RING finger protein

Overview
NameRING finger protein
Smed IDSMED30021994
Length (bp)2013
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RING finger protein (SMED30021994) t-SNE clustered cells

Violin plots show distribution of expression levels for RING finger protein (SMED30021994) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RING finger protein (SMED30021994) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RING finger protein (SMED30021994) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30021994

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30021994SMESG000016827.1 dd_Smed_v4_3878_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30021994SMESG000016827.1 dd_Smed_v4_3878_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of RING finger protein vs. Ensembl Human
Match: RNF10 (ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055])

HSP 1 Score: 77.7962 bits (190), Expect = 5.865e-16
Identity = 51/184 (27.72%), Postives = 86/184 (46.74%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP----INLNEARIPYVYSNE--SRFSNTAVCSNED-FQTLIQIDIMALEDELCNAIAEESDNINA--ITAALEATRNELE 998
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K     +P    +N++    P    +E  S++S   + S E     ++  + +ALE +L    AEE     +  I AA++  +  LE
Sbjct:    2 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDH---PIHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQL----AEEKHTPESCFIEAAIQELKGVLE 178
[Close]
BLAST of RING finger protein vs. Ensembl Human
Match: RNF10 (ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055])

HSP 1 Score: 74.7146 bits (182), Expect = 3.753e-13
Identity = 51/182 (28.02%), Postives = 84/182 (46.15%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP----INLNEARIPYVYSNESRFSNTAVCSNED-FQTLIQIDIMALEDELCNAIAEESDNINA--ITAALE--ATRNE 992
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K     +P    +N++   I       S++S   + S E     ++  + +ALE +L    AEE     +  I AA++   TR E
Sbjct:  204 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHP-IHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQL----AEEKHTPESCFIEAAIQELKTREE 380

HSP 2 Score: 64.6994 bits (156), Expect = 3.812e-10
Identity = 30/101 (29.70%), Postives = 59/101 (58.42%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+    +  P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:  513 FYQAEDGQHMFLHPVNVRCLVREYGSLERS-PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 612
[Close]
BLAST of RING finger protein vs. Ensembl Human
Match: RNF10 (ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055])

HSP 1 Score: 74.3294 bits (181), Expect = 3.904e-13
Identity = 51/182 (28.02%), Postives = 84/182 (46.15%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP----INLNEARIPYVYSNESRFSNTAVCSNED-FQTLIQIDIMALEDELCNAIAEESDNINA--ITAALE--ATRNE 992
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K     +P    +N++   I       S++S   + S E     ++  + +ALE +L    AEE     +  I AA++   TR E
Sbjct:  204 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHP-IHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQL----AEEKHTPESCFIEAAIQELKTREE 380

HSP 2 Score: 64.6994 bits (156), Expect = 4.072e-10
Identity = 30/101 (29.70%), Postives = 59/101 (58.42%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+    +  P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:  508 FYQAEDGQHMFLHPVNVRCLVREYGSLERS-PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 607
[Close]
BLAST of RING finger protein vs. Ensembl Human
Match: RNF10 (ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055])

HSP 1 Score: 64.6994 bits (156), Expect = 8.923e-11
Identity = 31/103 (30.10%), Postives = 62/103 (60.19%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEF--LDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+  L+++   P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:   44 FYQAEDGQHMFLHPVNVRCLVREYGSLERS---PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 143
[Close]
BLAST of RING finger protein vs. Ensembl Human
Match: RNF10 (ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055])

HSP 1 Score: 60.4622 bits (145), Expect = 9.770e-10
Identity = 30/109 (27.52%), Postives = 62/109 (56.88%), Query Frame = 3 
Query: 1080 MKTDNVYYQSEDGSNIFMCPLNWKCMSFEF--LDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            + +   YY  +DG ++F+ P+N +C+  E+  L+++   P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:   46 LSSSPCYYFYQDGQHMFLHPVNVRCLVREYGSLERS---PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 151
[Close]
BLAST of RING finger protein vs. Ensembl Fly
Match: CG12099 (gene:FBgn0035232 transcript:FBtr0072829)

HSP 1 Score: 112.464 bits (280), Expect = 1.814e-25
Identity = 92/352 (26.14%), Postives = 154/352 (43.75%), Query Frame = 3 
Query:  402 EEYIHATSQIWLNQKCLKSEYDFDDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKS----DSFPVPINLNEARIPYVYSNES--RFSNTAVCSNEDFQTLIQI---DIMALEDELC-------NAIAEESDNINAITAALEATRNELELS----CLLP----DVSKPXXXXXXXXXXXXXXXXMKTDNVY---YQSEDGSNIFMCPLNWKCMS--FEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEI 1367
            E+++ A  Q  +            D    W  I QIN   TE++ CPIC+  P  ++  +CGH YC+PCL  +LS  +  ++KC +C   I    +K     +   L VG+ I+  LMRR K     ++    +     R P+V + E   R+S   +    D   +I+    +++A  D  C        A+    + +  +       + + E +    CL      D+ K    + SS E     S     N Y   YQS DG NI++ PLN K +   +  LD     PL I  +I+++E+  +  +   ++  L +LP+    S VE+ L   +++   L+ FK +I
Sbjct:  167 EQFLQANFQFVIRSGAKAQVNGSPDALIDWSYIEQINIQTTEELQCPICLYPPVAAKLTRCGHAYCWPCLLHYLSLSDKTWRKCPICYDAIHAGDLKSCTIEQLRDLQVGEKITFQLMRRRKGSMYIENHVAGLGETIERFPFVSAGEEAKRYSKFLIAKRMDVAAIIERERNELLAESDVSCPEDVFIQQALVMLQERVEKLGVEKPDPKEDEEETAPVLCLETETKIDIEKSDDASISSGEASSSLSYSSNHNKYYYFYQSNDGQNIYLHPLNVKMLQACYGTLDLG---PLLIEAQIVQMEQHSMDEEHRRKFTCLGHLPLTCQFSVVEVELQPPVVTGGILKLFKEDI 515
[Close]
BLAST of RING finger protein vs. Ensembl Fly
Match: CG12099 (gene:FBgn0035232 transcript:FBtr0072828)

HSP 1 Score: 112.464 bits (280), Expect = 1.814e-25
Identity = 92/352 (26.14%), Postives = 154/352 (43.75%), Query Frame = 3 
Query:  402 EEYIHATSQIWLNQKCLKSEYDFDDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKS----DSFPVPINLNEARIPYVYSNES--RFSNTAVCSNEDFQTLIQI---DIMALEDELC-------NAIAEESDNINAITAALEATRNELELS----CLLP----DVSKPXXXXXXXXXXXXXXXXMKTDNVY---YQSEDGSNIFMCPLNWKCMS--FEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEI 1367
            E+++ A  Q  +            D    W  I QIN   TE++ CPIC+  P  ++  +CGH YC+PCL  +LS  +  ++KC +C   I    +K     +   L VG+ I+  LMRR K     ++    +     R P+V + E   R+S   +    D   +I+    +++A  D  C        A+    + +  +       + + E +    CL      D+ K    + SS E     S     N Y   YQS DG NI++ PLN K +   +  LD     PL I  +I+++E+  +  +   ++  L +LP+    S VE+ L   +++   L+ FK +I
Sbjct:  167 EQFLQANFQFVIRSGAKAQVNGSPDALIDWSYIEQINIQTTEELQCPICLYPPVAAKLTRCGHAYCWPCLLHYLSLSDKTWRKCPICYDAIHAGDLKSCTIEQLRDLQVGEKITFQLMRRRKGSMYIENHVAGLGETIERFPFVSAGEEAKRYSKFLIAKRMDVAAIIERERNELLAESDVSCPEDVFIQQALVMLQERVEKLGVEKPDPKEDEEETAPVLCLETETKIDIEKSDDASISSGEASSSLSYSSNHNKYYYFYQSNDGQNIYLHPLNVKMLQACYGTLDLG---PLLIEAQIVQMEQHSMDEEHRRKFTCLGHLPLTCQFSVVEVELQPPVVTGGILKLFKEDI 515
[Close]
BLAST of RING finger protein vs. Ensembl Fly
Match: CG43058 (gene:FBgn0262360 transcript:FBtr0304641)

HSP 1 Score: 45.8246 bits (107), Expect = 6.862e-6
Identity = 24/59 (40.68%), Postives = 36/59 (61.02%), Query Frame = 3 
Query:  525 EDIMCPICMDAPKVSR--TDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKR 695
            E  MCPICM+  +  +     CGHV+C+ C+ K +    G YKKC +CN++I  K++ R
Sbjct:   43 EPYMCPICMENVRRRQPAATPCGHVFCYDCIQKAI----GDYKKCPMCNKKIMYKQLTR 97
[Close]
BLAST of RING finger protein vs. Ensembl Zebrafish
Match: rnf10 (ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-2969])

HSP 1 Score: 80.4925 bits (197), Expect = 2.919e-15
Identity = 48/173 (27.75%), Postives = 82/173 (47.40%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP----INLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINA--ITAAL 974
            D    WD + Q+  Y  E   CPIC+  P  +   +CGH+YC+PC+  +LS     + KC +C + +    +K    +E      G++I++ LMRR K     +P    + + E  I +       +S   + S +    L+  + MAL+ +L    ++E D+  A  I +AL
Sbjct:  201 DTLVDWDCVQQVRIYSHEVPSCPICLYPPVAAHMTRCGHIYCWPCMLHYLSLSEKSWSKCPICYEAVHSADLKSVVAMETRQYVSGNSITMCLMRREKGSLVALPSSQWVKVEEP-IQFGDVQFCSYSKLLLASRQQVLGLLAEERMALQTQL----SQEKDDPQACFIQSAL 368

HSP 2 Score: 63.929 bits (154), Expect = 4.217e-10
Identity = 32/101 (31.68%), Postives = 57/101 (56.44%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG  +F+ P+N +C+  ++       P  IT  ++EI+   +T D   R+RYL +LP+    S  E++L   I+S  TL  F ++I+++   R  +
Sbjct:  482 FYQAEDGQQMFLHPVNVRCLQRQYGSLENS-PQTITANVVEIDGQTVTEDIRRRHRYLSHLPLTCEFSLCELDLQPPILSKETLDSFADDIEKRKRLRQKK 581
[Close]
BLAST of RING finger protein vs. Ensembl Zebrafish
Match: rnf10 (ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-2969])

HSP 1 Score: 70.0922 bits (170), Expect = 5.835e-12
Identity = 44/160 (27.50%), Postives = 76/160 (47.50%), Query Frame = 3 
Query:  513 FYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP----INLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINA--ITAAL 974
             Y  E   CPIC+  P  +   +CGH+YC+PC+  +LS     + KC +C + +    +K    +E      G++I++ LMRR K     +P    + + E  I +       +S   + S +    L+  + MAL+ +L    ++E D+  A  I +AL
Sbjct:  243 IYSHEVPSCPICLYPPVAAHMTRCGHIYCWPCMLHYLSLSEKSWSKCPICYEAVHSADLKSVVAMETRQYVSGNSITMCLMRREKGSLVALPSSQWVKVEEP-IQFGDVQFCSYSKLLLASRQQVLGLLAEERMALQTQL----SQEKDDPQACFIQSAL 397

HSP 2 Score: 63.929 bits (154), Expect = 4.440e-10
Identity = 32/101 (31.68%), Postives = 57/101 (56.44%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG  +F+ P+N +C+  ++       P  IT  ++EI+   +T D   R+RYL +LP+    S  E++L   I+S  TL  F ++I+++   R  +
Sbjct:  511 FYQAEDGQQMFLHPVNVRCLQRQYGSLENS-PQTITANVVEIDGQTVTEDIRRRHRYLSHLPLTCEFSLCELDLQPPILSKETLDSFADDIEKRKRLRQKK 610
[Close]
BLAST of RING finger protein vs. Ensembl Xenopus
Match: egfl7 (EGF like domain multiple 7 [Source:Xenbase;Acc:XB-GENE-491413])

HSP 1 Score: 75.0998 bits (183), Expect = 2.396e-13
Identity = 31/99 (31.31%), Postives = 51/99 (51.52%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKS 770
            D    WD + Q+  +  E   CPIC+  P  ++  +CGH++C+ C+  +LS     + +C +C   +  K +K     E    +VGD I++ LMRR K 
Sbjct:  184 DTLVSWDFVEQVRIFSHEVPSCPICLYPPVAAKITRCGHIFCWACILHYLSLSEKDWSRCPICYSSVIKKDLKSVVTTETHLYSVGDKITMQLMRREKG 282

HSP 2 Score: 62.3882 bits (150), Expect = 2.149e-9
Identity = 30/101 (29.70%), Postives = 58/101 (57.43%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLSNI-ISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+ DG ++++ P+N +C+  E+    +C P +IT  ++E++ F +T +   R+RYL +LP+    S  E+ L    +S  TL  F  E++++   R  +
Sbjct:  466 FYQAVDGQHVYLHPVNVRCLVHEYGSLERC-PEKITATVVEMDGFTMTEEVRRRHRYLCHLPLTCEFSICEMALGPPDVSVDTLELFTAEVEKRKRLRQRK 565
[Close]
BLAST of RING finger protein vs. Ensembl Xenopus
Match: egfl7 (EGF like domain multiple 7 [Source:Xenbase;Acc:XB-GENE-491413])

HSP 1 Score: 74.7146 bits (182), Expect = 2.685e-13
Identity = 32/105 (30.48%), Postives = 53/105 (50.48%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP 788
            D    WD + Q+  +  E   CPIC+  P  ++  +CGH++C+ C+  +LS     + +C +C   +  K +K     E    +VGD I++ LMRR K     +P
Sbjct:  184 DTLVSWDFVEQVRIFSHEVPSCPICLYPPVAAKITRCGHIFCWACILHYLSLSEKDWSRCPICYSSVIKKDLKSVVTTETHLYSVGDKITMQLMRREKGVLVAMP 288

HSP 2 Score: 62.3882 bits (150), Expect = 2.080e-9
Identity = 30/101 (29.70%), Postives = 58/101 (57.43%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLSNI-ISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+ DG ++++ P+N +C+  E+    +C P +IT  ++E++ F +T +   R+RYL +LP+    S  E+ L    +S  TL  F  E++++   R  +
Sbjct:  466 FYQAVDGQHVYLHPVNVRCLVHEYGSLERC-PEKITATVVEMDGFTMTEEVRRRHRYLCHLPLTCEFSICEMALGPPDVSVDTLELFTAEVEKRKRLRQRK 565
[Close]
BLAST of RING finger protein vs. Ensembl Mouse
Match: Rnf10 (ring finger protein 10 [Source:MGI Symbol;Acc:MGI:1859162])

HSP 1 Score: 74.7146 bits (182), Expect = 1.928e-13
Identity = 44/160 (27.50%), Postives = 73/160 (45.62%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKS--DSFPV--------PINLNEARIPYVYSNESRFSNTAVCSNED-FQTLIQIDIMALEDEL 920
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K    + P         PINL + ++       S++S   + S E     ++  +  ALE +L
Sbjct:  167 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESRQYAVGDTITMQLMKREKGVLVALPKSKWVNVDHPINLGDEQL-------SQYSKLLLASKEQVLHRVVLEEKGALEQQL 319

HSP 2 Score: 66.6254 bits (161), Expect = 7.193e-11
Identity = 31/101 (30.69%), Postives = 59/101 (58.42%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+    Q  P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:  464 FYQAEDGQHMFLHPVNVRCLVREYGSLEQS-PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 563
[Close]
BLAST of RING finger protein vs. Ensembl Mouse
Match: Rnf10 (ring finger protein 10 [Source:MGI Symbol;Acc:MGI:1859162])

HSP 1 Score: 74.7146 bits (182), Expect = 2.302e-13
Identity = 49/183 (26.78%), Postives = 84/183 (45.90%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKS--DSFPV--------PINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINA--ITAALEATR 986
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K    + P         PINL + ++       S++S   + S E  Q L ++ ++  +  L   +AEE     +  I AA++  +
Sbjct:  204 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESRQYAVGDTITMQLMKREKGVLVALPKSKWVNVDHPINLGDEQL-------SQYSKLLLASKE--QVLHRV-VLEEKGALEQQLAEEKHTPESCFIEAAIQEVK 376

HSP 2 Score: 66.6254 bits (161), Expect = 7.937e-11
Identity = 31/101 (30.69%), Postives = 59/101 (58.42%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+    Q  P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:  501 FYQAEDGQHMFLHPVNVRCLVREYGSLEQS-PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 600
[Close]
BLAST of RING finger protein vs. Ensembl Mouse
Match: Rnf10 (ring finger protein 10 [Source:MGI Symbol;Acc:MGI:1859162])

HSP 1 Score: 74.7146 bits (182), Expect = 2.405e-13
Identity = 49/183 (26.78%), Postives = 84/183 (45.90%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKS--DSFPV--------PINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINA--ITAALEATR 986
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K    + P         PINL + ++       S++S   + S E  Q L ++ ++  +  L   +AEE     +  I AA++  +
Sbjct:  204 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESRQYAVGDTITMQLMKREKGVLVALPKSKWVNVDHPINLGDEQL-------SQYSKLLLASKE--QVLHRV-VLEEKGALEQQLAEEKHTPESCFIEAAIQEVK 376

HSP 2 Score: 66.6254 bits (161), Expect = 8.011e-11
Identity = 31/101 (30.69%), Postives = 59/101 (58.42%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+    Q  P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:  501 FYQAEDGQHMFLHPVNVRCLVREYGSLEQS-PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 600
[Close]
BLAST of RING finger protein vs. Ensembl Mouse
Match: Rnf10 (ring finger protein 10 [Source:MGI Symbol;Acc:MGI:1859162])

HSP 1 Score: 74.7146 bits (182), Expect = 2.428e-13
Identity = 49/183 (26.78%), Postives = 84/183 (45.90%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKS--DSFPV--------PINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINA--ITAALEATR 986
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K    + P         PINL + ++       S++S   + S E  Q L ++ ++  +  L   +AEE     +  I AA++  +
Sbjct:  204 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESRQYAVGDTITMQLMKREKGVLVALPKSKWVNVDHPINLGDEQL-------SQYSKLLLASKE--QVLHRV-VLEEKGALEQQLAEEKHTPESCFIEAAIQEVK 376

HSP 2 Score: 66.6254 bits (161), Expect = 7.879e-11
Identity = 31/101 (30.69%), Postives = 59/101 (58.42%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+    Q  P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:  502 FYQAEDGQHMFLHPVNVRCLVREYGSLEQS-PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 601
[Close]
BLAST of RING finger protein vs. UniProt/SwissProt
Match: sp|Q32NQ8|RNF10_XENLA (RING finger protein 10 OS=Xenopus laevis OX=8355 GN=rnf10 PE=2 SV=1)

HSP 1 Score: 79.7221 bits (195), Expect = 4.383e-14
Identity = 33/99 (33.33%), Postives = 52/99 (52.53%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKS 770
            D    WD + Q+  +  E   CPIC+  P  ++  +CGH++C+PC+  +LS     + +C +C   I  K +K     E    +VGD I++ LMRR K 
Sbjct:  185 DTLVSWDFVEQVRIFSHEVASCPICLYPPVAAKITRCGHIFCWPCILHYLSLSEKDWSRCPICYSSIIKKDLKSVVATETHLYSVGDKITMQLMRREKG 283

HSP 2 Score: 63.5438 bits (153), Expect = 3.994e-9
Identity = 31/101 (30.69%), Postives = 58/101 (57.43%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLSNI-ISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+ DG ++++ P+N +C+  E+    +C P +IT  ++E++ F +T +   R+RYL +LP+    S  EI L    +S  TL  F  E++++   R  +
Sbjct:  467 FYQAVDGQHVYLHPVNVRCLVHEYGSLERC-PEKITATVVEMDGFTMTEEVRRRHRYLCHLPLTCEFSICEIALGPPDVSVKTLELFTEEVEKRKRLRQRK 566
[Close]
BLAST of RING finger protein vs. UniProt/SwissProt
Match: sp|Q08E13|RNF10_BOVIN (RING finger protein 10 OS=Bos taurus OX=9913 GN=RNF10 PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 7.262e-13
Identity = 49/198 (24.75%), Postives = 83/198 (41.92%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP----INLNEARIPYVYSNESRFSNTAVCSNED-FQTLIQIDIMALEDELC-------------------------NAIAEESDNINAITAALE 977
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K     +P    +N++   I       S++S   + S E   + ++Q +  ALE +L                          + +AE    +  + AALE
Sbjct:  204 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESRQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHP-IHLGDEQHSQYSKLLLASKEQVLRRVVQEEKAALERQLAEEKHTPESCFIEAAIQELKAREEALSGLAESRGEVPGVVAALE 400

HSP 2 Score: 65.4698 bits (158), Expect = 1.053e-9
Identity = 31/101 (30.69%), Postives = 59/101 (58.42%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+    Q  P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:  507 FYQAEDGQHMFLHPVNVRCLVREYGSLEQS-PEKISATVVEISGYSMSEDMRQRHRYLSHLPLTCEFSICELALQPPLVSKETLEIFSDDIEKRKRQRQKK 606
[Close]
BLAST of RING finger protein vs. UniProt/SwissProt
Match: sp|Q3UIW5|RNF10_MOUSE (RING finger protein 10 OS=Mus musculus OX=10090 GN=Rnf10 PE=2 SV=2)

HSP 1 Score: 74.7146 bits (182), Expect = 1.682e-12
Identity = 49/183 (26.78%), Postives = 84/183 (45.90%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKS--DSFPV--------PINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINA--ITAALEATR 986
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K    + P         PINL + ++       S++S   + S E  Q L ++ ++  +  L   +AEE     +  I AA++  +
Sbjct:  204 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESRQYAVGDTITMQLMKREKGVLVALPKSKWVNVDHPINLGDEQL-------SQYSKLLLASKE--QVLHRV-VLEEKGALEQQLAEEKHTPESCFIEAAIQEVK 376

HSP 2 Score: 66.6254 bits (161), Expect = 5.603e-10
Identity = 31/101 (30.69%), Postives = 59/101 (58.42%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+    Q  P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:  501 FYQAEDGQHMFLHPVNVRCLVREYGSLEQS-PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 600
[Close]
BLAST of RING finger protein vs. UniProt/SwissProt
Match: sp|Q8N5U6|RNF10_HUMAN (RING finger protein 10 OS=Homo sapiens OX=9606 GN=RNF10 PE=1 SV=2)

HSP 1 Score: 74.3294 bits (181), Expect = 1.875e-12
Identity = 51/182 (28.02%), Postives = 84/182 (46.15%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP----INLNEARIPYVYSNESRFSNTAVCSNED-FQTLIQIDIMALEDELCNAIAEESDNINA--ITAALE--ATRNE 992
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K     +P    +N++   I       S++S   + S E     ++  + +ALE +L    AEE     +  I AA++   TR E
Sbjct:  204 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSEKTWSKCPICYSSVHKKDLKSVVATESHQYVVGDTITMQLMKREKGVLVALPKSKWMNVDHP-IHLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQL----AEEKHTPESCFIEAAIQELKTREE 380

HSP 2 Score: 64.6994 bits (156), Expect = 1.956e-9
Identity = 30/101 (29.70%), Postives = 59/101 (58.42%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+    +  P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:  508 FYQAEDGQHMFLHPVNVRCLVREYGSLERS-PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 607
[Close]
BLAST of RING finger protein vs. UniProt/SwissProt
Match: sp|Q5XI59|RNF10_RAT (RING finger protein 10 OS=Rattus norvegicus OX=10116 GN=Rnf10 PE=2 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 2.030e-12
Identity = 50/180 (27.78%), Postives = 84/180 (46.67%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP----INLNEARIPYVYSNE--SRFSNTAVCSNED-FQTLIQIDIMALEDELCNAIAEESDNINA--ITAALEATR 986
            D    WD + Q+     E   CPIC+  P  ++  +CGH++C+ C+  +LS     + KC +C   +  K +K     E     VGD I++ LM+R K     +P    +N++    P    +E  S++S   + S E     ++  + +ALE +L    AEE     +  I AAL+  +
Sbjct:  204 DTLVNWDFVEQVRICSHEVPSCPICLYPPTAAKITRCGHIFCWACILHYLSLSERTWSKCPICYSSVHKKDLKSVVATESRQYVVGDTITMQLMKREKGVLVALPKSKWMNVDH---PISLGDEQHSQYSKLLLASKEQVLHRVVLEEKVALEQQL----AEEKHTPESCFIEAALQEVK 376

HSP 2 Score: 66.6254 bits (161), Expect = 5.361e-10
Identity = 31/101 (30.69%), Postives = 59/101 (58.42%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+EDG ++F+ P+N +C+  E+    Q  P +I+  ++EI  + ++ D   R+RYL +LP+    S  E+ L   ++S  TL  F ++I+++   R  +
Sbjct:  500 FYQAEDGQHMFLHPVNVRCLVREYGSLEQS-PEKISATVVEIAGYSMSEDVRQRHRYLSHLPLTCEFSICELALQPPVVSKETLEMFSDDIEKRKRQRQKK 599
[Close]
BLAST of RING finger protein vs. TrEMBL
Match: A0A5K3FVE5 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 176.792 bits (447), Expect = 1.159e-43
Identity = 126/401 (31.42%), Postives = 201/401 (50.12%), Query Frame = 3 
Query:  399 NEE--YIHATSQIWLNQKC-LKSEYDFDDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYEN-GYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPV----PINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDEL--CNA---------IAEESDNINAITAALEATRNELELSCLLPDVSKPXXXXXXXXXXXXXXXXMKTDNVYYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYREQLDNVLTTEKIKHEN---SFNVASGFMCVTSLMNETKQILDDDFVPL 1532
            NEE  Y+ A  Q+ +N    L   +   D    W  ++++  Y+ EDI+CPIC+  P   R   CGH+YCFPC   F+ YEN    +KCA+C+  + +  +KR   I      VGD + L LMRR KS +FPV     +   E  +P         S  AV SN D ++++  DI  +E  L  C +         +AEE      I   L++ RN LE      DV     +   +  ++  ++ ++   +YY+   G+++++  +NW+C+  E+   N+ LP  I+GK++EIE   +  +   RYRYL +LP+G +   VEI+L   +IS  TL +    +  +   R  +++++ +LT  K++ EN   S  V    +   SL NE     D+DFVPL
Sbjct:   84 NEEFDYVTAHCQLLINPHTDLTQVFRDPDAAVAWCDVLEVRCYQVEDIICPICLYPPVSPRMGPCGHIYCFPCAWYFIKYENETLSQKCAVCSTYLRISELKRVRIISSTIPQVGDVVELQLMRRYKSVTFPVHSNNEVTDKENVLPTSELASHFRSRIAVASNHDLRSIVNRDIDDIEAYLLECRSDGLSDCMIPVAEE------ILCLLQSERNALE------DVEP---MTDHAYTLELTDAELEKYFIYYKEVSGNDMYLHSVNWRCLQIEY--GNEELPKAISGKVVEIESRTMNLELRQRYRYLSHLPLGRTFYLVEIDLGPPVISGKTLSEMSEALTMRQLRREEKKRVEKLLTLAKLEAENRIQSLPVGCRLVGHASLDNEVPT--DEDFVPL 465
[Close]
BLAST of RING finger protein vs. TrEMBL
Match: A0A0R3UAQ7 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS4006 PE=4 SV=1)

HSP 1 Score: 173.326 bits (438), Expect = 2.080e-42
Identity = 126/404 (31.19%), Postives = 203/404 (50.25%), Query Frame = 3 
Query:  399 NEE--YIHATSQIWLNQKC-LKSEYDFDDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYEN-GYYKKCALCNQEIDLKRVKRAAFIERFS---LNVGDNISLLLMRRSKSDSFPV----PINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDEL--CNA---------IAEESDNINAITAALEATRNELELSCLLPDVSKPXXXXXXXXXXXXXXXXMKTDNVYYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYREQLDNVLTTEKIKHEN---SFNVASGFMCVTSLMNETKQILDDDFVPL 1532
            NEE  Y+ A  Q+ +N    L   +   D    W  ++++  Y+ EDI+CPIC+  P   R   CGH+YCFPC   F+ YEN    +KCA+C+  + +  +KR+  +   S     VGD + L LMRR KS +FPV     +   E  +P         S  AV SN D ++++  DI  +E  L  C +         +AEE      I   L++ RN LE      DV     +   +  ++  ++ ++   +YY+   G+++++  +NW+C+  E+   N+ LP  I+GK++EIE   +  +   RYRYL +LP+G +   VEI+L   +IS  TL +    +  +   R  +++++ +LT  K++ EN   S  V    +   SL NE     D+DFVPL
Sbjct:   96 NEEFDYVTAHCQLLINPHTDLTQVFRDPDAAVAWCDVLEVRCYQVEDIICPICLYPPVSPRMGPCGHIYCFPCAWYFIKYENETLSQKCAVCSTYLRISELKRSPSVRIISSTIPQVGDVVELQLMRRYKSVTFPVHSNNEVTDKENVLPTSELASHFRSRIAVASNHDLRSIVNRDIDDIEAYLLECRSDGLSDCMIPVAEE------ILCLLQSERNALE------DVEP---MTDHAYTLELTDAELEKYFIYYKEVSGNDMYLHSVNWRCLQIEY--GNEELPKAISGKVVEIESRTMNLELRQRYRYLSHLPLGRTFYLVEIDLGPPVISGKTLSEMSEALTMRQLRREEKKRVEKLLTLAKLEAENRIQSLPVGCRLVGHASLDNEVPT--DEDFVPL 480
[Close]
BLAST of RING finger protein vs. TrEMBL
Match: A0A0X3Q3Y2 (RING finger protein 10 (Fragment) OS=Schistocephalus solidus OX=70667 GN=RNF10 PE=4 SV=1)

HSP 1 Score: 170.629 bits (431), Expect = 2.221e-42
Identity = 109/357 (30.53%), Postives = 189/357 (52.94%), Query Frame = 3 
Query:  486 QWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYY-KKCALCNQEIDLKRVKRAAFIERFSLN-VGDNISLLLMRRSKSDSFPVPINLNEARIPYVYSN--ESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINAITAALEATRNELELSCLLPDVSKPXXXXXXXXXXXXXXXXMKTDNV--YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYREQLDNVLTTEKIKHENSFNVASGFMCVTSLMNETKQILDDDFVPLC 1535
            QW+ + ++ ++ TE   CPIC+  P   R   CGH+YC+PC+ +F++Y+N    +KCA+C   +    +KR   +   SL  VG    L+LM+R K+  FP+  + N   IP   ++   S FS  AV ++ D + L+Q +   LE  L    ++  D ++ +   +EA   E     LL +++   + N  +       ++ +++ V  YY+  +G +I++  +NW+C+  ++ D+   LPLRI+G +++IE++ +  D   RYRYL +LPIG    FVE++L    +S  TL +  N +  +S  R  +   + +LT  K + EN          + +  N T+   D+DFVPLC
Sbjct:  119 QWNDVAEVRYFHTEPTNCPICLYPPVAPRMGPCGHIYCWPCIYRFITYDNDLLSRKCAVCGVYLRCSELKR-VLMRPVSLPLVGQTCELVLMKRHKNIMFPLSFSENSTYIPIPNADAASSFFSRVAVATSVDIRNLLQREQCCLETYLAECTSD--DELSCMIPYVEALLCE-----LLKELNSVELTNRDAHTPKTSLNVSESERVYTYYEDVNGLDIYLHSVNWRCLITDYKDRE--LPLRISGTVVQIERYSMNHDLRRRYRYLSHLPIGRPFYFVELDLQPPTVSQKTLDEMSNLLLARSRKREQQLHKEQLLTLAKEEAENRIPTLPLGCRLVAHANLTEVPTDEDFVPLC 465
[Close]
BLAST of RING finger protein vs. TrEMBL
Match: A0A564YPG6 (RING-type domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS7814 PE=4 SV=1)

HSP 1 Score: 168.318 bits (425), Expect = 3.322e-41
Identity = 113/367 (30.79%), Postives = 191/367 (52.04%), Query Frame = 3 
Query:  453 KSEYDF---DDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVPINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINAITAALEATRNELELSCLLPDVSKPXXXXXXXXXXXXXXXXMKTDN--VYYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLSN-IISDSTLRKFKNEIDRKSDNRHYREQLDNVLTTEKIKHENSFN-VASGFMCVTSLMNETKQILDDDFVPL 1532
            K E +F    DI   WD ++ +  Y+TE   CPIC++     R  KCGH+YC PC+ K+   + G + KCA+C + I++  ++R   I      VGD ++  L+RR+K   FP  ++    +  ++    SRF    +       T I+ +I ALE     + A++ ++  +   A+ A  +  +L        K       ++   D    ++++N  VYYQ  DG ++++  +NWKC+  ++   +  LPL+I+GK++E++ + +  D   RY YL++LPIG + S VEI + N ++++ TL+KF  +I R+  NR  R++L+  L  EK   ENS+N +  G   V     E       DFVPL
Sbjct:   88 KEEVEFFKCPDIPFPWDRVLGVRCYQTEVSKCPICLEGLTAPRMGKCGHIYCLPCI-KYCIRDGGDFHKCAVCFKPIEMDDLRRVYIIPSAVPTVGDEVTFTLVRRAKQSIFPKAVHDTAKQHRFL----SRFDLLDLAEQ---LTQIEGEIRALE-----SYAKDYESYGSSMQAISAKSSIRKLK----SEEKKVRCEIETLPPSDFTLDVESNNCYVYYQVIDGKDVYLHSINWKCLLEDYGIGD--LPLQISGKVVEVDSYTMNLDLRRRYGYLKHLPIGRTFSIVEIEIENPVLTEETLKKFSEDIARRLQNRLNRQELELELDIEKELAENSYNSLVPGSRFVGCAKLEGATFSSTDFVPL 435
[Close]
BLAST of RING finger protein vs. TrEMBL
Match: A0A158QG43 (RING-type domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS9945 PE=4 SV=1)

HSP 1 Score: 168.318 bits (425), Expect = 9.022e-40
Identity = 113/367 (30.79%), Postives = 191/367 (52.04%), Query Frame = 3 
Query:  453 KSEYDF---DDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVPINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINAITAALEATRNELELSCLLPDVSKPXXXXXXXXXXXXXXXXMKTDN--VYYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLSN-IISDSTLRKFKNEIDRKSDNRHYREQLDNVLTTEKIKHENSFN-VASGFMCVTSLMNETKQILDDDFVPL 1532
            K E +F    DI   WD ++ +  Y+TE   CPIC++     R  KCGH+YC PC+ K+   + G + KCA+C + I++  ++R   I      VGD ++  L+RR+K   FP  ++    +  ++    SRF    +       T I+ +I ALE     + A++ ++  +   A+ A  +  +L        K       ++   D    ++++N  VYYQ  DG ++++  +NWKC+  ++   +  LPL+I+GK++E++ + +  D   RY YL++LPIG + S VEI + N ++++ TL+KF  +I R+  NR  R++L+  L  EK   ENS+N +  G   V     E       DFVPL
Sbjct:   88 KEEVEFFKCPDIPFPWDRVLGVRCYQTEVSKCPICLEGLTAPRMGKCGHIYCLPCI-KYCIRDGGDFHKCAVCFKPIEMDDLRRVYIIPSAVPTVGDEVTFTLVRRAKQSIFPKAVHDTAKQHRFL----SRFDLLDLAEQ---LTQIEGEIRALE-----SYAKDYESYGSSMQAISAKSSIRKLK----SEEKKVRCEIETLPPSDFTLDVESNNCYVYYQVIDGKDVYLHSINWKCLLEDYGIGD--LPLQISGKVVEVDSYTMNLDLRRRYGYLKHLPIGRTFSIVEIEIENPVLTEETLKKFSEDIARRLQNRLNRQELELELDIEKELAENSYNSLVPGSRFVGCAKLEGATFSSTDFVPL 435
[Close]
BLAST of RING finger protein vs. Ensembl Cavefish
Match: rnf10 (ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-2969])

HSP 1 Score: 85.1149 bits (209), Expect = 9.846e-17
Identity = 52/179 (29.05%), Postives = 84/179 (46.93%), Query Frame = 3 
Query:  474 DIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKS--DSFPV--------PINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINA--ITAAL 974
            D    WDS+ Q+  Y  E   CPIC+  P  +   +CGH+YC+PC+  +LS     + KC +C + +    +K    +E      GD I++ LMRR K    + P         PI + + R+       S +S   + S E   +L+  +  AL+ +L    ++E D+  A  I +AL
Sbjct:  205 DTLVSWDSVQQVRIYSHEVPTCPICLYPPVAAHITRCGHIYCWPCMLHYLSLSEKSWSKCPICYEAVHSADLKSVVAMETHQYVPGDVITMRLMRREKGVLVALPSSQWVKVEEPIRIGDVRL-------SAYSKLLLASREQVLSLLTEERGALQMQL----SQEKDDPQACFIQSAL 372

HSP 2 Score: 65.4698 bits (158), Expect = 1.231e-10
Identity = 33/94 (35.11%), Postives = 54/94 (57.45%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRK 1376
            +YQ+EDG  +F+ P+N +C+  E+       P  IT  ++EIE   +  D   R+RYL +LP+    S  E+NL   I+S  TL  F ++I+++
Sbjct:  456 FYQAEDGQQMFLHPVNVRCLLREYGSLENS-PQSITASVVEIEGHTVNEDVRRRHRYLSHLPLTCEFSICELNLQPPILSKETLDSFSDDIEKR 548
[Close]
BLAST of RING finger protein vs. Ensembl Sea Lamprey
Match: rnf10 (ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-030131-2969])

HSP 1 Score: 76.2554 bits (186), Expect = 9.079e-15
Identity = 28/86 (32.56%), Postives = 50/86 (58.14%), Query Frame = 3 
Query:  531 IMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP 788
            + CPIC+  P  +R  +CGHV+C+PC+  +L+  +  ++KC +C + +  K ++     E     VGD ++L LM+R K  +  +P
Sbjct:   12 LSCPICLYPPTAARITRCGHVFCWPCILHYLALSDEPWRKCPICFEAVHKKHLRSVVTKETHQFAVGDTVTLQLMKREKGSAIALP 97

HSP 2 Score: 75.0998 bits (183), Expect = 2.056e-14
Identity = 36/94 (38.30%), Postives = 59/94 (62.77%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINL-SNIISDSTLRKFKNEIDRK 1376
            YYQ+EDG +++M P+N +C+  E      C P R+T +IM+IE F +T     RY YL +LP+   +SF E+ L   +++ +TL+ F  +I+R+
Sbjct:  285 YYQAEDGQHMYMLPMNRRCLLQEHGGPEGC-PDRVTARIMDIESFSMTEYHRKRYNYLDHLPLTCEISFCEVVLHPPLVTQATLQYFTADIERR 377
[Close]
BLAST of RING finger protein vs. Ensembl Yeast
Match: MAG2 (Cytoplasmic protein of unknown function; induced in response to mycotoxin patulin; ubiquitinated protein similar to the human ring finger motif protein RNF10; predicted to be involved in repair of alkylated DNA due to interaction with MAG1 [Source:SGD;Acc:S000004419])

HSP 1 Score: 70.8626 bits (172), Expect = 3.610e-13
Identity = 84/328 (25.61%), Postives = 141/328 (42.99%), Query Frame = 3 
Query:  537 CPICM-DAPKVSRTDKCGHVYCFPCLNKFLSYE-------NGY-----YKKCALCNQEIDLKRVKRAAFIERFSLN-------VGDNISLLLMRRSKSDSFPVPINLNEARI------PYVYSNESRFSNTAVCSNEDFQTLIQIDIMALED--ELCNAIAEES--------DNIN-AITAALEATRNELELSCLLPDVSKPXXXXXXXXXXXXXXXXMKTDN----VYYQSEDGSNI--FMCPLNWKCM--SFEFLDKNQCLPLRITGKIMEIE-KFVITPDFINRYRYLRYLPIGSSVSFVEINLSNI--ISDSTLRKFKNEIDRK 1376
            C IC+ + P   R   CGH++C  CL  F S E        GY     YK+C LC   I  KRVK   + + F +         G  + L LM +      P+P+ L+   +      P    +   +++   C       L Q DI+A+++  E+  AI  +S        +NIN  I+  L AT    +LS L  D++             D + + K D+     +YQ+   S+   F+ PL+ K +   F +  K    P  I   +  I    V+T   I RY+Y+ +LPIG+ ++ ++++   I  +      +F +E+ ++
Sbjct:  195 CSICLSEEPVAPRMVTCGHIFCLSCLLNFFSIEETVKNKETGYSKKKKYKECPLCGSIIGPKRVKPVLYEDDFDVTRLNQKPEPGATVHLQLMCKPHGSLLPLPVALHLDPLKCGNFPPANLGSIKHYAHIMKCGVSYSLELYQKDIVAIQEQYEIDKAIYNDSGKFVKQSIENINDQISTLLAAT---TDLSPLSNDINN-----GLDNFHFDDDLLTKYDDSSAYFFYQTLVASSTKYFLSPLDVKILLTIFHYYSK---FPESIETTVENIHYDTVVTEQLIRRYKYIGHLPIGTEIALLDLDWRKIPFLPKEIYEQFAHELKQR 511
[Close]
BLAST of RING finger protein vs. Ensembl Yeast
Match: SLX8 (Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; role in proteolysis of spindle positioning protein Kar9, DNA repair proteins Rad52p and Rad57p; stimulated by SUMO-modified substrates; contains a C-terminal RING domain; forms nuclear foci upon DNA replication stress; required for maintenance of genome integrity like human ortholog RNF [Source:SGD;Acc:S000000918])

HSP 1 Score: 48.9062 bits (115), Expect = 1.087e-6
Identity = 23/76 (30.26%), Postives = 38/76 (50.00%), Query Frame = 3 
Query:  471 DDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENG--YYKKCALCNQEIDLKRVK 692
            DD + +        +   +D  CPIC + P+ +    CGHV+C PCL + ++       +  CALC  ++ LK V+
Sbjct:  184 DDDFQEETKEAPKEYGAAKDYRCPICFEPPETALMTLCGHVFCCPCLFQMVNSSRTCRQFGHCALCRSKVYLKDVR 259
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BLAST of RING finger protein vs. Ensembl Nematostella
Match: EDO47488 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLV2])

HSP 1 Score: 66.6254 bits (161), Expect = 2.031e-11
Identity = 34/106 (32.08%), Postives = 61/106 (57.55%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLS-NIISDSTLRKFKNEIDRKSDNRHYREQLDN 1412
            +YQ++DG NIF+ P+N +C+  E+       P  +  KI E+E    T D   R+RYL YLP+       E++L   ++S +TL+ F+ E+ +++  R  + +++N
Sbjct:  459 FYQADDGQNIFLHPINARCLIKEYGSLENS-PEYLEAKIKELEPMSQTEDSRKRFRYLSYLPLTCEFVMCEVDLGPPVLSKNTLQVFREELQKRNQRRQKKIKMEN 563
[Close]
BLAST of RING finger protein vs. Ensembl Nematostella
Match: EDO41454 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4D3])

HSP 1 Score: 47.3654 bits (111), Expect = 4.206e-7
Identity = 20/56 (35.71%), Postives = 31/56 (55.36%), Query Frame = 3 
Query:  519 KTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKR 686
            + ++++CPIC+D  K  +T  C H  C  CL    + E+    +C LC  EID+ R
Sbjct:    4 QLDELLCPICLDEFKEPKTLSCMHDLCRKCLEDMAARESSRVIRCPLCRSEIDIPR 59
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BLAST of RING finger protein vs. Ensembl Medaka
Match: rnf10 (ring finger protein 10 [Source:NCBI gene;Acc:101166478])

HSP 1 Score: 83.1889 bits (204), Expect = 3.792e-16
Identity = 35/112 (31.25%), Postives = 58/112 (51.79%), Query Frame = 3 
Query:  453 KSEYDFDDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVP 788
            K+ +   D    WD + Q+  +  E   CPIC+  P  +R  +CGH++C+PC+  +LS  +  + KC +C + +    +K    +E     VGD I++ LMRR K     +P
Sbjct:  194 KAHFTDPDTLVNWDCVQQVRIHSHEVPSCPICLYPPVAARITRCGHIFCWPCMLHYLSLSDKSWSKCPICYEAVHTADLKSVVAMETRQYVVGDVITMRLMRREKGALVAMP 305

HSP 2 Score: 61.2326 bits (147), Expect = 2.430e-9
Identity = 32/101 (31.68%), Postives = 55/101 (54.46%), Query Frame = 3 
Query: 1098 YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINL-SNIISDSTLRKFKNEIDRKSDNRHYR 1397
            +YQ+ED   +F+ PLN +C+  E+     C P  IT  ++EI    +T D   R+RYL +LP+    S  E+ L   ++S  TL  F ++++++   R  +
Sbjct:  487 FYQAEDCQQMFLHPLNVRCLLREYGSLEAC-PDSITATVVEIVGHTVTEDIRRRHRYLAHLPLTCEFSICELVLEPPVVSKETLDTFADDLEKRRRMRQKK 586
[Close]
BLAST of RING finger protein vs. Planmine SMEST
Match: SMESG000016827.1 (SMESG000016827.1)

HSP 1 Score: 1013.45 bits (2619), Expect = 0.000e+0
Identity = 507/507 (100.00%), Postives = 507/507 (100.00%), Query Frame = 3 
Query:  198 MDKKLTTTRNLNRDLKNTATKYRIPDYTNEKHFSSAKVKQYNYYRPQHRGCNYKKSLEYQSESVSLSNEEYIHATSQIWLNQKCLKSEYDFDDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVPINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINAITAALEATRNELELSCLLPDVSKPXXXXXXXXXXXXXXXXMKTDNVYYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLSNIISDSTLRKFKNEIDRKSDNRHYREQLDNVLTTEKIKHENSFNVASGFMCVTSLMNETKQILDDDFVPLCPNVPTSSHAPNINVSSDKKMSYAELMHLKKTPVNYQSIAENPSDAPGEAQSRGFSLQDCLV 1718
            MDKKLTTTRNLNRDLKNTATKYRIPDYTNEKHFSSAKVKQYNYYRPQHRGCNYKKSLEYQSESVSLSNEEYIHATSQIWLNQKCLKSEYDFDDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVPINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINAITAALEATRNELELSCLLPDVSKPSIINSSSIEIDDLNSIMKTDNVYYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLSNIISDSTLRKFKNEIDRKSDNRHYREQLDNVLTTEKIKHENSFNVASGFMCVTSLMNETKQILDDDFVPLCPNVPTSSHAPNINVSSDKKMSYAELMHLKKTPVNYQSIAENPSDAPGEAQSRGFSLQDCLV
Sbjct:    1 MDKKLTTTRNLNRDLKNTATKYRIPDYTNEKHFSSAKVKQYNYYRPQHRGCNYKKSLEYQSESVSLSNEEYIHATSQIWLNQKCLKSEYDFDDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVPINLNEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESDNINAITAALEATRNELELSCLLPDVSKPSIINSSSIEIDDLNSIMKTDNVYYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPDFINRYRYLRYLPIGSSVSFVEINLSNIISDSTLRKFKNEIDRKSDNRHYREQLDNVLTTEKIKHENSFNVASGFMCVTSLMNETKQILDDDFVPLCPNVPTSSHAPNINVSSDKKMSYAELMHLKKTPVNYQSIAENPSDAPGEAQSRGFSLQDCLV 507
[Close]
BLAST of RING finger protein vs. Planmine SMEST
Match: SMESG000076269.1 (SMESG000076269.1)

HSP 1 Score: 58.9214 bits (141), Expect = 7.980e-9
Identity = 31/114 (27.19%), Postives = 56/114 (49.12%), Query Frame = 3 
Query:  444 KCLKSEYDFDDIYSQWDSIIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYKKCALCNQ-EIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFP 782
            K L++ +DF      W S+ +I  +  +  +C IC D   ++R D+CGH++C  C+          +  C +C   EI +  +KR  F E+    +G+ I L L+ + + +  P
Sbjct:   25 KFLRNIHDFS-----WTSVSKIICFTNDSKVCSICFDKIILARMDRCGHIFCLSCILSVFDVNKSNHAPCPMCKDVEISINSLKRVEFHEQKLPIIGEPIKLSLLVKGQQNVCP 133
The following BLAST results are available for this feature:
BLAST of RING finger protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RNF105.865e-1627.72ring finger protein 10 [Source:HGNC Symbol;Acc:HGN... [more]
RNF103.753e-1328.02ring finger protein 10 [Source:HGNC Symbol;Acc:HGN... [more]
RNF103.904e-1328.02ring finger protein 10 [Source:HGNC Symbol;Acc:HGN... [more]
RNF108.923e-1130.10ring finger protein 10 [Source:HGNC Symbol;Acc:HGN... [more]
RNF109.770e-1027.52ring finger protein 10 [Source:HGNC Symbol;Acc:HGN... [more]
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BLAST of RING finger protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of RING finger protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CG120991.814e-2526.14gene:FBgn0035232 transcript:FBtr0072829[more]
CG120991.814e-2526.14gene:FBgn0035232 transcript:FBtr0072828[more]
CG430586.862e-640.68gene:FBgn0262360 transcript:FBtr0304641[more]
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BLAST of RING finger protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rnf102.919e-1527.75ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
rnf105.835e-1227.50ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of RING finger protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
egfl72.396e-1331.31EGF like domain multiple 7 [Source:Xenbase;Acc:XB-... [more]
egfl72.685e-1330.48EGF like domain multiple 7 [Source:Xenbase;Acc:XB-... [more]
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BLAST of RING finger protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Rnf101.928e-1327.50ring finger protein 10 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf102.302e-1326.78ring finger protein 10 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf102.405e-1326.78ring finger protein 10 [Source:MGI Symbol;Acc:MGI:... [more]
Rnf102.428e-1326.78ring finger protein 10 [Source:MGI Symbol;Acc:MGI:... [more]
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BLAST of RING finger protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q32NQ8|RNF10_XENLA4.383e-1433.33RING finger protein 10 OS=Xenopus laevis OX=8355 G... [more]
sp|Q08E13|RNF10_BOVIN7.262e-1324.75RING finger protein 10 OS=Bos taurus OX=9913 GN=RN... [more]
sp|Q3UIW5|RNF10_MOUSE1.682e-1226.78RING finger protein 10 OS=Mus musculus OX=10090 GN... [more]
sp|Q8N5U6|RNF10_HUMAN1.875e-1228.02RING finger protein 10 OS=Homo sapiens OX=9606 GN=... [more]
sp|Q5XI59|RNF10_RAT2.030e-1227.78RING finger protein 10 OS=Rattus norvegicus OX=101... [more]
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BLAST of RING finger protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5K3FVE51.159e-4331.42Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A0R3UAQ72.080e-4231.19Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A0X3Q3Y22.221e-4230.53RING finger protein 10 (Fragment) OS=Schistocephal... [more]
A0A564YPG63.322e-4130.79RING-type domain-containing protein OS=Hymenolepis... [more]
A0A158QG439.022e-4030.79RING-type domain-containing protein OS=Hymenolepis... [more]
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BLAST of RING finger protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rnf109.846e-1729.05ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of RING finger protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rnf109.079e-1532.56ring finger protein 10 [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of RING finger protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
MAG23.610e-1325.61Cytoplasmic protein of unknown function; induced i... [more]
SLX81.087e-630.26Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligas... [more]
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BLAST of RING finger protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO474882.031e-1132.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO414544.206e-735.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of RING finger protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rnf103.792e-1631.25ring finger protein 10 [Source:NCBI gene;Acc:10116... [more]
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BLAST of RING finger protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000016827.10.000e+0100.00SMESG000016827.1[more]
SMESG000076269.17.980e-927.19SMESG000076269.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021994 ID=SMED30021994|Name=RING finger protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2013bp
TTTCACTTTCACAAGGTTGCTTTTTGTAACCTTATTTATTCTTTTTGCGC
CTACTTAGATTGTTAGAAACAACAGATTTTAAAATTTCCAATTAACGAAA
CAATTTTTAAATTTGCATTATTATTATTATGGCTTGTTAAATATGTTCAA
TATTTCAATACGATATAATAAATTTTACGAATTACTTCTACTTAGTAATG
GACAAAAAATTAACCACTACTCGAAATTTGAACAGAGATTTAAAGAACAC
GGCCACAAAATATCGGATTCCAGATTATACAAACGAAAAGCATTTTTCAT
CGGCAAAAGTGAAACAATACAATTATTACCGACCCCAACATAGAGGTTGT
AATTACAAAAAATCCCTTGAATATCAAAGTGAATCAGTTTCACTGTCTAA
TGAAGAATATATTCACGCTACTTCTCAAATATGGTTGAATCAAAAATGTT
TGAAATCCGAATATGATTTCGATGACATTTATAGTCAATGGGATTCAATT
ATTCAAATTAATTTCTACAAAACAGAAGATATTATGTGTCCTATTTGTAT
GGATGCTCCAAAGGTTAGCCGAACCGATAAATGTGGCCATGTTTATTGTT
TTCCGTGTTTGAATAAATTTCTATCATATGAAAATGGATATTATAAAAAA
TGCGCTCTATGTAATCAGGAAATTGATTTAAAAAGAGTAAAACGGGCGGC
TTTTATTGAACGATTTTCATTAAATGTTGGAGATAACATTTCTTTATTAT
TAATGAGACGATCAAAATCCGATTCATTTCCCGTTCCAATCAATCTTAAT
GAAGCCAGAATTCCCTATGTATACTCAAATGAGAGTAGATTTTCTAACAC
AGCTGTTTGCTCTAATGAAGACTTTCAAACTTTGATTCAAATCGATATAA
TGGCTCTCGAAGATGAATTGTGTAATGCCATAGCGGAAGAAAGCGACAAT
ATCAATGCCATTACTGCGGCTTTAGAAGCTACTAGAAACGAATTGGAATT
ATCTTGTCTCCTTCCTGACGTATCTAAACCATCAATCATTAATTCATCTT
CGATCGAAATCGATGATTTGAATTCCATAATGAAAACTGACAATGTTTAT
TATCAATCCGAAGATGGAAGCAATATATTTATGTGTCCATTAAATTGGAA
ATGCATGAGCTTTGAATTCTTAGATAAAAATCAATGTTTGCCACTGAGAA
TTACTGGTAAAATAATGGAAATAGAAAAATTTGTAATTACGCCGGATTTC
ATCAATCGATATCGATATTTGAGATATTTACCCATTGGTTCCTCTGTTAG
CTTTGTGGAAATAAATCTCTCAAATATCATTTCCGATTCAACACTGAGAA
AATTTAAAAACGAAATCGATCGCAAATCTGACAATCGGCATTATAGAGAA
CAACTGGATAATGTTTTGACGACGGAAAAAATAAAACACGAAAATTCTTT
CAACGTTGCCAGCGGATTTATGTGCGTTACGTCGTTGATGAATGAAACGA
AACAAATTTTAGATGATGATTTCGTTCCGTTGTGCCCAAATGTCCCGACA
TCTTCCCATGCTCCTAATATTAATGTTTCCAGTGACAAAAAAATGAGTTA
TGCTGAGTTGATGCACTTGAAAAAGACGCCTGTAAATTATCAATCCATAG
CGGAAAATCCATCAGATGCCCCTGGAGAAGCCCAATCTCGAGGATTCTCT
TTGCAAGACTGCTTGGTGAAGAAGTCAAATAAACGTAACAGGAAAAAGTG
ACCAATAAATGGCACATAATTTCCACATTTTGGTTTAAGGTTATCCACGT
GTAAATTTTCCCAATTGAAATATTTATTATGGAGTGGAATAAATGTCTGC
TTTCGTGATTTTTCTTCAATGAATTTTATCAATCGATAATTCTATTGATT
TTATTTTTGAATTTATTATTTTATAATTTGAGTAAAATTCTTTATTTTGA
TTGGCTGGAATTTGAATTTTGCTGAAGGTCATGTTGTAATATAAATGATA
AATTCAAATAAAT
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protein sequence of SMED30021994-orf-1

>SMED30021994-orf-1 ID=SMED30021994-orf-1|Name=SMED30021994-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=518bp
MDKKLTTTRNLNRDLKNTATKYRIPDYTNEKHFSSAKVKQYNYYRPQHRG
CNYKKSLEYQSESVSLSNEEYIHATSQIWLNQKCLKSEYDFDDIYSQWDS
IIQINFYKTEDIMCPICMDAPKVSRTDKCGHVYCFPCLNKFLSYENGYYK
KCALCNQEIDLKRVKRAAFIERFSLNVGDNISLLLMRRSKSDSFPVPINL
NEARIPYVYSNESRFSNTAVCSNEDFQTLIQIDIMALEDELCNAIAEESD
NINAITAALEATRNELELSCLLPDVSKPSIINSSSIEIDDLNSIMKTDNV
YYQSEDGSNIFMCPLNWKCMSFEFLDKNQCLPLRITGKIMEIEKFVITPD
FINRYRYLRYLPIGSSVSFVEINLSNIISDSTLRKFKNEIDRKSDNRHYR
EQLDNVLTTEKIKHENSFNVASGFMCVTSLMNETKQILDDDFVPLCPNVP
TSSHAPNINVSSDKKMSYAELMHLKKTPVNYQSIAENPSDAPGEAQSRGF
SLQDCLVKKSNKRNRKK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
PLANA:0002056medial muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR039739Mag2/Rnf10
IPR001841Znf_RING
IPR013083Znf_RING/FYVE/PHD
IPR017907Znf_RING_CS
Vocabulary: molecular function
TermDefinition
GO:0008270zinc ion binding
GO:0005515protein binding
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 245..265
NoneNo IPR availablePFAMPF13920zf-C3HC4_3coord: 111..160
e-value: 1.5E-8
score: 34.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 484..517
NoneNo IPR availableCDDcd16536RING-HC_RNF10coord: 114..156
e-value: 3.73525E-14
score: 64.5077
NoneNo IPR availableSUPERFAMILYSSF57850RING/U-boxcoord: 95..162
IPR001841Zinc finger, RING-typeSMARTSM00184ring_2coord: 114..155
e-value: 4.3E-6
score: 36.2
IPR001841Zinc finger, RING-typePROSITEPS50089ZF_RING_2coord: 114..156
score: 10.793
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 98..182
e-value: 6.1E-12
score: 47.1
IPR039739RING-finger protein Mag2/Rnf10PANTHERPTHR12983FAMILY NOT NAMEDcoord: 54..415
IPR017907Zinc finger, RING-type, conserved sitePROSITEPS00518ZF_RING_1coord: 129..138