Tubulin polyglutamylase TTLL7

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEK 1775
            +TANV GT+FEIV+ +++ +GF    DE  +T  LIW DS + QE+I+EL++YQRINHF GM EI RKDFL +  +KM K RP DY + P+TW+FP E      Y+KE KK  K+K FI+KPANGAMG GI L    D + S +  IVQEYI+KP L++GYK D RIY+L+T CDPL+ F+Y +GLVR+ TEKY   ++  +  ++ HLTNYSVNK N ++ R   E+ GSK+S+      F      +    W  I ++VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDILLD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+++L  QK +AQRRL       ++ P   ++  ++R  +E+RK++L + L +V+   SRE  ENRH+GN+ R++PP+DK + + Y  LL  +F  F         +    + Q+ L + +  + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ITANVAGTKFEIVRLVIDEMGFMKTPDED-ETSNLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYTFVPRTWIFPAEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIK-WFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQKAEAQRRLYGQNSIKRLLPG-SSDWEQQRHQLERRKEELKERLAQVRKQISREEHENRHMGNYRRIYPPEDKALLEKYENLLAVAFQTF--------LSGRAASFQRELNNPL-KRMKEEDILDLLEQCEIDDEKLMGK 521          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEK 1775
            +TANV GT+FEIV+ +++ +GF    DE  +T  LIW DS + QE+I+EL++YQRINHF GM EI RKDFL +  +KM K RP DY + P+TW+FP E      Y+KE KK  K+K FI+KPANGAMG GI L    D + S +  IVQEYI+KP L++GYK D RIY+L+T CDPL+ F+Y +GLVR+ TEKY   ++  +  ++ HLTNYSVNK N ++ R   E+ GSK+S+      F      +    W  I ++VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDILLD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+++L  QK +AQRRL       ++ P   ++  ++R  +E+RK++L + L +V+   SRE  ENRH+GN+ R++PP+DK + + Y  LL  +F  F         +    + Q+ L + +  + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ITANVAGTKFEIVRLVIDEMGFMKTPDED-ETSNLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYTFVPRTWIFPAEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIK-WFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQKAEAQRRLYGQNSIKRLLPG-SSDWEQQRHQLERRKEELKERLAQVRKQISREEHENRHMGNYRRIYPPEDKALLEKYENLLAVAFQTF--------LSGRAASFQRELNNPL-KRMKEEDILDLLEQCEIDDEKLMGK 521          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEK 1775
            +TANV GT+FEIV+ +++ +GF    DE  +T  LIW DS + QE+I+EL++YQRINHF GM EI RKDFL +  +KM K RP DY + P+TW+FP E      Y+KE KK  K+K FI+KPANGAMG GI L    D + S +  IVQEYI+KP L++GYK D RIY+L+T CDPL+ F+Y +GLVR+ TEKY   ++  +  ++ HLTNYSVNK N ++ R   E+ GSK+S+      F      +    W  I ++VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDILLD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+++L  QK +AQRRL       ++ P   ++  ++R  +E+RK++L + L +V+   SRE  ENRH+GN+ R++PP+DK + + Y  LL  +F  F         +    + Q+ L + +  + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ITANVAGTKFEIVRLVIDEMGFMKTPDED-ETSNLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYTFVPRTWIFPAEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIK-WFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQKAEAQRRLYGQNSIKRLLPG-SSDWEQQRHQLERRKEELKERLAQVRKQISREEHENRHMGNYRRIYPPEDKALLEKYENLLAVAFQTF--------LSGRAASFQRELNNPL-KRMKEEDILDLLEQCEIDDEKLMGK 521          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFS-HFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFS 2786
            IR+PG++D E++ ++  I  NW++ +  VA+YWL  L++ K+ K++ IV+ ++  ++   +K   D+    + R+ ++V+NRLLW+RG GL  CF     SW+ IF+ S +++ PL+L  C R+V+LC  C+L+VY+++
Sbjct:  693 IRFPGKSDAESELLIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVLDIVKTSIRTVLPRIWKV-PDVEEVNLYRIFNRVFNRLLWSRGQGLWNCFCDSGSSWESIFNKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYA 830          

Query:  528 MQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEK 1775
            M K RP DY + P+TW+FP E      Y+KE KK  K+K FI+KPANGAMG GI L    D + S +  IVQEYI+KP L++GYK D RIY+L+T CDPL+ F+Y +GLVR+ TEKY   ++  +  ++ HLTNYSVNK N ++ R   E+ GSK+S+      F      +    W  I ++VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDILLD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+++L  QK +AQRRL       ++ P   ++  ++R  +E+RK++L + L +V+   SRE  ENRH+GN+ R++PP+DK + + Y  LL  +F  F         +    + Q+ L + +  + +EEDI++ ++QCE ++  L+ K
Sbjct:    1 MIKSRPLDYTFVPRTWIFPAEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIK-WFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQKAEAQRRLYGQNSIKRLLPG-SSDWEQQRHQLERRKEELKERLAQVRKQISREEHENRHMGNYRRIYPPEDKALLEKYENLLAVAFQTF--------LSGRAASFQRELNNPL-KRMKEEDILDLLEQCEIDDEKLMGK 405          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQ 1373
            +  N++  R+E V++  +  GF    ++   T Y  WTD  +S ER+ E+KSYQ+INHF GM EI RKD L +  S+M K+ PKD+ +FP+TW  P +    +  ++   +  K K +I KP +G  G GI +      IK  E  I Q YI KP ++DG+K D RIYVL+T CDPLR F+Y EGL R +T  Y+      +D I  HLTNYS+NK +SN++R   ++    +   S  + +    + N + +W+ I D+++KTL+   P + HNY  C      N  S  FEILGFDILLD  L PWLLEVN SPSF  D  LD++VK  LL DT  L+N++  +K+K L  ++Q+ Q
Sbjct:  109 LVINLSSCRYESVRRAAQQYGFREGGEDDDWTLY--WTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKMFPKDFRFFPRTWCLPAD----WGDLQTYSRSRKNKTYICKPDSGCQGKGIFITRTVKEIKPGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNFSR---DAHSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLN--SACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEERQRGQ 456          

Query:  387 KTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQE-SNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKS-NEPSIVQEYIDKPCLL-DGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRG---VDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVS---FEILGFDILLDENLCPWLLEVNRSPSFGMDETL 1268
            + C + W +  +S           R+N F GM E+++K  LT   S MQKL P +Y ++P +W  P   ++    Y K       + +FI+KP  GA G GI L +  + I++ ++  +VQEY+  P L+ D  K DFR+Y +I   +PL  ++ REG+ R  TEKY         +++ HLTNYS+NK N  Y       D++ GSK+ LS++ ++ +++  + T  LW  I  I+VKT + + P ++ +Y      +   +DS     F+I+GFD+++ E+  P LLEVN +PS   D  +
Sbjct:   59 QPCDVYWHNVVLSDMNKIVTSPQSRVNKFPGMTELAKKISLTHSISSMQKLFPDEYAFYPNSWFLPAHLADFHAFYRKAQALGKTEMWFIVKPDEGAQGTGIYLINSPNQIRNVDQRQLVQEYVADPLLMNDKLKFDFRVYGVIKSINPLSIYVAREGMARFCTEKYEKPDSSNFKNLYAHLTNYSLNKANEAYVHSNTLQDQTRGSKRLLSTVFHQLESR-GVKTKRLWHDIKLILVKTTLAMLPEIMLHY------EHHFYDSTGPQCFQIMGFDVMIREDGTPILLEVNAAPSLTADHIV 354          

Query:  387 KTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQE-SNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKS-NEPSIVQEYIDKPCLL-DGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRG---VDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVS---FEILGFDILLDENLCPWLLEVNRSPSFGMDETL 1268
            + C + W +  +S           R+N F GM E+++K  LT   S MQKL P +Y ++P +W  P   ++    Y K       + +FI+KP  GA G GI L +  + I++ ++  +VQEY+  P L+ D  K DFR+Y +I   +PL  ++ REG+ R  TEKY         +++ HLTNYS+NK N  Y       D++ GSK+ LS++ ++ +++  + T  LW  I  I+VKT + + P ++ +Y      +   +DS     F+I+GFD+++ E+  P LLEVN +PS   D  +
Sbjct:  159 QPCDVYWHNVVLSDMNKIVTSPQSRVNKFPGMTELAKKISLTHSISSMQKLFPDEYAFYPNSWFLPAHLADFHAFYRKAQALGKTEMWFIVKPDEGAQGTGIYLINSPNQIRNVDQRQLVQEYVADPLLMNDKLKFDFRVYGVIKSINPLSIYVAREGMARFCTEKYEKPDSSNFKNLYAHLTNYSLNKANEAYVHSNTLQDQTRGSKRLLSTVFHQLESR-GVKTKRLWHDIKLILVKTTLAMLPEIMLHY------EHHFYDSTGPQCFQIMGFDVMIREDGTPILLEVNAAPSLTADHIV 454          

Query:  399 LIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXX--------XXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDA--LWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNI 1322
            +IW  + +   R+ EL  +QR+N F    E+++KD L +   + + +  + +++ P+ ++ P+E+  +        K                +KP N   G GI   +    I +  P +V  Y+  P L++ +K D RIYV +T   PL A++Y EGL RL++  Y  ++     + + HLTNYS+NK ++++ R    SS       +L    +   N   DA  L  +I D++VK+L+ +Q  +    R         F   +FE+ GFD+L+D+ L PWLLEVN SPS   D  LD  +K  L+ D   L  +
Sbjct:  103 VIWMGAPVKSVRMRELMPWQRLNQFPRSTELTKKDRLYENIERSKSIFGESFDFIPEFYVTPRENRKMENAFVRVAKEIAAAGGELCFPGEFIVKPTNSRQGKGIFFANSMADIPAEGPLLVSRYLKDPYLVNNHKFDLRIYVAVTSFYPLVAYVYSEGLARLASRPYDTSASSADSNEYVHLTNYSINKNSTSFVRNESMSSEDLGHKWTLGALLRYVENEGKDAKLLMLRIEDLIVKSLLSIQNSVATASRTN-----LRFACTNFELFGFDVLVDQALKPWLLEVNLSPSLACDAPLDSLLKTRLIADLLNLACV 415          

Query:  399 LIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXX--------XXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDA--LWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNI 1322
            +IW  + +   R+ EL  +QR+N F    E+++KD L +   + + +  + +++ P+ ++ P+E+  +        K                +KP N   G GI   +    I +  P +V  Y+  P L++ +K D RIYV +T   PL A++Y EGL RL++  Y  ++     + + HLTNYS+NK ++++ R    SS       +L    +   N   DA  L  +I D++VK+L+ +Q  +    R      L+ F   +FE+ GFD+L+D+ L PWLLEVN SPS   D  LD  +K  L+ D   L  +
Sbjct:  156 VIWMGAPVKSVRMRELMPWQRLNQFPRSTELTKKDRLYENIERSKSIFGESFDFIPEFYVTPRENRKMENAFVRVAKEIAAAGGELCFPGEFIVKPTNSRQGKGIFFANSMADIPAEGPLLVSRYLKDPYLVNNHKFDLRIYVAVTSFYPLVAYVYSEGLARLASRPYDTSASSADSNEYVHLTNYSINKNSTSFVRNESMSSEDLGHKWTLGALLRYVENEGKDAKLLMLRIEDLIVKSLLSIQNSVATASRT----NLR-FACTNFELFGFDVLVDQALKPWLLEVNLSPSLACDAPLDSLLKTRLIADLLNLACV 468          

Query:  456 QRINHFMGMVEISRKDFLTKKFSKMQKLRPK-------DYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLF----------SEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINT-DALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIK 1325
            Q I HF    E++RKDFL K + K +K + K       ++N+ P +++ P E +L    ++E +K      +I+KP  GA G GI LF           +D       P +VQ Y+  P L+ G K D RIYVL+T   PL A+++REG  R S  +Y+  S   +D  F HLTN +V K  ++Y    D   G K SL  L   FK+    +        + ++++++L  VQ  +I              D+  FE+ G+DIL DENL PWLLEVN SPS       D ++K  +L     +L+I+
Sbjct:   79 QMICHFRNDFELTRKDFLIKNYKKARKAKEKSGIDVVSEFNFLPSSYVLPTEYHLF---VEEFRKYPNDTIWIMKPVAGAQGKGIFLFRKLKHVQEWKKKDSSGSEALPYVVQCYVHNPYLVGGKKFDVRIYVLVTSFRPLNAWVHREGFARFSHSRYSTDS---VDDAFVHLTNVAVAKTAADY----DPERGLKWSLPKLFRFFKSVHGQSKLSKTMNDLTNVIIESLKSVQNLIIQ-------------DNHCFELYGYDILFDENLKPWLLEVNASPSLTASSQEDFELKYRILNHMIDVLDIE 363          

Query:  300 TANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIE-PHLDNETLKKRKDIEKRKQDLIDLLVRVQAS-----SSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDS 1613
            T  V+ +R+ ++ KI +++G+ L  +   K   ++W+DSF   E    +K +Q+INHF GM+EI RKD L++  ++M K+ P+DY  FPKTW+ P +                K+ FILKP +GA G GI L ++   I  +E  I Q YI +P L+DGYK D R+Y LIT  DPLR F+Y EGL R +T KY   +    + ++ HLTNYSVNK+NS+Y    D      +   S +N +  + N + +  W  + D+++KT++   P L HNY  C  G   +     FEILGFDIL+D  L P++LEVN SPSF  +E +DR+VK  L+ DT  L++   ++K++ L   +++ ++RL        ++ P L   T K + D +K   D   + V  +A      + +  +E  H+GNF ++ PP D +  DYY      S
Sbjct:  147 TICVSNSRYAMIGKISKTLGYKLVKES--KMWNILWSDSFPGVELFKNMKRFQQINHFPGMIEICRKDLLSRNLNRMLKIFPQDYKIFPKTWMLPADYG-----DAMNYALNHKRTFILKPDSGAQGRGIWLTNDLKTIGPHERLICQTYIHRPLLIDGYKFDLRVYTLITSVDPLRIFVYNEGLARFATNKYVEPTPGNANDLYMHLTNYSVNKRNSHYEL-CDNDDCGSKRKLSAINNWMRRHNYDVEEFWSNVDDVIIKTVLSAWPVLKHNYHACFPG--HDKIQACFEILGFDILVDWKLKPYILEVNHSPSFHTNEQVDREVKRPLIRDTLNLVSTVLADKRQILKEDRKRVKQRLLKIRGDPPVQRPRLGGGTSKPKIDAQKGSPDAQPVDVEPEAEDHGPLAQQIAWEESHLGNFRKIMPPPDLSKLDYYTRFYAQS 580          

Query:  294 QMTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMC--RTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAEL 1601
            +++  V  TRF++V K+  ++GF    +   +   + W+DS    + +  +K +Q+INHF GMVEI RKD L++  ++M K+ P DY  FPKTWL P ++   Y       K  +        A    G GI + ++   +   E  I Q YI++P L+DGYK D R+Y L+T  DPLR F+Y EGL R +T+KY   +     ++F HLTNY +N++NS Y  G +      +   S  N++    N +    W  + D ++KTL+   P L HNY +C  +  ++Q     SF++LGFDIL+D  L P++LEVN +PS   DE++D +VK  L+ DT  +L+    +K++ +   + + + RL    +  K    +   +      I +     +     + A + +  +E  H+GN+ R+ PP D +  +YY + 
Sbjct:  130 RLSVCVEHTRFQLVAKVTRNMGFQHVPEH--RLWNIQWSDSTPHHDLLRNMKRFQQINHFPGMVEICRKDLLSRNLNRMLKMFPGDYRIFPKTWLMPTDA---YDVAIYANKHKRTFILKPYSA--GQGRGIWITTDLRTVGKREKLICQTYIERPLLIDGYKFDLRVYTLVTSVDPLRIFVYNEGLARFATQKYVPPTTGNSHNVFMHLTNYCLNRRNSQYMVG-NGPEAGSKRKLSAFNKWLVDHNYDVGEFWASVDDAIIKTLISAWPTLKHNYNVCFPKHDKIQ----ASFQLLGFDILVDWKLKPYILEVNHTPSLSADESVDMEVKRPLIRDTLNMLSTALVDKEQIIRDDRTEHRARLLRNIYNKKAAAQMPGYS----SPIREVGGHDVRQACSIGALTQQIAWEESHLGNYRRIMPPRDSSKVNYYCKF 551          

Query:  399 LIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRP-KDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTR---GVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKP-SNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDD 1571
            L+WT   +  + +  L  YQR+NHF    E++RKD L K   +MQ LR  K ++  P+T++ P ES  L     + + P   K      A  + G GI + +  D I  +E ++V +YI  P  +DG+K D R+YVL+T  DPL  ++Y EG+VRL+T KY   +D   +    HL NYS+NK +S+Y R     DE  G K +LS+L+   K + + +T  L   I D+++K ++     +I   RM     + N ++  FE+ GFDIL+D  L PWLLE+N SPS G+D  LD KVK  L+ D    + I   S + KS Y   QK  R  + +  R    P    +T K +K       +L     R+  ++  +Y      G F+R+FP DD
Sbjct:  249 LLWTGVHMKLDIVRNLAPYQRVNHFPRSYEMTRKDRLYKNIERMQHLRGMKHFDIVPQTFVLPIESRDLVVAHNKHRGPWIVKP-----AASSRGRGIFIVNSPDQIPQDEQAVVSKYIVDPLCIDGHKCDLRVYVLVTSFDPLIIYLYEEGIVRLATVKYDRHADNLWNPCM-HLCNYSINKYHSDYIRSSDAQDEDVGHKWTLSALLRHLKLQ-SCDTRQLMLNIEDLIIKAVLACAQSIISACRMF----VPNGNNC-FELYGFDILIDNALKPWLLEINLSPSMGVDSPLDTKVKSCLMADLLTCVGIPAYSPEMKSHY--DQKWSRFRSSSCQRIATFPSTSQKTKKSKKKGAAINLNLTGEEQRILRNARLQYSRR---GGFVRIFPTDD 627          

Query:  399 LIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRP-KDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTR---GVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKP-SNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDD 1571
            L+WT   +  + +  L  YQR+NHF    E++RKD L K   +MQ LR  K ++  P+T++ P ES  L     + + P   K      A  + G GI + +  D I  +E ++V +YI  P  +DG+K D R+YVL+T  DPL  ++Y EG+VRL+T KY   +D   +    HL NYS+NK +S+Y R     DE  G K +LS+L+   K + + +T  L   I D+++K ++     +I   RM     + N ++  FE+ GFDIL+D  L PWLLE+N SPS G+D  LD KVK  L+ D    + I   S + KS Y   QK  R  + +  R    P    +T K +K       +L     R+  ++  +Y      G F+R+FP DD
Sbjct:  249 LLWTGVHMKLDIVRNLAPYQRVNHFPRSYEMTRKDRLYKNIERMQHLRGMKHFDIVPQTFVLPIESRDLVVAHNKHRGPWIVKP-----AASSRGRGIFIVNSPDQIPQDEQAVVSKYIVDPLCIDGHKCDLRVYVLVTSFDPLIIYLYEEGIVRLATVKYDRHADNLWNPCM-HLCNYSINKYHSDYIRSSDAQDEDVGHKWTLSALLRHLKLQ-SCDTRQLMLNIEDLIIKAVLACAQSIISACRMF----VPNGNNC-FELYGFDILIDNALKPWLLEINLSPSMGVDSPLDTKVKSCLMADLLTCVGIPAYSPEMKSHY--DQKWSRFRSSSCQRIATFPSTSQKTKKSKKKGAAINLNLTGEEQRILRNARLQYSRR---GGFVRIFPTDD 627          

Query:  444 LKSYQRINHFMGMVEISRKDFLTKKFSK-MQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVD------EXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLL--VDTFRLLNIKPS---NKQKSL 1349
            ++SYQ+INH  G   I RKD   K   + M K   K++ + P+T++ P +   L ++  +  +   K       +  A G GIR+ +    I    P IVQ+YI++P L++G K D R+YVL+T  +PLR F+Y  GL R ++ KY+  +D   D    HLTNYS+NK +SNY++  D           K   + L NR      + TD LW+ +  +V++T +L   + I++  M R      +    FE+ GFD++LD +L PWLLEVN SPS   +  LD  VK  L+  V    L N+ P    +KQK L
Sbjct:  370 IRSYQKINHLPGSFRIGRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPNDLGALRRHWPKYAQRNTKWIIKPPAS--ARGAGIRVINRWGQIPKRRPLIVQKYIERPLLINGSKFDLRLYVLVTSVNPLRVFMYHNGLARFASVKYSAKTDTLNDRCM-HLTNYSINKFSSNYSKNEDVNACHGHKWTIKSLWTYLANR-----GVRTDCLWEALRSLVLRT-ILAGENGINS--MIRANVESKYS--CFELFGFDVILDSDLVPWLLEVNISPSLHSELPLDAHVKAPLVQGVLNTALYNVPPKLSLDKQKEL 670          

Query:  297 MTANVNGTRFEIVKKILESVGF-TLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNIN---TDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLF 1625
            +TANV GT++EIV+ ++E + F   RDD+  +T  LIW DS +  E+I EL++YQRINHF GM EI RKD L +  +KM K +P++Y++ PKTW+FP E      Y+KE K+  K+K FI+KPANGAMG GI L    + +   +  IVQEY+DKP L++GYK D R Y+L+T CDPLR F+Y +GLVR+ TEKY   ++  ++ ++ HLTNYSVNK N N+ R  DE+       S  +  F     IN       W  + ++VVKTL++ +PH++H YRMCR GQ     SV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK   L++  +LLNI+ S+K+++L  QK +AQRRL       K+     +E  K+R  +E+R+++L + L +V+   SR+  E RH+GN+ R++PPDDK + + Y  LL  +F  F
Sbjct:   43 ITANVIGTKYEIVRIVIEELTFHKARDDD--ETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMAKMIKSQPQEYSFIPKTWIFPAECTQFQNYVKELKRKGKQKTFIVKPANGAMGHGISLIRNCEKLPVQDHFIVQEYLDKPFLMEGYKFDLRFYILVTSCDPLRVFLYNDGLVRMGTEKYHTPNESNLNQLYMHLTNYSVNKHNENFER--DETVDKGSKRS--IGWFTEFLRINDYDVAKFWGDVSELVVKTLLVAEPHVLHAYRMCRPGQPPGSASVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDYDVKKGALLNALKLLNIRASDKRRNLAQQKAEAQRRLYGQGSMRKLTAG-SSEWEKQRHLLERRREELKERLAQVRKQVSRDEHEKRHLGNYRRIYPPDDKLLLEKYESLLSAAFQTF 482          

Query:  297 MTANVNGTRFEIVKKILESVGF-TLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNIN---TDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIP 1817
            +TANV GT++EIV+ ++E + F   RDD+  +T  LIW DS +  E+I EL++YQRINHF GM EI RKD L +  +KM K +P++Y++ PKTW+FP E      Y+KE K+  K+K FI+KPANGAMG GI L    + +   +  IVQEY+DKP L++GYK D R Y+L+T CDPLR F+Y +GLVR+ TEKY   ++  ++ ++ HLTNYSVNK N N+ R  DE+       S  +  F     IN       W  + ++VVKTL++ +PH++H YRMCR GQ     SV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK   L++  +LLNI+ S+K+++L  QK +AQRRL       K+     +E  K+R  +E+R+++L + L +V+   SR+  E RH+GN+ R++PPDDK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L+ K    +  ++ + +P
Sbjct:   43 ITANVIGTKYEIVRIVIEELTFHKARDDD--ETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMAKMIKSQPQEYSFIPKTWIFPAECTQFQNYVKELKRKGKQKTFIVKPANGAMGHGISLIRNCEKLPVQDHFIVQEYLDKPFLMEGYKFDLRFYILVTSCDPLRVFLYNDGLVRMGTEKYHTPNESNLNQLYMHLTNYSVNKHNENFER--DETVDKGSKRS--IGWFTEFLRINDYDVAKFWGDVSELVVKTLLVAEPHVLHAYRMCRPGQPPGSASVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDYDVKKGALLNALKLLNIRASDKRRNLAQQKAEAQRRLYGQGSMRKLTAG-SSEWEKQRHLLERRREELKERLAQVRKQVSRDEHEKRHLGNYRRIYPPDDKLLLEKYESLLSAAFQTF------------LAGRAASLQKEMNNPLKRMKEEDILDLLEQCELDDEKLMGKTSKQKGPKVLSSMP 537          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCF--SHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQF 2783
            IRYPG+++ E ++ML +I +NW++ +  VA+YWL  L+A K+ K++ IVR N+  ++   +    D+ + R+ RL ++V+NRLLW+ G GL  C   S   SW+ +F+ + +++   EL  C RVVQLC DC+LIVY+F
Sbjct:  723 IRYPGKSEEEAEAMLDEILNNWKYHKPKVASYWLVKLDATKQRKVLDIVRTNIRSVLQRIWS-EPDVESLRLYRLFNRVFNRLLWSHGQGLWNCLSTSGRSSWECVFNKTSEVVNAQELRCCQRVVQLCRDCLLIVYKF 860          

Query:  297 MTANVNGTRFEIVKKILESVGF-TLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNIN---TDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIP 1817
            +TANV GT++EIV+ ++E + F   RDD+  +T  LIW DS +  E+I EL++YQRINHF GM EI RKD L +  +KM K +P++Y++ PKTW+FP E      Y+KE K+  K+K FI+KPANGAMG GI L    + +   +  IVQEY+DKP L++GYK D R Y+L+T CDPLR F+Y +GLVR+ TEKY   ++  ++ ++ HLTNYSVNK N N+ R  DE+       S  +  F     IN       W  + ++VVKTL++ +PH++H YRMCR GQ     SV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK   L++  +LLNI+ S+K+++L  QK +AQRRL       K+     +E  K+R  +E+R+++L + L +V+   SR+  E RH+GN+ R++PPDDK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L+ K    +  ++ + +P
Sbjct:   43 ITANVIGTKYEIVRIVIEELTFHKARDDD--ETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMAKMIKSQPQEYSFIPKTWIFPAECTQFQNYVKELKRKGKQKTFIVKPANGAMGHGISLIRNCEKLPVQDHFIVQEYLDKPFLMEGYKFDLRFYILVTSCDPLRVFLYNDGLVRMGTEKYHTPNESNLNQLYMHLTNYSVNKHNENFER--DETVDKGSKRS--IGWFTEFLRINDYDVAKFWGDVSELVVKTLLVAEPHVLHAYRMCRPGQPPGSASVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDYDVKKGALLNALKLLNIRASDKRRNLAQQKAEAQRRLYGQGSMRKLTAG-SSEWEKQRHLLERRREELKERLAQVRKQVSRDEHEKRHLGNYRRIYPPDDKLLLEKYESLLSAAFQTF------------LAGRAASLQKEMNNPLKRMKEEDILDLLEQCELDDEKLMGKTSKQKGPKVLSSMP 537          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFS-HFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQF 2783
            IRYPG+++ E ++ML +I +NW++ +  VA+YWL  L+A K+ K++ IVR N+  ++   +    D+ + R+ RL ++V+NRLLW+ G GL  C S    SW+ +F+ + +++   EL  C RVVQLC DC+LIVY+F
Sbjct:  723 IRYPGKSEEEAEAMLDEILNNWKYHKPKVASYWLVKLDATKQRKVLDIVRTNIRSVLQRIWS-EPDVESLRLYRLFNRVFNRLLWSHGQGLWNCLSTSGSSWECVFNKTSEVVNAQELRCCQRVVQLCRDCLLIVYKF 859          

Query:  306 NVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTK---FNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREY--FENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREE 1718
            N+   ++E V++     G  +R+    +   L WTD  +S +R+ ++K YQ+INHF GM EI RKD L +  ++M KL PK+YN FP+TW  P +    Y   +   +  K K FI KP +G  G GI L   +  I+  E  I Q Y+ KP ++DG+K D RIYVL+T CDP R F+Y EGLVR  T  Y   +   ++ +  HLTNY++NK + N+ R  D  S  K      ++ FK      + +T+ LW  I D+++KTL+   P L HNY+ C         S  FEILGFD+LLD  L PWLLEVN SPSF  D  LDR+VK SLL DT  L+N+   +++K    +K++ + R                  L++ +  E R ++    L + QA+S  +   +E +H+G F R+FP D    Y+ Y +    S +LF +      S    +  +Q LQ     Q ++E
Sbjct:   57 NLTNCKYESVRRAARRYG--IREAAEGEDWTLYWTDCSVSLDRVMDMKRYQKINHFPGMNEICRKDLLARNMNRMLKLFPKEYNIFPRTWCLPAD----YSDFQAYTRAKKHKTFICKPDSGCQGRGIYLTKSNKDIRPGEHMICQVYMSKPFIIDGFKFDLRIYVLVTSCDPFRVFMYDEGLVRFCTTHYTEPTVSNLEDVCMHLTNYAINKHSENFVRDEDTGSKRK------LSSFKKHMEDMSYDTEKLWTDIEDVIIKTLISAHPILKHNYQTCFPNHASG--SACFEILGFDVLLDRRLKPWLLEVNHSPSFTTDSRLDREVKDSLLYDTLVLINLGACDRRKITEEEKRRVKER------------------LQQNRSREARNEE----LRQSQAASMEQMQKYEAKHMGGFRRIFPRDGGEKYEKYFQ---HSSSLFQET---AASKAREECARQQLQELRLKQEQKE 490          

Query:  306 NVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTK---FNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREY--FENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREE 1718
            N+   ++E V++     G  +R+    +   L WTD  +S +R+ ++K YQ+INHF GM EI RKD L +  ++M KL PK+YN FP+TW  P +    Y   +   +  K K FI KP +G  G GI L   +  I+  E  I Q Y+ KP ++DG+K D RIYVL+T CDP R F+Y EGLVR  T  Y   +   ++ +  HLTNY++NK + N+ R  D  S  K      ++ FK      + +T+ LW  I D+++KTL+   P L HNY+ C         S  FEILGFD+LLD  L PWLLEVN SPSF  D  LDR+VK SLL DT  L+N+   +++K    +K++ + R                  L++ +  E R ++    L + QA+S  +   +E +H+G F R+FP D    Y+ Y +    S +LF +      S    +  +Q LQ     Q ++E
Sbjct:   57 NLTNCKYESVRRAARRYG--IREAAEGEDWTLYWTDCSVSLDRVMDMKRYQKINHFPGMNEICRKDLLARNMNRMLKLFPKEYNIFPRTWCLPAD----YSDFQAYTRAKKHKTFICKPDSGCQGRGIYLTKSNKDIRPGEHMICQVYMSKPFIIDGFKFDLRIYVLVTSCDPFRVFMYDEGLVRFCTTHYTEPTVSNLEDVCMHLTNYAINKHSENFVRDEDTGSKRK------LSSFKKHMEDMSYDTEKLWTDIEDVIIKTLISAHPILKHNYQTCFPNHASG--SACFEILGFDVLLDRRLKPWLLEVNHSPSFTTDSRLDREVKDSLLYDTLVLINLGACDRRKITEEEKRRVKER------------------LQQNRSREARNEE----LRQSQAASMEQMQKYEAKHMGGFRRIFPRDGGEKYEKYFQ---HSSSLFQET---AASKAREECARQQLQELRLKQEQKE 490          

Query:  297 MTANVNGTRFEIVKKILESVGFT-LRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIP 1817
            +T N   T  EIV+ + E + FT  RDD+  +T  LIW D  +  E+I EL++YQRINHF GM EI RKD L +  +KM K +P +YN+ P+TW+FP E      YIKE KK  ++K FI+KPANGAMG GI L    + +++ +  IVQEY++KP LL+ YK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   S+  +  ++ HLTNYSVNK N N+ R   E+ GSK+S+      F    + +    W  I D+VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+K+L  QK +AQ+RL       ++ P   ++  K+R  +E+RK++L + L +V+   SRE +ENRH+GN+ R++PP+DK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L  K   P+     + +P
Sbjct:   42 ITENWVSTTGEIVRLVTEEMMFTKARDDD--ETANLIWNDCAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMTKMIKCQPHEYNFIPRTWIFPAEYTQFQTYIKELKKKRRQKTFIIKPANGAMGHGISLTRNGEKLQAQDHLIVQEYLEKPFLLESYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHPPSESNLSQLYMHLTNYSVNKHNENFERDETENRGSKRSIK-WFTEFLRANDYDISKFWNDISDLVVKTLIVAEPHVLHAYRMCRPGQHPTSESVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDHDVKKGVLLNALKLLNIRASDKKKNLAKQKAEAQKRLYGQGSMKRLSP-ASSDWEKQRHTLERRKEELKERLAQVRKQISREEYENRHLGNYRRIYPPEDKLLLEKYEGLLATAFQTF------------LAGRAASLQREMNNPLKRMKEEDILDLLEQCELDDEKLSGKPTRPKEPRTLSSMP 536          

Query:  297 MTANVNGTRFEIVKKILESVGFT-LRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIP 1817
            +T N   T  EIV+ + E + FT  RDD+  +T  LIW D  +  E+I EL++YQRINHF GM EI RKD L +  +KM K +P +YN+ P+TW+FP E      YIKE KK  ++K FI+KPANGAMG GI L    + +++ +  IVQEY++KP LL+ YK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   S+  +  ++ HLTNYSVNK N N+ R   E+ GSK+S+      F    + +    W  I D+VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+K+L  QK +AQ+RL       ++ P   ++  K+R  +E+RK++L + L +V+   SRE +ENRH+GN+ R++PP+DK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L  K   P+     + +P
Sbjct:   42 ITENWVSTTGEIVRLVTEEMMFTKARDDD--ETANLIWNDCAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMTKMIKCQPHEYNFIPRTWIFPAEYTQFQTYIKELKKKRRQKTFIIKPANGAMGHGISLTRNGEKLQAQDHLIVQEYLEKPFLLESYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHPPSESNLSQLYMHLTNYSVNKHNENFERDETENRGSKRSIK-WFTEFLRANDYDISKFWNDISDLVVKTLIVAEPHVLHAYRMCRPGQHPTSESVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDHDVKKGVLLNALKLLNIRASDKKKNLAKQKAEAQKRLYGQGSMKRLSP-ASSDWEKQRHTLERRKEELKERLAQVRKQISREEYENRHLGNYRRIYPPEDKLLLEKYEGLLATAFQTF------------LAGRAASLQREMNNPLKRMKEEDILDLLEQCELDDEKLSGKPTRPKEPRTLSSMP 536          

Query: 2373 IRYPGQTDVE-TKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSH-FKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFS 2786
            IR PG+   E T S + +I  NW + +  VA+YWL  L++ K+ K++ IVR N+  ++   +K S D+    + R  ++V+NRLLWN G GL  CFS+   SW+ IF  S +++ P +   C R+VQLC DC+L VY+++
Sbjct:  715 IRIPGKGVEEITHSHIDEIMDNWTYHKSKVASYWLIKLDSVKQRKVLDIVRTNIRSVLQRIWKVS-DVECLHIYRSFNRVFNRLLWNHGQGLWSCFSNSGTSWETIFCKSTEVVTPQQFQCCQRLVQLCKDCLLAVYKYA 853          

Query:  300 TANVNGTRFEIVKKILESVGFT-LRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIP 1817
            + NV+ T+  I++ + E + FT  RDD+  +T  LIW D  +  E+I EL++YQRINHF GM EI RKD L +  +KM K +P +YN+ P+TW+FP E      YIKE KK  ++K FI+KPANGAMG GI L    + +++ +  IVQEY++KP LL+ YK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   S+  +  ++ HLTNYSVNK N N+ R   E+ GSK+S+      F    + +    W  I D+VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+K+L  QK +AQ+RL       ++ P   ++  K+R  +E+RK++L + L +V+   SRE +ENRH+GN+ R++PP+DK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L  K   P+     + +P
Sbjct:    1 SQNVSITQDFIIRLVTEEMMFTKARDDD--ETANLIWNDCAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMTKMIKCQPHEYNFIPRTWIFPAEYTQFQTYIKELKKKRRQKTFIIKPANGAMGHGISLTRNGEKLQAQDHLIVQEYLEKPFLLESYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHPPSESNLSQLYMHLTNYSVNKHNENFERDETENRGSKRSIK-WFTEFLRANDYDISKFWNDISDLVVKTLIVAEPHVLHAYRMCRPGQHPTSESVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDHDVKKGVLLNALKLLNIRASDKKKNLAKQKAEAQKRLYGQGSMKRLSP-ASSDWEKQRHTLERRKEELKERLAQVRKQISREEYENRHLGNYRRIYPPEDKLLLEKYEGLLATAFQTF------------LAGRAASLQREMNNPLKRMKEEDILDLLEQCELDDEKLSGKPTRPKEPRTLSSMP 494          

Query: 2373 IRYPGQTDVE-TKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSH-FKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSI-SLSQSSTPRSDKSFASQSVI 2849
            IR PG+   E T S + +I  NW + +  VA+YWL  L++ K+ K++ IVR N+  ++   +K S D+    + R  ++V+NRLLWN G GL  CFS+   SW+ IF  S +++ P +   C R+VQLC DC+L VY+++  S     +P  D S  S ++I
Sbjct:  670 IRIPGKGVEEITHSHIDEIMDNWTYHKSKVASYWLIKLDSVKQRKVLDIVRTNIRSVLQRIWKVS-DVECLHIYRSFNRVFNRLLWNHGQGLWSCFSNSGTSWETIFCKSTEVVTPQQFQCCQRLVQLCKDCLLAVYKYATDSRVAGMSPDWDDSRYSLTLI 830          

Query:  333 VKKILESVGFT-LRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIP 1817
            V+ + E + FT  RDD+  +T  LIW D  +  E+I EL++YQRINHF GM EI RKD L +  +KM K +P +YN+ P+TW+FP E      YIKE KK  ++K FI+KPANGAMG GI L    + +++ +  IVQEY++KP LL+ YK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   S+  +  ++ HLTNYSVNK N N+ R   E+ GSK+S+      F    + +    W  I D+VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+K+L  QK +AQ+RL       ++ P   ++  K+R  +E+RK++L + L +V+   SRE +ENRH+GN+ R++PP+DK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L  K   P+     + +P
Sbjct:    5 VRLVTEEMMFTKARDDD--ETANLIWNDCAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMTKMIKCQPHEYNFIPRTWIFPAEYTQFQTYIKELKKKRRQKTFIIKPANGAMGHGISLTRNGEKLQAQDHLIVQEYLEKPFLLESYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHPPSESNLSQLYMHLTNYSVNKHNENFERDETENRGSKRSIK-WFTEFLRANDYDISKFWNDISDLVVKTLIVAEPHVLHAYRMCRPGQHPTSESVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDHDVKKGVLLNALKLLNIRASDKKKNLAKQKAEAQKRLYGQGSMKRLSP-ASSDWEKQRHTLERRKEELKERLAQVRKQISREEYENRHLGNYRRIYPPEDKLLLEKYEGLLATAFQTF------------LAGRAASLQREMNNPLKRMKEEDILDLLEQCELDDEKLSGKPTRPKEPRTLSSMP 487          

Query: 2373 IRYPGQTDVE-TKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSH-FKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSI-SLSQSSTPRSDKSFASQSVI 2849
            IR PG+   E T S + +I  NW + +  VA+YWL  L++ K+ K++ IVR N+  ++   +K S D+    + R  ++V+NRLLWN G GL  CFS+   SW+ IF  S +++ P +   C R+VQLC DC+L VY+++  S     +P  D S  S ++I
Sbjct:  640 IRIPGKGVEEITHSHIDEIMDNWTYHKSKVASYWLIKLDSVKQRKVLDIVRTNIRSVLQRIWKVS-DVECLHIYRSFNRVFNRLLWNHGQGLWSCFSNSGTSWETIFCKSTEVVTPQQFQCCQRLVQLCKDCLLAVYKYATDSRVAGMSPDWDDSRYSLTLI 800          

Query:  333 VKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQAS--SSREYFENRHVGNFLRVFPPDDKTVYDYY 1592
            V++     G     DE   T Y  WTD  +S ER+ ++K +Q+INHF GM EI RKD L +  +++ KL PK+YN FP+TW  P +    Y  ++   +  K   +I KP +G  G GI L      IK  +  I Q+YI KP L+DG+K D RIY L+T C+PLR F+Y+EGL R +T  Y   S   +D +  HLTNY++NK N N+ R   +     +   S +N +    + +T  LW+ I D+++KTL+   P L HNYR C    +    S  FEILGFDILLD  L PWL+EVN SPSF  D  LDR+VK  L+ DT  LLN++  +K+K +   K++ + RL         + ++  ET        +R+Q     L   QAS  +  E +E+ H+G + R++P D+  VY+ +
Sbjct:   24 VRRAARRCGLKEVGDEEEWTVY--WTDCSVSLERVMDMKRFQKINHFPGMNEICRKDLLARNMNRLSKLFPKEYNIFPRTWCLPAD----YGDLQAHCRTKKNSTYICKPDSGCQGRGIFLSKNLKDIKHGDNMICQQYIPKPFLVDGFKFDLRIYALVTSCEPLRIFVYKEGLARFATMNYVEPSHSNLDDVCMHLTNYAINKHNENFIR---DDLTGSKRKLSTLNTWLENNHYDTCRLWEDIDDVIIKTLISAHPILKHNYRTCFPNYVAG--SACFEILGFDILLDRKLKPWLIEVNHSPSFTTDSILDREVKDPLIQDTLNLLNLRACDKRKVIEEDKRRVKERL--------FQRNVPRET--------RREQ-----LETSQASRLAQMEKYEDSHLGGYRRIYPRDNGEVYEKF 413          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWK----------LPQNAELT 1805
            +TANV GT+FEIV+ +++ +GF    DE  +T  LIW D+ + QE+IT+L++YQRINHF GM EI RKDFL +  +KM K RP DY + P+TW+FP E      Y+KE KK  K+K FI+KPANGAMG GI L    D + S +  IVQEYI+KP L++GYK D RIY+L+T CDPL+ F+Y +GLVR+ TEKY   ++  +  ++ HLTNYSVNK N  + R   E  GSK+S+      F      +    W  I ++VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDILLD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+K+L  QK +AQRRL       ++ P   ++  ++R  +E+RK++L + L++V+   S+E  ENRH+GN+ R++PP+DK + + Y  LL  +F  F        S  +    ++M       + REED+++ ++QCE ++  L+ K            +P+ AE+T
Sbjct:   41 ITANVAGTKFEIVRLVIDEMGFMKTPDED-ETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPMDYTFVPRTWIFPSEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKVPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNERFERNETEDKGSKRSIK-WFTEFLQANQHDVTKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNPVRRLSPG-SSDWEQQRHQLERRKEELKERLLQVRKQVSQEEHENRHMGNYRRIYPPEDKALLEKYEGLLAVAFQTF-------LSGRAASFQREMNNPL--KKMREEDLLDLLEQCEIDDEKLMGKTGRVRGPKPLCCMPECAEVT 541          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFS-HFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFS 2786
            IR+PG++D E++ ++  I  NW+H +  VA+YWL  L++ K+ K++ IV++++  ++   ++   D     + R+ ++V+NRLLW+ G GL  CF     SW+ IFS S +++ PL+L  C R+V+LC  C+L+VY+++
Sbjct:  693 IRFPGKSDAESELLIEDIMDNWKHYKTKVASYWLIKLDSVKQRKVLDIVKSSIRTVLPRIWRV-PDAEELSLYRIFNRVFNRLLWSHGQGLWSCFCDSGSSWESIFSKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYT 830          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWK----------LPQNAELT 1805
            +TANV GT+FEIV+ +++ +GF    DE  +T  LIW D+ + QE+IT+L++YQRINHF GM EI RKDFL +  +KM K RP DY + P+TW+FP E      Y+KE KK  K+K FI+KPANGAMG GI L    D + S +  IVQEYI+KP L++GYK D RIY+L+T CDPL+ F+Y +GLVR+ TEKY   ++  +  ++ HLTNYSVNK N  + R   E  GSK+S+      F      +    W  I ++VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDILLD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+K+L  QK +AQRRL       ++ P   ++  ++R  +E+RK++L + L++V+   S+E  ENRH+GN+ R++PP+DK + + Y  LL  +F  F        S  +    ++M       + REED+++ ++QCE ++  L+ K            +P+ AE+T
Sbjct:   41 ITANVAGTKFEIVRLVIDEMGFMKTPDED-ETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPMDYTFVPRTWIFPSEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKVPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNERFERNETEDKGSKRSIK-WFTEFLQANQHDVTKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNPVRRLSPG-SSDWEQQRHQLERRKEELKERLLQVRKQVSQEEHENRHMGNYRRIYPPEDKALLEKYEGLLAVAFQTF-------LSGRAASFQREMNNPL--KKMREEDLLDLLEQCEIDDEKLMGKTGRVRGPKPLCCMPECAEVT 541          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFS-HFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFS 2786
            IR+PG++D E++ ++  I  NW+H +  VA+YWL  L++ K+ K++ IV++++  ++   ++   D     + R+ ++V+NRLLW+ G GL  CF     SW+ IFS S +++ PL+L  C R+V+LC  C+L+VY+++
Sbjct:  698 IRFPGKSDAESELLIEDIMDNWKHYKTKVASYWLIKLDSVKQRKVLDIVKSSIRTVLPRIWRV-PDAEELSLYRIFNRVFNRLLWSHGQGLWSCFCDSGSSWESIFSKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYT 835          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWK----------LPQNAELT 1805
            +TANV GT+FEIV+ +++ +GF    DE  +T  LIW D+ + QE+IT+L++YQRINHF GM EI RKDFL +  +KM K RP DY + P+TW+FP E      Y+KE KK  K+K FI+KPANGAMG GI L    D + S +  IVQEYI+KP L++GYK D RIY+L+T CDPL+ F+Y +GLVR+ TEKY   ++  +  ++ HLTNYSVNK N  + R   E  GSK+S+      F      +    W  I ++VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDILLD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+K+L  QK +AQRRL       ++ P   ++  ++R  +E+RK++L + L++V+   S+E  ENRH+GN+ R++PP+DK + + Y  LL  +F  F        S  +    ++M       + REED+++ ++QCE ++  L+ K            +P+ AE+T
Sbjct:   41 ITANVAGTKFEIVRLVIDEMGFMKTPDED-ETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPMDYTFVPRTWIFPSEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKVPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNERFERNETEDKGSKRSIK-WFTEFLQANQHDVTKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNPVRRLSPG-SSDWEQQRHQLERRKEELKERLLQVRKQVSQEEHENRHMGNYRRIYPPEDKALLEKYEGLLAVAFQTF-------LSGRAASFQREMNNPL--KKMREEDLLDLLEQCEIDDEKLMGKTGRVRGPKPLCCMPECAEVT 541          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFS-HFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFS 2786
            IR+PG++D E++ ++  I  NW+H +  VA+YWL  L++ K+ K++ IV++++  ++   ++   D     + R+ ++V+NRLLW+ G GL  CF     SW+ IFS S +++ PL+L  C R+V+LC  C+L+VY+++
Sbjct:  718 IRFPGKSDAESELLIEDIMDNWKHYKTKVASYWLIKLDSVKQRKVLDIVKSSIRTVLPRIWRV-PDAEELSLYRIFNRVFNRLLWSHGQGLWSCFCDSGSSWESIFSKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYT 855          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQ 1373
            +  N++  R++ V++  +  G     D    T Y  WTD  +S ER+ E+KSYQ+INHF GM EI RKD L +  S+M KL PKD+++FP+TW  P +    +  ++   +  K K +I KP +G  G GI +      IK  E  I Q YI KP ++DG+K D R+YVL+T CDPLR F+Y EGL R +T  Y+  +   +D I  HLTNYS+NK +SN+   V ++    +   S  N +      + + +W+ I D+++KTL+   P + HNY  C      N  S  FEILGFDILLD  L PWLLEVN SPSF  D  LD++VK SLL D   L+N+   +K+K L  ++Q+ +
Sbjct:   60 LVINLSNCRYDSVRRAAQQYGLREAGDNDDWTLY--WTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKLFPKDFHFFPRTWCLPAD----WGDLQTYSRTRKNKTYICKPDSGCQGRGIFITRSVKEIKPGEDMICQLYISKPFIIDGFKFDLRVYVLVTSCDPLRVFVYNEGLARFATTSYSHPNLDNLDEICMHLTNYSINKHSSNF---VQDAFSGSKRKLSTFNSYMKTHGYDVEQIWRGIEDVIIKTLISAHPVIKHNYHTCFPSHTLN--SACFEILGFDILLDRKLKPWLLEVNHSPSFSTDSKLDKEVKDSLLYDALVLINLGNCDKKKVLEEERQRGR 407          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEEN 1760
            +  N+   ++E V++  +  G     ++   T Y  WTD  +S ER+ ++K +Q+INHF GM EI RKD L +  ++MQKL P +YN FP+TW  P +    Y   +   +  K + +I KP +G  G GI +      IK  E  I Q+YI KP L+DG+K D RIYVLIT CDPLR F+Y EGL R +T  Y   S   ++ +  HLTNY++NK N N+ R   + +   +   S +N +  + + +   LW  I DI++KT++     L HNYR C    L       FEILGFDILLD  L PWLLEVN SPSF  D  LDR+VK +LL D   L+N++  +K+K +   K++ + RL    F    +P    ET  +R+  E  +  + D          +E +E+ H+G + R++P  D    + YA     + +LF +      S    +  +Q L+     Q ++E+   + ++   E+N
Sbjct:   57 LAINLTNCKYESVRRAAQMCGLKEVGEDEEWTVY--WTDCSVSLERVMDMKRFQKINHFPGMTEICRKDLLARNLNRMQKLYPTEYNIFPRTWCLPAD----YGDFQAYGRQRKTRTYICKPDSGCQGRGIFITRTPKEIKPGEHMICQQYITKPFLIDGFKFDMRIYVLITSCDPLRIFMYEEGLARFATMPYVEPSHNNLEEVCMHLTNYAINKHNENFVR---DDAVGSKRKLSTLNAWLREHSHDPQELWGDIEDIIIKTIISAHSVLRHNYRTCFPQYLCGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTTDSRLDREVKDALLCDAMNLVNLRGCDKKKVIEEDKRRVKERL----FPCHQQP---RET--RREQFELSQAAMHD----------QERYEDSHLGGYRRIYPGPDS---EKYAPFFKHNGSLFQET---AASKAREECARQQLEEIRLKQEQQENPGTKKRKENKEQN 510          

Query:  297 MTANVNGTRFEIVKKILESVGFT-LRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIP 1817
            +TANV GT++EIV+ + E + FT  RDD+  +T  LIW D  +  E+I EL++YQRINHF GM EI RKD L +  +KM K +P +YN+ P+TW+FP E      YIKE KK  ++K FI+KPANGAMG GI L    + +++ +  IVQEY++KP LL+ YK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   S+  +  ++ HLTNYSVNK N N+ R   E+ GSK+S+      F    + +    W  I D+VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+K+L  QK +AQ+RL       ++ P   ++  K+R  +E+RK++L + L +V+   SRE +ENRH+GN+ R++PP+DK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L  K   P+     + +P
Sbjct:   43 ITANVVGTKYEIVRLVTEEMMFTKARDDD--ETANLIWNDCAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMTKMIKCQPHEYNFIPRTWIFPAEYTQFQTYIKELKKKRRQKTFIIKPANGAMGHGISLTRNGEKLQAQDHLIVQEYLEKPFLLESYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHPPSESNLSQLYMHLTNYSVNKHNENFERDETENRGSKRSIK-WFTEFLRANDYDISKFWNDISDLVVKTLIVAEPHVLHAYRMCRPGQHPTSESVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDHDVKKGVLLNALKLLNIRASDKKKNLAKQKAEAQKRLYGQGSMKRLSP-ASSDWEKQRHTLERRKEELKERLAQVRKQISREEYENRHLGNYRRIYPPEDKLLLEKYEGLLATAFQTF------------LAGRAASLQREMNNPLKRMKEEDILDLLEQCELDDEKLSGKPTRPKEPRTLSSMP 537          

Query: 2373 IRYPGQTDVE-TKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSH-FKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFS 2786
            IR PG+   E T S + +I  NW + +  VA+YWL  L++ K+ K++ IVR N+  ++   +K S D+    + R  ++V+NRLLWN G GL  CFS+   SW+ IF  S +++ P +   C R+VQLC DC+L VY+++
Sbjct:  716 IRIPGKGVEEITHSHIDEIMDNWTYHKSKVASYWLIKLDSVKQRKVLDIVRTNIRSVLQRIWKVS-DVECLHIYRSFNRVFNRLLWNHGQGLWSCFSNSGTSWETIFCKSTEVVTPQQFQCCQRLVQLCKDCLLAVYKYA 854          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEK 1775
            +TANV GT+FEIV+ +++ +GF    DE  +T  LIW DS + QE+I+EL++YQRINHF GM EI RKDFL +  +KM K RP DY + P+TW+FP E      Y+KE KK  K+K FI+KPANGAMG GI L    D + S +  IVQEYI+KP L++GYK D RIY+L+T CDPL+ F+Y +GLVR+ TEKY   ++  +  ++ HLTNYSVNK N ++ R   E+ GSK+S+      F      +    W  I ++VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDILLD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+++L  QK +AQRRL       ++ P   ++  ++R  +E+RK++L + L +V+   SRE  ENRH+GN+ R++PP+DK + + Y  LL  +F  F         +    + Q+ L + +  + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ITANVAGTKFEIVRLVIDEMGFMKTPDED-ETSNLIWCDSAVQQEKISELQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPLDYTFVPRTWIFPAEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKRSIK-WFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQKAEAQRRLYGQNSIKRLLPG-SSDWEQQRHQLERRKEELKERLAQVRKQISREEHENRHMGNYRRIYPPEDKALLEKYENLLAVAFQTF--------LSGRAASFQRELNNPL-KRMKEEDILDLLEQCEIDDEKLMGK 521          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFS-HFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFS 2786
            IR+PG++D E++ ++  I  NW++ +  VA+YWL  L++ K+ K++ IV+ ++  ++   +K   D+    + R+ ++V+NRLLW+RG GL  CF     SW+ IF+ S +++ PL+L  C R+V+LC  C+L+VY+++
Sbjct:  693 IRFPGKSDAESELLIEDIIDNWKYHKTKVASYWLIKLDSVKQRKVLDIVKTSIRTVLPRIWKV-PDVEEVNLYRIFNRVFNRLLWSRGQGLWNCFCDSGSSWESIFNKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYA 830          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWK----------LPQNAELT 1805
            +TANV GT+FEIV+ +++ +GF    DE  +T  LIW D+ + QE+IT+L++YQRINHF GM EI RKDFL +  +KM K RP DY + P+TW+FP E      Y+KE KK  K+K FI+KPANGAMG GI L    D + S +  IVQEYI+KP L++GYK D RIY+L+T CDPL+ F+Y +GLVR+ TEKY   ++  +  ++ HLTNYSVNK N  + R   E  GSK+S+      F      +    W  I ++VVKTL++ +PH++H YRMCR GQ    +SV FE+LGFDILLD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLNI+ S+K+K+L  QK +AQRRL       ++ P   ++  ++R  +E+RK++L + L++V+   S+E  ENRH+GN+ R++PP+DK + + Y  LL  +F  F        S  +    ++M       + REED+++ ++QCE ++  L+ K            +P+ AE+T
Sbjct:   41 ITANVAGTKFEIVRLVIDEMGFMKTPDED-ETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRKDFLARNMTKMIKSRPMDYTFVPRTWIFPSEYTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKVPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNERFERNETEDKGSKRSIK-WFTEFLQANQHDVTKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRTSDKRKNLAKQKAEAQRRLYGQNPVRRLSPG-SSDWEQQRHQLERRKEELKERLLQVRKQVSQEEHENRHMGNYRRIYPPEDKALLEKYEGLLAVAFQTF-------LSGRAASFQREMNNPL--KKMREEDLLDLLEQCEIDDEKLMGKTGRVRGPKPLCCMPECAEVT 541          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFS-HFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFS 2786
            IR+PG++D E++ ++  I  NW+H +  VA+YWL  L++ K+ K++ IV++++  ++   ++   D     + R+ ++V+NRLLW+ G GL  CF     SW+ IFS S +++ PL+L  C R+V+LC  C+L+VY+++
Sbjct:  718 IRFPGKSDAESELLIEDIMDNWKHYKTKVASYWLIKLDSVKQRKVLDIVKSSIRTVLPRIWRV-PDAEELSLYRIFNRVFNRLLWSHGQGLWSCFCDSGSSWESIFSKSPEVVTPLQLQCCQRLVELCKQCLLVVYKYT 855          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQ 1373
            +  N++  R+E V++  +  GF    ++   T Y  WTD  +S ER+ E+KSYQ+INHF GM EI RKD L +  S+M K+ PKD+ +FP+TW  P +    +  ++   +  K K +I KP +G  G GI +      IK  E  I Q YI KP ++DG+K D RIYVL+T CDPLR F+Y EGL R +T  Y+      +D I  HLTNYS+NK +SN++R   ++    +   S  + +    + N + +W+ I D+++KTL+   P + HNY  C      N  S  FEILGFDILLD  L PWLLEVN SPSF  D  LD++VK  LL DT  L+N++  +K+K L  ++Q+ Q
Sbjct:   61 LVINLSSCRYESVRRAAQQYGFREGGEDDDWTLY--WTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKMFPKDFRFFPRTWCLPAD----WGDLQTYSRSRKNKTYICKPDSGCQGKGIFITRTVKEIKPGEDMICQLYISKPFIIDGFKFDLRIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNFSR---DAHSGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLN--SACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEERQRGQ 408          

Query:  306 NVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTK---FNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREE 1718
            N+   ++E V++     G  +R+    +   L WTD  +S +R+ ++K YQ+INHF GM EI RKD L +  ++M KL PK+YN FP+TW  P +    Y   +   +  K K FI KP +G  G GI L      I+  E  I Q Y+ KP ++DG+K D RIYVL+T CDP R F+Y EGLVR  T  Y   +   ++ +  HLTNY++NK + N+ R  D  S  K      ++ FK      + +T+ LW  I D ++KTL+   P L HNY+ C         S  FEILGFD+LLD  L PWLLEVN SPSF  D  LDR+VK SLL DT  L+N+   +++K    +K++ + RL              N + + R +  ++ Q     L+        + +E +H+G F R+FP D    Y+ Y +    S +LF +      S    +  +Q LQ     Q ++E
Sbjct:   57 NLTNCKYESVRRAARRYG--IREAAEGEDWTLYWTDCSVSLDRVMDMKRYQKINHFPGMNEICRKDLLARNMNRMLKLFPKEYNIFPRTWCLPAD----YSDFQAYTRAKKHKTFICKPDSGCQGRGIYLTKSSKDIRPGEHMICQVYMSKPFIIDGFKFDLRIYVLVTSCDPFRVFMYDEGLVRFCTTHYTEPTVSNLEDVCMHLTNYAINKHSENFVRDEDTGSKRK------LSSFKKHMEDMSYDTEKLWTDIEDAIIKTLISAHPILKHNYQTCFPNHASG--SACFEILGFDVLLDRRLKPWLLEVNHSPSFTTDSRLDREVKDSLLYDTLVLINLGACDRRKITEEEKRRVKERLQ------------QNRSREARNEEPRQSQAASMELM--------QKYEAKHMGGFRRIFPRDGGEKYEKYFQ---HSSSLFQET---AASKAREECARQQLQELRLKQEQKE 490          

Query:  291 HQMTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEE 1757
            + ++AN++GTR++IV++++E  GFT+   E     YLIW DSF+S ERI+ELK +QRINHF GM EI RKD L +  +KM K  P+DY++ PKTW+ P E      Y ++ KK  K K FI KP+NGAMG GI LF   + I  NE  I+QEYIDKP L++G+K D RIYVLIT CDPLR F++ +GL+RL TEKY   +D  +D ++ HLTNYSVNK N  Y +    +    +      N +  + + +   LWK I +++VKTL++  PH++H YRMCR GQ  + DSV FE+LGFD++LD+ L PWL+E+NRSPSFG DE LD  +K SL+  T +LLNIK S+K+K++  QK + QRRL   + R  I+  + +E  KKR+ +E++K++L D+L R++  ++RE FENR+ GNF R+FPPDDK   + Y+ L+ D+F LF         +    + QQ +Q    N F+EEDI++ + QCEA+E
Sbjct:  299 YPVSANLSGTRYDIVRQMVEQAGFTISRHED-PMAYLIWNDSFVSTERISELKPFQRINHFPGMGEICRKDCLARNMAKMAKAHPEDYSFVPKTWILPSEYTAFQTYARDLKKKKKSKTFIAKPSNGAMGNGISLFRNTEKIPQNENIIIQEYIDKPLLIEGFKCDMRIYVLITSCDPLRVFLFNDGLLRLGTEKYVYPTDGNIDHLYMHLTNYSVNKHNDRYEKS-HTTDTGSKRSLKFFNDYLRRHDYDVSHLWKNITELIVKTLIVSLPHIMHAYRMCRPGQSPSSDSVCFELLGFDVMLDKKLRPWLIEINRSPSFGTDEKLDYDIKSSLVEHTLKLLNIKASDKRKNIAAQKAQTQRRLLRPSKR--IDKDM-SELDKKRQSVERKKEELKDMLTRIRKDATREDFENRNCGNFKRIFPPDDKFRREKYSSLITDAFNLF--------LSGRAASLQQEIQRAYSNTFKEEDILDMLAQCEADE 774          

Query: 2502 KIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCF-SHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSISLSQS 2804
            K+I IVR+NV  ++   +K S D+   R+ R+ ++V+NRLLW+ G GL  CF +   SW+ IFS S D I   E+  C R+VQLC DC+LIVYQF+     S
Sbjct:  790 KVIDIVRSNVRALLQRTWKIS-DVDTLRLFRIFTRVFNRLLWSHGQGLWNCFQTSGNSWETIFSKSSDTISASEMACCRRIVQLCRDCLLIVYQFAAEAKSS 890          

Query:  291 HQMTANVNGTRFEIVKKILESVGFTL-RDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLD-NETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEE 1757
            H +TAN++GTR+E+++ + E   F + ++D+     YLIW+DSF+S +RITELK +QRINHF GMVE++RKD L +   K+Q+   +++N+ PKTW+ P + +LL  Y K+ K   K + FI+KPANGA G GI+L+   + I  +E  IVQEYIDKP LL+GYK D RIYVL+T CDPLR FI+ +GLVR+ST+KY   +D  + +++ HLTNYSVNK N  Y +G D      +      N +  K + +T  LW++I D+VVKTL++ QPHL+H YRMCR G     DSV FE+LGFD+L+D+ L PWLLE+NRSPSFG DE +D  +K +L+ DT RLLNIK S+K+++ + QK +AQ+RL    FR+     +D +E  KKR +IEKRK++L + L RV+ +++RE FENR+ G F R+FP +DK     Y  ++   F +          +    A Q+ +Q    NQ+REEDI++ I +CEA+E
Sbjct:   73 HGITANLSGTRYEVIRLVCEKCKFDICKEDD--PNSYLIWSDSFVSADRITELKPFQRINHFPGMVEVTRKDCLARNMMKIQRHHAEEFNFVPKTWILPADHSLLQNYAKDLKAKKKYRTFIVKPANGAQGHGIQLYRNAEKIPPSEHFIVQEYIDKPLLLEGYKFDLRIYVLVTSCDPLRIFIFNDGLVRMSTDKYVNPADANLSNLYMHLTNYSVNKHNEYYQKG-DSVETGSKRSIRYFNEYLRKNDFDTMLLWRRIYDMVVKTLLVAQPHLLHAYRMCRPGAPPGSDSVCFEVLGFDVLIDKKLNPWLLEINRSPSFGTDEKIDFDIKSALIEDTVRLLNIKLSDKRRNYFAQKAEAQKRL----FRTTKRNEVDMSELEKKRLNIEKRKEELKEQLARVRKATAREDFENRNAGRFRRIFPSEDKLKQQKYVNIMSSIFGVV--------MSGRAPAMQKEIQKVYNNQWREEDILDMIAECEADE 548          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCF---SHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSI---SLSQSSTPRSDKSFAS 2837
            I++PG+TD E + +L  +  NW+  +  +A+YWL  L++ KR K+I IVR+NV  ++   ++ S D+   R+ R+ ++V+NRLLW+ G GL  CF   S   SW+ IFS S + I   E + C R+VQLC DC+LIVYQF+    S SQ ++  +D S A 
Sbjct:  705 IKFPGKTDQEAELILDTLHENWKFHKPRIASYWLVKLDSIKRRKVIDIVRSNVRAVLQRIWRIS-DVDNLRLYRIFTRVFNRLLWSHGQGLWNCFSTTSQNGSWETIFSKSSENICENEFNCCRRIVQLCRDCLLIVYQFAAEAKSTSQQNSENTDLSSAG 864          

Query:  297 MTANVNGTRFEIVKKILESVGFTL-RDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEEN 1760
            +TAN++ T+++IV+K     G  + RDD+   +C+ IW+DS +  ER  ELK YQRINHF GM EI RKD L +  +KM++  P +Y++ P+TW+ P E      Y +E KK  + K FI+KPANGAMG GI L    D I S+E  ++QEYID+P LLDGYK D R+YVL+T CDPLR F+Y +GLVRL TE Y   ++  MD +F HLTNYS+NK N N+ R  ++  GSK+S+  L N +    + + + LW+ I +++VKTL++ QPH++H+YRMCR G     DSV FE+LGFDILLD  L PWLLE+NRSPSFG D  LD++VKG  L DT RLLNIKPS++++ +  +K ++QRRL     RS+    + +E  KK+  + KR+ +L + L +++  S+RE FEN ++GNF RV+PPDD+   + Y  LL D+F LF          D  Q    +         REE+I++ ++QCEA+EN
Sbjct:    6 VTANISATKYDIVRKACVHAGMVVTRDDD--PSCFFIWSDSSVGAERFIELKPYQRINHFPGMGEICRKDSLARNIAKMKRAHPDEYSFAPQTWVLPAEYAAFQMYCRELKKKKRAKTFIMKPANGAMGNGISLIRNGDRIPSHEQLVIQEYIDRPFLLDGYKFDLRVYVLVTSCDPLRIFVYNDGLVRLGTECYEPPTEDNMDELFMHLTNYSINKHNENFERDENDDMGSKRSIKWL-NEWLQSMDYDVNFLWRGITEVIVKTLIVAQPHVLHSYRMCRPGAATGSDSVCFELLGFDILLDRKLKPWLLEINRSPSFGTDSKLDQEVKGGALRDTLRLLNIKPSDRRRGMAAEKAESQRRLLTQPKRSEYTMSV-SELDKKKMILNKRRNELKERLNQLRRESAREEFENINMGNFRRVYPPDDRAKNEKYTGLLADAFKLFLSGRAAALQKDGNQPFSTL---------REEEILDLLEQCEADEN 481          

Query:  297 MTANVNGTRFEIVKKILESVGFTL-RDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFR-SKIEPHLDNETLKKRK-DIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEE 1757
            +TAN+ GTR+E+V++++E  GF + RDD+     +L+W DSF+S E+I+ELK +QRINHF GM EI+RKD L +  +KM KL P +YN+ PKTW+ P + ++L  Y K+ K   K + FI+KP+ GA G GI L+   + I  +E  IVQEY+DKP LLDGYK D RIYVL+T CDPLR F++ +GLVRLSTEKY    D  +DS+F HLTNYS+NK + NY +  +E +GSK+++  L N +  K + +   LWK I D+++KTL++ +PH++H YRMCR GQ    DSV FEILGFDI LD  L PWLLE+NRSPSFG DE LD ++K  LL DT RLLN+K S+K+K+L  QK ++Q+RL     R S I   +D   L+K+K   E+RK++L  LL R++  ++RE FENR+ G F R+FPPDDK   D +  LL  +F+ F        S  +T  T+++ +++  N+ +E DI++ + QCEA+E
Sbjct:   70 VTANLAGTRYEVVREMVEKNGFHVSRDDD--PNSFLLWFDSFVSTEKISELKVFQRINHFPGMGEITRKDSLARNMAKMCKLHPDEYNFVPKTWILPADYSVLQNYAKDLKAKKKHRTFIVKPSTGAQGHGISLYKNAEKIPQSEHFIVQEYLDKPYLLDGYKFDLRIYVLMTSCDPLRIFLFNDGLVRLSTEKYIPPHDSNIDSLFMHLTNYSLNKHSENYEKDQNEDTGSKRTIRYL-NEYLRKEDKDVAWLWKNISDVIIKTLIVAEPHILHAYRMCRPGQQAGSDSVCFEILGFDIFLDRKLKPWLLEINRSPSFGTDEALDYRIKSGLLEDTLRLLNVKASDKRKNLAAQKAESQKRLFQQPSRKSDI---MDLSDLEKKKLSTERRKEELKGLLSRIRKDATREDFENRNCGRFRRIFPPDDKFHADKFTNLLTSAFSTF-------LSGKATTLTKEIERTYN-NKLKEADILDMLAQCEADE 545          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSH-FKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSI---SLSQSSTPRSDKSFASQS 2843
            I++PG+TD E + +L KI  NW+  +  +A+YWL  L++ KR K+I IVR+NV  ++   +K   D+ + R+ R+ ++V+NRLLW+ G GL  CF     SW+ IFS S D I   E++ C R+VQLC DC+LIVYQF+    +L+Q S+  ++++ ++++
Sbjct:  704 IKFPGKTDEEAEWILDKIQENWKFHKPRIASYWLVKLDSIKRRKVIDIVRSNVRAVLQRTWK-CPDVESLRLYRIFNRVFNRLLWSHGQGLWNCFGQSGNSWETIFSKSSDSISSTEMNCCRRIVQLCRDCLLIVYQFASDAKNLAQQSSSLNEETGSTKA 863          

Query:  297 MTANVNGTRFEIVKKILESVGFTL-RDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFR-SKIEPHLDNETLKKRK-DIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLF--NQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEE 1757
            +TAN+ GTR+E+V++++E  GF + RDD+     +L+W DSF+S E+I+ELK +QRINHF GM EI+RKD L +  +KM KL P +YN+ PKTW+ P + ++L  Y K+ K   K + FI+KP+ GA G GI L+   + I  +E  IVQEY+DKP LLDGYK D RIYVL+T CDPLR F++ +GLVRLSTEKY    D  +DS+F HLTNYS+NK + NY +  +E +GSK+++  L N +  K + +   LWK I D+++KTL++ +PH++H YRMCR GQ    DSV FEILGFDI LD  L PWLLE+NRSPSFG DE LD ++K  LL DT RLLN+K S+K+K+L  QK ++Q+RL     R S I   +D   L+K+K   E+RK++L  LL R++  ++RE FENR+ G F R+FPPDDK   D +  LL  +F+ F   +        + T   +  + S +     E DI++ + QCEA+E
Sbjct:   70 VTANLAGTRYEVVREMVEKNGFHVSRDDD--PNSFLLWFDSFVSTEKISELKVFQRINHFPGMGEITRKDSLARNMAKMCKLHPDEYNFVPKTWILPADYSVLQNYAKDLKAKKKHRTFIVKPSTGAQGHGISLYKNAEKIPQSEHFIVQEYLDKPYLLDGYKFDLRIYVLMTSCDPLRIFLFNDGLVRLSTEKYIPPHDSNIDSLFMHLTNYSLNKHSENYEKDQNEDTGSKRTIRYL-NEYLRKEDKDVAWLWKNISDVIIKTLIVAEPHILHAYRMCRPGQQAGSDSVCFEILGFDIFLDRKLKPWLLEINRSPSFGTDEALDYRIKSGLLEDTLRLLNVKASDKRKNLAAQKAESQKRLFQQPSRKSDI---MDLSDLEKKKLSTERRKEELKGLLSRIRKDATREDFENRNCGRFRRIFPPDDKFHADKFTNLLTSAFSTFLSGKATTLTKEIERTYNNKLKIPSLVGTDLTEADILDMLAQCEADE 555          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSH-FKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSI---SLSQSSTPRSDKSFASQS 2843
            I++PG+TD E + +L KI  NW+  +  +A+YWL  L++ KR K+I IVR+NV  ++   +K   D+ + R+ R+ ++V+NRLLW+ G GL  CF     SW+ IFS S D I   E++ C R+VQLC DC+LIVYQF+    +L+Q S+  ++++ ++++
Sbjct:  714 IKFPGKTDEEAEWILDKIQENWKFHKPRIASYWLVKLDSIKRRKVIDIVRSNVRAVLQRTWK-CPDVESLRLYRIFNRVFNRLLWSHGQGLWNCFGQSGNSWETIFSKSSDSISSTEMNCCRRIVQLCRDCLLIVYQFASDAKNLAQQSSSLNEETGSTKA 873          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXX-XXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEK 1775
            +TANV GT++EIV+  +  + F    DE  +T  LIW DS +  E+I EL++YQRINHF GM EI RKD L +  +KM K++P++Y++ PKTW+FP E      Y+KE ++  K+K FI+KPANGAMG GI L    + + + +  IVQEY+DKP L++GYK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   +D  +  ++ HLTNYSVNK N N+ R  DE+     +        F    + +    W  + ++VVKTL++ +PH++H YRMCR GQ    DSV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLN++ S+K+++L  QK +AQRRL       K+     +E  K+R  +E+RK++L + L +V+   SRE  E RH+GN+ R++PPDDK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ITANVAGTKYEIVRIAIREIDFHKTRDED-ETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMAKMIKIQPQEYSFSPKTWIFPAEYTQFQNYVKELRRKRKQKTFIVKPANGAMGHGISLIRNCEKLPAQDHFIVQEYLDKPFLMEGYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHTPNDSNLSQLYMHLTNYSVNKHNENFER--DETVDKGSKRSIGWFTEFLRTNDYDVAKFWGDVSELVVKTLIVAEPHVLHAYRMCRPGQPPGSDSVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDFDVKKGVLLNALKLLNVRASDKRRNLAQQKAEAQRRLYGQGTMKKLSAG-SSEWEKQRLTLERRKEELKERLAQVRKQISREEHEKRHLGNYRRIYPPDDKLLLEKYEGLLSAAFQTF------------LAGRAASLQKEMNNPLKRMKEEDILDLLEQCELDDEKLMGK 521          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCF-SHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQF 2783
            IR+PG+++ E +++L +I +NW++ +  VA+YWL  L+A K+ K++ IVR NV  ++   ++   D+ + R+ RL S+V+NRLLW+ G GL  CF S   SW+ IFS S +++   EL  C R+VQLC DC+L+VY+F
Sbjct:  662 IRFPGKSEEEAEAVLNEILNNWKYHKPKVASYWLVKLDATKQRKVLDIVRTNVRSVLQRIWR-EPDVDSLRLYRLFSRVFNRLLWSHGQGLWNCFCSSGSSWESIFSKSSEVVTTQELQCCQRLVQLCRDCLLVVYKF 798          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXX-XLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEK 1775
            +TANV GT++EIV+  +  + F    DE  +T  LIW DS +  E+I EL++YQRINHF GM EI RKD L +  +KM K++P++Y++ PKTW+FP E      Y+KE ++  K+K FI+KPANGAMG GI L    + + + +  IVQEY+DKP L++GYK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   +D  +  ++ HLTNYSVNK N N+ R  DE+       S      F    + +    W  + ++VVKTL++ +PH++H YRMCR GQ    DSV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLN++ S+K+++L  QK +AQRRL       K+     +E  K+R  +E+RK++L + L +V+   SRE  E RH+GN+ R++PPDDK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ITANVAGTKYEIVRIAIREIDFHKTRDED-ETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMAKMIKIQPQEYSFSPKTWIFPAEYTQFQNYVKELRRKRKQKTFIVKPANGAMGHGISLIRNCEKLPAQDHFIVQEYLDKPFLMEGYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHTPNDSNLSQLYMHLTNYSVNKHNENFER--DETVDKGSKRSIGWFTEFLRTNDYDVAKFWGDVSELVVKTLIVAEPHVLHAYRMCRPGQPPGSDSVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDFDVKKGVLLNALKLLNVRASDKRRNLAQQKAEAQRRLYGQGTMKKLSAG-SSEWEKQRLTLERRKEELKERLAQVRKQISREEHEKRHLGNYRRIYPPDDKLLLEKYEGLLSAAFQTF------------LAGRAASLQKEMNNPLKRMKEEDILDLLEQCELDDEKLMGK 521          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCF--SHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQF----SISLSQSSTPRSDKSFASQ 2840
            IR+PG+++ E +++L +I +NW++ +  VA+YWL  L+A K+ K++ IVR NV  ++   ++   D+ + R+ RL S+V+NRLLW+ G GL  CF  S   SW+ IFS S +++   EL  C R+VQLC DC+L+VY+F      SL+  S    D S  SQ
Sbjct:  730 IRFPGKSEEEAEAVLNEILNNWKYHKPKVASYWLVKLDATKQRKVLDIVRTNVRSVLQRIWR-EPDVDSLRLYRLFSRVFNRLLWSHGQGLWNCFCSSGRSSWESIFSKSSEVVTTQELQCCQRLVQLCRDCLLVVYKFVSDSHGSLTGLSPEWDDTSLVSQ 890          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXX-XLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEK 1775
            +TANV GT++EIV+  +  + F    DE  +T  LIW DS +  E+I EL++YQRINHF GM EI RKD L +  +KM K++P++Y++ PKTW+FP E      Y+KE ++  K+K FI+KPANGAMG GI L    + + + +  IVQEY+DKP L++GYK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   +D  +  ++ HLTNYSVNK N N+ R  DE+       S      F    + +    W  + ++VVKTL++ +PH++H YRMCR GQ    DSV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLN++ S+K+++L  QK +AQRRL       K+     +E  K+R  +E+RK++L + L +V+   SRE  E RH+GN+ R++PPDDK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ITANVAGTKYEIVRIAIREIDFHKTRDED-ETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMAKMIKIQPQEYSFSPKTWIFPAEYTQFQNYVKELRRKRKQKTFIVKPANGAMGHGISLIRNCEKLPAQDHFIVQEYLDKPFLMEGYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHTPNDSNLSQLYMHLTNYSVNKHNENFER--DETVDKGSKRSIGWFTEFLRTNDYDVAKFWGDVSELVVKTLIVAEPHVLHAYRMCRPGQPPGSDSVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDFDVKKGVLLNALKLLNVRASDKRRNLAQQKAEAQRRLYGQGTMKKLSAG-SSEWEKQRLTLERRKEELKERLAQVRKQISREEHEKRHLGNYRRIYPPDDKLLLEKYEGLLSAAFQTF------------LAGRAASLQKEMNNPLKRMKEEDILDLLEQCELDDEKLMGK 521          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCF--SHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSISLSQSS----TPRSDKSFASQSVISDYKESDLTSSFSVNSVTA 2906
            IR+PG+++ E +++L +I +NW++ +  VA+YWL  L+A K+ K++ IVR NV  ++   ++   D+ + R+ RL S+V+NRLLW+ G GL  CF  S   SW+ IFS S +++   EL  C R+VQLC DC+L+VY+F +S S  S    +P  D +     V S +     +SSF  N  +A
Sbjct:  730 IRFPGKSEEEAEAVLNEILNNWKYHKPKVASYWLVKLDATKQRKVLDIVRTNVRSVLQRIWR-EPDVDSLRLYRLFSRVFNRLLWSHGQGLWNCFCSSGRSSWESIFSKSSEVVTTQELQCCQRLVQLCRDCLLVVYKF-VSDSHGSLTGLSPEWDDTRYLLPVTSQFIIKWPSSSFGRNVASA 911          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXX-XLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEK 1775
            +TANV GT++EIV+  +  + F    DE  +T  LIW DS +  E+I EL++YQRINHF GM EI RKD L +  +KM K++P++Y++ PKTW+FP E      Y+KE ++  K+K FI+KPANGAMG GI L    + + + +  IVQEY+DKP L++GYK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   +D  +  ++ HLTNYSVNK N N+ R  DE+       S      F    + +    W  + ++VVKTL++ +PH++H YRMCR GQ    DSV FE+LGFDI+LD  L PWLLE+NR+PSFG D+ +D  VK  +L++  +LLN++ S+K+++L  QK +AQRRL       K+     +E  K+R  +E+RK++L + L +V+   SRE  E RH+GN+ R++PPDDK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ITANVAGTKYEIVRIAIREIDFHKTRDE-DETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMAKMIKIQPQEYSFSPKTWIFPAEYTQFQNYVKELRRKRKQKTFIVKPANGAMGHGISLIRNCEKLPAQDHFIVQEYLDKPFLMEGYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHTPNDSNLSQLYMHLTNYSVNKHNENFER--DETVDKGSKRSIGWFTEFLRTNDYDVAKFWGDVSELVVKTLIVAEPHVLHAYRMCRPGQPPGSDSVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDFDVKKGVLLNALKLLNVRASDKRRNLAQQKAEAQRRLYGQGTMKKLSAG-SSEWEKQRLTLERRKEELKERLAQVRKQISREEHEKRHLGNYRRIYPPDDKLLLEKYEGLLSAAFQTF------------LAGRAASLQKEMNNPLKRMKEEDILDLLEQCELDDEKLMGK 521          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCF--SHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQF 2783
            IR+PG+++ E +++L +I +NW++ +  VA+YWL  L+A K+ K++ IVR NV  ++   ++   D+ + R+ RL S+V+NRLLW+ G GL  CF  S   SW+ IFS S +++   EL  C R+VQLC DC+L+VY+F
Sbjct:  730 IRFPGKSEEEAEAVLNEILNNWKYHKPKVASYWLVKLDATKQRKVLDIVRTNVRSVLQRIWR-EPDVDSLRLYRLFSRVFNRLLWSHGQGLWNCFCSSGRSSWESIFSKSSEVVTTQELQCCQRLVQLCRDCLLVVYKF 867          

Query:  306 NVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIPSVN 1826
            N+   ++E V++     G  LR+    +   L WTD  +S +R+ ++K YQ+INHF GM EI RKD L +  ++M KL PKDYN FP+TW  P +    Y   +   +  K K +I KP +G  G GI L   +  I+  E  I Q Y+ +P ++DG+K D R+YVL+T CDP R F+Y EGL R  T  Y   +   M  +  HLTNY++NK + N+ R  D      +   S +N+       NT+ +W  I D+++KTL+   P L HNY  C         S  FEILGFD+LLD  L PWLLEVN SPSF  D  LDR+VK  LL DT  L+N+   +++K +  +K++ + RL              N + + R + E R+    ++          E +E++H+G F R++P +    Y+ Y      S +LF +      S    +  +Q LQ     + +EE      +  + E      K   P+ ++  +  P  N
Sbjct:   58 NLTNCKYESVRRAARKYG--LREAGEGEDWTLFWTDCSVSLDRVMDMKRYQKINHFPGMSEICRKDLLARNMNRMLKLFPKDYNIFPRTWCLPAD----YSDFQAYTRAKKHKMYICKPDSGCQGRGIFLTKSNKDIRPGEHMICQVYVSRPFIIDGFKFDLRVYVLVTSCDPFRIFVYNEGLARFCTNLYNEPTSSNMGDVCMHLTNYAINKHSENFVRDDD---TGSKRKLSTLNKHLEAMCYNTEKVWVDIEDVIIKTLISAHPILKHNYHTCFPNHASG--SACFEILGFDVLLDHRLKPWLLEVNHSPSFTTDSRLDREVKDGLLYDTLVLINLGACDRRKIMEEEKRRVKERLQ------------QNRSREARSE-ELRQSHATNM-------EQMERYESKHLGGFRRIYPREGGEKYEKY---FKHSSSLFQET---AASKAREECARQQLQEL---RLKEEQKGNHRRDLQGESAGERAK---PRKSQTHSTHPGTN 521          

Query:  318 TRFEIVKKILESVGFTLRDDEVFKTCY---LIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRP-KDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXL--MNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLN 1319
            T   +V+ IL S GF     EV  +     L+WT +      +  L  +Q++NHF    E++RKD L K   +MQ+    K +N  P T+L P E    Y+         +  + +   A+ + G G+ L +  + +  +E  +V  Y+  P L+D +K D R+YVL+T  +PL  ++Y EGL R +T KY   S   + + F HLTNYSVNKK+ +Y    D       +  S+  M R   +   +T AL  +I D++VKT++ V+  +  + RM             F ++G  +LL +    +LL ++ S +   D  LD KVK S++ D F L+ 
Sbjct:   72 TESRLVRNILGSHGF----HEVHPSSNDFNLMWTGTHPKPFSLRSLTDFQKVNHFPRSYELTRKDRLCKNVQRMQQSHGHKHFNIIPATFLLPAE----YQDFCSAHSKDRGPWIVKPVAS-SRGRGVYLVNSPNQVTMDENILVSRYLGNPLLIDDFKFDVRLYVLVTSYEPLVIYLYEEGLTRFATVKYDRNSKF-IKNQFMHLTNYSVNKKSRDYVSCDDPEVEDFGNKWSMSAMLRCLKQDGHDTTALMARIEDLIVKTILSVEQTIASSVRM-----FVPHRGNCFGMMGLGVLLYKRGRTFLLHLDLSLTLCSDAPLDLKVKASMVSDMFSLVG 396          

Query: 1038 INTDALWKQIIDIVVKTLVLVQP-------HLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVD 1301
            ++   +W+QI DI VKT++  +P         + N R C             E+ GFD++LDE L PWLLEVN SPS   +  LD  VK  L+ D
Sbjct:   14 VDCRTIWEQIKDIAVKTVIASEPFVSSLLAQFVGNRRSCH------------ELFGFDVMLDEKLKPWLLEVNISPSLHSNSPLDVAVKVQLIKD 96          

Query:  735 IVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLV-LVQPHLIHNYRMCRT---GQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSF 1250
            IVQ Y+  P LLDG K D R Y+LI    P    ++R G  RLS + Y+  S    + +  HLTN  + KK+  Y    +E+  +       M+RF    N +         D V+ T    +Q  + H +   ++   G+L  FD     ++G D L+DE+   WLLE+N +P+ 
Sbjct:  176 IVQRYVTNPLLLDGRKFDVRSYMLIASAAP-PIVLFRHGYARLSCQSYSPES----NDLTAHLTNQYMQKKSPVYQEVKEETVWT-------MSRFNDHVNEHCAPHKGLPKDWVLTTFTKRMQQVMTHCFLATKSKLEGKLGLFD-----LIGCDFLIDEDFKVWLLEMNCNPAL 334          

Query:  687 IRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNY-TRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFG-----------------MDETLDRKVKGSLLVDTFRLLNIKPS 1331
            +RL   D  +  +   IVQ+Y+++P L+   K D R + L+T  +PL  + Y++  +R ST+ + + +   +D+   HL N S+ K   N   R       +       ++  ++   +     W+ ++   +K  ++       +    R G        SFE+ G D LL E+  PWLLE+N SP+                   +   LDR+V  S     F L++ +P+
Sbjct:  321 LRLVECDTALVKDGRWIVQKYVERPLLIHATKFDIRQWFLVTDWNPLTVWFYQDCYLRFSTQPFQLDN---LDTSI-HLCNNSIQKHFENAQGRSAQLPRDNIWHGRQFVSYLES---LGLGFAWEGVVVPGMKQAIIHALQAAQDVVDARRG--------SFELYGADFLLGEDQRPWLLEINSSPTMSPSTPVTAELCARVQDDLLRVVLDRRVDRSAHTGGFYLIHKQPA 538          

Query:  687 IRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNY-TRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFG-----------------MDETLDRKVKGSLLVDTFRLLNIKPS 1331
            +RL   D  +  +   IVQ+Y+++P L+   K D R + L+T  +PL  + Y++  +R ST+ + + +   +D+   HL N S+ K   N   R       +       ++  ++   +     W+ ++   +K  ++       +    R G        SFE+ G D LL E+  PWLLE+N SP+                   +   LDR+V  S     F L++ +P+
Sbjct:  348 LRLVECDTALVKDGRWIVQKYVERPLLIHATKFDIRQWFLVTDWNPLTVWFYQDCYLRFSTQPFQLDN---LDTSI-HLCNNSIQKHFENAQGRSAQLPRDNIWHGRQFVSYLES---LGLGFAWEGVVVPGMKQAIIHALQAAQDVVDARRG--------SFELYGADFLLGEDQRPWLLEINSSPTMSPSTPVTAELCARVQDDLLRVVLDRRVDRSAHTGGFYLIHKQPA 565          

Query:  297 MTANVNGTRFEIVKKILESVGFTL-RDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEEN 1760
            +TAN++ T+++IV+K     G  + RDD+   +C+ IW+DS +  ER  ELK YQRINHF GM EI RKD L +  +KM++  P +Y++ P+TW+ P E      Y +E KK  + K FI+KPANGAMG GI L    D I S+E  ++QEYID+P LLDGYK D R+YVL+T CDPLR F+Y +GLVRL TE Y   ++  MD +F HLTNYS+NK N N+ R  ++  GSK+S+  L N +    + + + LW+ I +++VKTL++ QPH++H+YRMCR G     DSV FE+LGFDILLD  L PWLLE+NRSPSFG D  LD++VKG  L DT RLLNIKPS++++ +  +K ++QRRL     RS+    + +E  KK+  + KR+ +L + L +++  S+RE FEN ++GNF RV+PPDD+   + Y  LL D+F LF          D  Q    +         REE+I++ ++QCEA+EN
Sbjct:    6 VTANISATKYDIVRKACVHAGMVVTRDDD--PSCFFIWSDSSVGAERFIELKPYQRINHFPGMGEICRKDSLARNIAKMKRAHPDEYSFAPQTWVLPAEYAAFQMYCRELKKKKRAKTFIMKPANGAMGNGISLIRNGDRIPSHEQLVIQEYIDRPFLLDGYKFDLRVYVLVTSCDPLRIFVYNDGLVRLGTECYEPPTEDNMDELFMHLTNYSINKHNENFERDENDDMGSKRSIKWL-NEWLQSMDYDVNFLWRGITEVIVKTLIVAQPHVLHSYRMCRPGAATGSDSVCFELLGFDILLDRKLKPWLLEINRSPSFGTDSKLDQEVKGGALRDTLRLLNIKPSDRRRGMAAEKAESQRRLLTQPKRSEYTMSV-SELDKKKMILNKRRNELKERLNQLRRESAREEFENINMGNFRRVYPPDDRAKNEKYTGLLADAFKLFLSGRAAALQKDGNQPFSTL---------REEEILDLLEQCEADEN 481          

Query:  297 MTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQ 1631
            ++  +   +++ V+++ +  G     +E      L W D  ++ ER  E+K YQ+INHF GM EI RKD L +  +++ K  PKDY  FPKTW+ P +    Y   +   +  K K FI KP +G+ G GI +      IK  E  + Q+Y+ KP L+DG+K D RIYVL+T CDPLR F+Y +GL R +T KY    +  +D I  HLTNYS+NK + ++ R  DE  GSK+ ++++ N F  +   +   +W  I D ++KTLV   P L HNYR C      N  S  FEILGFD+LLD+ L PW++EVN SPSF  D  LD+++K  L+ D   LLN    +++K +   K++ + RL L   R K EP        KR D E ++          Q +     +E++H+G + R++P  ++   + YA    +S +LF +
Sbjct:    2 LSVCLTNCKYDSVRRVTKRFGMKEVGEE--DDWSLFWIDCSVALERCMEMKRYQKINHFPGMSEICRKDLLARNMNRLWKQFPKDYAVFPKTWVLPAD----YGDFQSYCRQKKNKTFITKPESGSQGKGIVITKNPKDIKPGEHLVCQQYVSKPFLIDGFKFDLRIYVLVTSCDPLRVFVYEDGLARFATSKYTEPQNNNLDDICMHLTNYSINKHSKDFIR--DEEIGSKRRITTINNWF-VENGYDLKEIWDGIEDCIIKTLVTAHPILKHNYRTCFPN--HNKGSACFEILGFDVLLDKKLKPWVIEVNHSPSFTTDSPLDKEIKEGLMSDALALLNFGACDRRKIIEEDKRRVRERL-LQKQRPK-EP--------KRDDCENQQ----------QYNEWITKYEDKHLGKYRRIYPQGNE---EKYARFFENSCSLFQE 412          

Query:  318 TRFEIVKKILESVGFTLRDDEVFKTCY-LIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRP-KDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDG---------YKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXL--MNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNI--------KPSNKQ--------KSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELL 1604
            T  ++V+ IL S  F  R+     + + L+WT S +    +  ++ +Q+INHF    E++RKD L K   ++Q  +  K +++ P +++ P+E N  Y    + +     K         + G GI L S    +  ++  +V  YI  P L+DG         +K D R+YV +TC DPLR ++Y EGL R +T KY  +     +S   HLTNYSVNKK+ N+    D       +  S+  M RF     I+T AL  +I D+VVKT++  +  +    +M             FEI GFDIL+DENL PWLLEVN SPS   D  LD K+K  L+ D F L+          +P+  +        ++  +QKQ+ Q    L+   S + P        +RK +++ +  L     R+   +  EY      G F+R+FP  +   ++ Y   L
Sbjct:   15 TECKLVRSILNSHAF--REVHPNSSNFNLMWTGSHLKPHSLRGMQDFQKINHFPRSYELTRKDRLYKNIQRLQHSKGLKHFDFIPNSFVLPEEYNEFYAAFMKERGHWIVKP-----VASSRGRGIFLISHPSQVPLDDHLLVCRYITNPLLIDGNIYCFNFIGFKFDVRLYVGVTCYDPLRIYLYEEGLSRFATVKYDKSGKNIRNSCM-HLTNYSVNKKSENFVSCQDPEVEDYGNKWSMSAMLRFIKHKGIDTTALMMRIEDVVVKTIIAGELPIASACKM-----FMPHPGNCFEIYGFDILIDENLRPWLLEVNLSPSLACDSPLDLKIKSHLVTDMFNLIGFVAHDPLIRRPNGTRRVPDYAAARNKKYQKQRTQSAGALST--SGLRP---TSAAARRKAVDE-ELTLTPEESRILRQTKEEYARR---GGFVRIFPSSES--WELYGSFL 448          

Query:  441 ELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPK-DYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSN-YTRGVDEXXXXXXXX---XXLMNRFKTKFNINTDALWKQIIDIVVKTLV----LVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKK------RKDIEKRKQDLIDLL----VRVQASSSREYFENRHVGNFLRVFP 1562
             ++ YQ++NHF G  +I RKD L +  SKM     K ++ + P+T++ P +  LL    +   +   ++ +ILKP   A G+GIR+  +   I    P IVQ+Y+ KP L++G K D RIYV +T  DPLR +I+ +GLVR +T KY+ +S   + + F HLTNYSVNKKN   Y    D+S           SL   FK +  IN   +W  + D++VK ++     V   +  N R           S   E+ G D++LDENL PWLLEVN SPS   +  LDR +KG ++ D   L+N+      ++L      +   L  +  + K    L ++   K      R   E+ +Q ++D+L    VR+   +  EY      G F R FP
Sbjct:   81 SIREYQKVNHFPGTFQIGRKDRLWRNLSKMMVHHGKKEFGFLPQTYVLPYDFKLL---KRAWDEGGSRQKWILKPPASARGIGIRVIHKWTQIPRKRPVIVQKYLHKPFLINGSKFDLRIYVYVTSYDPLRIYIFEDGLVRFATCKYS-SSVKSLSNRFMHLTNYSVNKKNEGAYQSNADDSLCQGHKWYYLKSLWGYFK-RMGINHAQVWDSVKDVIVKAIIASDSFVNTLIKQNVR---------HRSCCHELFGCDVMLDENLKPWLLEVNISPSLHSNSQLDRNIKGQMIRD---LMNLAAFRIPENLVTTTTASASSLN-SFVQDKSTTSLSSDERAKHAFYVGRNVDERTRQSILDILTPSDVRILMETEDEYSRR---GCFQRAFP 452          

Query:  327 EIVKKILESVGFTLRDDEVF---KTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKD-YNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLN 1319
            E+++ +    G+   D+E      T  L W  S        + + +QR+NHF     I+RKD L +   +M+ +     +N+ P ++  P +    +      KK   K  +I KPA+ + G GI LF     +  +  ++VQ YI  P L+ GYK D R+YVL+T   PL  ++Y EG+VR STEK+ +++   + ++F HLTN S+NK+  +Y+   +      +   S +  +  + NI    LW +I  I++ TL+   P +  +   C            FE+ GFDIL+DENL PWLLEVN SPS G D  +D  +K  LL DTF LLN
Sbjct:   14 ELLRDVCLERGWHEFDEEAVDPDATWSLWWKSSGFRTGEYEDCRPWQRLNHFPKTSAITRKDCLARNLRRMRGVYGNYLFNFAPLSFNLPNDYRK-FVAEYSKKKDATKNIWICKPADLSRGRGIFLFENLLDLTYDSAAVVQRYISSPLLICGYKFDLRLYVLVTSFHPLCIYVYHEGMVRFSTEKFDLST---LSNLFSHLTNSSINKQGPSYSLDKERIGTGCKWTLSQLRAYFHQHNIGDGMLWHRINTIIILTLLTQAPEVSKSCTNC------------FELYGFDILIDENLKPWLLEVNFSPSLGSDCLVDLTIKKPLLNDTFELLN 332          

Query:  297 MTANVNGTRFEIVKKILESVGFT-LRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXX-XLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEK 1775
            ++ANV GT++EIV+ ++  + F   RDD+  +T  LIW DS +  E+I EL++YQRINHF GM EI RKD L +  SKM K +P++Y++ PKTW+FP E   L  Y+KE ++  K+K FI+KP+NGAMG GI L    + + + E  IVQEY+DKP L++GYK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   S+  +  ++ HLTNYSVNK N N+ R  DE+       S S   +F    + +    W  I ++VVKTL++ +PH++H YRMCR GQ    DSV FE+LGFDI+LD  L PWLLE+NR+PSF  D+ +D  VK   L++  +LLNI+ S+K+++L  QK +AQRRL       K+ P   ++  K+R  +E+R+++L + L +V+   SRE  E +H+GN+ R++PPDDK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ISANVAGTKYEIVRIVINEMDFIKARDDD--ETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMSKMIKCQPQEYSFIPKTWIFPAEYTQLQNYVKELRRKRKQKTFIVKPSNGAMGHGIWLIRNCEKLPAQEHFIVQEYLDKPFLMEGYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHAPSEANLSQLYMHLTNYSVNKHNENFER--DETVDKGSKRSISWFTQFLRCNDYDVAKFWGDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSDSVCFEVLGFDIILDHKLKPWLLEINRAPSFATDQKIDYDVKKGALLNALKLLNIRASDKKRNLAQQKAEAQRRLYGHGSMKKL-PAASSDWEKQRHTLERRREELKEQLAQVRKQFSREQHEKQHLGNYRRIYPPDDKLLLEKYESLLSAAFQTF------------LAGRAASLQKEMNNPLKRMKEEDILDLLEQCELDDEKLMGK 521          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSHFKSWQLI 2684
            IR+PG+T+ E +++L +I  NW++ +  VA+YWL  L++ K+ K++ IVR NV   +   ++   D+ +  + RL ++V+NRLLW+ G GL  CFS+   W  +
Sbjct:  731 IRFPGKTEEEAEAVLDEILDNWKYHKPKVASYWLVKLDSTKQRKVLDIVRTNVRLALQRIWR-EPDVESLHLYRLFNRVFNRLLWSHGQGLWNCFSNTGYWNAV 833          

Query:  297 MTANVNGTRFEIVKKILESVGFT-LRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXX-XLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEK 1775
            ++ANV GT++EIV+ ++  + F   RDD+  +T  LIW DS +  E+I EL++YQRINHF GM EI RKD L +  SKM K +P++Y++ PKTW+FP E   L  Y+KE ++  K+K FI+KP+NGAMG GI L    + + + E  IVQEY+DKP L++GYK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   S+  +  ++ HLTNYSVNK N N+ R  DE+       S S   +F    + +    W  I ++VVKTL++ +PH++H YRMCR GQ    DSV FE+LGFDI+LD  L PWLLE+NR+PSF  D+ +D  VK   L++  +LLNI+ S+K+++L  QK +AQRRL       K+ P   ++  K+R  +E+R+++L + L +V+   SRE  E +H+GN+ R++PPDDK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ISANVAGTKYEIVRIVINEMDFIKARDDD--ETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMSKMIKCQPQEYSFIPKTWIFPAEYTQLQNYVKELRRKRKQKTFIVKPSNGAMGHGIWLIRNCEKLPAQEHFIVQEYLDKPFLMEGYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHAPSEANLSQLYMHLTNYSVNKHNENFER--DETVDKGSKRSISWFTQFLRCNDYDVAKFWGDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSDSVCFEVLGFDIILDHKLKPWLLEINRAPSFATDQKIDYDVKKGALLNALKLLNIRASDKKRNLAQQKAEAQRRLYGHGSMKKL-PAASSDWEKQRHTLERRREELKEQLAQVRKQFSREQHEKQHLGNYRRIYPPDDKLLLEKYESLLSAAFQTF------------LAGRAASLQKEMNNPLKRMKEEDILDLLEQCELDDEKLMGK 521          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSH-FKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSISLSQSS 2807
            IR+PG+T+ E +++L +I  NW++ +  VA+YWL  L++ K+ K++ IVR NV   +   ++   D+ +  + RL ++V+NRLLW+ G GL  CFS+   SW+ IFS S ++  P EL  C R+VQLC DC+L+VY+F +S S+ S
Sbjct:  731 IRFPGKTEEEAEAVLDEILDNWKYHKPKVASYWLVKLDSTKQRKVLDIVRTNVRLALQRIWR-EPDVESLHLYRLFNRVFNRLLWSHGQGLWNCFSNTGSSWETIFSKSSEVASPQELQCCRRLVQLCRDCLLVVYKF-VSESRGS 874          

Query:  297 MTANVNGTRFEIVKKILESVGFT-LRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXX-XLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPN---QFREEDIMEQIKQCEAEENALLEK 1775
            ++ANV GT++EIV+ ++  + F   RDD+  +T  LIW DS +  E+I EL++YQRINHF GM EI RKD L +  SKM K +P++Y++ PKTW+FP E   L  Y+KE ++  K+K FI+KP+NGAMG GI L    + + + E  IVQEY+DKP L++GYK D RIY+L+T CDPLR F+Y +GLVR+ TEKY   S+  +  ++ HLTNYSVNK N N+ R  DE+       S S   +F    + +    W  I ++VVKTL++ +PH++H YRMCR GQ    DSV FE+LGFDI+LD  L PWLLE+NR+PSF  D+ +D  VK   L++  +LLNI+ S+K+++L  QK +AQRRL       K+ P   ++  K+R  +E+R+++L + L +V+   SRE  E +H+GN+ R++PPDDK + + Y  LL  +F  F                   LQ  M N   + +EEDI++ ++QCE ++  L+ K
Sbjct:   41 ISANVAGTKYEIVRIVINEMDFIKARDDD--ETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLARNMSKMIKCQPQEYSFIPKTWIFPAEYTQLQNYVKELRRKRKQKTFIVKPSNGAMGHGIWLIRNCEKLPAQEHFIVQEYLDKPFLMEGYKFDLRIYILVTSCDPLRIFLYNDGLVRMGTEKYHAPSEANLSQLYMHLTNYSVNKHNENFER--DETVDKGSKRSISWFTQFLRCNDYDVAKFWGDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSDSVCFEVLGFDIILDHKLKPWLLEINRAPSFATDQKIDYDVKKGALLNALKLLNIRASDKKRNLAQQKAEAQRRLYGHGSMKKL-PAASSDWEKQRHTLERRREELKEQLAQVRKQFSREQHEKQHLGNYRRIYPPDDKLLLEKYESLLSAAFQTF------------LAGRAASLQKEMNNPLKRMKEEDILDLLEQCELDDEKLMGK 521          

Query: 2373 IRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSH-FKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSISLSQSS 2807
            IR+PG+T+ E +++L +I  NW++ +  VA+YWL  L++ K+ K++ IVR NV   +   ++   D+ +  + RL ++V+NRLLW+ G GL  CFS+   SW+ IFS S ++  P EL  C R+VQLC DC+L+VY+F +S S+ S
Sbjct:  731 IRFPGKTEEEAEAVLDEILDNWKYHKPKVASYWLVKLDSTKQRKVLDIVRTNVRLALQRIWR-EPDVESLHLYRLFNRVFNRLLWSHGQGLWNCFSNTGSSWETIFSKSSEVASPQELQCCRRLVQLCRDCLLVVYKF-VSESRGS 874          

Query:  399 LIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREE 1718
            L+WTD  +S +R+ ++K YQ+INHF GM EI RKD L +  ++M KL PKDYN FPKTW  P +    Y   +   +  K K +I KP  G  G GI +      I+  E  I Q YI KP ++DGYK D RIYVL+T CDP   F++REGL R  T KY   +   ++ +  HLTNYS+NK + N+ R  D      +   S +NR     N NT+ +W+ I DI++KTL+   P L HNY  C         S  FEILGFD+LLD  L PW+LEVN SPSF  D  LDR+VK +LL DT  L+N+   ++ K    ++++A+ RL               +T  K    E R Q+L             E +E +++G F +++P  +   YD Y      S +LF +      S    +  +Q LQ     Q ++E
Sbjct:   84 LLWTDCSVSLDRVKDMKCYQKINHFPGMNEICRKDSLARNLNRMLKLFPKDYNIFPKTWCLPAD----YSDFQVYTRAKKSKTYICKPDTGCQGKGIFITKSSKDIQHEEHMICQVYISKPLIIDGYKFDLRIYVLVTSCDPFSIFMFREGLARFCTSKYNEPTRTNVEHVCMHLTNYSINKNSENFVRDED---TGSKRKLSTLNRHLESLNCNTEKMWEDIEDIIIKTLISAHPILKHNYHTCFPNHTAG--SACFEILGFDVLLDHRLKPWVLEVNHSPSFTTDSQLDREVKDALLYDTLVLINLAACDRHKITKEERRRAKDRL--------------QQTCSK----EARAQELRQ--SHAVTVEQMEEYEAKNLGGFKKIYPRKEGEKYDKY---FKHSRSLFQETTA---SKAREECARQQLQDLQVKQEQKE 488          

Query:  399 LIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQES-------------NLL------------YXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREE 1718
            L+WTD  +S +R+ ++K YQ+INHF GM EI RKD L +  ++M KL PKDYN FPKTW  P ES             N +            Y   +   +  K K +I KP  G  G GI +      I+  E  I Q YI KP ++DGYK D RIYVL+T CDP   F++REGL R  T KY   +   ++ +  HLTNYS+NK + N+ R  D      +   S +NR     N NT+ +W+ I DI++KTL+   P L HNY  C         S  FEILGFD+LLD  L PW+LEVN SPSF  D  LDR+VK +LL DT  L+N+   ++ K    ++++A+ RL               +T  K    E R Q+L             E +E +++G F +++P  +   YD Y      S +LF +      S    +  +Q LQ     Q ++E
Sbjct:   84 LLWTDCSVSLDRVKDMKCYQKINHFPGMNEICRKDSLARNLNRMLKLFPKDYNIFPKTWCLPAESVSTLFEFRPFSYINFILFLICCPILLHSYSDFQVYTRAKKSKTYICKPDTGCQGKGIFITKSSKDIQHEEHMICQVYISKPLIIDGYKFDLRIYVLVTSCDPFSIFMFREGLARFCTSKYNEPTRTNVEHVCMHLTNYSINKNSENFVRDED---TGSKRKLSTLNRHLESLNCNTEKMWEDIEDIIIKTLISAHPILKHNYHTCFPNHTAG--SACFEILGFDVLLDHRLKPWVLEVNHSPSFTTDSQLDREVKDALLYDTLVLINLAACDRHKITKEERRRAKDRL--------------QQTCSK----EARAQELRQ--SHAVTVEQMEEYEAKNLGGFKKIYPRKEGEKYDKY---FKHSRSLFQETTA---SKAREECARQQLQDLQVKQEQKE 517          

Query:   99 MLSNNYHPNLQPRQGQNGIGNLEHDHIVSYLNHSKRLNGVPISEKDXXXXXXXXXXXXXXXXXXHQMTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIPSVNYYXXXXXXXXXXXXXXXXXXXXXXXXXXIIGEYESYSANKKPTNIQLNNTXXXXXXXXXXXXXXFRPKSVLXXXXXXXXXXXXXEHTLKYSDLNKAKPFKKTKLPNKALKSKESSRVHXXXXXXXXXXXXXKDFNKTDEEVPSKYDLCYLSDSPAPLKDNFSRSPIYEEXXXXXXXXXXXXXIRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSISLSQSSTPRSDKSFASQSVISDYKESDLTSSFSVNSVTA 2906
            MLSNNYHPNLQPRQGQNGIGNLEHDHIVSYLNHSKRLNGVPISEKDRAEREKRIQKKKAKKRQKHQMTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYKYIKETKKPTKKKYFILKPANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDESSGSKQSLSSLMNRFKTKFNINTDALWKQIIDIVVKTL+LVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIPSVN+YETSSEEDTTSSNESASDSDANNLSDDIIGEYESYSANKKPTNIQLNNTNRKNANSKPINNNNFRPK VLRPSTSTPRPNSNSEHTLKYSDLNKAKP KKTKLPNKALKSKESSRVHSPFSQSSQISSRSKDFNKTDEEVPSKYD CYLSDSPAPLKDNFSRSPIYEELLKILLTSLTTLTIRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSISLSQSSTPRSDKSFASQSVISDYKESDLTSSFSVNSVTA
Sbjct:    1 MLSNNYHPNLQPRQGQNGIGNLEHDHIVSYLNHSKRLNGVPISEKDRAEREKRIQKKKAKKRQKHQMTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYKYIKETKKPTKKKYFILKPANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDESSGSKQSLSSLMNRFKTKFNINTDALWKQIIDIVVKTLILVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIPSVNFYETSSEEDTTSSNESASDSDANNLSDDIIGEYESYSANKKPTNIQLNNTNRKNANSKPINNNNFRPKFVLRPSTSTPRPNSNSEHTLKYSDLNKAKPVKKTKLPNKALKSKESSRVHSPFSQSSQISSRSKDFNKTDEEVPSKYDGCYLSDSPAPLKDNFSRSPIYEELLKILLTSLTTLTIRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSISLSQSSTPRSDKSFASQSVISDYKESDLTSSFSVNSVTA 936          

Query: 1128 MCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIPSVNYYXXXXXXXXXXXXXXXXXXXXXXXXXXIIGEYESYSANKKPTNIQLNNTXXXXXXXXXXXXXXFRPKSVLXXXXXXXXXXXXXEHTLKYSDLNKAKPFKKTKLPNKALKSKESSRVHXXXXXXXXXXXXXKDFNKTDEEVPSKYDLCYLSDSPAPLKDNFSRSPIYEEXXXXXXXXXXXXXIRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSISLSQSSTPRSDKSFASQSVISDYKESDLTSSFSVNSVTA 2906
            MCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIPSVN+YETSSEEDTTSSNESASDSDANNLSDDIIGEYESYSANKKPTNIQLNNTNRKNANSKPINNNNFRPK VLRPSTSTPRPNSNSEHTLKYSDLNKAKP KKTKLPNKALKSKESSRVHSPFSQSSQISSRSKDFNKTDEEVPSKYD CYLSDSPAPLKDNFSRSPIYEELLKILLTSLTTLTIRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSISLSQSSTPRSDKSFASQSVISDYKESDLTSSFSVNSVTA
Sbjct:    1 MCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYYAELLVDSFTLFNQLNYQNCSTDSTQATQQMLQSFMPNQFREEDIMEQIKQCEAEENALLEKWKLPQNAELTTIIPSVNFYETSSEEDTTSSNESASDSDANNLSDDIIGEYESYSANKKPTNIQLNNTNRKNANSKPINNNNFRPKFVLRPSTSTPRPNSNSEHTLKYSDLNKAKPVKKTKLPNKALKSKESSRVHSPFSQSSQISSRSKDFNKTDEEVPSKYDGCYLSDSPAPLKDNFSRSPIYEELLKILLTSLTTLTIRYPGQTDVETKSMLAKIFSNWEHQRHSVATYWLATLNAKKRDKIIQIVRNNVDKIINDNFKFSADISAARVNRLISKVYNRLLWNRGNGLIQCFSHFKSWQLIFSHSGDLIKPLELDICSRVVQLCLDCVLIVYQFSISLSQSSTPRSDKSFASQSVISDYKESDLTSSFSVNSVTA 593          

Query:   99 MLSNNYHPNLQPRQGQNGIGNLEHDHIVSYLNHSKRLNGVPISEKDXXXXXXXXXXXXXXXXXXHQMTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLD 773
            MLSNNYHPNLQPRQGQNGIGNLEHDHIVSYLNHSKRLNGVPISEKDRAEREKRIQKKKAKKRQKHQMTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYKYIKETKKPTKKKYFILKPANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLD
Sbjct:    1 MLSNNYHPNLQPRQGQNGIGNLEHDHIVSYLNHSKRLNGVPISEKDRAEREKRIQKKKAKKRQKHQMTANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYKYIKETKKPTKKKYFILKPANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLD 225          

Query:  300 TANVNGTRFEIVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPKDYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXXXXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLLNIKPSNKQKSLYFQKQKAQRRLTLAAFRSKIEPHLDNETLKKRKDIEKRKQDLIDLLVRVQASSSREYFENRHVGNFLRVFPPDDKTVYDYY 1592
            T  ++  ++E V+++ +  GF   ++E      LIWTD  ++ ER+  +K YQ+INH+ GM+EI RKD L +  ++M KL  K+YN  PK+W  P +    Y  ++   +  K K +ILKP  G  G GI +      IK +E  + Q Y+ KP L+DG+K D RIYVL+T CDPLR F Y++GLVR +T KY+  +   +D+I+ HLTNYS+ K + N+ +  D+  G  +   + +NR+      N + +W  + DI++KTL+     L HNYR C    ++   S  FEILGFD++ D  L P L+EVN SPSF  D  LD+++K +L+ DT +L+N   ++K++ +  +K+K + RL     R  I+  +D E  K                + +Q     E +E+ H+GNF R++P    + YD +
Sbjct:  121 TICLSNCKYESVRRVSKRFGFREVNEE--DDWNLIWTDFSVNMERVNGMKKYQKINHYPGMLEICRKDSLARNMNRMVKLFGKEYNIAPKSWCLPAD----YAELQAYARQKKHKTYILKPDAGCQGRGIWITKNPKEIKPSENMVCQVYLSKPFLIDGFKFDLRIYVLVTSCDPLRVFAYKDGLVRFTTTKYSEPNFNNVDNIYMHLTNYSLQKHSDNFVQ--DDEEGGTKRRITTLNRWFHDKGYNIEKIWTDVDDIIIKTLISAHTLLKHNYRTCFPNHVRG--SACFEILGFDVIFDRKLKPSLVEVNHSPSFHTDSKLDKEIKEALIWDTLQLVNFAAADKKRIIDEEKRKIRERLFQKQNRKDIKDEVDKEMAK---------------FMEIQ-----EKYEDGHLGNFRRIYPGPGSSKYDKF 521          

Query:  330 IVKKILESVGFTLRDDEVFKTCYLIWTDSFISQERITELKSYQRINHFMGMVEISRKDFLTKKFSKMQKLRPK--DYNYFPKTWLFPQESNLLYXXXXXXXXXXXXXXXXXXXANGAMGMGIRLFSEDDIIKSNEPSIVQEYIDKPCLLDGYKNDFRIYVLITCCDPLRAFIYREGLVRLSTEKYAMTSDLKMDSIFKHLTNYSVNKKNSNYTRGVDEXXXXXX--XXXXLMNRFKTKFNINTDALWKQIIDIVVKTLVLVQPHLIHNYRMCRTGQLQNFDSVSFEILGFDILLDENLCPWLLEVNRSPSFGMDETLDRKVKGSLLVDTFRLL 1316
            +VK+ ++  GF L +    K  ++ +  S +       +  +Q+INH  G  +I RKD L +  + +   + K  ++N+ PKT+  P +  LL +   + +   K K+ +  PA  A G+G+R+ S+   +     +++Q YI +P L++  K D RIYV IT CDPLR ++YREGLVR ++ KY+ +S   + + F HLTNYSVNKKNS+Y    D +       +L +L   F+    I+   +WK I D ++KT++ V+ H+  N +M  T +     +  +E+ GFD+LLD NL PW+LEVN SPS   +  LD +VK SL+ D F L+
Sbjct:  361 VVKRAVKRSGFKLTNKSGVK--WIGYFGSHLKSSGFRTINEHQKINHMPGSFQIGRKDRLWRNVTALSSKKSKIHEFNFLPKTYCLPADLKLLKRIWDDEESRKKAKWILKPPA-AARGIGVRVISKWSQVPKKRAALIQNYISRPFLINDSKFDLRIYVAITSCDPLRIYVYREGLVRFASHKYSKSSK-NISNRFIHLTNYSVNKKNSDYLNNEDHNKCQGHKWTLQTLWRHFEQDLRIDWIPIWKNIKDCIIKTIISVESHINSNIKMFCTNK-----NCVYELFGFDVLLDHNLKPWVLEVNVSPSLHSNSPLDIEVKSSLIADLFNLV 684