Epithelial splicing regulatory protein 1/2

Overview
NameEpithelial splicing regulatory protein 1/2
Smed IDSMED30022187
Length (bp)3215
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Epithelial splicing regulatory protein 1/2 (SMED30022187) t-SNE clustered cells

Violin plots show distribution of expression levels for Epithelial splicing regulatory protein 1/2 (SMED30022187) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Epithelial splicing regulatory protein 1/2 (SMED30022187) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Epithelial splicing regulatory protein 1/2 (SMED30022187) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30022187

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30022187h1SMcG0022083 dd_Smed_v4_5053_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30022187h1SMcG0022083 dd_Smed_v4_5053_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30022187h1SMcG0022083 dd_Smed_v4_5053_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30022187h1SMcG0022083 dd_Smed_v4_5053_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30022187h1SMcG0022083 dd_Smed_v4_5053_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30022187h1SMcG0022083 dd_Smed_v4_5053_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Match: ESRP1 (epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966])

HSP 1 Score: 376.711 bits (966), Expect = 1.734e-117
Identity = 218/565 (38.58%), Postives = 316/565 (55.93%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSG 2298
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   + S   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H++ +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS 
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHVRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNM-----KDRYVEVFQCSA 525          

HSP 2 Score: 111.694 bits (278), Expect = 1.349e-24
Identity = 80/257 (31.13%), Postives = 124/257 (48.25%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSP 2013
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++N+ +RY+E+F+ +  E+N V+                      T+N N +S  P ++P ++ P
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGG-------------------TLNRNGLSPPPCKLPCLSPP 555          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Match: ESRP1 (epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966])

HSP 1 Score: 375.941 bits (964), Expect = 3.208e-117
Identity = 218/565 (38.58%), Postives = 316/565 (55.93%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSG 2298
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   + S   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H++ +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS 
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHVRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNM-----KDRYVEVFQCSA 525          

HSP 2 Score: 109.768 bits (273), Expect = 5.410e-24
Identity = 73/215 (33.95%), Postives = 111/215 (51.63%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++N+ +RY+E+F+ +  E+N V+
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVL 532          

HSP 3 Score: 56.9954 bits (136), Expect = 1.727e-7
Identity = 34/90 (37.78%), Postives = 50/90 (55.56%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFR--GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            +R RGLP+ AT  DI  F      +I   G+ +VL+  GR +G+A I+ KS +   MA +K HK +M  RY+EV+  +  +   V  G T
Sbjct:  447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGT 536          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Match: ESRP1 (epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966])

HSP 1 Score: 377.481 bits (968), Expect = 6.294e-117
Identity = 218/568 (38.38%), Postives = 318/568 (55.99%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   + S   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H++ +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS  ++
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHVRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNM-----KDRYVEVFQCSAEEM 528          

HSP 2 Score: 112.464 bits (280), Expect = 1.217e-24
Identity = 80/257 (31.13%), Postives = 124/257 (48.25%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFR---GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSP 2013
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++N+ +RY+E+F+ +  E+N V+                      T+N N +S  P ++P ++ P
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGG-------------------TLNRNGLSPPPCKLPCLSPP 555          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Match: ESRP1 (epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966])

HSP 1 Score: 376.326 bits (965), Expect = 1.033e-116
Identity = 218/568 (38.38%), Postives = 318/568 (55.99%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   + S   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H++ +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS  ++
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHVRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNM-----KDRYVEVFQCSAEEM 528          

HSP 2 Score: 110.153 bits (274), Expect = 4.704e-24
Identity = 73/215 (33.95%), Postives = 111/215 (51.63%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++N+ +RY+E+F+ +  E+N V+
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVL 532          

HSP 3 Score: 56.9954 bits (136), Expect = 1.609e-7
Identity = 34/90 (37.78%), Postives = 50/90 (55.56%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFR--GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            +R RGLP+ AT  DI  F      +I   G+ +VL+  GR +G+A I+ KS +   MA +K HK +M  RY+EV+  +  +   V  G T
Sbjct:  447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGT 536          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Match: ESRP1 (epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:HGNC:25966])

HSP 1 Score: 376.326 bits (965), Expect = 1.614e-116
Identity = 218/568 (38.38%), Postives = 318/568 (55.99%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   + S   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H++ +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS  ++
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHVRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNM-----KDRYVEVFQCSAEEM 528          

HSP 2 Score: 110.538 bits (275), Expect = 4.882e-24
Identity = 73/215 (33.95%), Postives = 111/215 (51.63%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++N+ +RY+E+F+ +  E+N V+
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVL 532          

HSP 3 Score: 57.3806 bits (137), Expect = 1.563e-7
Identity = 34/90 (37.78%), Postives = 50/90 (55.56%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFR--GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            +R RGLP+ AT  DI  F      +I   G+ +VL+  GR +G+A I+ KS +   MA +K HK +M  RY+EV+  +  +   V  G T
Sbjct:  447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGT 536          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Match: sym-2 (RNA-binding protein sym-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22708])

HSP 1 Score: 256.914 bits (655), Expect = 8.832e-74
Identity = 166/454 (36.56%), Postives = 239/454 (52.64%), Query Frame = 1
Query:  961 LVTDGQAPMRLAFHPEIARNNIDLTN--YDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVS---DEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            + T G  P+R    P  ARN + + +  + YY    D++  +  + N+E+  +  E I++             +     +L++     DD    K  + V   Y  A + +   V    D VV RARGLPWQA+D  + +FF GL+I  GGIAL LS  GRRNGE L++F S+E RD+AL++H++ +  RYIEVY A   +F+ VA G + EA  F+      +  ++RMRGLPY  T  QI  FF     P++   D ILF+   DGR TGDAFV FE EE A++ L  HR+ IG RYIELFKST AEV QV+                          NLI+  P     + +P   +    +  VR++G+P E TV  I+ FL  +   + +QG H++YN+ G P+GEA IQMI+EQAA+      H   +S+   KK  ++V   S  ++
Sbjct:   83 IFTKGPEPIRHVLIPLFARNELCVPHPLHHYY----DIKHLY--YGNQEEDGMEQEEIED------------DVAIARAILDM-----DDELLEKTHQFVNIEYQPAPILEDQEVGADGDNVVCRARGLPWQASDHHVAQFFAGLDIVPGGIALCLSSEGRRNGEVLVQFSSQESRDLALKRHRNFLLSRYIEVYKAGLDEFMHVATGSSTEAMEFV----SANAIIVRMRGLPYDCTDAQIRTFFE----PLKL-TDKILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRC-----------------------NLINSSPAVANAVEAPEEKK----KDCVRLRGLPYEATVQHIVTFLGDFATMVKFQGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSVGK-KKRYIEVFQASAEEL 476          

HSP 2 Score: 98.9821 bits (245), Expect = 5.840e-21
Identity = 60/203 (29.56%), Postives = 99/203 (48.77%), Query Frame = 1
Query: 1300 SDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAG-----GDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENI-----GNRYIELFKSTPAEVN 1878
            ++ ++VR RGLP+  TD+ I  FF  L +    I  +    GR  G+A ++F++ E     L KH+  +GQRYIE++ +T  +  QV         +      ++   +  +  +R+RGLPY AT   I+ F       V+F   G+  V +  G  +G+AF+   NE+ A         N        RYIE+F+++  E+N
Sbjct:  278 ANAIIVRMRGLPYDCTDAQIRTFFEPLKL-TDKILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEEKKKDCVRLRGLPYEATVQHIVTFLGDFATMVKF--QGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSVGKKKRYIEVFQASAEELN 477          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Match: sym-2 (RNA-binding protein sym-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22708])

HSP 1 Score: 151.754 bits (382), Expect = 6.623e-40
Identity = 89/228 (39.04%), Postives = 122/228 (53.51%), Query Frame = 1
Query: 1624 LIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            ++RMRGLPY  T  QI  FF     P++   D ILF+   DGR TGDAFV FE EE A++ L  HR+ IG RYIELFKST AEV QV+                          NLI+  P     + +P   +    +  VR++G+P E TV  I+ FL  +   + +QG H++YN+ G P+GEA IQMI+EQAA+      H   +S+   KK  ++V   S  ++
Sbjct:   10 IVRMRGLPYDCTDAQIRTFFE----PLKL-TDKILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRC-----------------------NLINSSPAVANAVEAPEEKK----KDCVRLRGLPYEATVQHIVTFLGDFATMVKFQGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSVGK-KKRYIEVFQASAEEL 204          

HSP 2 Score: 100.523 bits (249), Expect = 2.026e-22
Identity = 62/207 (29.95%), Postives = 102/207 (49.28%), Query Frame = 1
Query: 1291 DYVS-DEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAG-----GDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENI-----GNRYIELFKSTPAEVN 1878
            ++VS + ++VR RGLP+  TD+ I  FF  L +    I  +    GR  G+A ++F++ E     L KH+  +GQRYIE++ +T  +  QV         +      ++   +  +  +R+RGLPY AT   I+ F       V+F   G+  V +  G  +G+AF+   NE+ A         N        RYIE+F+++  E+N
Sbjct:    2 EFVSANAIIVRMRGLPYDCTDAQIRTFFEPLKLTDK-ILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEEKKKDCVRLRGLPYEATVQHIVTFLGDFATMVKF--QGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSVGKKKRYIEVFQASAEELN 205          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Match: sym-2 (RNA-binding protein sym-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22708])

HSP 1 Score: 151.754 bits (382), Expect = 6.623e-40
Identity = 89/228 (39.04%), Postives = 122/228 (53.51%), Query Frame = 1
Query: 1624 LIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            ++RMRGLPY  T  QI  FF     P++   D ILF+   DGR TGDAFV FE EE A++ L  HR+ IG RYIELFKST AEV QV+                          NLI+  P     + +P   +    +  VR++G+P E TV  I+ FL  +   + +QG H++YN+ G P+GEA IQMI+EQAA+      H   +S+   KK  ++V   S  ++
Sbjct:   10 IVRMRGLPYDCTDAQIRTFFE----PLKL-TDKILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRC-----------------------NLINSSPAVANAVEAPEEKK----KDCVRLRGLPYEATVQHIVTFLGDFATMVKFQGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSVGK-KKRYIEVFQASAEEL 204          

HSP 2 Score: 100.523 bits (249), Expect = 2.026e-22
Identity = 62/207 (29.95%), Postives = 102/207 (49.28%), Query Frame = 1
Query: 1291 DYVS-DEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAG-----GDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENI-----GNRYIELFKSTPAEVN 1878
            ++VS + ++VR RGLP+  TD+ I  FF  L +    I  +    GR  G+A ++F++ E     L KH+  +GQRYIE++ +T  +  QV         +      ++   +  +  +R+RGLPY AT   I+ F       V+F   G+  V +  G  +G+AF+   NE+ A         N        RYIE+F+++  E+N
Sbjct:    2 EFVSANAIIVRMRGLPYDCTDAQIRTFFEPLKLTDK-ILFITRTDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEVQQVVKRCNLINSSPAVANAVEAPEEKKKDCVRLRGLPYEATVQHIVTFLGDFATMVKF--QGVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSVGKKKRYIEVFQASAEELN 205          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Match: hrpf-1 (HnRNP F homolog [Source:UniProtKB/TrEMBL;Acc:H2KZN0])

HSP 1 Score: 110.153 bits (274), Expect = 1.519e-25
Identity = 66/200 (33.00%), Postives = 106/200 (53.00%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATG---RDFIQVAGGDTEEAEVFLQRITKP--------------SQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKST 1863
            V+ RGLPW+AT+ ++  FF    IE      +  + GR +G+A + F + E  + AL+K + H+G RYIEV+ A G   R   +   GD  + + +  R   P                +++R+RGLP++ T+  I +F      P+    DGIL  + +  R  G+A+V FE  E  + A + H +NIG+RYIE+F++T
Sbjct:    7 VQCRGLPWEATEQELRDFFGNNGIES---LEIPRRNGRTSGDAKVVFTNEEDYNNALKKDREHLGSRYIEVFPAGGAPTRRGDRGERGDRGDRDHYRSRGAPPRDRYSDRGGPRSSGPDSIVRLRGLPFSVTSRDISDFL----APLPIVRDGILLPDQQRARPGGEAYVCFETMESVQIAKQRHMKNIGHRYIEVFEAT 199          

HSP 2 Score: 65.0846 bits (157), Expect = 9.155e-11
Identity = 49/145 (33.79%), Postives = 69/145 (47.59%), Query Frame = 1
Query: 1261 HYYSAIVRKSDYVSD---------EVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKP-----SQTLIRMRGLPYT 1653
            HY S      D  SD         + +VR RGLP+  T  DI+ F   L I + GI L   +  R  GEA + F++ E   +A ++H  ++G RYIEV+ AT RD  + A    EE ++ + R   P      QT  R    PY+
Sbjct:   98 HYRSRGAPPRDRYSDRGGPRSSGPDSIVRLRGLPFSVTSRDISDFLAPLPIVRDGILLPDQQRARPGGEAYVCFETMESVQIAKQRHMKNIGHRYIEVFEATHRDLSRFA----EENDLRVPRFGPPPFASAPQTAPRGAYDPYS 238          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Match: hrpf-1 (HnRNP F homolog [Source:UniProtKB/TrEMBL;Acc:H2KZN0])

HSP 1 Score: 108.997 bits (271), Expect = 2.546e-24
Identity = 66/200 (33.00%), Postives = 106/200 (53.00%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATG---RDFIQVAGGDTEEAEVFLQRITKP--------------SQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKST 1863
            V+ RGLPW+AT+ ++  FF    IE      +  + GR +G+A + F + E  + AL+K + H+G RYIEV+ A G   R   +   GD  + + +  R   P                +++R+RGLP++ T+  I +F      P+    DGIL  + +  R  G+A+V FE  E  + A + H +NIG+RYIE+F++T
Sbjct:    7 VQCRGLPWEATEQELRDFFGNNGIES---LEIPRRNGRTSGDAKVVFTNEEDYNNALKKDREHLGSRYIEVFPAGGAPTRRGDRGERGDRGDRDHYRSRGAPPRDRYSDRGGPRSSGPDSIVRLRGLPFSVTSRDISDFL----APLPIVRDGILLPDQQRARPGGEAYVCFETMESVQIAKQRHMKNIGHRYIEVFEAT 199          

HSP 2 Score: 64.3142 bits (155), Expect = 3.168e-10
Identity = 49/145 (33.79%), Postives = 69/145 (47.59%), Query Frame = 1
Query: 1261 HYYSAIVRKSDYVSD---------EVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKP-----SQTLIRMRGLPYT 1653
            HY S      D  SD         + +VR RGLP+  T  DI+ F   L I + GI L   +  R  GEA + F++ E   +A ++H  ++G RYIEV+ AT RD  + A    EE ++ + R   P      QT  R    PY+
Sbjct:   98 HYRSRGAPPRDRYSDRGGPRSSGPDSIVRLRGLPFSVTSRDISDFLAPLPIVRDGILLPDQQRARPGGEAYVCFETMESVQIAKQRHMKNIGHRYIEVFEATHRDLSRFA----EENDLRVPRFGPPPFASAPQTAPRGAYDPYS 238          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Match: fus (gene:FBgn0023441 transcript:FBtr0302330)

HSP 1 Score: 374.4 bits (960), Expect = 4.071e-114
Identity = 238/620 (38.39%), Postives = 342/620 (55.16%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQ-------YQVSGR-------HESMTEEEKNQNRLLTEDC---CLETNLN-DSLFTGAQ-------------PLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE--KSLV-------------------LDEMIQECNIF-INDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTN---CPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQ--LNLGRT--FVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKK-SMVDVSACSGLDI 2307
            +V  +I T G+    LG+DE  I+L+   + +    + +  +Q       Y +  R       + S+T    +   L   D       T+ N +SL  G++             PLS  +++    L S+   S+   +  LVTDGQ P+R   H E +  +++L  Y  Y  F DLRKEF R+ + +  ++LV                   + EM+ E NI  + D+  ++ I +   M+ +I+ +   G K+   E V       I    D V    +VRARGLPWQ++D DI KFFRGLN+ KGG+AL LS +GRRNGEALIRF  +EHRDMAL++HKHH+G RYIEVY A+G DF+ +AGG + EA+ FL   +K +Q +IRMRGLPY ATA Q+L+FFT+ +   C V  G +G+LFV   DGRATGDAFV+F NE  A +AL  HRE+IG RYIELF+ST AEV QV+N  + P                +  G+    L  Q+P +  P L Q  +  G T   +R++G+P E  V  I++FL+ + ++I YQG H++ N+ GQP+GEA IQM  E++A L  + +H   +    GKK   ++V  CSG D+
Sbjct:    7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSL---SLHDTEIKLVTDGQLPLRQCLHREASAKDVELPAY--YNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDN--DFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHIGTRYIEVYRASGEDFLAIAGGASNEAQAFL---SKGAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVLNRSMDPKNYE------------SGGGHSQPPLIAQLPTMQLPLLPQHLITSGTTKNCIRLRGLPYEAMVEHILHFLDDFAKHIIYQGVHMVINAQGQPSGEAFIQMDLEESARLCAQRRHNHYMMF--GKKYRYIEVFQCSGDDM 602          

HSP 2 Score: 83.1889 bits (204), Expect = 8.004e-16
Identity = 72/282 (25.53%), Postives = 124/282 (43.97%), Query Frame = 1
Query: 1174 IIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSD-----YVSD--EVVVRARGLPWQATDSDINKFFRG-----LNIEKG--GIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV-----------AGGDTEEAEVFLQRIT-------------KPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAE---EALKSHRENIGN--RYIELFKSTPAEVNQVMN 1890
            + Q H+ + + R     G ++ E    +   + AI   +      ++S   +V++R RGLP+ AT   +  FF        ++  G  G+  V    GR  G+A + F +      AL +H+  +GQRYIE++ +T  +  QV           +GG   +  +  Q  T               ++  IR+RGLPY A    IL F       + +   G+  V +  G+ +G+AF+  + EE A    +   +H    G   RYIE+F+ +  ++N V+N
Sbjct:  328 VCQEHRDMALKRHKHHIGTRYIEVYRASGEDFLAIAGGASNEAQAFLSKGAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVLNRSMDPKNYESGGGHSQPPLIAQLPTMQLPLLPQHLITSGTTKNCIRLRGLPYEAMVEHILHFLDDFAKHIIY--QGVHMVINAQGQPSGEAFIQMDLEESARLCAQRRHNHYMMFGKKYRYIEVFQCSGDDMNMVLN 607          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Match: fus (gene:FBgn0023441 transcript:FBtr0087345)

HSP 1 Score: 364.77 bits (935), Expect = 3.447e-110
Identity = 238/651 (36.56%), Postives = 344/651 (52.84%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQ-------YQVSGR-------HESMTEEEKNQNRLLTEDC---CLETNLN-DSLFTGAQ-------------PLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE--KSLV-------------------LDEMIQECNIF-INDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTN---CPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQL-------NLG----------------------------RTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKK-SMVDVSACSGLDI 2307
            +V  +I T G+    LG+DE  I+L+   + +    + +  +Q       Y +  R       + S+T    +   L   D       T+ N +SL  G++             PLS  +++    L S+   S+   +  LVTDGQ P+R   H E +  +++L  Y  Y  F DLRKEF R+ + +  ++LV                   + EM+ E NI  + D+  ++ I +   M+ +I+ +   G K+   E V       I    D V    +VRARGLPWQ++D DI KFFRGLN+ KGG+AL LS +GRRNGEALIRF  +EHRDMAL++HKHH+G RYIEVY A+G DF+ +AGG + EA+ FL   +K +Q +IRMRGLPY ATA Q+L+FFT+ +   C V  G +G+LFV   DGRATGDAFV+F NE  A +AL  HRE+IG RYIELF+ST AEV QV+N  + P                +  G+    L  Q+P +  P L Q+       +LG                            +  +R++G+P E  V  I++FL+ + ++I YQG H++ N+ GQP+GEA IQM  E++A L  + +H   +    GKK   ++V  CSG D+
Sbjct:    7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSL---SLHDTEIKLVTDGQLPLRQCLHREASAKDVELPAY--YNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDN--DFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHIGTRYIEVYRASGEDFLAIAGGASNEAQAFL---SKGAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVLNRSMDPKNYE------------SGGGHSQPPLIAQLPTMQLPLLPQVGAHSLSHSLGASPANLCPPVPPPALPLPTQHLITSGTTKNCIRLRGLPYEAMVEHILHFLDDFAKHIIYQGVHMVINAQGQPSGEAFIQMDLEESARLCAQRRHNHYMMF--GKKYRYIEVFQCSGDDM 633          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Match: fus (gene:FBgn0023441 transcript:FBtr0087343)

HSP 1 Score: 364.77 bits (935), Expect = 1.849e-109
Identity = 238/651 (36.56%), Postives = 344/651 (52.84%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQ-------YQVSGR-------HESMTEEEKNQNRLLTEDC---CLETNLN-DSLFTGAQ-------------PLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE--KSLV-------------------LDEMIQECNIF-INDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTN---CPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQL-------NLG----------------------------RTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKK-SMVDVSACSGLDI 2307
            +V  +I T G+    LG+DE  I+L+   + +    + +  +Q       Y +  R       + S+T    +   L   D       T+ N +SL  G++             PLS  +++    L S+   S+   +  LVTDGQ P+R   H E +  +++L  Y  Y  F DLRKEF R+ + +  ++LV                   + EM+ E NI  + D+  ++ I +   M+ +I+ +   G K+   E V       I    D V    +VRARGLPWQ++D DI KFFRGLN+ KGG+AL LS +GRRNGEALIRF  +EHRDMAL++HKHH+G RYIEVY A+G DF+ +AGG + EA+ FL   +K +Q +IRMRGLPY ATA Q+L+FFT+ +   C V  G +G+LFV   DGRATGDAFV+F NE  A +AL  HRE+IG RYIELF+ST AEV QV+N  + P                +  G+    L  Q+P +  P L Q+       +LG                            +  +R++G+P E  V  I++FL+ + ++I YQG H++ N+ GQP+GEA IQM  E++A L  + +H   +    GKK   ++V  CSG D+
Sbjct:    7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSL---SLHDTEIKLVTDGQLPLRQCLHREASAKDVELPAY--YNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDN--DFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHIGTRYIEVYRASGEDFLAIAGGASNEAQAFL---SKGAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVLNRSMDPKNYE------------SGGGHSQPPLIAQLPTMQLPLLPQVGAHSLSHSLGASPANLCPPVPPPALPLPTQHLITSGTTKNCIRLRGLPYEAMVEHILHFLDDFAKHIIYQGVHMVINAQGQPSGEAFIQMDLEESARLCAQRRHNHYMMF--GKKYRYIEVFQCSGDDM 633          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Match: fus (gene:FBgn0023441 transcript:FBtr0087344)

HSP 1 Score: 364.77 bits (935), Expect = 1.849e-109
Identity = 238/651 (36.56%), Postives = 344/651 (52.84%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQ-------YQVSGR-------HESMTEEEKNQNRLLTEDC---CLETNLN-DSLFTGAQ-------------PLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE--KSLV-------------------LDEMIQECNIF-INDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTN---CPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQL-------NLG----------------------------RTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKK-SMVDVSACSGLDI 2307
            +V  +I T G+    LG+DE  I+L+   + +    + +  +Q       Y +  R       + S+T    +   L   D       T+ N +SL  G++             PLS  +++    L S+   S+   +  LVTDGQ P+R   H E +  +++L  Y  Y  F DLRKEF R+ + +  ++LV                   + EM+ E NI  + D+  ++ I +   M+ +I+ +   G K+   E V       I    D V    +VRARGLPWQ++D DI KFFRGLN+ KGG+AL LS +GRRNGEALIRF  +EHRDMAL++HKHH+G RYIEVY A+G DF+ +AGG + EA+ FL   +K +Q +IRMRGLPY ATA Q+L+FFT+ +   C V  G +G+LFV   DGRATGDAFV+F NE  A +AL  HRE+IG RYIELF+ST AEV QV+N  + P                +  G+    L  Q+P +  P L Q+       +LG                            +  +R++G+P E  V  I++FL+ + ++I YQG H++ N+ GQP+GEA IQM  E++A L  + +H   +    GKK   ++V  CSG D+
Sbjct:    7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSL---SLHDTEIKLVTDGQLPLRQCLHREASAKDVELPAY--YNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDN--DFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHIGTRYIEVYRASGEDFLAIAGGASNEAQAFL---SKGAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVLNRSMDPKNYE------------SGGGHSQPPLIAQLPTMQLPLLPQVGAHSLSHSLGASPANLCPPVPPPALPLPTQHLITSGTTKNCIRLRGLPYEAMVEHILHFLDDFAKHIIYQGVHMVINAQGQPSGEAFIQMDLEESARLCAQRRHNHYMMF--GKKYRYIEVFQCSGDDM 633          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Match: fus (gene:FBgn0023441 transcript:FBtr0087346)

HSP 1 Score: 364.77 bits (935), Expect = 1.849e-109
Identity = 238/651 (36.56%), Postives = 344/651 (52.84%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQ-------YQVSGR-------HESMTEEEKNQNRLLTEDC---CLETNLN-DSLFTGAQ-------------PLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE--KSLV-------------------LDEMIQECNIF-INDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTN---CPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQL-------NLG----------------------------RTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKK-SMVDVSACSGLDI 2307
            +V  +I T G+    LG+DE  I+L+   + +    + +  +Q       Y +  R       + S+T    +   L   D       T+ N +SL  G++             PLS  +++    L S+   S+   +  LVTDGQ P+R   H E +  +++L  Y  Y  F DLRKEF R+ + +  ++LV                   + EM+ E NI  + D+  ++ I +   M+ +I+ +   G K+   E V       I    D V    +VRARGLPWQ++D DI KFFRGLN+ KGG+AL LS +GRRNGEALIRF  +EHRDMAL++HKHH+G RYIEVY A+G DF+ +AGG + EA+ FL   +K +Q +IRMRGLPY ATA Q+L+FFT+ +   C V  G +G+LFV   DGRATGDAFV+F NE  A +AL  HRE+IG RYIELF+ST AEV QV+N  + P                +  G+    L  Q+P +  P L Q+       +LG                            +  +R++G+P E  V  I++FL+ + ++I YQG H++ N+ GQP+GEA IQM  E++A L  + +H   +    GKK   ++V  CSG D+
Sbjct:    7 VVSLYIATCGQNGSGLGSDEKEIILLVFVLLEVSTGQIVGTKQILVRPDGYFIKDRTISSSSDNSSVTNNTASSPPLAIGDANNGSGSTSGNGNSLENGSELILPIAEAQAAGKPLSEAIEEFDAYLRSL---SLHDTEIKLVTDGQLPLRQCLHREASAKDVELPAY--YNRFSDLRKEFLRYKSGDLARALVPVKDVKKMLQAPTLPMPQSIAEMLGELNISSVEDN--DFYIRESRDMVTVIQTLLQAGHKFAANELVNLVLEPGICSIDDEVDGNCIVRARGLPWQSSDQDIAKFFRGLNVAKGGVALCLSPLGRRNGEALIRFVCQEHRDMALKRHKHHIGTRYIEVYRASGEDFLAIAGGASNEAQAFL---SKGAQVIIRMRGLPYDATAKQVLDFFTTGDTPPCHVLDGNEGVLFVKKPDGRATGDAFVLFANETDAPKALGRHRESIGQRYIELFRSTTAEVQQVLNRSMDPKNYE------------SGGGHSQPPLIAQLPTMQLPLLPQVGAHSLSHSLGASPANLCPPVPPPALPLPTQHLITSGTTKNCIRLRGLPYEAMVEHILHFLDDFAKHIIYQGVHMVINAQGQPSGEAFIQMDLEESARLCAQRRHNHYMMF--GKKYRYIEVFQCSGDDM 633          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Match: esrp1 (epithelial splicing regulatory protein 1 [Source:NCBI gene;Acc:560190])

HSP 1 Score: 389.808 bits (1000), Expect = 2.359e-121
Identity = 225/569 (39.54%), Postives = 318/569 (55.89%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDG--FKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQI-----PMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LV+    T+G   D LG+DE  IV +   + D    K+ ++ +  V   H  ++EE           C   + L D   T   PL   +  L++ L +  + + +   F L TDGQ  +R   HPE +  NI L   D +F+F DLRKEF++ +  E   K L L  M    N+ ++ S   +   +  +M++I+  +  +    ++   E V + + +    K + V D  V+RARGLPWQ++D DI +FFRGLNI KGG AL L+  GRRNGEAL+RF+S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL R    +Q ++RMRGLP+ ATA Q+L+FF S  CPV  G +GILFV   DGR TGDAFV+F  EE A+ ALK H++ +G RYIELFKST AEV QV+N                       +  LI + P+ I     P    P    +   R  VR++G+P + ++ DI+ FL +YG  I   G H++ N  G+P+GEA IQM S + A L  +  HK+     S K+  V+V ACS  ++
Sbjct:    8 LVLLFTTTSGASGDKLGSDEKEIVQLVWQVVDLATKKAGQVNELLVKPDHIELSEE-----------CQELSGLTDEALTPVDPLEVAIDQLNQRLCA-EVDTGAGNTFYLCTDGQLHVRQVLHPEASSKNILLP--DCFFSFFDLRKEFKKEFPSEVKLKDLNLQVMADHLNVAVDSSLHAFTAYKVQQMVDIVLALISEPTCHEFTFPEKVNEKFETGTCSKMERVDDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFESEEHRDLALQRHKHHMGGRYIEVYKATGEDFLKIAGGTSNEVASFLSR---ENQIIVRMRGLPFNATAEQVLQFF-SPACPVTDGSEGILFVRFPDGRPTGDAFVLFSCEEHAQNALKKHKDMLGKRYIELFKSTAAEVQQVLNKYS--------------------SAPLIPVAPSPILSVVAPPTFVPQTAAVPGVRDCVRLRGLPYDASIQDILVFLGEYGADIKTHGVHMVLNHQGRPSGEAFIQMRSAERAFLAAQRCHKR-----SMKERYVEVFACSAQEV 533          

HSP 2 Score: 100.908 bits (250), Expect = 3.183e-21
Identity = 68/220 (30.91%), Postives = 108/220 (49.09%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFR-GLNIEKG--GIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEV------FLQRITKPS-----------QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++++VR RGLP+ AT   + +FF     +  G  GI  V    GR  G+A + F   EH   AL+KHK  +G+RYIE++ +T  +  QV    +    +       L  +  P+           +  +R+RGLPY A+   IL F        E+G D    G+  V +  GR +G+AF+   + E A   A + H+ ++  RY+E+F  +  EVN V+
Sbjct:  324 NQIIVRMRGLPFNATAEQVLQFFSPACPVTDGSEGILFVRFPDGRPTGDAFVLFSCEEHAQNALKKHKDMLGKRYIELFKSTAAEVQQVLNKYSSAPLIPVAPSPILSVVAPPTFVPQTAAVPGVRDCVRLRGLPYDASIQDILVFLG------EYGADIKTHGVHMVLNHQGRPSGEAFIQMRSAERAFLAAQRCHKRSMKERYVEVFACSAQEVNIVL 537          

HSP 3 Score: 59.3066 bits (142), Expect = 2.311e-8
Identity = 35/90 (38.89%), Postives = 52/90 (57.78%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMAL-RKHKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            VR RGLP+ A+  DI  F    G +I+  G+ +VL+  GR +GEA I+ +S E   +A  R HK  M +RY+EV+  + ++   V  G T
Sbjct:  452 VRLRGLPYDASIQDILVFLGEYGADIKTHGVHMVLNHQGRPSGEAFIQMRSAERAFLAAQRCHKRSMKERYVEVFACSAQEVNIVLMGGT 541          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:572992])

HSP 1 Score: 365.925 bits (938), Expect = 2.290e-112
Identity = 251/760 (33.03%), Postives = 374/760 (49.21%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLL------PNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIAQFSGFIQTPNQAQTQIQMQNALYQLQILQKQFVSSGIAINQ---VPYPSYWPCIPTSHXXXXXXXXXXXXXXXHILHSPLMGGYFYNIP-VPGQGPRMPAGLQTPSMVNPLNPCNNSYLQSP------LSH-SQPPGLVFSA-SNSPTTFYIPNMGVLQTHNNCQEYAFVVLKNLPKDITLEEIISIFE 2841
            LVVF   TAG     LG+DE  ++L+   I D  ++K  KL +  V      ++E+ K +  L  E+ C            A+PL  VL+  H+S +S  + S+ +  + L  DG   +R   HPE ++ N+ L   + ++ F+DL+KEF +        K L L  M+    I         G+ +   M+ +I  +  + +  K+   ETV   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF + EHRDMAL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT   +L F     CPV  G +G+LFV + DGR TGDAFV+F  EE A+ ALK H++ +G RYIELF+ST AEV QV+N                      M+  LIS L         +P++ +P        R  +R++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+++     K   V+V  CS  +++                               FV  G  +N+    P P   PC+      A             +   PL+       P  P   P       +P +   +N    +Y  SP      +S+ + PPG V +A +  PT   +P           Q  A V ++ LP +  +++I+S F+
Sbjct:    8 LVVFFGATAGANGGKLGSDERELILLVWQIVDLHENKVGKLHRTLVQPDSVDLSEQCKEETGLTAEELC-----------KAEPLESVLQQFHQS-VSAELKSLGRSSYTLCVDGPLLIRQVLHPEASKKNLVLP--ECFYTFVDLKKEFHKCCPNAGPVKDLTLPSMLDYVCIQATVEQ-EAGLREVKDMVLLILHVLAEPYNHKFSAFETVNYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALDRHKHHMGSRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQMIIRMRGLPFTATPQDVLGFL-GPECPVTDGTEGLLFVKYPDGRPTGDAFVLFACEEYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY--------------------MSTPLISTLPPPPPPMVSVPVLATPPFITTGNTRDCIRLRGLPYTAAIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKMM-----KDRYVEVFQCSTEEMS-------------------------------FVLMGGTLNRSGLSPPPCKLPCLSPPTYAAFPAAPAMLPTEAALYQPPLLAT--PRTPQAPTHSPAPAFAYYSPQLYMNMNMSYTTYYPSPPVSPSTVSYFAAPPGSVAAAVAAQPTPAILPP----------QPGALVRMQGLPYNAGVKDILSFFQ 680          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:572992])

HSP 1 Score: 365.925 bits (938), Expect = 2.290e-112
Identity = 251/760 (33.03%), Postives = 374/760 (49.21%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLL------PNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIAQFSGFIQTPNQAQTQIQMQNALYQLQILQKQFVSSGIAINQ---VPYPSYWPCIPTSHXXXXXXXXXXXXXXXHILHSPLMGGYFYNIP-VPGQGPRMPAGLQTPSMVNPLNPCNNSYLQSP------LSH-SQPPGLVFSA-SNSPTTFYIPNMGVLQTHNNCQEYAFVVLKNLPKDITLEEIISIFE 2841
            LVVF   TAG     LG+DE  ++L+   I D  ++K  KL +  V      ++E+ K +  L  E+ C            A+PL  VL+  H+S +S  + S+ +  + L  DG   +R   HPE ++ N+ L   + ++ F+DL+KEF +        K L L  M+    I         G+ +   M+ +I  +  + +  K+   ETV   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF + EHRDMAL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT   +L F     CPV  G +G+LFV + DGR TGDAFV+F  EE A+ ALK H++ +G RYIELF+ST AEV QV+N                      M+  LIS L         +P++ +P        R  +R++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+++     K   V+V  CS  +++                               FV  G  +N+    P P   PC+      A             +   PL+       P  P   P       +P +   +N    +Y  SP      +S+ + PPG V +A +  PT   +P           Q  A V ++ LP +  +++I+S F+
Sbjct:    8 LVVFFGATAGANGGKLGSDERELILLVWQIVDLHENKVGKLHRTLVQPDSVDLSEQCKEETGLTAEELC-----------KAEPLESVLQQFHQS-VSAELKSLGRSSYTLCVDGPLLIRQVLHPEASKKNLVLP--ECFYTFVDLKKEFHKCCPNAGPVKDLTLPSMLDYVCIQATVEQ-EAGLREVKDMVLLILHVLAEPYNHKFSAFETVNYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALDRHKHHMGSRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQMIIRMRGLPFTATPQDVLGFL-GPECPVTDGTEGLLFVKYPDGRPTGDAFVLFACEEYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY--------------------MSTPLISTLPPPPPPMVSVPVLATPPFITTGNTRDCIRLRGLPYTAAIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKMM-----KDRYVEVFQCSTEEMS-------------------------------FVLMGGTLNRSGLSPPPCKLPCLSPPTYAAFPAAPAMLPTEAALYQPPLLAT--PRTPQAPTHSPAPAFAYYSPQLYMNMNMSYTTYYPSPPVSPSTVSYFAAPPGSVAAAVAAQPTPAILPP----------QPGALVRMQGLPYNAGVKDILSFFQ 680          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:572992])

HSP 1 Score: 366.311 bits (939), Expect = 2.406e-112
Identity = 252/760 (33.16%), Postives = 374/760 (49.21%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLL------PNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIAQFSGFIQTPNQAQTQIQMQNALYQLQILQKQFVSSGIAINQ---VPYPSYWPCIPTSHXXXXXXXXXXXXXXXHILHSPLMGGYFYNIP-VPGQGPRMPAGLQTPSMVNPLNPCNNSYLQSP------LSH-SQPPGLVFSA-SNSPTTFYIPNMGVLQTHNNCQEYAFVVLKNLPKDITLEEIISIFE 2841
            LVVF   TAG     LG+DE  ++L+   I D  ++K  KL        H ++ + +      L+E C  ET L       A+PL  VL+  H+S +S  + S+ +  + L  DG   +R   HPE ++ N+ L   + ++ F+DL+KEF +        K L L  M+    I         G+ +   M+ +I  +  + +  K+   ETV   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF + EHRDMAL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT   +L F     CPV  G +G+LFV + DGR TGDAFV+F  EE A+ ALK H++ +G RYIELF+ST AEV QV+N                      M+  LIS L         +P++ +P        R  +R++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+++     K   V+V  CS  +++                               FV  G  +N+    P P   PC+      A             +   PL+       P  P   P       +P +   +N    +Y  SP      +S+ + PPG V +A +  PT   +P           Q  A V ++ LP +  +++I+S F+
Sbjct:    8 LVVFFGATAGANGGKLGSDERELILLVWQIVDLHENKVGKL--------HRTLVQPDSVD---LSEQCKEETGLTAEELCKAEPLESVLQQFHQS-VSAELKSLGRSSYTLCVDGPLLIRQVLHPEASKKNLVLP--ECFYTFVDLKKEFHKCCPNAGPVKDLTLPSMLDYVCIQATVEQ-EAGLREVKDMVLLILHVLAEPYNHKFSAFETVNYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALDRHKHHMGSRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQMIIRMRGLPFTATPQDVLGFL-GPECPVTDGTEGLLFVKYPDGRPTGDAFVLFACEEYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY--------------------MSTPLISTLPPPPPPMVSVPVLATPPFITTGNTRDCIRLRGLPYTAAIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKMM-----KDRYVEVFQCSTEEMS-------------------------------FVLMGGTLNRSGLSPPPCKLPCLSPPTYAAFPAAPAMLPTEAALYQPPLLAT--PRTPQAPTHSPAPAFAYYSPQLYMNMNMSYTTYYPSPPVSPSTVSYFAAPPGSVAAAVAAQPTPAILPP----------QPGALVRMQGLPYNAGVKDILSFFQ 680          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:572992])

HSP 1 Score: 366.311 bits (939), Expect = 2.406e-112
Identity = 252/760 (33.16%), Postives = 374/760 (49.21%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLL------PNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIAQFSGFIQTPNQAQTQIQMQNALYQLQILQKQFVSSGIAINQ---VPYPSYWPCIPTSHXXXXXXXXXXXXXXXHILHSPLMGGYFYNIP-VPGQGPRMPAGLQTPSMVNPLNPCNNSYLQSP------LSH-SQPPGLVFSA-SNSPTTFYIPNMGVLQTHNNCQEYAFVVLKNLPKDITLEEIISIFE 2841
            LVVF   TAG     LG+DE  ++L+   I D  ++K  KL        H ++ + +      L+E C  ET L       A+PL  VL+  H+S +S  + S+ +  + L  DG   +R   HPE ++ N+ L   + ++ F+DL+KEF +        K L L  M+    I         G+ +   M+ +I  +  + +  K+   ETV   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF + EHRDMAL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT   +L F     CPV  G +G+LFV + DGR TGDAFV+F  EE A+ ALK H++ +G RYIELF+ST AEV QV+N                      M+  LIS L         +P++ +P        R  +R++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+++     K   V+V  CS  +++                               FV  G  +N+    P P   PC+      A             +   PL+       P  P   P       +P +   +N    +Y  SP      +S+ + PPG V +A +  PT   +P           Q  A V ++ LP +  +++I+S F+
Sbjct:    8 LVVFFGATAGANGGKLGSDERELILLVWQIVDLHENKVGKL--------HRTLVQPDSVD---LSEQCKEETGLTAEELCKAEPLESVLQQFHQS-VSAELKSLGRSSYTLCVDGPLLIRQVLHPEASKKNLVLP--ECFYTFVDLKKEFHKCCPNAGPVKDLTLPSMLDYVCIQATVEQ-EAGLREVKDMVLLILHVLAEPYNHKFSAFETVNYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALDRHKHHMGSRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQMIIRMRGLPFTATPQDVLGFL-GPECPVTDGTEGLLFVKYPDGRPTGDAFVLFACEEYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY--------------------MSTPLISTLPPPPPPMVSVPVLATPPFITTGNTRDCIRLRGLPYTAAIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKMM-----KDRYVEVFQCSTEEMS-------------------------------FVLMGGTLNRSGLSPPPCKLPCLSPPTYAAFPAAPAMLPTEAALYQPPLLAT--PRTPQAPTHSPAPAFAYYSPQLYMNMNMSYTTYYPSPPVSPSTVSYFAAPPGSVAAAVAAQPTPAILPP----------QPGALVRMQGLPYNAGVKDILSFFQ 680          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Match: atf1 (activating transcription factor 1 [Source:Xenbase;Acc:XB-GENE-971677])

HSP 1 Score: 364.77 bits (935), Expect = 4.081e-112
Identity = 215/568 (37.85%), Postives = 309/568 (54.40%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRF---YNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDD--GFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV    TAG     LG+DE  ++ +   + +    K  +L +  V   H  +TEE K   R+            DSL+   Q L   L+  ++S+   ++IG+ +     FC+ TDGQ  +R   HPE ++ NI L   + +++F DLRKEF +     +    L +  M          +   YG  +   M +II  +  +   +K+ + E V   + S    K + + D  ++RARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA ++L FF    CPV  G++GILFV + D R TGDAFV+F  EE A+ ALK H+E +G RYIELF+ST AEV QV+N        P        +            LP   IP +N          R  +R++G+P   T+ DI+ FL ++   I   G H++ N  G+P+G++ IQM S   A L  +  HK+ +     K   V+V  CS  ++
Sbjct:    9 LVVLFTTTAGANGSKLGSDEKEVIQLLWKVINLANKKVGELHEVTVRPDHLELTEECKEITRIEA----------DSLYVAPQ-LEQALQQFNQSVGNELNIGVGT----SFCICTDGQLHIRQVLHPEASKKNILLP--ECFYSFFDLRKEFLKCCPGSSDTNELDVHAMASYLGFEKKSTRYRYGASEVDDMGDIIVTLISEPYNYKFSDPERVNYKFESGTCSKLEIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGNRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVLAFF-GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPV------------LPQPFIPPVNV---------RDCIRLRGLPYAATIEDILEFLGEFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTM-----KDRYVEVFQCSAEEM 529          

HSP 2 Score: 102.834 bits (255), Expect = 1.067e-21
Identity = 77/257 (29.96%), Postives = 120/257 (46.69%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFR---GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVAE-EALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSP 2013
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V     R  G+A + F   E+   AL+KHK  +G+RYIE++ +T  +  QV                   V  Q    P   +  IR+RGLPY AT   ILEF        EF  D    G+  V +  GR +GD+F+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+                      T+N N +S  P ++P ++ P
Sbjct:  325 NQVIVRMRGLPFTATAEEVLAFFGQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPVLPQPFIPPVNVRDCIRLRGLPYAATIEDILEFLG------EFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTMKDRYVEVFQCSAEEMNFVLMGG-------------------TLNRNGLSPPPCKLPCLSPP 556          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Match: atf1 (activating transcription factor 1 [Source:Xenbase;Acc:XB-GENE-971677])

HSP 1 Score: 358.221 bits (918), Expect = 6.910e-110
Identity = 214/563 (38.01%), Postives = 306/563 (54.35%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV    TAG     LG+DE  ++ +   + +    K  +L +  V   H  +TEE K   R+            DSL+   Q L   L+  ++S+   ++IG+ +     FC+ TDGQ  +R   HPE ++ NI L   + +++F DLRKEF +                C    +D+      +  H M   I  ++D  +K+ + E V   + S    K + + D  ++RARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA ++L FF    CPV  G++GILFV + D R TGDAFV+F  EE A+ ALK H+E +G RYIELF+ST AEV QV+N        P        +            LP   IP +N          R  +R++G+P   T+ DI+ FL ++   I   G H++ N  G+P+G++ IQM S   A L  +  HK+ +     K   V+V  CS  ++
Sbjct:    9 LVVLFTTTAGANGSKLGSDEKEVIQLLWKVINLANKKVGELHEVTVRPDHLELTEECKEITRIEA----------DSLYVAPQ-LEQALQQFNQSVGNELNIGVGT----SFCICTDGQLHIRQVLHPEASKKNILLP--ECFYSFFDLRKEFLK----------------CCPGSSDTNE----LDVHAMASCIL-LSD--YKFSDPERVNYKFESGTCSKLEIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGNRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVLAFF-GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPV------------LPQPFIPPVNV---------RDCIRLRGLPYAATIEDILEFLGEFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTM-----KDRYVEVFQCSAEEM 501          

HSP 2 Score: 101.293 bits (251), Expect = 3.300e-21
Identity = 70/215 (32.56%), Postives = 108/215 (50.23%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAE----------VFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVAE-EALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V     R  G+A + F   E+   AL+KHK  +G+RYIE++ +T  +  QV    +              V  Q    P   +  IR+RGLPY AT   ILEF        EF  D    G+  V +  GR +GD+F+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+
Sbjct:  297 NQVIVRMRGLPFTATAEEVLAFFGQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPVLPQPFIPPVNVRDCIRLRGLPYAATIEDILEFLG------EFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTMKDRYVEVFQCSAEEMNFVL 505          

HSP 3 Score: 54.299 bits (129), Expect = 1.117e-6
Identity = 32/90 (35.56%), Postives = 50/90 (55.56%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFRGL--NIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            +R RGLP+ AT  DI +F      +I   G+ +VL+  GR +G++ I+ KS +   +A +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  420 IRLRGLPYAATIEDILEFLGEFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTMKDRYVEVFQCSAEEMNFVLMGGT 509          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Match: atf1 (activating transcription factor 1 [Source:Xenbase;Acc:XB-GENE-971677])

HSP 1 Score: 353.984 bits (907), Expect = 2.971e-109
Identity = 213/563 (37.83%), Postives = 302/563 (53.64%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV    TAG     LG+DE  ++ +   + +    K  +L +  V   H  +TEE K   R+            DSL+   Q L   L+  ++S+   ++IG+ +     FC+ TDGQ  +R   HPE ++ NI L   + +++F DLRKEF +                C    +D+      +  H M   I  +    F   + E V   + S    K + + D  ++RARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA ++L FF    CPV  G++GILFV + D R TGDAFV+F  EE A+ ALK H+E +G RYIELF+ST AEV QV+N        P        +            LP   IP +N          R  +R++G+P   T+ DI+ FL ++   I   G H++ N  G+P+G++ IQM S   A L  +  HK+ +     K   V+V  CS  ++
Sbjct:    9 LVVLFTTTAGANGSKLGSDEKEVIQLLWKVINLANKKVGELHEVTVRPDHLELTEECKEITRIEA----------DSLYVAPQ-LEQALQQFNQSVGNELNIGVGT----SFCICTDGQLHIRQVLHPEASKKNILLP--ECFYSFFDLRKEFLK----------------CCPGSSDTNE----LDVHAMASCI--LLSGAFS--DPERVNYKFESGTCSKLEIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGNRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVLAFF-GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPV------------LPQPFIPPVNV---------RDCIRLRGLPYAATIEDILEFLGEFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTM-----KDRYVEVFQCSAEEM 500          

HSP 2 Score: 100.908 bits (250), Expect = 3.257e-21
Identity = 70/215 (32.56%), Postives = 107/215 (49.77%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVAE-EALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V     R  G+A + F   E+   AL+KHK  +G+RYIE++ +T  +  QV                   V  Q    P   +  IR+RGLPY AT   ILEF        EF  D    G+  V +  GR +GD+F+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+
Sbjct:  296 NQVIVRMRGLPFTATAEEVLAFFGQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPVLPQPFIPPVNVRDCIRLRGLPYAATIEDILEFLG------EFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTMKDRYVEVFQCSAEEMNFVL 504          

HSP 3 Score: 54.299 bits (129), Expect = 1.169e-6
Identity = 32/91 (35.16%), Postives = 50/91 (54.95%), Query Frame = 1
Query: 1312 VVRARGLPWQATDSDINKFFR--GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
             +R RGLP+ AT  DI +F      +I   G+ +VL+  GR +G++ I+ KS +   +A +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  418 CIRLRGLPYAATIEDILEFLGEFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTMKDRYVEVFQCSAEEMNFVLMGGT 508          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Match: atf1 (activating transcription factor 1 [Source:Xenbase;Acc:XB-GENE-971677])

HSP 1 Score: 352.058 bits (902), Expect = 1.754e-107
Identity = 212/564 (37.59%), Postives = 304/564 (53.90%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFY-NKEKSLVLDEMIQECNIFINDSGGN---YGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSG 2298
            LVV    TAG     LG+DE  ++ +   + +    K  +L +  V   H  +TEE K   R+            DSL+   Q L   L+  ++S+   ++IG+ +     FC+ TDGQ  +R   HPE ++ NI L   + +++F DLRKEF +       +  LD       I ++ +      YG  +   M +II  +  + +            + +   K + + D  ++RARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA ++L FF    CPV  G++GILFV + D R TGDAFV+F  EE A+ ALK H+E +G RYIELF+ST AEV QV+N        P        +            LP   IP +N          R  +R++G+P   T+ DI+ FL ++   I   G H++ N  G+P+G++ IQM S   A L  +  HK+ +     K   V+V  CS 
Sbjct:    9 LVVLFTTTAGANGSKLGSDEKEVIQLLWKVINLANKKVGELHEVTVRPDHLELTEECKEITRIEA----------DSLYVAPQ-LEQALQQFNQSVGNELNIGVGT----SFCICTDGQLHIRQVLHPEASKKNILLP--ECFYSFFDLRKEFLKCCPGSSDTNELDVHAMASCILLSGAKSTRYRYGASEVDDMGDIIVTLISEPYNIFSLLISDVFLFHS--SKLEIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGNRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVLAFF-GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPV------------LPQPFIPPVNV---------RDCIRLRGLPYAATIEDILEFLGEFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTM-----KDRYVEVFQCSA 523          

HSP 2 Score: 102.834 bits (255), Expect = 1.091e-21
Identity = 77/257 (29.96%), Postives = 121/257 (47.08%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAE----------VFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVAE-EALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSP 2013
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V     R  G+A + F   E+   AL+KHK  +G+RYIE++ +T  +  QV    +              V  Q    P   +  IR+RGLPY AT   ILEF        EF  D    G+  V +  GR +GD+F+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+                      T+N N +S  P ++P ++ P
Sbjct:  322 NQVIVRMRGLPFTATAEEVLAFFGQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPVLPQPFIPPVNVRDCIRLRGLPYAATIEDILEFLG------EFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTMKDRYVEVFQCSAEEMNFVLMGG-------------------TLNRNGLSPPPCKLPCLSPP 553          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Match: atf1 (activating transcription factor 1 [Source:Xenbase;Acc:XB-GENE-971677])

HSP 1 Score: 347.436 bits (890), Expect = 3.520e-106
Identity = 212/563 (37.66%), Postives = 301/563 (53.46%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV    TAG     LG+DE  ++ +   + +    K  +L +  V   H  +TEE K   R+            DSL+   Q L   L+  ++S+   ++IG+ +     FC+ TDGQ  +R   HPE ++ NI L   + +++F DLRKEF +                C    +D+      +  H M   I  ++   F    T+    H       K + + D  ++RARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA ++L FF    CPV  G++GILFV + D R TGDAFV+F  EE A+ ALK H+E +G RYIELF+ST AEV QV+N        P        +            LP   IP +N          R  +R++G+P   T+ DI+ FL ++   I   G H++ N  G+P+G++ IQM S   A L  +  HK+ +     K   V+V  CS  ++
Sbjct:    9 LVVLFTTTAGANGSKLGSDEKEVIQLLWKVINLANKKVGELHEVTVRPDHLELTEECKEITRIEA----------DSLYVAPQ-LEQALQQFNQSVGNELNIGVGT----SFCICTDGQLHIRQVLHPEASKKNILLP--ECFYSFFDLRKEFLK----------------CCPGSSDTNE----LDVHAMASCIL-LSGAAF----TDVFLFH-----SSKLEIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGNRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVLAFF-GQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPV------------LPQPFIPPVNV---------RDCIRLRGLPYAATIEDILEFLGEFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTM-----KDRYVEVFQCSAEEM 494          

HSP 2 Score: 102.834 bits (255), Expect = 9.833e-22
Identity = 77/257 (29.96%), Postives = 120/257 (46.69%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVAE-EALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSP 2013
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V     R  G+A + F   E+   AL+KHK  +G+RYIE++ +T  +  QV                   V  Q    P   +  IR+RGLPY AT   ILEF        EF  D    G+  V +  GR +GD+F+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+                      T+N N +S  P ++P ++ P
Sbjct:  290 NQVIVRMRGLPFTATAEEVLAFFGQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPVLPQPFIPPVNVRDCIRLRGLPYAATIEDILEFLG------EFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTMKDRYVEVFQCSAEEMNFVLMGG-------------------TLNRNGLSPPPCKLPCLSPP 521          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Match: Esrp1 (epithelial splicing regulatory protein 1 [Source:MGI Symbol;Acc:MGI:1917326])

HSP 1 Score: 381.719 bits (979), Expect = 1.286e-119
Identity = 220/565 (38.94%), Postives = 317/565 (56.11%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSG 2298
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   +DS   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H+E +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS 
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHIRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTM-----KDRYVEVFQCSA 525          

HSP 2 Score: 106.686 bits (265), Expect = 3.261e-23
Identity = 72/215 (33.49%), Postives = 110/215 (51.16%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVL 532          

HSP 3 Score: 55.8398 bits (133), Expect = 2.541e-7
Identity = 34/90 (37.78%), Postives = 49/90 (54.44%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFR--GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            +R RGLP+ AT  DI  F      +I   G+ +VL+  GR +G+A I+ KS +   MA +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  447 IRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGGT 536          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Match: Esrp1 (epithelial splicing regulatory protein 1 [Source:MGI Symbol;Acc:MGI:1917326])

HSP 1 Score: 383.259 bits (983), Expect = 3.092e-119
Identity = 220/568 (38.73%), Postives = 319/568 (56.16%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   +DS   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H+E +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS  ++
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHIRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTM-----KDRYVEVFQCSAEEM 528          

HSP 2 Score: 109.383 bits (272), Expect = 7.306e-24
Identity = 79/257 (30.74%), Postives = 123/257 (47.86%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFR---GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSP 2013
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+                      T+N N +S  P ++P ++ P
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGG-------------------TLNRNGLSPPPCKLPCLSPP 555          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Match: Esrp1 (epithelial splicing regulatory protein 1 [Source:MGI Symbol;Acc:MGI:1917326])

HSP 1 Score: 382.104 bits (980), Expect = 4.852e-119
Identity = 220/568 (38.73%), Postives = 319/568 (56.16%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   +DS   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H+E +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS  ++
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHIRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTM-----KDRYVEVFQCSAEEM 528          

HSP 2 Score: 107.457 bits (267), Expect = 2.575e-23
Identity = 72/215 (33.49%), Postives = 110/215 (51.16%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVL 532          

HSP 3 Score: 56.225 bits (134), Expect = 2.424e-7
Identity = 34/90 (37.78%), Postives = 49/90 (54.44%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFR--GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            +R RGLP+ AT  DI  F      +I   G+ +VL+  GR +G+A I+ KS +   MA +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  447 IRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGGT 536          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Match: Esrp1 (epithelial splicing regulatory protein 1 [Source:MGI Symbol;Acc:MGI:1917326])

HSP 1 Score: 382.489 bits (981), Expect = 4.964e-119
Identity = 220/568 (38.73%), Postives = 319/568 (56.16%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   +DS   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H+E +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS  ++
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHIRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTM-----KDRYVEVFQCSAEEM 528          

HSP 2 Score: 107.457 bits (267), Expect = 2.614e-23
Identity = 72/215 (33.49%), Postives = 110/215 (51.16%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVL 532          

HSP 3 Score: 56.225 bits (134), Expect = 2.275e-7
Identity = 34/90 (37.78%), Postives = 49/90 (54.44%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFR--GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            +R RGLP+ AT  DI  F      +I   G+ +VL+  GR +G+A I+ KS +   MA +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  447 IRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGGT 536          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Match: Esrp2 (epithelial splicing regulatory protein 2 [Source:MGI Symbol;Acc:MGI:1924661])

HSP 1 Score: 369.392 bits (947), Expect = 1.418e-113
Identity = 207/560 (36.96%), Postives = 307/560 (54.82%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNK---EKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTD--DGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACS 2295
            LVV    TAG    DLG+DET ++L+   ++  ++ +S      QV   H+S+   E      L+  C   + L+      A+ L  VL+   + L+S  +  +    + L TDGQ  +R   HPE +R N+ L   D +F+F DLR+EF   +      + L +  M Q+  +  + +  ++G+ +   M+ +I  + +  +G  + + E V + Y +    K+D V +E VVRARGLPWQ++D D+ +FF+GLNI +GG+AL L+  GRRNGEALIRF   E RD+AL++HKHHMG RYIEVY ATG +F+++AGG + E   FL R     Q ++R+RGLP++A    +L F     CPV  G DG+LFV H DGR TGDAF +F  EE+A+ AL+ H+  +G RYIELF+ST AEV QV+N        P        I      G                       GR  VR++G+P   T+ DI++FL +    I   G H++ N  G+P+G+A IQM+S + A    +  HK+++     K+  V+V  CS
Sbjct:   30 LVVLFGATAGALGPDLGSDETDLILL---VWQVVEPRS-----RQVGTLHKSLVRAEAAA---LSPQCREASGLSADSLARAESLDKVLQQFSQ-LVSGDVALLGGGPYVLCTDGQQLLRQVLHPEASRKNLVLP--DTFFSFYDLRREFHMQHPSTCSARDLTVGTMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGSNGQLFSKPEVVKQKYETGPCSKADVVDNETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSR---EDQVILRLRGLPFSAGPTDVLGFL-GPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYAASPLLPTLTAPLLPIPFPLAGGT----------------------GRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMMSVERALAAAQRCHKKMM-----KERYVEVVPCS 544          

HSP 2 Score: 51.9878 bits (123), Expect = 4.701e-6
Identity = 33/90 (36.67%), Postives = 48/90 (53.33%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHR-DMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            VR RGLP+ AT  DI  F      +I   G+ +VL++ GR +G+A I+  S E     A R HK  M +RY+EV   +  +  +V  G +
Sbjct:  467 VRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMMSVERALAAAQRCHKKMMKERYVEVVPCSTEEMSRVLMGGS 556          
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Match: sp|A1L1G1|ESRP1_DANRE (Epithelial splicing regulatory protein 1 OS=Danio rerio OX=7955 GN=esrp1 PE=2 SV=1)

HSP 1 Score: 389.808 bits (1000), Expect = 1.781e-120
Identity = 225/569 (39.54%), Postives = 318/569 (55.89%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDG--FKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQI-----PMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LV+    T+G   D LG+DE  IV +   + D    K+ ++ +  V   H  ++EE           C   + L D   T   PL   +  L++ L +  + + +   F L TDGQ  +R   HPE +  NI L   D +F+F DLRKEF++ +  E   K L L  M    N+ ++ S   +   +  +M++I+  +  +    ++   E V + + +    K + V D  V+RARGLPWQ++D DI +FFRGLNI KGG AL L+  GRRNGEAL+RF+S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL R    +Q ++RMRGLP+ ATA Q+L+FF S  CPV  G +GILFV   DGR TGDAFV+F  EE A+ ALK H++ +G RYIELFKST AEV QV+N                       +  LI + P+ I     P    P    +   R  VR++G+P + ++ DI+ FL +YG  I   G H++ N  G+P+GEA IQM S + A L  +  HK+     S K+  V+V ACS  ++
Sbjct:    8 LVLLFTTTSGASGDKLGSDEKEIVQLVWQVVDLATKKAGQVNELLVKPDHIELSEE-----------CQELSGLTDEALTPVDPLEVAIDQLNQRLCA-EVDTGAGNTFYLCTDGQLHVRQVLHPEASSKNILLP--DCFFSFFDLRKEFKKEFPSEVKLKDLNLQVMADHLNVAVDSSLHAFTAYKVQQMVDIVLALISEPTCHEFTFPEKVNEKFETGTCSKMERVDDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFESEEHRDLALQRHKHHMGGRYIEVYKATGEDFLKIAGGTSNEVASFLSR---ENQIIVRMRGLPFNATAEQVLQFF-SPACPVTDGSEGILFVRFPDGRPTGDAFVLFSCEEHAQNALKKHKDMLGKRYIELFKSTAAEVQQVLNKYS--------------------SAPLIPVAPSPILSVVAPPTFVPQTAAVPGVRDCVRLRGLPYDASIQDILVFLGEYGADIKTHGVHMVLNHQGRPSGEAFIQMRSAERAFLAAQRCHKR-----SMKERYVEVFACSAQEV 533          

HSP 2 Score: 100.908 bits (250), Expect = 2.403e-20
Identity = 68/220 (30.91%), Postives = 108/220 (49.09%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFR-GLNIEKG--GIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEV------FLQRITKPS-----------QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++++VR RGLP+ AT   + +FF     +  G  GI  V    GR  G+A + F   EH   AL+KHK  +G+RYIE++ +T  +  QV    +    +       L  +  P+           +  +R+RGLPY A+   IL F        E+G D    G+  V +  GR +G+AF+   + E A   A + H+ ++  RY+E+F  +  EVN V+
Sbjct:  324 NQIIVRMRGLPFNATAEQVLQFFSPACPVTDGSEGILFVRFPDGRPTGDAFVLFSCEEHAQNALKKHKDMLGKRYIELFKSTAAEVQQVLNKYSSAPLIPVAPSPILSVVAPPTFVPQTAAVPGVRDCVRLRGLPYDASIQDILVFLG------EYGADIKTHGVHMVLNHQGRPSGEAFIQMRSAERAFLAAQRCHKRSMKERYVEVFACSAQEVNIVL 537          

HSP 3 Score: 59.3066 bits (142), Expect = 1.745e-7
Identity = 35/90 (38.89%), Postives = 52/90 (57.78%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMAL-RKHKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            VR RGLP+ A+  DI  F    G +I+  G+ +VL+  GR +GEA I+ +S E   +A  R HK  M +RY+EV+  + ++   V  G T
Sbjct:  452 VRLRGLPYDASIQDILVFLGEYGADIKTHGVHMVLNHQGRPSGEAFIQMRSAERAFLAAQRCHKRSMKERYVEVFACSAQEVNIVLMGGT 541          
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Match: sp|B2RYD2|ESRP1_RAT (Epithelial splicing regulatory protein 1 OS=Rattus norvegicus OX=10116 GN=Esrp1 PE=2 SV=2)

HSP 1 Score: 384.8 bits (987), Expect = 5.955e-119
Identity = 223/568 (39.26%), Postives = 322/568 (56.69%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSL-VLD--EMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++       L  LD   M +  N   NDS   YG  Q   M  II  M  + +  ++ + E V   + S    K++ +    VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H++ +G RYIELF+ST AEV QV+N        P                 +I +LP Q +P  N          R  VR++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS  ++
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHVRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDLDKLDVAAMAESLNFEKNDSMSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKTELIDGNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLP------------TAPIIPVLPQQFVPPTNV---------RDCVRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTM-----KDRYVEVFQCSAEEM 528          

HSP 2 Score: 106.686 bits (265), Expect = 3.480e-22
Identity = 71/215 (33.02%), Postives = 111/215 (51.63%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFR---GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEA----------EVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV    +              V  Q+   P+  +  +R+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTAPIIPVLPQQFVPPTNVRDCVRLRGLPYAATIEDILDFLG------EFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVL 532          

HSP 3 Score: 56.9954 bits (136), Expect = 9.452e-7
Identity = 35/90 (38.89%), Postives = 49/90 (54.44%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFR--GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            VR RGLP+ AT  DI  F      +I   G+ +VL+  GR +G+A I+ KS +   MA +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  447 VRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGGT 536          
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Match: sp|Q3US41|ESRP1_MOUSE (Epithelial splicing regulatory protein 1 OS=Mus musculus OX=10090 GN=Esrp1 PE=1 SV=2)

HSP 1 Score: 379.022 bits (972), Expect = 8.785e-117
Identity = 220/568 (38.73%), Postives = 319/568 (56.16%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   +DS   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H+E +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS  ++
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLLWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDAENLSSAPQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHIRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVAAMTESLNFEKSDSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTC-KMELIDDSTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTM-----KDRYVEVFQCSAEEM 527          

HSP 2 Score: 109.383 bits (272), Expect = 5.462e-23
Identity = 79/257 (30.74%), Postives = 123/257 (47.86%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFR---GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSP 2013
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++ + +RY+E+F+ +  E+N V+                      T+N N +S  P ++P ++ P
Sbjct:  323 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKELLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFSTDIRTHGVHMVLNHQGRPSGDAFIQMKSTDRAFMAAQKYHKKTMKDRYVEVFQCSAEEMNFVLMGG-------------------TLNRNGLSPPPCKLPCLSPP 554          
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Match: sp|Q6NXG1|ESRP1_HUMAN (Epithelial splicing regulatory protein 1 OS=Homo sapiens OX=9606 GN=ESRP1 PE=1 SV=2)

HSP 1 Score: 377.481 bits (968), Expect = 3.023e-116
Identity = 218/568 (38.38%), Postives = 318/568 (55.99%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL---ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ-IPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LVV   +TAG     LG+DE  ++L+   + D    K  +L        HE +   ++ +   LTEDC  ET ++    + A  L   L+  ++S+   ++IG+ +     FCL TDGQ  +R   HPE ++ N+ L   + +++F DLRKEF++          L +  M +  N   + S   YG  Q   M  II  M  + +  ++ + E V   + S    K + + D  VVRARGLPWQ++D DI +FF+GLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL   +K +Q ++RMRGLP+TATA +++ FF   +CP+  G++GILFV + DGR TGDAFV+F  EE A+ AL+ H++ +G RYIELF+ST AEV QV+N        P        +            LP Q +P  N          R  +R++G+P   T+ DI++FL ++   I   G H++ N  G+P+G+A IQM S   A +  +  HK+ +     K   V+V  CS  ++
Sbjct:    8 LVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQL--------HEVLVRPDQLE---LTEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGT----SFCLCTDGQLHVRQILHPEASKKNVLLP--ECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFL---SKENQVIVRMRGLPFTATAEEVVAFF-GQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPV------------LPQQFVPPTNV---------RDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNM-----KDRYVEVFQCSAEEM 528          

HSP 2 Score: 112.464 bits (280), Expect = 5.844e-24
Identity = 80/257 (31.13%), Postives = 124/257 (48.25%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFR---GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV----------AGGDTEEAEVFLQRITKPS--QTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSP 2013
            ++V+VR RGLP+ AT  ++  FF     +   K GI  V    GR  G+A + F   E+   ALRKHK  +G+RYIE++ +T  +  QV                   V  Q+   P+  +  IR+RGLPY AT   IL+F        EF  D    G+  V +  GR +GDAF+  ++ + A   A K H++N+ +RY+E+F+ +  E+N V+                      T+N N +S  P ++P ++ P
Sbjct:  324 NQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLG------EFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGG-------------------TLNRNGLSPPPCKLPCLSPP 555          
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Match: sp|Q8K0G8|ESRP2_MOUSE (Epithelial splicing regulatory protein 2 OS=Mus musculus OX=10090 GN=Esrp2 PE=1 SV=1)

HSP 1 Score: 369.392 bits (947), Expect = 9.916e-113
Identity = 207/560 (36.96%), Postives = 307/560 (54.82%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNK---EKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTD--DGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACS 2295
            LVV    TAG    DLG+DET ++L+   ++  ++ +S      QV   H+S+   E      L+  C   + L+      A+ L  VL+   + L+S  +  +    + L TDGQ  +R   HPE +R N+ L   D +F+F DLR+EF   +      + L +  M Q+  +  + +  ++G+ +   M+ +I  + +  +G  + + E V + Y +    K+D V +E VVRARGLPWQ++D D+ +FF+GLNI +GG+AL L+  GRRNGEALIRF   E RD+AL++HKHHMG RYIEVY ATG +F+++AGG + E   FL R     Q ++R+RGLP++A    +L F     CPV  G DG+LFV H DGR TGDAF +F  EE+A+ AL+ H+  +G RYIELF+ST AEV QV+N        P        I      G                       GR  VR++G+P   T+ DI++FL +    I   G H++ N  G+P+G+A IQM+S + A    +  HK+++     K+  V+V  CS
Sbjct:   30 LVVLFGATAGALGPDLGSDETDLILL---VWQVVEPRS-----RQVGTLHKSLVRAEAAA---LSPQCREASGLSADSLARAESLDKVLQQFSQ-LVSGDVALLGGGPYVLCTDGQQLLRQVLHPEASRKNLVLP--DTFFSFYDLRREFHMQHPSTCSARDLTVGTMAQDLGLETDATEDDFGVWEVKTMVAVILHLLEGSNGQLFSKPEVVKQKYETGPCSKADVVDNETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSR---EDQVILRLRGLPFSAGPTDVLGFL-GPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYAASPLLPTLTAPLLPIPFPLAGGT----------------------GRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMMSVERALAAAQRCHKKMM-----KERYVEVVPCS 544          
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Match: A0A267EB47 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017860g1 PE=4 SV=1)

HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0
Identity = 289/567 (50.97%), Postives = 383/567 (67.55%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQY----QVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGI-PSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLV--LDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNG-NLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LV  H+ T GKQ +++GTDE  I LI   I+D   +K I +EQ+    QV+         E++    ++E+C  ET L+   F  A  L  VL+++ K L + GI P      F LV +GQ PMRL FHPE     I L  + Y+++F DLRKEF +  N E   +  L +M+    +  ++S  +YG  QC  M  +I ++ +DG  +KE E V + YY AIVRK+D V DE VVRARGLPWQATD+DI+KFFRGLNI  GGIALVLSKVGRRNGEALIRF S+EHRD+AL+KH+HHM QRYIEVY ATGRDF+ VAG DT+E E FL ++T+P+Q+L+RMRGLPYT +A++IL+FF    CPV+F  +G+LFVNHKDGRATGDAFVIFENE +AE AL++HR++IGNRYIELFKSTPAEVNQV+ S   P  +               NG +  +  P  +P      L   N  + F+R++GMP++ +VADI+NFLE + Q I +QG H++YN +GQPAGEAIIQM SE AA +  EAK+++L  + +GK+S V+VS C+  ++
Sbjct:   83 LVALHLTTCGKQGEEIGTDEAPICLIAYLIHDVRHNKIIAVEQHLVKPQVNPGQTGSDSSEEDGLATISEECRSETGLSADSFHSASYLESVLEEMDKFLRNKGIHPESGGKTFTLVLEGQHPMRLVFHPETCSKKISLEQFPYFYSFFDLRKEFLKGRNSEPDTIVSLKDMLDSLEMQFDNSP-DYGTRQCIAMSRVISRLLNDGHTFKEPEKVNQFYYPAIVRKTDTVDDESVVRARGLPWQATDADIHKFFRGLNISAGGIALVLSKVGRRNGEALIRFDSQEHRDIALKKHRHHMQQRYIEVYRATGRDFVAVAGADTKEGENFLAKLTEPTQSLVRMRGLPYTVSADEILDFFRKAECPVQFDSEGVLFVNHKDGRATGDAFVIFENEILAERALQNHRQHIGNRYIELFKSTPAEVNQVLCSFKNPQQAE--------------NGHDNPANAPGLLPFTPLSLLQPPNFSKMFIRVRGMPVDASVADILNFLEGHSQNIVFQGVHLVYNHIGQPAGEAIIQMSSELAAHMACEAKNRKLFYLPTGKRSQVEVSQCAPHEV 634          
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Match: A0A267FI41 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig034309g1 PE=4 SV=1)

HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0
Identity = 289/567 (50.97%), Postives = 383/567 (67.55%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQY----QVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGI-PSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLV--LDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNG-NLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LV  H+ T GKQ +++GTDE  I LI   I+D   +K I +EQ+    QV+         E++    ++E+C  ET L+   F  A  L  VL+++ K L + GI P      F LV +GQ PMRL FHPE     I L  + Y+++F DLRKEF +  N E   +  L +M+    +  ++S  +YG  QC  M  +I ++ +DG  +KE E V + YY AIVRK+D V DE VVRARGLPWQATD+DI+KFFRGLNI  GGIALVLSKVGRRNGEALIRF S+EHRD+AL+KH+HHM QRYIEVY ATGRDF+ VAG DT+E E FL ++T+P+Q+L+RMRGLPYT +A++IL+FF    CPV+F  +G+LFVNHKDGRATGDAFVIFENE +AE AL++HR++IGNRYIELFKSTPAEVNQV+ S   P  +               NG +  +  P  +P      L   N  + F+R++GMP++ +VADI+NFLE + Q I +QG H++YN +GQPAGEAIIQM SE AA +  EAK+++L  + +GK+S V+VS C+  ++
Sbjct:   83 LVALHLTTCGKQGEEIGTDEAPICLIAYLIHDVRHNKIIAVEQHLVKPQVNPGQTGSDNSEEDGLATISEECRSETGLSADSFHSASYLESVLEEMDKFLRNKGIHPESGGKTFTLVLEGQHPMRLVFHPETCSKKISLEQFPYFYSFFDLRKEFLKGRNSEPDTIVSLKDMLDSLEMQFDNSP-DYGTRQCIAMSRVISRLLNDGHTFKEPEKVNQFYYPAIVRKTDTVDDESVVRARGLPWQATDADIHKFFRGLNISAGGIALVLSKVGRRNGEALIRFDSQEHRDIALKKHRHHMQQRYIEVYRATGRDFVAVAGADTKEGENFLAKLTEPTQSLVRMRGLPYTVSADEILDFFRKAECPVQFDSEGVLFVNHKDGRATGDAFVIFENEILAERALQNHRQHIGNRYIELFKSTPAEVNQVLCSFKNPQQAE--------------NGHDNPANAPGLLPFTPLSLLQPPNFSKMFIRVRGMPVDASVADILNFLEGHSQNIVFQGVHLVYNHIGQPAGEAIIQMSSELAAHMACEAKNRKLFYLPTGKRSQVEVSQCAPHEV 634          
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Match: A0A210PZV8 (Epithelial splicing regulatory protein 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT13722 PE=4 SV=1)

HSP 1 Score: 475.707 bits (1223), Expect = 2.252e-150
Identity = 301/804 (37.44%), Postives = 438/804 (54.48%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGI-PSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFT--STNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMN-SVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI-----AQFSGFIQTPNQAQTQIQMQNALYQLQILQKQFVSSGIAINQVPYPSYWPCIPTSHXXXXXXXXXXXXXXXHILHSPLMGGYFYNIPVPGQGPRMPAGLQTPSMVNPLNPCNNSYLQSPLSHSQPPGLVFSASNSPTTFYIPNMGVLQTHNNCQEYAFVVLKNLPKDITLEEIISIFEPVIQQGINITDIKVGITSDNSATGEAFVAFLNRLDAEKSVIECQSRYVRNAPVDISLL 3015
            L++    TAGK  +DLG DE  IV+    ++D    K + ++   V  +   ++E       +LTEDC LET L++     +QPL  VL +  + L + G+ P      FCL+TDGQ+ +R   HPE +  N+ + +Y  +  F DLRK+F++FY  +    +  MI    +   D    YG+ Q  +M  I++++ +DG  + E + + +     I  KSD V D  VVRARGLPWQ++D DI +FF+GLNI KGG+AL LS  GRRNGEAL+RF+  EHRD+AL++HKHH+GQRYIEVY A+G+DF+ VAGG   EA+ FL R     Q +IRMRGLP+T+T+ Q+LEFF      C V  GEDGILFV++ DGR+TGDAFV+  +E+ A  ALK HRE +G RYIELFKST AEV QV+N S+    P P     P LIA +     L  +  N   MI S         R  VR++ +P    V DI+NFL ++ Q+I YQG H++Y + G+P+GEA IQM SE+AA L    ++K+ + I   KK ++DV  CSG D+     +   GF     QA    Q        Q+LQ+Q +S  I     P P+    IPTS                  L +P +   + ++P P Q    PA + T      + P    Y          P +++   + P +   P   V QT   C     VVL+ +P + +++++++ F    +  +    I++    D    GEA V F+ R +AE+++I+     + N  +D+ L+
Sbjct:    6 LLICFCATAGKNGEDLGVDEQQIVVFVSLLFDVTNCKVVAVQHQYVRPQPTELSET------ILTEDCKLETGLDEDAIKNSQPLEHVLDEFERFLSAKGVHPENGGKSFCLLTDGQSHLRQCLHPEASNKNVTIPSY--FNKFFDLRKQFRKFYKTDNIHNIKSMIDYLGL-QEDHSVEYGVRQVQEMAGIVQRLINDGHTFVEPDVINERLEPGICSKSDIVDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGVALCLSPQGRRNGEALVRFQDGEHRDLALKRHKHHIGQRYIEVYKASGKDFVDVAGGSNTEAQAFLSR---GGQVIIRMRGLPFTSTSQQVLEFFAREPNPCTVLDGEDGILFVHYPDGRSTGDAFVLLASEDEASNALKKHREIMGTRYIELFKSTTAEVQQVLNRSMDPRNPEPLETQLPPLIAQIPQQTALPYIPQN---MITS------GTKRDCVRLRNLPSVAQVTDILNFLGEFSQFIVYQGVHMVYTAQGEPSGEAFIQMDSEEAAQLTTLNRYKKAM-IFGQKKRIIDVIQCSGEDMNLVLTSGIGGFPPAMQQATLAPQPHT-----QLLQRQLISQAIH----PAPTM---IPTS-----------------ALTTPSLS--YAHLPQPFQTAFPPATMPT------MQPRPAYY----------PPIIYWYPSPPIS---PQTIVSQT-GPCP----VVLRGIPFNTSMQDLMNFFGGFPE--VTPESIQLQALPDGRPNGEAVVTFVTRGEAERAIIQLNKNTIGNCVIDLFLV 730          
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Match: A0A2T7NHQ0 (RRM domain-containing protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_18852 PE=4 SV=1)

HSP 1 Score: 476.093 bits (1224), Expect = 2.296e-150
Identity = 256/568 (45.07%), Postives = 354/568 (62.32%), Query Frame = 1
Query:  622 TGILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGI-PSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTL--IRMRGLPYTATANQILEFFTS--TNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIA 2310
            T  LV+  +V+AGK  +DLG+DE  IV +   IYD    K + L+ + V  +   + E       +LT++C  ET L+++     QPL FVL++L KSLIS G+ P      FC +TDGQ  MR   H E    N+ L +Y  ++ F DLRKEF++ Y+      +  M+    +   D    YG+ +   M+ I R++ +DG  + E+E V +   S I  K +YV D  VVRARGLPWQ++D DI +FFRGLNI KGG+AL LS  GRRNGEALIRF+S EHRD+ALR+HKHH+GQRYIEVY A+G+DFI VAGG   EA+ FL R     QTL  +RMRGLP+TAT  Q+LEFF+    +C V  GE+GILFV++ DGR+TGDAFV+F +EE + +ALK HRE++G RYIELFKST AEV QV+N  + P       +             LI+ LP  IP++    L      R  +R++ +P    V DI+ FL ++ QYI YQG H++  + G+P+GE+ IQ+ SE+AA L    KH++ ++ ++ KK ++DV  CSG D++
Sbjct:    8 TSHLVMLFVVSAGKNGEDLGSDEEQIVFLVYLIYDVTNDKVVTLKAHYVKPQPTDLAET------ILTDECKEETGLDENAVRNGQPLDFVLEELDKSLISKGVHPDQGGGSFCFLTDGQCHMRQCVHHEACSKNMSLPSY--FYRFYDLRKEFRKRYDYGPVTSVKAMLDYLGL-DEDQSAEYGVRRSQDMVSIARRLINDGHVFGESEVVNERLESGICTKDEYVDDNTVVRARGLPWQSSDQDIARFFRGLNIAKGGVALCLSPQGRRNGEALIRFESDEHRDLALRRHKHHIGQRYIEVYKASGKDFINVAGGSNTEAQAFLSR---GGQTLMIVRMRGLPFTATTAQVLEFFSREPNSCQVLDGEEGILFVHYPDGRSTGDAFVLFSSEEESSKALKKHRESMGQRYIELFKSTTAEVQQVLNRNMDPRNPEQPENQLPP---------LIAQLPTAIPLVPQ-NLITTGTRRDCIRLRNLPAGAQVPDILTFLGEFSQYIVYQGVHMVLTAQGEPSGESFIQLDSEEAATLTTMHKHRRPMTFAN-KKRIIDVIQCSGEDMS 552          
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Match: A0A433UEI1 (RRM domain-containing protein (Fragment) OS=Elysia chlorotica OX=188477 GN=EGW08_000041 PE=4 SV=1)

HSP 1 Score: 464.537 bits (1194), Expect = 4.543e-148
Identity = 249/563 (44.23%), Postives = 351/563 (62.34%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGI-PSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTS--TNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIA 2310
            +V F + TAGK  D+LG DE  IV I   +YD   +K + ++Q+ V  +   + E       +LTEDC  ET L++ L   A PL   L++  + L + G+ P      FCL+TDGQA +R     E  + NI L +Y  ++ F DLRKEF++FY  +    +  M    N+   D    YG+ QC +M +I+ ++ +DG  + + E + +     I  K++YVSD +VVRARGLPWQ++D DI +FF+GLNI KGG+AL LS  GRRNGEALIRF+S EHRD+AL++HKHH+GQRYIEVY A+G+DFI VAGG+  EA+ FL R     QT+IRMRGLP+T+T  Q+LEFFT    +  V  GE+GILFV++ DGR+TGDAFV+F  EE + +ALK HRE +G+RYIELFKST AEV QV+N  + P                     LI+ LP  +P+I    +      R  +R++ +P    V DI+ FL ++ Q+I YQG H++Y + G  +GEA IQ+ SE+AA L    +H++ +S ++ KK ++DV  CSG D++
Sbjct:    7 IVCFFVSTAGKNGDELGADEEQIVQIVYLLYDQNNNKVVDVQQHFVKPQPNELAET------VLTEDCKTETGLDEELVKQAPPLDHALEEFDRFLSAKGVHPDHGGRSFCLLTDGQAHLRQCVQHECCKKNISLPSY--FYRFYDLRKEFKKFYKTDVVSSIKFMTDYLNL-DEDGSVEYGVRQCQEMAKILTRLVNDGHTFGDAEIINERLEGGICTKNEYVSDGLVVRARGLPWQSSDQDIARFFKGLNIAKGGVALCLSPQGRRNGEALIRFESEEHRDLALKRHKHHIGQRYIEVYKASGKDFINVAGGNNSEAQAFLSR---GGQTIIRMRGLPFTSTTQQVLEFFTREPNSSAVLDGEEGILFVHYPDGRSTGDAFVLFPTEEESVKALKKHREMMGSRYIELFKSTTAEVQQVLNRSMDPRNPEQPDSSVPA---------LIAQLPAGVPIIPQSLITS-GTRRDCIRLRNLPSAAQVTDILTFLGEFSQFIIYQGVHMVYTATGDASGEAFIQLDSEEAATLTALNRHRRPMSFAN-KKRVIDVIQCSGDDMS 546          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Match: esrp1 (epithelial splicing regulatory protein 1 [Source:NCBI gene;Acc:103047742])

HSP 1 Score: 380.563 bits (976), Expect = 7.236e-118
Identity = 219/572 (38.29%), Postives = 319/572 (55.77%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDG--FKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQI-PMINSP-------CLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDI 2307
            LV+F   T G   + LG+DET  V +   + + +  K  ++ +  V           K ++  ++E+C   + +     + A PL   L   ++ L S  I + +   FCL TDGQ  +R   HPE +  N+ L   + +F+F DLRKEF++ +  E   K L L  M    N+  + S   +   + H+M  I + +  +     +   E V + + +    K + + D  V+RARGLPWQ++D D+ +FFRGLNI KGG AL L+  GRRNGEAL+RF+S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG + E   FL R    +Q ++RMRGLP+TATA Q+L+FF S +CPV    +GILFV   DGR TGDAFV+F  EE AE ALK H+E +G RYIELF+ST AEV QV+N                       +  LI + P+ I P++  P        +  +   R  +R++G+P + +V DI+ FL +Y   I   G H++ N  G+P+G+A IQM S + A L  +  HK+     S K+  V+V  CS  ++
Sbjct:    8 LVLFFTTTCGASGELLGSDETEAVQLVWQVLNLVTKKPGRVNEVLV-----------KPESLCVSEECVEVSGVTTEALSSAAPLEEALNQFNERLCS-EINTDAANSFCLCTDGQLHLRQVLHPEASNKNVLLP--ECFFSFFDLRKEFKKCFPSEADHKELDLKFMTDYLNLSEDSSDQVFTAQKIHQMSSIAQALISEPTCHVFSCPEKVNEKFETGTCSKMERIDDNTVIRARGLPWQSSDQDVARFFRGLNIAKGGAALCLNAQGRRNGEALVRFESEEHRDLALQRHKHHMGSRYIEVYKATGEDFLKIAGGTSNEVANFLSR---ENQVIVRMRGLPFTATAEQVLQFF-SPSCPVTDDGEGILFVRFPDGRPTGDAFVLFSCEEYAENALKKHKEILGKRYIELFRSTAAEVQQVLNKYS--------------------SAPLIPVAPSPILPIVPQPTFVPSPAAIAAVVGTRDCLRLRGLPYDASVQDILLFLGEYTADIRPHGVHMVLNQQGRPSGDAFIQMRSAERAHLAAQRCHKR-----SMKERYVEVFPCSAQEM 536          

HSP 2 Score: 98.9821 bits (245), Expect = 1.050e-20
Identity = 64/219 (29.22%), Postives = 108/219 (49.32%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEV------FLQRITKPS--------------QTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAE-EALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V+VR RGLP+ AT   + +FF     +  +  GI  V    GR  G+A + F   E+ + AL+KHK  +G+RYIE++ +T  +  QV    +    +       L  + +P+              +  +R+RGLPY A+   IL F       +     G+  V ++ GR +GDAF+   + E A   A + H+ ++  RY+E+F  +  E+N V+
Sbjct:  324 NQVIVRMRGLPFTATAEQVLQFFSPSCPVTDDGEGILFVRFPDGRPTGDAFVLFSCEEYAENALKKHKEILGKRYIELFRSTAAEVQQVLNKYSSAPLIPVAPSPILPIVPQPTFVPSPAAIAAVVGTRDCLRLRGLPYDASVQDILLFLGEYTADIR--PHGVHMVLNQQGRPSGDAFIQMRSAERAHLAAQRCHKRSMKERYVEVFPCSAQEMNIVL 540          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:103029380])

HSP 1 Score: 357.836 bits (917), Expect = 1.202e-109
Identity = 213/561 (37.97%), Postives = 309/561 (55.08%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQE-CNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACS 2295
            LVVF   TAG     LG+DE  I+L+   I D  + K  K++Q  +           K     LT+ C  ET L       A  L  VL+   ++ +S  + ++ +  + L  DG   +R A HPE ++ N+ L   + ++ F+DL++EF R        K L L  M++  C   +N+     G+ +   M+ II+ +  + +  K+   E V   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF + EHRDMAL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT   +L F    + PV  G +G+LFV   DGR TGDAFV+F  E+ A+ ALK H++ +G RYIELF+ST AEV QV+N                LI+TL     +   +    P I +         R  VR++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+++     K   V+V  CS
Sbjct:    8 LVVFFGATAGANGGKLGSDEREIILLVWQIVDLHEKKVGKIQQRLI-----------KPDTLELTDQCKEETGLTVEELGKADHLDTVLQQFQQA-VSAEVKALGRSSYTLCVDGPLLIRQALHPEASKKNLVLP--ECFYQFVDLKREFHRCCPNAGPVKDLSLPSMLEYLCLPAVNEQLA--GVREVKSMMMIIQHILAEPYNHKFSSLEPVKYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALERHKHHMGSRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQVIIRMRGLPFTATQQDVLGFL-GPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY----------MSTPLISTLPPPPMVPVPVLAAPPFITTAST------RDCVRLRGLPYTAGIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMM-----KDRYVEVFQCS 527          

HSP 2 Score: 94.3597 bits (233), Expect = 2.595e-19
Identity = 63/217 (29.03%), Postives = 110/217 (50.69%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRGLN-IEKGGIALVLSKV--GRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV------------------AGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V++R RGLP+ AT  D+  F    + +  G   L+  K   GR  G+A + F   ++   AL+KHK  +G+RYIE++ +T  +  QV                         A  F+   T  ++  +R+RGLPYTA    ILEF       ++    G+  V ++ GR +GDAF+  ++ + A   + K H++ + +RY+E+F+ +  E++ V+
Sbjct:  323 NQVIIRMRGLPFTATQQDVLGFLGPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPLISTLPPPPMVPVPVLAAPPFI--TTASTRDCVRLRGLPYTAGIEDILEFMGEHT--IDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMMKDRYVEVFQCSTEEMSFVL 535          

HSP 3 Score: 55.0694 bits (131), Expect = 3.754e-7
Identity = 34/96 (35.42%), Postives = 52/96 (54.17%), Query Frame = 1
Query: 1297 VSDEVVVRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
             S    VR RGLP+ A   DI +F     ++I+  G+ +VL++ GR +G+A I+ KS +   M  +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  444 ASTRDCVRLRGLPYTAGIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMMKDRYVEVFQCSTEEMSFVLMGGT 539          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:103029380])

HSP 1 Score: 357.451 bits (916), Expect = 2.192e-109
Identity = 213/561 (37.97%), Postives = 309/561 (55.08%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQE-CNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACS 2295
            LVVF   TAG     LG+DE  I+L+   I D  + K  K++Q  +           K     LT+ C  ET L       A  L  VL+   ++ +S  + ++ +  + L  DG   +R A HPE ++ N+ L   + ++ F+DL++EF R        K L L  M++  C   +N+     G+ +   M+ II+ +  + +  K+   E V   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF + EHRDMAL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT   +L F    + PV  G +G+LFV   DGR TGDAFV+F  E+ A+ ALK H++ +G RYIELF+ST AEV QV+N                LI+TL     +   +    P I +         R  VR++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+++     K   V+V  CS
Sbjct:    8 LVVFFGATAGANGGKLGSDEREIILLVWQIVDLHEKKVGKIQQRLI-----------KPDTLELTDQCKEETGLTVEELGKADHLDTVLQQFQQA-VSAEVKALGRSSYTLCVDGPLLIRQALHPEASKKNLVLP--ECFYQFVDLKREFHRCCPNAGPVKDLSLPSMLEYLCLPAVNEQLA--GVREVKSMMMIIQHILAEPYNHKFSSLEPVKYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALERHKHHMGSRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQVIIRMRGLPFTATQQDVLGFL-GPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY----------MSTPLISTLPPPPMVPVPVLAAPPFITTAST------RDCVRLRGLPYTAGIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMM-----KDRYVEVFQCS 527          

HSP 2 Score: 94.3597 bits (233), Expect = 2.535e-19
Identity = 63/217 (29.03%), Postives = 110/217 (50.69%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRGLN-IEKGGIALVLSKV--GRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV------------------AGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V++R RGLP+ AT  D+  F    + +  G   L+  K   GR  G+A + F   ++   AL+KHK  +G+RYIE++ +T  +  QV                         A  F+   T  ++  +R+RGLPYTA    ILEF       ++    G+  V ++ GR +GDAF+  ++ + A   + K H++ + +RY+E+F+ +  E++ V+
Sbjct:  323 NQVIIRMRGLPFTATQQDVLGFLGPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPLISTLPPPPMVPVPVLAAPPFI--TTASTRDCVRLRGLPYTAGIEDILEFMGEHT--IDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMMKDRYVEVFQCSTEEMSFVL 535          

HSP 3 Score: 55.0694 bits (131), Expect = 3.966e-7
Identity = 34/96 (35.42%), Postives = 52/96 (54.17%), Query Frame = 1
Query: 1297 VSDEVVVRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
             S    VR RGLP+ A   DI +F     ++I+  G+ +VL++ GR +G+A I+ KS +   M  +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  444 ASTRDCVRLRGLPYTAGIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMMKDRYVEVFQCSTEEMSFVLMGGT 539          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:103029380])

HSP 1 Score: 357.451 bits (916), Expect = 2.192e-109
Identity = 213/561 (37.97%), Postives = 309/561 (55.08%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQE-CNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACS 2295
            LVVF   TAG     LG+DE  I+L+   I D  + K  K++Q  +           K     LT+ C  ET L       A  L  VL+   ++ +S  + ++ +  + L  DG   +R A HPE ++ N+ L   + ++ F+DL++EF R        K L L  M++  C   +N+     G+ +   M+ II+ +  + +  K+   E V   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF + EHRDMAL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT   +L F    + PV  G +G+LFV   DGR TGDAFV+F  E+ A+ ALK H++ +G RYIELF+ST AEV QV+N                LI+TL     +   +    P I +         R  VR++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+++     K   V+V  CS
Sbjct:    8 LVVFFGATAGANGGKLGSDEREIILLVWQIVDLHEKKVGKIQQRLI-----------KPDTLELTDQCKEETGLTVEELGKADHLDTVLQQFQQA-VSAEVKALGRSSYTLCVDGPLLIRQALHPEASKKNLVLP--ECFYQFVDLKREFHRCCPNAGPVKDLSLPSMLEYLCLPAVNEQLA--GVREVKSMMMIIQHILAEPYNHKFSSLEPVKYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALERHKHHMGSRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQVIIRMRGLPFTATQQDVLGFL-GPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY----------MSTPLISTLPPPPMVPVPVLAAPPFITTAST------RDCVRLRGLPYTAGIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMM-----KDRYVEVFQCS 527          

HSP 2 Score: 94.3597 bits (233), Expect = 2.535e-19
Identity = 63/217 (29.03%), Postives = 110/217 (50.69%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRGLN-IEKGGIALVLSKV--GRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV------------------AGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V++R RGLP+ AT  D+  F    + +  G   L+  K   GR  G+A + F   ++   AL+KHK  +G+RYIE++ +T  +  QV                         A  F+   T  ++  +R+RGLPYTA    ILEF       ++    G+  V ++ GR +GDAF+  ++ + A   + K H++ + +RY+E+F+ +  E++ V+
Sbjct:  323 NQVIIRMRGLPFTATQQDVLGFLGPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPLISTLPPPPMVPVPVLAAPPFI--TTASTRDCVRLRGLPYTAGIEDILEFMGEHT--IDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMMKDRYVEVFQCSTEEMSFVL 535          

HSP 3 Score: 55.0694 bits (131), Expect = 3.966e-7
Identity = 34/96 (35.42%), Postives = 52/96 (54.17%), Query Frame = 1
Query: 1297 VSDEVVVRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
             S    VR RGLP+ A   DI +F     ++I+  G+ +VL++ GR +G+A I+ KS +   M  +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  444 ASTRDCVRLRGLPYTAGIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMMKDRYVEVFQCSTEEMSFVLMGGT 539          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:103029380])

HSP 1 Score: 357.451 bits (916), Expect = 4.205e-109
Identity = 213/561 (37.97%), Postives = 309/561 (55.08%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE---KSLVLDEMIQE-CNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACS 2295
            LVVF   TAG     LG+DE  I+L+   I D  + K  K++Q  +           K     LT+ C  ET L       A  L  VL+   ++ +S  + ++ +  + L  DG   +R A HPE ++ N+ L   + ++ F+DL++EF R        K L L  M++  C   +N+     G+ +   M+ II+ +  + +  K+   E V   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF + EHRDMAL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT   +L F    + PV  G +G+LFV   DGR TGDAFV+F  E+ A+ ALK H++ +G RYIELF+ST AEV QV+N                LI+TL     +   +    P I +         R  VR++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+++     K   V+V  CS
Sbjct:    8 LVVFFGATAGANGGKLGSDEREIILLVWQIVDLHEKKVGKIQQRLI-----------KPDTLELTDQCKEETGLTVEELGKADHLDTVLQQFQQA-VSAEVKALGRSSYTLCVDGPLLIRQALHPEASKKNLVLP--ECFYQFVDLKREFHRCCPNAGPVKDLSLPSMLEYLCLPAVNEQLA--GVREVKSMMMIIQHILAEPYNHKFSSLEPVKYKFESGACSKTEAVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFINSEHRDMALERHKHHMGSRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQVIIRMRGLPFTATQQDVLGFL-GPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY----------MSTPLISTLPPPPMVPVPVLAAPPFITTAST------RDCVRLRGLPYTAGIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMM-----KDRYVEVFQCS 527          

HSP 2 Score: 94.3597 bits (233), Expect = 3.014e-19
Identity = 63/217 (29.03%), Postives = 110/217 (50.69%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRGLN-IEKGGIALVLSKV--GRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV------------------AGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V++R RGLP+ AT  D+  F    + +  G   L+  K   GR  G+A + F   ++   AL+KHK  +G+RYIE++ +T  +  QV                         A  F+   T  ++  +R+RGLPYTA    ILEF       ++    G+  V ++ GR +GDAF+  ++ + A   + K H++ + +RY+E+F+ +  E++ V+
Sbjct:  323 NQVIIRMRGLPFTATQQDVLGFLGPDSPVTDGTEGLLFVKFPDGRPTGDAFVLFACEQYAQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPLISTLPPPPMVPVPVLAAPPFI--TTASTRDCVRLRGLPYTAGIEDILEFMGEHT--IDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMMKDRYVEVFQCSTEEMSFVL 535          

HSP 3 Score: 55.0694 bits (131), Expect = 4.347e-7
Identity = 34/96 (35.42%), Postives = 52/96 (54.17%), Query Frame = 1
Query: 1297 VSDEVVVRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
             S    VR RGLP+ A   DI +F     ++I+  G+ +VL++ GR +G+A I+ KS +   M  +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  444 ASTRDCVRLRGLPYTAGIEDILEFMGEHTIDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVSQKCHKKMMKDRYVEVFQCSTEEMSFVLMGGT 539          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Sea Lamprey
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:572992])

HSP 1 Score: 301.597 bits (771), Expect = 1.829e-90
Identity = 171/473 (36.15%), Postives = 253/473 (53.49%), Query Frame = 1
Query:  952 DFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPN-QIPMINSPCLDQLNLG-----------------RTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIA 2310
             FCL  DG   +R   HPE +R  + L +   + ++ DLRKEF +  +  + + +  M     +   D+   +G  +   M +II  +    +  K+   E V   + S      + V  + VVR RGLPWQ++D DI  FF+GLNI KGGIAL L+ +GRRNGEAL+  +  + RD+AL +HKHHMG RYIEVY ++  +F ++A G + E   FL R     Q ++RMRGLP+ A  + +L FF +  CPV  G  G+LFV H DGR TGDAFV+F  EE A  AL  HR  +G RYIELF+ST AE+ QV+N V                    M+  L+ ++P    P    P      L                  R  VR++G+P   ++ +I++FL ++   I  QG H+++N  G+P+G+A IQM   + AAL  +  H++ +     ++  V+V ACS  +++
Sbjct:   17 SFCLCVDGPLFLRQVCHPEASRKGVSLPHC--FNSYYDLRKEFAKCCSTSQEINIWTMADALGV-TRDADAEFGAAEAAAMSKIILALAASPYNHKFSNPEEVMSQFESGNCSHYNSVHGDTVVRVRGLPWQSSDQDIALFFKGLNIAKGGIALCLNPLGRRNGEALVMLQDEQQRDLALSRHKHHMGSRYIEVYRSSAEEFSKIAVGASSEVSQFLAR---EGQVIVRMRGLPFAAAPDDVLAFFGAA-CPVTAGRQGLLFVRHPDGRPTGDAFVLFAGEECAAAALAKHRHMLGKRYIELFRSTAAELQQVLNRV--------------------MSTPLLPVVPALPSPFPGGPLCPSGPLTPGGPLTPGGPLTPGGAQRDCVRLRGLPYSASIEEILDFLGEFAGDIRPQGVHMVFNQQGRPSGDAFIQMRGAERAALAAQRCHRRSL-----RERYVEVFACSADEMS 457          

HSP 2 Score: 97.0561 bits (240), Expect = 7.389e-21
Identity = 66/232 (28.45%), Postives = 103/232 (44.40%), Query Frame = 1
Query: 1306 EVVVRARGLPWQATDSDINKFFRG---LNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV--------------------AGGD----------TEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGED----GILFVNHKDGRATGDAFVIFEN-EEVAEEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            +V+VR RGLP+ A   D+  FF     +   + G+  V    GR  G+A + F   E    AL KH+H +G+RYIE++ +T  +  QV                     GG                          +  +R+RGLPY+A+  +IL+F        EF  D    G+  V ++ GR +GDAF+     E  A  A + HR ++  RY+E+F  +  E++ V+
Sbjct:  235 QVIVRMRGLPFAAAPDDVLAFFGAACPVTAGRQGLLFVRHPDGRPTGDAFVLFAGEECAAAALAKHRHMLGKRYIELFRSTAAELQQVLNRVMSTPLLPVVPALPSPFPGGPLCPSGPLTPGGPLTPGGPLTPGGAQRDCVRLRGLPYSASIEEILDFLG------EFAGDIRPQGVHMVFNQQGRPSGDAFIQMRGAERAALAAQRCHRRSLRERYVEVFACSADEMSVVL 460          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Sea Lamprey
Match: HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1 [Source:HGNC Symbol;Acc:HGNC:5041])

HSP 1 Score: 124.79 bits (312), Expect = 2.601e-30
Identity = 74/198 (37.37%), Postives = 111/198 (56.06%), Query Frame = 1
Query: 1288 SDYVSDEVVVRARGLPWQATDSDINKFFRGLNI--EKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEV 1875
            +D V +  VVR RGLPW  +  ++ KF  G  I     G+    S+ GR +GEA +  +S E  D AL +   +MG RYIEV+ +   +   V     ++  V L   +  ++  +R+RGLP++ +  +I +FFT     +E   +GI       GR+TG+AFV F ++E AE+AL  H+E IG+RYIE+FKS   EV
Sbjct:    4 ADEVVEGFVVRLRGLPWSCSSEEVIKFLSGCAIVNSADGVHFTNSREGRPSGEAFVELESEEDLDRALERDHKNMGHRYIEVFRSKLSELNWVL---NQQNPVALPE-SGEAEGCVRLRGLPFSCSKEEIAQFFTG----LEIVPNGITLPVDYQGRSTGEAFVQFASQEAAEKALGKHKERIGHRYIEVFKSNRGEV 193          

HSP 2 Score: 90.5077 bits (223), Expect = 3.856e-19
Identity = 58/209 (27.75%), Postives = 102/209 (48.80%), Query Frame = 1
Query: 1624 LIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLIS 2250
            ++R+RGLP++ ++ ++++F +   C +    DG+ F N ++GR +G+AFV  E+EE  + AL+   +N+G+RYIE+F+S  +E+N V+N                                 Q P+     L +       VR++G+P   +  +I  F    G  I   G  +  +  G+  GEA +Q  S++AA   +  KHK+ I 
Sbjct:   12 VVRLRGLPWSCSSEEVIKFLSG--CAIVNSADGVHFTNSREGRPSGEAFVELESEEDLDRALERDHKNMGHRYIEVFRSKLSELNWVLNQ--------------------------------QNPV----ALPESGEAEGCVRLRGLPFSCSKEEIAQFFT--GLEIVPNGITLPVDYQGRSTGEAFVQFASQEAAEKAL-GKHKERIG 179          

HSP 3 Score: 54.299 bits (129), Expect = 1.081e-7
Identity = 30/73 (41.10%), Postives = 41/73 (56.16%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYM 1533
            V  RGLP++AT+ DIN FF  LN  +  + +     GR  GE  + F S E    A+ K K HM  RYIE+++
Sbjct:  301 VHMRGLPFRATELDINNFFTPLNPVR--VNIEYDGSGRPTGECDVEFASHEDAVTAMAKDKAHMQHRYIELFL 371          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Nematostella
Match: EDO47286 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMK7])

HSP 1 Score: 278.1 bits (710), Expect = 6.067e-85
Identity = 141/350 (40.29%), Postives = 215/350 (61.43%), Query Frame = 1
Query: 1297 VSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIP---------MINSPCLDQLNLG---RTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIA 2310
            V D+ V+RARGLPWQA+D D+  FFRGLNI +GGIA  L+  GRRNGEA IRF++ +HRD+ALR+HK H+G RYIEVY A+ +DF+++  G +  A      ++  ++ +IRMRGLP++  A  ++ FF   + PV  GE GIL V  ++G+ATGDAFV+FE EE    ALK HRE +G+RY+ELF+S+ +EV QV++S                ++   M    +++LPN +P          +  P     N G   +  +R++G+P   TV D+++FL+++  Y++  G H++YN+ G+P+G+A +Q++S   AA      HK  +      +  ++V  CS  DI+
Sbjct:    7 VLDDTVLRARGLPWQASDQDVANFFRGLNIPRGGIAFCLNMQGRRNGEAFIRFENGDHRDLALRRHKMHLGTRYIEVYKASAQDFLRIVRGMSIAANF----VSTNAEVIIRMRGLPFSTKAADVVRFF-GDDVPVYRGEGGILMVRGRNGKATGDAFVLFETEEHGRAALKKHREVLGSRYVELFRSSQSEVQQVLSS----------------LSLFMMGVPPLAMLPNPLPQHPPFHPPMFLPGPVPYAANGGSNAKDCLRLRGLPFSATVQDVLDFLKEHAAYVAPGGVHMVYNTQGRPSGDAYVQLLSPDFAAAAANELHKHHMG-----ERYIEVFPCSNSDIS 330          

HSP 2 Score: 101.679 bits (252), Expect = 3.310e-23
Identity = 74/279 (26.52%), Postives = 135/279 (48.39%), Query Frame = 1
Query: 1186 HKMLEIIRKMTDDGFKWKETETVAKHYYSAIVR----KSDYVSD--EVVVRARGLPWQATDSDINKFFRGLNIE----KGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVF------LQRITKP--------------------------SQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFV-IFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNS 1893
            H+ L + R     G ++ E    +   +  IVR     +++VS   EV++R RGLP+    +D+ +FF G ++     +GGI +V  + G+  G+A + F++ EH   AL+KH+  +G RY+E++ ++  +  QV         +F      L  +  P                          ++  +R+RGLP++AT   +L+F       V  G  G+  V +  GR +GDA+V +   +  A  A + H+ ++G RYIE+F  + ++++ V+ S
Sbjct:   64 HRDLALRRHKMHLGTRYIEVYKASAQDFLRIVRGMSIAANFVSTNAEVIIRMRGLPFSTKAADVVRFF-GDDVPVYRGEGGILMVRGRNGKATGDAFVLFETEEHGRAALKKHREVLGSRYVELFRSSQSEVQQV----LSSLSLFMMGVPPLAMLPNPLPQHPPFHPPMFLPGPVPYAANGGSNAKDCLRLRGLPFSATVQDVLDFLKEHAAYVAPG--GVHMVYNTQGRPSGDAYVQLLSPDFAAAAANELHKHHMGERYIEVFPCSNSDISAVIAS 335          

HSP 3 Score: 56.9954 bits (136), Expect = 1.874e-8
Identity = 32/90 (35.56%), Postives = 49/90 (54.44%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFR--GLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            +R RGLP+ AT  D+  F +     +  GG+ +V +  GR +G+A ++  S +    A  + HKHHMG+RYIEV+  +  D   V    T
Sbjct:  248 LRLRGLPFSATVQDVLDFLKEHAAYVAPGGVHMVYNTQGRPSGDAYVQLLSPDFAAAAANELHKHHMGERYIEVFPCSNSDISAVIASST 337          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Nematostella
Match: EDO37823 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEP3])

HSP 1 Score: 140.969 bits (354), Expect = 2.065e-36
Identity = 75/204 (36.76%), Postives = 118/204 (57.84%), Query Frame = 1
Query: 1297 VSDEVVVRARGLPWQATDSDINKFFRGLNIEKG---GIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPS----QTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            + +E VVRARGLPW AT  DI  FF+  NI  G   G+       GR +GE  ++F S +  + AL  +  HMG+RYIEV+ +             EE E  ++R+  PS    + ++++RGLPY  +  +I +FFT     +E   +GI     ++G+ TG+ FV F + E+A +A++ H+E IG+RYIE+FKS+ +++  V+
Sbjct:    1 MDNECVVRARGLPWSATPEDIQNFFKDCNIVGGPQNGVHFTFGIDGRPSGECFVQFVSEKDVEKALEMNNEHMGKRYIEVFRSK-----------AEEMEWVIKRMGPPSDRDQEAVVKLRGLPYGCSKEEIAQFFTG----LEIVPNGITITLDEEGKTTGEGFVEFASPEIAGQAMQKHKEKIGHRYIEIFKSSKSDIKYVL 189          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Nematostella
Match: EDO47487 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLV0])

HSP 1 Score: 61.6178 bits (148), Expect = 1.464e-9
Identity = 35/78 (44.87%), Postives = 48/78 (61.54%), Query Frame = 1
Query: 1630 RMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKST 1863
            +MRGLP+ A    ILEFF+    PV      I FV +K G+ +G AFV F ++   E+ALK +++ +  RYIELFK T
Sbjct:  256 KMRGLPFKAKDKHILEFFSPLK-PV-----AIRFVMNKKGQPSGCAFVDFSSKSDLEKALKRNKDYLQGRYIELFKDT 327          

HSP 2 Score: 58.9214 bits (141), Expect = 9.848e-9
Identity = 32/91 (35.16%), Postives = 53/91 (58.24%), Query Frame = 1
Query: 1312 VVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEA 1584
              + RGLP++A D  I +FF  L  +   I  V++K G+ +G A + F S+   + AL+++K ++  RYIE++  T RDF     GD E++
Sbjct:  254 TCKMRGLPFKAKDKHILEFFSPL--KPVAIRFVMNKKGQPSGCAFVDFSSKSDLEKALKRNKDYLQGRYIELFKDTNRDFDNNKQGDGEKS 342          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Nematostella
Match: EDO47282 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMK2])

HSP 1 Score: 53.9138 bits (128), Expect = 3.030e-9
Identity = 26/73 (35.62%), Postives = 44/73 (60.27%), Query Frame = 1
Query: 1309 VVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEV 1527
            VV++ +GLP++AT  DI  FF GL++ +  I L  +K G+ +G +   F   +    A+ +   +MG+RYIE+
Sbjct:    3 VVIKMKGLPFEATSRDIQMFFDGLSLREKDIHLAANKDGKASGISFAVFNVDDDARKAMYRTGKYMGKRYIEL 75          

HSP 2 Score: 51.6026 bits (122), Expect = 2.272e-8
Identity = 27/76 (35.53%), Postives = 44/76 (57.89%), Query Frame = 1
Query: 1624 LIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIEL 1851
            +I+M+GLP+ AT+  I  FF      +   E  I    +KDG+A+G +F +F  ++ A +A+    + +G RYIEL
Sbjct:    4 VIKMKGLPFEATSRDIQMFFDG----LSLREKDIHLAANKDGKASGISFAVFNVDDDARKAMYRTGKYMGKRYIEL 75          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Nematostella
Match: EDO47283 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMK3])

HSP 1 Score: 53.5286 bits (127), Expect = 7.077e-9
Identity = 30/84 (35.71%), Postives = 45/84 (53.57%), Query Frame = 1
Query: 1612 PSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRA----TGDAFVIFENEEVAEEALKSHRENIGNRYIEL 1851
             + T++RM GLP+ ++   + +FF             I  + HK G+     TG AFV+F++   A +ALK  R  IG+RYIEL
Sbjct:   13 ATSTIVRMFGLPFESSKRDLYKFFNGLKIA------SIDLLKHKSGKNQGKNTGVAFVVFKSNNDASKALKMDRSYIGHRYIEL 90          

HSP 2 Score: 50.447 bits (119), Expect = 8.445e-8
Identity = 29/83 (34.94%), Postives = 45/83 (54.22%), Query Frame = 1
Query: 1291 DYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGE----ALIRFKSREHRDMALRKHKHHMGQRYIEV 1527
            D  +   +VR  GLP++++  D+ KFF GL I    I L+  K G+  G+    A + FKS      AL+  + ++G RYIE+
Sbjct:   10 DQEATSTIVRMFGLPFESSKRDLYKFFNGLKI--ASIDLLKHKSGKNQGKNTGVAFVVFKSNNDASKALKMDRSYIGHRYIEL 90          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:101173047])

HSP 1 Score: 364.385 bits (934), Expect = 9.087e-112
Identity = 217/563 (38.54%), Postives = 312/563 (55.42%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRF---YNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ--IPMINS-PCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACS 2295
            LVVF   TAG     LG+DE  I+L+   I D  + K  KL  Y V           K  +  LT+ C  ET L       A+PL  VL+   +S +S  + S+ +  F L+ +    +R   HPE ++ N+ L   + +F+F+DLRKEF +        +   L  M++   +    S    G+ +   M+++   +  + +  K+   ETV   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF   EHRD+AL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT+ ++L F    + PV  G +G+LFV + DGR TGDAFV+F  EE  + ALK H++ +G RYIELF+ST AEV QV+N                      M+  LIS LP    +P++ S P L      R  VR++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+ +     K   V+V  CS
Sbjct:    8 LVVFFGATAGANGGKLGSDEREIILLVWQIVDLHEKKVGKLHSYYV-----------KPDSLELTDQCKEETGLTVEDIIKAEPLDKVLQQFQQS-VSSEVKSLGRSSFTLLVNSPLVIRQVLHPEASKKNLVLP--ECFFSFVDLRKEFHKCCPNAGPAQKQTLVSMLEYVGL-PAASEQLTGVKEVRSMVQLTLCILAEPYCHKFTCVETVNYKFDSGACCKTEPVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFIDSEHRDLALERHKHHMGCRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQVIIRMRGLPFTATSQEVLSFLGPES-PVTDGAEGLLFVKYPDGRPTGDAFVLFSCEEYVQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY--------------------MSTPLISTLPASPIVPVLASQPFLPAATSTRDCVRLRGLPYTAGIEDILEFMGEHTVDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTM-----KDRYVEVFQCS 526          

HSP 2 Score: 101.293 bits (251), Expect = 2.226e-21
Identity = 65/215 (30.23%), Postives = 111/215 (51.63%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRGLN-IEKGGIALVLSKV--GRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGG----------------DTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V++R RGLP+ AT  ++  F    + +  G   L+  K   GR  G+A + F   E+   AL+KHK  +G+RYIE++ +T  +  QV                       ++ FL   T  ++  +R+RGLPYTA    ILEF       V+    G+  V ++ GR +GDAF+  ++ + A   A K H++ + +RY+E+F+ +  E++ V+
Sbjct:  323 NQVIIRMRGLPFTATSQEVLSFLGPESPVTDGAEGLLFVKYPDGRPTGDAFVLFSCEEYVQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPLISTLPASPIVPVLASQPFLPAATS-TRDCVRLRGLPYTAGIEDILEFMGEHT--VDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTMKDRYVEVFQCSTEEMSIVL 534          

HSP 3 Score: 56.6102 bits (135), Expect = 1.464e-7
Identity = 33/90 (36.67%), Postives = 51/90 (56.67%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            VR RGLP+ A   DI +F     ++I+  G+ +VL++ GR +G+A I+ KS +   M  +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  449 VRLRGLPYTAGIEDILEFMGEHTVDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTMKDRYVEVFQCSTEEMSIVLMGGT 538          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:101173047])

HSP 1 Score: 363.229 bits (931), Expect = 1.305e-111
Identity = 217/563 (38.54%), Postives = 312/563 (55.42%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRF---YNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ--IPMINS-PCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACS 2295
            LVVF   TAG     LG+DE  I+L+   I D  + K  KL  Y V           K  +  LT+ C  ET L       A+PL  VL+   +S +S  + S+ +  F L+ +    +R   HPE ++ N+ L   + +F+F+DLRKEF +        +   L  M++   +    S    G+ +   M+++   +  + +  K+   ETV   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF   EHRD+AL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT+ ++L F    + PV  G +G+LFV + DGR TGDAFV+F  EE  + ALK H++ +G RYIELF+ST AEV QV+N                      M+  LIS LP    +P++ S P L      R  VR++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+ +     K   V+V  CS
Sbjct:    8 LVVFFGATAGANGGKLGSDEREIILLVWQIVDLHEKKVGKLHSYYV-----------KPDSLELTDQCKEETGLTVEDIIKAEPLDKVLQQFQQS-VSSEVKSLGRSSFTLLVNSPLVIRQVLHPEASKKNLVLP--ECFFSFVDLRKEFHKCCPNAGPAQKQTLVSMLEYVGL-PAASEQLTGVKEVRSMVQLTLCILAEPYCHKFTCVETVNYKFDSGACCKTEPVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFIDSEHRDLALERHKHHMGCRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQVIIRMRGLPFTATSQEVLSFLGPES-PVTDGAEGLLFVKYPDGRPTGDAFVLFSCEEYVQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY--------------------MSTPLISTLPASPIVPVLASQPFLPAATSTRDCVRLRGLPYTAGIEDILEFMGEHTVDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTM-----KDRYVEVFQCS 526          

HSP 2 Score: 99.7525 bits (247), Expect = 5.671e-21
Identity = 65/215 (30.23%), Postives = 111/215 (51.63%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRGLN-IEKGGIALVLSKV--GRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTE----------------EAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V++R RGLP+ AT  ++  F    + +  G   L+  K   GR  G+A + F   E+   AL+KHK  +G+RYIE++ +T  +  QV                       ++ FL   T  ++  +R+RGLPYTA    ILEF       V+    G+  V ++ GR +GDAF+  ++ + A   A K H++ + +RY+E+F+ +  E++ V+
Sbjct:  323 NQVIIRMRGLPFTATSQEVLSFLGPESPVTDGAEGLLFVKYPDGRPTGDAFVLFSCEEYVQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPLISTLPASPIVPVLASQPFLPAATS-TRDCVRLRGLPYTAGIEDILEFMGEHT--VDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTMKDRYVEVFQCSTEEMSIVL 534          

HSP 3 Score: 55.8398 bits (133), Expect = 2.518e-7
Identity = 33/90 (36.67%), Postives = 51/90 (56.67%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            VR RGLP+ A   DI +F     ++I+  G+ +VL++ GR +G+A I+ KS +   M  +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  449 VRLRGLPYTAGIEDILEFMGEHTVDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTMKDRYVEVFQCSTEEMSIVLMGGT 538          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:101173047])

HSP 1 Score: 363.614 bits (932), Expect = 1.515e-111
Identity = 217/563 (38.54%), Postives = 312/563 (55.42%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRF---YNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ--IPMINS-PCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACS 2295
            LVVF   TAG     LG+DE  I+L+   I D  + K  KL  Y V           K  +  LT+ C  ET L       A+PL  VL+   +S +S  + S+ +  F L+ +    +R   HPE ++ N+ L   + +F+F+DLRKEF +        +   L  M++   +    S    G+ +   M+++   +  + +  K+   ETV   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF   EHRD+AL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT+ ++L F    + PV  G +G+LFV + DGR TGDAFV+F  EE  + ALK H++ +G RYIELF+ST AEV QV+N                      M+  LIS LP    +P++ S P L      R  VR++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+ +     K   V+V  CS
Sbjct:    8 LVVFFGATAGANGGKLGSDEREIILLVWQIVDLHEKKVGKLHSYYV-----------KPDSLELTDQCKEETGLTVEDIIKAEPLDKVLQQFQQS-VSSEVKSLGRSSFTLLVNSPLVIRQVLHPEASKKNLVLP--ECFFSFVDLRKEFHKCCPNAGPAQKQTLVSMLEYVGL-PAASEQLTGVKEVRSMVQLTLCILAEPYCHKFTCVETVNYKFDSGACCKTEPVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFIDSEHRDLALERHKHHMGCRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQVIIRMRGLPFTATSQEVLSFLGPES-PVTDGAEGLLFVKYPDGRPTGDAFVLFSCEEYVQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY--------------------MSTPLISTLPASPIVPVLASQPFLPAATSTRDCVRLRGLPYTAGIEDILEFMGEHTVDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTM-----KDRYVEVFQCS 526          

HSP 2 Score: 100.138 bits (248), Expect = 4.085e-21
Identity = 65/215 (30.23%), Postives = 111/215 (51.63%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRGLN-IEKGGIALVLSKV--GRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGG----------------DTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V++R RGLP+ AT  ++  F    + +  G   L+  K   GR  G+A + F   E+   AL+KHK  +G+RYIE++ +T  +  QV                       ++ FL   T  ++  +R+RGLPYTA    ILEF       V+    G+  V ++ GR +GDAF+  ++ + A   A K H++ + +RY+E+F+ +  E++ V+
Sbjct:  323 NQVIIRMRGLPFTATSQEVLSFLGPESPVTDGAEGLLFVKYPDGRPTGDAFVLFSCEEYVQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPLISTLPASPIVPVLASQPFLPAATS-TRDCVRLRGLPYTAGIEDILEFMGEHT--VDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTMKDRYVEVFQCSTEEMSIVL 534          

HSP 3 Score: 56.225 bits (134), Expect = 1.948e-7
Identity = 33/90 (36.67%), Postives = 51/90 (56.67%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            VR RGLP+ A   DI +F     ++I+  G+ +VL++ GR +G+A I+ KS +   M  +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  449 VRLRGLPYTAGIEDILEFMGEHTVDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTMKDRYVEVFQCSTEEMSIVLMGGT 538          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Match: esrp2 (epithelial splicing regulatory protein 2 [Source:NCBI gene;Acc:101173047])

HSP 1 Score: 363.229 bits (931), Expect = 3.042e-111
Identity = 217/563 (38.54%), Postives = 312/563 (55.42%), Query Frame = 1
Query:  631 LVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRF---YNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQ--IPMINS-PCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACS 2295
            LVVF   TAG     LG+DE  I+L+   I D  + K  KL  Y V           K  +  LT+ C  ET L       A+PL  VL+   +S +S  + S+ +  F L+ +    +R   HPE ++ N+ L   + +F+F+DLRKEF +        +   L  M++   +    S    G+ +   M+++   +  + +  K+   ETV   + S    K++ V  E V+RARGLPWQ++D DI +FF+GLNI KGG+AL L+  GRRNGEAL+RF   EHRD+AL +HKHHMG RYIEVY ATG +F+++AGG + E   FL   +K +Q +IRMRGLP+TAT+ ++L F    + PV  G +G+LFV + DGR TGDAFV+F  EE  + ALK H++ +G RYIELF+ST AEV QV+N                      M+  LIS LP    +P++ S P L      R  VR++G+P    + DI+ F+ ++   I   G H++ N  G+P+G+A IQM S   A +V +  HK+ +     K   V+V  CS
Sbjct:    8 LVVFFGATAGANGGKLGSDEREIILLVWQIVDLHEKKVGKLHSYYV-----------KPDSLELTDQCKEETGLTVEDIIKAEPLDKVLQQFQQS-VSSEVKSLGRSSFTLLVNSPLVIRQVLHPEASKKNLVLP--ECFFSFVDLRKEFHKCCPNAGPAQKQTLVSMLEYVGL-PAASEQLTGVKEVRSMVQLTLCILAEPYCHKFTCVETVNYKFDSGACCKTEPVDSETVIRARGLPWQSSDQDIARFFKGLNIAKGGVALCLNAQGRRNGEALVRFIDSEHRDLALERHKHHMGCRYIEVYKATGEEFLKIAGGTSNEVAQFL---SKENQVIIRMRGLPFTATSQEVLSFLGPES-PVTDGAEGLLFVKYPDGRPTGDAFVLFSCEEYVQNALKKHKQILGKRYIELFRSTAAEVQQVLNRY--------------------MSTPLISTLPASPIVPVLASQPFLPAATSTRDCVRLRGLPYTAGIEDILEFMGEHTVDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTM-----KDRYVEVFQCS 526          

HSP 2 Score: 100.138 bits (248), Expect = 4.257e-21
Identity = 65/215 (30.23%), Postives = 111/215 (51.63%), Query Frame = 1
Query: 1303 DEVVVRARGLPWQATDSDINKFFRGLN-IEKGGIALVLSKV--GRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTE----------------EAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVA-EEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++V++R RGLP+ AT  ++  F    + +  G   L+  K   GR  G+A + F   E+   AL+KHK  +G+RYIE++ +T  +  QV                       ++ FL   T  ++  +R+RGLPYTA    ILEF       V+    G+  V ++ GR +GDAF+  ++ + A   A K H++ + +RY+E+F+ +  E++ V+
Sbjct:  323 NQVIIRMRGLPFTATSQEVLSFLGPESPVTDGAEGLLFVKYPDGRPTGDAFVLFSCEEYVQNALKKHKQILGKRYIELFRSTAAEVQQVLNRYMSTPLISTLPASPIVPVLASQPFLPAATS-TRDCVRLRGLPYTAGIEDILEFMGEHT--VDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTMKDRYVEVFQCSTEEMSIVL 534          

HSP 3 Score: 56.225 bits (134), Expect = 1.895e-7
Identity = 33/90 (36.67%), Postives = 51/90 (56.67%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFF--RGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRK-HKHHMGQRYIEVYMATGRDFIQVAGGDT 1575
            VR RGLP+ A   DI +F     ++I+  G+ +VL++ GR +G+A I+ KS +   M  +K HK  M  RY+EV+  +  +   V  G T
Sbjct:  449 VRLRGLPYTAGIEDILEFMGEHTVDIKPHGVHMVLNQQGRPSGDAFIQMKSADRAFMVAQKCHKKTMKDRYVEVFQCSTEEMSIVLMGGT 538          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Match: esrp1 (epithelial splicing regulatory protein 1 [Source:NCBI gene;Acc:101168983])

HSP 1 Score: 355.91 bits (912), Expect = 2.315e-108
Identity = 220/592 (37.16%), Postives = 315/592 (53.21%), Query Frame = 1
Query:  619 MTG---ILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQ---PLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKE--KSLVLDEMIQECNIFIN-----------DSGGNYGIIQCHKMLEIIRKMTDDGF--KWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTN-----CPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSP-CLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKS-MVDVSACSGLDIA 2310
            MTG    LVVF   TAG   + LG+DE  +V +   + D       ++ +  +       TEE   ++ +  ++   + +  D +FT       LS     L   + + G    +   +CL TDGQ  +R   HPE A  NI +   D +++F DLRKEF++ +     K+  +  M +   I +            D G    + Q   M  I+  +  +     +   E V + + S    K + V D  V+RARGLPWQ++D DI +FFRGLNI KGG AL L+  GRRNGEAL+RF S EHRD+AL++HKHHMG RYIEVY ATG DF+++AGG T E  +FL R     Q ++RMRGLP+TAT  Q+L FF+  +     CPV  G+DGILFV + DGR TGDAFV+F  EE A  AL+ H+E +G RYIELFKST AEV QV+N        P                 L+S+LP+ + ++  P C+      R  +R++G+P   ++ DI+ FL ++   I   G H++ N  G+P+G+  IQM S + A    +  HK ++    G  S  V+V  CS  ++ 
Sbjct:    1 MTGQVDYLVVFFTTTAGACGELLGSDEKELVQLVWQLVDLKNKTLGRVNELLIKPDLSDFTEENVKEDVVDNKET-EKGSGGDCIFTVTSIDTALSMFDLQLKNEVNNAG----AGTSWCLCTDGQLHIRQVIHPEAASKNILVP--DCFYSFFDLRKEFKKHFPSSDLKASNVGSMAESLGIPVESPPEWEPLGTQDPGTIVPVQQVQLMASIVLALLSEHSCNAFSNPERVNEKFESGTCSKKEKVCDNTVIRARGLPWQSSDQDIARFFRGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGNRYIEVYKATGEDFLKIAGGTTNEVAMFLSR---EDQIIVRMRGLPFTATYEQVLAFFSPKDGLNETCPVSGGKDGILFVRYPDGRPTGDAFVLFSCEEHALCALRKHKEILGKRYIELFKSTAAEVQQVLNRYSSTPLIP------------VAPAPLLSMLPS-VSLLPPPGCV------RDCLRLRGLPYTASIEDILAFLGEFTHDIRPHGVHMVLNQQGRPSGDCFIQMSSPECALQASQQLHKHVMPSQRGANSRYVEVFPCSAEEMG 563          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Match: SMESG000023329.1 (SMESG000023329.1)

HSP 1 Score: 1586.62 bits (4107), Expect = 0.000e+0
Identity = 798/799 (99.87%), Postives = 799/799 (100.00%), Query Frame = 1
Query:  619 MTGILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVXXXXXXXXXXXXXXXIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIAQFSGFIQTPNQAQTQIQMQNALYQLQILQKQFVSSGIAINQVPYPSYWPCIPTSHXXXXXXXXXXXXXXXHILHSPLMGGYFYNIPVPGQGPRMPAGLQTPSMVNPLNPCNNSYLQSPLSHSQPPGLVFSASNSPTTFYIPNMGVLQTHNNCQEYAFVVLKNLPKDITLEEIISIFEPVIQQGINITDIKVGITSDNSATGEAFVAFLNRLDAEKSVIECQSRYVRNAPVDISLL 3015
            MTGILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVLIPAPSPPAIDDPSLIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIAQFSGFIQTPNQ+QTQIQMQNALYQLQILQKQFVSSGIAINQVPYPSYWPCIPTSHNTALNNILNNTAPANHILHSPLMGGYFYNIPVPGQGPRMPAGLQTPSMVNPLNPCNNSYLQSPLSHSQPPGLVFSASNSPTTFYIPNMGVLQTHNNCQEYAFVVLKNLPKDITLEEIISIFEPVIQQGINITDIKVGITSDNSATGEAFVAFLNRLDAEKSVIECQSRYVRNAPVDISLL
Sbjct:    1 MTGILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNSVLIPAPSPPAIDDPSLIATLTMNGNLISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQYISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKKSMVDVSACSGLDIAQFSGFIQTPNQSQTQIQMQNALYQLQILQKQFVSSGIAINQVPYPSYWPCIPTSHNTALNNILNNTAPANHILHSPLMGGYFYNIPVPGQGPRMPAGLQTPSMVNPLNPCNNSYLQSPLSHSQPPGLVFSASNSPTTFYIPNMGVLQTHNNCQEYAFVVLKNLPKDITLEEIISIFEPVIQQGINITDIKVGITSDNSATGEAFVAFLNRLDAEKSVIECQSRYVRNAPVDISLL 799          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Match: SMESG000023329.1 (SMESG000023329.1)

HSP 1 Score: 737.258 bits (1902), Expect = 0.000e+0
Identity = 351/351 (100.00%), Postives = 351/351 (100.00%), Query Frame = 1
Query:  619 MTGILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQI 1671
            MTGILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQI
Sbjct:    1 MTGILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQI 351          

HSP 2 Score: 62.3882 bits (150), Expect = 6.492e-10
Identity = 34/89 (38.20%), Postives = 54/89 (60.67%), Query Frame = 1
Query: 1618 QTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQV 1884
            + ++R RGLP+ AT + I +FF   N  +E G  GI  V  K GR  G+A + F++ E  + AL+ H+ ++G RYIE++ +T  +  QV
Sbjct:  230 EVVVRARGLPWQATDSDINKFFRGLN--IEKG--GIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQV 314          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Match: SMESG000044612.1 (SMESG000044612.1)

HSP 1 Score: 223.016 bits (567), Expect = 1.444e-61
Identity = 149/434 (34.33%), Postives = 229/434 (52.76%), Query Frame = 1
Query:  628 ILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSI--KLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCD-----FCLVTDGQAPMRLAFHPEIARNNIDLTNYDY-YFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIF-INDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHM---GQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNS 1893
            IL+ FH+VT G Q +DLG DET+I+ +   + D   +++I  KL   Q S    S+ +   N +++       E  + D L + +   +F L+D    + S    ++   D        V  G  P+R   H E    NI+L NY Y Y+N  D    F       K   LDE+    N   I   GG    I C+ M   I ++T  G  +     +   Y   +   +D +  ++V+  + + ++   + I  FFRGLNI  GGIA+++S+ GRR+ + LI+F+ +  RD+AL + KHHM     R+I + +   R+F+++AG + E  +V+L++I    Q LIR++GLPYT T  +IL FF S +  V+F  +GI  V    G   GDAFVIFENE VA++A       IGNRY+E+F STP E+NQV+++
Sbjct:   45 ILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQAS----SLLDPSANPDKIHISVPARE--MTDLLSSPSSHSTFKLQDALNEIDSFINQNVLFSDDQTIEVIPVILGHLPLRSVLHRETRFRNINLNNYWYHYYNLFDEVSIF----TSSKCQNLDEI---SNFLQIEKPGGTTMSIICY-MSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEILNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISA 463          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Match: SMESG000044612.1 (SMESG000044612.1)

HSP 1 Score: 198.749 bits (504), Expect = 4.589e-53
Identity = 149/486 (30.66%), Postives = 229/486 (47.12%), Query Frame = 1
Query:  628 ILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSI--KLEQYQVSGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSLISIGIPSISQCD-----FCLVTDGQAPMRLAFHPEIARNNIDLTNYDY-YFNFIDLRKEFQRFYNKEKSLVLDEMIQECNIF-INDSGGNYGIIQCHKMLEIIRKMTDDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHM---GQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQI----------------------------------------------------LEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVMNS 1893
            IL+ FH+VT G Q +DLG DET+I+ +   + D   +++I  KL   Q S    S+ +   N +++       E  + D L + +   +F L+D    + S    ++   D        V  G  P+R   H E    NI+L NY Y Y+N  D    F       K   LDE+    N   I   GG    I C+ M   I ++T  G  +     +   Y   +   +D +  ++V+  + + ++   + I  FFRGLNI  GGIA+++S+ GRR+ + LI+F+ +  RD+AL + KHHM     R+I + +   R+F+++AG + E  +V+L++I    Q LIR++GLPYT T  +I                                                    L FF S +  V+F  +GI  V    G   GDAFVIFENE VA++A       IGNRY+E+F STP E+NQV+++
Sbjct:   45 ILMAFHLVTCGLQGNDLGRDETAILQVGFQLIDLSNNQAIGGKLILLQAS----SLLDPSANPDKIHISVPARE--MTDLLSSPSSHSTFKLQDALNEIDSFINQNVLFSDDQTIEVIPVILGHLPLRSVLHRETRFRNINLNNYWYHYYNLFDEVSIF----TSSKCQNLDEI---SNFLQIEKPGGTTMSIICY-MSNAILQLTQLGHLFHSKHVIKNGYKPIVFHVNDEIEPDIVLMIKPIDYKTPINQIIPFFRGLNIADGGIAVIMSE-GRRSNKILIKFEDKVQRDIALLRDKHHMEPGNSRFITISVHDSREFMKIAGYENESVKVYLEQIETQDQILIRIKGLPYTVTKPEIVSELNFLYFMSSLKVLLIFVYIIMCISAHPQIHRADPGLNYLWLDKRNEIIQLNFFKSNDVEVQFSHNGIFLVQKSSGELNGDAFVIFENEGVAQKAKNLKGMTIGNRYMEIFYSTPPEMNQVISA 515          
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Match: SMESG000009582.1 (SMESG000009582.1)

HSP 1 Score: 104.375 bits (259), Expect = 9.452e-24
Identity = 68/192 (35.42%), Postives = 102/192 (53.12%), Query Frame = 1
Query: 1315 VRARGLPWQATDSDINKFFRGLNI-EKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPAEVNQVM 1887
            ++ RGLP+ AT++DI  F  GL I  + GI + L+  GR +GEAL++  +  + +     +  +MG R+IEV+ AT +D+        EE      R+     T +R+RGLPY  T   I  FF      +    DG+  +   D   TG+AFV F   E A  AL+ H + I +RYIE++KS+  EV + M
Sbjct:    5 LKLRGLPYSATETDILTFLSGLPIWTESGILITLNDDGRPSGEALVKLDTEINLNDLTEYNGKYMGTRFIEVFPATQKDWF------GEE-----MRMKMSDMTYVRLRGLPYDVTKEDIFIFFNR----LMISRDGVGLLVGPDDVPTGEAFVQFMTREDANLALQRHNQCIRSRYIEIYKSSLTEVYRAM 181          

HSP 2 Score: 64.6994 bits (156), Expect = 1.401e-10
Identity = 31/81 (38.27%), Postives = 48/81 (59.26%), Query Frame = 1
Query: 1297 VSDEVVVRARGLPWQATDSDINKFFRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRYIEVYMAT 1539
            +SD   VR RGLP+  T  DI  FF  L I + G+ L++       GEA ++F +RE  ++AL++H   +  RYIE+Y ++
Sbjct:   93 MSDMTYVRLRGLPYDVTKEDIFIFFNRLMISRDGVGLLVGPDDVPTGEAFVQFMTREDANLALQRHNQCIRSRYIEIYKSS 173          

HSP 3 Score: 55.8398 bits (133), Expect = 8.499e-8
Identity = 34/81 (41.98%), Postives = 46/81 (56.79%), Query Frame = 1
Query: 1627 IRMRGLPYTATANQILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSHRENIGNRYIELFKSTPA 1869
            I MRGLPY+AT   + +FF+    P+   E  I      DG+ATG+A   F  EE A +A++  R  +  RYIELF+ T A
Sbjct:  269 IHMRGLPYSATDKDVQDFFS----PIRVAEVKIQI--GPDGKATGEAEADFFTEEDAMKAMEKDRCKMSWRYIELFRGTSA 343          
The following BLAST results are available for this feature:
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ESRP11.734e-11738.58epithelial splicing regulatory protein 1 [Source:H... [more]
ESRP13.208e-11738.58epithelial splicing regulatory protein 1 [Source:H... [more]
ESRP16.294e-11738.38epithelial splicing regulatory protein 1 [Source:H... [more]
ESRP11.033e-11638.38epithelial splicing regulatory protein 1 [Source:H... [more]
ESRP11.614e-11638.38epithelial splicing regulatory protein 1 [Source:H... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sym-28.832e-7436.56RNA-binding protein sym-2 [Source:UniProtKB/Swiss... [more]
sym-26.623e-4039.04RNA-binding protein sym-2 [Source:UniProtKB/Swiss... [more]
sym-26.623e-4039.04RNA-binding protein sym-2 [Source:UniProtKB/Swiss... [more]
hrpf-11.519e-2533.00HnRNP F homolog [Source:UniProtKB/TrEMBL;Acc:H2KZ... [more]
hrpf-12.546e-2433.00HnRNP F homolog [Source:UniProtKB/TrEMBL;Acc:H2KZ... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fus4.071e-11438.39gene:FBgn0023441 transcript:FBtr0302330[more]
fus3.447e-11036.56gene:FBgn0023441 transcript:FBtr0087345[more]
fus1.849e-10936.56gene:FBgn0023441 transcript:FBtr0087343[more]
fus1.849e-10936.56gene:FBgn0023441 transcript:FBtr0087344[more]
fus1.849e-10936.56gene:FBgn0023441 transcript:FBtr0087346[more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
esrp12.359e-12139.54epithelial splicing regulatory protein 1 [Source:N... [more]
esrp22.290e-11233.03epithelial splicing regulatory protein 2 [Source:N... [more]
esrp22.290e-11233.03epithelial splicing regulatory protein 2 [Source:N... [more]
esrp22.406e-11233.16epithelial splicing regulatory protein 2 [Source:N... [more]
esrp22.406e-11233.16epithelial splicing regulatory protein 2 [Source:N... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
atf14.081e-11237.85activating transcription factor 1 [Source:Xenbase;... [more]
atf16.910e-11038.01activating transcription factor 1 [Source:Xenbase;... [more]
atf12.971e-10937.83activating transcription factor 1 [Source:Xenbase;... [more]
atf11.754e-10737.59activating transcription factor 1 [Source:Xenbase;... [more]
atf13.520e-10637.66activating transcription factor 1 [Source:Xenbase;... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Esrp11.286e-11938.94epithelial splicing regulatory protein 1 [Source:M... [more]
Esrp13.092e-11938.73epithelial splicing regulatory protein 1 [Source:M... [more]
Esrp14.852e-11938.73epithelial splicing regulatory protein 1 [Source:M... [more]
Esrp14.964e-11938.73epithelial splicing regulatory protein 1 [Source:M... [more]
Esrp21.418e-11336.96epithelial splicing regulatory protein 2 [Source:M... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A1L1G1|ESRP1_DANRE1.781e-12039.54Epithelial splicing regulatory protein 1 OS=Danio ... [more]
sp|B2RYD2|ESRP1_RAT5.955e-11939.26Epithelial splicing regulatory protein 1 OS=Rattus... [more]
sp|Q3US41|ESRP1_MOUSE8.785e-11738.73Epithelial splicing regulatory protein 1 OS=Mus mu... [more]
sp|Q6NXG1|ESRP1_HUMAN3.023e-11638.38Epithelial splicing regulatory protein 1 OS=Homo s... [more]
sp|Q8K0G8|ESRP2_MOUSE9.916e-11336.96Epithelial splicing regulatory protein 2 OS=Mus mu... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267EB470.000e+050.97Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267FI410.000e+050.97Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A210PZV82.252e-15037.44Epithelial splicing regulatory protein 1 OS=Mizuho... [more]
A0A2T7NHQ02.296e-15045.07RRM domain-containing protein OS=Pomacea canalicul... [more]
A0A433UEI14.543e-14844.23RRM domain-containing protein (Fragment) OS=Elysia... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
esrp17.236e-11838.29epithelial splicing regulatory protein 1 [Source:N... [more]
esrp21.202e-10937.97epithelial splicing regulatory protein 2 [Source:N... [more]
esrp22.192e-10937.97epithelial splicing regulatory protein 2 [Source:N... [more]
esrp22.192e-10937.97epithelial splicing regulatory protein 2 [Source:N... [more]
esrp24.205e-10937.97epithelial splicing regulatory protein 2 [Source:N... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
esrp21.829e-9036.15epithelial splicing regulatory protein 2 [Source:N... [more]
HNRNPH12.601e-3037.37heterogeneous nuclear ribonucleoprotein H1 [Source... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO472866.067e-8540.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO378232.065e-3636.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO474871.464e-944.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO472823.030e-935.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO472837.077e-935.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
esrp29.087e-11238.54epithelial splicing regulatory protein 2 [Source:N... [more]
esrp21.305e-11138.54epithelial splicing regulatory protein 2 [Source:N... [more]
esrp21.515e-11138.54epithelial splicing regulatory protein 2 [Source:N... [more]
esrp23.042e-11138.54epithelial splicing regulatory protein 2 [Source:N... [more]
esrp12.315e-10837.16epithelial splicing regulatory protein 1 [Source:N... [more]
back to top
BLAST of Epithelial splicing regulatory protein 1/2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000023329.10.000e+099.87SMESG000023329.1[more]
SMESG000023329.16.492e-10100.00SMESG000023329.1[more]
SMESG000044612.11.444e-6134.33SMESG000044612.1[more]
SMESG000044612.14.589e-5330.66SMESG000044612.1[more]
SMESG000009582.19.452e-2435.42SMESG000009582.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022187 ID=SMED30022187|Name=Epithelial splicing regulatory protein 1/2|organism=Schmidtea mediterranea sexual|type=transcript|length=3215bp
GTTTCAATCTTAACAACTGAATACGTGATAATAATAATCGCAATAACATT
TTGAGTAAAAAAATAACAATTGATTTTATTGATATTCTGCCATGTCTACA
AGGACAGCTTATCACCCACAGGTATGCACCACAAACTCGACCACAAAACA
ACAACAGCACATGTAACTTTACATTGCAATTCTAAAAAATCAACAAAACC
AACCGTTGTGTCCCTGTCTAAATGTCTCCATAGCGATTGCACCTTAAAAT
CTAATCGGGCTAGATTTTTCTCATAAAAATTCATACGGCACACCGGTTTT
CTAAAATATCAATTTTGCACAAAATCGATTTTATTTTATTTTGAGCAATA
TCCAACCAAAACCCCGCAAATTGGGATTGTGTTTGTTTGCATTCAATTTG
TCAGTTGTTGCATTGTTGCGCGTGTCTGTGTGTTTGTGCACACACAATAG
CAATTTTCTTATACACACACACACTCTCACGCGAATGCATAACAACTGAT
TAGTGGAGTTTACACAGAAACAATCGACACTTATTATTTTTTGTTGTTGA
AATCATTCCCGAATCTTCAATTCCGTATAAAAGAAAATTGCAATAGCAAT
TGTTGAAACTGTTACATAATGACGGGAATTTTAGTGGTTTTCCACATTGT
TACTGCTGGCAAGCAAGCCGATGATTTGGGAACTGATGAAACCTCAATTG
TGCTCATTACGATTGCCATTTATGATACAATACAGTCGAAGAGCATAAAA
TTGGAACAGTATCAAGTGTCAGGGAGACACGAGTCGATGACAGAGGAGGA
GAAAAATCAAAACCGATTGCTAACAGAAGACTGCTGCCTCGAAACCAATT
TGAATGATTCTCTGTTTACCGGAGCACAGCCGTTGTCATTTGTGTTGAAA
GATCTCCATAAATCGTTGATTAGCATCGGAATTCCGTCGATTAGTCAATG
CGATTTTTGCCTGGTTACCGACGGACAAGCACCGATGCGATTGGCTTTTC
ATCCGGAAATCGCTCGCAACAATATTGATTTGACGAATTATGATTATTAT
TTCAATTTTATTGATTTACGCAAAGAGTTTCAAAGATTTTATAATAAGGA
GAAATCTTTAGTTCTCGATGAAATGATTCAAGAATGTAATATTTTCATAA
ATGATAGTGGTGGAAATTATGGTATCATTCAATGTCACAAAATGCTTGAG
ATCATACGCAAAATGACAGATGATGGGTTTAAATGGAAAGAAACTGAAAC
AGTCGCAAAGCATTATTATTCTGCAATTGTAAGAAAATCAGATTATGTCA
GCGACGAAGTTGTAGTAAGAGCTAGAGGTTTACCATGGCAAGCTACAGAC
AGCGATATAAATAAATTCTTTCGTGGACTAAACATAGAGAAAGGAGGAAT
AGCATTAGTTCTTAGTAAAGTTGGTCGAAGAAATGGTGAAGCGTTGATTC
GATTCAAAAGTCGTGAGCATCGAGATATGGCTTTGAGAAAACATAAACAT
CACATGGGTCAAAGATATATTGAAGTTTATATGGCTACTGGACGAGATTT
TATACAAGTTGCAGGAGGGGACACAGAAGAAGCAGAGGTGTTTCTACAAA
GAATAACAAAACCTTCACAGACTTTAATTAGAATGCGAGGGCTACCATAT
ACAGCGACAGCAAATCAAATATTGGAATTTTTTACCTCAACTAATTGCCC
AGTTGAATTTGGTGAAGATGGAATTCTTTTCGTCAATCACAAAGATGGGA
GAGCCACTGGAGATGCGTTTGTGATTTTTGAAAATGAAGAAGTCGCCGAA
GAAGCCTTGAAAAGTCACAGAGAAAATATTGGCAATCGGTATATAGAACT
TTTCAAGTCAACACCTGCAGAAGTAAATCAAGTCATGAATTCCGTACTAA
TTCCAGCTCCTTCGCCCCCTGCCATTGATGACCCGTCCCTGATTGCCACC
CTCACAATGAATGGCAATCTGATATCGTTGTTACCGAATCAAATTCCTAT
GATTAATTCCCCTTGTCTCGATCAGCTTAATTTAGGTCGAACTTTTGTCA
GAATAAAAGGAATGCCATTAGAAACTACGGTGGCAGATATCATTAATTTT
CTCGAACAGTATGGACAATACATATCATACCAAGGTGCTCACATTATTTA
CAATAGTATGGGTCAACCTGCTGGTGAGGCAATTATTCAGATGATCTCAG
AGCAAGCAGCGGCTTTAGTGGTTGAAGCGAAACACAAACAATTGATCAGT
ATCAGCTCAGGAAAAAAGTCTATGGTCGACGTGTCGGCCTGTTCTGGTTT
GGATATTGCACAATTTAGCGGTTTCATTCAAACCCCTAATCAAGCTCAAA
CACAAATCCAAATGCAGAATGCTCTCTATCAACTTCAAATTCTACAGAAG
CAATTTGTGTCTTCAGGAATAGCTATAAACCAAGTTCCATATCCAAGTTA
TTGGCCTTGTATTCCCACAAGCCACAATACAGCATTAAATAACATATTAA
ACAATACAGCCCCAGCAAACCATATTCTGCATTCTCCATTAATGGGAGGA
TATTTCTACAATATTCCAGTTCCAGGACAAGGTCCTAGAATGCCAGCTGG
TCTTCAAACACCGTCGATGGTTAACCCGTTAAACCCTTGCAATAATAGTT
ATTTACAATCACCATTGTCTCATTCCCAGCCTCCAGGATTGGTGTTTTCA
GCAAGTAATTCACCTACAACTTTTTATATTCCAAATATGGGAGTTCTGCA
AACTCACAACAATTGTCAGGAGTATGCTTTTGTGGTTCTCAAAAACTTAC
CGAAAGATATAACTCTTGAAGAAATAATCAGCATATTTGAGCCAGTTATC
CAGCAAGGCATAAACATAACCGATATCAAGGTTGGAATAACATCCGACAA
TTCGGCGACCGGAGAGGCATTCGTAGCTTTTCTTAATCGATTAGACGCGG
AAAAGTCTGTGATAGAATGCCAGAGCCGCTACGTTCGCAATGCGCCAGTA
GACATTTCTTTGCTCTAGTTTAATTTTTGAATCACTGATTTTATTTGTAT
TTATTATATGCACTCAATTTTAGAATGAAATATTATCAAATATCTTGATA
TCTAAAATCACCAATTGATAAAAACTTTTGAACATTGAAACTTTTCTTTG
AATATTTAGTCTTTTATGAGTATTTCTTAAAAATAATTTCAATATATTGT
GTTTATTAAAAACAA
back to top

protein sequence of SMED30022187-orf-1

>SMED30022187-orf-1 ID=SMED30022187-orf-1|Name=SMED30022187-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=800bp
MTGILVVFHIVTAGKQADDLGTDETSIVLITIAIYDTIQSKSIKLEQYQV
SGRHESMTEEEKNQNRLLTEDCCLETNLNDSLFTGAQPLSFVLKDLHKSL
ISIGIPSISQCDFCLVTDGQAPMRLAFHPEIARNNIDLTNYDYYFNFIDL
RKEFQRFYNKEKSLVLDEMIQECNIFINDSGGNYGIIQCHKMLEIIRKMT
DDGFKWKETETVAKHYYSAIVRKSDYVSDEVVVRARGLPWQATDSDINKF
FRGLNIEKGGIALVLSKVGRRNGEALIRFKSREHRDMALRKHKHHMGQRY
IEVYMATGRDFIQVAGGDTEEAEVFLQRITKPSQTLIRMRGLPYTATANQ
ILEFFTSTNCPVEFGEDGILFVNHKDGRATGDAFVIFENEEVAEEALKSH
RENIGNRYIELFKSTPAEVNQVMNSVLIPAPSPPAIDDPSLIATLTMNGN
LISLLPNQIPMINSPCLDQLNLGRTFVRIKGMPLETTVADIINFLEQYGQ
YISYQGAHIIYNSMGQPAGEAIIQMISEQAAALVVEAKHKQLISISSGKK
SMVDVSACSGLDIAQFSGFIQTPNQAQTQIQMQNALYQLQILQKQFVSSG
IAINQVPYPSYWPCIPTSHNTALNNILNNTAPANHILHSPLMGGYFYNIP
VPGQGPRMPAGLQTPSMVNPLNPCNNSYLQSPLSHSQPPGLVFSASNSPT
TFYIPNMGVLQTHNNCQEYAFVVLKNLPKDITLEEIISIFEPVIQQGINI
TDIKVGITSDNSATGEAFVAFLNRLDAEKSVIECQSRYVRNAPVDISLL*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0003676nucleic acid binding
GO:0000166nucleotide binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000099neuron
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR036397RNaseH_sf
IPR035979RBD_domain_sf
IPR000504RRM_dom
IPR012677Nucleotide-bd_a/b_plait_sf
IPR012337RNaseH-like_sf
IPR013809ENTH
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000504RNA recognition motif domainSMARTSM00360rrm1_1coord: 336..412
e-value: 6.4E-7
score: 39.0
coord: 232..304
e-value: 8.8E-4
score: 28.6
coord: 476..546
e-value: 0.048
score: 18.3
coord: 721..797
e-value: 0.012
score: 23.6
IPR000504RNA recognition motif domainPFAMPF00076RRM_1coord: 338..409
e-value: 1.5E-4
score: 21.5
coord: 722..793
e-value: 5.9E-6
score: 26.0
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 720..799
score: 10.104
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 335..416
score: 10.565
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 231..308
score: 8.706
IPR036397Ribonuclease H superfamilyGENE3DG3DSA:3.30.420.10coord: 8..231
e-value: 6.9E-19
score: 70.1
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 316..428
e-value: 2.9E-30
score: 106.5
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 232..309
e-value: 3.3E-22
score: 80.3
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 472..566
e-value: 6.9E-14
score: 53.5
coord: 715..799
e-value: 6.3E-10
score: 40.8
NoneNo IPR availablePANTHERPTHR13976:SF37EPITHELIAL SPLICING REGULATORY PROTEIN 1coord: 209..559
NoneNo IPR availablePANTHERPTHR13976HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATEDcoord: 209..559
NoneNo IPR availableCDDcd12508RRM2_ESRPs_Fusillicoord: 334..414
e-value: 1.39054E-40
score: 141.29
NoneNo IPR availableCDDcd00590RRM_SFcoord: 722..797
e-value: 1.03968E-8
score: 50.3813
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 227..314
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 331..424
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 469..543
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 714..797