Dynein light chain

Overview
NameDynein light chain
Smed IDSMED30021918
Length (bp)590
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Dynein light chain (SMED30021918) t-SNE clustered cells

Violin plots show distribution of expression levels for Dynein light chain (SMED30021918) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dynein light chain (SMED30021918) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dynein light chain (SMED30021918) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30021918

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
cephalic gangliaSMED30021918 dd_Smed_v4_13760_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30021918 dd_Smed_v4_13760_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
zeta neoblastSMED30021918 dd_Smed_v4_13760_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DNAL4 (dynein axonemal light chain 4 [Source:HGNC Symbol;Acc:HGNC:2955])

HSP 1 Score: 115.931 bits (289), Expect = 4.270e-33
Identity = 53/90 (58.89%), Postives = 67/90 (74.44%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++ T PLV  + M EEM  E  ELCVTACEKF  NN SAA MIKE MDK+FG SW VV+GE F  ++T+ VKNLLYL++GG +A+ +WK
Sbjct:   14 KRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWK 103
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 62.003 bits (149), Expect = 1.625e-12
Identity = 38/93 (40.86%), Postives = 54/93 (58.06%), Query Frame = 3 
Query:  231 CLRKVNTIPLVIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            C RK      VIKN  M+EEM  ++ E    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    2 CDRKA-----VIKNADMSEEMQQDSVECATQALEKYNIEKDIAA-HIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 62.003 bits (149), Expect = 1.625e-12
Identity = 38/93 (40.86%), Postives = 54/93 (58.06%), Query Frame = 3 
Query:  231 CLRKVNTIPLVIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            C RK      VIKN  M+EEM  ++ E    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    2 CDRKA-----VIKNADMSEEMQQDSVECATQALEKYNIEKDIAA-HIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 62.003 bits (149), Expect = 1.625e-12
Identity = 38/93 (40.86%), Postives = 54/93 (58.06%), Query Frame = 3 
Query:  231 CLRKVNTIPLVIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            C RK      VIKN  M+EEM  ++ E    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    2 CDRKA-----VIKNADMSEEMQQDSVECATQALEKYNIEKDIAA-HIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 62.003 bits (149), Expect = 1.625e-12
Identity = 38/93 (40.86%), Postives = 54/93 (58.06%), Query Frame = 3 
Query:  231 CLRKVNTIPLVIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            C RK      VIKN  M+EEM  ++ E    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    2 CDRKA-----VIKNADMSEEMQQDSVECATQALEKYNIEKDIAA-HIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 59.6918 bits (143), Expect = 4.657e-12
Identity = 33/83 (39.76%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+++M  +A +    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSDDMQQDAIDCATQALEKYNIEKDIAAY-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 59.6918 bits (143), Expect = 4.657e-12
Identity = 33/83 (39.76%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+++M  +A +    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSDDMQQDAIDCATQALEKYNIEKDIAAY-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 59.6918 bits (143), Expect = 4.657e-12
Identity = 33/83 (39.76%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+++M  +A +    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSDDMQQDAIDCATQALEKYNIEKDIAAY-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: CG8407 (gene:FBgn0033687 transcript:FBtr0087985)

HSP 1 Score: 105.531 bits (262), Expect = 1.866e-29
Identity = 50/88 (56.82%), Postives = 62/88 (70.45%), Query Frame = 3 
Query:  243 VNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            V+  PLV    MNEEM  EA EL +TACEK+  N   AA +IKE MDK+FG  W VVVGE F  +V+Y  +N+LYLF+ GN+AI+LWK
Sbjct:   15 VHVYPLVKHTDMNEEMRIEAIELSITACEKYSSNYEHAAKIIKENMDKKFGIYWHVVVGEGFGFEVSYETENILYLFFAGNLAIVLWK 102
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: CG8407 (gene:FBgn0033687 transcript:FBtr0301127)

HSP 1 Score: 105.531 bits (262), Expect = 1.866e-29
Identity = 50/88 (56.82%), Postives = 62/88 (70.45%), Query Frame = 3 
Query:  243 VNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            V+  PLV    MNEEM  EA EL +TACEK+  N   AA +IKE MDK+FG  W VVVGE F  +V+Y  +N+LYLF+ GN+AI+LWK
Sbjct:   15 VHVYPLVKHTDMNEEMRIEAIELSITACEKYSSNYEHAAKIIKENMDKKFGIYWHVVVGEGFGFEVSYETENILYLFFAGNLAIVLWK 102
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: Cdlc2 (gene:FBgn0026141 transcript:FBtr0077924)

HSP 1 Score: 62.003 bits (149), Expect = 8.467e-13
Identity = 34/83 (40.96%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+EEM  +A +    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  ++ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAF-IKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: Cdlc2 (gene:FBgn0026141 transcript:FBtr0305553)

HSP 1 Score: 62.003 bits (149), Expect = 8.467e-13
Identity = 34/83 (40.96%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+EEM  +A +    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  ++ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAF-IKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: Cdlc2 (gene:FBgn0026141 transcript:FBtr0077925)

HSP 1 Score: 62.003 bits (149), Expect = 8.467e-13
Identity = 34/83 (40.96%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+EEM  +A +    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  ++ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSEEMQQDAVDCATQALEKYNIEKDIAAF-IKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dnal4a (dynein, axonemal, light chain 4a [Source:ZFIN;Acc:ZDB-GENE-040801-122])

HSP 1 Score: 115.546 bits (288), Expect = 3.118e-33
Identity = 51/90 (56.67%), Postives = 68/90 (75.56%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++ + PL+    M EEM  E  ELCVTACEKF  NN SAA MIKE+MDK+FG SW VV+GE F  +VT+ V+NLLY+F+GG++A+ +WK
Sbjct:   15 KRLQSFPLIRHTDMPEEMRVETMELCVTACEKFASNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEVTHEVRNLLYMFFGGSLAVCVWK 104
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dnal4a (dynein, axonemal, light chain 4a [Source:ZFIN;Acc:ZDB-GENE-040801-122])

HSP 1 Score: 115.546 bits (288), Expect = 3.118e-33
Identity = 51/90 (56.67%), Postives = 68/90 (75.56%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++ + PL+    M EEM  E  ELCVTACEKF  NN SAA MIKE+MDK+FG SW VV+GE F  +VT+ V+NLLY+F+GG++A+ +WK
Sbjct:   15 KRLQSFPLIRHTDMPEEMRVETMELCVTACEKFASNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEVTHEVRNLLYMFFGGSLAVCVWK 104
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dnal4b (dynein, axonemal, light chain 4b [Source:ZFIN;Acc:ZDB-GENE-050208-510])

HSP 1 Score: 115.546 bits (288), Expect = 3.152e-33
Identity = 51/90 (56.67%), Postives = 68/90 (75.56%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            ++++  PL+    M EEM  E  ELCVTACEKF  NN SAA MIKE+MDK+FG SW VV+GE F  ++T+ VKNLLY+F+GG++A+ +WK
Sbjct:   15 KRLHNFPLIRHTDMPEEMRVETMELCVTACEKFATNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEITHEVKNLLYMFFGGSLAVCVWK 104
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dnal4b (dynein, axonemal, light chain 4b [Source:ZFIN;Acc:ZDB-GENE-050208-510])

HSP 1 Score: 115.546 bits (288), Expect = 3.152e-33
Identity = 51/90 (56.67%), Postives = 68/90 (75.56%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            ++++  PL+    M EEM  E  ELCVTACEKF  NN SAA MIKE+MDK+FG SW VV+GE F  ++T+ VKNLLY+F+GG++A+ +WK
Sbjct:   15 KRLHNFPLIRHTDMPEEMRVETMELCVTACEKFATNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEITHEVKNLLYMFFGGSLAVCVWK 104
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dnal4b (dynein, axonemal, light chain 4b [Source:ZFIN;Acc:ZDB-GENE-050208-510])

HSP 1 Score: 115.546 bits (288), Expect = 3.152e-33
Identity = 51/90 (56.67%), Postives = 68/90 (75.56%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            ++++  PL+    M EEM  E  ELCVTACEKF  NN SAA MIKE+MDK+FG SW VV+GE F  ++T+ VKNLLY+F+GG++A+ +WK
Sbjct:   15 KRLHNFPLIRHTDMPEEMRVETMELCVTACEKFATNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEITHEVKNLLYMFFGGSLAVCVWK 104
[Close]
BLAST of Dynein light chain vs. Ensembl Xenopus
Match: rnf181 (ring finger protein 181 [Source:Xenbase;Acc:XB-GENE-964051])

HSP 1 Score: 116.316 bits (290), Expect = 2.554e-33
Identity = 52/90 (57.78%), Postives = 68/90 (75.56%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++++ PL+    M EEM  E  ELCVTACEKF  NN SAA MIKE MDK+FG SW VV+GE F  ++T+ VKNLLY+F+GG++AI +WK
Sbjct:   15 KRMHSFPLIRHTDMPEEMRVETMELCVTACEKFASNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYMFFGGSLAICVWK 104
[Close]
BLAST of Dynein light chain vs. Ensembl Xenopus
Match: dynll1 (dynein light chain LC8-type 1 [Source:NCBI gene;Acc:448652])

HSP 1 Score: 64.3142 bits (155), Expect = 2.354e-13
Identity = 36/83 (43.37%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+EEM  +A +    A EKF +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSEEMQQDAVDCATQALEKFNIEKDIAAF-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Xenopus
Match: dynll2 (dynein light chain LC8-type 2 [Source:NCBI gene;Acc:100038056])

HSP 1 Score: 60.8474 bits (146), Expect = 4.535e-12
Identity = 34/83 (40.96%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+E+M  +A +    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAY-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dnal4 (dynein, axonemal, light chain 4 [Source:MGI Symbol;Acc:MGI:1859217])

HSP 1 Score: 115.931 bits (289), Expect = 2.900e-33
Identity = 53/90 (58.89%), Postives = 67/90 (74.44%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++ T PLV  + M EEM  E  ELCVTACEKF  NN SAA MIKE MDK+FG SW VV+GE F  ++T+ VKNLLYL++GG +A+ +WK
Sbjct:   14 KRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWK 103
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dnal4 (dynein, axonemal, light chain 4 [Source:MGI Symbol;Acc:MGI:1859217])

HSP 1 Score: 115.931 bits (289), Expect = 2.900e-33
Identity = 53/90 (58.89%), Postives = 67/90 (74.44%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++ T PLV  + M EEM  E  ELCVTACEKF  NN SAA MIKE MDK+FG SW VV+GE F  ++T+ VKNLLYL++GG +A+ +WK
Sbjct:   14 KRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWK 103
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dnal4 (dynein, axonemal, light chain 4 [Source:MGI Symbol;Acc:MGI:1859217])

HSP 1 Score: 88.9669 bits (219), Expect = 2.336e-22
Identity = 41/70 (58.57%), Postives = 50/70 (71.43%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTY 446
            +++ T PLV  + M EEM  E  ELCVTACEKF  NN SAA MIKE MDK+FG SW VV+GE F  ++T+
Sbjct:   14 KRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITH 83
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dnal4 (dynein, axonemal, light chain 4 [Source:MGI Symbol;Acc:MGI:1859217])

HSP 1 Score: 77.411 bits (189), Expect = 1.318e-18
Identity = 32/52 (61.54%), Postives = 42/52 (80.77%), Query Frame = 3 
Query:  351 SAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            SAA MIKE MDK+FG SW VV+GE F  ++T+ VKNLLYL++GG +A+ +WK
Sbjct:   24 SAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWK 75
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll1 (dynein light chain LC8-type 1 [Source:MGI Symbol;Acc:MGI:1861457])

HSP 1 Score: 62.003 bits (149), Expect = 1.115e-12
Identity = 38/93 (40.86%), Postives = 54/93 (58.06%), Query Frame = 3 
Query:  231 CLRKVNTIPLVIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            C RK      VIKN  M+EEM  ++ E    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    2 CDRKA-----VIKNADMSEEMQQDSVECATQALEKYNIEKDIAA-HIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q9DCM4|DNAL4_MOUSE (Dynein light chain 4, axonemal OS=Mus musculus OX=10090 GN=Dnal4 PE=3 SV=2)

HSP 1 Score: 115.931 bits (289), Expect = 2.028e-32
Identity = 53/90 (58.89%), Postives = 67/90 (74.44%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++ T PLV  + M EEM  E  ELCVTACEKF  NN SAA MIKE MDK+FG SW VV+GE F  ++T+ VKNLLYL++GG +A+ +WK
Sbjct:   14 KRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWK 103
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|A4F4L4|DNAL4_PIG (Dynein light chain 4, axonemal OS=Sus scrofa OX=9823 GN=DNAL4 PE=3 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 2.050e-32
Identity = 53/90 (58.89%), Postives = 67/90 (74.44%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++ T PLV  + M EEM  E  ELCVTACEKF  NN SAA MIKE MDK+FG SW VV+GE F  ++T+ VKNLLYL++GG +A+ +WK
Sbjct:   14 KRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWK 103
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|O96015|DNAL4_HUMAN (Dynein light chain 4, axonemal OS=Homo sapiens OX=9606 GN=DNAL4 PE=1 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 2.050e-32
Identity = 53/90 (58.89%), Postives = 67/90 (74.44%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++ T PLV  + M EEM  E  ELCVTACEKF  NN SAA MIKE MDK+FG SW VV+GE F  ++T+ VKNLLYL++GG +A+ +WK
Sbjct:   14 KRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWK 103
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q32KN5|DNAL4_BOVIN (Dynein light chain 4, axonemal OS=Bos taurus OX=9913 GN=DNAL4 PE=3 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 2.050e-32
Identity = 53/90 (58.89%), Postives = 67/90 (74.44%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++ T PLV  + M EEM  E  ELCVTACEKF  NN SAA MIKE MDK+FG SW VV+GE F  ++T+ VKNLLYL++GG +A+ +WK
Sbjct:   14 KRLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWK 103
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q9UR05|DYL1_SCHPO (Dynein light chain 1, cytoplasmic OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=dlc2 PE=3 SV=1)

HSP 1 Score: 62.003 bits (149), Expect = 7.289e-12
Identity = 32/77 (41.56%), Postives = 45/77 (58.44%), Query Frame = 3 
Query:  276 MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            M+E+M  EA    V A EKF +    AA  IK   DK+F P+W  +VG +F   VT+  ++ +Y FY G +A LL+K
Sbjct:    9 MSEKMQQEAIHAAVQAMEKFTIEKDIAAF-IKREFDKKFSPTWHCIVGRNFGSFVTHESRHFIY-FYLGTVAFLLFK 83
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A267F3Z6 (Dynein light chain OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002549g1 PE=3 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 4.927e-35
Identity = 57/90 (63.33%), Postives = 74/90 (82.22%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            R+V+T PLV  + MNEEM +EA ELCVTACEKF  NN SAA MIK++MDK+FGP+W  VVGE +  ++T+ +KNL+Y+F+GGNMAI+LWK
Sbjct:   13 RRVHTYPLVRYSDMNEEMRTEAMELCVTACEKFASNNESAARMIKDSMDKKFGPAWHAVVGEGYGFEITHELKNLMYMFFGGNMAIILWK 102
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A3M7S817 (Dynein light chain OS=Brachionus plicatilis OX=10195 GN=BpHYR1_049173 PE=3 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 4.607e-34
Identity = 57/94 (60.64%), Postives = 72/94 (76.60%), Query Frame = 3 
Query:  225 EECLRKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +E   K +T PL+  + M+EEM +EA ELCVTACEKF  NN  AA MIKE +DK+FGP+W VVVGE F  ++T+ VKN+LY+F+GGN AILLWK
Sbjct:   11 KEDTSKRHTYPLIRNSDMHEEMRTEAMELCVTACEKFSSNNEGAARMIKETLDKKFGPAWHVVVGEGFGFEITHEVKNILYMFFGGNQAILLWK 104
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A433TQB4 (Dynein light chain OS=Elysia chlorotica OX=188477 GN=EGW08_008548 PE=3 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 8.021e-34
Identity = 55/90 (61.11%), Postives = 72/90 (80.00%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            ++V+T PL+  + MN+EM +EA ELCVTACEKF  NN +AA MIK+ MDK+FG SW  VVGE +  ++T+ VKNLLY+F+GGNMAI+LWK
Sbjct:   15 KRVHTYPLIRHSDMNDEMKTEAMELCVTACEKFSSNNETAAKMIKDTMDKKFGASWHAVVGEGYGFEITHEVKNLLYMFFGGNMAIILWK 104
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: V3YVH6 (Dynein light chain OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_204935 PE=3 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 9.623e-34
Identity = 55/90 (61.11%), Postives = 72/90 (80.00%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            ++V+T PL+  + MN+EM +EA ELCVTACEKF  NN +AA MIKE MDK+FG SW  VVGE +  ++T+ VKNLLY+F+GGNMAI++WK
Sbjct:   16 KRVHTYPLIRHSDMNDEMKTEAMELCVTACEKFSANNENAAKMIKETMDKKFGASWHAVVGEGYGFEITHEVKNLLYMFFGGNMAIMIWK 105
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A0B7BXJ1 (Dynein light chain (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF214611 PE=3 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 1.035e-33
Identity = 56/90 (62.22%), Postives = 73/90 (81.11%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            ++++T PL+  + M EEM +EA ELCVTACEKF  NN +AA +IK+ MDK+FG SW VVVGESF  +VT+ VKNLLY+F+GGN+AI+LWK
Sbjct:   25 KRIHTYPLIRHSDMTEEMKNEAMELCVTACEKFVSNNENAAKLIKDTMDKKFGSSWHVVVGESFGFEVTHEVKNLLYMFFGGNIAIILWK 114
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dnal4b (dynein axonemal light chain 4 [Source:NCBI gene;Acc:103029781])

HSP 1 Score: 117.087 bits (292), Expect = 7.106e-34
Identity = 52/90 (57.78%), Postives = 69/90 (76.67%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++++ PL+    M EEM  E  ELCVTACEKF  NN SAA MIKE+MDK+FG SW VV+GE F  +VT+ VKNLLY+F+GG++A+ +WK
Sbjct:   15 KRLHSFPLIRHTDMPEEMRVETMELCVTACEKFATNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEVTHEVKNLLYMFFGGSLAVCVWK 104
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: ENSAMXT00000047143.1 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:103041528])

HSP 1 Score: 60.8474 bits (146), Expect = 2.480e-12
Identity = 34/83 (40.96%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+E+M  +A +    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAY-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dynll2b (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:103041528])

HSP 1 Score: 60.8474 bits (146), Expect = 2.480e-12
Identity = 34/83 (40.96%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+E+M  +A +    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAY-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dynll1 (dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1961])

HSP 1 Score: 57.3806 bits (137), Expect = 9.895e-11
Identity = 30/82 (36.59%), Postives = 45/82 (54.88%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLW 503
            VIKN  M+EEM  +A E    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y + G      +W
Sbjct:    7 VIKNADMSEEMQQDAVECATQALEKYNIEKDIAAY-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQRNGWAVW 87
[Close]
BLAST of Dynein light chain vs. Ensembl Yeast
Match: DYN2 (Cytoplasmic light chain dynein, microtubule motor protein; required for intracellular transport and cell division; involved in mitotic spindle positioning; forms complex with dynein intermediate chain Pac11p that promotes Dyn1p homodimerization, potentiates motor processivity; Dyn2p-Pac11p complex important for interaction of dynein motor complex with dynactin complex; acts as molecular glue to dimerize, stabilize Nup82-Nsp1-Nup159 complex module of cytoplasmic pore filaments [Source:SGD;Acc:S000002832])

HSP 1 Score: 46.2098 bits (108), Expect = 1.189e-7
Identity = 22/86 (25.58%), Postives = 49/86 (56.98%), Query Frame = 3 
Query:  249 TIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            + P+V  + + +++  +   +   A +K+ +    A   +K+ +D ++G +W V+VG++F   VT+   + +Y FY G +A L++K
Sbjct:    7 STPIVKASDITDKLKEDILTISKDALDKYQLERDIAG-TVKKQLDVKYGNTWHVIVGKNFGSYVTHEKGHFVY-FYIGPLAFLVFK 90
[Close]
BLAST of Dynein light chain vs. Ensembl Nematostella
Match: EDO38557 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCP2])

HSP 1 Score: 116.316 bits (290), Expect = 5.782e-34
Identity = 51/90 (56.67%), Postives = 70/90 (77.78%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +++++ PL+  + MN+EM +EA ELCVTACEKF  NN +AA MIKE+MDK+FG SW  VVGE F  ++T+ V+NLLY+F+GG  AI +WK
Sbjct:   19 KRLHSFPLIRYSDMNDEMRTEAMELCVTACEKFSNNNETAAKMIKESMDKKFGASWHAVVGEGFGFEITHEVRNLLYMFFGGTTAICIWK 108
[Close]
BLAST of Dynein light chain vs. Ensembl Nematostella
Match: EDO44582 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVI5])

HSP 1 Score: 63.5438 bits (153), Expect = 1.047e-13
Identity = 36/83 (43.37%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M E+M ++A E    A EKF +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMAEDMQTDAIECATQALEKFNIEKDIAAF-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: dnal4b (dynein axonemal light chain 4 [Source:NCBI gene;Acc:101161374])

HSP 1 Score: 110.538 bits (275), Expect = 2.265e-31
Identity = 49/90 (54.44%), Postives = 67/90 (74.44%), Query Frame = 3 
Query:  237 RKVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            ++++  PL+    M +EM  E  ELCV+ACE F  NN SAA MIKE MDK+FG SW VV+GESF  +VT+ +KNLLY+F+GG++A+ +WK
Sbjct:   15 KRLHNFPLIRHTDMPDEMRIETMELCVSACETFATNNESAAKMIKEHMDKKFGSSWHVVIGESFGFEVTHELKNLLYMFFGGSLAVCVWK 104
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: dynll1 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101171417])

HSP 1 Score: 62.003 bits (149), Expect = 8.259e-13
Identity = 35/83 (42.17%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+E+M  +A E    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSEDMQQDAVECATQALEKYNIEKDIAAY-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: ENSORLT00000005747.2 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101162462])

HSP 1 Score: 62.003 bits (149), Expect = 8.984e-13
Identity = 35/83 (42.17%), Postives = 51/83 (61.45%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+EEM  +A +    A EK+ +    AA  IK+  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSEEMQQDAVDCATQAMEKYNIEKDIAAY-IKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: DYNLL2 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101174042])

HSP 1 Score: 60.4622 bits (145), Expect = 3.953e-12
Identity = 34/83 (40.96%), Postives = 52/83 (62.65%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M++EM  +A +  + A EK+ +    AA + KE  DK++ P+W  +VG +F   VT+  K+ +Y FY G +AILL+K
Sbjct:    7 VIKNADMSDEMQQDAVDCAMQAMEKYNIEKDIAAYVKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIY-FYLGQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000027765.1 (SMESG000027765.1)

HSP 1 Score: 113.62 bits (283), Expect = 1.276e-32
Identity = 49/89 (55.06%), Postives = 70/89 (78.65%), Query Frame = 3 
Query:  240 KVNTIPLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +V+T PLV  + M+EE+ +EA EL VTACEKF  +N +AA M+KE MDK+FG +W V++GE +  ++T+  KNLLY+++GGNMAI+LWK
Sbjct:   14 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 102
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000018122.1 (SMESG000018122.1)

HSP 1 Score: 82.4185 bits (202), Expect = 1.653e-20
Identity = 42/84 (50.00%), Postives = 58/84 (69.05%), Query Frame = 3 
Query:  255 PLVIKNTMNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            PL+    M+EE+  E  E C TACEK Y +N  AA M+KE +D++ G  WQVV+GE +  +VTY  K L+Y+++GGN AIL+WK
Sbjct:   22 PLIRFCDMSEEVRMECAETCQTACEK-YNDNEIAAKMVKETLDQKCGNGWQVVIGEGYGFEVTYDKKCLMYMYFGGNSAILVWK 104
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000052937.1 (SMESG000052937.1)

HSP 1 Score: 77.0258 bits (188), Expect = 1.053e-18
Identity = 29/52 (55.77%), Postives = 43/52 (82.69%), Query Frame = 3 
Query:  351 SAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            +AA M+KE MDK+FG +W V++GE +  ++T+  KNLLY+++GGNMAI+LWK
Sbjct:   23 AAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 74
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000067731.1 (SMESG000067731.1)

HSP 1 Score: 68.1662 bits (165), Expect = 3.236e-15
Identity = 35/83 (42.17%), Postives = 52/83 (62.65%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            ++KN  MNEEM  +A  +   A EKF +    AA  IK+A DK++ P+W V+VG  F   VT+ +K+ +Y FY G  A+L++K
Sbjct:    7 IVKNADMNEEMQRDAINIANEAMEKFKVEKDVAAY-IKKAFDKKYNPNWHVIVGRKFGSYVTHEIKHFIY-FYLGQAAVLIFK 87
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000055712.1 (SMESG000055712.1)

HSP 1 Score: 67.3958 bits (163), Expect = 5.556e-15
Identity = 36/83 (43.37%), Postives = 52/83 (62.65%), Query Frame = 3 
Query:  261 VIKNT-MNEEMCSEATELCVTACEKFYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGGNMAILLWK 506
            VIKN  M+EEM  +A EL   A EK+ +    AA + KE  D+++ PSW  +VG +F   VT+  K+ +Y FY G +A+LL+K
Sbjct:    7 VIKNADMSEEMQQDAIELAALAMEKYNVEKDIAAYLKKE-FDRKYNPSWHAIVGRNFGSYVTHETKHFIY-FYLGQVAVLLFK 87
The following BLAST results are available for this feature:
BLAST of Dynein light chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DNAL44.270e-3358.89dynein axonemal light chain 4 [Source:HGNC Symbol;... [more]
DYNLL11.625e-1240.86dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL11.625e-1240.86dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL11.625e-1240.86dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL11.625e-1240.86dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
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BLAST of Dynein light chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
dlc-14.657e-1239.76Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-14.657e-1239.76Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-14.657e-1239.76Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
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BLAST of Dynein light chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG84071.866e-2956.82gene:FBgn0033687 transcript:FBtr0087985[more]
CG84071.866e-2956.82gene:FBgn0033687 transcript:FBtr0301127[more]
Cdlc28.467e-1340.96gene:FBgn0026141 transcript:FBtr0077924[more]
Cdlc28.467e-1340.96gene:FBgn0026141 transcript:FBtr0305553[more]
Cdlc28.467e-1340.96gene:FBgn0026141 transcript:FBtr0077925[more]
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BLAST of Dynein light chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnal4a3.118e-3356.67dynein, axonemal, light chain 4a [Source:ZFIN;Acc:... [more]
dnal4a3.118e-3356.67dynein, axonemal, light chain 4a [Source:ZFIN;Acc:... [more]
dnal4b3.152e-3356.67dynein, axonemal, light chain 4b [Source:ZFIN;Acc:... [more]
dnal4b3.152e-3356.67dynein, axonemal, light chain 4b [Source:ZFIN;Acc:... [more]
dnal4b3.152e-3356.67dynein, axonemal, light chain 4b [Source:ZFIN;Acc:... [more]
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BLAST of Dynein light chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
rnf1812.554e-3357.78ring finger protein 181 [Source:Xenbase;Acc:XB-GEN... [more]
dynll12.354e-1343.37dynein light chain LC8-type 1 [Source:NCBI gene;Ac... [more]
dynll24.535e-1240.96dynein light chain LC8-type 2 [Source:NCBI gene;Ac... [more]
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BLAST of Dynein light chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dnal42.900e-3358.89dynein, axonemal, light chain 4 [Source:MGI Symbol... [more]
Dnal42.900e-3358.89dynein, axonemal, light chain 4 [Source:MGI Symbol... [more]
Dnal42.336e-2258.57dynein, axonemal, light chain 4 [Source:MGI Symbol... [more]
Dnal41.318e-1861.54dynein, axonemal, light chain 4 [Source:MGI Symbol... [more]
Dynll11.115e-1240.86dynein light chain LC8-type 1 [Source:MGI Symbol;A... [more]
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BLAST of Dynein light chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9DCM4|DNAL4_MOUSE2.028e-3258.89Dynein light chain 4, axonemal OS=Mus musculus OX=... [more]
sp|A4F4L4|DNAL4_PIG2.050e-3258.89Dynein light chain 4, axonemal OS=Sus scrofa OX=98... [more]
sp|O96015|DNAL4_HUMAN2.050e-3258.89Dynein light chain 4, axonemal OS=Homo sapiens OX=... [more]
sp|Q32KN5|DNAL4_BOVIN2.050e-3258.89Dynein light chain 4, axonemal OS=Bos taurus OX=99... [more]
sp|Q9UR05|DYL1_SCHPO7.289e-1241.56Dynein light chain 1, cytoplasmic OS=Schizosacchar... [more]
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BLAST of Dynein light chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267F3Z64.927e-3563.33Dynein light chain OS=Macrostomum lignano OX=28230... [more]
A0A3M7S8174.607e-3460.64Dynein light chain OS=Brachionus plicatilis OX=101... [more]
A0A433TQB48.021e-3461.11Dynein light chain OS=Elysia chlorotica OX=188477 ... [more]
V3YVH69.623e-3461.11Dynein light chain OS=Lottia gigantea OX=225164 GN... [more]
A0A0B7BXJ11.035e-3362.22Dynein light chain (Fragment) OS=Arion vulgaris OX... [more]
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BLAST of Dynein light chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
dnal4b7.106e-3457.78dynein axonemal light chain 4 [Source:NCBI gene;Ac... [more]
ENSAMXT00000047143.12.480e-1240.96dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
dynll2b2.480e-1240.96dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
dynll19.895e-1136.59dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:Z... [more]
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BLAST of Dynein light chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
DYN21.189e-725.58Cytoplasmic light chain dynein, microtubule motor ... [more]
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BLAST of Dynein light chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO385575.782e-3456.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO445821.047e-1343.37Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Dynein light chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
dnal4b2.265e-3154.44dynein axonemal light chain 4 [Source:NCBI gene;Ac... [more]
dynll18.259e-1342.17dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
ENSORLT00000005747.28.984e-1342.17dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
DYNLL23.953e-1240.96dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
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BLAST of Dynein light chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000027765.11.276e-3255.06SMESG000027765.1[more]
SMESG000018122.11.653e-2050.00SMESG000018122.1[more]
SMESG000052937.11.053e-1855.77SMESG000052937.1[more]
SMESG000067731.13.236e-1542.17SMESG000067731.1[more]
SMESG000055712.15.556e-1543.37SMESG000055712.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021918 ID=SMED30021918|Name=Dynein light chain|organism=Schmidtea mediterranea sexual|type=transcript|length=590bp
GTTTAAATATTGTTGATTTTAATATGAAATTTAAGTTATGAAATAAAATA
TTTGTATCAATTTTCAATTTAATTGAAACATACATTTTTAATATTTTTAT
TGTTTTAGTACATCAGCTTTGTAAATAGAAATTAATTATTACTTTCTAAT
TGTGGATAATTGCTGCCATTTTACAAAAGCTAATGAATAGATTTGGATTT
AAGTTATTAAATAATGATATTTTAGAAGAATGCTTAAGGAAAGTCAACAC
CATTCCACTAGTTATAAAAAATACAATGAACGAAGAAATGTGTTCCGAAG
CTACTGAATTATGCGTAACTGCATGCGAAAAGTTTTATATGAATAATTGT
TCAGCGGCTTTGATGATTAAAGAAGCAATGGACAAGAGATTTGGACCATC
CTGGCAAGTTGTTGTCGGAGAGAGTTTTTCCTGTGATGTAACATATGCCG
TTAAGAATCTTCTTTATTTATTCTATGGTGGAAATATGGCTATATTGCTA
TGGAAATATAAATGACAAATTAATTTAATCAAATGATTTATTTGAAATTT
AATTTAGTATAAATGTTATTAAACAATTTAATTTATGTAA
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protein sequence of SMED30021918-orf-1

>SMED30021918-orf-1 ID=SMED30021918-orf-1|Name=SMED30021918-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=111bp
MNRFGFKLLNNDILEECLRKVNTIPLVIKNTMNEEMCSEATELCVTACEK
FYMNNCSAALMIKEAMDKRFGPSWQVVVGESFSCDVTYAVKNLLYLFYGG
NMAILLWKYK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003774motor activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005856cytoskeleton
GO:0005874microtubule
GO:0030286dynein complex
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000101muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR037177DLC_sf
IPR001372Dynein_light_chain_typ-1/2
Vocabulary: biological process
TermDefinition
GO:0007017microtubule-based process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001372Dynein light chain, type 1/2SMARTSM01375Dynein_light_2coord: 20..109
e-value: 2.0E-30
score: 117.1
IPR001372Dynein light chain, type 1/2PFAMPF01221Dynein_lightcoord: 26..108
e-value: 9.6E-24
score: 83.5
IPR001372Dynein light chain, type 1/2PANTHERPTHR11886DYNEIN LIGHT CHAINcoord: 18..109
IPR037177Dynein light chain superfamilyGENE3DG3DSA:3.30.740.10coord: 14..109
e-value: 1.9E-23
score: 84.2
IPR037177Dynein light chain superfamilySUPERFAMILYSSF54648DLCcoord: 23..109
NoneNo IPR availablePANTHERPTHR11886:SF2DYNEIN LIGHT CHAINcoord: 18..109