6-phosphogluconate dehydrogenase, decarboxylating

Overview
Name6-phosphogluconate dehydrogenase, decarboxylating
Smed IDSMED30021922
Length (bp)1677
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of 6-phosphogluconate dehydrogenase, decarboxylating (SMED30021922) t-SNE clustered cells

Violin plots show distribution of expression levels for 6-phosphogluconate dehydrogenase, decarboxylating (SMED30021922) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of 6-phosphogluconate dehydrogenase, decarboxylating (SMED30021922) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for 6-phosphogluconate dehydrogenase, decarboxylating (SMED30021922) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30021922

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30021922h1SMcG0014360 SmedASXL_016291SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30021922h1SMcG0014360 dd_Smed_v4_8829_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30021922h1SMcG0014360 dd_Smed_v4_8829_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30021922h1SMcG0014360 dd_Smed_v6_8829_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30021922h1SMcG0014360 dd_Smed_v6_8829_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Human
Match: PGD (phosphogluconate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8891])

HSP 1 Score: 642.884 bits (1657), Expect = 0.000e+0
Identity = 312/479 (65.14%), Postives = 378/479 (78.91%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +D FL N  K T V+GA+SL+E VSKLK PR+I+LLVKAGQAVDDFI  L+PLL++GDIIIDGGNSE+ D+TRRCR L  K ILFVGSGVSGGEEGARYGPSLMPGGN EAW HI+ IFQ IAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M  DE+++ F+ WNK+EL+SFLIEIT  I KFQ+ +G++LL +I DSAGQKGTGKWTAI+AL+ GVPVTLI E+VFARCLS LK  R++ASK+       +F G+K  FL D++ ALYASKIISY QGFM+++ A+ +  W+LN G IALMWRGGCIIRS FL  IK+A++++  L  LL D++F+  +  CQ SWR+ VST V  G+P P F++AL+FYDG R E LPA+L+QAQRD FGAH Y+LL  P  + H NWTG  G+ ++S+Y
Sbjct:    3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSY 481
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Human
Match: PGD (phosphogluconate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8891])

HSP 1 Score: 354.369 bits (908), Expect = 1.777e-119
Identity = 187/277 (67.51%), Postives = 212/277 (76.53%), Query Frame = 2 
Query:   56 DLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLI 886
            D+ LIGLAVMGQNL+LNM   GF VC FNRT+  +D FL N  K T V+GA+SL+E VSKLK PR+I+LLVKAGQAVDDFI  L                      RRCR L  K ILFVGSGVSGGEEGARYGPSLMPGGN EAW HI+ IFQ IAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M  DE+++ F+ WNK+EL+SFLIEIT  I KFQ+ +G++LL +I DSAGQKGTGKWTAI+AL+ GVPVTLI
Sbjct:    2 DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKL----------------------RRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLI 256
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Human
Match: PGD (phosphogluconate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8891])

HSP 1 Score: 300.442 bits (768), Expect = 3.549e-99
Identity = 152/205 (74.15%), Postives = 171/205 (83.41%), Query Frame = 2 
Query:   83 MGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISE 697
            MGQNL+LNM   GF VC FNRT+  +D FL N  K T V+GA+SL+E VSKLK PR+I+LLVKAGQAVDDFI  L+PLL++GDIIIDGGNSE+ D+TRRCR L  K ILFVGSGVSGGEEGARYGPSLMPGGN EAW HI+ IFQ IAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M  DE+++
Sbjct:    1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQ 205
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Human
Match: PGD (phosphogluconate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8891])

HSP 1 Score: 279.256 bits (713), Expect = 1.107e-90
Identity = 130/196 (66.33%), Postives = 159/196 (81.12%), Query Frame = 2 
Query:  563 VGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIR 1150
            VG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M  DE+++ F+ WNK+EL+SFLIEIT  I KFQ+ +G++LL +I DSAGQKGTGKWTAI+AL+ GVPVTLI E+VFARCLS LK  R++ASK+       +F G+K  FL D++ ALYASKIISY QGFM+++ A+ +  W+LN G IALMWRGGCIIR
Sbjct:   29 VGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIR 224
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Human
Match: PGD (phosphogluconate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8891])

HSP 1 Score: 222.246 bits (565), Expect = 1.547e-69
Identity = 117/160 (73.12%), Postives = 131/160 (81.88%), Query Frame = 2 
Query:   83 MGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDW 562
            MGQNL+LNM   GF VC FNRT+  +D FL N  K T V+GA+SL+E VSKLK PR+I+LLVKAGQAVDDFI  L+PLL++GDIIIDGGNSE+ D+TRRCR L  K ILFVGSGVSGGEEGARYGPSLMPGGN EAW HI+ IFQ IAAKV   EPCCDW
Sbjct:    1 MGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDW 160
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Celegans
Match: T25B9.9 (6-phosphogluconate dehydrogenase, decarboxylating [Source:UniProtKB/Swiss-Prot;Acc:Q17761])

HSP 1 Score: 584.334 bits (1505), Expect = 0.000e+0
Identity = 292/480 (60.83%), Postives = 355/480 (73.96%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSN--SSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
            AD+ +IGLAVMGQNL+LNM   GF VC FNRT+ ++D FL N  K T +IGA S+EE   KLK PR++M+L+KAG  VD  I+ ++P L  GDIIIDGGNSE+ DS RR  QLA K I+FVG GVSGGEEGAR+GPSLMPGGN +AW H++ IFQ IAAK  N EPCCDWVG  GSGHFVKMVHNGIEYGDMQLI EAYHL+   + + +D+++E  D WNK ELESFLIEIT  I K+++E GE ++ +I DSAGQKGTGKWT   AL+ G+PVTLI E+VFARCLS LK  R+ ASK+ P    S      +K  F+  +  ALYASKI+SY QGFM++  AS Q  W+LN G IALMWRGGCIIRSRFL +I+ A++K++ LS LL D++F + I + Q SWR VV  AV  G+P PAFSSALAFYDG  +E +PANLLQAQRD FGAH Y+LL  P  + H NWTGT G   ++ Y
Sbjct:    4 ADIAVIGLAVMGQNLILNMNDHGFTVCAFNRTVKLVDDFLANEAKGTKIIGAHSIEEMCKKLKRPRRVMMLIKAGTPVDMMIDAIVPHLEEGDIIIDGGNSEYTDSNRRSEQLAAKGIMFVGCGVSGGEEGARFGPSLMPGGNPKAWPHLKDIFQKIAAK-SNGEPCCDWVGNAGSGHFVKMVHNGIEYGDMQLIAEAYHLLSKAVELNHDQMAEVLDDWNKGELESFLIEITANILKYRDEQGEPIVPKIRDSAGQKGTGKWTCFAALEYGLPVTLIGEAVFARCLSALKDERVRASKQLPRPQVSPDTVVQDKRVFIKQISKALYASKIVSYAQGFMLLAEASKQFNWNLNFGAIALMWRGGCIIRSRFLGDIEHAFQKNKQLSNLLLDDFFTKAITEAQDSWRVVVCAAVRLGIPVPAFSSALAFYDGYTSEVVPANLLQAQRDYFGAHTYELLAKPGTWVHTNWTGTGGRVTSNAY 482
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Fly
Match: Pgd (gene:FBgn0004654 transcript:FBtr0070384)

HSP 1 Score: 600.127 bits (1546), Expect = 0.000e+0
Identity = 302/479 (63.05%), Postives = 369/479 (77.04%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQNL+LNM  +GF VC +NRT+  + +FL N  K T VIGA SLE+ VSKLKSPRK+MLLVKAG AVDDFI  L+PLL++GD+IIDGGNSE+ D++RRC +LA+  +LFVGSGVSGGEEGAR+GPSLMPGG+  AW  IQPIFQAI AK  + EPCC+WVG  G+GHFVKMVHNGIEYGDMQLICEAYH+M+  L +  D++++ F  WN +EL+SFLIEIT  I K+++  G YLL +I D+AGQKGTGKWTAI AL  GVPVTLI E+VF+RCLS LK  R++AS      S+     N  +FL+D+K ALY +KI+SY QGFM+M+ A+ +NKW LN G IALMWRGGCIIRS FL NIK+AY     LS LL D++F++ I + Q SWR+VV+ A   G+P PA S+AL+FYDG RT  LPANLLQAQRD FGAH Y+LL     +HH NWTGT G+ +ASTY
Sbjct:    4 QADIALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFLANEAKDTKVIGADSLEDMVSKLKSPRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCDELAKLGLLFVGSGVSGGEEGARHGPSLMPGGHEAAWPLIQPIFQAICAKA-DGEPCCEWVGDGGAGHFVKMVHNGIEYGDMQLICEAYHIMQS-LGLSADQMADEFGKWNSAELDSFLIEITRDILKYKDGKG-YLLERIRDTAGQKGTGKWTAIAALQYGVPVTLIGEAVFSRCLSALKDERVQASSVLKGPSTKAQVANLTKFLDDIKHALYCAKIVSYAQGFMLMREAARENKWRLNYGGIALMWRGGCIIRSVFLGNIKDAYTSQPELSNLLLDDFFKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTAKLPANLLQAQRDYFGAHTYELLGQEGQFHHTNWTGTGGNVSASTY 479
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Fly
Match: Pgd (gene:FBgn0004654 transcript:FBtr0331410)

HSP 1 Score: 600.127 bits (1546), Expect = 0.000e+0
Identity = 302/479 (63.05%), Postives = 369/479 (77.04%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQNL+LNM  +GF VC +NRT+  + +FL N  K T VIGA SLE+ VSKLKSPRK+MLLVKAG AVDDFI  L+PLL++GD+IIDGGNSE+ D++RRC +LA+  +LFVGSGVSGGEEGAR+GPSLMPGG+  AW  IQPIFQAI AK  + EPCC+WVG  G+GHFVKMVHNGIEYGDMQLICEAYH+M+  L +  D++++ F  WN +EL+SFLIEIT  I K+++  G YLL +I D+AGQKGTGKWTAI AL  GVPVTLI E+VF+RCLS LK  R++AS      S+     N  +FL+D+K ALY +KI+SY QGFM+M+ A+ +NKW LN G IALMWRGGCIIRS FL NIK+AY     LS LL D++F++ I + Q SWR+VV+ A   G+P PA S+AL+FYDG RT  LPANLLQAQRD FGAH Y+LL     +HH NWTGT G+ +ASTY
Sbjct:    4 QADIALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFLANEAKDTKVIGADSLEDMVSKLKSPRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCDELAKLGLLFVGSGVSGGEEGARHGPSLMPGGHEAAWPLIQPIFQAICAKA-DGEPCCEWVGDGGAGHFVKMVHNGIEYGDMQLICEAYHIMQS-LGLSADQMADEFGKWNSAELDSFLIEITRDILKYKDGKG-YLLERIRDTAGQKGTGKWTAIAALQYGVPVTLIGEAVFSRCLSALKDERVQASSVLKGPSTKAQVANLTKFLDDIKHALYCAKIVSYAQGFMLMREAARENKWRLNYGGIALMWRGGCIIRSVFLGNIKDAYTSQPELSNLLLDDFFKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTAKLPANLLQAQRDYFGAHTYELLGQEGQFHHTNWTGTGGNVSASTY 479
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Zebrafish
Match: pgd (phosphogluconate dehydrogenase [Source:ZFIN;Acc:ZDB-GENE-040426-2807])

HSP 1 Score: 644.04 bits (1660), Expect = 0.000e+0
Identity = 314/479 (65.55%), Postives = 379/479 (79.12%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +  FLNN  K T VIGA SL++ VSKLK P +I+LLVKAGQAVDDFI+ L+PLL  GDIIIDGGNSE+ D+TRRC+ L EKN+LFVGSGVSGGE+GARYGPSLMPGG+ +AW H++ IFQ+IAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M +DE+++ F+ WNK+EL+SFLIEIT  I KF++ +G  LL +I DSAGQKGTGKWTAI+AL+ G PVTLI E+VFARCLS LK  R++ASK        KFTGNK +FL D++ ALYASKIISY QGFM+++ A+ +  WSLN G IALMWRGGCIIRS FL  IKEA++++  L  LL D +F + +  CQ SWR+VVST V +G+P P+F++AL+FYDG R E LPANLLQAQRD FGAH Y+LL NP  + H NWTG  G  ++S+Y
Sbjct:   31 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVHDFLNNEAKGTKVIGAESLKDMVSKLKKPCRIILLVKAGQAVDDFIDKLVPLLEPGDIIIDGGNSEYRDTTRRCKSLKEKNLLFVGSGVSGGEDGARYGPSLMPGGHKDAWPHLKDIFQSIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLCMNHDEMAQVFEQWNKTELDSFLIEITANILKFKDADGTNLLPKIRDSAGQKGTGKWTAISALEYGTPVTLIGEAVFARCLSSLKDERVQASKSLSGPQGVKFTGNKAQFLEDIRKALYASKIISYAQGFMLLRQAALEFGWSLNYGAIALMWRGGCIIRSVFLGKIKEAFDRNPELQSLLLDSFFSKAVQDCQDSWRRVVSTGVQQGIPMPSFTTALSFYDGYRHEMLPANLLQAQRDYFGAHTYELLSNPGTFIHTNWTGHGGKVSSSSY 509
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Zebrafish
Match: pgd (phosphogluconate dehydrogenase [Source:ZFIN;Acc:ZDB-GENE-040426-2807])

HSP 1 Score: 644.04 bits (1660), Expect = 0.000e+0
Identity = 314/479 (65.55%), Postives = 379/479 (79.12%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +  FLNN  K T VIGA SL++ VSKLK P +I+LLVKAGQAVDDFI+ L+PLL  GDIIIDGGNSE+ D+TRRC+ L EKN+LFVGSGVSGGE+GARYGPSLMPGG+ +AW H++ IFQ+IAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M +DE+++ F+ WNK+EL+SFLIEIT  I KF++ +G  LL +I DSAGQKGTGKWTAI+AL+ G PVTLI E+VFARCLS LK  R++ASK        KFTGNK +FL D++ ALYASKIISY QGFM+++ A+ +  WSLN G IALMWRGGCIIRS FL  IKEA++++  L  LL D +F + +  CQ SWR+VVST V +G+P P+F++AL+FYDG R E LPANLLQAQRD FGAH Y+LL NP  + H NWTG  G  ++S+Y
Sbjct:   31 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVHDFLNNEAKGTKVIGAESLKDMVSKLKKPCRIILLVKAGQAVDDFIDKLVPLLEPGDIIIDGGNSEYRDTTRRCKSLKEKNLLFVGSGVSGGEDGARYGPSLMPGGHKDAWPHLKDIFQSIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLCMNHDEMAQVFEQWNKTELDSFLIEITANILKFKDADGTNLLPKIRDSAGQKGTGKWTAISALEYGTPVTLIGEAVFARCLSSLKDERVQASKSLSGPQGVKFTGNKAQFLEDIRKALYASKIISYAQGFMLLRQAALEFGWSLNYGAIALMWRGGCIIRSVFLGKIKEAFDRNPELQSLLLDSFFSKAVQDCQDSWRRVVSTGVQQGIPMPSFTTALSFYDGYRHEMLPANLLQAQRDYFGAHTYELLSNPGTFIHTNWTGHGGKVSSSSY 509
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Xenopus
Match: PGD (phosphogluconate dehydrogenase [Source:NCBI gene;Acc:100491794])

HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0
Identity = 313/467 (67.02%), Postives = 375/467 (80.30%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWT 1453
            AD+ LIGLAVMGQNLVLNM   GF VC +NRT+  +D+FL N  K T VIGA SLEE VSKLK PR+IM+LVKAGQAVDDFINNL+P L  GDIIIDGGNSE+ DSTRRCR+L  KNILFVGSGVSGGE+GARYGPSLMPGG+ +AW HI+ IFQ+IAAKVEN EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L +  DE+++ F+ WNK+EL+SFLIEIT  I KF++ +G++LL +I D+AGQKGTGKWTAI+ALD GVPVTLI E+VFARCLS LK  R+EASK+      + F G+K  FL D++ ALYASKIISY QGF++ + A+ +  W+LN G IA+MWRGGCIIRS FL  IKEA++++  L  LL D +F+ E+ +CQ SWR+VVST V  G+P P F++AL+FYDG R E LPANL+QAQRD FGAH Y+ L NP  + H NWT
Sbjct:    4 ADIALIGLAVMGQNLVLNMNDHGFVVCAYNRTVSKVDQFLANEAKGTKVIGAHSLEEMVSKLKKPRRIMMLVKAGQAVDDFINNLVPYLEPGDIIIDGGNSEYRDSTRRCRELKAKNILFVGSGVSGGEDGARYGPSLMPGGDKQAWPHIKDIFQSIAAKVEN-EPCCDWVGEEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDILGIDQDEMAKAFEEWNKTELDSFLIEITADILKFKDTDGKHLLEKIQDTAGQKGTGKWTAISALDFGVPVTLIGEAVFARCLSSLKTERIEASKQLKGPKVNTFCGDKKAFLEDIRKALYASKIISYAQGFILFRQAAKEFGWNLNYGGIAMMWRGGCIIRSVFLGKIKEAFDRNPELQNLLLDNFFKSEMERCQESWRRVVSTGVQYGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYERLSNPGNFIHTNWT 469
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Xenopus
Match: PGD (phosphogluconate dehydrogenase [Source:NCBI gene;Acc:100491794])

HSP 1 Score: 637.491 bits (1643), Expect = 0.000e+0
Identity = 313/467 (67.02%), Postives = 375/467 (80.30%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWT 1453
            AD+ LIGLAVMGQNLVLNM   GF VC +NRT+  +D+FL N  K T VIGA SLEE VSKLK PR+IM+LVKAGQAVDDFINNL+P L  GDIIIDGGNSE+ DSTRRCR+L  KNILFVGSGVSGGE+GARYGPSLMPGG+ +AW HI+ IFQ+IAAKVEN EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L +  DE+++ F+ WNK+EL+SFLIEIT  I KF++ +G++LL +I D+AGQKGTGKWTAI+ALD GVPVTLI E+VFARCLS LK  R+EASK+      + F G+K  FL D++ ALYASKIISY QGF++ + A+ +  W+LN G IA+MWRGGCIIRS FL  IKEA++++  L  LL D +F+ E+ +CQ SWR+VVST V  G+P P F++AL+FYDG R E LPANL+QAQRD FGAH Y+ L NP  + H NWT
Sbjct:    6 ADIALIGLAVMGQNLVLNMNDHGFVVCAYNRTVSKVDQFLANEAKGTKVIGAHSLEEMVSKLKKPRRIMMLVKAGQAVDDFINNLVPYLEPGDIIIDGGNSEYRDSTRRCRELKAKNILFVGSGVSGGEDGARYGPSLMPGGDKQAWPHIKDIFQSIAAKVEN-EPCCDWVGEEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDILGIDQDEMAKAFEEWNKTELDSFLIEITADILKFKDTDGKHLLEKIQDTAGQKGTGKWTAISALDFGVPVTLIGEAVFARCLSSLKTERIEASKQLKGPKVNTFCGDKKAFLEDIRKALYASKIISYAQGFILFRQAAKEFGWNLNYGGIAMMWRGGCIIRSVFLGKIKEAFDRNPELQNLLLDNFFKSEMERCQESWRRVVSTGVQYGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYERLSNPGNFIHTNWT 471
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Xenopus
Match: PGD (phosphogluconate dehydrogenase [Source:NCBI gene;Acc:100491794])

HSP 1 Score: 630.172 bits (1624), Expect = 0.000e+0
Identity = 313/476 (65.76%), Postives = 375/476 (78.78%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNL---------IPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWT 1453
            AD+ LIGLAVMGQNLVLNM   GF VC +NRT+  +D+FL N  K T VIGA SLEE VSKLK PR+IM+LVKAGQAVDDFINNL         +P L  GDIIIDGGNSE+ DSTRRCR+L  KNILFVGSGVSGGE+GARYGPSLMPGG+ +AW HI+ IFQ+IAAKVEN EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L +  DE+++ F+ WNK+EL+SFLIEIT  I KF++ +G++LL +I D+AGQKGTGKWTAI+ALD GVPVTLI E+VFARCLS LK  R+EASK+      + F G+K  FL D++ ALYASKIISY QGF++ + A+ +  W+LN G IA+MWRGGCIIRS FL  IKEA++++  L  LL D +F+ E+ +CQ SWR+VVST V  G+P P F++AL+FYDG R E LPANL+QAQRD FGAH Y+ L NP  + H NWT
Sbjct:    7 ADIALIGLAVMGQNLVLNMNDHGFVVCAYNRTVSKVDQFLANEAKGTKVIGAHSLEEMVSKLKKPRRIMMLVKAGQAVDDFINNLSPVAKIGFTVPYLEPGDIIIDGGNSEYRDSTRRCRELKAKNILFVGSGVSGGEDGARYGPSLMPGGDKQAWPHIKDIFQSIAAKVEN-EPCCDWVGEEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDILGIDQDEMAKAFEEWNKTELDSFLIEITADILKFKDTDGKHLLEKIQDTAGQKGTGKWTAISALDFGVPVTLIGEAVFARCLSSLKTERIEASKQLKGPKVNTFCGDKKAFLEDIRKALYASKIISYAQGFILFRQAAKEFGWNLNYGGIAMMWRGGCIIRSVFLGKIKEAFDRNPELQNLLLDNFFKSEMERCQESWRRVVSTGVQYGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYERLSNPGNFIHTNWT 481
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Xenopus
Match: PGD (phosphogluconate dehydrogenase [Source:NCBI gene;Acc:100491794])

HSP 1 Score: 628.246 bits (1619), Expect = 0.000e+0
Identity = 313/478 (65.48%), Postives = 375/478 (78.45%), Query Frame = 2 
Query:   47 LNADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNL---------IPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWT 1453
              AD+ LIGLAVMGQNLVLNM   GF VC +NRT+  +D+FL N  K T VIGA SLEE VSKLK PR+IM+LVKAGQAVDDFINNL         +P L  GDIIIDGGNSE+ DSTRRCR+L  KNILFVGSGVSGGE+GARYGPSLMPGG+ +AW HI+ IFQ+IAAKVEN EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L +  DE+++ F+ WNK+EL+SFLIEIT  I KF++ +G++LL +I D+AGQKGTGKWTAI+ALD GVPVTLI E+VFARCLS LK  R+EASK+      + F G+K  FL D++ ALYASKIISY QGF++ + A+ +  W+LN G IA+MWRGGCIIRS FL  IKEA++++  L  LL D +F+ E+ +CQ SWR+VVST V  G+P P F++AL+FYDG R E LPANL+QAQRD FGAH Y+ L NP  + H NWT
Sbjct:   63 FQADIALIGLAVMGQNLVLNMNDHGFVVCAYNRTVSKVDQFLANEAKGTKVIGAHSLEEMVSKLKKPRRIMMLVKAGQAVDDFINNLSPVAKIGFTVPYLEPGDIIIDGGNSEYRDSTRRCRELKAKNILFVGSGVSGGEDGARYGPSLMPGGDKQAWPHIKDIFQSIAAKVEN-EPCCDWVGEEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDILGIDQDEMAKAFEEWNKTELDSFLIEITADILKFKDTDGKHLLEKIQDTAGQKGTGKWTAISALDFGVPVTLIGEAVFARCLSSLKTERIEASKQLKGPKVNTFCGDKKAFLEDIRKALYASKIISYAQGFILFRQAAKEFGWNLNYGGIAMMWRGGCIIRSVFLGKIKEAFDRNPELQNLLLDNFFKSEMERCQESWRRVVSTGVQYGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYERLSNPGNFIHTNWT 539
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Xenopus
Match: PGD (phosphogluconate dehydrogenase [Source:NCBI gene;Acc:100491794])

HSP 1 Score: 614.764 bits (1584), Expect = 0.000e+0
Identity = 305/466 (65.45%), Postives = 366/466 (78.54%), Query Frame = 2 
Query:   83 MGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNL---------IPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWT 1453
            MGQNLVLNM   GF VC +NRT+  +D+FL N  K T VIGA SLEE VSKLK PR+IM+LVKAGQAVDDFINNL         +P L  GDIIIDGGNSE+ DSTRRCR+L  KNILFVGSGVSGGE+GARYGPSLMPGG+ +AW HI+ IFQ+IAAKVEN EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L +  DE+++ F+ WNK+EL+SFLIEIT  I KF++ +G++LL +I D+AGQKGTGKWTAI+ALD GVPVTLI E+VFARCLS LK  R+EASK+      + F G+K  FL D++ ALYASKIISY QGF++ + A+ +  W+LN G IA+MWRGGCIIRS FL  IKEA++++  L  LL D +F+ E+ +CQ SWR+VVST V  G+P P F++AL+FYDG R E LPANL+QAQRD FGAH Y+ L NP  + H NWT
Sbjct:    1 MGQNLVLNMNDHGFVVCAYNRTVSKVDQFLANEAKGTKVIGAHSLEEMVSKLKKPRRIMMLVKAGQAVDDFINNLSPVAKIGFTVPYLEPGDIIIDGGNSEYRDSTRRCRELKAKNILFVGSGVSGGEDGARYGPSLMPGGDKQAWPHIKDIFQSIAAKVEN-EPCCDWVGEEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDILGIDQDEMAKAFEEWNKTELDSFLIEITADILKFKDTDGKHLLEKIQDTAGQKGTGKWTAISALDFGVPVTLIGEAVFARCLSSLKTERIEASKQLKGPKVNTFCGDKKAFLEDIRKALYASKIISYAQGFILFRQAAKEFGWNLNYGGIAMMWRGGCIIRSVFLGKIKEAFDRNPELQNLLLDNFFKSEMERCQESWRRVVSTGVQYGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYERLSNPGNFIHTNWT 465
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Mouse
Match: Pgd (phosphogluconate dehydrogenase [Source:MGI Symbol;Acc:MGI:97553])

HSP 1 Score: 624.009 bits (1608), Expect = 0.000e+0
Identity = 303/468 (64.74%), Postives = 371/468 (79.27%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWT 1453
             AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +D FL N  K T V+GA+SL++ VSKLK PR+++LLVKAGQAVDDFI  L+PLL++GDIIIDGGNSE+ D+TRRCR L  K ILFVGSGVSGGEEGARYGPSLMPGGN EAW HI+ IFQAIAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M ++E+++ F+ WNK+EL+SFLIEIT  I K+++ +G+ LL +I DSAGQKGTGKWTAI+AL+ G+PVTLI E+VFARCLS LK  R++AS++       +  G+K  FL D++ ALYASKIISY QGFM+++ A+ +  W+LN G IALMWRGGCIIRS FL  IK+A+E++  L  LL D++F+  +  CQ SWR+V+ST V  G+P P F++AL+FYDG R E LPANL+QAQRD FGAH Y+LL  P  + H NWT
Sbjct:    3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKDMVSKLKKPRRVILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKAIFQAIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMRHEEMAQAFEEWNKTELDSFLIEITANILKYRDTDGKELLPKIRDSAGQKGTGKWTAISALEYGMPVTLIGEAVFARCLSSLKEERVQASQKLKGPKVVQLEGSKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFERNPELQNLLLDDFFKSAVDNCQDSWRRVISTGVQAGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYELLTKPGEFIHTNWT 470
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. UniProt/SwissProt
Match: sp|P52209|6PGD_HUMAN (6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3)

HSP 1 Score: 642.884 bits (1657), Expect = 0.000e+0
Identity = 312/479 (65.14%), Postives = 378/479 (78.91%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +D FL N  K T V+GA+SL+E VSKLK PR+I+LLVKAGQAVDDFI  L+PLL++GDIIIDGGNSE+ D+TRRCR L  K ILFVGSGVSGGEEGARYGPSLMPGGN EAW HI+ IFQ IAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M  DE+++ F+ WNK+EL+SFLIEIT  I KFQ+ +G++LL +I DSAGQKGTGKWTAI+AL+ GVPVTLI E+VFARCLS LK  R++ASK+       +F G+K  FL D++ ALYASKIISY QGFM+++ A+ +  W+LN G IALMWRGGCIIRS FL  IK+A++++  L  LL D++F+  +  CQ SWR+ VST V  G+P P F++AL+FYDG R E LPA+L+QAQRD FGAH Y+LL  P  + H NWTG  G+ ++S+Y
Sbjct:    3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSY 481
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. UniProt/SwissProt
Match: sp|Q9DCD0|6PGD_MOUSE (6-phosphogluconate dehydrogenase, decarboxylating OS=Mus musculus OX=10090 GN=Pgd PE=1 SV=3)

HSP 1 Score: 624.009 bits (1608), Expect = 0.000e+0
Identity = 303/468 (64.74%), Postives = 371/468 (79.27%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWT 1453
             AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +D FL N  K T V+GA+SL++ VSKLK PR+++LLVKAGQAVDDFI  L+PLL++GDIIIDGGNSE+ D+TRRCR L  K ILFVGSGVSGGEEGARYGPSLMPGGN EAW HI+ IFQAIAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M ++E+++ F+ WNK+EL+SFLIEIT  I K+++ +G+ LL +I DSAGQKGTGKWTAI+AL+ G+PVTLI E+VFARCLS LK  R++AS++       +  G+K  FL D++ ALYASKIISY QGFM+++ A+ +  W+LN G IALMWRGGCIIRS FL  IK+A+E++  L  LL D++F+  +  CQ SWR+V+ST V  G+P P F++AL+FYDG R E LPANL+QAQRD FGAH Y+LL  P  + H NWT
Sbjct:    3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKDMVSKLKKPRRVILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKAIFQAIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMRHEEMAQAFEEWNKTELDSFLIEITANILKYRDTDGKELLPKIRDSAGQKGTGKWTAISALEYGMPVTLIGEAVFARCLSSLKEERVQASQKLKGPKVVQLEGSKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFERNPELQNLLLDDFFKSAVDNCQDSWRRVISTGVQAGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYELLTKPGEFIHTNWT 470
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. UniProt/SwissProt
Match: sp|P85968|6PGD_RAT (6-phosphogluconate dehydrogenase, decarboxylating OS=Rattus norvegicus OX=10116 GN=Pgd PE=1 SV=1)

HSP 1 Score: 623.624 bits (1607), Expect = 0.000e+0
Identity = 304/468 (64.96%), Postives = 370/468 (79.06%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWT 1453
             AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +D FL    K T VIGA+SL++ VSKLK PR+++LLVKAGQAVDDFI  L+PLL++GDIIIDGGNSE+ D+TRRC+ L  K ILFVGSGVSGGEEGARYGPSLMPGGN EAW HI+ IFQAIAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M ++E+++ F+ WNK+EL+SFLIEIT  I KFQ+ +G+ LL +I DSAGQKGTGKWTAI+AL+ G+PVTLI E+VFARCLS LK  R++AS++       +  G+K  FL D++ ALYASKIISY QGFM+++ A+ +  W+LN G IALMWRGGCIIRS FL  IK+A+E++  L  LL D++F+  +  CQ SWR+V+ST V  G+P P F++AL+FYDG R E LPANL+QAQRD FGAH Y+LL  P  + H NWT
Sbjct:    3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLAKEAKGTKVIGAKSLKDMVSKLKKPRRVILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCQDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQAIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMRHEEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKELLPKIRDSAGQKGTGKWTAISALEYGMPVTLIGEAVFARCLSSLKEERVQASRKLKGPKMVQLEGSKQAFLEDVRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFERNPELQNLLLDDFFKSAVDDCQDSWRRVISTGVQAGIPMPCFTTALSFYDGYRHEMLPANLIQAQRDYFGAHTYELLSKPGEFIHTNWT 470
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. UniProt/SwissProt
Match: sp|P00349|6PGD_SHEEP (6-phosphogluconate dehydrogenase, decarboxylating OS=Ovis aries OX=9940 GN=PGD PE=1 SV=4)

HSP 1 Score: 601.282 bits (1549), Expect = 0.000e+0
Identity = 303/468 (64.74%), Postives = 368/468 (78.63%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWT 1453
             AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +D FL N  K T V+GA SLEE VSKLK PR+I+LLVKAGQAVD+FI  L+PLL+ GDIIIDGGNSE+ D+ RRCR L +K ILFVGSGVSGGE+GARYGPSLMPGGN EAW HI+ IFQ IAAKV   EPCCDWVG +G+GHFVKMVHNGIEYGDMQLICEAYHLM+D L +G+ E+++ F+ WNK+EL+SFLIEIT  I KFQ+ +G++LL +I DSAGQKGTGKWTAI+AL+ GVPVTLI E+VFARCLS LK  R++ASK+     +  F G+K  FL D++ ALYASKIISY QGFM+++ A+ +  W+LN G IALMWRGGCIIRS FL  IK+A++++  L  LL D++F+  +  CQ SWR+ +ST V  G+P P F++AL+FYDG R   LPANL+QAQRD FGAH Y+LL  P  + H NWT
Sbjct:    3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVLGAHSLEEMVSKLKKPRRIILLVKAGQAVDNFIEKLVPLLDIGDIIIDGGNSEYRDTMRRCRDLKDKGILFVGSGVSGGEDGARYGPSLMPGGNKEAWPHIKAIFQGIAAKVGTGEPCCDWVGDDGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGLGHKEMAKAFEEWNKTELDSFLIEITASILKFQDADGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQNIPFEGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPGLQNLLLDDFFKSAVENCQDSWRRAISTGVQAGIPMPCFTTALSFYDGYRHAMLPANLIQAQRDYFGAHTYELLAKPGQFIHTNWT 470
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. UniProt/SwissProt
Match: sp|P41572|6PGD_DROME (6-phosphogluconate dehydrogenase, decarboxylating OS=Drosophila melanogaster OX=7227 GN=Pgd PE=2 SV=1)

HSP 1 Score: 600.512 bits (1547), Expect = 0.000e+0
Identity = 302/479 (63.05%), Postives = 369/479 (77.04%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQNL+LNM  +GF VC +NRT+  + +FL N  K T VIGA SLE+ VSKLKSPRK+MLLVKAG AVDDFI  L+PLL++GD+IIDGGNSE+ D++RRC +LA+  +LFVGSGVSGGEEGAR+GPSLMPGG+  AW  IQPIFQAI AK  + EPCC+WVG  G+GHFVKMVHNGIEYGDMQLICEAYH+M+  L +  D++++ F  WN +EL+SFLIEIT  I K+++  G YLL +I D+AGQKGTGKWTAI AL  GVPVTLI E+VF+RCLS LK  R++AS      S+     N  +FL+D+K ALY +KI+SY QGFM+M+ A+ +NKW LN G IALMWRGGCIIRS FL NIK+AY     LS LL D++F++ I + Q SWR+VV+ A   G+P PA S+AL+FYDG RT  LPANLLQAQRD FGAH Y+LL     +HH NWTGT G+ +ASTY
Sbjct:    4 QADIALIGLAVMGQNLILNMDEKGFVVCAYNRTVAKVKEFLANEAKDTKVIGADSLEDMVSKLKSPRKVMLLVKAGSAVDDFIQQLVPLLSAGDVIIDGGNSEYQDTSRRCDELAKLGLLFVGSGVSGGEEGARHGPSLMPGGHEAAWPLIQPIFQAICAKA-DGEPCCEWVGDGGAGHFVKMVHNGIEYGDMQLICEAYHIMKS-LGLSADQMADEFGKWNSAELDSFLIEITRDILKYKDGKG-YLLERIRDTAGQKGTGKWTAIAALQYGVPVTLIGEAVFSRCLSALKDERVQASSVLKGPSTKAQVANLTKFLDDIKHALYCAKIVSYAQGFMLMREAARENKWRLNYGGIALMWRGGCIIRSVFLGNIKDAYTSQPELSNLLLDDFFKKAIERGQDSWREVVANAFRWGIPVPALSTALSFYDGYRTAKLPANLLQAQRDYFGAHTYELLGQEGQFHHTNWTGTGGNVSASTY 479
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. TrEMBL
Match: A0A1S3H7B5 (6-phosphogluconate dehydrogenase, decarboxylating OS=Lingula unguis OX=7574 GN=LOC106152373 PE=3 SV=1)

HSP 1 Score: 654.825 bits (1688), Expect = 0.000e+0
Identity = 323/478 (67.57%), Postives = 378/478 (79.08%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
            AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +D FL N  K T VIGA+SLEE V  LK PR++M+LVKAG AVD FI  L+PLL SGDIIIDGGNSE+ D+ RRCR L EK ILFVGSGVSGGE+GARYGPSLMPGG  EAW HI+PIFQ+IAAK  N EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M ++E++++FD WNK ELESFLIEIT  I  F++E GE L+ +I DSAGQKGTGKWTAI+AL+ G+PVTLI ESVFARCLS LK  R+ ASK     +S K+TG+K EF+N ++ ALYASKIISY QGFM+M+ A+    W LN G IALMWRGGCIIRS FL NIKEA++K+ +L  LL D++F+  I  CQ SWRKVVSTAV  G+PTP FS+ALAFYDG R+  +PANL+QAQRD FGAH YQLL  P  Y H NWTG  G+ +++TY
Sbjct:    6 ADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVEKVDTFLANEAKGTKVIGAKSLEEMVKTLKKPRRVMMLVKAGSAVDAFIEKLVPLLESGDIIIDGGNSEYTDTNRRCRSLKEKGILFVGSGVSGGEDGARYGPSLMPGGAPEAWPHIKPIFQSIAAKT-NGEPCCDWVGEEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMSHNEMAQSFDDWNKGELESFLIEITRDIMNFRDERGEVLVEKILDSAGQKGTGKWTAISALEYGMPVTLIGESVFARCLSSLKEERVAASKVLKGPASTKYTGDKREFVNHIRKALYASKIISYAQGFMLMREAAKNFGWKLNFGGIALMWRGGCIIRSVFLSNIKEAFDKNPDLVNLLLDDFFKTAIHNCQDSWRKVVSTAVTLGIPTPCFSTALAFYDGYRSATVPANLIQAQRDYFGAHTYQLLSTPGKYVHTNWTGHGGNVSSTTY 482
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. TrEMBL
Match: Q6TNR8 (6-phosphogluconate dehydrogenase, decarboxylating OS=Danio rerio OX=7955 GN=pgd PE=2 SV=1)

HSP 1 Score: 649.818 bits (1675), Expect = 0.000e+0
Identity = 316/479 (65.97%), Postives = 381/479 (79.54%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +  FLNN  K T VIGA SLE+ VSKLK PR+I+LLVKAGQAVDDFI+ L+PLL  GDIIIDGGNSE+ D+TRRC+ L EKN+LFVGSGVSGGE+GARYGPSLMPGG+ +AW H++ IFQ+IAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M +DE+++ F+ WNK+EL+SFLIEIT  I KF++ +G  LL +I DSAGQKGTGKWTAI+AL+ G PVTLI E+VFARCLS LK  R++ASK        KFTGNK++FL D++ ALYASKIISY QGFM+++ A+ +  WSLN G IALMWRGGCIIRS FL  IKEA++++  L  LL D +F + +  CQ SWR+VVST V +G+P P+F++AL+FYDG R E LPANLLQAQRD FGAH Y+LL NP  + H NWTG  G  ++S+Y
Sbjct:    3 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVHDFLNNEAKGTKVIGAESLEDMVSKLKKPRRIILLVKAGQAVDDFIDKLVPLLEPGDIIIDGGNSEYRDTTRRCKSLKEKNLLFVGSGVSGGEDGARYGPSLMPGGHKDAWPHLKDIFQSIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLCMNHDEMAQVFEQWNKTELDSFLIEITANILKFKDADGTNLLPKIRDSAGQKGTGKWTAISALEYGTPVTLIGEAVFARCLSSLKDERVQASKSLSGPQGVKFTGNKEQFLEDIRKALYASKIISYAQGFMLLRQAALEFGWSLNYGAIALMWRGGCIIRSVFLGKIKEAFDRNPELQSLLLDSFFSKAVQDCQDSWRRVVSTGVQQGIPMPSFTTALSFYDGYRHEMLPANLLQAQRDYFGAHTYELLSNPGTFIHTNWTGHGGKVSSSSY 481
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. TrEMBL
Match: A0A091R712 (6-phosphogluconate dehydrogenase, decarboxylating (Fragment) OS=Mesitornis unicolor OX=54374 GN=N332_09397 PE=3 SV=1)

HSP 1 Score: 649.047 bits (1673), Expect = 0.000e+0
Identity = 318/478 (66.53%), Postives = 381/478 (79.71%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
            AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +D FL N  K T VIGA SLEE VSKLK PR+I+LLVKAG AVDDFIN L+PLL +GDIIIDGGNSE+ D+TRRC++L EK ILFVGSGVSGGEEGARYGPSLMPGG  EAW HI+ IFQ++AAKV + EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M +DE+SE F  WNK+EL+SFLIEIT  I KF++ +G+YLL +I DSAGQKGTGKWTAI+AL+ GVPVTLI E+VFARCLS LK  R++ASK      +  F GNK  FL D++ ALYASKIISY QGFM+++ A+ +  W+LN G IALMWRGGCIIRS FL  IK+A++++  L  LL DE+F++ +  CQ SWR+V+ST V  G+P P F++AL+FYDG R + LPANL+QAQRD FGAH Y+LL NP A+ H NWTG  G+ ++S Y
Sbjct:    3 ADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVIGAHSLEEMVSKLKKPRRIILLVKAGSAVDDFINKLVPLLETGDIIIDGGNSEYRDTTRRCKELREKGILFVGSGVSGGEEGARYGPSLMPGGAKEAWPHIKTIFQSVAAKVGSGEPCCDWVGEEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMEHDEMSEVFQEWNKTELDSFLIEITANILKFKDNDGKYLLPKIKDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERVQASKLLDGPKNTHFGGNKKAFLEDIRKALYASKIISYAQGFMLLRQAAKEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPGLQNLLLDEFFKKAVENCQDSWRRVISTGVQIGIPMPCFTTALSFYDGYRHQVLPANLIQAQRDYFGAHTYELLSNPGAFVHTNWTGHGGNVSSSAY 480
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. TrEMBL
Match: A0A093QYB3 (6-phosphogluconate dehydrogenase, decarboxylating (Fragment) OS=Phalacrocorax carbo OX=9209 GN=N336_10584 PE=3 SV=1)

HSP 1 Score: 648.662 bits (1672), Expect = 0.000e+0
Identity = 318/478 (66.53%), Postives = 380/478 (79.50%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
            AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +D FL N  K T VIGA SLEE VSKLK PR+I+LLVKAG AVDDFIN L+PLL +GDIIIDGGNSE+ D+TRRC++L EK ILFVGSGVSGGEEGARYGPSLMPGG  EAW HI+ IFQ+IAAKV + EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D + M +DE+SE F  WNK+EL+SFLIEIT  I KF++ +G+YLL +I DSAGQKGTGKWTAI+AL+ GVPVTLI E+VFARCLS LK  R++ASK      + KF+GNK  FL D++ ALYASKIISY QGFM+++ A+ +  W+LN G IALMWRGGCIIRS FL  IK+A++++  L  LL D++F+  +  CQ SWR+V+ST V  G+P P F++AL+FYDG R E LPANL+QAQRD FGAH Y+LL  P  + H NWTG  GS ++S Y
Sbjct:    3 ADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVIGAHSLEEMVSKLKKPRRIILLVKAGTAVDDFINKLVPLLETGDIIIDGGNSEYRDTTRRCKELQEKGILFVGSGVSGGEEGARYGPSLMPGGAKEAWPHIKTIFQSIAAKVGSGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVVGMEHDEMSEVFQEWNKTELDSFLIEITANILKFKDSDGKYLLPKIKDSAGQKGTGKWTAISALEFGVPVTLIGEAVFARCLSSLKDERVQASKLLGGPKATKFSGNKKAFLEDIRKALYASKIISYAQGFMLLRQAAKEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKTAVENCQDSWRRVISTGVQIGIPMPCFTTALSFYDGYRHEVLPANLIQAQRDYFGAHTYELLSKPGVFIHTNWTGHGGSVSSSAY 480
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. TrEMBL
Match: A0A553RNG1 (6-phosphogluconate dehydrogenase, decarboxylating OS=Danionella translucida OX=623744 GN=DNTS_009728 PE=3 SV=1)

HSP 1 Score: 648.277 bits (1671), Expect = 0.000e+0
Identity = 318/479 (66.39%), Postives = 381/479 (79.54%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQNL+LNM   GF VC FNRT+  +  FLNN  K T VIGA SLE+ VSKLK PR+I+LLVKAGQAVDDFI+ L+PLL+SGDIIIDGGNSE+ D+TRRC+ L EK +LFVGSGVSGGEEGARYGPSLMPGG+ EAW HI+ IFQ+IAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M +DE+++ F+ WNK+EL+SFLIEIT  I KF++ +G +LL +I DSAGQKGTGKWTAI+AL+ G PVTLI E+VFARCLS LK  R+ AS+        KF+GNK +FL D+K ALYASKIISY QGFM+++ A+ +  WSLN G IALMWRGGCIIRS FL  IKEA++++  L  LL D++F + +  CQ SWR+VVST V +G+P P F++AL+FYDG R E LPANLLQAQRD FGAH Y+LL NP  + H NWTG  G  ++S+Y
Sbjct:   31 QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVHDFLNNEAKGTKVIGAESLEDMVSKLKKPRRIILLVKAGQAVDDFIDKLVPLLDSGDIIIDGGNSEYRDTTRRCKSLQEKKLLFVGSGVSGGEEGARYGPSLMPGGHKEAWPHIKDIFQSIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLCMDHDEMAQVFEEWNKTELDSFLIEITANILKFKDADGTHLLPKIRDSAGQKGTGKWTAISALEYGTPVTLIGEAVFARCLSSLKEERVNASRSLAGPQRVKFSGNKAQFLEDIKKALYASKIISYAQGFMLLRQAALEFGWSLNYGAIALMWRGGCIIRSVFLGKIKEAFDQNPELQNLLLDDFFCKAVQDCQESWRRVVSTGVQQGIPMPCFTTALSFYDGYRHEMLPANLLQAQRDYFGAHTYELLSNPGKFIHTNWTGHGGKVSSSSY 509
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Cavefish
Match: pgd (phosphogluconate dehydrogenase [Source:NCBI gene;Acc:103026797])

HSP 1 Score: 643.269 bits (1658), Expect = 0.000e+0
Identity = 315/479 (65.76%), Postives = 380/479 (79.33%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQNL+LNM   GF VC +NRT+  +  FL N  K T VIGA SLE+ VSKLK+PR+I+LLVKAGQAVDDFI+ L+PLL  GDIIIDGGNSE+ D+TRRC+ L  K +LFVGSGVSGGEEGARYGPSLMPGG+ EAW HI+ IFQ+IAAKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M +DE+++ FD WNK+EL+SFLIEIT  I KF++ +G++LL +I DSAGQKGTGKWTAI+AL+ GVPVTLI E+VFARCLS LK  R+ ASK        KFTG+K +FL D++ ALYASKIISY QGFM+++ A+++  WSLN G IALMWRGGCIIRS FL  IKEA+++D NL  LL D++F   +  CQ SWR+VVS  V  G+P P+F++AL+FYDG R   LPANLLQAQRD FGAH Y+LL NP  + H NWTG  G+ ++++Y
Sbjct:    3 QADIALIGLAVMGQNLILNMNDHGFVVCAYNRTVSKVHDFLKNEAKGTKVIGAESLEDMVSKLKTPRRIVLLVKAGQAVDDFIDKLVPLLQPGDIIIDGGNSEYRDTTRRCQSLKAKGLLFVGSGVSGGEEGARYGPSLMPGGHKEAWPHIKDIFQSIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMDHDEMAQAFDQWNKTELDSFLIEITANILKFKDSDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKEERVLASKSLTGPQGAKFTGDKAKFLEDIRKALYASKIISYAQGFMLLRQAANEFGWSLNYGGIALMWRGGCIIRSVFLGKIKEAFDRDSNLQNLLLDDFFSNAVQDCQASWRRVVSKGVELGIPMPSFTTALSFYDGYRHAMLPANLLQAQRDYFGAHTYELLSNPGQFIHTNWTGHGGNVSSTSY 481
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Yeast
Match: GND2 (6-phosphogluconate dehydrogenase (decarboxylating); catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone; GND2 has a paralog, GND1, that arose from the whole genome duplication [Source:SGD;Acc:S000003488])

HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0
Identity = 289/490 (58.98%), Postives = 358/490 (73.06%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASK-----RFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYH-------HCNWTGTSGSAAASTY 1486
             DLGL+GLAVMGQNL+LN A  GF V  +NRT   +D+FL N  K  ++IGA S+E+ V+KLK PRKIMLL+KAG  VD  I  L+P L+ GDIIIDGGNS F D+ RR  +L ++ ILFVGSGVSGGE+GAR+GPSLMPGG+ EAW HI+ IFQ+IAAK  N EPCC+WVG  GSGH+VKMVHNGIEYGDMQLICEAY +M+      + EISE FD WN   L+SFLIEIT  I KF + +G+ L+ +I D+AGQKGTGKWTAINALDLG+PVTLI E+VFARCLS +K  R  ASK       P ++ H    ++++F+ DL+ ALYASKIISY QGFM+++ A+    W LN   IALMWRGGCIIRS FL  I +AY  D +L  LLF+E+F   + K Q+ WR+ ++ A   G+PTPAFS+ALAFYDG R+E LPANLLQAQRD FGAH +++L   ++ H       H NWTG  G+ ++STY
Sbjct:    6 GDLGLVGLAVMGQNLILNAADHGFTVVAYNRTQSKVDRFLANEAKGKSIIGATSIEDLVAKLKKPRKIMLLIKAGAPVDTLIKELVPHLDKGDIIIDGGNSHFPDTNRRYEELTKQGILFVGSGVSGGEDGARFGPSLMPGGSAEAWPHIKNIFQSIAAK-SNGEPCCEWVGPAGSGHYVKMVHNGIEYGDMQLICEAYDIMKRIGRFTDKEISEVFDKWNTGVLDSFLIEITRDILKFDDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSAIKDERKRASKLLAGPTVPKDAIH----DREQFVYDLEQALYASKIISYAQGFMLIREAARSYGWKLNNPAIALMWRGGCIIRSVFLAEITKAYRDDPDLENLLFNEFFASAVTKAQSGWRRTIALAATYGIPTPAFSTALAFYDGYRSERLPANLLQAQRDYFGAHTFRILPECASAHLPVDKDIHINWTGHGGNISSSTY 490
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Yeast
Match: GND1 (6-phosphogluconate dehydrogenase (decarboxylating); catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress; GND1 has a paralog, GND2, that arose from the whole genome duplication [Source:SGD;Acc:S000001226])

HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0
Identity = 289/488 (59.22%), Postives = 362/488 (74.18%), Query Frame = 2 
Query:   47 LNADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHK-FTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYH-------HCNWTGTSGSAAASTY 1486
            ++AD GLIGLAVMGQNL+LN A  GF VC +NRT   +D FL N  K  ++IGA S+E+F+SKLK PRK+MLLVKAG  VD  IN ++PLL  GDIIIDGGNS F DS RR  +L +K ILFVGSGVSGGEEGARYGPSLMPGG+ EAW HI+ IFQ+I+AK  + EPCC+WVG  G+GH+VKMVHNGIEYGDMQLICEAY +M+      + EIS+ F  WN   L+SFL+EIT  I KF + +G+ L+ +I D+AGQKGTGKWTAINALDLG+PVTLI E+VFARCLS LK  R+ ASK  P     K    ++++F++DL+ ALYASKIISY QGFM+++ A+    W LN   IALMWRGGCIIRS FL  I +AY ++ +L  LLF+++F   + K Q+ WRK ++ A   G+PTPAFS+AL+FYDG R+E LPANLLQAQRD FGAH +++L   ++ +       H NWTG  G+ ++STY
Sbjct:    1 MSADFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDFISKLKRPRKVMLLVKAGAPVDALINQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGILFVGSGVSGGEEGARYGPSLMPGGSEEAWPHIKNIFQSISAK-SDGEPCCEWVGPAGAGHYVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNNGVLDSFLVEITRDILKFDDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSALKNERIRASKVLPGPEVPKDAVKDREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLNNPAIALMWRGGCIIRSVFLGQITKAYREEPDLENLLFNKFFADAVTKAQSGWRKSIALATTYGIPTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPECASDNLPVDKDIHINWTGHGGNVSSSTY 487
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Yeast
Match: YHR182C-A_mRNA (Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; almost completely overlaps ORF GND1/YHR183W [Source:SGD;Acc:S000028784])

HSP 1 Score: 58.5362 bits (140), Expect = 9.795e-11
Identity = 42/157 (26.75%), Postives = 78/157 (49.68%), Query Frame = -3 
Query:   35 MLPSFDVSTGHETRSISCSFFASTYTRSNK*NILFS*LSTSSRRVIKFRISSIYYYVTRI*KRYQIVNKIINCLARLYK*HYFPGRLQFTDEFLQRPCTY--YICSFW*VV*KFIHHQQSSIENTNPKSLTSHIQHKILPHYCKSN*PKICIKNHFL 499
            M PSF  +T H+  +++ +F  +  TR+N+ N L      +S R+ + R+++I   +T   K   +V++ +N      + H     LQF DE      T   +  SF  +  + +    SS+ +TN +++ S +Q +IL H  ++N  +  I  HF+
Sbjct:    1 MWPSFFRTTWHQRWTVTGTFLTTGDTRTNEKNTLLLQFFVTSIRIWEVRVTTIDDNITLFQKWDDLVDQSVNWSTSFNQKHDLSRSLQFGDEIFNGSSTDDRFALSF--IGQEMVDLGLSSVVSTNSETVVSSVQDQILTHDGQTN--QTEISRHFI 153
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Nematostella
Match: EDO35313 (6-phosphogluconate dehydrogenase, decarboxylating [Source:UniProtKB/TrEMBL;Acc:A7SLT6])

HSP 1 Score: 639.802 bits (1649), Expect = 0.000e+0
Identity = 312/479 (65.14%), Postives = 379/479 (79.12%), Query Frame = 2 
Query:   50 NADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
             AD+ LIGLAVMGQN++LNM   G+ VC  NRT+  +D+FL N  K T ++GA SL+E VSKLK PR++M+LVKAG AVD FI++L+PLL SGDIIIDGGNSE+ DS RRC+ L E+ +LFVGSGVSGGEEGARYGPSLMPGG+ +AW HI+PIFQAIAAK   N+PCCDWVG +GSGHFVKMVHNGIEYGDMQL CEAYHLM+D L M +DEIS+ FD WNK EL+SFLIEIT  I  +++ +G  L+ +I DSAGQKGTGKWTAI+AL+ G+PVTLI ESVFARCLS L+  R+ AS      +S KFTG+K EF+  ++ ALYASKI+SY QGFM+M+ A+    W LN G IALMWRGGCIIRSRFL NIK+A+ K+ NL  LL D++F+  I KCQ SWRK ++TAV  G+PTPAFS+ALAFYDG R+  LPANL+QAQRD FGAH Y+LL NP  + H NWTG  G+ +++TY
Sbjct:    5 TADIALIGLAVMGQNIILNMNDHGYVVCAHNRTVEKVDRFLANEAKGTRIVGAHSLQEMVSKLKKPRRVMILVKAGSAVDAFIDHLVPLLESGDIIIDGGNSEYKDSMRRCKALEERGLLFVGSGVSGGEEGARYGPSLMPGGSEKAWPHIKPIFQAIAAKA-GNDPCCDWVGGDGSGHFVKMVHNGIEYGDMQLCCEAYHLMKDALGMTSDEISQVFDEWNKGELDSFLIEITKNIMAYKDADGSPLVEKIRDSAGQKGTGKWTAISALEYGMPVTLIGESVFARCLSSLQAERVHASTHLKGPASTKFTGDKKEFVEHIRKALYASKIVSYAQGFMLMREAAKVFNWKLNYGGIALMWRGGCIIRSRFLGNIKDAFNKNPNLDNLLLDDFFKDAIHKCQDSWRKTIATAVTLGIPTPAFSTALAFYDGYRSARLPANLIQAQRDYFGAHTYELLSNPGHFIHTNWTGKGGNVSSTTY 482
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Nematostella
Match: EDO28780 (6-phosphogluconate dehydrogenase, decarboxylating [Source:UniProtKB/TrEMBL;Acc:A7T5I4])

HSP 1 Score: 448.743 bits (1153), Expect = 6.088e-156
Identity = 223/334 (66.77%), Postives = 267/334 (79.94%), Query Frame = 2 
Query:  374 RRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQ 1375
            RRC+ L E+ +LFVGSGVSGGEEGARYGPSLMPGG+ +AW HI+PIFQAIAAK   N+PCCDWVG +GSGHFVKMVHNGIEYGDMQL CEAYHLM+D L M +DEIS+ FD WNK EL+SFLIEIT  I  +++ +G  L+ +I DSAGQKGTGKWTAI+AL+ G+PVTLI ESVFARCLS L+  R+ AS      +S KFTG+K EF+  ++ ALYASKI+SY QGFM+M+ A+    W LN G IALMWRGGCIIRSRFL NIK+A+ K+ NL  LL D++F+  I KCQ SWRK ++TAV  G+PTPAFS+ALAFYDG R+  LPANL+Q
Sbjct:    2 RRCKALEERGLLFVGSGVSGGEEGARYGPSLMPGGSEKAWPHIKPIFQAIAAKA-GNDPCCDWVGGDGSGHFVKMVHNGIEYGDMQLCCEAYHLMKDALGMTSDEISQVFDEWNKGELDSFLIEITKNIMAYKDADGSPLVEKIRDSAGQKGTGKWTAISALEYGMPVTLIGESVFARCLSSLQAERVHASTHLKGPASTKFTGDKKEFVEHIRKALYASKIVSYAQGFMLMREAAKVFNWKLNYGGIALMWRGGCIIRSRFLGNIKDAFNKNPNLDNLLLDDFFKDAIHKCQDSWRKTIATAVTLGIPTPAFSTALAFYDGYRSARLPANLIQ 334
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Medaka
Match: pgd (phosphogluconate dehydrogenase [Source:NCBI gene;Acc:101173937])

HSP 1 Score: 640.188 bits (1650), Expect = 0.000e+0
Identity = 308/478 (64.44%), Postives = 379/478 (79.29%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
            AD+ LIGLAVMGQNL++NM   GF VC +NRT+  +  FLNN  K + V+GA SLE+ VSKLK PR+I+LLVKAGQAVDDFI+ L+PLL++GDIIIDGGNSE+ D+TRRC+ L EK +LFVGSGVSGGEEGARYGPSLMPGG+ EAW HI+ IFQ+I+AKV   EPCCDWVG EG+GHFVKMVHNGIEYGDMQLICEAYHLM+D L M +DE+ + F++WNK+EL+SFLIEIT  I K+++ +G++LL +I DSAGQKGTGKWTAI+AL+ G PVTLI E+VFARCLS LK  R+EAS+        KF+GNK  FL D++ ALYASKIISY QGFM+++ A+ +  WSLN G IALMWRGGCIIRS FL  IKEA+++D +L  LL D +F + +  CQ SWR+ V T V  G+P P F++AL+FYDG R + LPANLLQAQRD FGAH Y+LL  P  + H NWTG  G+ ++S+Y
Sbjct:    4 ADIALIGLAVMGQNLIMNMNDHGFVVCAYNRTVSKVHDFLNNEAKGSKVVGAESLEDMVSKLKKPRRIILLVKAGQAVDDFIDKLVPLLDAGDIIIDGGNSEYRDTTRRCQSLKEKGLLFVGSGVSGGEEGARYGPSLMPGGHKEAWPHIKDIFQSISAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMDHDEMGQAFESWNKTELDSFLIEITANILKYRDSDGKHLLPKIRDSAGQKGTGKWTAISALEYGTPVTLIGEAVFARCLSSLKEERVEASRSLSGPQGVKFSGNKASFLEDIRKALYASKIISYAQGFMLLRQAAKEFSWSLNYGAIALMWRGGCIIRSVFLGKIKEAFDRDGDLQNLLLDHFFSKAVQDCQESWRRTVGTGVQHGIPMPCFTTALSFYDGYRHDMLPANLLQAQRDYFGAHTYELLSKPGHFIHTNWTGHGGNVSSSSY 481
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Planmine SMEST
Match: SMESG000005726.1 (SMESG000005726.1)

HSP 1 Score: 962.214 bits (2486), Expect = 0.000e+0
Identity = 479/501 (95.61%), Postives = 483/501 (96.41%), Query Frame = 2 
Query:   41 MILNADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQ-----------------TSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTYTC 1492
            MILNAD+GLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPK TNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFVGSGVSGGEEGARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVR+EASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMK+ASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKC+                 TSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTYTC
Sbjct:    1 MILNADIGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKNTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFVGSGVSGGEEGARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRVEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKSASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCEVTIDEEIKYNSIELFIKTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTYTC 501
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Planmine SMEST
Match: SMESG000005726.1 (SMESG000005726.1)

HSP 1 Score: 875.93 bits (2262), Expect = 0.000e+0
Identity = 440/463 (95.03%), Postives = 444/463 (95.90%), Query Frame = 2 
Query:   41 MILNADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQ-----------------TSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQA 1378
            MILNAD+GLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPK TNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFVGSGVSGGEEGARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVR+EASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMK+ASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKC+                 TSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQ 
Sbjct:    1 MILNADIGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKNTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFVGSGVSGGEEGARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRVEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKSASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCEVTIDEEIKYNSIELFIKTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQV 463
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Planmine SMEST
Match: SMESG000005722.1 (SMESG000005722.1)

HSP 1 Score: 782.711 bits (2020), Expect = 0.000e+0
Identity = 390/410 (95.12%), Postives = 392/410 (95.61%), Query Frame = 2 
Query:  308 IPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQ-----------------TSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
            IPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFVGSGVSGGEEGARYGPSLMPGGNIEAWKHIQPIFQAIAAKVEN EPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTG+KDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKC+                 TSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY
Sbjct:   29 IPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFVGSGVSGGEEGARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENIEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGSKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCEVTIDEEIKYNSIELFIKTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 438
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Planmine SMEST
Match: SMESG000005724.1 (SMESG000005724.1)

HSP 1 Score: 748.814 bits (1932), Expect = 0.000e+0
Identity = 359/478 (75.10%), Postives = 408/478 (85.36%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
            +D G+IGL VMGQN  LN+   G+ VCVFNR L ++D FLNN    +N+ G+++ EEFV KL  PRKIMLL++AG  VDD I  L+PLL+SGDIIIDGGNSEFNDSTRRCRQLAEKNILFVGSGVSGGEEGARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRD LHMGNDEIS TF+ WNK ELES+LIEIT+++T +Q+ENG YLL++IYD AGQKGTGKWTAI+ LD GVPVTLIAESVF+R LS LK +R++ SK+FPS+ + +FT NK+EFL  +K ALYASKIISYTQGFMMMK  S+  KW LNLGKIA+ WRGGC+IRSRFL NIKEAY+ D NLS+L+ DE+F+ E+LKCQ SWRKVVS A L G+P PAFSSAL FYDGLRTE LPANLLQAQRD+FGAHQYQLL N  A+HH NWTG  G+A A+ Y
Sbjct:    4 SDFGMIGLGVMGQNFALNLNDHGYKVCVFNRELDILDHFLNNEASNSNITGSKTFEEFVDKLTLPRKIMLLIRAGTPVDDVIEKLVPLLSSGDIIIDGGNSEFNDSTRRCRQLAEKNILFVGSGVSGGEEGARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDLLHMGNDEISATFEEWNKGELESYLIEITSLVTNYQSENGSYLLDEIYDCAGQKGTGKWTAISGLDCGVPVTLIAESVFSRYLSTLKALRLKVSKQFPSDCAFEFTENKNEFLKSIKQALYASKIISYTQGFMMMKNTSESYKWDLNLGKIAMTWRGGCVIRSRFLSNIKEAYDTDCNLSILILDEFFRNEVLKCQRSWRKVVSIAALYGIPIPAFSSALNFYDGLRTEKLPANLLQAQRDVFGAHQYQLLSNTEAFHHTNWTGNGGTATATKY 481
[Close]
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Planmine SMEST
Match: SMESG000005721.1 (SMESG000005721.1)

HSP 1 Score: 741.88 bits (1914), Expect = 0.000e+0
Identity = 365/478 (76.36%), Postives = 407/478 (85.15%), Query Frame = 2 
Query:   53 ADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKTTNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIIIDGGNSEFNDSTRRCRQLAEKNILFXXXXXXXXXXXARYGPSLMPGGNIEAWKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLICEAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEYLLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRMEASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQNKWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREILKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDLFGAHQYQLLDNPSAYHHCNWTGTSGSAAASTY 1486
            AD+GLIGLAVMGQNLVLNM   G+ VCVFNRTL  + KFL+N  K T VIGA SLE+ V KL SPRKI+LLVKAGQ VDDFI  L+PLL+ GDIIIDGGNSE++DSTRRC+ LA K ILFVGSGVSGGEEGAR GPSLMPGGN EAWKHIQ IFQ IAAK  N EPCCDWVG +G+GHFVKMVHNGIEYGDMQLICEAYHLMRD L MGN+EIS  F  WN SELESFLIEIT+ ITKF+  +G YL+  IYDSAGQKGTGKWTAI ALD GVPVTLIAESVFAR LS LK +R+EASKRFPS+    FTGNK EFLN +K ALYASKIISYTQGFMMM++A+ + KW L+LGKIALMWRGGCIIRSRFLQNIKEAY+K++NL +LLFDE+FQ+E+LKCQ SWR+VVS A L G+PTPAFS AL+FYDGLRTE LPANL+QAQRDLFGAHQYQLL++P  Y H +WTG  G+AAASTY
Sbjct:    4 ADIGLIGLAVMGQNLVLNMNEHGYKVCVFNRTLSTVQKFLDNEAKNTKVIGATSLEDLVDKLVSPRKIILLVKAGQPVDDFIQKLVPLLHPGDIIIDGGNSEYHDSTRRCQDLAAKKILFVGSGVSGGEEGARNGPSLMPGGNAEAWKHIQLIFQDIAAKANNGEPCCDWVGSDGAGHFVKMVHNGIEYGDMQLICEAYHLMRDLLDMGNEEISNAFANWNNSELESFLIEITSQITKFKANDGAYLVEDIYDSAGQKGTGKWTAITALDFGVPVTLIAESVFARSLSALKTLRVEASKRFPSDDIQTFTGNKTEFLNQIKYALYASKIISYTQGFMMMRSAAQEFKWDLDLGKIALMWRGGCIIRSRFLQNIKEAYDKNKNLPILLFDEFFQKEVLKCQKSWRQVVSVAALHGIPTPAFSCALSFYDGLRTEKLPANLIQAQRDLFGAHQYQLLEHPGTYEHTDWTGHGGNAAASTY 481
The following BLAST results are available for this feature:
BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PGD0.000e+065.14phosphogluconate dehydrogenase [Source:HGNC Symbol... [more]
PGD1.777e-11967.51phosphogluconate dehydrogenase [Source:HGNC Symbol... [more]
PGD3.549e-9974.15phosphogluconate dehydrogenase [Source:HGNC Symbol... [more]
PGD1.107e-9066.33phosphogluconate dehydrogenase [Source:HGNC Symbol... [more]
PGD1.547e-6973.13phosphogluconate dehydrogenase [Source:HGNC Symbol... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
T25B9.90.000e+060.836-phosphogluconate dehydrogenase, decarboxylating ... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Pgd0.000e+063.05gene:FBgn0004654 transcript:FBtr0070384[more]
Pgd0.000e+063.05gene:FBgn0004654 transcript:FBtr0331410[more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pgd0.000e+065.55phosphogluconate dehydrogenase [Source:ZFIN;Acc:ZD... [more]
pgd0.000e+065.55phosphogluconate dehydrogenase [Source:ZFIN;Acc:ZD... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PGD0.000e+067.02phosphogluconate dehydrogenase [Source:NCBI gene;A... [more]
PGD0.000e+067.02phosphogluconate dehydrogenase [Source:NCBI gene;A... [more]
PGD0.000e+065.76phosphogluconate dehydrogenase [Source:NCBI gene;A... [more]
PGD0.000e+065.48phosphogluconate dehydrogenase [Source:NCBI gene;A... [more]
PGD0.000e+065.45phosphogluconate dehydrogenase [Source:NCBI gene;A... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Pgd0.000e+064.74phosphogluconate dehydrogenase [Source:MGI Symbol;... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P52209|6PGD_HUMAN0.000e+065.146-phosphogluconate dehydrogenase, decarboxylating ... [more]
sp|Q9DCD0|6PGD_MOUSE0.000e+064.746-phosphogluconate dehydrogenase, decarboxylating ... [more]
sp|P85968|6PGD_RAT0.000e+064.966-phosphogluconate dehydrogenase, decarboxylating ... [more]
sp|P00349|6PGD_SHEEP0.000e+064.746-phosphogluconate dehydrogenase, decarboxylating ... [more]
sp|P41572|6PGD_DROME0.000e+063.056-phosphogluconate dehydrogenase, decarboxylating ... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3H7B50.000e+067.576-phosphogluconate dehydrogenase, decarboxylating ... [more]
Q6TNR80.000e+065.976-phosphogluconate dehydrogenase, decarboxylating ... [more]
A0A091R7120.000e+066.536-phosphogluconate dehydrogenase, decarboxylating ... [more]
A0A093QYB30.000e+066.536-phosphogluconate dehydrogenase, decarboxylating ... [more]
A0A553RNG10.000e+066.396-phosphogluconate dehydrogenase, decarboxylating ... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pgd0.000e+065.76phosphogluconate dehydrogenase [Source:NCBI gene;A... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
GND20.000e+058.986-phosphogluconate dehydrogenase (decarboxylating)... [more]
GND10.000e+059.226-phosphogluconate dehydrogenase (decarboxylating)... [more]
YHR182C-A_mRNA9.795e-1126.75Dubious open reading frame; unlikely to encode a f... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO353130.000e+065.146-phosphogluconate dehydrogenase, decarboxylating ... [more]
EDO287806.088e-15666.776-phosphogluconate dehydrogenase, decarboxylating ... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
pgd0.000e+064.44phosphogluconate dehydrogenase [Source:NCBI gene;A... [more]
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BLAST of 6-phosphogluconate dehydrogenase, decarboxylating vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000005726.10.000e+095.61SMESG000005726.1[more]
SMESG000005726.10.000e+095.03SMESG000005726.1[more]
SMESG000005722.10.000e+095.12SMESG000005722.1[more]
SMESG000005724.10.000e+075.10SMESG000005724.1[more]
SMESG000005721.10.000e+076.36SMESG000005721.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021922 ID=SMED30021922|Name=6-phosphogluconate dehydrogenase, decarboxylating|organism=Schmidtea mediterranea sexual|type=transcript|length=1677bp
CTATATAAATCTTATATGATTTTCAAGTGAATTATAGAAAATGATTCTTA
ATGCAGATCTTGGGTTAATTGGACTTGCAGTAATGGGGCAGAATCTTGTG
CTGAATATGGCTGGTCAAGGATTTGGGGTTTGTGTTTTCAATCGAACTCT
GTTGGTGATGGATAAATTTTTAAACAACTTACCAAAAACTACAAATGTAA
TAGGTGCAAGGTCTCTGGAGGAATTCGTCAGTAAATTGAAGTCTCCCAGG
AAAATAATGTTACTTGTAAAGGCGGGCCAAGCAGTTGATGATTTTATTAA
CAATCTGATACCTCTTCTAAATTCTGGTGACATAATAATAGATGGAGGAA
ATTCTGAATTTAATGACTCTACGAGAAGATGTCGACAATTAGCTGAAAAG
AATATTTTATTTGTTGGATCTGGTGTAAGTGGAGGCGAAGAAGGAGCAAG
ATATGGACCGAGTCTCATGCCCGGTGGAAACATCGAAGCTTGGAAGCATA
TTCAACCGATTTTCCAAGCAATTGCTGCTAAAGTAGAGAACAACGAGCCT
TGCTGTGATTGGGTAGGGTTGGAAGGTTCAGGACATTTTGTGAAAATGGT
CCACAATGGAATCGAATATGGAGATATGCAGTTAATTTGTGAAGCGTATC
ATTTGATGAGAGATTTCTTGCATATGGGAAATGACGAGATATCGGAGACA
TTCGACGCCTGGAACAAAAGTGAGCTCGAATCGTTCCTCATTGAGATCAC
AACCATTATAACAAAGTTTCAAAATGAAAATGGAGAATATTTGCTAAATC
AAATTTATGATTCTGCCGGTCAGAAAGGTACCGGGAAATGGACAGCAATC
AACGCGTTAGATTTAGGAGTTCCTGTTACACTTATTGCTGAAAGTGTTTT
TGCACGTTGTTTGTCTGGATTGAAACCGGTCCGCATGGAAGCAAGTAAGA
GATTCCCATCTAATAGCAGTCATAAATTCACGGGAAACAAAGATGAATTC
CTAAATGATCTGAAACTGGCCTTATATGCTAGCAAGATCATTTCATACAC
CCAAGGATTCATGATGATGAAAACGGCATCAGATCAAAACAAATGGAGTT
TGAATTTAGGAAAAATCGCATTGATGTGGAGAGGAGGATGCATTATAAGG
AGCCGATTTCTACAAAACATCAAAGAAGCATATGAAAAAGATGAAAATTT
GTCTGTTCTTCTTTTCGATGAATATTTTCAAAGAGAAATTTTGAAATGTC
AAACAAGTTGGAGAAAAGTCGTGTCCACTGCAGTGCTAGAAGGTTTACCT
ACTCCTGCATTTTCATCAGCTCTTGCGTTTTATGACGGATTACGAACAGA
AAATTTGCCGGCAAATCTACTACAAGCACAACGAGATTTATTTGGTGCTC
ATCAATATCAGTTATTGGATAATCCGAGCGCATATCACCATTGCAATTGG
ACCGGAACGAGTGGATCGGCCGCTGCGTCAACATATACATGTTGACAGTT
TGCGTGAAAATTTTGTTATTAAAATTGAAATTAAAGACCTCAAAGAGCTT
ATTTTGGACACTGATCTTGTTGATGTGCAAAATCGACAGTTTTTTAACCT
CTTAATGCCGTATAGATTCGTCATGGTTTATTGCTTTTTCGTAGCTCTTA
TATCGAATATATTCATATTATGAAACA
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protein sequence of SMED30021922-orf-1

>SMED30021922-orf-1 ID=SMED30021922-orf-1|Name=SMED30021922-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=485bp
MILNADLGLIGLAVMGQNLVLNMAGQGFGVCVFNRTLLVMDKFLNNLPKT
TNVIGARSLEEFVSKLKSPRKIMLLVKAGQAVDDFINNLIPLLNSGDIII
DGGNSEFNDSTRRCRQLAEKNILFVGSGVSGGEEGARYGPSLMPGGNIEA
WKHIQPIFQAIAAKVENNEPCCDWVGLEGSGHFVKMVHNGIEYGDMQLIC
EAYHLMRDFLHMGNDEISETFDAWNKSELESFLIEITTIITKFQNENGEY
LLNQIYDSAGQKGTGKWTAINALDLGVPVTLIAESVFARCLSGLKPVRME
ASKRFPSNSSHKFTGNKDEFLNDLKLALYASKIISYTQGFMMMKTASDQN
KWSLNLGKIALMWRGGCIIRSRFLQNIKEAYEKDENLSVLLFDEYFQREI
LKCQTSWRKVVSTAVLEGLPTPAFSSALAFYDGLRTENLPANLLQAQRDL
FGAHQYQLLDNPSAYHHCNWTGTSGSAAASTYTC*
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protein sequence of SMED30021922-orf-2

>SMED30021922-orf-2 ID=SMED30021922-orf-2|Name=SMED30021922-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=114bp
MTDYEQKICRQIYYKHNEIYLVLINISYWIIRAHITIAIGPERVDRPLRQ
HIHVDSLRENFVIKIEIKDLKELILDTDLVDVQNRQFFNLLMPYRFVMVY
CFFVALISNIFIL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0050661NADP binding
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity
GO:0016491oxidoreductase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000418head
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR036291NAD(P)-bd_dom_sf
IPR006183Pgluconate_DH
IPR0061146PGDH_C
IPR016040NAD(P)-bd_dom
IPR0133286PGD_dom2
IPR0061136PGDH_Gnd/GntZ
IPR0122846PGD_dom_3
IPR0061156PGDH_NADP-bd
IPR0061846PGdom_BS
IPR0089276-PGluconate_DH-like_C_sf
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
GO:0006098pentose-phosphate shunt
GO:0009051pentose-phosphate shunt, oxidative branch
GO:0019322pentose biosynthetic process
GO:0019521D-gluconate metabolic process
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005829cytosol
GO:0070062extracellular exosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR0061836-phosphogluconate dehydrogenasePRINTSPR000766PGDHDRGNASEcoord: 5..28
score: 61.5
coord: 68..97
score: 53.77
coord: 170..198
score: 76.46
coord: 251..278
score: 61.96
coord: 359..381
score: 66.07
coord: 121..146
score: 75.08
IPR0061836-phosphogluconate dehydrogenasePANTHERPTHR118116-PHOSPHOGLUCONATE DEHYDROGENASEcoord: 4..483
IPR0061146-phosphogluconate dehydrogenase, C-terminalSMARTSM013506PGD_2coord: 181..471
e-value: 6.1E-192
score: 653.6
IPR0061146-phosphogluconate dehydrogenase, C-terminalPFAMPF003936PGDcoord: 181..470
e-value: 4.0E-123
score: 410.4
NoneNo IPR availableGENE3DG3DSA:3.40.50.720coord: 3..182
e-value: 1.2E-51
score: 177.3
NoneNo IPR availableGENE3DG3DSA:1.20.5.320coord: 438..484
e-value: 2.8E-19
score: 70.7
NoneNo IPR availablePANTHERPTHR11811:SF506-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATINGcoord: 4..483
IPR0061136-phosphogluconate dehydrogenase, decarboxylatingPIRSFPIRSF0001096PGDcoord: 1..479
e-value: 5.7E-227
score: 751.6
IPR0061136-phosphogluconate dehydrogenase, decarboxylatingTIGRFAMTIGR00873TIGR00873coord: 6..471
e-value: 1.1E-214
score: 711.5
IPR0061156-phosphogluconate dehydrogenase, NADP-bindingPFAMPF03446NAD_binding_2coord: 6..166
e-value: 1.1E-47
score: 162.1
IPR0133286-phosphogluconate dehydrogenase, domain 2GENE3DG3DSA:1.10.1040.10coord: 183..437
e-value: 5.4E-105
score: 352.3
IPR0061846-phosphogluconate-binding sitePROSITEPS004616PGDcoord: 255..267
IPR0089276-phosphogluconate dehydrogenase-like, C-terminal domain superfamilySUPERFAMILYSSF481796-phosphogluconate dehydrogenase C-terminal domain-likecoord: 179..474
IPR036291NAD(P)-binding domain superfamilySUPERFAMILYSSF51735NAD(P)-binding Rossmann-fold domainscoord: 5..175