMYSQL-PHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTD-CDEGGEYDGMQDEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQME 724
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Human
Match: EEF2K (eukaryotic elongation factor 2 kinase [Source:HGNC Symbol;Acc:HGNC:24615]) HSP 1 Score: 459.914 bits (1182), Expect = 7.461e-151 Identity = 275/654 (42.05%), Postives = 388/654 (59.33%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSE-------LKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQV-SSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKK----KARFKFDSSNSNDLKKGEDSLDA----------YMNRNHIHRP-SCAVSTDSCSL-------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ ++ + DP+ F L ++ TE+ R+ Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H WK A N+V+KRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DRP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFF+SH CN +CE++GLA FDL+P E K LQS++ +I T S +R+L S+P L+ L E+ +++ + + + + QK L + V S D+ D D N E ++ + + + R S ++ + EDSL + +N + +H P + AV+ + L ++G+SILG++H + HE GRF ++ E + E+ ++H + AA+L +EAI+ + + L P +L +++ E K KG+ YL KAA AG R S++ +A A D Q+ DW +HW +E D DE GE+D D P Y++ AR A M TGGYGL+KD +RS +LY++A + A AMKGRLA++YY+ +EE + +ME
Sbjct: 85 WKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAK--TILRGTEEKCGSPRVRTLSGSRP------PLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDNMASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKYESDEDSLGSSGRVCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFCEKG---EEWDQESAVFHLEHAANLGELEAIVGLGLMYSQL-PHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTD-CDEGGEYDGMQDEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQME 724
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Human
Match: EEF2K (eukaryotic elongation factor 2 kinase [Source:HGNC Symbol;Acc:HGNC:24615]) HSP 1 Score: 459.914 bits (1182), Expect = 7.461e-151 Identity = 275/654 (42.05%), Postives = 388/654 (59.33%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSE-------LKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQV-SSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKK----KARFKFDSSNSNDLKKGEDSLDA----------YMNRNHIHRP-SCAVSTDSCSL-------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ ++ + DP+ F L ++ TE+ R+ Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H WK A N+V+KRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DRP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFF+SH CN +CE++GLA FDL+P E K LQS++ +I T S +R+L S+P L+ L E+ +++ + + + + QK L + V S D+ D D N E ++ + + + R S ++ + EDSL + +N + +H P + AV+ + L ++G+SILG++H + HE GRF ++ E + E+ ++H + AA+L +EAI+ + + L P +L +++ E K KG+ YL KAA AG R S++ +A A D Q+ DW +HW +E D DE GE+D D P Y++ AR A M TGGYGL+KD +RS +LY++A + A AMKGRLA++YY+ +EE + +ME
Sbjct: 85 WKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAK--TILRGTEEKCGSPRVRTLSGSRP------PLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDNMASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKYESDEDSLGSSGRVCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFCEKG---EEWDQESAVFHLEHAANLGELEAIVGLGLMYSQL-PHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTD-CDEGGEYDGMQDEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQME 724
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Human
Match: EEF2K (eukaryotic elongation factor 2 kinase [Source:HGNC Symbol;Acc:HGNC:24615]) HSP 1 Score: 338.576 bits (867), Expect = 2.652e-108 Identity = 165/289 (57.09%), Postives = 208/289 (71.97%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSE-------LKQLQSSRGSSITSETIAVHQSTPLRSLRSSKP 1133
W+ ++ + DP+ F L ++ TE+ R+ Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H WK A N+V+KRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DRP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFF+SH CN +CE++GLA FDL+P E K LQS++ +I T S +R+L S+P
Sbjct: 85 WKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRH-KPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAK--TILRGTEEKCGSPQVRTLSGSRP 370
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Human
Match: ALPK1 (alpha kinase 1 [Source:HGNC Symbol;Acc:HGNC:20917]) HSP 1 Score: 77.0258 bits (188), Expect = 1.047e-13 Identity = 56/176 (31.82%), Postives = 91/176 (51.70%), Query Frame = 3
Query: 531 GNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNR---QPGVKKEVDIVRMSIIE-FSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQ--AFSHFTFERSGHELIVVDIQGV------GDLY-TDPQIHTSCRNGYGNGNLGPRGMALFFHS-HI-CNNVCEALGLAR 1013
G +V K Y E +F DV QM A+ + EFN+ + + ++ + +I+ D+ K +E +I G ++K ++N+ V + T A+ HF++E S H +VVD+QG G +Y TDPQIH+ + + N G RG+ FF++ H+ CN +C L L R
Sbjct: 1062 GRYVGKDYKEQKGLWHHFTDVERQMTAQHYVTEFNKRLYEQNIPTQIFYIPSTILLILEDKTIKGCISVEPYILGEFVKLSNNTKVVKTEYKATEYGLAYGHFSYEFSNHRDVVVDLQGWVTGNGKGLIYLTDPQIHSVDQKVF-TTNFGKRGIFYFFNNQHVECNEICHRLSLTR 1236
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Celegans
Match: efk-1 (Eukaryotic elongation factor 2 kinase [Source:UniProtKB/Swiss-Prot;Acc:O01991]) HSP 1 Score: 370.163 bits (949), Expect = 2.054e-116 Identity = 261/717 (36.40%), Postives = 368/717 (51.32%), Query Frame = 3
Query: 261 DSIKHLKVPKLWQSLARRTLM-LSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSEL-----------KQLQS---------SRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNED--SNEQIDNVIECLTQCAGDK--------------NEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSN-------------DLKKGE-------DSLDAYMNRNHIHRPSCAVSTDSCSLRMGE---SILGEIHHEISNMHEIGRFAD------------RNQLDEPINW--EAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFK------------GWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTV-----ETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSE 2138
D + K+ + W+ ARR DP+ F + E P ++ RY Y +I K W D V++ + F RGAMREC+RLKK S HG + N+V+KRY+ V+R V F+DV LQMDAKLWAEE+NR KK +DIV+M +IE D PLYHLEHFIEG YIKYNSNSGFV + R TPQAFSHFTFERSGH+++VVDIQGVGDLYTDPQIHT YG+GNLG RGMALFFHSH CN++CE + L+ F+L+P E+ KQ +S +R + I+SE + V + LR K +L + D+ + NED E I V + C+ D+ N QK++ + +S+ SG D SAS+ C R + DS S+ D +K E S+ A + + + + + D ++ S+LG+IH ++S HE+GRF + N PI + ++ ++H D+A +EA+L A+ LGL P +LLK T+ F G + AA G + +++ +A A + Q D+ + W +R V E +D F S + + A+MA M++ GGYGL++D ER+ L++EA + A AM G+LA+KYYE +E
Sbjct: 59 DPLHVRKLMETWRKAARRARTNYIDPWDEFNIHEYPVQRAKRYRYSAIRKQWTEDIVDVRLHPDSFARGAMRECYRLKKCSK-HGTSQDWSSNYVAKRYICQVDRRVLFDDVRLQMDAKLWAEEYNRYNPPKK-IDIVQMCVIEMIDVKGSPLYHLEHFIEGKYIKYNSNSGFVSNAARLTPQAFSHFTFERSGHQMMVVDIQGVGDLYTDPQIHTVVGTDYGDGNLGTRGMALFFHSHRCNDICETMDLSNFELSPPEIEATEVAMEVAAKQKKSCIVPPTVFEARRNRISSECVHVEHGISMDQLRKRK---TLNQSSTDLSAKSHNEDCVCPECIPVVEQLCEPCSEDEEDEEEDYPRSEKSGNSQKSRRSRMSISTRSSG-------------DESASRPRKCGFVDLNSLRQRHDSFRSSVGTYSMNSSRQTRDTEKDEFWKVLRKQSVPANILSLQLQQMAANLENDEDVPQVTGHQFSVLGQIHIDLSRYHELGRFVEVDSEHKEMLEGSENDARVPIKYDKQSAIFHLDIARKCGILEAVLTSAHIVLGL-PHELLKEVTVDDLFPNGFGEQENGIRDLEEFGSDLMEIAAEMGDKGAMLYMAHAYETGQHLGPNRRTDYKKSIDWYQRVVGFQEEEELDSDCGKTTFSSFAPLTRHEILAKMAEMYKEGGYGLNQDFERAYGLFNEAAEAAMEAMNGKLANKYYEKAE 756
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Celegans
Match: efk-1 (Eukaryotic elongation factor 2 kinase [Source:UniProtKB/Swiss-Prot;Acc:O01991]) HSP 1 Score: 368.237 bits (944), Expect = 1.315e-115 Identity = 262/726 (36.09%), Postives = 372/726 (51.24%), Query Frame = 3
Query: 261 DSIKHLKVPKLWQSLARRTLM-LSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSEL-----------KQLQS---------SRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNED--SNEQIDNVIECLTQCAGDK--------------NEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSN-------------DLKKGE-------DSLDAYMNRNHIHRPSCAVSTDSCSLRMGE---SILGEIHHEISNMHEIGRFAD------------RNQLDEPINW--EAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTI---------------------QPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTV-----ETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSE 2138
D + K+ + W+ ARR DP+ F + E P ++ RY Y +I K W D V++ + F RGAMREC+RLKK S HG + N+V+KRY+ V+R V F+DV LQMDAKLWAEE+NR KK +DIV+M +IE D PLYHLEHFIEG YIKYNSNSGFV + R TPQAFSHFTFERSGH+++VVDIQGVGDLYTDPQIHT YG+GNLG RGMALFFHSH CN++CE + L+ F+L+P E+ KQ +S +R + I+SE + V + LR K +L + D+ + NED E I V + C+ D+ N QK++ + +S+ SG D SAS+ C R + DS S+ D +K E S+ A + + + + + D ++ S+LG+IH ++S HE+GRF + N PI + ++ ++H D+A +EA+L A+ LGL P +LLK T+ +P ++F G + AA G + +++ +A A + Q D+ + W +R V E +D F S + + A+MA M++ GGYGL++D ER+ L++EA + A AM G+LA+KYYE +E
Sbjct: 59 DPLHVRKLMETWRKAARRARTNYIDPWDEFNIHEYPVQRAKRYRYSAIRKQWTEDIVDVRLHPDSFARGAMRECYRLKKCSK-HGTSQDWSSNYVAKRYICQVDRRVLFDDVRLQMDAKLWAEEYNRYNPPKK-IDIVQMCVIEMIDVKGSPLYHLEHFIEGKYIKYNSNSGFVSNAARLTPQAFSHFTFERSGHQMMVVDIQGVGDLYTDPQIHTVVGTDYGDGNLGTRGMALFFHSHRCNDICETMDLSNFELSPPEIEATEVAMEVAAKQKKSCIVPPTVFEARRNRISSECVHVEHGISMDQLRKRK---TLNQSSTDLSAKSHNEDCVCPECIPVVEQLCEPCSEDEEDEEEDYPRSEKSGNSQKSRRSRMSISTRSSG-------------DESASRPRKCGFVDLNSLRQRHDSFRSSVGTYSMNSSRQTRDTEKDEFWKVLRKQSVPANILSLQLQQMAANLENDEDVPQVTGHQFSVLGQIHIDLSRYHELGRFVEVDSEHKEMLEGSENDARVPIKYDKQSAIFHLDIARKCGILEAVLTSAHIVLGL-PHELLKEVTVDDLFPNGFGEQENGIRADKGQKPCDLEEF-GSDLMEIAAEMGDKGAMLYMAHAYETGQHLGPNRRTDYKKSIDWYQRVVGFQEEEELDSDCGKTTFSSFAPLTRHEILAKMAEMYKEGGYGLNQDFERAYGLFNEAAEAAMEAMNGKLANKYYEKAE 764
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Zebrafish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:ZFIN;Acc:ZDB-GENE-020916-2]) HSP 1 Score: 469.544 bits (1207), Expect = 1.603e-154 Identity = 270/651 (41.47%), Postives = 382/651 (58.68%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAG-----------------DKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFK--FDSSNSNDLKK-GEDSLDAY-MNRNHIHRPSC-AVSTDSCSL-----RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ + + DP+ F L E+ TE+ RY Y +IT W D+ +K+ + F +GAMRECFR KK+S F H ++WK A N+V+KRYME V+R VYFEDV LQM+AKLW EEFNR K+VDI++M ++E + RP PL+HLEH+IEG Y KYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHTS +G+GNLG RGMALFFHSH+CN +C ++GL RFDL+P+E+ QL + +++T+ S R S L+ L E + D + D+ I C G + + +N Q + DSGY ++ S+ EH+ + + + + S+ + +++ E+ Y +R+HIHRPSC AV + + ++G+SILG++H + HE GRF ++ DEP + + +YH + AA +EAI+ + +L L P +L ++P E KG+ +L +AA AG RPS++ +A A D DW+ +HW + ++ D DE GEFD D P Y++ AR+A M++ GG LD D +R+ +L++EA D A AMKGRLA++YY +EE + ME
Sbjct: 111 WKHAIEKAKAMPDPWAEFHLEEMETERCTRYRYSAITGEWAKDEIFIKVSSQTFGKGAMRECFRAKKLSNFSHSHNWKSASNYVAKRYMETVDRSVYFEDVRLQMEAKLWGEEFNRHR-PPKQVDIMQMCVVEMTTRPGSPLFHLEHYIEGKYTKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTSKGTDFGDGNLGVRGMALFFHSHLCNKICRSMGLTRFDLSPAEIAQLDCTNKLLQSAKTVLRGFEEQCGSPRVRTTSLGHMPVLLSRLSETSSVDESSDTDS-IPCSPLSMGVSVGRSPMGWSFMNEMNETHRSQNTEQQDSENGGDSGYPSEK-----------RSEGDPVEHHGQGRPIYNRHYSESDEDSVRRLTEEKWSFYHSSRSHIHRPSCVAVEVERLNALLLEKKIGKSILGKVHLAMVRYHEAGRFCEK---DEPWDQISAMYHLETAAMCGELEAIVALGQCYLQL-PHHILPEIELEPSEENSQKGFRFLLQAAEAGDRPSMILVARAFDTGLKLPSDRAMDWTEAVHWYDSALKMTD-YDEGGEFDGMQDEPRYLLLARLAEMYQEGGNNLDADPQRAGDLFTEAADAAMEAMKGRLANQYYMKAEEAWAMME 743
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Zebrafish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:ZFIN;Acc:ZDB-GENE-020916-2]) HSP 1 Score: 466.848 bits (1200), Expect = 6.440e-154 Identity = 267/637 (41.92%), Postives = 370/637 (58.08%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNA-------TCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSC-AVSTDSCSL-----RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ + + DP+ F L E+ TE+ RY Y +IT W D+ +K+ + F +GAMRECFR KK+S F H ++WK A N+V+KRYME V+R VYFEDV LQM+AKLW EEFNR K+VDI++M ++E + RP PL+HLEH+IEG Y KYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHTS +G+GNLG RGMALFFHSH+CN +C ++GL RFDL+P+E+ QL + +++T+ S R S L+ L E + D + D+ I C G V G+ + +N + SQN + + R + D + E + +R+HIHRPSC AV + + ++G+SILG++H + HE GRF ++ DEP + + +YH + AA +EAI+ + +L L P +L ++P E KG+ +L +AA AG RPS++ +A A D DW+ +HW + ++ D DE GEFD D P Y++ AR+A M++ GG LD D +R+ +L++EA D A AMKGRLA++YY +EE + ME
Sbjct: 92 WKHAIEKAKAMPDPWAEFHLEEMETERCTRYRYSAITGEWAKDEIFIKVSSQTFGKGAMRECFRAKKLSNFSHSHNWKSASNYVAKRYMETVDRSVYFEDVRLQMEAKLWGEEFNRHR-PPKQVDIMQMCVVEMTTRPGSPLFHLEHYIEGKYTKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTSKGTDFGDGNLGVRGMALFFHSHLCNKICRSMGLTRFDLSPAEIAQLDCTNKLLQSAKTVLRGFEEQCGSPRVRTTSLGHMPVLLSRLSETSSVDESSDTDS-IPCSPLSMG-----------VSVGRSPMGWSF-----MNEMNETHRSQNTEQQDSENGGDSGYPSEKRSEGDPVEHHGQLTEEKWSFYHSSRSHIHRPSCVAVEVERLNALLLEKKIGKSILGKVHLAMVRYHEAGRFCEK---DEPWDQISAMYHLETAAMCGELEAIVALGQCYLQL-PHHILPEIELEPSEENSQKGFRFLLQAAEAGDRPSMILVARAFDTGLKLPSDRAMDWTEAVHWYDSALKMTD-YDEGGEFDGMQDEPRYLLLARLAEMYQEGGNNLDADPQRAGDLFTEAADAAMEAMKGRLANQYYMKAEEAWAMME 705
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Zebrafish
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2]) HSP 1 Score: 71.2478 bits (173), Expect = 3.018e-12 Identity = 72/252 (28.57%), Postives = 110/252 (43.65%), Query Frame = 3
Query: 408 SWKTDKAIVKME---KEPFNRGAMRECFRLKKISTFHGNDWKRAGN-FVSKRYME---NVEREVYFEDVCLQMDAKLWAEEFNRQPGVKK---EVDIVRMSIIEFSDR----------PDKPLYHLEHFIEGNYIKYNSNSG---FVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNG-----YGNGNLGPRGMALFFHSHICNNVCEALGLA---RFDLAPSELK-QLQSSRGSS 1067
SW K+E KE G R LK + T+ D + G+ ++ K ++ N + +Y E+ L L E +Q +K + +R I +S R + +E I G++ K+N+N+G + T AFSH+T+E + EL+V+D+QGVG++ TDP + S G +G NLG + F H CN+ C L L R D P +L Q S G S
Sbjct: 342 SWAQRGLCAKIEFLSKEEMGGGLRRA---LKVLCTWSEYDILKPGHLYIVKSFLPEVVNTWQTIYREETVLH----LCLREIQQQRAAQKLTFAFNQIRPKTIPYSPRFLEVFLLYCHSAGQWFAIEECITGDFRKFNNNNGDEIVPTNLLEETMLAFSHWTYEYTRGELLVLDLQGVGEILTDPSVIKSGEKGSYDMIFGPANLGDDAIRNFRAKHHCNSCCRKLKLPDLKRNDYTPDKLTLQHDPSEGPS 586
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Zebrafish
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2]) HSP 1 Score: 70.8626 bits (172), Expect = 6.429e-12 Identity = 72/252 (28.57%), Postives = 110/252 (43.65%), Query Frame = 3
Query: 408 SWKTDKAIVKME---KEPFNRGAMRECFRLKKISTFHGNDWKRAGN-FVSKRYME---NVEREVYFEDVCLQMDAKLWAEEFNRQPGVKK---EVDIVRMSIIEFSDR----------PDKPLYHLEHFIEGNYIKYNSNSG---FVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNG-----YGNGNLGPRGMALFFHSHICNNVCEALGLA---RFDLAPSELK-QLQSSRGSS 1067
SW K+E KE G R LK + T+ D + G+ ++ K ++ N + +Y E+ L L E +Q +K + +R I +S R + +E I G++ K+N+N+G + T AFSH+T+E + EL+V+D+QGVG++ TDP + S G +G NLG + F H CN+ C L L R D P +L Q S G S
Sbjct: 1508 SWAQRGLCAKIEFLSKEEMGGGLRRA---LKVLCTWSEYDILKPGHLYIVKSFLPEVVNTWQTIYREETVLH----LCLREIQQQRAAQKLTFAFNQIRPKTIPYSPRFLEVFLLYCHSAGQWFAIEECITGDFRKFNNNNGDEIVPTNLLEETMLAFSHWTYEYTRGELLVLDLQGVGEILTDPSVIKSGEKGSYDMIFGPANLGDDAIRNFRAKHHCNSCCRKLKLPDLKRNDYTPDKLTLQHDPSEGPS 1752
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Zebrafish
Match: trpm7 (transient receptor potential cation channel, subfamily M, member 7 [Source:ZFIN;Acc:ZDB-GENE-021115-2]) HSP 1 Score: 70.4774 bits (171), Expect = 6.606e-12 Identity = 72/252 (28.57%), Postives = 110/252 (43.65%), Query Frame = 3
Query: 408 SWKTDKAIVKME---KEPFNRGAMRECFRLKKISTFHGNDWKRAGN-FVSKRYME---NVEREVYFEDVCLQMDAKLWAEEFNRQPGVKK---EVDIVRMSIIEFSDR----------PDKPLYHLEHFIEGNYIKYNSNSG---FVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNG-----YGNGNLGPRGMALFFHSHICNNVCEALGLA---RFDLAPSELK-QLQSSRGSS 1067
SW K+E KE G R LK + T+ D + G+ ++ K ++ N + +Y E+ L L E +Q +K + +R I +S R + +E I G++ K+N+N+G + T AFSH+T+E + EL+V+D+QGVG++ TDP + S G +G NLG + F H CN+ C L L R D P +L Q S G S
Sbjct: 1523 SWAQRGLCAKIEFLSKEEMGGGLRRA---LKVLCTWSEYDILKPGHLYIVKSFLPEVVNTWQTIYREETVLH----LCLREIQQQRAAQKLTFAFNQIRPKTIPYSPRFLEVFLLYCHSAGQWFAIEECITGDFRKFNNNNGDEIVPTNLLEETMLAFSHWTYEYTRGELLVLDLQGVGEILTDPSVIKSGEKGSYDMIFGPANLGDDAIRNFRAKHHCNSCCRKLKLPDLKRNDYTPDKLTLQHDPSEGPS 1767
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Xenopus
Match: neu4 (neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB-GENE-959717]) HSP 1 Score: 447.588 bits (1150), Expect = 2.804e-146 Identity = 263/654 (40.21%), Postives = 381/654 (58.26%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVH-----QSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKF--LQFQVSSPDSGYDYDEDICLNLAEDLSASQNATC-----------EHNLKKKARFKFDSSNSNDLKKGEDSLDAY----MNRNHIHRPSCA------VSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSD--PDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ ++ + DP+ F L ++ TE IR+ Y++++ W D ++KM + F RGAMREC+R KK+S F H WK A N+VSKRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DRP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVD+QGVGDLYTDPQIHT +G+GNLG RGMALFFHSH CN +C+++GL FD++ E L + T++T+ S +R++ S+P L+ L E+ +D + D + L ++F + + + +E+ L+ D ++ C EH + R +F+S + + G+ S++ + +R H+HRPSC ++ ++G+SILG++H + HE GRF ++ D+ + E+ ++H + AA +EAI+ + + P +L ++Q + + KG+ YL AA AG RPS++ +A A D + GSD DW + W + + D DE GE+D T D P Y++ AR A M TGG+ L KD +RS +LY+EA + A AMKGRLA++YY+ +EE + ME
Sbjct: 83 WKHAIQKAKQMPDPWAEFHLEDIETEHAIRHRYNAVSGQWVQDDVLIKMASQAFGRGAMRECYRTKKLSNFSHKQQWKSAYNYVSKRYLETVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIMQMCIIEMKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDVQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFDISAKEKAVLDNCSKMLQTAQTVVRGIEEKCGSNRVRTMSGSRP------PLLSRLSENSGDDMS---DMAFDSLPSSPSPVTPHGHRFDSHGWPIFNEVDNLLNEENNNLDNHRDSENGGDSGCPSEKRSESDELEHRIHNVGRRRFESESEDSF--GKVSVEKWNQFHASRVHVHRPSCVAFEVERLNALELEKKIGKSILGKVHLAMVRYHEGGRFCEK---DQEWDQESAIFHLEHAAHCGELEAIIGLGLMY-SQSPHHILTDVSVQDTEDNRIKGFNYLLMAAEAGDRPSMIHVARAFDTGVNL--GSDRIKDWQEALFWYDSALNMTD-YDEGGEYDGTQDEPKYLLLAREAEMLLTGGFNLQKDPQRSGDLYTEAAEAAMEAMKGRLANQYYQKAEEAWACME 717
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Xenopus
Match: neu4 (neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB-GENE-959717]) HSP 1 Score: 446.432 bits (1147), Expect = 3.966e-145 Identity = 265/674 (39.32%), Postives = 382/674 (56.68%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVH-----QSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKF--LQFQVSSPDSGYDYDEDICLNLAEDLSASQNATC-----------EHNLKKKARFKFDSSNSNDLKKGEDSLDAYM---------------------NRNHIHRPSCA------VSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSD--PDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME*KF 2168
W+ ++ + DP+ F L ++ TE IR+ Y++++ W D ++KM + F RGAMREC+R KK+S F H WK A N+VSKRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DRP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVD+QGVGDLYTDPQIHT +G+GNLG RGMALFFHSH CN +C+++GL FD++ E L + T++T+ S +R++ S+P L+ L E+ +D + D + L ++F + + + +E+ L+ D ++ C EH + R +F+S + + K + AY+ +R H+HRPSC ++ ++G+SILG++H + HE GRF ++ D+ + E+ ++H + AA +EAI+ + + P +L ++Q + + KG+ YL AA AG RPS++ +A A D + GSD DW + W + + D DE GE+D T D P Y++ AR A M TGG+ L KD +RS +LY+EA + A AMKGRLA++YY+ +EE + ME K+
Sbjct: 100 WKHAIQKAKQMPDPWAEFHLEDIETEHAIRHRYNAVSGQWVQDDVLIKMASQAFGRGAMRECYRTKKLSNFSHKQQWKSAYNYVSKRYLETVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIMQMCIIEMKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDVQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFDISAKEKAVLDNCSKMLQTAQTVVRGIEEKCGSNRVRTMSGSRP------PLLSRLSENSGDDMS---DMAFDSLPSSPSPVTPHGHRFDSHGWPIFNEVDNLLNEENNNLDNHRDSENGGDSGCPSEKRSESDELEHRIHNVGRRRFESESEDSFGKSKGVNKAYVILKNSPRSKLVSVEKWNQFHASRVHVHRPSCVAFEVERLNALELEKKIGKSILGKVHLAMVRYHEGGRFCEK---DQEWDQESAIFHLEHAAHCGELEAIIGLGLMY-SQSPHHILTDVSVQDTEDNRIKGFNYLLMAAEAGDRPSMIHVARAFDTGVNL--GSDRIKDWQEALFWYDSALNMTD-YDEGGEYDGTQDEPKYLLLAREAEMLLTGGFNLQKDPQRSGDLYTEAAEAAMEAMKGRLANQYYQKAEEAWACMEEKY 756
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Xenopus
Match: neu4 (neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB-GENE-959717]) HSP 1 Score: 446.047 bits (1146), Expect = 5.706e-145 Identity = 265/674 (39.32%), Postives = 382/674 (56.68%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRN-RNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVH-----QSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKF--LQFQVSSPDSGYDYDEDICLNLAEDLSASQNATC-----------EHNLKKKARFKFDSSNSNDLKKGEDSLDAYM---------------------NRNHIHRPSCA------VSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSD--PDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME*KF 2168
W+ ++ + DP+ F L ++ TE IR+ Y++++ W D ++KM + F RGAMREC+R KK+S F H WK A N+VSKRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DRP KPL+HLEH+IEG YIKYNSNSGFV D N R TPQAFSHFTFERSGH+LIVVD+QGVGDLYTDPQIHT +G+GNLG RGMALFFHSH CN +C+++GL FD++ E L + T++T+ S +R++ S+P L+ L E+ +D + D + L ++F + + + +E+ L+ D ++ C EH + R +F+S + + K + AY+ +R H+HRPSC ++ ++G+SILG++H + HE GRF ++ D+ + E+ ++H + AA +EAI+ + + P +L ++Q + + KG+ YL AA AG RPS++ +A A D + GSD DW + W + + D DE GE+D T D P Y++ AR A M TGG+ L KD +RS +LY+EA + A AMKGRLA++YY+ +EE + ME K+
Sbjct: 100 WKHAIQKAKQMPDPWAEFHLEDIETEHAIRHRYNAVSGQWVQDDVLIKMASQAFGRGAMRECYRTKKLSNFSHKQQWKSAYNYVSKRYLETVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIMQMCIIEMKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDVQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFDISAKEKAVLDNCSKMLQTAQTVVRGIEEKCGSNRVRTMSGSRP------PLLSRLSENSGDDMS---DMAFDSLPSSPSPVTPHGHRFDSHGWPIFNEVDNLLNEENNNLDNHRDSENGGDSGCPSEKRSESDELEHRIHNVGRRRFESESEDSFGKSKGVNKAYVILKNSPRSKLVSVEKWNQFHASRVHVHRPSCVAFEVERLNALELEKKIGKSILGKVHLAMVRYHEGGRFCEK---DQEWDQESAIFHLEHAAHCGELEAIIGLGLMY-SQSPHHILTDVSVQDTEDNRIKGFNYLLMAAEAGDRPSMIHVARAFDTGVNL--GSDRIKDWQEALFWYDSALNMTD-YDEGGEYDGTQDEPKYLLLAREAEMLLTGGFNLQKDPQRSGDLYTEAAEAAMEAMKGRLANQYYQKAEEAWACMEEKY 756
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Xenopus
Match: neu4 (neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB-GENE-959717]) HSP 1 Score: 446.047 bits (1146), Expect = 6.725e-145 Identity = 265/674 (39.32%), Postives = 382/674 (56.68%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVH-----QSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKF--LQFQVSSPDSGYDYDEDICLNLAEDLSASQNATC-----------EHNLKKKARFKFDSSNSNDLKKGEDSLDAYM---------------------NRNHIHRPSCA------VSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSD--PDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME*KF 2168
W+ ++ + DP+ F L ++ TE IR+ Y++++ W D ++KM + F RGAMREC+R KK+S F H WK A N+VSKRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DRP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVD+QGVGDLYTDPQIHT +G+GNLG RGMALFFHSH CN +C+++GL FD++ E L + T++T+ S +R++ S+P L+ L E+ +D + D + L ++F + + + +E+ L+ D ++ C EH + R +F+S + + K + AY+ +R H+HRPSC ++ ++G+SILG++H + HE GRF ++ D+ + E+ ++H + AA +EAI+ + + P +L ++Q + + KG+ YL AA AG RPS++ +A A D + GSD DW + W + + D DE GE+D T D P Y++ AR A M TGG+ L KD +RS +LY+EA + A AMKGRLA++YY+ +EE + ME K+
Sbjct: 100 WKHAIQKAKQMPDPWAEFHLEDIETEHAIRHRYNAVSGQWVQDDVLIKMASQAFGRGAMRECYRTKKLSNFSHKQQWKSAYNYVSKRYLETVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIMQMCIIEMKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDVQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFDISAKEKAVLDNCSKMLQTAQTVVRGIEEKCGSNRVRTMSGSRP------PLLSRLSENSGDDMS---DMAFDSLPSSPSPVTPHGHRFDSHGWPIFNEVDNLLNEENNNLDNHRDSENGGDSGCPSEKRSESDELEHRIHNVGRRRFESESEDSFGKSKGVNKAYVILKNSPRSKLVSVEKWNQFHASRVHVHRPSCVAFEVERLNALELEKKIGKSILGKVHLAMVRYHEGGRFCEK---DQEWDQESAIFHLEHAAHCGELEAIIGLGLMY-SQSPHHILTDVSVQDTEDNRIKGFNYLLMAAEAGDRPSMIHVARAFDTGVNL--GSDRIKDWQEALFWYDSALNMTD-YDEGGEYDGTQDEPKYLLLAREAEMLLTGGFNLQKDPQRSGDLYTEAAEAAMEAMKGRLANQYYQKAEEAWACMEEKY 756
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Xenopus
Match: neu4 (neuraminidase 4 (sialidase) [Source:Xenbase;Acc:XB-GENE-959717]) HSP 1 Score: 410.609 bits (1054), Expect = 2.968e-132 Identity = 253/650 (38.92%), Postives = 365/650 (56.15%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVH-----QSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYMNRNH-------------IHRPSCA------VSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSD--PDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ ++ + DP+ F L ++ TE IR+ Y++++ W D ++KM + + ++ F KK+S F H WK A N+VSKRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DRP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVD+QGVGDLYTDPQIHT +G+GNLG RGMALFFHSH CN +C+++GL FD++ E L + T++T+ S +R++ S+P L+ L E+ +D + D + L SSP + I + L+ N H + + DS ++ + D L+ ++ +H +HRPSC ++ ++G+SILG++H + HE GRF ++ D+ + E+ ++H + AA +EAI+ + + P +L ++Q + + KG+ YL AA AG RPS++ +A A D + GSD DW + W + + D DE GE+D T D P Y++ AR A M TGG+ L KD +RS +LY+EA + A AMKGRLA++YY+ +EE + ME
Sbjct: 83 WKHAIQKAKQMPDPWAEFHLEDIETEHAIRHRYNAVSGQWVQDDVLIKMASQVELKSSLN-LFCRKKLSNFSHKQQWKSAYNYVSKRYLETVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIMQMCIIEMKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDVQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNRICKSMGLTPFDISAKEKAVLDNCSKMLQTAQTVVRGIEEKCGSNRVRTMSGSRP------PLLSRLSENSGDDMS---DMAFDSLP------------------SSPSPVTPHGWPIFNEVDNLLNEENNNLDNH---RDSENGGDSGCPSEKRSESDELEHRVSESHVEKWNQFHASRVHVHRPSCVAFEVERLNALELEKKIGKSILGKVHLAMVRYHEGGRFCEK---DQEWDQESAIFHLEHAAHCGELEAIIGLGLMY-SQSPHHILTDVSVQDTEDNRIKGFNYLLMAAEAGDRPSMIHVARAFDTGVNL--GSDRIKDWQEALFWYDSALNMTD-YDEGGEYDGTQDEPKYLLLAREAEMLLTGGFNLQKDPQRSGDLYTEAAEAAMEAMKGRLANQYYQKAEEAWACME 693
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Mouse
Match: Eef2k (eukaryotic elongation factor-2 kinase [Source:MGI Symbol;Acc:MGI:1195261]) HSP 1 Score: 452.21 bits (1162), Expect = 4.979e-148 Identity = 275/680 (40.44%), Postives = 388/680 (57.06%), Query Frame = 3
Query: 237 KSESMSNDDSIKHLKVPKLWQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRN-RNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQL-QSSR----GSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQV----------------------SSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAY--MNRNHIHRP-SCAVSTDSCSL-------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
K+E S + W+ + + DP+ F L ++ TE R+ Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H WK A N+V+KRY+E V+R VYFEDV LQM+AKLW E++NR K+VDI++M IIE DRP +PL+HLEH+IEG YIKYNSNSGFV D N R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFF+SH CN +C+++GL FDL+P E + QS+R +I T S +R+L SS+P L+ L E+ +++ + + + + QK L + V +S DSGY ++ L+ E EH R + +S + G ++ + +N + +H P AV+ + L ++G+S+LG++H + HE GRF ++ DE + E+ ++H + AA L +EAI+ + + L P +L +++ E K KG+ YL KAA AG R S++ +A A D + DWS +HW +ET D DE GE+D D P Y + AR A M TGG+GLDK+ +RS +LY++A + A AMKGRLA++YYE +EE + +ME
Sbjct: 65 KTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHK-PPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPREQDAVNQSTRLLQSAKTILRGTEEKCGSPRIRTLSSSRP------PLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPR--------EHGHSNGNR-RHESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEK---DEEWDRESAIFHLEHAADLGELEAIVGLGLMYSQL-PHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTD-CDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Mouse
Match: Eef2k (eukaryotic elongation factor-2 kinase [Source:MGI Symbol;Acc:MGI:1195261]) HSP 1 Score: 452.21 bits (1162), Expect = 4.979e-148 Identity = 275/680 (40.44%), Postives = 388/680 (57.06%), Query Frame = 3
Query: 237 KSESMSNDDSIKHLKVPKLWQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRN-RNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQL-QSSR----GSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQV----------------------SSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAY--MNRNHIHRP-SCAVSTDSCSL-------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
K+E S + W+ + + DP+ F L ++ TE R+ Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H WK A N+V+KRY+E V+R VYFEDV LQM+AKLW E++NR K+VDI++M IIE DRP +PL+HLEH+IEG YIKYNSNSGFV D N R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFF+SH CN +C+++GL FDL+P E + QS+R +I T S +R+L SS+P L+ L E+ +++ + + + + QK L + V +S DSGY ++ L+ E EH R + +S + G ++ + +N + +H P AV+ + L ++G+S+LG++H + HE GRF ++ DE + E+ ++H + AA L +EAI+ + + L P +L +++ E K KG+ YL KAA AG R S++ +A A D + DWS +HW +ET D DE GE+D D P Y + AR A M TGG+GLDK+ +RS +LY++A + A AMKGRLA++YYE +EE + +ME
Sbjct: 65 KTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHK-PPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPREQDAVNQSTRLLQSAKTILRGTEEKCGSPRIRTLSSSRP------PLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPR--------EHGHSNGNR-RHESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEK---DEEWDRESAIFHLEHAADLGELEAIVGLGLMYSQL-PHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTD-CDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Mouse
Match: Eef2k (eukaryotic elongation factor-2 kinase [Source:MGI Symbol;Acc:MGI:1195261]) HSP 1 Score: 452.21 bits (1162), Expect = 4.979e-148 Identity = 275/680 (40.44%), Postives = 388/680 (57.06%), Query Frame = 3
Query: 237 KSESMSNDDSIKHLKVPKLWQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRN-RNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQL-QSSR----GSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQV----------------------SSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAY--MNRNHIHRP-SCAVSTDSCSL-------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
K+E S + W+ + + DP+ F L ++ TE R+ Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H WK A N+V+KRY+E V+R VYFEDV LQM+AKLW E++NR K+VDI++M IIE DRP +PL+HLEH+IEG YIKYNSNSGFV D N R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFF+SH CN +C+++GL FDL+P E + QS+R +I T S +R+L SS+P L+ L E+ +++ + + + + QK L + V +S DSGY ++ L+ E EH R + +S + G ++ + +N + +H P AV+ + L ++G+S+LG++H + HE GRF ++ DE + E+ ++H + AA L +EAI+ + + L P +L +++ E K KG+ YL KAA AG R S++ +A A D + DWS +HW +ET D DE GE+D D P Y + AR A M TGG+GLDK+ +RS +LY++A + A AMKGRLA++YYE +EE + +ME
Sbjct: 65 KTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHK-PPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPREQDAVNQSTRLLQSAKTILRGTEEKCGSPRIRTLSSSRP------PLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPR--------EHGHSNGNR-RHESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEK---DEEWDRESAIFHLEHAADLGELEAIVGLGLMYSQL-PHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTD-CDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Mouse
Match: Eef2k (eukaryotic elongation factor-2 kinase [Source:MGI Symbol;Acc:MGI:1195261]) HSP 1 Score: 109.768 bits (273), Expect = 4.712e-27 Identity = 63/134 (47.01%), Postives = 84/134 (62.69%), Query Frame = 3
Query: 1758 EKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
E K KG+ YL KAA AG R S++ +A A D + DWS +HW +ET D DE GE+D D P Y + AR A M TGG+GLDK+ +RS +LY++A + A AMKGRLA++YYE +EE + +ME
Sbjct: 52 ENKTKGFDYLLKAAEAGDRHSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTD-CDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 184
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Mouse
Match: Eef2k (eukaryotic elongation factor-2 kinase [Source:MGI Symbol;Acc:MGI:1195261]) HSP 1 Score: 86.6557 bits (213), Expect = 1.542e-19 Identity = 50/121 (41.32%), Postives = 67/121 (55.37%), Query Frame = 3
Query: 1716 PRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAG 2078
P +L +++ E K KG+ YL KAA AG R S++ +A A D + DWS +HW +ET D DE GE+D D P Y + AR A M TGG+GLDK+ +RS E+ S G
Sbjct: 13 PHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTD-CDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRS-EMESHVG 131
BLAST of Eukaryotic elongation factor 2 kinase vs. UniProt/SwissProt
Match: sp|O00418|EF2K_HUMAN (Eukaryotic elongation factor 2 kinase OS=Homo sapiens OX=9606 GN=EEF2K PE=1 SV=2) HSP 1 Score: 460.685 bits (1184), Expect = 2.030e-150 Identity = 275/654 (42.05%), Postives = 388/654 (59.33%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSE-------LKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQV-SSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKK----KARFKFDSSNSNDLKKGEDSLDA----------YMNRNHIHRP-SCAVSTDSCSL-------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ ++ + DP+ F L ++ TE+ R+ Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H WK A N+V+KRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DRP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFF+SH CN +CE++GLA FDL+P E K LQS++ +I T S +R+L S+P L+ L E+ +++ + + + + QK L + V S D+ D D N E ++ + + + R S ++ + EDSL + +N + +H P + AV+ + L ++G+SILG++H + HE GRF ++ E + E+ ++H + AA+L +EAI+ + + L P +L +++ E K KG+ YL KAA AG R S++ +A A D Q+ DW +HW +E D DE GE+D D P Y++ AR A M TGGYGL+KD +RS +LY++A + A AMKGRLA++YY+ +EE + +ME
Sbjct: 85 WKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAK--TILRGTEEKCGSPQVRTLSGSRP------PLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDNMASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKYESDEDSLGSSGRVCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFCEKG---EEWDQESAVFHLEHAANLGELEAIVGLGLMYSQL-PHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTD-CDEGGEYDGMQDEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQME 724
BLAST of Eukaryotic elongation factor 2 kinase vs. UniProt/SwissProt
Match: sp|P70531|EF2K_RAT (Eukaryotic elongation factor 2 kinase OS=Rattus norvegicus OX=10116 GN=Eef2k PE=1 SV=1) HSP 1 Score: 454.136 bits (1167), Expect = 6.553e-148 Identity = 277/683 (40.56%), Postives = 390/683 (57.10%), Query Frame = 3
Query: 234 LKSESMSNDDSIKHLKVPKLWQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSE-------LKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQV----------------------SSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAY--MNRNHIHRP-SCAVSTDSCSL-------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
LK+E S + W+ + + DP+ F L ++ TE R+ Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H WK A N+V+KRY+E V+R VYFEDV LQM+AKLW EE+NR K+VDI++M IIE DR +PL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFF+SH CN +C+++GLA FDL+P E K LQS++ +I T S +R+L S+P L+ L E+ +++ + + + + QK L + V +S DSGY ++ L+ E + N ++ DS S+ G ++ + +N + +H P AV+ + L ++G+S+LG++H + HE GRF ++ DE + E+ ++H + AA L +EAI+ + + L P +L +++ E K KG+ YL KAA AG R S++ +A A D + DWS +HW +ET D DE GE+D D P Y + AR A M TGG+GLDK+ +RS +LY++A + A AMKGRLA++YYE +EE + +ME
Sbjct: 64 LKTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQHWKGASNYVAKRYLEPVDRSVYFEDVQLQMEAKLWGEEYNRHK-PPKQVDIMQMCIIELKDRQGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLAPFDLSPREQDAVNQSTKLLQSAK--TILRGTEEKCGSPRIRTLSGSRP------PLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPREHGHS-----NGNRRPESDEDSLGSS----GRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEK---DEEWDQESAIFHLEHAADLGELEAIVGLGLMYSQL-PHHILADVSLEETEENKTKGFDYLLKAAEAGDRQSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTD-CDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
BLAST of Eukaryotic elongation factor 2 kinase vs. UniProt/SwissProt
Match: sp|O08796|EF2K_MOUSE (Eukaryotic elongation factor 2 kinase OS=Mus musculus OX=10090 GN=Eef2k PE=1 SV=1) HSP 1 Score: 452.21 bits (1162), Expect = 3.483e-147 Identity = 275/680 (40.44%), Postives = 388/680 (57.06%), Query Frame = 3
Query: 237 KSESMSNDDSIKHLKVPKLWQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRN-RNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQL-QSSR----GSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQV----------------------SSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAY--MNRNHIHRP-SCAVSTDSCSL-------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
K+E S + W+ + + DP+ F L ++ TE R+ Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H WK A N+V+KRY+E V+R VYFEDV LQM+AKLW E++NR K+VDI++M IIE DRP +PL+HLEH+IEG YIKYNSNSGFV D N R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFF+SH CN +C+++GL FDL+P E + QS+R +I T S +R+L SS+P L+ L E+ +++ + + + + QK L + V +S DSGY ++ L+ E EH R + +S + G ++ + +N + +H P AV+ + L ++G+S+LG++H + HE GRF ++ DE + E+ ++H + AA L +EAI+ + + L P +L +++ E K KG+ YL KAA AG R S++ +A A D + DWS +HW +ET D DE GE+D D P Y + AR A M TGG+GLDK+ +RS +LY++A + A AMKGRLA++YYE +EE + +ME
Sbjct: 65 KTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHK-PPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPREQDAVNQSTRLLQSAKTILRGTEEKCGSPRIRTLSSSRP------PLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPR--------EHGHSNGNR-RHESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEK---DEEWDRESAIFHLEHAADLGELEAIVGLGLMYSQL-PHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTD-CDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQME 723
BLAST of Eukaryotic elongation factor 2 kinase vs. UniProt/SwissProt
Match: sp|O01991|EF2K_CAEEL (Eukaryotic elongation factor 2 kinase OS=Caenorhabditis elegans OX=6239 GN=efk-1 PE=1 SV=1) HSP 1 Score: 368.237 bits (944), Expect = 1.673e-114 Identity = 262/726 (36.09%), Postives = 372/726 (51.24%), Query Frame = 3
Query: 261 DSIKHLKVPKLWQSLARRTLM-LSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSEL-----------KQLQS---------SRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNED--SNEQIDNVIECLTQCAGDK--------------NEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSN-------------DLKKGE-------DSLDAYMNRNHIHRPSCAVSTDSCSLRMGE---SILGEIHHEISNMHEIGRFAD------------RNQLDEPINW--EAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTI---------------------QPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTV-----ETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSE 2138
D + K+ + W+ ARR DP+ F + E P ++ RY Y +I K W D V++ + F RGAMREC+RLKK S HG + N+V+KRY+ V+R V F+DV LQMDAKLWAEE+NR KK +DIV+M +IE D PLYHLEHFIEG YIKYNSNSGFV + R TPQAFSHFTFERSGH+++VVDIQGVGDLYTDPQIHT YG+GNLG RGMALFFHSH CN++CE + L+ F+L+P E+ KQ +S +R + I+SE + V + LR K +L + D+ + NED E I V + C+ D+ N QK++ + +S+ SG D SAS+ C R + DS S+ D +K E S+ A + + + + + D ++ S+LG+IH ++S HE+GRF + N PI + ++ ++H D+A +EA+L A+ LGL P +LLK T+ +P ++F G + AA G + +++ +A A + Q D+ + W +R V E +D F S + + A+MA M++ GGYGL++D ER+ L++EA + A AM G+LA+KYYE +E
Sbjct: 59 DPLHVRKLMETWRKAARRARTNYIDPWDEFNIHEYPVQRAKRYRYSAIRKQWTEDIVDVRLHPDSFARGAMRECYRLKKCSK-HGTSQDWSSNYVAKRYICQVDRRVLFDDVRLQMDAKLWAEEYNRYNPPKK-IDIVQMCVIEMIDVKGSPLYHLEHFIEGKYIKYNSNSGFVSNAARLTPQAFSHFTFERSGHQMMVVDIQGVGDLYTDPQIHTVVGTDYGDGNLGTRGMALFFHSHRCNDICETMDLSNFELSPPEIEATEVAMEVAAKQKKSCIVPPTVFEARRNRISSECVHVEHGISMDQLRKRK---TLNQSSTDLSAKSHNEDCVCPECIPVVEQLCEPCSEDEEDEEEDYPRSEKSGNSQKSRRSRMSISTRSSG-------------DESASRPRKCGFVDLNSLRQRHDSFRSSVGTYSMNSSRQTRDTEKDEFWKVLRKQSVPANILSLQLQQMAANLENDEDVPQVTGHQFSVLGQIHIDLSRYHELGRFVEVDSEHKEMLEGSENDARVPIKYDKQSAIFHLDIARKCGILEAVLTSAHIVLGL-PHELLKEVTVDDLFPNGFGEQENGIRADKGQKPCDLEEF-GSDLMEIAAEMGDKGAMLYMAHAYETGQHLGPNRRTDYKKSIDWYQRVVGFQEEEELDSDCGKTTFSSFAPLTRHEILAKMAEMYKEGGYGLNQDFERAYGLFNEAAEAAMEAMNGKLANKYYEKAE 764
BLAST of Eukaryotic elongation factor 2 kinase vs. UniProt/SwissProt
Match: sp|Q54DK4|AK1_DICDI (Alpha-protein kinase 1 OS=Dictyostelium discoideum OX=44689 GN=ak1 PE=3 SV=1) HSP 1 Score: 198.364 bits (503), Expect = 2.646e-51 Identity = 104/236 (44.07%), Postives = 146/236 (61.86%), Query Frame = 3
Query: 366 TEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGNDWKRAGNFVSKRYME-NVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSI 1070
TE+VIR+ +D+ W IV E PF GAMR+ FR+K +S + V+K + + N +R VYF+DV +Q +K AE FN + K++D V ++E +R KP +E+FIEG Y K+N+N G+ +D +RNTPQAFSHF++E SG +LIVVDIQGVGD+YTDPQIH++ G+G GNLG G+ FF +H CN +C LGL+ + P+ + R SI
Sbjct: 983 TERVIRHRFDAKLGKWVQTATIVITEPTPFAEGAMRKAFRMKDLSA-----EGPSSQMVAKLFKDSNEDRMVYFKDVEMQTYSKEIAERFNLK-SPPKKIDFVPAFVMELVERQGKPFCAVEYFIEGKYEKHNNNFGYKNDYDRNTPQAFSHFSYEDSGCQLIVVDIQGVGDVYTDPQIHSADGQGFGKGNLGIEGIKRFFSTHQCNPICHYLGLSSVNPKPANDESGTMPRPPSI 1212
BLAST of Eukaryotic elongation factor 2 kinase vs. TrEMBL
Match: A0A2T7PWR4 (Eukaryotic elongation factor 2 kinase OS=Pomacea canaliculata OX=400727 GN=C0Q70_00477 PE=3 SV=1) HSP 1 Score: 507.294 bits (1305), Expect = 1.027e-166 Identity = 281/627 (44.82%), Postives = 390/627 (62.20%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLN-LAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSCA-VSTDS---CSLRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W + DP+ F +++ E RY Y+++ K+W D +VKME +PF RGAMR+CFRLKK+STF DWK A N+V+K Y+ENVER+VYFEDV LQM+AKLW EE+NR KK VDI +M ++EF +RP PL+HLEHFIEG YIKYNSNSGFV+D+ R TPQAFSHFTFERSGH+LIVVD+QGVGDLYTDPQIHT GYG+GNLGP+GMALFFHSH+CN++C++L L FDLAP+ +A H SK + + E ++ E ID LT G ++ ++ S G+D D+ L+ +ED S +A + ++R+ +S NS ++ + + + RPSC D +LR+GES+LG+IHHE++ HEIGRF+ + + ++WEAVL+HE+ AA L +EAI MA +LGL PRD+L CT++ E G Y+ +AA AG R +I+ +A A D + W +HW +R VET D+ DE G +DST ++P Y++ +R A M++ GGYGLDKD + + +LY++A + AT AMKGRLA+K+++L+EE + E++
Sbjct: 90 WLRAFHKARKAKDPWAEFHINDYDCEVCTRYRYNALKKTWVKDDVLVKMETKPFTRGAMRQCFRLKKLSTFCTLDWKHAQNYVAKNYLENVERDVYFEDVKLQMEAKLWGEEYNRHNPPKK-VDIFQMYVLEFKNRPGSPLFHLEHFIEGEYIKYNSNSGFVEDKLRLTPQAFSHFTFERSGHKLIVVDVQGVGDLYTDPQIHTMDGEGYGDGNLGPKGMALFFHSHMCNSICKSLHLTPFDLAPT----------------VVATHNDY------ISKQKKYATTRVRGKEEMCISASYKEMID-----LTALLGRQHSSNSQ-------SSVEGFDDDDGSLLSPTSEDEPMSSDAPSP-GMFTRSRYTSESENS---ATEDEERKKFQEAHALSRPSCVNFELDMRKLSNLRIGESVLGQIHHEMAKYHEIGRFSVKEDV---VDWEAVLFHEEHAAQLGVLEAITTMARLYLGL-PRDVLINCTVEQSDENIDVGVDYMLQAAEAGDRSAIIYMAKAFDSGHNLGTRRSQSWEDAVHWYQRAVET-DEHDEGGHYDSTMEDPQYLLLSRQAEMYQQGGYGLDKDPQIAGDLYTQAAEAATEAMKGRLANKFFQLAEEAWAEVD 672
BLAST of Eukaryotic elongation factor 2 kinase vs. TrEMBL
Match: W4Y7D7 (Eukaryotic elongation factor 2 kinase OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1) HSP 1 Score: 478.019 bits (1229), Expect = 2.488e-155 Identity = 275/623 (44.14%), Postives = 369/623 (59.23%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGN-DWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDS-SNSNDLKKGEDSLDAYMNRNHIHRPSCA-----VSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKF-KGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELS 2135
W+ ++ ++DP++ F L +LP + IR+ Y+++ K+W D+ VKM E F GAMRECFR+KK S F + WK +GNFV+KRYME VER+VYF+DV LQMDAK+W EEFNR KK VDI +M+++EF +RP KPL+HLE +IEG YIKYNSNSGFV D+ R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHTS Y GNLG RGMALFF +H CN +C+ L L +FDL SE + + S TI R KP + +DM + + E SN Q+ + + ++ F + SSPD D+ ++++ S ++ ARF+ DS S S L ++ ++ RN HRPSC + G SILG+IH +++ HE+GRFA D N EA LYH A +EAI+ MA L L D+L ++ D E +G Y+ AA AG R +I+ +A A D + W MHW E V T +++DE+G +DST D+P+Y++ ARMA M+R GG LDK+ E++AELY+EA + A AAMKGRL++KYY L+
Sbjct: 75 WKWAFQQVRKMNDPWKEFHLEDLPIDTAIRHRYNAVEKTWVQDEVQVKMGSESFAHGAMRECFRMKKKSNFSKHHQWKNSGNFVAKRYMETVERDVYFQDVRLQMDAKIWGEEFNRHNPPKK-VDIFQMAVLEFMNRPGKPLFHLESYIEGKYIKYNSNSGFVRDEALRKTPQAFSHFTFERSGHKLIVVDIQGVGDLYTDPQIHTSTGTEYNEGNLGMRGMALFFATHACNEICDHLELTQFDLHCSEFTEHEKYVKLQKNSGTICRGTEN-----RVFKPRARPSISPLDMTQFVVFERSNSQMSTGSSVVLSPLAESPPRRISFQELP-SSPD-------DVAMSMSPPPSVLNQFQ-----RRTARFRLDSESESETLSHDDEKRAKFLERNVNHRPSCVNLEVQLRKTMLVTSTGGSILGQIHLDMAKYHEMGRFAPD---DNSRNMEAALYHLRHGADCGVLEAIIAMARICLQL-THDVLTEVSVPSDDEDYMNEGMDYMETAAEAGDRAAILFVARAYDTGHNLGTARTKSWLEAMHWYEEAVNT-EKVDEDGHYDSTMDDPNYLLSARMAEMYRAGGPDLDKNPEKAAELYNEAAEGAIAAMKGRLSNKYYMLA 673
BLAST of Eukaryotic elongation factor 2 kinase vs. TrEMBL
Match: K1RAD5 (Eukaryotic elongation factor 2 kinase OS=Crassostrea gigas OX=29159 GN=CGI_10025610 PE=3 SV=1) HSP 1 Score: 475.322 bits (1222), Expect = 3.924e-154 Identity = 274/629 (43.56%), Postives = 377/629 (59.94%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQ------VSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDS---SNSNDLKKGEDSLDAYMNRNHIHRPSC-AVSTDSCSL---RMGESILGEIHHEISNMHEIGRFADRNQLDEP-INWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELS 2135
W ++ LSDP+ +F + ++ TE IR+ Y+ K+W D+ VKM K+PFNRGAMR+CFRLKKISTF DW A N+V+KRY+E V+R+VYF+DV LQMDAK+W EE+NR KK VDI +M I+EF DRP +PLYHLEHFIEG YIKYNSNSGFVD+ R TPQAFSHFTFERS H LIVVDIQGVGDLYTDPQIHT YG+GNLG +GMALFFHSHICN++C +L L FDL+P E IA H+ LR+ R S + + +CL+ + +FL Q VS + D D ++ ++ S ++ + RF+ S S S+ K+ E+ M + RPSC A+ D L ++G+SILG++HHE++ HE+GRF + DE I+WE+ ++HE+ AA L +EA++ MA +LG R++L C ++P E +G ++ +AA AG R +++ + A + W ++W E+ V+T D DE G+FD T ++PSY + A+ A M+R GG+GLDKD +R+ +LY+EA + A AMKGRLA+KY+ L+
Sbjct: 90 WIMAIKKARDLSDPWASFHIEDIKTEFCIRHRYNPHKKTWTKDEVQVKMMKKPFNRGAMRQCFRLKKISTFSRSGDWSHAQNYVAKRYIEKVDRDVYFQDVRLQMDAKVWGEEYNRHNPPKK-VDIFQMYILEFKDRPGEPLYHLEHFIEGEYIKYNSNSGFVDENLRYTPQAFSHFTFERSAHNLIVVDIQGVGDLYTDPQIHTVGSCEYGDGNLGAKGMALFFHSHICNDICNSLNLTEFDLSPRE----------------IATHKDF-LRAQRKSIMQTKVRG-------------------EIEQCLSLSPSSEKIDITRFLDHQRTCSTGVSDGHTPTDLDSP---SMDDEEPMSVDSPSPSGVPYGVRFRSPSDTDSQSSMTKEEEEEAFNRMAGSQNARPSCVALEKDFRKLMNHKIGDSILGKVHHEMAKYHEVGRFVLGDSKDEKLIDWESAIFHEEHAAELGELEAMVTMAKLYLG-QDREVLVNCVVEPSDEHTNRGVDFMVEAAEAGDRGAMVYMGRAFETGDGLGTLRSVSWEDAVYWYEQAVKTHDN-DEGGQFDCTINDPSYTLMAKQAEMYRQGGHGLDKDPQRAGDLYNEAAEAAMEAMKGRLANKYFALA 676
BLAST of Eukaryotic elongation factor 2 kinase vs. TrEMBL
Match: A0A4D9E4W4 (Eukaryotic elongation factor 2 kinase OS=Platysternon megacephalum OX=55544 GN=DR999_PMT15611 PE=3 SV=1) HSP 1 Score: 476.093 bits (1224), Expect = 4.830e-154 Identity = 274/652 (42.02%), Postives = 378/652 (57.98%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQ-----STPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKA-----RFKFDSSNSNDLKKGEDSLDAYM------------NRNHIHRPSC-AVSTDSCSL-----RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ ++ + DP+ F L ++ TE RY Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H +WK A N+V+KRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDIV+ SIIE +RP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LI+VDIQGVGDLYTDPQIHT +G+GNLG RGMALFFHSH CN +C+++GL FDL+P E L S +++TI S+ +R++ S+P L+ L E+ ++S D + L K L + V S + + L+ D ++ C + R K S+ + + EDSL + +R H+HRPSC AV + ++G+SILG++H + HE GRF ++ D+ + E+ L+H AA +EAI+ + + L P +L T + E + KG+ YL +AA AG RPS++ +A A D + DW +HW + D DE GE+D T D P Y++ AR A M TGG+ L KD +RS ELY+EA + A AMKGRLA++YY+ +EE + +ME
Sbjct: 85 WKHAIQKAKHMPDPWAEFHLEDIETEYATRYRYNAVTGEWVEDEVLIKMASQPFGRGAMRECFRTKKLSNFLHTQNWKGAFNYVAKRYIETVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIVQTSIIEMKNRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIIVDIQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNKICKSMGLTPFDLSPKEKHVLDHSNKLLESAQTIVRGTEEKCGSSRVRTISGSRP------PLLFRLSENSGDES--MSDVAFDSLPSSPSSATPHKMDMLHWPVFSEVDNLVHKDHDHLDNQRDSENGGDSGCPSEKRSDVEDMDHREKGHSNYNRRRESDEDSLGSSARVSVEKWNLYNSSRVHVHRPSCVAVEVQRLNALEFEKKIGKSILGKVHLAMVRYHEAGRFCEK---DQEWDQESALFHLVDAADCGELEAIVGLGLMYSQL-PHHILSEVTSEDTEENQGKGFDYLLRAAEAGDRPSMILVARAYDTGVNLGSNRIQDWKEALHWYNAALNMTD-YDEGGEYDGTQDEPRYLLLAREAEMLMTGGFHLAKDPQRSGELYTEAAEAAIQAMKGRLANQYYQKAEEAWAKME 722
BLAST of Eukaryotic elongation factor 2 kinase vs. TrEMBL
Match: K7FRH3 (Eukaryotic elongation factor 2 kinase OS=Pelodiscus sinensis OX=13735 GN=EEF2K PE=3 SV=1) HSP 1 Score: 475.707 bits (1223), Expect = 6.523e-154 Identity = 277/660 (41.97%), Postives = 385/660 (58.33%), Query Frame = 3
Query: 276 LKVPKLWQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSEL-------KQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATC----EHNLKKKARFKFDSSNSNDLKKG-EDSLDAYM------------NRNHIHRPSC-AVSTDSCSL-----RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
+ + W+ ++ + DP+ F L ++ TE RY Y+++T W D+ ++KM +PF RGAMRECFR KK+S F H +WK A N+V+KRY+E V+R+VYFEDV LQM+AKLW EE+NR K+VDIV+ SIIE +RP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LI+VDIQGVGDLYTDPQIHT +G+GNLG RGMALFFHSH CN +C+++GL FDL+P E KQL+S++ +I T S+ +R++ S+P L+ L E+ ++S D + L K LQ+ V + + + L+ D ++ C +L+ SN N ++ EDSL + +R HIHRPSC AV + ++G+SILG++H + HE GRF ++ D+ + E+ L+H AA +EAI+ + + L P +L T + E + KG+ YL +AA AG RPS++ +A A D + DW+ +HW + D DE GE+D T D P Y++ AR A M TGG+ L KD ++S ELY+EA + A AMKGRLA++YY+ +EE + ME
Sbjct: 79 FNIREAWRHAIQKAKHMPDPWAEFHLEDIETEYATRYRYNAVTGEWVEDEVLIKMASQPFGRGAMRECFRTKKLSNFLHTQNWKGAFNYVAKRYIETVDRDVYFEDVRLQMEAKLWGEEYNRHK-PPKQVDIVQTSIIEMKNRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIIVDIQGVGDLYTDPQIHTESGTDFGDGNLGVRGMALFFHSHACNKICKSMGLTPFDLSPKEKHVLDHCNKQLESAQ--TILRGTEEKCGSSRVRTMSGSRP------PLLFRLSENSGDES--MSDVAFDSLPSSPCSATPHKMDTLQWPVFNEVDNLVHKDHDQLDNQRDSENGGDSGCPSEKRSDLEDMDHRDRGHSNCNRRRESDEDSLGSSARVSVEKWNLYNSSRVHIHRPSCVAVEVQRLNALELEKKIGKSILGKVHLAMVRYHEAGRFCEK---DQEWDQESALFHLAHAADCGELEAIVGLGLMYSQL-PHHILSELTSEDTQENRIKGFDYLLRAAEAGDRPSMILVARAYDTGVNLGSNRIQDWNEALHWYNAALNMTD-YDEGGEYDGTQDEPRYLLLAREAEMLMTGGFHLAKDPQKSGELYTEAAEAAIQAMKGRLANQYYQKAEEAWAMME 722
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Cavefish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:103031207]) HSP 1 Score: 466.463 bits (1199), Expect = 1.814e-153 Identity = 272/660 (41.21%), Postives = 387/660 (58.64%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAG----------------DKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEH-------NLKKKA-------RFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSC-AVSTDSCS-----LRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ + + DP+ F L E+ TE IRY Y++IT W D+ +KM +PF +GAMREC+R KK+S F H ++WK A N+V+KRYME V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M ++E + RP KPLYHLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFFHSH+CN +C+++GL FD+AP+E QL + +++T+ S R S + S + L E + D N + C G ++ ++ N + S DSGY + +LAE ++ A H ++++KA +S +S+ L + + S + +R HIHRPSC AV + + ++G+S+LG++H + HE GRF ++ D P + ++ LYH + AA +EAI+ + +L L P +L ++ E + KG+ +L +AA AG RPS+M +A A D + DW + W + + D DE GEFD D+P Y++ AR A +F+ GG+ L D +R+ +L++EA + A AMKGRLA++YY +EE + ME
Sbjct: 84 WKHAIEKARAMPDPWAEFHLEEVETEPCIRYRYNAITGDWVQDQVFIKMSSQPFGKGAMRECYRTKKLSNFSHSSNWKCASNYVAKRYMETVDRDVYFEDVRLQMEAKLWGEEYNRH-RPPKQVDIMQMCVVEMASRPGKPLYHLEHYIEGQYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHLCNKICKSMGLTPFDVAPAESTQLDCTNKLLQSAKTMLRGCEEQCGSPRVRTTSFTHVSPHLSRLSETSSADENLSDAESVPCSPLSLGVSVDRSPLGWSFMNEMNEGDRNNTDHKASDSGGDSGYPSERRSEGDLAEHHDRARPAYNRHYSESDEDSVRRKAVLNASKLSLTVNSPDSHTLTEEKWSF-FHSSRAHIHRPSCVAVEVERLNNLMLERKIGKSVLGKVHLAMVRYHEAGRFCEK---DAPWDQKSALYHLERAAMCGELEAIVALGQCYLQL-PHHILSELELEDSDENRKKGFRFLLQAAEAGDRPSMMLVARAFDTGINLPSDRTQDWEEAVQWYDCVLNMTD-YDEGGEFDGMQDDPRYLLLAREAELFQMGGFNLTADPQRAGDLFTEAAEAAMEAMKGRLANQYYMKAEEAWSAME 736
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Cavefish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:103031207]) HSP 1 Score: 466.077 bits (1198), Expect = 2.577e-153 Identity = 267/648 (41.20%), Postives = 381/648 (58.80%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAG----------------DKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYM--NRNHIHRPSC-AVSTDSCS-----LRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ + + DP+ F L E+ TE IRY Y++IT W D+ +KM +PF +GAMREC+R KK+S F H ++WK A N+V+KRYME V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M ++E + RP KPLYHLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFFHSH+CN +C+++GL FD+AP+E QL + +++T+ S R S + S + L E + D N + C G ++ ++ N + S DSGY + +LAE ++ A H + S+ + +++ + ++ +R HIHRPSC AV + + ++G+S+LG++H + HE GRF ++ D P + ++ LYH + AA +EAI+ + +L L P +L ++ E + KG+ +L +AA AG RPS+M +A A D + DW + W + + D DE GEFD D+P Y++ AR A +F+ GG+ L D +R+ +L++EA + A AMKGRLA++YY +EE + ME
Sbjct: 105 WKHAIEKARAMPDPWAEFHLEEVETEPCIRYRYNAITGDWVQDQVFIKMSSQPFGKGAMRECYRTKKLSNFSHSSNWKCASNYVAKRYMETVDRDVYFEDVRLQMEAKLWGEEYNRH-RPPKQVDIMQMCVVEMASRPGKPLYHLEHYIEGQYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHLCNKICKSMGLTPFDVAPAESTQLDCTNKLLQSAKTMLRGCEEQCGSPRVRTTSFTHVSPHLSRLSETSSADENLSDAESVPCSPLSLGVSVDRSPLGWSFMNEMNEGDRNNTDHKASDSGGDSGYPSERRSEGDLAEHHDRARPAYNRH---------YSESDEDSVRRLTEEKWSFFHSSRAHIHRPSCVAVEVERLNNLMLERKIGKSVLGKVHLAMVRYHEAGRFCEK---DAPWDQKSALYHLERAAMCGELEAIVALGQCYLQL-PHHILSELELEDSDENRKKGFRFLLQAAEAGDRPSMMLVARAFDTGINLPSDRTQDWEEAVQWYDCVLNMTD-YDEGGEFDGMQDDPRYLLLAREAELFQMGGFNLTADPQRAGDLFTEAAEAAMEAMKGRLANQYYMKAEEAWSAME 737
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Cavefish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:103031207]) HSP 1 Score: 464.537 bits (1194), Expect = 1.958e-152 Identity = 271/661 (41.00%), Postives = 383/661 (57.94%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAG----------------DKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLK---------------KKARFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSC-AVSTDSCS-----LRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ + + DP+ F L E+ TE IRY Y++IT W D+ +KM +PF +GAMREC+R KK+S F H ++WK A N+V+KRYME V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M ++E + RP KPLYHLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFFHSH+CN +C+++GL FD+AP+E QL + +++T+ S R S + S + L E + D N + C G ++ ++ N + S DSGY + +LAE ++ A H + K +S +S+ L + + S + +R HIHRPSC AV + + ++G+S+LG++H + HE GRF ++ D P + ++ LYH + AA +EAI+ + +L L P +L ++ E + KG+ +L +AA AG RPS+M +A A D + DW + W + + D DE GEFD D+P Y++ AR A +F+ GG+ L D +R+ +L++EA + A AMKGRLA++YY +EE + ME
Sbjct: 105 WKHAIEKARAMPDPWAEFHLEEVETEPCIRYRYNAITGDWVQDQVFIKMSSQPFGKGAMRECYRTKKLSNFSHSSNWKCASNYVAKRYMETVDRDVYFEDVRLQMEAKLWGEEYNRH-RPPKQVDIMQMCVVEMASRPGKPLYHLEHYIEGQYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHLCNKICKSMGLTPFDVAPAESTQLDCTNKLLQSAKTMLRGCEEQCGSPRVRTTSFTHVSPHLSRLSETSSADENLSDAESVPCSPLSLGVSVDRSPLGWSFMNEMNEGDRNNTDHKASDSGGDSGYPSERRSEGDLAEHHDRARPAYNRHYSESDEDSVRRQKAVLNASKLSLTVNSPDSHTLTEEKWSF-FHSSRAHIHRPSCVAVEVERLNNLMLERKIGKSVLGKVHLAMVRYHEAGRFCEK---DAPWDQKSALYHLERAAMCGELEAIVALGQCYLQL-PHHILSELELEDSDENRKKGFRFLLQAAEAGDRPSMMLVARAFDTGINLPSDRTQDWEEAVQWYDCVLNMTD-YDEGGEFDGMQDDPRYLLLAREAELFQMGGFNLTADPQRAGDLFTEAAEAAMEAMKGRLANQYYMKAEEAWSAME 758
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Cavefish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:103031207]) HSP 1 Score: 462.225 bits (1188), Expect = 4.256e-152 Identity = 267/646 (41.33%), Postives = 374/646 (57.89%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAG----------------DKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSC-AVSTDSCS-----LRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ + + DP+ F L E+ TE IRY Y++IT W D+ +KM +PF +GAMREC+R KK+S F H ++WK A N+V+KRYME V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M ++E + RP KPLYHLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFFHSH+CN +C+++GL FD+AP+E QL + +++T+ S R S + S + L E + D N + C G ++ ++ N + S DSGY + +LAE H+ + ++ F S +R HIHRPSC AV + + ++G+S+LG++H + HE GRF ++ D P + ++ LYH + AA +EAI+ + +L L P +L ++ E + KG+ +L +AA AG RPS+M +A A D + DW + W + + D DE GEFD D+P Y++ AR A +F+ GG+ L D +R+ +L++EA + A AMKGRLA++YY +EE + ME
Sbjct: 105 WKHAIEKARAMPDPWAEFHLEEVETEPCIRYRYNAITGDWVQDQVFIKMSSQPFGKGAMRECYRTKKLSNFSHSSNWKCASNYVAKRYMETVDRDVYFEDVRLQMEAKLWGEEYNRH-RPPKQVDIMQMCVVEMASRPGKPLYHLEHYIEGQYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHLCNKICKSMGLTPFDVAPAESTQLDCTNKLLQSAKTMLRGCEEQCGSPRVRTTSFTHVSPHLSRLSETSSADENLSDAESVPCSPLSLGVSVDRSPLGWSFMNEMNEGDRNNTDHKASDSGGDSGYPSERRSEGDLAE----------HHDRLTEEKWSFFHS----------------SRAHIHRPSCVAVEVERLNNLMLERKIGKSVLGKVHLAMVRYHEAGRFCEK---DAPWDQKSALYHLERAAMCGELEAIVALGQCYLQL-PHHILSELELEDSDENRKKGFRFLLQAAEAGDRPSMMLVARAFDTGINLPSDRTQDWEEAVQWYDCVLNMTD-YDEGGEFDGMQDDPRYLLLAREAELFQMGGFNLTADPQRAGDLFTEAAEAAMEAMKGRLANQYYMKAEEAWSAME 718
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Cavefish
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:103031207]) HSP 1 Score: 431.795 bits (1109), Expect = 5.425e-141 Identity = 262/630 (41.59%), Postives = 364/630 (57.78%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSC-AVSTDSCS-----LRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
W+ + + DP+ F L E+ TE IRY + I ++ PF +GAMREC+R KK+S F H ++WK A N+V+KRYME V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M ++E + RP KPLYHLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFFHSH+CN +C+++GL FD+AP+E QL + +++T+ S R S + S + L E + D N + C G ++ S DSGY + S+ EH+ + F F L K + S + +R HIHRPSC AV + + ++G+S+LG++H + HE GRF ++ D P + ++ LYH + AA +EAI+ + +L L P +L ++ E + KG+ +L +AA AG RPS+M +A A D + DW + W + + D DE GEFD D+P Y++ AR A +F+ GG+ L D +R+ +L++EA + A AMKGRLA++YY +EE + ME
Sbjct: 84 WKHAIEKARAMPDPWAEFHLEEVETEPCIRY------------RNIFLLQ--PFGKGAMRECYRTKKLSNFSHSSNWKCASNYVAKRYMETVDRDVYFEDVRLQMEAKLWGEEYNRH-RPPKQVDIMQMCVVEMASRPGKPLYHLEHYIEGQYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHLCNKICKSMGLTPFDVAPAESTQLDCTNKLLQSAKTMLRGCEEQCGSPRVRTTSFTHVSPHLSRLSETSSADENLSDAESVPCSPLSLGVSVDRSP-----LDSGGDSGYPSER-----------RSEGDLAEHHDRV---FIFLFFLLTVLVKEKWSF-FHSSRAHIHRPSCVAVEVERLNNLMLERKIGKSVLGKVHLAMVRYHEAGRFCEK---DAPWDQKSALYHLERAAMCGELEAIVALGQCYLQL-PHHILSELELEDSDENRKKGFRFLLQAAEAGDRPSMMLVARAFDTGINLPSDRTQDWEEAVQWYDCVLNMTD-YDEGGEFDGMQDDPRYLLLAREAELFQMGGFNLTADPQRAGDLFTEAAEAAMEAMKGRLANQYYMKAEEAWSAME 673
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Nematostella
Match: EDO36975 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SH28]) HSP 1 Score: 324.324 bits (830), Expect = 7.641e-101 Identity = 226/637 (35.48%), Postives = 340/637 (53.38%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSE-LPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHG-NDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV--DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQ------IHTSCRNGYGNGNLGPRGMAL--FFHSHICNN-VCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQ--STPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIEC-----LTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICL-NLA--EDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSCAVSTDSCSLRMGESILGEIHHEISNMHEIGRF-ADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQ--LDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYY 2126
W+ ++ ++DP+ F + + E +R+ Y++I KSW D+ +KME PF++GAMR C+RLKK+S F N+WK A N+V+K Y+E V R+ YFEDV LQMDAKLW EE+NR+ KK VDI + IIE +R PLYHLEHFIEG Y KYNSNSGFV D+ R TPQAFSHFTFERSGH+LIVVDIQ + ++ + P+ + S + PR + L + +C++ +C+ LGL FD++ E K++ S+ I V Q ST ++S + S SA+ D+ E L + S E ++ C G+ + S S + D D+ L N++ +D QN H K + F + S L + + + R + S+LG++H E++ EIGRF +DR EP + E+ ++H + AA A++ +A +L L P DL+++ T+Q E KG + +AA G R +++ +A A D W + W + ++ ID+ L EN + D+P + + +R A ++ TGG L++D + + +L+S AGDEA AAMKG+LA+KYY
Sbjct: 21 WKDAVKKAWSMTDPWAKFHIHDNCAMEIAVRHRYNAIKKSWVKDEIRIKMESVPFDQGAMRVCYRLKKLSNFSKHNNWKHASNYVAKSYIEEVSRDQYFEDVRLQMDAKLWGEEYNRRDPPKK-VDIFQTYIIELKERTGSPLYHLEHFIEGTYKKYNSNSGFVLRDETLRCTPQAFSHFTFERSGHQLIVVDIQAI-NMNSSPKQPRHLRVSISLAINMNSSPKQPRHLRLLPLTKTRLCHSRICKTLGLTEFDISAVEDKRIDSA---------IQVIQDSSTVVKSSLEDQLSPRKMSAIFDLSEYCLGQ-SPPPSPGATEVSPRSSVSSCNGNPS---------MSDSETSETESDTDVFLSNISSEDDDDVKQNYLSVHVHKASSVF----AESEQLAQAREQQKEKLLR-----------------QKSVSVLGKVHLEMAKYGEIGRFTSDR----EP-DMESAMFHMEKAAQCGITTALVTLAEIYLQL-PHDLMESATVQETEENTNKGVELMLQAAERGDRQAMLYMAKAYDTGYGLGTNMKRSWKEAVKWYQNAIDVIDEDDLPEN----TLLDDPVHTLLSRQAELYFTGGPELERDPQCAGDLFSSAGDEAMAAMKGKLANKYY 605
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Nematostella
Match: EDO35977 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJY5]) HSP 1 Score: 82.0333 bits (201), Expect = 1.809e-16 Identity = 38/71 (53.52%), Postives = 50/71 (70.42%), Query Frame = 3
Query: 804 QAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNG-YGNGNLGPRGMALFFHSHICNNVCEALGLAR 1013
+AFSHFT+ +G + +V DIQGV + YTDPQIHT+ YG GN GP G+ +F H CN++C+ALGL R
Sbjct: 314 EAFSHFTYHITGGQELVCDIQGVNNDYTDPQIHTNPLTSRYGKGNFGPMGIHIFLKDHHCNSMCKALGLPR 384
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Nematostella
Match: EDO40068 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S899]) HSP 1 Score: 75.485 bits (184), Expect = 2.277e-15 Identity = 50/182 (27.47%), Postives = 91/182 (50.00%), Query Frame = 3
Query: 537 FVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQ------PGVKKEVDIVRMSIIEFSDRPDK--PLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQ-------AFSHFTFERSGHELIVVDIQGVG------DLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSH--ICNNVCEALGLAR 1013
+V+K+Y E + Y +DV QM A+ + +FN++ + +++++ + ++ + ++E ++ G + K +N FV P AFSHFT++ S +L++VDIQG TDPQIH++ + +G GN +G+ F+ + CN +C+ LGL R
Sbjct: 42 YVAKQYYEEQPIKQYQQDVLSQMTARSYVAQFNQKLFMLDRGKASNLFTFLPVALLQLFNNANEVEQVCNIEPYMSGEFTKLTNNLTFVRKDEDGNPVKGADLVLAFSHFTWQSSNGKLVIVDIQGWTPKGRGCTFLTDPQIHSAVYDCFGTGNWKQQGIDKFWSAMHPECNAICKLLGLVR 223
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Nematostella
Match: EDO27286 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T9N8]) HSP 1 Score: 65.855 bits (159), Expect = 4.025e-13 Identity = 38/113 (33.63%), Postives = 59/113 (52.21%), Query Frame = 3
Query: 720 HLEHFIEGNYIKYNSNSGFVDDRNRNTP-------QAFSHFTFERSGHELIVVDIQGVG------DLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSH--ICNNVCEALGLAR 1013
++E ++ G + K +N FV P AFSHFT++ S +L++VDIQG TDPQIH++ + +G GN +G+ F+ + CN +C+ LGL R
Sbjct: 1 NIEPYMSGEFTKLTNNLTFVRKDEDGNPVKGADLVLAFSHFTWQSSNGKLVIVDIQGWTPKGRGCTFLTDPQIHSAVYDCFGTGNWKQQGIDKFWSAMHPECNAICKLLGLVR 113
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Medaka
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:101158311]) HSP 1 Score: 452.21 bits (1162), Expect = 1.929e-148 Identity = 265/628 (42.20%), Postives = 368/628 (58.60%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFV-DDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIEC------LTQCAGDKNEQ---KNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSCAVSTDSCSL------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYY 2126
W++ + + DP+ F L E+PTE +RY Y++IT W D+ +KM +PF +GAMRECFR KK+S F H ++WK A N+V+KRYM+ V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M ++E ++RP KPL+HLEH+IEG YIKYNSNSGFV DD R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFFHSH+CN +C+++GL FDL+P E+ QL + +++T+ S R S S L L E + D + I C T + Q F Q S DSGY + D S + + +K F F SS R+H+HRPSC V+T+ L ++G+S LG++H + HE GRF ++ DE + + ++H + AA +EAI+ + +L L P +L ++ + + KG+ YL +AA AG R S++ +A A D + DW+ +HW + + D DE GEFD T D P Y++ AR A M++ GG+ L D +R+ +L++EA + A AAMKGRLA++YY
Sbjct: 87 WKNAIEKARAMPDPWAQFHLEEIPTESCMRYRYNAITGEWHQDQIHIKMGSQPFGKGAMRECFRSKKLSNFSHSSNWKSASNYVAKRYMQEVDRDVYFEDVRLQMEAKLWGEEYNRHR-PPKQVDIMQMCVVEMTNRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHMCNKICKSMGLTPFDLSPEEMSQLDGTNKLLKSAQTVLRGCEEQCGSPRVRTWSASRAPPLFSRLSETSSADESMSDAESIPCSPLNPPFTAVGSLGDSQLLFHFLFCQESESGGDSGYPSER----RSEPDSSDHMDGVNIYLTDEKWSF-FHSS-----------------RSHVHRPSC-VATEVERLNTLLQKKIGQSNLGKVHLAMVRYHEAGRFCEK---DEQWDESSAMFHLERAALCGELEAIVALGQCYLRL-PHHILPDMELEDNAGNRMKGFKYLLQAAEAGDRSSMIIVARAFDSGINLSADRKQDWAEAIHWYDSALNMSD-FDEGGEFDGTQDEPRYLLLAREAEMYQKGGHNLAADPQRAGDLFTEAAEAAMAAMKGRLANQYY 685
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Medaka
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:101158311]) HSP 1 Score: 343.584 bits (880), Expect = 2.124e-106 Identity = 166/312 (53.21%), Postives = 215/312 (68.91%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRN-RNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIEC 1223
W++ + + DP+ F L E+PTE +RY Y++IT W D+ +KM +PF +GAMRECFR KK+S F H ++WK A N+V+KRYM+ V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M ++E ++RP KPL+HLEH+IEG YIKYNSNSGFV D N R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFFHSH+CN +C+++GL FDL+P E+ QL + +++T+ S R S S L L E + D + I C
Sbjct: 86 WKNAIEKARAMPDPWAQFHLEEIPTESCMRYRYNAITGEWHQDQIHIKMGSQPFGKGAMRECFRSKKLSNFSHSSNWKSASNYVAKRYMQEVDRDVYFEDVRLQMEAKLWGEEYNRH-RPPKQVDIMQMCVVEMTNRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHMCNKICKSMGLTPFDLSPEEMSQLDGTNKLLKSAQTVLRGCEEQCGSPRVRTWSASRAPPLFSRLSETSSADESMSDAESIPC 396 HSP 2 Score: 132.88 bits (333), Expect = 1.367e-31 Identity = 83/227 (36.56%), Postives = 133/227 (58.59%), Query Frame = 3
Query: 1464 NRNHIHRPSCAVSTDSCSL------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYY 2126
+R+H+HRPSC V+T+ L ++G+S LG++H + HE GRF ++ DE + + ++H + AA +EAI+ + +L LP +L ++ + + KG+ YL +AA AG R S++ +A A D + DW+ +HW + + D DE GEFD T D P Y++ AR A M++ GG+ L D +R+ +L++EA + A AAMKGRLA++YY
Sbjct: 510 SRSHVHRPSC-VATEVERLNTLLQKKIGQSNLGKVHLAMVRYHEAGRFCEK---DEQWDESSAMFHLERAALCGELEAIVALGQCYLRLP-HHILPDMELEDNAGNRMKGFKYLLQAAEAGDRSSMIIVARAFDSGINLSADRKQDWAEAIHWYDSALNMSD-FDEGGEFDGTQDEPRYLLLAREAEMYQKGGHNLAADPQRAGDLFTEAAEAAMAAMKGRLANQYY 730
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Medaka
Match: eef2k (eukaryotic elongation factor 2 kinase [Source:NCBI gene;Acc:101158311]) HSP 1 Score: 343.969 bits (881), Expect = 2.674e-106 Identity = 156/266 (58.65%), Postives = 203/266 (76.32%), Query Frame = 3
Query: 294 WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTF-HGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRN-RNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETI 1085
W++ + + DP+ F L E+PTE +RY Y++IT W D+ +KM +PF +GAMRECFR KK+S F H ++WK A N+V+KRYM+ V+R+VYFEDV LQM+AKLW EE+NR K+VDI++M ++E ++RP KPL+HLEH+IEG YIKYNSNSGFV D N R TPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT +G+GNLG RGMALFFHSH+CN +C+++GL FDL+P E+ QL + +++T+
Sbjct: 102 WKNAIEKARAMPDPWAQFHLEEIPTESCMRYRYNAITGEWHQDQIHIKMGSQPFGKGAMRECFRSKKLSNFSHSSNWKSASNYVAKRYMQEVDRDVYFEDVRLQMEAKLWGEEYNRH-RPPKQVDIMQMCVVEMTNRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFHSHMCNKICKSMGLTPFDLSPEEMSQLDGTNKLLKSAQTV 366 HSP 2 Score: 132.494 bits (332), Expect = 1.663e-31 Identity = 83/227 (36.56%), Postives = 133/227 (58.59%), Query Frame = 3
Query: 1464 NRNHIHRPSCAVSTDSCSL------RMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYY 2126
+R+H+HRPSC V+T+ L ++G+S LG++H + HE GRF ++ DE + + ++H + AA +EAI+ + +L LP +L ++ + + KG+ YL +AA AG R S++ +A A D + DW+ +HW + + D DE GEFD T D P Y++ AR A M++ GG+ L D +R+ +L++EA + A AAMKGRLA++YY
Sbjct: 526 SRSHVHRPSC-VATEVERLNTLLQKKIGQSNLGKVHLAMVRYHEAGRFCEK---DEQWDESSAMFHLERAALCGELEAIVALGQCYLRLP-HHILPDMELEDNAGNRMKGFKYLLQAAEAGDRSSMIIVARAFDSGINLSADRKQDWAEAIHWYDSALNMSD-FDEGGEFDGTQDEPRYLLLAREAEMYQKGGHNLAADPQRAGDLFTEAAEAAMAAMKGRLANQYY 746
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Medaka
Match: ENSORLT00000015478.2 (pep primary_assembly:ASM223467v1:18:28495114:28504476:1 gene:ENSORLG00000012361.2 transcript:ENSORLT00000015478.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 80.1073 bits (196), Expect = 4.221e-15 Identity = 70/250 (28.00%), Postives = 117/250 (46.80%), Query Frame = 3
Query: 339 RTFKLSELPTEKVIRYL-YDSITKSWKTDKAIV------KMEKEPFNRGAMRECFRLKKISTFHGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVD----IVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQ--AFSHFTFERSGHELIVVDIQGV------GDLY-TDPQIHTSCRNGYGNGNLGPRGMALFF---HSHICNNVCEALGLARFD 1019
RTF+L +L +L + W + V +M +P +G+ RE ++ + + +R ++V K Y++ +++ DV QM A+ + EFN++ K ++ I +++ + + +E FI GN++K +N+G ++R T AF HFT+ S + +VVD+QG G Y TDPQIH S R G + RG+ LF H CN +C+ L L D
Sbjct: 499 RTFRLHQLSAAHGALHLKFSKEAGLWTARETCVYIGTPIEMNGKPL-QGSQREAIWVQFL-----HQEERLSSYVGKNYLKPSGIQLHLNDVERQMTAQYYVTEFNKKLYDKNDMAQIFYIPSEALLILNGKEIVGCITVEPFILGNFVKLTNNTGKKEERLSATKYGIAFGHFTYLLSNCQEVVVDLQGWVTANGKGLTYLTDPQIH-STRTRRGTSDFAERGIRLFLKDQHGPKCNEICQLLKLPPLD 741
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Medaka
Match: trpm7 (transient receptor potential cation channel subfamily M member 7 [Source:NCBI gene;Acc:101156483]) HSP 1 Score: 69.3218 bits (168), Expect = 1.330e-11 Identity = 68/241 (28.22%), Postives = 105/241 (43.57%), Query Frame = 3
Query: 408 SWKTDKAIVKME---KEPFNRGAMRECFRLKKISTFHGNDWKRAGN-FVSKRYMENV---EREVYFEDVCLQMDAKLWAEEFNRQPGVKK---EVDIVRMSIIEFSDR----------PDKPLYHLEHFIEGNYIKYNSNSG---FVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNG-----YGNGNLGPRGMALFFHSHICNNVCEALGLA---RFDLAPSEL 1037
SW K+E KE G R LK + T+ D + G+ ++ K ++ V + +Y ED L L E +Q +K + +R I +S R + +E I G + K+N+N+G + T AFSH+T+E + EL+V+D+QGVG++ TDP + S G +G NLG + F H CN+ C L L R D P ++
Sbjct: 1665 SWSQRGFCAKIEFLSKEEMGGGLRRA---LKVLCTWSEYDILKPGHLYIVKSFLPEVIQTWQSIYKEDTVLH----LCLREIQQQRAAQKLTFAFNQIRPKTIPYSPRFLEVFLLYCHSAGQWFAIEECITGEFRKFNNNNGDEIVPTNLLEETMLAFSHWTYEYTRGELLVLDLQGVGEILTDPSVIKSGEKGSYDMIFGPANLGDDAIRNFRAKHHCNSCCRKLKLPDLKRNDYTPDKV 1898
BLAST of Eukaryotic elongation factor 2 kinase vs. Planmine SMEST
Match: SMESG000014704.1 (SMESG000014704.1) HSP 1 Score: 1452.96 bits (3760), Expect = 0.000e+0 Identity = 694/694 (100.00%), Postives = 694/694 (100.00%), Query Frame = 3
Query: 78 MINEELAEDEDSIDSELLRNVVKCEENVPKRRRMSVNVFKLKKSQHSIDVDHLKSESMSNDDSIKHLKVPKLWQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSCAVSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
MINEELAEDEDSIDSELLRNVVKCEENVPKRRRMSVNVFKLKKSQHSIDVDHLKSESMSNDDSIKHLKVPKLWQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSCAVSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME
Sbjct: 1 MINEELAEDEDSIDSELLRNVVKCEENVPKRRRMSVNVFKLKKSQHSIDVDHLKSESMSNDDSIKHLKVPKLWQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGNDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAYMNRNHIHRPSCAVSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 694
BLAST of Eukaryotic elongation factor 2 kinase vs. Planmine SMEST
Match: SMESG000020757.1 (SMESG000020757.1) HSP 1 Score: 506.908 bits (1304), Expect = 4.284e-170 Identity = 280/671 (41.73%), Postives = 411/671 (61.25%), Query Frame = 3
Query: 168 RRRMSVNVFKLKKSQHSIDVDHLKSESMSNDDSIKHLKVPKL--WQSLARRTLMLSDPFRTFKLSELPTEKVIRYLYDSITKSW-KTDKAIVKMEKEPFNRGAMRECFRLKKISTFHG--NDWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAY-MNRNHIHRPSCAVSTDSCSLRMG--ESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEM 2156
R+ ++V K+ K++ ++ ++ + S+ +++ + + W+S + L DP++ F L ++ +EKV RY+++S T W ++ + VKME +PFNRGAMRECFRLKK+S+ DW RAGN+V+KRY+E V+ VY+EDV LQMDAKLW +E++RQPGV K+VDI +MS+I+F DRP +PLYHLEHFIEG+YIKYNSNSGFVD+ +RNTPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT + YG+GNLGPRGMALFFHSH+CN +C LGL +FDL+ SE + + ++ TIA+ S ++S+ + + L+ L DN+ E +N + SS ++ + + + AED + C + K F + S++ +DS + Y +N++ HR SC V+ + L+M E ILGEIHHE++ +H G+F N++ + INWE VL+HE+LAA L +E++ N++ ++L + L + C + K KG Y+ AA G R S++ L D + ++ + H +W W E + + + D +G FDS D P + +KARMA + GG GLDKD + LYS+A D AT A GR A+KY+ ++EE+ ++
Sbjct: 41 RKNLTVRHHKISKAERNLMTNYRINFSIKEPNNLPSHRYKSIDRWKSALIKFKKLKDPWKNFDLDKIISEKVERYIFNSFTGLWLQSVEYKVKMESKPFNRGAMRECFRLKKMSSLFKEEKDWYRAGNYVAKRYIEPVDGSVYYEDVKLQMDAKLWGQEYSRQPGVIKKVDICQMSVIKFVDRPGQPLYHLEHFIEGDYIKYNSNSGFVDENSRNTPQAFSHFTFERSGHKLIVVDIQGVGDLYTDPQIHTFAKIDYGDGNLGPRGMALFFHSHVCNAICSILGLQKFDLSKSESEDINQRHLRGNSNGTIAIRNSEKVKSIYEENDTYDADQILMSRL----------NYDNISE--------QNSDE--------SSLENSNSIESNSIIYEAED----GDDECSEAVGKLHNFCRNRLRSSEYATNDDSYNQYFINKSMEHRSSCVVNNLTSPLQMKYKECILGEIHHELARLHSSGKFITDNKI-QNINWEVVLFHEELAAKLGYLESMCNLSRFYLDIDRDSLFENCLFKLTEMDKEKGLQYMIMAAEYGDRRSMIFLGD-HYRKEPQFH----NWYEAYKWYECAITSAEDSDISGGFDSVADVPLFEIKARMAEIKYIGGNGLDKDLNSAYNLYSQAADHATMAGNGRCATKYFTIAEEILSKL 675
BLAST of Eukaryotic elongation factor 2 kinase vs. Planmine SMEST
Match: SMESG000077033.1 (SMESG000077033.1) HSP 1 Score: 441.039 bits (1133), Expect = 1.415e-146 Identity = 240/550 (43.64%), Postives = 339/550 (61.64%), Query Frame = 3
Query: 516 DWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRNRNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSELKQLQSSRGSSITSETIAVHQSTPLRSLRSSKPSNSLESALIDMLEEHLNEDSNEQIDNVIECLTQCAGDKNEQKNKFLQFQVSSPDSGYDYDEDICLNLAEDLSASQNATCEHNLKKKARFKFDSSNSNDLKKGEDSLDAY-MNRNHIHRPSCAVSTDSCSLRMG--ESILGEIHHEISNMHEIGRFADRNQLDEPINWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADANDVEQSKIHGSDPDWSSVMHWLERTVETIDQLDENGEFDSTNDNPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEM 2156
DW RAGN+V+KRY+E V+ VY+EDV LQMDAKLW +E++RQPGV K+VDI +MS+I+F DRP +PLYHLEHFIEG+YIKYNSNSGFVD+ +RNTPQAFSHFTFERSGH+LIVVDIQGVGDLYTDPQIHT + YG+GNLGPRGMALFFHSH+CN +C LGL +FDL+ SE + + ++ TIA+ S ++S+ + + L+ L DN+ E +N + SS ++ + + + AED + C + K F + S++ +DS + Y +N++ HR SC V+ + L+M E ILGEIHHE++ +H G+F N++ + INWEAVL+HE+LAA L +E++ N++ ++L + L + C + K KG Y+ AA G R S++ L D + ++ + H +W W E + + + D +G FDS D P + +KARMA + GG GLD+D + LYS+A D AT A GR A+KY+ ++EE+ ++
Sbjct: 10 DWYRAGNYVAKRYIEPVDGSVYYEDVKLQMDAKLWGQEYSRQPGVIKKVDICQMSVIKFVDRPGQPLYHLEHFIEGDYIKYNSNSGFVDENSRNTPQAFSHFTFERSGHKLIVVDIQGVGDLYTDPQIHTFAKIDYGDGNLGPRGMALFFHSHVCNAICSILGLQKFDLSKSESEDINQRHLRGNSNGTIAIRNSEKVKSIYEENDTYDADQILMSRL----------NYDNISE--------QNSDE--------SSLENSNSIESNSIIYEAED----GDDECSEAVGKLHNFCRNRLRSSEYATNDDSYNQYFINKSMEHRSSCVVNNLTSPLQMKYKECILGEIHHELARLHSSGKFITDNKI-QNINWEAVLFHEELAAKLGYLESMCNLSRFYLDIDRDSLFENCLFKLTEMDKEKGLQYMIMAAEYGDRRSMIFLGD-HYRKEPQFH----NWYEAYKWYECAITSAEDSDISGGFDSVADVPLFEIKARMAEIKYIGGNGLDQDLNSAYNLYSQAADHATMAGNGRCATKYFTIAEEILSKL 523
BLAST of Eukaryotic elongation factor 2 kinase vs. Planmine SMEST
Match: SMESG000034660.1 (SMESG000034660.1) HSP 1 Score: 310.842 bits (795), Expect = 9.283e-94 Identity = 167/328 (50.91%), Postives = 216/328 (65.85%), Query Frame = 3
Query: 81 INEELAEDEDSIDSELLRNVVKCEENVPKRRRMSVNVFKLKKSQ--HSIDVDHLKSESMSNDDSIKHLKVPKLWQSLARRTLMLSD---PFRTFKLSELPTEKVIRYLYDSITKSWKTDKAIVKMEKEPFNRGAMRECFRLKKISTFHGN---DWKRAGNFVSKRYMENVEREVYFEDVCLQMDAKLWAEEFNRQPGVKKEVDIVRMSIIEFSDRPDKPLYHLEHFIEGNYIKYNSNSGFVDDRN-RNTPQAFSHFTFERSGHELIVVDIQGVGDLYTDPQIHTSCRNGYGNGNLGPRGMALFFHSHICNNVCEALGLARFDLAPSEL 1037
++E++ ED+ SELL N ++C + SVN K + + HS+ + +S D LK W + D P+ F + + +K IRY Y +I K W D+ VK+E PF+ GAMRECFRLKK+ST N DW + N+V+K+Y+ V R+VYFEDV LQM++KLWAEE+NRQ KK +DI ++SIIE DR +KPLYH+EHF+EG Y+KYNSNSG+VDD RNTPQAFSHFTFERSGH +I+VDIQGVGDLYTDPQ+HT+ YG+GNLG RGMALFF SH CN +C LGL+ FD+ +EL
Sbjct: 1 MDEDIESCEDTNFSELL-NSLECNTELDDLALYSVNSIKYRNQRRPHSLSISWNSPDSDRTDTISPALK---RWFRAVSKICKHDDDIDPWHDFTIDTIKPDKAIRYRYSAIKKKWVQDEIWVKLETLPFDHGAMRECFRLKKLSTTGINNNHDWNFSSNYVAKQYINLVNRDVYFEDVKLQMESKLWAEEYNRQNPPKK-IDIFQLSIIELIDRENKPLYHIEHFMEGTYLKYNSNSGYVDDSCLRNTPQAFSHFTFERSGHRIIIVDIQGVGDLYTDPQVHTADGLNYGDGNLGLRGMALFFSSHRCNPICHFLGLSEFDMHQNEL 323 HSP 2 Score: 140.969 bits (354), Expect = 2.609e-34 Identity = 90/290 (31.03%), Postives = 144/290 (49.66%), Query Frame = 3
Query: 1440 EDSLDAYMNRNHIHRPSCAVSTDSCSLRMGESILGEIHHEISNMHEIGRFADRNQL-----------------DEP--------------INWEAVLYHEDLAASLNCMEAILNMANYHLGLPPRDLLKACTIQPDPEKKFKGWIYLTKAANAGHRPSIMALADA-----------NDVEQSKIHGSDPDWSSVMHWLERTVETIDQLD-------ENGEFDSTND-NPSYVVKARMAAMFRTGGYGLDKDTERSAELYSEAGDEATAAMKGRLASKYYELSEEVYGEME 2159
E+ L Y + +PS A + +G SIL ++HHE++ +HE GRF +L D P INWE+ L+HE AA L C+EA++ MA Y L + +L+ C + P+ G YL +AA++G R S++ LA+ N++ ++ + + +W + W +R E +++LD G +DS D P + A MA ++ GGYGL+K+ + + ELYS+A + AT A++GR A KYYEL++ Y + E
Sbjct: 495 EEHLAVYHSMKENQKPSSATHPTNLDQEIGHSILAQVHHELARLHESGRFVKSKRLAPGCLHHQFWSNLLNENDSPEESEQKSPTNHDLDINWESCLFHERHAAQLGCLEAVIVMARYCLNMSGH-MLQDCPLPPNQNDIECGLDYLWRAADSGDRRSMIELANLYRKTEYFGEIFNEINKTTL---EVNWFEAVKWYKRAFEAVNKLDGQIDSKDAEGRYDSAEDLMPPQEILASMAELYLKGGYGLEKNCQLAGELYSQAAEIATNALQGRQAVKYYELADTAYSQDE 780 The following BLAST results are available for this feature:
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Eukaryotic elongation factor 2 kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Eukaryotic elongation factor 2 kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Eukaryotic elongation factor 2 kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Eukaryotic elongation factor 2 kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 4
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30022256 ID=SMED30022256|Name=Eukaryotic elongation factor 2 kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=2377bpback to top protein sequence of SMED30022256-orf-1 >SMED30022256-orf-1 ID=SMED30022256-orf-1|Name=SMED30022256-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=695bp MINEELAEDEDSIDSELLRNVVKCEENVPKRRRMSVNVFKLKKSQHSIDVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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