Charged multivesicular body protein 4b

Overview
NameCharged multivesicular body protein 4b
Smed IDSMED30022189
Length (bp)1398
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Charged multivesicular body protein 4b (SMED30022189) t-SNE clustered cells

Violin plots show distribution of expression levels for Charged multivesicular body protein 4b (SMED30022189) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30022189

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30022189SMESG000042754.1 SmedASXL_063821SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
reproductive organSMED30022189SMESG000042643.1 Contig30953newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30022189SMESG000042643.1 Contig30953uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Human
Match: CHMP4B (charged multivesicular body protein 4B [Source:HGNC Symbol;Acc:HGNC:16171])

HSP 1 Score: 202.216 bits (513), Expect = 6.911e-62
Identity = 120/204 (58.82%), Postives = 163/204 (79.90%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN-EDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            +P EA+++L+D +EML KKQ FLEKKIE E+  AK+HG KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H NMDIDKV+++M DI +QQELA+EI+ +IS PVGFG ++D+DELMAELE L++E L + L +++  + + LP+VPS  +  SKP A+K + +D +++EL+NWA 
Sbjct:   21 TPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSIAL-PSKP-AKKKEEEDDDMKELENWAG 222
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Human
Match: CHMP4A (charged multivesicular body protein 4A [Source:HGNC Symbol;Acc:HGNC:20274])

HSP 1 Score: 193.741 bits (491), Expect = 1.322e-58
Identity = 113/221 (51.13%), Postives = 165/221 (74.66%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN----EDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            + + FGK K +K  +P EA++KLK+ +++L KKQ FLE+KI+ E++TAK++G KNKRAALQAL RKKR+E+QL Q DG L+T+EFQ EA+ENATTN E+L+ M+ A+ ++K ++Q+MDIDKV+++M DITEQQE+A++I+D+IS P+GFG D D+DEL+ ELE L++E L ++L  V     E  ++LPSVPS  +      A K    ++ L++L  W S
Sbjct:    4 LGRLFGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEPSVKLPSVPSTHLPAG--PAPKVDEDEEALKQLAEWVS 222
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Human
Match: CHMP4A (charged multivesicular body protein 4A [Source:HGNC Symbol;Acc:HGNC:20274])

HSP 1 Score: 193.741 bits (491), Expect = 1.322e-58
Identity = 113/221 (51.13%), Postives = 165/221 (74.66%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN----EDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            + + FGK K +K  +P EA++KLK+ +++L KKQ FLE+KI+ E++TAK++G KNKRAALQAL RKKR+E+QL Q DG L+T+EFQ EA+ENATTN E+L+ M+ A+ ++K ++Q+MDIDKV+++M DITEQQE+A++I+D+IS P+GFG D D+DEL+ ELE L++E L ++L  V     E  ++LPSVPS  +      A K    ++ L++L  W S
Sbjct:    4 LGRLFGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEPSVKLPSVPSTHLPAG--PAPKVDEDEEALKQLAEWVS 222
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Human
Match: CHMP4A (charged multivesicular body protein 4A [Source:HGNC Symbol;Acc:HGNC:20274])

HSP 1 Score: 195.282 bits (495), Expect = 1.427e-58
Identity = 114/226 (50.44%), Postives = 167/226 (73.89%), Query Frame = 2 
Query:  554 LFFNEMNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN----EDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            L  + + + FGK K +K  +P EA++KLK+ +++L KKQ FLE+KI+ E++TAK++G KNKRAALQAL RKKR+E+QL Q DG L+T+EFQ EA+ENATTN E+L+ M+ A+ ++K ++Q+MDIDKV+++M DITEQQE+A++I+D+IS P+GFG D D+DEL+ ELE L++E L ++L  V     E  ++LPSVPS  +      A K    ++ L++L  W S
Sbjct:   42 LAMSGLGRLFGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEPSVKLPSVPSTHLPAG--PAPKVDEDEEALKQLAEWVS 265
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Human
Match: CHMP4A (charged multivesicular body protein 4A [Source:HGNC Symbol;Acc:HGNC:20274])

HSP 1 Score: 195.282 bits (495), Expect = 1.427e-58
Identity = 114/226 (50.44%), Postives = 167/226 (73.89%), Query Frame = 2 
Query:  554 LFFNEMNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN----EDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            L  + + + FGK K +K  +P EA++KLK+ +++L KKQ FLE+KI+ E++TAK++G KNKRAALQAL RKKR+E+QL Q DG L+T+EFQ EA+ENATTN E+L+ M+ A+ ++K ++Q+MDIDKV+++M DITEQQE+A++I+D+IS P+GFG D D+DEL+ ELE L++E L ++L  V     E  ++LPSVPS  +      A K    ++ L++L  W S
Sbjct:   42 LAMSGLGRLFGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEPSVKLPSVPSTHLPAG--PAPKVDEDEEALKQLAEWVS 265
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Celegans
Match: vps-32.1 (Related to yeast Vacuolar Protein Sorting factor [Source:UniProtKB/TrEMBL;Acc:Q18886])

HSP 1 Score: 194.512 bits (493), Expect = 2.246e-59
Identity = 111/220 (50.45%), Postives = 158/220 (71.82%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPS---NEVGTSKPKAEKGKTKDKELEELQNWAS 1219
              K FG +K +  S+P E+++KL++ +EML+KKQ FLEKK+ +E + A ++G KNKR ALQ L RK+ +EKQL  +DG+L+TI +Q EA+ENA+TN E+L  M  AS ALK++H NMDID+V+D+M+DI EQQE+A EIA++ISNPVGF    DDD+LM ELE L++E L ++L       + LP  P+     V  S+P+A   K  DK+LE+L++WA+
Sbjct:    4 FGKIFGGRKQEAPSTPQESIQKLRETEEMLEKKQEFLEKKVIDEKQNAVKYGTKNKRMALQCLNRKRNFEKQLAHIDGVLSTIGYQREALENASTNAEVLNVMGTASKALKAAHNNMDIDQVHDLMEDIAEQQEVANEIAEAISNPVGFSTAVDDDDLMRELEALEQEELDKELLDARAPPVTLPDTPNIALPAVPASRPRA---KEADKDLEDLESWAN 220
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Celegans
Match: vps-32.1 (Related to yeast Vacuolar Protein Sorting factor [Source:UniProtKB/TrEMBL;Acc:Q18886])

HSP 1 Score: 194.512 bits (493), Expect = 2.246e-59
Identity = 111/220 (50.45%), Postives = 158/220 (71.82%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPS---NEVGTSKPKAEKGKTKDKELEELQNWAS 1219
              K FG +K +  S+P E+++KL++ +EML+KKQ FLEKK+ +E + A ++G KNKR ALQ L RK+ +EKQL  +DG+L+TI +Q EA+ENA+TN E+L  M  AS ALK++H NMDID+V+D+M+DI EQQE+A EIA++ISNPVGF    DDD+LM ELE L++E L ++L       + LP  P+     V  S+P+A   K  DK+LE+L++WA+
Sbjct:    4 FGKIFGGRKQEAPSTPQESIQKLRETEEMLEKKQEFLEKKVIDEKQNAVKYGTKNKRMALQCLNRKRNFEKQLAHIDGVLSTIGYQREALENASTNAEVLNVMGTASKALKAAHNNMDIDQVHDLMEDIAEQQEVANEIAEAISNPVGFSTAVDDDDLMRELEALEQEELDKELLDARAPPVTLPDTPNIALPAVPASRPRA---KEADKDLEDLESWAN 220
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Celegans
Match: R12C12.5 (pep chromosome:WBcel235:II:6044145:6045218:-1 gene:WBGene00020025.1 transcript:R12C12.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:R12C12.5)

HSP 1 Score: 117.472 bits (293), Expect = 3.703e-30
Identity = 80/236 (33.90%), Postives = 133/236 (56.36%), Query Frame = 2 
Query:  560 FNEMNKFFGKKKDD-------------KESSPV--EALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKT-KDKELEELQNWAS 1219
            F +M+ FF +  ++             K  +P   EA+  L+D +E+L KKQ + E +IE E+E+AK++   NK+ AL AL +KK YE++L ++DG+LT +E Q  A+EN   + E++  + + +  LK  H  MDIDKV+D+MD+I +   +++E+ ++IS P+G   D +D+ +    EL          TK+ +    LP  PS E+  +     +GK  K   +EEL+ WA+
Sbjct:    3 FKKMSWFFDRMHEEAHKIKEKIKEKSRKRKAPTADEAIGNLRDAEELLIKKQEYFELRIEQEVESAKKYMKTNKKMALAALRKKKHYEQELSRIDGVLTKLEAQRTALENVGMHNEVIDVLGKTTETLKKEHAKMDIDKVHDLMDEIADGLAMSEELNEAISAPIGDVAD-EDELMQELQELQDNVADLSTTTKLPDVPATLPEAPSGELTRA---GRRGKFRKMSTMEELEQWAA 234
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Celegans
Match: vps-20 (Related to yeast Vacuolar Protein Sorting factor [Source:UniProtKB/TrEMBL;Acc:Q9BL60])

HSP 1 Score: 53.9138 bits (128), Expect = 3.540e-8
Identity = 68/220 (30.91%), Postives = 109/220 (49.55%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVE-------ALRKLKD-VKEMLDKKQMFLEKKIENEIETAK---RHGMKNKRAALQALGRKKRY-EKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTKDKE 1192
            M   F KK+   +S+PV        AL+  +D +K+M+ +K+  LEK    E + AK   + G K+ RA L  L +KKRY EK + Q    L+ IE  +  +E A     +   ++Q + ALK  +Q  DID+++ IM++  E  E  +EI++ +S  +    D  D            E   E L       ++LP  PS+E+    P+AE+ + K+KE
Sbjct:    1 MGGIFSKKEKSPKSAPVSDQDNAILALKTQRDKMKQMIKRKENCLEK----ERQLAKQLIKDGRKD-RALL--LLKKKRYQEKIIDQTLNHLSKIEQMVNDLEFAEVQQRVTDGLRQGNEALKKMNQLFDIDEIDRIMEETKEAAEYQEEISNMLSGQLS-NTDVSD-----------VEKELEDLLAAEWGTVQLPEAPSHEL----PEAERERQKEKE 197
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Fly
Match: shrb (gene:FBgn0086656 transcript:FBtr0088623)

HSP 1 Score: 180.259 bits (456), Expect = 9.650e-54
Identity = 95/162 (58.64%), Postives = 124/162 (76.54%), Query Frame = 2 
Query:  557 FFNEMNKFFGKKKDDKESSPV--EALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDD 1036
            FF +M   FG KK   E +P   EA++KL++ + ML KKQ FLE KIE+E+  A+++  KNKR ALQAL +KKR EKQLQQ+DG L+TIE Q EA+E+A TNT +L  MK A+ ALK +HQNMD+DKV+D+MDDI EQQ++A+EI+D+ISNPV FG D DD+
Sbjct:    3 FFGKM---FGGKK---EVAPTTGEAIQKLRETENMLIKKQEFLEAKIEDELNIARKNASKNKRVALQALKKKKRLEKQLQQIDGTLSTIEMQREALESANTNTAVLTTMKNAADALKRAHQNMDVDKVHDMMDDIAEQQDVAREISDAISNPVAFGADLDDE 158
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Fly
Match: Vps20 (gene:FBgn0034744 transcript:FBtr0071856)

HSP 1 Score: 53.1434 bits (126), Expect = 1.087e-7
Identity = 49/169 (28.99%), Postives = 85/169 (50.30%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPV------EALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYE--------KQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDD 1033
            M   FGK    K+++P       +A+ +LK  ++ L + Q  +E ++EN+   A++   + ++   + L RKK+Y+        KQL+ ++ +   IEF       A    ++L  +K  + ALK  H+ +DID+V  IMD+  E  E  +EI D+I   V    D +D
Sbjct:    1 MGALFGKT--SKKTAPSRITDQDKAVLQLKQQRDRLKQYQKRIETQLENDRLLARKCLQQGRKDRAKLLLRKKKYQESLLTNADKQLENLEKLAADIEF-------AQVEMKVLDGLKAGNAALKKVHEMLDIDEVERIMDETREGIEKQQEI-DAILTDVLTTQDEED 159
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Fly
Match: Vps20 (gene:FBgn0034744 transcript:FBtr0308602)

HSP 1 Score: 53.1434 bits (126), Expect = 1.087e-7
Identity = 49/169 (28.99%), Postives = 85/169 (50.30%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPV------EALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYE--------KQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDD 1033
            M   FGK    K+++P       +A+ +LK  ++ L + Q  +E ++EN+   A++   + ++   + L RKK+Y+        KQL+ ++ +   IEF       A    ++L  +K  + ALK  H+ +DID+V  IMD+  E  E  +EI D+I   V    D +D
Sbjct:    1 MGALFGKT--SKKTAPSRITDQDKAVLQLKQQRDRLKQYQKRIETQLENDRLLARKCLQQGRKDRAKLLLRKKKYQESLLTNADKQLENLEKLAADIEF-------AQVEMKVLDGLKAGNAALKKVHEMLDIDEVERIMDETREGIEKQQEI-DAILTDVLTTQDEED 159
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Fly
Match: Vps60 (gene:FBgn0036740 transcript:FBtr0333123)

HSP 1 Score: 53.1434 bits (126), Expect = 1.166e-7
Identity = 62/206 (30.10%), Postives = 100/206 (48.54%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIEN-EIETAK--------RHG-MKN--KRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGT 1150
            MN+ FG+ K      P E    L D    +D +   +E+KI N E E  K        R G  KN  K+ AL+ L +KK YE+Q + +      +E    A ++       + AMK     +K+ ++ ++ID++ DI DD+ +  E A E+ +++    G   + DDD+L AEL+ L +E   +  T   +D ++ P  PS E G 
Sbjct:    1 MNRLFGRGK------PKEPGPSLNDCIAGVDARATNIEEKISNLEAELRKYREQMSKMREGPAKNSVKQKALRVLKQKKAYEQQAESLRNQSFNMEQANYAAQSLKDTQATVAAMKDGVKQMKTEYKKINIDQIEDIQDDMADMFEQADEVQEALGRTYGM-PEVDDDDLQAELDALGDEIALDDDTSYLDDVVKAPEAPSREPGA 199
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Fly
Match: Vps60 (gene:FBgn0036740 transcript:FBtr0075201)

HSP 1 Score: 53.1434 bits (126), Expect = 1.166e-7
Identity = 62/206 (30.10%), Postives = 100/206 (48.54%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIEN-EIETAK--------RHG-MKN--KRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGT 1150
            MN+ FG+ K      P E    L D    +D +   +E+KI N E E  K        R G  KN  K+ AL+ L +KK YE+Q + +      +E    A ++       + AMK     +K+ ++ ++ID++ DI DD+ +  E A E+ +++    G   + DDD+L AEL+ L +E   +  T   +D ++ P  PS E G 
Sbjct:    1 MNRLFGRGK------PKEPGPSLNDCIAGVDARATNIEEKISNLEAELRKYREQMSKMREGPAKNSVKQKALRVLKQKKAYEQQAESLRNQSFNMEQANYAAQSLKDTQATVAAMKDGVKQMKTEYKKINIDQIEDIQDDMADMFEQADEVQEALGRTYGM-PEVDDDDLQAELDALGDEIALDDDTSYLDDVVKAPEAPSREPGA 199
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Zebrafish
Match: chmp4ba (charged multivesicular body protein 4Ba [Source:NCBI gene;Acc:393164])

HSP 1 Score: 196.052 bits (497), Expect = 1.065e-59
Identity = 116/202 (57.43%), Postives = 163/202 (80.69%), Query Frame = 2 
Query:  614 PVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            P EA+++L++ +EML KKQ FLEKKIE E+ TAK++G KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE++K M  A+ A+K++H NMDIDKV+++M DITEQQELA+EI+D+IS PVGFG ++D+DEL+AELE L++E L + L ++  D++ LP+VPS  +  S+P  +K +  + ++++L+ WA+
Sbjct:   20 PQEAIQRLRETEEMLTKKQEFLEKKIEQELVTAKKNGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENAHTNTEVIKNMGYAAKAMKAAHDNMDIDKVDELMQDITEQQELAQEISDAISKPVGFGEEFDEDELLAELEELEQEELDKNLLEIG-DNVPLPNVPSTSL-PSRPAKKKEEEDEDDMKDLEAWAA 219
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Zebrafish
Match: chmp4bb (charged multivesicular body protein 4Bb [Source:NCBI gene;Acc:406766])

HSP 1 Score: 195.282 bits (495), Expect = 2.100e-59
Identity = 120/205 (58.54%), Postives = 163/205 (79.51%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN-EDDIRLPSVPSNEVGTSKPKAEKGK--TKDKELEELQNWA 1216
            +P EA++KL++ +EML KKQ FLEKKI+ E+  AK++G KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H+NMDIDKV+D+M DITEQQELA+EI+D+IS PVGFG ++D+DELMAELE L++E L + L +++  +D+ LP+VPSN +      A+K +    + ++EEL+ WA
Sbjct:   19 TPQEAIQKLRETEEMLAKKQDFLEKKIDAELLIAKKNGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKTAHENMDIDKVDDLMQDITEQQELAQEISDAISRPVGFGEEFDEDELMAELEELEQEELDKDLLQISGPEDVPLPNVPSNPLPKKTAVAQKKRQEEDEDDMEELKAWA 223
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Zebrafish
Match: chmp4c (charged multivesicular body protein 4C [Source:ZFIN;Acc:ZDB-GENE-050417-389])

HSP 1 Score: 173.326 bits (438), Expect = 8.569e-51
Identity = 104/207 (50.24%), Postives = 152/207 (73.43%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTK----DKELEELQNWAS 1219
            SP EA+ +L++ + ML KKQ +LE +IE EI  AK++G KNKRAALQAL RKKR+E+QL Q+DG L+TIEFQ E++ENATTNTE+LK M  A+ A+K  H+ +D+DK++ +M DITEQQE+A+EI+D+IS P  FG  +D+DEL+AEL  L++E+L+E +  +     RLPS P++++ +++P       K    D +++ L +WAS
Sbjct:   39 SPQEAINRLRETEAMLTKKQEYLESRIEQEIVIAKKNGTKNKRAALQALKRKKRFEQQLTQIDGTLSTIEFQRESLENATTNTEVLKNMGYAAKAIKGVHEKIDLDKIDSLMQDITEQQEVAQEISDAISQP--FGDQFDEDELLAELAELEQEDLEESMKSMG----RLPSAPTHKLPSTRPSHRATSKKRVEDDHDMKRLASWAS 239
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Zebrafish
Match: chmp4c (charged multivesicular body protein 4C [Source:ZFIN;Acc:ZDB-GENE-050417-389])

HSP 1 Score: 173.326 bits (438), Expect = 8.569e-51
Identity = 104/207 (50.24%), Postives = 152/207 (73.43%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTK----DKELEELQNWAS 1219
            SP EA+ +L++ + ML KKQ +LE +IE EI  AK++G KNKRAALQAL RKKR+E+QL Q+DG L+TIEFQ E++ENATTNTE+LK M  A+ A+K  H+ +D+DK++ +M DITEQQE+A+EI+D+IS P  FG  +D+DEL+AEL  L++E+L+E +  +     RLPS P++++ +++P       K    D +++ L +WAS
Sbjct:   39 SPQEAINRLRETEAMLTKKQEYLESRIEQEIVIAKKNGTKNKRAALQALKRKKRFEQQLTQIDGTLSTIEFQRESLENATTNTEVLKNMGYAAKAIKGVHEKIDLDKIDSLMQDITEQQEVAQEISDAISQP--FGDQFDEDELLAELAELEQEDLEESMKSMG----RLPSAPTHKLPSTRPSHRATSKKRVEDDHDMKRLASWAS 239
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Zebrafish
Match: chmp4bb (charged multivesicular body protein 4Bb [Source:NCBI gene;Acc:406766])

HSP 1 Score: 49.6766 bits (117), Expect = 1.058e-7
Identity = 25/44 (56.82%), Postives = 35/44 (79.55%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRA 742
            +P EA++KL++ +EML KKQ FLEKKI+ E+  AK++G KNKR 
Sbjct:   19 TPQEAIQKLRETEEMLAKKQDFLEKKIDAELLIAKKNGTKNKRG 62
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Xenopus
Match: fmn1 (formin 1 [Source:Xenbase;Acc:XB-GENE-940125])

HSP 1 Score: 207.994 bits (528), Expect = 3.433e-64
Identity = 127/219 (57.99%), Postives = 167/219 (76.26%), Query Frame = 2 
Query:  569 MNKFFGKK-KDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXV-NEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            + K FG   K  K  SP EA++KL+D +EML KKQ FLEK IE E+ TAK+HG KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H NMDI+KV+++M DI +QQELA+EI+D+IS PVGFG D+D+DELMAELE L++E L + L +V   + + LP+VP+  V  +KP  +K +  D ++ EL+NWA+
Sbjct:    4 IGKLFGTGGKGAKGPSPQEAIQKLRDTEEMLTKKQEFLEKMIEQELVTAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELMQDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQGPETVPLPNVPA-AVLPAKPVKKKQEEDDDDMRELENWAT 221
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Xenopus
Match: CHMP4C (charged multivesicular body protein 4C [Source:NCBI gene;Acc:100495807])

HSP 1 Score: 184.496 bits (467), Expect = 3.815e-55
Identity = 111/210 (52.86%), Postives = 160/210 (76.19%), Query Frame = 2 
Query:  593 KDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTK-DKELEELQNWAS 1219
            K+ K  S  EAL KL++ +EML KKQ +LEKKIE E+ TAK+HG KNKRAALQAL RKK+ EKQL Q+DG L+TIEFQ EA+EN+ TNTE+LK M  A+ A+K+ H+NMD++K++++M DI EQQ++A+EI+D+IS P GF  D+D+DELMAELE L++E++  ++      +++LPSVPS ++  S+P + + K + D +++ L  WA+
Sbjct:   19 KNRKGPSAQEALFKLRETEEMLTKKQEYLEKKIELELATAKKHGTKNKRAALQALKRKKKMEKQLAQIDGTLSTIEFQREALENSHTNTEVLKNMGYAAKAMKAVHENMDLEKIDNLMQDIHEQQDVAQEISDAISRPAGFCDDFDEDELMAELEELEQEDMNSQMA-----NVKLPSVPSTKL-PSRPASSRKKVEDDDDMQMLAAWAT 222
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Mouse
Match: Chmp4b (charged multivesicular body protein 4B [Source:MGI Symbol;Acc:MGI:1922858])

HSP 1 Score: 202.601 bits (514), Expect = 4.219e-62
Identity = 120/204 (58.82%), Postives = 163/204 (79.90%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN-EDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            +P EA+++L+D +EML KKQ FLEKKIE E+  AK+HG KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H NMDIDKV+++M DI +QQELA+EI+ +IS PVGFG ++D+DELMAELE L++E L + L +++  + + LP+VPS  +  SKP A+K + +D +++EL+NWA 
Sbjct:   21 TPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSVAL-PSKP-AKKKEEEDDDMKELENWAG 222
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Mouse
Match: Chmp4c (charged multivesicular body protein 4C [Source:MGI Symbol;Acc:MGI:1913621])

HSP 1 Score: 165.622 bits (418), Expect = 7.766e-48
Identity = 82/159 (51.57%), Postives = 120/159 (75.47%), Query Frame = 2 
Query:  563 NEMNKFF-GKKKDDKESSPV--EALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYD 1030
            +++ KFF G +     ++P   EAL +L++ +EML KKQ +LE +I+ E+  AK+HG +NKRAALQAL RKKR+EKQL Q+DG L+TIEFQ EA+EN+ TNTE+L+ M  A+ A+K+ H NMD++K++D+M DITEQQ++A+EI+++ S  V F   +D
Sbjct:    2 SKLGKFFKGTRSSRARAAPSAQEALARLRETEEMLAKKQEYLENRIQRELALAKKHGSQNKRAALQALKRKKRFEKQLTQVDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKAVHDNMDLNKIDDLMQDITEQQDIAQEISEAFSQRVQFADGFD 160
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Mouse
Match: Chmp4c (charged multivesicular body protein 4C [Source:MGI Symbol;Acc:MGI:1913621])

HSP 1 Score: 51.2174 bits (121), Expect = 3.817e-8
Identity = 26/62 (41.94%), Postives = 42/62 (67.74%), Query Frame = 2 
Query:  563 NEMNKFF-GKKKDDKESSPV--EALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKR 739
            +++ KFF G +     ++P   EAL +L++ +EML KKQ +LE +I+ E+  AK+HG +NKR
Sbjct:    2 SKLGKFFKGTRSSRARAAPSAQEALARLRETEEMLAKKQEYLENRIQRELALAKKHGSQNKR 63
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Mouse
Match: Chmp6 (charged multivesicular body protein 6 [Source:MGI Symbol;Acc:MGI:3583942])

HSP 1 Score: 53.1434 bits (126), Expect = 1.084e-7
Identity = 53/214 (24.77%), Postives = 108/214 (50.47%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAK---RHGMKNKRAALQALGRKKRYEKQL-QQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKA-EKGKTKDKEL 1195
            M   FG+KK  + +    A+ +LK  ++ L + Q  + +++E E   A+   R G K +RA L  L +KKRY +QL  + +  ++++E  ++++E      ++++ ++  +  L   HQ M I++V  I+D+  E  E  ++I + ++    F  + +D              + E+L  + ++ + LP VPS  +    P+A  K +++  EL
Sbjct:    1 MGNLFGRKKQSRVTEQDRAILQLKQQRDKLRQYQKRVTQQLERERALARQLLRDGRK-ERAKL--LLKKKRYREQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQVGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAG--NFTQEDED-------------AILEELNAITQEQMELPEVPSEPLPDRNPEAPAKARSRQAEL 196
[Close]
BLAST of Charged multivesicular body protein 4b vs. UniProt/SwissProt
Match: sp|Q6GL11|CHM4B_XENTR (Charged multivesicular body protein 4b OS=Xenopus tropicalis OX=8364 GN=chmp4b PE=2 SV=1)

HSP 1 Score: 210.69 bits (535), Expect = 1.983e-64
Identity = 128/219 (58.45%), Postives = 168/219 (76.71%), Query Frame = 2 
Query:  569 MNKFFGKK-KDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXV-NEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            + K FG   K  K  SP EA++KL+D +EML KKQ FLEKKIE E+ TAK+HG KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H NMDI+KV+++M DI +QQELA+EI+D+IS PVGFG D+D+DELMAELE L++E L + L +V   + + LP+VP+  V  +KP  +K +  D ++ EL+NWA+
Sbjct:    4 IGKLFGTGGKGAKGPSPQEAIQKLRDTEEMLTKKQEFLEKKIEQELVTAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELMQDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQGPETVPLPNVPA-AVLPAKPVKKKQEEDDDDMRELENWAT 221
[Close]
BLAST of Charged multivesicular body protein 4b vs. UniProt/SwissProt
Match: sp|Q5XGW6|CHM4B_XENLA (Charged multivesicular body protein 4b OS=Xenopus laevis OX=8355 GN=chmp4b PE=2 SV=1)

HSP 1 Score: 210.305 bits (534), Expect = 2.735e-64
Identity = 127/219 (57.99%), Postives = 168/219 (76.71%), Query Frame = 2 
Query:  569 MNKFFGKK-KDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXV-NEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            + K FG   K  K  SP EA++KL+D +EML KKQ FLEKKIE E+ TAK+HG KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H NMDI+KV+++M DI +QQELA+EI+D+IS PVGFG D+D+DELMAELE L++E L + L +V   + + LP+VP+  +  +KP  +K +  D ++ EL+NWA+
Sbjct:    4 IGKLFGTGGKGAKGPSPQEAIQKLRDTEEMLAKKQEFLEKKIEQELVTAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELMQDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQGPETVPLPNVPAASL-PAKPVKKKQEEDDDDMRELENWAT 221
[Close]
BLAST of Charged multivesicular body protein 4b vs. UniProt/SwissProt
Match: sp|Q9D8B3|CHM4B_MOUSE (Charged multivesicular body protein 4b OS=Mus musculus OX=10090 GN=Chmp4b PE=1 SV=2)

HSP 1 Score: 202.601 bits (514), Expect = 2.951e-61
Identity = 120/204 (58.82%), Postives = 163/204 (79.90%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN-EDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            +P EA+++L+D +EML KKQ FLEKKIE E+  AK+HG KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H NMDIDKV+++M DI +QQELA+EI+ +IS PVGFG ++D+DELMAELE L++E L + L +++  + + LP+VPS  +  SKP A+K + +D +++EL+NWA 
Sbjct:   21 TPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSVAL-PSKP-AKKKEEEDDDMKELENWAG 222
[Close]
BLAST of Charged multivesicular body protein 4b vs. UniProt/SwissProt
Match: sp|Q9H444|CHM4B_HUMAN (Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1)

HSP 1 Score: 202.216 bits (513), Expect = 3.319e-61
Identity = 120/204 (58.82%), Postives = 163/204 (79.90%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN-EDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            +P EA+++L+D +EML KKQ FLEKKIE E+  AK+HG KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H NMDIDKV+++M DI +QQELA+EI+ +IS PVGFG ++D+DELMAELE L++E L + L +++  + + LP+VPS  +  SKP A+K + +D +++EL+NWA 
Sbjct:   21 TPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSIAL-PSKP-AKKKEEEDDDMKELENWAG 222
[Close]
BLAST of Charged multivesicular body protein 4b vs. UniProt/SwissProt
Match: sp|A2VDY3|CHM4A_BOVIN (Charged multivesicular body protein 4a OS=Bos taurus OX=9913 GN=CHMP4A PE=2 SV=1)

HSP 1 Score: 197.978 bits (502), Expect = 1.503e-59
Identity = 116/221 (52.49%), Postives = 162/221 (73.30%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN----EDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            + + FG+ K +K  +P EA++KLK+ +++L KKQ FLE+KIE E++ AK+HG KNKRAALQAL RKKR E+QL Q DG L+T+EFQ EA+ENATTN E+L+ M+ A+  LK ++Q+MDIDKV+++M DITEQQE+A++I+D+IS PVGFG D D+DEL+ ELE L++E L  +L  V     E  + LPS PS  +  ++P A K    + EL++L  W S
Sbjct:    4 LGRLFGRGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIEQELQAAKKHGTKNKRAALQALRRKKRLEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQGLKKAYQDMDIDKVDELMADITEQQEVAQQISDAISRPVGFGDDVDEDELLEELEELEQEELARELLHVGDEEEEPPVALPSAPSTHL-PAEP-APKADEDEAELKQLAEWVS 222
[Close]
BLAST of Charged multivesicular body protein 4b vs. TrEMBL
Match: A0A2I4BWS6 (charged multivesicular body protein 4b OS=Austrofundulus limnaeus OX=52670 GN=chmp4b PE=4 SV=1)

HSP 1 Score: 215.312 bits (547), Expect = 7.750e-64
Identity = 126/216 (58.33%), Postives = 166/216 (76.85%), Query Frame = 2 
Query:  575 KFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXV-NEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            K FG  K  K  +  EA+ KL++ +EML KKQ FLEKKIE E+ TAK++G KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H+NMDIDKV+D+M DITEQQELA+EI+D IS PVGFG +YD+D+LMAELE L++E L + L ++   +D+ LPSVPS  +  SKP  +K +  + ++ +L+ WA+
Sbjct:    6 KMFGSNKSGKAPTAQEAIHKLRETEEMLAKKQEFLEKKIEQELLTAKKNGTKNKRAALQALKRKKRYEKQLTQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHENMDIDKVDDLMADITEQQELAQEISDVISRPVGFGEEYDEDDLMAELEELEQEELDKNLLEIKGTEDVPLPSVPSTSL-PSKPAKKKVEEDEDDMADLEAWAA 220
[Close]
BLAST of Charged multivesicular body protein 4b vs. TrEMBL
Match: A0A3P8X1E7 (Uncharacterized protein OS=Cynoglossus semilaevis OX=244447 PE=4 SV=1)

HSP 1 Score: 214.542 bits (545), Expect = 1.428e-63
Identity = 128/215 (59.53%), Postives = 163/215 (75.81%), Query Frame = 2 
Query:  578 FFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTK-DKELEELQNWAS 1219
            F G  K  KE SP +A++KL+D +EML KKQ FLEKKIE E++TAK+HG+KNKR ALQAL RKKRYE QL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ AL+++H+++D+D V+D+MDDITEQQELA EI+++IS PVGFG  YD+DELMAELE L++E L   L +V E D  LPSVPS    TS P     K + D ++ EL+ WA+
Sbjct:    8 FGGGGKGSKEPSPQQAIQKLRDTEEMLAKKQEFLEKKIEQEVQTAKKHGLKNKRVALQALKRKKRYETQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKALQAAHKSIDVDNVHDLMDDITEQQELANEISEAISKPVGFGEQYDEDELMAELEDLEQEELDRNLLEVPETDT-LPSVPS----TSLPARPVMKEEDDDDVAELEAWAA 217
[Close]
BLAST of Charged multivesicular body protein 4b vs. TrEMBL
Match: A0A433TYK3 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_005590 PE=4 SV=1)

HSP 1 Score: 214.157 bits (544), Expect = 1.887e-63
Identity = 122/215 (56.74%), Postives = 164/215 (76.28%), Query Frame = 2 
Query:  575 KFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            K FG    DK  +P E +++L++V+EML KK  FLEKKIE+E+  AK++G KNKR ALQAL RKKRYEKQLQQ+DG L+TIEFQ EA+ENA+TNTE+LK M  AS ALKS+H N+D+D+V+D+MDD+ EQQE+A EI+++ISNPVGFG D D+D+L+AELE L++E L  +L +V      LPSVP+ E   S+P   +   +D +++EL+ WAS
Sbjct:    4 KLFGGGNKDKAPTPQEGIQRLREVEEMLMKKSDFLEKKIESEVNIAKKNGTKNKRVALQALKRKKRYEKQLQQIDGTLSTIEFQREALENASTNTEVLKVMGVASKALKSAHNNLDVDQVHDLMDDVAEQQEVANEISEAISNPVGFGQDVDEDDLLAELEELEQEELDRQLLEVGGTAEDLPSVPTAEPAESRPAKARQVEEDDDMKELEMWAS 218
[Close]
BLAST of Charged multivesicular body protein 4b vs. TrEMBL
Match: A0A401T7E9 (Uncharacterized protein OS=Chiloscyllium punctatum OX=137246 GN=chiPu_0017108 PE=4 SV=1)

HSP 1 Score: 213.772 bits (543), Expect = 3.401e-63
Identity = 124/219 (56.62%), Postives = 171/219 (78.08%), Query Frame = 2 
Query:  569 MNKFFGKK-KDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXV-NEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
              K FG   K  K  +P EA++KL+D +E+L KKQ FLEKKI+ E+  A++HG KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H+NMDIDKV+++M DITEQQELA+EI+++IS PVGFG D+D+DELMAELE L++E L + L ++   +++ LP+VPS  +  + P A+K + +D +++EL+NWA+
Sbjct:    4 FGKLFGSSAKAGKGPTPQEAIQKLRDTEELLTKKQEFLEKKIDQELLAARKHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHENMDIDKVDELMQDITEQQELAQEISEAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEIGGAENVPLPNVPSTSLPAT-PAAKKKEEEDSDMQELENWAA 221
[Close]
BLAST of Charged multivesicular body protein 4b vs. TrEMBL
Match: V4C976 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_203722 PE=4 SV=1)

HSP 1 Score: 213.001 bits (541), Expect = 5.513e-63
Identity = 120/217 (55.30%), Postives = 161/217 (74.19%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            + K FG  K D+  +P E +++L+D++EML KK  FLEKK++ E+ TAK+HG KNKR ALQAL RKKRYEKQLQ +DG L+TIE+Q EA+ENA+TNTE+LK M  A+ ALK +H NMD+DKV+D+MD++ EQ E+A EI+D+ISNP+GFG D DDD+LMAELE L++++++E+L  V      LPSVP +E    K KA      D E+ +L  WAS
Sbjct:    4 LQKLFGSGKKDQAPTPQEGIQRLRDIEEMLTKKSDFLEKKVDQELATAKKHGTKNKRVALQALKRKKRYEKQLQNIDGTLSTIEYQREALENASTNTEVLKVMGSAAKALKGAHNNMDVDKVHDLMDEVAEQNEIANEISDAISNPIGFGQDVDDDDLMAELEELEQQDIEEQLLDVTGPSADLPSVPVSE-PVEKRKAAVAD-DDDEMNQLAAWAS 218
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Cavefish
Match: chmp4bb (charged multivesicular body protein 4c [Source:NCBI gene;Acc:103026801])

HSP 1 Score: 199.519 bits (506), Expect = 4.172e-61
Identity = 120/203 (59.11%), Postives = 161/203 (79.31%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXV-NEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWA 1216
            +P EA++KL++ + ML KKQ FLE+KI  E+ TAK++G KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++HQNMDIDKV+D+M DITEQQELA+EI+D+IS PVGFG ++D+DELMAELE L++E L   L ++   +++ LPSVPS  +  SKP  ++ +  + ++EEL+ WA
Sbjct:   19 TPQEAIQKLRETEAMLTKKQEFLEQKISAELLTAKKNGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKNAHQNMDIDKVDDLMQDITEQQELAQEISDAISKPVGFGEEFDEDELMAELEELEQEELDNTLLEIGGTENVPLPSVPSTSL-PSKPTKKREEEDEDDMEELKAWA 220
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Cavefish
Match: ENSAMXT00000057406.1 (charged multivesicular body protein 4b [Source:NCBI gene;Acc:103043292])

HSP 1 Score: 195.667 bits (496), Expect = 1.456e-59
Identity = 120/219 (54.79%), Postives = 167/219 (76.26%), Query Frame = 2 
Query:  569 MNKFFGKK-KDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXV-NEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
              K FG   K  K  SP EA+++L+D +EML KKQ FLEKKI+ E+ TAKR+G KNKRAAL AL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE++K M  A+ A+K++H NMDIDKV+++M DITEQQELA+EI+D+IS PVGF  ++D+DEL+AELE L++E L + L ++   +++ LP+VPS  +  S+P  +K +  + ++++L+ WA+
Sbjct:    4 FGKLFGSGGKGGKAPSPQEAIQRLRDTEEMLTKKQEFLEKKIDQELITAKRNGTKNKRAALLALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVIKNMGFAAKAMKAAHDNMDIDKVDELMQDITEQQELAQEISDAISKPVGFAEEFDEDELLAELEELEQEELDKNLLEIGGTENVLLPNVPSTSL-PSRPAKKKEEEDEDDIKDLEAWAA 221
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Cavefish
Match: chmp4c (charged multivesicular body protein 4C [Source:ZFIN;Acc:ZDB-GENE-050417-389])

HSP 1 Score: 122.865 bits (307), Expect = 5.745e-32
Identity = 91/206 (44.17%), Postives = 137/206 (66.50%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRK--KRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTKDK-ELEELQNWAS 1219
            SP EA+ +L++ + ML KKQ +LEKKIE EI  AK++G KNKR   +A+  +  K Y KQL  ++    ++ FQ     NA TNTE+LK M  A+ A+K  HQN+D+D ++ +M DITEQQE+A+EI+D+IS P  FG ++D+DEL+AEL  L++E L+E +  +     +LPSVPS+++  S P     + +D+ +++ L  WAS
Sbjct:   47 SPQEAINRLRETEAMLTKKQEYLEKKIEQEIIIAKKNGTKNKRVTCEAIVWEHLKLYLKQLVGLE----SLHFQ-----NANTNTEVLKNMSYAAKAIKGVHQNIDLDNIDSLMADITEQQEIAREISDAISQP--FGSEFDEDELLAELAELEQEELEESMKNMG----KLPSVPSSKL-PSVPSTRLKRVEDEDDMKTLAAWAS 236
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006536.1 (pep scaffold:Pmarinus_7.0:GL484585:4905:9162:1 gene:ENSPMAG00000005909.1 transcript:ENSPMAT00000006536.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 137.887 bits (346), Expect = 3.806e-39
Identity = 67/96 (69.79%), Postives = 81/96 (84.38%), Query Frame = 2 
Query:  743 ALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYD 1030
            AL AL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++HQNMDIDKV+++M DI EQQELA+EI+D+IS PVGFG D D
Sbjct:    1 ALAALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKTMGFAAKAMKNAHQNMDIDKVDELMGDIHEQQELAQEISDAISKPVGFGDDMD 96
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Yeast
Match: SNF7 (One of four subunits of the ESCRT-III complex; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes; ESCRT-III stands for endosomal sorting complex required for transport III [Source:SGD;Acc:S000004015])

HSP 1 Score: 93.9745 bits (232), Expect = 2.277e-22
Identity = 68/213 (31.92%), Postives = 121/213 (56.81%), Query Frame = 2 
Query:  578 FFGKKKDDKES--SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMK-NKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXX-----------VNEDDIRLPSVPSNEVGTSKPKAEKG 1174
             FG    + ++  SP +A+ +L++   +L KKQ  L  +I N+   A+    K NK  A  AL +KK  E+ L +++G + ++E Q+ ++E+A  N E ++AM++ + A+K+ H  +DIDKV++ MD+I EQ EL  EI+D+IS P+  G +  D++ + E   +  +    + T            ++E+ + LPSVPSN++  S+   + G
Sbjct:    5 LFGWTSSNAKNKESPTKAIVRLREHINLLSKKQSHLRTQITNQENEARIFLTKGNKVMAKNALKKKKTIEQLLSKVEGTMESMEQQLFSIESANLNLETMRAMQEGAKAMKTIHSGLDIDKVDETMDEIREQVELGDEISDAISRPLITGANEVDEDELDEELDMLAQENANQETSKIVNNNVNAAPISENKVSLPSVPSNKIKQSENSVKDG 217
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Nematostella
Match: EDO47281 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMK0])

HSP 1 Score: 176.022 bits (445), Expect = 1.433e-52
Identity = 117/219 (53.42%), Postives = 154/219 (70.32%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPV--EALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            M   FGKKK   E+ P   EA++KL+  +E+L KK  FLEKKIENE++ AK++  KNKR AL AL RKKR EKQL Q+DG L+TIEFQ EA+E A TNTE+LK M  A+ ALK++HQ +D+D V+D+MDDI EQ ELA EI+ +IS P GFG D D+DEL AEL+ L++  + +++  +      LPSVP  E+  S+P   K KT+D +L EL+ WAS
Sbjct:    1 MWSMFGKKK---ETPPTTQEAIQKLRSTEELLQKKSDFLEKKIENELQIAKQNASKNKRTALNALKRKKRLEKQLNQIDGTLSTIEFQREALEGANTNTEVLKNMSYAAKALKAAHQQLDVDDVHDMMDDIQEQTELADEISRAISEPAGFGMDIDEDELNAELDELEQSEIDKQILDIGPTSTGLPSVPETEL-PSRPAKAKKKTEDDDLAELEAWAS 215
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Nematostella
Match: EDO42779 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0Q4])

HSP 1 Score: 127.872 bits (320), Expect = 2.509e-34
Identity = 98/199 (49.25%), Postives = 145/199 (72.86%), Query Frame = 2 
Query:  620 EALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTKDK-ELEELQNW 1213
            +A+ KL++ +++L+KKQ +LE++IE E  TAK +  KNKR ALQAL RKKR EKQL Q+DG L+TIEFQ +A+EN++TNTE++K+M  A+ ALK  H+ +DID V+D+MDD+ EQ +L+ EI+ +I N VG   D D+ ++M+EL  L++E + ++L +V +   RLP+VPS    T  P A+K K  D+ EL+EL+ W
Sbjct:   31 QAIWKLRETEKLLEKKQEYLEQRIEIETNTAKANVKKNKRIALQALKRKKRLEKQLSQIDGTLSTIEFQRDALENSSTNTEVVKSMSFAANALKEVHKTLDIDDVHDVMDDVQEQAQLSDEISQAI-NFVG-SQDIDESDIMSELAELEQEVIDKELIQVKKPGPRLPNVPS----TKLPAAQKKKRSDEDELKELEAW 223
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Nematostella
Match: EDO47972 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKV7])

HSP 1 Score: 56.225 bits (134), Expect = 3.513e-9
Identity = 63/207 (30.43%), Postives = 101/207 (48.79%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVE---ALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQL-QQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGK 1177
            M  FF +KK+ ++    E   A+  LK  ++ L K Q  +   +E E + AK    + KR   + L +KKRY++QL Q+ D  L  +E  ++ +E A    ++++ +K  +  L   H+ M I+ V  IMD+  E  E  KEI D +S       + +D  L     L +  + K       E +I LP  PS E G ++ KA+K K
Sbjct:    1 MGIFFSRKKEPEKPKITEQDKAVLALKQQRDKLKKYQKKINVNLEKERQLAKELLQQGKRNKAKLLLKKKRYQEQLLQRTDNQLDNLEKLVQEIEFAQVQIKVVEGLKTGNECLNQLHEMMSIEDVERIMDETKEAVEYQKEIDDLLSG--SLTSEDEDAVLQELEALTESISEKFPDVPKEEPEISLPEAPSTEPGVAR-KAQKEK 204
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Nematostella
Match: EDO49015 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHP5])

HSP 1 Score: 54.6842 bits (130), Expect = 1.451e-8
Identity = 52/172 (30.23%), Postives = 81/172 (47.09%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKI----------ENEIETAKRHGMKN--KRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNT-----EILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDD 1033
            MN+ FGK K      P E    L D    +D +   +EKKI          +++++  +    KN  K+ AL+ L +KK+YE QL+     L    F +E   N TT T       + AMK     +K  ++ ++ID++ DI DD+ +  E A EI +S+    G   D D+
Sbjct:    1 MNRLFGKGK------PKEPPPNLTDCISNVDSRGESIEKKIAKLDQELLKYKDQMKKMRDGPSKNMLKQRALRVLKQKKQYENQLEG----LRQQSFNMEQA-NFTTQTLKDTKHTVDAMKTGLKEMKKEYKKLNIDQIEDIQDDMADMMEQANEIQESLGRTYGLPDDIDE 161
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Medaka
Match: ENSORLT00000016086.2 (charged multivesicular body protein 4b [Source:NCBI gene;Acc:101173541])

HSP 1 Score: 203.371 bits (516), Expect = 1.495e-62
Identity = 121/205 (59.02%), Postives = 163/205 (79.51%), Query Frame = 2 
Query:  608 SSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXV-NEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            ++P EA++KL++ +EML KKQ FLEKKIE E+ TAK++G KNKRAALQAL RKKRYEKQL Q+DG L+TIEFQ EA+ENA TNTE+LK M  A+ A+K++H+NMDIDKV+D+M +ITEQQE+A+EI+D IS PVGFG DYD+DEL+AELE L++E L + L ++    D+ LPSVPS  +  SKP  +K +  + ++ +L+ WA+
Sbjct:   18 ATPQEAIQKLRETEEMLAKKQDFLEKKIEQELITAKKNGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHENMDIDKVDDLMAEITEQQEVAQEISDVISRPVGFGEDYDEDELLAELEDLEQEELDKNLLEIKGTADVPLPSVPSTSL-PSKPAKKKQEEDEDDMADLEAWAT 221
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Medaka
Match: chmp4bb (charged multivesicular body protein 4B [Source:NCBI gene;Acc:101163168])

HSP 1 Score: 194.126 bits (492), Expect = 4.385e-59
Identity = 116/203 (57.14%), Postives = 163/203 (80.30%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXV-NEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWA 1216
            SP EA++KL++ +EML KKQ FLEKKI+ E++ AK++G KNKRAALQAL RKKRYEKQL Q+DG ++TIEFQ EA+ENA TNTE+LK M  A+ A+KS+H+NMDI+KV+D+M DITEQQELA+EI+D+IS PVGFG ++D+DEL+AEL+ L++E L + L ++   +++ LP+VPS  +  S+P   + +  + ++E+LQ WA
Sbjct:   19 SPQEAIQKLRETEEMLTKKQEFLEKKIDQELQIAKKNGTKNKRAALQALKRKKRYEKQLAQIDGTISTIEFQREALENANTNTEVLKNMGLAAKAMKSAHENMDINKVDDLMQDITEQQELAQEISDAISKPVGFGEEFDEDELLAELDELEQEELDKNLLEIGGPENVPLPNVPSTSL-PSRPA--RKEEDEDDMEDLQRWA 218
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Medaka
Match: chmp4c (charged multivesicular body protein 4c [Source:NCBI gene;Acc:101156446])

HSP 1 Score: 172.94 bits (437), Expect = 6.226e-51
Identity = 86/134 (64.18%), Postives = 110/134 (82.09%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVG 1012
            S  EA+ +L++ +EML KKQ +LEKKIE EI TAK+HG KNKRAALQAL RKKR E+QL Q+DG L+TIEFQ EA+EN+ TNTE+LK M  A+ A+K  HQNMD+DK++D+M DITEQQE+A+EI+++IS P G
Sbjct:   24 SAQEAIHRLRETEEMLTKKQEYLEKKIEQEIATAKKHGTKNKRAALQALKRKKRLEQQLAQIDGTLSTIEFQREALENSHTNTEVLKNMGFAAKAMKQVHQNMDLDKIDDLMQDITEQQEVAQEISEAISRPFG 157
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Medaka
Match: chmp4c (charged multivesicular body protein 4c [Source:NCBI gene;Acc:101156446])

HSP 1 Score: 172.94 bits (437), Expect = 6.226e-51
Identity = 86/134 (64.18%), Postives = 110/134 (82.09%), Query Frame = 2 
Query:  611 SPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVG 1012
            S  EA+ +L++ +EML KKQ +LEKKIE EI TAK+HG KNKRAALQAL RKKR E+QL Q+DG L+TIEFQ EA+EN+ TNTE+LK M  A+ A+K  HQNMD+DK++D+M DITEQQE+A+EI+++IS P G
Sbjct:   24 SAQEAIHRLRETEEMLTKKQEYLEKKIEQEIATAKKHGTKNKRAALQALKRKKRLEQQLAQIDGTLSTIEFQREALENSHTNTEVLKNMGFAAKAMKQVHQNMDLDKIDDLMQDITEQQEVAQEISEAISRPFG 157
[Close]
BLAST of Charged multivesicular body protein 4b vs. Ensembl Medaka
Match: chmp4bb (charged multivesicular body protein 4B [Source:NCBI gene;Acc:101163168])

HSP 1 Score: 143.665 bits (361), Expect = 1.772e-39
Identity = 91/161 (56.52%), Postives = 127/161 (78.88%), Query Frame = 2 
Query:  740 AALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXV-NEDDIRLPSVPSNEVGTSKP-KAEKGKTKDKELEELQNWA 1216
            AALQAL RKKRYEKQL Q+DG ++TIEFQ EA+ENA TNTE+LK M  A+ A+KS+H+NMDI+KV+D+M DITEQQELA+EI+D+IS PVGFG ++D+DEL+AEL+ L++E L + L ++   +++ LP+VPS    TS P +  + +  + ++E+LQ WA
Sbjct:   91 AALQALKRKKRYEKQLAQIDGTISTIEFQREALENANTNTEVLKNMGLAAKAMKSAHENMDINKVDDLMQDITEQQELAQEISDAISKPVGFGEEFDEDELLAELDELEQEELDKNLLEIGGPENVPLPNVPS----TSLPSRPARKEEDEDDMEDLQRWA 247
[Close]
BLAST of Charged multivesicular body protein 4b vs. Planmine SMEST
Match: SMESG000042643.1 (SMESG000042643.1)

HSP 1 Score: 366.311 bits (939), Expect = 2.006e-126
Identity = 216/217 (99.54%), Postives = 217/217 (100.00%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVNEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIAD+ISNPVGFGHDYDDDELMAELELLQEENLKEKLTKVNEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS
Sbjct:    1 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADAISNPVGFGHDYDDDELMAELELLQEENLKEKLTKVNEDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 217
[Close]
BLAST of Charged multivesicular body protein 4b vs. Planmine SMEST
Match: SMESG000008139.1 (SMESG000008139.1)

HSP 1 Score: 241.891 bits (616), Expect = 1.295e-77
Identity = 136/223 (60.99%), Postives = 177/223 (79.37%), Query Frame = 2 
Query:  569 MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKRHGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEILKAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFGHDYDDDXXXXXXXXXXXXXXXXXXXXVN------EDDIRLPSVPSNEVGTSKPKAEKGKTKDKELEELQNWAS 1219
            +  FFG+KK +   SP +A++KLK +++ML KKQ FLEKKIE E+ TAK+HG KNKRAALQAL RKKRYEKQL Q+DG LTT+EFQ+EA+ENA+TNTE+LKAM+ AS +LKS+HQ+MD+DKV+D+MD+I EQQELAKEIAD++SNPVGFGHDYD+DEL+ ELE LQEE+L+  L  V+      +  I LPS P  E+  ++PK  K + ++ EL +L+ WAS
Sbjct:    3 LGAFFGRKKKETGESPQDAIQKLKGIQDMLLKKQDFLEKKIEQELITAKKHGTKNKRAALQALARKKRYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKSAHQHMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHDYDEDELLRELESLQEEDLESALLDVSGRTANTDPTIGLPSAPQGEL--TRPK--KNRKEEDELADLEAWAS 221
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BLAST of Charged multivesicular body protein 4b vs. Planmine SMEST
Match: SMESG000042754.1 (SMESG000042754.1)

HSP 1 Score: 65.0846 bits (157), Expect = 3.228e-13
Identity = 31/32 (96.88%), Postives = 31/32 (96.88%), Query Frame = -3 
Query: 1301 LSFGQGIYVSGTLIHLNNDIYIRAVDLFTIKR 1396
            LSFGQ IYVSGTLIHLNNDIYIRAVDLFTIKR
Sbjct:   44 LSFGQDIYVSGTLIHLNNDIYIRAVDLFTIKR 75
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BLAST of Charged multivesicular body protein 4b vs. Planmine SMEST
Match: SMESG000078154.1 (SMESG000078154.1)

HSP 1 Score: 56.9954 bits (136), Expect = 1.642e-8
Identity = 30/45 (66.67%), Postives = 38/45 (84.44%), Query Frame = -2 
Query:  171 VQTIVDSEMSEEDIV*DISSNEVSEDRVKEVLLTKSSIEMELVIS 305
            V+T+ +S MSEEDIV DI +N+V +DRVKE+LLTKSSI+ME V S
Sbjct:   71 VKTVFNSGMSEEDIVRDIIANKVRDDRVKEILLTKSSIQMEEVRS 115
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BLAST of Charged multivesicular body protein 4b vs. Planmine SMEST
Match: SMESG000058933.1 (SMESG000058933.1)

HSP 1 Score: 55.4546 bits (132), Expect = 3.890e-8
Identity = 32/53 (60.38%), Postives = 40/53 (75.47%), Query Frame = -2 
Query:  156 VQTIVDSEMSEEDIV*DISSNEVSEDRVKEVLLTKSSIEMELVISG---MENL 305
            V+T+ +S MSEEDIV DI +N+V +DRVKE+LLT SSI+ME V S     ENL
Sbjct:  117 VKTVFNSGMSEEDIVRDIIANKVRDDRVKEILLTNSSIQMEKVRSTDKIYENL 169
The following BLAST results are available for this feature:
BLAST of Charged multivesicular body protein 4b vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CHMP4B6.911e-6258.82charged multivesicular body protein 4B [Source:HGN... [more]
CHMP4A1.322e-5851.13charged multivesicular body protein 4A [Source:HGN... [more]
CHMP4A1.322e-5851.13charged multivesicular body protein 4A [Source:HGN... [more]
CHMP4A1.427e-5850.44charged multivesicular body protein 4A [Source:HGN... [more]
CHMP4A1.427e-5850.44charged multivesicular body protein 4A [Source:HGN... [more]
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BLAST of Charged multivesicular body protein 4b vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
vps-32.12.246e-5950.45Related to yeast Vacuolar Protein Sorting factor ... [more]
vps-32.12.246e-5950.45Related to yeast Vacuolar Protein Sorting factor ... [more]
R12C12.53.703e-3033.90pep chromosome:WBcel235:II:6044145:6045218:-1 gene... [more]
vps-203.540e-830.91Related to yeast Vacuolar Protein Sorting factor ... [more]
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BLAST of Charged multivesicular body protein 4b vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shrb9.650e-5458.64gene:FBgn0086656 transcript:FBtr0088623[more]
Vps201.087e-728.99gene:FBgn0034744 transcript:FBtr0071856[more]
Vps201.087e-728.99gene:FBgn0034744 transcript:FBtr0308602[more]
Vps601.166e-730.10gene:FBgn0036740 transcript:FBtr0333123[more]
Vps601.166e-730.10gene:FBgn0036740 transcript:FBtr0075201[more]
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BLAST of Charged multivesicular body protein 4b vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
chmp4ba1.065e-5957.43charged multivesicular body protein 4Ba [Source:NC... [more]
chmp4bb2.100e-5958.54charged multivesicular body protein 4Bb [Source:NC... [more]
chmp4c8.569e-5150.24charged multivesicular body protein 4C [Source:ZFI... [more]
chmp4c8.569e-5150.24charged multivesicular body protein 4C [Source:ZFI... [more]
chmp4bb1.058e-756.82charged multivesicular body protein 4Bb [Source:NC... [more]
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BLAST of Charged multivesicular body protein 4b vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
fmn13.433e-6457.99formin 1 [Source:Xenbase;Acc:XB-GENE-940125][more]
CHMP4C3.815e-5552.86charged multivesicular body protein 4C [Source:NCB... [more]
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BLAST of Charged multivesicular body protein 4b vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Chmp4b4.219e-6258.82charged multivesicular body protein 4B [Source:MGI... [more]
Chmp4c7.766e-4851.57charged multivesicular body protein 4C [Source:MGI... [more]
Chmp4c3.817e-841.94charged multivesicular body protein 4C [Source:MGI... [more]
Chmp61.084e-724.77charged multivesicular body protein 6 [Source:MGI ... [more]
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BLAST of Charged multivesicular body protein 4b vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6GL11|CHM4B_XENTR1.983e-6458.45Charged multivesicular body protein 4b OS=Xenopus ... [more]
sp|Q5XGW6|CHM4B_XENLA2.735e-6457.99Charged multivesicular body protein 4b OS=Xenopus ... [more]
sp|Q9D8B3|CHM4B_MOUSE2.951e-6158.82Charged multivesicular body protein 4b OS=Mus musc... [more]
sp|Q9H444|CHM4B_HUMAN3.319e-6158.82Charged multivesicular body protein 4b OS=Homo sap... [more]
sp|A2VDY3|CHM4A_BOVIN1.503e-5952.49Charged multivesicular body protein 4a OS=Bos taur... [more]
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BLAST of Charged multivesicular body protein 4b vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2I4BWS67.750e-6458.33charged multivesicular body protein 4b OS=Austrofu... [more]
A0A3P8X1E71.428e-6359.53Uncharacterized protein OS=Cynoglossus semilaevis ... [more]
A0A433TYK31.887e-6356.74Uncharacterized protein OS=Elysia chlorotica OX=18... [more]
A0A401T7E93.401e-6356.62Uncharacterized protein OS=Chiloscyllium punctatum... [more]
V4C9765.513e-6355.30Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
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BLAST of Charged multivesicular body protein 4b vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
chmp4bb4.172e-6159.11charged multivesicular body protein 4c [Source:NCB... [more]
ENSAMXT00000057406.11.456e-5954.79charged multivesicular body protein 4b [Source:NCB... [more]
chmp4c5.745e-3244.17charged multivesicular body protein 4C [Source:ZFI... [more]
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BLAST of Charged multivesicular body protein 4b vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000006536.13.806e-3969.79pep scaffold:Pmarinus_7.0:GL484585:4905:9162:1 gen... [more]
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BLAST of Charged multivesicular body protein 4b vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
SNF72.277e-2231.92One of four subunits of the ESCRT-III complex; inv... [more]
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BLAST of Charged multivesicular body protein 4b vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO472811.433e-5253.42Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO427792.509e-3449.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO479723.513e-930.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO490151.451e-830.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Charged multivesicular body protein 4b vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000016086.21.495e-6259.02charged multivesicular body protein 4b [Source:NCB... [more]
chmp4bb4.385e-5957.14charged multivesicular body protein 4B [Source:NCB... [more]
chmp4c6.226e-5164.18charged multivesicular body protein 4c [Source:NCB... [more]
chmp4c6.226e-5164.18charged multivesicular body protein 4c [Source:NCB... [more]
chmp4bb1.772e-3956.52charged multivesicular body protein 4B [Source:NCB... [more]
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BLAST of Charged multivesicular body protein 4b vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000042643.12.006e-12699.54SMESG000042643.1[more]
SMESG000008139.11.295e-7760.99SMESG000008139.1[more]
SMESG000042754.13.228e-1396.88SMESG000042754.1[more]
SMESG000078154.11.642e-866.67SMESG000078154.1[more]
SMESG000058933.13.890e-860.38SMESG000058933.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022189 ID=SMED30022189|Name=Charged multivesicular body protein 4b|organism=Schmidtea mediterranea sexual|type=transcript|length=1398bp
AACTGAATAATGAGTGAATTATAATAATGTTGCATTTAAAAAATTATTTT
TATTTTTTGTACTAGTACTAGAATAAGCTGGTAATATATTCCACGGAAAA
CAATAAGCTTATATGTATACTATTTTCGAAATTTAAATTGGCTTTCCAAG
GTGAAAAGGTTCTCCATCCCTGATATAACTAATTCCATTTCTATGCTTGA
TTTTGTCAATAGAACTTCTTTAACTCGATCCTCCGATACTTCATTGGAAC
TAATATCTCAGACAATGTCTTCTTCGCTCATTTCTGAATCAACTATGGTT
TGAACAGATTTCGGAGTCAAATGTTAAAATTCAGACATTTTGTCTTTTTT
TTAATTTTAAGCATTCATCACCATTGTCATTACAATTTCAATTCTCAAAT
AAAAGTCTTAATCTCAAACTGTAGTGTATAAATTAATTTAGTGAACTACA
ATAAAATAGAATCGTAGAGATTTAAATTACCATTTGTTTGTATAAATCAT
TTTCTTTAAATTAAAGTCATTTTCGAATTTATATAATGAATTTATATTAA
TATTTGTTCTTTAATGAAATGAATAAATTTTTCGGGAAGAAGAAGGACGA
TAAAGAATCTTCACCGGTAGAAGCACTTAGAAAGTTAAAAGATGTTAAAG
AAATGCTTGATAAAAAACAAATGTTTTTGGAAAAGAAAATTGAAAACGAA
ATTGAAACGGCAAAGCGTCATGGAATGAAAAATAAAAGAGCTGCATTGCA
AGCATTAGGAAGAAAAAAACGATACGAAAAACAACTTCAGCAAATGGATG
GAATACTAACAACAATAGAATTTCAAATTGAAGCTGTTGAAAATGCGACA
ACAAACACAGAAATTCTTAAAGCAATGAAACAAGCTTCTGTTGCATTGAA
ATCCTCGCATCAAAATATGGATATTGATAAAGTTAATGATATAATGGATG
ATATTACTGAGCAGCAGGAATTGGCTAAAGAAATAGCTGATTCTATATCA
AATCCTGTCGGATTTGGTCATGATTATGATGATGATGAATTAATGGCCGA
GTTAGAATTGCTTCAAGAAGAGAATTTAAAAGAAAAACTTACAAAAGTAA
ACGAGGATGATATTAGACTACCTTCTGTACCCTCTAATGAAGTAGGAACT
TCAAAACCAAAAGCTGAAAAAGGTAAAACCAAAGACAAAGAACTGGAAGA
ATTACAGAACTGGGCATCGTGATATACTAACAATGAAAAAGTATCGCTTT
TATCTTATTAAGATACAAGATAAATCTATAAAAAACGCATGATTTATTTA
TCTCTTAATTGTAAACAGATCTACTGCACGTATATAAATATCATTATTCA
AATGTATTAAAGTGCCAGAGACATATATACCTTGTCCGAAAGATAGAG
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protein sequence of SMED30022189-orf-1

>SMED30022189-orf-1 ID=SMED30022189-orf-1|Name=SMED30022189-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=218bp
MNKFFGKKKDDKESSPVEALRKLKDVKEMLDKKQMFLEKKIENEIETAKR
HGMKNKRAALQALGRKKRYEKQLQQMDGILTTIEFQIEAVENATTNTEIL
KAMKQASVALKSSHQNMDIDKVNDIMDDITEQQELAKEIADSISNPVGFG
HDYDDDELMAELELLQEENLKEKLTKVNEDDIRLPSVPSNEVGTSKPKAE
KGKTKDKELEELQNWAS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR005024Snf7_fam
Vocabulary: biological process
TermDefinition
GO:0007034vacuolar transport
GO:0015031protein transport
GO:0031468nuclear envelope reassembly
GO:0090148membrane fission
GO:0000281mitotic cytokinesis
GO:0006810transport
GO:0010458exit from mitosis
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0030496midbody
GO:0031902late endosome membrane
GO:0000815ESCRT III complex
GO:0005635nuclear envelope
GO:0005737cytoplasm
GO:0005768endosome
GO:0005829cytosol
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 20..40
NoneNo IPR availableGENE3DG3DSA:1.10.287.1060coord: 14..91
e-value: 8.7E-30
score: 104.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 176..217
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 196..217
NoneNo IPR availablePANTHERPTHR22761SNF7 - RELATEDcoord: 6..216
NoneNo IPR availablePANTHERPTHR22761:SF4CHARGED MULTIVESICULAR BODY PROTEIN 4Bcoord: 6..216
IPR005024Snf7 familyPFAMPF03357Snf7coord: 18..191
e-value: 2.2E-45
score: 154.3