slc47a-5
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30022038 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of slc47a-5 vs. Ensembl Human
Match: SLC47A1 (solute carrier family 47 member 1 [Source:HGNC Symbol;Acc:HGNC:25588]) HSP 1 Score: 236.498 bits (602), Expect = 2.436e-69 Identity = 151/500 (30.20%), Postives = 257/500 (51.40%), Query Frame = 3
Query: 96 SEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIG---NTVGLSTLMIGYVISVWFFNWETLALDA---AHRLTRGQYEDQNEIFEKNPLLITKPKENE--------KVNYPNGPYQLKHNR 1553
S + + RAL++L GP F + FLI+ +F G L K++LD V ++VI++ G SVG+GL+ ACDTL SQ YGS + K G LQ+S + LL FP A+ LN H+LLLF QDP + ++ Y++ ++PA P + Y + +YL NQ P +V + N+ N A YL L++ + SA+ +I+ +A+ Y++ K ++ TW GW++ L +W FLRLAIP + E +E F++GI+G+V + S++ + + + + A+V++G LGAG E+A+K + +S++ V+ ++ ++ +++ IFTTD+ + V++++ Y + + E++ G++RG + + Y++GLP+ L F L V GLW G TV + +G++I NW+ A A+ N ++PL P+ E K P Q++
Sbjct: 29 SAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAVINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWSLECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGLWSGIIICTVFQAVCFLGFIIQ---LNWKKACQQAQVHANLKVNNVPRSGNSALPQDPLHPGCPENLEGILTNDVGKTGEPQSDQQMRQEE 525
BLAST of slc47a-5 vs. Ensembl Human
Match: SLC47A1 (solute carrier family 47 member 1 [Source:HGNC Symbol;Acc:HGNC:25588]) HSP 1 Score: 235.728 bits (600), Expect = 7.124e-69 Identity = 151/500 (30.20%), Postives = 257/500 (51.40%), Query Frame = 3
Query: 96 SEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIG---NTVGLSTLMIGYVISVWFFNWETLALDA---AHRLTRGQYEDQNEIFEKNPLLITKPKENE--------KVNYPNGPYQLKHNR 1553
S + + RAL++L GP F + FLI+ +F G L K++LD V ++VI++ G SVG+GL+ ACDTL SQ YGS + K G LQ+S + LL FP A+ LN H+LLLF QDP + ++ Y++ ++PA P + Y + +YL NQ P +V + N+ N A YL L++ + SA+ +I+ +A+ Y++ K ++ TW GW++ L +W FLRLAIP + E +E F++GI+G+V + S++ + + + + A+V++G LGAG E+A+K + +S++ V+ ++ ++ +++ IFTTD+ + V++++ Y + + E++ G++RG + + Y++GLP+ L F L V GLW G TV + +G++I NW+ A A+ N ++PL P+ E K P Q++
Sbjct: 29 SAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAVINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWSLECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGLWSGIIICTVFQAVCFLGFIIQ---LNWKKACQQAQVHANLKVNNVPRSGNSALPQDPLHPGCPENLEGILTNDVGKTGEPQSDQQMRQEE 525
BLAST of slc47a-5 vs. Ensembl Human
Match: SLC47A2 (solute carrier family 47 member 2 [Source:HGNC Symbol;Acc:HGNC:26439]) HSP 1 Score: 225.713 bits (574), Expect = 2.612e-65 Identity = 169/562 (30.07%), Postives = 286/562 (50.89%), Query Frame = 3
Query: 123 LIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVT----------------CPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGIT-SSY-------DLIRTKKIIVFENLRLKSKLNK-NHKSIIIKRSVTLFVCLLMLFIGIIGRL 1733
L L GPLF L F+I + +F G L K++L V V+ +++ G SVG GL+ ACDTL SQ++GS +KK G LQ+ + LL P A+ LN H+LLLF QDP + ++ Y+ ++P PV + Y +L++YLQNQ TWP +++ ++GN N A Y + N + SA II+ +F L Y++ K + TW GW+ L +W F LA+P + E +E F+ G++ +V ++ +V+ + TVT PL ++IG+C V++G LGA +AK+ A ++++V +SL +G++ISI++ IFT D+ V VS+++ Y ++ V E++ V G++RG K + + Y++GLP+ +L F+ ++++ GLW+G + +V +W+ LA + A + + Q + + E P P++ + G S GIT ++Y D RT + E L + ++ + K ++I+R L L +G+ R+
Sbjct: 34 LFALSGPLFLFQVLTFMIYIVSTVFCGHLGKVELASVTLAVAFVNVCGVSVGVGLSSACDTLMSQSFGSPNKKHVGVILQRGALVLLLCCLPCWALFLNTQHILLLFRQDPDVSRLTQDYVMIFIPGLPVIFLYNLLAKYLQNQKITWPQVLSGVVGNCVNGVANYALVSVLNLGVRGSAYANIISQFAQTVFLLLYIVLKKLHLETWAGWSSQCLQDWGPFFSLAVPSMLMICVEWWAYEIGSFLMGLLSVVDLSAQAVIYEVATVTYMRHSHRLAYAAHVTRIPLGLSIGVC--VRVGMALGAADTVQAKRSAVSGVLSIVGISLVLGTLISILKNQLGHIFTNDEDVIALVSQVLPVYSVFHVFEAICCVYGGVLRGTGKQAFGAAVNAITYYIIGLPLGILLTFVVRMRIMGLWLGMLACVFLATAAFVAYTARLDWK-LAAEEAKKHSGRQQQQRAESTATRP----GPEKAVLSSVATG---------SSPGITLTTYSRSECHVDFFRTPE----EAHALSAPTSRLSVKQLVIRRGAALGAASATLMVGLTVRI 575
BLAST of slc47a-5 vs. Ensembl Human
Match: SLC47A2 (solute carrier family 47 member 2 [Source:HGNC Symbol;Acc:HGNC:26439]) HSP 1 Score: 213.001 bits (541), Expect = 2.327e-60 Identity = 169/584 (28.94%), Postives = 286/584 (48.97%), Query Frame = 3
Query: 123 LIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQ------------------------------------DKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVT--CPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGIT-SSY-------DLIRTKKIIVFENLRLKSKLNK-NHKSIIIKRSVTLFVCLLMLFIGIIGRL 1733
L L GPLF L F+I + +F G L K++L V V+ +++ G SVG GL+ ACDTL SQ++GS +KK G LQ+ + LL P A+ LN H+LLLF QDP + ++ Y+ ++P PV + Y +L++YLQNQ TWP +++ ++GN N A Y + N + SA II+ +F L Y++ K + TW GW+ L +W F LA+P + E +E F+ G++ +V ++ +V+ + TVT PL ++IG+C V++G LGA +AK+ A ++++V +SL +G++ISI++ IFT D+ V VS+++ Y ++ V E++ V G++RG K + + Y++GLP+ +L F+ ++++ GLW+G + +V +W+ LA + A + + Q + + E P P++ + G S GIT ++Y D RT + E L + ++ + K ++I+R L L +G+ R+
Sbjct: 34 LFALSGPLFLFQVLTFMIYIVSTVFCGHLGKVELASVTLAVAFVNVCGVSVGVGLSSACDTLMSQSFGSPNKKHVGVILQRGALVLLLCCLPCWALFLNTQHILLLFRQDPDVSRLTQDYVMIFIPGLPVIFLYNLLAKYLQNQGWLKGQEEESPFQTPGLSILHPSHSHLSRASFHLFQKITWPQVLSGVVGNCVNGVANYALVSVLNLGVRGSAYANIISQFAQTVFLLLYIVLKKLHLETWAGWSSQCLQDWGPFFSLAVPSMLMICVEWWAYEIGSFLMGLLSVVDLSAQAVIYEVATVTYMIPLGLSIGVC--VRVGMALGAADTVQAKRSAVSGVLSIVGISLVLGTLISILKNQLGHIFTNDEDVIALVSQVLPVYSVFHVFEAICCVYGGVLRGTGKQAFGAAVNAITYYIIGLPLGILLTFVVRMRIMGLWLGMLACVFLATAAFVAYTARLDWK-LAAEEAKKHSGRQQQQRAESTATRP----GPEKAVLSSVATG---------SSPGITLTTYSRSECHVDFFRTPE----EAHALSAPTSRLSVKQLVIRRGAALGAASATLMVGLTVRI 597
BLAST of slc47a-5 vs. Ensembl Human
Match: SLC47A2 (solute carrier family 47 member 2 [Source:HGNC Symbol;Acc:HGNC:26439]) HSP 1 Score: 185.267 bits (469), Expect = 2.429e-52 Identity = 110/301 (36.54%), Postives = 170/301 (56.48%), Query Frame = 3
Query: 123 LIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVT--CPLYVAIGICANVKIGQYLGAGQHERAKKIA 1019
L L GPLF L F+I + +F G L K++L V V+ +++ G SVG GL+ ACDTL SQ++GS +KK G LQ+ + LL P A+ LN H+LLLF QDP + ++ Y+ ++P PV + Y +L++YLQNQ TWP +++ ++GN N A Y + N + SA II+ +F L Y++ K + TW GW+ L +W F LA+P + E +E F+ G++ +V ++ +V+ + TVT PL ++IG+C V++G LGA +AK+ A
Sbjct: 34 LFALSGPLFLFQVLTFMIYIVSTVFCGHLGKVELASVTLAVAFVNVCGVSVGVGLSSACDTLMSQSFGSPNKKHVGVILQRGALVLLLCCLPCWALFLNTQHILLLFRQDPDVSRLTQDYVMIFIPGLPVIFLYNLLAKYLQNQKITWPQVLSGVVGNCVNGVANYALVSVLNLGVRGSAYANIISQFAQTVFLLLYIVLKKLHLETWAGWSSQCLQDWGPFFSLAVPSMLMICVEWWAYEIGSFLMGLLSVVDLSAQAVIYEVATVTYMIPLGLSIGVC--VRVGMALGAADTVQAKRSA 332
BLAST of slc47a-5 vs. Ensembl Zebrafish
Match: slc47a2.1 (solute carrier family 47 member 2.1 [Source:NCBI gene;Acc:560024]) HSP 1 Score: 238.424 bits (607), Expect = 4.157e-70 Identity = 161/554 (29.06%), Postives = 273/554 (49.28%), Query Frame = 3
Query: 81 EKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIG--NTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSS----YDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGII 1724
LL Y L+ L GP+F + + FLI+ +F G L K +L GVA ++VI++ G S+G GL ACDTL SQ +GS + K+ G LQ+ + I LL FP A+L+N + +LL Q P + +S +Y+ ++PA P + Y + RYLQNQ WP ++ GNI N Y+ L+ SA I+ +A+F Y+ +K TW GW+ L W F+RLA+P + E +E F+AG++ + SV+ + T+ + + A+V++G LGAG ERAK A++++V V++S + ++I ++ IFTT++ + +VS+++ Y + + +++ G+ GI+RG K L Y +G P L F + + GLWIG V L +L ++I ++ +W+ +A R E ++E F EN+ K +++ +G+T + L + + I + K +I++R + + + +L+L GI+
Sbjct: 42 RSLLPVNYKTEIVELLKLAGPVFISQLMIFLISFVSTVFCGHLGKTELAGVALAIAVINVTGISIGSGLASACDTLISQTFGSNNLKRVGVILQRGILILLLACFPCWALLINTEPILLAVRQSPNVASLSQLYVKIFMPALPAAFMYQLQGRYLQNQGIIWPQVITGAAGNILNALINYVFLHLLELGVAGSAAANTISQYSLAVFLYVYIRWKNLHKATWDGWSRDCLQEWGAFIRLALPSMLMLCVEWWTYEIGGFLAGLISETELGAQSVVYELATIAYMFPLGFAVAASVRVGNALGAGNTERAKLSAKVALVCGVLVSCVVATLIGCTKDVIAYIFTTEEEIVSRVSQVMIMYGFFHLFDAIAGITGGIVRGAGKQLLGALCNIVGYYFVGFPTGVSLMFALSMGIIGLWIGFFGCVFLQSLF--FIILIYKLDWKKATQEALIRAGVQLTETKDESF---------GLENKGCTEEAA----KESQITEEGLTDANTDLEGLSKGGEGISEAGAKTTVGAVLTTKQLIVRRGLAVLLMVLILAGGIV 580
BLAST of slc47a-5 vs. Ensembl Zebrafish
Match: BX248108.1 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:560089]) HSP 1 Score: 235.728 bits (600), Expect = 4.627e-69 Identity = 161/554 (29.06%), Postives = 269/554 (48.56%), Query Frame = 3
Query: 81 EKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIG--NTVGLSTLMIGYVISVWFFNWETLALDAAHR----LTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGII 1724
+LL Y + L+ L GP+F + + FLI+ +F G L K +L GVA ++VI++ G S+G GL ACDTL SQ +GS + K+ G LQ+ + I LL FP A+L+N + +LL Q P + +S +Y+ ++PA P + Y + YLQNQ WP ++ GNI N Y+ LY + SA I+ +A+ TY+ +K TW GW+ L W F+RLA+P + E +E F+AG++ V + S++ + +V + + A V++G LGAG E+AK A++S+V +++S I +I+ IF+ D+ + +VS+++ Y + ++ + + GI+RG K + Y +G P+ L F + + GLWIG V L +L ++I ++ +W+ +A R LT +YE E +EN + + L+ GIT + L+ +++ K + ++R + F LL+L GI+
Sbjct: 40 RRLLPVNYKEEVMQLLKLAGPVFISQLMIFLISFVSTVFCGHLGKTELAGVALAIAVINVTGISIGSGLASACDTLISQTFGSNNLKRVGVILQRGILILLLACFPCWALLINTEPILLAVRQSPNVASLSQLYVKIFMPALPATFMYQLQGLYLQNQGIIWPQVITGAAGNILNALINYVFLYLLDLGVPGSAAANAISQYSLAVILYTYIRCMGLHKATWDGWSWDCLQEWGSFIRLALPSMLMLCAEWWTYEIGGFLAGLISEVELGAQSIVYELASVMYMFPLGFAVAAGVRVGNALGAGNTEQAKLSAKVSLVCGLLVSSVIAVVIAGTNNIIGYIFSKDEDIVLRVSQVMVMYGFVHLFDATSAITGGIVRGAGKQQIGALCNMVGYYCVGFPIGVSLMFAFNMGIVGLWIGFFTCVFLQSLF--FIILIYRLDWKKATQEALIRAGVQLTEIKYESFG--LENKGCTEEAAQENTEEGQTDTNTDLEGLSKGEGGITDAVALVTVGEVL-------------TAKQLAVRRGLAFFFMLLILTGGIV 576
BLAST of slc47a-5 vs. Ensembl Zebrafish
Match: slc47a3 (solute carrier family 47 member 3 [Source:ZFIN;Acc:ZDB-GENE-130530-755]) HSP 1 Score: 227.639 bits (579), Expect = 1.762e-66 Identity = 143/470 (30.43%), Postives = 242/470 (51.49%), Query Frame = 3
Query: 90 LKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDA------AHRLTRG--QYEDQNEIFEKN 1475
L +Y + ++ L P+F +LI T +F G L K++LDGV V+VI++ G +G+GL+ ACDTL SQ YG+ + ++ G QK++ I LL P A+L+N + +LLL GQ P + +S +Y++ +LP P Y + + +YLQNQ WP ++ ++ NI N Y+ L+ N + SA I+ +A Y+ YK TW GW++ L WD F+ LAIP + E +E +AG++ V + SV+ + + I +V++G +GAG +AK A++SI+ V +++ + ++I + IFT DK + ++V+ ++ Y + + ++ S I++G K L Y +G P+ L F A++ +FGLWIG V + I +++ + NW+ + +A A R T G Q + +NE + N
Sbjct: 24 LPVDYTREFVSMCTLAFPVFLAILFDYLILFTSSVFCGHLGKLELDGVTLAVAVINVLGVGIGFGLSAACDTLISQTYGAGNLQQVGVITQKAIIILLLTCLPCCAILINTESILLLAGQSPEVARVSQLYVNVFLPGLPAVYMFIVQVKYLQNQGIFWPLVITGVVANILNALINYILLFVLNMGVEGSAAANTISQYSLATILFIYIRWKGLYKETWKGWSMDCLQEWDSFIYLAIPSMLMMCGEWWTYEIGGLLAGLISEVELGAQSVMYGLANIAYMFPIGFSIAGSVRVGNAMGAGDVAQAKLSAKVSIMCAVSVAVVLATVIGCSKNVIARIFTNDKDIIQRVATVMVLYTPFHIFDATTAAGSSIVKGLGKQKLGAICNLLGYYGIGCPIGIPLMFAAKMGIFGLWIGLLVSVFLQSIFFIVLLVKLNWKKASEEAQIRAGVAIRRTDGASQEDGENEGCDVN 493
BLAST of slc47a-5 vs. Ensembl Zebrafish
Match: slc47a4 (solute carrier family 47 member 4 [Source:ZFIN;Acc:ZDB-GENE-130530-865]) HSP 1 Score: 214.542 bits (545), Expect = 5.084e-61 Identity = 162/567 (28.57%), Postives = 268/567 (47.27%), Query Frame = 3
Query: 138 GPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFY-PIYFVPESVNGVLS---GIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQG--ITSSYDLI-RTKKIIVFENLRLKSKLNK-----NHKSIIIKRSVTLFVCLLMLFIGIIGRLSI---RPDYNRYKAFVTDSKFNS 1793
GPL FL FL+ MF G+L L G A + I++ + G GL ACDTL SQ +GS + + G LQ+ + I LF P A+L+N LLL GQ+P + I+ +Y+ YLPA P + Y + YLQNQ P + A + N+ N A Y LY ++F SA + ++ K ++ TW GW++ AL +W +++LAIP FE +E F+AG++ V +A V+ + + + + A V++G LGAG+ A +++S+++ V+++ G ++ + IFT+D+ + E VS+L+ Y P+ F NG+L G++ G + + Y +GLP + +L F A LQV G W+G + + L I + ++++ NW+ + +A R + N + T+ N + N YQ+ N G + SS D R V E + K + ++++R +T LL+L +GII L++ + Y + DS F +
Sbjct: 45 GPLLVCRFLNFLLFFVVTMFCGRLGNTVLAGYAMASATINVTAAATGLGLALACDTLVSQTFGSKNLLRVGIILQRGIVILTLFSLPCWALLVNTQPLLLYLGQEPEVARIAQLYVVVYLPAIPAMFLYQLQLSYLQNQGVIKPQMYASAVANVANVIANYFLLYWWDFGVYGSAAANTFAQVFNCFALFCFIRWQKLHEKTWGGWSLEALQDWGSYMKLAIPSTLMTCFEWWIYEVGGFLAGMLSEVDLAAQHVVIMLAYINYMIPLGMQGAACVRVGNALGAGETAAAILTSKVSLISAAVIAIIQGFVLGSTKTVIGYIFTSDESITELVSQLLNIYCPLQF----FNGILCVGMGVLLGTGQQKIAAIANLFGYYCIGLPSSIVLMFTAGLQVAGFWLGLLIAVFLLAIFFTVAIFKLNWKKMTEEAIARTGKSANG------AANGTMTTEFCSNHR----NSFYQVVLNAENGNGYMVVSSQDQDERLNSTAVPEEPNVTGVEEKPPVLLSTTQLVLRRGLTTVAALLILAVGIIIHLTVPLPQVSYGAGANYTVDSNFTT 597
BLAST of slc47a-5 vs. Ensembl Zebrafish
Match: slc47a3 (solute carrier family 47 member 3 [Source:ZFIN;Acc:ZDB-GENE-130530-755]) HSP 1 Score: 191.815 bits (486), Expect = 9.032e-55 Identity = 116/383 (30.29%), Postives = 200/383 (52.22%), Query Frame = 3
Query: 252 IHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWE 1400
I++ G +G+GL+ ACDTL SQ YG+ + ++ G QK++ I LL P A+L+N + +LLL GQ P + +S +Y++ +LP P Y + + +YLQNQ WP ++ ++ NI N Y+ L+ N + SA I+ +A Y+ YK TW GW++ L WD F+ LAIP + E +E +AG++ V + SV+ + + I +V++G +GAG +AK A++SI+ V +++ + ++I + IFT DK + ++V+ ++ Y + + ++ S I++G K L Y +G P+ L F A++ +FGLWIG V + I +++ + NW+
Sbjct: 1 INVLGVGIGFGLSAACDTLISQTYGAGNLQQVGVITQKAIIILLLTCLPCCAILINTESILLLAGQSPEVARVSQLYVNVFLPGLPAVYMFIVQVKYLQNQGIFWPLVITGVVANILNALINYILLFVLNMGVEGSAAANTISQYSLATILFIYIRWKGLYKETWKGWSMDCLQEWDSFIYLAIPSMLMMCGEWWTYEIGGLLAGLISEVELGAQSVMYGLANIAYMFPIGFSIAGSVRVGNAMGAGDVAQAKLSAKVSIMCAVSVAVVLATVIGCSKNVIARIFTNDKDIIQRVATVMVLYTPFHIFDATTVAGSSIVKGLGKQKLGAICNLLGYYGIGCPIGIPLMFAAKMGIFGLWIGLLVSVFLQSIFFIVLLVKLNWK 383
BLAST of slc47a-5 vs. Ensembl Xenopus
Match: tmed6 (transmembrane p24 trafficking protein 6 [Source:Xenbase;Acc:XB-GENE-967876]) HSP 1 Score: 221.09 bits (562), Expect = 7.004e-64 Identity = 160/547 (29.25%), Postives = 265/547 (48.45%), Query Frame = 3
Query: 117 RALIILFGPLFPTTFLQFLINVTPIM----FVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRL-KSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSIR 1742
+ L+ + GPL L +L++V PI+ F G L K +LD A G S++ + G S+G G+ ACDT FSQ YG + K G LQ+ + I L FP A +N ++LLL GQDP + ++ +Y+ T +PA F+ + RYLQNQ WP +V L I N Y+ L+ +AI + ++ + I Y+ K + TWPGWT L +W F LA+P + + + +E I ++G++ +V + S++ Q + + +A+ + + +++G YLGAG+ E+AK+ A++S V ++ +R IFT D + VS ++ ++ + S + GI+RG + ++ G L+ P+A L F A+L V G W G GL+ + I +VI +W NW+ + A R E+ EK P + NG H L ++YD + + I RL K + ++ K ++I+R+ + +L IG+I R +I
Sbjct: 29 KILVSISGPLV----LTYLLDVAPILITTVFCGHLGKSELDAFALGNSIVILAGQSIGLGICSACDTFFSQIYGGKNLKLIGVVLQRGILILSLSCFPCWAFFVNTKNILLLLGQDPSVARLAELYVLTCIPALVGINFFNLEIRYLQNQGIIWPQVVVSFLACIINGILNYVLLFVLKIGVIGAAIAVTVSIVSKVIILFFYIWIRKIHVDTWPGWTKECLKDWGSFFALALPTMIMLSLKWWTFEIAIILSGLINLVELGGQSIMHQIMNLLNKISLALSLASCIRVGTYLGAGETEQAKRSARLSFVISAFPVFLGVGLLIGLRREIASIFTNDSSILFLVSDIMPLCAVFQIVGSACNLFYGILRGIGMQKVGAFVTVGGYLLIVFPMAVPLMFPAKLGVKGFWTGINAGLAVMDIVFVIYLWKANWKLITEKALER------AGLKELKEKGPTALE----------ANGIASSDHFEL------NNYDTMNSAFIGEQHLERLFKHEEKQSMKKLMIRRTFEALAIVSVLGIGLIIRFTIN 549
BLAST of slc47a-5 vs. Ensembl Xenopus
Match: slc47a2 (solute carrier family 47 (multidrug and toxin extrusion), member 2 [Source:NCBI gene;Acc:100125051]) HSP 1 Score: 195.282 bits (495), Expect = 3.661e-54 Identity = 149/557 (26.75%), Postives = 268/557 (48.11%), Query Frame = 3
Query: 90 LKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTS-VGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTR-----GQYEDQNEIFEKNPLLITKPKENEKVNYPN-GPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSI 1739
L E + + L+ L P T FLI + P M L KI+LD + + + + I G VG L+ A D L Q +G ++ K G LQ+ + I LLF FP A+L+N + +LLLF QDP + +++ IY+ +LPA P + Y +L++YLQNQ +P ++ + NIFN Y+ LY SA ++ I I Y++ + Y TW GW+ + W F+RLA+ + E +E +F+AG++G+V +A +++ Q V + + + I ++++G LGAG E+AK+ A + + + +L G +++ +++ IFT+D + VS ++ Y + ++ GI+RG K + Y++GLP+ L F A+L + G W G I +I V+ +W+ + +A R + + +++ ++++ P E V+ N + + S+G + + + ++ +++I+ R + L + L IGI+ RLS+
Sbjct: 41 LPMEVWQEAQKLLALAAPAPYTENQTFLIEICPDMGSEHLGKIRLDFLTWPIDIWPISGQIWVGQVLSMAGDFLVLQTFGGSNLKLVGIILQRGILILLLFCFPCWALLINTESILLLFRQDPEVSKLTQIYVLIFLPALPAAFLYQLLAKYLQNQGIIYPQVLTGFIANIFNALFNYILLYVLGLGVMGSACANTVSQFIQMILLFLYIVWRRLYADTWGGWSQACFEEWGAFIRLAVASMLMLCIEWWAFEISMFLAGVLGMVDLAAQAIIYQVAIVVYLIPLGLCIAGSIRVGHGLGAGNTEQAKRSALVVLCMTELCALLSGILLATLKDVVAYIFTSDPNIVALVSYVLPVYSACLLFDACVAACGGILRGSGKLKVGAISHTVGYYVIGLPLGISLMFAAKLGIIGFWFGILACGIAQSIFLIIFVFKIDWKRASEEAQTRASERVEIPQKIDNKPSVYQEG-----CPTEQGDVDPGNVESIEFSQSSTSSEGTSPT-----------------PAGAAQHTRTLILTRGLALGCAVGTLIIGIVIRLSV 575
BLAST of slc47a-5 vs. Ensembl Xenopus
Match: ccdc85a (coiled-coil domain containing 85A [Source:Xenbase;Acc:XB-GENE-954470]) HSP 1 Score: 155.606 bits (392), Expect = 2.640e-40 Identity = 118/399 (29.57%), Postives = 185/399 (46.37%), Query Frame = 3
Query: 132 LFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXX----XXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQV 1316
+FG FL FLINV +F G L K++LD V +VI + G SVG GL+ ACDTL SQ +G + K G LQ+ + I L FP A+ +N +++LLLF QDP++ S S L + Y F Q + ++ + NI N Y+ L+ SA I + Y+ + + TW GW+I L +W F+ LAIP + E +E M+G++G+V + SV+ Q T + IG+ +V++G LGAG E+AK ++ + + +++ + + IFT D+ V + L+ + F V GI+RG + + + YL+GLP+AA L F + +
Sbjct: 56 IFGAEKLAQFLCFLINVVSAIFCGHLGKVELDAVTLANAVIAVTGLSVGLGLSSACDTLISQIFGGKNLKLIGIILQRGILILFLACFPCWALFINTENILLLFKQDPKVASSSRQCKSVSLNQTKMSYVIF--------QGIVYVQIIVSFVSNIINCIVNYVFLFVLRLGVIGSAWANTIAQFSQCLLIFLYIRVKRLHVNTWGGWSIECLQDWSSFISLAIPSMLMVCIEWWTYEIGNLMSGLLGVVELGAQSVIYQVVTTAYMIPFGIGMATSVRVGNALGAGNIEQAKTSTTVAFLVTGASLPAVIFVDILMLASFKNQFAYIFTNDRWV---FTFLLLYLSFSFC------VAGGILRGTGRQKIGAIINMVGYYLIGLPLAAALMFAVNIGI 437
BLAST of slc47a-5 vs. Ensembl Xenopus
Match: ccdc85a (coiled-coil domain containing 85A [Source:Xenbase;Acc:XB-GENE-954470]) HSP 1 Score: 151.754 bits (382), Expect = 2.851e-39 Identity = 116/394 (29.44%), Postives = 185/394 (46.95%), Query Frame = 3
Query: 159 FLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXX----XXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLW 1328
FL FLINV +F G L K++LD V +VI + G SVG GL+ ACDTL SQ +G + K G LQ+ + I L FP A+ +N +++LLLF QDP++ S S L + Y F Q + ++ + NI N Y+ L+ SA I + Y+ + + TW GW+I L +W F+ LAIP + E +E M+G++G+V + SV+ Q T T + + + +V++G LGAG E+AK ++ + + +++ + + IFT D+ V + L+ + F V GI+RG + + + YL+GLP+AA L F + + G++
Sbjct: 37 FLCFLINVVSAIFCGHLGKVELDAVTLANAVIAVTGLSVGLGLSSACDTLISQIFGGKNLKLIGIILQRGILILFLACFPCWALFINTENILLLFKQDPKVASSSRQCKSVSLNQTKMSYVIF--------QGIVYVQIIVSFVSNIINCIVNYVFLFVLRLGVIGSAWANTIAQFSQCLLIFLYIRVKRLHVNTWGGWSIECLQDWSSFISLAIPSMLMVCIEWWTYEIGNLMSGLLGVVELGAQSVIYQVVT-TAYMVRSASMATSVRVGNALGAGNIEQAKTSTTVAFLVTGASLPAVIFVDILMLASFKNQFAYIFTNDRWV---FTFLLLYLSFSFC------VAGGILRGTGRQKIGAIINMVGYYLIGLPLAAALMFAVNIGIKGIY 412
BLAST of slc47a-5 vs. Ensembl Xenopus
Match: tysnd1 (trypsin domain containing 1 [Source:Xenbase;Acc:XB-GENE-972865]) HSP 1 Score: 104.375 bits (259), Expect = 2.851e-25 Identity = 54/132 (40.91%), Postives = 86/132 (65.15%), Query Frame = 3
Query: 117 RALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPV 512
+ L ++ GP+F + + F++NV +F G L KI+LD V V+VI++ G SVG GL+ ACDTL SQ +G + K+ G LQ+++ I LLF FP A+ +N + +LLL Q+P + + +Y++ ++PA PV
Sbjct: 47 KDLCVIAGPVFLSQIMVFMVNVVSSIFCGHLGKIELDSVTLAVAVINVTGVSVGSGLSSACDTLISQTFGGRNLKRVGTILQRAILIVLLFCFPCWAIFINTEQILLLCKQNPDVARFTQMYVTIFMPALPV 178
BLAST of slc47a-5 vs. Ensembl Mouse
Match: Slc47a1 (solute carrier family 47, member 1 [Source:MGI Symbol;Acc:MGI:1914723]) HSP 1 Score: 240.736 bits (613), Expect = 3.321e-71 Identity = 144/443 (32.51%), Postives = 237/443 (53.50%), Query Frame = 3
Query: 72 GLKEKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWE 1400
GL+ LL +L RAL++L GP F + FLI+ +F G L K++LD V ++VI++ G SVG+GL+ ACDTL SQ YGS + K G LQ+ I LL FP A+ +N + +LLLF QDP + ++ Y+ ++PA P + Y + +YL NQ P ++ + N+ N A Y+ LY + SA+ I+ +AIF Y++ + ++ TW GW+ L +W FLRLAIP + E +E F++GI+G+V + S+ + + + + ANV++G LGAG ++AKK + IS++ + ++T ++ ++ IFTTD+ + V+++I Y + + E + GI+RG + + Y++GLP+ L F A+L V GLW G + + ++ + NW+
Sbjct: 22 GLRCLLLPGFLEEL-RALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMIFIPALPAAFLYTLQVKYLLNQGIVLPQIMTGIAANLVNALANYVFLYHLHLGVMGSALANTISQFALAIFLFLYILWRRLHQATWGGWSWECLQDWASFLRLAIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSITYELAIIVYMIPSGFSVAANVRVGNALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDRDIVALVAQVIPIYAVSHLFEGLACTCGGILRGTGNQKVGAIVNAIGYYVIGLPIGIALMFAAKLGVIGLWSGIIICTTCQTTCFLAFIARLNWK 463
BLAST of slc47a-5 vs. Ensembl Mouse
Match: Slc47a2 (solute carrier family 47, member 2 [Source:MGI Symbol;Acc:MGI:3588190]) HSP 1 Score: 213.386 bits (542), Expect = 6.544e-61 Identity = 133/446 (29.82%), Postives = 226/446 (50.67%), Query Frame = 3
Query: 90 LKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHR 1427
L + + AL+ L GP+F + FLI++ +F G L K++LD V VSV+++ G SVG GL ACDTL SQ++G + K+ G LQ+ + I LL FP A+ LN + LLLL QDP + ++ +Y+ +PA P + + + +RYLQ+Q P ++ + N+ N LY + SA + ++ Y+ + + TW GWT W + RLAIP + E +E F+AG++ + + +V+ + +V + G+ A+V++G LGAG ++A+ ++ V +L +G +++ +++ IFT DK + VS+++ + + + +++ G G++RG K + L Y G P+ L F A+L + GLW G V +S Y+I + NW +A A R
Sbjct: 36 LSPDVRREAAALVALAGPVFLAQLMIFLISIVSSIFCGHLGKVELDAVTLAVSVVNVTGISVGTGLASACDTLMSQSFGGKNLKRVGVILQRGILILLLCCFPCWAIFLNTERLLLLLRQDPDVARLAQVYVMICIPALPAAFLFQLQTRYLQSQGIIMPQVIVGIAANVVNVGMNAFLLYALDLGVVGSAWANTTSQFFLSALLFLYVWWKRIHIHTWGGWTRECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFLAGLVNVTELGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQARCSCTTVLLCAGVCALLVGILLAALKDVVAYIFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRGTGKQKIGAVLNTIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVSFQAFSYLIYILRTNWSRVAEQAQVR 481
BLAST of slc47a-5 vs. Ensembl Mouse
Match: Slc47a2 (solute carrier family 47, member 2 [Source:MGI Symbol;Acc:MGI:3588190]) HSP 1 Score: 210.69 bits (535), Expect = 9.953e-61 Identity = 131/440 (29.77%), Postives = 224/440 (50.91%), Query Frame = 3
Query: 90 LKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLA 1409
L + + AL+ L GP+F + FLI++ +F G L K++LD V VSV+++ G SVG GL ACDTL SQ++G + K+ G LQ+ + I LL FP A+ LN + LLLL QDP + ++ +Y+ +PA P + + + +RYLQ+Q P ++ + N+ N LY + SA + ++ Y+ + + TW GWT W + RLAIP + E +E F+AG++ + + +V+ + +V + G+ A+V++G LGAG ++A+ ++ V +L +G +++ +++ IFT DK + VS+++ + + + +++ G G++RG K + L Y G P+ L F A+L + GLW G V +S Y+I + NW +A
Sbjct: 36 LSPDVRREAAALVALAGPVFLAQLMIFLISIVSSIFCGHLGKVELDAVTLAVSVVNVTGISVGTGLASACDTLMSQSFGGKNLKRVGVILQRGILILLLCCFPCWAIFLNTERLLLLLRQDPDVARLAQVYVMICIPALPAAFLFQLQTRYLQSQGIIMPQVIVGIAANVVNVGMNAFLLYALDLGVVGSAWANTTSQFFLSALLFLYVWWKRIHIHTWGGWTRECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFLAGLVNVTELGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQARCSCTTVLLCAGVCALLVGILLAALKDVVAYIFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRGTGKQKIGAVLNTIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVSFQAFSYLIYILRTNWSRVA 475
BLAST of slc47a-5 vs. Ensembl Mouse
Match: Slc47a1 (solute carrier family 47, member 1 [Source:MGI Symbol;Acc:MGI:1914723]) HSP 1 Score: 149.443 bits (376), Expect = 4.440e-41 Identity = 81/214 (37.85%), Postives = 123/214 (57.48%), Query Frame = 3
Query: 162 LQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAI 803
+ FLI+ +F G L K++LD V ++VI++ G SVG+GL+ ACDTL SQ YGS + K G LQ+ I LL FP A+ +N + +LLLF QDP + ++ Y+ ++PA P + Y + +YL NQ P ++ + N+ N A Y+ LY + SA+ I+ +AIF Y++ + ++ TW GW+ L +W FLRLAI
Sbjct: 1 MMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMIFIPALPAAFLYTLQVKYLLNQGIVLPQIMTGIAANLVNALANYVFLYHLHLGVMGSALANTISQFALAIFLFLYILWRRLHQATWGGWSWECLQDWASFLRLAI 214
BLAST of slc47a-5 vs. Ensembl Mouse
Match: Slc47a1 (solute carrier family 47, member 1 [Source:MGI Symbol;Acc:MGI:1914723]) HSP 1 Score: 114.39 bits (285), Expect = 8.053e-29 Identity = 67/161 (41.61%), Postives = 97/161 (60.25%), Query Frame = 3
Query: 72 GLKEKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQ 554
GL+ LL +L RAL++L GP F + FLI+ +F G L K++LD V ++VI++ G SVG+GL+ ACDTL SQ YGS + K G LQ+ I LL FP A+ +N + +LLLF QDP + ++ Y+ ++PA P + Y + +YL NQ
Sbjct: 22 GLRCLLLPGFLEEL-RALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMIFIPALPAAFLYTLQVKYLLNQ 181
BLAST of slc47a-5 vs. UniProt/SwissProt
Match: sp|Q5RFD2|S47A1_PONAB (Multidrug and toxin extrusion protein 1 OS=Pongo abelii OX=9601 GN=SLC47A1 PE=2 SV=1) HSP 1 Score: 241.506 bits (615), Expect = 1.388e-70 Identity = 147/479 (30.69%), Postives = 253/479 (52.82%), Query Frame = 3
Query: 96 SEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIG---NTVGLSTLMIGYVISVWFFNWETLALDA---AHRLTRGQYEDQNEIFEKNPLLITKPKENEKV 1514
S + + RAL++L GP F + FLI+ +F G L K++LD V ++VI++ G SVG+GL+ ACDTL SQ YGS + K G LQ+S I LL FP A+ LN H+LLLF QDP + ++ Y++ ++PA P + Y + +YL NQ P +V + N+ N A YL L++ + SA+ +I+ +A+ Y++ K ++ TW GW++ L +W FL LA+P + E +E F++GI+G+V + S++ + + + + A+V++G LGAG E+A+K + +S++ V+ ++ ++ +++ IFTTD+ + V++++ Y + + E++ G++RG + + Y++GLP+ L F +L V GLW G TV + +G++I NW+ A A+ N ++PL P+ E +
Sbjct: 29 SAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAVINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALILLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGAIGSALANLISQYTLALLLFFYILGKKLHQATWGGWSLECLQDWASFLHLAVPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATKLGVMGLWSGIIICTVFQAVCFLGFIIQ---LNWKKACQQAQVHANLKVNNVPRSGNSALPQDPLHPGCPENLEGI 504
BLAST of slc47a-5 vs. UniProt/SwissProt
Match: sp|Q8K0H1|S47A1_MOUSE (Multidrug and toxin extrusion protein 1 OS=Mus musculus OX=10090 GN=Slc47a1 PE=1 SV=2) HSP 1 Score: 240.736 bits (613), Expect = 2.323e-70 Identity = 144/443 (32.51%), Postives = 237/443 (53.50%), Query Frame = 3
Query: 72 GLKEKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWE 1400
GL+ LL +L RAL++L GP F + FLI+ +F G L K++LD V ++VI++ G SVG+GL+ ACDTL SQ YGS + K G LQ+ I LL FP A+ +N + +LLLF QDP + ++ Y+ ++PA P + Y + +YL NQ P ++ + N+ N A Y+ LY + SA+ I+ +AIF Y++ + ++ TW GW+ L +W FLRLAIP + E +E F++GI+G+V + S+ + + + + ANV++G LGAG ++AKK + IS++ + ++T ++ ++ IFTTD+ + V+++I Y + + E + GI+RG + + Y++GLP+ L F A+L V GLW G + + ++ + NW+
Sbjct: 22 GLRCLLLPGFLEEL-RALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMIFIPALPAAFLYTLQVKYLLNQGIVLPQIMTGIAANLVNALANYVFLYHLHLGVMGSALANTISQFALAIFLFLYILWRRLHQATWGGWSWECLQDWASFLRLAIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSITYELAIIVYMIPSGFSVAANVRVGNALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDRDIVALVAQVIPIYAVSHLFEGLACTCGGILRGTGNQKVGAIVNAIGYYVIGLPIGIALMFAAKLGVIGLWSGIIICTTCQTTCFLAFIARLNWK 463
BLAST of slc47a-5 vs. UniProt/SwissProt
Match: sp|A1L1P9|S47A1_DANRE (Multidrug and toxin extrusion protein 1 OS=Danio rerio OX=7955 GN=slc47a1 PE=2 SV=1) HSP 1 Score: 238.424 bits (607), Expect = 3.138e-69 Identity = 161/554 (29.06%), Postives = 273/554 (49.28%), Query Frame = 3
Query: 81 EKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIG--NTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSS----YDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGII 1724
LL Y L+ L GP+F + + FLI+ +F G L K +L GVA ++VI++ G S+G GL ACDTL SQ +GS + K+ G LQ+ + I LL FP A+L+N + +LL Q P + +S +Y+ ++PA P + Y + RYLQNQ WP ++ GNI N Y+ L+ SA I+ +A+F Y+ +K TW GW+ L W F+RLA+P + E +E F+AG++ + SV+ + T+ + + A+V++G LGAG ERAK A++++V V++S + ++I ++ IFTT++ + +VS+++ Y + + +++ G+ GI+RG K L Y +G P L F + + GLWIG V L +L ++I ++ +W+ +A R E ++E F EN+ K +++ +G+T + L + + I + K +I++R + + + +L+L GI+
Sbjct: 42 RSLLPVNYKTEIVELLKLAGPVFISQLMIFLISFVSTVFCGHLGKTELAGVALAIAVINVTGISIGSGLASACDTLISQTFGSNNLKRVGVILQRGILILLLACFPCWALLINTEPILLAVRQSPNVASLSQLYVKIFMPALPAAFMYQLQGRYLQNQGIIWPQVITGAAGNILNALINYVFLHLLELGVAGSAAANTISQYSLAVFLYVYIRWKNLHKATWDGWSRDCLQEWGAFIRLALPSMLMLCVEWWTYEIGGFLAGLISETELGAQSVVYELATIAYMFPLGFAVAASVRVGNALGAGNTERAKLSAKVALVCGVLVSCVVATLIGCTKDVIAYIFTTEEEIVSRVSQVMIMYGFFHLFDAIAGITGGIVRGAGKQLLGALCNIVGYYFVGFPTGVSLMFALSMGIIGLWIGFFGCVFLQSLF--FIILIYKLDWKKATQEALIRAGVQLTETKDESF---------GLENKGCTEEAA----KESQITEEGLTDANTDLEGLSKGGEGISEAGAKTTVGAVLTTKQLIVRRGLAVLLMVLILAGGIV 580
BLAST of slc47a-5 vs. UniProt/SwissProt
Match: sp|Q5I0E9|S47A1_RAT (Multidrug and toxin extrusion protein 1 OS=Rattus norvegicus OX=10116 GN=Slc47a1 PE=1 SV=1) HSP 1 Score: 237.269 bits (604), Expect = 5.512e-69 Identity = 136/413 (32.93%), Postives = 226/413 (54.72%), Query Frame = 3
Query: 96 SEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIG 1334
S + + RAL++L GP F + FLI+ +F G L K++LD V ++VI++ G SVG+GL+ ACDTL SQ YGS + K G LQ+ I LL FP A+ +N + +LLLF QDP + ++ Y+ ++PA P + Y + +YL NQ P ++ + N+ N A YL L++ + SA+ I+ +AIF Y++ K + TW GW+ L +W FL+LAIP + E +E F++GI+G+V + S+ + + + + ANV++G LGAG ++AKK + IS++ + ++T ++ ++ IFTTD + V++++ Y + + E++ G++RG + + Y++GLP+ L F+A+L V GLW G
Sbjct: 28 SGFQEELRALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMVFIPALPAAFLYTLQVKYLLNQGIVLPQVITGIAANLVNALANYLFLHQLHLGVMGSALANTISQFALAIFLFLYILWRKLHHATWGGWSWECLQDWASFLQLAIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSITYELAIIVYMIPAGFSVAANVRVGNALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDWDIVALVAQVVPIYAVSHLFEALACTCGGVLRGTGNQKVGAIVNAIGYYVIGLPIGISLMFVAKLGVIGLWSG 440
BLAST of slc47a-5 vs. UniProt/SwissProt
Match: sp|Q96FL8|S47A1_HUMAN (Multidrug and toxin extrusion protein 1 OS=Homo sapiens OX=9606 GN=SLC47A1 PE=1 SV=1) HSP 1 Score: 236.498 bits (602), Expect = 1.170e-68 Identity = 151/500 (30.20%), Postives = 257/500 (51.40%), Query Frame = 3
Query: 96 SEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIG---NTVGLSTLMIGYVISVWFFNWETLALDA---AHRLTRGQYEDQNEIFEKNPLLITKPKENE--------KVNYPNGPYQLKHNR 1553
S + + RAL++L GP F + FLI+ +F G L K++LD V ++VI++ G SVG+GL+ ACDTL SQ YGS + K G LQ+S + LL FP A+ LN H+LLLF QDP + ++ Y++ ++PA P + Y + +YL NQ P +V + N+ N A YL L++ + SA+ +I+ +A+ Y++ K ++ TW GW++ L +W FLRLAIP + E +E F++GI+G+V + S++ + + + + A+V++G LGAG E+A+K + +S++ V+ ++ ++ +++ IFTTD+ + V++++ Y + + E++ G++RG + + Y++GLP+ L F L V GLW G TV + +G++I NW+ A A+ N ++PL P+ E K P Q++
Sbjct: 29 SAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAVINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWSLECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGLWSGIIICTVFQAVCFLGFIIQ---LNWKKACQQAQVHANLKVNNVPRSGNSALPQDPLHPGCPENLEGILTNDVGKTGEPQSDQQMRQEE 525
BLAST of slc47a-5 vs. TrEMBL
Match: A0A0H3YFP0 (Multidrug and toxin extrusion protein OS=Schmidtea mediterranea OX=79327 GN=slc47a-5 PE=2 SV=1) HSP 1 Score: 1129.78 bits (2921), Expect = 0.000e+0 Identity = 582/582 (100.00%), Postives = 582/582 (100.00%), Query Frame = 3
Query: 72 GLKEKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSIRPDYNRYKAFVTDSKFNSTTESMFVK 1817
GLKEKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPVAAVLLNVDHLLLLFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAVVVLSLTIGSIISIIREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSIRPDYNRYKAFVTDSKFNSTTESMFVK
Sbjct: 4 GLKEKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPVAAVLLNVDHLLLLFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAVVVLSLTIGSIISIIREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSIRPDYNRYKAFVTDSKFNSTTESMFVK 585
BLAST of slc47a-5 vs. TrEMBL
Match: A0A267DC31 (Multidrug and toxin extrusion protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig015591g3 PE=3 SV=1) HSP 1 Score: 283.108 bits (723), Expect = 1.672e-83 Identity = 182/593 (30.69%), Postives = 295/593 (49.75%), Query Frame = 3
Query: 81 EKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRL----------------TRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPY-QLKHNRLPSQGITSSYDL---IRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSIRPDYNRYKAFVTDSKFNSTT 1799
+ ++ + + L+ + P+ T FL F+I I+ G+L K++LDG A S+I+ FG S G GL ACDTLFSQ YGSA KK+ G YLQ+S+ I L PF + N++ +L+ GQD + +S+ Y+ + P Y Y I +RYLQNQDK P++ L+ N FN +QYL +Y +NF + S +C +TY +MA L Y++ S+ Y+ TW GW++ L+NW FLRLA+PG+ E I +E F+AGI+G + S+L QT T+ + G+ N+++GQ LGA A+ I ++ ++ + ++ + +++ P ++TTD V +++ + + + V +G +RGC + + F Y +G+ + L L V GLW+G +G+S + Y+ + +W A A R+ R Q ED E LL + + N + P Q +H R PS ++ D IRT I S N + II R T + + IG+I RL+I + ++ + +S +++ T
Sbjct: 9 RRFFNNDLKQEIKKLLTIAWPVVATYFLNFVILSESIIMCGRLGKLELDGAALANSIINGFGLSFGSGLVAACDTLFSQCYGSAYKKRVGLYLQQSILIIGLAPFLIWPFYFNIEPILIALGQDAEVSRMSANYVLYFSPGIFFYYMYLIQARYLQNQDKVIVPMIVALIANAFNILSQYLGIYVWNFGFLCSPVCQCLTYALMAGTMLAYILISRVYRETWNGWSLQCLFNWWQFLRLALPGMGMVCLEIICYEIGTFIAGIIGTSELGAQSILFQTETLAYTCVLGFGVAVNIRVGQNLGANNGPGARLAWIAGICCLLCVASVLCAVFVVGKDFIPGLYTTDPDVLTITAQIFPLLGFFIFLDGLQSVCAGALRGCGRQLTGVIFVFLSYYGLGMTIGLPLALATDLHVIGLWVGLLIGVSLICPAYIAVLARQDWRGQARQAQRRVRAASEKQLRYDTDCEEERQQGEDDQLANETTGLLTDRNHRPYEQNQESSPEKQQQHRRYPSNPAYTTADQLVPIRTPSEIP------SSLSNAATRRIIYIRLATGIAVIGIFSIGLIIRLTINSNNDQPPSPGGNSSWSNVT 595
BLAST of slc47a-5 vs. TrEMBL
Match: A0A267ETL6 (Multidrug and toxin extrusion protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig015591g1 PE=3 SV=1) HSP 1 Score: 283.108 bits (723), Expect = 1.781e-83 Identity = 182/593 (30.69%), Postives = 295/593 (49.75%), Query Frame = 3
Query: 81 EKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRL----------------TRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPY-QLKHNRLPSQGITSSYDL---IRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSIRPDYNRYKAFVTDSKFNSTT 1799
+ ++ + + L+ + P+ T FL F+I I+ G+L K++LDG A S+I+ FG S G GL ACDTLFSQ YGSA KK+ G YLQ+S+ I L PF + N++ +L+ GQD + +S+ Y+ + P Y Y I +RYLQNQDK P++ L+ N FN +QYL +Y +NF + S +C +TY +MA L Y++ S+ Y+ TW GW++ L+NW FLRLA+PG+ E I +E F+AGI+G + S+L QT T+ + G+ N+++GQ LGA A+ I ++ ++ + ++ + +++ P ++TTD V +++ + + + V +G +RGC + + F Y +G+ + L L V GLW+G +G+S + Y+ + +W A A R+ R Q ED E LL + + N + P Q +H R PS ++ D IRT I S N + II R T + + IG+I RL+I + ++ + +S +++ T
Sbjct: 9 RRFFNNDLKQEIKKLLTIAWPVVATYFLNFVILSESIIMCGRLGKLELDGAALANSIINGFGLSFGSGLVAACDTLFSQCYGSAYKKRVGLYLQQSILIIGLAPFLIWPFYFNIEPILIALGQDAEVSRMSANYVLYFSPGIFFYYMYLIQARYLQNQDKVIVPMIVALIANAFNILSQYLGIYVWNFGFLCSPVCQCLTYALMAGTMLAYILISRVYRATWNGWSLQCLFNWWQFLRLALPGMGMVCLEIICYEIGTFIAGIIGTSELGAQSILFQTETLAYTCVLGFGVAVNIRVGQNLGANNGPGARLAWIAGICCLLCVASVLCAVFVVGKDFIPGLYTTDPDVLTITAQIFPLLGFFIFLDGLQSVCAGALRGCGRQLTGVIFVFLSYYGLGMTIGLPLALATDLHVIGLWVGLLIGVSLICPAYIAVLARQDWRGQARQAQRRVRAASEKQLRYDTDCEEERQQGEDDQLANETTGLLTDRNHRPYEQNQESSPEKQQQHRRYPSNPAYTTADQLVPIRTPSEIP------SSLSNAATRRIIYIRLATGIAVIGIFSIGLIIRLTINSNNDQPPSPGGNSSWSNVT 595
BLAST of slc47a-5 vs. TrEMBL
Match: A0A0H3YJN6 (Multidrug and toxin extrusion protein OS=Schmidtea mediterranea OX=79327 GN=slc47a-7 PE=2 SV=1) HSP 1 Score: 280.411 bits (716), Expect = 1.259e-82 Identity = 177/559 (31.66%), Postives = 298/559 (53.31%), Query Frame = 3
Query: 75 LKEKLLKSEYPKLCRALIILFG---PLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLM-IGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSY--DLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRL 1733
L+ + K + ++ + L++L P+ T FLI I+ G + K +LD A SVI++ G +V GL ACDTLFSQ YGS +K G L KS I +FP + A+ +N++ L +L GQD + + ++ Y+ + P +++ IL+RY+QNQ+K PP++ ++ NIFN +QYL +Y F + SAIC IT+L+ L Y++ +K Y+ TW GWT W F +LAIPG A E +E ++G+MG + MA SVL Q T+T + +GI N+++GQYLG+G+ ++A K+ + ++ ++ + S+I ++Y PL+FT D + S+L+ ++ V G +RGC + + + L F YL+G P+ L F+AQL+V GLWIG V L+ + I + + + +W+ A R+ +++ +NE F KN + ++ +++ Y ++ H R S+ + S +++ TK + V E K + I + + F L +L +GI+ +L
Sbjct: 19 LEHEHEKFSFKQMRKELLLLVKIAIPIILTNLCGFLILTESIIIAGHISKYELDACALANSVINVAGIAVATGLCTACDTLFSQMYGSKHRKAIGAMLIKSTMIITIFPILLIALHINMEPLFILMGQDKIVAKDAARYMVIFSPGLLFGFYFLILTRYMQNQNKVLPPMIIGIIVNIFNVVSQYLTVYYFKLGFDFSAICQAITFLLFWALELAYILIAKLYEETWDGWTRDVFLEWGLFTKLAIPGAAMVIMECFCFEIGTLLSGVMGPLEMAAQSVLFQLETITFMISFGVGISVNIRVGQYLGSGKPQQALKVYRYGLLVMMSSFVLTSSLILGFKDYLPLVFTNDGEAQKLSSELLPILVGVQFFDAFGTVTMGALRGCGRQKICVLLIFCSFYLLGQPIGISLAFVAQLKVQGLWIGLLVSLAICVPIAVIYTNFIQDWQHQANLCQKRIAEARHQQENEEF-KNETIESRRNSFQQLEY----FKASHRRSISKSFSVSVPGNIMVTKYVEVTE---------KTYTKAYITKFIIFFSTLCVLIMGILVKL 563
BLAST of slc47a-5 vs. TrEMBL
Match: A0A267DNE9 (Multidrug and toxin extrusion protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026979g1 PE=3 SV=1) HSP 1 Score: 281.952 bits (720), Expect = 1.398e-82 Identity = 172/551 (31.22%), Postives = 280/551 (50.82%), Query Frame = 3
Query: 141 PLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQ-----YEDQNEIFE--KNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKS-------IIIKRSVTLFVCLLMLFIGIIGRLSIRPDY 1751
P+ T FL F+I +M G L K +LDG A S+I+ G S+G GL CDTLFSQ+YGS +K++ G YL +SL I LFPF + AV +N+ +LL GQ P + +++ Y+ + P +FY IL+RYLQNQD+ + P++ + GN+FN +QYLC+Y +NF + SSA+C +T++IM + + Y++ S Y TW GW + +L+NW FL+LA+PG+ + E WE F+AG MG + S+L QT T T + + + I N+++GQ LGA RAK + ++ + I R P +FT D + + + ++ + ++ + +G +RGC + + L Y++GLPV + L+VFGLW+G +G+ Y+ + +W A A R+ + Y+ + E+ + ++P K +E + + S G + ++R+ K H S + + R CL +L IG+IGR++ + Y
Sbjct: 57 PVIVTNFLNFVILSESVMMCGHLTKDELDGAALANSLINALGLSIGVGLCTGCDTLFSQSYGSVNKRRMGTYLLQSLMIIGLFPFLIWAVHINILPILLALGQLPNVSLLAAEYMLWFSPGVIFNFFYLILARYLQNQDRVYAPMLCAVAGNVFNLISQYLCIYVWNFGFVSSAVCQALTFVIMFVLLIGYIVFSHVYVETWNGWDVESLFNWWQFLKLALPGMGMVSLETFCWEVGTFVAGYMGEEELGAQSILFQTETWTFMIALGLSIAVNIRVGQSLGALNGSRAKLVWLAGCCCLLCSATVTTIIFITCRSLLPYMFTNDANIAAIAAGIFPVLGLFQFIDGISCISAGALRGCGRQATGALLVITAYYIIGLPVGIPVALTTSLRVFGLWLGLLIGICITAPTYIFLLCRQDWNRQAELAQERIQVAEERQQVYDTEAELEDSGRSPSTKAKRAASEATALLDDSPGARRLSTASAGGGRRHRRRMPSNPAFVSSIRVVPLRVKPHASDPKKIWRMALTRLAIGLACLGILLIGVIGRVATQNVY 607
BLAST of slc47a-5 vs. Ensembl Cavefish
Match: slc47a2.1 (solute carrier family 47 member 1 [Source:NCBI gene;Acc:103046628]) HSP 1 Score: 236.498 bits (602), Expect = 2.113e-69 Identity = 153/541 (28.28%), Postives = 271/541 (50.09%), Query Frame = 3
Query: 123 LIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIF-------EKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGII 1724
L+ L GP+F + + FLI+ +F G L +L GVA ++VI++ G S+G GL ACDTL SQ +GS + K+ G LQ+ + I LL FP A+L+N + +LL Q PR+ +S +Y+ Y+P+ P + Y + RYLQNQ WP ++ GNI N Y+ L+ + SA I+ +A+F Y+ +K TW GW+ L W F+RLA P + E +E F+AG++G + SV+ + T+ + + A+V++G LGAG E+AK +++++ +++S + ++IS +++ FTT++ + +VS+++A Y + + ++ + GI+RG K + Y +G P+ L F + + GLW G V + + ++I + +W+ +A R Q E ++E + E + TKP + + + K+ + Q K++ V + + K ++I+R + +F+ +L+L GI+
Sbjct: 53 LLKLAGPVFISQLMIFLISFVSTVFCGHLGNTELAGVALAIAVINVTGLSIGSGLASACDTLISQTFGSNNLKRVGVILQRGVLILLLACFPCWAILINTEPILLAVRQSPRVASLSQLYVKIYMPSLPAAFMYQLQGRYLQNQGIIWPQVITGAAGNILNALINYIFLHLLHLGVAGSAAANSISQCSLAVFLYVYIRWKGLHKATWDGWSRDCLQEWGAFIRLAFPSMLMLCVEWWTYEIGGFLAGLIGETELGAQSVIYELATIAYMFPLGFAVAASVRVGNALGAGNTEQAKLSGKVALICGLLVSCGVAALISGLKDVIAYTFTTEQEIIVRVSEVMAMYGFFHLFDATAAITGGIVRGAGKQLVGAMCNIVGFYFVGFPIGVSLMFALSMGIVGLWAGFFVCVFLQSVFFLILICKLDWKKATKEAQVRAGICQTEMKDESYAMENKSCEADEYQGTKPSKED--------HTYKNPDIEGQNKCEETQTAEEKRVAVIGEML-------STKQLVIRRGLAVFLMVLILAGGIV 578
BLAST of slc47a-5 vs. Ensembl Cavefish
Match: slc47a4 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:103045605]) HSP 1 Score: 225.328 bits (573), Expect = 3.520e-65 Identity = 164/559 (29.34%), Postives = 278/559 (49.73%), Query Frame = 3
Query: 138 GPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAF-YPIYFVPESVNGVLS---GIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQ---YEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSI-RPDYNRYKAFVTDSKFN 1790
GPL FL FL+ MF G+L +L G + IH+ T+ GYGLT ACDTL SQ +GS + G LQ+ + I LLF P A+L+N LLLL GQDP + I+ IY+ Y+PA P + Y + YLQNQ P + A ++ NI N A Y+ L+ + SA + I TY+ K + TW GW+ +L +W +++LAIP A F+ +E F+AG++G V +A V+ + + + + A V++G LGAG A +++S++ +L++ +G +I+ + IFT+D+ + E VS+L+ P+ F NG+L GI+ G + + YL+GLP++ +L + A+LQ+ G W+G V + L I +V+ ++ NW+ + +A R G+ + D+ + E N YQ+ +R Q S + + ++ + E + + + ++++R +T +L+L +G + L++ P+ AF+T++ +
Sbjct: 46 GPLLVCRFLNFLLFFVVTMFCGRLGNTELAGYGMASATIHVTATATGYGLTLACDTLVSQTFGSKNLLHVGVILQRGVLILLLFCLPCWALLINTQPLLLLVGQDPEVARIAQIYVVAYIPAVPAMFLYQLQRSYLQNQGVIMPQMYASVVVNIVNVLANYVLLFWLDLGVHGSAAANSFAPIFSCIALFTYIRIKKLHVKTWGGWSSESLQDWGAYMKLAIPSTLMACFDWWIYEIGGFLAGMLGEVDLAAQHVVIMLAYIVYMIPLGLQGAACVRVGNALGAGNTAGAIHTSKVSLILAAILAILLGVVIASTKTVIAFIFTSDESIAELVSELMGICCPLQF----FNGILCVGMGILLGTGQQKIAAIANLLGYYLIGLPLSIILTYPAKLQIAGFWLGLLVAVFLLAIYFVVIIFRLNWKKMTEEAIERAGMGKTVIHSDRRSSHRLSDSFFLAVTNGENGN----SYQIVSSR--DQTEERSPPVAQERQEVGQEEEKSSAASMLSTSQLMVRRGLTTLAAVLILAVGTVVHLTVPLPEV----AFITNNTMD 590
BLAST of slc47a-5 vs. Ensembl Cavefish
Match: slc47a4 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:103046413]) HSP 1 Score: 223.402 bits (568), Expect = 2.120e-64 Identity = 165/561 (29.41%), Postives = 278/561 (49.55%), Query Frame = 3
Query: 138 GPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFY-PIYFVPESVNGVLS---GIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPL-----LITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSI-RPDYNRYKAFVTDSKFN 1790
GPL FL FL+ MF G+L +L G + I++ + G+GL ACDTL SQ +GS + G LQ+ + I LLF P A+L+N LLLL GQDP + I+ IY+ Y+PA P + Y + YLQNQ P + A ++ NI N A Y+ L+ ++ SA + TY+ K + TW GW+ +L +W +++LAIP A FE +E F+AG++G V +A V+ + + + + A V++G LGAG A +++S++ +L++ G +++ + IFT+D+ + E VS+L+ Y P+ F NG+L GI+ G + + YL+GLP++ +L F A+LQV G W+G V + L I +++ ++ NW+ + +A R G+ ++ + L L EN V YQ+ +R Q S + + ++ + E + + + ++I+R +T +L+L +G + L++ P+ AF+T+S +
Sbjct: 46 GPLLVCRFLNFLLFFVVTMFCGRLGNTELAGYGMASATINVTTAATGFGLALACDTLVSQTFGSKNLLHVGVILQRGVLILLLFCLPCWALLINTQPLLLLVGQDPEVARIAQIYVVAYIPAVPAMFLYQLQLSYLQNQGVIIPQMYASVVANIVNALANYVLLFWWDLGVHGSAAANSFAQVFSCFALFTYIRIKKLHVKTWGGWSSESLQDWGAYMKLAIPSTLMACFEWWIYEVGGFLAGMLGEVDLAAQHVVIMLAYINYMIPLGLQGAACVRVGNALGAGNTAGAIHTSKVSLILAAILAILQGIVLASTKTVIAFIFTSDESIAELVSELMGIYCPLQF----FNGILCVGMGILLGTGQQKIAAIANLLGYYLIGLPLSIILTFPAKLQVAGFWLGLLVAVFLLAIYFIVIIFRLNWKKMTEEAIKRAGMGKTVIHSDFRSSHRLSDSFFLAVTNGENGNV------YQIVSSR--DQTEERSPPVAQERQGVRQEEEKSSAAPKLSTSQLMIRRGLTTLAAVLILAVGTVVHLTVPLPEV----AFITNSTMD 590
BLAST of slc47a-5 vs. Ensembl Cavefish
Match: slc47a3 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:103046114]) HSP 1 Score: 216.083 bits (549), Expect = 2.856e-62 Identity = 136/501 (27.15%), Postives = 248/501 (49.50%), Query Frame = 3
Query: 78 KEKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKEN----EKVNYPNGPYQLKHNRLPSQG 1568
K L E K + L L P+ + + +LI+ +F G L +LDGVA ++++++ +VGYGL ACDTL SQ +GS + ++ G +Q+ L I LL FP A+L+N + +LLL Q+P + ++S +Y+ ++PA P + + I S YLQNQ WP ++ + N+ N + Y+ L+ + SA ++ +MAI Y+ +K TW GW++ L WD F LAIPG+ E +E F+AG++ V + S++ + V + + V++G +GAG +AK A++++ V +++ + I+ ++ IF+ D+ + +V+ ++ Y + + ++ I+RG K L Y +G P+ L F A++ +FGLW G + + + ++ + NWE +A Q + EK+ + + E+ E+ YP+ ++ + + + G
Sbjct: 16 KRCLFPEEVKKEVKELSALALPVLLSYIMVYLISFVSTVFCGHLGSTELDGVALAIAILNVSSVAVGYGLASACDTLISQTFGSGNLQRVGVIVQRGLIILLLACFPCWAILINTESILLLVKQNPDVAKLSQMYVKIFMPALPALFVFIIESTYLQNQGIIWPLVITGAIANVLNALSNYVFLFVLDLGVPGSAAANTVSQYLMAIVLFIYIRCRGLHKDTWYGWSMECLQEWDTFFHLAIPGLLMLCAEWWTYELGAFLAGLISPVELGAQSIIYELANVAYMFPIGFSVAGCVRVGNAMGAGDTAQAKLSAKLAMACAVSVAVCLAIIVGFTKDVISYIFSNDEQIRARVATVMVLYAPFHLLDATAAAAGSIVRGLGKQKLGAVGNVFGYYAVGFPIGVSLMFAAKMGIFGLWTGLLICVFFQSVFFITLLSKLNWEKATEEA-------QIRAGVHMNEKDDVDAVQQYEDVGSYEEGTYPDTQSLIQKSSVCTVG 509
BLAST of slc47a-5 vs. Ensembl Cavefish
Match: slc47a3 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:103046114]) HSP 1 Score: 216.468 bits (550), Expect = 3.507e-62 Identity = 129/450 (28.67%), Postives = 229/450 (50.89%), Query Frame = 3
Query: 78 KEKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHR 1427
K L E K + L L P+ + + +LI+ +F G L +LDGVA ++++++ +VGYGL ACDTL SQ +GS + ++ G +Q+ L I LL FP A+L+N + +LLL Q+P + ++S +Y+ ++PA P + + I S YLQNQ WP ++ + N+ N + Y+ L+ + SA ++ +MAI Y+ +K TW GW++ L WD F LAIPG+ E +E F+AG++ V + S++ + V + + V++G +GAG +AK A++++ V +++ + I+ ++ IF+ D+ + +V+ ++ Y + + ++ I+RG K L Y +G P+ L F A++ +FGLW G + + + ++ + NWE +A R
Sbjct: 16 KRCLFPEEVKKEVKELSALALPVLLSYIMVYLISFVSTVFCGHLGSTELDGVALAIAILNVSSVAVGYGLASACDTLISQTFGSGNLQRVGVIVQRGLIILLLACFPCWAILINTESILLLVKQNPDVAKLSQMYVKIFMPALPALFVFIIESTYLQNQGIIWPLVITGAIANVLNALSNYVFLFVLDLGVPGSAAANTVSQYLMAIVLFIYIRCRGLHKDTWYGWSMECLQEWDTFFHLAIPGLLMLCAEWWTYELGAFLAGLISPVELGAQSIIYELANVAYMFPIGFSVAGCVRVGNAMGAGDTAQAKLSAKLAMACAVSVAVCLAIIVGFTKDVISYIFSNDEQIRARVATVMVLYAPFHLLDATAAAAGSIVRGLGKQKLGAVGNVFGYYAVGFPIGVSLMFAAKMGIFGLWTGLLICVFFQSVFFITLLSKLNWEKATEEAQIR 465
BLAST of slc47a-5 vs. Ensembl Yeast
Match: YDR338C_mRNA (Putative protein of unknown function; member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily [Source:SGD;Acc:S000002746]) HSP 1 Score: 97.4413 bits (241), Expect = 1.170e-21 Identity = 107/457 (23.41%), Postives = 200/457 (43.76%), Query Frame = 3
Query: 147 FPTTFLQFLINVTPI---MFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYK--FNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVIS--VWFFNWETL-------------ALDAAHRLTRGQYEDQN 1457
FP F L + P+ + VG L K +L V+ S+ ++ G+ + DTL QAYGS G +LQ+ + SL+ P A + + LL + + ++S ++ + P F+ L R+LQ Q + + + N Y ++ + +AI +++ + +M L Y + K W G++ A +W+D LA GI E++++E + G+ +A S +S + + AIGI + +I ++GA + + A +Q+ + + I+ R I++ D V + +++++ I +S+N V +RG SL + YL G+P+A +L + ++++GLWIG +G + L+IG V + V F +W+ + +D+ LT D+N
Sbjct: 237 FPLIFTFLLEQIFPMVCSLTVGHLGKNELAAVSLA-SMTSNITLAIFEGIATSLDTLCPQAYGSGRFYSVGVHLQRCIAFSLVIYIPFAVMWWYSEPLLSYIIPEKELINLTSRFLRVLILGAPAYIFFENLKRFLQAQGIFDAGIYVLTICAPLNVLVSYTLVWNKYIGVGFIGAAIAVVLNFWLMFFLLLFYALYIDGRK-CWGGFSRKAFTHWNDLGHLAFSGIIMLEAEELSYELLTLFSAYYGVSYLAAQSAVSTMAALLYMIPFAIGISTSTRIANFIGAKRTDFAHISSQVGLSFSFIAGFINCCILVFGRNLIANIYSKDPEVIKLIAQVLPLVGIVQNFDSLNAVAGSCLRGQGMQSLGSIVNLMAYYLFGIPLALILSWFFDMKLYGLWIG--IGSAMLLIGLVEAYYVLFPDWDKIMTYAEILKETEDDEVDSDEYLTDSDDPDEN 689
BLAST of slc47a-5 vs. Ensembl Yeast
Match: ERC1 (Member of the multi-drug and toxin extrusion (MATE) family; the MATE family is part of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily; overproduction confers ethionine resistance and accumulation of S-adenosylmethionine [Source:SGD;Acc:S000001074]) HSP 1 Score: 84.3445 bits (207), Expect = 1.396e-17 Identity = 83/373 (22.25%), Postives = 158/373 (42.36%), Query Frame = 3
Query: 141 PLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPR-ICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLY--KFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWT-----ISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSK---LIAFYPIYFVPESVNGVLSGIMRGCAKH 1226
PL T LQ +++ I V L +L GV G +I G + GL DTL +QAYG+ + G +Q+ I++L P+ V +L R +C +++ Y+ P + R+LQ Q + + + N YL ++ K Y + + ++I Y +M + L Y +T+K + W A NW + LAIPG+ E + +E A +G + S+++ ++ + +I + + ++ ++GA ++ ++S++ V S +I +E +F+T+ V + V L+AF ++ ++ N +G +RG +
Sbjct: 174 PLIFTFILQNSLSLASIFSVSHLGTKELGGVTLGSMTANITGLAAIQGLCTCLDTLCAQAYGAKNYHLVGVLVQRCAVITILAFLPMMYVWFVWSEKILALMIPERELCALAANYLRVTAFGVPGFILFECGKRFLQCQGIFHASTIVLFVCAPLNALMNYLLVWNDKIGIGYLGAPLSVVINYWLMTLGLLIYAMTTKHKERPLKCWNGIIPKEQAFKNWRKMINLAIPGVVMVEAEFLGFEVLTIFASHLGTDALGAQSIVATIASLAYQVPFSISVSTSTRVANFIGASLYDSCMITCRVSLLLSFVCSSMNMFVICRYKEQIASLFSTESAVVKMVVDTLPLLAFMQLF---DAFNASTAGCLRGQGRQ 543
BLAST of slc47a-5 vs. Ensembl Nematostella
Match: EDO46474 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ02]) HSP 1 Score: 164.851 bits (416), Expect = 3.329e-45 Identity = 113/405 (27.90%), Postives = 195/405 (48.15%), Query Frame = 3
Query: 108 KLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFG 1322
K C ++ L P + F ++ ++F G L +++L V+ S I++ G SV GL A +TL SQAYG+ G YLQ+ +CI + + + +H LL G + +I ++ YI LP P + +L RYLQ Q P L ++ YL + + AI + Y + ++ L Y+ K + TW GW+ S L +W F+ LA+PG+ E ++E F+ G + +A H +L Q T++ L + G+ A V +G LG+ Q +RAK + ++S++ + S + + R+Y L FT D+ V + + + V ++ GV++GI+RG + + + L +++ LP+ L F+A L + G
Sbjct: 2 KECIQILKLAWPTVISQVFTFGLSTQSVIFAGHLGELELATVSLASSFINVTGYSVAVGLCTALETLCSQAYGAKKYGMVGTYLQRGICILSVAMLLTYSFWMQTEHFLLGIGVEQQISRMTDKYIMMSLPILPGIFGQTLLQRYLQVQGIMQPVLYIGMVVFCCAIGINYLLVLTLHLGISGIAISFYVNYYLFSVLLLVYIYIRKIHHLTWKGWSFSCLDDWRQFIGLAVPGMMMICVEWWSFEIGSFLLGRIDDSNVAAHGILFQLATISFMLPIGTGLAATVSVGMALGSNQPDRAKLVTKVSLIITIAFSALVAICVVCARKYIVLAFTDDREVINLTIQTLPIVGTFLVFDASQGVMAGIIRGSGRQKIGLVLNVITYFIIALPLGITLTFIAHLDLLG 406
BLAST of slc47a-5 vs. Ensembl Medaka
Match: ENSORLT00000002449.2 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101156384]) HSP 1 Score: 248.44 bits (633), Expect = 5.773e-74 Identity = 152/490 (31.02%), Postives = 257/490 (52.45%), Query Frame = 3
Query: 90 LKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRL-TRGQYEDQNEIFEKN----PLLITKPKEN------EKVNYPN 1526
+ EY + L L GP+ + + F+I+ ++F G L K +L GV+ +++I++ G S+G GL+ CDTL SQ +GS + K+ G LQ+ + I LL FP AVL+N + LLL F Q+P + +S +Y++ ++P+ P + Y + SRYLQNQ WP ++ +GNIFN Y+ LY + SA I+ ++A+ Y+ +K TW GW++ L W F++LAIP + E +E F+AG++G + HSV Q + L + I A+V++G LGAG+ E+AK ++ I+ +++ +G+I+ ++ IFT+D+ + ++ ++ + + G+ GI+RG K + Y+ G+P+ L F A + V GLW G T+ + ++I +W NW+ A +A R + + E + EI + N + +T P + EKVN P
Sbjct: 43 IPEEYRNELKHLFRLAGPVVISQLMVFMISFVSMVFCGHLGKTELAGVSLSIAIINVTGISIGTGLSLTCDTLISQTFGSGNLKRVGVILQRGVLILLLACFPCWAVLINTEPLLLAFKQNPEVSRLSQLYVNIFMPSLPASFMYQLQSRYLQNQGIIWPQVITGAIGNIFNAIINYVLLYPLDLGVAGSAAANAISQFLLAVLLFVYICLKGLHKATWDGWSLDCLQEWGPFVKLAIPSMLMLCLEWWIFEVGGFLAGMIGEAELGAHSVAYQLAVIAYMLPLGISAAASVRVGNALGAGKVEQAKLSCKVPIICGFIVAFMMGTILGSTKDVIGYIFTSDQEILDKAPGVVFVLGFTHFFDCIAGITGGILRGAGKQMVGALCNLVGYYVFGVPIGVSLMFAAHMNVVGLWTGLTICVFMQSSFFLIYLWKLNWKKAAEEAQVRAGVQIKDEKEMEITDCNRIHSQVSVTAPSCDGEDHTYEKVNIPE 532
BLAST of slc47a-5 vs. Ensembl Medaka
Match: slc47a3 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101163594]) HSP 1 Score: 244.588 bits (623), Expect = 7.549e-73 Identity = 159/549 (28.96%), Postives = 275/549 (50.09%), Query Frame = 3
Query: 93 KSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSI 1739
KSE ++ + L GP+ + F ++ +F G L + +L GV+ ++V ++ G S+G GL ACDTL SQ YGS + +K G LQ+++ I LL FP A+L+N +LL F Q+P + ++ +Y+ ++PA P + + +LSRYLQNQ WP ++ L N+ N Y+ L+ SA+ + MA Y++ +K TW GW+ L++W ++RLAIP + E +E F+AG++ V + S++ + V + + NV++G LGAG+ E+ K A++++ ++S+ + +I ++++ +FT D+ + E+VS +I+FY + + ++++ SGI+RG K + Y +G PV L F A+L + GLW G +S + + + NW+ + ++A R G E E T P+ + NY R PS T+ D I T + SK ++++++R + L + L +L GII L I
Sbjct: 36 KSEIKEMSK----LAGPVMIAQLMSFAVSFVSTVFCGHLGRTELAGVSLAIAVSNVTGVSIGVGLASACDTLISQTYGSGNLQKVGVILQRAILILLLACFPCWAILINTRPILLAFRQEPEVASLAQLYVKIFMPALPAAFMFSLLSRYLQNQGIIWPQVITGFLVNLLNALINYIFLFVLKMGVAGSALANTFSQFSMAGILFGYIVCRGLHKATWGGWSKECLHDWGSYIRLAIPSMVMMCVEWWTYEIGGFLAGLISEVELGAQSIVYELANVAYMFPLGFSVAGNVRVGNALGAGETEQGKLSAKLTLFCAGLVSVGMALLIGGLKDHISYVFTYDEKIRERVSDVISFYAPFLLLDAISAACSGIIRGAGKQRVGAICNIVGYYGIGFPVGVPLMFAAKLGIKGLWTGLFTCVSLQCVFLIFYLIRMNWKDVTIEAQIR--AGACETYTE---------TSPEPEDAENY----------RCPSD--TTQLDDIDTLPAV--------SKDELAFRNLVLRRGLALALMLFILAAGIILNLLI 549
BLAST of slc47a-5 vs. Ensembl Medaka
Match: slc47a4 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101165411]) HSP 1 Score: 207.994 bits (528), Expect = 1.124e-58 Identity = 150/554 (27.08%), Postives = 254/554 (45.85%), Query Frame = 3
Query: 138 GPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSI-RPDYNRYKAFVTDSKFNST 1796
GPL L +L+ MF G+L + G + +++ + G+GL ACDTL SQ +G + + G LQ+ + I LLF P +L+N +LL GQDP + I+ +YI+ YLPA P Y + + YLQNQ P + A L NI N Y+ +Y SA ++ + + +F Y+ K + TW GW++ +L W +++LAIP FE +E F AG++ +A + +T + I A ++G LGAG RA ++IS+ ++ G ++ + IFT+D+ + VS LI Y + + V +GI G K + Y +GLP+ L F+A+L+V G WIG + + Y++ ++ NW+ + +A + R Q + + + + LL N N + ++ +P + L ++ +V + R N + +I++R +T+ L +L +GII + P+ KA T+ N+T
Sbjct: 54 GPLLLARILHYLLPFVVTMFCGRLGNNVMAGYGLASATLNVTSAATGFGLALACDTLVSQTFGGRNLLRVGIILQRGIIILLLFCLPCWGLLINAQAVLLCLGQDPVVARIAQLYITAYLPAVPAMYLHHLQVSYLQNQGIIMPQMYAAALANIANVATNYIFIYWLQLGVVGSAAANTLSQVYICVFLFGYIWWKKLHTTTWGGWSVESLQEWGSYMKLAIPSTLMTCFEWWVYEFGGFFAGMLSEEELAAQHAVIMVAFLTYMFPLGIQAAACARVGNALGAGDTARAILSSKISLALAGCFAIVEGIVLGSTKTVIGFIFTSDERIVGLVSHLINAYCFLQFFDGLVCVCTGIFLGTGKQKIPAVAHLIGYYCIGLPLCVTLMFVAKLRVLGFWIGLLICVILQSTFYIVVIFKLNWKKMTEEA---VKRAQKNTRMALVDADALL--DNTGNNASQASNNGHSVE-GYVPVTTENNDGKLEEPERHVVLKQRR----DNLSTSQLILRRGITVIAALGLLSVGIIVHFLVPLPETQFAKANTTEGWINTT 597
BLAST of slc47a-5 vs. Ensembl Medaka
Match: slc47a4 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101165658]) HSP 1 Score: 194.512 bits (493), Expect = 5.338e-54 Identity = 123/430 (28.60%), Postives = 207/430 (48.14%), Query Frame = 3
Query: 138 GPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHR 1427
GPL + L +L+ MF G+L + G + I++ + GYGL ACDTL SQ +G + + G LQ+S+ I LLF P +L+N +LL GQDP + I+ +YI+ +LPA P + + + YLQNQ P + LGN+ N Y+ +Y + SA ++ + + +F Y+ K + TW GW++ +L W +++LA+P FE +E F AG+M +A + +T I A ++G LGAG + A +++++ + + G ++ + IFT D+ + VS+L+ Y + + V +GI G K + F Y +GL ++ L F A+L++ G W+G V + Y++ ++ NWE +A +A R
Sbjct: 34 GPLLLSRILNYLLPFVVTMFCGRLGNEVMAGYGLASATINVTTAATGYGLGLACDTLVSQTFGGKNLLRVGVILQRSIIILLLFCLPCWGLLINAHAILLCLGQDPEVARIAQLYITAFLPAVPAMFLHNLQVSYLQNQGIILPQMYTATLGNVANVVTNYILIYWLDLGVGGSAAANTLSQIYICVFLFLYIWWRKIHVKTWGGWSVESLQEWGSYMKLAVPSTLMKCFEWWVYEFGGFFAGMMSEDELAAQHAVIMVSFITYMFPFGIQAAACARVGNALGAGDNTGALLTSRVALTLAGSICVVEGLVLGSTKTVIGFIFTADERIIHLVSQLMTAYCFLQFFDGLVCVCTGIFLGAGKQKIPAVANFIGYYCLGLSLSITLMFAAKLRILGFWVGLLVCVIFQSTFYIVVIFRLNWEKIADEAVKR 463
BLAST of slc47a-5 vs. Ensembl Medaka
Match: slc47a1 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101170536]) HSP 1 Score: 195.667 bits (496), Expect = 6.542e-54 Identity = 138/435 (31.72%), Postives = 219/435 (50.34%), Query Frame = 3
Query: 132 LFGPLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVT--CPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWF-FNWETLALDAAHR 1427
L GPL + L F I ++ G + ++L G A I++ T+ GYGL ACDTL SQ +G + K+ G LQ+S I L F P A+L+N ++LLLL Q+ + I+ +Y+ +LPA P + + + YLQNQ P + + N+FN A YL + SAI ++ +++ + Y+ K ++ TW GWT + L +W +++LA P E WE F+AG +G +A VL + G+++ PL ++ +C V++G LGAG RA ++++V VLS+ G +I+ + IFT+D + E VS + Y +S+ V SGI+ G + Y +GLPV A L F A L++ GLW+G + S + + + V F +W + L A R
Sbjct: 67 LAGPLLLSRILNFFIPFVVTIYCGHMGNVELAGYALASVTINVTTTATGYGLAVACDTLISQTFGGKNLKRVGVILQRSSLILLFFCLPCWALLINAENLLLLMKQNADVARIAQLYVMMFLPAVPAMFLHHLQVSYLQNQGIILPQMYTAGVANVFNLGANYLLISVLKLGVVGSAIANSLSQIVICLLLFGYIRWRKLHEKTWGGWTTNCLQDWGSYMKLATPSALMICLEWWVWEIGGFLAGALGEKDLAAQHVLVEIGSLSYMFPLGISAAVC--VRVGNALGAGNITRAFVACKLALVLAGVLSVVQGVVIACCKPVAGSIFTSDIDILEIVSNNLTVYIFLQFFDSILCVSSGILVGSGLQKIAALTNLVSYYCIGLPVGAALMFGAHLRILGLWLG-ILTCSCIQAAFFLVVIFKIDWNKITLKAQLR 498
BLAST of slc47a-5 vs. Planmine SMEST
Match: SMESG000077134.1 (SMESG000077134.1) HSP 1 Score: 1046.96 bits (2706), Expect = 0.000e+0 Identity = 540/542 (99.63%), Postives = 540/542 (99.63%), Query Frame = 3
Query: 192 MFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSIRPDYNRYKAFVTDSKFNSTTESMFVK 1817
MFVGQLDKIQLDGVAF VSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPVAAVLLNVDHLLLLFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAVVVLSLTIGSIISIIREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEK NYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSIRPDYNRYKAFVTDSKFNSTTESMFVK
Sbjct: 1 MFVGQLDKIQLDGVAFAVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPVAAVLLNVDHLLLLFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAVVVLSLTIGSIISIIREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKANYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRLSIRPDYNRYKAFVTDSKFNSTTESMFVK 542
BLAST of slc47a-5 vs. Planmine SMEST
Match: SMESG000028980.1 (SMESG000028980.1) HSP 1 Score: 280.411 bits (716), Expect = 3.503e-86 Identity = 177/559 (31.66%), Postives = 298/559 (53.31%), Query Frame = 3
Query: 75 LKEKLLKSEYPKLCRALIILFG---PLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLM-IGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSY--DLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGIIGRL 1733
L+ + K + ++ + L++L P+ T FLI I+ G + K +LD A SVI++ G +V GL ACDTLFSQ YGS +K G L KS I +FP + A+ +N++ L +L GQD + + ++ Y+ + P +++ IL+RY+QNQ+K PP++ ++ NIFN +QYL +Y F + SAIC IT+L+ L Y++ +K Y+ TW GWT W F +LAIPG A E +E ++G+MG + MA SVL Q T+T + +GI N+++GQYLG+G+ ++A K+ + ++ ++ + S+I ++Y PL+FT D + S+L+ ++ V G +RGC + + + L F YL+G P+ L F+AQL+V GLWIG V L+ + I + + + +W+ A R+ +++ +NE F KN + ++ +++ Y ++ H R S+ + S +++ TK + V E K + I + + F L +L +GI+ +L
Sbjct: 19 LEHEHEKFSFKQMRKELLLLVKIAIPIILTNLCGFLILTESIIIAGHISKYELDACALANSVINVAGIAVATGLCTACDTLFSQMYGSKHRKAIGAMLIKSTMIITIFPILLIALHINMEPLFILMGQDKIVAKDAARYMVIFSPGLLFGFYFLILTRYMQNQNKVLPPMIIGIIVNIFNVVSQYLTVYYFKLGFDFSAICQAITFLLFWALELAYILIAKLYEETWDGWTRDVFLEWGLFTKLAIPGAAMVIMECFCFEIGTLLSGVMGPLEMAAQSVLFQLETITFMISFGVGISVNIRVGQYLGSGKPQQALKVYRYGLLVMMSSFVLTSSLILGFKDYLPLVFTNDGEAQKLSSELLPILVGVQFFDAFGTVTMGALRGCGRQKICVLLIFCSFYLLGQPIGISLAFVAQLKVQGLWIGLLVSLAICVPIAVIYTNFIQDWQHQANLCQKRIAEARHQQENEEF-KNETIESRRNSFQQLEY----FKASHRRSISKSFSVSVPGNIMVTKYVEVTE---------KTYTKAYITKFIIFFSTLCVLIMGILVKL 563
BLAST of slc47a-5 vs. Planmine SMEST
Match: SMESG000045551.1 (SMESG000045551.1) HSP 1 Score: 276.174 bits (705), Expect = 1.299e-84 Identity = 167/535 (31.21%), Postives = 283/535 (52.90%), Query Frame = 3
Query: 141 PLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVG--LSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENE------KVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGI 1721
P+ T Q+ +N+ F G+L ++L+GV G+S++ FG V G+ ACDT+FSQ++GS +KK+TG +LQ++ + L P + A +N + +L+L GQDP I ++ ++ + P Y I++RY+Q+Q WP ++A GNIFN +Q L + ++++A C ++ IM + Y+ SKFY+ TWPG+ + A +W + L + G+ + TFE I WEA +FM G++G V +A S++ Q T+T +Y GI +N+++GQ LGA + +AK + V + ++ +G++I I+R PL+FT + V +++ K++ F I + +GV S +RGC + + F Y++ LP + +LGF+ + + G+WIGNT+G +S IG ++ +W+ A A R+ + + ITK E E + + + H R PS +T S ++ K K+N + +SII KR + L L GI
Sbjct: 47 PVLITNVFQYALNIETTSFCGRLTSMELEGVGLGLSLLSAFGWCVCSGMISACDTMFSQSFGSDNKKRTGLFLQRAFLLMNLIPVFLWAWHINAEPILILLGQDPEISRVAGEFLICFTPGLTFMVNYLIMARYMQDQGCLWPAVIAGFCGNIFNICSQLLFVSYLQLGFKAAAFCHASSFGIMVLIEAIYIFKSKFYEATWPGFQLEAFADWGNLFMLGLAGVGHVTFEVIIWEASVFMGGLIGNVELATQSIMLQILTLTFMMYYGAGIASNIRVGQCLGANRPNQAKLAYRAGTVNTAIATIVLGTLIIILRNQIPLVFTNKQDVIDEIQKVMPFMFILMYCDPFSGVFSATLRGCGRQVAGCIIVFVSFYILSLPSSIILGFVFNMSIQGIWIGNTIGSVVSVTTIGILLECQ--DWKHQAHLAQRRI-------------QGNITITKTVETEYLIKSFHLGFEHENKSPSHIRTPSHPVTCSTAIVELP----------KPKINVD-RSIIWKRIIIAGCVFLFLLCGI 555
BLAST of slc47a-5 vs. Planmine SMEST
Match: SMESG000045551.1 (SMESG000045551.1) HSP 1 Score: 275.404 bits (703), Expect = 1.675e-84 Identity = 169/533 (31.71%), Postives = 278/533 (52.16%), Query Frame = 3
Query: 141 PLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENE------KVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVCLLMLFIGI 1721
P+ T Q+ +N+ F G+L ++L+GV G+S++ FG V G+ ACDT+FSQ++GS +KK+TG +LQ++ + L P + A +N + +L+L GQDP I ++ ++ + P Y I++RY+Q+Q WP ++A GNIFN +Q L + ++++A C ++ IM + Y+ SKFY+ TWPG+ + A +W + L + G+ + TFE I WEA +FM G++G V +A S++ Q T+T +Y GI +N+++GQ LGA + +AK + V + ++ +G++I I+R PL+FT + V +++ K++ F I + +GV S +RGC + + F Y++ LP + +LGF+ + + G+WIGNT IG V+SV D H+ Q Q I ITK E E + + + H R PS +T S ++ K K+N + +SII KR + L L GI
Sbjct: 42 PVLITNVFQYALNIETTSFCGRLTSMELEGVGLGLSLLSAFGWCVCSGMISACDTMFSQSFGSDNKKRTGLFLQRAFLLMNLIPVFLWAWHINAEPILILLGQDPEISRVAGEFLICFTPGLTFMVNYLIMARYMQDQGCLWPAVIAGFCGNIFNICSQLLFVSYLQLGFKAAAFCHASSFGIMVLIEAIYIFKSKFYEATWPGFQLEAFADWGNLFMLGLAGVGHVTFEVIIWEASVFMGGLIGNVELATQSIMLQILTLTFMMYYGAGIASNIRVGQCLGANRPNQAKLAYRAGTVNTAIATIVLGTLIIILRNQIPLVFTNKQDVIDEIQKVMPFMFILMYCDPFSGVFSATLRGCGRQVAGCIIVFVSFYILSLPSSIILGFVFNMSIQGIWIGNT-------IGSVVSVTTIGILLECQDWKHQAHLAQRRIQGNI------TITKTVETEYLIKSFHLGFEHENKSPSHIRTPSHPVTCSTAIVELP----------KPKINVD-RSIIWKRIIIAGCVFLFLLCGI 550
BLAST of slc47a-5 vs. Planmine SMEST
Match: SMESG000033095.1 (SMESG000033095.1) HSP 1 Score: 267.7 bits (683), Expect = 2.432e-81 Identity = 169/547 (30.90%), Postives = 290/547 (53.02%), Query Frame = 3
Query: 141 PLFPTTFLQFLINVTPIMFVGQLDKIQLDGVAFGVSVIHIFGTSVGYGLTYACDTLFSQAYGSADKKKTGFYLQKSLCISLLFPFPXXXXXXXXXXXXXXFGQDPRICEISSIYISTYLPAFPVQYFYFILSRYLQNQDKTWPPLVAVLLGNIFNFTAQYLCLYKFNFTYQSSAICMIITYLIMAIFNLTYLITSKFYKPTWPGWTISALYNWDDFLRLAIPGIAYATFEQINWEAEIFMAGIMGIVPMAVHSVLSQTGTVTCPLYVAIGICANVKIGQYLGAGQHERAKKIAQISIVAXXXXXXXXXXXXXXXREYWPLIFTTDKIVNEQVSKLIAFYPIYFVPESVNGVLSGIMRGCAKHSLTMYLAFGCMYLMGLPVAAMLGFLAQLQVFGLWIGNTVGLSTLMIGYVISVWFFNWETLALDAAHRLTRGQYEDQNEIFEKNPLLITKPKENEKVNYPNGPYQLKHNRLPSQGITSSYDLIRTKKIIVFENLRLKSKLNKNHKSIIIKRSVTLFVC-LLMLFIGIIGRLSIRPDYNRYKAFVTD 1778
P+ T Q+ + + F G+L +L+GV +S++ G + G+ ACDT+F+Q++GS DKK+TG +LQ+ L ++ L P + ++ +N++ LL+L GQD +I ++ +++ + P Y +L+RY+Q+Q WPP++A + GN+FN Q L + F ++S+A+C ++ IM + Y+ SKFY TWPG+ + A Y+W L+L + G+ + TFE + WEA +FM G++G V +A S++ Q ++ LY GI +N+++GQ LGA + +AK+ + I + ++ + + I ++R PL+FT K V E + + + + +GV SG +RGCA+ + F Y++ LPV+ + F+ L V G+WIG T G + + + +W+ A A R+ + +N+ EK L+ + +N N P+ H R PS I S + +F+ ++ L KSII KR V +F C +L L GI L + + R F +
Sbjct: 59 PVMITNIFQYSLTIETTSFAGRLTATELEGVGLALSLVGALGWCICTGMVSACDTMFAQSFGSTDKKRTGLFLQRGLLLTNLIPIFLWSLHINLEPLLILCGQDRQISRVAGEFMTCFTPGITFMMNYLLLARYMQDQGCLWPPVIAGICGNVFNICFQLLFVTYLQFGFKSAALCHAFSFGIMTLVEALYIWKSKFYLNTWPGFQLEAFYDWFPMLKLGLAGMGHTTFEVLVWEASVFMGGLLGTVQVATQSIMIQILYISFMLYYGCGIASNIRVGQCLGANRPNQAKQAYRAGIFNTAISTIILATSIILLRYQIPLVFTNKKEVLEMTIDTMPYIFVILYCDPFSGVCSGTLRGCARQLSGCMIIFVSFYMISLPVSIVASFVYDLGVKGIWIGPTCGCIVAVSSIFLLLECQDWKNQAYLAQRRIFSKLADIENDETEK--LIYSLEIDNIAENGPD-----SHIRTPSHPIMCSTE--------IFDTSAPRTNL---EKSIIWKR-VAIFGCAILFLLCGIFIHLFVPLELYRGTNFTLN 586 The following BLAST results are available for this feature:
BLAST of slc47a-5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slc47a-5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of slc47a-5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of slc47a-5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slc47a-5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slc47a-5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slc47a-5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slc47a-5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc47a-5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slc47a-5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of slc47a-5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of slc47a-5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of slc47a-5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slc47a-5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30022038 ID=SMED30022038|Name=slc47a-5|organism=Schmidtea mediterranea sexual|type=transcript|length=1835bpback to top protein sequence of SMED30022038-orf-1 >SMED30022038-orf-1 ID=SMED30022038-orf-1|Name=SMED30022038-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=586bp MIIGLKEKLLKSEYPKLCRALIILFGPLFPTTFLQFLINVTPIMFVGQLDback to top Aliases
The feature 'slc47a-5' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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