Phospholipid scramblase

Overview
NamePhospholipid scramblase
Smed IDSMED30022020
Length (bp)1005
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Phospholipid scramblase (SMED30022020) t-SNE clustered cells

Violin plots show distribution of expression levels for Phospholipid scramblase (SMED30022020) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Phospholipid scramblase (SMED30022020) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Phospholipid scramblase (SMED30022020) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30022020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30022020h1SMcG0003817 SmedASXL_009877SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30022020h1SMcG0003817 dd_Smed_v4_13534_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30022020h1SMcG0003817 dd_Smed_v6_13534_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Human
Match: PLSCR1 (phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092])

HSP 1 Score: 77.7962 bits (190), Expect = 1.169e-15
Identity = 78/277 (28.16%), Postives = 117/277 (42.24%), Query Frame = 3 
Query:   87 NMGVSNSKVDSEGQIVDP---PPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            N  V N  V + G    P   PP+     LE L  +  + + QQ+  +L E   G    N Y++ +  G  +    E  DC   C+R  CGP+R F +   DN  + ++ + R P RC + CC  C+     I I       +G+  Q    C P  +I +   E V  I GPC  C C  D+ F + + D +   VV                            GKI K WT         D +N  ++ P D+D   +A+++G+ FL+DFM+FE
Sbjct:   63 NQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQI--ELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDC---CTRNCCGPSRPFTLRIIDNMGQEVITLER-PLRCSSCCCPCCL---QEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQ--CVV----------------------------GKISKHWT-GILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFE 299
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Human
Match: PLSCR1 (phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092])

HSP 1 Score: 77.7962 bits (190), Expect = 1.266e-15
Identity = 78/277 (28.16%), Postives = 117/277 (42.24%), Query Frame = 3 
Query:   87 NMGVSNSKVDSEGQIVDP---PPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            N  V N  V + G    P   PP+     LE L  +  + + QQ+  +L E   G    N Y++ +  G  +    E  DC   C+R  CGP+R F +   DN  + ++ + R P RC + CC  C+     I I       +G+  Q    C P  +I +   E V  I GPC  C C  D+ F + + D +   VV                            GKI K WT         D +N  ++ P D+D   +A+++G+ FL+DFM+FE
Sbjct:   70 NQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQI--ELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDC---CTRNCCGPSRPFTLRIIDNMGQEVITLER-PLRCSSCCCPCCL---QEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQ--CVV----------------------------GKISKHWT-GILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFE 306
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Human
Match: PLSCR5 (phospholipid scramblase family member 5 [Source:HGNC Symbol;Acc:HGNC:19952])

HSP 1 Score: 72.0182 bits (175), Expect = 7.702e-14
Identity = 68/259 (26.25%), Postives = 105/259 (40.54%), Query Frame = 3 
Query:  141 PPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDA-WCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
            P V     LE L  L  + + QQ+  +L     G    N Y++ +  G  I   +E+  C N   R +C   R   +   DN+ R ++ + R P RC++ WC   C      I    G    +G+  QK     P  +I ++  E +  I GPC  C C  D+ F V T + K                                 GKI K W+      +  + +N  + +P D+D   +A ++G+ FL DFM+FE S
Sbjct:   50 PTVSLPPGLEYLSQLDLIIIHQQV--ELLGMILGTETSNKYEIKNSLGQRIYFAVEESICFN---RTFCSTLRSCTLRITDNSGREVITVNR-PLRCNSCWC--PCYLQELEIQAPPG--TIVGYVTQKWDPFLPKFTIQNANKEDILKIVGPCVTCGCFGDVDFEVKTINEK------------------------------LTIGKISKYWSGFVN-DVFTNADNFGIHVPADLDVTVKAAMIGACFLFDFMFFEHS 267
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Human
Match: PLSCR5 (phospholipid scramblase family member 5 [Source:HGNC Symbol;Acc:HGNC:19952])

HSP 1 Score: 72.0182 bits (175), Expect = 7.702e-14
Identity = 68/259 (26.25%), Postives = 105/259 (40.54%), Query Frame = 3 
Query:  141 PPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDA-WCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
            P V     LE L  L  + + QQ+  +L     G    N Y++ +  G  I   +E+  C N   R +C   R   +   DN+ R ++ + R P RC++ WC   C      I    G    +G+  QK     P  +I ++  E +  I GPC  C C  D+ F V T + K                                 GKI K W+      +  + +N  + +P D+D   +A ++G+ FL DFM+FE S
Sbjct:   50 PTVSLPPGLEYLSQLDLIIIHQQV--ELLGMILGTETSNKYEIKNSLGQRIYFAVEESICFN---RTFCSTLRSCTLRITDNSGREVITVNR-PLRCNSCWC--PCYLQELEIQAPPG--TIVGYVTQKWDPFLPKFTIQNANKEDILKIVGPCVTCGCFGDVDFEVKTINEK------------------------------LTIGKISKYWSGFVN-DVFTNADNFGIHVPADLDVTVKAAMIGACFLFDFMFFEHS 267
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Human
Match: PLSCR1 (phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092])

HSP 1 Score: 70.0922 bits (170), Expect = 2.597e-13
Identity = 65/242 (26.86%), Postives = 102/242 (42.15%), Query Frame = 3 
Query:  183 LQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            +  + + QQ+  +L E   G    N Y++ +  G  +    E  DC   C+R  CGP+R F +   DN  + ++ + R P RC + CC  C+     I I       +G+  Q    C P  +I +   E V  I GPC  C C  D+ F + + D +                                 GKI K WT         D +N  ++ P D+D   +A+++G+ FL+DFM+FE
Sbjct:   24 IDQILIHQQI--ELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDC---CTRNCCGPSRPFTLRIIDNMGQEVITLER-PLRCSSCCCPCCL---QEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQ------------------------------CVVGKISKHWT-GILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFE 225
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Celegans
Match: scrm-1 (Phospholipid scramblase [Source:UniProtKB/TrEMBL;Acc:Q7JKP1])

HSP 1 Score: 72.0182 bits (175), Expect = 3.286e-14
Identity = 68/259 (26.25%), Postives = 100/259 (38.61%), Query Frame = 3 
Query:  138 PPPVY-YSRSLEVLDGLQNVRVQQ--QMPRDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRH---PCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            PP +      LE L  L  + V Q  ++   + +    N Y + + NG       E+   + CC R  CGP RGF M   DN +R ++ ++R           C      C     I       LG  +Q+C C + N  I+D     +  I GPCC   C C                 K+F I          K+A     N    G I K+W    +     D +   +  P D+D   + +L+G+ FL+DFM FE
Sbjct:   54 PPAIQGVPTGLEYLTYLDTIMVHQIKELIEIVTDWETKNKYVLKNANGEQCYYAFEE---SGCCERQCCGPQRGFVMHIVDNFKREVLTIKREFKCCGGGCCGCLACIGCCQQECIIETPSMGVLGIIRQRCGCMSSNYDIMDGDGNVIFQIDGPCCCMLCGCQ---------------DKEFPI----------KTA----NNGTVVGAITKKW-GGCFREAFTDADTFAVNFPGDLDVKLKGVLIGATFLIDFMEFE 279
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Celegans
Match: scrm-1 (Phospholipid scramblase [Source:UniProtKB/TrEMBL;Acc:Q7JKP1])

HSP 1 Score: 72.0182 bits (175), Expect = 3.286e-14
Identity = 68/259 (26.25%), Postives = 100/259 (38.61%), Query Frame = 3 
Query:  138 PPPVY-YSRSLEVLDGLQNVRVQQ--QMPRDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRH---PCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            PP +      LE L  L  + V Q  ++   + +    N Y + + NG       E+   + CC R  CGP RGF M   DN +R ++ ++R           C      C     I       LG  +Q+C C + N  I+D     +  I GPCC   C C                 K+F I          K+A     N    G I K+W    +     D +   +  P D+D   + +L+G+ FL+DFM FE
Sbjct:   54 PPAIQGVPTGLEYLTYLDTIMVHQIKELIEIVTDWETKNKYVLKNANGEQCYYAFEE---SGCCERQCCGPQRGFVMHIVDNFKREVLTIKREFKCCGGGCCGCLACIGCCQQECIIETPSMGVLGIIRQRCGCMSSNYDIMDGDGNVIFQIDGPCCCMLCGCQ---------------DKEFPI----------KTA----NNGTVVGAITKKW-GGCFREAFTDADTFAVNFPGDLDVKLKGVLIGATFLIDFMEFE 279
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Celegans
Match: scrm-1 (Phospholipid scramblase [Source:UniProtKB/TrEMBL;Acc:Q7JKP1])

HSP 1 Score: 72.0182 bits (175), Expect = 3.941e-14
Identity = 68/259 (26.25%), Postives = 100/259 (38.61%), Query Frame = 3 
Query:  138 PPPVY-YSRSLEVLDGLQNVRVQQ--QMPRDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRH---PCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            PP +      LE L  L  + V Q  ++   + +    N Y + + NG       E+   + CC R  CGP RGF M   DN +R ++ ++R           C      C     I       LG  +Q+C C + N  I+D     +  I GPCC   C C                 K+F I          K+A     N    G I K+W    +     D +   +  P D+D   + +L+G+ FL+DFM FE
Sbjct:   54 PPAIQGVPTGLEYLTYLDTIMVHQIKELIEIVTDWETKNKYVLKNANGEQCYYAFEE---SGCCERQCCGPQRGFVMHIVDNFKREVLTIKREFKCCGGGCCGCLACIGCCQQECIIETPSMGVLGIIRQRCGCMSSNYDIMDGDGNVIFQIDGPCCCMLCGCQ---------------DKEFPI----------KTA----NNGTVVGAITKKW-GGCFREAFTDADTFAVNFPGDLDVKLKGVLIGATFLIDFMEFE 279
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Celegans
Match: scrm-1 (Phospholipid scramblase [Source:UniProtKB/TrEMBL;Acc:Q7JKP1])

HSP 1 Score: 72.0182 bits (175), Expect = 3.951e-14
Identity = 68/259 (26.25%), Postives = 100/259 (38.61%), Query Frame = 3 
Query:  138 PPPVY-YSRSLEVLDGLQNVRVQQ--QMPRDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRH---PCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            PP +      LE L  L  + V Q  ++   + +    N Y + + NG       E+   + CC R  CGP RGF M   DN +R ++ ++R           C      C     I       LG  +Q+C C + N  I+D     +  I GPCC   C C                 K+F I          K+A     N    G I K+W    +     D +   +  P D+D   + +L+G+ FL+DFM FE
Sbjct:   54 PPAIQGVPTGLEYLTYLDTIMVHQIKELIEIVTDWETKNKYVLKNANGEQCYYAFEE---SGCCERQCCGPQRGFVMHIVDNFKREVLTIKREFKCCGGGCCGCLACIGCCQQECIIETPSMGVLGIIRQRCGCMSSNYDIMDGDGNVIFQIDGPCCCMLCGCQ---------------DKEFPI----------KTA----NNGTVVGAITKKW-GGCFREAFTDADTFAVNFPGDLDVKLKGVLIGATFLIDFMEFE 279
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Celegans
Match: scrm-2 (Phospholipid scramblase [Source:UniProtKB/TrEMBL;Acc:G5EEQ3])

HSP 1 Score: 64.3142 bits (155), Expect = 1.345e-11
Identity = 66/252 (26.19%), Postives = 96/252 (38.10%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHP-CRCDAWCCLDCVFCSHRI-TISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLC-DLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  L  V V Q   +++ E   G    N Y + ++NG       E+   +N   R  CG  RGF M   DN  + ++ ++R   C  D++C   C+     I TI       LG   Q   C     +I+D     +  + G  C   C C D  F + TPD   P                               G I K+W          D +   +  P D+D   +A+LLG+ FL+DF+ FE
Sbjct:   49 GLEYLAYLDTVMVHQ--VKEVLEILTGWESKNKYAIRNKNGQQCYYAFEE---SNAWERQCCGSQRGFTMHIVDNFNKNVLIVKRELRCCADSFC--GCLLGLQNICTIESLSTGLLGTVLQGYGCTNSFYNILDKDGNLIFLVDGQGCCTSCCCEDKDFTIKTPDSSVP------------------------------IGSITKKW-GGLLREAFTDADTFAVTFPIDLDVKLKAILLGATFLIDFVEFE 262
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Fly
Match: scramb1 (gene:FBgn0052056 transcript:FBtr0076302)

HSP 1 Score: 93.2041 bits (230), Expect = 6.670e-22
Identity = 72/250 (28.80%), Postives = 112/250 (44.80%), Query Frame = 3 
Query:  159 RSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            R LE L  +  + V+Q++  +L E   G    N + + +  G  +    E    N+CC+R  CGPAR F M  +DN ++ ++HM R P  C + C   C  C   I +S    N +G  +Q+ S C+P+  I++   + V  I GP C      D+ FNV +  G+                                 GKI K+W+      I  D +   +  P D+D   +A+LLG+ FL+D M+FE
Sbjct:   12 RGLEYLTTIDQLLVKQKV--ELLEAFTGFETNNKFTIKNALGQKVYFAAED---NDCCTRNCCGPARPFDMRVFDNFQQEVIHMHR-PLACSS-CLFPC--CLQSIEVSAPPGNVIGTIEQEWSICSPSFRILNHVGDTVMRIEGPFCTFSLCGDVEFNVVSLTGE-------------------------------KIGKISKQWSGLAR-EIFTDADFFGINFPLDLDVRMKAVLLGATFLIDAMFFE 220
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Fly
Match: scramb1 (gene:FBgn0052056 transcript:FBtr0076303)

HSP 1 Score: 92.8189 bits (229), Expect = 3.577e-21
Identity = 72/250 (28.80%), Postives = 112/250 (44.80%), Query Frame = 3 
Query:  159 RSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            R LE L  +  + V+Q++  +L E   G    N + + +  G  +    E    N+CC+R  CGPAR F M  +DN ++ ++HM R P  C + C   C  C   I +S    N +G  +Q+ S C+P+  I++   + V  I GP C      D+ FNV +  G+                                 GKI K+W+      I  D +   +  P D+D   +A+LLG+ FL+D M+FE
Sbjct:  111 RGLEYLTTIDQLLVKQKV--ELLEAFTGFETNNKFTIKNALGQKVYFAAED---NDCCTRNCCGPARPFDMRVFDNFQQEVIHMHR-PLACSS-CLFPC--CLQSIEVSAPPGNVIGTIEQEWSICSPSFRILNHVGDTVMRIEGPFCTFSLCGDVEFNVVSLTGE-------------------------------KIGKISKQWS-GLAREIFTDADFFGINFPLDLDVRMKAVLLGATFLIDAMFFE 319
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Fly
Match: scramb1 (gene:FBgn0052056 transcript:FBtr0076301)

HSP 1 Score: 93.5893 bits (231), Expect = 4.480e-21
Identity = 74/250 (29.60%), Postives = 113/250 (45.20%), Query Frame = 3 
Query:  159 RSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            R LE L  +  + V+Q++  +L E   G    N + + +  G  +    E    N+CC+R  CGPAR F M  +DN ++ ++HM R P  C + C   C  C   I +S    N +G  +Q+ S C+P+  I++   + V  I GP C      D+ FNV                     S+T  K            GKI K+W+      I  D +   +  P D+D   +A+LLG+ FL+D M+FE
Sbjct:  195 RGLEYLTTIDQLLVKQKV--ELLEAFTGFETNNKFTIKNALGQKVYFAAED---NDCCTRNCCGPARPFDMRVFDNFQQEVIHMHR-PLACSS-CLFPC--CLQSIEVSAPPGNVIGTIEQEWSICSPSFRILNHVGDTVMRIEGPFCTFSLCGDVEFNVV--------------------SLTGEK-----------IGKISKQWSGLAR-EIFTDADFFGINFPLDLDVRMKAVLLGATFLIDAMFFE 403
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Fly
Match: scramb2 (gene:FBgn0035390 transcript:FBtr0073005)

HSP 1 Score: 87.8113 bits (216), Expect = 1.024e-19
Identity = 63/250 (25.20%), Postives = 107/250 (42.80%), Query Frame = 3 
Query:  159 RSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            + LE L  L  + V Q++ +   E   G    N +KV +  G  +    E+ DC   C+R   G +R F M   DN +  ++H+ R P +CD  CC     C + + +S      +G  +Q C+   P  +I ++  + V  I GP CPC+C  D  F V + + +                                 GKI K+W+      +  D +   +  P ++D   +AL+  ++FL+D +Y+E
Sbjct:   53 QGLEYLTALDQLLVSQKIEK--LELLTGFETKNRFKVKNSLGQNVYFAYEESDC---CTRNMLGRSRPFEMKILDNFQNEVLHLYR-PFKCDILCCFPS--CMNAVEVSAPPGQVIGSVEQVCTFMRPKFNIKNTCGDTVLQIEGPVCPCKCFSDTNFKVLSANNEE-------------------------------IGKISKQWS-GLGRELFTDADYFSVTFPLNLDVRMKALIFAALFLIDAVYYE 262
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Zebrafish
Match: plscr3a (phospholipid scramblase 3a [Source:ZFIN;Acc:ZDB-GENE-060531-17])

HSP 1 Score: 96.6709 bits (239), Expect = 3.895e-23
Identity = 72/255 (28.24%), Postives = 107/255 (41.96%), Query Frame = 3 
Query:  144 PVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            P      LE L  +  + V Q++  +L E   G    N Y++ +  G  I    E  DC   C+R  CGP R F +   DN  + ++H+ R P RC + CC  C  C   + +     N +G+ KQ      P  S+ D +   + TI GP C   C  D+ F+V   DG                                  G+I K+W       +  D +N  +  P D+D   +A+LLG+ FL+DFM+FE
Sbjct:    8 PAAVPPGLEYLTQIDQILVHQKI--ELLEAIIGFETNNQYEIKNSMGQKIFHAKENTDC---CTRNICGPLRSFEIEIRDNFEQEVIHLSR-PYRCTS-CCFPC--CLQELEVQAPPGNPIGYIKQDWHMFKPMFSLYDMSKTKMLTIEGPLCAVSCCGDVDFDVLGKDGNP-------------------------------VGRISKQWAGLIKESLT-DSDNFGINFPIDLDVKMKAVLLGACFLIDFMFFE 221
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Zebrafish
Match: plscr3b (phospholipid scramblase 3b [Source:ZFIN;Acc:ZDB-GENE-040426-2517])

HSP 1 Score: 93.9745 bits (232), Expect = 1.543e-21
Identity = 75/256 (29.30%), Postives = 110/256 (42.97%), Query Frame = 3 
Query:  144 PVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDA-WCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            P      LE L  +  + + Q++  +L E   G    N Y++ +  G  I    EK   N+CC+R  CG  R F M   DN  R ++ + R P RC + WC   C  C   + I       +G+ KQ    C P  SI+    E V  + GPC  C C  D+ F +   DG G  +                             G+I K+WT      +  D +N  ++ P DMD   +A+L+G+ FL+DFM+FE
Sbjct:   86 PAGVPPGLEYLTQIDQILIHQKV--ELLEAFIGFETNNQYEIKNSLGQKIYSAKEK---NDCCTRNCCGALRSFDMKIKDNMDREVIRLIR-PYRCVSCWC--PC--CLQEMEIQAPPGTPIGYVKQDWHPCYPKFSIMGPNKETVMKLEGPCMACNCCGDVHFELKGKDGTGKPI-----------------------------GRISKQWT-GLLKEVFTDADNFGIQFPLDMDVKMKAVLMGTCFLIDFMFFE 301
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Zebrafish
Match: plscr3b (phospholipid scramblase 3b [Source:ZFIN;Acc:ZDB-GENE-040426-2517])

HSP 1 Score: 93.9745 bits (232), Expect = 1.543e-21
Identity = 75/256 (29.30%), Postives = 110/256 (42.97%), Query Frame = 3 
Query:  144 PVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDA-WCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            P      LE L  +  + + Q++  +L E   G    N Y++ +  G  I    EK   N+CC+R  CG  R F M   DN  R ++ + R P RC + WC   C  C   + I       +G+ KQ    C P  SI+    E V  + GPC  C C  D+ F +   DG G  +                             G+I K+WT      +  D +N  ++ P DMD   +A+L+G+ FL+DFM+FE
Sbjct:   86 PAGVPPGLEYLTQIDQILIHQKV--ELLEAFIGFETNNQYEIKNSLGQKIYSAKEK---NDCCTRNCCGALRSFDMKIKDNMDREVIRLIR-PYRCVSCWC--PC--CLQEMEIQAPPGTPIGYVKQDWHPCYPKFSIMGPNKETVMKLEGPCMACNCCGDVHFELKGKDGTGKPI-----------------------------GRISKQWT-GLLKEVFTDADNFGIQFPLDMDVKMKAVLMGTCFLIDFMFFE 301
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Zebrafish
Match: si:ch211-71m22.1 (si:ch211-71m22.1 [Source:ZFIN;Acc:ZDB-GENE-070705-193])

HSP 1 Score: 92.4337 bits (228), Expect = 2.525e-21
Identity = 78/274 (28.47%), Postives = 116/274 (42.34%), Query Frame = 3 
Query:   99 SNSKVDSEGQIVDPP----PVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
              + +   GQ+V  P    P      LE L  +  + VQQ++  +L E   G    N Y V +  G  +  + E+   N+CC+R +CGP R F +   DN  + +M + R P +C +  C  C  C   + I       +G+  Q      P  +I +   E V  I GP C CRC  D+ F+V + D                    S K            GKI K+WT         D +N  +  P D+D   +A+L G+ FL+DFM+FE
Sbjct:   27 QGAAIPGHGQVVMMPVPQRPDGCPPGLEYLTQIDQLLVQQKV--ELAEVILGWETNNKYIVKNSMGQQVFYVAEE---NDCCNRQFCGPLRSFVIHVQDNLGQEVMRLMR-PLKCGS--CF-CPCCLQELEIQSPPGYPIGYVIQNWHPFLPKFTIQNEKKEAVLKIEGPFCSCRCCSDVNFDVLSLD-------------------ESTK-----------VGKISKQWTGLVREAFT-DADNFGISFPMDLDVKIKAVLFGACFLIDFMFFE 260
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Zebrafish
Match: si:ch211-71m22.1 (si:ch211-71m22.1 [Source:ZFIN;Acc:ZDB-GENE-070705-193])

HSP 1 Score: 91.6633 bits (226), Expect = 2.620e-21
Identity = 73/249 (29.32%), Postives = 108/249 (43.37%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  + VQQ++  +L E   G    N Y V +  G  +  + E+   N+CC+R +CGP R F +   DN  + +M + R P +C +  C  C  C   + I       +G+  Q      P  +I +   E V  I GP C CRC  D+ F+V + D                    S K            GKI K+WT         D +N  +  P D+D   +A+L G+ FL+DFM+FE
Sbjct:   14 GLEYLTQIDQLLVQQKV--ELAEVILGWETNNKYIVKNSMGQQVFYVAEE---NDCCNRQFCGPLRSFVIHVQDNLGQEVMRLMR-PLKCGS--CF-CPCCLQELEIQSPPGYPIGYVIQNWHPFLPKFTIQNEKKEAVLKIEGPFCSCRCCSDVNFDVLSLD-------------------ESTK-----------VGKISKQWTGLVREAFT-DADNFGISFPMDLDVKIKAVLFGACFLIDFMFFE 222
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Xenopus
Match: insyn1 (inhibitory synaptic factor 1 [Source:Xenbase;Acc:XB-GENE-5931898])

HSP 1 Score: 111.694 bits (278), Expect = 8.951e-28
Identity = 78/251 (31.08%), Postives = 117/251 (46.61%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
             LE L  +  + V QQ+  +L E   G    N Y++ +  G  +    E+   N+CC+R  CGP+R F M   DN  + +M + R PCRC A CC  C  C  ++ +       +G+  Q    C P  +I D  ++ +  I+GPC PCRC  D+ F + + D                         ES V      G+I K+WT         D +N  ++ P D+D   +A+LLG+ FL+DFM+FE S
Sbjct:  105 GLEYLTQIDQILVHQQV--ELLEVLTGFETNNKYEIKNSLGQRVYFAAEE---NDCCTRNCCGPSRPFSMTIVDNAGQEVMKLHR-PCRCSA-CCFPC--CLQKLEVQAPPGTTVGYVIQNWHPCLPKFTIQDEREQGILKIKGPCIPCRCCADVKFEIKSMD-------------------------ESAV-----VGRITKQWTGFVKEAFT-DADNFGIQFPMDLDVKIKAVLLGACFLIDFMFFEQS 315
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Xenopus
Match: insyn1 (inhibitory synaptic factor 1 [Source:Xenbase;Acc:XB-GENE-5931898])

HSP 1 Score: 111.694 bits (278), Expect = 9.779e-28
Identity = 78/251 (31.08%), Postives = 117/251 (46.61%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
             LE L  +  + V QQ+  +L E   G    N Y++ +  G  +    E+   N+CC+R  CGP+R F M   DN  + +M + R PCRC A CC  C  C  ++ +       +G+  Q    C P  +I D  ++ +  I+GPC PCRC  D+ F + + D                         ES V      G+I K+WT         D +N  ++ P D+D   +A+LLG+ FL+DFM+FE S
Sbjct:  110 GLEYLTQIDQILVHQQV--ELLEVLTGFETNNKYEIKNSLGQRVYFAAEE---NDCCTRNCCGPSRPFSMTIVDNAGQEVMKLHR-PCRCSA-CCFPC--CLQKLEVQAPPGTTVGYVIQNWHPCLPKFTIQDEREQGILKIKGPCIPCRCCADVKFEIKSMD-------------------------ESAV-----VGRITKQWTGFVKEAFT-DADNFGIQFPMDLDVKIKAVLLGACFLIDFMFFEQS 320
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Xenopus
Match: ENSXETT00000012543.1 (phospholipid scramblase 2 [Source:NCBI gene;Acc:100489273])

HSP 1 Score: 105.145 bits (261), Expect = 1.100e-25
Identity = 76/248 (30.65%), Postives = 112/248 (45.16%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYF 893
             LE L  +  + V QQ+  +L E   G    N Y++ +  G  +    E+   N+CC+R +CGP+R F M   DN  R +M + R P RC A CC  C  C  ++ +       +G+  Q    C P  +I D  ++ V  I GPC PCRC  D+ F V + D                         ES V      G+I K+W  S    I  D +N  ++ P D+D   +A+LLG+ FL+   +F
Sbjct:   70 GLEYLSQIDQILVHQQV--ELLEVLTGFETNNKYEIKNSLGQRVYFAAEE---NDCCTRNYCGPSRPFAMTIVDNTGREVMKLHR-PLRCSA-CCFPC--CLQKLEVQAPPGTVVGYVVQNWHPCLPKFTIQDEREQGVLKISGPCIPCRCCTDVNFEVMSVD-------------------------ESSV-----VGRISKQWAGSVK-EIFTDTDNFGIQFPMDLDIKTKAVLLGACFLIVSSFF 277
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Xenopus
Match: ENSXETT00000046474.1 (uncharacterized LOC100497953 [Source:NCBI gene;Acc:100497953])

HSP 1 Score: 55.8398 bits (133), Expect = 4.042e-8
Identity = 43/168 (25.60%), Postives = 75/168 (44.64%), Query Frame = 3 
Query:  156 SRSLEVLDGLQNVRVQQQMPRDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVV 659
            S  L++L G Q   +  +       C    SY +   +   +L  +E    ++C     CGPAR   +   D ++  ++   R P R D  CCL C  C   I++     N +G  +Q+ S  +P++++ D+    +  I+G     RC  D  F V + DG+  +V+
Sbjct:  204 SAELQILSGAQQFCITSKSKPQGLSCHPERSYVISTRSSKQLLVAIED---SSCLCLHLCGPARSCSLRLCDYSKEEVLRFCR-PYRVDM-CCLFC--CLMVISVFSSSGNLIGSVQQRWSLFSPSLAVYDAYGRKIMEIKGSWSATRCHTDQEFQVTSLDGQLLAVI 364
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Mouse
Match: Plscr1 (phospholipid scramblase 1 [Source:MGI Symbol;Acc:MGI:893575])

HSP 1 Score: 87.8113 bits (216), Expect = 3.110e-19
Identity = 71/249 (28.51%), Postives = 108/249 (43.37%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  + V QQ+  +L E   G    N Y++ +  G  +   +E  DC   C+R  CG +R F +   DN  R +M + R P RC + CC  C  C   I I       +G+  Q    C P  ++ +   + V  + GPC  C C  D+ F + + D                         ES V      GKI K+W+         D +N  ++ P D+D   +A++LG+ FL+DFM+FE
Sbjct:  107 GLEYLAQIDQLLVHQQI--ELLEVLTGFETNNKYEIKNSLGQRVYFAVEDTDC---CTRNCCGASRPFTLRILDNLGREVMTLER-PLRCSS-CCFPC--CLQEIEIQAPPGVPVGYVTQTWHPCLPKFTLQNEKKQDVLKVVGPCVVCSCCSDIDFELKSLD------------------------EESVV------GKISKQWSGFVREAFT-DADNFGIQFPLDLDVKMKAVMLGACFLIDFMFFE 315
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Mouse
Match: Plscr1 (phospholipid scramblase 1 [Source:MGI Symbol;Acc:MGI:893575])

HSP 1 Score: 87.8113 bits (216), Expect = 3.110e-19
Identity = 71/249 (28.51%), Postives = 108/249 (43.37%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  + V QQ+  +L E   G    N Y++ +  G  +   +E  DC   C+R  CG +R F +   DN  R +M + R P RC + CC  C  C   I I       +G+  Q    C P  ++ +   + V  + GPC  C C  D+ F + + D                         ES V      GKI K+W+         D +N  ++ P D+D   +A++LG+ FL+DFM+FE
Sbjct:  107 GLEYLAQIDQLLVHQQI--ELLEVLTGFETNNKYEIKNSLGQRVYFAVEDTDC---CTRNCCGASRPFTLRILDNLGREVMTLER-PLRCSS-CCFPC--CLQEIEIQAPPGVPVGYVTQTWHPCLPKFTLQNEKKQDVLKVVGPCVVCSCCSDIDFELKSLD------------------------EESVV------GKISKQWSGFVREAFT-DADNFGIQFPLDLDVKMKAVMLGACFLIDFMFFE 315
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Mouse
Match: Plscr2 (phospholipid scramblase 2 [Source:MGI Symbol;Acc:MGI:1270860])

HSP 1 Score: 78.5666 bits (192), Expect = 4.004e-16
Identity = 66/258 (25.58%), Postives = 115/258 (44.57%), Query Frame = 3 
Query:  138 PPPVYY-SRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            PPP+      LE L+ +  + + QQ+  +L E   G    N +++ +  G  +   +E  DC   C+R  C  +R F +   D+  + +M + R P +C + CC  C  C   I I       +G+  Q    C P +++ +   E V  + GPC  C C  D+ F + + D     V +   IT Q                  +SG +++ +T         D +N  ++ P D++   +A+ LG+ FL+D+M+FE
Sbjct:   87 PPPILNCPPGLEYLNQIDQLLIHQQV--ELLEVLTGFETNNKFEIKNSLGQMVYVAVEDTDC---CTRNCCEASRPFTLRILDHLGQEVMTLER-PLKCSS-CCFPC--CLQEIEIQAPPGVPIGYVTQTWHPCLPKLTLQNDKRENVLKVVGPCVACTCCSDIDFEIKSLD----EVTRIGKITKQ------------------WSGCVKEAFT---------DSDNFGIQFPLDLEVKMKAVTLGACFLIDYMFFE 304
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Mouse
Match: Plscr2 (phospholipid scramblase 2 [Source:MGI Symbol;Acc:MGI:1270860])

HSP 1 Score: 78.5666 bits (192), Expect = 4.004e-16
Identity = 66/258 (25.58%), Postives = 115/258 (44.57%), Query Frame = 3 
Query:  138 PPPVYY-SRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            PPP+      LE L+ +  + + QQ+  +L E   G    N +++ +  G  +   +E  DC   C+R  C  +R F +   D+  + +M + R P +C + CC  C  C   I I       +G+  Q    C P +++ +   E V  + GPC  C C  D+ F + + D     V +   IT Q                  +SG +++ +T         D +N  ++ P D++   +A+ LG+ FL+D+M+FE
Sbjct:   87 PPPILNCPPGLEYLNQIDQLLIHQQV--ELLEVLTGFETNNKFEIKNSLGQMVYVAVEDTDC---CTRNCCEASRPFTLRILDHLGQEVMTLER-PLKCSS-CCFPC--CLQEIEIQAPPGVPIGYVTQTWHPCLPKLTLQNDKRENVLKVVGPCVACTCCSDIDFEIKSLD----EVTRIGKITKQ------------------WSGCVKEAFT---------DSDNFGIQFPLDLEVKMKAVTLGACFLIDYMFFE 304
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Mouse
Match: Plscr3 (phospholipid scramblase 3 [Source:MGI Symbol;Acc:MGI:1917560])

HSP 1 Score: 75.8702 bits (185), Expect = 3.899e-15
Identity = 67/249 (26.91%), Postives = 102/249 (40.96%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLK----ECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  + + Q+  R       E C  N Y++    G  + +  E+   +NCC+R  CG  R FR+   D   R ++ + R P  C   CC  C      +    G    +G   Q      P  SI+D+  +PV  + GPC  C C  D  F V T D                         ES        G+I K+W       +  D ++  ++ P D+D   +A+LLG+ FL+D+M+FE
Sbjct:   76 GLEFLVQIDQILIHQKAERVETFLGWETC--NMYELRSGTGQQLGQAAEE---SNCCARLCCGARRPFRIRLADPGDREVLRLLR-PLHCGCSCC-PCGLQEMEVQAPPG--TTIGHVLQTWHPFLPKFSILDADRQPVLRVVGPCWTCGCGTDTNFEVKTKD-------------------------ES-----RSVGRISKQWGGLLREALT-DADDFGLQFPVDLDVKVKAVLLGATFLIDYMFFE 284
[Close]
BLAST of Phospholipid scramblase vs. UniProt/SwissProt
Match: sp|Q3ZBG9|PLS2_BOVIN (Phospholipid scramblase 2 OS=Bos taurus OX=9913 GN=PLSCR2 PE=2 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 1.272e-22
Identity = 78/258 (30.23%), Postives = 112/258 (43.41%), Query Frame = 3 
Query:  141 PPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
            PP+     LE L  +  + + QQ+  +L E   G    N Y++ +  G  I    E  DC   C+R  CGP+R F M   DN  R ++ + R P RC + CC  C  C   I I       +G+  Q    C P  +I +   E V  I GPC  C C  D+ F V + D K                              Y  GKI K WT      +  D +N  ++ P D+D   +A++LG+ FL+DFM+FE++
Sbjct:   73 PPLNCPPGLEYLTQIDQLLIHQQI--ELLEVLIGFETNNKYEIKNSLGQRIYFAAEDTDC---CTRNCCGPSRPFTMRILDNMGREVITLER-PLRCTS-CCFPC--CLQEIEIQAPPGVPVGYVTQTWHPCLPKFTIQNERREDVLRISGPCVICSCCADIDFEVKSLDDK------------------------------YVVGKISKHWT-GLIKELFTDVDNFGIQFPLDLDVKMKAVMLGACFLIDFMFFEMT 290
[Close]
BLAST of Phospholipid scramblase vs. UniProt/SwissProt
Match: sp|Q9JJ00|PLS1_MOUSE (Phospholipid scramblase 1 OS=Mus musculus OX=10090 GN=Plscr1 PE=1 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 2.176e-18
Identity = 71/249 (28.51%), Postives = 108/249 (43.37%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  + V QQ+  +L E   G    N Y++ +  G  +   +E  DC   C+R  CG +R F +   DN  R +M + R P RC + CC  C  C   I I       +G+  Q    C P  ++ +   + V  + GPC  C C  D+ F + + D                         ES V      GKI K+W+         D +N  ++ P D+D   +A++LG+ FL+DFM+FE
Sbjct:  107 GLEYLAQIDQLLVHQQI--ELLEVLTGFETNNKYEIKNSLGQRVYFAVEDTDC---CTRNCCGASRPFTLRILDNLGREVMTLER-PLRCSS-CCFPC--CLQEIEIQAPPGVPVGYVTQTWHPCLPKFTLQNEKKQDVLKVVGPCVVCSCCSDIDFELKSLD------------------------EESVV------GKISKQWSGFVREAFT-DADNFGIQFPLDLDVKMKAVMLGACFLIDFMFFE 315
[Close]
BLAST of Phospholipid scramblase vs. UniProt/SwissProt
Match: sp|P58195|PLS1_RAT (Phospholipid scramblase 1 OS=Rattus norvegicus OX=10116 GN=Plscr1 PE=1 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 3.548e-18
Identity = 71/249 (28.51%), Postives = 108/249 (43.37%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  + V QQ+  +L E   G    N Y++ +  G  +   +E  DC   C+R  CG +R F +   DN  R +M + R P RC + CC  C  C   I I       +G+  Q    C P  ++ +   + V  + GPC  C C  D+ F + + D                         ES V      GKI K+W+         D +N  ++ P D+D   +A++LG+ FL+DFM+FE
Sbjct:  115 GLEYLTQIDQILVHQQI--ELLEVLTGFETNNKYEIKNSLGQRVYFAVEDTDC---CTRNCCGASRPFTLRILDNMGREVMTLER-PLRCSS-CCFPC--CLQEIEIQAPPGVPVGYVIQTWHPCLPKFTLQNEKRQDVLKVVGPCVVCSCCSDIDFELKSLD------------------------EESVV------GKISKQWSGFVREAFT-DADNFGIQFPLDLDVKMKAVMLGACFLIDFMFFE 323
[Close]
BLAST of Phospholipid scramblase vs. UniProt/SwissProt
Match: sp|Q9DCW2|PLS2_MOUSE (Phospholipid scramblase 2 OS=Mus musculus OX=10090 GN=Plscr2 PE=1 SV=3)

HSP 1 Score: 78.5666 bits (192), Expect = 2.800e-15
Identity = 66/258 (25.58%), Postives = 115/258 (44.57%), Query Frame = 3 
Query:  138 PPPVYY-SRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            PPP+      LE L+ +  + + QQ+  +L E   G    N +++ +  G  +   +E  DC   C+R  C  +R F +   D+  + +M + R P +C + CC  C  C   I I       +G+  Q    C P +++ +   E V  + GPC  C C  D+ F + + D     V +   IT Q                  +SG +++ +T         D +N  ++ P D++   +A+ LG+ FL+D+M+FE
Sbjct:   87 PPPILNCPPGLEYLNQIDQLLIHQQV--ELLEVLTGFETNNKFEIKNSLGQMVYVAVEDTDC---CTRNCCEASRPFTLRILDHLGQEVMTLER-PLKCSS-CCFPC--CLQEIEIQAPPGVPIGYVTQTWHPCLPKLTLQNDKRENVLKVVGPCVACTCCSDIDFEIKSLD----EVTRIGKITKQ------------------WSGCVKEAFT---------DSDNFGIQFPLDLEVKMKAVTLGACFLIDYMFFE 304
[Close]
BLAST of Phospholipid scramblase vs. UniProt/SwissProt
Match: sp|Q6QBQ4|PLS3_RAT (Phospholipid scramblase 3 OS=Rattus norvegicus OX=10116 GN=Plscr3 PE=2 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 5.521e-15
Identity = 65/249 (26.10%), Postives = 100/249 (40.16%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLK----ECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  + + Q+  R       E C  N Y++    G  + +  E+   +NCC+R  CG  R  R+   D   R ++ + R P  C   CC  C      +    G    +G   Q      P  SI+D+  +PV  + GPCC C C  D  F V T D                                   G+I K+W       +  D ++  ++ P D+D   +A+LLG+ FL+D+M+FE
Sbjct:   76 GLEFLVQIDQILIHQKAERVETFLGWETC--NRYELRSGTGQQLGQAAEE---SNCCARLCCGARRPLRIRLADPGDREVLRLLR-PLHCGCSCC-PCGLQEMEVQAPPG--TTIGHVLQTWHPFIPKFSILDADRQPVLRVVGPCCTCGCGTDTNFEVKTKD------------------------------ESRSVGRISKQWGGLLREALT-DADDFGLQFPVDLDVRVKAVLLGATFLIDYMFFE 284
[Close]
BLAST of Phospholipid scramblase vs. TrEMBL
Match: A0A1X7VVQ2 (Phospholipid scramblase OS=Amphimedon queenslandica OX=400682 GN=100640566 PE=3 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 6.151e-29
Identity = 78/249 (31.33%), Postives = 115/249 (46.18%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  + V QQ+  +L E   G    N YKV +  G  +    E    +NCC R +CGP+R F M   DNN+R ++H+ R P RC +WCC  C+     + +       +GF +Q CS   P  S+ ++  E V  I+GP CPC+C  D+ F V + DG                                  GKI K+W+         D +N  +  P D+D   +A++L + FL+DFM+FE
Sbjct:   24 GLEYLTQVDQLLVNQQI--ELLEIMTGFETQNKYKVRNSLGQQVYFAAED---SNCCLRQYCGPSRPFGMQILDNNQREVIHLER-PLRCSSWCCFCCL---QTMEVQSPPGTVIGFVEQDCSLVYPWFSLKNADGETVLKIKGPLCPCKCCYDVEFQVLSADGT------------------------------QEVGKISKKWSGLAKEYFT-DADNFGVTFPMDLDVKMKAVMLAATFLIDFMFFE 232
[Close]
BLAST of Phospholipid scramblase vs. TrEMBL
Match: K1R4F4 (Phospholipid scramblase OS=Crassostrea gigas OX=29159 GN=CGI_10011097 PE=3 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 6.062e-27
Identity = 73/225 (32.44%), Postives = 103/225 (45.78%), Query Frame = 3 
Query:  132 VDPPPVYYSRSLEVLDGLQNVRVQQQMPRDLKECC-HGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHE 803
            +DPPP      LE L G   V V+QQM  D++  C   N+YK+++E    +  +LE     +C  RW+CGP R F++  +      +  + R  CRCD  CCLDCV C+H++ + D     LG  KQK   C  N  ++D+  E V  I GPCC  RC  +LTF ++   G+                                 G I K+W       IN+DHE
Sbjct:   70 LDPPP-----GLEGLTGKGFVYVRQQMETDIRGGCGSANTYKIWNEKEEELFYVLED---TSCICRWFCGPHRQFQLEFFTPQDDLVFTLFRKSCRCDWCCCLDCVLCNHKVYVVDCLNRTLGSIKQKFGVCQGNFEVLDNDGEIVAKIFGPCCVFRCCTELTFEIWDKIGEEK------------------------------LGSINKKWEGEQDTGINVDHE 256
[Close]
BLAST of Phospholipid scramblase vs. TrEMBL
Match: A0A1L8GAQ5 (Phospholipid scramblase OS=Xenopus laevis OX=8355 GN=XELAEV_18027735mg PE=3 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 7.729e-26
Identity = 80/250 (32.00%), Postives = 116/250 (46.40%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEV 899
             LE L  +  + V QQ+  +L E   G    N Y++ +  G  +    E+   N+CC+R +CGP+R F M   DN  R ++ + R PCRC A CC  C  C  ++ +       +G+  Q    C P  +I D   + V  IRGPC PC C  D+ F V + D                         ES V      G I K+WT S    I  D +N  ++ P D+D   +A++LG+ FL+DFM+FE 
Sbjct:   90 GLEYLSQIDQILVHQQV--ELLEVLTGFETNNKYEIKNSMGQRVYFAAEE---NDCCTRNYCGPSRPFIMTIVDNTGREVIKLHR-PCRCSA-CCFPC--CLQKLEVQAPPGTVVGYIVQNWHPCLPKFTIQDERGQGVLKIRGPCIPCSCCADVNFEVKSMD-------------------------ESAV-----VGMISKQWTGSVK-EIFTDSDNFGIQFPMDLDIKTKAVMLGACFLIDFMFFET 299
[Close]
BLAST of Phospholipid scramblase vs. TrEMBL
Match: B3RTS4 (Phospholipid scramblase (Fragment) OS=Trichoplax adhaerens OX=10228 GN=TRIADDRAFT_15248 PE=3 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 7.788e-26
Identity = 77/246 (31.30%), Postives = 108/246 (43.90%), Query Frame = 3 
Query:  165 LEVLDGLQNVRVQQQMP--RDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            LE L  +  + + QQ+            N Y V +  G  +    E    N+CC+   CGPAR F +   DN++R ++H+ R P RC + CC  C      +T+     N +GF KQ  S   P   I D+    V TI GPCCPC C+ D+ F V + DG                                  GKI K+W+         D +N  +  P D+D   +A LLG++FL+DFMYFE
Sbjct:   52 LEYLTQIDQLLIHQQVEILELFTNIETANKYAVKNTLGQQVYFAAED---NDCCTLQCCGPARPFELRILDNSQREVIHLSR-PYRCSS-CCCPCFL--QELTVESPPGNTVGFVKQSWSLFTPAFDITDAAGNTVLTIEGPCCPCSCMGDVEFEVKSKDGA------------------------------TKVGKITKQWS-GLLKEAFTDADNFGITFPMDLDVKVKATLLGAVFLIDFMYFE 259
[Close]
BLAST of Phospholipid scramblase vs. TrEMBL
Match: A0A1L8G4F4 (Phospholipid scramblase OS=Xenopus laevis OX=8355 GN=XELAEV_18029827mg PE=3 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 9.274e-26
Identity = 83/254 (32.68%), Postives = 118/254 (46.46%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS*EK 911
             LE L  +  + V QQ+  +L E   G    N Y++ +  G  +    E+   N+CC+R  CGP R F M   DN  R IM + R PCRC + CC  C  C  ++ +       +G+ KQ    C P  +I D  ++ V  I+GPC PC C  D+ F V T D    SVV                            G+I K+WT         D +N  ++ P D+D   +A+LLG+ FL+DFM+FE S +K
Sbjct:  130 GLEYLSQIDQILVHQQV--ELLEALTGYETNNKYEIKNSLGQRVYFAAEE---NDCCTRNCCGPGRPFTMTIVDNTGREIMKLNR-PCRCSS-CCFPC--CLQKLEVQAPPGTVVGYVKQNWHPCLPKFTIQDENEQGVLKIKGPCIPCSCCTDVNFEVKTMDES--SVV----------------------------GRITKQWTGYVK-EAFTDADNFGIQFPMDLDVKVKAVLLGACFLIDFMFFEESEKK 343
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Cavefish
Match: si:ch211-71m22.5 (si:ch211-71m22.5 [Source:ZFIN;Acc:ZDB-GENE-130531-65])

HSP 1 Score: 92.0485 bits (227), Expect = 2.549e-21
Identity = 71/250 (28.40%), Postives = 108/250 (43.20%), Query Frame = 3 
Query:  165 LEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
            LE L  +  + + Q++  +L E   G    N Y V +  G  +    E+   N+ C+R  CGP R F +   DN  R ++ + R P  C + CC  C  C   + +       +G+  QK     P  +I D   + V  I GP C C C  D+ F V + DG   SV+                            G+I K+WT      +  D +N  ++ P D+D   +A++L + FL+DFMYFE S
Sbjct:   33 LEYLTQIDQILIHQKV--ELMEAMLGWETNNQYVVKNSLGQQVFLAAEE---NDFCTRTMCGPMRSFVLHLQDNTGREVLTLTR-PLNCSS-CCFPC--CLQELEVQSPPGQPIGYVIQKWHPYLPKFTIKDERKQSVMQIVGPFCDCNCCSDVNFEVMSLDGA--SVI----------------------------GRISKQWTGMEAEMLT-DADNFGVQFPMDLDVKIKAVILSACFLIDFMYFENS 242
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Cavefish
Match: plscr3b (phospholipid scramblase 2-like [Source:NCBI gene;Acc:103046260])

HSP 1 Score: 89.7373 bits (221), Expect = 5.920e-20
Identity = 73/249 (29.32%), Postives = 108/249 (43.37%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  V + Q++  +L E   G    N Y+V +  G  I +  EK   N+CC+R  CG  R F M   DN  R ++ + R P RC A C   C  C   + +       +G+  Q    C P  SI     E V  + GPC  C C  D+ F +   DG G S+                             G+I K+W+      +  D +N  ++ P DMD   +A+L+G+ FL+DF++FE
Sbjct:  104 GLEYLTQIDQVLIHQKV--ELLEAIIGFETNNQYEVKNSMGQKIYKAKEK---NDCCTRNCCGSLRSFDMKIKDNTDREVIRLIR-PFRC-ATCWCPC--CLQEMEVQAPPGTTIGYVTQDWHPCYPKFSIKGPNKETVMKLEGPCLACNCCGDVNFELKGKDG-GKSI-----------------------------GRISKQWS-GLLKEVFTDTDNFGIQFPLDMDVKMKAVLMGACFLIDFIFFE 312
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Cavefish
Match: plscr3b (phospholipid scramblase 2-like [Source:NCBI gene;Acc:103046260])

HSP 1 Score: 89.7373 bits (221), Expect = 5.920e-20
Identity = 73/249 (29.32%), Postives = 108/249 (43.37%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  V + Q++  +L E   G    N Y+V +  G  I +  EK   N+CC+R  CG  R F M   DN  R ++ + R P RC A C   C  C   + +       +G+  Q    C P  SI     E V  + GPC  C C  D+ F +   DG G S+                             G+I K+W+      +  D +N  ++ P DMD   +A+L+G+ FL+DF++FE
Sbjct:  104 GLEYLTQIDQVLIHQKV--ELLEAIIGFETNNQYEVKNSMGQKIYKAKEK---NDCCTRNCCGSLRSFDMKIKDNTDREVIRLIR-PFRC-ATCWCPC--CLQEMEVQAPPGTTIGYVTQDWHPCYPKFSIKGPNKETVMKLEGPCLACNCCGDVNFELKGKDG-GKSI-----------------------------GRISKQWS-GLLKEVFTDTDNFGIQFPLDMDVKMKAVLMGACFLIDFIFFE 312
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Cavefish
Match: si:ch73-206p6.1 (phospholipid scramblase 1 [Source:NCBI gene;Acc:103028162])

HSP 1 Score: 84.7297 bits (208), Expect = 8.475e-19
Identity = 66/253 (26.09%), Postives = 112/253 (44.27%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVF--CSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
             LE L  +  + ++Q++  +L E   G    N Y++ +  G  +   +E+   N+C +R  CGP R F +   DN  + ++ + R P +C     + C F  C   + +     N +G+  Q+     P  +I +   EPV  ++GP C   CL D+ F + T D        D +I                       GKI K+WT         D +N  ++ P D+D   +A+++G  FL+DFM+FE +
Sbjct:   19 GLEYLTQVDQLLIKQKV--ELIEALAGFESNNKYEIRNAMGQNVFYAVEE---NDCLTRQCCGPLRSFTIRVLDNFGQEVITVNR-PLKC-----MSCFFPCCLQELEVQSPPGNIVGYVLQEWHPFLPKFTIKNEHREPVLKLQGPFCGWSCLPDVDFEIMTMD--------DVSI-----------------------GKISKQWTGLLREAFT-DADNFGIQFPMDLDVRMKAVMIGLCFLIDFMFFETN 228
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Cavefish
Match: si:ch211-71m22.1 (phospholipid scramblase 1-like [Source:NCBI gene;Acc:103030773])

HSP 1 Score: 82.0333 bits (201), Expect = 1.231e-17
Identity = 73/257 (28.40%), Postives = 113/257 (43.97%), Query Frame = 3 
Query:  144 PVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
            PV     LE L  +  + V Q++  +L E   G    N Y V +  G  +  + E+   N+CC+R  CGP R F +   DN  + +M + R P RC + CC  C+     + +     N +G+  QK     P   + +   E V  I+GP C C C  D+ F V + D                      +S +         G+I K+WT         D +N  ++ P D+D   +A+L G++FL+DFM+FE S
Sbjct:   45 PVGCPPGLEYLTQIDQLLVHQKI--ELAEVILGWETNNKYLVKNTLGQQVFYVAEE---NDCCTRQCCGPMRSFVLHVQDNMGQEVMTLTR-PLRCASCCCPCCL---QELEVQAPPGNPIGYVIQKWHPFLPKFIVQNEKREDVLRIQGPFCACNCCSDVNFEVMSMD----------------------ESTQ--------VGRICKQWTGMLQEAFT-DADNFGIKFPMDLDVKIKAVLFGALFLIDFMFFENS 261
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Nematostella
Match: EDO31512 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXP9])

HSP 1 Score: 105.145 bits (261), Expect = 8.127e-27
Identity = 74/248 (29.84%), Postives = 112/248 (45.16%), Query Frame = 3 
Query:  165 LEVLDGLQNVRVQQQMP--RDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
            LE L  +  + ++QQ+        C   N Y++ +  G  +    E  DC   C+R  CGPAR F M   DN  R ++H+ R P RC  +CC  C+     I +     N +G+ +Q+   C P  +I D+  + + T+ GP C CRC  D+ F V + DG  P                               GK+ K+WT         D EN  +  P D+D   +A++LG++FL+DFM+FE  
Sbjct:   14 LEYLTQIDQLLIRQQVELFELFTGCEMKNKYQITNSLGQQVYFAKEDTDC---CTRQCCGPARPFEMEITDNTGREVIHLSR-PLRCACFCCWCCL---QTIEVQAPRGNVVGYVEQEFYICKPKFTIKDANRQTILTMTGPICACRCCADVEFPVLSADGTVP------------------------------VGKVTKQWT-GLIKEAFTDAENFGITFPMDLDVKMKAVMLGAVFLIDFMFFETQ 223
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Nematostella
Match: EDO46109 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR56])

HSP 1 Score: 80.8777 bits (198), Expect = 9.062e-17
Identity = 61/242 (25.21%), Postives = 102/242 (42.15%), Query Frame = 3 
Query:  165 LEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLV 878
            LE L  +  + ++QQ+  +L E   G    N YK+ +  G  +    E  DC   C+R  CGP+R F +   DN +R ++H+ R P RC + C   C  C   + +       +G+  Q  S C P  ++ D+  + +  I GP C      D+ F V + DG+                                 GK+ K+W+         D +N  +  P D+D   +A+++G+ FL+
Sbjct:   87 LEYLTMVDQLLIKQQV--ELLEAFTGFETNNKYKITNNLGQQVFFAAEDTDC---CTRQCCGPSRPFDIKIMDNTQREVIHLTR-PLRCSS-CWFPC--CLQEVEVQSPPGTVVGYCCQSWSICIPKYTLQDANRQTILQIEGPLCTFNICGDVEFQVLSADGQNQ------------------------------VGKVSKQWS-GLVKEAFTDADNFGVTFPMDLDVKMKAVIIGTAFLI 288
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Medaka
Match: si:ch73-206p6.1 (phospholipid scramblase 1 [Source:NCBI gene;Acc:101170797])

HSP 1 Score: 83.9593 bits (206), Expect = 1.965e-18
Identity = 59/220 (26.82%), Postives = 95/220 (43.18%), Query Frame = 3 
Query:  243 NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
            N Y++ +  G  +   +E+   N+C SR  CGP R F +   DN  + I+ + R P +C + C   C  C   + +     N +G+  Q+     P   + +  +EPV  I GP C   CL D+ F + T D                                   GKI K+WT         D +N  ++ P D+D   +A+++G+ FL+DFM+FE +
Sbjct:   63 NKYEIRNVMGQNVFYAVEE---NDCLSRQCCGPLRSFTIHVLDNFGQEIITVTR-PLKCMS-CFFPC--CLQELEVQSPPGNTVGYVIQQWHPFFPKFIVANEHNEPVLKIHGPFCGWSCLPDVDFEILTMDEVNK------------------------------IGKISKQWTGLLREAFT-DSDNFGIQFPLDLDVRMKAVMIGACFLIDFMFFETT 244
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Medaka
Match: si:ch73-206p6.1 (phospholipid scramblase 1 [Source:NCBI gene;Acc:101170797])

HSP 1 Score: 83.9593 bits (206), Expect = 1.965e-18
Identity = 59/220 (26.82%), Postives = 95/220 (43.18%), Query Frame = 3 
Query:  243 NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
            N Y++ +  G  +   +E+   N+C SR  CGP R F +   DN  + I+ + R P +C + C   C  C   + +     N +G+  Q+     P   + +  +EPV  I GP C   CL D+ F + T D                                   GKI K+WT         D +N  ++ P D+D   +A+++G+ FL+DFM+FE +
Sbjct:   63 NKYEIRNVMGQNVFYAVEE---NDCLSRQCCGPLRSFTIHVLDNFGQEIITVTR-PLKCMS-CFFPC--CLQELEVQSPPGNTVGYVIQQWHPFFPKFIVANEHNEPVLKIHGPFCGWSCLPDVDFEILTMDEVNK------------------------------IGKISKQWTGLLREAFT-DSDNFGIQFPLDLDVRMKAVMIGACFLIDFMFFETT 244
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Medaka
Match: plscr3b (phospholipid scramblase 2 [Source:NCBI gene;Acc:101157328])

HSP 1 Score: 75.8702 bits (185), Expect = 2.350e-15
Identity = 68/255 (26.67%), Postives = 111/255 (43.53%), Query Frame = 3 
Query:  144 PVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            P+     LE L  +  + + Q++  +L E   G    N Y++ +  G  I    EK   N+CC+R  CG  R F M   DN  R ++ + R P RC + CC  C+     + +       +G+ KQ      P  SI  +  E +  + GPC  C C  D++F +    GK  + +                            G+I K+W+      +  D +N  ++ P D+D   +A+L+G+ FL+DFM+FE
Sbjct:   64 PIGIPPGLEYLAQIDQILIHQKV--ELLEAFIGFETNNQYEIKNNLGQKIYTAKEK---NDCCTRNCCGALRSFDMKIKDNTDREVIRLIR-PFRCVSCCCPCCL---QEMEVQAPPGTTVGYVKQDWHPFLPKFSIQGANKETLMRLEGPCFACNCCGDVSFEL---KGKDETPI----------------------------GRITKQWS-GLLKEVFTDTDNFGIQFPLDLDVKMKAVLMGACFLIDFMFFE 277
[Close]
BLAST of Phospholipid scramblase vs. Ensembl Medaka
Match: plscr3b (phospholipid scramblase 2 [Source:NCBI gene;Acc:101157328])

HSP 1 Score: 75.8702 bits (185), Expect = 2.350e-15
Identity = 68/255 (26.67%), Postives = 111/255 (43.53%), Query Frame = 3 
Query:  144 PVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            P+     LE L  +  + + Q++  +L E   G    N Y++ +  G  I    EK   N+CC+R  CG  R F M   DN  R ++ + R P RC + CC  C+     + +       +G+ KQ      P  SI  +  E +  + GPC  C C  D++F +    GK  + +                            G+I K+W+      +  D +N  ++ P D+D   +A+L+G+ FL+DFM+FE
Sbjct:   64 PIGIPPGLEYLAQIDQILIHQKV--ELLEAFIGFETNNQYEIKNNLGQKIYTAKEK---NDCCTRNCCGALRSFDMKIKDNTDREVIRLIR-PFRCVSCCCPCCL---QEMEVQAPPGTTVGYVKQDWHPFLPKFSIQGANKETLMRLEGPCFACNCCGDVSFEL---KGKDETPI----------------------------GRITKQWS-GLLKEVFTDTDNFGIQFPLDLDVKMKAVLMGACFLIDFMFFE 277
[Close]
BLAST of Phospholipid scramblase vs. Planmine SMEST
Match: SMESG000016647.1 (SMESG000016647.1)

HSP 1 Score: 565.459 bits (1456), Expect = 0.000e+0
Identity = 271/271 (100.00%), Postives = 271/271 (100.00%), Query Frame = 3 
Query:   90 MGVSNSKVDSEGQIVDPPPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 902
            MGVSNSKVDSEGQIVDPPPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS
Sbjct:    1 MGVSNSKVDSEGQIVDPPPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFEVS 271
[Close]
BLAST of Phospholipid scramblase vs. Planmine SMEST
Match: SMESG000050656.1 (SMESG000050656.1)

HSP 1 Score: 81.2629 bits (199), Expect = 1.813e-17
Identity = 68/250 (27.20%), Postives = 108/250 (43.20%), Query Frame = 3 
Query:  162 SLEVLDGLQNVRVQQ--QMPRDLKECCHGNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRHPCRCDAWC-CLDCVFCSH-RITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGP-CCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
             LE L  +  + V+Q   +     E    N Y V +  G ++    E+   N CC R+WCG  R F +  YDN+ + +M +RR P +C     C +C  CS   + +       +G+ KQ    C    +I+D     +  + GP  C C C  D                 D+ +    G MT+    E         GKI K+W+      +    +N  ++ P D+D   +A++L ++FL+DFMYFE
Sbjct:   31 GLEYLTQINQLLVKQLFDLIEVFTEYDTNNKYLVNNILGQSVFYAKEE---NGCCMRYWCGSNRSFVIYVYDNSNQVVMEIRR-PLKCHYMGPCCNCSKCSRDELEVQAPPGEVIGYVKQLYEGCQVRYAILDKDKNIILRLHGPHYCFCYCPGD-----------------DYPV----GVMTANGDLEI--------GKITKQWSGWA-QELYTTADNFGVQFPMDLDVKYKAIVLAAVFLIDFMYFE 246
[Close]
BLAST of Phospholipid scramblase vs. Planmine SMEST
Match: SMESG000043802.1 (SMESG000043802.1)

HSP 1 Score: 79.337 bits (194), Expect = 3.286e-16
Identity = 72/267 (26.97%), Postives = 111/267 (41.57%), Query Frame = 3 
Query:  126 QIVDPPPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRH---PCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCR---CLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            Q+V  PP      LE L  +  + V QQ+  +L E        N Y++ +  G  +    E+ D    C+R  CGP RGF M   DN    ++   R           CC     C+  +T+       +G   Q+ SC  P+ +I ++ +E +  IRGP C C+   C  D  F VF+ D                   T L             G+I K+W+   +     D +N  +  P D+D   +A +L ++FL+DFM+FE
Sbjct:  176 QVVGCPP-----GLEYLTMVDQILVHQQI--ELLEVFTNWETKNKYQIKNSLGQQVYYAAEESDV---CARQCCGPQRGFVMHITDNMGTEVIRAMREFKCCAGPCCHCCAGIDMCAQELTVEAPPGQAIGRVIQQSSCLEPSYAIQNADEETMLQIRGPICICQGPCCTWDQEFKVFSSD-----------------MSTEL-------------GRISKQWSGFVHEYFT-DADNFGVSFPIDLDVKMKATMLAAVFLIDFMFFE 401
[Close]
BLAST of Phospholipid scramblase vs. Planmine SMEST
Match: SMESG000043802.1 (SMESG000043802.1)

HSP 1 Score: 78.9518 bits (193), Expect = 4.113e-16
Identity = 72/267 (26.97%), Postives = 111/267 (41.57%), Query Frame = 3 
Query:  126 QIVDPPPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRH---PCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCR---CLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            Q+V  PP      LE L  +  + V QQ+  +L E        N Y++ +  G  +    E+ D    C+R  CGP RGF M   DN    ++   R           CC     C+  +T+       +G   Q+ SC  P+ +I ++ +E +  IRGP C C+   C  D  F VF+ D                   T L             G+I K+W+   +     D +N  +  P D+D   +A +L ++FL+DFM+FE
Sbjct:  187 QVVGCPP-----GLEYLTMVDQILVHQQI--ELLEVFTNWETKNKYQIKNSLGQQVYYAAEESDV---CARQCCGPQRGFVMHITDNMGTEVIRAMREFKCCAGPCCHCCAGIDMCAQELTVEAPPGQAIGRVIQQSSCLEPSYAIQNADEETMLQIRGPICICQGPCCTWDQEFKVFSSDMS-----------------TEL-------------GRISKQWSGFVHEYFT-DADNFGVSFPIDLDVKMKATMLAAVFLIDFMFFE 412
[Close]
BLAST of Phospholipid scramblase vs. Planmine SMEST
Match: SMESG000043802.1 (SMESG000043802.1)

HSP 1 Score: 78.9518 bits (193), Expect = 4.163e-16
Identity = 72/267 (26.97%), Postives = 111/267 (41.57%), Query Frame = 3 
Query:  126 QIVDPPPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCHG----NSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPIMHMRRH---PCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNISIVDSTDEPVGTIRGPCCPCR---CLCDLTFNVFTPDGKGPSVVKDFAITDQPGSMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDTVERALLLGSMFLVDFMYFE 896
            Q+V  PP      LE L  +  + V QQ+  +L E        N Y++ +  G  +    E+ D    C+R  CGP RGF M   DN    ++   R           CC     C+  +T+       +G   Q+ SC  P+ +I ++ +E +  IRGP C C+   C  D  F VF+ D                   T L             G+I K+W+   +     D +N  +  P D+D   +A +L ++FL+DFM+FE
Sbjct:  190 QVVGCPP-----GLEYLTMVDQILVHQQI--ELLEVFTNWETKNKYQIKNSLGQQVYYAAEESDV---CARQCCGPQRGFVMHITDNMGTEVIRAMREFKCCAGPCCHCCAGIDMCAQELTVEAPPGQAIGRVIQQSSCLEPSYAIQNADEETMLQIRGPICICQGPCCTWDQEFKVFSSDMS-----------------TEL-------------GRISKQWSGFVHEYFT-DADNFGVSFPIDLDVKMKATMLAAVFLIDFMFFE 415
The following BLAST results are available for this feature:
BLAST of Phospholipid scramblase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PLSCR11.169e-1528.16phospholipid scramblase 1 [Source:HGNC Symbol;Acc:... [more]
PLSCR11.266e-1528.16phospholipid scramblase 1 [Source:HGNC Symbol;Acc:... [more]
PLSCR57.702e-1426.25phospholipid scramblase family member 5 [Source:HG... [more]
PLSCR57.702e-1426.25phospholipid scramblase family member 5 [Source:HG... [more]
PLSCR12.597e-1326.86phospholipid scramblase 1 [Source:HGNC Symbol;Acc:... [more]
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BLAST of Phospholipid scramblase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
scrm-13.286e-1426.25Phospholipid scramblase [Source:UniProtKB/TrEMBL;... [more]
scrm-13.286e-1426.25Phospholipid scramblase [Source:UniProtKB/TrEMBL;... [more]
scrm-13.941e-1426.25Phospholipid scramblase [Source:UniProtKB/TrEMBL;... [more]
scrm-13.951e-1426.25Phospholipid scramblase [Source:UniProtKB/TrEMBL;... [more]
scrm-21.345e-1126.19Phospholipid scramblase [Source:UniProtKB/TrEMBL;... [more]
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BLAST of Phospholipid scramblase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
scramb16.670e-2228.80gene:FBgn0052056 transcript:FBtr0076302[more]
scramb13.577e-2128.80gene:FBgn0052056 transcript:FBtr0076303[more]
scramb14.480e-2129.60gene:FBgn0052056 transcript:FBtr0076301[more]
scramb21.024e-1925.20gene:FBgn0035390 transcript:FBtr0073005[more]
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BLAST of Phospholipid scramblase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plscr3a3.895e-2328.24phospholipid scramblase 3a [Source:ZFIN;Acc:ZDB-GE... [more]
plscr3b1.543e-2129.30phospholipid scramblase 3b [Source:ZFIN;Acc:ZDB-GE... [more]
plscr3b1.543e-2129.30phospholipid scramblase 3b [Source:ZFIN;Acc:ZDB-GE... [more]
si:ch211-71m22.12.525e-2128.47si:ch211-71m22.1 [Source:ZFIN;Acc:ZDB-GENE-070705-... [more]
si:ch211-71m22.12.620e-2129.32si:ch211-71m22.1 [Source:ZFIN;Acc:ZDB-GENE-070705-... [more]
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BLAST of Phospholipid scramblase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
insyn18.951e-2831.08inhibitory synaptic factor 1 [Source:Xenbase;Acc:X... [more]
insyn19.779e-2831.08inhibitory synaptic factor 1 [Source:Xenbase;Acc:X... [more]
ENSXETT00000012543.11.100e-2530.65phospholipid scramblase 2 [Source:NCBI gene;Acc:10... [more]
ENSXETT00000046474.14.042e-825.60uncharacterized LOC100497953 [Source:NCBI gene;Acc... [more]
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BLAST of Phospholipid scramblase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Plscr13.110e-1928.51phospholipid scramblase 1 [Source:MGI Symbol;Acc:M... [more]
Plscr13.110e-1928.51phospholipid scramblase 1 [Source:MGI Symbol;Acc:M... [more]
Plscr24.004e-1625.58phospholipid scramblase 2 [Source:MGI Symbol;Acc:M... [more]
Plscr24.004e-1625.58phospholipid scramblase 2 [Source:MGI Symbol;Acc:M... [more]
Plscr33.899e-1526.91phospholipid scramblase 3 [Source:MGI Symbol;Acc:M... [more]
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BLAST of Phospholipid scramblase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q3ZBG9|PLS2_BOVIN1.272e-2230.23Phospholipid scramblase 2 OS=Bos taurus OX=9913 GN... [more]
sp|Q9JJ00|PLS1_MOUSE2.176e-1828.51Phospholipid scramblase 1 OS=Mus musculus OX=10090... [more]
sp|P58195|PLS1_RAT3.548e-1828.51Phospholipid scramblase 1 OS=Rattus norvegicus OX=... [more]
sp|Q9DCW2|PLS2_MOUSE2.800e-1525.58Phospholipid scramblase 2 OS=Mus musculus OX=10090... [more]
sp|Q6QBQ4|PLS3_RAT5.521e-1526.10Phospholipid scramblase 3 OS=Rattus norvegicus OX=... [more]
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BLAST of Phospholipid scramblase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1X7VVQ26.151e-2931.33Phospholipid scramblase OS=Amphimedon queenslandic... [more]
K1R4F46.062e-2732.44Phospholipid scramblase OS=Crassostrea gigas OX=29... [more]
A0A1L8GAQ57.729e-2632.00Phospholipid scramblase OS=Xenopus laevis OX=8355 ... [more]
B3RTS47.788e-2631.30Phospholipid scramblase (Fragment) OS=Trichoplax a... [more]
A0A1L8G4F49.274e-2632.68Phospholipid scramblase OS=Xenopus laevis OX=8355 ... [more]
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BLAST of Phospholipid scramblase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch211-71m22.52.549e-2128.40si:ch211-71m22.5 [Source:ZFIN;Acc:ZDB-GENE-130531-... [more]
plscr3b5.920e-2029.32phospholipid scramblase 2-like [Source:NCBI gene;A... [more]
plscr3b5.920e-2029.32phospholipid scramblase 2-like [Source:NCBI gene;A... [more]
si:ch73-206p6.18.475e-1926.09phospholipid scramblase 1 [Source:NCBI gene;Acc:10... [more]
si:ch211-71m22.11.231e-1728.40phospholipid scramblase 1-like [Source:NCBI gene;A... [more]
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BLAST of Phospholipid scramblase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Phospholipid scramblase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Phospholipid scramblase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO315128.127e-2729.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO461099.062e-1725.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Phospholipid scramblase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
si:ch73-206p6.11.965e-1826.82phospholipid scramblase 1 [Source:NCBI gene;Acc:10... [more]
si:ch73-206p6.11.965e-1826.82phospholipid scramblase 1 [Source:NCBI gene;Acc:10... [more]
plscr3b2.350e-1526.67phospholipid scramblase 2 [Source:NCBI gene;Acc:10... [more]
plscr3b2.350e-1526.67phospholipid scramblase 2 [Source:NCBI gene;Acc:10... [more]
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BLAST of Phospholipid scramblase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000016647.10.000e+0100.00SMESG000016647.1[more]
SMESG000050656.11.813e-1727.20SMESG000050656.1[more]
SMESG000043802.13.286e-1626.97SMESG000043802.1[more]
SMESG000043802.14.113e-1626.97SMESG000043802.1[more]
SMESG000043802.14.163e-1626.97SMESG000043802.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30022020 ID=SMED30022020|Name=Phospholipid scramblase|organism=Schmidtea mediterranea sexual|type=transcript|length=1005bp
CTAGTATCTATTTCTATCTTTGAGTTTATCAGTTTGATATAGAAGTTATA
GAAGTTATTGTGGGTCAAGATTTTGCAGGACTTTAAAATATGGGTGTTTC
CAATTCAAAAGTTGACTCTGAAGGTCAAATTGTGGATCCACCACCGGTTT
ATTATTCGCGAAGCTTAGAAGTTTTAGATGGGTTGCAAAATGTAAGAGTA
CAACAGCAAATGCCGAGAGATTTGAAGGAATGTTGTCATGGAAATTCTTA
CAAAGTCTTTGATGAGAATGGAAATACCATTTTGAGAATTCTCGAAAAGC
CAGATTGTAACAATTGTTGTAGTCGATGGTGGTGTGGTCCAGCAAGAGGA
TTTAGAATGGTAGCTTATGATAATAATCGTCGACCAATCATGCATATGAG
ACGACATCCTTGCAGATGTGATGCATGGTGTTGTTTAGATTGTGTGTTTT
GCTCTCATAGAATAACAATTTCCGATGGCGATAAAAATTATTTGGGATTT
GGAAAACAGAAATGTTCATGTTGTGCTCCAAATATTTCAATCGTCGATTC
TACAGATGAGCCTGTAGGCACTATCAGAGGTCCCTGTTGCCCATGTCGAT
GTCTATGCGATTTGACATTTAATGTATTTACTCCAGATGGGAAAGGTCCA
TCTGTAGTTAAAGATTTCGCTATCACTGACCAACCGGGCAGTATGACGTC
TTTAAAATCAGCCGAAAGTTATGTGGAGAACTTTTATTATTCGGGTAAAA
TTGAAAAGAGGTGGACTAAATCAACATATCCTAGAATCAACATGGATCAT
GAAAATATAATGATGAGAATTCCAGACGATATGGACACGGTTGAGCGAGC
TCTTTTGTTGGGATCTATGTTTTTAGTGGATTTTATGTACTTCGAAGTTT
CATAAGAAAAAATTACAATGAAAATCCAATATAAACTTTATTTTAAGAGT
AAAGATATTGAAAAATTTTACGGAATTGTTATTTTTGTTTAGATTTGTTG
TGAGA
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protein sequence of SMED30022020-orf-1

>SMED30022020-orf-1 ID=SMED30022020-orf-1|Name=SMED30022020-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=272bp
MGVSNSKVDSEGQIVDPPPVYYSRSLEVLDGLQNVRVQQQMPRDLKECCH
GNSYKVFDENGNTILRILEKPDCNNCCSRWWCGPARGFRMVAYDNNRRPI
MHMRRHPCRCDAWCCLDCVFCSHRITISDGDKNYLGFGKQKCSCCAPNIS
IVDSTDEPVGTIRGPCCPCRCLCDLTFNVFTPDGKGPSVVKDFAITDQPG
SMTSLKSAESYVENFYYSGKIEKRWTKSTYPRINMDHENIMMRIPDDMDT
VERALLLGSMFLVDFMYFEVS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000418head
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR005552Scramblase
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0017121phospholipid scrambling
Vocabulary: molecular function
TermDefinition
GO:0017128phospholipid scramblase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR005552ScramblasePFAMPF03803Scramblasecoord: 26..269
e-value: 2.3E-28
score: 99.0
IPR005552ScramblasePANTHERPTHR23248PHOSPHOLIPID SCRAMBLASE-RELATEDcoord: 21..269