Coiled-coil domain-containing protein 77

Overview
NameCoiled-coil domain-containing protein 77
Smed IDSMED30022246
Length (bp)1630
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Coiled-coil domain-containing protein 77 (SMED30022246) t-SNE clustered cells

Violin plots show distribution of expression levels for Coiled-coil domain-containing protein 77 (SMED30022246) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Coiled-coil domain-containing protein 77 (SMED30022246) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Coiled-coil domain-containing protein 77 (SMED30022246) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30022246

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30022246SMESG000045184.1 dd_Smed_v4_4812_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30022246SMESG000045184.1 dd_Smed_v4_4812_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30022246SMESG000045184.1 dd_Smed_v4_4812_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30022246SMESG000045184.1 dd_Smed_v4_4812_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022246SMESG000045184.1 Contig15932newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022246SMESG000045184.1 Contig15932uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022246SMESG000045184.1 Contig39787newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30022246SMESG000045184.1 Contig39787uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30022246SMESG000045184.1 dd_Smed_v6_4812_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30022246SMESG000045184.1 SMESG000045185.1 OX_Smed_1.0.13109ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30022246SMESG000045184.1 Contig15932newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30022246SMESG000045184.1 Contig15932uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
epidermisSMED30022246SMESG000045184.1 dd_Smed_v4_4812_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Human
Match: CCDC77 (coiled-coil domain containing 77 [Source:HGNC Symbol;Acc:HGNC:28203])

HSP 1 Score: 332.413 bits (851), Expect = 3.587e-108
Identity = 205/481 (42.62%), Postives = 301/481 (62.58%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVI--QPNQAVTLV---TSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQS-KAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            L  L PS+ELL++Y++K+A+   +++ L++KLE   E  + Q+ +  DL+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP K  I  +  QAV       S  F     I+++  +  R  ++            EH   +R++++  +Q++ALQ+QL EQT+L +EQ + L+EDR I  +E + Q  R+Q KI+ L+  L  TQELLY++TKDFL  RS+ +  EK W+ EKD +  K+K       +    +K   V P   +S  A SE+   +KD               +L Q++KL+ MY+EQ I +E ELA+IREE    ++I+K R+ K+  RLQIM +RY+ LERRR LEV+GF+TDI  LR+KLK+LE+ LY  T++               N DLA+L EV+ +  R++ + G+LK+LK+ ++GLE ELR
Sbjct:   17 LAKLHPSKELLEYYQKKMAECEAENEDLLKKLELYKEACEGQHKLECDLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGTDAGEVTYFCKEPPHKVTILQKTIQAVGECEQSESSAFKADPKISKRRPSRERKESS------------EH--YQRDIQTLILQVEALQAQLGEQTKLSREQIEGLIEDRRIHLEEIQVQHQRNQNKIKELTKNLHHTQELLYESTKDFLQLRSENQNKEKSWMLEKDNLMSKIKQYRVQCKKK--EDKIGKVLPVMHESHHAQSEYIKSLKD---------------KLVQEKKLSNMYQEQCISLEEELARIREEEGMRREIFKDRTNKMGKRLQIMTKRYEALERRRILEVEGFKTDIKVLRQKLKDLEQMLYKATVN------------ARANQDLALLCEVRDSNRRAHKIQGELKNLKSKVFGLENELR 454
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Human
Match: CCDC77 (coiled-coil domain containing 77 [Source:HGNC Symbol;Acc:HGNC:28203])

HSP 1 Score: 332.413 bits (851), Expect = 3.587e-108
Identity = 205/481 (42.62%), Postives = 301/481 (62.58%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVI--QPNQAVTLV---TSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQS-KAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            L  L PS+ELL++Y++K+A+   +++ L++KLE   E  + Q+ +  DL+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP K  I  +  QAV       S  F     I+++  +  R  ++            EH   +R++++  +Q++ALQ+QL EQT+L +EQ + L+EDR I  +E + Q  R+Q KI+ L+  L  TQELLY++TKDFL  RS+ +  EK W+ EKD +  K+K       +    +K   V P   +S  A SE+   +KD               +L Q++KL+ MY+EQ I +E ELA+IREE    ++I+K R+ K+  RLQIM +RY+ LERRR LEV+GF+TDI  LR+KLK+LE+ LY  T++               N DLA+L EV+ +  R++ + G+LK+LK+ ++GLE ELR
Sbjct:   17 LAKLHPSKELLEYYQKKMAECEAENEDLLKKLELYKEACEGQHKLECDLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGTDAGEVTYFCKEPPHKVTILQKTIQAVGECEQSESSAFKADPKISKRRPSRERKESS------------EH--YQRDIQTLILQVEALQAQLGEQTKLSREQIEGLIEDRRIHLEEIQVQHQRNQNKIKELTKNLHHTQELLYESTKDFLQLRSENQNKEKSWMLEKDNLMSKIKQYRVQCKKK--EDKIGKVLPVMHESHHAQSEYIKSLKD---------------KLVQEKKLSNMYQEQCISLEEELARIREEEGMRREIFKDRTNKMGKRLQIMTKRYEALERRRILEVEGFKTDIKVLRQKLKDLEQMLYKATVN------------ARANQDLALLCEVRDSNRRAHKIQGELKNLKSKVFGLENELR 454
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Human
Match: CCDC77 (coiled-coil domain containing 77 [Source:HGNC Symbol;Acc:HGNC:28203])

HSP 1 Score: 332.413 bits (851), Expect = 3.587e-108
Identity = 205/481 (42.62%), Postives = 301/481 (62.58%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVI--QPNQAVTLV---TSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQS-KAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            L  L PS+ELL++Y++K+A+   +++ L++KLE   E  + Q+ +  DL+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP K  I  +  QAV       S  F     I+++  +  R  ++            EH   +R++++  +Q++ALQ+QL EQT+L +EQ + L+EDR I  +E + Q  R+Q KI+ L+  L  TQELLY++TKDFL  RS+ +  EK W+ EKD +  K+K       +    +K   V P   +S  A SE+   +KD               +L Q++KL+ MY+EQ I +E ELA+IREE    ++I+K R+ K+  RLQIM +RY+ LERRR LEV+GF+TDI  LR+KLK+LE+ LY  T++               N DLA+L EV+ +  R++ + G+LK+LK+ ++GLE ELR
Sbjct:   17 LAKLHPSKELLEYYQKKMAECEAENEDLLKKLELYKEACEGQHKLECDLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGTDAGEVTYFCKEPPHKVTILQKTIQAVGECEQSESSAFKADPKISKRRPSRERKESS------------EH--YQRDIQTLILQVEALQAQLGEQTKLSREQIEGLIEDRRIHLEEIQVQHQRNQNKIKELTKNLHHTQELLYESTKDFLQLRSENQNKEKSWMLEKDNLMSKIKQYRVQCKKK--EDKIGKVLPVMHESHHAQSEYIKSLKD---------------KLVQEKKLSNMYQEQCISLEEELARIREEEGMRREIFKDRTNKMGKRLQIMTKRYEALERRRILEVEGFKTDIKVLRQKLKDLEQMLYKATVN------------ARANQDLALLCEVRDSNRRAHKIQGELKNLKSKVFGLENELR 454
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Human
Match: CCDC77 (coiled-coil domain containing 77 [Source:HGNC Symbol;Acc:HGNC:28203])

HSP 1 Score: 333.183 bits (853), Expect = 3.842e-108
Identity = 205/481 (42.62%), Postives = 301/481 (62.58%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVI--QPNQAVTLV---TSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQS-KAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            L  L PS+ELL++Y++K+A+   +++ L++KLE   E  + Q+ +  DL+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP K  I  +  QAV       S  F     I+++  +  R  ++            EH   +R++++  +Q++ALQ+QL EQT+L +EQ + L+EDR I  +E + Q  R+Q KI+ L+  L  TQELLY++TKDFL  RS+ +  EK W+ EKD +  K+K       +    +K   V P   +S  A SE+   +KD               +L Q++KL+ MY+EQ I +E ELA+IREE    ++I+K R+ K+  RLQIM +RY+ LERRR LEV+GF+TDI  LR+KLK+LE+ LY  T++               N DLA+L EV+ +  R++ + G+LK+LK+ ++GLE ELR
Sbjct:   49 LAKLHPSKELLEYYQKKMAECEAENEDLLKKLELYKEACEGQHKLECDLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGTDAGEVTYFCKEPPHKVTILQKTIQAVGECEQSESSAFKADPKISKRRPSRERKESS------------EH--YQRDIQTLILQVEALQAQLGEQTKLSREQIEGLIEDRRIHLEEIQVQHQRNQNKIKELTKNLHHTQELLYESTKDFLQLRSENQNKEKSWMLEKDNLMSKIKQYRVQCKKK--EDKIGKVLPVMHESHHAQSEYIKSLKD---------------KLVQEKKLSNMYQEQCISLEEELARIREEEGMRREIFKDRTNKMGKRLQIMTKRYEALERRRILEVEGFKTDIKVLRQKLKDLEQMLYKATVN------------ARANQDLALLCEVRDSNRRAHKIQGELKNLKSKVFGLENELR 486
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Human
Match: CCDC77 (coiled-coil domain containing 77 [Source:HGNC Symbol;Acc:HGNC:28203])

HSP 1 Score: 276.559 bits (706), Expect = 1.748e-87
Identity = 171/401 (42.64%), Postives = 250/401 (62.34%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVI--QPNQAVTLV---TSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQS-KAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQ 1334
            L  L PS+ELL++Y++K+A+   +++ L++KLE   E  + Q+ +  DL+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP K  I  +  QAV       S  F     I+++  +  R  ++            EH   +R++++  +Q++ALQ+QL EQT+L +EQ + L+EDR I  +E + Q  R+Q KI+ L+  L  TQELLY++TKDFL  RS+ +  EK W+ EKD +  K+K       +    +K   V P   +S  A SE+   +KD               +L Q++KL+ MY+EQ I +E ELA+IREE    ++I+K R+ K+  RLQIM +RY+ LERRR LEV+
Sbjct:   17 LAKLHPSKELLEYYQKKMAECEAENEDLLKKLELYKEACEGQHKLECDLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGTDAGEVTYFCKEPPHKVTILQKTIQAVGECEQSESSAFKADPKISKRRPSRERKESS------------EH--YQRDIQTLILQVEALQAQLGEQTKLSREQIEGLIEDRRIHLEEIQVQHQRNQNKIKELTKNLHHTQELLYESTKDFLQLRSENQNKEKSWMLEKDNLMSKIKQYRVQCKKK--EDKIGKVLPVMHESHHAQSEYIKSLKD---------------KLVQEKKLSNMYQEQCISLEEELARIREEEGMRREIFKDRTNKMGKRLQIMTKRYEALERRRILEVE 386
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Zebrafish
Match: ccdc77 (coiled-coil domain containing 77 [Source:ZFIN;Acc:ZDB-GENE-050913-54])

HSP 1 Score: 346.665 bits (888), Expect = 7.430e-114
Identity = 208/479 (43.42%), Postives = 299/479 (62.42%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAV-----IQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLEREL 1571
            L  L+PSRELLDFYR+KV+    +H+ L++KLE+   +++ Q+ + W+++QRE+EI++LQ ALSDMQ+YLF+EREQ LRLYAEND+LKIREL+DRKKIQHLL L G    E+TYF ++PP K       IQP     L        S              N  ++   E+ +  E Q  KR+ ++  +Q++ALQ+Q+EEQ RL KEQ +ALME+R I  +E + Q+ RD ++I AL+DKL+RTQ LL ++T+DFL  + + R  EK W+ EK+ + R+L   E    ++ +    I       QS A S  T          ++  I  L  +L+Q  KLA+MYR+Q + +E EL+QIREEGD  ++I+K RS K+  RLQ+M +RY+ LE+RR +EV+GF+TDI  LR+K+K++EK L+ +T+          P       DLAILREV+ T  R+  +  QLK+LK  +  LE EL
Sbjct:   25 LAYLRPSRELLDFYRQKVSQFDGEHEELLQKLEEHRSSTEEQHKLQWEIRQREEEIAELQNALSDMQIYLFQEREQALRLYAENDRLKIRELEDRKKIQHLLALVGPDPGEITYFHREPPHKVTVPQKKIQPRSHEELKMVKPRPVSA-----------KGNKKSSKHGENSTDAEQQ--KRDNQTLLLQVEALQAQMEEQARLAKEQVEALMEERRIHLEERQIQQQRDSDRITALTDKLQRTQSLLMESTRDFLQLKFESRAQEKSWMMEKERLLRRLDCSEEREERAPSAELQI-----IQQSPADSGAT----------HRQHIRALQEELKQAHKLADMYRDQCVSLETELSQIREEGDVGREIFKERSDKMAKRLQLMTRRYEALEKRRVMEVEGFKTDIRLLRQKVKDVEKILFKLTL-------GGSP-----KQDLAILREVRQTNRRTEKVQDQLKNLKTKICKLENEL 463
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Zebrafish
Match: ccdc77 (coiled-coil domain containing 77 [Source:ZFIN;Acc:ZDB-GENE-050913-54])

HSP 1 Score: 194.512 bits (493), Expect = 4.669e-58
Identity = 109/238 (45.80%), Postives = 156/238 (65.55%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAV-----IQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALS 848
            L  L+PSRELLDFYR+KV+    +H+ L++KLE+   +++ Q+ + W+++QRE+EI++LQ ALSDMQ+YLF+EREQ LRLYAEND+LKIREL+DRKKIQHLL L G    E+TYF ++PP K       IQP     L        S    +K+     N+ +    K+++ +LL             +Q++ALQ+Q+EEQ RL KEQ +ALME+R I  +E + Q+ RD ++I AL+
Sbjct:   25 LAYLRPSRELLDFYRQKVSQFDGEHEELLQKLEEHRSSTEEQHKLQWEIRQREEEIAELQNALSDMQIYLFQEREQALRLYAENDRLKIRELEDRKKIQHLLALVGPDPGEITYFHREPPHKVTVPQKKIQPRSHEELKMVKPRPVSAKGNKKSSKHGENSTDAEQQKRDNQTLL-------------LQVEALQAQMEEQARLAKEQVEALMEERRIHLEERQIQQQRDSDRITALT 249
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Xenopus
Match: pipox (pipecolic acid oxidase [Source:Xenbase;Acc:XB-GENE-1013122])

HSP 1 Score: 376.326 bits (965), Expect = 7.914e-125
Identity = 217/503 (43.14%), Postives = 324/503 (64.41%), Query Frame = 3 
Query:  108 NNSSNKNDSL----YDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGF------TTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKL-KTKESSAGQSGTGNKWIH---VDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            +   N+ DS      +  L  L+PSRELL++YR+K+A+   +H+ L+++LEQ   T + Q+ + W+++QRE+EIS+LQKALSDMQVYLF+ERE VLRLY+END+LKIREL+DRKKIQ LL L G ++ +VTYF K+PP+K  I P +AV   + D +      +   G  +  + A    + +   K+E   +L             +Q++ALQ+QLEEQTRL KEQ + L+EDR +R +ET+ Q  RDQ+K+++++DKL +TQ+LLY++T+DFL  + + R NEK W++EKD + R+L + +E  A  S    +  H   +   SL  KA               +   + +L  QL Q  +LAEMYREQ + +E+EL +IREEGD  ++I+K RS K+  RLQ+M QRY+ LE+RRN+EV+G++TDI  LR++LK++EKQL+ VT+++G             + DLAIL  V+    ++  + G+L++LKA +YGLE ELR
Sbjct:   28 HTQKNRGDSTPLPPINERLAFLRPSRELLEYYRKKIAEFDEEHEDLVKQLEQYKATFEEQHKLQWEMRQREEEISELQKALSDMQVYLFQEREHVLRLYSENDRLKIRELEDRKKIQKLLALVGTSEGDVTYFHKEPPNKVTI-PQRAVQ--SGDPYARKLQRSGQAGTKQAPLKAPGKQDRSKEGKKEDPQIL------------LLQVEALQAQLEEQTRLSKEQIETLLEDRKVRVEETQVQHQRDQDKMKSMTDKLNKTQKLLYESTRDFLQLKFECRANEKSWMAEKDRLLRELDRCREQLALSSDPEQEREHEREILRLSLAEKAHRH-----------SHSEEVKSLTEQLAQAHRLAEMYREQCVTLEDELGKIREEGDVGREIFKERSDKVAKRLQLMTQRYEALEKRRNMEVEGYKTDIKLLRQRLKDVEKQLFKVTLNIGP------------DQDLAILDAVRQGNKKTQKIQGELRNLKAKIYGLENELR 492
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Xenopus
Match: pipox (pipecolic acid oxidase [Source:Xenbase;Acc:XB-GENE-1013122])

HSP 1 Score: 375.17 bits (962), Expect = 6.711e-124
Identity = 219/504 (43.45%), Postives = 325/504 (64.48%), Query Frame = 3 
Query:  108 NNSSNKNDSL----YDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGF------TTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKL-KTKESSAGQSGTGNKWIH---VDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLG-DQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            +   N+ DS      +  L  L+PSRELL++YR+K+A+   +H+ L+++LEQ   T + Q+ + W+++QRE+EIS+LQKALSDMQVYLF+ERE VLRLY+END+LKIREL+DRKKIQ LL L G ++ +VTYF K+PP+K  I P +AV   + D +      +   G  +  + A    + +   K+E   +L             +Q++ALQ+QLEEQTRL KEQ + L+EDR +R +ET+ Q  RDQ+K+++++DKL +TQ+LLY++T+DFL  + + R NEK W++EKD + R+L + +E  A  S    +  H   +   SL  KA               +   + +L  QL Q  +LAEMYREQ + +E+EL +IREEGD  ++I+K RS K+  RLQ+M QRY+ LE+RRN+EV+G++TDI  LR++LK++EKQL+ VT+++G DQ             DLAIL  V+    ++  + G+L++LKA +YGLE ELR
Sbjct:   66 HTQKNRGDSTPLPPINERLAFLRPSRELLEYYRKKIAEFDEEHEDLVKQLEQYKATFEEQHKLQWEMRQREEEISELQKALSDMQVYLFQEREHVLRLYSENDRLKIRELEDRKKIQKLLALVGTSEGDVTYFHKEPPNKVTI-PQRAVQ--SGDPYARKLQRSGQAGTKQAPLKAPGKQDRSKEGKKEDPQIL------------LLQVEALQAQLEEQTRLSKEQIETLLEDRKVRVEETQVQHQRDQDKMKSMTDKLNKTQKLLYESTRDFLQLKFECRANEKSWMAEKDRLLRELDRCREQLALSSDPEQEREHEREILRLSLAEKAHRH-----------SHSEEVKSLTEQLAQAHRLAEMYREQCVTLEDELGKIREEGDVGREIFKERSDKVAKRLQLMTQRYEALEKRRNMEVEGYKTDIKLLRQRLKDVEKQLFKVTLNIGPDQ-------------DLAILDAVRQGNKKTQKIQGELRNLKAKIYGLENELR 530
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Xenopus
Match: ENSXETT00000031469.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV460443.1:28419:41489:1 gene:ENSXETG00000009454.1 transcript:ENSXETT00000031469.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 294.664 bits (753), Expect = 7.547e-94
Identity = 180/440 (40.91%), Postives = 266/440 (60.45%), Query Frame = 3 
Query:  108 NNSSNKNDSL----YDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGF------TTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKL-KTKESSAGQSGTGNKWIH---VDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLE 1385
            +   N+ DS      +  L  L+PSRELL++YR+K+A+   +H+ L+++LEQ   T + Q+ + W+++QRE+EIS LQKALSDMQVYLF+ERE VLRLY+END+LKIREL+DRKKIQ LL L G ++ +VTYF K+PP+K  I P +AV   + D +      +   G  +  + A    + +   K+E   +L             +Q++ LQ QLEEQTRL KEQ + L+EDR +R +ET+ Q  RDQ+K+++++DK+     L     K               W++EKD + R+L + +E  A  S    +  H   +   SL  KA               +   + +L  QL Q  +LAEMYREQ + +E+EL +IREEGD  ++I+K RS K+  RLQ+M QRY+ LE+RRN+EV+G++TDI  LR++LK++E
Sbjct:   26 HTQKNRGDSTPLPPINERLAFLRPSRELLEYYRKKIAEFDEEHEDLVKQLEQYKATFEEQHKLQWEMRQREEEISKLQKALSDMQVYLFQEREHVLRLYSENDRLKIRELEDRKKIQKLLALVGTSEGDVTYFHKEPPNKVTI-PQRAVQ--SGDPYARKLQRSGQAGTKQAPLKAPGKQDRSKEGKKEDPQIL------------LLQVEELQVQLEEQTRLSKEQIETLLEDRKVRVEETQVQHQRDQDKMKSMTDKVGEISPLAEPMRKS--------------WMAEKDRLLRELDRCREQLALSSDPEQEREHEREILRLSLAEKA-----------SRHSHSEEVKSLTEQLAQAHRLAEMYREQCVTLEDELGKIREEGDVGREIFKERSDKVAKRLQLMTQRYEALEKRRNMEVEGYKTDIKLLRQRLKDVE 425
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Xenopus
Match: ENSXETT00000006867.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:10:15404877:15443635:1 gene:ENSXETG00000002884.1 transcript:ENSXETT00000006867.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 285.419 bits (729), Expect = 4.023e-90
Identity = 190/516 (36.82%), Postives = 287/516 (55.62%), Query Frame = 3 
Query:  108 NNSSNKNDSL----YDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGF------TTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRT----IRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKL-KTKESSAGQSGTGNKWIHVDPT------------SLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            +   N+ DS      +  L  L+PSRELL++YR+K+A+   +H  L+++LEQ   T + Q+ + W+++QRE+EIS+LQKALSDMQVYLF+ERE                 +D+KKIQ LL L G ++ +VTYF K+PP+K  I P +AV   + D +      +   G  +  + A    + +   K+E   +L             +Q+ ALQ+QLEEQTRL K+Q + L+EDR     +R +ET+ Q  +D  K+++++DK+     LLY               NEK W++EKD + R+L + +E  A            DP             SL  KA               +   + +L  QL Q  +LAEMYREQ + +E+EL +IREEGD  ++I+K  S K+  RLQ+M QRY+ LE+RRN+EV+G++TDI  LR++LK++EKQL+ VT+++G             + DLAIL  V+    ++  + G+L++LKA +YGLE ELR
Sbjct:    5 HTQKNRGDSTPLPPINERLAFLRPSRELLEYYRKKIAEFDEEHKDLVKQLEQYKATFEEQHKLQWEMRQREEEISELQKALSDMQVYLFQEREH----------------EDKKKIQKLLALVGTSEGDVTYFHKEPPNKVTI-PQRAVQ--SGDPYARKLQRSGQAGTKQAPLKAPGKQDRSKEGKKEDPQIL------------LLQVDALQAQLEEQTRLSKQQIETLLEDRKKPRKVRVEETQVQHHQD--KMKSMTDKVGEISPLLYITA------------NEKSWMAEKDRLLRELDRCREQLA---------FSTDPEQERENEREILRLSLAEKA-----------SRHSHSEEVKSLTEQLAQAHRLAEMYREQCVTLEDELGKIREEGDVGREIFKEHSDKVAKRLQLMTQRYEALEKRRNMEVEGYKTDIKLLRQRLKDVEKQLFKVTLNIGP------------DQDLAILDAVRQGNKKTQKIQGELRNLKAKIYGLENELR 443
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Xenopus
Match: ENSXETT00000036629.1 (coiled-coil domain-containing protein 77-like [Source:NCBI gene;Acc:101730700])

HSP 1 Score: 223.787 bits (569), Expect = 6.070e-68
Identity = 131/297 (44.11%), Postives = 197/297 (66.33%), Query Frame = 3 
Query:  699 VQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKL-KTKESSAGQSGTGNKWIH---VDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLG-DQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            +Q++ALQ+QLEEQTRL KEQ + L EDR +R +ET+ Q  RDQ+K+++++DKL +TQ+LLY++T+DFL  + + R NEK W++EKD + R+L + +E  A  S    +  H   +   SL  KA              ++ ++  +L  QL Q  +LAEMYREQ + +E+EL +IREEGD  ++I+K RS K+  RLQ+M QRY+ LE+RRN+EV+G++TDI  LR++LK++EKQL+ VT+++G DQ             DLAIL  V+    ++  + G+L++LKA + GLE ELR
Sbjct:   63 LQVEALQAQLEEQTRLSKEQIETL-EDRKVRVEETQVQHQRDQDKMKSMTDKLNKTQKLLYESTRDFLQLKFECRANEKSWMAEKDRLLRELDRCREQLALSSDPEQEREHEREILRLSLVEKA-------------SRHSHSEESLTEQLAQAHRLAEMYREQCVTLEDELGKIREEGDVGREIFKERSDKVAKRLQLMAQRYEALEKRRNMEVEGYKTDIKLLRQRLKDVEKQLFKVTLNIGPDQ-------------DLAILDAVRQGNKKTQKIQGELRNLKAKICGLENELR 332
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Mouse
Match: Ccdc77 (coiled-coil domain containing 77 [Source:MGI Symbol;Acc:MGI:1914450])

HSP 1 Score: 329.331 bits (843), Expect = 5.211e-107
Identity = 203/487 (41.68%), Postives = 297/487 (60.99%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVI--QPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKL-------KTKESSAGQSGTGNKWIHVDPTSLQSKAF-SEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTM--SLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            L  L PS+ELL++Y++K+A+  ++++ L++KLE   E  + Q+ + W+L+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP +  I  +  QA             G+         +        +E +S    +  +R+ E   +Q++ALQ+QL EQT+L +EQ + LMEDR IR +E + Q  R+QEKI  L+  L  TQELLY++TKDFL  + + +  EK W+ EKD +  K+       K KE   G+         V P   +S    +E+   +KD               +L Q++KL+ MY+EQ I +E ELA+IREE    ++I+K RS K+  RLQIM +RY+ LE RR LEV+GF+TDI +LR+KL++LE+ LY  TM  + GDQ             DLA+L EV+ +  R++ + G+LK+LK+ ++GLE  LR
Sbjct:   33 LAVLCPSQELLEYYQKKMANCESENEDLLKKLELYREACEEQHKLEWNLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGPDAGEVTYFHKEPPHRVSILQKTLQAAVACEPSASKADPGV---------SKRQVRIKDKEGIS----ERHQRDTEMLLLQVEALQAQLGEQTKLSREQVEGLMEDRRIRVEEIQVQHQRNQEKIMELTKSLHHTQELLYESTKDFLQLKFENQNKEKVWMLEKDHLMSKITQYRAQCKKKEDKLGK---------VVPILHESHHTQNEYIKSLKD---------------KLIQEKKLSNMYQEQCISLEEELARIREEEGVRREIFKDRSNKMGKRLQIMTKRYQALEHRRALEVEGFKTDIKSLRQKLRDLEQMLYKATMNNTHGDQ-------------DLAMLCEVRDSNRRAHKIQGELKNLKSKVFGLENALR 469
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Mouse
Match: Ccdc77 (coiled-coil domain containing 77 [Source:MGI Symbol;Acc:MGI:1914450])

HSP 1 Score: 328.946 bits (842), Expect = 1.469e-106
Identity = 203/487 (41.68%), Postives = 297/487 (60.99%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVI--QPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKL-------KTKESSAGQSGTGNKWIHVDPTSLQSKAF-SEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTM--SLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            L  L PS+ELL++Y++K+A+  ++++ L++KLE   E  + Q+ + W+L+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP +  I  +  QA             G+         +        +E +S    +  +R+ E   +Q++ALQ+QL EQT+L +EQ + LMEDR IR +E + Q  R+QEKI  L+  L  TQELLY++TKDFL  + + +  EK W+ EKD +  K+       K KE   G+         V P   +S    +E+   +KD               +L Q++KL+ MY+EQ I +E ELA+IREE    ++I+K RS K+  RLQIM +RY+ LE RR LEV+GF+TDI +LR+KL++LE+ LY  TM  + GDQ             DLA+L EV+ +  R++ + G+LK+LK+ ++GLE  LR
Sbjct:   51 LAVLCPSQELLEYYQKKMANCESENEDLLKKLELYREACEEQHKLEWNLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGPDAGEVTYFHKEPPHRVSILQKTLQAAVACEPSASKADPGV---------SKRQVRIKDKEGIS----ERHQRDTEMLLLQVEALQAQLGEQTKLSREQVEGLMEDRRIRVEEIQVQHQRNQEKIMELTKSLHHTQELLYESTKDFLQLKFENQNKEKVWMLEKDHLMSKITQYRAQCKKKEDKLGK---------VVPILHESHHTQNEYIKSLKD---------------KLIQEKKLSNMYQEQCISLEEELARIREEEGVRREIFKDRSNKMGKRLQIMTKRYQALEHRRALEVEGFKTDIKSLRQKLRDLEQMLYKATMNNTHGDQ-------------DLAMLCEVRDSNRRAHKIQGELKNLKSKVFGLENALR 487
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Mouse
Match: Ccdc77 (coiled-coil domain containing 77 [Source:MGI Symbol;Acc:MGI:1914450])

HSP 1 Score: 144.436 bits (363), Expect = 2.084e-40
Identity = 68/124 (54.84%), Postives = 99/124 (79.84%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAV 521
            L  L PS+ELL++Y++K+A+  ++++ L++KLE   E  + Q+ + W+L+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP + +
Sbjct:   33 LAVLCPSQELLEYYQKKMANCESENEDLLKKLELYREACEEQHKLEWNLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGPDAGEVTYFHKEPPHRIL 156
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Mouse
Match: Ccdc77 (coiled-coil domain containing 77 [Source:MGI Symbol;Acc:MGI:1914450])

HSP 1 Score: 145.976 bits (367), Expect = 2.495e-40
Identity = 68/123 (55.28%), Postives = 98/123 (79.67%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKA 518
            L  L PS+ELL++Y++K+A+  ++++ L++KLE   E  + Q+ + W+L+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP + 
Sbjct:   33 LAVLCPSQELLEYYQKKMANCESENEDLLKKLELYREACEEQHKLEWNLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGPDAGEVTYFHKEPPHRV 155

HSP 2 Score: 51.2174 bits (121), Expect = 5.786e-7
Identity = 25/44 (56.82%), Postives = 34/44 (77.27%), Query Frame = 3 
Query:  705 IQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKI 836
            ++ALQ+QL EQT+L +EQ + LMEDR IR +E + Q  R+QEKI
Sbjct:  155 VEALQAQLGEQTKLSREQVEGLMEDRRIRVEEIQVQHQRNQEKI 198
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Mouse
Match: Ccdc77 (coiled-coil domain containing 77 [Source:MGI Symbol;Acc:MGI:1914450])

HSP 1 Score: 105.916 bits (263), Expect = 1.364e-26
Identity = 49/90 (54.44%), Postives = 74/90 (82.22%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIR 419
            L  L PS+ELL++Y++K+A+  ++++ L++KLE   E  + Q+ + W+L+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IR
Sbjct:   33 LAVLCPSQELLEYYQKKMANCESENEDLLKKLELYREACEEQHKLEWNLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIR 122
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. UniProt/SwissProt
Match: sp|Q6DFC2|CCD77_XENLA (Coiled-coil domain-containing protein 77 OS=Xenopus laevis OX=8355 GN=ccdc77 PE=2 SV=1)

HSP 1 Score: 374.015 bits (959), Expect = 3.224e-123
Identity = 211/488 (43.24%), Postives = 317/488 (64.96%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSV------GIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKL-KTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQ-----YKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLG-DQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            L  L+PSRELL++YR+K+A+   +H+ L+++LEQ   T + Q+ + W+++QRE+EI++LQKALSDMQVYLF+ERE VLRLY+END+LKIREL+DRKKIQ LL L G ++ ++TYF K+PPSK  I P + V   + D F   V      G+ +  + A    +     ++E   +L             +Q++ALQ+QLEEQTRL KEQ + L+EDR +R +E + Q  RDQ+K++A++DKL +TQ+LLY++T+DFL  + + R NEK W++EKD + R+L + +E  A           +DP   +          ++    E+     +   + +L  QL Q  +L+EMYREQ + +E+EL +IREEGD  ++I+K RS K+  RLQ+M QRY+ LE+RRN+EV+G++TDI  LR++LK++EKQL+ VT+++G DQ             DLAIL  V+    ++  + G+L++LKA +YGLE ELR
Sbjct:   44 LAFLRPSRELLEYYRKKIAEFDEEHEDLVKRLEQYKATYEEQHKLQWEMRQREEEIAELQKALSDMQVYLFQEREHVLRLYSENDRLKIRELEDRKKIQKLLALVGTSEGDITYFHKEPPSKVTI-PQRTVQ--SGDPFDRKVQRSGRAGVKQVPLKAPGKQDRTKAAEKEDPQIL------------LLQVEALQAQLEEQTRLSKEQIETLLEDRKVRMEEAQVQHQRDQDKMKAMTDKLNKTQKLLYESTRDFLQLKFECRANEKSWMAEKDRLLRELDRCREQLA---------FSIDPEQEREHEREHEREILRLSLAEKATRSSHSEEVKSLTEQLAQAHRLSEMYREQCVTLEDELGRIREEGDVGREIFKERSDKVAKRLQLMTQRYEALEKRRNMEVEGYKTDIKLLRQRLKDVEKQLFKVTLNIGPDQ-------------DLAILDAVRQGNKKTQKIQGELRNLKAKIYGLENELR 494
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. UniProt/SwissProt
Match: sp|Q9BR77|CCD77_HUMAN (Coiled-coil domain-containing protein 77 OS=Homo sapiens OX=9606 GN=CCDC77 PE=1 SV=1)

HSP 1 Score: 333.183 bits (853), Expect = 1.845e-107
Identity = 205/481 (42.62%), Postives = 301/481 (62.58%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVI--QPNQAVTLV---TSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQS-KAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            L  L PS+ELL++Y++K+A+   +++ L++KLE   E  + Q+ +  DL+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP K  I  +  QAV       S  F     I+++  +  R  ++            EH   +R++++  +Q++ALQ+QL EQT+L +EQ + L+EDR I  +E + Q  R+Q KI+ L+  L  TQELLY++TKDFL  RS+ +  EK W+ EKD +  K+K       +    +K   V P   +S  A SE+   +KD               +L Q++KL+ MY+EQ I +E ELA+IREE    ++I+K R+ K+  RLQIM +RY+ LERRR LEV+GF+TDI  LR+KLK+LE+ LY  T++               N DLA+L EV+ +  R++ + G+LK+LK+ ++GLE ELR
Sbjct:   49 LAKLHPSKELLEYYQKKMAECEAENEDLLKKLELYKEACEGQHKLECDLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGTDAGEVTYFCKEPPHKVTILQKTIQAVGECEQSESSAFKADPKISKRRPSRERKESS------------EH--YQRDIQTLILQVEALQAQLGEQTKLSREQIEGLIEDRRIHLEEIQVQHQRNQNKIKELTKNLHHTQELLYESTKDFLQLRSENQNKEKSWMLEKDNLMSKIKQYRVQCKKK--EDKIGKVLPVMHESHHAQSEYIKSLKD---------------KLVQEKKLSNMYQEQCISLEEELARIREEEGMRREIFKDRTNKMGKRLQIMTKRYEALERRRILEVEGFKTDIKVLRQKLKDLEQMLYKATVN------------ARANQDLALLCEVRDSNRRAHKIQGELKNLKSKVFGLENELR 486
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. UniProt/SwissProt
Match: sp|Q9CZH8|CCD77_MOUSE (Coiled-coil domain-containing protein 77 OS=Mus musculus OX=10090 GN=Ccdc77 PE=1 SV=1)

HSP 1 Score: 328.946 bits (842), Expect = 1.027e-105
Identity = 203/487 (41.68%), Postives = 297/487 (60.99%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVI--QPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKL-------KTKESSAGQSGTGNKWIHVDPTSLQSKAF-SEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTM--SLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            L  L PS+ELL++Y++K+A+  ++++ L++KLE   E  + Q+ + W+L+QRE+EI++LQKALSDMQV LF+ERE VLRLY+END+L+IREL+D+KKIQ+LL L G    EVTYF K+PP +  I  +  QA             G+         +        +E +S    +  +R+ E   +Q++ALQ+QL EQT+L +EQ + LMEDR IR +E + Q  R+QEKI  L+  L  TQELLY++TKDFL  + + +  EK W+ EKD +  K+       K KE   G+         V P   +S    +E+   +KD               +L Q++KL+ MY+EQ I +E ELA+IREE    ++I+K RS K+  RLQIM +RY+ LE RR LEV+GF+TDI +LR+KL++LE+ LY  TM  + GDQ             DLA+L EV+ +  R++ + G+LK+LK+ ++GLE  LR
Sbjct:   51 LAVLCPSQELLEYYQKKMANCESENEDLLKKLELYREACEEQHKLEWNLQQREEEIAELQKALSDMQVCLFQEREHVLRLYSENDRLRIRELEDKKKIQNLLALVGPDAGEVTYFHKEPPHRVSILQKTLQAAVACEPSASKADPGV---------SKRQVRIKDKEGIS----ERHQRDTEMLLLQVEALQAQLGEQTKLSREQVEGLMEDRRIRVEEIQVQHQRNQEKIMELTKSLHHTQELLYESTKDFLQLKFENQNKEKVWMLEKDHLMSKITQYRAQCKKKEDKLGK---------VVPILHESHHTQNEYIKSLKD---------------KLIQEKKLSNMYQEQCISLEEELARIREEEGVRREIFKDRSNKMGKRLQIMTKRYQALEHRRALEVEGFKTDIKSLRQKLRDLEQMLYKATMNNTHGDQ-------------DLAMLCEVRDSNRRAHKIQGELKNLKSKVFGLENALR 487
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. TrEMBL
Match: A0A1I8GS18 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 424.476 bits (1090), Expect = 9.257e-141
Identity = 224/482 (46.47%), Postives = 330/482 (68.46%), Query Frame = 3 
Query:  159 LQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMP----------QNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            +QPS+ELLD+YRRKV DL  DH  L  +L++ +    +Q+ + W+L+QREDEI++LQKALSD+QVYLF+ER+QVLRLYAEND+LKI+EL DRKK+ HLL++SG++ SEVTYF+K+PP  AV+ P +    V     + +  +        R         +++V  LEH++V RE +S ++Q+ +LQSQLEEQ +L KEQ +ALMEDR IR  E ++ R RDQ+KI+ L+DKLKR QE+L D+TKD L QR  +++ EK WI EK  + ++++T+      + +  + +      +  +A + W    +    ++ +  +  L+YQL+QQ +LA+MYREQV++ E++L ++REE ++  D+YK R++KI  RLQ+MNQRY +LERRRNLEV+GF+TDI  LR+KL+ +E+QLY +T+ LGD +++    L P            +D+A+L+EV+ T+ RS  L  +LK LKAMMYGLE ELR
Sbjct:    1 MQPSKELLDYYRRKVQDLDADHQQLEHRLQEFSAACGDQHRLQWELRQREDEIAELQKALSDLQVYLFQERDQVLRLYAENDRLKIKELQDRKKMAHLLQISGVSDSEVTYFLKEPPDVAVV-PQKLPGQVQQAAKSANPQL-------LRAAQALPEALRKTVPALEHEAVLRECDSLRLQLHSLQSQLEEQAKLSKEQVNALMEDRRIRAMEADSSRDRDQDKIKELADKLKRAQEMLQDSTKDLLEQRKVHKQAEKTWIQEKARLLQEIETRRPRYQNTPSERERLR---QLVSGQAEASWAKAEQSAVVDELRQQVKTLEYQLQQQTELADMYREQVVQAEDQLCRLREERESAADLYKDRASKIGGRLQLMNQRYAELERRRNLEVEGFKTDIQQLRQKLRGVERQLYKLTIGLGDSVTNGARLLRPAGGGAADVGADGVDMALLKEVRATSGRSKQLGDELKQLKAMMYGLENELR 471
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. TrEMBL
Match: A0A1I8HB63 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 426.787 bits (1096), Expect = 1.252e-140
Identity = 228/497 (45.88%), Postives = 335/497 (67.40%), Query Frame = 3 
Query:  114 SSNKNDSLYDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMP----------QNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            S    D L  + L  +QPS+ELLD+YRRKV DL  DH  L  +L++ +    +Q+ + W+L+QREDEI++LQKALSD+QVYLF+ER+QVLRLYAEND+LKI+EL DRKK+ HLL++SG++ SEVTYF+K+PP  AV+ P +    V     + +  +        R         +++V  LEH++V RE +S ++Q+ +LQSQLEEQ +L KEQ +ALMEDR IR  E ++ R RDQ+KI+ L+DKLKR QE+L D+TKD L QR  +++ EK WI EK  + ++++T+      + +  + +      +  +A + W    +    ++ +  +  L+YQL+QQ +LA+MYREQV++ E++L ++REE ++  D+YK R++KI  RLQ+MNQRY +LERRRNLEV+GF+TDI  LR+KL+ +E+QLY +T+ LGD +++    L P            +D+A+L+EV+ T+ RS  L  +LK LKAMMYGLE ELR
Sbjct:   65 SPTPRDDL-GARLALMQPSKELLDYYRRKVQDLDADHQQLEHRLQEFSAACGDQHRLQWELRQREDEIAELQKALSDLQVYLFQERDQVLRLYAENDRLKIKELQDRKKMAHLLQISGVSDSEVTYFLKEPPDVAVV-PQKLPGQVQQAAKSANPQL-------LRAAQALPEALRKTVPALEHEAVLRECDSLRLQLHSLQSQLEEQAKLSKEQVNALMEDRRIRAMEADSSRDRDQDKIKELADKLKRAQEMLQDSTKDLLEQRKVHKQAEKTWIQEKARLLQEIETRRPRYQNTPSERERLR---QLVSGQAEASWAKAEQSAVVDELRQQVKTLEYQLQQQTELADMYREQVVQAEDQLCRLREERESAADLYKDRASKIGGRLQLMNQRYAELERRRNLEVEGFKTDIQQLRQKLRGVERQLYKLTIGLGDSVTNGARLLRPAGGGAADVGADGVDMALLKEVRATSGRSKQLGDELKQLKAMMYGLENELR 549
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. TrEMBL
Match: A0A1I8JHI9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 426.787 bits (1096), Expect = 1.426e-140
Identity = 228/497 (45.88%), Postives = 335/497 (67.40%), Query Frame = 3 
Query:  114 SSNKNDSLYDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMP----------QNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            S    D L  + L  +QPS+ELLD+YRRKV DL  DH  L  +L++ +    +Q+ + W+L+QREDEI++LQKALSD+QVYLF+ER+QVLRLYAEND+LKI+EL DRKK+ HLL++SG++ SEVTYF+K+PP  AV+ P +    V     + +  +        R         +++V  LEH++V RE +S ++Q+ +LQSQLEEQ +L KEQ +ALMEDR IR  E ++ R RDQ+KI+ L+DKLKR QE+L D+TKD L QR  +++ EK WI EK  + ++++T+      + +  + +      +  +A + W    +    ++ +  +  L+YQL+QQ +LA+MYREQV++ E++L ++REE ++  D+YK R++KI  RLQ+MNQRY +LERRRNLEV+GF+TDI  LR+KL+ +E+QLY +T+ LGD +++    L P            +D+A+L+EV+ T+ RS  L  +LK LKAMMYGLE ELR
Sbjct:   65 SPTPRDDL-GARLALMQPSKELLDYYRRKVQDLDADHQQLEHRLQEFSAACGDQHRLQWELRQREDEIAELQKALSDLQVYLFQERDQVLRLYAENDRLKIKELQDRKKMAHLLQISGVSDSEVTYFLKEPPDVAVV-PQKLPGQVQQAAKSANPQL-------LRAAQALPEALRKTVPALEHEAVLRECDSLRLQLHSLQSQLEEQAKLSKEQVNALMEDRRIRAMEADSSRDRDQDKIKELADKLKRAQEMLQDSTKDLLEQRKVHKQAEKTWIQEKARLLQEIETRRPRYQNTPSERERLR---QLVSGQAEASWAKAEQSAVVDELRQQVKTLEYQLQQQTELADMYREQVVQAEDQLCRLREERESAADLYKDRASKIGGRLQLMNQRYAELERRRNLEVEGFKTDIQQLRQKLRGVERQLYKLTIGLGDSVTNGARLLRPAGGGAADVGADGVDMALLKEVRATSGRSKQLGDELKQLKAMMYGLENELR 549
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. TrEMBL
Match: A0A267EDL4 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012048g1 PE=4 SV=1)

HSP 1 Score: 426.787 bits (1096), Expect = 1.627e-140
Identity = 228/497 (45.88%), Postives = 335/497 (67.40%), Query Frame = 3 
Query:  114 SSNKNDSLYDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMP----------QNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            S    D L  + L  +QPS+ELLD+YRRKV DL  DH  L  +L++ +    +Q+ + W+L+QREDEI++LQKALSD+QVYLF+ER+QVLRLYAEND+LKI+EL DRKK+ HLL++SG++ SEVTYF+K+PP  AV+ P +    V     + +  +        R         +++V  LEH++V RE +S ++Q+ +LQSQLEEQ +L KEQ +ALMEDR IR  E ++ R RDQ+KI+ L+DKLKR QE+L D+TKD L QR  +++ EK WI EK  + ++++T+      + +  + +      +  +A + W    +    ++ +  +  L+YQL+QQ +LA+MYREQV++ E++L ++REE ++  D+YK R++KI  RLQ+MNQRY +LERRRNLEV+GF+TDI  LR+KL+ +E+QLY +T+ LGD +++    L P            +D+A+L+EV+ T+ RS  L  +LK LKAMMYGLE ELR
Sbjct:   63 SPTPRDDL-GARLALMQPSKELLDYYRRKVQDLDADHQQLEHRLQEFSAACGDQHRLQWELRQREDEIAELQKALSDLQVYLFQERDQVLRLYAENDRLKIKELQDRKKMAHLLQISGVSDSEVTYFLKEPPDVAVV-PQKLPGQVQQAAKSANPQL-------LRAAQALPEALRKTVPALEHEAVLRECDSLRLQLHSLQSQLEEQAKLSKEQVNALMEDRRIRAMEADSSRDRDQDKIKELADKLKRAQEMLQDSTKDLLEQRKVHKQAEKTWIQEKARLLQEIETRRPRYQNTPSERERLR---QLVSGQAEASWAKAEQSAVVDELRQQVKTLEYQLQQQTELADMYREQVVQAEDQLCRLREERESAADLYKDRASKIGGRLQLMNQRYAELERRRNLEVEGFKTDIQQLRQKLRGVERQLYKLTIGLGDSVTNGARLLRPAGGGAADVGADGVDMALLKEVRATSGRSKQLGDELKQLKAMMYGLENELR 547
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. TrEMBL
Match: A0A267G096 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012048g4 PE=4 SV=1)

HSP 1 Score: 426.402 bits (1095), Expect = 1.755e-140
Identity = 228/497 (45.88%), Postives = 335/497 (67.40%), Query Frame = 3 
Query:  114 SSNKNDSLYDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMP----------QNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            S    D L  + L  +QPS+ELLD+YRRKV DL  DH  L  +L++ +    +Q+ + W+L+QREDEI++LQKALSD+QVYLF+ER+QVLRLYAEND+LKI+EL DRKK+ HLL++SG++ SEVTYF+K+PP  AV+ P +    V     + +  +        R         +++V  LEH++V RE +S ++Q+ +LQSQLEEQ +L KEQ +ALMEDR IR  E ++ R RDQ+KI+ L+DKLKR QE+L D+TKD L QR  +++ EK WI EK  + ++++T+      + +  + +      +  +A + W    +    ++ +  +  L+YQL+QQ +LA+MYREQV++ E++L ++REE ++  D+YK R++KI  RLQ+MNQRY +LERRRNLEV+GF+TDI  LR+KL+ +E+QLY +T+ LGD +++    L P            +D+A+L+EV+ T+ RS  L  +LK LKAMMYGLE ELR
Sbjct:   63 SPTPRDDL-GARLALMQPSKELLDYYRRKVQDLDADHQQLEHRLQEFSAACGDQHRLQWELRQREDEIAELQKALSDLQVYLFQERDQVLRLYAENDRLKIKELQDRKKMAHLLQISGVSDSEVTYFLKEPPDVAVV-PQKLPGQVQQAAKSANPQL-------LRAAQALPEALRKTVPALEHEAVLRECDSLRLQLHSLQSQLEEQAKLSKEQVNALMEDRRIRAMEADSSRDRDQDKIKELADKLKRAQEMLQDSTKDLLEQRKVHKQAEKTWIQEKARLLQEIETRRPRYQNTPSERERLR---QLVSGQAEASWAKAEQSAVVDELRQQVKTLEYQLQQQTELADMYREQVVQAEDQLCRLREERESAADLYKDRASKIGGRLQLMNQRYAELERRRNLEVEGFKTDIQQLRQKLRGVERQLYKLTIGLGDSVTNGARLLRPAGGGAADVGADGVDMALLKEVRATSGRSKQLGDELKQLKAMMYGLENELR 547
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Cavefish
Match: ccdc77 (coiled-coil domain containing 77 [Source:NCBI gene;Acc:103035413])

HSP 1 Score: 377.481 bits (968), Expect = 8.863e-126
Identity = 216/480 (45.00%), Postives = 315/480 (65.62%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKL-----KTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            L  L+PSRELL+FYR+KVA    +HD L++ LE+   T+++Q+ + W+++QRE+EI++LQKALSDMQVYLF+EREQ LRLYAEND+LKI+EL+DRKKIQHLL L G    E+TYF ++PP K  I P + +   T +   T+          ++  + N +TK E          K++ ++  +Q++ALQ+QLEEQTRL KEQ +AL+EDR I  +E + Q  RDQE+I AL++KL+RTQ LLY++T+D+L  + + R +EK W+ EKD + R+L     + K+ +     +    +   PT+  S                 ++  I  L  +L+Q  KLA+MYREQ + +E ++AQIREEGD  ++I+K RS KI  RLQ+M QRY+ LE+RR +EV+GF+ DI +LR+KLK++EKQL+ VT+++G             + DLAIL+EV+ + AR+  + G+LK LKA +YGLE ELR
Sbjct:   29 LAYLRPSRELLEFYRQKVAQFDEEHDDLLQLLEKYRSTTEDQHKLQWEVRQREEEIAELQKALSDMQVYLFQEREQALRLYAENDRLKIKELEDRKKIQHLLALVGPDVGEITYFHREPPHKVAI-PQKKLQPRTQEFAKTAKPKLGSVQEGSKRLSKNGDTKSE--------QYKKDNQTLLLQVEALQAQLEEQTRLSKEQVEALLEDRRIHAEERQVQHQRDQERITALTEKLQRTQNLLYESTRDYLQLKFESRGHEKSWMGEKDKLLRELDSCQERLKDFADRPGPSAAPLLLSQPTTESSHM---------------HREEIRALQEELKQAHKLADMYREQCVGLETDVAQIREEGDVGREIFKERSDKIAKRLQLMTQRYEALEKRRAMEVEGFKNDIKHLRQKLKDVEKQLFKVTLNVGP------------DQDLAILQEVRQSNARTKKIQGELKTLKAKIYGLENELR 472
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Sea Lamprey
Match: ccdc77 (coiled-coil domain containing 77 [Source:ZFIN;Acc:ZDB-GENE-050913-54])

HSP 1 Score: 362.073 bits (928), Expect = 3.066e-120
Identity = 210/481 (43.66%), Postives = 314/481 (65.28%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKES--SAGQSGT---GNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELRQ 1577
            L  L+PSRELL++YR+K+A+   +H+ ++++L+    T + Q+ + W+++QRE+EI +LQKALSDMQVYLF+ERE VLRLY+END+LKIREL+DRKKIQHLL L G    EVTYF K+PP K +I P ++     S    ++     +  + T+  +       +S +  E    +R+ +   +Q++ L +QLEEQT+L KEQ ++L+EDR IR +E + Q+ RDQEKI AL++KL+ T  LLY++T+DFL  + + R NEK+W++EKD + ++L       S GQ GT   G   I   P+  Q +A          Q+ E++K     L  +L+Q  +LAEM+REQ + +E+EL++IREEGD  K+I+K RS K+  RL+++ QRY+ LE+RR +EV+GF+ DI  LR++LK++EKQL+ VT+ +G             N DLAIL EV+ +  R+  + G+L  LKA +YGLE +LR 
Sbjct:   45 LAFLRPSRELLEYYRKKIAEFDGEHEDMLKRLDAYKGTYEEQHKLQWEMRQREEEIGELQKALSDMQVYLFQEREHVLRLYSENDRLKIRELEDRKKIQHLLALVGPDTGEVTYFYKEPPHKVII-PQKSTK---SSQLLSAKENRPQGKSGTKRPSGKPTNGADSPTTPER--YQRDKQMLVLQVETLSAQLEEQTKLAKEQVESLLEDRRIRVEEMQVQQRRDQEKINALTEKLQETHSLLYESTRDFLQLKYEGRANEKRWMAEKDQLLQELDACRDRLSRGQ-GTEEDGPPDIFTPPSERQRRA----------QQGEEFKG----LQEELKQAHRLAEMFREQCVSLEDELSRIREEGDVGKEIFKDRSDKMAKRLRMVTQRYEALEKRRAMEVEGFKNDIKLLRQRLKDVEKQLFRVTLGVGP------------NQDLAILHEVRDSNTRTRKIQGELHRLKAKIYGLEGDLRH 492
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Nematostella
Match: EDO34896 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN36])

HSP 1 Score: 379.407 bits (973), Expect = 3.054e-127
Identity = 213/476 (44.75%), Postives = 303/476 (63.66%), Query Frame = 3 
Query:  150 LVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELRQ 1577
            L +L+PS+ELL++YR+K+A+   +H+ ++ KLE+   T + Q+   W+L+QRE+EIS+LQKALSDMQVYLF+ERE VLRLYAEND+LKIREL+DRKKIQHLL LS  T+ E+TYF K PP+KAVI+ N+  T          +                 +  Q+  +LL             +QI++LQ+QLEEQT+  KEQTDAL+EDR +R +E  AQR RD +KI+ L DKL  TQ LLY++TKDFL  + + R  E+ W+ ++D + ++++        SG                +  E +G    +  +   + +++L  QLEQ QKLAEMYREQ I +E EL++IRE+ D +K+I+K RS K+  RL ++NQRY+ LE+RR LEV+GF+ DI  LR KLK++EKQL+ VT+++GD            N D  +LR V+ TA RS HL G+L +LKA +Y +E ++R 
Sbjct:   23 LGHLRPSKELLEYYRKKIAEYDGEHEQMVHKLERYKCTYEEQHKSQWELRQREEEISELQKALSDMQVYLFQEREHVLRLYAENDRLKIRELEDRKKIQHLLSLSKATEPEITYFHKQPPAKAVIKQNKLETWTKRPATEQEI--------YGNLRPAPRSPSQDRQTLL-------------LQIESLQAQLEEQTKTAKEQTDALLEDRRVRMEEQHAQRERDADKIKTLQDKLHNTQSLLYESTKDFLELKYELRAKERHWMVDRDRLIQEIEHLREELDISGVS--------------SILEVSGGEPMEPRQAQMHAVHSLKDQLEQSQKLAEMYREQCIGLEEELSRIREKTDVSKEIFKERSEKMGKRLTLLNQRYEALEKRRALEVEGFKNDIKQLRNKLKDVEKQLFKVTVNIGD------------NYDEEVLRNVRRTAGRSKHLVGELHNLKAKIYSIENDIRH 451
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Medaka
Match: ccdc77 (coiled-coil domain containing 77 [Source:NCBI gene;Acc:101163247])

HSP 1 Score: 193.356 bits (490), Expect = 3.635e-56
Identity = 111/233 (47.64%), Postives = 150/233 (64.38%), Query Frame = 3 
Query:  168 SRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRT 866
            SRELL+FYR+K+A    +++ L++ LE+      +Q+ + W+L+QRE E+++LQ ALSDMQVYLF+EREQ LRLYAEND+LKIRE +DRKKIQHLL L G    EVTYF ++PP K    P  +   V  D    + G                     S   LE    K + ++  +Q++ALQ+QLEEQTRL KEQ +AL+EDR I+ +E +AQ+ RDQE+I AL+DKL  T
Sbjct:    1 SRELLEFYRQKIAQYDGENEELLQMLEKHRSIMDDQHKLQWELRQREGEVAELQNALSDMQVYLFQEREQSLRLYAENDRLKIREFEDRKKIQHLLALVGPDAGEVTYFHREPPHKV---PYSSQLPVQPDCSAANGG---------------------SAEALE--KFKDDNQTLLLQVEALQAQLEEQTRLAKEQVEALLEDRKIKTEEAQAQQRRDQERIAALNDKLVET 207

HSP 2 Score: 145.206 bits (365), Expect = 2.952e-38
Identity = 86/211 (40.76%), Postives = 129/211 (61.14%), Query Frame = 3 
Query:  966 RKLKTKESSAGQ-------SGTGNKWIHVD-PTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELR 1574
            RK+KT+E+ A Q       +   +K +  D P S +++        ++   +  +      L  +L+Q  +LAEMYREQ I ME +L+QIREEGD  ++I++ RS K+  RLQ+M QRY+ LE+RR +EV+GF+TD+  LR+KLK++EKQL  VT+++G             N DLA+L EV+ + +R+  L  +L  LKA +YGLE ELR
Sbjct:  179 RKIKTEEAQAQQRRDQERIAALNDKLVETDFPVSPETR--------LRIILDSAFPTQHQRLPEELKQAHRLAEMYREQCIAMETQLSQIREEGDVGREIFQERSEKMAKRLQVMTQRYEALEKRRAMEVEGFKTDLKQLRQKLKDVEKQLIKVTLNVG------------ANQDLAVLHEVRQSNSRTKKLQEELMRLKAKIYGLENELR 369
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Planmine SMEST
Match: SMESG000045184.1 (SMESG000045184.1)

HSP 1 Score: 978.778 bits (2529), Expect = 0.000e+0
Identity = 505/507 (99.61%), Postives = 506/507 (99.80%), Query Frame = 3 
Query:   57 MSKKQSNNDNMLKIRMPNNSSNKNDSLYDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELRQ 1577
            MSKKQSNNDNMLKIRMPNNSSNKNDSLYDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVG ARKNVTATRNTNNNANTKQ+SVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELRQ
Sbjct:    1 MSKKQSNNDNMLKIRMPNNSSNKNDSLYDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGSARKNVTATRNTNNNANTKQDSVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVTMSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYGLERELRQ 507
[Close]
BLAST of Coiled-coil domain-containing protein 77 vs. Planmine SMEST
Match: SMESG000045184.1 (SMESG000045184.1)

HSP 1 Score: 857.055 bits (2213), Expect = 0.000e+0
Identity = 446/449 (99.33%), Postives = 448/449 (99.78%), Query Frame = 3 
Query:   57 MSKKQSNNDNMLKIRMPNNSSNKNDSLYDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGIXXXXXXXXXXXXXXXXXXQESVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMV 1403
            MSKKQSNNDNMLKIRMPNNSSNKNDSLYDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVG ARKNVTATRNTNNNANTKQ+SVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYM+
Sbjct:    1 MSKKQSNNDNMLKIRMPNNSSNKNDSLYDSTLVNLQPSRELLDFYRRKVADLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVYLFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDPPSKAVIQPNQAVTLVTSDGFTTSVGSARKNVTATRNTNNNANTKQDSVSLLEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETEAQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKDLMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQYKNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRSTKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMM 449
The following BLAST results are available for this feature:
BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CCDC773.587e-10842.62coiled-coil domain containing 77 [Source:HGNC Symb... [more]
CCDC773.587e-10842.62coiled-coil domain containing 77 [Source:HGNC Symb... [more]
CCDC773.587e-10842.62coiled-coil domain containing 77 [Source:HGNC Symb... [more]
CCDC773.842e-10842.62coiled-coil domain containing 77 [Source:HGNC Symb... [more]
CCDC771.748e-8742.64coiled-coil domain containing 77 [Source:HGNC Symb... [more]
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ccdc777.430e-11443.42coiled-coil domain containing 77 [Source:ZFIN;Acc:... [more]
ccdc774.669e-5845.80coiled-coil domain containing 77 [Source:ZFIN;Acc:... [more]
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pipox7.914e-12543.14pipecolic acid oxidase [Source:Xenbase;Acc:XB-GENE... [more]
pipox6.711e-12443.45pipecolic acid oxidase [Source:Xenbase;Acc:XB-GENE... [more]
ENSXETT00000031469.17.547e-9440.91pep primary_assembly:Xenopus_tropicalis_v9.1:KV460... [more]
ENSXETT00000006867.14.023e-9036.82pep primary_assembly:Xenopus_tropicalis_v9.1:10:15... [more]
ENSXETT00000036629.16.070e-6844.11coiled-coil domain-containing protein 77-like [Sou... [more]
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ccdc775.211e-10741.68coiled-coil domain containing 77 [Source:MGI Symbo... [more]
Ccdc771.469e-10641.68coiled-coil domain containing 77 [Source:MGI Symbo... [more]
Ccdc772.084e-4054.84coiled-coil domain containing 77 [Source:MGI Symbo... [more]
Ccdc772.495e-4055.28coiled-coil domain containing 77 [Source:MGI Symbo... [more]
Ccdc771.364e-2654.44coiled-coil domain containing 77 [Source:MGI Symbo... [more]
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BLAST of Coiled-coil domain-containing protein 77 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|Q6DFC2|CCD77_XENLA3.224e-12343.24Coiled-coil domain-containing protein 77 OS=Xenopu... [more]
sp|Q9BR77|CCD77_HUMAN1.845e-10742.62Coiled-coil domain-containing protein 77 OS=Homo s... [more]
sp|Q9CZH8|CCD77_MOUSE1.027e-10541.68Coiled-coil domain-containing protein 77 OS=Mus mu... [more]
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BLAST of Coiled-coil domain-containing protein 77 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8GS189.257e-14146.47Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8HB631.252e-14045.88Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8JHI91.426e-14045.88Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267EDL41.627e-14045.88Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A267G0961.755e-14045.88Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ccdc778.863e-12645.00coiled-coil domain containing 77 [Source:NCBI gene... [more]
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ccdc773.066e-12043.66coiled-coil domain containing 77 [Source:ZFIN;Acc:... [more]
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO348963.054e-12744.75Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Coiled-coil domain-containing protein 77 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ccdc773.635e-5647.64coiled-coil domain containing 77 [Source:NCBI gene... [more]
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BLAST of Coiled-coil domain-containing protein 77 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000045184.10.000e+099.61SMESG000045184.1[more]
SMESG000045184.10.000e+099.33SMESG000045184.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022246 ID=SMED30022246|Name=Coiled-coil domain-containing protein 77|organism=Schmidtea mediterranea sexual|type=transcript|length=1630bp
CTTAGCAATTAATTATTTTTAAATTGGTTTTTTTAAAGTTTTTTTAATGT
TAAAATATGTCTAAAAAGCAAAGTAATAATGATAATATGTTAAAGATTCG
AATGCCAAATAATTCTTCCAATAAAAACGATTCCCTCTATGATTCTACTT
TAGTGAATCTGCAGCCATCTAGAGAATTGTTAGATTTCTATCGTCGAAAA
GTGGCGGATTTGACTACTGACCATGATGCATTAATGCGTAAATTAGAACA
GCTGAATGAAACAAGTCAAAATCAGTATTCAATTGTCTGGGATCTAAAAC
AACGAGAAGATGAAATATCTGATCTTCAAAAGGCATTATCTGATATGCAG
GTGTATTTGTTCAAAGAACGCGAACAAGTTCTTCGTTTATATGCAGAAAA
TGATAAATTGAAGATTAGGGAATTGGACGATCGAAAAAAAATCCAACATC
TATTAGAATTGAGCGGCTTGACACAGTCAGAAGTGACATATTTTATCAAG
GATCCCCCATCTAAAGCCGTTATTCAACCAAACCAAGCTGTGACACTCGT
TACATCAGATGGATTCACCACAAGTGTGGGAATTGCCCGGAAAAACGTGA
CAGCAACCAGAAACACAAACAACAATGCAAATACCAAGCAGGAATCGGTT
TCTTTGCTCGAACATCAGTCAGTGAAACGGGAACTGGAGTCGTACAAAGT
GCAAATCCAGGCGCTACAATCGCAACTGGAGGAGCAGACCCGGCTGTACA
AGGAGCAGACAGACGCCCTGATGGAGGACCGCACCATCCGCCAGCAGGAA
ACCGAGGCCCAACGCAGCCGGGACCAGGAAAAAATTCAAGCTCTCTCAGA
CAAATTGAAAAGAACTCAAGAATTACTATATGATAATACCAAAGATTTCC
TATCTCAACGCAGCCAATACAGAGAAAATGAAAAACAATGGATATCGGAA
AAGGATTTAATGTTTAGAAAGTTAAAAACCAAGGAATCATCAGCTGGACA
ATCGGGAACCGGAAATAAGTGGATCCATGTCGATCCAACCAGTCTACAAA
GCAAGGCGTTCAGTGAATGGACTGGTCAAATGAAAGACCAAAAAGAAGAG
CAGTATAAAAATACAATCAACAATTTAGACTACCAATTGGAACAGCAACA
AAAACTGGCGGAAATGTATCGGGAACAAGTCATAGAAATGGAGAATGAAC
TGGCACAGATCCGAGAAGAAGGCGACGCAACGAAAGACATTTATAAAACA
CGATCGACAAAGATCAACGATCGGCTGCAAATTATGAATCAAAGATATAA
AGATCTAGAACGACGGCGAAATTTGGAAGTTCAAGGATTCCAGACAGATA
TTGGCAATTTGCGTAAGAAATTGAAAAATCTAGAAAAGCAATTATATATG
GTAACCATGAGTCTTGGTGACCAGATCTCGTCCAGTGGACCGAATCTGAT
GCCGCAGAATCTTGATTTAGCTATTTTGCGCGAAGTGAAGCACACGGCTG
CCAGATCAAATCATTTGTCAGGTCAGCTGAAAGATTTGAAAGCCATGATG
TATGGACTGGAAAGAGAACTGAGACAACTGTGATTAAAATACAAAAATCT
AAATTCTTTGAAAAAAAAAGATCGGAAGAG
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protein sequence of SMED30022246-orf-1

>SMED30022246-orf-1 ID=SMED30022246-orf-1|Name=SMED30022246-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=509bp
MSKKQSNNDNMLKIRMPNNSSNKNDSLYDSTLVNLQPSRELLDFYRRKVA
DLTTDHDALMRKLEQLNETSQNQYSIVWDLKQREDEISDLQKALSDMQVY
LFKEREQVLRLYAENDKLKIRELDDRKKIQHLLELSGLTQSEVTYFIKDP
PSKAVIQPNQAVTLVTSDGFTTSVGIARKNVTATRNTNNNANTKQESVSL
LEHQSVKRELESYKVQIQALQSQLEEQTRLYKEQTDALMEDRTIRQQETE
AQRSRDQEKIQALSDKLKRTQELLYDNTKDFLSQRSQYRENEKQWISEKD
LMFRKLKTKESSAGQSGTGNKWIHVDPTSLQSKAFSEWTGQMKDQKEEQY
KNTINNLDYQLEQQQKLAEMYREQVIEMENELAQIREEGDATKDIYKTRS
TKINDRLQIMNQRYKDLERRRNLEVQGFQTDIGNLRKKLKNLEKQLYMVT
MSLGDQISSSGPNLMPQNLDLAILREVKHTAARSNHLSGQLKDLKAMMYG
LERELRQL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR037696CCDC77
Vocabulary: cellular component
TermDefinition
GO:0005813centrosome
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 203..237
NoneNo IPR availableCOILSCoilCoilcoord: 425..445
NoneNo IPR availableCOILSCoilCoilcoord: 42..69
NoneNo IPR availableCOILSCoilCoilcoord: 347..388
NoneNo IPR availableCOILSCoilCoilcoord: 400..420
NoneNo IPR availableCOILSCoilCoilcoord: 246..273
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..25
IPR037696Coiled-coil domain-containing protein 77PANTHERPTHR22091UNCHARACTERIZEDcoord: 29..507