Bidirectional sugar transporter SWEET

Overview
NameBidirectional sugar transporter SWEET
Smed IDSMED30022225
Length (bp)769
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Bidirectional sugar transporter SWEET (SMED30022225) t-SNE clustered cells

Violin plots show distribution of expression levels for Bidirectional sugar transporter SWEET (SMED30022225) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Bidirectional sugar transporter SWEET (SMED30022225) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Bidirectional sugar transporter SWEET (SMED30022225) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30022225

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30022225h1SMcG0001119 dd_Smed_v4_12308_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Human
Match: SLC50A1 (solute carrier family 50 member 1 [Source:HGNC Symbol;Acc:HGNC:30657])

HSP 1 Score: 48.521 bits (114), Expect = 2.511e-6
Identity = 41/157 (26.11%), Postives = 72/157 (45.86%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLI--YPTLIGSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLG 636
            S D+  F P+     +++ WL Y  L  D  LI  N   A +    IL +  Y   K  ++    TL+G  L+  G F+ +    E+++  L ++C + ++  + +PL+ +  V + KS   +S+ L  +  L    W  YG    D  +M+ N  G
Sbjct:   38 SVDNVQFLPFLTTEVNNLGWLSYGALKGDGILIVVNTVGAALQTLYILAYLHYCPRKRVVLLQTATLLGVLLLGYGYFWLLVPNPEARLQQLGLFCSVFTISMYLSPLADLAKVIQTKSTQCLSYPLTIATLLTSASWCLYGFRLRDPYIMVSNFPG 194
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Celegans
Match: swt-1 (Sugar transporter SWEET1 [Source:UniProtKB/Swiss-Prot;Acc:O45102])

HSP 1 Score: 77.411 bits (189), Expect = 1.811e-16
Identity = 50/167 (29.94%), Postives = 85/167 (50.90%), Query Frame = 1 
Query:  229 WLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFN-----LIYPTLIGSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIPFVAKLSLKNEK 714
            WL+Y  L  D  +I  N+       F  +FF +YS  K       ++  + IG  ++ I L  N++        +L V C   ++M FGAPL+ +  V +N+ ++ +   +C +NFL+   W  YG L  D  ++I N +G  L+I QL+L++++P       +NEK
Sbjct:   55 WLRYGLLKMDYVMIIVNVVGVACMAFYCVFFLIYSLPKKTFTCQLILVTSTIGGMVLWIALKPNLD--------YLGVICMTFNIMNFGAPLAGLGVVLKNREVSTLPLPMCVANFLVSSQWCLYGNLVSDIYIIIPNGIGMFLAIVQLALFVVLPI-----RENEK 208
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Celegans
Match: swt-2 (Sugar transporter SWEET [Source:UniProtKB/TrEMBL;Acc:A0A2C9C3B1])

HSP 1 Score: 74.3294 bits (181), Expect = 1.201e-15
Identity = 59/202 (29.21%), Postives = 105/202 (51.98%), Query Frame = 1 
Query:   79 ITEFVGVAATAFSLLQNCXXXXXXXXXXXXXSSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQ-MKFNLIYPTLIGSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            I  FV + A  F+++Q    + I  +I  +G     S FP+         WL+Y FL  D+ LI  N     I+ F  +FF  +S+  K+ +   +++   ++T+ +  + N  V+    FL   C +++++ FG+PL+ +  V R++ +  + F LC    ++  LW  YG+L  D+ L+I   +G  +S+ QLSL+LI P
Sbjct:    5 IIYFVSIVAFVFTIIQFFTGIPICLQIYRQGHVGDISGFPFLMGTLVLPFWLRYGFLRNDVMLISINCAGIPIAVFNAMFFLYFSKPKKYYMTQLSIVTIIILTMLMLIHFNPNVQ----FLGFVCIVLNLITFGSPLAGLRVVLRDREVITLPFVLCLVQLIVQCLWNLYGILIQDFFLVIPTAVGIMISLVQLSLFLIFP 202
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Celegans
Match: swt-2 (Sugar transporter SWEET [Source:UniProtKB/TrEMBL;Acc:A0A2C9C3B1])

HSP 1 Score: 73.1738 bits (178), Expect = 1.642e-15
Identity = 47/152 (30.92%), Postives = 85/152 (55.92%), Query Frame = 1 
Query:  229 WLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQ-MKFNLIYPTLIGSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            WL+Y FL  D+ LI  N     I+ F  +FF  +S+  K+ +   +++   ++T+ +  + N  V+    FL   C +++++ FG+PL+ +  V R++ +  + F LC    ++  LW  YG+L  D+ L+I   +G  +S+ QLSL+LI P
Sbjct:    9 WLRYGFLRNDVMLISINCAGIPIAVFNAMFFLYFSKPKKYYMTQLSIVTIIILTMLMLIHFNPNVQ----FLGFVCIVLNLITFGSPLAGLRVVLRDREVITLPFVLCLVQLIVQCLWNLYGILIQDFFLVIPTAVGIMISLVQLSLFLIFP 156
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Celegans
Match: swt-4 (Sugar transporter SWEET [Source:UniProtKB/TrEMBL;Acc:Q9XX26])

HSP 1 Score: 67.0106 bits (162), Expect = 3.866e-13
Identity = 45/172 (26.16%), Postives = 90/172 (52.33%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISG-FIILFFYLYSQMKF-NLIYPTLIGSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            SS+  S  P+  +F S   +++Y  L  D  + + N     +   +++ F+Y+    +F N +    +G   I +    +  ++  ++ +++  YC  +++ +  APL  I  V RNKS   +   LC + F++ + W+ YG + DD  +++ N++ T +SI QLSL++I P
Sbjct:   40 SSEGTSPAPFLLSFLSCGLFIQYGLLKDDDVITYCNGIGCFLQACYLMYFYYMTRNRRFLNKVISIELGIIGIVVYWVAHSTNSHLTKTTYVGNYCIFLNICSVAAPLFDIGKVVRNKSSESLPLPLCVACFVVCLQWMFYGYIVDDIVILVPNVIATVISILQLSLFIIYP 211
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Celegans
Match: swt-4 (Sugar transporter SWEET [Source:UniProtKB/TrEMBL;Acc:Q9XX26])

HSP 1 Score: 67.3958 bits (163), Expect = 4.136e-13
Identity = 45/172 (26.16%), Postives = 90/172 (52.33%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISG-FIILFFYLYSQMKF-NLIYPTLIGSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            SS+  S  P+  +F S   +++Y  L  D  + + N     +   +++ F+Y+    +F N +    +G   I +    +  ++  ++ +++  YC  +++ +  APL  I  V RNKS   +   LC + F++ + W+ YG + DD  +++ N++ T +SI QLSL++I P
Sbjct:   58 SSEGTSPAPFLLSFLSCGLFIQYGLLKDDDVITYCNGIGCFLQACYLMYFYYMTRNRRFLNKVISIELGIIGIVVYWVAHSTNSHLTKTTYVGNYCIFLNICSVAAPLFDIGKVVRNKSSESLPLPLCVACFVVCLQWMFYGYIVDDIVILVPNVIATVISILQLSLFIIYP 229
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Fly
Match: slv (gene:FBgn0025469 transcript:FBtr0088824)

HSP 1 Score: 58.9214 bits (141), Expect = 4.058e-10
Identity = 42/172 (24.42%), Postives = 83/172 (48.26%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLFF--NVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            S+   S  P+   F S   WL+Y  L  +  ++  NI  + +     L +Y+++  K   +        ++ + + +   + D  +  I    + C +++V  F APL+++  V R K+   +   L  ++F++ + W+ YG+L  D  + I N LG  LS+ QL L+++ P
Sbjct:   37 STGDSSGVPFICGFLSCSFWLRYGVLTNEQSIVLVNIIGSTLFLVYTLIYYVFTVNKRACVKQFGFVLTVLVVVIVYTNRLEDQRDRMIHVTGIVCCIVTVCFFAAPLASLLHVIRAKNSESLPLPLIATSFVVSLQWLIYGILISDSFIQIPNFLGCILSLLQLGLFVLYP 208
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Fly
Match: slv (gene:FBgn0025469 transcript:FBtr0310369)

HSP 1 Score: 58.9214 bits (141), Expect = 4.058e-10
Identity = 42/172 (24.42%), Postives = 83/172 (48.26%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLFF--NVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            S+   S  P+   F S   WL+Y  L  +  ++  NI  + +     L +Y+++  K   +        ++ + + +   + D  +  I    + C +++V  F APL+++  V R K+   +   L  ++F++ + W+ YG+L  D  + I N LG  LS+ QL L+++ P
Sbjct:   37 STGDSSGVPFICGFLSCSFWLRYGVLTNEQSIVLVNIIGSTLFLVYTLIYYVFTVNKRACVKQFGFVLTVLVVVIVYTNRLEDQRDRMIHVTGIVCCIVTVCFFAAPLASLLHVIRAKNSESLPLPLIATSFVVSLQWLIYGILISDSFIQIPNFLGCILSLLQLGLFVLYP 208
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Fly
Match: slv (gene:FBgn0025469 transcript:FBtr0339280)

HSP 1 Score: 58.9214 bits (141), Expect = 4.058e-10
Identity = 42/172 (24.42%), Postives = 83/172 (48.26%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLFF--NVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            S+   S  P+   F S   WL+Y  L  +  ++  NI  + +     L +Y+++  K   +        ++ + + +   + D  +  I    + C +++V  F APL+++  V R K+   +   L  ++F++ + W+ YG+L  D  + I N LG  LS+ QL L+++ P
Sbjct:   37 STGDSSGVPFICGFLSCSFWLRYGVLTNEQSIVLVNIIGSTLFLVYTLIYYVFTVNKRACVKQFGFVLTVLVVVIVYTNRLEDQRDRMIHVTGIVCCIVTVCFFAAPLASLLHVIRAKNSESLPLPLIATSFVVSLQWLIYGILISDSFIQIPNFLGCILSLLQLGLFVLYP 208
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Zebrafish
Match: slc50a1 (solute carrier family 50 member 1 [Source:NCBI gene;Acc:503533])

HSP 1 Score: 69.3218 bits (168), Expect = 8.799e-14
Identity = 46/157 (29.30%), Postives = 80/157 (50.96%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIG-SFLITIGLFFN-VNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLG 636
            S+D+  F P+     +++ WL Y  L  D  +IF NI  A +    I  +  Y++ K  +   TL+  S L    ++F+ V    E+Q+S L + C + ++  + +PL+ +  + R KS+ ++SFSL  + F     W  YG+   DY +M+ N  G
Sbjct:   34 SADNVQFLPFLTTCLNNLGWLYYGLLKGDGTVIFVNIIGAFLQTVYIATYCHYTKEKRRVYTQTLLMVSVLCVAWVYFSLVISPGEAQLSQLGLTCSVFTISMYLSPLADLLDIMRTKSVERLSFSLTVATFFTSTSWTLYGLQLGDYYIMVPNTPG 190
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Xenopus
Match: slc50a1 (solute carrier family 50 (sugar efflux transporter), member 1 [Source:NCBI gene;Acc:548582])

HSP 1 Score: 55.4546 bits (132), Expect = 1.077e-8
Identity = 39/178 (21.91%), Postives = 85/178 (47.75%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYS-QMKFNLIYPTLIGSFLITIGLFFNVN-------DAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            S ++  F P+     +++ W  Y +L  D  LI  N+  A +    +  + LYS + ++      ++   L+++G+ F  +         + S+++ L ++C + ++  + +PL+ +  + ++KS   +SF L  + FL    WV YG ++ D  + + N  G   S+ +  L+   P
Sbjct:   32 SVENIQFLPFLTTDLNNLGWFYYGYLKGDGTLIIVNLIGASLQTLYMAAYILYSLERRY------VVSQVLVSLGVLFLAHCYFTLWTPDINSRLNQLGLFCSIFTISMYLSPLADLAQIIKSKSTKCLSFPLTVATFLTSTSWVLYGWVQSDLYITVPNFPGIVTSLLRFWLFSRYP 203
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Xenopus
Match: slc50a1 (solute carrier family 50 (sugar efflux transporter), member 1 [Source:NCBI gene;Acc:548582])

HSP 1 Score: 53.5286 bits (127), Expect = 8.092e-8
Identity = 35/159 (22.01%), Postives = 78/159 (49.06%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYS-QMKFNLIYPTLIGSFLITIGLFFNVN-------DAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMIC 624
            S ++  F P+     +++ W  Y +L  D  LI  N+  A +    +  + LYS + ++      ++   L+++G+ F  +         + S+++ L ++C + ++  + +PL+ +  + ++KS   +SF L  + FL    WV YG ++ D  + +C
Sbjct:   99 SVENIQFLPFLTTDLNNLGWFYYGYLKGDGTLIIVNLIGASLQTLYMAAYILYSLERRY------VVSQVLVSLGVLFLAHCYFTLWTPDINSRLNQLGLFCSIFTISMYLSPLADLAQIIKSKSTKCLSFPLTVATFLTSTSWVLYGWVQSDLYITVC 251
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Xenopus
Match: slc50a1 (solute carrier family 50 (sugar efflux transporter), member 1 [Source:NCBI gene;Acc:548582])

HSP 1 Score: 52.7582 bits (125), Expect = 1.368e-7
Identity = 36/162 (22.22%), Postives = 77/162 (47.53%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLFFNVN-------DAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLG 636
            S ++  F P+     +++ W  Y +L  D  LI  N+  A +    +  + LYS  +  ++        L+++G+ F  +         + S+++ L ++C + ++  + +PL+ +  + ++KS   +SF L  + FL    WV YG ++ D  + + N  G
Sbjct:   99 SVENIQFLPFLTTDLNNLGWFYYGYLKGDGTLIIVNLIGASLQTLYMAAYILYSLERRYVV-----SQVLVSLGVLFLAHCYFTLWTPDINSRLNQLGLFCSIFTISMYLSPLADLAQIIKSKSTKCLSFPLTVATFLTSTSWVLYGWVQSDLYITVPNFPG 255
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Mouse
Match: Slc50a1 (solute carrier family 50 (sugar transporter), member 1 [Source:MGI Symbol;Acc:MGI:107417])

HSP 1 Score: 61.6178 bits (148), Expect = 5.879e-11
Identity = 46/173 (26.59%), Postives = 84/173 (48.55%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGL--FFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYG-MLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            S D+  F P+     +++ WL Y  L  D  LI  N   AV+    IL +  YS  K  ++  T     ++ +G   F+ +   +E+++  L ++C + ++  + +PL+ +  + + KS  ++SFSL  +       W  YG  L+D Y + + NL G   S+ +L L+   P
Sbjct:   38 SVDNIQFLPFLTTDVNNLSWLSYGVLKGDGTLIIVNSVGAVLQTLYILAYLHYSPQKHGVLLQTATLLAVLLLGYGYFWLLVPDLEARLQQLGLFCSVFTISMYLSPLADLAKIVQTKSTQRLSFSLTIATLFCSASWSIYGFRLRDPY-ITVPNLPGILTSLIRLGLFCKYP 209
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. UniProt/SwissProt
Match: sp|O45102|SWET1_CAEEL (Sugar transporter SWEET1 OS=Caenorhabditis elegans OX=6239 GN=swt-1 PE=3 SV=1)

HSP 1 Score: 77.411 bits (189), Expect = 2.304e-15
Identity = 50/167 (29.94%), Postives = 85/167 (50.90%), Query Frame = 1 
Query:  229 WLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFN-----LIYPTLIGSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIPFVAKLSLKNEK 714
            WL+Y  L  D  +I  N+       F  +FF +YS  K       ++  + IG  ++ I L  N++        +L V C   ++M FGAPL+ +  V +N+ ++ +   +C +NFL+   W  YG L  D  ++I N +G  L+I QL+L++++P       +NEK
Sbjct:   55 WLRYGLLKMDYVMIIVNVVGVACMAFYCVFFLIYSLPKKTFTCQLILVTSTIGGMVLWIALKPNLD--------YLGVICMTFNIMNFGAPLAGLGVVLKNREVSTLPLPMCVANFLVSSQWCLYGNLVSDIYIIIPNGIGMFLAIVQLALFVVLPI-----RENEK 208
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. UniProt/SwissProt
Match: sp|A8XI14|SWET1_CAEBR (Sugar transporter SWEET1 OS=Caenorhabditis briggsae OX=6238 GN=swt-1 PE=3 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 4.450e-15
Identity = 49/162 (30.25%), Postives = 83/162 (51.23%), Query Frame = 1 
Query:  229 WLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIPFVAKLSLKNEK 714
            WL+Y  L  D  +I  N+          +FF +YS  K       ++ +  IT G+   +  A +  + +L + C   ++M FGAPL+ +  V RN+ ++ +   +C +NFL+   W  YG L  D  ++I N +G  L+I QLSL++++P       +NEK
Sbjct:   55 WLRYGLLKMDYTMIIVNVVGVFCMAVYCIFFLIYSLPKKTFTCQLILVTSTIT-GMVVWI--AFKPNLDYLGIICMTFNIMNFGAPLAGLGVVLRNREVSTLPLPMCVANFLVSSQWCLYGNLVQDIYIIIPNGIGMFLAIVQLSLFIVLP-----RRENEK 208
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. UniProt/SwissProt
Match: sp|P0DKJ5|SWT15_VITVI (Bidirectional sugar transporter SWEET15 OS=Vitis vinifera OX=29760 GN=SWEET15 PE=3 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 1.620e-14
Identity = 59/173 (34.10%), Postives = 87/173 (50.29%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFS-NIFSAVISGFIILFFYLYSQMK-----FNLIYPTLIGSFLITIGLF-FNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLY 669
            S++ F   PY     S++ WL YA L  D  L+ + N F   I  F IL ++ Y+ M+       ++    +G F I + L  F +  +  ++I+     C   SV  F APLS +  V R KS+  M FSL F   L  I+W  YG+LK+D  + I N+LG  L + Q+ LY
Sbjct:   42 SAEGFHSLPYIVALFSAMLWLYYALLKKDAFLLITINSFGCAIESFYILLYFFYAPMQAKKQTLKVVISLNVGVFSILVVLIQFLLKGS--NRINVFGWICASFSVAVFAAPLSIVAKVIRTKSVEFMPFSLSFFLTLSAIMWFAYGLLKNDPCVAIPNILGVILGLVQMVLY 212
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. UniProt/SwissProt
Match: sp|Q5EB14|SWET1_DANRE (Sugar transporter SWEET1 OS=Danio rerio OX=7955 GN=slc50a1 PE=2 SV=2)

HSP 1 Score: 69.3218 bits (168), Expect = 6.642e-13
Identity = 46/157 (29.30%), Postives = 80/157 (50.96%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIG-SFLITIGLFFN-VNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLG 636
            S+D+  F P+     +++ WL Y  L  D  +IF NI  A +    I  +  Y++ K  +   TL+  S L    ++F+ V    E+Q+S L + C + ++  + +PL+ +  + R KS+ ++SFSL  + F     W  YG+   DY +M+ N  G
Sbjct:   34 SADNVQFLPFLTTCLNNLGWLYYGLLKGDGTVIFVNIIGAFLQTVYIATYCHYTKEKRRVYTQTLLMVSVLCVAWVYFSLVISPGEAQLSQLGLTCSVFTISMYLSPLADLLDIMRTKSVERLSFSLTVATFFTSTSWTLYGLQLGDYYIMVPNTPG 190
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. UniProt/SwissProt
Match: sp|B8BKP4|SWT14_ORYSI (Bidirectional sugar transporter SWEET14 OS=Oryza sativa subsp. indica OX=39946 GN=SWEET14 PE=2 SV=1)

HSP 1 Score: 66.2402 bits (160), Expect = 1.984e-11
Identity = 54/173 (31.21%), Postives = 81/173 (46.82%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFS-NIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLF------FNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLY 669
            S+  F   PY     S++ W+ YA L  D  L+ + N    VI    I  + +Y+  K  +    L+   L+ +G+F        +  A + +I  L   C   SV  F APLS I  V R KS+  M FSL FS  +  ++W  YG+L  D  + + N+LG    + Q+ LY
Sbjct:   41 STQGFQSVPYVVALFSAMLWIYYALLKSDECLLITINSAGCVIETIYIAVYLVYAPKKAKMFTAKLL--LLVNVGVFGLILLLTLLLSAGDRRIVVLGWVCVGFSVSVFVAPLSIIRLVVRTKSVEFMPFSLSFSLTISAVVWFLYGLLIKDKYVALPNVLGFSFGVIQMGLY 211
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. TrEMBL
Match: A0A267FU21 (Sugar transporter SWEET (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010422g1 PE=3 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 6.502e-25
Identity = 73/200 (36.50%), Postives = 109/200 (54.50%), Query Frame = 1 
Query:   85 EFVGVAATAFSLLQNCXXXXXXXXXXXXXSSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLI-TIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
              VG  A+ FS+L     L I+R I    SS+ +S FPY A  ASS  WLKY  +  D PLI  + FS  I   I+  FYL+++ +  + +  L+   ++  +  +   +  ++  I  L VYC  +S++++G+PLSA++ V R KS   MS SL   NF+   LW+TYG L  D +L + N +G  LS  QL L  + P
Sbjct:   13 HLVGNLASIFSILSYLPGLKIMRDIILSKSSESYSLFPYVAMLASSSVWLKYGLVREDFPLITVSCFSLSIQTTILFVFYLFARHRGAIHFQLLLCMLMVFPVLSYVRYSPNLDLAIEHLGVYCTAVSIVSYGSPLSAMSEVLRTKSSESMSLSLIMLNFITACLWLTYGTLVHDSNLTVPNFVGACLSCFQLGLICVFP 212
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. TrEMBL
Match: A0A267G506 (Sugar transporter SWEET (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030993g3 PE=3 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 1.986e-24
Identity = 72/200 (36.00%), Postives = 108/200 (54.00%), Query Frame = 1 
Query:   85 EFVGVAATAFSLLQNCXXXXXXXXXXXXXSSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLI-TIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
              VG  A+ FS+      L I+R I    SS+ +S FPY A  ASS  WLKY  +  D PLI  + FS  I   I+  FYL+++ +  + +  L+   ++  +  +   +  ++  I  L VYC  +S++++G+PLSA++ V R KS   MS SL   NF+   LW+TYG L  D +L + N +G  LS  QL L  + P
Sbjct:   13 HLVGNLASIFSIFSYLPGLKIMRDIILSKSSESYSLFPYVAMLASSSVWLKYGLVREDFPLITVSCFSLSIQTTIVFVFYLFARHRGAIHFQLLLCMLMVFPVLSYVRYSPNLDLAIEHLGVYCTAVSIVSYGSPLSAMSEVLRTKSSESMSLSLIMLNFITACLWLTYGTLVHDSNLTVPNFVGACLSCFQLGLICVFP 212
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. TrEMBL
Match: A0A267FIE0 (Sugar transporter SWEET (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030993g1 PE=3 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 2.022e-24
Identity = 72/200 (36.00%), Postives = 108/200 (54.00%), Query Frame = 1 
Query:   85 EFVGVAATAFSLLQNCXXXXXXXXXXXXXSSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLI-TIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
              VG  A+ FS+L     L I+R I    SS+ +S FPY A  ASS  WLKY  +  D PLI  + FS  I   I+  FYL+++ +  + +  L+   ++  +  +   +  ++  I  L VYC  +S++++G+PLSA++ V R KS   MS SL   NF+   LW+TYG L  D +L + N +G  LS  QL    + P
Sbjct:   11 HLVGNLASIFSILSYLPGLKIMRDIILSKSSESYSLFPYVAMLASSSVWLKYGLVREDFPLITVSCFSLSIQTTIVFVFYLFARHRGAIHFQLLLCMLMVFPVLSYVRYSPNLDLAIEHLGVYCTAVSIVSYGSPLSAMSEVLRTKSSESMSLSLIMLNFITACLWLTYGTLVHDSNLTVPNFVGACLSCFQLGFICVFP 210
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. TrEMBL
Match: R7TA68 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_101387 PE=3 SV=1)

HSP 1 Score: 93.9745 bits (232), Expect = 1.420e-19
Identity = 59/176 (33.52%), Postives = 96/176 (54.55%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLFF------NVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            S+   SFFP    F ++  W+KYA +  D  L+++N   +V++   +  +YLY+  K ++      G+FL+   L +      N++DAV     +L   C  + VM +GAPLSA++ V R KS   M+F L  +NF++ I W +YG L  D+ + + NL+G  L   QL+L+   P
Sbjct:   34 STQDTSFFPLIVMFCNTTLWVKYALIKDDPTLLYANSVGSVLTFIYVSIYYLYTTHKTHVHRNLAFGAFLLFPILIYVKFYADNLDDAVL----YLGFVCSSVGVMGYGAPLSAMSEVLRTKSTECMAFPLSLANFIVAIEWFSYGFLLRDFYIQVPNLIGIFLGGLQLALFWKYP 205
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. TrEMBL
Match: A7SFC4 (Sugar transporter SWEET OS=Nematostella vectensis OX=45351 GN=v1g244871 PE=3 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 1.074e-18
Identity = 59/174 (33.91%), Postives = 90/174 (51.72%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLF----FNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            S+   +  P+ A  ASSI W KY  L  D P+   +    +     +L FYL S+ K  L  P L  SF +  G+     ++V D  E+ +  L + C + SV  +G+PL ++ +V R KS   ++FSLC +NFL+ + W  YG L  D  + + N +G  L   QLSL++  P
Sbjct:   34 STGDVAVLPFLATCASSILWTKYGLLTKDFPITVISAAGIIFQSLYLLIFYLNSRDKKTL-NPKLFWSFCLVCGVLSYIKYHVMDK-ETAVFHLGLVCSVFSVAVYGSPLVSLATVIRKKSTECLTFSLCLANFLVSLQWAMYGKLAQDNFITVPNSVGALLGSLQLSLFVCYP 205
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Cavefish
Match: slc50a1 (solute carrier family 50 member 1 [Source:NCBI gene;Acc:503533])

HSP 1 Score: 63.1586 bits (152), Expect = 1.375e-11
Identity = 43/157 (27.39%), Postives = 79/157 (50.32%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIG-LFFNVN-DAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLG 636
            S+D   F P+     +++ WL Y  L  D  L+  N+  A +    I+ ++ Y++ K  +   TL  + ++ +  ++F V     E+Q+S L ++C + +V  + +PL  I    R +S+ ++SFSL  + F     W  YG+   DY +M+ N  G
Sbjct:   34 SADSVQFLPFLTTCLNNLGWLYYGILKKDGTLMVVNVIGASLQILYIVTYFHYTKDKRRVSAQTLAMAGVLGVAWVYFGVMLPHGETQLSQLGLFCSVFTVSMYLSPLLEII---RTRSVERLSFSLTVATFFTSASWTLYGLQLQDYYIMVPNTPG 187
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006024.1 (pep scaffold:Pmarinus_7.0:GL478690:52525:56557:1 gene:ENSPMAG00000005445.1 transcript:ENSPMAT00000006024.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.5514 bits (166), Expect = 1.628e-14
Identity = 42/155 (27.10%), Postives = 78/155 (50.32%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLFFNVNDAVESQIS---FLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICN 627
            S+   S FP+ +       WL+Y  L+ D  +++ N   A I     + FY+ +  K +L Y T++G  L+   +   V    E + +    L + C L +V+ +G+PL+ +  V R++S   ++F LC +N ++G  W  YG++  D  + + N
Sbjct:   15 STIGLSMFPFVSLCVRCTLWLRYGLLLGDPTIVYVNAVGASIGVLFSIIFYVNTPHKRSL-YRTMVGPALLLYSVLLYVKYLAEDEDAARPHLGMVCTLWTVVNYGSPLATLAEVVRSRSTESLAFPLCAANLVVGTEWFIYGLMLQDTFIQVPN 168
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006019.1 (pep scaffold:Pmarinus_7.0:GL478690:52525:56575:1 gene:ENSPMAG00000005445.1 transcript:ENSPMAT00000006019.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.781 bits (164), Expect = 4.107e-14
Identity = 43/155 (27.74%), Postives = 81/155 (52.26%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLFFNVNDAVESQIS---FLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICN 627
            S+   S FP+ +   S++ WL+Y  L+ D  +++ N   A I     + FY+ +  K +L Y T++G  L+   +   V    E + +    L + C L +V+ +G+PL+ +  V R++S   ++F LC +N ++G  W  YG++  D  + + N
Sbjct:   15 STIGLSMFPFVSLCVSTL-WLRYGLLLGDPTIVYVNAVGASIGVLFSIIFYVNTPHKRSL-YRTMVGPALLLYSVLLYVKYLAEDEDAARPHLGMVCTLWTVVNYGSPLATLAEVVRSRSTESLAFPLCAANLVVGTEWFIYGLMLQDTFIQVPN 167
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Nematostella
Match: EDO37599 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFC4])

HSP 1 Score: 92.0485 bits (227), Expect = 1.485e-22
Identity = 59/174 (33.91%), Postives = 90/174 (51.72%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLIGSFLITIGLF----FNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIP 681
            S+   +  P+ A  ASSI W KY  L  D P+   +    +     +L FYL S+ K  L  P L  SF +  G+     ++V D  E+ +  L + C + SV  +G+PL ++ +V R KS   ++FSLC +NFL+ + W  YG L  D  + + N +G  L   QLSL++  P
Sbjct:   34 STGDVAVLPFLATCASSILWTKYGLLTKDFPITVISAAGIIFQSLYLLIFYLNSRDKKTL-NPKLFWSFCLVCGVLSYIKYHVMDK-ETAVFHLGLVCSVFSVAVYGSPLVSLATVIRKKSTECLTFSLCLANFLVSLQWAMYGKLAQDNFITVPNSVGALLGSLQLSLFVCYP 205
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Nematostella
Match: EDO30941 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZC5])

HSP 1 Score: 56.9954 bits (136), Expect = 6.827e-10
Identity = 44/166 (26.51%), Postives = 81/166 (48.80%), Query Frame = 1 
Query:  187 SFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFN---LIYPTLIGSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLI 675
             F P+     + + W  Y +L  D  +I  N   A++    IL F  +S+ + N    ++ + I S  + + L F + ++  +++S +   C ++++M   +PL+ +  V R KS   M F+  F   L   +W+ YG +  D ++ + NL G  L   QLSL+ I
Sbjct:   38 QFLPFVTTLMNCLLWTIYGYLKDDSTIIIVNFVGALLQVVYILCFLYFSRERGNNLAFLFYSAIASASLFMYLSFVIVES-NTRLSHMGKICIVVTIMMQASPLATVARVIRTKSTESMQFTFSFLITLCSFVWLCYGTVIYDINVQLPNLSGVLLGFSQLSLFCI 202
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Medaka
Match: slc50a1 (solute carrier family 50 member 1 [Source:NCBI gene;Acc:101175505])

HSP 1 Score: 68.9366 bits (167), Expect = 1.186e-13
Identity = 45/168 (26.79%), Postives = 88/168 (52.38%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLI-GSFLITIGLFFNV-NDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLY 669
            S+++  F P+     +++ WL Y  L  D  ++F N   A++    I+ ++ Y++MK  +   TL  G  LIT  L+F       E++++ L + C +++V  + +PL  +  + R++++  +SF L  + F     WV YG+  +DY +M+ N  G   S+ +  L+
Sbjct:   34 SAENIQFLPFLTTCLNNLGWLFYGILKKDHTIVFVNTIGALLQILYIVMYFYYTKMKRQVTLQTLAAGVTLITGWLYFTTFLTEGEARLNQLGLTCSVVTVSMYLSPLFDLVEIVRSRNVQCLSFPLTVATFFTSTSWVLYGLQLNDYYIMVPNTPGIFTSLIRFYLF 201
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Medaka
Match: slc50a1 (solute carrier family 50 member 1 [Source:NCBI gene;Acc:101175505])

HSP 1 Score: 68.9366 bits (167), Expect = 1.320e-13
Identity = 45/168 (26.79%), Postives = 88/168 (52.38%), Query Frame = 1 
Query:  172 SSDHFSFFPYCANFASSICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLI-GSFLITIGLFFNV-NDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLY 669
            S+++  F P+     +++ WL Y  L  D  ++F N   A++    I+ ++ Y++MK  +   TL  G  LIT  L+F       E++++ L + C +++V  + +PL  +  + R++++  +SF L  + F     WV YG+  +DY +M+ N  G   S+ +  L+
Sbjct:   34 SAENIQFLPFLTTCLNNLGWLFYGILKKDHTIVFVNTIGALLQILYIVMYFYYTKMKRQVTLQTLAAGVTLITGWLYFTTFLTEGEARLNQLGLTCSVVTVSMYLSPLFDLVEIVRSRNVQCLSFPLTVATFFTSTSWVLYGLQLNDYYIMVPNTPGIFTSLIRFYLF 201
[Close]
BLAST of Bidirectional sugar transporter SWEET vs. Planmine SMEST
Match: SMESG000012540.1 (SMESG000012540.1)

HSP 1 Score: 245.358 bits (625), Expect = 2.678e-83
Identity = 123/126 (97.62%), Postives = 125/126 (99.21%), Query Frame = 1 
Query:  337 MKFNLIYPTLIGSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIPFVAKLSLKNEK 714
            MKFNLIYPTLIGSFLITIGLFFNVN+ VESQISFLQVYCPLMSVMAFGAPLSAITSVWR+KSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIPFVAKLSLKNEK
Sbjct:    1 MKFNLIYPTLIGSFLITIGLFFNVNNVVESQISFLQVYCPLMSVMAFGAPLSAITSVWRSKSLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLYLIIPFVAKLSLKNEK 126
The following BLAST results are available for this feature:
BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
SLC50A12.511e-626.11solute carrier family 50 member 1 [Source:HGNC Sym... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
swt-11.811e-1629.94Sugar transporter SWEET1 [Source:UniProtKB/Swiss-... [more]
swt-21.201e-1529.21Sugar transporter SWEET [Source:UniProtKB/TrEMBL;... [more]
swt-21.642e-1530.92Sugar transporter SWEET [Source:UniProtKB/TrEMBL;... [more]
swt-43.866e-1326.16Sugar transporter SWEET [Source:UniProtKB/TrEMBL;... [more]
swt-44.136e-1326.16Sugar transporter SWEET [Source:UniProtKB/TrEMBL;... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
slv4.058e-1024.42gene:FBgn0025469 transcript:FBtr0088824[more]
slv4.058e-1024.42gene:FBgn0025469 transcript:FBtr0310369[more]
slv4.058e-1024.42gene:FBgn0025469 transcript:FBtr0339280[more]
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BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
slc50a18.799e-1429.30solute carrier family 50 member 1 [Source:NCBI gen... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
slc50a11.077e-821.91solute carrier family 50 (sugar efflux transporter... [more]
slc50a18.092e-822.01solute carrier family 50 (sugar efflux transporter... [more]
slc50a11.368e-722.22solute carrier family 50 (sugar efflux transporter... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Slc50a15.879e-1126.59solute carrier family 50 (sugar transporter), memb... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O45102|SWET1_CAEEL2.304e-1529.94Sugar transporter SWEET1 OS=Caenorhabditis elegans... [more]
sp|A8XI14|SWET1_CAEBR4.450e-1530.25Sugar transporter SWEET1 OS=Caenorhabditis briggsa... [more]
sp|P0DKJ5|SWT15_VITVI1.620e-1434.10Bidirectional sugar transporter SWEET15 OS=Vitis v... [more]
sp|Q5EB14|SWET1_DANRE6.642e-1329.30Sugar transporter SWEET1 OS=Danio rerio OX=7955 GN... [more]
sp|B8BKP4|SWT14_ORYSI1.984e-1131.21Bidirectional sugar transporter SWEET14 OS=Oryza s... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267FU216.502e-2536.50Sugar transporter SWEET (Fragment) OS=Macrostomum ... [more]
A0A267G5061.986e-2436.00Sugar transporter SWEET (Fragment) OS=Macrostomum ... [more]
A0A267FIE02.022e-2436.00Sugar transporter SWEET (Fragment) OS=Macrostomum ... [more]
R7TA681.420e-1933.52Uncharacterized protein OS=Capitella teleta OX=283... [more]
A7SFC41.074e-1833.91Sugar transporter SWEET OS=Nematostella vectensis ... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
slc50a11.375e-1127.39solute carrier family 50 member 1 [Source:NCBI gen... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000006024.11.628e-1427.10pep scaffold:Pmarinus_7.0:GL478690:52525:56557:1 g... [more]
ENSPMAT00000006019.14.107e-1427.74pep scaffold:Pmarinus_7.0:GL478690:52525:56575:1 g... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO375991.485e-2233.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO309416.827e-1026.51Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
slc50a11.186e-1326.79solute carrier family 50 member 1 [Source:NCBI gen... [more]
slc50a11.320e-1326.79solute carrier family 50 member 1 [Source:NCBI gen... [more]
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BLAST of Bidirectional sugar transporter SWEET vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000012540.12.678e-8397.62SMESG000012540.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022225 ID=SMED30022225|Name=Bidirectional sugar transporter SWEET|organism=Schmidtea mediterranea sexual|type=transcript|length=769bp
AGGATTTTTAATACTTTTAGTTGCAATCAGATTTATTTCTTGTGTGTTTT
TATATTTTAATTCTACAAGATGTTATCAATAACAGAATTTGTCGGAGTAG
CTGCGACTGCATTTTCTTTGCTTCAGAACTGTATTATATTGTTGATTGTT
AGGCGCATCAGAGGCAGAGGTTCATCAGATCATTTTTCATTCTTTCCATA
TTGTGCAAATTTTGCGTCATCTATTTGTTGGTTGAAATATGCGTTCCTAA
TTTTTGATATGCCACTTATTTTTTCTAATATTTTTTCTGCAGTTATCAGT
GGATTTATTATTTTATTTTTTTATCTATACTCACAAATGAAATTTAATCT
TATTTATCCGACTCTTATTGGATCGTTTTTAATTACTATCGGATTATTTT
TCAACGTTAATGACGCTGTGGAATCCCAAATCAGCTTTCTACAAGTTTAT
TGTCCATTAATGAGTGTAATGGCTTTCGGAGCCCCTCTTTCAGCCATTAC
CAGTGTTTGGAGGAATAAATCACTGAATCAGATGTCATTTTCTTTATGTT
TCTCAAACTTCCTTATTGGTATCCTCTGGGTGACCTACGGAATGCTGAAA
GATGATTATTCTTTGATGATTTGCAATTTGTTGGGAACCGGTCTCAGTAT
ATGCCAGCTTTCTCTCTATCTCATTATTCCATTTGTTGCAAAACTGTCTT
TGAAAAATGAAAAAATTCTAGTGGGTGTTTAATTTATATTTTAATTATTT
TTTTTTTATTTTTATGTGA
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protein sequence of SMED30022225-orf-1

>SMED30022225-orf-1 ID=SMED30022225-orf-1|Name=SMED30022225-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=221bp
MLSITEFVGVAATAFSLLQNCIILLIVRRIRGRGSSDHFSFFPYCANFAS
SICWLKYAFLIFDMPLIFSNIFSAVISGFIILFFYLYSQMKFNLIYPTLI
GSFLITIGLFFNVNDAVESQISFLQVYCPLMSVMAFGAPLSAITSVWRNK
SLNQMSFSLCFSNFLIGILWVTYGMLKDDYSLMICNLLGTGLSICQLSLY
LIIPFVAKLSLKNEKILVGV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
Vocabulary: INTERPRO
TermDefinition
IPR004316SWEET_sugar_transpr
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0005886plasma membrane
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0008643carbohydrate transport
GO:0034219carbohydrate transmembrane transport
Vocabulary: molecular function
TermDefinition
GO:0051119sugar transmembrane transporter activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.20.1280.290coord: 28..115
e-value: 2.0E-12
score: 49.0
NoneNo IPR availablePANTHERPTHR10791:SF30SUGAR TRANSPORTER SWEET1coord: 19..115
NoneNo IPR availablePANTHERPTHR10791RAG1-ACTIVATING PROTEIN 1coord: 19..115
NoneNo IPR availableTMHMMTMhelixcoord: 5..27
NoneNo IPR availableTMHMMTMhelixcoord: 66..88
NoneNo IPR availableTMHMMTMhelixcoord: 34..56
NoneNo IPR availableTMHMMTMhelixcoord: 95..117
IPR004316SWEET sugar transporterPFAMPF03083MtN3_slvcoord: 34..114
e-value: 2.4E-20
score: 72.3