Protocadherin alpha-11
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021961 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Protocadherin alpha-11 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 228.409 bits (581), Expect = 1.582e-60 Identity = 213/764 (27.88%), Postives = 363/764 (47.51%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL-----PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQ---IIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIF-PNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G+ IDR+ +LCA + C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN P+F+ + SI N + +++ ++HATD DI NA + + FS V I + F LN ++ +K+ L E ++ + A D G ++ V + N N+ PSI + P N+ V+ + EN + I V D D+ +G+ C +++I + S L T D E + + D GKP N SA + I + D NDN+P F + F +I E N P + +++A D D G NA++ Y L P+ + +C+ + ++ LDREK + ++A D+G P + + TV + ++D NDN PVF YN E+ V + DPD+G N VT SI+ E F ++ +G + DRE Q S YTF + A D ++++ V+I + D NDN+P+FI P+ +Y++ L P G++V V A+D D+G+N+++++ + LF+I++ +G + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDRE---KLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT-LPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV-TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE-ETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNV--PSIDIRYIVNPVNDTVV-LSENIPLNTKIALITVTDKDADHNGRVTCF----TDHEIPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-------LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYL-----FTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGT---VGLITVTDPDYGDNSAVTLSILDEN-DDFTIDSQTGVIRPNISFDREKQES-YTFYVKAEDGGR---VSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 228.409 bits (581), Expect = 3.799e-60 Identity = 214/764 (28.01%), Postives = 365/764 (47.77%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL-----PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQ---IIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIF-PNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G+ IDR+ +LCA + C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN P+F+ + SI N + +++ ++HATD DI NA + + FS V I + F LN ++ +K+ L E ++ + A D G ++ V + N N+ PSI + P N+ V+ + EN + I V D D+ +G+ C +++I + S L T D E + + D GKP N SA + I + D NDN+P F + F +I E N P + +++A D D G NA++ Y L P+ + +C+ + ++ LDREK + + F ++A D+G P + + TV + ++D NDN PVF YN E+ V + DPD+G N VT SI+ E F ++ +G + DRE Q S YTF + A D ++++ V+I + D NDN+P+FI P+ +Y++ L P G++V V A+D D+G+N+++++ + LF+I++ +G + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDRE---KLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT-LPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV-TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE-ETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNV--PSIDIRYIVNPVNDTVV-LSENIPLNTKIALITVTDKDADHNGRVTCFT----DHEIPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-------LLGPDAPPEFSLDCRTGMLTVVKKLDREKE-DKYLFT----ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGT---VGLITVTDPDYGDNSAVTLSILDEN-DDFTIDSQTGVIRPNISFDREKQES-YTFYVKAEDGGR---VSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 228.024 bits (580), Expect = 4.744e-60 Identity = 214/764 (28.01%), Postives = 365/764 (47.77%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL-----PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQ---IIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIF-PNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G+ IDR+ +LCA + C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN P+F+ + SI N + +++ ++HATD DI NA + + FS V I + F LN ++ +K+ L E ++ + A D G ++ V + N N+ PSI + P N+ V+ + EN + I V D D+ +G+ C +++I + S L T D E + + D GKP N SA + I + D NDN+P F + F +I E N P + +++A D D G NA++ Y L P+ + +C+ + ++ LDREK + + F ++A D+G P + + TV + ++D NDN PVF YN E+ V + DPD+G N VT SI+ E F ++ +G + DRE Q S YTF + A D ++++ V+I + D NDN+P+FI P+ +Y++ L P G++V V A+D D+G+N+++++ + LF+I++ +G + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDRE---KLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT-LPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV-TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE-ETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNV--PSIDIRYIVNPVNDTVV-LSENIPLNTKIALITVTDKDADHNGRVTCF----TDHEIPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-------LLGPDAPPEFSLDCRTGMLTVVKKLDREKE-DKYLFT----ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGT---VGLITVTDPDYGDNSAVTLSILDEN-DDFTIDSQTGVIRPNISFDREKQES-YTFYVKAEDGGR---VSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 228.024 bits (580), Expect = 5.284e-60 Identity = 214/764 (28.01%), Postives = 365/764 (47.77%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL-----PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQ---IIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIF-PNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G+ IDR+ +LCA + C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN P+F+ + SI N + +++ ++HATD DI NA + + FS V I + F LN ++ +K+ L E ++ + A D G ++ V + N N+ PSI + P N+ V+ + EN + I V D D+ +G+ C +++I + S L T D E + + D GKP N SA + I + D NDN+P F + F +I E N P + +++A D D G NA++ Y L P+ + +C+ + ++ LDREK + + F ++A D+G P + + TV + ++D NDN PVF YN E+ V + DPD+G N VT SI+ E F ++ +G + DRE Q S YTF + A D ++++ V+I + D NDN+P+FI P+ +Y++ L P G++V V A+D D+G+N+++++ + LF+I++ +G + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDRE---KLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT-LPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV-TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE-ETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNV--PSIDIRYIVNPVNDTVV-LSENIPLNTKIALITVTDKDADHNGRVTCF----TDHEIPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-------LLGPDAPPEFSLDCRTGMLTVVKKLDREKE-DKYLFT----ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGT---VGLITVTDPDYGDNSAVTLSILDEN-DDFTIDSQTGVIRPNISFDREKQES-YTFYVKAEDGGR---VSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 228.024 bits (580), Expect = 5.675e-60 Identity = 214/764 (28.01%), Postives = 365/764 (47.77%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL-----PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQ---IIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIF-PNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G+ IDR+ +LCA + C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN P+F+ + SI N + +++ ++HATD DI NA + + FS V I + F LN ++ +K+ L E ++ + A D G ++ V + N N+ PSI + P N+ V+ + EN + I V D D+ +G+ C +++I + S L T D E + + D GKP N SA + I + D NDN+P F + F +I E N P + +++A D D G NA++ Y L P+ + +C+ + ++ LDREK + + F ++A D+G P + + TV + ++D NDN PVF YN E+ V + DPD+G N VT SI+ E F ++ +G + DRE Q S YTF + A D ++++ V+I + D NDN+P+FI P+ +Y++ L P G++V V A+D D+G+N+++++ + LF+I++ +G + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDRE---KLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT-LPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV-TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE-ETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNV--PSIDIRYIVNPVNDTVV-LSENIPLNTKIALITVTDKDADHNGRVTCF----TDHEIPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-------LLGPDAPPEFSLDCRTGMLTVVKKLDREKE-DKYLFT----ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGT---VGLITVTDPDYGDNSAVTLSILDEN-DDFTIDSQTGVIRPNISFDREKQES-YTFYVKAEDGGR---VSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 181.03 bits (458), Expect = 1.713e-45 Identity = 184/676 (27.22%), Postives = 314/676 (46.45%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSL-NVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRI-QWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRN---ILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
+ +LD DN P + ++S E+ E+ + + L + ARD D N I Y E K + KS ++ +DRE +S + ++A D GTP + + + I ++DVNDN P+F S Y +I N+ I + + + ATD D N +S+ + I D + LR + K+ + R A D +P S +T+++ + N + P+++ +I + EN IG + D DSG +G S+ +++ I E+ +I T K+ DRE R L + +D G P+ NTS I++++ D+NDN+P F+K+ Y+ TI EE I L A D D+ + ++ YRI + D ++ ++ + I+++ L R+ + ++ ATD G Q G V++ + D+N + P F +++ E V A D D G N + YSI F+++P+SG++ +DRE + + ++ +TA D + L T + ++++D NDN P F S+Y +S +PVG+ V AID D G N + + L E + LF ++ TSG L S+ L L I A D G+P L+A ++T+ + +
Sbjct: 258 VHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSV-FARDLDSGENGEIEYSLGEGNGKNLLAINAKSG-----VIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVI-ATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAVIR----AKDGAQPALSSTVPLTINVIDINDHAPTLI--AAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFII--------DEDSGLIK--TTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE--DQKITYRIEEADREVF---SILDIGDQGAILSVSGELKRQDHK------VRVEISATDQGGLQ--GRCVVNVFIDDVN-SAPYFNDHPFSVKIPE---HSPIGYPVITLKAEDHDRGDNARIVYSIDSSQF--FRIDPSSGDISVSSDLDREDR-ATFSVIVTASDHASPPLNTST---QIEVILDDINDNSPQF---TSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSD 884 HSP 2 Score: 140.969 bits (354), Expect = 3.018e-33 Identity = 169/632 (26.74%), Postives = 288/632 (45.57%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP----FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINE 2253
++EI ++D NDN P ++ +S + ++EN + + + KA D D N +Y + +S ++ + S + LR ID + S + A DG P+ + ++ L I +ID+ND+ P ++ +++ N+ I + +++A D D N ++S+ + F ++ + +++ K L E A Y + A D G P + TT+ + LK+ N P+ N + I E G I+T DND D K I E + ++ ++ + AI+S ++ ++ ++ K R++ I D G +++ I DVN ++P F + I E + + + L A D D G NA++ Y I D ++ +++ + I++ S LDRE R V A+D P + ST + + L DINDN P F + Y + ED + +V+ A D D G NG V Y + + P F+L+ SG L +DRE Q + I ARD T L +A +++ + D NDN P F + +Y + ++ PVGS V + A D D G N+ I F + LF I E
Sbjct: 360 MVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATV-KATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEV----TLRERIDAK-NSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVG-RVYAIDEDSGPNGIIKYSME----GSEDFIIDEDSGLIKTTKLLDRETTA-RYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYN--VTISEEMPRGSQIITLKAVDNDE--DQKITYRI-EEADREVFSILD--IGDQGAILS-VSGELKRQDHKVRVE--ISATDQG--GLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI-------DSSQFFRIDPSSGDISVSSDLDRED-----RATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVS---AIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDRE-QFAVIVLPIFARDRGTPSL---SAASEITLTLSDVNDNAPTF---EQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEE 944 HSP 3 Score: 134.806 bits (338), Expect = 2.348e-31 Identity = 120/418 (28.71%), Postives = 203/418 (48.56%), Query Frame = 1
Query: 1201 EPKNYDIILTMNKTKSENIAIISLITNKI-----FDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPN--KLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRET-LLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETE 2427
+P Y ++ + ++S+N+ + ++ +I DREV + L + + P + S + + ++DV DNSP FEK+ Y I E+ T+ + A DLD G N ++ Y SL + N L+ + + +I + LDRE + VIA+D G P+R + V I ++D+NDN PVF YN++ LE+ +A A D DFG NG V YS+ + + ++ ++GE+ + +D + P T I A+D L ++TV ++I + D ND+ P I + I L V +G V V AID+DSG N I++ +E + F I+E SG + T+ +L +L + A D G+P L + + + + N ++ F++ E
Sbjct: 195 QPLYYSMVAPQD-SRSQNLFTLDTMSGEIRLAKSMDREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEY------SLGEGNGKNLLAINAKSGVIQTAAPLDRETLS-----LIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPA---VIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSP--ITAVIRAKDGAQPAL---SSTVPLTINVIDINDHAPTLI---AAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED---FIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDI-NDNAPTFDKKE 585 HSP 4 Score: 134.035 bits (336), Expect = 3.585e-31 Identity = 171/702 (24.36%), Postives = 301/702 (42.88%), Query Frame = 1
Query: 406 NVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPT---SKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV---RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIVGIILGTFFI 2493
N + Q V E+ E+T +++ + KA + P + Y + P S+ F S + ++L + +DRE++ H + + A + P+ + S +++ ++DV DN PIFE Y I + I +T+ L + A DLD N +SL ++ +N + +++ L E S R + A D G P +S V + + + N P + ++ + I+EN I VI T D D G +GK + S+ LT++ + E + + I K + I +I KD +PA +++ ++I +ID+ND++P T+ E + ++ A D D G N ++Y S+ I E + I + LDRE R+ +V A D G P + STT+++ L DINDN P F + YN++ E+ R + D + +TY I RE + L + R+ + S T + V++ I+D N + P F N+ + +++ P+G V +KA D D G N++I + ++ + F I+ +SG++ S+ L + ++ + A D SP L Q+ + + + N +S F S A I I +GT F+
Sbjct: 161 NAVHFQQEKYVKELPEDTPIETIIASV-KASHASSQP--LYYSMVAPQDSRSQNLFTLDTMSGE-----IRLAKSMDREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTV-LSVFARDLDSGENGEIEYSLG-EGNGKNLLAINAKSGVIQTAAPLDRETL-SLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAP--VFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIG-GLTIDYSTGE-VTLRERIDAK------NSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKY------SMEGSEDFIIDEDSGLIKTTKLLDRETTA---RY--SLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEM-----PRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKVRVEISATDQGG-------LQGRCVVNVFIDDVN-SAPYF---NDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQ---FFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDI-NDNSPQFTS------SSYAATISEDIPVGTSFL 804 HSP 5 Score: 90.5077 bits (223), Expect = 7.727e-18 Identity = 134/557 (24.06%), Postives = 226/557 (40.57%), Query Frame = 1
Query: 190 PSDTTKFKLIKNRFFQIENGDNL-KVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEIN-STLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRI--QWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPD 1848
P+ K+ + + F I+ L K + L+DR+ + R + N + + + D NDN P + + + + E S + L KA D+DE + Y+IE + F + ++G L + + R+ V + A D G G + + I DVN + P F ++ I + I + LK D NA + Y + F ++P + + V L E A+ + + A DH P + T + + L + N P A I E+ +G L D D G +G + + E + I ++ +L + DRE I L IF +D G P+ + ++EI++ + DVNDN+P FE+ Y I E + T+ + A D D+G NA + +RI D L+D + + +I+ D E N F F + SG Q S + V I + D+NDN P + + + F + + +R++ A DPD
Sbjct: 510 PNGIIKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARY------SLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITL-KAVDNDE--DQKITYRIEEADREVFSILDIGDQG--AILSVSGELKRQDHKVR-VEISATDQG--GLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS------QFFRIDPSSGDISVSSDLDREDRAT-FSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATIS--EDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSG----TLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFF-----ELQASSG--QLSSTVPVRIHVSDVNDNKPALKDF---VILMNRFDNVQMARQIGFIPAFDPD 1028
BLAST of Protocadherin alpha-11 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 151.754 bits (382), Expect = 1.326e-36 Identity = 155/565 (27.43%), Postives = 264/565 (46.73%), Query Frame = 1
Query: 712 IKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSL-NVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRI-QWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRN---ILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
I ++DVNDN P+F S Y +I N+ I + + + ATD D N +S+ + I D + LR + K+ + R A D +P S +T+++ + N + P+++ +I + EN IG + D DSG +G S+ +++ I E+ +I T K+ DRE R L + +D G P+ NTS I++++ D+NDN+P F+K+ Y+ TI EE I L A D D+ + ++ YRI + D ++ ++ + I+++ L R+ + ++ ATD G Q G V++ + D+N + P F +++ E V A D D G N + YSI F+++P+SG++ +DRE + + ++ +TA D + L T + ++++D NDN P F S+Y +S +PVG+ V AID D G N + + L E + LF ++ TSG L S+ L L I A D G+P L+A ++T+ + +
Sbjct: 4 ITVVDVNDNAPVFASDSYNVTILENITIPAVI-ATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAVIR----AKDGAQPALSSTVPLTINVIDINDHAPTLI--AAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFII--------DEDSGLIK--TTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE--DQKITYRIEEADREVF---SILDIGDQGAILSVSGELKRQDHK------VRVEISATDQGGLQ--GRCVVNVFIDDVN-SAPYFNDHPFSVKIPE---HSPIGYPVITLKAEDHDRGDNARIVYSIDSSQF--FRIDPSSGDISVSSDLDREDRAT-FSVIVTASDHASPPLNTST---QIEVILDDINDNSPQF---TSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSD 525 HSP 2 Score: 140.969 bits (354), Expect = 2.866e-33 Identity = 166/632 (26.27%), Postives = 287/632 (45.41%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP----FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINE 2253
++EI ++D NDN P ++ +S + ++EN + + + KA D D N +Y + +S ++ + S + LR ID + S + A DG P+ + ++ L I +ID+ND+ P ++ +++ N+ I + +++A D D N ++S+ + F ++ + +++ K L E A Y + A D G P + TT+ + LK+ N P+ N + I E G I+T DND + +E + ++ ++ + AI+S ++ ++ ++ K R++ I D G +++ I DVN ++P F + I E + + + L A D D G NA++ Y I D ++ +++ + I++ S LDRE R V A+D P + ST + + L DINDN P F + Y + ED + +V+ A D D G NG V Y + + P F+L+ SG L +DRE Q + I ARD T L +A +++ + D NDN P F + +Y + ++ PVGS V + A D D G N+ I F + LF I E
Sbjct: 1 MVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATV-KATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVT----LRERIDAKN-SPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVG-RVYAIDEDSGPNGIIKYSME----GSEDFIIDEDSGLIKTTKLLDRETTA-RYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYN--VTISEEMPRGSQIITLKAVDNDEDQKITYR---IEEADREVFSILD--IGDQGAILS-VSGELKRQDHKVRVE--ISATDQG--GLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSI-------DSSQFFRIDPSSGDISVSSDLDRED-----RATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVS---AIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDRE-QFAVIVLPIFARDRGTPSL---SAASEITLTLSDVNDNAPTF---EQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEE 585 HSP 3 Score: 90.1225 bits (222), Expect = 9.758e-18 Identity = 134/557 (24.06%), Postives = 226/557 (40.57%), Query Frame = 1
Query: 190 PSDTTKFKLIKNRFFQIENGDNL-KVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEIN-STLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRI--QWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPD 1848
P+ K+ + + F I+ L K + L+DR+ + R + N + + + D NDN P + + + + E S + L KA D+DE + Y+IE + F + ++G L + + R+ V + A D G G + + I DVN + P F ++ I + I + LK D NA + Y + F ++P + + V L E A+ + + A DH P + T + + L + N P A I E+ +G L D D G +G + + E + I ++ +L + DRE I L IF +D G P+ + ++EI++ + DVNDN+P FE+ Y I E + T+ + A D D+G NA + +RI D L+D + + +I+ D E N F F + SG Q S + V I + D+NDN P + + + F + + +R++ A DPD
Sbjct: 151 PNGIIKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARY------SLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITL-KAVDNDE--DQKITYRIEEADREVFSILDIGDQG--AILSVSGELKRQDHKVR-VEISATDQG--GLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS------QFFRIDPSSGDISVSSDLDREDRAT-FSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATIS--EDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSG----TLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFF-----ELQASSG--QLSSTVPVRIHVSDVNDNKPALKDF---VILMNRFDNVQMARQIGFIPAFDPD 669 HSP 4 Score: 86.2705 bits (212), Expect = 1.338e-16 Identity = 72/240 (30.00%), Postives = 119/240 (49.58%), Query Frame = 1
Query: 1711 VSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRET-LLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETE 2427
V I ++D+NDN PVF YN++ LE+ +A A D DFG NG V YS+ + + ++ ++GE+ + +D + P T I A+D L ++TV ++I + D ND+ P I + I L V +G V V AID+DSG N I++ +E + F I+E SG + T+ +L +L + A D G+P L + + + + N ++ F++ E
Sbjct: 2 VEITVVDVNDNAPVFASDSYNVTILENITIPA---VIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSP--ITAVIRAKDGAQPAL---SSTVPLTINVIDINDHAPTLI---AAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED---FIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDI-NDNAPTFDKKE 226
BLAST of Protocadherin alpha-11 vs. Ensembl Celegans
Match: cdh-1 (CaDHerin family [Source:UniProtKB/TrEMBL;Acc:Q5F4W0]) HSP 1 Score: 150.599 bits (379), Expect = 3.270e-36 Identity = 174/663 (26.24%), Postives = 286/663 (43.14%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI--EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDC-FDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKF---NCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCG 2340
+++ DENDN P ++ + +E+ E +L + + LP D D ++ + I + F ++S K N+ ++ L + +DRE + + + A DGG P+K G L+ I+IID NDN P+F S YT S+ N+ I S L + + ATD DI N + + + F ++ I L AS + + A DHG P S VT+ + L P + L+ N+A ++EN +G ++ V D K S L P+ D + L+ I DRE + L + G+ + I D+NDN+PQ+ H ++ N+ LTA D D G N +RY + DT L +K +I ++D ++V A D G P S V +L+D P F++A + + ED KV +A++ G + + YS+ + ++ SG + D E Q S Y ++ A ++ + +T+T +SI ++D NDN PIF +PNE Y + + + +V A D DSG ++ + + E + FSIN +GE+ L+ +G L + A D G
Sbjct: 110 VEVDDENDNAPSFADQVVKLEISEFAQLGTSF-ALPTVTDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHL-ITVQATDADIGENSRISYDIKKTSAPSNSNFAISQSGVITTTASLLP----ASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSA--HLMENSTLGSIV--ARVSIAQQYRDTKLRLIGSSALCPQQTD-----------QAHVYLLLLCGILDRETASEHHLKFLLEKDGQ--IIIEHPQLLTIGDINDNAPQWHSSQIHISL---NRTQGGSRTLTAKDPDLGQNGWIRYSV-LDTELVSIDK-----ETGRIFVPNTID-----CNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKV---VANNSQCGNSKRIRYSLQNQDEH-LTVDTMSGTVCIQKTFDFEKQKS-YQTTVIATNANS-----ETSTSLISIRLKDVNDNWPIF-YPNE--YHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS--FSINPVTGEVFAQKPLA---RGRFHLVVSAKDGG 717 HSP 2 Score: 98.2117 bits (243), Expect = 3.435e-20 Identity = 182/726 (25.07%), Postives = 307/726 (42.29%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKV-----SGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDRE--VKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIAT-DSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV-RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLT 2274
+ EN +GS++ ++S I + TK +LI + + D V G++DR E + ++ F G + L + I D NDN PQW + I I + T+ S L A+D D N Y + T +S +K I F+ ID + S + A DGG+P+ + LQ++ ++D P FE + + I + I + L +K+ A + + R+SL + ++ + + ++K+ E S Y+ ++ A + E S + +++ LK+ N P I P N + + E +L D DSG G+ + IL ++S + + I+ +T ++F ++ + R L++ KD G + SA I I +ID + +PQF + Y E+ P I + G ++++Y I + D N I E +I + LD + + + AT SGE S T V I + D NDN P F + IS ED K V A D D NG+V YSI+ +++ +G+L + L+D E Y + A D + +++ +++ I + D NDN P F +S Y +++ P ++V V A DKDS N QI + + F I+E G + T
Sbjct: 349 HLMENSTLGSIVARVS---IAQQYRDTKLRLIGSSALCPQQTDQAHVYLLLLCGILDR----ETASEHHLKFLLEKDGQIIIEHPQL----LTIGDINDNAPQWHSSQIHIS-LNRTQGGSRTL---TAKDPDLGQNGWIRYSVLDTE---LVSIDKETGRI--FVP--NTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCL-VKVVANNSQCGNSKRIRYSLQNQ---DEHLTVDTMSGTVCIQKTFDFEKQKS-YQTTVIATNANS--ETSTSLISIRLKDVNDNWP-IFYP-NEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHIL-------------SESSSFS-INPVTGEVFAQKPLARGRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSV-------GAMSKVKYSIY--SGDQDHNFSID-EDTGKIYVTRYLDADVHDTVL-----LNIQATLPSGE---SNQTQVVIFIEDHNDNPPQFSSSLVEISIREDL---KLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEAT-RNYKLRVKATDLG---IPPRSSNMTLFIHVLDVNDNAPEF---EKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSE--YFGIDEKLGNVYT 999 HSP 3 Score: 97.4413 bits (241), Expect = 5.604e-20 Identity = 180/784 (22.96%), Postives = 318/784 (40.56%), Query Frame = 1
Query: 127 IFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPF--------LKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIR--IIENQDIGVVILTGVVKDNDSGMDGK-FNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQ-----SLDREKYPNGFRFVCPYQVI--ATDSGEPQRS--GSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQP--SQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTP 2412
I E LP G I KL P + T + +++ I++ ++ G+I + L+ + I G G +++++ + NDNVP + S V EN ++ S Y+ A+D D N++ + +F+ S+ S + F + L +D E++ H +T+ A DG + T L I + D+NDN P F Y ++ KI A DLD +TY I F + P + L +K Y ++ A D+G P + V++ + P+ A R ++EN IG+ I N SG + + F+ I +P+ I +++K L DRE + + + + + + +I++D NDN P F Y+ ++ + I Q+ A D D G N ++ YRI N L V N +IQ +++PN +Q++ A D G P R+ G VS+++ + + P F Y + LED +K I G+ D ++E ++ +GEL +D E++P S Y S++ + ++A V + IV+E ++ P+F +S+Y +Q+ P G V ++AID+D G++ +++ + + + + I E +G + L V + I + SP + + +EIG F S P
Sbjct: 1841 IDEGLPRGQFIAKLQ----PELAGLT-YSIVEG---NIDSAFSVDSEGVIRTNLELDREILERYSLKVIGTG---SGQQIGTRVDVRVNNLNDNVPSFPM-SKPRRVPENLRVGS-YVATVGAKDVD----NLAPLR-------YFLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDGSFDTFT---NLTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLDARGALTYSLGQGSSSI----FRVAPESGALFMKV---LPPAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAE---PTDKPGFEKAEFRFEVMENSKIGLQI------GNLSGEESREFHYRIQDPEASKI-FSIDK-------FGRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRI------LSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPN-----ATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVGTVLQK----IRASNRLGMRNDGLLYSLKEHQGKLGIDVKTGELTLKTHLDWESEPIISMY-LSVSDGNG-------RSAVVPLKIVVEPVDEFAPVF---TKSSYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSISDRQSTV--KIEEHTGIIRLQKPL-VSRRNLTIEQITVVAYSSPTKQSKTTVYLEIGPFDVQPSLP 2544 HSP 4 Score: 93.2041 bits (230), Expect = 1.014e-18 Identity = 126/525 (24.00%), Postives = 223/525 (42.48%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHP-NNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDC-FDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSE-NIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTY-SIVRETLLPFKLNPNSGELY 1935
++ I++ D NDN P + N + V E K + L + A D D +SY+ + +S + KP + R ++ + A DGG S S + I +ID + P F S Y EI +T D+ + A ++S+ QD F ++ + V + L + + L G E ++T V + +++ N PP +++++ I +D+ + VV+ +D D K N + Y II + + E + L T + D E +L + D G P +++ + I ++DVNDN+P+FEK +Y + E + P + ++ A D D N Q+ YRI + + + E + +S+DRE + ++A D G P RS + + I ++D+NDN P + +I+ + S + +A DPD G+NG V Y + ++ +L K N G++Y
Sbjct: 626 LISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVV-SASDMDSGTFGEVSYHILSESSSFSINPVTGEVFAQKPLARGR----------FHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKY--------EIRTTEDILPGIAIGSVGAMSKVKYSIYSGD--QDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSG---ESNQTQVVIFIEDHNDNPPQF----SSSLVEISIREDLKLHEPFYVVQASDK--DKKKNGEV----RYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEYFGID-----EKLGNVYTKRSIDREVISH-----VDISIVAEDKGVPPRSSTASARISVLDVNDNPP----SCLSITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQLQSSLFVVKSN---GDVY 1099 HSP 5 Score: 92.8189 bits (229), Expect = 1.445e-18 Identity = 148/608 (24.34%), Postives = 253/608 (41.61%), Query Frame = 1
Query: 601 FLKLRRGI-DRELISWHNVTLLAVDGGTPSKTGSLQL----LIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHEC-FASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAV--IRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLED------FGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+L L GI DRE S H++ L K G + + L+ I D+NDN P + SS I +L + A D D+ N R+S+ + + ++ + V ++ +C SE +F + A D G P + V L + PP A+ + I E+ IG ++ V ++ G + S+ +N D LT++ T S + I K FD E + Q + + + +++ ISI + DVNDN P F YH T+ E +P + ++A D+D G ++ Y I ++S + N + ++ A + L R + F V V A D G S + I ++D + P F ++ Y I ED GS KV I +GD ++ F ++ ++G++Y +D + + +I A L ++ V I IED NDN P F + S +I + + + +V+A DKD N ++++ + I++ +G+L T ++L L +KA D G P ++ L I +
Sbjct: 393 YLLLLCGILDRETASEHHLKFLL------EKDGQIIIEHPQLLTIGDINDNAPQWHSS----QIHISLNRTQGGSRTLTAKDPDLGQNGWIRYSV----LDTELVSIDKETGRIFVPNTI--DCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQF----EKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSL---QNQDEHLTVD-TMSGTVCI-----QKTFDFEKQKSYQTTVIATNAN--SETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESSSFSINPV-----TGEVFAQKPLARGR----FHLV----VSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAMSKVKYSI-------YSGDQDHN--------FSIDEDTGKIYVTRYLDADVHDT-VLLNIQA-----TLPSGESNQTQVVIFIEDHNDNPPQF---SSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHV 932 HSP 6 Score: 74.7146 bits (182), Expect = 5.266e-13 Identity = 83/287 (28.92%), Postives = 128/287 (44.60%), Query Frame = 1
Query: 337 RGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKL-DSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFL-KLRRG--IDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDG 1179
+ L G +N + I I D NDN PQ+S + + I + E+ KL + FY+ +A D D+ N Y I S S+ I F +L G +D E + + + A D G P ++ ++ L I ++DVNDN P FE S+YT + N T+ K+ A D D N + YR + + F ++ + K+S+ E S SI A D G P S + + + + N PPS L + I + + I T V D D G++G
Sbjct: 810 QATLPSGESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVV--QASDKDKKKNGEVRYSI-------ISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLEN-SPPKTIVGKVVARDKDSLENGQIVYRITNGSEY-----FGIDEKLGNVYTKRSIDREVI-SHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCL---SITPIVVPAGSPLSTAIGTIVAMDPDKGLNG 1077 HSP 7 Score: 55.4546 bits (132), Expect = 3.423e-7 Identity = 81/285 (28.42%), Postives = 128/285 (44.91%), Query Frame = 1
Query: 1561 NKLIKV-ESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHD-PDFGVNGDVTYSIVRETLL-PFKLNPNS-GELYSYDLV-----DRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEK--RNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+K +KV E + +I I LD EK + F V V +SGE + + +E+ D NDN P F + E F S + D P F V+ + I++ + FKL E DLV DRE + +Y I A+D K + SI I D NDN P+F + S Y +S + +GS + V+A D D G NS+I + +++ N F+I+++ + +T S++ + + A D GSP L++ +TI +
Sbjct: 66 SKFLKVDERSGEISTIAHLDYEKR-SKFDIVA---VKVEESGE-----TIDILVEVDDENDNAPSFADQVVKLEISE-FAQLGTSFALPTVTDGDGPKFDVH---RFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFR-DKYELLIEAQDGGKPA---KIGQLRCSIEIIDANDNAPVF---SRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFAISQSG---VITTTASLLPASTHDVIVVASDHGSPSLSSSAVVTITV 327 HSP 8 Score: 55.4546 bits (132), Expect = 3.662e-7 Identity = 94/387 (24.29%), Postives = 159/387 (41.09%), Query Frame = 1
Query: 1270 LITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSI-----VRETLLPF----KLNP-NSGELYSY-----DLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQF-ILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
L+ N DRE + + +L+I +D GKPA SI IID NDN+P F + Y ++ + + A D D G N+++ Y I+ ++ + N + + I SL P V V+A+D G P S S V+I ++ + P +I +L + S AH + G + + R+T L L P + + + Y ++DRET + + +D + + + T+ D NDN P + + +I +S G TL A D D G N I++ +L+ E L SI++ +G + + E ++A D GSP L+ Q+ ++
Sbjct: 185 LVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSN--FAISQSGVITTTASL----LPASTHDVI---VVASDHGSPSLSSSAVVTITVLGSTLSSPPL-----DIIWLVESNS-----------AHLMENSTLGSIVARVSIAQQYRDTKLRLIGSSALCPQQTDQAHVYLLLLCGILDRETASEHHLKFLLEKDGQIIIEHPQLLTIG------DINDNAPQW-----HSSQIHISLNRTQGGSRTLT-AKDPDLGQNGWIRYSVLDTE----LVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADL 530
BLAST of Protocadherin alpha-11 vs. Ensembl Celegans
Match: cdh-4 (Cadherin-4 [Source:UniProtKB/TrEMBL;Acc:A0A1C3NSI5]) HSP 1 Score: 105.145 bits (261), Expect = 2.377e-22 Identity = 163/681 (23.94%), Postives = 288/681 (42.29%), Query Frame = 1
Query: 361 NNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLN---VPFIV---QDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAV--IRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKD-----FGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQ---LRYRIQWDTSLYDPNKLIKVESNCQII---AIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTN----LLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAID 2334
+++K ++++I D N++ PQ+ + S + + EN K ++ A D D N + + + + S + GI +KL + +DRE H ++A D G P + L I + DVNDN P I +L + + + A D DI N +F LN VPF + C ++ L K+ + SI+ DHG P+ T+ LH++ ++ + + ++ + EN +IG ++ +++ ++G + K LE Y II ++ T + DRE K+ + + +D + P + I I+D ND+ P +K Y ++ E + N I ++ A D DD N L ++I+ DP +++ I I+ LDREK +V D GEPQ + V + ++D NDN P F QA ++ S F K+ A D D G N +TY+I E F ++ N+G + + + + + Y ++ A D T R T + + + N P I +S+Y I +S VG V ++A D D ++ + + + +F + + +G+LL + + ++ +GE L I D
Sbjct: 701 SSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKV-TANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGI---VKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSC-MAAFDEDIGQNSKLKFLLNSEKVPFRIDHHSGCIFIHAPEYPLDYHKT-------PFFNLSIEVADHGDPI--LSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVI--MIEAKETGDEQKVKAENLE---YRIIGGDGWPHFSIDQKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERG----DPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVS-----ICDGGEPQLCSNVIVIVNVLDENDNSPTFTQAIHHYSVRSKFAG-----KLCRIFAVDADEGENARLTYNIT-EGDARFSID-NNGNIIASEAIHGD---ESYALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEISGKKSDYVIPISDADQVGLTVGKLEASDAD---GDELWWSISSGDPDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTD 1340 HSP 2 Score: 104.76 bits (260), Expect = 4.010e-22 Identity = 108/451 (23.95%), Postives = 214/451 (47.45%), Query Frame = 1
Query: 646 HNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYP----PSILLPGNNA----------VIRIIENQDIGVVILTGVVKDNDSGMDG--KFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIA-IQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIP--VFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELY 1935
+N ++A G K + I+I+D ND+ P+F + + Q+ + L +K+ ATD D N + Y+F+ +P ++N + + + K + + ++ A+D G P+ + + KN P P I+ N ++ + E+ IG V+ D D+G +G ++ + ++++ LT+++ E I + S ++ + ++ +QL + D G P ++ + + I DVN++SPQF++ Y+ I E +P I ++TA+D D G N ++++ + + + + +I +++ I+ ++SLDRE + V + +IA+D G P R T ++I + D+NDN P V Q + I ED + V+ A D D G N + + + E +PF+++ +SG ++
Sbjct: 458 YNFKVIASLHGINEKLAEKDVSIEILDSNDHAPVFSAKWMRQTPIVIGKPGDVL-VKVDATDQDEGENGKIVYKFTSELPL------EINANTGEITLVEVPKK---GNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQESENKHSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEV-LTVDEQSGE-ITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQ---EKSSVISIDAKTGIVKLLKSLDRED-----QDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIP--EDL---PHGAFVSCMAAFDEDIGQNSKLKFLLNSEK-VPFRIDHHSGCIF 882 HSP 3 Score: 92.4337 bits (228), Expect = 1.939e-18 Identity = 86/359 (23.96%), Postives = 165/359 (45.96%), Query Frame = 1
Query: 706 LLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISF 1782
L + +ID+ND P F FY+ SI + + T+ + + ATD D N + Y + F ++P + V K L+H+ + +I A D P + TTV +++ ++++ P ++ + ++E+ D+G VI G V+ ++ +D + + D L + +S +I DRE K + ++ I G + +++ I DVNDN+P F ++ +TI E+ ++ +A D DD + ++R+ + + +D N E++ + LDREK + Y++IA + E + +I + D+ND+ P F++ +NI
Sbjct: 2491 LTLSVIDINDKPPFFVLPFYSTSISESAKEGDTV-MMVSATDDDENDTIEYSL---LDGSESQFFSVHPRQGTITVAKKLEHKAGVT-LSLTIKATDSANPPHHATTTVEVNIASESVKVPR--FSNSHYLFSVMEDADVGNVI--GRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTG----KIIVKSSLDRERKNQWKMTIRADAAG--GVHAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEENPYFDLN-----ENSGWLTVASQLDREKIDH-------YKLIARATDEGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDL 2822 HSP 4 Score: 84.3445 bits (207), Expect = 5.227e-16 Identity = 193/793 (24.34%), Postives = 321/793 (40.48%), Query Frame = 1
Query: 133 ENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNRF--------FQIENGDN-LKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNL---KILEIQILDENDNVPQWS-----QNSIVIEVVEN--TKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTP-SKTGSLQLLIK-------------IIDVNDNK--PIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSL-NVPFIVQDCFDLNPFNAILRV----KKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS--LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPV--FQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLY--RKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQ---IQFILEEEKRNILFSINETSGELLTSTV--LSVIHKGEETLFIKAIDCGSPRL 2352
E P+G ++ ++ NV + P D + ++ L ++ F I + + L+VS I+R + R NF I G N K + I+ILD ND+ P +S Q IVI + K+D A D DE N YK TS+ +N G ++ + ++ SW T+ A+D G P S+ +L L+ II ++NK P+F S + + I + + K+ A D D N R+ + ++ + ++ + + V K +K + + + + A+D G PV+ S T+ L +K+ N + P + +RI EN+ G I D D G +GK S+ + +++++ I+ L+ K DRE + I D G P + ++I + DVNDN P+ + I E+ ++ + A D D G N++L++ + + + I S C I LD K P + D G+P S S + +EL+DI N F S E+ + D ++ Y I+ P G + + L+DRET+ S Y ++ ARDS T+L R+ + V I I D ND+ P+ P Y ++ P ++ V+A D D N + F +E F I+ TSG + TS + L + E L++ D G P+L
Sbjct: 394 EMAPIGRILYRM-NVNVENPDDVSLIRYSLEYSKSDLPNATLPFAIGSKNGILRVSAKINRSE-------RVYNFKVIAS---LHGINEKLAEKDVSIEILDSNDHAPVFSAKWMRQTPIVIGKPGDVLVKVD--------ATDQDEGENGKIVYKF--TSELPL--EINANTGEITLVE----VPKKGNSW-PATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQESENKHSPVFSSFPEIVEVTEDAPIGTVV-AKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVDEQSGEITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQ--FDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISIDA----KTGIVKLL--KSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLNSEKVPF----RIDHHSGCIFIHAPEYPLDYHKTP-----FFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWPHFSIDQKGTVRTTHLLDRETK-SAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKP---MYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQL 1136 HSP 5 Score: 77.7962 bits (190), Expect = 5.247e-14 Identity = 73/284 (25.70%), Postives = 136/284 (47.89%), Query Frame = 1
Query: 1657 YQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFI-----------AHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSIT-----ARDSPTNLLYRKTATVSVS-----IVIEDCNDNEPIFI-FPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEE--EKRNILFSINETSGELLTSTVLSVIHKG-----EETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNE 2421
++VIA+ G ++ VSIE++D ND+ PVF S K R+ + I A D D G NG + Y E LP ++N N+GE+ ++ + ++I +R S NL++ K T + I+ E N + P+F FP ++++ P+G++V ++A D+D+G N I++++ + + + +++E SGE+ ++ LS + K + L + AID G+P ++++ + + I + N S F+E
Sbjct: 460 FKVIASLHGINEKLAEKDVSIEILDSNDHAPVF--------------SAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYKFTSE--LPLEINANTGEITLVEVPKKGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQESENKHSPVFSSFPE----IVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVDEQSGEITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNN-HSPQFDE 722 HSP 6 Score: 77.7962 bits (190), Expect = 5.291e-14 Identity = 94/365 (25.75%), Postives = 162/365 (44.38%), Query Frame = 1
Query: 1279 NKIFDREVKTRIQLIIFCKDF-GKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYD--PNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGD-VTYSIV-----RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNY-KIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGS 2343
+++ + R Q+ + +D G+ AF+T +++ +ID+ND P F FY +I E + T+ ++A D D+ N + Y SL D ++ V I + +K + + ATDS P +TTV + + + +P F + Y S +ED V I D + ++IV ++ LPF + ++G++ +DRE + +Q+ +I A D+ + A +V++ I D NDN P F +Y + +S VG+ VT+ A+D+D + +I+F L EE N F +NE SG L ++ L L +A D G
Sbjct: 2462 SRVLNYHRDKRYQIPLVVEDATGRRAFST---LTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDE--NDTIEY------SLLDGSESQFFSVHPRQGTITVA----KKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMED-------ADVGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERK-NQWKMTIRA-DAAGGV----HAITTVTVDIGDVNDNAPAF----HGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEE--NPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEGG 2792 HSP 7 Score: 77.0258 bits (188), Expect = 1.038e-13 Identity = 95/392 (24.23%), Postives = 172/392 (43.88%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPF----NAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKN---YDIILTMNKTKSENI-AIISLITNKIFDREVKTRIQLIIFCKDF-GKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLD-DGLNAQLRY 1527
+ ++D+NDN P + +++ ++V+E+ +S EL R S N Y ++P+ F++ + GI L L + +D E +S +T++A D G P Q+ I ++D NDN P FE Y + N + + L + A D+D + L + + PF N + + +S+ +E +Y + A D GRP +S+ + +H++++N + P+ N + E + IG +L V D +DG PKN + + + + KS + + L+T K + K + L + KD GK T ++I I + ++P + + P I +L A D D + N LR+
Sbjct: 3101 VTVIDQNDNAPTFEKSTYSMKVMES---ESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNL-NAQTGI---LTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKV-LTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKI-KKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPT--FDDCNMTALVQEGEAIGHRLLKFSVSD----LDG--------PKNGAPFTVEIQGDGAKSFKVNEKLELLTAKKLEYRKKDKYLLTVIAKDVKGK---TTDCPLTIFIRQTSRHAPTMKPMKIQINTLQNELPEGIIGRLKASDEDEEDQNGLLRF 3466 HSP 8 Score: 76.6406 bits (187), Expect = 1.208e-13 Identity = 128/548 (23.36%), Postives = 230/548 (41.97%), Query Frame = 1
Query: 706 LLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLD---LKIHATDLDINANVTYRFSLNVPFIVQD---CFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQ--WDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGD-VTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYL---VPVGSLVTLVKAIDKD-SGINSQIQFIL------------EEEKRNILFSINETSGELLT 2274
+ + I ++NDN+P SID NL + +I A D D + + +R +V D F ++ N ++ V K L E + ++ A D + K T+ + + +QN P+ + ++++E++ IG + D ++ L+P + + +N I++L K D E + ++L + KD G P T A++ I ++D NDN+P+FEKE Y + E ++ + + A D+D + Y ++ +T+ P + SN ++ QS+D EK +VIA D G P + I + D ND+ P F N++ L G R + F D D NG T I + FK+N L + L R + +Y ++ A+D + KT ++I I + + P KIQ++ L +P G ++ +KA D+D N ++F L +E + LF ++ +G++ +
Sbjct: 2997 ITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDADFD-EIKFR-------MVDDFGGLFQIDDINGVVTVVKPLDSEILGF-FNLTVVASDGEF---EDKATILVTVIDQNDNAPT--FEKSTYSMKVMESESIGYELAHFRASGGDQNETIEY---YLKPSDVTSFVNLNA----QTGILTLA--KPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKK-----YNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDC--NMTALVQEGEAIGHRLLK-FSVSDLDGPKNGAPFTVEIQGDGAKSFKVNEKLELLTAKKLEYR--KKDKYLLTVIAKD-----VKGKTTDCPLTIFIRQTSRHAPTM-----KPMKIQINTLQNELPEG-IIGRLKASDEDEEDQNGLLRFGLVEGSIQSPRAQVQESRSTHLFRVDPNTGDIWS 3500 HSP 9 Score: 60.4622 bits (145), Expect = 1.020e-8 Identity = 54/180 (30.00%), Postives = 82/180 (45.56%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSD-EHPNNISYYKIEPTSKYFFISSEKSNKGIKPF-------LKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQ 891
+EI ++DENDN P++ + V +V EN+K L + KA D D EH +SY + +S ++ + PF + + + ID E I +N+ ++A DGG P L I + D ND+ P F+ T + I L LK +DLD N PF V+
Sbjct: 3202 VEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTV-KALDVDSEHFGAVSY-------ELEIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRL-LKFSVSDLDGPKN-------GAPFTVE 3365 HSP 10 Score: 51.6026 bits (122), Expect = 5.484e-6 Identity = 55/227 (24.23%), Postives = 96/227 (42.29%), Query Frame = 1
Query: 511 HPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINST------LDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKS--KTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDS 1167
H +SY K+EP +F + + + +L +L +V A+ T + +++ KII N + PIF Y +I N+ S+ L L + A D D +N + + P Q F ++ ++ +R + S E EY F + A D G+P +S + + + + ++N PP P N+ I +I GV + +D DS
Sbjct: 1599 HHGTVSY-KLEPNCTFFEVHTLSGAVHLATWLT-------KLKHRKSVECTAIVESTEGQQDIAKVIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRMLSPKDEQ-MFSVDQYSGAIRTQMSFDFEKM-KEYSFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPPR--FPSNSLDISMILPTANGVSVGGQTAQDMDS 1813
BLAST of Protocadherin alpha-11 vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 98.9821 bits (245), Expect = 2.018e-20 Identity = 176/683 (25.77%), Postives = 274/683 (40.12%), Query Frame = 1
Query: 376 LEIQILDENDNVPQW---SQNSIVIEVVENT-KLDSFYLELPKARDSDEHPNN----ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKH----ECFASEYRFSIDALDHGRP-VEKSKTTVTLH-LKNQNLYPPSILLPGNNAVIRIIENQDIGVVILT-GVVKDNDSGMDGKFNCSILEPKNYDIILTM-------NKTKSE---------NIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPN--------FTIAQLTAHDLD-DGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATD---SGEPQRSG----STTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRE--TLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSG-INSQIQFILEEEKRNILFSINETSGEL 2268
L I I D N+N P++ ++ S + +++E T K D + +A D D N YY + K F I + P + DRE +VT+ A D G G Q ++++D+NDN P FE Y S+ E T + + A D D NA +TY ++ + DL+ F + R + ++ F++ A D+G P +S VTL+ L Q P P I + EN ++ VIL V DS +N D+I + NK +S+ + ++ + D E L + D +T + + DVND PQF + + TI EE PN I + A D D DG ++ YRI + + + E +I + DREK + V A+D S P +G + V I + D+NDN P F++ Y E S+ V AHD D N + Y ++ +PF + +SG ++ + +D E QY + A D R AT +V I IED NDN P F + I+ +P ++ V A D D +S+I + LE + + +F I + SG +
Sbjct: 851 LLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVF----DRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSV-SRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDS-------------RNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATDMTSRVASTKT-FVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKID-----MYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKE---SEGEGHDVITIKAHDLDKHSN--LRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEAS-DQYHLVLIASDG------RHNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIP--KVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTI 1495 HSP 2 Score: 97.0561 bits (240), Expect = 6.470e-20 Identity = 178/695 (25.61%), Postives = 290/695 (41.73%), Query Frame = 1
Query: 370 KILEIQILDENDNVPQWS----QNSIVIEVVENTKLDSFY---LELPKARDSD-EHPNNISYYKI-----EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGS-------LQLLIKIIDVNDNKPIFESSFYTQSI-DCNLEINSTLDLKIHATDLDINANVTYRF----SLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRI---QLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQP----NFTIAQLTAHDLDDGL--NAQLRYRIQWDTSLYDPNKLIKVESNC-QIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDV-TYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLY----RKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAID 2334
K +++ D ND VPQ++ +I E+ N L+ + KA D+D + P N +Y+I +K+F I ++ I P K DRE I + +T+ A D + G+ +++ I I DVNDN P FE Y + + E + + +K H DLD ++N+ Y +PF V+ + + VK+ L E + +Y + A D GR + T V +H+++ N P A I E+ DI V+ D D LE + D + + K I L+ K DR+ + ++ D A++ + + D+NDNSP F + + Y I E +P + A D DD NA + Y I + L + + +++ N +I A++SLDRE + F+ +V A D G P R G V+I++ D+NDN P F++ Y S E + V F A D D +V TY + E+ F + + S V R QP Y +T RD + R A +V + + D ND+ P E + VP G+ + A D+D+G ++ + + + + F+I++ G L + L L I+A D
Sbjct: 1195 KTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRI--DELTGEIFPNEKF----DREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAH--DLDKHSNLRYHLIGAGGGRIPFGVRTD------SGTIFVKEPLDFEA-SDQYHLVLIASD-GR--HNATTNVYIHIEDVNDNAPQ-FEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYS----GTIELV--KALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPERLFGY-IEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRN-KLINGESVFRIDQNTGKIFAMRSLDRE-ISSEREFII--EVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEE---TAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDY-FYVTTDKDSKQSSVGVLRVKQPLDYE-DVTQRDGFHLGIRVSDGRHDAEAAVHVALVDRNDHAPHIHGATEHRVRED----VPRGTSIGRYTATDRDAGDTARFRINRQSDPKR-QFTIDQ-DGTLRVAHTLDREDIAVYNLIIEAYD 1848 HSP 3 Score: 86.2705 bits (212), Expect = 1.308e-16 Identity = 140/591 (23.69%), Postives = 246/591 (41.62%), Query Frame = 1
Query: 541 EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASE---YRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPS-ILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNK-TKSENIAIISLI--TNKIFDREVKTRIQLIIFCKDFG------KPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNF-----TIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS---LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFY--NISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP---------FKL-NPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL 2214
E +K+F I + GI +L D L H + + A + ++ + L I+I DVNDN P F YT + ++ +N T+ LK+ A D D N +S++ F +N N + K L + YRF++ A DHG PV S + + +H++ +N S + LP + + E+ G ++ +D D + S ++ KN MN + E+ ++ L + E + I L + +D G + A + I I DVN+N P+F + I + + + TI ++ A D D N + Y + + S + K ++ ++ DRE P V ATD G+ G S+E++DINDN P F++ Y ++S E G+ V A D D N ++TYS+ +T F+L N SGE+ + +TQ ++ F++ A D+ + +A V+++++ D P + + I + V + ++ +A+ NS + + L
Sbjct: 579 EDETKWFRIDP---STGIIHLTRLLDFDDPALPKLHKLKVTARED---NRESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTI-LKVTAVDKDTGDNSRITYSVD-----NHNFSINS-NGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAM-IHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADR---DEVTYSFMD-KNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQS--ESRKAFVIDRQTGVLTPSPHVVFDRETRPRE-----DVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGT-----SVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQ--KFIFNVIADDNGIPEALQSSAQVTLNVL--DKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKL 1135 HSP 4 Score: 73.1738 bits (178), Expect = 1.200e-12 Identity = 102/390 (26.15%), Postives = 168/390 (43.08%), Query Frame = 1
Query: 1390 DVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEP-QRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV------RETLLPFKLNPNSGEL---YSYDLVDRETQPSQYTFSITARDSPTNLLY---RKTATVSVSIVIEDCNDNEPIFIFPNESNYK-----IQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL---EEEKRNILFSINETSGELLTS--TVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIVGIILGTFF 2490
DVNDN P F + Y + E+ N TI ++TA D D G N+++ Y + N + SN +I A LD ++ N FV + V A D GEP S S + I + ND VF +F+ + + V A D D +VTYS + + + F ++ ++G + + D + ++ +D + +Y T+ ++ I IED N+N+P FP+ + Y ++ +Y ++V V+A D DS N I + L + E R F I+ +G L S V + E + +KA D G L Q ++E+ + D++P E S+ + + F VG + T F
Sbjct: 634 DVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVD--------NHNFSINSNGEISAKVRLDADQL-NERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAE--DAQGGTPVIQIQARDAD---RDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKP--EFPDCAKYSDIAKIMEGTYKTDPPTIVK-VEATDDDSSANGDIVYSLYYTQSESRK-AFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDIN--DNSPQFE-RPSYETSVSRFEAVGTSVITVF 1002 HSP 5 Score: 59.6918 bits (143), Expect = 1.522e-8 Identity = 118/495 (23.84%), Postives = 196/495 (39.60%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQN--SIVIEVVENTKLDSFYLELPKARDSDEHPN---NISYYKIEP---TSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHN--VTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINA--NV-TYRFSLNVP--FIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSID-ALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSIL-EPK-----NYDIILTMNKT-KSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYT-----IFEENQP--NFTIAQLTAHDLDDG---------LNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDN 1743
+++ + D NDN P + + + E E D Y +ARD D+ NI Y + + F + + K + R +DRE+ S + + A D G PS+ G + IK+ D+NDN P FE + Y S++ I + + + A D D A NV TY+ S ++ D +LRVK+ L +E F + + GR ++ V + L ++N + P I + R+ E+ G I D D+G +F + +PK + D L + T E+IA+ +LI + R + ++ + DVNDN P+ YT IF EN P ++ A D D ++ +Y Q+ +++ N + I +Q DRE G P ++A +G R +V + + D+NDN
Sbjct: 1532 VQVNVRDINDNSPIFPERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGK-----IFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAV-MSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGR--HDAEAAVHVALVDRNDHAPHIHGATEH---RVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQDGTLRVAHTLDREDIAVYNLIIEAYDNSNNIGRQMVAVYLQ------------------DVNDNGPE------PYTVPRPCIFRENTPVNQLGTCEIRATDRDTAEFGPPFTMEVSPSFKYS-QYLNVIFNANG-DGGNGSMTITPLQEFDREAPVPGKILEIPL-ILADRAG---RRNEASVHVIIGDLNDN 1985
BLAST of Protocadherin alpha-11 vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0078045) HSP 1 Score: 225.713 bits (574), Expect = 3.379e-59 Identity = 201/681 (29.52%), Postives = 328/681 (48.16%), Query Frame = 1
Query: 364 NLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEP--TSKYFFISSEKSNKGIKPF-LKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNV-PFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI--LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR--ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSL-----VTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGEL--LTSTVLSVIHKGEETLFIKAIDCGSPRLTA 2358
N+++L + + DENDN P + Q S+ IE ENT + LP ARD D P N Y I + F +SS + G+ L++ +DRE +++ + A+DGGTP G + + I I DVNDN+PIF S Y ++ N + +++ L+++A+D D + N +++N + F ++P + + K+L E + + A DHG ++ V++ + + N P+I + ++A +I E+ G + V D DS + L + LT T+ +I ++ I + DRE+ + L + D G P + S I + I DVNDN P+FE++ YH + E P ++ Q+ AHD D+GLN+ L Y + + + +++ +I +S +D E P V V+A D G P S + TV + + D+NDN P+F Q+FYN+S E+ + KV+ A DPD GVN V Y+I + L F++ SGE+ +D E + S Y F + A D + T + + + D NDN P+F +P E YK+ L S + V A D D G Q+ + + +F I+ ++GE+ + +LSV + L I A D G+ R A
Sbjct: 157 NIRVL-VTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLP-ARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSV-LQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFET-KELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALT---TRDNSIYLV--IVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETH--AQWFQIDPQTGLITTRSHIDCETEP-----VPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVS---ASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERR-SSYEFPVLATDRGG-----LSTTAMIKMQLTDVNDNRPVF-YPRE--YKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNA 809 HSP 2 Score: 183.726 bits (465), Expect = 3.343e-46 Identity = 186/697 (26.69%), Postives = 302/697 (43.33%), Query Frame = 1
Query: 355 GTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELP----KARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHAT-DLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRI--------QWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP----FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL---EEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
G + ++++Q+ D NDN P + + + E+ K S P A D D Y+I ++ ++S I F+ + H + + A DGG + + IID PIFE + Y + ++ + + I A+ D+ + V Y P F + + +R+ K L HE S+ +I A G P T V + +++ N P + I + E+ ++G + D DSG G+ S+++ + ++ LI ++ D E R LI+ D G P+ +T+ I + + DVNDN P FEK+ Y + E N I Q+ A DLD G NA++ YRI S D ++ + N I +++ LDRE R V+ATD+G P T V + ++D NDN P FQ++ Y E+ + V V A D D G N + YS LLP F+++P +GE+ + + +DRE + Y + ARD T + ++A V V I + D NDN P P E ++ P G+ V V+A+D+D G N+ I + + + + LFSI+ TSG + T VL + L + A D G+P ++ L +E+
Sbjct: 694 GLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEI--FVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDP---DGYFSIETNSGNIRIAKPLDHEA-KSQVLLNIQAT-LGEPPVYGHTQVNIEVEDVNDNAPE--FEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGH-------LILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRET-----RDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENL---RRGSVVGVVTASDLDLGENAAIRYS-----LLPINSSFQVHPVTGEISTREPLDRELR-ELYDLVVEARDQGTPV---RSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQ--PPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEV 1355 HSP 3 Score: 174.096 bits (440), Expect = 2.759e-43 Identity = 228/809 (28.18%), Postives = 358/809 (44.25%), Query Frame = 1
Query: 214 LIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLK----ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPF--------LKLRRGIDRELISWHNVTLLAVDGG---TPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDL-----KIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSL--KHECFASEYRFS--IDALDHGRPVEKSKTTVTLHLKNQNLY--PPSILLPGNNAVIR--IIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTM-NKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTS-----------------------AEXXXXXXDVNDNSPQFE-KEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQ-RSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIF-IFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNI--LFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPF----NETEESFLSDQA 2451
LI+ F + NL V+ L+DR+ E F R + +NN + ++I++ D NDN P+W Q+ I ++V E T + + A D+D N Y++ +YF +E + + F L L+ +D E + + + + A+D T S+ + ++I+D ND+ P F S + +L I+ + I A D D N +TY + + F +N I+ + KSL E RF+ I A DHG+P E K+++ LHL Q + PP L AV R I+EN G +L K + G N ++ +Y+I + N + + T FDRE + L ++ +D + + +S A I I + DVNDNSP+F Y ++ E ++P I + A DLD+G NA L Y I T NK ++S+ ++ + LDRE++ R+ Q+ A+D G+P+ R G ++I + D NDN P F+ + Y S ED V A D D GVN + YS+ ET F ++ SG + + +DRE Q S Y F + A D ++ATV V I + D NDN PIF +P Y Q+ L+ G + V+A+D D G N++I + L E + F IN ++G L S L+ L + A D G+P +++ + + IGE P TP NET L + +
Sbjct: 1421 LIEAAFDIDRHSGNLVVARLLDREVQSE--------FRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNF-TATDADTGTNGDLQYRL---IRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNG---EGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQP-EPKKSSLNLHLIVQGSHNNPPRFL----QAVYRATILENVPSGSFVLQVTAK----SLHGAENANL----SYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLDEGPNADLIYSI---TGGNLGNKF-SIDSSSGELSARPLDREQHS---RYTL--QIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQED---APLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQAS-YNFMVLATDG--GRYEVRSATVPVQINVLDINDNRPIFERYP----YIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEA--PQGTPVLRFQNETYRVMLKENS 2179 HSP 4 Score: 152.14 bits (383), Expect = 1.702e-36 Identity = 191/717 (26.64%), Postives = 310/717 (43.24%), Query Frame = 1
Query: 367 LKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLEL-PKARDSDEHPNNIS--------YYKIEPTSK-----YFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVD--GGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIH---ATDLD--INANVTYRFSLNVPFI------VQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPV-EKSKTTVTLHLK--NQNLYPPSILLP----GNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSA-EXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQV--------IATDSGEPQRSGST-------------TVSIELMDINDNIPVFQQAF-YNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLL-PFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCG 2340
+++L +++LD NDN P ++ +S+V V E+ L + P R +D N++ Y + P +K F I N L + R +DRE+ S + + A+D ++ ++ + I++ DVNDN P + ID + + + IH ATD D N ++ YR P + F ++ L ++ L E EY + ALD V E+ +T+VT+ L+ + N + P + P G A + I + IG V+ V D DSG +G+ I N + +N +++ I ++ + D E R LII KD G+P S+ + +I+ ++N P+F + Y TI E + Q+TA L NA L Y I + N L V+ II + DRE + +V P V +++ + QRS + T+ I + D+NDN P F+ Y +S E+ + +A D D G N D+ YSI L F ++ +SGEL + L DRE Q S+YT I A D + +++I +ED NDN P F S Y + P+G+ V + A+D D G+N+++ + L E + F+I+ SG + T L + + A D G
Sbjct: 1348 VRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGN------LVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAP----EWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAV-QEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITG-GNGEGRFRIN-SQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVA----NDLFHVDWQRGIITTRGQFDRESQAS---YVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPEN----SEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSARPL-DRE-QHSRYTLQIQASDR--GQPKSRQGHCNITIFVEDQNDNAPRFKL---SKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQ-WQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGG 2032 HSP 5 Score: 148.288 bits (373), Expect = 2.218e-35 Identity = 162/620 (26.13%), Postives = 282/620 (45.48%), Query Frame = 1
Query: 604 LKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIF-ESSFYTQ-SIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAI-------LRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAII-------SLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQ----FEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLN-AQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQ-SLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLE--DFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR--ETLLP-FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNIL-FSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAI--QQLT 2373
++ + +DRE + +++ + + G ++++L+ + D NDN P F ++S + + + E+ TL + A DLD+ T R+++ V V D F L+ L++ L E Y I+ALD G P + TV + +++ N P + + + EN +G +L D D+ +G +I N+ +S+ + ++ NK D E K +L++ KD G+ T+A +SI + DVNDN P F + I E QP +A+++ HD D A + + + L +++ ++ + LDRE N V+ATD G P S ++ + + D+NDN P F+Q Y+ + +E D G+ V +AHD D G+N +TYS+ ET F+++P +G + + +D ET+P ++ ARD L ++T +V + I D NDNEPIF ++S Y + ++ PVG + V A D D G+N+ + + + E +++ F + SGE+ + L + + A D G TA+ QLT
Sbjct: 132 IRTKVKLDRETRASYSLVAIPLSGR------NIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTL---LPARDLDLEPYNTQRYNI-VSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPG-YSLLIEALDGGTPPLRGFMTVNITIQDVNDNQP--IFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAI------------NRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHF---ALTTRDNSIYLVIVHLPLDREIVSN-----YTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGT-----SVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVP-QLTVVARDGGVPPL---SSTATVLVTIHDVNDNEPIF---DQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLT 706 HSP 6 Score: 143.665 bits (361), Expect = 5.780e-34 Identity = 181/733 (24.69%), Postives = 308/733 (42.02%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGT-PSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVP-FIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSE---------------NIAIISLITNKIFDREV------------KTRIQLIIFCKDFG-------------------KPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVF-QQAFYNISFLEDFGSKKNSRKVAVFIAHDPD------FGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTL------VKAIDKDS-GINSQIQFILEEEKRNILFSINETSGEL---LTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIE 2379
+ I + D+NDN P++ + V E+ L + +++ A D+D N Y + +++ F +S + +DREL + +N +LA DGG ++ ++ + I ++D+NDN+PIFE Y + ++ TL LK+ A D D+ AN +SLN V F +NP L +SL E + A D G P + S + L + P + + + EN G +L V +D G K S N D IL+++ E ++ +L + E TR Q + F P + AE+ I + D NDNSP+F ++ + T+ E N +AQ+ A D D G NA+LRY I +D +I+ + + LDRE R + ++IATD G PQ +G+ T+ ++++D+NDN P F +S + G+ + A+D D + + + T I E + F L+ SG+L +D E Q +Y + A D+ A +++ + D NDN P+F+ Y L + + +++ V A D DS G NS++ +I+E + FS++ ++G + ++ +V G+ + I A D G P L + L ++
Sbjct: 1938 ITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQI-SAVDADLGVNARLVYSLANETQWQFAIDGQSG-----LITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTL-LKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASES-GKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFS-FGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGN--HDNAFVIEPAFSGIVRTNIVLDRE-----IRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEATELGA-----VITSISANDVDTYPALTYRLGAESTVDI--ENMSIFALDRYSGKLVLKRRLDYELQ-QEYELDVIASDAA------HEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEG--FSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQ 2637 HSP 7 Score: 116.701 bits (291), Expect = 1.007e-25 Identity = 174/729 (23.87%), Postives = 309/729 (42.39%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPN-NISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDC--FDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQN--------LYPPS--ILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDI-ILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREK---YPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR---ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVS---IVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL----EEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIVGIILG 2481
L I++ DENDN P++SQ V V E +F ++ A DSD N + Y+ ++ F+ E + GI ++ +DRE+ + + ++A D G P TG+ + ++I+DVNDN+P F + ++ E+ + + I A D+D +TYR +++ F L+ ++ L +K+ L +E EY + A D +++T +T+ + ++N PP+ +LP A+ I E+ + +LT D DS + I+EP + N S N++ + + D V+ I KD GKPA +S + + D QF + Y I E + QL D L+ L + S ++ L++ ++ I+ ++ LDRE+ Y R V + S +V I ++D NDN P+F ++ + + + + S I D + N +V Y I E + F ++ +G L+ + +D ++ Y I A DS + + S+ + + D NDNEP F + Y L+ PVGS V A D D G Q+ + + +E +F ++ SG + ++ V + + + A D G + + ++ IE + P F E F+ A + G ++G
Sbjct: 2308 LVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQV-HAFDSDAGSNARLRYHIVDGNHDNAFVI-EPAFSGI---VRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLV-TVSEATELGAVI-TSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYE-LQQEYELDVIASD---AAHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILP---AISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVR------IIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLG----QDALDQSLAIIAGNEESAFE---LLQSKA---IVLVKPLDRERNDLYK--LRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHM--FTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDS-----HHQRPLCSLQPFRLELHDENDNEPKFPL---TEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQ---FTERTYRFVLPAAVALPQGYVVG 2991 HSP 8 Score: 113.235 bits (282), Expect = 1.001e-24 Identity = 152/664 (22.89%), Postives = 286/664 (43.07%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKP-IFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAII--------SLITNKIFDREVKTRIQLIIFCKDFGKP--AFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRI-----QWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPY----QVIATDSGEPQR-SGSTTVSIELMDINDNIPVFQQAFYNIS-----FLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSYDLVDRETQ----PSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLT 2274
+++LD NDN P++ ++ + EN + S + + A D D N Y + P + F + + + R +DREL +++ + A D GTP ++ + + I + DVNDN P I + S+ + + +++ A D D NA++TY F ++P + ++R + L HE S YR + A D G P ++ + + + + N P+ ++ V R+ E+ +G V+ G + + D N ++ + T+N + I +L+ ++ DREV++ +L I D +++ + I + DVNDN+P++ ++ + E I TA D D G N L+YR+ Q + S L +++S +++Q+ P F V Y Q + S +R S TV + ++D ND+ P F + F+ D + + VA +A D D G NG +TY I F++N +G + + T+ ++ I A+D K +++++ ++++ ++N P F+ ++ Y+ + VP GS V V A N+ + + + N LF ++ G + T
Sbjct: 1141 VRVLDANDNDPKFQKSKYEFRIEENLRRGSV-VGVVTASDLDLGENAAIRYSLLPINSSFQVHP------VTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEV-VRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEE-RSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFT--SSSLVFRVREDAALGHVV--GSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQA------PLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISD--ATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDH--GQPEPKKSSLNLHLIVQGSHNNPPRFL---QAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITT 1778 HSP 9 Score: 58.151 bits (139), Expect = 5.767e-8 Identity = 75/263 (28.52%), Postives = 115/263 (43.73%), Query Frame = 1
Query: 1711 VSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL-LPFKLNPN---SGELYSYDL-----VDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL--EEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEES----FLSDQAT 2454
V + + D NDN P F Q +I F E+ K + A D D Y+IV + F+L+ + G LY DL +DRET P Y+ I A D T L ++V+I I+D NDN+PIF N+S Y + VG+ V V A D D+ N +++ + + + +F I+ +G + + L K L + A D G L ++I + T N+ + + FLSD A+
Sbjct: 160 VLVTVKDENDNAPTFPQTSMHIEFPEN---TPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLY-LDLQISGFLDRETTPG-YSLLIEALDGGTPPL---RGFMTVNITIQDVNDNQPIF---NQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRV--------TDVNDNQPTINVIFLSDDAS 403
BLAST of Protocadherin alpha-11 vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0343249) HSP 1 Score: 225.713 bits (574), Expect = 3.379e-59 Identity = 201/681 (29.52%), Postives = 328/681 (48.16%), Query Frame = 1
Query: 364 NLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEP--TSKYFFISSEKSNKGIKPF-LKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNV-PFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI--LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR--ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSL-----VTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGEL--LTSTVLSVIHKGEETLFIKAIDCGSPRLTA 2358
N+++L + + DENDN P + Q S+ IE ENT + LP ARD D P N Y I + F +SS + G+ L++ +DRE +++ + A+DGGTP G + + I I DVNDN+PIF S Y ++ N + +++ L+++A+D D + N +++N + F ++P + + K+L E + + A DHG ++ V++ + + N P+I + ++A +I E+ G + V D DS + L + LT T+ +I ++ I + DRE+ + L + D G P + S I + I DVNDN P+FE++ YH + E P ++ Q+ AHD D+GLN+ L Y + + + +++ +I +S +D E P V V+A D G P S + TV + + D+NDN P+F Q+FYN+S E+ + KV+ A DPD GVN V Y+I + L F++ SGE+ +D E + S Y F + A D + T + + + D NDN P+F +P E YK+ L S + V A D D G Q+ + + +F I+ ++GE+ + +LSV + L I A D G+ R A
Sbjct: 157 NIRVL-VTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLP-ARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSV-LQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFET-KELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALT---TRDNSIYLV--IVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETH--AQWFQIDPQTGLITTRSHIDCETEP-----VPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVS---ASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERR-SSYEFPVLATDRGG-----LSTTAMIKMQLTDVNDNRPVF-YPRE--YKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNA 809 HSP 2 Score: 183.726 bits (465), Expect = 3.343e-46 Identity = 186/697 (26.69%), Postives = 302/697 (43.33%), Query Frame = 1
Query: 355 GTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELP----KARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHAT-DLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRI--------QWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP----FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL---EEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
G + ++++Q+ D NDN P + + + E+ K S P A D D Y+I ++ ++S I F+ + H + + A DGG + + IID PIFE + Y + ++ + + I A+ D+ + V Y P F + + +R+ K L HE S+ +I A G P T V + +++ N P + I + E+ ++G + D DSG G+ S+++ + ++ LI ++ D E R LI+ D G P+ +T+ I + + DVNDN P FEK+ Y + E N I Q+ A DLD G NA++ YRI S D ++ + N I +++ LDRE R V+ATD+G P T V + ++D NDN P FQ++ Y E+ + V V A D D G N + YS LLP F+++P +GE+ + + +DRE + Y + ARD T + ++A V V I + D NDN P P E ++ P G+ V V+A+D+D G N+ I + + + + LFSI+ TSG + T VL + L + A D G+P ++ L +E+
Sbjct: 694 GLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEI--FVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDP---DGYFSIETNSGNIRIAKPLDHEA-KSQVLLNIQAT-LGEPPVYGHTQVNIEVEDVNDNAPE--FEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGH-------LILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRET-----RDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENL---RRGSVVGVVTASDLDLGENAAIRYS-----LLPINSSFQVHPVTGEISTREPLDRELR-ELYDLVVEARDQGTPV---RSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQ--PPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEV 1355 HSP 3 Score: 174.096 bits (440), Expect = 2.759e-43 Identity = 228/809 (28.18%), Postives = 358/809 (44.25%), Query Frame = 1
Query: 214 LIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLK----ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPF--------LKLRRGIDRELISWHNVTLLAVDGG---TPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDL-----KIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSL--KHECFASEYRFS--IDALDHGRPVEKSKTTVTLHLKNQNLY--PPSILLPGNNAVIR--IIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTM-NKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTS-----------------------AEXXXXXXDVNDNSPQFE-KEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQ-RSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIF-IFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNI--LFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPF----NETEESFLSDQA 2451
LI+ F + NL V+ L+DR+ E F R + +NN + ++I++ D NDN P+W Q+ I ++V E T + + A D+D N Y++ +YF +E + + F L L+ +D E + + + + A+D T S+ + ++I+D ND+ P F S + +L I+ + I A D D N +TY + + F +N I+ + KSL E RF+ I A DHG+P E K+++ LHL Q + PP L AV R I+EN G +L K + G N ++ +Y+I + N + + T FDRE + L ++ +D + + +S A I I + DVNDNSP+F Y ++ E ++P I + A DLD+G NA L Y I T NK ++S+ ++ + LDRE++ R+ Q+ A+D G+P+ R G ++I + D NDN P F+ + Y S ED V A D D GVN + YS+ ET F ++ SG + + +DRE Q S Y F + A D ++ATV V I + D NDN PIF +P Y Q+ L+ G + V+A+D D G N++I + L E + F IN ++G L S L+ L + A D G+P +++ + + IGE P TP NET L + +
Sbjct: 1421 LIEAAFDIDRHSGNLVVARLLDREVQSE--------FRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNF-TATDADTGTNGDLQYRL---IRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNG---EGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQP-EPKKSSLNLHLIVQGSHNNPPRFL----QAVYRATILENVPSGSFVLQVTAK----SLHGAENANL----SYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLDEGPNADLIYSI---TGGNLGNKF-SIDSSSGELSARPLDREQHS---RYTL--QIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQED---APLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQAS-YNFMVLATDG--GRYEVRSATVPVQINVLDINDNRPIFERYP----YIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEA--PQGTPVLRFQNETYRVMLKENS 2179 HSP 4 Score: 152.14 bits (383), Expect = 1.702e-36 Identity = 191/717 (26.64%), Postives = 310/717 (43.24%), Query Frame = 1
Query: 367 LKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLEL-PKARDSDEHPNNIS--------YYKIEPTSK-----YFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVD--GGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIH---ATDLD--INANVTYRFSLNVPFI------VQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPV-EKSKTTVTLHLK--NQNLYPPSILLP----GNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSA-EXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQV--------IATDSGEPQRSGST-------------TVSIELMDINDNIPVFQQAF-YNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLL-PFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCG 2340
+++L +++LD NDN P ++ +S+V V E+ L + P R +D N++ Y + P +K F I N L + R +DRE+ S + + A+D ++ ++ + I++ DVNDN P + ID + + + IH ATD D N ++ YR P + F ++ L ++ L E EY + ALD V E+ +T+VT+ L+ + N + P + P G A + I + IG V+ V D DSG +G+ I N + +N +++ I ++ + D E R LII KD G+P S+ + +I+ ++N P+F + Y TI E + Q+TA L NA L Y I + N L V+ II + DRE + +V P V +++ + QRS + T+ I + D+NDN P F+ Y +S E+ + +A D D G N D+ YSI L F ++ +SGEL + L DRE Q S+YT I A D + +++I +ED NDN P F S Y + P+G+ V + A+D D G+N+++ + L E + F+I+ SG + T L + + A D G
Sbjct: 1348 VRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGN------LVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAP----EWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAV-QEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITG-GNGEGRFRIN-SQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVA----NDLFHVDWQRGIITTRGQFDRESQAS---YVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPEN----SEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSARPL-DRE-QHSRYTLQIQASDR--GQPKSRQGHCNITIFVEDQNDNAPRFKL---SKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQ-WQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGG 2032 HSP 5 Score: 148.288 bits (373), Expect = 2.218e-35 Identity = 162/620 (26.13%), Postives = 282/620 (45.48%), Query Frame = 1
Query: 604 LKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIF-ESSFYTQ-SIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAI-------LRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAII-------SLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQ----FEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLN-AQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQ-SLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLE--DFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR--ETLLP-FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNIL-FSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAI--QQLT 2373
++ + +DRE + +++ + + G ++++L+ + D NDN P F ++S + + + E+ TL + A DLD+ T R+++ V V D F L+ L++ L E Y I+ALD G P + TV + +++ N P + + + EN +G +L D D+ +G +I N+ +S+ + ++ NK D E K +L++ KD G+ T+A +SI + DVNDN P F + I E QP +A+++ HD D A + + + L +++ ++ + LDRE N V+ATD G P S ++ + + D+NDN P F+Q Y+ + +E D G+ V +AHD D G+N +TYS+ ET F+++P +G + + +D ET+P ++ ARD L ++T +V + I D NDNEPIF ++S Y + ++ PVG + V A D D G+N+ + + + E +++ F + SGE+ + L + + A D G TA+ QLT
Sbjct: 132 IRTKVKLDRETRASYSLVAIPLSGR------NIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTL---LPARDLDLEPYNTQRYNI-VSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPG-YSLLIEALDGGTPPLRGFMTVNITIQDVNDNQP--IFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAI------------NRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHF---ALTTRDNSIYLVIVHLPLDREIVSN-----YTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGT-----SVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVP-QLTVVARDGGVPPL---SSTATVLVTIHDVNDNEPIF---DQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLT 706 HSP 6 Score: 143.665 bits (361), Expect = 5.780e-34 Identity = 181/733 (24.69%), Postives = 308/733 (42.02%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGT-PSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVP-FIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSE---------------NIAIISLITNKIFDREV------------KTRIQLIIFCKDFG-------------------KPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVF-QQAFYNISFLEDFGSKKNSRKVAVFIAHDPD------FGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTL------VKAIDKDS-GINSQIQFILEEEKRNILFSINETSGEL---LTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIE 2379
+ I + D+NDN P++ + V E+ L + +++ A D+D N Y + +++ F +S + +DREL + +N +LA DGG ++ ++ + I ++D+NDN+PIFE Y + ++ TL LK+ A D D+ AN +SLN V F +NP L +SL E + A D G P + S + L + P + + + EN G +L V +D G K S N D IL+++ E ++ +L + E TR Q + F P + AE+ I + D NDNSP+F ++ + T+ E N +AQ+ A D D G NA+LRY I +D +I+ + + LDRE R + ++IATD G PQ +G+ T+ ++++D+NDN P F +S + G+ + A+D D + + + T I E + F L+ SG+L +D E Q +Y + A D+ A +++ + D NDN P+F+ Y L + + +++ V A D DS G NS++ +I+E + FS++ ++G + ++ +V G+ + I A D G P L + L ++
Sbjct: 1938 ITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQI-SAVDADLGVNARLVYSLANETQWQFAIDGQSG-----LITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTL-LKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASES-GKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFS-FGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGN--HDNAFVIEPAFSGIVRTNIVLDRE-----IRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEATELGA-----VITSISANDVDTYPALTYRLGAESTVDI--ENMSIFALDRYSGKLVLKRRLDYELQ-QEYELDVIASDAA------HEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEG--FSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQ 2637 HSP 7 Score: 116.701 bits (291), Expect = 1.007e-25 Identity = 174/729 (23.87%), Postives = 309/729 (42.39%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPN-NISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDC--FDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQN--------LYPPS--ILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDI-ILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREK---YPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR---ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVS---IVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL----EEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIVGIILG 2481
L I++ DENDN P++SQ V V E +F ++ A DSD N + Y+ ++ F+ E + GI ++ +DRE+ + + ++A D G P TG+ + ++I+DVNDN+P F + ++ E+ + + I A D+D +TYR +++ F L+ ++ L +K+ L +E EY + A D +++T +T+ + ++N PP+ +LP A+ I E+ + +LT D DS + I+EP + N S N++ + + D V+ I KD GKPA +S + + D QF + Y I E + QL D L+ L + S ++ L++ ++ I+ ++ LDRE+ Y R V + S +V I ++D NDN P+F ++ + + + + S I D + N +V Y I E + F ++ +G L+ + +D ++ Y I A DS + + S+ + + D NDNEP F + Y L+ PVGS V A D D G Q+ + + +E +F ++ SG + ++ V + + + A D G + + ++ IE + P F E F+ A + G ++G
Sbjct: 2308 LVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQV-HAFDSDAGSNARLRYHIVDGNHDNAFVI-EPAFSGI---VRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLV-TVSEATELGAVI-TSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYE-LQQEYELDVIASD---AAHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILP---AISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVR------IIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLG----QDALDQSLAIIAGNEESAFE---LLQSKA---IVLVKPLDRERNDLYK--LRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHM--FTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDS-----HHQRPLCSLQPFRLELHDENDNEPKFPL---TEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQ---FTERTYRFVLPAAVALPQGYVVG 2991 HSP 8 Score: 113.235 bits (282), Expect = 1.001e-24 Identity = 152/664 (22.89%), Postives = 286/664 (43.07%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKP-IFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAII--------SLITNKIFDREVKTRIQLIIFCKDFGKP--AFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRI-----QWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPY----QVIATDSGEPQR-SGSTTVSIELMDINDNIPVFQQAFYNIS-----FLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSYDLVDRETQ----PSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLT 2274
+++LD NDN P++ ++ + EN + S + + A D D N Y + P + F + + + R +DREL +++ + A D GTP ++ + + I + DVNDN P I + S+ + + +++ A D D NA++TY F ++P + ++R + L HE S YR + A D G P ++ + + + + N P+ ++ V R+ E+ +G V+ G + + D N ++ + T+N + I +L+ ++ DREV++ +L I D +++ + I + DVNDN+P++ ++ + E I TA D D G N L+YR+ Q + S L +++S +++Q+ P F V Y Q + S +R S TV + ++D ND+ P F + F+ D + + VA +A D D G NG +TY I F++N +G + + T+ ++ I A+D K +++++ ++++ ++N P F+ ++ Y+ + VP GS V V A N+ + + + N LF ++ G + T
Sbjct: 1141 VRVLDANDNDPKFQKSKYEFRIEENLRRGSV-VGVVTASDLDLGENAAIRYSLLPINSSFQVHP------VTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEV-VRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEE-RSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFT--SSSLVFRVREDAALGHVV--GSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQA------PLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISD--ATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDH--GQPEPKKSSLNLHLIVQGSHNNPPRFL---QAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITT 1778 HSP 9 Score: 58.151 bits (139), Expect = 5.767e-8 Identity = 75/263 (28.52%), Postives = 115/263 (43.73%), Query Frame = 1
Query: 1711 VSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL-LPFKLNPN---SGELYSYDL-----VDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL--EEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEES----FLSDQAT 2454
V + + D NDN P F Q +I F E+ K + A D D Y+IV + F+L+ + G LY DL +DRET P Y+ I A D T L ++V+I I+D NDN+PIF N+S Y + VG+ V V A D D+ N +++ + + + +F I+ +G + + L K L + A D G L ++I + T N+ + + FLSD A+
Sbjct: 160 VLVTVKDENDNAPTFPQTSMHIEFPEN---TPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLY-LDLQISGFLDRETTPG-YSLLIEALDGGTPPL---RGFMTVNITIQDVNDNQPIF---NQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRV--------TDVNDNQPTINVIFLSDDAS 403
BLAST of Protocadherin alpha-11 vs. Ensembl Fly
Match: ft (gene:FBgn0001075 transcript:FBtr0077478) HSP 1 Score: 218.394 bits (555), Expect = 6.520e-57 Identity = 211/712 (29.63%), Postives = 330/712 (46.35%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNK----------GIKPFLKLRR--GIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAIL----RV----KKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI---LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLI-TNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSL--YDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR--ETLLP--FKLNPNSGELYSYDLVDRETQPSQYTFSITARD--SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYK-------IQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGEL-LTSTVLSVIH-KGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+ I++LD NDN P++ + SI I E+ + L L A D+D N + T +Y ++ NK G +L L +DRE + + + A DGG+P + G LQ+ + I+DVNDN PIF+ S Y S++ + T + + A+D D+ N+ +TY + + F +NP ++ RV + ++K F++ A DHG P + +T VT++L + N + P I P V + EN G V+ VKD+DSG++G+ + I+ + + E A + ++ N + DRE + L + D G PA T+A + I + DVND+ P FEK Y + E +A +TA D D G+NAQ+ Y I L + + L + I+ LDRE R + A D G + T + + ++D ND P F Q N++ ED + VA+ A D D G NG VT+++ E L P F L+ +G+L + +DRE SQY S+ ARD +PT ++AT +V + + D NDN+P F +P Y I+L V ++ V A DKD G N+ I++ LE LF ++ SG + L + +H K L + A D G R + Q +EI
Sbjct: 142 VRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLL-LDAATDADVGENGV-------TDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLN-ETALPGTPVVTVMASDNDLGDNSKITYYLAE-----TEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNE------LGHFRLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGL-----IVTTGPLDRE-----IRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQT---IVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKM-SQYEISVIARDQGAPT----PQSATATVWLNVADVNDNDPQF-YPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGEG-LFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRR--SQQDAIVEI 811 HSP 2 Score: 168.318 bits (425), Expect = 1.840e-41 Identity = 191/724 (26.38%), Postives = 332/724 (45.86%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPN-NISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEI----------------NSTLDLKIHATDLD----INANVT----------YRFSLNVPFIVQDCFD-LNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTT-VTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAI-QSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTT-VSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDF-GVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVL-----SVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNP----DSTPFN 2418
IQ+ D NDN P + ++ EN + + + ARD+D N +SY + + F + ++ L L +D E + + + + A D G PS + ++ + ++D+NDN PIF+ Y+ + N+ I N ++ I A D+D I++N T +R + + +DC D F+ + + LK+ + + L H + S T VT+ +K+ N P + A I+EN I V++ DND G +G + + E ++ D+ + S N L DRE+++ L I +D G+P +T +++ I I+D NDNSP F+ + Y ++ E + Q++A D+D+G N ++RY I L D N + + ++ + ++L+ E+ R+ V A D +G T ++I ++DINDN P F + Y +E+ N V A+D D +N V Y + F++N +SG++ +DRE Q S+YT ++ A D+ + L T T V + ++D NDN+P+F +Y + +P G+ V +A DKD G+N++++F L E + F I+ +GE+ T+T L SV H TL + PR +++ LTI + + + DST +N
Sbjct: 1910 IQVSDTNDNPPLFEDTVYSFDIPENAQR-GYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQTG-----MLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETA---IMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSI----VLGDQNHDFSISEDTGVVRVAKNLNYERLS---RYSL--TVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENT-VPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSGDIALLKPLDREQQ-SEYTLTLVAMDTGSPPL---TGTGIVRVEVQDINDNDPVFEL---QSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMH-RFHIDSETGEISTATTLDREETSVYHL---TLMAQDSSITEPRASSV-NLTISVSDVNDNIPKFDSTTYN 2602 HSP 3 Score: 167.548 bits (423), Expect = 3.391e-41 Identity = 181/674 (26.85%), Postives = 297/674 (44.07%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPN-NISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGG-TPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASE---YRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAF-YNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKD-SGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIH----KGEETLF---IKAIDCGSPRL 2352
I+ +++ D NDN P + S V EN + L P+A D DE N + + + F I SE + +DRE S +++TL+A D T + S+ L I + DVNDN P F+S+ Y ++ + + A DLD N ++++ Q FD+N ++ K LK + + + Y I A+D G SK +T+ L+ L+P + N+ + E+ G +I G+ GK +I I+ + N ++S+ + + D E+ ++ I D P+ + I++ + D NDN+P E+ Y+ + EE P IA + A D D G N + YR+Q D + ++ + +I LDRE+ + + FV V A D G P +G+ +V + L+D NDN P F + F N++ + GS V + D D G N + +YS F++ P SG + +DRE Q +Y + A D +R A ++I I+D NDN P F S Y L +LV + A D+D G NS I + L++ + +FSI+ +GE+ + + H + E ++ + A D G P L
Sbjct: 2476 IVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVL-TPRATDKDEGLNAKLRFNLLGEHMHRFHIDSETGE------ISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFV-FGARALDLDDGENAVVHYTIS--GRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELFPTFAYMA--NSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGG-----IMGDSLRVDPNSGLLSVGQDGL-DYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDF-----DGTFEITESGEIYTRMRLDREEIGD-YAFV----VEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRLFSLNVTENAEIGS-----FVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGNITVAGHLDREQQ-DEYILKVVASDG----AWR--AETPITITIQDQNDNAPEF---EHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQP--SPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPL 3104 HSP 4 Score: 159.458 bits (402), Expect = 1.013e-38 Identity = 197/731 (26.95%), Postives = 305/731 (41.72%), Query Frame = 1
Query: 370 KILEIQILDENDNVPQW-SQNSIVIE-VVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNK-----PIFES-SFYTQSIDCNLEINST-LDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDS----------GMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL-LPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD-------------SPTNLLYRK--------------------TATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNIL-------FSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
K++ + + D NDN P + S N+ ++ +K S + A+D+D N + Y+I + F + N GI F G + + +TL + D S+ S ++ I II P FE S + S+ N I ++ L + H +I VT + V FD++ IL L E EY + A+ G S+T V + + ++N PP L V + E+ IG I T D D+ G DGKF +LEP +IL N DRE K++ +L I D + T A +I + D NDN P FE Y + I E Q + + Q+ A D D G NAQL Y + D + N + + ++ + + R Y ++ Q A D+G+P S + TV ++D+NDN P+F Y+ E+ + +V A D D G NG + YSI + F ++ N G + + +DRE + S YT ++TARD + L YR ++TV V+I+I+D ND P+FI NE+ + V + ++V VKA+D D G N I ++++E + + FS+N T G+L L + L I A D G P + QL I I
Sbjct: 1585 KLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQELF--KLQRNTGIITFTP---GPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFL--DTPFVYNVSEDLQIGHTISTLRAHDPDTLGSVTFLLMDGHDGKF---LLEPSTGKLIL-----------------NDTLDRETKSKYELRIRVSDGVQ---YTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWA----NDVFSLNPQTGMLTLTA--RLDYEEVQHYILIVQ--AQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENV---PIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDSN-GTIRTRRNLDREHR-STYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANET----AIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRI 2268 HSP 5 Score: 151.754 bits (382), Expect = 2.372e-36 Identity = 145/568 (25.53%), Postives = 252/568 (44.37%), Query Frame = 1
Query: 712 IKIIDVNDNKPIF---ESSFYTQSIDCNLEINSTLDL-KIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTS---------------LYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR-ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLT 2355
I IID+NDN P+F S T S+ N + + L ++ D +N+ ++Y + N F + P +L +++ ++ E S + A D G P SK ++++ + + N + P + + + E + D D G +G+ + I+E + L DRE + L + C+D G+P+ ++ + I +ID NDN+PQF + ++I E + + +LTA D D G NA+L + + T +D L+KV N + R + + + +D+G P+ V + + D+NDN P F +A Y+++ E G+ + + VF D D G+NGDV YS+ + F L+ +G+L +DRE+Q + + A+D+ L + ++ S++IV+ D NDN P F +S+ ++ + P G+ + +A D D G+NSQ+ F + R F I+ +G L L TL I A DCG+P L+
Sbjct: 930 IAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNP----NQQFRIGPVTGVLYLQRPIRAEP-GSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTP--VFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVFPDGY--------LFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLL---EATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISE--GASEGTHITHVF-TQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLI-VVAKDAA--LKHPLSSNASITIVVLDENDNAPEF---TQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLS 1470 HSP 6 Score: 148.288 bits (373), Expect = 2.496e-35 Identity = 176/683 (25.77%), Postives = 308/683 (45.10%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKY--FFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLD--INANVTYRFSLNVPFIVQD-CFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTT---VTLHLKNQNLYPPSILLPGNNAVI--RIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEX-----XXXXXDVNDNSPQFEKEFYHYTIFEENQP-NFTIAQLTAHDLDDGLNAQLRY---RIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQA--FYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKT-ATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLT 2355
+ I +LDENDN P+++Q+S + V+E + + + +A D+D+ N+ + I ++ F I S I L L + +D E I+ + + + A D GTPS + ++ + ++D NDN PIF S+ + I + + + + + + A D D +N V+Y S P + Q F +N ++ + + E + +R ++ A D +P E+ +T VT+ +++ N P + + N A++ + ++ ++ KD DS +G I+ L N II+ F +EV R QL + D + S+E+ + + PQFE+ EN+P +I +TAH +A++ Y + S ++L +++ I++ + LDRE P + +V A G R+ T V + ++D ND+ P F YN+S ED + ++ AHDPD G VT+ ++ F L P++G+L D +DRET+ S+Y I D + Y + AT+ VS D NDN P+F ++ Y + G V + A D D G N+Q+ + + + N +FS+N +G L + L L ++A D G P L+
Sbjct: 1370 ITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRF-RASDADQGVNSQVVFSISAGNRRDTFHIDS------ITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPI-VTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDT-FRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAP-VFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQELFKL------QRNTGIITFTPGPQFKQEV--RYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHLA----SAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEV----EVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVS--EDL---QIGHTISTLRAHDPD--TLGSVTFLLMDGHDGKFLLEPSTGKLILNDTLDRETK-SKYELRIRVSD---GVQYTEAYATIQVS----DTNDNPPLF---EDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLS 2008 HSP 7 Score: 143.28 bits (360), Expect = 8.085e-34 Identity = 167/640 (26.09%), Postives = 284/640 (44.38%), Query Frame = 1
Query: 388 ILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKP--FLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSL-----NVPFIVQDCF--DLNPFN--AILRVKKSLKHECFASEYRFSIDA---------LDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENI--AIISLITNKIFDREVKTRIQLIIFCKDFG-KPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPY--QVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR-ETLLP----FKLNPNSGELYSYDLVDRETQPS-QYTFSITARDSPTNLLYRKTATVS-VSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQF 2208
I D ND+ P + S + E TK+++ + L A D D N ISY IE ++ F G+ P +L +R +DRE ++ +T+ D G PS++ + ++I +ID NDN P F +S +T SI N + T K+ A D DI N F+L + ++ F L PF+ A+++V ++ + R S+ D+G P + K V + + + N P L + + I E G I +D D G++G Y + N+ N+ A L + DRE + LI+ KD K +++A I+I+++D NDN+P+F + ++ E + + + A D D G+N+Q+ + I S + ++S + + P + + Y + A+D G P S + ++ ++D NDN P+F E K + A DPD G+NG V+Y+I + E LP F +N +G +++ +DRE+ + + T T R P+ R+ +T V++++ED NDN P+F+ N + + S + V V A D DS N + +
Sbjct: 1039 IADVNDHTPVFDHTSYETSLPETTKVNTRFFAL-AATDIDLGDNGRISYEIIEGNTERMF--------GVFPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPAD-TFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYH--VTISEGASEGTHITHVFTQDADEGLNGDV---------YYSLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSI----SAGNRRDTFHIDSITGSLYLHK------PLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKT---PIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSE---RQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTY 1641 HSP 8 Score: 142.124 bits (357), Expect = 2.085e-33 Identity = 186/760 (24.47%), Postives = 325/760 (42.76%), Query Frame = 1
Query: 127 IFENLPVGSVICKLSNV---IIPRPSDTTKFKLIKNRFFQIE-NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRG-IDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFT-IAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRET-LLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGI-NSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+ EN +GS + ++++ + + + F F+IE N+ V+G +DR+ E + V WR + I I D+NDN P++ + E + + ++ + PN++ Y ++ S F I K ++ + R + + +T+LA D G P + I I+D ++N P FE + Y + + + +++HA D +SL + F + F + + + + K ++ + Y + A D G P + +T V + + +N+ P + N+ + + EN+ +G ILT D+D+G +G SI +T ++ + D ++ L I +D G ++ A ++II+ DVNDN P F + YH I EN+P T + Q A D D NA + Y + S D + I +SN I + S D E+ R + Q+ A + S + + ++ +N+ P F Q ++ E + +V A D D G +G V Y +V + F+++ N+G +Y +DRETQ ++ ++ A++ ++ T V I I+D ND P FI + Y +S PVG+ VT VKAIDKD N+Q + + F I+ +GE+ T++ L L I AID G P T + IE+
Sbjct: 2921 VTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGNITVAGHLDREQQDEYI-LKVVASDGAWRA--------ETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDA-VRGQRIVRVHANDKQDLGTNEMDYSL-MTFNLSSIFSVGRHDGWITLVKPIQVPP-NTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSV--NSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGG-------IVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYI-PENKPVGTFVFQAHAADKDSPKNAIIHY--AFLPSGPDRHFFIMNQSNGTISSAVSFDYEE-----RRIYTLQIKAKNPDSSMES-YANLYVHVLGVNEFYPQFLQPVFHFDVSE---TSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKGFRIDTNTGLIYVARHLDRETQ-NRVVLTVMAKNY-GSIRGNDTDEAQVIISIQDGND-PPEFI---KHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIEL 3641 HSP 9 Score: 141.739 bits (356), Expect = 2.710e-33 Identity = 183/674 (27.15%), Postives = 303/674 (44.96%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWS---QNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIEN--QDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQ----------------------LIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKV---ESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSG-EPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV----RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNI----LFSINETSGELLT 2274
I+ I I+D NDN P ++ ++ I + EN + + L + RD D N+ ISY ++ F I + L L+R I E S +V L+A D G+P + L L + I DVND+ P+F+ + Y S+ ++N+ + ATD+D+ N + + + + F + P + L V+ L E Y ++ D G+P S V +H+ ++N P + I EN D V LT V D D G + + + + L + D + + N I +L + FDRE ++ L D G P ++ +I+ DVNDN+P+F + YH TI E I + D D+GLN + Y SL N+ + + Q+ + LDRE + + V+A D+ + S + +++I ++D NDN P F Q+ +S LE + ++ F A D D GVN V +SI R+T F ++ +G LY + +D E S YT +ITA D T L + TV ++++ D NDN P IFP+ + + Q+ +P+ + + V A D DSG+N ++ + + +++ + F IN +G + T
Sbjct: 927 IVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQ-EIYLSRVRDRDAGVNSRISYSLTNNPNQQFRIGP------VTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRF-FALAATDIDLGDNGRISYEI-IEGNTERMFGVFP-DGYLFVRAPLDRE-ERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFT--NSTFTFSIPENAPADTFVGKLTAV--DRDIGRNAELSFT-LSSQTQDFTI-----DTRNGFIKTL---RPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYY------SLAKGNEAGQFNLDSATGQLSLGRRLDRES-----QEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLE---TSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDT---FHIDSITGSLYLHKPLDYEDITS-YTLNITASDCGTPSL---STTVLYNVLVVDDNDNPP--IFPSTAIVR-QIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHT 1552 HSP 10 Score: 137.887 bits (346), Expect = 3.369e-32 Identity = 175/683 (25.62%), Postives = 298/683 (43.63%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTG-SLQLLIKIIDVNDNKPIF-ESSFYTQSIDCNLEINSTLDLKIHATDLD---INANVTYRFSLNVPFIVQ---DCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKD--FGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQ-QAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLL-PFKLNPNSGEL-YSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
L I+ILDENDN P + V EN + + L++ A D DE N I Y + + F SE + +++ + ++ E +S +++T+ A D + G + +L I I+D+NDN+P F +S + + ++ + N L ++A D D +N+ V Y F+ + D F +N + + + K L E SEY ++ A+D G P V + +++ N P L +A +R EN G +LT D D G++ K ++L + + SE I + T DRE + L + +D +P +S ++I + DVNDN P+F+ Y+ + E + A DLDDG NA + Y I Y + + +++ + + K + + A D GE S +++ ++ + P F A + + ED K KV+ A P G+ G + Y+I + +++PNSG L D +D E Y I A D T L T +++ + D NDN P+ + Y ++ L+ +VKA D+DSG N + + L+ + F I E SGE+ T L G+ ++A+D G P +T + + +
Sbjct: 2264 LLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQV-SATDVDEGANGRIRYSIVLGDQNHDFSISEDTG-----VVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRY-------FLKEGDSDLFRINASSGDIALLKPLDREQ-QSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVR--ENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHRFHI-----DSETGEISTATT---LDREETSVYHLTLMAQDSSITEPRA-SSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQHY-----FDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTV-ILRPPELFPTFAYMANSHFAMSEDVRPGKMITKVS---ATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELT-HLYEIWIEAADGDTPSLRSVTL---ITLNVTDANDNAPVM---EQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGT-FEITE-SGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHL 2903 HSP 11 Score: 126.716 bits (317), Expect = 9.495e-29 Identity = 140/548 (25.55%), Postives = 238/548 (43.43%), Query Frame = 1
Query: 898 FDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYD--IILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVES-----NC-QIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFY----NISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSY---DLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCG-SPRLTAIQQLTIEIGEFRNPDSTPFNETEE--SFLSDQATFIIVGIILGT 2484
F L+P ++ L E Y + + P+E + ++ + PSI I E+ G +L D D G +G + + N D L S + + + L T DRE + QL I +D G P ++++ I+DVNDN P F+ Y+ ++ E P + + A D D G N+++ Y + + N V S NC Q ++S +K C + V A D G P++ G T V++ L+D ND+ P+ F+ ++ +++ + N VA D D G+NG + IV L F+L + +L+ ++DRE + +Y ++ A D T +T T + I + D ND+EP+F +S Y LS L P GS V + A D+D+G+N+Q+ + + FS++ +G ++T+ L + L I A D G +P+ Q I + E N ++ F++ E+ + D IV ++ T
Sbjct: 103 FTLDPVTGEVKTNVVLDREGMRDHYDLVVLSSQPTYPIEVRIKVLDVNDNSPEFPEPSI-------AISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQK-------SCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDE--NAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLE-EAADLHIVRVNGVLDRE-EIGKYNLTVVAMDQGTPA---RTTTAHLIIDVNDVNDHEPVF---EKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDE--NDEAPQFSQREQNVTLGEDAPPQTIVALMTAT 624 HSP 12 Score: 126.716 bits (317), Expect = 9.657e-29 Identity = 153/595 (25.71%), Postives = 253/595 (42.52%), Query Frame = 1
Query: 619 GIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDL--KIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLD-DGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRF---VCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTI 2376
G+D EL + + + A DG TPS + + + D NDN P+ E Y + LE S L + A+D D N NV YR + F++ I + + E +Y F ++A+D G P +V LHL ++N PP + + EN +IG ++ D D G + + S E + + +S NI + + DRE + L + D A+ I+I I D NDN+P+FE FY ++ E Q + Q+ A D D G N+ + Y SL P+ + ++ + + R K+ R + V+ATD+G+P V+I ++D ++N P F+QA Y +D + + R V V D G N ++ YS++ L F + + G + LV P + + R + + + T V IV+ N + P F ++Y++ + PVGS + V A D D+G N +++ + FS++E +G ++ L E L I D G L+++ LTI
Sbjct: 2767 GLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEV---LEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDF----DGTFEITESGEIYTRMRLDREEI--GDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFT---RLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRI---EPQSGNITVAGHL-----DREQQDEYILKVVASDG---AWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISY------SLQQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQD--AVRGQRIVRVHANDKQDLGTN-EMDYSLMTFNLSSIFSVGRHDGWIT---LVKPIQVPPNTRYELVVRATDRGVPPQSDET-RVVIVVTGENMDTPRFSV---NSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTI 3322 HSP 13 Score: 119.783 bits (299), Expect = 1.361e-26 Identity = 154/599 (25.71%), Postives = 260/599 (43.41%), Query Frame = 1
Query: 622 IDRELISWH-NVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINAN-VTYRFSLNVPFIVQDCFDL----NPFNAI----LRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFY----HYTIFEENQPNFT-IAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQ--VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYN--ISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILE---EEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
+DRE + H ++ +L+ P +++ IK++DVNDN P F S + + L L ATD D+ N VT ++ + V V + F L NP L +L E S Y+ +I A D G P V + + + N PP + ++ + + E G ++T + DND G + K + E ++ + S + + + +F +D G P + +++ ++D ND+ P F+ +EN N T +A + D D GLN + RI L + ++ ++ I+ + LDRE+ + Y V+A D G P R+ + + I++ D+ND+ PVF+++ Y+ +S L GS VA A D D GVN V Y I+ L F ++P +G + + +DRE + + SI+ARD N K A + ++I D ND P F ++ + L P ++V L+ A D D G N + F L E + F+++ +G+L T L + + + A D G+P
Sbjct: 118 LDREGMRDHYDLVVLSSQPTYP-----IEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDA-ATDADVGENGVTDQYEI-VAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGS-YQLNISARDGGSPPRFGYLQVNVTILDVNDNPP--IFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNEL--GHFRLEEAADLHIVRVNGVLDREE-------IGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGS-----FVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREIRDT-VELSISARDGGPN---PKFAYTQLKVIILDENDEAPQF---SQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAP 685 HSP 14 Score: 109.768 bits (273), Expect = 1.246e-23 Identity = 163/597 (27.30%), Postives = 252/597 (42.21%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKS----ENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTS--AEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLD-DGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVI--ATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYN--ISFLEDFGSKKNSRKVAVFIAHDPDFGVNGD-VTYSIVRETLLPF-KLNPNSGELYSYDLVDRETQP-----------------SQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDN 2076
I + EN + P++S NS + V EN + S L + A D D PN + Y I ++ S ++ GI +++ +D +LI +++ + D G + L I + DVNDN P+F Y I N + T + HA D D NA + Y F + P + F +N N + S +E Y I A + +E S + +H+ N + P L P + + E +G + D DSG DG+ Y +++ + K N +I + + DRE + R+ L + K++G N + A++ I I D ND P+F K +Y TI E + + A D D N Q Y I + +L K I V++ +I LDRE+ Y ++ A D+G P ++GS TV IEL D+NDN P F N IS E G+ + IA DPD NG TY ++ + ++ NSG + S DRE P SQ+ +IT D N ++ ++VS+ D N
Sbjct: 3217 IVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTV-GATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIV----IQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVG-TFVFQAHAADKDSPKNAIIHYAFLPSGPD--RHFFIMNQSNGTISSAVSFDYE-ERRIYTLQIKAKNPDSSME-SYANLYVHVLGVNEFYPQFLQPVFH--FDVSETSAVGTRVGAVQATDKDSGEDGRV---------YYLLVGSSNDKGFRIDTNTGLIYVA--RHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSI-INGNLKQSFK-IDVQTG-EISTASRLDREE-------TSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGT-----SIMTLIASDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDNPSTTRSLHIAVSLFNGDLPSN 3774
BLAST of Protocadherin alpha-11 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0304899) HSP 1 Score: 195.667 bits (496), Expect = 6.537e-50 Identity = 201/730 (27.53%), Postives = 329/730 (45.07%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEK--------SNKGIKPFLKLRRGIDRELISWHNVTLLAVD---GGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLD---LKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQ--IIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL------LPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEK-RNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFII-----VGIILG 2481
L++ +LD ND+ P + + E + S + L +A D D N Y IE + ++ ++ S G+ + R +DRE +++ + A D + +T + + +K++D NDN P F YT + + + T D I ATD D N R+++ + Q F ++ + + + K L +E S YR I A D G P + T + +++ + N P + ++EN +G I+ D+D G + + SI E ++ + L ++ + T K DRE + R + KD G P + S+ + I + DVNDN P F ++Y + E+ P + +TA D D+ +++L Y I T+ + N + I QSLD Y RF+ V ATDSG RS + TV I + D N+ P+F+ A Y+ S ED V V A D D GVN +TYS+ E++ PF +NP +G + + +DRET S Y ++TA+D L + T V I + D NDN P F P Y+ + VG+ V V A D D G+N +I+++L + + F I+ TSG + T+ L L A+D GSP L++ ++ I + + N++ +F SD+ T + VG ++G
Sbjct: 450 LQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITL-RATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGV---ISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPED-QWGGTEDNTVAHIRATDADQGNNAAIRYAI-IGGNTQSQFSIDSMSGDVSLVKPLDYESVRS-YRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYT--SQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISE-RDDNFPLAVDPRTGW------VQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEI---TTGNTRGRFAITSQNGRGLITIAQSLD---YKQEKRFL--LTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFED---APVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETT-SGYLLTVTAKDGGNPSL---SDTTDVEIGVTDVNDNAPAFKSP---LYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLED--------VNDSPPTFASDKITLYVPENSPVGSVVG 1133 HSP 2 Score: 179.104 bits (453), Expect = 7.955e-45 Identity = 180/658 (27.36%), Postives = 301/658 (45.74%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENT--KLDSFYLELPKARDSDEHPNNISYYKI--EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSL-----NVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDT--SLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL--LPFKLNPNSGELYSYDLVDRETQPSQYTFSITA----RDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSG----ELLTSTVL 2286
+++++LD+NDN PQ+S+ + ++V E+ + + +A D+D+ N Y I T F I S + + L + +D E + + + + A DGG+PS++ + QLL+ +ID NDN P F +S + +S+ N+ + + +++ A D D AN +S+ N P V +P ++ K L E + F + A D G P + + ++V + +++ N P+ A + E+Q G + T D D + + + I + N IA + D + + R L + D G + +A + I I D N+ +P FE Y ++FE+ T+ ++A D D G+NAQ+ Y + ++ L P+ I+ LDRE +G+ V A D G P S +T V I + D+NDN P F+ Y S LED + +VA A DPD G+NG + Y + + F ++P SG + + +DRE S F +TA + SP ++TV V I +ED ND+ P F + Y + S PVGS+V + A D D G+N+ + + + + FS+ G +LLT T L
Sbjct: 567 VQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGD------VSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNI-IRVQAYDSDEGANAEITYSISERDDNFPLAV------DPRTGWVQTIKPLDRE-EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEA--NVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIA-------QSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETT-SGYLLT----VTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVA---ASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRE---SVAVFHLTAIAVDKGSPP-----LSSTVEVQIRLEDVNDSPPTFASDKITLYVPENS---PVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTEL 1180 HSP 3 Score: 165.236 bits (417), Expect = 1.563e-40 Identity = 163/611 (26.68%), Postives = 277/611 (45.34%), Query Frame = 1
Query: 622 IDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNV----PFIVQD----CFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKT-TVTLHLK---NQNLYPPSILLPGNNAVIRIIENQDIGV---VILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQII-AIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR-ETLLPFKLNPNSGE-LYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNIL-----FSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIG 2385
+DREL+ H ++A D P ++G+ L + ++D ND+ P FE+ + SI + ST+ + + ATD DI N + + + QD F ++ + ++ + SL E + Y + A D + +T T ++ +K + + YP +++ E+Q G + D D G + +I+ N +++ + +SL+ K D E +L+I +D G P+ + + ++ + +ID NDN+P+F + ++ E + I ++ A+D D+G NA++ Y I S D N + V+ + I+ LDRE+ RF +QV+A D G P +S S++V I + D+NDN P F +Y + ED + V A DPD + + Y I T F + +G L + Q ++ ++ A DS ++ T +V I I D N+ PIF + Y + PVG+ V +V A D D G+N+QI + L EE N L FSIN +G ++T+ L L + A D G+P L+ +EIG
Sbjct: 422 LDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTV-ITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRET-SDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYP---QFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIG-GNTQSQFSIDSMSGD----VSLV--KPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSI----SERDDNFPLAVDPRTGWVQTIKPLDREEQ---GRFA--FQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGED---QPPGTPVTTVTATDPD--EDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGG-----RSDTATVHINITDANNFAPIF---ENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLS--DTTDVEIG 996 HSP 4 Score: 159.073 bits (401), Expect = 1.205e-38 Identity = 184/724 (25.41%), Postives = 310/724 (42.82%), Query Frame = 1
Query: 361 NNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNA--ILRVKKSLKHECFASEYRF--SIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTK--SENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR---ETLLPFKLNPNS--GELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIF-----IFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI---GEFRNPDSTPFNE-TEESFLSDQATFIIVGI 2472
+N L + ++D NDN P++ + V+EN + + + +A DSDE N Y I F ++ + ++ L DRE ++A DGG P K+ S ++I + DVNDN P F +Y ++ + + + + ATD D ++ + Y + + F + N ++ + +SL + E RF ++ A D G TV +++ + N + P + + E+ +G +L D+D G++ + S+ N + I + S N +++TN DRE + L + KD G P+ + + ++ I + DVNDN+P F+ Y +I E+ ++ Q+ A D D GLN +++Y + D + D + +I S I + LDRE V IA D G P S + V I L D+ND+ P F + E+ V AHDPD GVN V YSI+ P S +L + +D E+ ++ + A P R A + I++ D NDN P+ IF N ++ P G + + A D D ++ ++ + + L +N +SG L+ S L+ T+ + D G AI QL++ + N + NE TEE+FLS F + G+
Sbjct: 670 SNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRV-QAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPL----DREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPV-TTVTATDPDEDSRLHYEITTGN---TRGRFAITSQNGRGLITIAQSLD---YKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAP--IFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSL----NEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLS-DRDIEDGSFVIDPTSG-TIRTNKGLDRESVA-----VFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPEN---SPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPP----LRNDA--HIEILVTDVNDNAPVLRDFQVIFNNFRDH-------FPSGE-IGRIPAFDAD--VSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSD-GINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTEEAFLSPLLNFFLDGL 1346 HSP 5 Score: 113.235 bits (282), Expect = 1.238e-24 Identity = 117/467 (25.05%), Postives = 208/467 (44.54%), Query Frame = 1
Query: 1030 VTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDT---SLYDPNKL--IKVESNCQIIAIQ-SLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV-RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD--SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPD 2403
V L+NQ+ Y L V ++E Q G + T +D + S+L+ ++ + ++T + T+ DRE+ + D P + + + + ++D ND+SP FE E + +I E T+ L A D D G NA++ Y I+ T L ++ +++S +I+ + SLDRE + + + +A+ E +R+ + +V ++++D NDN P F + Y + ED VA A D D G N + Y+I+ T F ++ SG++ +D E+ S Y I A+D SP+ ++ T + + + D NDN P F S ++ + VPVG + V+A D D G N++I + + E N +++ +G + T L +G + A D G P +A + I + + + D
Sbjct: 348 VRRELRNQSPYFEQALY-----VASVLEEQPAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQSLFKVDSRTGV-------VTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRET-SDSYHLLVTAADLASAQSE-RRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRS-YRLVIRAQDGGSPS-----RSNTTQLLVNVIDANDNAPRFY---TSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDND 791
BLAST of Protocadherin alpha-11 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0300578) HSP 1 Score: 195.667 bits (496), Expect = 6.537e-50 Identity = 201/730 (27.53%), Postives = 329/730 (45.07%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEK--------SNKGIKPFLKLRRGIDRELISWHNVTLLAVD---GGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLD---LKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQ--IIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL------LPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEK-RNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFII-----VGIILG 2481
L++ +LD ND+ P + + E + S + L +A D D N Y IE + ++ ++ S G+ + R +DRE +++ + A D + +T + + +K++D NDN P F YT + + + T D I ATD D N R+++ + Q F ++ + + + K L +E S YR I A D G P + T + +++ + N P + ++EN +G I+ D+D G + + SI E ++ + L ++ + T K DRE + R + KD G P + S+ + I + DVNDN P F ++Y + E+ P + +TA D D+ +++L Y I T+ + N + I QSLD Y RF+ V ATDSG RS + TV I + D N+ P+F+ A Y+ S ED V V A D D GVN +TYS+ E++ PF +NP +G + + +DRET S Y ++TA+D L + T V I + D NDN P F P Y+ + VG+ V V A D D G+N +I+++L + + F I+ TSG + T+ L L A+D GSP L++ ++ I + + N++ +F SD+ T + VG ++G
Sbjct: 450 LQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITL-RATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGV---ISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPED-QWGGTEDNTVAHIRATDADQGNNAAIRYAI-IGGNTQSQFSIDSMSGDVSLVKPLDYESVRS-YRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYT--SQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISE-RDDNFPLAVDPRTGW------VQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEI---TTGNTRGRFAITSQNGRGLITIAQSLD---YKQEKRFL--LTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFED---APVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETT-SGYLLTVTAKDGGNPSL---SDTTDVEIGVTDVNDNAPAFKSP---LYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLED--------VNDSPPTFASDKITLYVPENSPVGSVVG 1133 HSP 2 Score: 179.104 bits (453), Expect = 7.955e-45 Identity = 180/658 (27.36%), Postives = 301/658 (45.74%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENT--KLDSFYLELPKARDSDEHPNNISYYKI--EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSL-----NVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDT--SLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL--LPFKLNPNSGELYSYDLVDRETQPSQYTFSITA----RDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSG----ELLTSTVL 2286
+++++LD+NDN PQ+S+ + ++V E+ + + +A D+D+ N Y I T F I S + + L + +D E + + + + A DGG+PS++ + QLL+ +ID NDN P F +S + +S+ N+ + + +++ A D D AN +S+ N P V +P ++ K L E + F + A D G P + + ++V + +++ N P+ A + E+Q G + T D D + + + I + N IA + D + + R L + D G + +A + I I D N+ +P FE Y ++FE+ T+ ++A D D G+NAQ+ Y + ++ L P+ I+ LDRE +G+ V A D G P S +T V I + D+NDN P F+ Y S LED + +VA A DPD G+NG + Y + + F ++P SG + + +DRE S F +TA + SP ++TV V I +ED ND+ P F + Y + S PVGS+V + A D D G+N+ + + + + FS+ G +LLT T L
Sbjct: 567 VQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGD------VSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNI-IRVQAYDSDEGANAEITYSISERDDNFPLAV------DPRTGWVQTIKPLDRE-EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEA--NVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIA-------QSLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETT-SGYLLT----VTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVA---ASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRE---SVAVFHLTAIAVDKGSPP-----LSSTVEVQIRLEDVNDSPPTFASDKITLYVPENS---PVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTEL 1180 HSP 3 Score: 165.236 bits (417), Expect = 1.563e-40 Identity = 163/611 (26.68%), Postives = 277/611 (45.34%), Query Frame = 1
Query: 622 IDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNV----PFIVQD----CFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKT-TVTLHLK---NQNLYPPSILLPGNNAVIRIIENQDIGV---VILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQII-AIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR-ETLLPFKLNPNSGE-LYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNIL-----FSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIG 2385
+DREL+ H ++A D P ++G+ L + ++D ND+ P FE+ + SI + ST+ + + ATD DI N + + + QD F ++ + ++ + SL E + Y + A D + +T T ++ +K + + YP +++ E+Q G + D D G + +I+ N +++ + +SL+ K D E +L+I +D G P+ + + ++ + +ID NDN+P+F + ++ E + I ++ A+D D+G NA++ Y I S D N + V+ + I+ LDRE+ RF +QV+A D G P +S S++V I + D+NDN P F +Y + ED + V A DPD + + Y I T F + +G L + Q ++ ++ A DS ++ T +V I I D N+ PIF + Y + PVG+ V +V A D D G+N+QI + L EE N L FSIN +G ++T+ L L + A D G+P L+ +EIG
Sbjct: 422 LDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTV-ITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRET-SDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYP---QFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIG-GNTQSQFSIDSMSGD----VSLV--KPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSI----SERDDNFPLAVDPRTGWVQTIKPLDREEQ---GRFA--FQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGED---QPPGTPVTTVTATDPD--EDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGG-----RSDTATVHINITDANNFAPIF---ENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLS--DTTDVEIG 996 HSP 4 Score: 159.073 bits (401), Expect = 1.205e-38 Identity = 184/724 (25.41%), Postives = 310/724 (42.82%), Query Frame = 1
Query: 361 NNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNA--ILRVKKSLKHECFASEYRF--SIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTK--SENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR---ETLLPFKLNPNS--GELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIF-----IFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI---GEFRNPDSTPFNE-TEESFLSDQATFIIVGI 2472
+N L + ++D NDN P++ + V+EN + + + +A DSDE N Y I F ++ + ++ L DRE ++A DGG P K+ S ++I + DVNDN P F +Y ++ + + + + ATD D ++ + Y + + F + N ++ + +SL + E RF ++ A D G TV +++ + N + P + + E+ +G +L D+D G++ + S+ N + I + S N +++TN DRE + L + KD G P+ + + ++ I + DVNDN+P F+ Y +I E+ ++ Q+ A D D GLN +++Y + D + D + +I S I + LDRE V IA D G P S + V I L D+ND+ P F + E+ V AHDPD GVN V YSI+ P S +L + +D E+ ++ + A P R A + I++ D NDN P+ IF N ++ P G + + A D D ++ ++ + + L +N +SG L+ S L+ T+ + D G AI QL++ + N + NE TEE+FLS F + G+
Sbjct: 670 SNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRV-QAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPL----DREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPV-TTVTATDPDEDSRLHYEITTGN---TRGRFAITSQNGRGLITIAQSLD---YKQEKRFLLTVAATDSGG--RSDTATVHINITDANNFAP--IFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSL----NEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLS-DRDIEDGSFVIDPTSG-TIRTNKGLDRESVA-----VFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPEN---SPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPP----LRNDA--HIEILVTDVNDNAPVLRDFQVIFNNFRDH-------FPSGE-IGRIPAFDAD--VSDKLHYRILSGNNANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSD-GINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTEEAFLSPLLNFFLDGL 1346 HSP 5 Score: 113.235 bits (282), Expect = 1.238e-24 Identity = 117/467 (25.05%), Postives = 208/467 (44.54%), Query Frame = 1
Query: 1030 VTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDT---SLYDPNKL--IKVESNCQIIAIQ-SLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV-RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD--SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPD 2403
V L+NQ+ Y L V ++E Q G + T +D + S+L+ ++ + ++T + T+ DRE+ + D P + + + + ++D ND+SP FE E + +I E T+ L A D D G NA++ Y I+ T L ++ +++S +I+ + SLDRE + + + +A+ E +R+ + +V ++++D NDN P F + Y + ED VA A D D G N + Y+I+ T F ++ SG++ +D E+ S Y I A+D SP+ ++ T + + + D NDN P F S ++ + VPVG + V+A D D G N++I + + E N +++ +G + T L +G + A D G P +A + I + + + D
Sbjct: 348 VRRELRNQSPYFEQALY-----VASVLEEQPAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQSLFKVDSRTGV-------VTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRET-SDSYHLLVTAADLASAQSE-RRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRS-YRLVIRAQDGGSPS-----RSNTTQLLVNVIDANDNAPRFY---TSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDND 791
BLAST of Protocadherin alpha-11 vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 238.81 bits (608), Expect = 3.224e-64 Identity = 201/680 (29.56%), Postives = 325/680 (47.79%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIE--PTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPF-IVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPG------NNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNC-QIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
I++ D NDN PQ+ + + V ENT + + + +P A D D N ++ Y + P + F ++G K P L + +DREL +++T+ AVDGG P + S L + I D NDN P FE S Y + N I ++ L++ A D D+ N ++L+ V ++ + I+ VK L E + +F + A D G + SKT V++ + +QN P++ + G ++ V I E+ +G + V D D G + C + + + + + +N L T D E ++ I D G PA +++ + + + D NDNSP F + EENQP + ++ A D D G NA+L Y I D+S L +++ N ++ A LDRE + + + F +V A D G P G+ TV I+++D NDN P F + Y+ S LE+ V + D D G N V S V + F + +G + S DRE + S YTF + A D +++ V V+I + D NDN P+ P+ S++ I+LS + S+V +V+A D DSG N+++ + + + LF I+ ++GE+ + L+ H G L IK D G P AI + I + E
Sbjct: 119 IEVQDINDNTPQFPSPVLTLSVPENTHMGALF-SIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSV-LQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSGIIYVKGPLDREEI-NNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQL-RPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSST---RGLFEIDPNSGEVRARSPLDRE-HKDRYEF----RVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLS---PVGMVTVQDMDEGENAQVQLS-VEPDVGKFVIQNGTGTILSSISFDREKE-SSYTFRLKAVDGGDP---PRSSYVGVTINVLDENDNAPVVTKPSNSSF-IRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRHAIALVHIYVNE 777 HSP 2 Score: 144.436 bits (363), Expect = 2.144e-34 Identity = 154/564 (27.30%), Postives = 253/564 (44.86%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYY----KIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFE--------SSFYTQSIDCNLEINSTLDL-KIHATDLDINANVTYRFSLNVPFIVQDCFDL---NPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGEL-YSYDLVDRETQPSQYTFSITARDSPT 2010
+L + I D NDN P++ ++S EV EN+ + L++ KA DSD PN Y I+P K I + GI + ++ +DRE I+ ++A D G K+ + I + D NDN P E S +I ++ + + + L ++ D NA VT + +VPF ++ D N L+ L +E +YR I A+D G P S ++ + + + N P I P V ENQ G ++ V D DSG + + SI+ + + ++ E A L DRE K R + + D G P+ +A + I ++D NDN P+F Y +++ E P + +T D+D+G NAQ++ ++ D K + I++ S DREK + + F ++ A D G+P RS V+I ++D NDN PV + N SF+ V V A D D G N ++ YSI F ++P++GE+ + +L + + + ++ R P+
Sbjct: 228 LLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQV-KANDSDLGPNGEIEYTLHQAIDPVPKLLRID---RSSGI---IYVKGPLDREEINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTTTPLDYERV-RDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSP-IFSPTLFEVEFAEENQP-GEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPL------DREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVEPDV-----GKFVIQNGTGTILSSISFDREKE-SSYTF----RLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKP-SNSSFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPS 764 HSP 3 Score: 91.2781 bits (225), Expect = 4.727e-18 Identity = 103/403 (25.56%), Postives = 170/403 (42.18%), Query Frame = 1
Query: 1276 TNKIFDREVKTRIQLIIFCKDFGKPAF------------NTSA---EXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNC----QIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP----FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPI-----FIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGE------LLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
T IF E+ + + C++ GKP F N S E I + D+NDN+PQF ++ E + A D D N Y + L E Q+I + SLDRE + + A D G P R S + + + D NDN P F+++ Y E+ V A+D D G NG++ Y++ + + P +++ +SG +Y +DRE + + F + ARD + K++ VSI + D NDN P S+ +S +PVG+ V LV+ DKD G N+ + ++ + L +++S + L T+T L + + I A+D G+P L++ L +++
Sbjct: 70 TGDIFTTEIPIDRETLKDCRNKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRE-----LKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAEN---SPIGHSVLQVKANDSDLGPNGEIEYTL-HQAIDPVPKLLRIDRSSGIIYVKGPLDRE-EINNLKFYVVARDKGPS---PKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQV 459 HSP 4 Score: 62.003 bits (149), Expect = 4.882e-9 Identity = 80/304 (26.32%), Postives = 121/304 (39.80%), Query Frame = 1
Query: 1435 YTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-----------LDREKYPN----GFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVF---IAHDPDFGVNGDVTYSIVRE----TLLPFKLNPNSGE----LYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNI--LFSINETSG 2262
Y + EE P+ I L A D L D L K+E + + +DRE + G ++V TD + Q IE+ DINDN P F +S E N+ A+F +A D D NG Y++ L ++ + GE L +DRE + S Y +I A D Y ++ + +VI D NDN P F +S+Y+ +++ P+G V VKA D D G N +I++ L + + L I+ +SG
Sbjct: 27 YRVHEEQPPSTLIGSLAA-----------------DQGLPDTGHLYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLKDCRNKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPE------NTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDS-YDLTIKAVDGGNPPRY---SSALLRVVIADANDNAPKF---EKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSG 300
BLAST of Protocadherin alpha-11 vs. Ensembl Zebrafish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 238.039 bits (606), Expect = 1.400e-63 Identity = 201/680 (29.56%), Postives = 325/680 (47.79%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIE--PTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPF-IVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPG------NNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNC-QIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
I++ D NDN PQ+ + + V ENT + + + +P A D D N ++ Y + P + F ++G K P L + +DREL +++T+ AVDGG P + S L + I D NDN P FE S Y + N I ++ L++ A D D+ N ++L+ V ++ + I+ VK L E + +F + A D G + SKT V++ + +QN P++ + G ++ V I E+ +G + V D D G + C + + + + + +N L T D E ++ I D G PA +++ + + + D NDNSP F + EENQP + ++ A D D G NA+L Y I D+S L +++ N ++ A LDRE + + + F +V A D G P G+ TV I+++D NDN P F + Y+ S LE+ V + D D G N V S V + F + +G + S DRE + S YTF + A D +++ V V+I + D NDN P+ P+ S++ I+LS + S+V +V+A D DSG N+++ + + + LF I+ ++GE+ + L+ H G L IK D G P AI + I + E
Sbjct: 119 IEVQDINDNTPQFPSPVLTLSVPENTHMGALF-SIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSV-LQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSGIIYVKGPLDREEI-NNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQL-RPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLFEVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSST---RGLFEIDPNSGEVRARSPLDRE-HKDRYEF----RVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLS---PVGMVTVQDMDEGENAQVQLS-VEPDVGKFVIQNGTGTILSSISFDREKE-SSYTFRLKAVDGGDP---PRSSYVGVTINVLDENDNAPVVTKPSNSSF-IRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPSRHAIALVHIYVNE 777 HSP 2 Score: 144.436 bits (363), Expect = 2.874e-34 Identity = 149/568 (26.23%), Postives = 253/568 (44.54%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYY----KIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFE--------SSFYTQSIDCNLEINSTLDL-KIHATDLDINANVTYRFSLNVPFIVQDCFDL---NPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQN----LYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGEL-YSYDLVDRETQPSQYTFSITARDSPT 2010
+L + I D NDN P++ ++S EV EN+ + L++ KA DSD PN Y I+P K I + GI + ++ +DRE I+ ++A D G K+ + I + D NDN P E S +I ++ + + + L ++ D NA VT + +VPF ++ D N L+ L +E +YR I A+D G P S ++ + + + N ++ P++ + E G ++ V D DSG + + SI+ + + ++ E A L DRE K R + + D G P+ +A + I ++D NDN P+F Y +++ E P + +T D+D+G NAQ++ ++ D K + I++ S DREK + + F ++ A D G+P RS V+I ++D NDN PV + N SF+ V V A D D G N ++ YSI F ++P++GE+ + +L + + + ++ R P+
Sbjct: 228 LLRVVIADANDNAPKFEKSSYEAEVAENSPIGHSVLQV-KANDSDLGPNGEIEYTLHQAIDPVPKLLRID---RSSGI---IYVKGPLDREEINNLKFYVVARDKGPSPKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTTTPLDYERV-RDYRVEIVAVDSGNPALSSTNSLKVQVTDTNDNSPIFSPTLF------EVEFAEENQPGEKVVEVVASDADSGTNAELVYSIIADSSTRGLFEIDPNSGEVRARSPL------DREHKDRYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVQDMDEGENAQVQLSVEPDV-----GKFVIQNGTGTILSSISFDREKE-SSYTF----RLKAVDGGDPPRSSYVGVTINVLDENDNAPVVTKP-SNSSFIRLSPMAAPDSVVEVVEAEDIDSGSNAELVYSIAGGNPHDLFYISPSNGEITLTKELTRKHSGLHRLVIKVSDRGKPS 764 HSP 3 Score: 90.8929 bits (224), Expect = 7.485e-18 Identity = 103/403 (25.56%), Postives = 170/403 (42.18%), Query Frame = 1
Query: 1276 TNKIFDREVKTRIQLIIFCKDFGKPAF------------NTSA---EXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNC----QIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP----FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPI-----FIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGE------LLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
T IF E+ + + C++ GKP F N S E I + D+NDN+PQF ++ E + A D D N Y + L E Q+I + SLDRE + + A D G P R S + + + D NDN P F+++ Y E+ V A+D D G NG++ Y++ + + P +++ +SG +Y +DRE + + F + ARD + K++ VSI + D NDN P S+ +S +PVG+ V LV+ DKD G N+ + ++ + L +++S + L T+T L + + I A+D G+P L++ L +++
Sbjct: 70 TGDIFTTEIPIDRETLKDCRNKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPENTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRE-----LKDSYDLTIKAVDGGNPPRYSSALLRVVIADANDNAPKFEKSSYEAEVAEN---SPIGHSVLQVKANDSDLGPNGEIEYTL-HQAIDPVPKLLRIDRSSGIIYVKGPLDRE-EINNLKFYVVARDKGPS---PKSSKTYVSIDVTDQNDNAPAVEIRGIGLVTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSSVDNKRKYFLQTTTPLDYERVRDYRVEIVAVDSGNPALSSTNSLKVQV 459 HSP 4 Score: 61.2326 bits (147), Expect = 7.806e-9 Identity = 80/304 (26.32%), Postives = 121/304 (39.80%), Query Frame = 1
Query: 1435 YTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-----------LDREKYPN----GFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVF---IAHDPDFGVNGDVTYSIVRE----TLLPFKLNPNSGE----LYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNI--LFSINETSG 2262
Y + EE P+ I L A D L D L K+E + + +DRE + G ++V TD + Q IE+ DINDN P F +S E N+ A+F +A D D NG Y++ L ++ + GE L +DRE + S Y +I A D Y ++ + +VI D NDN P F +S+Y+ +++ P+G V VKA D D G N +I++ L + + L I+ +SG
Sbjct: 27 YRVHEEQPPSTLIGSLAA-----------------DQGLPDTGHLYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLKDCRNKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVPE------NTHMGALFSIPLATDKDTERNGVADYTLTAGPEAVALFGLQVAEDRGEKLPQLIVLGSLDRELKDS-YDLTIKAVDGGNPPRY---SSALLRVVIADANDNAPKF---EKSSYEAEVAENSPIGHSVLQVKANDSDLGPNGEIEYTLHQAIDPVPKLLRIDRSSG 300
BLAST of Protocadherin alpha-11 vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 226.483 bits (576), Expect = 4.140e-60 Identity = 197/670 (29.40%), Postives = 321/670 (47.91%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI----EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFI-VQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPG------NNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAI---DKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
I+ILDENDN PQ+S + + + ENT + + + +P A D D N I+ Y + E T+ + ++ S++ + P L + +DREL +++ + VDGG+P + S L I I D NDN P FE S Y + N + ++ L++ A D D+ N +SL+ P V ++ I+ VK S+ E S +F + A D+G + SK VT+ +K+QN PSI + G + V I E+ +G + V D D G + C + + + + ++T ++ L T + D E ++ I D G PA +++ + + + D+NDN+P F Y FEENQP + + A D D G NA+L Y I + P L ++ N + + S LDRE+ + ++F+ V A D G P G+ TV ++++D NDN P F Y+ S E+ V + +D D G N V S+ + F + + + S DRE + S Y+F + A D +++ V ++I + D NDN P P S+YK +L P S T V+++ D D G+NS++ F + + LF I+ + GE+ + + H G L +K D G+P
Sbjct: 142 IEILDENDNTPQFSSPVLTLSIPENTHVGALF-AIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKL-PQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSV-LQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEI-SILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQ-LRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSV---PEGLFEINPNTGEVRVMSQLDREQL-DHYQFL----VAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLS---PVGMVTVNDHDEGENARVQLSVEPDN-GKFMIQNGTYTILSTISFDREKE-STYSFRLKAVDGGDP---PRSSYVGITINVLDENDNAPYVTKPANSSYK----FLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRIS-SEGEITLAKEFTPKHIGLHRLVVKVKDKGTP 785 HSP 2 Score: 137.887 bits (346), Expect = 2.682e-32 Identity = 140/518 (27.03%), Postives = 237/518 (45.75%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKP--------IFESSFYTQSIDCNLEINSTLDL-KIHATDLDINANVTYRFSLNVPFIVQDCFDLN---PFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIP-VFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV 1884
+L I I D NDNVP++ ++ E+ EN+ + L++ KA DSD PN ++Y +P+S + S N GI + ++ +DRE IS + A D G SK+ + I + D NDN P + +I ++ + + + L ++ D NA VT + +VPF ++ + L+ L +E EYR I A+D G P S ++ + + + N P + P V ENQ G +L V D DSG + + SI + + +N E + ++S + DRE Q ++ D G P+ +A + + ++D NDN P+F Y +++ E P + +T +D D+G NA+++ ++ D K + I++ S DREK +++ A D G+P RS ++I ++D NDN P V + A + FL+ S + V A D D G+N ++ ++IV
Sbjct: 251 LLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQV-KANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGI---IFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERI-KEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAP-VFSPTLYEVEFFEENQP-GDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGE-VRVMSQL-----DREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNG-----KFMIQNGTYTILSTISFDREK-----ESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPET--HVESVEAEDIDIGLNSELDFNIV 743 HSP 3 Score: 113.62 bits (283), Expect = 7.898e-25 Identity = 120/453 (26.49%), Postives = 197/453 (43.49%), Query Frame = 1
Query: 1099 IRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPN----KLIKVESNCQIIAIQ-SLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIP----------VFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGE---------LYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQF-ILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+ I EN +G + V D DSG +G + ++ + ++ + + + LI DRE++ L I D G P +SA + I I D NDN P+FE+ Y + E + ++ Q+ A+D D G N ++ Y SL+ P+ +L+ ++ N II ++ S+DRE+ + + V A D+G +S V+I + D NDN P + NIS G+ VA+ D D G N VT + + +PF+L S L + L+D E + +Y I A DS L ++T S+ + + D NDN P+F + + Y+++ G V V A D DSG N+++ + I LF IN +GE+ + L + A D G P L + +++
Sbjct: 161 LSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTY------SLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEIS-----ILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGT-----AVALVEVSDRDEGENAVVTCVVAGD--VPFQLRSASETGNDRKRKYFLQTTTLLDYE-RIKEYRIEIVAVDSGNPAL---SSTNSLKVQVTDMNDNAPVF---SPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKV 588
BLAST of Protocadherin alpha-11 vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 226.098 bits (575), Expect = 4.760e-60 Identity = 197/670 (29.40%), Postives = 321/670 (47.91%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI----EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFI-VQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPG------NNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAI---DKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
I+ILDENDN PQ+S + + + ENT + + + +P A D D N I+ Y + E T+ + ++ S++ + P L + +DREL +++ + VDGG+P + S L I I D NDN P FE S Y + N + ++ L++ A D D+ N +SL+ P V ++ I+ VK S+ E S +F + A D+G + SK VT+ +K+QN PSI + G + V I E+ +G + V D D G + C + + + + ++T ++ L T + D E ++ I D G PA +++ + + + D+NDN+P F Y FEENQP + + A D D G NA+L Y I + P L ++ N + + S LDRE+ + ++F+ V A D G P G+ TV ++++D NDN P F Y+ S E+ V + +D D G N V S+ + F + + + S DRE + S Y+F + A D +++ V ++I + D NDN P P S+YK +L P S T V+++ D D G+NS++ F + + LF I+ + GE+ + + H G L +K D G+P
Sbjct: 127 IEILDENDNTPQFSSPVLTLSIPENTHVGALFA-IPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKL-PQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSV-LQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEI-SILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQ-LRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSV---PEGLFEINPNTGEVRVMSQLDREQL-DHYQFL----VAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLS---PVGMVTVNDHDEGENARVQLSVEPDNGK-FMIQNGTYTILSTISFDREKE-STYSFRLKAVDGGDP---PRSSYVGITINVLDENDNAPYVTKPANSSYK----FLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRIS-SEGEITLAKEFTPKHIGLHRLVVKVKDKGTP 770 HSP 2 Score: 137.502 bits (345), Expect = 3.002e-32 Identity = 140/518 (27.03%), Postives = 237/518 (45.75%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKP--------IFESSFYTQSIDCNLEINSTLDL-KIHATDLDINANVTYRFSLNVPFIVQDCFDLN---PFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIP-VFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV 1884
+L I I D NDNVP++ ++ E+ EN+ + L++ KA DSD PN ++Y +P+S + S N GI + ++ +DRE IS + A D G SK+ + I + D NDN P + +I ++ + + + L ++ D NA VT + +VPF ++ + L+ L +E EYR I A+D G P S ++ + + + N P + P V ENQ G +L V D DSG + + SI + + +N E + ++S + DRE Q ++ D G P+ +A + + ++D NDN P+F Y +++ E P + +T +D D+G NA+++ ++ D K + I++ S DREK +++ A D G+P RS ++I ++D NDN P V + A + FL+ S + V A D D G+N ++ ++IV
Sbjct: 236 LLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQV-KANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGI---IFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERI-KEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAP-VFSPTLYEVEFFEENQP-GDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGE-VRVMSQL-----DREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNG-----KFMIQNGTYTILSTISFDREK-----ESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPET--HVESVEAEDIDIGLNSELDFNIV 728 HSP 3 Score: 113.235 bits (282), Expect = 9.986e-25 Identity = 118/450 (26.22%), Postives = 195/450 (43.33%), Query Frame = 1
Query: 1096 VIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQ-SLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIP----------VFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGE---------LYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQF-ILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+ I EN +G + V D DSG +G + ++ + ++ + + + LI DRE++ L I D G P +SA + I I D NDN P+FE+ Y + E + ++ Q+ A+D D G N ++ Y + +S +L+ ++ N II ++ S+DRE+ + + V A D+G +S V+I + D NDN P + NIS G+ VA+ D D G N VT + + +PF+L S L + L+D E + +Y I A DS L ++T S+ + + D NDN P+F + + Y+++ G V V A D DSG N+++ + I LF IN +GE+ + L + A D G P L + +++
Sbjct: 145 TLSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPV--MRLLSIDRNTGIIFVKGSVDREEI-----SILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGT-----AVALVEVSDRDEGENAVVTCVVAGD--VPFQLRSASETGNDRKRKYFLQTTTLLDYE-RIKEYRIEIVAVDSGNPAL---SSTNSLKVQVTDMNDNAPVF---SPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKV 573
BLAST of Protocadherin alpha-11 vs. Ensembl Zebrafish
Match: CT030123.1 (protocadherin 1b [Source:NCBI gene;Acc:572016]) HSP 1 Score: 225.713 bits (574), Expect = 5.103e-60 Identity = 197/670 (29.40%), Postives = 321/670 (47.91%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI----EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFI-VQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPG------NNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAI---DKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
I+ILDENDN PQ+S + + + ENT + + + +P A D D N I+ Y + E T+ + ++ S++ + P L + +DREL +++ + VDGG+P + S L I I D NDN P FE S Y + N + ++ L++ A D D+ N +SL+ P V ++ I+ VK S+ E S +F + A D+G + SK VT+ +K+QN PSI + G + V I E+ +G + V D D G + C + + + + ++T ++ L T + D E ++ I D G PA +++ + + + D+NDN+P F Y FEENQP + + A D D G NA+L Y I + P L ++ N + + S LDRE+ + ++F+ V A D G P G+ TV ++++D NDN P F Y+ S E+ V + +D D G N V S+ + F + + + S DRE + S Y+F + A D +++ V ++I + D NDN P P S+YK +L P S T V+++ D D G+NS++ F + + LF I+ + GE+ + + H G L +K D G+P
Sbjct: 129 IEILDENDNTPQFSSPVLTLSIPENTHVGALFA-IPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKL-PQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSV-LQVKANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGIIFVKGSVDREEI-SILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQ-LRSASETGNDRKRKYFLQTTTLLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSV---PEGLFEINPNTGEVRVMSQLDREQL-DHYQFL----VAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLS---PVGMVTVNDHDEGENARVQLSVEPDN-GKFMIQNGTYTILSTISFDREKE-STYSFRLKAVDGGDP---PRSSYVGITINVLDENDNAPYVTKPANSSYK----FLDPRTSPETHVESVEAEDIDIGLNSELDFNIVGGNPHGLFRIS-SEGEITLAKEFTPKHIGLHRLVVKVKDKGTP 772 HSP 2 Score: 137.502 bits (345), Expect = 3.324e-32 Identity = 140/518 (27.03%), Postives = 237/518 (45.75%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKP--------IFESSFYTQSIDCNLEINSTLDL-KIHATDLDINANVTYRFSLNVPFIVQDCFDLN---PFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIP-VFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV 1884
+L I I D NDNVP++ ++ E+ EN+ + L++ KA DSD PN ++Y +P+S + S N GI + ++ +DRE IS + A D G SK+ + I + D NDN P + +I ++ + + + L ++ D NA VT + +VPF ++ + L+ L +E EYR I A+D G P S ++ + + + N P + P V ENQ G +L V D DSG + + SI + + +N E + ++S + DRE Q ++ D G P+ +A + + ++D NDN P+F Y +++ E P + +T +D D+G NA+++ ++ D K + I++ S DREK +++ A D G+P RS ++I ++D NDN P V + A + FL+ S + V A D D G+N ++ ++IV
Sbjct: 238 LLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQV-KANDSDMGPNGEVTYSLHQPSSPVMRLLSIDRNTGI---IFVKGSVDREEISILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGTAVALVEVSDRDEGENAVVTCVVAGDVPFQLRSASETGNDRKRKYFLQTTTLLDYERI-KEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAP-VFSPTLYEVEFFEENQP-GDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGE-VRVMSQL-----DREQLDHYQFLVAAADKGVPSLRGTATVVVKVLDRNDNDPKFMLNGYSFSVQENMPPLSPVGMVTVNDHDEGENARVQLSVEPDNG-----KFMIQNGTYTILSTISFDREK-----ESTYSFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPANSSYKFLDPRTSPET--HVESVEAEDIDIGLNSELDFNIV 730 HSP 3 Score: 112.849 bits (281), Expect = 1.078e-24 Identity = 118/449 (26.28%), Postives = 195/449 (43.43%), Query Frame = 1
Query: 1099 IRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQ-SLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIP----------VFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGE---------LYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQF-ILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+ I EN +G + V D DSG +G + ++ + ++ + + + LI DRE++ L I D G P +SA + I I D NDN P+FE+ Y + E + ++ Q+ A+D D G N ++ Y + +S +L+ ++ N II ++ S+DRE+ + + V A D+G +S V+I + D NDN P + NIS G+ VA+ D D G N VT + + +PF+L S L + L+D E + +Y I A DS L ++T S+ + + D NDN P+F + + Y+++ G V V A D DSG N+++ + I LF IN +GE+ + L + A D G P L + +++
Sbjct: 148 LSIPENTHVGALFAIPVATDRDSGSNGIADYALTTGPEATNLFSLQVAQDSDEKLPQLIVLGNLDRELRDSYDLNIKVVDGGSPPRQSSALLRITITDANDNVPKFERSHYEGELPENSPVGHSVLQVKANDSDMGPNGEVTYSLHQPSSPV--MRLLSIDRNTGIIFVKGSVDREEI-----SILKFYVQAKDNGPQSKSSKALVTITVKDQNDNAPSIRIRGIGLVTHEDGVANISEDMPVGT-----AVALVEVSDRDEGENAVVTCVVAGD--VPFQLRSASETGNDRKRKYFLQTTTLLDYE-RIKEYRIEIVAVDSGNPAL---SSTNSLKVQVTDMNDNAPVF---SPTLYEVEFFEENQPGDKVLDVVATDADSGTNAELTYSITGGSVPEGLFEINPNTGEVRVMSQLDREQLDHYQFLVAAADKGVPSLRGTATVVVKV 575
BLAST of Protocadherin alpha-11 vs. Ensembl Xenopus
Match: ENSXETT00000047801.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 229.18 bits (583), Expect = 7.431e-61 Identity = 220/770 (28.57%), Postives = 371/770 (48.18%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNK--LIKVESNCQII-AIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLED---FGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV--RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD--SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFP-NESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGEL-LTSTVLSVIHKGEETLFIKAIDCGSPR 2349
++ EN+ +G+++ L+ + P S +FKL+ ++E G+ S IDR+ +LC+ C + + ++++I+ L D NDN P + I I + ENT ++S Y +P A D D N I +Y++ F + ++ +G K P L +++ +DRE + + + DGG P+++ + L + + DVNDN+P+F+ +I + + +++ ++HATD D+ NA + + F + + + F ++ ++ VK+ L E + ++ ++ A D S+ TVT+++ + N PSI ++ N +++ E + I V D D+ ++GK C ++D+ + L T D E + I D GKP N SA + I I D NDN+P F + E N P + +++A D D G NA+L Y + PN + ++ I+ A++ LDREK R+ + VIA D+G P +TTV++ ++D NDN P F YN E+ +G+ V + D D G N VT S+V R+ F ++P +G + DRE Q S YTF + A D SP +K++TV V+I +ED NDN+P+F+ P N +Y + + P GS+V V AID D+GIN+ +++ + LF+I E SG + L +L+ H L IK D G P
Sbjct: 53 ELPENVLIGNLLKDLNLTLDPDLSTPLQFKLVYKTGDVPLIRVEENTGEIFTTSNRIDRE---KLCSGIFTENKCFYEVEVAVLPDEVFRLVKIRFLIEDINDNSPLFPSTVINISIPENTAVNSRY-SVPSAIDPDVGVNGIQHYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSV-TQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREE-SPYHKLTVLASDGSS--TPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFT----DHDVPFRLKPVFDNQFL---LETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSY-------MLGPNAPTIFNLDRRTGILTAVRKLDREKQD---RYT--FTVIAKDNGNPSLQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGT------VGLITVTDADSGENAVVTLSLVNARDN---FIIDPLTGVIRPNITFDREQQGS-YTFQVKALDKGSP-----QKSSTVKVTIFVEDVNDNKPVFVIPSNNYSYDLVQTSTSP-GSVVARVYAIDNDTGINADLRYSIIGGNSRGLFAIGERSGNITLKEKLLAGDHGVLYKLVIKVNDSGKPE 779 HSP 2 Score: 117.472 bits (293), Expect = 6.635e-26 Identity = 151/574 (26.31%), Postives = 248/574 (43.21%), Query Frame = 1
Query: 718 IIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAI-------LRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFN------CSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTI-----FEENQP-NFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPY--QVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTI 2376
I D+NDN P+F S+ SI N +NS + A D D+ N + L Q+ F L+ L V++SL E Y I D G P S + + + + N P + + + I E+ +G + D D G + K + + L +++ I N +I++ + DRE +L + D + A ++I I D+NDN P + + + E P N IA +T D D LN ++ D P +L V N Q L P + Y +++A+DSG+P + S + I++ D NDN PVF +SF+E+ K++ A D D G N +++Y + F L+ +G L + +DRE Q +YTF++ A+D+ L T TV++S++ D NDN P F NE N+ + + +P+ V L+ D DSG N+ + L + N F I+ +G + + +G T +KA+D GSP+ ++ ++TI
Sbjct: 147 IEDINDNSPLFPSTVINISIPENTAVNSRYSVP-SAIDPDVGVNGIQHYEL---LKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQ-KDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRP--VFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAI--------DNNTGLITV--KEPLDREESPYHKLTVLASDGSSTP--SRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDHDV----PFRLKPVFDN------QFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKIS---ATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQ-DRYTFTVIAKDNGNPSLQTNT-TVTLSVL--DQNDNSPSFTH-NEYNFYVPEN--LPMYGTVGLITVTDADSGENAVVTLSLVNARDN--FIIDPLTGVIRPNITFDREQQGSYTFQVKALDKGSPQKSSTVKVTI 679 HSP 3 Score: 89.7373 bits (221), Expect = 2.164e-17 Identity = 89/341 (26.10%), Postives = 148/341 (43.40%), Query Frame = 1
Query: 1390 DVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESN--CQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTY----SIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPI----FIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
D+NDNSP F + +I E N + +A D D G+N Y + +++ + + E + Q+I QSLDRE+ + ++ D G P RS + + + + D+NDN PVF++ ++ ED V A D D G N + + I F ++ N+G + + +DRE P + ++ A D + + +V+I I D NDN P +I N N +QLS P+ + + L+ DKD+ +N ++ + + L + + L T+ L E + I A D G P L L I+I
Sbjct: 149 DINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGVNGIQHYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQ-----KDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAV---GTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESP-YHKLTVLASDGSST-----PSRATVTINITDINDNIPSIDTRYII-NPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDHDVPFRLKPVFDNQFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKI 474
BLAST of Protocadherin alpha-11 vs. Ensembl Xenopus
Match: ENSXETT00000047798.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 228.794 bits (582), Expect = 8.749e-61 Identity = 220/770 (28.57%), Postives = 371/770 (48.18%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNK--LIKVESNCQII-AIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLED---FGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV--RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD--SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFP-NESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGEL-LTSTVLSVIHKGEETLFIKAIDCGSPR 2349
++ EN+ +G+++ L+ + P S +FKL+ ++E G+ S IDR+ +LC+ C + + ++++I+ L D NDN P + I I + ENT ++S Y +P A D D N I +Y++ F + ++ +G K P L +++ +DRE + + + DGG P+++ + L + + DVNDN+P+F+ +I + + +++ ++HATD D+ NA + + F + + + F ++ ++ VK+ L E + ++ ++ A D S+ TVT+++ + N PSI ++ N +++ E + I V D D+ ++GK C ++D+ + L T D E + I D GKP N SA + I I D NDN+P F + E N P + +++A D D G NA+L Y + PN + ++ I+ A++ LDREK R+ + VIA D+G P +TTV++ ++D NDN P F YN E+ +G+ V + D D G N VT S+V R+ F ++P +G + DRE Q S YTF + A D SP +K++TV V+I +ED NDN+P+F+ P N +Y + + P GS+V V AID D+GIN+ +++ + LF+I E SG + L +L+ H L IK D G P
Sbjct: 33 ELPENVLIGNLLKDLNLTLDPDLSTPLQFKLVYKTGDVPLIRVEENTGEIFTTSNRIDRE---KLCSGIFTENKCFYEVEVAVLPDEVFRLVKIRFLIEDINDNSPLFPSTVINISIPENTAVNSRY-SVPSAIDPDVGVNGIQHYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSV-TQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREE-SPYHKLTVLASDGSS--TPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFT----DHDVPFRLKPVFDNQFL---LETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSY-------MLGPNAPTIFNLDRRTGILTAVRKLDREKQD---RYT--FTVIAKDNGNPSLQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGT------VGLITVTDADSGENAVVTLSLVNARDN---FIIDPLTGVIRPNITFDREQQGS-YTFQVKALDKGSP-----QKSSTVKVTIFVEDVNDNKPVFVIPSNNYSYDLVQTSTSP-GSVVARVYAIDNDTGINADLRYSIIGGNSRGLFAIGERSGNITLKEKLLAGDHGVLYKLVIKVNDSGKPE 759 HSP 2 Score: 117.472 bits (293), Expect = 7.154e-26 Identity = 151/574 (26.31%), Postives = 249/574 (43.38%), Query Frame = 1
Query: 718 IIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAI-------LRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFN------CSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTI-----FEENQP-NFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPY--QVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTI 2376
I D+NDN P+F S+ SI N +NS + A D D+ N + L Q+ F L+ L V++SL E Y I D G P S + + + + N P + + + I E+ +G + D D G + K + + L +++ I N +I++ + DRE +L + D + + A ++I I D+NDN P + + + E P N IA +T D D LN ++ D P +L V N Q L P + Y +++A+DSG+P + S + I++ D NDN PVF +SF+E+ K++ A D D G N +++Y + F L+ +G L + +DRE Q +YTF++ A+D+ L T TV++S++ D NDN P F NE N+ + + +P+ V L+ D DSG N+ + L + N F I+ +G + + +G T +KA+D GSP+ ++ ++TI
Sbjct: 127 IEDINDNSPLFPSTVINISIPENTAVNSRYSVP-SAIDPDVGVNGIQHYEL---LKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQ-KDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRP--VFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAI--------DNNTGLITV--KEPLDREESPYHKLTVLASDGS--STPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDHDV----PFRLKPVFDN------QFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKIS---ATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQ-DRYTFTVIAKDNGNPSLQTNT-TVTLSVL--DQNDNSPSFTH-NEYNFYVPEN--LPMYGTVGLITVTDADSGENAVVTLSLVNARDN--FIIDPLTGVIRPNITFDREQQGSYTFQVKALDKGSPQKSSTVKVTI 659 HSP 3 Score: 89.7373 bits (221), Expect = 2.195e-17 Identity = 89/341 (26.10%), Postives = 148/341 (43.40%), Query Frame = 1
Query: 1390 DVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESN--CQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTY----SIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPI----FIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
D+NDNSP F + +I E N + +A D D G+N Y + +++ + + E + Q+I QSLDRE+ + ++ D G P RS + + + + D+NDN PVF++ ++ ED V A D D G N + + I F ++ N+G + + +DRE P + ++ A D + + +V+I I D NDN P +I N N +QLS P+ + + L+ DKD+ +N ++ + + L + + L T+ L E + I A D G P L L I+I
Sbjct: 129 DINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGVNGIQHYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQ-----KDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAV---GTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESP-YHKLTVLASDGSST-----PSRATVTINITDINDNIPSIDTRYII-NPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDHDVPFRLKPVFDNQFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKI 454
BLAST of Protocadherin alpha-11 vs. Ensembl Xenopus
Match: ENSXETT00000047804.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 228.409 bits (581), Expect = 1.149e-60 Identity = 220/770 (28.57%), Postives = 371/770 (48.18%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNK--LIKVESNCQII-AIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLED---FGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV--RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD--SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFP-NESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGEL-LTSTVLSVIHKGEETLFIKAIDCGSPR 2349
++ EN+ +G+++ L+ + P S +FKL+ ++E G+ S IDR+ +LC+ C + + ++++I+ L D NDN P + I I + ENT ++S Y +P A D D N I +Y++ F + ++ +G K P L +++ +DRE + + + DGG P+++ + L + + DVNDN+P+F+ +I + + +++ ++HATD D+ NA + + F + + + F ++ ++ VK+ L E + ++ ++ A D S+ TVT+++ + N PSI ++ N +++ E + I V D D+ ++GK C ++D+ + L T D E + I D GKP N SA + I I D NDN+P F + E N P + +++A D D G NA+L Y + PN + ++ I+ A++ LDREK R+ + VIA D+G P +TTV++ ++D NDN P F YN E+ +G+ V + D D G N VT S+V R+ F ++P +G + DRE Q S YTF + A D SP +K++TV V+I +ED NDN+P+F+ P N +Y + + P GS+V V AID D+GIN+ +++ + LF+I E SG + L +L+ H L IK D G P
Sbjct: 53 ELPENVLIGNLLKDLNLTLDPDLSTPLQFKLVYKTGDVPLIRVEENTGEIFTTSNRIDRE---KLCSGIFTENKCFYEVEVAVLPDEVFRLVKIRFLIEDINDNSPLFPSTVINISIPENTAVNSRY-SVPSAIDPDVGVNGIQHYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSV-TQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREE-SPYHKLTVLASDGSS--TPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFT----DHDVPFRLKPVFDNQFL---LETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSY-------MLGPNAPTIFNLDRRTGILTAVRKLDREKQD---RYT--FTVIAKDNGNPSLQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGT------VGLITVTDADSGENAVVTLSLVNARDN---FIIDPLTGVIRPNITFDREQQGS-YTFQVKALDKGSP-----QKSSTVKVTIFVEDVNDNKPVFVIPSNNYSYDLVQTSTSP-GSVVARVYAIDNDTGINADLRYSIIGGNSRGLFAIGERSGNITLKEKLLAGDHGVLYKLVIKVNDSGKPE 779 HSP 2 Score: 116.701 bits (291), Expect = 9.792e-26 Identity = 151/574 (26.31%), Postives = 248/574 (43.21%), Query Frame = 1
Query: 718 IIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAI-------LRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFN------CSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTI-----FEENQP-NFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPY--QVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTI 2376
I D+NDN P+F S+ SI N +NS + A D D+ N + L Q+ F L+ L V++SL E Y I D G P S + + + + N P + + + I E+ +G + D D G + K + + L +++ I N +I++ + DRE +L + D + A ++I I D+NDN P + + + E P N IA +T D D LN ++ D P +L V N Q L P + Y +++A+DSG+P + S + I++ D NDN PVF +SF+E+ K++ A D D G N +++Y + F L+ +G L + +DRE Q +YTF++ A+D+ L T TV++S++ D NDN P F NE N+ + + +P+ V L+ D DSG N+ + L + N F I+ +G + + +G T +KA+D GSP+ ++ ++TI
Sbjct: 147 IEDINDNSPLFPSTVINISIPENTAVNSRYSVP-SAIDPDVGVNGIQHYEL---LKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQ-KDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRP--VFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAI--------DNNTGLITV--KEPLDREESPYHKLTVLASDGSSTP--SRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDHDV----PFRLKPVFDN------QFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKIS---ATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQ-DRYTFTVIAKDNGNPSLQTNT-TVTLSVL--DQNDNSPSFTH-NEYNFYVPEN--LPMYGTVGLITVTDADSGENAVVTLSLVNARDN--FIIDPLTGVIRPNITFDREQQGSYTFQVKALDKGSPQKSSTVKVTI 679 HSP 3 Score: 89.3521 bits (220), Expect = 2.577e-17 Identity = 89/341 (26.10%), Postives = 148/341 (43.40%), Query Frame = 1
Query: 1390 DVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESN--CQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTY----SIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPI----FIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
D+NDNSP F + +I E N + +A D D G+N Y + +++ + + E + Q+I QSLDRE+ + ++ D G P RS + + + + D+NDN PVF++ ++ ED V A D D G N + + I F ++ N+G + + +DRE P + ++ A D + + +V+I I D NDN P +I N N +QLS P+ + + L+ DKD+ +N ++ + + L + + L T+ L E + I A D G P L L I+I
Sbjct: 149 DINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGVNGIQHYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQ-----KDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAV---GTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESP-YHKLTVLASDGSST-----PSRATVTINITDINDNIPSIDTRYII-NPVNGTVQLSEKAPLNTKIALITVTDKDADLNGKVTCFTDHDVPFRLKPVFDNQFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKI 474
BLAST of Protocadherin alpha-11 vs. Ensembl Xenopus
Match: ENSXETT00000027070.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:19099783:19110965:-1 gene:ENSXETG00000013163.1 transcript:ENSXETT00000027070.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 224.172 bits (570), Expect = 9.980e-60 Identity = 234/825 (28.36%), Postives = 388/825 (47.03%), Query Frame = 1
Query: 127 IFENLPVGSVICKLSN--VIIPRPSDTTKFKLI---KNRFF--QIENGDNLKVSGLIDRDDNLELCAYRN---VNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLD--INANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAH--DPDFGVNGDVTYSIVRETL--LPF----KLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVP----VGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE-FRNPDSTPFNETEESFLSDQATFIIVGII--LGTFFICCGLVTGI 2517
I+E +G VI ++N + + KF ++ K ++ +ENGD L V+ IDR+ LC + +N + L T N ++I D NDN P +S++ I + E + + + L A+D D N+I YK+ + YF + + + G K P L L + +DRE + + L A DGGTPSKTG+ + I + D+NDN P+F Y ++ N+ I L + +HATD D NA +TY F+ ++P Q+ F +NP N +++ L +E A+ Y +++A D G V K + + N N P IL+ + +I E+ +G VI + D DSG +G+ I E + +I S + L+T+ DRE + + I +D G P S I +I+ DVNDN+P F+K Y I E N + ++ A D D N ++ Y I L D + I + S I + + + + + + + A D G PQ + + T+ + L D+NDN PVF++ Y ++++++ N + F H D D NG V Y I+ + + +P +N SG LY+ D E+ ++ + A+DS + ++A +V I I D NDN P ++P++ + + +P G LVT V A+D DSG N+ + + L + I + +GE+ + L + + + D G P L++ L + + E F+ N+ ++ S ATF +V I + FI LV I
Sbjct: 38 IYEEQRLGYVIGNIANDLGVSAEELSSRKFHIVSRSKKQYLNVHLENGD-LYVADRIDRE---ALCGMQQNCFLNIEAVMESPLHFYTIN-----VEIQDVNDNSPSFSKSIFEISISELAVVGT-HFALGSAKDPDLGNNSIQSYKLS-ANDYFGMLEKVNTDGRKYPELVLEKTLDREKKNSSVLILSAFDGGTPSKTGTSLIRIVVTDINDNYPLFNKDTYRVTVSENVPI-GFLVIDLHATDADEGSNAEITYLFN-DIPENAQEVFAINPENGSVQITGKLDYEV-ATNYEMTVEAKDGGGLVSYCKLLIQVSDVNDN--APDILITSFSDIIP--EDSRVGTVIALVNLDDLDSGENGEVVGQISESLPFHLI-------SSSGNYYKLVTSMDLDREKTSEYNITIKAEDKGSPQLTNSKTIRLILTDVNDNAPVFDKMDYVAYIQENNPSGNSFYRVHATDPDINENGKVVYMI-----LTDIIEDIPISSYVSINTVSGVLYAQRSFDYEKLREFYIQAEDKGSPQLTNNKTIRLILTDVNDNAPVFEKMDY-VAYIQE----NNPSGSSFFRVHATDSDINENGKVVYMILTDIIEDMPLSSYISINTVSGVLYAQRSFDYESL-REFYIQVMAKDSGSP---SRSANATVKICITDQNDNAPKILYPSQDSEAASVFEFIPHFSTKGYLVTKVVAVDADSGHNAWLSYHLLQVPDPSFLIIGQNTGEIRITRDLQETDALRQRIVVMVKDNGYPMLSSTVTLNLVVAENFQQVLPEITNQHIDTESSSNATFYLVISIALISILFIFTVLVAVI 823
BLAST of Protocadherin alpha-11 vs. Ensembl Xenopus
Match: vapa (VAMP associated protein A [Source:Xenbase;Acc:XB-GENE-990155]) HSP 1 Score: 217.238 bits (552), Expect = 4.196e-57 Identity = 193/671 (28.76%), Postives = 320/671 (47.69%), Query Frame = 1
Query: 367 LKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV-GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPR 2349
++++I+I+ D NDN P + I I + ENT ++S + +P A D D N + +Y++ F + ++ +G K P L +++ +DRE + + + DGGTP K+ + L + + DVNDNKP+F+ S I N I +++ +++HATD DI NA + Y F V + F LN ++ V++ L E A ++ ++ A D ++ TVT+++ + N PP+I ++ N + + E I I V D D+ ++ K C I + + K +N + L T+ + D E I D GKP+ N +A + + + D NDN P F + ++ E N+ + ++A D D G N+ + Y++ + S +D ++ V + A + DRE+ RF+ + V A D+G P V + ++D NDN P F + E+ V V A D D G N VT SI+ + F L+P SG + S DRE Q S YTF + A D +++T V+I I D NDN P+ I P SN +L L + GS+V V A+D D+G+N+++++ + LF I+ +G + S G L + D G P+
Sbjct: 123 FRLIKIKIIVKDTNDNAPMFPSTVINISIPENTLINSRF-PIPSAVDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNKPVFKESQVEVHIPENAPIGTSV-VQLHATDADIGSNAEIKYIFGAQVTSATKRLFALNNTTGLITVQRPLDREETAV-HKLTVLATDGSS--TPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPINTKIALITVSDKDTDVNSKVICFIEREVPFHL-----KAVYDNQYL--LETSSLLDYEGIKEFSFKIVAADTGKPSLNQTALVRVELEDENDNPPIFSQPVIELSVSENNRRGLYLTTVSASDEDSGKNSDIVYQLGPNASFFDLDRKTGV-----LTASRVFDREEQE---RFI--FTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENL---PKYSTVGVITATDSDAGENKAVTLSILNDN-ENFVLDPYSGLIKSNVSFDREQQ-SSYTFDVKAVDGGQP---PRSSTAKVTINIMDANDNSPVVISP-PSNTSFKLVPLSAIPGSVVAEVFAVDTDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPSAADVGLHRLVVNISDLGYPK 762 HSP 2 Score: 116.316 bits (290), Expect = 1.335e-25 Identity = 151/578 (26.12%), Postives = 249/578 (43.08%), Query Frame = 1
Query: 712 IKII--DVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAI-------LRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGK----FNCSILEPKNYDIILTMNKTKSENIAIISLIT-NKIFDREVKTRIQLIIFCKDFGK-PAFNTSAEXXXXXXDVNDNSPQFEKEFY----HYTIF--EENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
IKII D NDN P+F S+ SI N INS + A D D N + L Q F L+ L V+++L E Y I D G P + S + + + + N P + + + I EN IG ++ D D G + + F + + +N T LIT + DRE +L + D PA A ++I + DVNDN P + + + T++ E++ N IA +T D D +N+++ I+ + P L V N ++ SL + F F +++A D+G+P + + V +EL D NDN P+F Q +S E+ + + A D D G N D+ Y + F L+ +G L + + DRE Q ++ F++TARD+ T L + A + + + D NDN P F ++++ +S +P S V ++ A D D+G N + + + N F ++ SG + ++ + T +KA+D G P ++ ++TI I
Sbjct: 128 IKIIVKDTNDNAPMFPSTVINISIPENTLINSRFPIP-SAVDPDTGFNGVQHYEL---LNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQ-KDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNKP--VFKESQVEVHIPENAPIGTSVVQLHATDADIGSNAEIKYIFGAQVTSATKR--LFALNNT-------TGLITVQRPLDREETAVHKLTVLATDGSSTPA---RATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPINTKIALITVSDKDTDVNSKVICFIEREV----PFHLKAVYDNQYLLETSSLLDYEGIKEFSF----KIVAADTGKPSLNQTALVRVELEDENDNPPIFSQPVIELSVSEN---NRRGLYLTTVSASDEDSGKNSDIVYQLGPNASF-FDLDRKTGVLTASRVFDREEQ-ERFIFTVTARDNGTPPLQSQAAVI---VTVLDENDNSPKF---THNHFQFFVSENLPKYSTVGVITATDSDAGENKAVTLSILNDNEN--FVLDPYSGLIKSNVSFDREQQSSYTFDVKAVDGGQPPRSSTAKVTINI 665
BLAST of Protocadherin alpha-11 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 237.269 bits (604), Expect = 1.039e-63 Identity = 222/762 (29.13%), Postives = 361/762 (47.38%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIENGDN--LKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV---GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G IDR+ +LCA ++ C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN PIF SI N I S++ ++HATD DI NA + + FS V I + F LN ++ VK+ L E S ++ + A D G ++ TV +++ + N PSI ++ N + + EN + I V D DS +G+ C ++++ + S L T D E + + D GKP N S+ + I + D NDN+P F + F ++ E N P + +++A D D G NA++ Y + +D P + + + A++ LDREK + + V+A D+G P + TV + ++D NDN P+F YN E S V + DPD+G N VT SI+ + F ++P SG + DRE Q S YTF + A D +++T V+I + D NDN+PIFI P SNY + +++P G++V V AID D G+N+++ + + LF I +TSG + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDRE---KLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRY-SLPAAIDPDIGINGVQNYQLIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSV-TQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPS-HKLLVLATDGGS--TPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCF----TDHEVPFRLRPVFSNQFL---LETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDA----PPEFNLDQRTGILTAVKKLDREKQEKYY-----FTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPE---SLPKHGTVGLITVTDPDYGENSAVTLSIL-DVNDQFTIDPQSGVIRPNISFDRERQES-YTFYVKAEDGGR---VSRSSTARVTINVVDVNDNKPIFIDP-PSNYSFE--WVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 236.498 bits (602), Expect = 3.130e-63 Identity = 222/762 (29.13%), Postives = 361/762 (47.38%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIENGDN--LKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV---GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G IDR+ +LCA ++ C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN PIF SI N I S++ ++HATD DI NA + + FS V I + F LN ++ VK+ L E S ++ + A D G ++ TV +++ + N PSI ++ N + + EN + I V D DS +G+ C ++++ + S L T D E + + D GKP N S+ + I + D NDN+P F + F ++ E N P + +++A D D G NA++ Y + +D P + + + A++ LDREK + + V+A D+G P + TV + ++D NDN P+F YN E S V + DPD+G N VT SI+ + F ++P SG + DRE Q S YTF + A D +++T V+I + D NDN+PIFI P SNY + +++P G++V V AID D G+N+++ + + LF I +TSG + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDRE---KLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRY-SLPAAIDPDIGINGVQNYQLIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSV-TQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPS-HKLLVLATDGGS--TPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCF----TDHEVPFRLRPVFSNQFL---LETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDA----PPEFNLDQRTGILTAVKKLDREKQEKYY-----FTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPE---SLPKHGTVGLITVTDPDYGENSAVTLSIL-DVNDQFTIDPQSGVIRPNISFDRERQES-YTFYVKAEDGGR---VSRSSTARVTINVVDVNDNKPIFIDP-PSNYSFE--WVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 236.113 bits (601), Expect = 9.174e-63 Identity = 222/762 (29.13%), Postives = 361/762 (47.38%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIENGDN--LKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV---GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G IDR+ +LCA ++ C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN PIF SI N I S++ ++HATD DI NA + + FS V I + F LN ++ VK+ L E S ++ + A D G ++ TV +++ + N PSI ++ N + + EN + I V D DS +G+ C ++++ + S L T D E + + D GKP N S+ + I + D NDN+P F + F ++ E N P + +++A D D G NA++ Y + +D P + + + A++ LDREK + + V+A D+G P + TV + ++D NDN P+F YN E S V + DPD+G N VT SI+ + F ++P SG + DRE Q S YTF + A D +++T V+I + D NDN+PIFI P SNY + +++P G++V V AID D G+N+++ + + LF I +TSG + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDRE---KLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRY-SLPAAIDPDIGINGVQNYQLIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSV-TQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPS-HKLLVLATDGGS--TPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFT----DHEVPFRLRPVFSNQFL---LETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDA----PPEFNLDQRTGILTAVKKLDREKQEKYY-----FTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPE---SLPKHGTVGLITVTDPDYGENSAVTLSIL-DVNDQFTIDPQSGVIRPNISFDRERQES-YTFYVKAEDGGR---VSRSSTARVTINVVDVNDNKPIFIDP-PSNYSFE--WVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 235.728 bits (600), Expect = 1.097e-62 Identity = 222/762 (29.13%), Postives = 361/762 (47.38%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIENGDN--LKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV---GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G IDR+ +LCA ++ C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN PIF SI N I S++ ++HATD DI NA + + FS V I + F LN ++ VK+ L E S ++ + A D G ++ TV +++ + N PSI ++ N + + EN + I V D DS +G+ C ++++ + S L T D E + + D GKP N S+ + I + D NDN+P F + F ++ E N P + +++A D D G NA++ Y + +D P + + + A++ LDREK + + V+A D+G P + TV + ++D NDN P+F YN E S V + DPD+G N VT SI+ + F ++P SG + DRE Q S YTF + A D +++T V+I + D NDN+PIFI P SNY + +++P G++V V AID D G+N+++ + + LF I +TSG + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDRE---KLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRY-SLPAAIDPDIGINGVQNYQLIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSV-TQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPS-HKLLVLATDGGS--TPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFT----DHEVPFRLRPVFSNQFL---LETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDA----PPEFNLDQRTGILTAVKKLDREKQEKYY-----FTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPE---SLPKHGTVGLITVTDPDYGENSAVTLSIL-DVNDQFTIDPQSGVIRPNISFDRERQES-YTFYVKAED---GGRVSRSSTARVTINVVDVNDNKPIFIDP-PSNYSFE--WVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. Ensembl Mouse
Match: Pcdh11x (protocadherin 11 X-linked [Source:MGI Symbol;Acc:MGI:2442849]) HSP 1 Score: 235.343 bits (599), Expect = 1.539e-62 Identity = 222/762 (29.13%), Postives = 361/762 (47.38%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIENGDN--LKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV---GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G IDR+ +LCA ++ C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN PIF SI N I S++ ++HATD DI NA + + FS V I + F LN ++ VK+ L E S ++ + A D G ++ TV +++ + N PSI ++ N + + EN + I V D DS +G+ C ++++ + S L T D E + + D GKP N S+ + I + D NDN+P F + F ++ E N P + +++A D D G NA++ Y + +D P + + + A++ LDREK + + V+A D+G P + TV + ++D NDN P+F YN E S V + DPD+G N VT SI+ + F ++P SG + DRE Q S YTF + A D +++T V+I + D NDN+PIFI P SNY + +++P G++V V AID D G+N+++ + + LF I +TSG + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPDKSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDRE---KLCAGIVLDARCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPTTVINISIPENSAINSRY-SLPAAIDPDIGINGVQNYQLIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVADTNDNHPIFIEKEIEVSIPENAPIGSSV-TQLHATDADIGENARIHFYFSNLVSNIAKRLFHLNTTTGLITVKEPLDREESPS-HKLLVLATDGGS--TPARATVLVNVTDINDNVPSIDIRYIVNPTNGTVLLSENAPLNTKIALITVMDKDSEHNGRVTCFT----DHEVPFRLRPVFSNQFL---LETAAFLDFESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQSFISLSVPENNSPGAQLTKISATDADSGQNAEISYMLGFDA----PPEFNLDQRTGILTAVKKLDREKQEKYY-----FTVLAQDNGIPPLMSNATVFVTVLDQNDNSPIFTHNEYNFYVPE---SLPKHGTVGLITVTDPDYGENSAVTLSIL-DVNDQFTIDPQSGVIRPNISFDRERQES-YTFYVKAEDG---GRVSRSSTARVTINVVDVNDNKPIFIDP-PSNYSFE--WVLPSTNPGTVVFKVVAIDDDIGMNAEVLYSIVGGNTKGLFMIEQTSGNITLKEKCMVSDLGLHRVIVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. UniProt/SwissProt
Match: sp|Q6KEQ9|PC11X_PIG (Protocadherin-11 X-linked OS=Sus scrofa OX=9823 GN=PCDH11X PE=2 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 8.843e-61 Identity = 214/763 (28.05%), Postives = 360/763 (47.18%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIENGDN--LKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVP----VGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G IDR+ +LCA V+ C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP D D N + Y + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN+P+F+ + SI N + S++ ++HATD DI NA + + FS + + + F LN ++ +K+ L E + ++ + A D G ++ V + N N+ PSI ++ N + + EN + I V D D+ +G +C ++++ + S L T D E + + D GKP N S+ + I + D NDN+P F + F ++ E N P + +++A D D G NA++ Y + +D P++ + A++ LDREK + F V+A D+G P + TV + ++D NDN PVF YN E+ V + DPD+G N V SI+ + F ++P +G + DRE Q S YTF + A D +++T V+I + D NDN+P+F+ P+ SNY + LVP G++V V AID D+G+N+++++ + LF I++TSG + G L +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPDRSLTTPMQFKLVYKTGDVPLIRIEEGTGEIFTTGARIDRE---KLCAGIVVDAHCFYEVEVAVLPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSRY-ALPATIDPDTGINGVQNYHLIKGQSIFGLDVIETPEGEKMPQLIVQKELDREEKDTYVMKIKVEDGGFPQRSSTAILQVSVADTNDNRPVFKENEIEVSIPENAPVGSSV-TQLHATDADIGENAKIHFYFSNLISNMAKKLFHLNSTTGLITIKEPLDREE-SPNHKLLVLASDGGLTPARAMVLVNVTDINDNI--PSIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGWVSCFT----DHEVPFRLRPVFSNQFL---LETAAYLDYESTREYAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQPFLSLSVPENNSPGTQLTKISAMDADSGRNAEINYLLGFDA----PSEFNLDHRTGILTAVKKLDREKQ-EKYSFT----VLAKDNGMPPLMTNATVLVTVLDQNDNSPVFTHNEYNFYVPENL---PRHGTVGLITVTDPDYGENSAVILSIL-DANDDFTIDPQTGVIQPNISFDREKQES-YTFYVKAEDGGR---ISRSSTAKVTINVVDVNDNKPVFVVPS-SNYSFE---LVPPSTNPGTVVFTVVAIDNDTGMNAELRYSMVGGNTKGLFIIDQTSGNITLKEKCVFADLGLHRLVVKAKDLGQP 759
BLAST of Protocadherin alpha-11 vs. UniProt/SwissProt
Match: sp|Q71M42|PC11X_PANTR (Protocadherin-11 X-linked OS=Pan troglodytes OX=9598 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 229.565 bits (584), Expect = 8.612e-60 Identity = 215/763 (28.18%), Postives = 363/763 (47.58%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL-----PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV---GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G+ IDR+ +LCA + C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN P+F+ + SI N + +++ ++HATD DI NA + + FS V I + F LN ++ +K+ L E ++ + A D G ++ V + N N+ PSI + P N+ V+ + EN + I V D D+ +G+ C +++I + S L T D E + + D GKP N SA + I + D NDN+P F + F +I E N P + +++A D D G NA++ Y + D P + + ++ LDREK + + F ++A D+G P + + TV + ++D NDN PVF YN E+ V + DPD+G N VT SI+ E F ++ +G + DRE Q S YTF + A D ++++ V+I + D NDN+P+FI P SNY +L ++P G++V V A+D D+G+N+++++ + LF+I++ +G + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDRE---KLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT-LPAAVDPDVGTNGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV-TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE-ETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNV--PSIDIRYIVNPVNDTVV-LSENIPLNTKIALITVTDKDADHNGRVTCFT----DHEIPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDA----PPEFSLDRRTGMLTVVKKLDREKE-DKYLFT----ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGT---VGLITVTDPDYGDNSAVTLSILDEN-DDFTIDSQTGVIRPNISFDREKQES-YTFYVKAEDGGR---VSRSSSAKVTINVVDVNDNKPVFIVP-PSNYSYEL--VLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. UniProt/SwissProt
Match: sp|Q6WYY1|PC11X_PANPA (Protocadherin-11 X-linked OS=Pan paniscus OX=9597 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 229.18 bits (583), Expect = 9.648e-60 Identity = 215/763 (28.18%), Postives = 363/763 (47.58%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL-----PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV---GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G+ IDR+ +LCA + C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN P+F+ + SI N + +++ ++HATD DI NA + + FS V I + F LN ++ +K+ L E ++ + A D G ++ V + N N+ PSI + P N+ V+ + EN + I V D D+ +G+ C +++I + S L T D E + + D GKP N SA + I + D NDN+P F + F +I E N P + +++A D D G NA++ Y + D P + + ++ LDREK + + F ++A D+G P + + TV + ++D NDN PVF YN E+ V + DPD+G N VT SI+ E F ++ +G + DRE Q S YTF + A D ++++ V+I + D NDN+P+FI P SNY +L ++P G++V V A+D D+G+N+++++ + LF+I++ +G + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDRE---KLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT-LPAAVDPDVGTNGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV-TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE-ETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNV--PSIDIRYIVNPVNDTVV-LSENIPLNTKIALITVTDKDADHNGRVTCFT----DHEIPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDA----PPEFSLDRRTGMLTVVKKLDREKE-DKYLFT----ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGT---VGLITVTDPDYGDNSAVTLSILDEN-DDFTIDSQTGVIRPNISFDREKQES-YTFYVKAEDGGR---VSRSSSAKVTINVVDVNDNKPVFIVP-PSNYSYEL--VLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. UniProt/SwissProt
Match: sp|Q6X862|PC11X_GORGO (Protocadherin-11 X-linked OS=Gorilla gorilla gorilla OX=9595 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 228.794 bits (582), Expect = 1.309e-59 Identity = 215/763 (28.18%), Postives = 363/763 (47.58%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL-----PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV---GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G+ IDR+ +LCA + C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN P+F+ + SI N + +++ ++HATD DI NA + + FS V I + F LN ++ +K+ L E ++ + A D G ++ V + N N+ PSI + P N+ V+ + EN + I V D D+ +G+ C +++I + S L T D E + + D GKP N SA + I + D NDN+P F + F +I E N P + +++A D D G NA++ Y + D P + + ++ LDREK + + F ++A D+G P + + TV + ++D NDN PVF YN E+ V + DPD+G N VT SI+ E F ++ +G + DRE Q S YTF + A D ++++ V+I + D NDN+P+FI P SNY +L ++P G++V V A+D D+G+N+++++ + LF+I++ +G + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDRE---KLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT-LPAAVDPDVGINGVQNYELIKSQNMFGLDVIETPEGDKMPQLIVQKELDREKKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV-TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE-ETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNV--PSIDIRYIVNPVNDTVV-LSENIPLNTKIALITVTDKDADHNGRVTCFT----DHEIPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDA----PPEFSLDRRTGMLTVVKKLDREKE-DKYLFT----ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGT---VGLITVTDPDYGDNSAVTLSILDEN-DDFTIDSQTGVIRPNISFDREKQES-YTFYVKAEDGGR---VSRSSSAKVTINVVDVNDNKPVFIVP-PSNYSYEL--VLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. UniProt/SwissProt
Match: sp|Q9BZA7|PC11X_HUMAN (Protocadherin-11 X-linked OS=Homo sapiens OX=9606 GN=PCDH11X PE=2 SV=1) HSP 1 Score: 228.409 bits (581), Expect = 1.824e-59 Identity = 214/764 (28.01%), Postives = 365/764 (47.77%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTT--KFKLIKNR----FFQIE--NGDNLKVSGLIDRDDNLELCAYRNVNFSCIWR-GILFCGTNNLKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL-----PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQ---IIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIF-PNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
++ EN+ +G ++ L+ +IP S TT +FKL+ +IE G+ IDR+ +LCA + C + + ++++I+ L D NDN P + I I + EN+ ++S Y LP A D D N + Y++ + F + ++ +G K P L +++ +DRE + + + DGG P ++ + L + + D NDN P+F+ + SI N + +++ ++HATD DI NA + + FS V I + F LN ++ +K+ L E ++ + A D G ++ V + N N+ PSI + P N+ V+ + EN + I V D D+ +G+ C +++I + S L T D E + + D GKP N SA + I + D NDN+P F + F +I E N P + +++A D D G NA++ Y L P+ + +C+ + ++ LDREK + + F ++A D+G P + + TV + ++D NDN PVF YN E+ V + DPD+G N VT SI+ E F ++ +G + DRE Q S YTF + A D ++++ V+I + D NDN+P+FI P+ +Y++ L P G++V V A+D D+G+N+++++ + LF+I++ +G + V G + +KA D G P
Sbjct: 33 EMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDRE---KLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT-LPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV-TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDRE-ETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNV--PSIDIRYIVNPVNDTVV-LSENIPLNTKIALITVTDKDADHNGRVTCFT----DHEIPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-------LLGPDAPPEFSLDCRTGMLTVVKKLDREKE-DKYLFT----ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGT---VGLITVTDPDYGDNSAVTLSILDEN-DDFTIDSQTGVIRPNISFDREKQES-YTFYVKAEDGGR---VSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 759
BLAST of Protocadherin alpha-11 vs. TrEMBL
Match: A0A4E0RYN8 (Putative protocadherin alpha OS=Fasciola hepatica OX=6192 GN=D915_000027 PE=4 SV=1) HSP 1 Score: 372.474 bits (955), Expect = 9.425e-105 Identity = 261/846 (30.85%), Postives = 415/846 (49.05%), Query Frame = 1
Query: 133 ENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI----EPTSKYFFI---------------SSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLK--------------------------IHATDLD--INANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSIL-----------------LPGNNA-----VIRIIENQDIGVVILTG-VVKDNDSGMDGKFNC----SILEPKNY-----DIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTT-VSIELMDINDNIPVFQQAFYNISFLEDFGSKKN-SRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD-------------------SPTNLLYR-------KTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPR 2349
EN P +VI +L + I P+P+ ++ + +N +F I +++V GL+DRD+N +LC + C+W + G L + I D NDNVP W+++SI I V E + +F ELP A+D D N I YK+ E ++ I S+E + K FL++ + +DRE HN+TLLA DG P TG L ++++++D ND+ P F SS YT + + + S + L+ + ATD D N + Y F+ + V D F L+ ++ +RV K L ++ + ++F + A D GRP S TTV + LK+ N + P I +P A VI I EN + L V D D+G G+F+C S + N+ D L K N + SL + DRE +L++ C D G+P +T ++++I++D NDN+PQF ++ Y + + E N+PN ++ +L AHD DDG N ++ YRI W + ++ + ++I ++LDRE P G++F QVIA D G+P+ T V + L DIND P F Q YN + ED+ R V A D D G+NG V Y ++ + LPF++ N G L + +DRE + + Y+ ++ ARD T++ R +T+ V I + D ND+ PIF++PN S+Y++++S G ++T + A+DKD+G N QI++ + + + LF + +GEL LS +KG L ++A D G+P+
Sbjct: 71 ENTPNLTVIGRLVDSIRPKPNQNLRYTIPQNPYFDISPESSVRVIGLLDRDENRQLCTEPSYPQQCVWTSFVVTGNGQYIGLRVVINDVNDNVPAWAESSITIHVTEEMQT-TFSAELPVAKDPDLDKNGIQGYKLQTELEDAERFELIVKSSAVKSGVRFSIDSAETLSSRFKLFLQVLKPLDRETQPRHNLTLLAFDGSEPYHTGRLNIIVEVVDENDHSPQFTSSAYTAVVSEDASVGSDIPLQESTSVAVKQSDSGGFVPPSYVDRVSQMRATDRDEGPNGQIQYEFAASTDPQVLDLFTLDQYSGRIRVAKPLSYDIRPTGWKFQVLAKDGGRPSRSSSTTVVIQLKDANTHGPEIKTRLHEPKPFFEGITRLGIPSAPAEHITNVIYIPENTPPVLEPLAVFTVGDKDTGTGGEFDCVLTDSEMSASNHADGSADFRLNFT-AKLPNWNVYSLYVIRSIDREAAPVRELVVTCTDHGEPPRSTYEKLNVILVDENDNAPQFTQKTYQFHVLEGNRPNASVGKLRAHDPDDGPNGRVTYRIVWPPTQPISDRPFLIAEGGKLIVTKTLDREANPKGYKF----QVIAADGGKPRPLNDTAEVEVILDDINDCTPQFSQKHYNFTIEEDYAQNFTIGRFVGRVQAVDCDLGLNGAVQY-VILDPGLPFEITSN-GMLKTTRYIDREMR-AVYSLTVLARDGGNEGDADLDEELQEYRTAGSTDMFNRAINDQKVRTSAAQVQITVTDVNDHYPIFVYPNASSYQVRISMHEKRGFIITRLVAVDKDTGPNGQIRYGIIKGNQLGLFKVRPDTGELYLDRPLSAEYKGNLVLIVEASDLGTPK 907
BLAST of Protocadherin alpha-11 vs. TrEMBL
Match: A0A267F7Y4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030061g1 PE=4 SV=1) HSP 1 Score: 336.265 bits (861), Expect = 4.073e-94 Identity = 246/796 (30.90%), Postives = 406/796 (51.01%), Query Frame = 1
Query: 214 LIKNRFFQI-ENGDNLKVSGLIDRD-DNLELCAYRN--VNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFF--ISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFA-SEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQF--EKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSI-VRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNES-NYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQAT--FIIVGIILGTFFICCGLVTGICTMAYRRWHSSNN 2556
+K+ +F + ++ + V IDRD D ELC + +N SC+ + ++ I I D ND+ PQW + + + EN + ++ P A D D N+++ Y++ P S F ++++ + P L +++ +DRE+ +++N TL A DGG + S+ L + ++DVND P+F+ + Y S+ + T+ L + ATD DI N NV+YRF+ P ++ FD+ ++ + V+ S K + +Y FS+ A D G ++ + +V +++ + N P I L + AV ++EN+ + ++T +V D D+G G+F+CSI + + Y + +N +S + T DRE + C D G P S +++ ++D ND+ P F ++ E N P + +TA D D G NA+L Y+I W +S N ++++N I A ++LDRE+ P GF F V A+D + TVSI L+DINDN PVF + Y E + + V A D D G NG V +++ E +PF+L +Y+ +DRE + S Y F + A D RKTAT +VS+V+ D ND +P+F FP + + +++LSY P V ++A D D+G NS++ F L++ FSI+ SG+L +S G L I A D GSP+ +A L I I D P + ++++ +D T II+ I++ T IC L+T IC MA ++ S+ +
Sbjct: 52 FVKDGYFAVNQDTGVVTVKAPIDRDLDAAELCNLKPAPINGSCVREFTVMYDGGRFILVRIGIADRNDHSPQWGVSRLDVSFPENVRPNTARSISPTATDPDLGRNSVTAYRMRPDSPSFRLEVATDPITGALVPKLVVQQELDREITAFYNFTLTAEDGG--GRQTSVPLTVTVLDVNDESPVFQQNAYAGSVREDASNGWTV-LTVLATDKDIGLNGNVSYRFATETPKTIRSAFDIGLYSGSIFVRDSSKLDYETDKQYEFSVVARDAGSDPKEDRASVIINVIDVNDQKPEIELYWDKAVT-VMENK-VNATVVTLMVSDKDAGQAGEFDCSITDREQYFTLTKLNTVQSR--VFYRMATKVGLDREEFAVQNPTVSCTDRGLPPLTNSLPVTVQVLDENDSPPVFVSGGGYFRKEFAEGNSPGDQVLNVTAVDRDVGENARLTYQIVWKSSETSANPF-EIDANGLIRARETLDRERNPAGFEF----SVTASDG---PHVATATVSIPLIDINDNPPVFDRQLYQFRVTE---TDSTGQHVGDLNATDADAGSNGLVRFALHPAEVGVPFQLPSEGPSIYTLHPIDREFRAS-YQFRVIAFDQ--GATDRKTATATVSVVVADVNDCDPVFQFPTPAGDSEVRLSYQEPSDFQVAEIRATDADAGANSKLTFSLKQGNLYERFSIDPDSGKLYVKKPMSRSDMGVTRLTITATDSGSPQRSAEAALKIRID-----DRPPTSLLKDAWSADMETNKLIIICIVVATGVICAILITAICLMARKQPCSAGH 821
BLAST of Protocadherin alpha-11 vs. TrEMBL
Match: A0A267F2A8 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig016480g1 PE=4 SV=1) HSP 1 Score: 335.495 bits (859), Expect = 8.730e-94 Identity = 245/796 (30.78%), Postives = 407/796 (51.13%), Query Frame = 1
Query: 214 LIKNRFFQI-ENGDNLKVSGLIDRD-DNLELCAYRN--VNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFF--ISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFA-SEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQF--EKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSI-VRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNES-NYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQAT--FIIVGIILGTFFICCGLVTGICTMAYRRWHSSNN 2556
+K+ +F + ++ + V IDRD D ELC + +N SC+ + ++ I I D ND+ PQW + + + EN + ++ P A D D N+++ Y++ P S F ++++ + P L +++ +DRE+ +++N TL A DGG + S+ L + ++DVND P+F+ + Y S+ + T+ L + ATD DI N NV+YRF+ P ++ FD+ ++ + V+ S K + +Y FS+ A D G ++ + +V +++ + N P I L + AV ++EN+ + ++T +V D D+G G+F+CSI++ + Y + +NK +S + T DRE + C D G P S +++ ++D ND+ P F ++ E N P + +TA D D G NA+L Y+I W +S N ++++N I A ++LDRE+ P GF F V A+D + TVSI L+DINDN P+F + Y E + + V A D D G NG V +++ E +PF+L +Y+ +DRE + S Y F + A D R TAT +VS+V+ D ND +P+F FP + + +++LSY P V ++A D D+G NS++ F L++ FSI+ SG+L +S G L I A D GSP+ +A L I I D P + ++++ +D T II+ I++ T IC L+T IC MA ++ S+ +
Sbjct: 52 FVKDDYFAVNQDTGVVTVKAPIDRDLDAAELCNLKPAPINGSCVREFTVMYDGGRFILVRIGIADRNDHSPQWGISRLDVSFPENVRPNTARSISPTATDPDLGRNSVTAYRMRPDSPSFRLEVATDPITGALVPKLVVQQELDREITAFYNFTLTAEDGG--GRQTSVPLTVTVLDVNDESPVFQQNAYAGSVREDASNGWTV-LTVLATDKDIGLNGNVSYRFATETPKTIRSAFDIGLYSGSIFVRDSSKLDYETDKQYEFSVVARDAGSDPKEDRASVIINVIDVNDQKPEIELYWDKAVT-VMENK-VNATVVTLMVSDKDAGQAGEFDCSIMDREQYFTLTKLNKVQSR--VFYRMATKVGLDREEFAVQNPTVSCTDRGLPPLTNSLPVTVQVLDENDSPPVFVSGGGYFRKEFAEGNSPGDQVLNVTAIDRDVGENARLTYQIVWKSSETSANPF-EIDANGLIRARETLDRERNPAGFEF----SVTASDG---PHVATATVSIPLIDINDNPPLFDRQLYQFRVTE---TDSTGQHVGDLNATDADAGSNGLVRFALHPAEVGVPFQLPSEGPSIYTLHPIDREFRAS-YQFRVIAFDQ--GATDRNTATATVSVVVADVNDCDPVFQFPTPAGDSEVRLSYQEPPDFQVAEIRATDADAGANSKLTFSLKQGNLYERFSIDPDSGKLYVKKPMSRSDMGVTRLTITATDSGSPQRSAEAALKIRID-----DRPPTSLLKDAWSADMETNKLIIICIVVATGVICAILITAICLMARKQPCSAGH 821
BLAST of Protocadherin alpha-11 vs. TrEMBL
Match: A0A1I8JAE5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 335.495 bits (859), Expect = 1.392e-93 Identity = 245/796 (30.78%), Postives = 407/796 (51.13%), Query Frame = 1
Query: 214 LIKNRFFQI-ENGDNLKVSGLIDRD-DNLELCAYRN--VNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFF--ISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFA-SEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQF--EKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSI-VRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNES-NYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQAT--FIIVGIILGTFFICCGLVTGICTMAYRRWHSSNN 2556
+K+ +F + ++ + V IDRD D ELC + +N SC+ + ++ I I D ND+ PQW + + + EN + ++ P A D D N+++ Y++ P S F ++++ + P L +++ +DRE+ +++N TL A DGG + S+ L + ++DVND P+F+ + Y S+ + T+ L + ATD DI N NV+YRF+ P ++ FD+ ++ + V+ S K + +Y FS+ A D G ++ + +V +++ + N P I L + AV ++EN+ + ++T +V D D+G G+F+CSI++ + Y + +NK +S + T DRE + C D G P S +++ ++D ND+ P F ++ E N P + +TA D D G NA+L Y+I W +S N ++++N I A ++LDRE+ P GF F V A+D + TVSI L+DINDN P+F + Y E + + V A D D G NG V +++ E +PF+L +Y+ +DRE + S Y F + A D R TAT +VS+V+ D ND +P+F FP + + +++LSY P V ++A D D+G NS++ F L++ FSI+ SG+L +S G L I A D GSP+ +A L I I D P + ++++ +D T II+ I++ T IC L+T IC MA ++ S+ +
Sbjct: 85 FVKDDYFAVNQDTGVVTVKAPIDRDLDAAELCNLKPAPINGSCVREFTVMYDGGRFILVRIGIADRNDHSPQWGISRLDVSFPENVRPNTARSISPTATDPDLGRNSVTAYRMRPDSPSFRLEVATDPITGALVPKLVVQQELDREITAFYNFTLTAEDGG--GRQTSVPLTVTVLDVNDESPVFQQNAYAGSVREDASNGWTV-LTVLATDKDIGLNGNVSYRFATETPKTIRSAFDIGLYSGSIFVRDSSKLDYETDKQYEFSVVARDAGSDPKEDRASVIINVIDVNDQKPEIELYWDKAVT-VMENK-VNATVVTLMVSDKDAGQAGEFDCSIMDREQYFTLTKLNKVQSR--VFYRMATKVGLDREEFAVQNPTVSCTDRGLPPLTNSLPVTVQVLDENDSPPVFVSGGGYFRKEFAEGNSPGDQVLNVTAIDRDVGENARLTYQIVWKSSETSANPF-EIDANGLIRARETLDRERNPAGFEF----SVTASDG---PHVATATVSIPLIDINDNPPLFDRQLYQFRVTE---TDSTGQHVGDLNATDADAGSNGLVRFALHPAEVGVPFQLPSEGPSIYTLHPIDREFRAS-YQFRVIAFDQ--GATDRNTATATVSVVVADVNDCDPVFQFPTPAGDSEVRLSYQEPPDFQVAEIRATDADAGANSKLTFSLKQGNLYERFSIDPDSGKLYVKKPMSRSDMGVTRLTITATDSGSPQRSAEAALKIRID-----DRPPTSLLKDAWSADMETNKLIIICIVVATGVICAILITAICLMARKQPCSAGH 854
BLAST of Protocadherin alpha-11 vs. TrEMBL
Match: A0A068X3A5 (Protocadherin 1 OS=Echinococcus granulosus OX=6210 GN=EgrG_000150200 PE=4 SV=1) HSP 1 Score: 325.865 bits (834), Expect = 5.586e-89 Identity = 245/818 (29.95%), Postives = 379/818 (46.33%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI------------------EPTSKYFF-------ISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLK--------------------IHATDLDINAN--VTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNA--------------VIRIIENQDIGVVILTGV-VKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSK-KNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNL------LYRK----------TATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCG 2340
Q+ EN G +I + + I +F L +N FF+ ++ +L V+G++DR+ + LC +C W L N L + I D NDN P WS + I + EN+ + F EL A D D N I YK+ PT K + S S G P L L + +DRE + W N+TLLA+DG P T +L++ +++ D ND+ P F Y + + ST+ L+ + A D D AN V Y F+ + P Q F ++ LRV + L ++ + F + A D GRP S T V++ LK+ N +PPSI + + + +RI EN + L V V D D+G G+F+C +L ++ + + K + + I L + FDRE + IFC+D G P ++S +I ++I D NDNSP FE FY T E + Q+ A D DDG A+L Y IQW ++++ ++ + + A LDRE P G+ VI D+G P RS S V + L+D+ND IP+F Q+ YN + +ED+ + + R V + A D D V Y ++ L F ++ G +++ +DRE Q S Y + A D P + +Y TAT ++S+ I+D NDN P F+ P ++ I++S+ VG ++T + AID D+G N + + + R+ +F + E SG+L + G TL I+A D G
Sbjct: 21 QVEENTEQGQIIGSIYDKISLPLDQRFQFSLPQNPFFKFDSEGSLLVAGILDREGSSGLCKEPGFPETCEWSSFLVDNGGNYISLRVHIEDVNDNAPSWSVPFVTITIPENSAPN-FTTELSSAHDPDYGVNGIKEYKLIAPPAYEDLFMLKINPFHSPTLKRRQTRDQQRRVKSTPSPIG-SPILVLLKPLDREKLPWINLTLLAMDGSPPYYTAALEIHVRVSDDNDHSPAFTFQRYVAQLPEVAPVGSTIQLRPISSSRQSDDNGVTGPLVNHLQAMDPDEGANGRVYYSFARSTPLETQKTFAIDSHTGQLRVARPLSYDDGPIAWNFQVVATDSGRPPRSSFTDVSIQLKDANNHPPSISIQSSMSYRSQEDNEEHLDVTAVRIRENVKLMKKHLATVTVNDRDTGEGGEFDC-LLRSEDAEHFSLVLKGQLPQVMIYDLFVSGTFDREADKIRSVEIFCEDKGSPRLSSSHQIRLLIEDENDNSPVFEFPFYRLTTKEAQVKGSVVGQVKASDADDGEAARLSYEIQWPKGTRPADRVLAIDRDGNLTAKIPLDRESSPFGYNLT----VICRDNGTPSRSASAGVHLALLDVNDCIPLFSQSVYNFTLVEDYSTAFQGQRFVGIVHATDCDGPEFSRVVYLLLNSYHL-FSID-REGRIFTTRSLDRE-QESVYELHVLATDRPVGIETPEERVYTSEALLLSTPYNTATATISVSIQDLNDNPPHFVHPTNTSIPIRVSFQEDVGFVLTRMVAIDPDNGKNGTVSYRIVRGNRHGVFKLGEYSGDLYIGKKMVPEQVGTHTLQIEARDHG 828
BLAST of Protocadherin alpha-11 vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 234.187 bits (596), Expect = 7.097e-63 Identity = 204/683 (29.87%), Postives = 325/683 (47.58%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIE--PTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEIN-STLDLKIHATDLDINANVTY---RFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPG------NNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVE-SNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
I++ D NDN PQ+ + + V EN + + + +P+A D D N + Y + P + F +++G K P L + +DREL +++T+ AVDGGTPS+ S L + I D NDN P FE S Y + N + S L +K + +DL N + Y + S VP ++Q + I+ VK L E +S ++F + A D G + S T V++ + +QN P++ + G ++ V I E+ +G + V D D G + C + + + + +N L T D E ++ I D G PA +++ + + + D NDNSP F + EENQP + + A D D G NA+L Y I D+S L +++ S+ ++ A LDRE + + F +V A D G P G+ TV I+++D NDN P F + Y+ S LE+ V V D D G N V S V + F + +G + S DRE + S YTF + A D +++ V V+I + D NDN P+ P+ S+++ +LS L S+V +V+A D D G N+++ + + + LF I+ + GE+ + L+ H G L +K D G P AI + I + E
Sbjct: 119 IEVQDINDNTPQFPSPVLTLSVQENAHMGATFA-IPQATDRDTERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQ----IERSTGIISVKGPLDREEISS-FKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQ-LRPAGDSSVDNKKKYFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVYSIIADSST---RGLFEIDPSSGEVRARSPLDRE-HKERYEF----RVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVL---DMDKGENAQVQLS-VEPDVGNFVVQNGTGTILSSISFDREKE-SSYTFRLKAVDGGEP---PRSSYVGVTINVLDENDNAPVVTKPSNSSFR-RLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGNPHELFYISPSDGEIKLTKELTRKHGGLHRLVVKVSDRGKPSRHAIALVHIYVNE 777 HSP 2 Score: 147.132 bits (370), Expect = 2.281e-35 Identity = 155/537 (28.86%), Postives = 244/537 (45.44%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI----EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFE--------SSFYTQSIDCNLEINSTLDL-KIHATDLDINANVTYRFSLNVPFIVQDCFDL---NPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGEL 1932
+L + I D NDN PQ+ ++S EV EN+ + L++ KA DSD PN Y I +P K I E+S GI + ++ +DRE IS ++A D G K+ + + I++ D NDN P E S +I ++ + + + L ++ D NA VT + +VPF ++ D N L+ L +E +YR I A+D G P S ++ + + + N P I P V ENQ G +L + D DSG + + SI+ + + ++ + E A L DRE K R + + D G P+ +A + I ++D NDN P+F Y +++ E P + +T D+D G NAQ++ ++ D + I++ S DREK + + F ++ A D GEP RS V+I ++D NDN PV + N SF V V A D D+G N ++ YSI F ++P+ GE+
Sbjct: 228 LLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQV-KANDSDLGPNGEIEYTIHQASDPVPKMLQI--ERST-GI---ISVKGPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDNKKKYFLQTTTPLDYERI-RDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSP-IFSPPLFEVEFAEENQP-GEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPL------DREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQLSVEPDV-----GNFVVQNGTGTILSSISFDREKE-SSYTF----RLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKP-SNSSFRRLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGNPHELFYISPSDGEI 737 HSP 3 Score: 61.6178 bits (148), Expect = 5.406e-9 Identity = 81/304 (26.64%), Postives = 119/304 (39.14%), Query Frame = 1
Query: 1435 YTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-----------LDREKYPN----GFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFI---AHDPDFGVNGDVTYSIV----RETLLPFKLNPNSGELYSYDLV----DRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNI--LFSINETSG 2262
Y + EE PN I L A D L D L K+E + + +DRE + G ++V TD + Q IE+ DINDN P F +S E N+ A F A D D NG + Y + L ++ + GE +V DRE + S Y +I A D T Y ++ + +VI D NDN P F +S+Y+ ++S PVG V VKA D D G N +I++ + + + + I ++G
Sbjct: 27 YHVREEQPPNTLIGSLAA-----------------DQGLPDSGHLYKLEVGAPYLRVDGKTGEIFTTEIPIDRETLKDCRIKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQE------NAHMGATFAIPQATDRDTERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDS-YDLTINAVDGGTPSRY---SSALLRVVITDANDNAPQF---EKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQIERSTG 300
BLAST of Protocadherin alpha-11 vs. Ensembl Cavefish
Match: pcdh1b (protocadherin 1b [Source:ZFIN;Acc:ZDB-GENE-091015-2]) HSP 1 Score: 233.032 bits (593), Expect = 2.220e-62 Identity = 199/672 (29.61%), Postives = 315/672 (46.88%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTS---KYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEIN-STLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPG------NNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDI-ILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTS---LYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDK---DSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
I+I DENDN PQ+ + + + ENT + + Y +P A D D N I+ YK+ S F + + P L + +DRE +++++ +DGGTP + S L I I D NDN P FE S Y + N + S L +K + DL N VTY F P VQ ++ I++VK S+ E +FS+ A D+G + SK VT+ +K++N PSI + G + + + E+ +G + V D D G + C + + + + + + S+ + T ++R + RI+++ D G PA +++ + + + D+NDN+P F Y EENQP + + A D D G NA+L Y I D++ L+D N + ++ + LDRE Y + F V A D G P G+ TV + ++D NDN P F Y+ S LE+ V V D D G N V S+ E F + +G + S DRE + S YTF + A D +++ V ++I + D NDN P P+ S+YK +L P+ S T V+ +D D+G+N+++ + + + LF I+ T GE+ + + H G L +K D G P
Sbjct: 131 IEIQDENDNTPQFPSPILELAIPENTYVGAHY-SIPVAMDKDAGSNGIADYKLNSGSDAMNLFSLQVADNTDEKVPQLIVLGNLDREQRDTYDLSIKVIDGGTPPRYSSALLRITITDTNDNVPKFERSHYEGEMAENTPVGQSVLQVKANDDDLGANGQVTYSFHQPSPN-VQRLLHIDHNTGIIQVKGSVDREEVPL-LKFSVQARDNGPQAKSSKAMVTITVKDRNDNAPSIRIRGFGLVAHEDGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGDVPFQLRSASASDSTSKRKYFLQTTTPLDYERIKEYRIEIVAV--DSGNPALSSTNSLKVQVTDMNDNAPVFSPSLYEVDFAEENQPGDKVLDVVATDADSGTNAELLYSIITDSATKGLFDINP-----NTGEVRVMNQLDRE-YKERYEF----HVEAADKGVPSLKGTATVVVRVLDRNDNDPKFMLNGYSFSVLENMPPLSPVGMVTVI---DADKGENAHVQLSVEPEN-GKFVIQNGTGTILSSISFDREKE-STYTFRLKAVDGGDP---PRSSYVGITINVLDENDNAPYVTKPSNSSYK----FLQPLTSPDTRVEKVDAEDIDTGLNAELVYSITGGNPHGLFRISSTDGEITLAKEFTRKHNGLHRLVVKVSDKGKP 775 HSP 2 Score: 147.132 bits (370), Expect = 2.534e-35 Identity = 151/576 (26.22%), Postives = 257/576 (44.62%), Query Frame = 1
Query: 712 IKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAI------LRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPK-NYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFT--------IAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPY--QVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP--FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
I+I D NDN P F S +I N + + + + A D D +N + LN + F L + L V +L E + Y SI +D G P S + + + + N P ++ + EN +G +L D+D G +G+ S +P N +L ++ N II + + DRE ++ + +D G A ++ A ++I + D NDN+P + E+ N + +A + D D+G NA + + D P +L ++ + + P + + Y +++A DSG P S + ++ +++ D+NDN PVF + Y + F E+ + KV +A D D G N ++ YSI+ ++ F +NPN+GE+ + +DRE + +Y F + A D L + TATV V ++ D NDN+P F+ + Y + +P S V +V ID D G N+ +Q +E E N F I +G +L+S + T +KA+D G P ++ +TI +
Sbjct: 131 IEIQDENDNTPQFPSPILELAIPENTYVGAHYSIPV-AMDKDAGSNGIADYKLNSGSDAMNLFSLQVADNTDEKVPQLIVLGNLDREQRDT-YDLSIKVIDGGTPPRYSSALLRITITDTNDNVPKFER--SHYEGEMAENTPVGQSVLQVKANDDDLGANGQVTYSFHQPSPNVQRLLHID----HNTGIIQVKGS--VDREEVPLLKFSVQARDNGPQAKSSKAMVTITVKDRNDNAPSIRIRGFGLVAHEDGIANVSEDMPVGTPVALVEVSDKDEGENAVVTCVVAGDV----PFQLRSASASDSTSKRKYFLQTTTPLDYERIKEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAPVFSPSLYEVDFAEE---NQPGDKVLDVVATDADSGTNAELLYSIITDSATKGLFDINPNTGEVRVMNQLDREYK-ERYEFHVEAADKGVPSL-KGTATVVVRVL--DRNDNDPKFML---NGYSFSVLENMPPLSPVGMVTVIDADKGENAHVQLSVEPE--NGKFVIQNGTGTILSSISFDREKESTYTFRLKAVDGGDPPRSSYVGITINV 680 HSP 3 Score: 129.413 bits (324), Expect = 8.383e-30 Identity = 136/519 (26.20%), Postives = 228/519 (43.93%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKP----------IFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNA---ILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIP-VFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV 1884
+L I I D NDNVP++ ++ E+ ENT + L++ KA D D N ++Y +P+ + N GI ++++ +DRE + ++ A D G +K+ + I + D NDN P E S D + L +++ D NA VT + +VPF ++ + + L+ L +E EYR I A+D G P S ++ + + + N P + P V ENQ G +L V D DSG + + SI+ + +N E + N++ DRE K R + + D G P+ +A + + ++D NDN P+F Y +++ E P + +T D D G NA ++ ++ + K + I++ S DREK +++ A D G+P RS ++I ++D NDN P V + + + FL+ S +V A D D G+N ++ YSI
Sbjct: 240 LLRITITDTNDNVPKFERSHYEGEMAENTPVGQSVLQV-KANDDDLGANGQVTYSFHQPSPNVQRLLHIDHNTGI---IQVKGSVDREEVPLLKFSVQARDNGPQAKSSKAMVTITVKDRNDNAPSIRIRGFGLVAHEDGIANVSEDMPVGTPVAL-VEVSDKDEGENAVVTCVVAGDVPFQLRSASASDSTSKRKYFLQTTTPLDYERI-KEYRIEIVAVDSGNPALSSTNSLKVQVTDMNDNAP-VFSPSLYEVDFAEENQP-GDKVLDVVATDADSGTNAELLYSIITDSATKGLFDINPNTGE-----VRVMNQL-DREYKERYEFHVEAADKGVPSLKGTATVVVRVLDRNDNDPKFMLNGYSFSVLENMPPLSPVGMVTVIDADKGENAHVQLSVEPENG-----KFVIQNGTGTILSSISFDREK-----ESTYTFRLKAVDGGDPPRSSYVGITINVLDENDNAPYVTKPSNSSYKFLQPLTSPDT--RVEKVDAEDIDTGLNAELVYSIT 732
BLAST of Protocadherin alpha-11 vs. Ensembl Cavefish
Match: pcdh1a (protocadherin 1a [Source:ZFIN;Acc:ZDB-GENE-091116-32]) HSP 1 Score: 233.802 bits (595), Expect = 2.828e-62 Identity = 204/683 (29.87%), Postives = 325/683 (47.58%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIE--PTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEIN-STLDLKIHATDLDINANVTY---RFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPG------NNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVE-SNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
I++ D NDN PQ+ + + V EN + + + +P+A D D N + Y + P + F +++G K P L + +DREL +++T+ AVDGGTPS+ S L + I D NDN P FE S Y + N + S L +K + +DL N + Y + S VP ++Q + I+ VK L E +S ++F + A D G + S T V++ + +QN P++ + G ++ V I E+ +G + V D D G + C + + + + +N L T D E ++ I D G PA +++ + + + D NDNSP F + EENQP + + A D D G NA+L Y I D+S L +++ S+ ++ A LDRE + + F +V A D G P G+ TV I+++D NDN P F + Y+ S LE+ V V D D G N V S V + F + +G + S DRE + S YTF + A D +++ V V+I + D NDN P+ P+ S+++ +LS L S+V +V+A D D G N+++ + + + LF I+ + GE+ + L+ H G L +K D G P AI + I + E
Sbjct: 155 IEVQDINDNTPQFPSPVLTLSVQENAHMGATFA-IPQATDRDTERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDSYDLTINAVDGGTPSRYSSALLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQ----IERSTGIISVKGPLDREEISS-FKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQ-LRPAGDSSVDNKKKYFLQTTTPLDYERIRDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSPIFSPPLFEVEFAEENQPGEKVLDVIALDADSGTNAELVYSIIADSST---RGLFEIDPSSGEVRARSPLDRE-HKERYEF----RVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVL---DMDKGENAQVQLS-VEPDVGNFVVQNGTGTILSSISFDREKE-SSYTFRLKAVDGGEP---PRSSYVGVTINVLDENDNAPVVTKPSNSSFR-RLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGNPHELFYISPSDGEIKLTKELTRKHGGLHRLVVKVSDRGKPSRHAIALVHIYVNE 813 HSP 2 Score: 147.902 bits (372), Expect = 2.189e-35 Identity = 155/537 (28.86%), Postives = 244/537 (45.44%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI----EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFE--------SSFYTQSIDCNLEINSTLDL-KIHATDLDINANVTYRFSLNVPFIVQDCFDL---NPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGEL 1932
+L + I D NDN PQ+ ++S EV EN+ + L++ KA DSD PN Y I +P K I E+S GI + ++ +DRE IS ++A D G K+ + + I++ D NDN P E S +I ++ + + + L ++ D NA VT + +VPF ++ D N L+ L +E +YR I A+D G P S ++ + + + N P I P V ENQ G +L + D DSG + + SI+ + + ++ + E A L DRE K R + + D G P+ +A + I ++D NDN P+F Y +++ E P + +T D+D G NAQ++ ++ D + I++ S DREK + + F ++ A D GEP RS V+I ++D NDN PV + N SF V V A D D+G N ++ YSI F ++P+ GE+
Sbjct: 264 LLRVVITDANDNAPQFEKSSYEAEVSENSPVGYSVLQV-KANDSDLGPNGEIEYTIHQASDPVPKMLQI--ERST-GI---ISVKGPLDREEISSFKFHVIARDKGPSPKSSTTYVSIEVTDQNDNAPAVEIRGIGLRTHSDGVANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPAGDSSVDNKKKYFLQTTTPLDYERI-RDYRVEIVAVDSGNPALSSTNSLRVQVTDTNDNSP-IFSPPLFEVEFAEENQP-GEKVLDVIALDADSGTNAELVYSIIADSSTRGLFEIDPSSGEVRARSPL------DREHKERYEFRVTAADKGVPSHRGTATVVIKVLDRNDNDPKFMLSSYSFSVLENMPPLSPVGMVTVLDMDKGENAQVQLSVEPDV-----GNFVVQNGTGTILSSISFDREKE-SSYTF----RLKAVDGGEPPRSSYVGVTINVLDENDNAPVVTKP-SNSSFRRLSPLAAPDSVVEVVEAEDIDYGSNAELVYSIAGGNPHELFYISPSDGEI 773 HSP 3 Score: 61.6178 bits (148), Expect = 6.231e-9 Identity = 81/304 (26.64%), Postives = 119/304 (39.14%), Query Frame = 1
Query: 1435 YTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-----------LDREKYPN----GFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFI---AHDPDFGVNGDVTYSIV----RETLLPFKLNPNSGELYSYDLV----DRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNI--LFSINETSG 2262
Y + EE PN I L A D L D L K+E + + +DRE + G ++V TD + Q IE+ DINDN P F +S E N+ A F A D D NG + Y + L ++ + GE +V DRE + S Y +I A D T Y ++ + +VI D NDN P F +S+Y+ ++S PVG V VKA D D G N +I++ + + + + I ++G
Sbjct: 63 YHVREEQPPNTLIGSLAA-----------------DQGLPDSGHLYKLEVGAPYLRVDGKTGEIFTTEIPIDRETLKDCRIKGKPCFLEFEVSVTDLIQNQSPRLIEGRIEVQDINDNTPQFPSPVLTLSVQE------NAHMGATFAIPQATDRDTERNGVLKYDLSAGPEASALFSLQMANDRGEKLPQLIVLGNLDRELKDS-YDLTINAVDGGTPSRY---SSALLRVVITDANDNAPQF---EKSSYEAEVSENSPVGYSVLQVKANDSDLGPNGEIEYTIHQASDPVPKMLQIERSTG 336
BLAST of Protocadherin alpha-11 vs. Ensembl Cavefish
Match: ENSAMXT00000035285.1 (pep primary_assembly:Astyanax_mexicanus-2.0:8:8923404:8955697:1 gene:ENSAMXG00000041384.1 transcript:ENSAMXT00000035285.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 219.164 bits (557), Expect = 1.554e-58 Identity = 181/626 (28.91%), Postives = 313/626 (50.00%), Query Frame = 1
Query: 229 FFQIENGDN-LKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLD--INANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSID--ALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKL---IKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISF------LEDFGSKKNSRKVAVFI-AHDPDFGVNGDVTYSI--VRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIV 2055
F++ D L V+G IDR++ E + +N L + + ++I+D ND+ P +S+ +E+ EN + +L ARD+D N++ YK+ + ++ G PFL L++ +DRE + H + L A+DGG P K+G++++++ +ID+NDN P+F Y+ + N I + + ++++ATDLD N V Y F +V ++ FDL+P + VK + F +Y++ ID A D + + + + + N P I + + I + EN G + V D DSGM+GK +CS+ E DI ++ ++ EN I SL+T DRE ++ + KD G P ++ +++ + DVNDNSP+F Y + + E N P ++ ++AHDLD NA + Y I D + + + I E+ I A++S D E ++F ++A+DSG P S + TV++ ++D NDN+PV Y +S +E+ N+ + + A+D D G NG + +S+ V + L F L+ +G++ + ET + + I +D+ N+ TATV + IV
Sbjct: 73 LFRVNRNDGVLHVNGKIDREEVCERSSSCLINLKIALENPL-----EIHYVTVEIVDINDHPPIFSEKEKRLEISENA-IAGVRFQLQGARDADSGVNSVQMYKLSQNEHFRIEVRDRGEDGKMPFLILQKSLDRETCARHKLLLTALDGGRPQKSGTMEIIVDVIDINDNAPVFTKDTYSAKLSENAPIGTKV-IQVNATDLDNGPNGEVFYIFGQDVNRNLRRVFDLDPVTGEIVVKGPID---FEQKYQYEIDIQASDKALAPLTTDKIILIQIVDVNDNAPEIEV--TSLSIAVPENSHSGTTVALISVSDVDSGMNGKVSCSVPE----DIPFSLLQSSQEN--IYSLVTKSSLDREKTSQYDITFIAKDAGHPPLSSIKTLTVFVSDVNDNSPEFSLNPYTFYVPENNVPGMSMFSVSAHDLDLDENAIISYHIWRDPAQENKHSSFLNINPETGA-IYALKSFDFES-TKSYQFY----IVASDSGTPSLSSNVTVNVFILDQNDNVPVI---LYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSDHSL-FGLDRYTGQIRTLRSF-TETDEALHKLVILVKDN-GNVSLSATATVIIKIV 668 HSP 2 Score: 140.198 bits (352), Expect = 2.696e-33 Identity = 158/582 (27.15%), Postives = 259/582 (44.50%), Query Frame = 1
Query: 712 IKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLD--INANVTYRFSLNVPFIVQDCFDLN-----PFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKV--ESNCQIIAIQSLDREKYPNGFRFVCPYQV--IATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFI--AHDPDFGVNGDVTYSIVRETLLPFK------LNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVP----VGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
++I+D+ND+ PIF I N L+ A D D +N+ Y+ S N F ++ D PF L ++KSL E A ++ + ALD GRP + + + + + N P + + ++ EN IG T V++ N + +D N + D+ + + + ++ D E K + ++ I D T I I I+DVNDN+P+ E + E + T+A ++ D+D G+N ++ + D P L++ E+ ++ SLDREK Y + IA D+G P S T+++ + D+NDN P F Y E+ N +++F AHD D N ++Y I R+ K +NP +G +Y+ D E+ S Y F I A DS T L ++ V+V++ I D NDN P+ ++P SN + +P G LVT V+A D D G N + F L+E + LF ++ +G++ T + + L I D G+ L+A + I+I E
Sbjct: 120 VEIVDINDHPPIFSEKEKRLEISENAIAGVRFQLQ-GARDADSGVNSVQMYKLSQNEHFRIE-VRDRGEDGKMPF---LILQKSLDRETCA-RHKLLLTALDGGRPQKSGTMEIIVDVIDINDNAP--VFTKDTYSAKLSENAPIG----TKVIQVNATDLDNGPNGEVFYIFGQDVNRNLRRVFDLDPVTGEIVVKGPIDFEQKYQYEIDIQASDKALAPLTTDKIILIQIVDVNDNAPEIEVTSLSIAVPENSHSGTTVALISVSDVDSGMNGKVSCSVPEDI----PFSLLQSSQENIYSLVTKSSLDREK-------TSQYDITFIAKDAGHPPLSSIKTLTVFVSDVNDNSPEFSLNPYTFYVPEN-----NVPGMSMFSVSAHDLDLDENAIISYHIWRDPAQENKHSSFLNINPETGAIYALKSFDFESTKS-YQFYIVASDSGTPSL---SSNVTVNVFILDQNDNVPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSDHSLFGLDRYTGQIRTLRSFTETDEALHKLVILVKDNGNVSLSATATVIIKIVE 669 HSP 3 Score: 60.4622 bits (145), Expect = 1.056e-8 Identity = 60/233 (25.75%), Postives = 113/233 (48.50%), Query Frame = 1
Query: 1711 VSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGE------LYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEE-KRNI--LFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
V++E++DIND+ P+F + + E+ + + + A D D GVN Y + + ++ + GE L +DRET +++ +TA D +K+ T+ + + + D NDN P+F + Y +LS P+G+ V V A D D+G N ++ +I ++ RN+ +F ++ +GE++ + K + + I+A D LT + + I+I
Sbjct: 118 VTVEIVDINDHPPIFSEKEKRLEISENAIA---GVRFQLQGARDADSGVNSVQMYKLSQNEHFRIEVR-DRGEDGKMPFLILQKSLDRET-CARHKLLLTALDGGRP---QKSGTMEIIVDVIDINDNAPVF---TKDTYSAKLSENAPIGTKVIQVNATDLDNGPNGEVFYIFGQDVNRNLRRVFDLDPVTGEIVVKGPIDFEQKYQYEIDIQASDKALAPLTTDKIILIQI 339
BLAST of Protocadherin alpha-11 vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 219.164 bits (557), Expect = 7.005e-58 Identity = 197/675 (29.19%), Postives = 325/675 (48.15%), Query Frame = 1
Query: 367 LKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAI-QSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLED---FGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQL-SYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPR 2349
++++I+ L D NDN P + I I + ENT +++ Y +P A D D N I +Y++ + F + ++ +G K P L +++ +DRE + + DGG P K+ + L + + DVNDN+P+F+ S ++ N + +++ ++HATD D+ NA + + FS + + F ++ ++ VK+ L E + + P S+ TV +++ + N PSI ++ N + + EN + I V D D+ ++GK C ++D+ + ++ L T D E + I D GKP NTSA + I I D NDN+P F + +I E N P + ++TA D D G NA + Y + D P+ ++ I+++ + LDREK + F VIA D+G + TV + + D NDN P F A YN E+ +G+ V + D D G N VT SI+ F ++P +G + DRE Q S YTF + A DS L + T+ V+I + D NDN P+F+ P+ SNY L + GS+VT V AID D+G+N+++Q+ + LF+I++T+G + ++ +G L +K D G P
Sbjct: 160 FRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINNRY-PVPSAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSV-TQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATP---SRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYT----DHDVPFRLKPVFNDQFL---LETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDA----PDGF-NIDPRSGILSVSKRLDREKQ-EKYSFT----VIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGT------VGLITVTDADAGDNAIVTLSIINGKD-NFIIDPKTGVIKPNITFDREQQ-SSYTFVVKAVDSG---LIQTTSYAKVTINVVDVNDNRPVFVIPS-SNYSYDLVPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTGNITLQEKIANADQGLHRLVVKVKDLGQPE 800 HSP 2 Score: 82.8037 bits (203), Expect = 1.908e-15 Identity = 85/333 (25.53%), Postives = 154/333 (46.25%), Query Frame = 1
Query: 361 NNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIE-NQDIGVVILTGVVKDNDSGMDGKFNCSIL--EPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKP 1350
N ++ I+I DENDN P + Q I + + EN + +++ A D+D N + Y + P + F +S L + + +DRE ++ T++A D G+ ++ + + + D NDN P F + Y + NL + T+ L I TD D N S+ +D F ++P +++ + E S Y F + A+D G S VT+++ + N P ++P +N ++ + G V+ DND+GM+ + SI+ P+ + ++KT + NI + I N D+ + +L++ KD G+P
Sbjct: 487 NTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKI-TATDADSGSNALIIYSLGPDAPDGFNIDPRSG-----ILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGL-ITVTDADAGDNAIVTLSI---INGKDNFIIDPKTGVIKPNITFDREQ-QSSYTFVVKAVDSGLIQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDLVPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRG---LFAIDKT-TGNITLQEKIANA--DQGLH---RLVVKVKDLGQP 799
BLAST of Protocadherin alpha-11 vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 199.519 bits (506), Expect = 1.726e-52 Identity = 197/710 (27.75%), Postives = 328/710 (46.20%), Query Frame = 1
Query: 286 DNLELCAYRNVNFSC---IWRGILFCGTNNL-KILEIQI--LDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPT-----SKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRF-----SLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAI-QSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV-RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIF-PNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCG 2340
D LC ++ C + G+L K++E++I D NDN P ++ + + V EN + P A D D N + Y++ P+ S + +E +N P+L +R+ +DRE + + L AVDGG+P +GS L I + D NDN P+F+ + I N + + + +++HA+D D NA V YR + F L+ + ++ V L E + YR I A D G + TVT+ + + N P+I ++ N VI I E + + + V D D G +G C I P ++ + K N ++ T + D E K + I D G + + + ++I ++D NDN+P F + Y ++ E N + ++A D D NA++ Y + D + ++ II++ + LDREK N + ++A D G P G+ TV + ++D+NDN P F A ++ E+ K+S V +A D D G NG V SI+ + F ++P SG + S DRE Q Y + A D + +++TV V I + D NDN PI + P+ + YK + +P G++VT V A+D D+ IN+++++ + + LF I+ G + L+ H G L ++ D G
Sbjct: 103 DREALCGGQDPGDECHVDVQVGVLPVQPGPFFKLIEVRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQP-ANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHV-VQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREE-SPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNP---EVPFQLKKLTYPNQYLLE--TRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPDAP-----TMFHMDPETGIISLTEQLDREKKAN-----YSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENV--PKHSTVGMVTVA-DSDEGENGRVRLSILGTDNRQLFSIDPESGMIRSNVGFDRE-QRHYYVLEVQATDGGEPV---RSSTVKVVIHVMDINDNSPIVLMPPSNTTYKFVVPRTLP-GTIVTEVSAVDNDAEINAELRYHIVGGNPHNLFHIDPVIGNITLMEPLTETHHGLHRLVVRVSDIG 786 HSP 2 Score: 109.383 bits (272), Expect = 2.228e-24 Identity = 148/586 (25.26%), Postives = 261/586 (44.54%), Query Frame = 1
Query: 700 LQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSL--NVPFIVQDCFDLN----------PFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTK---SENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFE-KEFYHYT-----IFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPN---KLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQF-ILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+++ I + D+NDN P F + T S+ N ++ A D D AN R+ L + P V F+L+ P+ L V+KSL E Y ++ A+D G P + +++ + N P + + I EN +G ++ D D+G + + + K +N ++++ N + +RE ++II D G +A +++ + DVNDNSP E ++ I E + N +A +T D D G N + I Y+P +L K+ Q + +++ + Y +V Q+ A D+G S + +V+I+L+D NDN PVF + Y +S E+ K+ V+ A D D N ++ Y + + F ++P +G + + +DRE + + Y+F+I A+D +L ATV V+++ D NDN P F + + ++ VP S V +V D D G N +++ IL + R LFSI+ SG + ++ + L ++A D G P ++ ++ I +
Sbjct: 137 IEVRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQ-PANDPDSEANGVRRYELLPSDPATVS-AFELSVTETANGEKVPY---LVVRKSLDREE-RQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSP--VFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTV--NGLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCYI------YNPEVPFQLKKLTYPNQYL-LETRETLDYETKNEYVV--QIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVS---ATDRDMDKNAEMVYFLGPDAPTMFHMDPETGIISLTEQLDREKK-ANYSFTILAKDQGIPVL-EGNATVIVNVL--DVNDNRPRFSL---AEFDFYVNENVPKHSTVGMVTVADSDEGENGRVRLSILGTDNRQ-LFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVRSSTVKVVIHV 692
BLAST of Protocadherin alpha-11 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004042.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 192.2 bits (487), Expect = 1.632e-49 Identity = 182/691 (26.34%), Postives = 309/691 (44.72%), Query Frame = 1
Query: 355 GTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGG-TPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPN--KLIKVESNC-QIIAIQSLDREKYPNGFRFVCPYQ--VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVL---------SVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
GT + +L + DENDN+P++ + V E+ + S + L A D+D N I Y++ +F ++ + +DRE + + + A+DGG TP + S L++ + DVND+ P F ++ Y + + + + A D D N RFSL+ F ++P ++ ++L+ + ++ D G P + TTVT+ ++ +P PG + E+Q G I VV S G + + N + ++ E + ++ D E + +L++ +D G P F+ ++ + ++D+NDN+P+F + + EN P TI LTA D D G+N Q+ Y S+ D N + +V N +I ++ +LDRE V Y+ V ATD G P + + V I + D NDN P F Q F + ED +V+ D D G N +T+S++ + LPF ++P++GE+ ++RE + S Y + A D T + V+IV++D NDN P F ++ Y I+ +LV V A D D G N Q+ F + + N F + SGE+ + L S + + + + A+D G P L++ +TI I
Sbjct: 8 GTGTVTVL---VEDENDNLPRFGAAELRAAVPEDAPIGS-DVALVNATDADAGLNAIISYRLRGGDGHFSVNPSTGQ------IITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAV-FAVTARDADAGPNGDLRFSLS--GSASAGFSVDPRRGVIHAARALQGP--RDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGEFP--RFAPGPRS-FSFREDQPPGTTIT--VVAARSSRRAGPVSYHLASGGNLGDVFAVDPQSGE------VSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRF-WAKVPENTPPRTIVVLTAVDKDSGINGQVDY------SIIDGNIGNVFRVNPNSGEIRSVSTLDREN-------VASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQIF-SAHVREDAAVGFPVLRVSTL---DADEGPNAAITFSLL-DPSLPFSIHPSTGEITVSRRLNREDR-SGYAVKVRASDP------AWTVSTDVTIVVDDVNDNAPRF---GQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTEN--FRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINI 641 HSP 2 Score: 144.436 bits (363), Expect = 7.339e-35 Identity = 169/684 (24.71%), Postives = 293/684 (42.84%), Query Frame = 1
Query: 367 LKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPF----IVQDCFDLNPFNAILRVKKSLKHECFAS--EYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSIL---EPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWD--TSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+K+L I + DENDN P+++Q I V F + D+DE PN I++ ++P+ + S + + R ++RE S + V + A D P+ T S + I + DVNDN P F + Y E L ++ A+D D AN F + + +D +++ LR + A+ +Y F + A+D GRP S TVT+++ N P L + G IL D D ++G+ S++ + +D+ + + L + D + + + +D G+P ++ A I + + N +P+F ++ E + ++A++TA D D G+N + Y I + L+D + + + ++ + EK N V A D G ++ + VSI + D+NDN P+ + Y E+ S V V A D D N YS+ F LN +G L + +D ET+ Y ++ A + P Y +T V + I N+ P F+ + Y +S PVG+ V V A D+D+GI+ + ++L E R+ FS+NE +GE++ S+ L + TL + A + GS R + ++ + +
Sbjct: 424 VKVL-ISVTDENDNSPRFTQ--IFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPSLPFSIHPSTGE-------ITVSRRLNREDRSGYAVKVRASD---PAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSE-GEALVARVSASDADDGANGQVFFFMRSQTENFRVGRDSGEIHSVRP-LRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLR--ERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNASRRFDV---------DAGGFLHLRASLAGD--AGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFD---ISRASGDVLLVGELDYETEKLYN-------LSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTT---VLVMDAVDADSPSNAVTMYSLDDGEADLFVLNQKTGVLTTQGFLDYETK-QTYELTVRAFNYPDTFHY---STAQVHVQITGVNEYFPRFV---QREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNV 1059 HSP 3 Score: 141.354 bits (355), Expect = 5.657e-34 Identity = 147/603 (24.38%), Postives = 263/603 (43.62%), Query Frame = 1
Query: 604 LKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNG---------FRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD-SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+ + R +D E + + + A D G P + L+L + ++D+NDN P F SS + + N + + L D IN V Y + + + F +NP + +R +L E AS Y ++ A D G P + V + + ++N P + E+ +G +L D D G + S+L+P + +++ + E + ++ +RE ++ + + D PA+ S +++I++ DVNDN+P+F + Y+ E ++ +A+++A D DDG N Q+ + ++ T N + +S +I +++ L R + P G + FV V A D G P S TV+I ++ N N P F + Y+ + + ++ A DPD VNG + YS+V + + ++G S ++ ++ ARD L R TA +SV+ + N P F P ++ L P GS + V A D D+G+N I + + + LF I+ SG++L L + L + A D G T ++I +
Sbjct: 288 VSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVVLTAVDKDSGINGQVDYSI---IDGNIGNVFRVNPNSGEIRSVSTLDRENVAS-YELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFT---QIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPS---LPFSIHPSTGE------ITVSRRLNREDRSGYAVKVRASD---PAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTE----NFRVGRDSG-EIHSVRPL-RYRDPAGGGSGANLNKYSFV----VTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVA---ATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNAS-RRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVT----EENQYAPRFAHP---PLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISV 850 HSP 4 Score: 112.079 bits (279), Expect = 5.595e-25 Identity = 124/477 (26.00%), Postives = 201/477 (42.14%), Query Frame = 1
Query: 1000 GRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIR--IIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGK-PAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSL---YDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLED--------FGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDS--PTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
G P TVT+ ++++N P A +R + E+ IG + D D+G++ + + + D ++N + + +IT DRE + L + D G P ++SA + + + DVND++P+F Y + +TA D D G N LR+ + S DP + + I A ++L G R V +D G P RS TTV++ D + P F + SF ED + ++SR+ H G GDV F ++P SGE+ + +D E Q Y + ARDS P Y K + + + D NDN P F + S + ++ P ++V L A+DKDSGIN Q+ + + + +F +N SGE+ + + L + L +KA D GSP Q T+++
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRF----GAAELRAAVPEDAPIGSDVALVNATDADAGLNAIISYRL---RGGDGHFSVNPSTGQ------IITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSASAGFSVDPRRGV-------IHAARAL------QGPRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGE-FPRFAPGPRSFSFREDQPPGTTITVVAARSSRRAGPVSYHLASGGNLGDV-----------FAVDPQSGEVSVHRALDHEYQ-HHYELVVEARDSGFPPFSAYLK-----LEVDVLDINDNAPEF---SSSRFWAKVPENTPPRTIVVLT-AVDKDSGINGQVDYSIIDGNIGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSP----TQHCTVKV 426 HSP 5 Score: 110.153 bits (274), Expect = 1.938e-24 Identity = 148/614 (24.10%), Postives = 259/614 (42.18%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPT--SKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTK--SENIAIISLITNKIFDREVKTRIQLIIFCKDFGK-PAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQ-LRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVN-GDVTYSIVRETLL---PFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNES-NYKIQLSYLVP--VGSLVTLVKAIDKD 2181
I + +EN P+++ + + + EN S + A D+D N Y I S F IS + + L +D E +N+++ A DGG +KT + I + DVNDN P+ +S Y I N +T+ L + A D D +N +SL+ D F LN +L + L +E Y ++ A ++ S V + + N Y P + N V+ E+ +G + + D D+G+DG + ++ +++K S N +I + DRE + L + K+ G F+ + + I ++ P F YH + E + ++AHD D + + IQ + + + ++ +I + S LDRE P + V+A D GEP +G+T V + L D+NDN P + ++ + G V A DPD N G T+ ++ F L+ +SG L + +DRE +P ++ + D+ + L T+TV++ + + D NDN P+E+ + ++ ++Y G + V+ D D
Sbjct: 743 ISVTEENQYAPRFAHPPLELSLPENHPAGSSLARV-TATDTDAGVNGAIVYSIASGDGSGLFDISRASGD------VLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTV-LVMDAVDADSPSNAVTMYSLD--DGEADLFVLNQKTGVLTTQGFLDYET-KQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVS--ESAPVGAPVGSVFATDRDAGIDGTV---------FYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDANDPPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNA----GRAFSINAHTGLIVVASPLDRESVP-----LYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLLTSSAKVTENQPAG-----MTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLS-SSGLLKTARPIDREQKP-EFHLPVAIADAGSPPL---TSTVTLHLSVLDQNDN------PSEARDVRVHVNYFGSPFPGGFIGDVRPRDPD 1309 HSP 6 Score: 91.6633 bits (226), Expect = 8.838e-19 Identity = 160/686 (23.32%), Postives = 278/686 (40.52%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI--EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSE----NIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKV-ESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQR--SGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL---LPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD--SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINS---QIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+ I I+ N N P++ + V + + L++ A D D N Y + S+ F + + FL LR + + S +VT+ A D G P + +I + + N P F S+ N S+L ++ ATD D N +S+ FD++ + + + L +E Y S+ A D G + + V++ + + N PP +L ++ I EN G +L D DS P N + +++ +++ N L T D E K +L + ++ ++A++ + I VN+ P+F + Y++ + E + + A D D G++ + Y + ++ +K V E +II LDRE+ + +VIA ++G + V++ + D ND PVF A Y+ E + V AHD D G T+S + ++ F +N ++G + +DRE+ P Y ++ A D P T T V + +ED NDN P + S+ K+ + P G V ++A D D N Q + + FS++ +SG L T+ + K E L + D GSP LT+ L + +
Sbjct: 637 VTINIVVPNANAPRFLRERYSTPVAATVRAGTRILDM-SAVDPDRDVNGQIAYSVVGGNASRRFDVDAGG-------FLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSL-ARVTATDTDAGVNGAIVYSI-ASGDGSGLFDISRASGDVLLVGELDYET-EKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPP--MLNASDYYPVIPENAPSGTTVLVMDAVDADS------------PSNAVTMYSLDDGEADLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESR----SKGFSVNEHTGEIIVSSQLDREREASAT-----LRVIAKNAGSIRGFDVDEVLVNVAITDANDP-PVFSSALYHGRVSE---AASVGTHVVGVSAHDFD-SPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVP-LYNLTVVAVDMGEPP-----ATGTTVVVVALEDVNDNGPFLL---TSSAKVTENQ--PAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLS-SSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSV 1271 HSP 7 Score: 89.3521 bits (220), Expect = 4.393e-18 Identity = 72/244 (29.51%), Postives = 124/244 (50.82%), Query Frame = 1
Query: 1678 SGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLED--FGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD-SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTI---EIGEF 2391
+GEP+ +G+ TV++ + D NDN+P F A + ED GS VA+ A D D G+N ++Y + R F +NP++G++ + +DRE + S Y +TA D PT L +++ ++ + + D ND+ P F+ + Y P G+ V V A D D+G N ++F L + FS++ G + + L + + TL ++ D G+P +A+ +T+ + GEF
Sbjct: 1 AGEPRLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGS-----DVALVNATDADAGLNAIISYRL-RGGDGHFSVNPSTGQIITTASLDREGRES-YVLEVTALDGGPTPGL---SSSATLVVAVTDVNDHTPRFL---NAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSA-SAGFSVDPRRGVIHAARALQG-PRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGEF 229 HSP 8 Score: 51.6026 bits (122), Expect = 1.418e-6 Identity = 82/391 (20.97%), Postives = 149/391 (38.11%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI--EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLI--KIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYR-FSLNVPFIVQD-----CFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIF------DREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLD 1500
+ +QI N+ P++ Q V E+ + + + A D D + +Y + E SK F ++ + + +DRE + + ++A + G+ ++L+ I D ND P+F S+ Y + + + + + + A D D + +R FS F++Q F +N ++ V L E Y ++ A+D G P T V + L++ N P +L + ++ ENQ G+ +L D D L P + + SL ++ + DRE K L + D G P ++ + + ++D NDN + H F P I + D D
Sbjct: 950 VHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSV-FATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGE------IIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEAASVGTHV-VGVSAHDFD--SPPGWRTFS----FLIQSGNAGRAFSINAHTGLIVVASPLDRESV-PLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLL----TSSAKVTENQPAGMTVLNLEAGDPD-----------LPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNPSEARDVRVHVNYFGSPFPGGFIGDVRPRDPD 1309
BLAST of Protocadherin alpha-11 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004043.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004043.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 191.815 bits (486), Expect = 1.930e-49 Identity = 182/691 (26.34%), Postives = 309/691 (44.72%), Query Frame = 1
Query: 355 GTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGG-TPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPN--KLIKVESNC-QIIAIQSLDREKYPNGFRFVCPYQ--VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVL---------SVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
GT + +L + DENDN+P++ + V E+ + S + L A D+D N I Y++ +F ++ + +DRE + + + A+DGG TP + S L++ + DVND+ P F ++ Y + + + + A D D N RFSL+ F ++P ++ ++L+ + ++ D G P + TTVT+ ++ +P PG + E+Q G I VV S G + + N + ++ E + ++ D E + +L++ +D G P F+ ++ + ++D+NDN+P+F + + EN P TI LTA D D G+N Q+ Y S+ D N + +V N +I ++ +LDRE V Y+ V ATD G P + + V I + D NDN P F Q F + ED +V+ D D G N +T+S++ + LPF ++P++GE+ ++RE + S Y + A D T + V+IV++D NDN P F ++ Y I+ +LV V A D D G N Q+ F + + N F + SGE+ + L S + + + + A+D G P L++ +TI I
Sbjct: 8 GTGTVTVL---VEDENDNLPRFGAAELRAAVPEDAPIGS-DVALVNATDADAGLNAIISYRLRGGDGHFSVNPSTGQ------IITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAV-FAVTARDADAGPNGDLRFSLS--GSASAGFSVDPRRGVIHAARALQGP--RDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGEFP--RFAPGPRS-FSFREDQPPGTTIT--VVAARSSRRAGPVSYHLASGGNLGDVFAVDPQSGE------VSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRF-WAKVPENTPPRTIVVLTAVDKDSGINGQVDY------SIIDGNIGNVFRVNPNSGEIRSVSTLDREN-------VASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQIF-SAHVREDAAVGFPVLRVSTL---DADEGPNAAITFSLL-DPSLPFSIHPSTGEITVSRRLNREDR-SGYAVKVRASDP------AWTVSTDVTIVVDDVNDNAPRF---GQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTEN--FRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINI 641 HSP 2 Score: 144.05 bits (362), Expect = 9.522e-35 Identity = 169/684 (24.71%), Postives = 293/684 (42.84%), Query Frame = 1
Query: 367 LKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPF----IVQDCFDLNPFNAILRVKKSLKHECFAS--EYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSIL---EPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWD--TSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+K+L I + DENDN P+++Q I V F + D+DE PN I++ ++P+ + S + + R ++RE S + V + A D P+ T S + I + DVNDN P F + Y E L ++ A+D D AN F + + +D +++ LR + A+ +Y F + A+D GRP S TVT+++ N P L + G IL D D ++G+ S++ + +D+ + + L + D + + + +D G+P ++ A I + + N +P+F ++ E + ++A++TA D D G+N + Y I + L+D + + + ++ + EK N V A D G ++ + VSI + D+NDN P+ + Y E+ S V V A D D N YS+ F LN +G L + +D ET+ Y ++ A + P Y +T V + I N+ P F+ + Y +S PVG+ V V A D+D+GI+ + ++L E R+ FS+NE +GE++ S+ L + TL + A + GS R + ++ + +
Sbjct: 424 VKVL-ISVTDENDNSPRFTQ--IFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPSLPFSIHPSTGE-------ITVSRRLNREDRSGYAVKVRASD---PAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSE-GEALVARVSASDADDGANGQVFFFMRSQTENFRVGRDSGEIHSVRP-LRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLR--ERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNASRRFDV---------DAGGFLHLRASLAGD--AGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFD---ISRASGDVLLVGELDYETEKLYN-------LSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTT---VLVMDAVDADSPSNAVTMYSLDDGEADLFVLNQKTGVLTTQGFLDYETK-QTYELTVRAFNYPDTFHY---STAQVHVQITGVNEYFPRFV---QREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNV 1059 HSP 3 Score: 141.354 bits (355), Expect = 6.916e-34 Identity = 140/566 (24.73%), Postives = 251/566 (44.35%), Query Frame = 1
Query: 604 LKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNG---------FRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD-SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELL 2271
+ + R +D E + + + A D G P + L+L + ++D+NDN P F SS + + N + + L D IN V Y + + + F +NP + +R +L E AS Y ++ A D G P + V + + ++N P + E+ +G +L D D G + S+L+P + +++ + E + ++ +RE ++ + + D PA+ S +++I++ DVNDN+P+F + Y+ E ++ +A+++A D DDG N Q+ + ++ T N + +S +I +++ L R + P G + FV V A D G P S TV+I ++ N N P F + Y+ + + ++ A DPD VNG + YS+V + + ++G S ++ ++ ARD L R TA +SV+ + N P F P ++ L P GS + V A D D+G+N I + + + LF I+ SG++L
Sbjct: 288 VSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVVLTAVDKDSGINGQVDYSI---IDGNIGNVFRVNPNSGEIRSVSTLDRENVAS-YELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFT---QIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPS---LPFSIHPSTGE------ITVSRRLNREDRSGYAVKVRASD---PAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTE----NFRVGRDSG-EIHSVRPL-RYRDPAGGGSGANLNKYSFV----VTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVA---ATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNAS-RRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVT----EENQYAPRFAHP---PLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRASGDVL 813 HSP 4 Score: 112.079 bits (279), Expect = 6.027e-25 Identity = 124/477 (26.00%), Postives = 201/477 (42.14%), Query Frame = 1
Query: 1000 GRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIR--IIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGK-PAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSL---YDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLED--------FGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDS--PTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
G P TVT+ ++++N P A +R + E+ IG + D D+G++ + + + D ++N + + +IT DRE + L + D G P ++SA + + + DVND++P+F Y + +TA D D G N LR+ + S DP + + I A ++L G R V +D G P RS TTV++ D + P F + SF ED + ++SR+ H G GDV F ++P SGE+ + +D E Q Y + ARDS P Y K + + + D NDN P F + S + ++ P ++V L A+DKDSGIN Q+ + + + +F +N SGE+ + + L + L +KA D GSP Q T+++
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRF----GAAELRAAVPEDAPIGSDVALVNATDADAGLNAIISYRL---RGGDGHFSVNPSTGQ------IITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSASAGFSVDPRRGV-------IHAARAL------QGPRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGE-FPRFAPGPRSFSFREDQPPGTTITVVAARSSRRAGPVSYHLASGGNLGDV-----------FAVDPQSGEVSVHRALDHEYQ-HHYELVVEARDSGFPPFSAYLK-----LEVDVLDINDNAPEF---SSSRFWAKVPENTPPRTIVVLT-AVDKDSGINGQVDYSIIDGNIGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSP----TQHCTVKV 426 HSP 5 Score: 110.153 bits (274), Expect = 2.214e-24 Identity = 144/596 (24.16%), Postives = 253/596 (42.45%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPT--SKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTK--SENIAIISLITNKIFDREVKTRIQLIIFCKDFGK-PAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQ-LRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVN-GDVTYSIVRETLL---PFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNES-NYKIQLSYL 2133
I + +EN P+++ + + + EN S + A D+D N Y I S F IS + + L +D E +N+++ A DGG +KT + I + DVNDN P+ +S Y I N +T+ L + A D D +N +SL+ D F LN +L + L +E Y ++ A ++ S V + + N Y P + N V+ E+ +G + + D D+G+DG + ++ +++K S N +I + DRE + L + K+ G F+ + + I ++ P F YH + E + ++AHD D + + IQ + + + ++ +I + S LDRE P + V+A D GEP +G+T V + L D+NDN P + ++ + G V A DPD N G T+ ++ F L+ +SG L + +DRE +P ++ + D+ + L T+TV++ + + D NDN P+E+ + ++ ++Y
Sbjct: 743 ISVTEENQYAPRFAHPPLELSLPENHPAGSSLARV-TATDTDAGVNGAIVYSIASGDGSGLFDISRASGD------VLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTV-LVMDAVDADSPSNAVTMYSLD--DGEADLFVLNQKTGVLTTQGFLDYET-KQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVS--ESAPVGAPVGSVFATDRDAGIDGTV---------FYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDANDPPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNA----GRAFSINAHTGLIVVASPLDRESVP-----LYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLLTSSAKVTENQPAG-----MTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLS-SSGLLKTARPIDREQKP-EFHLPVAIADAGSPPL---TSTVTLHLSVLDQNDN------PSEARDVRVHVNYF 1291 HSP 6 Score: 91.6633 bits (226), Expect = 9.933e-19 Identity = 160/686 (23.32%), Postives = 278/686 (40.52%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI--EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSE----NIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKV-ESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQR--SGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL---LPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD--SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINS---QIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+ I I+ N N P++ + V + + L++ A D D N Y + S+ F + + FL LR + + S +VT+ A D G P + +I + + N P F S+ N S+L ++ ATD D N +S+ FD++ + + + L +E Y S+ A D G + + V++ + + N PP +L ++ I EN G +L D DS P N + +++ +++ N L T D E K +L + ++ ++A++ + I VN+ P+F + Y++ + E + + A D D G++ + Y + ++ +K V E +II LDRE+ + +VIA ++G + V++ + D ND PVF A Y+ E + V AHD D G T+S + ++ F +N ++G + +DRE+ P Y ++ A D P T T V + +ED NDN P + S+ K+ + P G V ++A D D N Q + + FS++ +SG L T+ + K E L + D GSP LT+ L + +
Sbjct: 637 VTINIVVPNANAPRFLRERYSTPVAATVRAGTRILDM-SAVDPDRDVNGQIAYSVVGGNASRRFDVDAGG-------FLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSL-ARVTATDTDAGVNGAIVYSI-ASGDGSGLFDISRASGDVLLVGELDYET-EKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPP--MLNASDYYPVIPENAPSGTTVLVMDAVDADS------------PSNAVTMYSLDDGEADLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESR----SKGFSVNEHTGEIIVSSQLDREREASAT-----LRVIAKNAGSIRGFDVDEVLVNVAITDANDP-PVFSSALYHGRVSE---AASVGTHVVGVSAHDFD-SPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVP-LYNLTVVAVDMGEPP-----ATGTTVVVVALEDVNDNGPFLL---TSSAKVTENQ--PAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLS-SSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSV 1271 HSP 7 Score: 89.3521 bits (220), Expect = 4.855e-18 Identity = 72/244 (29.51%), Postives = 124/244 (50.82%), Query Frame = 1
Query: 1678 SGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLED--FGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD-SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTI---EIGEF 2391
+GEP+ +G+ TV++ + D NDN+P F A + ED GS VA+ A D D G+N ++Y + R F +NP++G++ + +DRE + S Y +TA D PT L +++ ++ + + D ND+ P F+ + Y P G+ V V A D D+G N ++F L + FS++ G + + L + + TL ++ D G+P +A+ +T+ + GEF
Sbjct: 1 AGEPRLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGS-----DVALVNATDADAGLNAIISYRL-RGGDGHFSVNPSTGQIITTASLDREGRES-YVLEVTALDGGPTPGL---SSSATLVVAVTDVNDHTPRFL---NAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSA-SAGFSVDPRRGVIHAARALQG-PRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAGEF 229 HSP 8 Score: 51.6026 bits (122), Expect = 1.441e-6 Identity = 82/391 (20.97%), Postives = 149/391 (38.11%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI--EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLI--KIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYR-FSLNVPFIVQD-----CFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIF------DREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLD 1500
+ +QI N+ P++ Q V E+ + + + A D D + +Y + E SK F ++ + + +DRE + + ++A + G+ ++L+ I D ND P+F S+ Y + + + + + + A D D + +R FS F++Q F +N ++ V L E Y ++ A+D G P T V + L++ N P +L + ++ ENQ G+ +L D D L P + + SL ++ + DRE K L + D G P ++ + + ++D NDN + H F P I + D D
Sbjct: 950 VHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSV-FATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGE------IIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEAASVGTHV-VGVSAHDFD--SPPGWRTFS----FLIQSGNAGRAFSINAHTGLIVVASPLDRESV-PLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLL----TSSAKVTENQPAGMTVLNLEAGDPD-----------LPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNPSEARDVRVHVNYFGSPFPGGFIGDVRPRDPD 1309
BLAST of Protocadherin alpha-11 vs. Ensembl Sea Lamprey
Match: si:ch211-199f5.1 (protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]) HSP 1 Score: 181.03 bits (458), Expect = 8.135e-47 Identity = 170/683 (24.89%), Postives = 308/683 (45.10%), Query Frame = 1
Query: 127 IFENLPVGSVICKLSNVIIPRPSD--TTKFKLIKNRFF---QIENGDN-LKVSGLIDRDDNLELCAYRNVNFSCIWRGILFC----GTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEIN-----STLDLKIHATDLD--INANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYR-IQWDTSLYDPNKLIKVE-SNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPV-----FQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR--ETLLPFKLNPNSGELY--SYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNE 2079
++E P G+++ +LS+ + R ++ + F+L++ F +E D + +IDR+ + C SC+ R + C G L E+++LD ND+ P ++++ + +E+ E+ L + + L ARD D N + Y ++ ++ +++ L ++ +DRE + + L A DGG P ++G+ + I ++D NDN P+F + CN+ + T+ L ++ATD+D N V Y FS V V+ F L+P L +K L HE SEY SI A D G + V +H+++ N P I ++ + + E + V D DS +G C + ++ ++ + ++TN DRE L++ D G P + + ++ ++D NDN P+F + Y ++ E N P + +TA D D N + Y ++ + + + + + S+ I A++ LD E + +QV A D G P + TVS+ ++D NDN PV + + D G V V A D D NG+++Y IV+ E L F++N GE++ + + D ++++ + RD + L +AT ++ I + D +
Sbjct: 35 LYEEQPAGTLVGRLSDDLQGRVAEHPSRHFRLMRRDDFSLVHVEEADGTVSAREVIDRE---QQCGQAP---SCVIRFDVLCTLPRGLFQLVHAEVELLDINDHAPDFARSEMHVEISESVALGT-RVPLEGARDLDVGGNALRAYHLDENERFGLALRARTDGAKYAELVVKSRLDREQEGEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSPVFAQT------SCNVTVREDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVRRLFQLDPKTGKLSLKGQLDHE-LNSEYEISIQARDMGPSSIPAHCKVLVHVEDINDNAPEIKLDFIMQSRGDTVFVSEGAAYESFVGLVTVSDIDSAENGLVACHLRGHPHFKLLPYRDD--------YVVVTNSSLDREQMADYFLVLEASDGGTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLENNSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVSTYVSINPSSGAIYALRPLDYEAMTS-----LTFQVQARDDGVPPLVTNATVSVRIVDENDNAPVVTHPPLRNGTGVVRLPRDAGL---GYLVTVVRARDSDSEANGELSYRIVQGNERNL-FRINRLGGEVFTNAASVTDAAASATRHSLVVMVRDRGSPAL---SATAAIEIRVGAHGDGD 683 HSP 2 Score: 154.836 bits (390), Expect = 1.452e-38 Identity = 166/642 (25.86%), Postives = 275/642 (42.83%), Query Frame = 1
Query: 694 GSLQLL---IKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLN----VPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDI--ILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHY----TIFEENQPNFT--IAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP------FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYK--IQLSYLVPVGSLVTLVKAIDKDSGINSQIQF-ILEEEKRNILFSINETSGELLT---STVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETE---ESFLSDQATFIIVGIILGTFFICCGLVTGICTMA 2529
G QL+ ++++D+ND+ P F S I ++ + + + L+ A DLD+ N + L+ ++ D + A L VK L E EY + A D G P T V + + + N P N +R E+ G V+LT D D G +G+ S P + ++ + ++ + L D E+ + ++ I +D G + ++ + + D+NDN+P+ + +F T+F + + +T D+D N + ++ KL+ + ++ SLDRE+ + F + A+D G P R + ++ L+D NDN P F ++ Y S LE+ V A D D NG + Y++V + +NP+SG +Y+ +D E S TF + ARD L ATVSV IV D NDN P+ P N ++L +G LVT+V+A D DS N ++ + I++ +RN LF IN GE+ T S + +L + D GSP L+A + I +G + D +ET+ S L+ A + L + +G C A
Sbjct: 115 GLFQLVHAEVELLDINDHAPDFARSEMHVEISESVALGTRVPLE-GARDLDVGGNALRAYHLDENERFGLALRARTDGAKY-AELVVKSRLDRE-QEGEYTLQLTAWDGGDPPRSGTTLVRITVLDSNDNSPVFAQTSCNVTVR--EDATPGTVLLTLNATDVDEGPNGEVVYSFSSPVDAEVRRLFQLDPKTGK------LSLKGQLDHELNSEYEISIQARDMGPSSIPAHCKVLVHVEDINDNAPEIKLDFIMQSRGDTVFVSEGAAYESFVGLVTVSDIDSAENGLVACHLRGHPHF----KLLPYRDDYVVVTNSSLDREQMADYFLVL-----EASDGGTPPRVAARQFTVRLLDENDNEPRFHRSTYEASLLEN---NSPGAYVTTVTAWDADAEHNGMIAYNVVESEVAGASVSTYVSINPSSGAIYALRPLDYEAMTS-LTFQVQARDDGVPPLV-TNATVSVRIV--DENDNAPVVTHPPLRNGTGVVRLPRDAGLGYLVTVVRARDSDSEANGELSYRIVQGNERN-LFRINRLGGEVFTNAASVTDAAASATRHSLVVMVRDRGSPALSATAAIEIRVGAHGDGDDGA-DETQPLDASMLAVMALGAACALTLAAVVLVASTKSGSCGAA 727
BLAST of Protocadherin alpha-11 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006996.1 (pep scaffold:Pmarinus_7.0:GL476780:2096:143714:1 gene:ENSPMAG00000006222.1 transcript:ENSPMAT00000006996.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 181.8 bits (460), Expect = 2.839e-46 Identity = 190/682 (27.86%), Postives = 316/682 (46.33%), Query Frame = 1
Query: 262 VSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKY--FFISSEKSNKGIKPFLKLRRGIDRELISWHNV--TLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSK--TTVTLHLKNQNLYPPSIL-LPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKN--YDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPA--FNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQ--VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL-LPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD-SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSG 2262
SGLI L+ A + + R G + I +LD NDN P + ++S V EN + + + +A D D PNN Y I PTS Y +F + G+ + L R +D E I + T++A+DGG+P ++ ++++ D NDN PIF+ + Y+ +I N+ +T+ L ++ATD D + + SL F +N + + L E S+Y + A+D G ++ TV + L + N P+ LP + I+EN G I T D D +G +I +P N Y I K ++ + + N I +++ +++ D G P SA +++++ DVNDN P F Y + E N T+ Q+TA D D+G N + Y + +L P+ + + +Q LDRE V YQ ++ATD G P S +TT+S+ ++D+NDN P F A +S +E S V D D G+N ++++ I F + G + + +DRET+ S Y+ I A D P R+T T ++ +++ D NDN P+F+ E +Y++ + V G+++ V+A D D GIN ++ + + ++ F +N +SG
Sbjct: 81 ASGLISVAAALDFEATPRFTVTVMARD--GGGQETAGRVRINLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRV-RATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGV---VTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATV-LYVNATDGDQSPEYG-QLSLIYSLEGSTQFRINARSGDITSTTLLDREAV-SQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLP---YAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAI-DPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRS---IVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMT--AALPRPDFQLDAATGLITTLVQ-LDREA-------VAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLME---SVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRTVVSLDRETKAS-YSLVIEAIDNGPAG--SRRTGTTTLDVLVLDVNDNRPLFL---EGSYEVSVPENVTRGAIILQVQATDIDEGINGRVWYRIISGNQDGNFLVNVSSG 727 HSP 2 Score: 157.918 bits (398), Expect = 5.180e-39 Identity = 184/702 (26.21%), Postives = 308/702 (43.87%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPK---ARDSDEHPN-NISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNV--TLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINA--NVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKI-----FDREVKTRIQLIIFCKDFG----------KPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYT-IFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNK---LIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVF-QQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSG--ELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAI--DCGSPRLTAIQQLTIEI 2382
I+ + ILDENDN P +SQ + E+ EN+ + L A D+D N ++Y + +S YF I ++ N + L +G+DRE I + T+L DGG + +++L + ++DVNDN P F + T + N T + + A D D+ T R+S+ D F ++ ++ + +E EY + A D P + + + L+N+ S L A + E G V++ + +IL K ++ + +S+N +I+ + +I DRE L + +D G KP A + + + D NDNSP+FE + E P + L A D D G N + R T P + +I+ ES I+ + D + + F ++++A D G P RS + +S+ ++D+NDN+P+F Y +S +E G+ VA A D D G NG VT+ I + P+ G + +DRET+ + YT + A D L + + V ++++D ND P F+ P ++ + + + VGS V VKA + G N++ + + +N F+++ TSG L+TST L K E + A+ D G P L L +E+
Sbjct: 1485 IMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNVS----MALGQGLDREGIPGGRLELTILVQDGG--RRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGG--NDTFGIDESTGLIVTVAPIDYET-RPEYLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALS--EAAVPGTVVVRVAAPQMKAPPKLPLPLAILVQKWHED-KRHKQQESDNAELIAALQGEITTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPG----AYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFIL---FRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVE-LGAPGT--LVASVWATDADAGPNGQVTFRIESGGGDKLSIGPSDGIIRVAPGANIDRETR-AAYTLMVVAVDRGNPPL---SGSAIVRVLVDDVNDERPAFLAPVQT---VSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNA-FTVHATSG-LVTSTRL---LKSYERFNLTAVATDHGRPPLWGQAGLYVEV 2152 HSP 3 Score: 154.451 bits (389), Expect = 5.917e-38 Identity = 180/667 (26.99%), Postives = 291/667 (43.63%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHP-NNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECF-ASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIIS--LITNKIFDREVKTRIQLIIFCKDFGKPAFNTS--AEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKY-PNGFRFVCPYQVIATDSGEPQR--SGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCG 2340
+ I +++ENDN P +S + V EN L + +++ A D D +SY+ + + K+ + + + +D E VT++A DGG G ++ I ++DVNDN P+F+ Y + N + + T +++ ATD D N +TY + ++ ++ + ++L +E +I ALD G P S T + + ++N P + N+ I I EN G +L D D E +I ++ + I S + + + DRE ++ LI+ D G + A ++I ++DVNDN P + Y TI E I ++A D D N L Y I Y ++ + +Q LDRE P F + V D G P R + S TV++ L D+NDN P F Y + LE G NS V A DPD G NG+VTYS+ P F+L+ +G + + +DRE + Y + A D T L ++T ++S+V+ D NDN P F + + + L V S+V + D DSG+N+++ F + ++ FS+ G + T L K +L I+AID G
Sbjct: 16 VHITLINENDNRPIFSLPLYNVSVWENATLGTSVVQV-LATDLDAGVFGQVSYHFSDDSDKFSLDPASG-------LISVAAALDFEATPRFTVTVMARDGGGQETAGRVR--INLLDVNDNTPVFQRDSYVGTAREN-DNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSP--IFDRNSYSIAIPENILAGATVLYVNATDGDQSP---------EYGQLSLIYSLEGSTQFRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAIDPPNPFY---RINAASGKIRTTGLQ-LDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLE--GLPANSTLFQV-TATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAV-AAYQLRLVATDRGTPAL---SSTTTLSLVVLDVNDNAPTF---HPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNG 646 HSP 4 Score: 143.665 bits (361), Expect = 1.327e-34 Identity = 148/578 (25.61%), Postives = 258/578 (44.64%), Query Frame = 1
Query: 694 GSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDIN--ANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDG---LNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPF-KLNPNSGELYSYDL-VDRE-------TQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFI-FPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
GS ++ I +I+ NDN+PIF Y S+ N + +++ +++ ATDLD V+Y FS + D F L+P + ++ V +L F + RF++ + +++ V ++L + N P + ++ V EN + ++ D DS + + SIL Y ++ T S +++L +++ I L I D G P N++ + + D NDNSP F++ Y I E T+ + A D D L Y ++ T I S I + LDRE +++ + + G Q++G TV+I L+D+NDN P ++ Y ++ +E+ + V+ A DPD NG + Y+I + PF ++N SG++ + L +DRE S R SP R TA+ +V+++++D NDNEP F+ P Y +Q+ +P S + V A D D G N + + + F ++ +G + T L L + A D G+P L++ L++ +
Sbjct: 12 GSARVHITLINENDNRPIFSLPLYNVSVWENATLGTSV-VQVLATDLDAGVFGQVSYHFSDD-----SDKFSLDPASGLISVAAALD---FEATPRFTVTVMARDGGGQETAGRVRINLLDVNDNTP--VFQRDSYVGTARENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFSI--TVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLEGSTQFR-----INARSG-DITSTTLLDREAVS---QYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVS---AADPDLNENGTLVYAI--DPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPR---RATASATVTVLLQDVNDNEPSFVGLP----YALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVV 555 HSP 5 Score: 135.191 bits (339), Expect = 5.290e-32 Identity = 150/590 (25.42%), Postives = 262/590 (44.41%), Query Frame = 1
Query: 676 GTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGR-PVEK--SKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSIL--EPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAI-QSLDREKYPNGFRFVCPYQVIATDSGEP-----QRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVF----IAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDL---VDRETQP-SQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGI--NSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
TP++ + +LI+I D NDN P F ++ Y + + A+D D N +++ V F ++ +L K+L E A Y + A D R P + S TV++H+ + N P L I + E Q G I T + D DSG++G+ SI+ +P+N +I ++ + + DRE + L I KD G P N++ + + ++DV+DN P F + ++ E ++++ A D ++G N + TS + + +S ++ + + LDRE+ V Y++ T P R S + + ++D NDN PVF Q Y E+ N + V A D DFGVN + YS++ + F ++ + G + S L +DRE P + +I +D R+ ATV + + + D NDN P F +++ + ++ S VG+ V +VKA+D+D G+ +++ + N F I+E++G ++T + + E L + A D P TA +L + +
Sbjct: 1149 ATPAQ-ATTSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAI-VSGNTAATFGIDNGTGVLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTP-WFLRSYEGPIDVSEGQP-GPRIATFMASDQDSGLNGELEYSIIDGDPRNEFVI----SPADGDLRVRRYVE---LDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGRNCAALLQ-HSPTSFCNGERAFYADSQTGLVYVNRPLDRER-------VAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPEN---SPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNV-SMALGQGLDREGIPGGRLELTILVQDG-----GRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPA--VGTSVIVVKAMDRDLGVCDAGTVRYSIASGG-NDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSL 1707 HSP 6 Score: 115.931 bits (289), Expect = 3.548e-26 Identity = 158/633 (24.96%), Postives = 264/633 (41.71%), Query Frame = 1
Query: 376 LEIQILDENDNVPQW-SQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKP---FLKLRRG--IDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDAL--DHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKP-AFNTSAEXXXXXXDVNDNSPQF------EKEFYHYTIFEENQPNFTIAQLT-AHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTT---------------VSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNS--------------------GELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQ 2121
L + +LD NDNVP + S + VVE + + A D+D PN ++IE S I P +++ G IDRE + + + ++AVD G P +GS + + + DVND +P F + T S+ +L + S + + AT+ N Y + + I ++ F ++ + ++ + LK S RF++ A+ DHGRP + + + + + N + P +LP N V+ I E + + I+ + D D G +G S L + + IIS T + DRE + LI+ D G+P ++ ++ + +++ D++DN P F + ++I E + P + ++ A D D G NA + Y I + NK + ++ + LDRE P Y +I S P + + T V + L DIND PVF Y D K ++ A D D G N V Y I+ ++L K + NS G L +YDL P + + A D + TATV V I+ D++ + I NE+ +++
Sbjct: 1939 LSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASV-WATDADAGPNGQVTFRIE--------SGGGDKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFV-ATVKATENYKGHNTKYTY--KIAGIGKNAFTVHATSGLVTSTRLLK-----SYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIIS--TARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFIAAGN---EGNKF-NLSRWGLLVVLSDLDREVSPY-------YAIIVKASSNPNWTPAVTTGPEFDPSKDRTLREVRVYLEDINDQWPVFTNHEYTAGVAVD---AKVGSELLQLEAVDRDVGNNSIVLYRIL--SILYIKHSSNSSTRMYNIFTLGRCARAGERDGILRTYDLF-TAYGPGYFMLEVVAADLAG---HNDTATVGVYIL----RDDQRVKIVINETPERVR 2528 HSP 7 Score: 110.923 bits (276), Expect = 1.437e-24 Identity = 184/790 (23.29%), Postives = 312/790 (39.49%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRD-DNLELCAYRNVNFSCIWRGILFC-------GTNNLKI-LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKL---RRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFD--------------LNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVE-------KSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILE------PKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQF-EKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDT----SLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEE----KRNI-LFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
+I EN P G+V+ L+ I +D F + + + G + LIDRD N+ + + ++ I G L G N + L + +LD NDN P ++ S V+EN+ + + KA D D + T +Y S GI L ID E + + ++A D P T S +L + + + D K F + Y Q+ + T+ +++ A + + L + +VQ + + + + +L E S Y ++ + D G P E K V +++ ++N P G+ ++ + E+ G ++ D D+G +G + P Y +I+ ++E+ I + F + I I D G P +T+ +S+I++DVNDN P F Y ++ E P +A + A D D G N Q+ +RI+ S+ + +I+V I DRE R V+A D G P SGS V + + D+ND P F +S LE S VA A + G N TY I F ++ SG + S L+ ++ + A D L+ + + + + D ND+ P+F+ P + ++ ++PV + V A+D D G N +++ R+ F IN TSG + T+ L + +L + A D G P
Sbjct: 1508 EIPENSPNGTVLTVLNGPIYASDAD---FGVNATLAYSLLGGSSAYF--LIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAG------TVRYSIASGGNDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAY-QAALSEAAVPGTVVVRVAAPQM----KAPPKLPLPLAILVQKWHEDKRHKQQESDNAELIAALQGEITTQAALDREATDS-YMLTVLSRDGG-PREAIAVLTNKPGAYVYVNVTDENDNSPE-FEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILII-----QNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGGDKLSIGPSDGIIRVAPGANI------DRET-----RAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLE---SLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNAFTVHATSGLVTSTRLLKSY---ERFNLTAVATDHGRPPLWGQAG---LYVEVLDVNDHRPVFVLPPNGTV-VNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRESQAVYSLILLASDQGQP 2252 HSP 8 Score: 100.908 bits (250), Expect = 1.566e-21 Identity = 195/789 (24.71%), Postives = 316/789 (40.05%), Query Frame = 1
Query: 325 SCIWRGILFCGT--NNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEP--TSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGG----TPSK--TGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKK--SLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSIL-LPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDF-GKPAF--NTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTI-----AQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLI-KVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGV--NGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL-----EEEKRNILFS------INETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIV------GIILGTFFICCGLVTGICTMAYRRWHSSNNRSPP 2568
S RGI T + I+I DENDN P + + + + E + A D DE N Y I T+ F I + G+ L + +D E+ + + LL V P++ T + + + + DVND P F S Y ID + A+D D N +S+ + ++ F ++P + LRV++ L E A Y +I A D G P S TV + + + + P L LP N ++ ++ V+ + V+ +D+ +G+ NC+ L + + + + N+ DRE +L + +D P++ S + + I+D NDNSP F + Y I EN PN T+ + A D D G+NA L Y + +S Y LI + N + Q LDRE P G ++ D G +R+ + + + ++D+NDN P F LE+ S V V A D D GV G V YSI F ++ ++G + + +D ET+P +Y + A D TA+ + + +++ D + F + Y+ LS G++V V A + + + E+KR+ I GE+ T L L + + D G PR AI LT + G + + T N+ F + AT + V G +L T++ R + R PP
Sbjct: 1139 SASTRGICLTATPAQATTSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVSGNTAATFGI---DNGTGV---LTAVKALDFEVSA--GLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRS-YEGPIDVSEGQPGPRIATFMASDQDSGLNGELEYSI-IDGDPRNEFVISPADGDLRVRRYVELDRETQAF-YNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASL-----SEAAAVLAIVSRVRASDAN-EGR-NCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEI-PENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAY---FLIDRDRGNVSMALGQGLDREGIPGGR---LELTILVQDGG--RRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLEN--SPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGNDTFGIDESTGLIVTVAPIDYETRP-EYLLMVVATDQAPPF---HTASCELRVSLQNELDEKLSFSL---AAYQAALSEAAVPGTVVVRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAELIAALQGEITTQAALDREATDSYMLTVLSRD-GGPR-EAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPP 1889 HSP 9 Score: 73.559 bits (179), Expect = 2.945e-13 Identity = 77/248 (31.05%), Postives = 117/248 (47.18%), Query Frame = 1
Query: 1699 GSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNY----KIQLSYLVPVGSLVTLVKAIDKDSGINSQIQF-ILEEEKRNILFSINETSGELLTSTVLSV----IHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPF 2415
GS V I L++ NDN P+F YN+S E+ V +A D D GV G V+Y ++ F L+P SG + +D E P ++T ++ ARD ++TA V I + D NDN P+F +Y + + L P V V+A D+DS N+QI + IL + FSI + G + + ++ I G +L I A+D GSP L + +E+ F D++P
Sbjct: 12 GSARVHITLINENDNRPIFSLPLYNVSVWEN---ATLGTSVVQVLATDLDAGVFGQVSYHFSDDS-DKFSLDPASGLISVAAALDFEATP-RFTVTVMARDGGG----QETAG-RVRINLLDVNDNTPVF---QRDSYVGTARENDNSLTP----VVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEV--FDENDNSPI 240
BLAST of Protocadherin alpha-11 vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 220.705 bits (561), Expect = 3.508e-58 Identity = 201/680 (29.56%), Postives = 330/680 (48.53%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNK-GIKP---FLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTK---SENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQ-WDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLL-PFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
+ I I DENDN P ++ S + E++ + +L A D D PN Y I IS + N + P L +R +DRE I + + + A D G+P ++ + + + ++DVNDN P FE S ++ I + ++ST+ L++ D D +N SL+ D F ++ +L K L +E A+ Y+ ++ A D G P + + V + + N N PS + P V I E+ V I T VVK N + DG P +DI+ + ++ +IS+ K DRE L++ + G + +I ++DVNDN+P F Y ++ E T+A++TA D D+G NA++ Y + DTS ++ N + + + LDRE + +V A D G+P +S +++ + D+NDN P F Q+ Y ++ E+ + N +V +A DPD G NG VTYSI+ F+++ +G + +VDRE S Y +I+A+DS + +T V+I + D NDN PIF NE++Y I V +GS V +V A D+D G N+Q+ + + + F+IN +G L ++ TL I+A D GSP +T+ ++LT+ + +
Sbjct: 776 VNISIADENDNQPTFTGPS-RFNISEDSPTGTRVGQL-TATDRDIGPNGAVTYAI--------ISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTV-LQVKVEDKDEGSNGAITLSLSGEG--SDNFTIDSTGFVLS-KTPLDYETTAA-YQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQ--VTSIPED----VAINTHVVKLNATDSDGT-------PLTFDIVEGNAGSSFKIDQSSGLISVA--KRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEVNPATGL-----VTTKRPLDREDQAS-----YSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRV---LASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITVVGVVDREALAS-YNLTISAKDSG---VPPWVSTAFVAITVADENDNSPIFA-SNETSYGIDEG--VSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTS-AFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVND 1404 HSP 2 Score: 210.305 bits (534), Expect = 6.281e-55 Identity = 211/713 (29.59%), Postives = 331/713 (46.42%), Query Frame = 1
Query: 325 SCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPN-NISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAF-YNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE-------FRNPDSTPFNETEES 2433
S R F G + + I + D NDN P ++ + V E+ + S +L A D D N +SY + + YF + S+ ++ + DRE + + V L A DGG+PS++G + I+I+DVNDN+P+F S+ YT S+D ++ I + + + + A+D D N R+S F L+ ++ V +SL E +S Y + D G P + + +++ + N PP + P R+ EN G + D DS +G I++ N D + T++ + IIS+ K D E KTR L + +D G P +A+++I I DVND+SP F Y I E T+ +TA DLD G +L YR+ + +++N I + S LDRE P+ QV A D G RS ST V+I L DINDN P+FQ + + +S S ++ A D D NGDV Y++ T + F +N ++G + +D E + +QY ++TA+D T R + TV V ++++D NDN P F +S Y + + G V V A D DSG N +I + + N+ F+++ +GE+ T L +L I A D R A + I I + F P + FN +E+S
Sbjct: 137 SYTMRISAFDGKHTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQL-TAVDLDVGINARLSYSLVSGDTSYFTVDSQG-------VIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAM-VTVTASDKDNGNNADLRYSF-TSGNTNHAFTLDAVTGVVTVSRSLDFEQRSS-YALGLSVTDRGSPPLTDTSHLLINVNDINDNPP-VFSPSAYQS-RVKENTPAGTQV---SATDRDSSTNGALVFGIIK-GNDDGVFTIDGS----TGIISIA--KSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISG----NVKGAFNIDANSGSIRVSSELDRETTPS-----YSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSE-----SSSPGHQIGQVAATDADDSSNGDVRYALSDNTDV-FSINTSTGLITLKTQLDYE-KKTQYMVTVTAKDGGT--PSRSSLTV-VKVMVDDVNDNPPQFA---KSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGP--SRFNISEDS 802 HSP 3 Score: 202.601 bits (514), Expect = 1.545e-52 Identity = 201/677 (29.69%), Postives = 314/677 (46.38%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGK--FNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQ--VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL---EEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+ + +LD NDN P++ ++ E+ E+ + S L++ K D DE N I+ S F I S F+ + +D E + + +T+ A DGG+PSK+ + Q+ I II+VNDN P F S SI ++ IN+ + +K++ATD D F + V F ++ + ++ V K L E A+ Y + A + G E T+ + + N P + PG+ A + EN IG + D D G + K + S+ + +++ N A + T + DRE + L + D GKP+ + A I++ I D+NDNSPQF + Y T+ E I ++ A D D G N ++ Y I S N + +I + +DRE + Y + A DSG P + V+I + D NDN P+F A S+ D G SR VAV A D D G N V YSIVR F +N +G L ++RET P+ YT +I A D + ++ T+ +++V+ D NDN P+F N +Y + + V V A D D G N+ +++ + +EKR F IN TSG ++T+T L K + L + A D + TA +TI +
Sbjct: 880 IHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQV-KVEDKDEGSNGAITLSLSGEGSDNFTIDSTG-------FVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHV-VKLNATDSD---GTPLTFDI-VEGNAGSSFKIDQSSGLISVAKRLDRETTAN-YTLVVRATETGSQGESVYNNATIRVLDVNDNAP-VFNPGSYAK-SLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEV----------NPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSI---ISGNHGNAFRIDSTTGRITVVGVVDREA-------LASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIF--ASNETSYGIDEGVSIGSR-VAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVLTVKKEINRETVPT-YTLTIRASDRGSPMM---TSDKELTVVVNDVNDNPPVF---NSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKR---FKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRV 1504 HSP 4 Score: 179.104 bits (453), Expect = 2.603e-45 Identity = 203/771 (26.33%), Postives = 350/771 (45.40%), Query Frame = 1
Query: 127 IFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLK-----VSGLI------DRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNK----GIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQD--CFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPY--QVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+ ENLP+G + K++ +D + + K +++ GD K +GL+ DR+D A ++ + + G + + + + I D NDN PQ+SQ+ + V ENT S L + A D D N Y I IS N + + +DRE ++ +N+T+ A D G P + + I + D NDN PIF S+ + ID + I S + + + ATD D +N +S+ + D F +N N +L VKK + E + Y +I A D G P+ S +T+ + + N PP + + + + EN +LT D+D G + SI+ N + +N T ++T D E K++ L + D + ++I +I++ND +P F ++ Y ++ E + + ++ +++A D D L Y I D +K + + I LDRE V Y QV TD+G P S T V+I+++D NDN P F + Y+ S LE+ S K+A A D D G N +TY++ R F + +SG + +DRE + S Y +I ARD T + +++++ + + D ND+ P+ N S+ + + P + V + A D D+G+N+++ F L + +F+++ T+G++ T L + TL I D G+P L+++ + I++
Sbjct: 1108 LHENLPIGQTVAKVT------ATDRDEGENAK-VTYELSVGDTSKFEVNPATGLVTTKRPLDREDQ----ASYSLRVTAMDHG--KPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRV-LASDPDAGANGRVTYSI--------ISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAV-VTATDRDEGSNAQVFYSI----VRGDTSAFAINAMNGVLTVKKEINRETVPT-YTLTIRASDRGSPMMTSDKELTVVVNDVNDNPP--VFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIIS-GNDEKRFKINSTSG------VIMTTTPLDFEEKSQYGLEVTATD---SKYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDS--FGSLSYSI---VGGKDSDKFSIDQRSGIISTADVLDRE-------LVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLA---ATDADEGTNARITYNLSRNDA--FMIGASSGVITLAQPLDRENK-STYDLAIQARDHGT---PPQASSITIRVTVIDINDHRPLI---NSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDV 1814 HSP 5 Score: 174.866 bits (442), Expect = 4.992e-44 Identity = 196/786 (24.94%), Postives = 338/786 (43.00%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPR-PSDTTKFKLI----KNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSI----------LEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQ--VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL-LPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETE 2427
QI E+ +GS + ++ + P +++LI K F N +++VS +DR+ R ++ + I + D NDN P + Q V V E++ + A D+D+ N Y + + F I++ + L+ +D E + + VT+ A DGGTPS++ + + + DVNDN P F S YT ++ NL + + ATD D AN +S+ + F ++ F + + L E AS Y +I+A D + TTV + + ++N P+ P I E+ G + D D G +G +I L+P++ IL++ T DRE L++ D G P + +A I + ++DVNDN+P+FEK + I E+ + T+ Q+ D D+G N + + + S ++S +++ LD E YQ V A D G P +S + V I ++++NDN+P F S ED + V A D D +T+ IV FK++ +SG + +DRET + YT + A ++ + ++ + +I + D NDN P+F N +Y L +P+G V V A D+D G N+++ + L + F +N +G + T L + +L + A+D G P +A+ +T+ I + N +S F++++
Sbjct: 486 QIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYS------LQVEARDGGSTSRSSSTRVTIALQDINDNSPIF-QGPYVFRVSESSS-PGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTSTG------LITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAV-CYVTATDADSGANGKISYSI-LSGNENMAFAMDRFTGEITTRVPLDRETIAS-YSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSR---FNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQLDPRSG--ILSVRST---------------LDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGS-----DNFTIDSTGFVLSKTPLDYET-------TAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTH---VVKLNATDSD---GTPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETT-ANYTLVVRATETGSQ---GESVYNNATIRVLDVNDNAPVF---NPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTS-KFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDL-NDNSPQFSQSK 1207 HSP 6 Score: 168.318 bits (425), Expect = 5.918e-42 Identity = 172/675 (25.48%), Postives = 294/675 (43.56%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSL---NVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLIT-NKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLL-PFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
++ I + DENDN P++ NS V + ENT + RDS + I+Y +K+ S + + P +D E + + + A DG K + LI + DVNDN P F S Y + ++ + S + ++ A DLD+ N +SL + + D ++R K + E AS Y+ ++ A D G P + TV + + + N P + + E+ IG ++T D D+G + S N + T++ A+ ++T ++ D E ++ L + D G P ++ + I + D+NDN P F Y + +EN P T Q++A D D N L + I + + + ++ + II+I Y N R+ Q A D G P + + V+I + D+ND+ PVF + Y+ E S V A D D G G + Y ++ + F ++ NSG + +DRET PS Y+ + ARD ++++ V+I ++D NDN PIF P Y ++S G + V A D D N +++ L + +FSIN ++G + T L K + + + A D G+P +++ + + +
Sbjct: 55 VVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQVAIVTATDRDSGTNA-AITYSLFSGENKFMMNSKTGEIRTVTP-------LDHETKDSYTMRISAFDG----KHTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIV-RQLTAVDLDVGINARLSYSLVSGDTSYFTVDS------QGVIRTKGAFDRETKAS-YQVALRAQDGGSPSRSGQATVEIEILDVNDNRP--VFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTS-GNTNHAFTLD-------AVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRV-KENTPAGT--QVSATDRDSSTNGALVFGIIKG----NDDGVFTIDGSTGIISIAK--SPDYENKTRYDLTVQ--ARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPE---STVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPS-YSLQVEARDG---GSTSRSSSTRVTIALQDINDNSPIFQGP----YVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTD--VFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMV 675 HSP 7 Score: 167.933 bits (424), Expect = 6.335e-42 Identity = 189/714 (26.47%), Postives = 317/714 (44.40%), Query Frame = 1
Query: 361 NNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFES-SFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI---LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIIS---LITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAI-QSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARD--SPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHK---GEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFI 2460
++L ++++ + D NDN PQ++++ V EN + A D+D N ISY + F + + + R +DRE I+ +++T+ A DG + + I I D NDN+P F S + S D T ++ ATD DI N +++ + + F L+P + IL V+ +L E S Y + A D G P + ++ + + + N P L G I E+ + +L V+D D G +G I L+++ S+N I S +++ D E QL + +D G P+ + +A++ I II+VNDN P F +I E+ N + +L A D D + +D + K++ + +I++ + LDRE N + V V AT++G S +I ++D+NDN PVF Y S E+ + VA A D D G N VTY + F++NP +G + + +DRE Q S Y+ +TA D P+ ++A ++++ I D NDN P F ++S Y + ++ GS + V A D D+G N ++ + + F I+ T+G + TV+ V+ + L I A D G P + + I + + N +S F E S+ D+ I
Sbjct: 666 SSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAA-GVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGE-----ITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNISEDSP---TGTRVGQLTATDRDIGPNGAVTYAI-ISGNQGNSFQLDPRSGILSVRSTLDRETIPS-YTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSG-----EIREDASVHSTVLQVKVEDKDEGSNGA------------ITLSLSGEGSDNFTIDSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDG-------TPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTAN-YTLV----VRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENL---PIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEVNPATGLVTTKRPLDREDQAS-YSLRVTAMDHGKPS-----QSAVAAITLTINDLNDNSPQF---SQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRI---TVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVAD-ENDNSPIFASNETSYGIDEGVSI 1323 HSP 8 Score: 162.54 bits (410), Expect = 3.355e-40 Identity = 179/645 (27.75%), Postives = 294/645 (45.58%), Query Frame = 1
Query: 256 LKVSGLIDRDDNLELCAYRNVNFSCIWRGIL-FCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI-EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR-ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKD 2181
+ V G++DR E A N+ S G+ + T + I + DENDN P ++ N + E + S + + A D DE N +Y I + F I++ + L +++ I+RE + + +T+ A D G+P T +L + + DVNDN P+F S Y S+ N ST L + A D D+ AN R+S+ + + F +N + ++ L E S+Y + A D +KT VT+ + N N P+ A +R EN ++ D DS G + SI+ K+ D ++ IIS T + DRE+ + + + D G P + ++I I+D NDNSP+F+ Y +I E + P+ +L A D D+G NA++ Y + + + +I S +A Q LDRE + + A D G P ++ S T+ + ++DIND+ P+ + S E+ + V +A D D G+N ++T+S++ E F L+ +G++ + +DRE Q + YT I D N A V + ++ ED DN P F P E Y + +S +P G+ + V A D D
Sbjct: 1260 ITVVGVVDR----EALASYNLTISAKDSGVPPWVST---AFVAITVADENDNSPIFASNETSYGIDEGVSIGS-RVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINA------MNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVREN-SAQSTSVLTVAADDSDVGANAVLRYSI-ISGNDEKRFKINSTSGVIMTTTPLDFEE-KSQYGLEVTATDSKY---TAKTNVTIRVINLNDITPAFTQQNYTASVR--ENSPTSTSVVKVSASDRDSF--GSLSYSIVGGKDSDKFSIDQRS-----GIIS--TADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSRNDAF-----MIGASSGVITLA-QPLDREN-----KSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVREN---QPKETHVMRILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDRE-QQAVYTLRIGVADKG-NPSLSSVADVIIDVIDED--DNCPRF-QPTE--YNVTISESLPRGASIVQVTARDID 1852 HSP 9 Score: 138.272 bits (347), Expect = 8.458e-33 Identity = 150/559 (26.83%), Postives = 241/559 (43.11%), Query Frame = 1
Query: 616 RGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAI-QSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVL 2286
R DRE S + +T+LA D G ++I + D NDN P F + Y +I N + ATD D N +SL F ++ F +N +R L HE S Y I A D TV N + S+ G + E+ +G ++ D D G++ + + S++ + S+ + + T FDRE K Q+ + +D G P+ + A + I I+DVNDN P F Y ++ E+ + +TA D D+G NA LRY + N +++ ++ + +SLD E+ R + TD G P + ++ + I + DINDN PVF + Y K+N+ A D D NG + + I++ F ++ ++G + D E + ++Y ++ ARD + Y T V+I IED ND+ P+F + SNY Q+ +GS V V A D DSG ++++ L F+I+ SG + S+ L
Sbjct: 26 RKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQV--AIVTATDRDSGTNAAITYSL---FSGENKFMMNSKTGEIRTVTPLDHETKDS-YTMRISAFDGKHTTFVPLITVDDVNDNAPFFALSVYKTG------VYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTV-----DSQGV----IRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNT----NHAFTLDAVTGVVTVSRSLDFEQ-----RSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRV------KENTPAGTQVSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGIISIAKSPDYENK-TRYDLTVQARDRGVPVKYD---TAQVTIFIEDVNDHSPVF---SPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSEL 541
BLAST of Protocadherin alpha-11 vs. Ensembl Nematostella
Match: EDO40470 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S751]) HSP 1 Score: 200.29 bits (508), Expect = 8.982e-52 Identity = 190/667 (28.49%), Postives = 311/667 (46.63%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQN-SIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI---EPTSKYFFISSEKSNKGIKPFLKLRR---GIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTV----TLHLKNQN-LYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVE-SNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGS 2343
+ + D NDN P + + S + V EN K F +L A DSD N+ Y I + + IS ++ + L + G+DRE + + + + A DGG P+ G L+L I + D NDNKP F + Y+ +I N+++ +++ L++ A+D DI N ++S+ Q F ++P ++ L +E S Y + A D G + S + + L + + N + S L G+ ++ EN IG + V D DSG +G+ N ++ Y +M + +II++ + DRE L C D G P T I + DVND +P+F++ Y ++E N +A + A D D G N++L Y I T ++ S+ I LDRE+ P V+ D G P S + +V + L D NDN P F Q+ YN S E+ + V +A DPD G N + YSI+ PF L+P G + + +D E Q S YTF + A D ++ +V + + D NDN+P+F + S+Y ++ +G + +KAID+DS + +FI+E+ + +FS+ + SG + + +L + L +KA+D G
Sbjct: 46 VYVQDLNDNSPSFVRGTSAKLVVFENDK--DFRQKL-IAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSI-LQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRS-YLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGS---YQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGY---FSMKFDVLNDESIIAV--GQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQ-----VVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFEN---SPSGSPVVQLLAQDPDIGENSLILYSILTPN-TPFFLDPRKGLVTNSRTLDHEVQ-SSYTFQVAATDGGG-----RSCNATVHVSLTDLNDNQPVF---DPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSV-DGSGLITLAKLLDRETQDNYLLTVKAVDGGG 680 HSP 2 Score: 181.415 bits (459), Expect = 5.336e-46 Identity = 205/769 (26.66%), Postives = 342/769 (44.47%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTTKFKLIK--------NRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTN--NLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEP--TSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDL-DINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGN-NAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFT-IAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRL-TAIQQLTIEI 2382
+ FEN +G IC+L + D+ KF + + + F ++ + ++ L+DR+ N+ + + G + N I+ I +LD ND P +S+ + E+++ S + A D+ N Y I T I+S + L L+ +D E I +T+ A D GTP G + I +ID+NDN P F SS SI L ++ + + + D ++ V R S ++ F+L+ L + K + + A Y + A D G P S + L + + N Y P GN + ++E I+ V D DSG +G+ + + +D + +K N I I +K+ DRE L + D G P ++SA++ +I+ DVNDN+P F++ Y + + +EN+P T + ++A D D+G N + YR +DT + + I + +I Q LDRE + + ++ATD G R T V++ + D+ND P F + Y+++ ED S + + D G N D+TY IV F LN +G L +DRE ++ + A D N + ++++ D NDN P+FI NE+ +K L P+GS+V V A+D D G N ++++ + + F INET+G + T L L + A D G + T+ Q +TI +
Sbjct: 607 EYFENTRIGQSICQLKAI----DRDSPKFAITRFIIEQGNADEVFSVDGSGLITLAKLLDRE--------TQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHV-HAISRDKGTNAEVVYSISKGNTDNIVLINSTGT-------LYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSS----SILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVF---GNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYA------FDSKVDTSKFGLRNGGKI-FIKSKL-DREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFV-KENEPVATYLGAVSASDSDEGSNGHVTYR--FDTQVA---QFIVDKQTGKITTSQVLDREA-----KASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDL--PVGSSLLTLIATDDDQQGPNSDITYMIVAGPKA-FSLNQVTGVLTLVSPLDREVT-HRHILHVVASDKGGNQSLETITYIEINVL--DVNDNYPVFI--NETTFKTVPEKL-PIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYV 1320 HSP 3 Score: 175.252 bits (443), Expect = 4.255e-44 Identity = 192/668 (28.74%), Postives = 309/668 (46.26%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLD--INANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTR-IQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRI--QWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFI----AHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVG-SLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVL--SVIHKGEETLFIKAIDCGS 2343
+ + + D NDN P + +S +E ENT++ +L KA D D I+ + IE + S + S + L + +DRE + +T+ AVDGG + I ++DVND PIF + Y +I + + S + +HA D NA V Y S D L L ++ + HE S Y ++ A D G P VT+ + + N P ++ ++R+ E+ IG T V D DSG+ G+ + S+L N + ++ N +SL K+ D R L + +D G P +++A + + ++DVND SP F Y + E P+ I ++ A D+D G N ++ Y + DTS + + + +I LDRE +VIA D G P+RS S V + + D+NDN P FQQA Y +F K + VA ++ A D D G NG VTY + + F ++ +G++ + ++DRE + S Y FSI A D ++ KT V++++ D ND P F +++ Y + ++ +PVG SL+TL+ D G NS I +++ + FS+N+ +G L + L V H+ L + A D G
Sbjct: 585 VHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQL-KAIDRDSPKFAITRFIIEQGNADEVFSVDGSG-----LITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIG-HVHAISRDKGTNAEVVYSISKG----NTDNIVLINSTGTLYLQSEVDHEKIPSLY-LTVQAKDKGTPPLFGYANVTIAVIDINDNSPQ--FNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLL--SNPGTLFNLDS----NTGALSL--TKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKF------GLRNGGKIFIKSKLDREDIEE-----YNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASY--AFF-----VKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQ-VAQFIVDKQTGKITTSQVLDREAKAS-YVFSIVATDGGSSPRVDKT---QVTVIVRDVNDCSPKF---SKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPK--AFSLNQVTGVLTLVSPLDREVTHR--HILHVVASDKGG 1200 HSP 4 Score: 170.244 bits (430), Expect = 1.799e-42 Identity = 201/680 (29.56%), Postives = 319/680 (46.91%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNN-ISYY---KIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLD--INANVTYRFSLNVP-FIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDS-GMDGKFNCSILE-PKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKD-FGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIA-IQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGS-TTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRET-LLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLV---PVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQ 2364
+LE++++D ND P + S V+E T DS +E+ A D D N ISY K++ TSK+ G K F+K + +DRE I +N+ ++A+D GTP ++ S + + + DVNDN P F+ + Y + N + + L + A+D D N +VTYRF V FIV + + L E AS Y FSI A D G KT VT+ +++ N P N + + E+ +G +LT + D+D G + I+ PK + + ++ +++L++ DREV R L + D G + T I I ++DVNDN P F E T+ E+ +A + A D D G N ++RY+I + + K+ +I+ +++LD E R+V +V ATD G+ Q+ S V+I + D NDN P F + E+ N V AHD D G+N + Y+I ++ FK+N +G + + +DRE + S+Y+ + A D R T ++ I+I+D NDN P F+ N L+Y++ P VT + A+D D+G +++ + FS++ +G L L + TL I A D GSP LT+ Q
Sbjct: 897 MLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEV-VATDVDSGENGRISYAFDSKVD-TSKFGL------RNGGKIFIKSK--LDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLG-AVSASDSDEGSNGHVTYRFDTQVAQFIVDKQ------TGKITTSQVLDREAKAS-YVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPK--FSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKAFSL--------NQVTGVLTLVSP--LDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNT----DGTFKINETTGVISTLRALDFEVTN---RYVL--RVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTN---VTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETGLIQTTHPIDRE-EISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRN-------LTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTG-KFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQ 1525 HSP 5 Score: 160.614 bits (405), Expect = 1.600e-39 Identity = 181/667 (27.14%), Postives = 303/667 (45.43%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHP-NNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGID-RELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDG----KFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDD-GLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTT-VSIELMDINDNIPVF--QQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR-ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYL-VPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAID 2334
+ I ++D NDN PQ++ +SI++ + E+T + + + D+D +S+ + F + SN G L L + ID + + + A DGG+P ++ + L +K++DVND P+F + YT + +S + +++ ATD+D N ++Y F V F L I +K L E EY + A+DHG P S V + + + N P ++ EN+ + + D+D G +G +F+ + + ++K + + T+++ DRE K I D G ++++I+ DVND SP+F K Y T+ E+ ++ L A D D G N+ + Y I + N++ V + + LDRE R + V+A+D G Q + T + I ++D+NDN PVF + F + GS VA +A D D G NG V Y IV T FK+N +G + + +D E ++Y ++A D +KT+ V+I +ED NDN P F + N I Y VP+ + VT +KA D DSG+NS+I + ++ + F IN +G + T+ + E +L ++A D
Sbjct: 793 VTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTV-SVFDADSGVLGRVSFSLLSNPGTLFNL---DSNTGA---LSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNI-IEVVATDVDSGENGRISYAFDSKVD---TSKFGLRNGGKIF-IKSKLDREDI-EEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVK--ENEPVATYLGAVSASDSDEGSNGHVTYRFDTQVAQ-------FIVDKQTGK------ITTSQVLDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKAFSLNQVTGV-----LTLVSPLDREVT---HRHIL--HVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSV-----VAAVLAVDSDQGDNGKVRYKIVNGNTDGTFKINETTGVISTLRALDFEVT-NRYVLRVSATD--MGKKQQKTSYQLVTIYVEDANDNRPTF----DKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATD 1409 HSP 6 Score: 143.665 bits (361), Expect = 2.381e-34 Identity = 174/682 (25.51%), Postives = 291/682 (42.67%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIV---IEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQD---CFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITN-KIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAH----DPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEE-TLFIKAIDCGSPRLTAIQQLTIEI 2382
I+ I++LD NDN P + + +V EN + + + D+D N +E YF + + N + + + + +DRE + + +D G P +T I + DVND P F+ Y + N +N TL ++A D D +N +++ + F ++P + ++ L E + ++ D G P +V ++L + N P NA + EN G ++ + +D D G + SIL P N L K L+TN + D EV++ + D G + N A + + + D+NDN P F+ Y FE + +I QL A D D A R+ I+ + +++ V+ + I + LDRE N V A D G V+I ++D+ND P+F +A YN + E +S+ ++V I H D G N +V YSI + L ++G LY VD E PS Y ++ A+D T L+ +V+I + D NDN P F N S+ ++L P+G V D DSG+ ++ F L LF+++ +G L + ++ + TL ++A D GSP ++ L +++
Sbjct: 264 IVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARV-SVSDADSGKNGEVNVTLEGGDGYFSMKFDVLND--ESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVN-TLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIP-QVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNA--SLFENSPSGSPVVQLLAQDPDIGENSLILYSILTP-NTPFFLDPRK---------GLVTNSRTLDHEVQSSYTFQVAATDGGGRSCN--ATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNA----DEVFSVDGSGLITLAKLLDRETQDNYL-----LTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQE------HSQALSV-IGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTGTLYLQSEVDHEKIPSLY-LTVQAKDKGTPPLF---GYANVTIAVIDINDNSPQF---NSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNP-GTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKV 902 HSP 7 Score: 137.117 bits (344), Expect = 2.492e-32 Identity = 167/691 (24.17%), Postives = 297/691 (42.98%), Query Frame = 1
Query: 286 DNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENT-KLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFE-------------SSFYTQSIDCNLEINSTLD-------------LKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMD-GKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQ-SLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYN-ISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSYDLVDRE-TQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSG 2262
D L+ + +N + + N IL+I ++D NDN P + ++++ ++ E+T ++ A D D N Y I T + + S G KL +DRE + ++ + D G P K+ + Q+ + + D+NDN P+F+ + T + + + S L L++ ATD D +N ++S + Q + ++ ++ ++++ S + + A+D G P +++ V + + + P LP + ++ EN +G +LT V DN +G+ G+ + +I E NY I + +IS+ NK D E K R L++ D P+ + I + DVND P F + Y E + ++A D D G N ++ + IQ D ++ +I Q +LD E V ATD G P +V+I ++D+NDN PVF+ N + LE+ NSR + A D D G N ++++++ T F ++ SG L + D E T QY+ +I A D+ L ++ +++ + + D ++ +P F N +YK + +G V V A D+DSG ++ F+ N L +N T+G
Sbjct: 2023 DALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIW-TGNEAGVFTIDSTTGEITTAKL---LDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIITRE----PKFELP--SYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNI-ENSNYFRI-------GQRSGVISV--NKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSG----DDKGSFAIDRKTGVIRTQRALDHETIKTHH-----VSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENL--PLNSRLYEIN-ATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPL---SSNITIIVNVADEDEYDPSF---NRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGRVFFVFYNPTSNAL-KMNATTG 2674 HSP 8 Score: 121.324 bits (303), Expect = 1.640e-27 Identity = 161/606 (26.57%), Postives = 262/606 (43.23%), Query Frame = 1
Query: 622 IDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDL-------NPFNAILRVKKS---LKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKP-AFNTSAEXXXXXXDVNDNSPQFEKEFY---HYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAI-QSLDREKYPNGF-RFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV-----RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTI 2376
+DRE +S +N+T+ V+ TP K S +L+ + D+NDN P F T + E + K+ A D D +N T +++ V V + F L A L V S + E S Y +I A D G P +++ +++ N P + I EN D+G IL D D G + + SI + I ++ T ++ N D E K +++ +D G ++SA + I ++DVNDN+P + Y + E +A+++ D D G N ++ ++ + + V ++ IIA+ QSLDRE + + F + VC D G+P R+ + I + D+ND P F + Y E+ + VA+ A D DFG N ++ Y+I R L F ++P+SG + + +DRE P Q ++ D + L + SV + + D NDN+P F N+S+Y L P GS V + A D D G NS I + + N F ++ G + S L + T + A D G A +++
Sbjct: 20 LDREKVSAYNLTI--VEFSTPPK--SYTVLVYVQDLNDNSPSFVRG--TSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTI-VSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDS-YVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIP--ENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTG------VIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYF--SMKFDVLNDESIIAVGQSLDRETHDHFFLKAVC------IDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWEN---ATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIP-QVVLTVLVHDRGSPPL---SDNCSVIVNLTDSNDNDPYF---NQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTP--NTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSL 589 HSP 9 Score: 119.013 bits (297), Expect = 8.678e-27 Identity = 159/608 (26.15%), Postives = 262/608 (43.09%), Query Frame = 1
Query: 364 NLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDE-HPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQ-DCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDF--GVNGDVTYSI--VRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKA 2169
N L+I I D NDN P++ ++ V+E+ + F + A D D N+ Y + P + F + + LKL +D E + + + + A D G+P T + ++DVNDN P F + ++ N +++ +K+ A D D +N +S +P V+ D F ++ + ++ L E Y ++ A P S T+V +++ ++N PP + P +++ EN +I T V+D D G + K SI+ N D T+ ++ E L T DRE K QL + KD P + A I+I I D NDN P F++ Y TI E P +I LTA D D G N + Y + DT + ++S I+ + + F C IA D G+ + V I++ D N++ P F + Y + F + S V + A D D NG VTY + + + F + N+G + + Q ++ I A D + L V IVI + D+ P F+ N++ ++ + VGS +T V+A
Sbjct: 1420 NTATLKIIIQDLNDNAPKFVSRNLTY-VMEDEPFN-FQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKTG------VLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSV-VKVTAYDRDSGSNAELTYS--IPSGVEMDKFSIDKHSGLIVTNSILDREK-KDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISP--VVTLKVPENSP-ARLIYTLTVQDLDYGNNTKVLYSIMS-GNTDGAFTIGRSTGE------LSTTTKLDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTY-----GVYSIDSRTGIVYSAARFETSIKQEYNFFC----IAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHI---FPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQ-GRHALYIIAEDHGSPPLRGYGI---VQIVIGNIQDDPPRFL--NQTPARVSIPENSKVGSYITTVRA 1987 HSP 10 Score: 110.923 bits (276), Expect = 2.112e-24 Identity = 174/756 (23.02%), Postives = 311/756 (41.14%), Query Frame = 1
Query: 265 SGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKA-RDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQ-SIDCNLEINSTLD-LKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKS--LKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVK----DNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFE---------------------------KEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRY------------RIQWDTSLYDPNKLIKVESNCQIIAI--QSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+G++ E + NF CI + + + I+I D+N++ PQ+++ + + NT + + D+D+ N Y+++ + + +SN G ++ G H + ++A D G+P G + I I ++ D+ P F + + SI N ++ S + ++ A+ +A VTY + F ++PF ++ V + L +E +R + A G + +++ ++N P+ +N + ++ E D G VVK D DSG +GK SI N + T++ T E + T K+ DRE L+I D G P +T+ ++ +++ D+NDN P F+ + Y + + P I +++A D D G NAQ++Y +I DT + + I V I I Q++D+ P R + ++I T EP+ EL +P + A S L + +V A P G ++Y+I E F++ SG + +D ET+ ++ ++A D + K V V I + D ND +P+F +S Y Q S +PVG++V V A DKDSG N ++ F ++ F+I+ +G + T L + ++A D GSP + +TI +
Sbjct: 1803 TGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVVESNTG---SVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASS---DAQVTYSI---ISGNKGRAFYVDPFTGVISVASADALDYES-TKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPA--FHPSNMLAQLAE--DTGAFKPRFVVKVTATDVDSGTNGKVTYSIWT-GNEAGVFTIDSTTGE------ITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQ--RALVYVRIIITR--EPK--------FELPSYFGKVP--ENAMMGTSVL--------TVRVTDNAAGLP----LGRISYNI--ENSNYFRIGQRSGVISVNKPLDYETK-RRFLLVVSAID---DTAPSKPVRVPVYINVSDVNDEKPVF---GQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRV 2502 HSP 11 Score: 94.3597 bits (233), Expect = 2.765e-19 Identity = 175/703 (24.89%), Postives = 290/703 (41.25%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQW-SQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKG----IKPFLKL-----RRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFE-SSFYTQSIDCNLEINSTLDLKIHATDLD--INANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNC--------SILE--------PKNYDIILTMNKTKSENIAI-ISLITNKIFDR---EVKTR---IQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLN-AQLRYRIQWDTSLYDPNKLIKVESNCQIIAI-QSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR-ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKG--EETLFIKAIDCGSPRLTA 2358
I++I I + D+ P++ +Q + + EN+K+ S Y+ +AR S + ++Y I NKG + PF + +D E + L+A G S G + L I +ID NDN P F S+ Q + +K+ ATD+D N VTY V F ++ + K L E AS + I D G P + + V + + + N PP + P + IR E+ G V+ + V D D +N +IL N I + T S+ I I T I R +V+ R IQ+ + D G P + + + P+FE Y + E ++ + D GL ++ Y I+ + ++ +I++ + LD Y RF+ V A D P + V I + D+ND PVF Q+ Y + E V+ A D D G NG V ++I + F ++ +G + + +D ET + + S+ A D + ++ VSV+I + D NDN P+F P ++ +Q+ +P+ S + + A D+DSG N+++ F + LF I++ SG L T+ + + +L IKA D G+P L++
Sbjct: 1947 IVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGS-YITTVRARASSDA--QVTYSII------------SGNKGRAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGV---FTIDSTTGEITTAKLLDRETTAS-FDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPP-LFDPLSEVNIR--EDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPP----QRALVYVRIIITREPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIE-------NSNYFRIGQRSGVISVNKPLD---YETKRRFLL--VVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVS---AADKDSGANGRVWFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHH-VSVRATDEGSPPMHTD---VSVTIRVLDLNDNPPVFRVPGPND--VQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSS 2602 HSP 12 Score: 93.9745 bits (232), Expect = 3.060e-19 Identity = 149/583 (25.56%), Postives = 227/583 (38.94%), Query Frame = 1
Query: 622 IDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTA--HDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVF-QQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR-ETLLPFKLNPNSG--ELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV--GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
+DRE + +T+ A P + S + I ++D NDN P F S T + N L + DLD N +S+ + F + L L E AS Y+ S+ A D P + +T+ +++QN PP ++ I E G IL D DSG +G L Y + ++T + + F+ +K KD G+ + I I D N+++PQF K Y IF + + +TA D D N ++ YR+ + L VESN + S P G + +IA D G P G V I + +I D+ P F Q +S E+ SK S V D VTYSI+ F ++P +G + S D +D E S F + +P + + + I + D NDN P F + SN QL+ V V A D DSG N ++ + + +F+I+ T+GE+ T+ +L L I+ D G P
Sbjct: 1604 LDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENSPARLIYTLTVQ--DLDYGNNTKVLYSI-MSGNTDGAFTIGRSTGELSTTTKLDRETKAS-YQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTIS--ELTPPGTSILNLTASDKDSGSNGNI-VYTLSNDTYGVYSIDSRTGI-------VYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLD---DSKNSTSLFVVESNTGSVRT-SAGFSNPPQGRHALY---IIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPEN--SKVGSYITTVRARASSD----AQVTYSIISGNKGRAFYVDPFTGVISVASADALDYE---STKNFRLHLVATPQGWVSLNGYMI-LDINVIDRNDNSPAF---HPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIP 2152
BLAST of Protocadherin alpha-11 vs. Ensembl Nematostella
Match: EDO34815 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN97]) HSP 1 Score: 191.815 bits (486), Expect = 3.435e-50 Identity = 199/726 (27.41%), Postives = 331/726 (45.59%), Query Frame = 1
Query: 265 SGLIDRDDNLE---LCAYRNVNFSCIWRGI-LFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKY--FFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTP-SKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDL--KIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVK----KSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGK--FNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAI-QSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQP----SQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
+G+I NLE +Y N+ G+ F T + I+ + D NDN P ++ + V EN+ + + L++ A D+D N Y + + F ++ SN G +++ +DRE+ ++N+T+ A DGG P S+T L++I+D NDN P F + YT SI N + + I ATD DI +N R+ LN +Q F +NP ++ + SL HE + Y F + A D +S V +H+ + N P + + I E IG + D DSG++G+ F+ + ++I +S+ + +S DRE K L + D +++ + DVNDN+P+F K ++ + E I TA D D G NA + Y + + + SN + I + LDRE + + V A D G + + V++E+ D NDN P F Y ++ V A D D G NG VTY+I+ +LPF + P++G + + +DRE Q Y +++ D + + + T+ ++I + D NDN+P F N+S Y + +PVG+ VT+V A D+DSGINSQI + L + +FSI ++G++ ++ K + I A D G+P L++ ++ + +
Sbjct: 63 TGMIKTARNLERQQTFSY-NLTIGAADHGLPSFSATTRVSIV---VGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDV-TATDADSGQNAYVTYSVTAGDSHGLFRAVTKVSNHGT---IEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVPKFSHARYTGSIQENSGPGVPVQMASSIMATDRDIESNADVRYRLNGSDSIQ--FAVNPRTGVITTRVSPPPSLDHER-TTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTIS--EAASIGQSVARVTANDPDSGLNGRIFFSINSGSEGKFEI------GRSDGVVRVS----GSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSMSY--------PGFAINSNTGSVTITRPLDRET-----KQAYSFTVHARDGGGLESN--VAVNVEIGDENDNSPQFPTVQYQTDVID---RTPVGTIVLAVNAEDRDVGNNGHVTYAIL---ILPFIIVPDTGNINTSSKLDREQQSLYTLVHYVLNLSVTD---HGVTQFTSFALLNISVTDFNDNQPQF---NQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMYSL--TGGDGVFSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHV 736 HSP 2 Score: 161.384 bits (407), Expect = 1.999e-40 Identity = 186/757 (24.57%), Postives = 315/757 (41.61%), Query Frame = 1
Query: 127 IFENLPVGSVICKLS--------NVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENT------KLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVI---ATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYL-VPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGS 2343
+FEN PVG+ + ++ N + + ++ N ++V+G +DR E+ + N+ + G+ T + I ++ILD NDNVP++S + EN+ ++ S + A D D N Y++ + F + ++ I + +D E + + ++A D +++I ++D NDN P F S +I I ++ ++ A D D N FS+N + F++ + ++RV SL E A Y ++ A+D + TVT+ L++ N P P N + + E +G VI+ D D G + S+ P +N S+ + DRE K + +D G ++ +++ I D NDNSPQF Y + + + + A D D G N + Y I L P I V I LDRE+ + + V+ TD G Q + ++I + D NDN P F Q+ Y+ + LE+ KV + A D D G+N + YS+ + F + P++G++ ++RE + Y +ITA D T +L ++ V + + D NDN P+F Y+ +S G V V A D D N + + + +F+INET+G + T VL+ K TL + A D G+
Sbjct: 123 VFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKVSNHGTIEVAGNLDR----EVNDFYNLTITATDGGVPISRTA-IAIALVRILDRNDNVPKFSHARYTGSIQENSGPGVPVQMASSIM----ATDRDIESNADVRYRLNGSDSIQFAVNPRTGV-ITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSV-ARVTANDPDSGLNGRIFFSINSG--SEGKFEIGRSDGVVRVSGSLDREAKAV-YVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFN--VDVSEGVAVGSVIVNATATDPDQGSNAAITYSMSYPG-----FAINSNTG------SVTITRPLDRETKQAYSFTVHARDGG--GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAI-----LILP--FIIVPDTGNINTSSKLDREQQS---LYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENM---PVGTKVTMVTARDEDSGINSQIMYSLTGGDGV-FSIEPSTGQIRLQKAINREAK-ENYHVTITASDRGTPVL---SSDAKVHVHVLDVNDNPPVFT---SRVYERTMSEGNAAAGEFVVQVNATDADVERNGHVTYTIMHGALG-MFTINETTGVIRTQGVLNRESKDFYTLIVMARDQGA 828 HSP 3 Score: 159.458 bits (402), Expect = 8.721e-40 Identity = 187/711 (26.30%), Postives = 305/711 (42.90%), Query Frame = 1
Query: 412 PQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI------EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASE-------YRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQD----IGVVILTGVVKDNDS-GMDGKFNCSILEP-----KNYDIILTMNKTKSENIAI---ISLITNKI-----FDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNIL-FSINETSGELLTSTVLSVIHKGEETLF-----IKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEES 2433
P ++ S E + + KA DSD+ N Y I +P S F + N G+ +K R ++R+ +N+T+ A D G PS + + ++ I + D+NDN P+F + Y+ ++ N + ++L L + ATD D N +S+ D L F A+ +V E + Y +I A D G P+ ++ + A++RI++ D TG +++N G+ + SI+ N D+ +N + S A+ +IT ++ D E T + D + AE+ I ++D NDN+P+F TI E ++A++TA+D D GLN ++ + I + K S+ + SLDRE + V V A D R G TV++ L D+NDN P F + +N+ E G S V A DPD G N +TYS+ + F +N N+G + +DRET+ + Y+F++ ARD + V+V++ I D NDN P F Y+ + PVG++V V A D+D G N + + + IL F I +G + TS+ L + TL + D G + T+ L I + +F N + FN++E S
Sbjct: 1 PVFTPASYNATFTEGSSTRGVLIATVKATDSDDGANGDVDYSIVDGNVGDPRSNSDF--TLDPNTGM---IKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSL-LDVTATDADSGQNAYVTYSV----TAGDSHGL--FRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAI--------------------ALVRILDRNDNVPKFSHARYTGSIQENSGPGVPVQMASSIMATDRDIESNADVRYRLNGSDSIQFAVNPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSGSE----GKFEIGRSDGVVRVSGSLDREA-----KAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSE--GVAVGSVIVNA-TATDPDQGSNAAITYSM---SYPGFAINSNTGSVTITRPLDRETKQA-YSFTVHARDGG-----GLESNVAVNVEIGDENDNSPQFP---TVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIL-----ILPFIIVPDTGNINTSSKLDREQQSLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDF-NDNQPQFNQSEYS 649 HSP 4 Score: 152.525 bits (384), Expect = 1.403e-37 Identity = 155/599 (25.88%), Postives = 258/599 (43.07%), Query Frame = 1
Query: 313 NVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFC-----KDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVE-SNCQIIAIQSLDREKYPNGFRFVCPYQV--IATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPI 2085
N F I G +L + I +LD NDN P++ +SI + E + + A D D N ++ I S+ F +++ +DRE + + + + A+DG + G + + + DVNDN P F + + + + S + + ATD D +N +S++ P F +N + + + L E Y F++ A D G +S V + + ++N P P +I+ +G ++L +D D G +G +IL I+ + + NI T+ DRE ++ L+ + D G F + A ++I + D NDN PQF + Y T+ E + +TA D D G+N+Q+ Y SL + + +E S QI ++++RE N Y V A+D G P S V + ++D+NDN PVF Y + E G+ V A D D NG VTY+I+ L F +N +G + + +++RE++ YT + ARD + Y T+ V ++ D NDN PI
Sbjct: 299 NYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARV-TANDPDSGLNGRIFFSINSGSEGKFEIGRSDG-----VVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVI-VNATATDPDQGSNAAITYSMSYP-----GFAINSNTGSVTITRPLDRET-KQAYSFTVHARDGGG--LESNVAVNVEIGDENDNSPQ--FPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIL------ILPFIIVPDTGNIN-----TSSKLDREQQSLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMY------SLTGGDGVFSIEPSTGQIRLQKAINREAKEN-------YHVTITASDRGTPVLSSDAKVHVHVLDVNDNPPVFTSRVYERTMSE--GNAAAGEFVVQVNATDADVERNGHVTYTIMHGALGMFTINETTGVIRTQGVLNRESK-DFYTLIVMARDQGA-VPYMDFGTIDVHVI--DKNDNTPI 850 HSP 5 Score: 83.1889 bits (204), Expect = 4.248e-16 Identity = 70/283 (24.73%), Postives = 127/283 (44.88%), Query Frame = 1
Query: 229 FFQIENGDNLKVSGLIDRDD-NLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPP 1068
F + + N+ S +DR+ +L + +N S G+ + +L I + D NDN PQ++Q+ V+EN + + + + ARD D N+ Y + F I ++L++ I+RE ++VT+ A D GTP + ++ + ++DVNDN P+F S Y +++ ++++ATD D+ N +VTY + F +N ++R + L E Y + A D G T+ +H+ ++N P
Sbjct: 581 FIIVPDTGNINTSSKLDREQQSLYTLVHYVLNLSVTDHGVTQF--TSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGT-KVTMVTARDEDSGINSQIMYSLTGGDGVFSIEPSTGQ------IRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHVLDVNDNPPVFTSRVYERTMSEGNAAAGEFVVQVNATDADVERNGHVTY----TIMHGALGMFTINETTGVIRTQGVLNRES-KDFYTLIVMARDQGAVPYMDFGTIDVHVIDKNDNTP 849
BLAST of Protocadherin alpha-11 vs. Ensembl Nematostella
Match: EDO35412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK9]) HSP 1 Score: 187.193 bits (474), Expect = 6.668e-48 Identity = 194/683 (28.40%), Postives = 318/683 (46.56%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEP--TSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDC-FDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI---LLPGNNA--VIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAI-QSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP---FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEE--TLFIKAIDCGS--PRLTAIQQLTI 2376
+++Q+ D NDN P++ + + E+ +++ + A D D N Y I + F + + G + ++ +DRE ++ + + A D GTP+ G + I I+D ND+ P+F + Y SI N + ++ L++ A D D +N +++++ I + FDL+ ++R K++L E + Y F++ A D G P + TVT+++ + N P + LP +N IR EN I I +V D DS + + I + K E + + K DRE+ L + D G P+ +T + I + DVNDNSP F Y I E Q + QL A D D+G N + Y I L +V+ ++ + LDRE+ + + A D G ++GSTTV++ ++D NDN P F ++ Y + E +V+ A D D G NG +TY I F+LN +G L++ +DRET+ S Y+F++ A+D L ++V V + I D NDN P+F +P E Y + P G L+ V A D D G N+ I + + N FSI+ ++G + ST+ S+ H+ EE +L I A D G+ TA+ +T+
Sbjct: 81 VQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTN-PINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSI-LRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEV-KNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIR-SENSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGCF------KVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDL----GWFQVDFQSGLVTTAKPLDREQVSS-----VTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVS---ATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETK-SLYSFTVLAKDHGDPQLM---SSVKVELTISDINDNAPVF-YPVE--YFASIMENEPPGKLLQ-VTATDADEGTNAVISYDIIGGNNNGNFSIDSSTG--VISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTV 731 HSP 2 Score: 181.8 bits (460), Expect = 3.449e-46 Identity = 196/717 (27.34%), Postives = 317/717 (44.21%), Query Frame = 1
Query: 265 SGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQW---------------SQNSIV------IEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIA-IQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDL-VDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSP 2346
+G+I NL+ + F+ I N+L + I +LD NDN PQ S+NS++ I V + + EL DE +K+E YF ++L++ +DREL+ ++N+TL D G PS++ +LI + DVNDN P F S+ YT +I L N + L+++ATD D N T +S+ + F ++ + ++ K L E +S +I A DHG + TTVT+ + + N P + I E IG +L D DSG +G+ I +N N L T DRE K+ + KD G P +S ++ + I D+NDN+P F Y +I EN+P + Q+TA D D+G NA + Y I + N ++S+ +I+ + SLD E F + + A D G + + V++ +++ DN+PVF YN + E+ V A D NG ++Y+IV L ++G + + +DRE + +QY ++ AR L +A +V+I + D NDN P F + S+ + + VG +V A+D D+G N +++ L +L+ IN TSG + + L+ + + T+ + A D GSP
Sbjct: 262 TGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITNGDDE-----GCFKVEFLGFYF--------------IQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANI-SELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDL-GWFQVDFQSGLVTTAKPLDREQVSS-VTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTIS--EGASIGATVLQVSATDVDSGDNGRITYEISSSD-----AQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIM-ENEPPGKLLQVTATDADEGTNAVISYDIIGGNN----NGNFSIDSSTGVISTLASLDHE-VEEFFSLI----ISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENV---PKGTLVGRVYATTKD--KNGSISYAIVSGDPTNLFLVDSTGGIIKINGDMDRE-EKAQYLLAVIARVGTVKPL---SAQATVNIEVLDRNDNAPQF---STSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSNAEGLLW-INSTSGVIKLARKLTDGDETQYTVQVLASDSGSP 926 HSP 3 Score: 154.451 bits (389), Expect = 1.018e-37 Identity = 186/625 (29.76%), Postives = 287/625 (45.92%), Query Frame = 1
Query: 580 SNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLN----PFNAILRV--KKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFY-----HYTIFEENQP-NFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVE-SNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFY--NISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFIL--EEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRN 2397
SN G+ + IDRE + ++ L ++ PS + + +++ D+NDN+P F + +YT I ++++N+T + ATD D N T +++ F L P + L V KK L E Y+ +I A D G P + + + ++N + P + N+ + I EN GV IL D DSG +G +I ++D I + N + + + T + D EVK + D G P+ N A ++I ++D NDNSPQ + + I EN N IA + D D N+Q +I D KVE I +Q LDRE P + TD G P RS V I++ D+NDN P F Y NIS L +N V A DPD G NG V+YSI L F+++ SG + + +DRE Q S T +ITA+D + KT + +V++ I D NDN+P F+ +S+YK +S +G+ V V A D DSG N +I + + + + N LF +N +G L T + L K + + A D G P+L + ++ + I + +
Sbjct: 46 SNTGV---ISTTARIDRETTTQISLQLRTLN---PSNQ-PISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINT-ATDPDAGNNGTVDYTI-ASGDNTATFSLGTTACPTGSTLCVITKKPLDRET-TDFYQLNITATDRGTPALMGYCLINITILDENDHAP--VFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAI----DWDAIQS-NSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITNG----DDEGCFKVEFLGFYFIQLQKPLDRELVP-----FYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISEL-----AQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDRE-QVSSVTITITAQDHGS---APKTGSTTVTVTIIDGNDNKPRFM---KSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDIND 632 HSP 4 Score: 150.599 bits (379), Expect = 1.448e-36 Identity = 175/672 (26.04%), Postives = 296/672 (44.05%), Query Frame = 1
Query: 295 ELCAYRNVNFSCIWRG----ILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKA-RDSDEHPN---NISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFY-----TQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFN-AILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQS-LDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIV-RETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSG 2262
E + +N + RG + +C ++ I ILDEND+ P ++QNS + + ENTK L + A RDS + + I + I+ S + SS ++ ++ +D E+ + + ++A DGG PSK + I ++D NDN P + ++ ++I + +T I TD D N N + + CF + ++++K L E Y +++ D G P + V + + + N P+ N I E G +L D D G +G + SI + ++ + T K DRE + + + I +D G S +++ IID NDN P+F K Y TI E T+ Q++A D+D G N ++ Y I +S N L ++ + ++ +S LDRE + + + V+A D G+PQ S V + + DINDN PVF Y S +E+ + K+ A D D G N ++Y I+ F ++ ++G + + +D E + ++ I+A+D N KTA V+V+++ + DN P+F++ Y + VP G+LV V A KD N I + + LF ++ T G
Sbjct: 167 ETTDFYQLNITATDRGTPALMGYC------LINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTG-------VIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKI-TNGDDEGCFKVEFLGFYFIQLQKPLDRE-LVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPA--FTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSG-------LVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEIS--SSDAQVNGLFELNTQTGVLWTKSQLDRET-----KSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMEN----EPPGKLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVE-EFFSLIISAKDG-GNKYAAKTAVVNVTVL--NKADNLPVFLY---EMYNFTVYENVPKGTLVGRVYATTKDK--NGSISYAIVSGDPTNLFLVDSTGG 794 HSP 5 Score: 147.902 bits (372), Expect = 1.051e-35 Identity = 174/683 (25.48%), Postives = 292/683 (42.75%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELI---SWHNVTLLAVDG---GTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVES-NCQIIAIQSLDREKYPNG---FRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDS--PTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEE-TLFIKAIDCGSPRL-TAIQQLTIEI 2382
+ I I D ND+ + N+ V EN+ + L +I Y I +S+ F +S + + R +DRE + + NV ++ + T K +++ + D+NDN P+F + Y ++ L + + +I A D D N + +SL V D F +N L + K+L E S Y + A D S + + + + N P + P ++ + I E+ IG +++ D D G +G SI + M +S A LI K D E +L I +D G +++ +++ ++DVNDN+P F + T+ E F + + TA D D G NA + + + T P+K V S C+I I ++D E P G F+ V V+ATD G P+ S ++++++ D NDN P F + +S V A DPD NG VTYSI+ F L+P++G+L + P+ Y +I A D P+ R+T TV VS+ E P F + ++Y+ ++ G+ V V A S +N I++ L + F + +++G + T+ + G L + A+D P T+ +TI +
Sbjct: 1036 VTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLI--SSESHFAVDVRSGQ-----ITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITV-SELSLPGSPVFRIKAMDADEGDNAKFFYSL-VSGTGMDKFFINSSTGELHLSKTLDRET-TSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRP--VFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGN----LAAMFDVES---ATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQT----PSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLV----VMATDQGSPKLSTRKSITVQVTDENDNSPGFVS--------PPAAAAGSSLNVMTITAEDPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQI--PDNPTIYQLTIQASDGGQPS----RQTQTV-VSVFKEGPIGGGPTF---SSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGGFEVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITV 1673 HSP 6 Score: 146.362 bits (368), Expect = 2.940e-35 Identity = 171/674 (25.37%), Postives = 289/674 (42.88%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKI--EPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKY-PNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLL-PFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEI 2382
++ + +L++ DN+P + V EN + + A D++ +ISY + +PT+ + S GI +K+ +DRE + + + ++A G + + I+++D NDN P F +S ID + + A DLD N R+ L + +N + ++++ + L + ++Y + A D G P + S T+T+H+ +PP L ++ V ++ +Q + V D DSG +G+ SI + + K L K + +K LI+ D G P+F+ S ++I I D ND+ F + + + E + P + L AH LD + Y + S + + V S QI LDRE+ N V Q A + + V + + D+NDN PVF +A Y I+ E V A D D G N YS+V T + F +N ++GEL+ +DRET S Y + A D+ LY +T + I + D ND P+F ES+Y + ++ +GSLV + A DKD G N I++ + +F + +G L+ + L L I A D G L++ +T+ +
Sbjct: 726 VVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRV-YATTKDKN-GSISYAIVSGDPTNLFLV----DSTGGI---IKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVV-YNAAAVDLDAGKNGLVRYQLTSN--AEGLLWINSTSGVIKLARKLT-DGDETQYTVQVLASDSGSPPQHS--TMTIHITLSINHPPKFTL--SSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNEEGLFGIFPGGK--------LYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESHF----AVDVRSG-QITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSE---LSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLSKTLDRETT-SSYNLVVKATDASNANLY---STAKIEITVGDSNDQRPVF---PESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNV 1359 HSP 7 Score: 107.842 bits (268), Expect = 1.717e-23 Identity = 157/693 (22.66%), Postives = 278/693 (40.12%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAH-----------------DLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRE-----TQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
+E+ I D NDN P + ++EN L++ A D+DE N + Y I + S + S I L D E+ + ++ + A DGG + + + +++ DN P+F Y ++ N+ TL +++AT D N +++Y P + F ++ I+++ + E A I + +P+ ++ TV + + ++N P ++ ++ I +G V+ D D+G +G + N + +L +N T +I L K+ D + +T+ + + D G P PQ H T+ + P FT++ H D D G N QL Y I + L + ++ +SL + + + V ATD G P S S V+I + D ND+ +F + + E+ V +AH D D+ YS++ + F ++ SG++ + +DRE T + Y A + T + K + + + D NDN P+F + + Y I +S L GS V +KA+D D G N++ + L F IN ++GEL S L L +KA D + L + ++ I +G+
Sbjct: 623 VELTISDINDNAPVFYPVEYFASIMENEPPGKL-LQV-TATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASL----DHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVP-KGTLVGRVYATTKDKNGSISYAIVSGDP---TNLFLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPL-SAQATVNIEVLDRNDNAPQ--FSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLT--SNAEGLLWINSTS----GVIKL-ARKLTDGD-ETQYTVQVLASDSGSP-------------------PQHSTMTIHITLSINHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQG----NEEGLFGIFPGGKLYIRKSL-LQALKGSYDLI----VRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAEN---SSPGTLVGTLVAHALDHSRTKDIVYSLI-SSESHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVI---VTVTDLNDNAPVF---SRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGD 1256
BLAST of Protocadherin alpha-11 vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 177.563 bits (449), Expect = 8.909e-45 Identity = 180/674 (26.71%), Postives = 294/674 (43.62%), Query Frame = 1
Query: 403 DNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPT-----SKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETL--LPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPD 2403
+N PQ+S+ V E+ ++ + + A D D N + Y + P+ + YF I I + +RG+DRE + H + A DGG PS G + L I ++DVNDN PIFE + Y I + I + L + A+D D +N ++ + F + + + V K L E + Y + A D G P + TV + L + N P +A IR E+ + ++ T D D G +G+ I+ + + ++N+ E + + D E+ L++ +D G+P + I +IDVNDN+PQF + I E ++ A+D D G N ++ + + + N E+ I + LDREK P +F + + A D G P + G+ ++I L+DINDN P F Q Y+ S E+ + V A DPD G +V YSIV + F++NP L + Y FS++A D + TA V V++ D N + P F +Y ++ +G+ V V A D+D+G N++I + + FS++ET+G + T+ L + A D G P+L A + I I + + D
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATV-SASDPDSGSNGMIRYSMSPSQNLMSATYFSIDQ------ITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFV-LAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVPT-YTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIR--EDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMN-FFSINRINGE------VRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQNDLPFSIN-----ENTGGISIKEELDREKVP---KFT--FGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAEN---SRWGTSVLQVKAIDPDSGPT-NVVYSIVSSSGHDRCFRINPQG--LITLSCTLNYNTKHVYVFSVSASDG----MLSSTALVYVNVT--DSNTHAPEF---KRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPE--FSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDND 643 HSP 2 Score: 166.777 bits (421), Expect = 2.076e-41 Identity = 184/689 (26.71%), Postives = 313/689 (45.43%), Query Frame = 1
Query: 376 LEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKG-----IKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNI-LFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNE 2421
L I +LD NDN P + +N ++ E+ + F L + +A D+D N KY ++S+ N + + + + +DRE + + + + A D G P ++ ++ + I ++DVND P F Y+ +I ++ +N L + ATD D +N F + V + F +N N +RVK+ L +E + + A D G+P ++TTV + L + N P + ++ I EN +G D D G +G+ S ++ D+ ++N EN IS+ + DRE + I +D G P +A+I+I ++D+NDN P+F +E YH +I E ++ ++ Q+ A D D G + Y I S ++ ++ I +L+ + V + V A+D S + V + + D N + P F++ Y+ ED V +A D D G N ++YSI TL+P F ++ +G + + +DRE + Y F +TA D L K+ V I I D NDN+P+F+ P +Y+ ++ + G V V A D D G N+QI + F+I+ T G + T L E L + A D G+P A ++ + + + + DS P E
Sbjct: 114 LTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAV-RASDADSGSNG--------EVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQ-LVTTVRATDCDQGSNGEVFFEI-VSGNDMNFFSINRINGEVRVKQKLDYEMIGV-FNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFV--SSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQ---NDLPFSIN----ENTGGISI--KEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSG-PTNVVYSI---VSSSGHDRCFRINPQGLITLSCTLNYNT-----KHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKED---ASLGTSVLTVLATDRDTGSNAKISYSIA--TLVPEFSVDETTGVIKTAGSLDRE-KVDTYRFEVTATDHGIPQLKAKSF---VYIHIADVNDNDPVFLKP---SYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVK--DSPPLFE 753 HSP 3 Score: 160.999 bits (406), Expect = 1.010e-39 Identity = 174/640 (27.19%), Postives = 280/640 (43.75%), Query Frame = 1
Query: 364 NLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDIN-ANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQII-AIQSLDREKYPNGFRFVCPYQ--VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVR-ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGEL 2268
N ++I ++D NDN PQ+ + + EN + + + +A D D N + F I+ IK L DRE + + A D G P K G+ Q+ I ++D+NDN P F Y SI N +++ L++ A D D NV Y S+ CF +NP ++ + +L + Y FS+ A D + S V +++ + N + P +A ++ E+ +G +LT + D D+G + K + SI L + E +I T DRE + + D G P + + I I DVNDN P F K Y + E+ +P + +++A D D G NAQ+ Y S D ++S II ++ LDRE P Y+ V+ATD G P S V + L D+ D+ P+F++ Y ++ ED + V A D + YSIVR + F +NPN+G + + +D ETQ S+Y ++ A SP + +T +V + ++D NDN P+ + N +Q + P + A D D ++ ++ F + E ++N TSGEL
Sbjct: 321 NQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRV-QAYDKDHGTNGEITFSFMQNDLPFSINENTGGISIKEEL------DREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSV-LQVKAIDPDSGPTNVVY--SIVSSSGHDRCFRINP-QGLITLSCTLNYNT-KHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVK--EDASLGTSVLTVLATDRDTGSNAKISYSI-------ATLVPEFSVDETTGVIK--TAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSF---ASNGDGQGTFTIDSTQGIIRTLKPLDRETIPE-------YELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRS---PVITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPNTGAIQTLMKLDYETQ-SEYRLTVRATLSP---FFTET---TVMVYLKDINDNTPV-LEAFHMNINVQEGKVPPEARY--KIPAYDPD--VSDKLTFKVMEGNAKEWVTLNATSGEL 909
BLAST of Protocadherin alpha-11 vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 235.728 bits (600), Expect = 1.969e-63 Identity = 221/771 (28.66%), Postives = 351/771 (45.53%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIE--PTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPF-IVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPG------NNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNC-QIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDS-----------TPFN-----ETEESFLSDQATFIIVGIILGTFFICCGLVTGICTMAYRRWHSSNNRSPPNQLYQAGEELTNLQY 2613
I++ D NDN PQ+ + + I V ENT + + + +P A D D N ++ Y + P + F ++G K P L + +DREL +++T+ AVDGG P + L + + D NDN P FE Y + N + ++ L++ A D D+ N +SL+ V ++ I+ VK L E S F + A D G + SKT VT+ + +QN P++ + G + + I E+ +G + V D D G + C + + + + T S+N L T D E ++ I D G PA +++ + + + DVNDNSP F + EENQP TI +TA D D G NA+L Y I D+ + L +++ N ++ A LDRE + + F +V A D G P G+ TV I+++D NDN P F + Y+ S LE+ V V D D G N V S+ + F + +G + S DRE + S YTF + A D +++ V V+I + D NDN+P+ P+ S+++ QLS + S V +V+A D DSG N+ + F + LF I+ +SGE+ + ++ H G L ++ D G P A + I + E + S TP + + E SF + ++ I+ G+ G+V I + + R YQAG++ T Y
Sbjct: 120 IEVQDINDNTPQFPLSVLTISVPENTIMGALF-SIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSV-LQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYVKGPLDREEINS-LSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDST-SDNKRKYFLQTTTPLDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYI---KGLFEIDPNTGEVKARTPLDRE-HKERYEF----RVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVL---DMDKGENAHVHLSVEPDGGK-FVVQNGTGTILSSISFDREKE-SSYTFRLKAVDGGEP---PRSSYVGVTINVLDENDNDPVVTKPSNSSFR-QLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPYQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYVNETISNVSLVEALVGHSLYTPLDRDIAGDPESSFAAQRSN-----ILFGSLAGVAGVVILILAVVFIRHRIQRET---KSGYQAGKKETKDLY 861 HSP 2 Score: 140.198 bits (352), Expect = 3.344e-33 Identity = 147/541 (27.17%), Postives = 236/541 (43.62%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYK----IEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFE--------SSFYTQSIDCNLEINSTLDL-KIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNA---ILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQN----LYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGEL 1932
+L + + D NDN P++ S EV EN+ + L++ KA DSD PN Y ++P K I GI + ++ +DRE I+ + ++A D G K+ + I++ D NDN P E S +I ++ + + + L ++ D NA VT + +VPF ++ D N L+ L +E EYR I A+D G P S ++ + + + N ++ P+I + E G IL D DSG + + +I+ + ++ E A L DRE K R + + D G P +A + I ++D NDN P+F Y +++ E P + +T D+D G NA + ++ D K + I++ S DREK + + F ++ A D GEP RS V+I ++D NDN PV + N SF + V V A D D G N D+ +SI F+++P+SGE+
Sbjct: 229 LLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQV-KADDSDMGPNGEIEYSLHQAVDPVPKLLRID---RTTGI---IYVKGPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYFLQTTTPLDYERV-KEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIF------EVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYIKGLFEIDPNTGEVKARTPL------DREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHLSVEPDG-----GKFVVQNGTGTILSSISFDREKE-SSYTF----RLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKP-SNSSFRQLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPYQLFRISPSSGEI 738
BLAST of Protocadherin alpha-11 vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 235.728 bits (600), Expect = 8.208e-63 Identity = 203/680 (29.85%), Postives = 320/680 (47.06%), Query Frame = 1
Query: 382 IQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIE--PTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPF-IVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPG------NNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNC-QIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
I++ D NDN PQ+ + + I V ENT + + + +P A D D N ++ Y + P + F ++G K P L + +DREL +++T+ AVDGG P + L + + D NDN P FE Y + N + ++ L++ A D D+ N +SL+ V ++ I+ VK L E S F + A D G + SKT VT+ + +QN P++ + G + + I E+ +G + V D D G + C + + + + T S+N L T D E ++ I D G PA +++ + + + DVNDNSP F + EENQP TI +TA D D G NA+L Y I D+ + L +++ N ++ A LDRE + + F +V A D G P G+ TV I+++D NDN P F + Y+ S LE+ V V D D G N V S+ + F + +G + S DRE + S YTF + A D +++ V V+I + D NDN+P+ P+ S+++ QLS + S V +V+A D DSG N+ + F + LF I+ +SGE+ + ++ H G L ++ D G P A + I + E
Sbjct: 197 IEVQDINDNTPQFPLSVLTISVPENTIMGALF-SIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSV-LQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYVKGPLDREEINS-LSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDST-SDNKRKYFLQTTTPLDYERVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYI---KGLFEIDPNTGEVKARTPLDRE-HKERYEF----RVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVL---DMDKGENAHVHLSVEPDGGK-FVVQNGTGTILSSISFDREKE-SSYTFRLKAVDGGEP---PRSSYVGVTINVLDENDNDPVVTKPSNSSFR-QLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPYQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYVNE 855 HSP 2 Score: 140.584 bits (353), Expect = 3.377e-33 Identity = 147/541 (27.17%), Postives = 236/541 (43.62%), Query Frame = 1
Query: 373 ILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYK----IEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFE--------SSFYTQSIDCNLEINSTLDL-KIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNA---ILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQN----LYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGEL 1932
+L + + D NDN P++ S EV EN+ + L++ KA DSD PN Y ++P K I GI + ++ +DRE I+ + ++A D G K+ + I++ D NDN P E S +I ++ + + + L ++ D NA VT + +VPF ++ D N L+ L +E EYR I A+D G P S ++ + + + N ++ P+I + E G IL D DSG + + +I+ + ++ E A L DRE K R + + D G P +A + I ++D NDN P+F Y +++ E P + +T D+D G NA + ++ D K + I++ S DREK + + F ++ A D GEP RS V+I ++D NDN PV + N SF + V V A D D G N D+ +SI F+++P+SGE+
Sbjct: 306 LLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQV-KADDSDMGPNGEIEYSLHQAVDPVPKLLRI---DRTTGI---IYVKGPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGENAVVTCVVAGDVPFQLRPASDSTSDNKRKYFLQTTTPLDYE-RVKEYRVEIVAVDSGNPALSSTNSLKVQVTDVNDNSPVFSPTIF------EVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYIKGLFEIDPNTGEVKARTPL------DREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHLSVEPDG-----GKFVVQNGTGTILSSISFDREKE-SSYTF----RLKAVDGGEPPRSSYVGVTINVLDENDNDPVVTKP-SNSSFRQLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGNPYQLFRISPSSGEI 815
BLAST of Protocadherin alpha-11 vs. Ensembl Medaka
Match: si:ch73-379j16.2 (si:ch73-379j16.2 [Source:ZFIN;Acc:ZDB-GENE-141215-68]) HSP 1 Score: 211.46 bits (537), Expect = 1.861e-56 Identity = 188/661 (28.44%), Postives = 322/661 (48.71%), Query Frame = 1
Query: 133 ENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRF--------FQI-ENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLD--INANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVE-SNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISF------LEDFGSKKNSRKVAVFI-AHDPDFGVNGDVTYSIVRETLLP-FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIV 2055
E + VGSV+ NV D + K + R F++ EN L V IDR++ E + +N + + + + ++I+D NDN P + +++ E+T + ++P ARD D N + YK+ ++YF + + + PFL L++ +DRE + H + L AVDGG+P K+G+L + + ++D NDN PIF Y+ I+ N+++ S + + ++ATDLD +NA+V Y F + + + F +N + + VK + E A Y+ + A D G+P + V + + +QN P I + + + E+ G V+ + D DSG++GK CS+ + +D + + EN + SL+ + DRE + ++I D G+P +T +SI + DVNDN P+F + + E N P I ++A D D NA L Y ++ DT + + +I A++S D E F+F V+ATDSG P S + TV++ ++D NDN PV Y +S +E+ N+ + + A+D D G NG + +S+ + T F L+ +G++ + ET +++ I +D+ N+ TATV V +V
Sbjct: 38 EEVKVGSVV---GNVARDLGLDISSLKDRRARVVSGNEDAQFEVNENNGVLYVRKNIDREEICESISPCLINLKIVAEKPM-----EIHYVAVEIMDVNDNSPSFQDGEKTLDISESTPAGKRF-QMPTARDPDVALNTVRMYKLN-QNEYFNVKVREGEEDKIPFLVLQKPLDREKHAEHKLILTAVDGGSPPKSGTLNVTVTVLDTNDNSPIFTQEIYSAIINENIKVGSNV-ITVNATDLDEGVNADVEYSFGGELDPQIYEIFSINKHSGEISVKGEIDFEK-AEVYKLDVHASDKGQPPMNADCRVIIKVLDQNDNLPEIEVTSLSKSVS--EDSKPGTVVSLISITDRDSGLNGKVICSLQDSVPFD----LKPSFQEN--MYSLVVKQPLDRESVSHYDILITATDCGQPTLSTFKTVSIDVADVNDNKPEFTQNPVELYLTENNTPGNVICSVSALDKDLNENAILTYVVRGDTGQLISAAFLNINPETGEISALKSFDFESVKT-FQF----HVVATDSGSPPLSSNVTVNVFILDQNDNAPVI---LYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQQVTDHSLFALDRYTGQIRTLRSF-TETDEAEHKLLILVKDN-GNVSLSATATVIVKLV 668 HSP 2 Score: 147.132 bits (370), Expect = 1.380e-35 Identity = 169/622 (27.17%), Postives = 285/622 (45.82%), Query Frame = 1
Query: 583 NKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQ-LLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVT--YRFSLNVPF---IVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSI---LEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVI--ATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRET--LLP---FKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVP----VGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGE 2388
N G+ L +R+ IDRE I L K + + ++I+DVNDN P F+ T I + + A D D+ N Y+ + N F + + D PF L ++K L E A E++ + A+D G P + VT+ + + N P +A+I EN +G ++T D D G++ S L+P+ Y+I ++NK E I++ I D E +L + D G+P N + I ++D NDN P+ E ++ E+++P ++ ++ D D GLN ++ +Q D+ +D + E+ ++ Q LDRE V Y ++ ATD G+P S TVSI++ D+NDN P F Q + E+ + A D D N +TY + +T L+ +NP +GE+ + D E+ + + F + A DS + L ++ V+V++ I D NDN P+ ++P SN + +P G LVT V+A D D G N + F L++ + LF+++ +G++ T + + E L I D G+ L+A + +++ E
Sbjct: 81 NNGV---LYVRKNIDREEICESISPCLINLKIVAEKPMEIHYVAVEIMDVNDNSPSFQDGEKTLDISESTPAGKRFQMPT-ARDPDVALNTVRMYKLNQNEYFNVKVREGEEDKIPF---LVLQKPLDREKHA-EHKLILTAVDGGSPPKSGTLNVTVTVLDTNDNSPIFTQEIYSAIIN--ENIKVGSNVITVNATDLDEGVNADVEYSFGGELDPQIYEI-FSINKHSGE-ISVKGEI-----DFEKAEVYKLDVHASDKGQPPMNADCRVIIKVLDQNDNLPEIEVTSLSKSVSEDSKPGTVVSLISITDRDSGLNGKVICSLQ-DSVPFDLKPSFQ-ENMYSLVVKQPLDRES-------VSHYDILITATDCGQPTLSTFKTVSIDVADVNDNKPEFTQNPVELYLTEN---NTPGNVICSVSALDKDLNENAILTYVVRGDTGQLISAAFLNINPETGEISALKSFDFESVKT-FQFHVVATDSGSPPL---SSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQQVTDHSLFALDRYTGQIRTLRSFTETDEAEHKLLILVKDNGNVSLSATATVIVKLVE 669
BLAST of Protocadherin alpha-11 vs. Ensembl Medaka
Match: pcdh19 (protocadherin 19 [Source:NCBI gene;Acc:101169296]) HSP 1 Score: 213.772 bits (543), Expect = 4.296e-56 Identity = 202/730 (27.67%), Postives = 332/730 (45.48%), Query Frame = 1
Query: 34 KRIHFITIDLIFLLIPMVXXXXXXXXXXXXQIFENLPVGSVICKLSN-------VIIPRPSDTTKFKLIKN---RFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLD--INANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI-LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRI-QWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQ-----QAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIE-DCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLV 2163
K + I I +FLL +V+ + + I E + GSVI ++ I P+P ++I N R+ ++ L IDRD +C N CI + + + +++++I D NDN P++ + I IE+ EN + + L A D D + Y I P + + + L +++ +DRE S + + A DGG P K G++QL IK+ID NDN P+F+ S YT ++ N IN TL + ++ATD D N V Y F+ V ++ F ++P I+ V L +E + Y + A D G + VT+++ + N PP I LL N ++ + EN G VI V D DSG +GK C + ++ + + +S +++ + DRE K L I +D G P + + + + D NDN P F K Y + E N P + ++A D D G+N + Y I + D N + + + +I +++S D E Y F F +V+A D+G P S + TV I ++D+NDN PV +S + G V A D D G NG +TY+I F+++ +GE+ S + E S Y ++ ARD L +A+ + + + D N EPI + + L +++ +GS+ ++
Sbjct: 4 KEMELIQITTVFLLSWVVTEAVINLKYG---INEEMKPGSVIGNVTKDALKQGFQIAPQPP---YLRVISNSEPRWVELSPAGILTTQMKIDRD---VVCRQ---NPKCIISLEVMSNSMEICVIKVEIEDLNDNAPKFPTSHIDIEISENASPGTRF-PLEGASDPDSGIFGVQSYSITPNELFGLEIKTRGDGSKIAELVVQKSLDRETQSHYTYEISAEDGGDPPKIGAVQLNIKVIDSNDNNPVFDESVYTVNVMENSPIN-TLVIDLNATDPDEGTNGEVVYSFNSYVTEKTREAFKIDPRTGIITVNGVLDYET-SQIYEIDVQAKDLGPNSIPAHCKVTVNVMDTNDNPPVISLLSLNTEMVEVSENAQRGYVIALVRVSDKDSGANGKVQCRL----QGNVPFRLQEYES----FSTILVDGKLDREQKDTFNLTIQAEDSGTPPLRATKSLVVKVTDENDNPPHFLKPHYQEMVMENNLPGSCLLAVSAEDPDLGMNGTVSYSIVPGEIKHMDVNTYVSINPSGRIYSMRSFDHE-YTRTFDF----KVLARDNGNPSLSSNATVRIVVLDVNDNTPVMTNPPLVNGTAEVSIPRNAGV---GYMVTQVKADDYDEGENGRLTYTISEGDRAFFEIDQVNGEVRSTRMFG-ENAKSSYEITVVARDHGKPSL---SASAYIMVYLSPDLNAQEPI------GSVNLSLIFIIALGSIAAIL 692 HSP 2 Score: 134.42 bits (337), Expect = 2.674e-31 Identity = 181/709 (25.53%), Postives = 304/709 (42.88%), Query Frame = 1
Query: 532 YKIEPTSKYFFISSEKSNKGIK----PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLD--INANVTYRFSLNVPFIVQ-----DCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGK----FNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSP-----QFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNP-----NSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVP----VGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPD---STPFNETEESFLSDQATFII-VGIILGTFFICCGLVTGICTMAYRRWHSSNNR 2559
++I P Y + S + ++ L + IDR+++ N + + + ++I D+NDN P F +S I N + L+ A+D D I +Y + N F ++ D + A L V+KSL E S Y + I A D G P + + + + + N P + + + ++EN I +++ D D G +G+ FN + E K + +T II++ N + D E ++ + KD G + ++++ ++D NDN P E + E Q + IA + D D G N +++ R+Q + P +L + ES I+ LDRE+ + F + A DSG P + ++ +++ D NDN P F + Y +E+ + S +AV A DPD G+NG V+YSIV + +N SG +YS D E + + F + ARD+ L ++ +V IV+ D NDN P+ P N ++S +P VG +VT VKA D D G N ++ + + E R F I++ +GE+ ++ + K + + A D G P L+A + + + +PD P S + FII +G I FI V C + + N R
Sbjct: 54 FQIAPQPPYLRVISNSEPRWVELSPAGILTTQMKIDRDVVCRQNPKCIISLEVMSNSMEICVIKVEIEDLNDNAPKFPTSHIDIEISENASPGTRFPLE-GASDPDSGIFGVQSYSITPNELFGLEIKTRGDGSKI----AELVVQKSLDRET-QSHYTYEISAEDGGDPPKIGAVQLNIKVIDSNDNNP--VFDESVYTVNVMENSPINTLVIDLNATDPDEGTNGEVVYSFNSYVTE-KTREAFKIDPRT-----GIITV--NGVLDYETSQIYEIDVQAKDLGPNSIPAHCKVTVNVMDTNDNPPVISLLSLNTEMVE--VSENAQRGYVIALVRVSDKDSGANGKVQCRLQGNV----PFRLQEYESFSTILVDGKLDREQK-DTFNLT----IQAEDSGTPPLRATKSLVVKVTDENDNPPHFLKPHYQEMVMEN--NLPGSCLLAVS-AEDPDLGMNGTVSYSIVPGEIKHMDVNTYVSINPSGRIYSMRSFDHEYTRT-FDFKVLARDNGNPSL---SSNATVRIVVLDVNDNTPVMTNPPLVNGTAEVS--IPRNAGVGYMVTQVKADDYDEGENGRLTYTISEGDR-AFFEIDQVNGEVRSTRMFGENAKSSYEITVVARDHGKPSLSASAYIMV----YLSPDLNAQEPIGSVNLSLI-----FIIALGSIAAILFITMIFVAVKCKRDNKEIRTYNCR 716
BLAST of Protocadherin alpha-11 vs. Ensembl Medaka
Match: pcdh9 (protocadherin 9 [Source:NCBI gene;Acc:101156238]) HSP 1 Score: 211.075 bits (536), Expect = 2.054e-55 Identity = 189/671 (28.17%), Postives = 321/671 (47.84%), Query Frame = 1
Query: 367 LKILEIQIL--DENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIK-PFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDI--NANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSI----LLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPV-GSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPR 2349
++++I+I+ D NDN P + I I + ENT ++S + +P A D D PN++ Y++ F + ++ +G K P L +++ +DRE + + + DGG+P K+ + L + + DVNDNKP+F + I N I +++ +++ ATD DI NA + Y F V + F LN + ++ V++ L E A ++ S+ A D ++ TV +++ + N PP+I ++ N + + E I I V D D+ ++GK C I + + + K +N ++ T+ + D E I D GKP+ N +A + + + D NDN P F + + E N+ + + L+A D D G NA++ Y++ + S +D ++ V + A + DRE + RF+ + V A D+G P V + ++D NDN P F + E+ V V D D G N ++ SI+ + F L+P SG + S DRE Q S YTF + A DS ++ V+I + D NDN PI I+P SN +L L + GS+V V A+D D+G+N+++++ + LF I+ +G + + G L + D G P+
Sbjct: 122 FRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRF-AIPSATDPDTGPNSVHKYELINGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSV-VQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAI-HKLSVLASDGSS--SPARATVIINVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDVPFHL-----KAVYDNQYLLE--TSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLGPNASFFDLDRKTGV-----LTASRVFDRE---DQDRFL--FTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENL---PKYSTVGVITVTDSDAGENAAISLSILNDN-ENFILDPFSGVIKSNVSFDREQQ-SSYTFDVRAIDSGRPPC---SSAAKVTINVIDVNDNTPIVIYP-PSNTSFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDIGLHRLVVNISDLGYPK 761 HSP 2 Score: 120.553 bits (301), Expect = 4.820e-27 Identity = 154/587 (26.24%), Postives = 257/587 (43.78%), Query Frame = 1
Query: 712 IKII--DVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAI-------LRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFN---CSILEPKNYDIILTMNKTKSENIAIISLIT-NKIFDREVKTRIQLIIFCKD-FGKPAFNTSAEXXXXXXDVNDNSPQFEKEF----YHYTIF--EENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTP 2412
IKII D NDN P+F S SI N INS + ATD D N +++ L Q F L+ L V+++L E Y I D G P + S + + + + N P + N + I EN IG ++ D D G + + + + + P + +N T LIT + DRE +L + D PA A + I + DVNDN P + + + T+F E++ N IA +T D D +N ++ I+ D P L V N ++ +L + + F +++A+DSG+P + + V + L D NDN P+F Q ++ +E+ K + A D D G N ++ Y + F L+ +G L + + DRE Q ++ F++TARD+ T L + A + + + D NDN P F ++++ +S +P S V ++ D D+G N+ I + + N F ++ SG + ++ + T ++AID G P ++ ++TI + + D+TP
Sbjct: 127 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIP-SATDPDTGPNSVHKYEL---INGQSAFGLDIVETPEGEKWPQLIVQQNLDREQ-KDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKP--VFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKR-LFALNSTS-------GLITVQRPLDREETAIHKLSVLASDGSSSPA---RATVIINVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDV----PFHLKAVYDNQYLLETSALLDYEGTKEYNF----KIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMEN---NKRDLFLTTLSATDEDSGKNAEIVYQLGPNASF-FDLDRKTGVLTASRVFDREDQ-DRFLFTVTARDNGTPPLQAQAAVI---VTVLDENDNNPKF---THNHFQFFVSENLPKYSTVGVITVTDSDAGENAAISLSILNDNEN--FILDPFSGVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTINVIDVN--DNTP 672 HSP 3 Score: 101.679 bits (252), Expect = 2.403e-21 Identity = 87/320 (27.19%), Postives = 143/320 (44.69%), Query Frame = 1
Query: 256 LKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDI-GVVILTGVVKDNDSGMDGKFNCSILEPKN 1212
L+ S L+D + E NF + N ++ +++ DENDN P ++Q I + V+EN K D F L A D D N Y++ P + +F + + L R DRE T+ A D GTP +++ ++D NDN P F + + + NL ST+ + I TD D N S+ + F L+PF+ +++ S E S Y F + A+D GRP S VT+++ + N P ++ P +N +++ I G V+ D+D+GM+ + +I+ N
Sbjct: 420 LETSALLDYEGTKEY------NFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTL-SATDEDSGKNAEIVYQLGPNASFFDLDRKTG------VLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGV-ITVTDSDAGENAAISLSI---LNDNENFILDPFSGVIKSNVSFDREQ-QSSYTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVSGNN 721
BLAST of Protocadherin alpha-11 vs. Planmine SMEST
Match: SMESG000012176.1 (SMESG000012176.1) HSP 1 Score: 1715.28 bits (4441), Expect = 0.000e+0 Identity = 868/876 (99.09%), Postives = 868/876 (99.09%), Query Frame = 1
Query: 19 MSIIFKRIHFITIDLIFLLIPMVXXXXXXXXXXXXQIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIVGIILGTFFICCGLVTGICTMAYRRWHSSNNRSPPNQLYQAGEELTNLQYIDNYLIMKEMS 2646
MSIIFKRIHFITIDLIFLLIPMVSSLLSSESPISIQIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKN DIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEISIIIIDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFV VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKN RKVAVFIAHDPDFGVNGDVTYSIV ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATV VSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIVGIILGTFFICCGLVTGICTMAYRRWHSSNNRSPPNQLYQAGEELTNLQYIDNYLIMKEMS
Sbjct: 1 MSIIFKRIHFITIDLIFLLIPMVSSLLSSESPISIQIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNNDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEISIIIIDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFV----VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNLRKVAVFIAHDPDFGVNGDVTYSIVSETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVLVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIVGIILGTFFICCGLVTGICTMAYRRWHSSNNRSPPNQLYQAGEELTNLQYIDNYLIMKEMS 872
BLAST of Protocadherin alpha-11 vs. Planmine SMEST
Match: SMESG000012176.1 (SMESG000012176.1) HSP 1 Score: 1674.83 bits (4336), Expect = 0.000e+0 Identity = 833/841 (99.05%), Postives = 833/841 (99.05%), Query Frame = 1
Query: 124 QIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIVGIILGTFFICCGLVTGICTMAYRRWHSSNNRSPPNQLYQAGEELTNLQYIDNYLIMKEMS 2646
QIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKN DIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEISIIIIDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFV VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKN RKVAVFIAHDPDFGVNGDVTYSIV ETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATV VSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIVGIILGTFFICCGLVTGICTMAYRRWHSSNNRSPPNQLYQAGEELTNLQYIDNYLIMKEMS
Sbjct: 15 QIFENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDINANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILLPGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNNDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEISIIIIDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFV----VIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNLRKVAVFIAHDPDFGVNGDVTYSIVSETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVLVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFLSDQATFIIVGIILGTFFICCGLVTGICTMAYRRWHSSNNRSPPNQLYQAGEELTNLQYIDNYLIMKEMS 851
BLAST of Protocadherin alpha-11 vs. Planmine SMEST
Match: SMESG000022902.1 (SMESG000022902.1) HSP 1 Score: 476.863 bits (1226), Expect = 1.456e-150 Identity = 315/852 (36.97%), Postives = 460/852 (53.99%), Query Frame = 1
Query: 55 IDLIFLLIPMVXXXXXXXXXXXXQIF----ENLPVGSVICKLSNVIIPRPSDTTKFKLIKNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRGILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKYFFISSEKSNKGIKPFLKLRRG--IDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDIN--ANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL-----PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFGSKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRL-TAIQQLTIEIGEFR------NPDSTPFNETEESFLS----DQATFIIVGIILGTFFICCGLVTGICTMAYRR 2538
I +IFLL ++ S QIF EN+ +G+ I L ++ KF L N +F I L +DRD + ELC +C W +L G IL+I I D NDN P+W N I +++ ENT+ + LE P A D D N I YY I P S F++S + N P L L +G +DREL SWHN+TL+A DGG +G++ + I+I+D NDN P+F+SSFY ID ++ +TL L+IHA DLD +TY+FSL+ P V + F ++P A + KSL + Y F I A D G P + ++T++ + + ++N + P I + P + +I + EN I ++ + + D DSG++ KFNCS+ + D L +K K + I L T + FDRE+++ + + I C+D G P S +I I + D+ND+SP F+ Y E N PN + + A D+D G NA+LRY+I W + + K++S ++ A LDRE P G+ F QV+A D G+P +S ST V IEL D+ND P F + Y ED+G+ + V A D D N V Y + +E +PF+++ SG +Y+ L+DRE+ ++F A D+P NLLYRKTATV +++ I D NDN+P FIFPNE+ I LSY V V A D+D+GIN++I++I+ + LFS+N +G + +T L +KG E L IKAID G ++ TA+ Q+ I+I F+ D P NE+ FL + II+ I+L T I C L+ IC MA RR
Sbjct: 2 IRVIFLLSTIIVRYSISILQNQRQIFLDIDENIEIGTRIIDLQTKLLSNEEKNIKFSLTSNPYFHIRENSVLYTKSFLDRDKDRELCHNSEFPANCQWSRLLTLGNGGYYILKITINDVNDNPPKWEINHIHLKISENTQ-PGYKLEFPLATDDDFGINGIQYYTIFPISSVFYVS-DSGNGERSPRLVLSKGSKLDRELNSWHNMTLVAYDGGINKLSGTVPVSIEILDENDNGPVFQSSFYNVLIDEDIMPGTTLPLRIHAYDLDAGNFGKITYKFSLSTPQHVLEIFSISPNTANIITSKSLNFKSRRKFYDFEIVAQDGGIPPKTAQTSIKVEIVDKNTHAPEIKVTPMPDPTSKNII-VPENSAINRIVASFTINDKDSGINSKFNCSLTGLNSKDFNLKHSK-KLGKLEIYVLETKRSFDRELESLLTVCISCQDQGVPQLTGSQDILIEVEDINDHSPVFQHPEYRLRTTEGNAPNSLVYHILATDMDKGDNARLRYKIIW-PDIETQSLPFKIDSEGRLFAKYVLDREANPQGYTF----QVMAFDYGDPSKSASTIVKIELEDLNDCPPKFNRDHYQFQIKEDYGNIHIRQHVGDVYAEDLDLQENAIVFYRLSQEINVPFEIDSKSGSIYTSKLIDRESVSVPFSFLCMAVDNPFNLLYRKTATVEITVTIIDVNDNKPQFIFPNETQQDINLSYYARKEHFVGKVIANDQDAGINAKIKYIITQGNALKLFSLNNDTGVINLNTDLKPSNKGYELLTIKAIDSGQFQIHTAVCQIRIKISNFQLITKPEYKDQKPSNES--GFLHFDWWEPNKMIIIIILLVTALISCILIGAICVMAKRR 842
BLAST of Protocadherin alpha-11 vs. Planmine SMEST
Match: SMESG000063589.1 (SMESG000063589.1) HSP 1 Score: 348.591 bits (893), Expect = 2.073e-102 Identity = 274/828 (33.09%), Postives = 413/828 (49.88%), Query Frame = 1
Query: 127 IFENLPVGSVICKLSNVIIPRPSDTTKFKLI----KNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRG-ILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKY---FFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDIN--ANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL--------PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFG--SKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFL------SDQATFIIVGIILG-TFFICCGLVTGICTMA 2529
I+EN+P+ + L I D K++L+ +N++F + +L V IDRD N +LC F C+W G I+F G N + L I+I D NDN+P W+ I+IE++EN ++L +A+D D PNN+ Y++ ++KY F ++ E GI P L + +D E ++TL A DG P +GS+ + IKI+D NDN P FE S ++ +I N + L L + A D D +V Y S + P F +N + I+ V +++ ++ + F + A D G P S V + +K+ N PP+IL+ N +V+ I+EN IG + D+DS NC++ ++ ++ N K + I LI NK+FDRE ++ I++ + C D G P +S + II+ DVNDN+P F+K Y Y + EEN PN IA+L A D D G N +L Y I ++ DP IKV N +IIA+Q LDRE G++F Q+IA D G+ RSG+T V I L DIND P F Y ED G S + V D D G NG ++ I+ + PFK++ N + + +DRE + Y ++ A D + R T + V+I + D NDN P F P + I +S G + T ++A D D G N+++ + + LF I +G L + K T+ I A D G+P L++ + I + + TP TE + L S Q I++ II+ T IC GL+T IC MA
Sbjct: 11 IYENVPLNVSVVNLRPEIEKSQKDF-KYELLMGLSQNKYFYVNKNYDLIVLTNIDRDRNPDLCKEMTTEFLCVWTGVIMFEGYNVIISLRIEIKDVNDNIPFWNH-PILIEIMENNPPGK-TIDLTQAQDDDSPPNNVQRYELM-SNKYSSIFRLTKEPGPSGIIPRLTILTVLDHEKYKEFSLTLNAFDGAYPYHSGSVNISIKILDQNDNAPKFEKSHFSLTIPENYPLFKPLMLNLTAVDDDSGQFGSVIYYISESSPPDSLKKFSINN-HGIITVIRNIDYDIGEKLFTFIVVAKDQGNPPLSSLAMVKITIKDVNDQPPTILINSYSTSGSKNNPSVLSIVENNSIGQAVARISATDSDSFESDFCNCTLTHFSDFQLVFERNVAK---MTIYRLIANKVFDRETRSIIKVTVICSDTGYPPMTSSETLRIIVEDVNDNNPIFDKNVYSYVVAEENAPNTIIAKLRATDDDAGKNGKLTYNISPNSKFRDPRPAIKVNENGEIIAVQPLDRESNLQGYKF----QIIAIDQGDNPRSGTTIVVIHLNDINDCKPKFSDDSYFFQLEEDSGISSIFRPKIVGSIKVTDADIGKNGISSFEILPKN-SPFKIDENK-YIKTTRFIDREHR-KNYMLTVLAVDGLADSEIRHTTSTVVNITVTDVNDNAPQFYIPKNLSIPINVSLYEEPGFVFTNLQATDSDEGENARVTYHISGGNIFGLFEIESQTGRLSVRDHIQSKLKVPFTVTILARDHGTPSLSSTVVIRILLTD------TPAIGTEINKLNNRTASSTQTNQILIMIIVTITCVICIGLITIICLMA 817
BLAST of Protocadherin alpha-11 vs. Planmine SMEST
Match: SMESG000063589.1 (SMESG000063589.1) HSP 1 Score: 348.206 bits (892), Expect = 4.388e-102 Identity = 274/828 (33.09%), Postives = 413/828 (49.88%), Query Frame = 1
Query: 127 IFENLPVGSVICKLSNVIIPRPSDTTKFKLI----KNRFFQIENGDNLKVSGLIDRDDNLELCAYRNVNFSCIWRG-ILFCGTNNLKILEIQILDENDNVPQWSQNSIVIEVVENTKLDSFYLELPKARDSDEHPNNISYYKIEPTSKY---FFISSEKSNKGIKPFLKLRRGIDRELISWHNVTLLAVDGGTPSKTGSLQLLIKIIDVNDNKPIFESSFYTQSIDCNLEINSTLDLKIHATDLDIN--ANVTYRFSLNVPFIVQDCFDLNPFNAILRVKKSLKHECFASEYRFSIDALDHGRPVEKSKTTVTLHLKNQNLYPPSILL--------PGNNAVIRIIENQDIGVVILTGVVKDNDSGMDGKFNCSILEPKNYDIILTMNKTKSENIAIISLITNKIFDREVKTRIQLIIFCKDFGKPAFNTSAEXXXXXXDVNDNSPQFEKEFYHYTIFEENQPNFTIAQLTAHDLDDGLNAQLRYRIQWDTSLYDPNKLIKVESNCQIIAIQSLDREKYPNGFRFVCPYQVIATDSGEPQRSGSTTVSIELMDINDNIPVFQQAFYNISFLEDFG--SKKNSRKVAVFIAHDPDFGVNGDVTYSIVRETLLPFKLNPNSGELYSYDLVDRETQPSQYTFSITARDSPTNLLYRKTATVSVSIVIEDCNDNEPIFIFPNESNYKIQLSYLVPVGSLVTLVKAIDKDSGINSQIQFILEEEKRNILFSINETSGELLTSTVLSVIHKGEETLFIKAIDCGSPRLTAIQQLTIEIGEFRNPDSTPFNETEESFL------SDQATFIIVGIILG-TFFICCGLVTGICTMA 2529
I+EN+P+ + L I D K++L+ +N++F + +L V IDRD N +LC F C+W G I+F G N + L I+I D NDN+P W+ I+IE++EN ++L +A+D D PNN+ Y++ ++KY F ++ E GI P L + +D E ++TL A DG P +GS+ + IKI+D NDN P FE S ++ +I N + L L + A D D +V Y S + P F +N + I+ V +++ ++ + F + A D G P S V + +K+ N PP+IL+ N +V+ I+EN IG + D+DS NC++ ++ ++ N K + I LI NK+FDRE ++ I++ + C D G P +S + II+ DVNDN+P F+K Y Y + EEN PN IA+L A D D G N +L Y I ++ DP IKV N +IIA+Q LDRE G++F Q+IA D G+ RSG+T V I L DIND P F Y ED G S + V D D G NG ++ I+ + PFK++ N + + +DRE + Y ++ A D + R T + V+I + D NDN P F P + I +S G + T ++A D D G N+++ + + LF I +G L + K T+ I A D G+P L++ + I + + TP TE + L S Q I++ II+ T IC GL+T IC MA
Sbjct: 29 IYENVPLNVSVVNLRPEIEKSQKDF-KYELLMGLSQNKYFYVNKNYDLIVLTNIDRDRNPDLCKEMTTEFLCVWTGVIMFEGYNVIISLRIEIKDVNDNIPFWNH-PILIEIMENNPPGK-TIDLTQAQDDDSPPNNVQRYELM-SNKYSSIFRLTKEPGPSGIIPRLTILTVLDHEKYKEFSLTLNAFDGAYPYHSGSVNISIKILDQNDNAPKFEKSHFSLTIPENYPLFKPLMLNLTAVDDDSGQFGSVIYYISESSPPDSLKKFSINN-HGIITVIRNIDYDIGEKLFTFIVVAKDQGNPPLSSLAMVKITIKDVNDQPPTILINSYSTSGSKNNPSVLSIVENNSIGQAVARISATDSDSFESDFCNCTLTHFSDFQLVFERNVAK---MTIYRLIANKVFDRETRSIIKVTVICSDTGYPPMTSSETLRIIVEDVNDNNPIFDKNVYSYVVAEENAPNTIIAKLRATDDDAGKNGKLTYNISPNSKFRDPRPAIKVNENGEIIAVQPLDRESNLQGYKF----QIIAIDQGDNPRSGTTIVVIHLNDINDCKPKFSDDSYFFQLEEDSGISSIFRPKIVGSIKVTDADIGKNGISSFEILPKN-SPFKIDENK-YIKTTRFIDREHR-KNYMLTVLAVDGLADSEIRHTTSTVVNITVTDVNDNAPQFYIPKNLSIPINVSLYEEPGFVFTNLQATDSDEGENARVTYHISGGNIFGLFEIESQTGRLSVRDHIQSKLKVPFTVTILARDHGTPSLSSTVVIRILLTD------TPAIGTEINKLNNRTASSTQTNQILIMIIVTITCVICIGLITIICLMA 835 The following BLAST results are available for this feature:
BLAST of Protocadherin alpha-11 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin alpha-11 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin alpha-11 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin alpha-11 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin alpha-11 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin alpha-11 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin alpha-11 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin alpha-11 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin alpha-11 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin alpha-11 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin alpha-11 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin alpha-11 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin alpha-11 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin alpha-11 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021961 ID=SMED30021961|Name=Protocadherin alpha-11|organism=Schmidtea mediterranea sexual|type=transcript|length=3685bpback to top protein sequence of SMED30021961-orf-1 >SMED30021961-orf-1 ID=SMED30021961-orf-1|Name=SMED30021961-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=877bp MSIIFKRIHFITIDLIFLLIPMVSSLLSSESPISIQIFENLPVGSVICKLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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