G_PROTEIN_RECEP_F1_2 domain-containing protein

Overview
NameG_PROTEIN_RECEP_F1_2 domain-containing protein
Smed IDSMED30022033
Length (bp)1333
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30022033) t-SNE clustered cells

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30022033) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30022033) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30022033) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30022033

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30022033SMESG000043889.1 dd_Smed_v4_16149_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30022033SMESG000043889.1 dd_Smed_v4_16149_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30022033SMESG000043889.1 dd_Smed_v4_16149_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30022033SMESG000043889.1 dd_Smed_v4_16149_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30022033SMESG000043889.1 dd_Smed_v4_16149_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: TRHR (thyrotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:12299])

HSP 1 Score: 68.9366 bits (167), Expect = 4.894e-12
Identity = 75/325 (23.08%), Postives = 153/325 (47.08%), Query Frame = 2 
Query:  131 ICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIR-KTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYI----ITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            + T +++ +IC  GI+ NI+ ++V+ R + M + TN YL+S+++ D+  L++    ++     +  S    +      + L     NA+S     FT+ER + +  P   +  CT ++AKK+I+   +   +      F  ++      D  V+ C  +   ++Y+ I     + M   +F ++P+++  V+   + + +    I +  K  + +  N       N++ N+S           NR  +ST V  + + T +L +VV+ F  L  P     V+V +  +    +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   26 VVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNIT--DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPI-----YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTS-----------NRCFNST-VSSRKQVTKMLAVVVILFALLWMPYR-TLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: TRHR (thyrotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:12299])

HSP 1 Score: 68.9366 bits (167), Expect = 4.894e-12
Identity = 75/325 (23.08%), Postives = 153/325 (47.08%), Query Frame = 2 
Query:  131 ICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIR-KTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYI----ITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            + T +++ +IC  GI+ NI+ ++V+ R + M + TN YL+S+++ D+  L++    ++     +  S    +      + L     NA+S     FT+ER + +  P   +  CT ++AKK+I+   +   +      F  ++      D  V+ C  +   ++Y+ I     + M   +F ++P+++  V+   + + +    I +  K  + +  N       N++ N+S           NR  +ST V  + + T +L +VV+ F  L  P     V+V +  +    +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   26 VVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNIT--DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPI-----YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTS-----------NRCFNST-VSSRKQVTKMLAVVVILFALLWMPYR-TLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: sprr-1 (Sex Peptide Receptor (Drosophila) Related [Source:UniProtKB/TrEMBL;Acc:G5EEU4])

HSP 1 Score: 71.633 bits (174), Expect = 3.662e-13
Identity = 84/346 (24.28%), Postives = 155/346 (44.80%), Query Frame = 2 
Query:  146 ILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLS-----MFCVSLQLYKRVRQSQNLLF---AIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKC----DFQPDNTVMICCIRKTSFYNRIQRHGYFKM----SAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNL--SLHNSQHSTRLNIDA--NSST--------FSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVI--VETRPNRSISKLIFGNFC----NLLLAVSAAMNFILYSFFSQKFR 1081
            ++P I    +  N   ++VL+ + + + TN  LL++++ ++   LS      +  +L  YK   Q+    F    I ++ + L S       WLTV   ++R + +  P  +RK+CT+ ++K+VI   +S A I+ +P++ +   K     D + + T+ +C   +  F  ++    Y+K+      V   +IP V+L +    L+  I  A  +  NL      +  STR       NSS         F Q+D   + N  + +  +    + T +LV+V++ F   + P+A+ + I  +      S     F N      N+L+ VS    F +Y   SQ+FR
Sbjct:   35 MMPFIVTLTVATNSFIVVVLSHKYLRTPTNYVLLAMAVTELLTGLSCLPWFTYYYTLSGYKNDLQTGLPSFWCDMIPYMAAFLPSIFHTMAIWLTVYLAIQRYIYICVPSLVRKFCTIHRSKQVIFFIISVATIMYTPDLMAFHNKSHDVFDSKRNRTMKLCYRHRAPFMLKLGDDIYYKVMFTTQTVAVHLIPSVLLVIFTWKLVGAIRVADRRHANLLSKYSTTTRSTRRKFSELTNSSENENKITRLFKQRDSVSVGNEPRRAHGL---KQNTRMLVVVILLFLITEIPAALIFTIHVLSVSLKFSFVDYQFLNILLIVRNVLIVVSYPFRFAIYCGMSQQFR 377
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: sprr-1 (Sex Peptide Receptor (Drosophila) Related [Source:UniProtKB/TrEMBL;Acc:G5EEU4])

HSP 1 Score: 71.633 bits (174), Expect = 3.662e-13
Identity = 84/346 (24.28%), Postives = 155/346 (44.80%), Query Frame = 2 
Query:  146 ILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLS-----MFCVSLQLYKRVRQSQNLLF---AIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKC----DFQPDNTVMICCIRKTSFYNRIQRHGYFKM----SAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNL--SLHNSQHSTRLNIDA--NSST--------FSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVI--VETRPNRSISKLIFGNFC----NLLLAVSAAMNFILYSFFSQKFR 1081
            ++P I    +  N   ++VL+ + + + TN  LL++++ ++   LS      +  +L  YK   Q+    F    I ++ + L S       WLTV   ++R + +  P  +RK+CT+ ++K+VI   +S A I+ +P++ +   K     D + + T+ +C   +  F  ++    Y+K+      V   +IP V+L +    L+  I  A  +  NL      +  STR       NSS         F Q+D   + N  + +  +    + T +LV+V++ F   + P+A+ + I  +      S     F N      N+L+ VS    F +Y   SQ+FR
Sbjct:   35 MMPFIVTLTVATNSFIVVVLSHKYLRTPTNYVLLAMAVTELLTGLSCLPWFTYYYTLSGYKNDLQTGLPSFWCDMIPYMAAFLPSIFHTMAIWLTVYLAIQRYIYICVPSLVRKFCTIHRSKQVIFFIISVATIMYTPDLMAFHNKSHDVFDSKRNRTMKLCYRHRAPFMLKLGDDIYYKVMFTTQTVAVHLIPSVLLVIFTWKLVGAIRVADRRHANLLSKYSTTTRSTRRKFSELTNSSENENKITRLFKQRDSVSVGNEPRRAHGL---KQNTRMLVVVILLFLITEIPAALIFTIHVLSVSLKFSFVDYQFLNILLIVRNVLIVVSYPFRFAIYCGMSQQFR 377
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-8 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q20686])

HSP 1 Score: 70.8626 bits (172), Expect = 5.469e-13
Identity = 80/345 (23.19%), Postives = 148/345 (42.90%), Query Frame = 2 
Query:   89 NATSVDPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMD---ISYLLSMF-----CVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLF------IMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            N   VD I  +I L+     +P IC  G    ++ I+V TR+ M SS N+YL  +S+ D   +S+   +F     CV LQ +           +  W   P+++ +   + W  V  T++R L V  P   + WCT  +A  +++     + +  +P  F  E+  D         C   +TSF   ++ + Y+K   V F      ++IP  ++ ++N  ++K +  A             +  R ++    +   ++DR                 + T + + +V+TF      +A+N  + ET    S+    +    NLL+ +++A N ++YS F  +FR
Sbjct:   35 NFAEVDYISTYIYLLA----IPTICVLGAGAAVMCIVVFTRKQMRSSLNVYLAGLSVFDLILLSFSALIFSPLQGCV-LQGHGDTAVCHFFWRSTPWTL-PISNIAQCGSVWTCVAVTVDRFLAVNYPLHSKIWCTPRRATTILIAITVFSILFKAPMFF--ELTND--------DCGRLRTSF---LRDNKYYKEYYVTFGYLIALLLIPWTVMIILNVFVVKAVHKA-------------YKIRRSMQGGKNNQEEKDR-----------------RCTLMAIAMVLTFLIFNVVAAVNN-LAETVFEVSLG--FWSPIGNLLICLNSASNIVIYSLFGARFR 327
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-15 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q21413])

HSP 1 Score: 60.077 bits (144), Expect = 1.372e-9
Identity = 87/354 (24.58%), Postives = 147/354 (41.53%), Query Frame = 2 
Query:  119 HIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISST-NIYLLSVSIMDISYLL-SMFCVSLQLYKRVRQSQNLLF------AIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIK-CDFQPDNTVMICCIRKTSF-----YNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLI----------KYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTN---VIDQYKT---TYLLVIVVVTFCCLQTPS-AINYVIVETRPNRSISKL--IFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            H + +    + P +   GI+ N +NI V +++SM + T N + L++S  D+  L+ S+F  S+ +Y     S N  +       IVW F PL       + ++T+  ++ R L V  PF IR+       K VIV  +  AF+  +   F    + C F  +       +  TS      Y  I R+  +    ++   +P  IL  VN  +I          K + T++ KR++ ++      T+  ID  S+    ++    N  L    N   V +  K    T +LV +   F      + A N  I+E    R  + L  +       L+ V+ A   I+Y  F  K+R
Sbjct:   17 HAQFLFRSYLFPFVYLFGIISNSINICVFSQKSMRNHTVNWFFLALSFSDLLTLVASIFVFSVPVY--AENSHNPEYIDLSVQLIVW-FYPLAQIGLTMSVYVTILVSVHRYLGVCHPFLIRRISNSNAVKAVIVAAIVFAFVFNASRWFELHAQPCSFGTEGQTNSSVVYPTSLMMNRMYTLIFRNAAY---TIVMFFLPFAILTYVNLRIIATLKQSYKMRKAMTTSRSKRSDSTVPTDTIVTK--IDGYSAVVPVENGEKGNGILMGGANNGSVKNDKKENGVTVMLVAITTEFLLFNLIAFATN--IIELSSIRFFADLETLLVELSTFLVNVNGASTIIIYLIFGSKYR 360
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-15 (FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:Q21413])

HSP 1 Score: 60.077 bits (144), Expect = 1.372e-9
Identity = 87/354 (24.58%), Postives = 147/354 (41.53%), Query Frame = 2 
Query:  119 HIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISST-NIYLLSVSIMDISYLL-SMFCVSLQLYKRVRQSQNLLF------AIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIK-CDFQPDNTVMICCIRKTSF-----YNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLI----------KYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTN---VIDQYKT---TYLLVIVVVTFCCLQTPS-AINYVIVETRPNRSISKL--IFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            H + +    + P +   GI+ N +NI V +++SM + T N + L++S  D+  L+ S+F  S+ +Y     S N  +       IVW F PL       + ++T+  ++ R L V  PF IR+       K VIV  +  AF+  +   F    + C F  +       +  TS      Y  I R+  +    ++   +P  IL  VN  +I          K + T++ KR++ ++      T+  ID  S+    ++    N  L    N   V +  K    T +LV +   F      + A N  I+E    R  + L  +       L+ V+ A   I+Y  F  K+R
Sbjct:   17 HAQFLFRSYLFPFVYLFGIISNSINICVFSQKSMRNHTVNWFFLALSFSDLLTLVASIFVFSVPVY--AENSHNPEYIDLSVQLIVW-FYPLAQIGLTMSVYVTILVSVHRYLGVCHPFLIRRISNSNAVKAVIVAAIVFAFVFNASRWFELHAQPCSFGTEGQTNSSVVYPTSLMMNRMYTLIFRNAAY---TIVMFFLPFAILTYVNLRIIATLKQSYKMRKAMTTSRSKRSDSTVPTDTIVTK--IDGYSAVVPVENGEKGNGILMGGANNGSVKNDKKENGVTVMLVAITTEFLLFNLIAFATN--IIELSSIRFFADLETLLVELSTFLVNVNGASTIIIYLIFGSKYR 360
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: Proc-R (gene:FBgn0029723 transcript:FBtr0100552)

HSP 1 Score: 81.2629 bits (199), Expect = 3.429e-16
Identity = 56/167 (33.53%), Postives = 90/167 (53.89%), Query Frame = 2 
Query:  104 DPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVI----VLC----LSTAFILTSPEIFSREIKCDFQPDN 580
            D  +  +R +  +I++P +   G++ N ++I VLTR+ M  +TNIYL +++I DI+YL     +SLQ Y   +    L + +   F  L       + ++ VCFT+ER + +  P   + +CT + AKKVI    + C    LSTAF  T   I +R+I   +QP N
Sbjct:   32 DADMAEVRHVVQRILVPCVFVIGLLGNSVSIYVLTRKRMRCTTNIYLTALAITDIAYLTCQLILSLQHYDYPKYHFKLYWQLYGYFVWLCDSFGYISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLLSTLSTAFEHT-ITIGTRQIDDAYQPCN 197

HSP 2 Score: 57.3806 bits (137), Expect = 1.430e-8
Identity = 44/141 (31.21%), Postives = 74/141 (52.48%), Query Frame = 2 
Query:  659 VLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            ++F++ PL++LA  NS+LI  +  +K  R +L+              N+S+  +  R   N+ LK S  V  + + T  L+ VV+ F   Q P AI  ++ +    +  ++++ GN CNLL ++ AA NF LY   S K+R
Sbjct:  362 LVFVVFPLLLLATFNSILILLVHRSKNLRGDLT--------------NASSIRRTKRK-SNSGLKGS--VSQENRVTITLIAVVLMFIVCQLPWAIYLIVNQYMEIQIGTQVVAGNVCNLLASLHAASNFFLYCVLSDKYR 485
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: Proc-R (gene:FBgn0029723 transcript:FBtr0070713)

HSP 1 Score: 81.2629 bits (199), Expect = 3.429e-16
Identity = 56/167 (33.53%), Postives = 90/167 (53.89%), Query Frame = 2 
Query:  104 DPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVI----VLC----LSTAFILTSPEIFSREIKCDFQPDN 580
            D  +  +R +  +I++P +   G++ N ++I VLTR+ M  +TNIYL +++I DI+YL     +SLQ Y   +    L + +   F  L       + ++ VCFT+ER + +  P   + +CT + AKKVI    + C    LSTAF  T   I +R+I   +QP N
Sbjct:   32 DADMAEVRHVVQRILVPCVFVIGLLGNSVSIYVLTRKRMRCTTNIYLTALAITDIAYLTCQLILSLQHYDYPKYHFKLYWQLYGYFVWLCDSFGYISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLLSTLSTAFEHT-ITIGTRQIDDAYQPCN 197

HSP 2 Score: 57.3806 bits (137), Expect = 1.430e-8
Identity = 44/141 (31.21%), Postives = 74/141 (52.48%), Query Frame = 2 
Query:  659 VLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            ++F++ PL++LA  NS+LI  +  +K  R +L+              N+S+  +  R   N+ LK S  V  + + T  L+ VV+ F   Q P AI  ++ +    +  ++++ GN CNLL ++ AA NF LY   S K+R
Sbjct:  362 LVFVVFPLLLLATFNSILILLVHRSKNLRGDLT--------------NASSIRRTKRK-SNSGLKGS--VSQENRVTITLIAVVLMFIVCQLPWAIYLIVNQYMEIQIGTQVVAGNVCNLLASLHAASNFFLYCVLSDKYR 485
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: Proc-R (gene:FBgn0029723 transcript:FBtr0100551)

HSP 1 Score: 81.2629 bits (199), Expect = 3.429e-16
Identity = 56/167 (33.53%), Postives = 90/167 (53.89%), Query Frame = 2 
Query:  104 DPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVI----VLC----LSTAFILTSPEIFSREIKCDFQPDN 580
            D  +  +R +  +I++P +   G++ N ++I VLTR+ M  +TNIYL +++I DI+YL     +SLQ Y   +    L + +   F  L       + ++ VCFT+ER + +  P   + +CT + AKKVI    + C    LSTAF  T   I +R+I   +QP N
Sbjct:   32 DADMAEVRHVVQRILVPCVFVIGLLGNSVSIYVLTRKRMRCTTNIYLTALAITDIAYLTCQLILSLQHYDYPKYHFKLYWQLYGYFVWLCDSFGYISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLLSTLSTAFEHT-ITIGTRQIDDAYQPCN 197

HSP 2 Score: 57.3806 bits (137), Expect = 1.430e-8
Identity = 44/141 (31.21%), Postives = 74/141 (52.48%), Query Frame = 2 
Query:  659 VLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            ++F++ PL++LA  NS+LI  +  +K  R +L+              N+S+  +  R   N+ LK S  V  + + T  L+ VV+ F   Q P AI  ++ +    +  ++++ GN CNLL ++ AA NF LY   S K+R
Sbjct:  362 LVFVVFPLLLLATFNSILILLVHRSKNLRGDLT--------------NASSIRRTKRK-SNSGLKGS--VSQENRVTITLIAVVLMFIVCQLPWAIYLIVNQYMEIQIGTQVVAGNVCNLLASLHAASNFFLYCVLSDKYR 485
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: Proc-R (gene:FBgn0029723 transcript:FBtr0070714)

HSP 1 Score: 81.2629 bits (199), Expect = 3.429e-16
Identity = 56/167 (33.53%), Postives = 90/167 (53.89%), Query Frame = 2 
Query:  104 DPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVI----VLC----LSTAFILTSPEIFSREIKCDFQPDN 580
            D  +  +R +  +I++P +   G++ N ++I VLTR+ M  +TNIYL +++I DI+YL     +SLQ Y   +    L + +   F  L       + ++ VCFT+ER + +  P   + +CT + AKKVI    + C    LSTAF  T   I +R+I   +QP N
Sbjct:   32 DADMAEVRHVVQRILVPCVFVIGLLGNSVSIYVLTRKRMRCTTNIYLTALAITDIAYLTCQLILSLQHYDYPKYHFKLYWQLYGYFVWLCDSFGYISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLLSTLSTAFEHT-ITIGTRQIDDAYQPCN 197

HSP 2 Score: 57.3806 bits (137), Expect = 1.430e-8
Identity = 44/141 (31.21%), Postives = 74/141 (52.48%), Query Frame = 2 
Query:  659 VLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            ++F++ PL++LA  NS+LI  +  +K  R +L+              N+S+  +  R   N+ LK S  V  + + T  L+ VV+ F   Q P AI  ++ +    +  ++++ GN CNLL ++ AA NF LY   S K+R
Sbjct:  362 LVFVVFPLLLLATFNSILILLVHRSKNLRGDLT--------------NASSIRRTKRK-SNSGLKGS--VSQENRVTITLIAVVLMFIVCQLPWAIYLIVNQYMEIQIGTQVVAGNVCNLLASLHAASNFFLYCVLSDKYR 485
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: Proc-R (gene:FBgn0029723 transcript:FBtr0345320)

HSP 1 Score: 81.2629 bits (199), Expect = 3.429e-16
Identity = 56/167 (33.53%), Postives = 90/167 (53.89%), Query Frame = 2 
Query:  104 DPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVI----VLC----LSTAFILTSPEIFSREIKCDFQPDN 580
            D  +  +R +  +I++P +   G++ N ++I VLTR+ M  +TNIYL +++I DI+YL     +SLQ Y   +    L + +   F  L       + ++ VCFT+ER + +  P   + +CT + AKKVI    + C    LSTAF  T   I +R+I   +QP N
Sbjct:   32 DADMAEVRHVVQRILVPCVFVIGLLGNSVSIYVLTRKRMRCTTNIYLTALAITDIAYLTCQLILSLQHYDYPKYHFKLYWQLYGYFVWLCDSFGYISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVAIFCLLSTLSTAFEHT-ITIGTRQIDDAYQPCN 197

HSP 2 Score: 57.3806 bits (137), Expect = 1.430e-8
Identity = 44/141 (31.21%), Postives = 74/141 (52.48%), Query Frame = 2 
Query:  659 VLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            ++F++ PL++LA  NS+LI  +  +K  R +L+              N+S+  +  R   N+ LK S  V  + + T  L+ VV+ F   Q P AI  ++ +    +  ++++ GN CNLL ++ AA NF LY   S K+R
Sbjct:  362 LVFVVFPLLLLATFNSILILLVHRSKNLRGDLT--------------NASSIRRTKRK-SNSGLKGS--VSQENRVTITLIAVVLMFIVCQLPWAIYLIVNQYMEIQIGTQVVAGNVCNLLASLHAASNFFLYCVLSDKYR 485
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: trhra (thyrotropin-releasing hormone receptor a [Source:ZFIN;Acc:ZDB-GENE-100922-18])

HSP 1 Score: 77.0258 bits (188), Expect = 6.225e-15
Identity = 91/354 (25.71%), Postives = 158/354 (44.63%), Query Frame = 2 
Query:   77 SMYCNATSVDPILEHIRLICTKIILPVICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFS-----PLTSFSS---NATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVL--------CLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
              + N T  D  +E+   + + +++ +IC  GI+ N++ I +VLT + M + TN YL+S+++ D+  L +           +     +LF   W++       +T F     NA+S     FT+ER + +  P   +  CT+++AKK+IVL        C+   ++L + E            DN V++ C  K S    +    YF   AV ++ IPL++  V+  L+ + +        N    + + S R                   N  K ST V  + + T +L +VV+ F  L  P     V+V +    +     F  FC L + +++A+N I+Y+  SQKFR A
Sbjct:    4 GTFSNGTWTDNSVEY--KVVSILLVILICGVGIVGNVMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTA---------AGLPNITEILFGGQWVYGYAGCLSITYFQYLGINASSCSITAFTIERYIAICHPIKAQFMCTLSRAKKIIVLVWVLTSLYCVMWFYLLDTREKVY---------DNAVLVTCGYKVS--RELYLPIYFTDYAVFYV-IPLLLATVLYGLIARILF------LNPLPSDPKESRR-------------------NWKKESTTVASRRQVTKMLAVVVILFALLWMPYR-TLVVVNSFLKEAYLDTCFLLFCRLCIYMNSAINPIIYNAMSQKFRAA 308
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: trhra (thyrotropin-releasing hormone receptor a [Source:ZFIN;Acc:ZDB-GENE-100922-18])

HSP 1 Score: 74.3294 bits (181), Expect = 4.816e-14
Identity = 92/354 (25.99%), Postives = 159/354 (44.92%), Query Frame = 2 
Query:   77 SMYCNATSVDPILEHIRLICTKIILPVICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFS-----PLTSFSS---NATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVL--------CLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
              + N T  D  +E+   + + +++ +IC  GI+ N++ I +VLT + M + TN YL+S+++ D+  L +           +     +LF   W++       +T F     NA+S     FT+ER + +  P   +  CT+++AKK+IVL        C+   ++L + E            DN V++ C  K S    +    YF   AV ++ IPL++  V+  L+ + +           L +    +R N    SS       S        ST V  + + T +L +VV+ F  L  P     V+V +    +     F  FC L + +++A+N I+Y+  SQKFR A
Sbjct:    4 GTFSNGTWTDNSVEY--KVVSILLVILICGVGIVGNVMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTA---------AGLPNITEILFGGQWVYGYAGCLSITYFQYLGINASSCSITAFTIERYIAICHPIKAQFMCTLSRAKKIIVLVWVLTSLYCVMWFYLLDTREKVY---------DNAVLVTCGYKVS--RELYLPIYFTDYAVFYV-IPLLLATVLYGLIARILFLN-------PLPSDPKESRRNWKKESSVHGNSRSSSN------STTVASRRQVTKMLAVVVILFALLWMPYR-TLVVVNSFLKEAYLDTCFLLFCRLCIYMNSAINPIIYNAMSQKFRAA 320
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: trhra (thyrotropin-releasing hormone receptor a [Source:ZFIN;Acc:ZDB-GENE-100922-18])

HSP 1 Score: 74.3294 bits (181), Expect = 4.989e-14
Identity = 92/354 (25.99%), Postives = 160/354 (45.20%), Query Frame = 2 
Query:   77 SMYCNATSVDPILEHIRLICTKIILPVICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFS-----PLTSFSS---NATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVL--------CLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
              + N T  D  +E+   + + +++ +IC  GI+ N++ I +VLT + M + TN YL+S+++ D+  L +    ++           +LF   W++       +T F     NA+S     FT+ER + +  P   +  CT+++AKK+IVL        C+   ++L + E            DN V++ C  K S    +    YF   AV ++ IPL++  V+  L+ + +           L +    +R N    SS       S        ST V  + + T +L +VV+ F  L  P     V+V +    +     F  FC L + +++A+N I+Y+  SQKFR A
Sbjct:    8 GTFSNGTWTDNSVEY--KVVSILLVILICGVGIVGNVMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPNIT---------EILFGGQWVYGYAGCLSITYFQYLGINASSCSITAFTIERYIAICHPIKAQFMCTLSRAKKIIVLVWVLTSLYCVMWFYLLDTREKVY---------DNAVLVTCGYKVS--RELYLPIYFTDYAVFYV-IPLLLATVLYGLIARILFLN-------PLPSDPKESRRNWKKESSVHGNSRSSSN------STTVASRRQVTKMLAVVVILFALLWMPYR-TLVVVNSFLKEAYLDTCFLLFCRLCIYMNSAINPIIYNAMSQKFRAA 324
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: trhra (thyrotropin-releasing hormone receptor a [Source:ZFIN;Acc:ZDB-GENE-100922-18])

HSP 1 Score: 74.3294 bits (181), Expect = 5.206e-14
Identity = 92/354 (25.99%), Postives = 160/354 (45.20%), Query Frame = 2 
Query:   77 SMYCNATSVDPILEHIRLICTKIILPVICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFS-----PLTSFSS---NATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVL--------CLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
              + N T  D  +E+   + + +++ +IC  GI+ N++ I +VLT + M + TN YL+S+++ D+  L +    ++           +LF   W++       +T F     NA+S     FT+ER + +  P   +  CT+++AKK+IVL        C+   ++L + E            DN V++ C  K S    +    YF   AV ++ IPL++  V+  L+ + +           L +    +R N    SS       S        ST V  + + T +L +VV+ F  L  P     V+V +    +     F  FC L + +++A+N I+Y+  SQKFR A
Sbjct:    4 GTFSNGTWTDNSVEY--KVVSILLVILICGVGIVGNVMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPNIT---------EILFGGQWVYGYAGCLSITYFQYLGINASSCSITAFTIERYIAICHPIKAQFMCTLSRAKKIIVLVWVLTSLYCVMWFYLLDTREKVY---------DNAVLVTCGYKVS--RELYLPIYFTDYAVFYV-IPLLLATVLYGLIARILFLN-------PLPSDPKESRRNWKKESSVHGNSRSSSN------STTVASRRQVTKMLAVVVILFALLWMPYR-TLVVVNSFLKEAYLDTCFLLFCRLCIYMNSAINPIIYNAMSQKFRAA 320
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: trhrb (thyrotropin-releasing hormone receptor b [Source:ZFIN;Acc:ZDB-GENE-060503-382])

HSP 1 Score: 63.5438 bits (153), Expect = 1.482e-10
Identity = 82/332 (24.70%), Postives = 150/332 (45.18%), Query Frame = 2 
Query:  143 IILPVICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSP-----LTSFSS---NATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKM---SAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLK-----HSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            +I+ +IC  GI+ N++ I +VLT + M + TN YL+S+++ D+  L++    S+          + LF   W+F       +T F     NA+S     FT+ER + +  P   +  CT+++AKK+I+       +      +  +++     D T++ C         ++ R+ Y  +      +F ++PL +  V+  L+ + +         L+   S      N   N   FS+  R    N+LK      ST    + + T +L +VV+ F  L  P     V+V +    +     F  FC   + +++A+N ++Y+  SQKFR A
Sbjct:   27 LIVFLICALGIVGNVMVILVVLTTKHMRTPTNGYLVSLAVADLMVLVAAGLPSIA---------DSLFG-SWVFGHAGCLCITYFQYLGINASSCSITAFTIERYIAICHPIKAQFLCTLSRAKKIIIGVWVFTSLYCVMWFYLSDVQQVLYKDATIITCAY-------KVSRNLYLPIYFFDFGIFFVLPLTLATVLYGLIARILF--------LNPLPSDTKEEKNGHGN---FSKAKR----NKLKSSSRCSSTTAASRRQVTKMLAVVVILFAVLWMPYR-TLVVVNSFLQDAYLDTWFLLFCRTCVYLNSAINPLIYNAMSQKFRAA 325
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: kiaa1324l (KIAA1324-like [Source:Xenbase;Acc:XB-GENE-5954588])

HSP 1 Score: 70.4774 bits (171), Expect = 1.468e-12
Identity = 83/325 (25.54%), Postives = 151/325 (46.46%), Query Frame = 2 
Query:  131 ICTKIILPVICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIR-KTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYI----ITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            + T  ++ +IC  GI+ NI+ + +VL  + M + TN YL+S++I D+  L++    ++   + V  S    +      + L     NA+S     FT+ER L +  P   +  CT+++AKK+IV   +   +      F  ++      D TV+ C  R   SFY+ I     + +   +F  +P+ +  V+  L+ + +    I +  K  + +  N    T  N   NS   S+   + I +R           + T +L +VV+ F  L  P     V+V +  +R   +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   26 VVTVFLVVLICGLGIVGNIMVVLVVLQTKHMRTPTNCYLVSLAIADLIVLVAAGLPNIT--ESVYGSWVYGYIGCLCITYLQYLGINASSCSITAFTVERYLAICHPIKAQFLCTISRAKKIIVFVWAFTSLYCLMWFFLLDLNTTIYKDATVVNCGYRVPRSFYSPI-----YLIDFGIFYAVPMTLATVLYGLIARILFLNPIPSDPKENSKTWKND--VTHQNKAFNSKMSSRCSNNTIASRR----------QVTKMLAVVVILFAFLWMPYR-TLVVVNSFLSRPYLQTWFVLFCRICIYLNSAINPVIYNLMSQKFRAA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: epx (eosinophil peroxidase [Source:Xenbase;Acc:XB-GENE-6039946])

HSP 1 Score: 64.3142 bits (155), Expect = 1.229e-10
Identity = 72/318 (22.64%), Postives = 143/318 (44.97%), Query Frame = 2 
Query:  194 IIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFS-----PLTSFSS---NATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVL--------CLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKM---SAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRL-NIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            ++V T R M + TN YL+S+++ D+  L++    ++        S +L  A  WI+       +T F     NA+S     FT+ER + +  P   +  CTV++AK++I +        C+   F++      S++++C +                  ++ R+ Y  +      +F + PL++  ++  L+ + +  +      +  H    + R     +   T S+ + +  +NRLK    +  + + T +L +VVV F  L  P     V+V +  ++      F  FC + +  ++A+N ++Y+  SQKFR A
Sbjct:   51 LVVFTTRDMRTPTNCYLVSLAVADLMVLVAAGLPNV--------SDSL--AGTWIYGHAGCLGITYFQYLGINASSCSITAFTVERYIAICHPMRAQTVCTVSRAKRIIAIVWIFTSIYCMFWFFLVDIHVNKSQQVECGY------------------KVSRNLYLPIYLADFAIFYVTPLLVATILYGLIGRILFLSP-----IPQHPESTTERWREKSSKEKTESETEGNKPSNRLKTKGALSSRKQVTKMLAVVVVLFALLWMPYR-TLVLVNSFMDKPYLDPWFLLFCRICVYANSAINPVIYNLMSQKFRTA 334
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000016730.1 (thyrotropin-releasing hormone receptor 3 [Source:NCBI gene;Acc:100489565])

HSP 1 Score: 63.5438 bits (153), Expect = 2.447e-10
Identity = 83/348 (23.85%), Postives = 156/348 (44.83%), Query Frame = 2 
Query:   89 NATSVDPILEHIRLICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVL--------CLSTAFILTSPEI-FSR--EIKCDFQPDNTVMICCIRKTSFYNRIQRHGY---FKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            N T +  I   ++++   ++L +IC  GI  NI+ ++V+ R + M++ TN YL+S++I D+  LL+     L     V  S    +      + L     N ++     FT+ER + +      +  CTV++AKK+I          C+   F++   E+ F+   ++ C +                  R+ R+ Y   + +   +F +IPLV+  V+  L+ + +        N    N Q  +R++       ++    S   N+   S+    + + T +L +VV+ F  L  P     V+V +  +     + F  FC L + +++A+N I+Y+  SQKFR A
Sbjct:    3 NQTLMPQIALEVQVVTISLVL-LICGVGIAGNIMVVLVVLRTKHMMTPTNCYLVSLAIADLIVLLA---AGLPNISEVVASWVYGYVGCLCITYLQYLGINISACSITAFTVERYIAICHSIKAQFICTVSRAKKIIAFVWFFTSMYCVMWFFLVDITEVKFADGVQVNCGY------------------RVSRNLYTPIYFLDFTIFYVIPLVLATVLYGLIARILFM------NPLPSNPQDLSRMSSKHYGKPYNSIKLSGKGNKNTASS----RKQVTKMLAVVVILFALLWMPYR-TLVVVNSFMDPPYLNVWFVLFCRLCIYLNSAINPIIYNLMSQKFRAA 317
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000031646.1 (thyrotropin-releasing hormone receptor 3 [Source:NCBI gene;Acc:100489565])

HSP 1 Score: 62.3882 bits (150), Expect = 5.936e-10
Identity = 82/345 (23.77%), Postives = 155/345 (44.93%), Query Frame = 2 
Query:   98 SVDPILEHIRLICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVL--------CLSTAFILTSPEI-FSR--EIKCDFQPDNTVMICCIRKTSFYNRIQRHGY---FKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            S+  I   ++++   ++L +IC  GI  NI+ ++V+ R + M++ TN YL+S++I D+  LL+     L     V  S    +      + L     N ++     FT+ER + +      +  CTV++AKK+I          C+   F++   E+ F+   ++ C +                  R+ R+ Y   + +   +F +IPLV+  V+  L+ + +        N    N Q  +R++       ++    S   N+   S+    + + T +L +VV+ F  L  P     V+V +  +     + F  FC L + +++A+N I+Y+  SQKFR A
Sbjct:   24 SMPQIALEVQVVTISLVL-LICGVGIAGNIMVVLVVLRTKHMMTPTNCYLVSLAIADLIVLLA---AGLPNISEVVASWVYGYVGCLCITYLQYLGINISACSITAFTVERYIAICHSIKAQFICTVSRAKKIIAFVWFFTSMYCVMWFFLVDITEVKFADGVQVNCGY------------------RVSRNLYTPIYFLDFTIFYVIPLVLATVLYGLIARILFM------NPLPSNPQDLSRMSSKHYGKPYNSIKLSGKGNKNTASS----RKQVTKMLAVVVILFALLWMPYR-TLVVVNSFMDPPYLNVWFVLFCRLCIYLNSAINPIIYNLMSQKFRAA 335
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000016751.1 (thyrotropin-releasing hormone receptor 3 [Source:NCBI gene;Acc:100489565])

HSP 1 Score: 62.003 bits (149), Expect = 6.825e-10
Identity = 82/345 (23.77%), Postives = 155/345 (44.93%), Query Frame = 2 
Query:   98 SVDPILEHIRLICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVL--------CLSTAFILTSPEI-FSR--EIKCDFQPDNTVMICCIRKTSFYNRIQRHGY---FKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            S+  I   ++++   ++L +IC  GI  NI+ ++V+ R + M++ TN YL+S++I D+  LL+     L     V  S    +      + L     N ++     FT+ER + +      +  CTV++AKK+I          C+   F++   E+ F+   ++ C +                  R+ R+ Y   + +   +F +IPLV+  V+  L+ + +        N    N Q  +R++       ++    S   N+   S+    + + T +L +VV+ F  L  P     V+V +  +     + F  FC L + +++A+N I+Y+  SQKFR A
Sbjct:   24 SMPQIALEVQVVTISLVL-LICGVGIAGNIMVVLVVLRTKHMMTPTNCYLVSLAIADLIVLLA---AGLPNISEVVASWVYGYVGCLCITYLQYLGINISACSITAFTVERYIAICHSIKAQFICTVSRAKKIIAFVWFFTSMYCVMWFFLVDITEVKFADGVQVNCGY------------------RVSRNLYTPIYFLDFTIFYVIPLVLATVLYGLIARILFM------NPLPSNPQDLSRMSSKHYGKPYNSIKLSGKGNKNTASS----RKQVTKMLAVVVILFALLWMPYR-TLVVVNSFMDPPYLNVWFVLFCRLCIYLNSAINPIIYNLMSQKFRAA 335
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Trhr (thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824])

HSP 1 Score: 66.2402 bits (160), Expect = 2.500e-11
Identity = 83/345 (24.06%), Postives = 164/345 (47.54%), Query Frame = 2 
Query:   89 NATSVDP----ILEHIRLICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTS--FYNRIQRHGYFKMSAVLFIMIPLVILAVVNS-----LLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            N T + P     LE+   + T +++ +IC  GI+ NI+ ++V+ R + M + TN YL+S+++ D+  L++    ++     +  S    +      + L     NA+S     FT+ER + +  P   +  CT ++AKK+I+   +   I      F  ++       N V++ C  K S  +Y+ I     + M   +F ++P+++  V+       L +  I +   + + +  ++S H  + N++ N++           NR  +ST V  + + T +L +VV+ F  L  P     V+V +  +    +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   10 NQTELQPQAAVALEY--QVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNIT--DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNIS-TYKNAVVVSCGYKISRNYYSPI-----YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNK-NLNLNAT-----------NRCFNST-VSSRKQVTKMLAVVVILFALLWMPYR-TLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Trhr (thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824])

HSP 1 Score: 66.2402 bits (160), Expect = 2.500e-11
Identity = 83/345 (24.06%), Postives = 164/345 (47.54%), Query Frame = 2 
Query:   89 NATSVDP----ILEHIRLICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTS--FYNRIQRHGYFKMSAVLFIMIPLVILAVVNS-----LLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            N T + P     LE+   + T +++ +IC  GI+ NI+ ++V+ R + M + TN YL+S+++ D+  L++    ++     +  S    +      + L     NA+S     FT+ER + +  P   +  CT ++AKK+I+   +   I      F  ++       N V++ C  K S  +Y+ I     + M   +F ++P+++  V+       L +  I +   + + +  ++S H  + N++ N++           NR  +ST V  + + T +L +VV+ F  L  P     V+V +  +    +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   10 NQTELQPQAAVALEY--QVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNIT--DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNIS-TYKNAVVVSCGYKISRNYYSPI-----YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNK-NLNLNAT-----------NRCFNST-VSSRKQVTKMLAVVVILFALLWMPYR-TLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Trhr (thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824])

HSP 1 Score: 66.2402 bits (160), Expect = 2.500e-11
Identity = 83/345 (24.06%), Postives = 164/345 (47.54%), Query Frame = 2 
Query:   89 NATSVDP----ILEHIRLICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTS--FYNRIQRHGYFKMSAVLFIMIPLVILAVVNS-----LLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            N T + P     LE+   + T +++ +IC  GI+ NI+ ++V+ R + M + TN YL+S+++ D+  L++    ++     +  S    +      + L     NA+S     FT+ER + +  P   +  CT ++AKK+I+   +   I      F  ++       N V++ C  K S  +Y+ I     + M   +F ++P+++  V+       L +  I +   + + +  ++S H  + N++ N++           NR  +ST V  + + T +L +VV+ F  L  P     V+V +  +    +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   10 NQTELQPQAAVALEY--QVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNIT--DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNIS-TYKNAVVVSCGYKISRNYYSPI-----YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNK-NLNLNAT-----------NRCFNST-VSSRKQVTKMLAVVVILFALLWMPYR-TLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|O93603|TRFR_CHICK (Thyrotropin-releasing hormone receptor OS=Gallus gallus OX=9031 GN=TRHR PE=2 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 1.984e-14
Identity = 80/326 (24.54%), Postives = 162/326 (49.69%), Query Frame = 2 
Query:  131 ICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFC--VSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKT-SFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKH---STNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            + T +++ +IC  GI+ NI+ ++V+ R + M + TN YL+S+++ D+  L++     ++  LYK           I +    L     NA+S+    FT+ER + +  P   +  CT ++AKK+I+   S A +      F  ++      D TV+ C  + + S+Y+ I     + M   +F ++P+V+  V+  L+ +           L L+      + N +   +  +QQ+++ +N+++ +   ++ +  + + T +L +VVV F  L  P     V+V +  +    +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   28 VVTILLVLLICGLGIVGNIMVVLVVLRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITESLYKSWVYGYVGCLCITY----LQYLGINASSFSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWSFASVYCMLWFFLLDLNIAVYKDTTVVSCGYKVSRSYYSPI-----YMMDFGIFYVLPMVLATVLYGLIARI----------LFLNPIPSDPKENSNTWKNDMAQQNKT-VNSKMTNKSFNSTIASRRQVTKMLAVVVVLFAFLWMPYR-TLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAA 332
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|O46639|TRFR_BOVIN (Thyrotropin-releasing hormone receptor OS=Bos taurus OX=9913 GN=TRHR PE=3 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 1.028e-11
Identity = 77/326 (23.62%), Postives = 157/326 (48.16%), Query Frame = 2 
Query:  131 ICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIR-KTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNS-----LLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            + T +++ +IC  GI+ NI+ ++V+ R + M + TN YL+S+++ D+  L++    ++     +  S    +      + L     NA+S     FT+ER + +  P   +  CT ++AKK+I+   +   I      F  ++      D  V+ C  +   ++Y+ I     + M   +F ++P+++  V+       L +  I +   + +N+  ++S H  + N+++ +S           NR  +ST V  + + T +L +VV+ F  L  P     V+V +  +    +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   26 VVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNIT--DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVVSCGYKISRNYYSPI-----YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSNMWKNDSTHQNK-NLNSKTS-----------NRYFNST-VSSRKQVTKMLAVVVILFALLWMPYR-TLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q28596|TRFR_SHEEP (Thyrotropin-releasing hormone receptor OS=Ovis aries OX=9940 GN=TRHR PE=2 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 1.334e-11
Identity = 79/325 (24.31%), Postives = 155/325 (47.69%), Query Frame = 2 
Query:  131 ICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIR-KTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYI----ITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            + T +++ +IC  GI+ NI+ ++V+ R + M + TN YL+S+++ D+  L++    ++     +  S    +      + L     NA+S     FT+ER + +  P   +  CT ++AKK+I+   +   I      F  ++      D  V+ C  +   ++Y+ I     + M   +F ++P+++  V+   + + +    I +  K  + +  N   ST  N + NS T         +NR  +ST V  + + T +L +VV+ F  L  P     V+V +  +    +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   26 VVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNIT--DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVVSCGYKISRNYYSPI-----YLMDFGVFYVVPMILATVLYGFIARILFLSPIPSDPKENSNTWKND--STHQNKNLNSKT---------SNRYFNST-VSSRKQVTKMLAVVVILFALLWMPYR-TLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|P34981|TRFR_HUMAN (Thyrotropin-releasing hormone receptor OS=Homo sapiens OX=9606 GN=TRHR PE=1 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 2.350e-11
Identity = 75/325 (23.08%), Postives = 153/325 (47.08%), Query Frame = 2 
Query:  131 ICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIR-KTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYI----ITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            + T +++ +IC  GI+ NI+ ++V+ R + M + TN YL+S+++ D+  L++    ++     +  S    +      + L     NA+S     FT+ER + +  P   +  CT ++AKK+I+   +   +      F  ++      D  V+ C  +   ++Y+ I     + M   +F ++P+++  V+   + + +    I +  K  + +  N       N++ N+S           NR  +ST V  + + T +L +VV+ F  L  P     V+V +  +    +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   26 VVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNIT--DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPI-----YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTS-----------NRCFNST-VSSRKQVTKMLAVVVILFALLWMPYR-TLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|P21761|TRFR_MOUSE (Thyrotropin-releasing hormone receptor OS=Mus musculus OX=10090 GN=Trhr PE=2 SV=1)

HSP 1 Score: 66.2402 bits (160), Expect = 1.749e-10
Identity = 83/345 (24.06%), Postives = 164/345 (47.54%), Query Frame = 2 
Query:   89 NATSVDP----ILEHIRLICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTS--FYNRIQRHGYFKMSAVLFIMIPLVILAVVNS-----LLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            N T + P     LE+   + T +++ +IC  GI+ NI+ ++V+ R + M + TN YL+S+++ D+  L++    ++     +  S    +      + L     NA+S     FT+ER + +  P   +  CT ++AKK+I+   +   I      F  ++       N V++ C  K S  +Y+ I     + M   +F ++P+++  V+       L +  I +   + + +  ++S H  + N++ N++           NR  +ST V  + + T +L +VV+ F  L  P     V+V +  +    +  F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   10 NQTELQPQAAVALEY--QVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNIT--DSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNIS-TYKNAVVVSCGYKISRNYYSPI-----YLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNK-NLNLNAT-----------NRCFNST-VSSRKQVTKMLAVVVILFALLWMPYR-TLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A5J4P3C7 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0011841 PE=4 SV=1)

HSP 1 Score: 185.267 bits (469), Expect = 1.848e-50
Identity = 114/347 (32.85%), Postives = 198/347 (57.06%), Query Frame = 2 
Query:  101 VDPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQP---DNTVMICCIR--KTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLH--NSQHSTRLNIDANSS---TFSQQDRSLINNRLKHSTNVI-DQYKTTYLLVIVVVTFCCLQTPSAI---------NYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            ++ I + +RL C KI+ P  C+ G++ N LN++VLTR  M SSTN+YL +V++ DI YLL  F  SL  Y  +R+++  +++I +I      F SN  +WLTVCFT+ER + V  P   R++CT  +A+ V+ +    +  +T P+   R +  +  P   ++++++   R  ++S+Y  +   GY  ++ VLF++IP+V+L + NSLL++ ++ A   R  L  H   S+ + +  +D  S    +FSQ  ++++         +  +Q + T +L+ +V+ F  LQ PS +           ++V+T  N+    +++ N  N+LL V+AAMNF+ YS FS KFR
Sbjct:    6 LNEIHKVLRLTCGKILTPCFCFVGLIANTLNVVVLTRAWMSSSTNVYLTAVAVCDIFYLLFCFLFSLYAYDTIREAKFYIYSISFILGTANLF-SNTNTWLTVCFTLERYIAVSSPILGRRFCTQQRARYVVAVVFLLSLFITFPDYLKRTVVVEQSPHPTNSSILVPLYRLVESSYYKYLVLIGYNYINQVLFVLIPMVLLIIFNSLLVRSVLQANKGRRGLVRHTNGSRSNIQTAVDLTSGITQSFSQSGKAIVLQPTHQRRPIFGEQQRITIMLISIVMAFVLLQLPSTVPNIADSLWKAGILVQTEINKKY-MMLYSNVSNVLLIVNAAMNFVFYSLFSAKFR 350
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A1S3IC78 (FMRFamide receptor OS=Lingula unguis OX=7574 GN=LOC106162945 PE=4 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 1.505e-40
Identity = 107/331 (32.33%), Postives = 176/331 (53.17%), Query Frame = 2 
Query:  104 DPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKR--VRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVI---VETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            DP L  +R I  +I +P++   G++ N+LNIIVL+R+ M SSTN YLL+++  D  YL+    ++++ ++   +   +    A+ WI  PLT   SNA+ WLTV FT+ER + +  P   ++WCT  +A+ +I+       I+T PE +  E      P        ++ T  Y+      Y   + +  +++PL +L + N+LLI+ +  A   R  LS   SQ   +                      +HS    +Q + T +L+ VV+ F   Q PSAI+Y++   +E  P   +++ IFGNF NLL+ ++AA+NF+LY+FFS +FR
Sbjct:   54 DPTLLMVRFIVCEIFVPIVVTFGVIGNVLNIIVLSRKWMKSSTNYYLLALASCDSLYLILALTITMKNWQELPIADMRTYWRAMAWI-RPLTDIFSNASVWLTVTFTVERYIGIRHPMKGKRWCTPQRARWIILCVFIFVTIITLPEFWEYEK----NPTRIYQGTALQNTDGYSVY----YIWFNQISCVILPLSLLIIFNTLLIRCVWKANKMRKELS-GGSQREEK----------------------QHS----EQQRITVMLITVVIVFLVCQLPSAISYLVSSFIENTPRVILNRKIFGNFSNLLVEINAALNFVLYNFFSARFR 348
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A087TQJ1 (FMRFamide receptor (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_03111 PE=4 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 4.422e-38
Identity = 108/345 (31.30%), Postives = 169/345 (48.99%), Query Frame = 2 
Query:   89 NATSVDPILEHI----RLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSP----LTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQP-DNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAI-----NYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            +A   DP LE      R    K+++P+I   G++ N + I ++T+R M SSTN YL +++I D+SYL+  F +S Q Y  +  SQ   F   W F P    +T  SSN++ W+TV FT+ER + V  P   + +CT ++AKK+IV+   + F++T P  F   I     P  N   I         N + +  Y+   +V+FIMIP ++LAV N+ LIK + ++K +R  ++                             R +       + K T +L+ VV+ F   Q P+A+      +  V    N  +     GN  N L+A++AA NF+LY   SQK+R
Sbjct:   54 SAPEPDPALEEFQEQSRFWVQKVLVPIIMLIGVIGNTVTIFIMTQRRMRSSTNWYLAALAIFDMSYLVFSFALSFQHYPHIHDSQ---FYAYWKFWPYMLTITDASSNSSVWITVTFTIERYIAVCYPMKGKIYCTESRAKKMIVIVFLSCFLITLPTAFEWNIIEIVNPITNETQIRADYSELGRNPVYKSVYYWFISVVFIMIPFILLAVFNAFLIKSVHSSKSRRKTMT----------------------------RRRETGDQARQESKITVMLIAVVILFLICQLPTAVILLYEAFHHVTPSSNEDLLLRGLGNIFNFLMAINAAGNFVLYCLLSQKYR 367
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A4Z2DHY3 (FMRFamide receptor OS=Schistosoma japonicum OX=6182 GN=EWB00_000780 PE=4 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 6.188e-38
Identity = 121/395 (30.63%), Postives = 195/395 (49.37%), Query Frame = 2 
Query:   89 NATSVDPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVM---ICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDA---------------------NSSTFSQQDRSLINNRLKHS--------------------------------TNVIDQYKTTYLLVIVVVTFCCLQTPSAI--------NYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            N   +D IL  +RLIC KI+ P++C  G + N +NII+LTR  M SSTN+YL +VS+ D+ YLL  +  SL LY+ +R+     + I  I      F SN T+WLTVCFT+ER +V+  P   R +CT  +A+ +++       +LT P+ F R IK  + P N  +      +  T F   + + GY  ++ ++F+++P+++L + N+LLI+ +  A  KR  L+    QHS    I+                        +T SQ    ++ + L+ S                                T + +Q++ T +L+++V+ F  LQ PS +        N  I+++        LI+ N  N+LL ++AA+NF+ YS FS KFR
Sbjct:   42 NLEYLDSILNTMRLICGKILTPLLCIIGFIANFINIIILTREWMSSSTNVYLTAVSLCDLFYLLFTYLFSLWLYQTLREFAPFAYCITIIHGTANLF-SNTTTWLTVCFTLERYIVISSPLIGRHYCTKQRARYIVLGIFCICTLLTLPDYFKRTIK--WIPINVTLNHYQFIVVDTQFNQLLTQFGYDYVNQIIFVILPMILLIIFNTLLIRSVFHANHKRYLLT---KQHSNNNKINTLHHHSNQINTIDNNNDNQLLNQQATTSQLAPIIVRDALEASLRTTINITSSITQSFRVLPTSIDLLPSMNIKRTKLGEQHRITLMLIVIVIAFVLLQLPSMVPTITINLWNTGIMKSTQYTKKCLLIYANISNVLLIINAALNFVFYSLFSSKFR 430
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A0R3S7U7 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS154 PE=4 SV=1)

HSP 1 Score: 148.288 bits (373), Expect = 2.376e-36
Identity = 116/341 (34.02%), Postives = 189/341 (55.43%), Query Frame = 2 
Query:  119 HIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICC--IRKTSFYNRIQRH-GYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHN------SQHSTR-LNIDA---NSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAI----NYVIVET-RPNRSISK--LIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            + RLI  KI+ P+IC  GI+ NI+NIIVLTR  M SSTN+YL +VS+ D+ YL      +L +Y     S   ++A+  IF  + +  SN T+WLT+ FT+ER + +  P    + CT  KAK++++     AFILT P+    +IK     + T++      +  S Y  + ++ GY  ++ + F+++P ++LA+ NSLLI+  + AK  R  ++         +Q++++ + I     N++    Q RS    R   S    +Q + T +L+ +VV F  LQTPS +    N+++ E  R + +     L+F N  N+LL ++A +NF+ YS FS KFR
Sbjct:   11 YARLIFAKILTPIICTTGIVVNIINIIVLTRSWMKSSTNVYLTAVSVTDMMYLFFSLLFTLYIYPTFNTSATYMYALP-IFRGIANLFSNITTWLTLSFTIERFINISYPIFGHRVCTRGKAKRIVMGVCIIAFILTFPDFLQSKIKSPLDSNGTLIPGGKYEQTDSDYAPVLKNIGYVYINQLAFVILPFILLAIFNSLLIQKGLEAKRNRQGMAKQELDRHPKAQYASKGMEIAKSCLNATVAVAQIRSNSTRRAIFS----EQQRITVMLISIVVAFLILQTPSTVISIANHILTEEQRKDENFFSIILVFSNISNVLLFINATLNFVFYSLFSVKFR 346
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000054912.1 (thyrotropin-releasing hormone receptor-like [Source:NCBI gene;Acc:103035526])

HSP 1 Score: 64.3142 bits (155), Expect = 7.796e-11
Identity = 84/325 (25.85%), Postives = 147/325 (45.23%), Query Frame = 2 
Query:  155 VICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVI--------VLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGY---FKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQ--HSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            +IC  GI  N++ ++V+ R + M++ TN YL+S++I D+  LL+     L     V  S    +A     + L     N +S     FT+ER + +      +  CTV++AKK+I        + C+   F++ + E+            N V++ C        R+ R+ Y   + +   LF +IPL++  V+  L+ + I+      +NLS   S   H  R N     S   + ++  +++R           + T +L +VVV F  L  P     V+V +  +       F  FC + +  ++A+N I+Y+  SQKFR A
Sbjct:   38 LICGVGIAGNVMVVLVVLRTKHMMTPTNCYLVSLAIADLIVLLA---AGLPNISEVVASWIYGYAGCLCITYLQYLGINVSSCSITAFTVERYIAICHSIKAQFICTVSRAKKIIACVWIFTSLYCIMWFFLVDTHEMVYA---------NGVIVRCGY------RVSRNLYMPVYFLDFTLFYVIPLIVATVLYGLIAR-ILFMNPLPSNLSERGSDSIHQGRTNSTVKVSC--KPNKGAVSSR----------KQVTKMLAVVVVLFALLWMPYR-TLVVVNSLMDPPYLNTWFLLFCRMSIYTNSAINPIIYNAMSQKFRTA 330
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: trhrb (thyrotropin-releasing hormone receptor-like [Source:NCBI gene;Acc:103029490])

HSP 1 Score: 63.5438 bits (153), Expect = 1.528e-10
Identity = 85/334 (25.45%), Postives = 152/334 (45.51%), Query Frame = 2 
Query:  125 RLICTKIILPVICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLS--MFCVSLQLYKRVRQSQNLLFAIVWIFSP-----LTSFSS---NATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKT-SFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYI-ITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            +LI T I+L  IC  GI+ N++ I +VLT + M + TN YL+S++  D+  L++  +  V+  LY              W+F       +T F     NA+S     FT+ER + +  P   +  CT T+AK++I+    T  +      +  +I+     D T++ C  + + + Y  I    YF    V F++ PL +  V+  L+ + + +    K  + + H+  +S              +   L ++    ST    + + T +L +VV+ F  L  P     V+V +    +     F  FC   + +++A+N ++Y+  SQKFR A
Sbjct:   22 KLISTLIVL-TICALGIVGNVMVILVVLTTKHMRTPTNCYLVSLAAADLMVLVAAGLPSVADSLYGS------------WLFGRVGCLCITYFQYLGINASSCSITAFTVERYIAICHPIRAQSLCTYTRAKRIILGVWVTTSLYCVMWFYLADIEELVYEDATIVSCAYKVSRNLYLPI----YFFDFGVFFVL-PLTLSTVLYGLIARILFLNPLPKTKSKNGHDGVYS------------GNKTNGLKSSSQCSSTTAASRRQVTKMLAVVVILFAVLWMPYR-TLVVVNSFLQEAYLDTWFLLFCRTCVYLNSAINPVIYNAMSQKFRAA 324
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: TRHR (thyrotropin-releasing hormone receptor [Source:NCBI gene;Acc:103040459])

HSP 1 Score: 63.1586 bits (152), Expect = 1.759e-10
Identity = 75/313 (23.96%), Postives = 145/313 (46.33%), Query Frame = 2 
Query:  158 ICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFC--VSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            +C  GI+ N + I +VLT + M + TN YL+S+++ D+  L +     ++  L+++         +I +    L     NA+S     FT+ER + +  P   +  CT+++AKK+I L  +   +         +++     + TV+IC  +     +R Q    +     LF ++PL++  V+  L+ + +I        L     ++S       N+S+ +Q+          +ST    + + T +L +VV+ F  L  P     V+V +   +      F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   40 VCGLGIIGNAMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPNITDSLFEQWVYGYAGCLSITY----LQYVGINASSCSITAFTVERYIAICHPIRAQSLCTLSRAKKIIALVWTFTGLYCVMWFCLADLEQQTHGNTTVVICAYK----VSRTQYLPIYFTDFALFYVLPLLLATVLYGLIARILIL-----NPLPSDPKENSKAWRKSTNTSSSTQRAA----KSSSYSTTATSRRQVTKMLAVVVILFALLWMPYR-TLVVVNSFLEKPYLDTWFVLFCRICIYLNSAINPVIYNAMSQKFRAA 334
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: trhr2 (thyrotropin-releasing hormone receptor-like [Source:NCBI gene;Acc:103031192])

HSP 1 Score: 55.4546 bits (132), Expect = 6.209e-8
Identity = 73/338 (21.60%), Postives = 146/338 (43.20%), Query Frame = 2 
Query:  155 VICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSP--------LTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVI--------VLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGY---FKMSAVLFIMIPLVILAVVNSLLIKYIITA-------KGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            ++C  GI+ NI+ + +VLT R M + TN YL+S+++ D++ L++    ++        S++L+    W++          L     N +S     FT+ER + +  P   +  CTV++AK++I        V C+   F++         ++C +                  R+ R  Y   + +   +F +IPL++   +  L+ + +  +        G  T  +L   + S +  +DA      +   +L + +           + T +L +VV+ F  L  P     V++ +  ++      F  FC   +  ++A+N ++Y+  SQKFR A
Sbjct:   42 LVCGVGIVGNIMVVLVVLTTRHMRTPTNCYLVSLAVADLTVLVAAGLPNI--------SESLM--ATWVYGHAGCLGITYLQYLGINVSSCSITAFTVERYIAICHPMRAQTVCTVSRAKRIIAGVWAFTCVYCMLWLFLVDIQVNSDGRVQCGY------------------RVSRDLYLPIYLIDFAIFYVIPLLLAIALYGLIARILYLSPLPHPPDSGTVTATTL---RRSCKEPVDAVKGRQGRPKSALSSRK-----------QVTKMLAVVVILFALLWMPYR-TLVLINSFVSKPYLDAWFLLFCRTCIYANSAINPVVYNLMSQKFRSA 336
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: CCKBR (cholecystokinin receptor-like [Source:NCBI gene;Acc:103038142])

HSP 1 Score: 50.447 bits (119), Expect = 2.202e-6
Identity = 68/329 (20.67%), Postives = 142/329 (43.16%), Query Frame = 2 
Query:  194 IIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLL-------IKYIITAKGKRTNLSLHNSQHSTRLNIDANS-------------------STFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTF--CCLQTPSAINYVIVETRPNRSISKLIFG---NFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            +++L  + M + TN +LLS+++ D+  ++++FC+       + +      A+  I + L   S + +++  +   +ER   +  P   R W T + A KVI +    +F++ +P      +    +P+NT+     R     +++Q+     +  VLF  IP V++     L+       I++ +  K  +  +    S   +  N D +                    ++ ++ DR   N      T ++ + +   +L+++V  F  C +   SA  +         S  +L+ G   +F +LL   SA +N I+Y F +++FR A
Sbjct:   72 VVLLVNKRMRTVTNSFLLSLAVSDL--MMAVFCMPFTFIPNLLEDFIFGAAMCKIVAYLMGISVSISTFSLMAIAIERYSAICNPLKSRAWQTRSHAYKVIAVTWVASFLIMTPYPIVSTLVNYTKPNNTITRHMCRHDWPKDQVQQAWCILLLFVLFF-IPGVVMITAYGLISRELYRGIQFELEQKKGQCGIKNGASTPVSTGNDDGDGCYIQVSKRPNSMEMSTLTLTSSAKVDRPRSNT---SETKLMAKKRVIRMLIVIVTMFFICWMPLYSANTWRAFHP---ASAHRLLSGAPISFIHLLSYTSACVNPIIYCFMNKRFRKA 391
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Match: trhrb (thyrotropin-releasing hormone receptor b [Source:ZFIN;Acc:ZDB-GENE-060503-382])

HSP 1 Score: 68.5514 bits (166), Expect = 4.792e-13
Identity = 86/344 (25.00%), Postives = 156/344 (45.35%), Query Frame = 2 
Query:   95 TSVDPILEHI----RLICTKIILPVICWPGIMCNILNIIVLTR-RSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTA-------FILTSPEIFSREIKCDFQPDNTVMICCIRKT-SFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
             ++ P  +H     R +   ++L  IC  GI+ N++ ++V+ R + M + TN YL S++I D+  LL+    ++     + +S    +A     + L     N +S     FT+ER L +  P   +  CTV++AK+++ L  S+        F L      S+       P + V  C  R + + Y  I    +F  +A  F ++PLV+  V+ +L+ + ++      +  +L        L + A  S         +N R K + +   + + T +L +VV+ F  L  P  +  V+V +  +       F  FC L L  ++A+N ++Y+  SQKFR A
Sbjct:   18 AALSPPPDHYTATYRAVSLALVL-AICGAGIVGNVMIVLVVVRTKHMRTPTNYYLGSLAIADLLVLLAAGLPNVS--DSLAESWVYGYAGCLAITYLQYLGINVSSCSITAFTLERYLAICHPIRAQSLCTVSRAKRILALVWSSTAIYCLVWFFLVDVHPRSQGGGGGEDPRSNVTECGYRVSRNLYLPIY---FFDFAA--FYVLPLVLACVLYALIARVLLLPPPPASR-TLAAPAVPLSLPLAAVCSGAVPS----VNRRGKSAYS--SRKQVTKMLAVVVLLFAVLWLPYRM-LVVVNSFVSSPYHDAWFLLFCRLCLYANSAINPVVYNAMSQKFRAA 345
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr1b (TRHR1b protein [Source:NCBI gene;Acc:100533509])

HSP 1 Score: 73.559 bits (179), Expect = 8.865e-14
Identity = 84/327 (25.69%), Postives = 156/327 (47.71%), Query Frame = 2 
Query:  137 TKIILPVICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSP-----LTSFSS---NATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIR-KTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            + ++L VIC  GI+ NI+ I +VLT + M + TN YL+S+++ D+  L +    ++          + +FA  W+F       +T F     NA+S     FT+ER + +  P   +  CT+++AKK+I+   +   I      +  +I+     + T++ C  R    FY  +    YF    V F++ PL++ AV+  L+ + +         L+   S+H  +    AN+       ++   N    S+    + + T +L +VV+ F  L  P     V+V +  +++     F  FC + + +++A+N ++Y+  SQKFR A
Sbjct:   28 SSLLLFVICASGIVGNIMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPAIT---------DSIFA-TWVFGRYGCLCITYFQYLGINASSCSITAFTIERYIAICHPIKAQFLCTLSRAKKIILFVWAFTSIYCVMWFYLSDIQELVYENITIITCGYRVPRKFYLPV----YFFDFGVFFVL-PLLLSAVLYGLIARILF--------LNPLPSEHKAKKKSGANNP------KTSCKNSRHSSSTATSRRQVTKMLAVVVILFAVLWMPYR-TLVVVNSFLDQAYLDSWFLLFCRICIYLNSAINPVIYNAMSQKFRAA 324
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr2 (TRHR2 protein [Source:NCBI gene;Acc:100533510])

HSP 1 Score: 63.1586 bits (152), Expect = 1.805e-10
Identity = 75/326 (23.01%), Postives = 145/326 (44.48%), Query Frame = 2 
Query:  155 VICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFC--VSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVI--------VLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAV---LFIMIPLVILAVVNSLLIKYI-ITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            ++C  GI+ N++ + +V T R M + TN YL+S++I D++ L++     VS  L       Q     I +    L     N +S     FT+ER + +  P   +  CTV++AK++I        V C+   F++         ++C +                  R++R  Y  +  +   +F +IPL++  V+ +L+ + + ++    + + S    + S R   +A       + +S +++R           + T +L +VV+ F  L  P     V++ +  +       F  FC   +  ++A+N ++Y+  SQKFRLA
Sbjct:   31 LVCGVGIIGNVMVVLVVFTTRHMRTPTNCYLVSLAIADLTVLVAAGLPNVSDSLTGTWIFGQAGCLGITY----LQYLGINVSSCSITAFTVERYIAICHPMKAQTVCTVSRAKRIIAGVWIFTCVYCMLWLFLVDIQVGPDGHVQCGY------------------RVKRELYLPIYLIDFAIFYVIPLLLAIVLYALIARILYLSPLPHQPDTSATTLRRSCRDTSEAARPGRQGRPKSALSSR----------KQVTKMLAVVVILFALLWMPYR-TLVLINSFVSTPYLNAWFLLFCRTCIYANSAINPVIYNAMSQKFRLA 323
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr2 (TRHR2 protein [Source:NCBI gene;Acc:100533510])

HSP 1 Score: 61.6178 bits (148), Expect = 6.539e-10
Identity = 75/332 (22.59%), Postives = 147/332 (44.28%), Query Frame = 2 
Query:  155 VICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSP--------LTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVI--------VLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGY---FKMSAVLFIMIPLVILAVVNSLLIKYI-ITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            ++C  GI+ N++ + +V T R M + TN YL+S++I D++ L++    ++        S +L     WIF          L     N +S     FT+ER + +  P   +  CTV++AK++I        V C+   F++         ++C +                  R++R  Y   + +   +F +IPL++  V+ +L+ + + ++    + + S    + S R   +A       + +S +++R           + T +L +VV+ F  L  P     V++ +  +       F  FC   +  ++A+N ++Y+  SQKFRLA
Sbjct:   39 LVCGVGIIGNVMVVLVVFTTRHMRTPTNCYLVSLAIADLTVLVAAGLPNV--------SDSL--TGTWIFGQAGCLGITYLQYLGINVSSCSITAFTVERYIAICHPMKAQTVCTVSRAKRIIAGVWIFTCVYCMLWLFLVDIQVGPDGHVQCGY------------------RVKRELYLPIYLIDFAIFYVIPLLLAIVLYALIARILYLSPLPHQPDTSATTLRRSCRDTSEAARPGRQGRPKSALSSR----------KQVTKMLAVVVILFALLWMPYR-TLVLINSFVSTPYLNAWFLLFCRTCIYANSAINPVIYNAMSQKFRLA 331
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr (thyrotropin releasing hormone receptor [Source:NCBI gene;Acc:100533508])

HSP 1 Score: 54.6842 bits (130), Expect = 7.675e-8
Identity = 72/318 (22.64%), Postives = 138/318 (43.40%), Query Frame = 2 
Query:  143 IILPVICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDAN--SSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            +++ +IC  GI+ N++ I +VLT + M + TN YL+S++  D+  L +    ++     +R      +A     +       NA+S     FT+ER + +  P   +  CT+++AKK+I+L  +   +     +F  + K     DN V++ C  K S   R      +     +F ++PL++  V+  L+ + +         L       S+R   D+    S+  Q+ +  +   L     +       Y  ++VV +F                   ++     F  FC L + +++A+N ++Y+  SQKFR A
Sbjct:   31 LLVSLICGVGIVGNMMVILVVLTTKHMRTPTNCYLVSLAAADLMVLTAAGLPNIT--DALRGQWVYGYAGCLGITYFQYLGINASSCSITAFTVERYIAICHPIKAQFLCTLSRAKKIIMLVWALTSVYCVMWLFLSDTK-KLVYDNVVLLTCAYKVS---RSHYLPIYFTDFTVFYVLPLLLATVLYGLIARILFL-----NPLPADPKASSSRGCGDSQRRESSRRQEPQPGVTKMLAVVVVLFAVLWMPYRTLVVVNSFL-----------------EKAYLDTWFLLFCRLCIYLNSAINPVIYNAMSQKFRTA 320
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr (thyrotropin releasing hormone receptor [Source:NCBI gene;Acc:100533508])

HSP 1 Score: 55.0694 bits (131), Expect = 7.681e-8
Identity = 72/322 (22.36%), Postives = 142/322 (44.10%), Query Frame = 2 
Query:  143 IILPVICWPGIMCNILNI-IVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYII------TAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            +++ +IC  GI+ N++ I +VLT + M + TN YL+S++  D+  L +    ++     +R      +A     +       NA+S     FT+ER + +  P   +  CT+++AKK+I+L  +   +     +F  + K     DN V++ C  K S   R      +     +F ++PL++  V+  L+ + +         KG  ++     +  + R+   ++SS+ +   R  +   L     +       Y  ++VV +F                   ++     F  FC L + +++A+N ++Y+  SQKFR A
Sbjct:   39 LLVSLICGVGIVGNMMVILVVLTTKHMRTPTNCYLVSLAAADLMVLTAAGLPNIT--DALRGQWVYGYAGCLGITYFQYLGINASSCSITAFTVERYIAICHPIKAQFLCTLSRAKKIIMLVWALTSVYCVMWLFLSDTK-KLVYDNVVLLTCAYKVS---RSHYLPIYFTDFTVFYVLPLLLATVLYGLIARILFLNPLPADPKGASSHKWKREASQAGRMISASSSSSTTASSRRQVTKMLAVVVVLFAVLWMPYRTLVVVNSFL-----------------EKAYLDTWFLLFCRLCIYLNSAINPVIYNAMSQKFRTA 337
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000043889.1 (SMESG000043889.1)

HSP 1 Score: 675.241 bits (1741), Expect = 0.000e+0
Identity = 335/336 (99.70%), Postives = 336/336 (100.00%), Query Frame = 2 
Query:   80 MYCNATSVDPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 1087
            MYCNATSVDPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLS+HNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA
Sbjct:    1 MYCNATSVDPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSIHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLA 336
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000013112.1 (SMESG000013112.1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.799e-17
Identity = 93/318 (29.25%), Postives = 147/318 (46.23%), Query Frame = 2 
Query:  137 TKIILPVICWPGIMCNILNIIVLTRRSMISSTNIYLLSVSIMDISYLL-SMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIM--IPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            T+II  ++   GI+ N L++IVL  + M SS +IYLL++++ D   L+ ++F   L  ++ +R    + F I   F P    +  AT W+TV  T ER   V  P   + + ++ K+   ++L    +     P  +  EI           +     T     I  H ++   A + IM  IPL++L+ +N +LI+             L NSQ    LN D N S  S + R     R++   NV      T ++V+VV  F   Q P+ I  +    +P   IS  I     N L+ +++A+NFILY  F QKFR
Sbjct:    8 TQIITIIVISFGIIGNFLSVIVLKNKVMRSSVSIYLLALTLWDTVLLICALFIGPLMRFENLRV---IFFKI---FYPPALVAQTATIWITVGLTCERYFAVCFPLKAQFFISMKKSFWCVILISLFSIFYNVPR-WLEEIPMSINNSEHTFVNHSDST-----IGFHKFYYSYAYIVIMFFIPLLVLSSMNYMLIR------------ELKNSQLYV-LN-DTNKSLISSKSR-----RIRSDNNV------TRMIVVVVSIFIFCQFPALIYNIKFGIQPANDISWEIISEIRNFLVILNSAVNFILYCAFGQKFR 288
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000002928.1 (SMESG000002928.1)

HSP 1 Score: 73.9442 bits (180), Expect = 4.602e-14
Identity = 84/343 (24.49%), Postives = 148/343 (43.15%), Query Frame = 2 
Query:  137 TKIILPVICWPGIMCNILNIIVLTRRSM-ISSTNIYLLSVSIMDISYLLSMFCV---------SLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIKCDFQPDNTVM----------------ICCIRKTSFYNRIQRHGYFKM-SAVLF-IMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            + +++P     GI+ NIL ++VL+++ M  S+TN YL+++SI D   L+S             S ++  +  Q   +   +  IF P        + WLTV F+++R  ++  PF  ++ CTV ++K VI++    +     P  F         P N  +                I  I  T F +  Q   Y+ + S ++F I+IPL+++  +N  LI + +    KR N   H                            L   +  I +  T  +L+ V+V F   Q PSAI++++            I+    N L+ +++A+N + Y FFS++FR
Sbjct:   19 SGVLVPTFSTIGIIGNILCLLVLSQKQMRCSTTNWYLMALSISDSLVLVSTILTVIKETIPFDSTKMRWQSWQKYPITLDLFIIFHPFAILFQVTSIWLTVVFSLDRYFMICHPFMAQRICTVKRSKHVIIITYILSTCYNVPRFFENYKHQMMLPFNVSLPNVTYDHLKPIQEYPQISMIDTTVFGSSWQFKVYYHLWSWIIFVIIIPLMLIIYMNIYLI-FEVRKSIKRLNSMGH---------------------------FLPACSEEITRIDTNVMLIGVIVIFLICQIPSAISHILWAL----DFPLFIYNEIGNFLIILNSALNIVPYYFFSRRFR 329
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000042142.1 (SMESG000042142.1)

HSP 1 Score: 67.3958 bits (163), Expect = 7.507e-12
Identity = 86/325 (26.46%), Postives = 154/325 (47.38%), Query Frame = 2 
Query:  170 GIMCNILNIIVLTRRSMIS-STNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFS---------REIKCDFQPD---NTVMICCIRK--TSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKT-TYLLVIVVVTFCCLQTPSAINYVIVETR--PN--RSISKLI-FGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            G + N L+ +VL R+SM   S+ IYL +++I D   LL         +      +N   +   +F  +   SS  + WL V  T+ER+L++ +PF   K+   ++AK +IV  +  +F  TS   F          + +  +F  D   N++  C  +   T F N      +F +    +  IPL +L + N +++  I  A+      ++HNS  +T  N D N +  +   R+ +  R+K S++   + K  T +L+IV  +F    +P  I  ++++ +  PN  R +++L+       +L+ V+ A+NF LY     KFR
Sbjct:   82 GSIGNFLSAVVLCRKSMSHISSYIYLATLAIFDELILLCGLFRKWIEHVTDWSLENHSISFCKLFQVIGVSSSFISVWLIVTLTVERVLIIKRPFEASKYAKASRAKYIIVSLIIISFT-TSCHFFETVTLQNLNHKNVNTNFSSDKGSNSIKKCQFKTEYTKFTN-----AWFFIDGAFYSWIPLFLLIINNLIILSEIYKAR------NIHNSMINT--NHDENKTLGTSIVRTQLPRRMKESSSRNRETKQLTVMLLIVSFSFLITTSPFVILKLLIKLKGYPNGDRKLAQLVLLDGIFEMLMYVNHAINFYLYCATGNKFR 392
[Close]
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000028684.1 (SMESG000028684.1)

HSP 1 Score: 65.0846 bits (157), Expect = 3.641e-11
Identity = 88/322 (27.33%), Postives = 150/322 (46.58%), Query Frame = 2 
Query:  161 CWPGIMCNILNIIVLTRRSMI-SSTNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIV---WI------FSPLTSFSSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILTSPEIFSREIK-CDFQPDNTVMICCIRK-TSFYNRIQRHGYFKMSAVLFIMIPLVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDRSLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIV---ETRPNRSISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFR 1081
            C  GI+ NI NI+VLTR +MI S+TN  L+ ++I D+  ++    + ++ Y       +LL       W+       S   SF S A  WLTV   + R + +  P      C++  A K   +     F++T P +   +I+ C    DN +M+    K  S +  I +  ++ + A LF +IP V+L  +   LI  +  A  +++NL L+N++              SQ+       + KH      + +TTY+L+ VV+ F   + P  +  ++    E    +   KL  G+  + L  V+ + NFILY+  S++FR
Sbjct:   45 CIFGIVTNIANILVLTRPTMITSATNWLLMCLAIADLLTMVVYLPILIKFYISSNFGPDLLLHTDSWNWVVYQKFMVSCTISFHSIAV-WLTVSLAIFRFICIYMPIKGPPLCSIPNASKTTFVISILCFLVTIPNMVVTKIQSCQNAKDNRLMVFYFLKIDSSFEMISKMNFW-LQATLFKLIPSVVLTALTVGLILSMKKATQRQSNL-LNNTK--------------SQR-------KAKHR-----EQRTTYMLLAVVLLFLLTEAPQGLLMLLSYFKEGFYEKVYEKL--GDLIDFLTLVNESTNFILYTTMSKQFR 335
The following BLAST results are available for this feature:
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
TRHR4.894e-1223.08thyrotropin releasing hormone receptor [Source:HGN... [more]
TRHR4.894e-1223.08thyrotropin releasing hormone receptor [Source:HGN... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sprr-13.662e-1324.28Sex Peptide Receptor (Drosophila) Related [Source... [more]
sprr-13.662e-1324.28Sex Peptide Receptor (Drosophila) Related [Source... [more]
frpr-85.469e-1323.19FMRFamide Peptide Receptor family [Source:UniProt... [more]
frpr-151.372e-924.58FMRFamide Peptide Receptor family [Source:UniProt... [more]
frpr-151.372e-924.58FMRFamide Peptide Receptor family [Source:UniProt... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Proc-R3.429e-1633.53gene:FBgn0029723 transcript:FBtr0100552[more]
Proc-R3.429e-1633.53gene:FBgn0029723 transcript:FBtr0070713[more]
Proc-R3.429e-1633.53gene:FBgn0029723 transcript:FBtr0100551[more]
Proc-R3.429e-1633.53gene:FBgn0029723 transcript:FBtr0070714[more]
Proc-R3.429e-1633.53gene:FBgn0029723 transcript:FBtr0345320[more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trhra6.225e-1525.71thyrotropin-releasing hormone receptor a [Source:Z... [more]
trhra4.816e-1425.99thyrotropin-releasing hormone receptor a [Source:Z... [more]
trhra4.989e-1425.99thyrotropin-releasing hormone receptor a [Source:Z... [more]
trhra5.206e-1425.99thyrotropin-releasing hormone receptor a [Source:Z... [more]
trhrb1.482e-1024.70thyrotropin-releasing hormone receptor b [Source:Z... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kiaa1324l1.468e-1225.54KIAA1324-like [Source:Xenbase;Acc:XB-GENE-5954588][more]
epx1.229e-1022.64eosinophil peroxidase [Source:Xenbase;Acc:XB-GENE-... [more]
ENSXETT00000016730.12.447e-1023.85thyrotropin-releasing hormone receptor 3 [Source:N... [more]
ENSXETT00000031646.15.936e-1023.77thyrotropin-releasing hormone receptor 3 [Source:N... [more]
ENSXETT00000016751.16.825e-1023.77thyrotropin-releasing hormone receptor 3 [Source:N... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Trhr2.500e-1124.06thyrotropin releasing hormone receptor [Source:MGI... [more]
Trhr2.500e-1124.06thyrotropin releasing hormone receptor [Source:MGI... [more]
Trhr2.500e-1124.06thyrotropin releasing hormone receptor [Source:MGI... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O93603|TRFR_CHICK1.984e-1424.54Thyrotropin-releasing hormone receptor OS=Gallus g... [more]
sp|O46639|TRFR_BOVIN1.028e-1123.62Thyrotropin-releasing hormone receptor OS=Bos taur... [more]
sp|Q28596|TRFR_SHEEP1.334e-1124.31Thyrotropin-releasing hormone receptor OS=Ovis ari... [more]
sp|P34981|TRFR_HUMAN2.350e-1123.08Thyrotropin-releasing hormone receptor OS=Homo sap... [more]
sp|P21761|TRFR_MOUSE1.749e-1024.06Thyrotropin-releasing hormone receptor OS=Mus musc... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5J4P3C71.848e-5032.85G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A1S3IC781.505e-4032.33FMRFamide receptor OS=Lingula unguis OX=7574 GN=LO... [more]
A0A087TQJ14.422e-3831.30FMRFamide receptor (Fragment) OS=Stegodyphus mimos... [more]
A0A4Z2DHY36.188e-3830.63FMRFamide receptor OS=Schistosoma japonicum OX=618... [more]
A0A0R3S7U72.376e-3634.02G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000054912.17.796e-1125.85thyrotropin-releasing hormone receptor-like [Sourc... [more]
trhrb1.528e-1025.45thyrotropin-releasing hormone receptor-like [Sourc... [more]
TRHR1.759e-1023.96thyrotropin-releasing hormone receptor [Source:NCB... [more]
trhr26.209e-821.60thyrotropin-releasing hormone receptor-like [Sourc... [more]
CCKBR2.202e-620.67cholecystokinin receptor-like [Source:NCBI gene;Ac... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
trhrb4.792e-1325.00thyrotropin-releasing hormone receptor b [Source:Z... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trhr1b8.865e-1425.69TRHR1b protein [Source:NCBI gene;Acc:100533509][more]
trhr21.805e-1023.01TRHR2 protein [Source:NCBI gene;Acc:100533510][more]
trhr26.539e-1022.59TRHR2 protein [Source:NCBI gene;Acc:100533510][more]
trhr7.675e-822.64thyrotropin releasing hormone receptor [Source:NCB... [more]
trhr7.681e-822.36thyrotropin releasing hormone receptor [Source:NCB... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000043889.10.000e+099.70SMESG000043889.1[more]
SMESG000013112.11.799e-1729.25SMESG000013112.1[more]
SMESG000002928.14.602e-1424.49SMESG000002928.1[more]
SMESG000042142.17.507e-1226.46SMESG000042142.1[more]
SMESG000028684.13.641e-1127.33SMESG000028684.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022033 ID=SMED30022033|Name=G_PROTEIN_RECEP_F1_2 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1333bp
ATTGCATTCTATATAATTAGAGTAAGTTGGGTTCTTAGTAGAAATAGTTA
TTCCATTCTAATACAAATTTAACCTATCAATGTACTGCAATGCCACCTCT
GTTGATCCGATTCTTGAGCATATCAGATTAATTTGTACCAAAATTATTCT
ACCAGTCATCTGTTGGCCGGGAATAATGTGCAATATTTTAAACATCATCG
TCCTTACTCGCCGTTCAATGATCAGTTCAACGAATATCTATCTTTTGTCC
GTGTCAATTATGGATATTTCATATTTACTCTCGATGTTTTGCGTTTCACT
TCAGCTTTACAAGAGAGTTCGTCAGTCACAGAATTTATTATTTGCAATCG
TCTGGATATTTTCTCCCTTGACTTCATTCTCCAGCAATGCCACTTCATGG
TTGACGGTTTGTTTTACCATGGAGCGATTGTTGGTCGTTCTTAAACCGTT
CGCCATTCGGAAATGGTGTACGGTTACAAAAGCGAAAAAGGTGATAGTTC
TATGCCTGTCGACGGCTTTTATTTTGACAAGTCCAGAGATTTTTTCGAGG
GAAATTAAATGCGATTTTCAACCGGATAATACAGTCATGATTTGCTGTAT
TAGGAAGACTTCGTTTTATAATCGTATTCAGCGCCATGGGTATTTTAAAA
TGAGTGCGGTTTTGTTTATAATGATACCGTTGGTGATCTTAGCAGTCGTT
AATAGCCTGTTGATCAAATACATCATAACGGCGAAGGGTAAGCGAACTAA
TCTAAGTTTACACAACTCTCAACATTCGACTCGGTTGAACATCGATGCCA
ACTCGTCAACGTTTAGTCAACAAGACAGATCCTTGATCAACAATAGACTT
AAGCACTCTACAAATGTCATAGATCAGTACAAGACCACATATTTACTCGT
CATTGTTGTGGTGACATTTTGCTGTTTGCAGACCCCCAGCGCAATTAATT
ACGTAATCGTTGAAACGAGGCCAAATAGATCTATATCGAAATTAATTTTT
GGGAATTTTTGTAATCTACTTTTGGCAGTGAGCGCTGCCATGAATTTTAT
CCTTTACTCGTTTTTCTCGCAGAAATTTCGGTTGGCATTCAAAAAAACAT
TGTTCAAAAATTAAAAAAAAAAGAAAAAAAAATGGAAATTTTATTTCAAC
GATTTTATACAGATAATATATTATTACTGTGAATTCGATGTTGTTTTATT
TTATTATTTTTTCTTTCATTGAAAATTGGTGAAACGGTTTTTTTGTTTGT
CTTGTAAGTCGACGAAAAAAAAATTCTTTACAAGTTTGTGGAATAAATAC
CAGCTGTTTTGTTTGAATTTACCAATGGGGAAA
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protein sequence of SMED30022033-orf-1

>SMED30022033-orf-1 ID=SMED30022033-orf-1|Name=SMED30022033-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=345bp
MYCNATSVDPILEHIRLICTKIILPVICWPGIMCNILNIIVLTRRSMISS
TNIYLLSVSIMDISYLLSMFCVSLQLYKRVRQSQNLLFAIVWIFSPLTSF
SSNATSWLTVCFTMERLLVVLKPFAIRKWCTVTKAKKVIVLCLSTAFILT
SPEIFSREIKCDFQPDNTVMICCIRKTSFYNRIQRHGYFKMSAVLFIMIP
LVILAVVNSLLIKYIITAKGKRTNLSLHNSQHSTRLNIDANSSTFSQQDR
SLINNRLKHSTNVIDQYKTTYLLVIVVVTFCCLQTPSAINYVIVETRPNR
SISKLIFGNFCNLLLAVSAAMNFILYSFFSQKFRLAFKKTLFKN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR0194277TM_GPCR_serpentine_rcpt_Srw
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0008528G-protein coupled peptide receptor activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 98..120
score: 15.58
coord: 269..293
score: 21.09
coord: 51..72
score: 21.22
coord: 19..43
score: 17.75
coord: 189..212
score: 18.08
coord: 308..334
score: 26.12
IPR0194277TM GPCR, serpentine receptor class w (Srw)PFAMPF103247TM_GPCR_Srwcoord: 26..342
e-value: 1.0E-17
score: 64.4
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 11..344
e-value: 1.1E-45
score: 158.0
NoneNo IPR availablePANTHERPTHR46641FAMILY NOT NAMEDcoord: 5..339
NoneNo IPR availableCDDcd149787tmA_FMRFamide_R-likecoord: 22..337
e-value: 1.24096E-44
score: 153.172
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 20..343
NoneNo IPR availableTMHMMTMhelixcoord: 194..216
NoneNo IPR availableTMHMMTMhelixcoord: 271..293
NoneNo IPR availableTMHMMTMhelixcoord: 52..74
NoneNo IPR availableTMHMMTMhelixcoord: 20..42
NoneNo IPR availableTMHMMTMhelixcoord: 306..328
NoneNo IPR availableTMHMMTMhelixcoord: 86..108
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 34..326
score: 21.756