Mediator of RNA polymerase II transcription subunit 12-like protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021839 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Human
Match: MED12L (mediator complex subunit 12L [Source:HGNC Symbol;Acc:HGNC:16050]) HSP 1 Score: 504.212 bits (1297), Expect = 9.223e-146 Identity = 487/1780 (27.36%), Postives = 830/1780 (46.63%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIR--IKLMRNTIDH------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC-SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHG--------LCNSVNLLLTNNKH----PDRS----------------ITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLN---RDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVV---------SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARG-LFESVANLPLPPIGGFLSVAHNXXXXXHRKSPELDRMSTGDNPDSVRSE--------CSGLNQILPSIPIVDYRNFN--RHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKL-ENVFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTII---VETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQ----NSTANSVSAFKKE-DVNLLSSSLQKVTTELLVDLLKMLAVHSD------------------KGRLQDQDYFDL--TENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLI-DKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDT--MNRTFTNLNIWSLHFDQMKIQLLLTQIPEE-------ERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTE----SIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIH-TLFSIPNHGI---------KFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P +EH SA++I + P + + + +++ + N QDT K+K V KD + +S+ I+ W L+ P + ++ K++P KKEDV + KY VP+ RA W IK++ + + +E+ KK R D +W R L E+L I + +T D E E + ++EY +L M+ E +L+ E L W++ E+ D+ ++K LP +L + D F +S L+R+L + L +S NLL ++ H P+ S + ++++ SC+ H +++ LS ++ +++L CP A+V+N + N L + PG N R I ++EQ I QR AVE +W SF+ E TA I V E+LDR+ ++ S+ E L + + N ++ LLCEW+VS R+G HR VA++++ I + +S QN L+ FLDT++P + D + F NLV LF E I ++FS + YM +I+RG L + + P P+G A S H E+ G++ ++ + C L + ++ N++ RHLQY HFPIP+++ HE N R+ LY + RD + L+++ KDI K+ K+ + E +K+R++ +E + E++ ++ + L+Y+D V SQ + + S ++ LP I + +L+E + N + LI + ++ L+ + + + L+ + SL SY + +CI+ L ++ S L+ D ++F G+ + ++ V S RC A + + SC+ LRS F K+ + ++ N+ P D +D++E+ +M+ L N R+S V N L++V C RIN I E + ++LS+EW+ + +L N V FN +L + +DL F+++++T IA ++ARQCF D + V +L + P R+ +L LF Q +T + D +LL+++ + + +LK + + D +G D + D+ N S G +SI E + + + VLR IC WV +E P RL D LI D +SN QA+ LL +IC+P CT D + + R NL W+L +++QL++ Q ++ E ++++N++K I +F+ A+ N +N + + S RQ + S E +L+ LI +LP + + +++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL +Q+ + N +E E+ DD++ + ++H +++ RL LVG +FD +Q S + DW LLL ++I G V+MH+++ ELF TVLDM+ LI+ TL S ++ + ++KKL+KE+ DK + E ++ ++ LLP K T DVI P+ ++ ++ + KQG V K++++PW++ EG KN LS WF V D V+ EE +L++ H HP + +P +YY
Sbjct: 19 LGPPDVYPQDPKQKEDELTAVNVKQGFN-NQPAFTGDEHGSARNI----VINP--SKIGAYFSSILAEKLKLNTFQDTGKKKPQVNA--KDNYWL-VTARSQSAIHSWFSDLAGNKPLS-ILAKKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKK-RQAPDPNLEWTQISTRYLREQLAKISDFYHMASSTGDGPVPVPPEVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIRPMDDDLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSPNLLAAHSPHMMIGPNNSSIGAPSPGPPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKSANPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRW---SFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSSSLAGSSLPVFQNVLLRFLDTQAPSLSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTRPRSPVG---ENADEHYSKDHDVKMEIFSPMPGESCENANTSLGRRMSVNCEKLVKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTETGVGDEG--QKARKNKQETFPTL----ETVFTKLQLLSYFDQHQVTSQISNNVLEQI-------TSFASGTSYHLPLAHHIQLIFDLMEPALNINGLI----DFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLG-----KILSDNAANRYSFVCNTLMNV--CMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-------HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADA----EPGARMTCRLLLHLFRAPQACFLPQATGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNSVSSLKNDDFTMRGLRCDGNADDIWTASQNPKSCG----KSISIETANLR----EYARYVLRTICQQEWVGEHCLKE-PERLCTDKELILDPVLSNMQAQKLLQLICYPHGI---KECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSADLN-NSSNSGMSLFNPNSIGSADTSSTRQNGIKTFLSSSERRGVWLVAPLIARLP-TSVQGRVLKAAGEELEKGQHLGS-SSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWRE-ERYQDDIKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMHTNN-ELFTTVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKRS-ESIDKVRQ-LLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRRVIKYEEQHHLLLYHTHP--MPKPRSYY 1724
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Human
Match: MED12 (mediator complex subunit 12 [Source:HGNC Symbol;Acc:HGNC:11957]) HSP 1 Score: 472.241 bits (1214), Expect = 3.300e-135 Identity = 481/1797 (26.77%), Postives = 801/1797 (44.57%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMR-------------NTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTNNKHPDRSITD-----------------------FYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRKS-------PELDRMSTGDNPDSVRSE---------------CSGLNQILPSIPIVDYR-----------------NFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYM-------------FDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSS-----SIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHV-VQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN---STAN--SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLR-----VLREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIK----------FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ ++I + N DT +RK V KD + +S+ I W L+ T P +L K++P F KKE+V + KY VP+ RA W IK++ + +E+ KK +VD +W + L E+L + + R + H+ E+ + +++Y +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + + L L + +++ C HR ++F LS ++ ++ L CP A+V++ GSPLD LP A S LP P G R + ++EQ I +R AVE +W SF+ E TA I V E+LD + + S+ + LC + L D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ D + ++ F NLV LF ELI ++FS N Y +I+RG A P PP F A + S P L D SV E C G P P V+ + RH+QY HFPIP + HE N R L+ + RD + ++++ KDI K+ ++G D+ + + RR R E+ AE I ++F+ L++YD V +Q + + ++ + LP + + +L+E YSL I + + ++ L+ + + + L+ + L+ SY + +CI+ L + + L+ D ++F G+ + ++ + S RC A + + SC+ L++ F K++N ++ N++P + ID +E+ F + S L N R+S V N L+HV V D D++ I + E LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S P RL IL LF Q N S N +V D +LL++S ++ + +LK + V D L+ + ++ S + ++ + +L VLR IC WV R + L D N L D +S++QA+ L+ +IC+P L + R NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE ++ + S + KP S+E + +L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q+ ++N ++ + + DD + K L+H ++K RL LVG +FD +Q S + +W +LL ++II G V+M S++ ELF TVLDM+S LI+ + I + + KKL+KE+ ++ + +E ++ LLP K T DVI P ++ ++ + K+G V K++I+PW++ EG+K LS WF V D V EE L++ H H RP YY
Sbjct: 19 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVSFN------PAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQ--KDNFWL-VTARSQSAINTWFTDLAGTKPLTQLA-KKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAISETKVKK--RHVDPFMEWTQIITKYLWEQLQKM-AEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGE-FVQSAYLSRRLAYFCTRRLALQLDGVSSHSSHVISAQSTSTLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRW---SFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPP-SPFDDPADDPEHKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIEGTLGVLYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAF---PTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFAL-------GMSYHLPLVQHVQFIFDLME----YSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKS-----LSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---IRCAAIPSLLNAACSEQDS------EPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELKGSGFTVTGGTEELPEEEGGGGSGGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLLDNEDGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTPNNEMNSLLENIAKATIEVFQQSAETGSSSGSTASNM----------PSSSKTKPVLSSLERSGVWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVHQIVNNWRDDQYL-DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAMLLLEIIISGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKLQKELGER-QSDSLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKPSAPLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRP--RPRAYY 1738
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Human
Match: MED12 (mediator complex subunit 12 [Source:HGNC Symbol;Acc:HGNC:11957]) HSP 1 Score: 472.241 bits (1214), Expect = 3.762e-135 Identity = 481/1797 (26.77%), Postives = 801/1797 (44.57%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMR-------------NTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTNNKHPDRSITD-----------------------FYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRKS-------PELDRMSTGDNPDSVRSE---------------CSGLNQILPSIPIVDYR-----------------NFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYM-------------FDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSS-----SIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHV-VQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN---STAN--SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLR-----VLREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIK----------FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ ++I + N DT +RK V KD + +S+ I W L+ T P +L K++P F KKE+V + KY VP+ RA W IK++ + +E+ KK +VD +W + L E+L + + R + H+ E+ + +++Y +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + + L L + +++ C HR ++F LS ++ ++ L CP A+V++ GSPLD LP A S LP P G R + ++EQ I +R AVE +W SF+ E TA I V E+LD + + S+ + LC + L D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ D + ++ F NLV LF ELI ++FS N Y +I+RG A P PP F A + S P L D SV E C G P P V+ + RH+QY HFPIP + HE N R L+ + RD + ++++ KDI K+ ++G D+ + + RR R E+ AE I ++F+ L++YD V +Q + + ++ + LP + + +L+E YSL I + + ++ L+ + + + L+ + L+ SY + +CI+ L + + L+ D ++F G+ + ++ + S RC A + + SC+ L++ F K++N ++ N++P + ID +E+ F + S L N R+S V N L+HV V D D++ I + E LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S P RL IL LF Q N S N +V D +LL++S ++ + +LK + V D L+ + ++ S + ++ + +L VLR IC WV R + L D N L D +S++QA+ L+ +IC+P L + R NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE ++ + S + KP S+E + +L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q+ ++N ++ + + DD + K L+H ++K RL LVG +FD +Q S + +W +LL ++II G V+M S++ ELF TVLDM+S LI+ + I + + KKL+KE+ ++ + +E ++ LLP K T DVI P ++ ++ + K+G V K++I+PW++ EG+K LS WF V D V EE L++ H H RP YY
Sbjct: 19 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVSFN------PAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQ--KDNFWL-VTARSQSAINTWFTDLAGTKPLTQLA-KKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAISETKVKK--RHVDPFMEWTQIITKYLWEQLQKM-AEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGE-FVQSAYLSRRLAYFCTRRLALQLDGVSSHSSHVISAQSTSTLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRW---SFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPP-SPFDDPADDPEHKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIEGTLGVLYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAF---PTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFAL-------GMSYHLPLVQHVQFIFDLME----YSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKS-----LSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---IRCAAIPSLLNAACSEQDS------EPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELKGSGFTVTGGTEELPEEEGGGGSGGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLLDNEDGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTPNNEMNSLLENIAKATIEVFQQSAETGSSSGSTASNM----------PSSSKTKPVLSSLERSGVWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVHQIVNNWRDDQYL-DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAMLLLEIIISGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKLQKELGER-QSDSLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKPSAPLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRP--RPRAYY 1738
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Human
Match: MED12 (mediator complex subunit 12 [Source:HGNC Symbol;Acc:HGNC:11957]) HSP 1 Score: 392.504 bits (1007), Expect = 8.039e-110 Identity = 426/1650 (25.82%), Postives = 721/1650 (43.70%), Query Frame = 2
Query: 545 RAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMR-------------NTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTNNKHPDRSITD-----------------------FYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRKS-------PELDRMSTGDNPDSVRSE---------------CSGLNQILPSIPIVDYR-----------------NFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYM-------------FDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSS-----SIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHV-VQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN---STAN--SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLR-----VLREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGI----------KFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
RA W IK++ + +E+ KK +VD +W + L E+L + + R + H+ E+ + +++Y +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + + L L + +++ C HR ++F LS ++ ++ L CP A+V++ GSPLD LP A S LP P G R + ++EQ I +R AVE +W SF+ E TA I V E+LD + + S+ + LC + L D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ D + ++ F NLV LF ELI ++FS N Y +I+RG A P PP F A + S P L D SV E C G P P V+ + RH+QY HFPIP + HE N R L+ + RD + ++++ KDI K+ ++G D+ + + RR R E+ AE I ++F+ L++YD V +Q + + ++ + LP + + +L+E YSL I + + ++ L+ + + + L+ + L+ SY + +CI+ L + + L+ D ++F G+ + ++ + S RC A + + SC+ L++ F K++N ++ N++P + ID +E+ F + S L N R+S V N L+HV V D D++ I + E LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S P RL IL LF Q N S N +V D +LL++S ++ + +LK + V D L+ + ++ S + ++ + +L VLR IC WV R + L D N L D +S++QA+ L+ +IC+P L + R NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE ++ + S + KP S+E + +L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q+ ++N ++ + + DD + K L+H ++K RL LVG +FD +Q S + +W +LL ++II G V+M S++ ELF TVLDM+S LI+ + I + + KKL+KE+ ++ + +E ++ LLP K T DVI P ++ ++ + K+G V K++I+PW++ EG+K LS WF V D V EE L++ H H RP YY
Sbjct: 2 RAAWLIKMTCAYYAAISETKVKK--RHVDPFMEWTQIITKYLWEQLQKM-AEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGE-FVQSAYLSRRLAYFCTRRLALQLDGVSSHSSHVISAQSTSTLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRW---SFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPP-SPFDDPADDPEHKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIEGTLGVLYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAF---PTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFAL-------GMSYHLPLVQHVQFIFDLME----YSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKS-----LSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---IRCAAIPSLLNAACSEQDS------EPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELKGSGFTVTGGTEELPEEEGGGGSGGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLLDNEDGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTPNNEMNSLLENIAKATIEVFQQSAETGSSSGSTASNM----------PSSSKTKPVLSSLERSGVWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVHQIVNNWRDDQYL-DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAMLLLEIIISGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKLQKELGER-QSDSLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKPSAPLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRP--RPRAYY 1585
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Human
Match: MED12L (mediator complex subunit 12L [Source:HGNC Symbol;Acc:HGNC:16050]) HSP 1 Score: 386.726 bits (992), Expect = 2.392e-108 Identity = 371/1368 (27.12%), Postives = 634/1368 (46.35%), Query Frame = 2
Query: 1226 RDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVV---------SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARG-LFESVANLPLPPIGGFLSVAHNXXXXXHRKSPELDRMSTGDNPDSVRSE--------CSGLNQILPSIPIVDYRNFN--RHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKL-ENVFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTII---VETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVC--PPIVPTTRLASYILFRLFTMEQQ----NSTANSVSAFKKE-DVNLLSSSLQKVTTELLVDLLKMLAVHSD------------------KGRLQDQDYFDL--TENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLI-DKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDT--MNRTFTNLNIWSLHFDQMKIQLLLTQIPEE-------ERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTE----SIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIH-TLFSIPNHGI---------KFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
R I ++EQ I QR AVE +W SF+ E TA I V E+LDR+ ++ S+ E L + + N ++ LLCEW+VS R+G HR VA++++ I + +S QN L+ FLDT++P + D + F NLV LF E I ++FS + YM +I+RG L + + P P+G A S H E+ G++ ++ + C L + ++ N++ RHLQY HFPIP+++ HE N R+ LY + RD + L+++ KDI K+ K+ + E +K+R++ +E +E ++ ++ + L+Y+D V SQ + + S ++ LP I + +L+E + N + LI + ++ L+ + + + L+ + SL SY + +CI+ L ++ S L+ D ++F G+ + ++ V S RC A + + SC+ LRS F K+ + ++ N+ P D +D++E+ +M+ L N R+S V N L++V C RIN I E + ++LS+EW+ + +L N G FN +L + +DL F+++++T IA ++ARQCF D + V +L + C P R+ +L LF Q +T + D +LL+++ + + +LK + + D +G D + D+ N S G +SI E + + + VLR IC WV +E P RL D LI D +SN QA+ LL +IC+P CT D + + R NL W+L +++QL++ Q ++ E ++++N++K I +F+ A+ N +N + + S RQ + S E +L+ LI +LP + + +++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL +Q+ + N +E E+ DD++ + ++H +++ RL LVG +FD +Q S + DW LLL ++I G V+MH+++ ELF TVLDM+ LI+ TL S ++ + ++KKL+KE+ DK + E ++ ++ LLP K T DVI P+ ++ ++ + KQG V K++++PW++ EG KN LS WF V D V+ EE +L++ H HP + +P +YY
Sbjct: 281 RARIYEVEQQIKQRGRAVEVRW---SFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSSSLAGSSLPVFQNVLLRFLDTQAPSLSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTRPRSPVG---ENADEHYSKDHDVKMEIFSPMPGESCENANTSLGRRMSVNCEKLVKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTETGVGDEG--QKARKNKQETFPTLE----TVFTKLQLLSYFDQHQVTSQISNNVLEQIT-------SFASGTSYHLPLAHHIQLIFDLMEPALNINGLI----DFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLG-----KILSDNAANRYSFVCNTLMNV--CMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSNHVWG-------FNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLL------AAACGDADAEPGARMTCRLLLHLFRAPQACFLPQATGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNSVSSLKNDDFTMRGLRCDGNADDIWTASQNPKSCG----KSISIETANLR----EYARYVLRTICQQEWVGEHCLKE-PERLCTDKELILDPVLSNMQAQKLLQLICYPHGI---KECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSADLN-NSSNSGMSLFNPNSIGSADTSSTRQNGIKTFLSSSERRGVWLVAPLIARLP-TSVQGRVLKAAGEELEKGQHLGS-SSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWRE-ERYQDDIKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMHTNN-ELFTTVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKRS-ESIDKVRQ-LLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRRVIKYEEQHHLLLYHTHP--MPKPRSYY 1584 HSP 2 Score: 114.39 bits (285), Expect = 1.630e-24 Identity = 82/255 (32.16%), Postives = 131/255 (51.37%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIR--IKLMRNTIDH------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQ 844
LGPPDVY Q+ KQKED LT NV++GFN ++P +EH SA++I + P + + + +++ + N QDT K+K V KD + +S+ I+ W L+ P + ++ K++P KKEDV + KY VP+ RA W IK++ + + +E+ KK R D +W R L E+L I + +T D E E + ++EY +L M+ E +L+ E L W++ E+
Sbjct: 19 LGPPDVYPQDPKQKEDELTAVNVKQGFN-NQPAFTGDEHGSARNI----VINP--SKIGAYFSSILAEKLKLNTFQDTGKKKPQVNA--KDNYWL-VTARSQSAIHSWFSDLAGNKPLS-ILAKKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKK-RQAPDPNLEWTQISTRYLREQLAKISDFYHMASSTGDGPVPVPPEVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEK 261
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Celegans
Match: dpy-22 (Mediator of RNA polymerase II transcription subunit 12 [Source:UniProtKB/Swiss-Prot;Acc:Q20497]) HSP 1 Score: 53.1434 bits (126), Expect = 2.667e-6 Identity = 67/312 (21.47%), Postives = 127/312 (40.71%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVVEEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPY---------AELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSL---------SDWVLSFIRTLNEKLDLIRIKLMRNTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC-----SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLL 976
+G DVY+Q Q+ED+LT +++G Y P+ + +E S F N ++ + + ++ +K + + IP + ++W LSD + + + +++RIP F +KE + E Y + RAIW +K+ + + +KK +V +L + W+++ + K RN I E T + + YL M M+D+ +LD E L L Q + ++ ++ + +YF + S +L R+ LC ++ L
Sbjct: 9 MGTADVYKQNKNQEEDMLTTERLKKG--YQMPLTQ---------YELQSLVFNASENKLIRLEKAQKRSQSMIASVIHKKGEFHMNYDRERKIPKEQLPCFAPHNWKRILSDRVKFFSALARGTPLQQLSQRIPGFRRKELLFLEFSDYNISYDRAIWCVKLLCILGFNSSSKTQKKTLLDVATLELSQACNKTTIWLVTQL-----------YKSFRNPIKRR-EATKT-WNYLTGFMKYMFDDGVLDKQEFLNDLTEVFNQLFLQKNFKNPSVLSTFMKYYVYFVEDLSSSLVLARRSSTLLCQALGFLF 296
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Fly
Match: kto (gene:FBgn0001324 transcript:FBtr0074884) HSP 1 Score: 140.198 bits (352), Expect = 1.279e-32 Identity = 136/517 (26.31%), Postives = 239/517 (46.23%), Query Frame = 2
Query: 3545 HMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQI--PEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHF-------CTHKNYQD---KENDLTKSS-------------LILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMP--DDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEE-HANLMIGHDHPDKLIRPDNYYTSFPEILPEDIK 5002
+ + F VL++IC V R + +++ID+ ++ QA+ +L++IC+P+ + D + R NL W+L + +QL+ Q E ++ V++ I++F + E+V +H+ KP S +L+ LI KL + +++ A + LES +F C D K N S+ + L Y PF+ L++ CL +D+ + L SL Q+ + + E + + D+ + + I +++ R +LVG +F+ IQ++ DW +LL++L+ GVV++ S + ELF TV+DM++TL+H+ + + + ++KKL+KEI +K N + +I+ LLP +K +VI H + K+ + K+RI+ W+++EG KN LS WF AV + L EE H NL H L++P +YY + PEDI+
Sbjct: 1410 QISLLEFAQAVLKQICAQEHVLERCLKNAEQLC---DMIIDEMLTAKQAQRVLHMICYPEPEF--NIISELDQRSMIVRILENLGQWTLRISWLDLQLMYRQSLSNNAELNVWLDTVARAAIDVF--------HMEEVVLPGAVKA--------THKPKP-------STWLVAPLIAKL-TPAVQGRILRVAGQVLESMNYFSKVSKSDCNSSGSGDEREKSNSCHSSNSYGLGGVPARNKKMPLDYQPFLGLILTCLKGQDEYKENLLVSLYAQLSQCLQSFAELDTIGGIDEPQAREEILDALQLRFSLVGGMFEAIQKNSTPTTDWAILLAQLVCQGVVDL-SCNRELFTTVVDMLATLVHSTL-VSDDERHYMNLMKKLKKEIGEK-NNASIRVIRQ-LLPLYKQPTEVIAC-----EHSGMDTKGNKICDIDKKQLRISDKQRISVWDILEGHKNPAPLSWVWFGAVKLERKPLTYEEAHRNLKY---HTHSLVKPSSYYYEPLPLPPEDIE 1885 HSP 2 Score: 112.464 bits (280), Expect = 4.080e-24 Identity = 118/513 (23.00%), Postives = 221/513 (43.08%), Query Frame = 2
Query: 1853 DNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEH----NLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRSCPTFVMNMKKLENV--FRNI--KPDKDRSSSIDYVESVGMDLFKINMVSCS------ENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVSNDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSI-VCPPIVPTTRLASYILFRLF-TMEQQNSTANSVS 3337
+ PDS + G + P I +RH Y HFPIP +D + + N R L+ + RD K +++++K+IGK++TK+ + D+ +K SR E E+ S+ + + Y+D V +QC + LN ++ +N +LP ++ L +L+E + N L+ + D +L+K + + Q + +L+ SY + + I+ L ++ S L+ + +F G+ R+ + + RC A + +SC L+ ++L+ + F++I P++ Y + +LF + E NV +S V N L+ V + TD ++L + E ++ ++LS EWI A+ S L G+ SP Y + + L + ++ + ++AR CF +DF+ + LA+ + + RL +++ +LF T+E SVS
Sbjct: 802 EAPDSPKIGPPGDGETNPGGSI------SRHYVYTKHFPIPQDDPSMSSYSSESNQRYILLFGVGKERDEKKHAVKKMSKEIGKLFTKK-FSIDVAAAGHVKKHSRN---------EFNFEATTSKCQQMAYFDQHVVTAQCAANVLEQLNGFAL-------GNNNYLPVQEHVAFLFDLMELALNIYSLLELCD----SLLKELPEVEHQLQLKKSNLVRSYTTSLALYIVSILRRYHSCLLLSPEQTLSVFEGVCRTIRHVSNPSECTSAERCIIAYLSDLHESCVLLQGKEQSTEYYQQLQCIKRFKDIFNTPEQLDLPPQGYNPLLLQELFMAPRRGGKLDPHWLGTLHESPANV---YSFVSNALIAVCRETDNERLNDVALACAELTASCNVLSEEWIYALQS-LCSGSKSPRYPHLGGQVD----IGQLKTHNALAVFVCILVARHCFSLADFVSKFALPTLARSVSAGGAELSVDAEAGARLTCHLVLKLFKTLEIPQPGMYSVS 1279 HSP 3 Score: 98.9821 bits (245), Expect = 4.743e-20 Identity = 103/409 (25.18%), Postives = 165/409 (40.34%), Query Frame = 2
Query: 749 FEYLMRLMVAMYDEDLLDHTEVLQWLV----STNEQCSDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTNNKHPDRSITDF-------------YAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNI---KIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLN-RDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAG---LIKVVELLDRYDYNCYKDSSVFEGLCTVVVSLVDNHSL----------------------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN---------IHQNQSHQS-----------------IQNCLVEFLDTKSPIIDSQISADSE--PFRNLVCLFGELIERELFSMNDYMSYMIARG--LFESV 1747
++Y +L MY+E LLD E L W++ Q S DE + K L F L + F +SE L RK+ + + + LL N ++I + E SC HR ++ LS ++ +++ECP A+V++ I + P L L N R + E I+ R+ E +W + + +AG V+ LD D +C+ + T+ + + ++ + +LCEW+VS R G HR +VA ++D Q S + Q+ L+ FLD +P++D +S+ + F NLV LF LI ++FS N YM +I+RG L ESV
Sbjct: 334 WKYCHQLSKYMYEESLLDRQEFLNWILDLLDKMRTQASFDEPLKKLVLSFALQYMHDFVQSERLCRKMAYIVSKKLAQLL-NTVVEQQTIKELDEPKLQQDPYELALQEQMSCPHHRDIVLYLSTILQIITIECPTALVWSGIAAHRAPSSLLGSPLDHLPLAPSVLPMPTRCPRTNHEIRRQLRAAESDIVLRTQHAEQRW------FAAKWLSAGKNQYTSVLATLDHLDTHCFDRMEHNNSIDTLYAQIFPSPTVSRRREEDQVEPRPPYEPKQDKDTVRILCEWAVSGQRWGEHRAMVVAILLDKRQIDVTSTPADQQSSDKDDKDSLASGAGLIDGLPVFQHVLMHFLDHDAPVLDEHVSSPQQRTEFTNLVQLFSALIRHDVFSHNAYMHTLISRGDLLLESV 735 HSP 4 Score: 92.0485 bits (227), Expect = 5.869e-18 Identity = 63/194 (32.47%), Postives = 96/194 (49.48%), Query Frame = 2
Query: 101 KVLLGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVVEEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKL 682
+ LGPPD+Y Q+ KQ+ED LT NV+ GF + P+ +E +A + S + ++ F V+ K DT ++K + KD P + K + W L+ P L KR P F+KKE++ + + QV + RA WFIK+SA + ES KK RS D ++W + I+ + E L
Sbjct: 13 RTRLGPPDIYPQDAKQREDELTPTNVKHGFTTTPPLSDEFGTAHN------SNVNASKVSAFFSGVLAKKEELMTLPDTGRKKQQINC--KD-NFWPVSPRRKCTVDAWFKDLAGNKPLLSLA-KRAPSFNKKEEIFITLCENQVNMQRATWFIKLSAAYTLSFTESKNKK-RSIYDPAAEWTGNMIKFMKELL 195
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Zebrafish
Match: med12 (mediator complex subunit 12 [Source:NCBI gene;Acc:566632]) HSP 1 Score: 503.442 bits (1295), Expect = 1.272e-145 Identity = 514/1821 (28.23%), Postives = 834/1821 (45.80%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVS-AMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDH-----------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTNNK---------------------------------HPDRSITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPIIDSQISADSE--PFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXX-----------XHRKSPELDRMSTGDNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIV---ETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNSTANSVSAFKKE--------DVNLLSSSLQKVTTELLVDLLKMLAVHSD-----KGRLQDQDYFDLTENNQVSFGPPFRR-SIDTEESFIHMKIWNFTLRVLREICCVSWV--RIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLF----------SIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPD--NYYTSFPEILPEDIKDPSISDPME 5029
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F ++ ++I + N DT KRK V KD + +S+ I +W L+ T P +L K++P F KKE+V + KY VP+ R+ W IK++ A HA I NK K R +D +W + L E+L + + R + E E + ++EY +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + +NLLL++ P TDFY C HR V+F LS ++ S+ L CP A+V++ N GSPLDLLP A S LP P G N R + ++E+ I +R AVE +W SF+ E TA I V E+LD + + S+ + L + D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ ++ +SE F NLV LF ELI ++FS N YM +I+RG S ++LP P + + + HNSS++ + SP ++ + S + G++ P+ P+V Y RH+QY HFPIP + HE N R LY + RD + ++++ KDI K+ ++ + + RK+S+ + AE I S+F+ L+++D V SQ + + ++ + LP I + +L+E S N S LI + LN + L+E + L+ + +L SY + +CI+ L ++ S L+ D ++F G+ ++ ++ V+ RC A + + SC+ L+S F K++N ++ NI P D+ ID + + +M+ N EL + R+S V N L+ V C D R+N I + E + LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D V CVA+ A +Q S P RL IL LF Q+N + K D +LL++S + + +LK + + D G D+ E++ S R SI+T ++ K VL+ IC WV R S S ++D VL+ N QA+ LL +IC+P L + + R N++ W++ +++QL++ Q E ++EN++K I +F+ AE ++ + +S S + S E + +L+ LI KLP + + ++ AA E+LE G+H + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + K ++H ++K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ S+ + + ++KKLRKE+ D+ + E +E ++ LLP K T DVI P ++ ++ EK G Q V K++I+PW+V EG+K+ LS WF + D V EE L++ H H I+P +YY + P LP++ ++P P E
Sbjct: 20 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVNFNSSKI------SSNFSSIIAEKLRCNTFPDTGKRKPQVNQ--KDNFWL-VTARSQSSINNWFTDLAGTKPLTQLA-KKVPIFSKKEEVFGYLAKYSVPVMRSAWMIKMTCAYHAAI--TENKMKKRHVIDPCIEWTQIITKYLWEQLQKV-AEFYRQSPSQGCGSPLPAPPAEVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLRLLLPLLLQYSGE-FVQSAYLSRRLAYFCTRRLNLLLSDGSIGPGPGGHQAHGISAQQGNALPPTPTSQPAGGNQPQTPFTDFYI----CPQHRPVVFGLSCMLQSIVLCCPSALVWHYSLTDSRNKTGSPLDLLPIAPSNLPMPGGNSTFNQQVRAKVREIEEQIKERGQAVEFRW---SFDKCQETTAGFTISRVLHTLEVLDNHSFEKSDFSNSLDSLYNRIFGSGQSKDGHEMSPDDDAVVTLLCEWAVSCKRSGPHRAMVVAKLLEKRQTEIEAERCGESEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPVL-TEPGNESERVEFSNLVLLFYELIRHDVFSHNIYMCTLISRGDLASNSHLPRPRSPSDEPSDESERKDQDAGSSVKIEDTGMSESMEIDHNSSANFDEMFSPPMHCESKGSPSPEKQAQEQESKSTAKD-KGMD---PAFPLV-YEQ-PRHIQYATHFPIPQEESASHECNQRLVVLYGVGKQRDEARHAIKKITKDILKVLNRKSTAETGGEEGQKRKRSKPE-------AFPTAEDIFSKFQHLSHFDQHQVTSQVSRNVLEQITSFAL-------GMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQL-LNELSLVE---AELLLKSSNLAGSYTTGLCLCIVAVLRRYHSCLILNPDQTAQVFDGLRIVVKSGVNPADCSSAERCILAYLYDLYTSCSHLKSKFGEIFSEFCSKVKNSIYYNIDPSDSNMLWDQMFMIDAITNPTAHNLNHSMLGKITN--ELNDSPANRYSFVCNVLMDV--CVDHRDPERVNDIGILCAELTAYCRSLSAEWLGVLKALCCSSNNG------NCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---VRCVAIPSLLNAACSEQDS------EPGARLTCRILLHLFRTPQRNPCPQDGTKSDKSIVGIRSSCDRHLLAASQNSIVVGAVFAVLKAVFMLGDAELKGSGFSHPAGLDDIGEDDMGSKKSGGRNVSIETASLVVYAKY------VLKSICHQEWVGERCLKSLSEDSSALQDPVLV-----NIQAQRLLQLICYPHRQL-DSEEGDNPQRQRIKRILQNMDQWTMRQSSLELQLMIKQSSNNELYSLLENIAKATIEVFQKSAEMNSSNPSWNGSAVSGSSVSNSNSASKLKPVLSSSERSGVWLVAPLIGKLP-TSVQGHVLKAAGEELEKGQHLGP-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWRE-DQYQDDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQS-ESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFEKEGLQ---VSTKQKISPWDVFEGLKHSAPLSWGWFGTIRVDRKVTKFEEQQRLLLYHTH----IKPKQRSYYLA-PLNLPQEEEEPLTPVPPE 1748
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Zebrafish
Match: med12 (mediator complex subunit 12 [Source:NCBI gene;Acc:566632]) HSP 1 Score: 503.056 bits (1294), Expect = 1.864e-145 Identity = 514/1821 (28.23%), Postives = 834/1821 (45.80%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVS-AMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDH-----------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTNNK---------------------------------HPDRSITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPIIDSQISADSE--PFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXX-----------XHRKSPELDRMSTGDNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIV---ETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNSTANSVSAFKKE--------DVNLLSSSLQKVTTELLVDLLKMLAVHSD-----KGRLQDQDYFDLTENNQVSFGPPFRR-SIDTEESFIHMKIWNFTLRVLREICCVSWV--RIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLF----------SIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPD--NYYTSFPEILPEDIKDPSISDPME 5029
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F ++ ++I + N DT KRK V KD + +S+ I +W L+ T P +L K++P F KKE+V + KY VP+ R+ W IK++ A HA I NK K R +D +W + L E+L + + R + E E + ++EY +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + +NLLL++ P TDFY C HR V+F LS ++ S+ L CP A+V++ N GSPLDLLP A S LP P G N R + ++E+ I +R AVE +W SF+ E TA I V E+LD + + S+ + L + D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ ++ +SE F NLV LF ELI ++FS N YM +I+RG S ++LP P + + + HNSS++ + SP ++ + S + G++ P+ P+V Y RH+QY HFPIP + HE N R LY + RD + ++++ KDI K+ ++ + + RK+S+ + AE I S+F+ L+++D V SQ + + ++ + LP I + +L+E S N S LI + LN + L+E + L+ + +L SY + +CI+ L ++ S L+ D ++F G+ ++ ++ V+ RC A + + SC+ L+S F K++N ++ NI P D+ ID + + +M+ N EL + R+S V N L+ V C D R+N I + E + LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D V CVA+ A +Q S P RL IL LF Q+N + K D +LL++S + + +LK + + D G D+ E++ S R SI+T ++ K VL+ IC WV R S S ++D VL+ N QA+ LL +IC+P L + + R N++ W++ +++QL++ Q E ++EN++K I +F+ AE ++ + +S S + S E + +L+ LI KLP + + ++ AA E+LE G+H + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + K ++H ++K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ S+ + + ++KKLRKE+ D+ + E +E ++ LLP K T DVI P ++ ++ EK G Q V K++I+PW+V EG+K+ LS WF + D V EE L++ H H I+P +YY + P LP++ ++P P E
Sbjct: 20 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVNFNSSKI------SSNFSSIIAEKLRCNTFPDTGKRKPQVNQ--KDNFWL-VTARSQSSINNWFTDLAGTKPLTQLA-KKVPIFSKKEEVFGYLAKYSVPVMRSAWMIKMTCAYHAAI--TENKMKKRHVIDPCIEWTQIITKYLWEQLQKV-AEFYRQSPSQGCGSPLPAPPAEVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLRLLLPLLLQYSGE-FVQSAYLSRRLAYFCTRRLNLLLSDGSIGPGPGGHQAHGISAQQGNALPPTPTSQPAGGNQPQTPFTDFYI----CPQHRPVVFGLSCMLQSIVLCCPSALVWHYSLTDSRNKTGSPLDLLPIAPSNLPMPGGNSTFNQQVRAKVREIEEQIKERGQAVEFRW---SFDKCQETTAGFTISRVLHTLEVLDNHSFEKSDFSNSLDSLYNRIFGSGQSKDGHEMSPDDDAVVTLLCEWAVSCKRSGPHRAMVVAKLLEKRQTEIEAERCGESEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPVL-TEPGNESERVEFSNLVLLFYELIRHDVFSHNIYMCTLISRGDLASNSHLPRPRSPSDEPSDESERKDQDAGSSVKIEDTGMSESMEIDHNSSANFDEMFSPPMHCESKGSPSPEKQAQEQESKSTAKD-KGMD---PAFPLV-YEQ-PRHIQYATHFPIPQEESASHECNQRLVVLYGVGKQRDEARHAIKKITKDILKVLNRKSTAETGGEEGQKRKRSKPE-------AFPTAEDIFSKFQHLSHFDQHQVTSQVSRNVLEQITSFAL-------GMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQL-LNELSLVE---AELLLKSSNLAGSYTTGLCLCIVAVLRRYHSCLILNPDQTAQVFDGLRIVVKSGVNPADCSSAERCILAYLYDLYTSCSHLKSKFGEIFSEFCSKVKNSIYYNIDPSDSNMLWDQMFMIDAITNPTAHNLNHSMLGKITN--ELNDSPANRYSFVCNVLMDV--CVDHRDPERVNDIGILCAELTAYCRSLSAEWLGVLKALCCSSNNG------NCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---VRCVAIPSLLNAACSEQDS------EPGARLTCRILLHLFRTPQRNPCPQDGTKSDKSIVGIRSSCDRHLLAASQNSIVVGAVFAVLKAVFMLGDAELKGSGFSHPAGLDDIGEDDMGSKKSGGRNVSIETASLVVYAKY------VLKSICHQEWVGERCLKSLSEDSSALQDPVLV-----NIQAQRLLQLICYPHRQL-DSEEGDNPQRQRIKRILQNMDQWTMRQSSLELQLMIKQSSNNELYSLLENIAKATIEVFQKSAEMNSSNPSWNGSAVSGSSVSNSNSASKLKPVLSSSERSGVWLVAPLIGKLP-TSVQGHVLKAAGEELEKGQHLGP-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWRE-DQYQDDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQS-ESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFEKEGLQ---VSTKQKISPWDVFEGLKHSAPLSWGWFGTIRVDRKVTKFEEQQRLLLYHTH----IKPKQRSYYLA-PLNLPQEEEEPLTPVPPE 1748
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Zebrafish
Match: med12 (mediator complex subunit 12 [Source:NCBI gene;Acc:566632]) HSP 1 Score: 503.056 bits (1294), Expect = 1.864e-145 Identity = 514/1821 (28.23%), Postives = 834/1821 (45.80%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVS-AMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDH-----------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTNNK---------------------------------HPDRSITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPIIDSQISADSE--PFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXX-----------XHRKSPELDRMSTGDNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIV---ETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNSTANSVSAFKKE--------DVNLLSSSLQKVTTELLVDLLKMLAVHSD-----KGRLQDQDYFDLTENNQVSFGPPFRR-SIDTEESFIHMKIWNFTLRVLREICCVSWV--RIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLF----------SIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPD--NYYTSFPEILPEDIKDPSISDPME 5029
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F ++ ++I + N DT KRK V KD + +S+ I +W L+ T P +L K++P F KKE+V + KY VP+ R+ W IK++ A HA I NK K R +D +W + L E+L + + R + E E + ++EY +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + +NLLL++ P TDFY C HR V+F LS ++ S+ L CP A+V++ N GSPLDLLP A S LP P G N R + ++E+ I +R AVE +W SF+ E TA I V E+LD + + S+ + L + D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ ++ +SE F NLV LF ELI ++FS N YM +I+RG S ++LP P + + + HNSS++ + SP ++ + S + G++ P+ P+V Y RH+QY HFPIP + HE N R LY + RD + ++++ KDI K+ ++ + + RK+S+ + AE I S+F+ L+++D V SQ + + ++ + LP I + +L+E S N S LI + LN + L+E + L+ + +L SY + +CI+ L ++ S L+ D ++F G+ ++ ++ V+ RC A + + SC+ L+S F K++N ++ NI P D+ ID + + +M+ N EL + R+S V N L+ V C D R+N I + E + LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D V CVA+ A +Q S P RL IL LF Q+N + K D +LL++S + + +LK + + D G D+ E++ S R SI+T ++ K VL+ IC WV R S S ++D VL+ N QA+ LL +IC+P L + + R N++ W++ +++QL++ Q E ++EN++K I +F+ AE ++ + +S S + S E + +L+ LI KLP + + ++ AA E+LE G+H + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + K ++H ++K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ S+ + + ++KKLRKE+ D+ + E +E ++ LLP K T DVI P ++ ++ EK G Q V K++I+PW+V EG+K+ LS WF + D V EE L++ H H I+P +YY + P LP++ ++P P E
Sbjct: 20 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVNFNSSKI------SSNFSSIIAEKLRCNTFPDTGKRKPQVNQ--KDNFWL-VTARSQSSINNWFTDLAGTKPLTQLA-KKVPIFSKKEEVFGYLAKYSVPVMRSAWMIKMTCAYHAAI--TENKMKKRHVIDPCIEWTQIITKYLWEQLQKV-AEFYRQSPSQGCGSPLPAPPAEVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLRLLLPLLLQYSGE-FVQSAYLSRRLAYFCTRRLNLLLSDGSIGPGPGGHQAHGISAQQGNALPPTPTSQPAGGNQPQTPFTDFYI----CPQHRPVVFGLSCMLQSIVLCCPSALVWHYSLTDSRNKTGSPLDLLPIAPSNLPMPGGNSTFNQQVRAKVREIEEQIKERGQAVEFRW---SFDKCQETTAGFTISRVLHTLEVLDNHSFEKSDFSNSLDSLYNRIFGSGQSKDGHEMSPDDDAVVTLLCEWAVSCKRSGPHRAMVVAKLLEKRQTEIEAERCGESEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPVL-TEPGNESERVEFSNLVLLFYELIRHDVFSHNIYMCTLISRGDLASNSHLPRPRSPSDEPSDESERKDQDAGSSVKIEDTGMSESMEIDHNSSANFDEMFSPPMHCESKGSPSPEKQAQEQESKSTAKD-KGMD---PAFPLV-YEQ-PRHIQYATHFPIPQEESASHECNQRLVVLYGVGKQRDEARHAIKKITKDILKVLNRKSTAETGGEEGQKRKRSKPE-------AFPTAEDIFSKFQHLSHFDQHQVTSQVSRNVLEQITSFAL-------GMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQL-LNELSLVE---AELLLKSSNLAGSYTTGLCLCIVAVLRRYHSCLILNPDQTAQVFDGLRIVVKSGVNPADCSSAERCILAYLYDLYTSCSHLKSKFGEIFSEFCSKVKNSIYYNIDPSDSNMLWDQMFMIDAITNPTAHNLNHSMLGKITN--ELNDSPANRYSFVCNVLMDV--CVDHRDPERVNDIGILCAELTAYCRSLSAEWLGVLKALCCSSNNG------NCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---VRCVAIPSLLNAACSEQDS------EPGARLTCRILLHLFRTPQRNPCPQDGTKSDKSIVGIRSSCDRHLLAASQNSIVVGAVFAVLKAVFMLGDAELKGSGFSHPAGLDDIGEDDMGSKKSGGRNVSIETASLVVYAKY------VLKSICHQEWVGERCLKSLSEDSSALQDPVLV-----NIQAQRLLQLICYPHRQL-DSEEGDNPQRQRIKRILQNMDQWTMRQSSLELQLMIKQSSNNELYSLLENIAKATIEVFQKSAEMNSSNPSWNGSAVSGSSVSNSNSASKLKPVLSSSERSGVWLVAPLIGKLP-TSVQGHVLKAAGEELEKGQHLGP-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWRE-DQYQDDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQS-ESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFEKEGLQ---VSTKQKISPWDVFEGLKHSAPLSWGWFGTIRVDRKVTKFEEQQRLLLYHTH----IKPKQRSYYLA-PLNLPQEEEEPLTPVPPE 1748
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Xenopus
Match: ENSXETT00000020345.1 (mediator complex subunit 12 [Source:NCBI gene;Acc:100495585]) HSP 1 Score: 478.019 bits (1229), Expect = 3.080e-137 Identity = 479/1767 (27.11%), Postives = 795/1767 (44.99%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKL----DLIRIKLM-----RNTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQCSDDE-QMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNS--VNLLLTNNKHPDRSIT----------------------DFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVY------NNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAA----GLIKVVELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS----------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXXXHRKSPELDRMSTGDNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSSSIDYVESVGMDLF---KINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCT-DVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN-----STANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGP-PFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIK----------FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ +++ + N DT +RK V KD + + +++ I W L+ T P L K++P F KKE+V + ++ VP+ RA W IK++ + E+ KK R +D + +W R L E+L D R L + E E+ + ++EY +L + M+ + +LD E L W++ E+ E +++K LP LL + + +S L+R+L + C LL + HP +T +++ C HR ++F LS ++ S+ L CP A+V+ N IK G L+ P+ + Q+ R + +EQ I +R +VE +W SF+ E TA ++ +E+LD + + S+ + L + L D H + ++ LLCEW+VS R G HR +VA++++ I + S Q L++FLDT++P++ D ++ F NLV LF ELI ++FS N YM +I+RG + P P + + + H S S E D +R GLN P + D RH+QY HFPIP + HE N R LY R RD + ++R+ +DI K+ ++ + K + RR + E+ AE I RF+ L+++D V +Q N L + A L + LP I + +L+E S N S LI + ++ L+ + + + L+ + SL+ SY +CI+ L + + L+ + ++F G+ + ++ + S RC A + + SC+ L+S F K++N ++ N++P S++ + + +D + V+C L + R+S V N L+HV D D++ I + E + LS+EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S RL IL LF Q N + +V D +LL++S ++ + +LK + V D L+ + T + S RR+ S + + VLR IC WV R + L D N L D +S++QA+ L+ +IC+P L T + NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE N + + + KP S+E + A+L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + L+H +K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ + I + ++KKLRKE+ D+ E +E ++ LLP K T DVI P ++ ++ + K+G V K++I+PW++ EGIK LS WF V D V +EE L++ H H +P +YY
Sbjct: 19 LGPPDVYPQDAKQKEDELTALNVKQGFN-NQPAVSADEHGSAKNVNFN------PAKISSNFSSIMSEKLRCNTLPDTGRRKPQVNQ--KDNFMLVTV-RTQSSINTWFSDLAGTKPLTHLA-KKVPIFGKKEEVFGFLARFSVPVMRAAWLIKMTCAYYAAITETKVKK-RHVMDPIIEWTQIITRYLWEQLQKIADYYRPALGGCSSPSGPMPPEVEVALKQWEYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRQGEDELLKLLLPLLLRYSNSLVQSAYLSRRLAY-FCTRRLAQLLEGSGSHPGHLMTAQTGTALPPAPAPPPPSGSAPSSPFSDLLQCPQHRPLVFGLSCMLQSIVLCCPSALVWHYSLTDNRIKT-GSPLDHLPIAPSSLPMPGGSSAFTQQV---RRKLRDMEQQIKERGRSVEVRW---SFDKCQEATAGFPIGRVLHTLEVLDSHSFEKSDFSNNLDSLYNRIFGLGLGKDGHEISPDDDAVVTLLCEWAVSCKRYGHHRALVVAKLLEKRQAEIEAERCGDSEAVDEKGSVSSGSLSALSAPPVFQEVLLQFLDTQAPMLTDPANESERVEFYNLVLLFCELIRHDVFSHNMYMCTLISRGDLGIDPHAPRPRSPYEDPSDDTDRKEGEANSSIKLEDTTLSETMDIDHGSGMFSPAMRCEGRSPGPEDGDRDIRRTVKGLNGEGPLSALYDQ---PRHIQYATHFPIPQEESCSHECNQRLVVLYGVGRQRDDARHIIKRITRDILKVLNRK----STSETGKVVGQRRRRAKPEAF---PTAEEIFCRFQQLSHFDQHQVTAQ---VSRNVLEQITSFALGL----SYHLPLVQHIQFIFDLMEYSLNISGLI----DFAIQLLNELSVVEAELLLKSSSLVGSYTMGLCLCIVAVLRHYHTCLILNQEQTAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPS---DSNMLWEQEFMLDTIINPSGHSVNCGMLGKLLSDSPTNRYSFVCNALVHVCAGDHDTDRVNDIAILCAELTGSCKALSSEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILVARQCLLLEDL---IRCAAIPSLLNAACSEQDSEA------GARLTCRILLHLFKTPQLNPCEPDGSKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELRGSGFSHPTGTDNASEEDIATRRAGGRPVSIETASLDEYAKYVLRSICQQEWVGERCVRS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLNDTEQGDNPQRQRIKHILQNLDQWTMRQSALELQLMIKQTPSNEMNSLLENIAKATIEVFQQSAENACAAPANSAALSNATSSNA--PPNSKTKPVLSSLERSGAWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYGQVQQIVSNWRE-DQYQDDCKTPQLLHDVLKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDR-QSESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGIKQSAPLSWGWFGTVRVDRRVSRMEEQQRLLLYHTHLKP--KPRSYY 1710
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Xenopus
Match: ENSXETT00000034172.1 (mediator complex subunit 12 [Source:NCBI gene;Acc:100495585]) HSP 1 Score: 475.707 bits (1223), Expect = 1.697e-136 Identity = 479/1779 (26.93%), Postives = 797/1779 (44.80%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKL----DLIRIKLM-----RNTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQCSDDE-QMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNS--VNLLLTNNKHPDRSIT----------------------DFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVY------NNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTA----AGLIKVVELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS----------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXXXHRK--------SPELDRMSTGDNPD----SVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSSSIDYVESVGMDLF---KINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCT-DVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN-----STANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGP-PFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIK----------FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ +++ + N DT +RK V KD + + +++ I W L+ T P L K++P F KKE+V + ++ VP+ RA W IK++ + E+ KK R +D + +W R L E+L D R L + E E+ + ++EY +L + M+ + +LD E L W++ E+ E +++K LP LL + + +S L+R+L + C LL + HP +T +++ C HR ++F LS ++ S+ L CP A+V+ N IK G L+ P+ + Q+ R + +EQ I +R +VE +W SF+ E TA ++ +E+LD + + S+ + L + L D H + ++ LLCEW+VS R G HR +VA++++ I + S Q L++FLDT++P++ D ++ F NLV LF ELI ++FS N YM +I+RG + P P + + + H S + SP + P+ +R GLN P + D RH+QY HFPIP + HE N R LY R RD + ++R+ +DI K+ ++ E + RR + E+ AE I RF+ L+++D V +Q N L + A L + LP I + +L+E S N S LI + ++ L+ + + + L+ + SL+ SY +CI+ L + + L+ + ++F G+ + ++ + S RC A + + SC+ L+S F K++N ++ N++P S++ + + +D + V+C L + R+S V N L+HV D D++ I + E + LS+EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S RL IL LF Q N + +V D +LL++S ++ + +LK + V D L+ + T + S RR+ S + + VLR IC WV R + L D N L D +S++QA+ L+ +IC+P L T + NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE N + + + KP S+E + A+L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + L+H +K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ + I + ++KKLRKE+ D+ E +E ++ LLP K T DVI P ++ ++ + K+G V K++I+PW++ EGIK LS WF V D V +EE L++ H H +P +YY
Sbjct: 19 LGPPDVYPQDAKQKEDELTALNVKQGFN-NQPAVSADEHGSAKNVNFN------PAKISSNFSSIMSEKLRCNTLPDTGRRKPQVNQ--KDNFMLVTV-RTQSSINTWFSDLAGTKPLTHLA-KKVPIFGKKEEVFGFLARFSVPVMRAAWLIKMTCAYYAAITETKVKK-RHVMDPIIEWTQIITRYLWEQLQKIADYYRPALGGCSSPSGPMPPEVEVALKQWEYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRQGEDELLKLLLPLLLRYSNSLVQSAYLSRRLAY-FCTRRLAQLLEGSGSHPGHLMTAQTGTALPPAPAPPPPSGSAPSSPFSDLLQCPQHRPLVFGLSCMLQSIVLCCPSALVWHYSLTDNRIKT-GSPLDHLPIAPSSLPMPGGSSAFTQQ---VRRKLRDMEQQIKERGRSVEVRW---SFDKCQEATAGFPIGRVLHTLEVLDSHSFEKSDFSNNLDSLYNRIFGLGLGKDGHEISPDDDAVVTLLCEWAVSCKRYGHHRALVVAKLLEKRQAEIEAERCGDSEAVDEKGSVSSGSLSALSAPPVFQEVLLQFLDTQAPMLTDPANESERVEFYNLVLLFCELIRHDVFSHNMYMCTLISRGDLGIDPHAPRPRSPYEDPSDDTDRKEGEANSSIKLEDTTLSETMDIDHGSGALFEDMEKSEFPMFSPAMRCEGRSPGPEDGDRDIRRTVKGLNGEGPLSALYDQ---PRHIQYATHFPIPQEESCSHECNQRLVVLYGVGRQRDDARHIIKRITRDILKVLNRKSTS------ETDEGQRRRRAKPEAF---PTAEEIFCRFQQLSHFDQHQVTAQ---VSRNVLEQITSFALGL----SYHLPLVQHIQFIFDLMEYSLNISGLI----DFAIQLLNELSVVEAELLLKSSSLVGSYTMGLCLCIVAVLRHYHTCLILNQEQTAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPS---DSNMLWEQEFMLDTIINPSGHSVNCGMLGKLLSDSPTNRYSFVCNALVHVCAGDHDTDRVNDIAILCAELTGSCKALSSEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILVARQCLLLEDL---IRCAAIPSLLNAACSEQDSEA------GARLTCRILLHLFKTPQLNPCEPDGSKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELRGSGFSHPTGTDNASEEDIATRRAGGRPVSIETASLDEYAKYVLRSICQQEWVGERCVRS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLNDTEQGDNPQRQRIKHILQNLDQWTMRQSALELQLMIKQTPSNEMNSLLENIAKATIEVFQQSAENACAAPANSAALSNATSSNA--PPNSKTKPVLSSLERSGAWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYGQVQQIVSNWRE-DQYQDDCKTPQLLHDVLKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDR-QSESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGIKQSAPLSWGWFGTVRVDRRVSRMEEQQRLLLYHTHLKP--KPRSYY 1720
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Xenopus
Match: ENSXETT00000020359.1 (mediator complex subunit 12 [Source:NCBI gene;Acc:100495585]) HSP 1 Score: 473.011 bits (1216), Expect = 1.264e-135 Identity = 483/1801 (26.82%), Postives = 802/1801 (44.53%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKL----DLIRIKLM-----RNTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQCSDDE-QMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNS--VNLLLTNNKHPDRSIT----------------------DFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVY------NNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTA----AGLIKVVELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS----------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXXXHRK--------SPELDRMSTGDNPD----SVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRG--------YMFDIIQIEKS--------------RKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSSSIDYVESVGMDLF---KINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCT-DVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN-----STANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGP-PFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIK----------FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ +++ + N DT +RK V KD + + +++ I W L+ T P L K++P F KKE+V + ++ VP+ RA W IK++ + E+ KK R +D + +W R L E+L D R L + E E+ + ++EY +L + M+ + +LD E L W++ E+ E +++K LP LL + + +S L+R+L + C LL + HP +T +++ C HR ++F LS ++ S+ L CP A+V+ N IK G L+ P+ + Q+ R + +EQ I +R +VE +W SF+ E TA ++ +E+LD + + S+ + L + L D H + ++ LLCEW+VS R G HR +VA++++ I + S Q L++FLDT++P++ D ++ F NLV LF ELI ++FS N YM +I+RG + P P + + + H S + SP + P+ +R GLN P + D RH+QY HFPIP + HE N R LY R RD + ++R+ +DI K+ ++ M + QIEK + RR + E+ AE I RF+ L+++D V +Q N L + A L + LP I + +L+E S N S LI + ++ L+ + + + L+ + SL+ SY +CI+ L + + L+ + ++F G+ + ++ + S RC A + + SC+ L+S F K++N ++ N++P S++ + + +D + V+C L + R+S V N L+HV D D++ I + E + LS+EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S RL IL LF Q N + +V D +LL++S ++ + +LK + V D L+ + T + S RR+ S + + VLR IC WV R + L D N L D +S++QA+ L+ +IC+P L T + NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE N + + + KP S+E + A+L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + L+H +K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ + I + ++KKLRKE+ D+ E +E ++ LLP K T DVI P ++ ++ + K+G V K++I+PW++ EGIK LS WF V D V +EE L++ H H +P +YY
Sbjct: 19 LGPPDVYPQDAKQKEDELTALNVKQGFN-NQPAVSADEHGSAKNVNFN------PAKISSNFSSIMSEKLRCNTLPDTGRRKPQVNQ--KDNFMLVTV-RTQSSINTWFSDLAGTKPLTHLA-KKVPIFGKKEEVFGFLARFSVPVMRAAWLIKMTCAYYAAITETKVKK-RHVMDPIIEWTQIITRYLWEQLQKIADYYRPALGGCSSPSGPMPPEVEVALKQWEYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRQGEDELLKLLLPLLLRYSNSLVQSAYLSRRLAY-FCTRRLAQLLEGSGSHPGHLMTAQTGTALPPAPAPPPPSGSAPSSPFSDLLQCPQHRPLVFGLSCMLQSIVLCCPSALVWHYSLTDNRIKT-GSPLDHLPIAPSSLPMPGGSSAFTQQ---VRRKLRDMEQQIKERGRSVEVRW---SFDKCQEATAGFPIGRVLHTLEVLDSHSFEKSDFSNNLDSLYNRIFGLGLGKDGHEISPDDDAVVTLLCEWAVSCKRYGHHRALVVAKLLEKRQAEIEAERCGDSEAVDEKGSVSSGSLSALSAPPVFQEVLLQFLDTQAPMLTDPANESERVEFYNLVLLFCELIRHDVFSHNMYMCTLISRGDLGIDPHAPRPRSPYEDPSDDTDRKEGEANSSIKLEDTTLSETMDIDHGSGALFEDMEKSEFPMFSPAMRCEGRSPGPEDGDRDIRRTVKGLNGEGPLSALYDQ---PRHIQYATHFPIPQEESCSHECNQRLVVLYGVGRQRDDARHIIKRITRDILKVLNRKSTSETGKVVVMGKVKQIEKQVNVPKLTLSPCGTDEGQRRRRAKPEAF---PTAEEIFCRFQQLSHFDQHQVTAQ---VSRNVLEQITSFALGL----SYHLPLVQHIQFIFDLMEYSLNISGLI----DFAIQLLNELSVVEAELLLKSSSLVGSYTMGLCLCIVAVLRHYHTCLILNQEQTAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPS---DSNMLWEQEFMLDTIINPSGHSVNCGMLGKLLSDSPTNRYSFVCNALVHVCAGDHDTDRVNDIAILCAELTGSCKALSSEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILVARQCLLLEDL---IRCAAIPSLLNAACSEQDSEA------GARLTCRILLHLFKTPQLNPCEPDGSKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELRGSGFSHPTGTDNASEEDIATRRAGGRPVSIETASLDEYAKYVLRSICQQEWVGERCVRS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLNDTEQGDNPQRQRIKHILQNLDQWTMRQSALELQLMIKQTPSNEMNSLLENIAKATIEVFQQSAENACAAPANSAALSNATSSNA--PPNSKTKPVLSSLERSGAWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYGQVQQIVSNWRE-DQYQDDCKTPQLLHDVLKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDR-QSESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGIKQSAPLSWGWFGTVRVDRRVSRMEEQQRLLLYHTHLKP--KPRSYY 1748
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Xenopus
Match: ENSXETT00000034146.1 (mediator complex subunit 12 [Source:NCBI gene;Acc:100495585]) HSP 1 Score: 472.241 bits (1214), Expect = 1.765e-135 Identity = 483/1801 (26.82%), Postives = 802/1801 (44.53%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKL----DLIRIKLM-----RNTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQCSDDE-QMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNS--VNLLLTNNKHPDRSIT----------------------DFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVY------NNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTA----AGLIKVVELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS----------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXXXHRK--------SPELDRMSTGDNPD----SVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRG--------YMFDIIQIEKS--------------RKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSSSIDYVESVGMDLF---KINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCT-DVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN-----STANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGP-PFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIK----------FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ +++ + N DT +RK V KD + + +++ I W L+ T P L K++P F KKE+V + ++ VP+ RA W IK++ + E+ KK R +D + +W R L E+L D R L + E E+ + ++EY +L + M+ + +LD E L W++ E+ E +++K LP LL + + +S L+R+L + C LL + HP +T +++ C HR ++F LS ++ S+ L CP A+V+ N IK G L+ P+ + Q+ R + +EQ I +R +VE +W SF+ E TA ++ +E+LD + + S+ + L + L D H + ++ LLCEW+VS R G HR +VA++++ I + S Q L++FLDT++P++ D ++ F NLV LF ELI ++FS N YM +I+RG + P P + + + H S + SP + P+ +R GLN P + D RH+QY HFPIP + HE N R LY R RD + ++R+ +DI K+ ++ M + QIEK + RR + E+ AE I RF+ L+++D V +Q N L + A L + LP I + +L+E S N S LI + ++ L+ + + + L+ + SL+ SY +CI+ L + + L+ + ++F G+ + ++ + S RC A + + SC+ L+S F K++N ++ N++P S++ + + +D + V+C L + R+S V N L+HV D D++ I + E + LS+EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S RL IL LF Q N + +V D +LL++S ++ + +LK + V D L+ + T + S RR+ S + + VLR IC WV R + L D N L D +S++QA+ L+ +IC+P L T + NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE N + + + KP S+E + A+L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + L+H +K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ + I + ++KKLRKE+ D+ E +E ++ LLP K T DVI P ++ ++ + K+G V K++I+PW++ EGIK LS WF V D V +EE L++ H H +P +YY
Sbjct: 19 LGPPDVYPQDAKQKEDELTALNVKQGFN-NQPAVSADEHGSAKNVNFN------PAKISSNFSSIMSEKLRCNTLPDTGRRKPQVNQ--KDNFMLVTV-RTQSSINTWFSDLAGTKPLTHLA-KKVPIFGKKEEVFGFLARFSVPVMRAAWLIKMTCAYYAAITETKVKK-RHVMDPIIEWTQIITRYLWEQLQKIADYYRPALGGCSSPSGPMPPEVEVALKQWEYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRQGEDELLKLLLPLLLRYSNSLVQSAYLSRRLAY-FCTRRLAQLLEGSGSHPGHLMTAQTGTALPPAPAPPPPSGSAPSSPFSDLLQCPQHRPLVFGLSCMLQSIVLCCPSALVWHYSLTDNRIKT-GSPLDHLPIAPSSLPMPGGSSAFTQQ---VRRKLRDMEQQIKERGRSVEVRW---SFDKCQEATAGFPIGRVLHTLEVLDSHSFEKSDFSNNLDSLYNRIFGLGLGKDGHEISPDDDAVVTLLCEWAVSCKRYGHHRALVVAKLLEKRQAEIEAERCGDSEAVDEKGSVSSGSLSALSAPPVFQEVLLQFLDTQAPMLTDPANESERVEFYNLVLLFCELIRHDVFSHNMYMCTLISRGDLGIDPHAPRPRSPYEDPSDDTDRKEGEANSSIKLEDTTLSETMDIDHGSGALFEDMEKSEFPMFSPAMRCEGRSPGPEDGDRDIRRTVKGLNGEGPLSALYDQ---PRHIQYATHFPIPQEESCSHECNQRLVVLYGVGRQRDDARHIIKRITRDILKVLNRKSTSETGKVVVMGKVKQIEKQVNVPKLTLSPCGTDEGQRRRRAKPEAF---PTAEEIFCRFQQLSHFDQHQVTAQ---VSRNVLEQITSFALGL----SYHLPLVQHIQFIFDLMEYSLNISGLI----DFAIQLLNELSVVEAELLLKSSSLVGSYTMGLCLCIVAVLRHYHTCLILNQEQTAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPS---DSNMLWEQEFMLDTIINPSGHSVNCGMLGKLLSDSPTNRYSFVCNALVHVCAGDHDTDRVNDIAILCAELTGSCKALSSEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILVARQCLLLEDL---IRCAAIPSLLNAACSEQDSEA------GARLTCRILLHLFKTPQLNPCEPDGSKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELRGSGFSHPTGTDNASEEDIATRRAGGRPVSIETASLDEYAKYVLRSICQQEWVGERCVRS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLNDTEQGDNPQRQRIKHILQNLDQWTMRQSALELQLMIKQTPSNEMNSLLENIAKATIEVFQQSAENACAAPANSAALSNATSSNA--PPNSKTKPVLSSLERSGAWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYGQVQQIVSNWRE-DQYQDDCKTPQLLHDVLKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDR-QSESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGIKQSAPLSWGWFGTVRVDRRVSRMEEQQRLLLYHTHLKP--KPRSYY 1748
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Xenopus
Match: ENSXETT00000020329.1 (mediator complex subunit 12 [Source:NCBI gene;Acc:100495585]) HSP 1 Score: 472.241 bits (1214), Expect = 1.981e-135 Identity = 485/1801 (26.93%), Postives = 805/1801 (44.70%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKL----DLIRIKLM-----RNTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQCSDDE-QMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNS--VNLLLTNNKHPDRSIT----------------------DFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVY------NNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAA----GLIKVVELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS----------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXXXHRK--------SPEL--DRMSTG--DNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRG--------YMFDIIQIEKS--------------RKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSSSIDYVESVGMDLF---KINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCT-DVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN-----STANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGP-PFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLF----------SIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ +++ + N DT +RK V KD + + +++ I W L+ T P L K++P F KKE+V + ++ VP+ RA W IK++ + E+ KK R +D + +W R L E+L D R L + E E+ + ++EY +L + M+ + +LD E L W++ E+ E +++K LP LL + + +S L+R+L + C LL + HP +T +++ C HR ++F LS ++ S+ L CP A+V+ N IK G L+ P+ + Q+ R + +EQ I +R +VE +W SF+ E TA ++ +E+LD + + S+ + L + L D H + ++ LLCEW+VS R G HR +VA++++ I + S Q L++FLDT++P++ D ++ F NLV LF ELI ++FS N YM +I+RG + P P + + + H S + SP + + S G D +R GLN P + D RH+QY HFPIP + HE N R LY R RD + ++R+ +DI K+ ++ M + QIEK + RR + E+ AE I RF+ L+++D V +Q N L + A L + LP I + +L+E S N S LI + ++ L+ + + + L+ + SL+ SY +CI+ L + + L+ + ++F G+ + ++ + S RC A + + SC+ L+S F K++N ++ N++P S++ + + +D + V+C L + R+S V N L+HV D D++ I + E + LS+EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S RL IL LF Q N + +V D +LL++S ++ + +LK + V D L+ + T + S RR+ S + + VLR IC WV R + L D N L D +S++QA+ L+ +IC+P L T + NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE N + + + KP S+E + A+L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + L+H +K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ S+ + + ++KKLRKE+ D+ E +E ++ LLP K T DVI P ++ ++ + K+G V K++I+PW++ EGIK LS WF V D V +EE L++ H H +P +YY
Sbjct: 19 LGPPDVYPQDAKQKEDELTALNVKQGFN-NQPAVSADEHGSAKNVNFN------PAKISSNFSSIMSEKLRCNTLPDTGRRKPQVNQ--KDNFMLVTV-RTQSSINTWFSDLAGTKPLTHLA-KKVPIFGKKEEVFGFLARFSVPVMRAAWLIKMTCAYYAAITETKVKK-RHVMDPIIEWTQIITRYLWEQLQKIADYYRPALGGCSSPSGPMPPEVEVALKQWEYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRQGEDELLKLLLPLLLRYSNSLVQSAYLSRRLAY-FCTRRLAQLLEGSGSHPGHLMTAQTGTALPPAPAPPPPSGSAPSSPFSDLLQCPQHRPLVFGLSCMLQSIVLCCPSALVWHYSLTDNRIKT-GSPLDHLPIAPSSLPMPGGSSAFTQQV---RRKLRDMEQQIKERGRSVEVRW---SFDKCQEATAGFPIGRVLHTLEVLDSHSFEKSDFSNNLDSLYNRIFGLGLGKDGHEISPDDDAVVTLLCEWAVSCKRYGHHRALVVAKLLEKRQAEIEAERCGDSEAVDEKGSVSSGSLSALSAPPVFQEVLLQFLDTQAPMLTDPANESERVEFYNLVLLFCELIRHDVFSHNMYMCTLISRGDLGIDPHAPRPRSPYEDPSDDTDRKEGEANSSIKLEDTTLSETMDIDHGSGALFEDMEKSEFPMFSPAMRCEGRSPGPEDGDRDIRRTVKGLNGEGPLSALYDQ---PRHIQYATHFPIPQEESCSHECNQRLVVLYGVGRQRDDARHIIKRITRDILKVLNRKSTSETGKVVVMGKVKQIEKQVNVPKLTLSPCGTDEGQRRRRAKPEAF---PTAEEIFCRFQQLSHFDQHQVTAQ---VSRNVLEQITSFALGL----SYHLPLVQHIQFIFDLMEYSLNISGLI----DFAIQLLNELSVVEAELLLKSSSLVGSYTMGLCLCIVAVLRHYHTCLILNQEQTAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPS---DSNMLWEQEFMLDTIINPSGHSVNCGMLGKLLSDSPTNRYSFVCNALVHVCAGDHDTDRVNDIAILCAELTGSCKALSSEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILVARQCLLLEDL---IRCAAIPSLLNAACSEQDSEA------GARLTCRILLHLFKTPQLNPCEPDGSKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELRGSGFSHPTGTDNASEEDIATRRAGGRPVSIETASLDEYAKYVLRSICQQEWVGERCVRS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLNDTEQGDNPQRQRIKHILQNLDQWTMRQSALELQLMIKQTPSNEMNSLLENIAKATIEVFQQSAENACAAPANSAALSNATSSNA--PPNSKTKPVLSSLERSGAWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYGQVQQIVSNWRE-DQYQDDCKTPQLLHDVLKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDR-QSESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGIKQSAPLSWGWFGTVRVDRRVSRMEEQQRLLLYHTHLKP--KPRSYY 1748
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Mouse
Match: Med12l (mediator complex subunit 12-like [Source:MGI Symbol;Acc:MGI:2139916]) HSP 1 Score: 513.842 bits (1322), Expect = 3.537e-149 Identity = 489/1782 (27.44%), Postives = 825/1782 (46.30%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIR--IKLMRNTIDH------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQCSD-DEQMMKFYLPFLLYFGDRFKESEILTRKLLHG--------LCNSVNLLLTNNKH-------------------PDRSITDF-YAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYN------NIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVV---------SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRK---SPELDRMSTGDNPD-SVRSECSGLNQILPSIP--IVDYRNFN--RHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKL-ENVFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTII---VETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQ----NSTANSVSAFKKE-DVNLLSSSLQKVTTELLVDLLKMLAVHSD------------------KGRLQDQDYFD--LTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLI-DKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDT--MNRTFTNLNIWSLHFDQMKIQLLLTQIPEE-------ERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTE----SIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHT-----LFSIPNHGIK-----FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLT---TAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P +EH SA++I + P + + + +++ + N QDT K+K V KD + +S+ I+ W L+ P A ++ K++P KKEDV + KY VP+ RA W IK++ + + +E+ KK R D +W R L E+L I + +T D E E + ++EY +L M+ E +L+ E L W++ E+ D+ ++K LP +L + D F +S L+R+L + L +S NLL ++ H P S ++++ SC+ H +++ LS ++ +++L CP A+V+N I PG L+ + + Q+ R I ++EQ I QR AVE +W SF+ E TA I V E+LDR+ ++ S+ E L + + N ++ LLCEW+VS R+G HR VA++++ I + +S QN L+ FLDT++P + D + F NLV LF E I ++FS + YM +I+RG A+ L G S H S + SP NP S R +G + P ++ N++ RHLQY HFPIP+++ HE N R+ LY + RD + L+++ KDI K+ K+G + E +K+R+ +E + E++ ++ + L+Y+D V SQ + + S ++ LP I + +L+E + N + LI + ++ L+ + + + L+ + SL SY + +CI+ L ++ S L+ D ++F G+ + ++ V+ + RC A + + SC+ LRS F K+ + ++ N+ P D +D++E+ +M+ L N R+S V N L++V C RIN I E + ++LS+EW+ + +L N V FN +L + +DL F+++++T IA ++ARQCF D + V +L + P R+ +L LF Q T + D +LL+++ + + +LK + + D +G +D + D T N S+G +SI E + + + VLR IC WV +E P RL D LI D +SN QA+ LL +IC+P CT D + + R NL W+L +++QL++ Q ++ E ++++N++K I +F+ A+ N +N + S RQ + S E +L+ LI +LP + + +++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL +Q+ + N +E E+ DD + + ++H +++ RL LVG +FD +Q S + DW LLL ++I G V+MH+++ ELF TVLDM+ LI+ L S G + + ++KKL+KE+ DK + E ++ ++ LLP K T DVI P+ ++ ++ + +K +G V K++++PW++ EG KN LS WF V D V+ EE + ++ H H + +P +YY
Sbjct: 19 LGPPDVYPQDPKQKEDELTAVNVKQGFN-NQPAFTGDEHGSARNI----VINP--SKIGAYFSSILAEKLKLNTFQDTGKKKPQVNA--KDNYWL-VTARSQSAIHSWFSDLAGNKPLA-ILAKKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKK-RQAPDPNLEWTQISTRYLREQLVKISDFYHMASSTGDGPVPVPPEVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIRPVDDSLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSPNLLAAHSPHMIIGTNNTSIGTPSPGTPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKISNPGSPLDLLQVAPSSLPMPGGNTAFNQQV---RARIYEVEQQIKQRGRAVEVRW---SFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSASLAGSSLPVFQNVLLRFLDTQAPALSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTGLRSPAGENSDEHYSKDHDMKMEIFSPMPGESCENINPSLSRRLSVNGEKLLKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKGTTESGVGDEG--QKARKTKQE----VFPTPENVFTKLQLLSYFDQHQVTSQISNNVLEQI-------TSFASGTSYHLPLAHHIQLIFDLMEPALNINGLI----DFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLG-----KILNDNAANRYSFVCNTLMNV--CMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-------HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADA----EPGARMTCRLLLHLFRAPQACFFPQGTGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGSNNVNTMKNEDFGMRGLRRDGNAEDAWATSQNSKSYG----KSISIETANLR----EYARYVLRTICQQEWVGEHCLKE-PERLCTDKELILDPVLSNMQAQKLLQLICYPHGI---KECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPSSGSVAEMNNLLDNIAKATIEVFQQSADLNNNASNSGMSLFNPNTIGSVDPSSTRQNGIKTFLSSSERRGVWLVAPLIARLP-TSVQGRVLKAAGEELEKGQHLGS-SSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWRE-ERYQDDTKARQMMHEALQLRLNLVGGMFDTVQRSTQGTTDWALLLLQIITSGTVDMHTNN-ELFTTVLDMLGVLINGTLASDLSSASPGGSEENKRAYMNLVKKLKKELGDKRS-ESIDKVRQ-LLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQARGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRKVIKYEEQQHFLLYHTH--TMPKPRSYY 1727
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Mouse
Match: Med12l (mediator complex subunit 12-like [Source:MGI Symbol;Acc:MGI:2139916]) HSP 1 Score: 506.908 bits (1304), Expect = 1.003e-146 Identity = 490/1815 (27.00%), Postives = 823/1815 (45.34%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIR--IKLMRNTIDH------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQCSD-DEQMMKFYLPFLLYFGDRFKESEILTRKLLHG--------LCNSVNLLLTNNKH-------------------PDRSITDF-YAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYN------NIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVV---------SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGG-----FLSVAHNXXXXXHRKSPELDRMSTG----DNPDS--VRSECSGLNQILPSIPIVDYRNFN--------------------------------RHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKL-ENVFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTII---VETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQ----NSTANSVSAFKKE-DVNLLSSSLQKVTTELLVDLLKMLAVHSD------------------KGRLQDQDYFD--LTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLI-DKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDT--MNRTFTNLNIWSLHFDQMKIQLLLTQIPEE-------ERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTE----SIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHT-----LFSIPNHGIK-----FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P +EH SA++I + P + + + +++ + N QDT K+K V KD + +S+ I+ W L+ P A ++ K++P KKEDV + KY VP+ RA W IK++ + + +E+ KK R D +W R L E+L I + +T D E E + ++EY +L M+ E +L+ E L W++ E+ D+ ++K LP +L + D F +S L+R+L + L +S NLL ++ H P S ++++ SC+ H +++ LS ++ +++L CP A+V+N I PG L+ + + Q+ R I ++EQ I QR AVE +W SF+ E TA I V E+LDR+ ++ S+ E L + + N ++ LLCEW+VS R+G HR VA++++ I + +S QN L+ FLDT++P + D + F NLV LF E I ++FS + YM +I+RG A+ L G S H+ H L S D+ D +S+ + I +P N N RHLQY HFPIP+++ HE N R+ LY + RD + L+++ KDI K+ K+G + E +K+R+ +E + E++ ++ + L+Y+D V SQ + + S ++ LP I + +L+E + N + LI + ++ L+ + + + L+ + SL SY + +CI+ L ++ S L+ D ++F G+ + ++ V+ + RC A + + SC+ LRS F K+ + ++ N+ P D +D++E+ +M+ L N R+S V N L++V C RIN I E + ++LS+EW+ + +L N V FN +L + +DL F+++++T IA ++ARQCF D + V +L + P R+ +L LF Q T + D +LL+++ + + +LK + + D +G +D + D T N S+G +SI E + + + VLR IC WV +E P RL D LI D +SN QA+ LL +IC+P CT D + + R NL W+L +++QL++ Q ++ E ++++N++K I +F+ A+ N +N + S RQ + S E +L+ LI +LP + + +++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL +Q+ + N +E E+ DD + + ++H +++ RL LVG +FD +Q S + DW LLL ++I G V+MH+++ ELF TVLDM+ LI+ L S G + + ++KKL+KE+ DK + E ++ ++ LLP K T DVI P+ ++ ++ + KQG V K++++PW++ EG KN LS WF V D V+ EE + ++ H H + +P +YY
Sbjct: 19 LGPPDVYPQDPKQKEDELTAVNVKQGFN-NQPAFTGDEHGSARNI----VINP--SKIGAYFSSILAEKLKLNTFQDTGKKKPQVNA--KDNYWL-VTARSQSAIHSWFSDLAGNKPLA-ILAKKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKK-RQAPDPNLEWTQISTRYLREQLVKISDFYHMASSTGDGPVPVPPEVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIRPVDDSLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSPNLLAAHSPHMIIGTNNTSIGTPSPGTPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKISNPGSPLDLLQVAPSSLPMPGGNTAFNQQV---RARIYEVEQQIKQRGRAVEVRW---SFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSASLAGSSLPVFQNVLLRFLDTQAPALSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTGLRSPAGENSDEHYSKDHDMKMEEHSVMARLGLGSGATHIFDDVDKSDFKSDPASEFPIFSPMPGESCENINPSLSRRLSVNGEKLLKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKGTTESGVGDEG--QKARKTKQE----VFPTPENVFTKLQLLSYFDQHQVTSQISNNVLEQI-------TSFASGTSYHLPLAHHIQLIFDLMEPALNINGLI----DFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLG-----KILNDNAANRYSFVCNTLMNV--CMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-------HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADA----EPGARMTCRLLLHLFRAPQACFFPQGTGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGSNNVNTMKNEDFGMRGLRRDGNAEDAWATSQNSKSYG----KSISIETANLR----EYARYVLRTICQQEWVGEHCLKE-PERLCTDKELILDPVLSNMQAQKLLQLICYPHGI---KECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPSSGSVAEMNNLLDNIAKATIEVFQQSADLNNNASNSGMSLFNPNTIGSVDPSSTRQNGIKTFLSSSERRGVWLVAPLIARLP-TSVQGRVLKAAGEELEKGQHLGS-SSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWRE-ERYQDDTKARQMMHEALQLRLNLVGGMFDTVQRSTQGTTDWALLLLQIITSGTVDMHTNN-ELFTTVLDMLGVLINGTLASDLSSASPGGSEENKRAYMNLVKKLKKELGDKRS-ESIDKVRQ-LLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRKVIKYEEQQHFLLYHTH--TMPKPRSYY 1760
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Mouse
Match: Med12l (mediator complex subunit 12-like [Source:MGI Symbol;Acc:MGI:2139916]) HSP 1 Score: 504.982 bits (1299), Expect = 4.883e-146 Identity = 489/1817 (26.91%), Postives = 824/1817 (45.35%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIR--IKLMRNTIDH------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQCSD-DEQMMKFYLPFLLYFGDRFKESEILTRKLLHG--------LCNSVNLLLTNNKH-------------------PDRSITDF-YAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYN------NIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVV---------SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGG-----FLSVAHNXXXXXHRKSPELDRMSTG----DNPDS--VRSECSGLNQILPSIPIVDYRNFN--------------------------------RHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKL-ENVFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTII---VETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQ----NSTANSVSAFKKE-DVNLLSSSLQKVTTELLVDLLKMLAVHSD------------------KGRLQDQDYFD--LTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLI-DKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDT--MNRTFTNLNIWSLHFDQMKIQLLLTQIPEE-------ERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTE----SIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHT-----LFSIPNHGIK-----FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLT---TAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P +EH SA++I + P + + + +++ + N QDT K+K V KD + +S+ I+ W L+ P A ++ K++P KKEDV + KY VP+ RA W IK++ + + +E+ KK R D +W R L E+L I + +T D E E + ++EY +L M+ E +L+ E L W++ E+ D+ ++K LP +L + D F +S L+R+L + L +S NLL ++ H P S ++++ SC+ H +++ LS ++ +++L CP A+V+N I PG L+ + + Q+ R I ++EQ I QR AVE +W SF+ E TA I V E+LDR+ ++ S+ E L + + N ++ LLCEW+VS R+G HR VA++++ I + +S QN L+ FLDT++P + D + F NLV LF E I ++FS + YM +I+RG A+ L G S H+ H L S D+ D +S+ + I +P N N RHLQY HFPIP+++ HE N R+ LY + RD + L+++ KDI K+ K+G + E +K+R+ +E + E++ ++ + L+Y+D V SQ + + S ++ LP I + +L+E + N + LI + ++ L+ + + + L+ + SL SY + +CI+ L ++ S L+ D ++F G+ + ++ V+ + RC A + + SC+ LRS F K+ + ++ N+ P D +D++E+ +M+ L N R+S V N L++V C RIN I E + ++LS+EW+ + +L N V FN +L + +DL F+++++T IA ++ARQCF D + V +L + P R+ +L LF Q T + D +LL+++ + + +LK + + D +G +D + D T N S+G +SI E + + + VLR IC WV +E P RL D LI D +SN QA+ LL +IC+P CT D + + R NL W+L +++QL++ Q ++ E ++++N++K I +F+ A+ N +N + S RQ + S E +L+ LI +LP + + +++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL +Q+ + N +E E+ DD + + ++H +++ RL LVG +FD +Q S + DW LLL ++I G V+MH+++ ELF TVLDM+ LI+ L S G + + ++KKL+KE+ DK + E ++ ++ LLP K T DVI P+ ++ ++ + +K +G V K++++PW++ EG KN LS WF V D V+ EE + ++ H H + +P +YY
Sbjct: 19 LGPPDVYPQDPKQKEDELTAVNVKQGFN-NQPAFTGDEHGSARNI----VINP--SKIGAYFSSILAEKLKLNTFQDTGKKKPQVNA--KDNYWL-VTARSQSAIHSWFSDLAGNKPLA-ILAKKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKK-RQAPDPNLEWTQISTRYLREQLVKISDFYHMASSTGDGPVPVPPEVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIRPVDDSLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSPNLLAAHSPHMIIGTNNTSIGTPSPGTPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKISNPGSPLDLLQVAPSSLPMPGGNTAFNQQV---RARIYEVEQQIKQRGRAVEVRW---SFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSASLAGSSLPVFQNVLLRFLDTQAPALSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTGLRSPAGENSDEHYSKDHDMKMEEHSVMARLGLGSGATHIFDDVDKSDFKSDPASEFPIFSPMPGESCENINPSLSRRLSVNGEKLLKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKGTTESGVGDEG--QKARKTKQE----VFPTPENVFTKLQLLSYFDQHQVTSQISNNVLEQI-------TSFASGTSYHLPLAHHIQLIFDLMEPALNINGLI----DFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLG-----KILNDNAANRYSFVCNTLMNV--CMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-------HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADA----EPGARMTCRLLLHLFRAPQACFFPQGTGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGSNNVNTMKNEDFGMRGLRRDGNAEDAWATSQNSKSYG----KSISIETANLR----EYARYVLRTICQQEWVGEHCLKE-PERLCTDKELILDPVLSNMQAQKLLQLICYPHGI---KECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPSSGSVAEMNNLLDNIAKATIEVFQQSADLNNNASNSGMSLFNPNTIGSVDPSSTRQNGIKTFLSSSERRGVWLVAPLIARLP-TSVQGRVLKAAGEELEKGQHLGS-SSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWRE-ERYQDDTKARQMMHEALQLRLNLVGGMFDTVQRSTQGTTDWALLLLQIITSGTVDMHTNN-ELFTTVLDMLGVLINGTLASDLSSASPGGSEENKRAYMNLVKKLKKELGDKRS-ESIDKVRQ-LLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQARGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRKVIKYEEQQHFLLYHTH--TMPKPRSYY 1762
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Mouse
Match: Med12 (mediator complex subunit 12 [Source:MGI Symbol;Acc:MGI:1926212]) HSP 1 Score: 474.937 bits (1221), Expect = 3.300e-136 Identity = 485/1824 (26.59%), Postives = 809/1824 (44.35%), Query Frame = 2
Query: 44 SLETHPLKCLKQTEGYNSHKVLLGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMR-------------NTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTN-NKHPDRSIT----------------------DFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRKSPELDRMSTGDNPDSVRS--------------------------ECSGLNQILPSIPIVDYR-----------------NFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYM-------------FDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSS-----SIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHV-VQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN---STAN--SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRV-----LREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIK----------FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIK---NLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
S E PLK L+ LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ ++I + N DT +RK ++ + + A +S+ I W L+ T P L K++P F KKE+V + KY VP+ RA W IK++ + +E+ KK ++ D ++W + L E+L + + R + H+ EM + +++Y +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + + L L + H I +++ C HR ++F LS ++ ++ L CP A+V++ GSPLD LP A S LP P G R + ++EQ I +R AVE +W SF+ E TA I V E+LD + + S+ + LC + L D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ D + ++ F NLV LF ELI ++FS N Y +I+RG A P PP S + + RK E S ++P S C G P P V+ + RH+QY HFPIP + HE N R L+ + RD + ++++ KDI K+ ++G D+ + + RR R E+ AE I ++F+ L++YD V +Q + + ++ + LP + + +L+E YSL I + + ++ L+ + + + L+ + L+ SY + +CI+ L + + L+ D ++F G+ + ++ + S RC A + + SC+ L+S F K++N ++ N++P + ID +E+ F + S L N R+S V N L+HV V D D++ I + E LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S P RL IL LF Q N S N +V D +LL++S ++ + +LK + V D L+ + ++ S + ++ + +L V LR IC WV R + L D N L D +S++QA+ L+ +IC+P L + R NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE ++ + S + KP S+E + +L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q+ + N +E + + DD + K L+H ++K RL LVG +FD +Q S + +W LL ++II G V+M S++ ELF TVLDM+S LI+ + I + ++KKL+K++ ++ + +E + LLP K DVI P ++ ++ + K+G V K++I+PWE+ EG+K S +WF V D V EE L++ H H RP YY
Sbjct: 8 SYEHRPLKRLR-----------LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVNFN------PAKISSNFSSIIAEKLRCNTLSDTGRRK-SLMNQKDNFWLVTA--RSQSAINTWFTDLAGTKPLTHLA-KKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAMSETKVKK-KNTADPFTEWTQIITKYLWEQLQKM-AEYYRPGPAGSGGCGSTIGPLPHDVEMAIRQWDYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGE-FVQSAYLSRRLAYFCTRRLALQLDGVSSHSSHVIAAQSTSSLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRW---SFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSVASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPP-----SPFDDPTDDPERKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPAKEKIEGTLGILYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAF---PTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFAL-------GMSYHLPLVQHVQFIFDLME----YSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKS-----LSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---IRCAAIPSLLNAACSEQDS------EPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELKGSGFTVPGGTEELPEEEGGGGSSGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLLDNEDGENPQRQRIKRILKNLDQWTMRQSSLELQLMIKQTPNTEMNSLLENIAKATIEVFQQSAETGSSSGSTASNM----------PSSSKTKPVLSSLERSGVWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLASLHSQVHQIVINWRENQYL-DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAQLLLEIIISGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLQKDLGER-QSDSLEKVHQ-LLPLPKQNRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWELFEGLKPSTAPLSWAWFGTVRVDRRVARGEEQQRLLLYHTHLRP--RPRAYY 1740
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Mouse
Match: Med12 (mediator complex subunit 12 [Source:MGI Symbol;Acc:MGI:1926212]) HSP 1 Score: 474.937 bits (1221), Expect = 3.433e-136 Identity = 485/1824 (26.59%), Postives = 809/1824 (44.35%), Query Frame = 2
Query: 44 SLETHPLKCLKQTEGYNSHKVLLGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMR-------------NTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTN-NKHPDRSIT----------------------DFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRKSPELDRMSTGDNPDSVRS--------------------------ECSGLNQILPSIPIVDYR-----------------NFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYM-------------FDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSS-----SIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHV-VQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN---STAN--SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRV-----LREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIK----------FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIK---NLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
S E PLK L+ LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ ++I + N DT +RK ++ + + A +S+ I W L+ T P L K++P F KKE+V + KY VP+ RA W IK++ + +E+ KK ++ D ++W + L E+L + + R + H+ EM + +++Y +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + + L L + H I +++ C HR ++F LS ++ ++ L CP A+V++ GSPLD LP A S LP P G R + ++EQ I +R AVE +W SF+ E TA I V E+LD + + S+ + LC + L D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ D + ++ F NLV LF ELI ++FS N Y +I+RG A P PP S + + RK E S ++P S C G P P V+ + RH+QY HFPIP + HE N R L+ + RD + ++++ KDI K+ ++G D+ + + RR R E+ AE I ++F+ L++YD V +Q + + ++ + LP + + +L+E YSL I + + ++ L+ + + + L+ + L+ SY + +CI+ L + + L+ D ++F G+ + ++ + S RC A + + SC+ L+S F K++N ++ N++P + ID +E+ F + S L N R+S V N L+HV V D D++ I + E LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S P RL IL LF Q N S N +V D +LL++S ++ + +LK + V D L+ + ++ S + ++ + +L V LR IC WV R + L D N L D +S++QA+ L+ +IC+P L + R NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE ++ + S + KP S+E + +L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q+ + N +E + + DD + K L+H ++K RL LVG +FD +Q S + +W LL ++II G V+M S++ ELF TVLDM+S LI+ + I + ++KKL+K++ ++ + +E + LLP K DVI P ++ ++ + K+G V K++I+PWE+ EG+K S +WF V D V EE L++ H H RP YY
Sbjct: 8 SYEHRPLKRLR-----------LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVNFN------PAKISSNFSSIIAEKLRCNTLSDTGRRK-SLMNQKDNFWLVTA--RSQSAINTWFTDLAGTKPLTHLA-KKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAMSETKVKK-KNTADPFTEWTQIITKYLWEQLQKM-AEYYRPGPAGSGGCGSTIGPLPHDVEMAIRQWDYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGE-FVQSAYLSRRLAYFCTRRLALQLDGVSSHSSHVIAAQSTSSLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRW---SFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSVASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPP-----SPFDDPTDDPERKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPAKEKIEGTLGILYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAF---PTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFAL-------GMSYHLPLVQHVQFIFDLME----YSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKS-----LSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---IRCAAIPSLLNAACSEQDS------EPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELKGSGFTVPGGTEELPEEEGGGGSSGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLLDNEDGENPQRQRIKRILKNLDQWTMRQSSLELQLMIKQTPNTEMNSLLENIAKATIEVFQQSAETGSSSGSTASNM----------PSSSKTKPVLSSLERSGVWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLASLHSQVHQIVINWRENQYL-DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAQLLLEIIISGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLQKDLGER-QSDSLEKVHQ-LLPLPKQNRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWELFEGLKPSTAPLSWAWFGTVRVDRRVARGEEQQRLLLYHTHLRP--RPRAYY 1740
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. UniProt/SwissProt
Match: sp|Q8BQM9|MD12L_MOUSE (Mediator of RNA polymerase II transcription subunit 12-like protein OS=Mus musculus OX=10090 GN=Med12l PE=1 SV=2) HSP 1 Score: 513.842 bits (1322), Expect = 2.474e-148 Identity = 489/1782 (27.44%), Postives = 825/1782 (46.30%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIR--IKLMRNTIDH------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQCSD-DEQMMKFYLPFLLYFGDRFKESEILTRKLLHG--------LCNSVNLLLTNNKH-------------------PDRSITDF-YAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYN------NIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVV---------SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRK---SPELDRMSTGDNPD-SVRSECSGLNQILPSIP--IVDYRNFN--RHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKL-ENVFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTII---VETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQ----NSTANSVSAFKKE-DVNLLSSSLQKVTTELLVDLLKMLAVHSD------------------KGRLQDQDYFD--LTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLI-DKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDT--MNRTFTNLNIWSLHFDQMKIQLLLTQIPEE-------ERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTE----SIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHT-----LFSIPNHGIK-----FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLT---TAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P +EH SA++I + P + + + +++ + N QDT K+K V KD + +S+ I+ W L+ P A ++ K++P KKEDV + KY VP+ RA W IK++ + + +E+ KK R D +W R L E+L I + +T D E E + ++EY +L M+ E +L+ E L W++ E+ D+ ++K LP +L + D F +S L+R+L + L +S NLL ++ H P S ++++ SC+ H +++ LS ++ +++L CP A+V+N I PG L+ + + Q+ R I ++EQ I QR AVE +W SF+ E TA I V E+LDR+ ++ S+ E L + + N ++ LLCEW+VS R+G HR VA++++ I + +S QN L+ FLDT++P + D + F NLV LF E I ++FS + YM +I+RG A+ L G S H S + SP NP S R +G + P ++ N++ RHLQY HFPIP+++ HE N R+ LY + RD + L+++ KDI K+ K+G + E +K+R+ +E + E++ ++ + L+Y+D V SQ + + S ++ LP I + +L+E + N + LI + ++ L+ + + + L+ + SL SY + +CI+ L ++ S L+ D ++F G+ + ++ V+ + RC A + + SC+ LRS F K+ + ++ N+ P D +D++E+ +M+ L N R+S V N L++V C RIN I E + ++LS+EW+ + +L N V FN +L + +DL F+++++T IA ++ARQCF D + V +L + P R+ +L LF Q T + D +LL+++ + + +LK + + D +G +D + D T N S+G +SI E + + + VLR IC WV +E P RL D LI D +SN QA+ LL +IC+P CT D + + R NL W+L +++QL++ Q ++ E ++++N++K I +F+ A+ N +N + S RQ + S E +L+ LI +LP + + +++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL +Q+ + N +E E+ DD + + ++H +++ RL LVG +FD +Q S + DW LLL ++I G V+MH+++ ELF TVLDM+ LI+ L S G + + ++KKL+KE+ DK + E ++ ++ LLP K T DVI P+ ++ ++ + +K +G V K++++PW++ EG KN LS WF V D V+ EE + ++ H H + +P +YY
Sbjct: 19 LGPPDVYPQDPKQKEDELTAVNVKQGFN-NQPAFTGDEHGSARNI----VINP--SKIGAYFSSILAEKLKLNTFQDTGKKKPQVNA--KDNYWL-VTARSQSAIHSWFSDLAGNKPLA-ILAKKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKK-RQAPDPNLEWTQISTRYLREQLVKISDFYHMASSTGDGPVPVPPEVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIRPVDDSLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSPNLLAAHSPHMIIGTNNTSIGTPSPGTPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKISNPGSPLDLLQVAPSSLPMPGGNTAFNQQV---RARIYEVEQQIKQRGRAVEVRW---SFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSASLAGSSLPVFQNVLLRFLDTQAPALSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTGLRSPAGENSDEHYSKDHDMKMEIFSPMPGESCENINPSLSRRLSVNGEKLLKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKGTTESGVGDEG--QKARKTKQE----VFPTPENVFTKLQLLSYFDQHQVTSQISNNVLEQI-------TSFASGTSYHLPLAHHIQLIFDLMEPALNINGLI----DFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLG-----KILNDNAANRYSFVCNTLMNV--CMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-------HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADA----EPGARMTCRLLLHLFRAPQACFFPQGTGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGSNNVNTMKNEDFGMRGLRRDGNAEDAWATSQNSKSYG----KSISIETANLR----EYARYVLRTICQQEWVGEHCLKE-PERLCTDKELILDPVLSNMQAQKLLQLICYPHGI---KECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPSSGSVAEMNNLLDNIAKATIEVFQQSADLNNNASNSGMSLFNPNTIGSVDPSSTRQNGIKTFLSSSERRGVWLVAPLIARLP-TSVQGRVLKAAGEELEKGQHLGS-SSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWRE-ERYQDDTKARQMMHEALQLRLNLVGGMFDTVQRSTQGTTDWALLLLQIITSGTVDMHTNN-ELFTTVLDMLGVLINGTLASDLSSASPGGSEENKRAYMNLVKKLKKELGDKRS-ESIDKVRQ-LLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQARGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRKVIKYEEQQHFLLYHTH--TMPKPRSYY 1727
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. UniProt/SwissProt
Match: sp|Q86YW9|MD12L_HUMAN (Mediator of RNA polymerase II transcription subunit 12-like protein OS=Homo sapiens OX=9606 GN=MED12L PE=1 SV=2) HSP 1 Score: 504.212 bits (1297), Expect = 4.429e-145 Identity = 487/1780 (27.36%), Postives = 830/1780 (46.63%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIR--IKLMRNTIDH------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC-SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHG--------LCNSVNLLLTNNKH----PDRS----------------ITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLN---RDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVV---------SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARG-LFESVANLPLPPIGGFLSVAHNXXXXXHRKSPELDRMSTGDNPDSVRSE--------CSGLNQILPSIPIVDYRNFN--RHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKL-ENVFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTII---VETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQ----NSTANSVSAFKKE-DVNLLSSSLQKVTTELLVDLLKMLAVHSD------------------KGRLQDQDYFDL--TENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLI-DKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDT--MNRTFTNLNIWSLHFDQMKIQLLLTQIPEE-------ERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTE----SIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIH-TLFSIPNHGI---------KFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P +EH SA++I + P + + + +++ + N QDT K+K V KD + +S+ I+ W L+ P + ++ K++P KKEDV + KY VP+ RA W IK++ + + +E+ KK R D +W R L E+L I + +T D E E + ++EY +L M+ E +L+ E L W++ E+ D+ ++K LP +L + D F +S L+R+L + L +S NLL ++ H P+ S + ++++ SC+ H +++ LS ++ +++L CP A+V+N + N L + PG N R I ++EQ I QR AVE +W SF+ E TA I V E+LDR+ ++ S+ E L + + N ++ LLCEW+VS R+G HR VA++++ I + +S QN L+ FLDT++P + D + F NLV LF E I ++FS + YM +I+RG L + + P P+G A S H E+ G++ ++ + C L + ++ N++ RHLQY HFPIP+++ HE N R+ LY + RD + L+++ KDI K+ K+ + E +K+R++ +E + E++ ++ + L+Y+D V SQ + + S ++ LP I + +L+E + N + LI + ++ L+ + + + L+ + SL SY + +CI+ L ++ S L+ D ++F G+ + ++ V S RC A + + SC+ LRS F K+ + ++ N+ P D +D++E+ +M+ L N R+S V N L++V C RIN I E + ++LS+EW+ + +L N V FN +L + +DL F+++++T IA ++ARQCF D + V +L + P R+ +L LF Q +T + D +LL+++ + + +LK + + D +G D + D+ N S G +SI E + + + VLR IC WV +E P RL D LI D +SN QA+ LL +IC+P CT D + + R NL W+L +++QL++ Q ++ E ++++N++K I +F+ A+ N +N + + S RQ + S E +L+ LI +LP + + +++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL +Q+ + N +E E+ DD++ + ++H +++ RL LVG +FD +Q S + DW LLL ++I G V+MH+++ ELF TVLDM+ LI+ TL S ++ + ++KKL+KE+ DK + E ++ ++ LLP K T DVI P+ ++ ++ + KQG V K++++PW++ EG KN LS WF V D V+ EE +L++ H HP + +P +YY
Sbjct: 19 LGPPDVYPQDPKQKEDELTAVNVKQGFN-NQPAFTGDEHGSARNI----VINP--SKIGAYFSSILAEKLKLNTFQDTGKKKPQVNA--KDNYWL-VTARSQSAIHSWFSDLAGNKPLS-ILAKKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKK-RQAPDPNLEWTQISTRYLREQLAKISDFYHMASSTGDGPVPVPPEVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIRPMDDDLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSPNLLAAHSPHMMIGPNNSSIGAPSPGPPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKSANPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRW---SFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWANQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSSSLAGSSLPVFQNVLLRFLDTQAPSLSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTRPRSPVG---ENADEHYSKDHDVKMEIFSPMPGESCENANTSLGRRMSVNCEKLVKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTETGVGDEG--QKARKNKQETFPTL----ETVFTKLQLLSYFDQHQVTSQISNNVLEQI-------TSFASGTSYHLPLAHHIQLIFDLMEPALNINGLI----DFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLG-----KILSDNAANRYSFVCNTLMNV--CMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-------HVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADA----EPGARMTCRLLLHLFRAPQACFLPQATGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNSVSSLKNDDFTMRGLRCDGNADDIWTASQNPKSCG----KSISIETANLR----EYARYVLRTICQQEWVGEHCLKE-PERLCTDKELILDPVLSNMQAQKLLQLICYPHGI---KECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSADLN-NSSNSGMSLFNPNSIGSADTSSTRQNGIKTFLSSSERRGVWLVAPLIARLP-TSVQGRVLKAAGEELEKGQHLGS-SSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWRE-ERYQDDIKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMHTNN-ELFTTVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKRS-ESIDKVRQ-LLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRRVIKYEEQHHLLLYHTHP--MPKPRSYY 1724
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. UniProt/SwissProt
Match: sp|Q2QCI8|MED12_DANRE (Mediator of RNA polymerase II transcription subunit 12 OS=Danio rerio OX=7955 GN=med12 PE=2 SV=1) HSP 1 Score: 503.056 bits (1294), Expect = 1.274e-144 Identity = 514/1821 (28.23%), Postives = 834/1821 (45.80%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVS-AMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDH-----------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTNNK---------------------------------HPDRSITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPIIDSQISADSE--PFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXX-----------XHRKSPELDRMSTGDNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIV---ETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNSTANSVSAFKKE--------DVNLLSSSLQKVTTELLVDLLKMLAVHSD-----KGRLQDQDYFDLTENNQVSFGPPFRR-SIDTEESFIHMKIWNFTLRVLREICCVSWV--RIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLF----------SIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPD--NYYTSFPEILPEDIKDPSISDPME 5029
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F ++ ++I + N DT KRK V KD + +S+ I +W L+ T P +L K++P F KKE+V + KY VP+ R+ W IK++ A HA I NK K R +D +W + L E+L + + R + E E + ++EY +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + +NLLL++ P TDFY C HR V+F LS ++ S+ L CP A+V++ N GSPLDLLP A S LP P G N R + ++E+ I +R AVE +W SF+ E TA I V E+LD + + S+ + L + D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ ++ +SE F NLV LF ELI ++FS N YM +I+RG S ++LP P + + + HNSS++ + SP ++ + S + G++ P+ P+V Y RH+QY HFPIP + HE N R LY + RD + ++++ KDI K+ ++ + + RK+S+ + AE I S+F+ L+++D V SQ + + ++ + LP I + +L+E S N S LI + LN + L+E + L+ + +L SY + +CI+ L ++ S L+ D ++F G+ ++ ++ V+ RC A + + SC+ L+S F K++N ++ NI P D+ ID + + +M+ N EL + R+S V N L+ V C D R+N I + E + LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D V CVA+ A +Q S P RL IL LF Q+N + K D +LL++S + + +LK + + D G D+ E++ S R SI+T ++ K VL+ IC WV R S S ++D VL+ N QA+ LL +IC+P L + + R N++ W++ +++QL++ Q E ++EN++K I +F+ AE ++ + +S S + S E + +L+ LI KLP + + ++ AA E+LE G+H + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + K ++H ++K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ S+ + + ++KKLRKE+ D+ + E +E ++ LLP K T DVI P ++ ++ EK G Q V K++I+PW+V EG+K+ LS WF + D V EE L++ H H I+P +YY + P LP++ ++P P E
Sbjct: 19 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVNFNSSKI------SSNFSSIIAEKLRCNTFPDTGKRKPQVNQ--KDNFWL-VTARSQSSINNWFTDLAGTKPLTQLA-KKVPIFSKKEEVFGYLAKYSVPVMRSAWMIKMTCAYHAAI--TENKMKKRHVIDPCIEWTPIITKYLWEQLQKV-AEFYRQSPSQGCGSPLPAPPAEVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLRLLLPLLLQYSGE-FVQSAYLSRRLAYFCTRRLNLLLSDGSIGPGPGGHQAHGISAQQGNALPPTPTSQPAGGNQPQTPFTDFYI----CPQHRPVVFGLSCMLQSIVLCCPSALVWHYSLTDSRNKTGSPLDLLPIAPSNLPMPGGNSTFNQQVRAKVREIEEQIKERGQAVEFRW---SFDKCQETTAGFTISRVLHTLEVLDNHSFEKSDFSNSLDSLYNRIFGSGQSKDGHEMSPDDDAVVTLLCEWAVSCKRSGPHRAMVVAKLLEKRQTEIEAERCGESEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPVL-TEPGNESERVEFSNLVLLFYELIRHDVFSHNIYMCTLISRGDLASNSHLPRPRSPSDEPSDESERKDQDAGSSVKMEDTGMSESMEIDHNSSANFDEMFSPPMHCESKGSPSPEKQAQEQESKSTAKD-KGMD---PAFPLV-YEQ-PRHIQYATHFPIPQEESASHECNQRLVVLYGVGKQRDEARHAIKKITKDILKVLNRKSTAETGGEEGQKRKRSKPE-------AFPTAEDIFSKFQHLSHFDQHQVTSQVSRNVLEQITSFAL-------GMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQL-LNELSLVE---AELLLKSSNLAGSYTTGLCLCIVAVLRRYHSCLILNPDQTAQVFDGLRIVVKSGVNPADCSSAERCILAYLYDLYTSCSHLKSKFGEIFSEFCSKVKNSIYYNIDPSDSNMLWDQMFMIDAITNPTAHNLNHSMLGKITN--ELNDSPANRYSFVCNVLMDV--CVDHRDPERVNDIGILCAELTAYCRSLSAEWLGVLKALCCSSNNG------NCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---VRCVAIPSLLNAACSEQDS------EPGARLTCRILLHLFRTPQRNPCPQDGTKSDKSIVGIRSSCDRHLLAASQNSIVVGAVFAVLKAVFMLGDAELKGSGFSHPAGLDDIGEDDMGSKKSGGRNVSIETASLVVYAKY------VLKSICHQEWVGERCLKSLSEDSSALQDPVLV-----NIQAQRLLQLICYPHRQL-DSEEGDNPQRQRIKRILQNMDQWTMRQSSLELQLMIKQSSNNELYSLLENIAKATIEVFQKSAEMNSSNPSWNGSAVSGSSVSNSNSASKLKPVLSSSERSGVWLVAPLIGKLP-TSVQGHVLKAAGEELEKGQHLGP-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWRE-DQYQDDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQS-ESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFEKEGLQ---VSTKQKISPWDVFEGLKHSAPLSWGWFGTIRVDRKVTKFEEQQRLLLYHTH----IKPKQRSYYLA-PLNLPQEEEEPLTPVPPE 1747
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. UniProt/SwissProt
Match: sp|A2AGH6|MED12_MOUSE (Mediator of RNA polymerase II transcription subunit 12 OS=Mus musculus OX=10090 GN=Med12 PE=1 SV=1) HSP 1 Score: 474.937 bits (1221), Expect = 2.401e-135 Identity = 485/1824 (26.59%), Postives = 809/1824 (44.35%), Query Frame = 2
Query: 44 SLETHPLKCLKQTEGYNSHKVLLGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMR-------------NTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTN-NKHPDRSIT----------------------DFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRKSPELDRMSTGDNPDSVRS--------------------------ECSGLNQILPSIPIVDYR-----------------NFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYM-------------FDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSS-----SIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHV-VQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN---STAN--SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRV-----LREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIK----------FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIK---NLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
S E PLK L+ LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ ++I + N DT +RK ++ + + A +S+ I W L+ T P L K++P F KKE+V + KY VP+ RA W IK++ + +E+ KK ++ D ++W + L E+L + + R + H+ EM + +++Y +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + + L L + H I +++ C HR ++F LS ++ ++ L CP A+V++ GSPLD LP A S LP P G R + ++EQ I +R AVE +W SF+ E TA I V E+LD + + S+ + LC + L D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ D + ++ F NLV LF ELI ++FS N Y +I+RG A P PP S + + RK E S ++P S C G P P V+ + RH+QY HFPIP + HE N R L+ + RD + ++++ KDI K+ ++G D+ + + RR R E+ AE I ++F+ L++YD V +Q + + ++ + LP + + +L+E YSL I + + ++ L+ + + + L+ + L+ SY + +CI+ L + + L+ D ++F G+ + ++ + S RC A + + SC+ L+S F K++N ++ N++P + ID +E+ F + S L N R+S V N L+HV V D D++ I + E LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S P RL IL LF Q N S N +V D +LL++S ++ + +LK + V D L+ + ++ S + ++ + +L V LR IC WV R + L D N L D +S++QA+ L+ +IC+P L + R NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE ++ + S + KP S+E + +L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q+ + N +E + + DD + K L+H ++K RL LVG +FD +Q S + +W LL ++II G V+M S++ ELF TVLDM+S LI+ + I + ++KKL+K++ ++ + +E + LLP K DVI P ++ ++ + K+G V K++I+PWE+ EG+K S +WF V D V EE L++ H H RP YY
Sbjct: 8 SYEHRPLKRLR-----------LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVNFN------PAKISSNFSSIIAEKLRCNTLSDTGRRK-SLMNQKDNFWLVTA--RSQSAINTWFTDLAGTKPLTHLA-KKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAMSETKVKK-KNTADPFTEWTQIITKYLWEQLQKM-AEYYRPGPAGSGGCGSTIGPLPHDVEMAIRQWDYNEKLALFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGE-FVQSAYLSRRLAYFCTRRLALQLDGVSSHSSHVIAAQSTSSLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRW---SFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSVASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPP-----SPFDDPTDDPERKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPAKEKIEGTLGILYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAF---PTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFAL-------GMSYHLPLVQHVQFIFDLME----YSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKSKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKS-----LSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---IRCAAIPSLLNAACSEQDS------EPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELKGSGFTVPGGTEELPEEEGGGGSSGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLLDNEDGENPQRQRIKRILKNLDQWTMRQSSLELQLMIKQTPNTEMNSLLENIAKATIEVFQQSAETGSSSGSTASNM----------PSSSKTKPVLSSLERSGVWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLASLHSQVHQIVINWRENQYL-DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAQLLLEIIISGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLQKDLGER-QSDSLEKVHQ-LLPLPKQNRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWELFEGLKPSTAPLSWAWFGTVRVDRRVARGEEQQRLLLYHTHLRP--RPRAYY 1740
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. UniProt/SwissProt
Match: sp|Q5RCU2|MED12_PONPY (Mediator of RNA polymerase II transcription subunit 12 OS=Pongo pygmaeus OX=9600 GN=MED12 PE=2 SV=2) HSP 1 Score: 472.626 bits (1215), Expect = 1.231e-134 Identity = 481/1797 (26.77%), Postives = 802/1797 (44.63%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMR-------------NTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTNNKHPDRSITD-----------------------FYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPII-DSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRKS-------PELDRMSTGDNPDSVRSE---------------CSGLNQILPSIPIVDYR-----------------NFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYM-------------FDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFV--SVNGYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDKDRSS-----SIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHV-VQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN---STAN--SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLR-----VLREICCVSWVRIRFSQETPSRLIRD-NVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIK----------FFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ ++I + N DT +RK V KD + +S+ I W L+ T P +L K++P F KKE+V + KY VP+ RA W IK++ + +E+ KK +VD +W + L E+L + + R + H+ E+ + +++Y +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + + L L + +++ C HR ++F LS ++ ++ L CP A+V++ GSPLD LP A S LP P G R + ++EQ I +R AVE +W SF+ E TA I V E+LD + + S+ + LC + L D H + ++ LLCEW+VS R+G HR +VA++++ I + +S Q+ L++FLDT++P++ D + ++ F NLV LF ELI ++FS N Y +I+RG A P PP F A + S P L D SV E C G P P V+ + RH+QY HFPIP + HE N R L+ + RD + ++++ KDI K+ ++G D+ + + RR R E+ AE I ++F+ L++YD V +Q + + ++ + LP + + +L+E YSL I + + ++ L+ + + + L+ + L+ SY + +CI+ L + + L+ D ++F G+ + ++ + S RC A + + SC+ L++ F K++N ++ N++P + ID +E+ F + S L N R+S V N L+HV V D D++ I + E LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D + C A+ A +Q S P RL IL LF Q N S N +V D +LL++S ++ + +LK + V D L+ + ++ S + ++ + +L VLR IC WV R + L D N L D +S++QA+ L+ +IC+P L + R NL+ W++ +++QL++ Q P E ++EN++K I +F+ AE ++ + S + KP S+E + +L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q+ ++N ++ + + DD + K L+H ++K RL LVG +FD +Q S + +W +LL ++II G V+M S++ ELF TVLDM+S LI+ + I + + KKL+KE+ ++ + + +E ++ LLP K T DVI P ++ ++ + K+G V K++I+PW++ EG+K LS WF V D V EE L++ H H RP YY
Sbjct: 19 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVSFN------PAKISSNFSSIIAEKLRCNTLPDTGRRKPQVNQ--KDNFWL-VTARSQSAINTWFTDLAGTKPLTQLA-KKVPIFSKKEEVFGYLAKYTVPVMRAAWLIKMTCAYYAAISETKVKK--RHVDPFMEWTQIITKYLWEQLQKM-AEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLRYSGE-FVQSAYLSRRLAYFCTRRLALQLDGVSSHSSHVISAQSTSTLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILLCCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIKERGQAVEVRW---SFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGLGPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEAADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCELIRHDVFSHNMYTCTLISRGDLAFGAPGPRPP-SPFDDPADDPEHKEAEGSSSSKLEDPGLSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIEGTLGVLYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKDILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAF---PTAEDIFAKFQHLSHYDQHQVTAQVSRNVLEQITSFAL-------GMSYHLPLVQHVQFIFDLME----YSLSISGLIDFAIQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGLCGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVEPSESNMRWAPEFMIDTLENPAAHTFTYTGLGKS-----LSENPANRYSFVCNALMHVCVGHHDPDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNG------TCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---IRCAAIPSLLNAACSEQDS------EPGARLTCRILLHLFKTPQLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGD-AELKGSGFTVTGGTEELPEEEGGGGSGGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKS----LCEDSNDLQDPVLSSAQAQRLMQLICYPH-RLLDNEDGENPQRQRIKRILQNLDQWTMRQSSLELQLMIKQTPNNEMNSLLENIAKATIEVFQQSAETGSSSGSTASNM----------PSSSKTKPVLSSLERSGVWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVHQIVNNWRDDQYL-DDCKPKQLMHEALKLRLNLVGGMFDTVQRSTQQTTEWAMLLLEIIISGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKLQKELGERQS-DSLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKPSAPLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRP--RPRAYY 1738
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. TrEMBL
Match: G7Y604 (Mediator of RNA polymerase II transcription subunit 12-like protein OS=Clonorchis sinensis OX=79923 GN=CLF_101547 PE=4 SV=1) HSP 1 Score: 753.821 bits (1945), Expect = 0.000e+0 Identity = 628/1976 (31.78%), Postives = 941/1976 (47.62%), Query Frame = 2
Query: 29 MSYYHSLETHPLKCLKQTEGYNSHKVLLGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVVEEHESAKDIGFEFISKPFLT---DLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNE----QCSDDEQM------------------------------MKFYLPFLLYFGDRFKESEILTRKLLHGLCNSV-NLLLTNNK----------HPDRS----ITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNL--NGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVVELLDRYDYNCYKDSSVFEGLCTVVV---SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDNI-HQNQSH----QSIQNCLVEFLDTKS----PIIDSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPI-----------------GGFLSVAHNXX------------XXXHRKSPELDRMSTGDNPDSVRSE---------CSGLNQILP----SIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEK-SRKKSRRDPREESM--------------------------------LIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSL-------------------------------NIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRSCPTFVMNMK--KLENVFRNIKPDK-----DRSSSIDYVESVGMD---LFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVSNDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNST--AN----------------------------SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYF------DLTENNQVSFGPPFRRSIDTEESF--------IHMKIWNF----------TLR----------VLREICCVSWVRIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQ--QANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCLAKDDNRSEFLKSLADQIEYYIDNAKETE-KMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIKFFQ-MIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQ-------------YRLTTAEKSG---------------------------------KQGCAVQRKERINPWEVIEGIKNLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYYTS--FPEILPEDIKDPSISDPMEIINSSGPPS 5056
MS + SLE LK K+++ PPDVY Q +QKEDL++E VR+G+ Y KPV +E++S + FLT L F V+ K ++ + QD K+ A+ ++ +P ++K++ W +LS + P +++ +R+PY K+++L E+ ++VPI+RA+W I + +H Q E+ K+K R V S+W + + L L ++L + E +++YL L++A+YD D+ DH EVL WL E Q S+DE +KF+L +LL FG RF E+E++ R+LL C + +++L+ ++ HP+ + + + Y E SC HR+V+ LS +I L L CP A V+N+I +L GSPLD++P + +ALP P G E R + +E I+ RS E W ++F + LIKV+++LDR DY+ K+ + E L + ++ + ++L+ LCEW+VS R G +R +VA +++ + H QS Q +Q L++FLDT + P Q D+EP RNLVCLF ELI+RE+F + Y+ MIARG+F +V PL G F +V++ + S + S + DR S DNPDSVRSE C G P S P+ + H YL HFP+P ++ Y HE N R Q LY + R RD + +R+L +DI K++T++ Y+ D++ E RKKS+ RE S LI+KL E I SRF CL+Y+DMECV+SQC PT L N +LAN L + S +++P P I LIE S N + LI I + L L E SR +T YMS + IG L + Q VL TMSD R+F + R G RC A + F S A ++S + N K+ +FR+++P + D+ + D +++ G D LF+ +L+ N N RFS V ++ V Q T ++++ + + E S+ L+ EW+ A+Y+++ P GY V S + D+ Y+++S+LI T+L R+C SDFL RVIC A+AQG+ Q V P + P+ RLA +IL RLFT E ST AN S F+ + LL+ +LQKVT ELLVD+LKML VH+DK +DQ D TE + G D E S IH + F LR VLREIC V WVR RF + R R+NVLID+ S +QAR LL++I HP D W + + + +M + ++L++W+L +K QLL TQI ++KDV+++V + I+ F+ QA +AN + D + P +L+P+LI KLP K Q++ A E L+ KHF HKN +DKE +L K S++L +P F LL VC+A+ D + L +Q+ Y+++NA +TE ++PD+LR + ++ ++ RL LVG F +Q+ EL DW LLL+KLI +GV+E S+ + LFY V DM+ +L+HT+ + K +Q + KK+R+E+ + +Y G+E I+ LLP K VIVT H +Q+ + A KSG K+G + KER+ PW++ + K LS A S + EE AN +I HDH +L RP +Y + +PE ++D SD E PPS
Sbjct: 1 MSAFPSLENRSLK--KKSDC---------PPDVYNQRDEQKEDLMSEDFVRDGYKYIKPVRDEYDSCRK------ESKFLTVNDSLWKFYHDVLAKKYDCSTYQDLKKKS---ASNVRET-IVPVVDKNQ--ANAWFRELSGSTPL-QILGRRVPYSKDKQEILSELVAHKVPISRAVWLINLILLHTPAQPENAKRKQRPTVHP-SEWTSNICQMLERNL----VQLCSES--GEQPSVEEDWDYLFTLLLALYDSDVADHWEVLLWLTKRAEGLWKQPSEDEAAPTQQQYSNYDNNGDEPLPTETIEETNMLNNVKFFLFYLLKFGRRFTENELIARRLLFWCCGTFRSIVLSESRVPAADNQAGNHPNNTEMQLVLEEYLETCSCPLHRSVVLSLSSMITCLILSCPSAAVWNSIPTGTDHLYLEGSPLDVIPYSTAALPMPQGPETTEIRQCLFDVENVIITRSQLAEVGWNRQAFTDVSGEEMERLIKVLDILDRQDYHSVKEHNPMEALFNRIFNDDAINVDTAILVTTLCEWAVSVHRVGIYRSVIVACLLEQLTHSFQSDPNPFQMLQQTLLDFLDTFTSNLPPYSTDQAPVDNEPMRNLVCLFAELIDREVFDHDIYVRRMIARGVF-AVECHPLATSTVTESHTATLTLSTSTHGKFQAVSNTTLLSNLPNNVTTQCSVASEMSEDNDRCSV-DNPDSVRSEAGFPSVTTSCCGYVTSAPHHPASEPLTGPARCSPHFHYLTHFPLPQDESYSHEENQRYQLLYGSLRARDRARSRIRQLVRDIVKIFTRKFYLIDVVHGEMCKRKKSKDREREVSTAPVANMPSSSGHRVVAVTTTGGGSGGASDDAHLIDKLHEDIMSRFICLSYHDMECVISQCTPTFTKVLSGCNGQGNPTVIGDDYHSGSTLGMANPPSPPNNAGVLAN-LTNQSPIYMPVPNSIFLFFELIETSLNITSLIATIVDTLERLQTLFE--SRTPFMT------LYMSSVCLRSIGILQRHQPVLFTMSDLPNRLFPALIAQVRQVREPTQCGPFERCVLAYLNDLFTSNAQIKSHFASIYNKAHPKVAALFRSVEPSEGLATFDQDYASDLLKAAGSDYPSLFRAY-------ADDLRNNPNSRFSFVCRAIIFVCQATTLERVNYLCGLCAELTSHCGDLTPEWLGALYAVIAPRPYRHGYGPIV----SAVEPGDMNMYDSVSSLIGTLLFRRCMTISDFLCRVICPAMAQGLVQP--VGPQLEPSIRLACHILHRLFTAESSASTIQANMSALTPGHEPPTSAMATANTTSTSATDLSTPPFRISEPLLLTGALQKVTPELLVDVLKMLMVHNDKACSEDQVQSGMHVADDATEGSDSDVGQADDEVHDEEHSHRRLTGGKAIHPIVRRFLESGILPTVIELRNLPLIGLIQLVLREICSVPWVRERFFRMPSDRWTRENVLIDRKFSPTQARRLLHVIFHPFDITWSDTSS---LATSMCQVLSSLDLWTLRCALVKFQLLYTQIRLSQQKDVLDSVGQAIVRGFQTQALNWLKANGSGMSADVCLAPIGGISRFELEENDPV--------WLVPALIAKLP-RQLKAQIVTGALEILQGIKHFWKHKNDEDKEGELLKHSIVLAHPAFFRLLQVCMAEIDP----IDKLYEQVGYFVENAHDTEDRVPDNLRTRQVVQECLRLRLTLVGQCFKALQKEHELTTDWSLLLTKLISHGVIEPESN-TTLFYMVYDMLQSLVHTMAARSGVEGKHYQNLAKKIRRELSRRPSY-GIEQIR-LLLPPLKAACTVIVTG-----HNAQRLSASGSSGTSEGGGPGSGANKSGGIGKVSTSKGAGKGGGSSHHGGPRDNTFRRPGKKRGFTIIGKERLAPWDLQDPSKQAILLSMHGATSIEAIPSRTEEQANRLIRHDHFIRLRRPPEFYLTPVYPEEEDAKVQD-KRSDATEQPTLGPPPS 1896
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. TrEMBL
Match: A0A419PSG5 (Mediator of RNA polymerase II transcription subunit 12-like protein OS=Clonorchis sinensis OX=79923 GN=MED12L PE=4 SV=1) HSP 1 Score: 752.281 bits (1941), Expect = 0.000e+0 Identity = 627/1976 (31.73%), Postives = 940/1976 (47.57%), Query Frame = 2
Query: 29 MSYYHSLETHPLKCLKQTEGYNSHKVLLGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVVEEHESAKDIGFEFISKPFLT---DLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNE----QCSDDEQM------------------------------MKFYLPFLLYFGDRFKESEILTRKLLHGLCNSV-NLLLTNNK----------HPDRS----ITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNL--NGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVVELLDRYDYNCYKDSSVFEGLCTVVV---SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDNI-HQNQSH----QSIQNCLVEFLDTKS----PIIDSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPI-----------------GGFLSVAHNXX------------XXXHRKSPELDRMSTGDNPDSVRSE---------CSGLNQILPSIP----IVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEK-SRKKSRRDPREESM--------------------------------LIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSL-------------------------------NIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRSCPTFVMNMK--KLENVFRNIKPDK-----DRSSSIDYVESVGMD---LFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVSNDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNST--AN----------------------------SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYF------DLTENNQVSFGPPFRRSIDTEESF--------IHMKIWNF----------TLR----------VLREICCVSWVRIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQ--QANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCLAKDDNRSEFLKSLADQIEYYIDNAKETE-KMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIKFFQ-MIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQ-------------YRLTTAEKSG---------------------------------KQGCAVQRKERINPWEVIEGIKNLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYYTS--FPEILPEDIKDPSISDPMEIINSSGPPS 5056
MS + SLE LK K+++ PPDVY Q +QKEDL++E VR+G+ Y KPV +E++S + FLT L F V+ K ++ + QD K+ A+ ++ +P ++K++ W +LS + P +++ +R+PY K+++L E+ ++VPI+RA+W I + +H Q E+ K+K R V S+W + + L L ++L + E +++YL L++A+YD D+ DH EVL WL E Q S+DE +KF+L +LL FG RF E+E++ R+LL C + +++L+ ++ HP+ + + + Y E SC HR+V+ LS +I L L CP A V+N+I +L GSPLD++P + +ALP P G E R + +E I+ RS E W ++F + LIKV+++LDR DY+ K+ + E L + ++ + ++L+ LCEW+VS R G +R +VA +++ + H QS Q +Q L++FLDT + P Q D+EP RNLVCLF ELI+RE+F + Y+ MIARG+F +V PL G F +V++ + S + S + DR S DNPDSVRSE C G P P + + H YL HFP+P ++ Y HE N R Q LY + R RD + +R+L +DI K++T++ Y+ D++ E RKKS+ RE S LI+KL E I SRF CL+Y+DMECV+SQC PT L N +LAN L + S +++P P I LIE S N + LI I + L L E SR +T YMS + IG L + Q VL TMSD R+F + R G RC A + F S A ++S + N K+ +FR+++P + D+ + D +++ G D LF+ +L+ N N RFS V ++ V Q T ++++ + + E S+ L+ EW+ A+Y+++ P GY V S + D+ Y+++S+LI T+L R+C SDFL RVIC A+AQG+ Q V P + P+ RLA +IL RLFT E ST AN S F+ + LL+ +LQKVT ELLVD+LKML VH+DK +DQ D TE + G D E S IH + F LR VLREIC V WVR RF + R R+NVLID+ S +QAR LL++I HP D W + + + +M + ++L++W+L +K QLL TQI ++KDV+++V + I+ F+ QA +AN + D + P +L+P+LI KLP K Q++ A E L+ KHF HKN +DKE +L K S++L +P F LL VC+A+ D + L +Q+ Y+++NA +TE ++PD+LR + ++ ++ RL LVG F +Q+ EL DW LLL+KLI +GV+E S+ + LFY V DM+ +L+HT+ + K +Q + KK+R+E+ + +Y G+E I+ LLP K VIVT H +Q+ + A KSG K+G + KER+ PW++ + K LS A S + EE AN +I HDH +L RP +Y + +PE ++D SD E PPS
Sbjct: 1 MSAFPSLENRSLK--KKSDC---------PPDVYNQRDEQKEDLMSEDFVRDGYKYIKPVRDEYDSCRK------ESKFLTVNDSLWKFYHDVLAKKYDCSTYQDLKKKS---ASNVRET-IVPVVDKNQ--ANAWFRELSGSTPL-QILGRRVPYSKDKQEILSELVAHKVPISRAVWLINLILLHTPAQPENAKRKQRPTVHP-SEWTSNICQMLERNL----VQLCSES--GEQPSVEEDWDYLFTLLLALYDSDVADHWEVLLWLTKRAEGLWKQPSEDEAAPTQQQYSNYDNNGDEPLPTETIEETNMLNNVKFFLFYLLKFGRRFTENELIARRLLFWCCGTFRSIVLSESRVPAADNQAGNHPNNTEMQLVLEEYLETCSCPLHRSVVLSLSSMITCLILSCPSAAVWNSIPTGTDHLYLEGSPLDVIPYSTAALPMPQGPETTEIRQCLFDVENVIITRSQLAEVGWNRQAFTDVSGEEMERLIKVLDILDRQDYHSVKEHNPMEALFNRIFNDDAINVDTAILVTTLCEWAVSVHRVGIYRSVIVACLLEQLTHSFQSDPNPFQMLQQTLLDFLDTFTSNLPPYSTDQAPVDNEPMRNLVCLFAELIDREVFDHDIYVRRMIARGVF-AVECHPLATSTVTESHTATLTLSTSTHGKFQAVSNTTLLSNLPNNVTTQCSVASEMSEDNDRCSV-DNPDSVRSEAGFPSVTTSCCGYVTSAPHHPASESLTGPARCSPHFHYLTHFPLPQDESYSHEENQRYQLLYGSLRARDRARSRIRQLVRDIVKIFTRKFYLIDVVHGEMCKRKKSKDREREVSTAPVANMPSSSGHRVVAVTTTGGGSGGASDDAHLIDKLHEDIMSRFICLSYHDMECVISQCTPTFTKVLSGCNGQGNPTVIGDDYHSGSTLGMANPPSPPNNAGVLAN-LTNQSPIYMPVPNSIFLFFELIETSLNITSLIATIVDTLERLQTLFE--SRTPFMT------LYMSSVCLRSIGILQRHQPVLFTMSDLPNRLFPALIAQVRQVREPTQCGPFERCVLAYLNDLFTSNAQIKSHFASIYNKAHPKVAALFRSVEPSEGLATFDQDYASDLLKAAGSDYPSLFRAY-------ADDLRNNPNSRFSFVCRAIIFVCQATTLERVNYLCGLCAELTSHCGDLTPEWLGALYAVIAPRPYRHGYGPIV----SAVEPGDMNMYDSVSSLIGTLLFRRCMTISDFLCRVICPAMAQGLVQP--VGPQLEPSIRLACHILHRLFTAESSASTIQANMSALTPGHEPPTSAMATANTTSTSATDLSTPPFRISEPLLLTGALQKVTPELLVDVLKMLMVHNDKACSEDQVQSGMHVADDATEGSDSDVGQADDEVHDEEHSHRRLTGGKAIHPIVRRFLESGILPTVIELRNLPLIGLIQLVLREICSVPWVRERFFRMPSDRWTRENVLIDRKFSPTQARRLLHVIFHPFDITWSDTSS---LATSMCQVLSSLDLWTLRCALVKFQLLYTQIRLSQQKDVLDSVGQAIVRGFQTQALNWLKANGSGMSADVCLAPIGGISRFELEENDPV--------WLVPALIAKLP-RQLKAQIVTGALEILQGIKHFWKHKNDEDKEGELLKHSIVLAHPAFFRLLQVCMAEIDP----IDKLYEQVGYFVENAHDTEDRVPDNLRTRQVVQECLRLRLTLVGQCFKALQKEHELTTDWSLLLTKLISHGVIEPESN-TTLFYMVYDMLQSLVHTMAARSGVEGKHYQNLAKKIRRELSRRPSY-GIEQIR-LLLPPLKAACTVIVTG-----HNAQRLSASGSSGTSEGGGPGSGANKSGGIGKVSTSKGAGKGGGSSHHGGPRDNTFRRPGKKRGFTIIGKERLAPWDLQDPSKQAILLSMHGATSIEAIPSRTEEQANRLIRHDHFIRLRRPPEFYLTPVYPEEEDAKVQD-KRSDATEQPTLGPPPS 1896
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. TrEMBL
Match: A0A4S2MCS9 (Med12 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002356 PE=4 SV=1) HSP 1 Score: 750.355 bits (1936), Expect = 0.000e+0 Identity = 624/1977 (31.56%), Postives = 935/1977 (47.29%), Query Frame = 2
Query: 29 MSYYHSLETHPLKCLKQTEGYNSHKVLLGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVVEEHESAKDIGFEFISKPFLT---DLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDHEYEMTVSE-FEYLMRLMVAMYDEDLLDHTEVLQWLVSTNE----QCSDDEQM------------------------------MKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLL-----------TNNKHPDRS----ITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNL--NGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVVELLDRYDYNCYKDSSVFEGLCTVVV---SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDNI-HQNQSH----QSIQNCLVEFLDTKS----PIIDSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPI-----------------GGFLSVAHNXX------------XXXHRKSPELDRMSTGDNPDSVRSE---------CSGLNQILP----SIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEK-SRKKSRRDPREESM--------------------------------LIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSL-------------------------------NIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRSCPTFVMNMK--KLENVFRNIKPDK-----DRSSSIDYVESVGMD---LFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVSNDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNSTAN------------------------------SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYF------DLTENNQVSFGPPFRRSIDTEESF--------IHMKIWNF----------TLR----------VLREICCVSWVRIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQ--QANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCLAKDDNRSEFLKSLADQIEYYIDNAKETE-KMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIKFFQ-MIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQ-------------YRLTTAEKSG---------------------------------KQGCAVQRKERINPWEVIEGIKNLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYYTS--FPEILPEDIKDPSISDPMEIINSSGPPS 5056
MS + SLE LK K+++ PPDVY Q +QKEDL++E VR+G+ Y KPV +E++S + FLT L F V+ K ++ + QD K+ + + + + + +P ++K++ W +L+ + P +++ +R+PY K+++L E+ ++VPI+RA+W I + +H Q E+ K+K R V S+W + + L L M+ + + +V E ++YL L++A+YD D+ DH EVL WL E Q S+DE +KF+L +LL FG RF E+E++ R+LL C + +++ + HP+ + + + Y E SC HR V+ LS +I L L CP A V+N+I +L GSPLD++P + +ALP P G E R + +E I+ RS E W ++F + LIKV+++LDR DY+ K+ + E L + ++ + ++L+ LCEW+VS R G +R LVA +++ + H QS Q +Q L++FLDT + P Q D+EP RNLVCLF ELI+RE+F + Y+ MIARG F +V PL G F +V++ + S + S + DR S DNPDSVRSE C G P S P+ + H YL HFP+P ++ Y HE N R Q LY + R RD + +R+L +DI K++T++ Y+ D++ E RKKS+ RE S LI+KL E I SRF CL+Y+DMECV+SQC PT L N +LAN L + S +++P P I LIE S N + LI I + L L E SR +T YMS + IG L + Q VL TM D R+F + R G RC A + F S A ++S + N K+ +FR+++P + D+ + D + + G D LF++ +L+ N N RFS V ++ V Q T ++++ + + E S+ L+ EW+ A+Y+++ P GY V S + D+ Y+++S+LI T+L R+C SDFL RVIC A+AQG+ Q V P + P+ RLA +IL RLFT E ST S F+ + LL+ +LQKVT ELLVD+LKML VH+DK +DQ D TE + G + D E S IH + F LR VLREIC V WVR RF + R R+NVLID+ S +QAR LL++I HP D W + + + M + ++L++W+L +K QLL TQI ++KDV+++V + I+ F+ QA +AN + D + P +L+P+LI KLP K Q++ A E L+ KHF HKN +DKE +L K S++L +P F LL VC+A+ D + L +Q+ Y+++NA +TE ++PD+LR + ++ ++ RL LVG F +Q+ EL DW LLL+KLI +GV+E S+ + LFY V DM+ +L+HT+ + K +Q + KK+R+E+ + +Y G+E I+ LLP K VIVT H +Q+ + A KSG K+G + KER+ PW++ + K LS A S + EE AN +I HDH +L RP +Y + +PE ++D SD E PPS
Sbjct: 1 MSAFPSLENRSLK--KKSDC---------PPDVYNQRDEQKEDLMSEDFVRDGYKYIKPVRDEYDSCRK------ESKFLTVNDSLWKFYHDVLAKKYDCSTYQDLKKK--SSSNIRETI--VPVVDKNQ--ANAWFRELAGSTPL-QILGRRVPYSKDKQEILSELVAHKVPISRAVWLINLILLHTPAQPENAKRKQRPTVHP-SEWTSNICQMLERNL-------MQLCSESGEQPSVEEDWDYLFTLLLALYDSDVADHWEVLLWLAKRAEGLWKQPSEDEAPPTQQQYSNYDNSSDDPLPSETVEETNMLNNVKFFLFYLLKFGRRFTENELIARRLLFWCCGTFRIIVLSESRVPAADNQSGNHPNNTGMQLVLEEYLETCSCPLHRNVVLSLSSMITCLILSCPSAAVWNSIPTGTDHLYLEGSPLDVIPYSTAALPMPQGPETTEIRQCLFDVENVIITRSQLAEVGWNRQAFTDVSGEEMERLIKVLDILDRQDYHSVKEHNPTEALFNRIFNDDAINVDTAILVTTLCEWAVSVHRVGIYRSVLVACLLEQLTHSFQSDPNPFQMLQQTLLDFLDTFTSNLPPYTTDQAPVDNEPMRNLVCLFAELIDREVFDHDIYVRRMIARGAF-AVECHPLATSAVTESHTATLTLSTSTHGKFQAVSNTTLLTNLPNNVTTQCSVASEMSEDNDRCSV-DNPDSVRSEAGFPSVTTSCCGYAASAPHHPASEPLTGPARCSPHFHYLTHFPLPQDESYSHEENQRYQLLYGSLRARDRARSRIRQLVRDIVKIFTRKFYLIDVVHGEMCKRKKSKDRERELSTAPVANMPSSSGHRVVAVTTTGGGSGGASDDAHLIDKLHEDIMSRFICLSYHDMECVISQCTPTFTKVLSGCNGQGNPTAIGDEYHSGSTLGMANPPSPPNNAGVLAN-LTNQSPIYMPVPNSIFLFFELIETSLNITSLIATIVDTLERLQTLFE--SRTPFMT------LYMSSVCLRSIGILQRHQPVLFTMGDLPNRLFPALIAQVRQVREPTQCGPFERCVLAYLNDLFTSNAQIKSHFASIYNKAHPKVAALFRSVEPSEGLATFDQDYASDLLRAAGSDYPSLFRVY-------ADDLRNNPNSRFSFVCRAIIFVCQATTLERVNYLCGLCAELTSHCGDLTPEWLGALYAVIAPRPYRHGYGPIV----SAVEPGDMNMYDSVSSLIGTLLFRRCMTISDFLCRVICPAMAQGLVQP--VGPQLEPSIRLACHILHRLFTAESSASTLQTNTNALTPGHEPPASAIATANTTSTSATDLSTPPFRISEPLLLTGALQKVTPELLVDVLKMLMVHNDKACSEDQVQSGMHVADDATEGSDSDVGQVDDEAHDEEHSHRRLTVGKAIHPIVRRFLESGILPTVIELRNLPLIGLIQLVLREICSVPWVRERFFRMPSDRWTRENVLIDRKFSPTQARRLLHVIFHPFDLTWSDTSS---LAAAMCQVLSSLDLWTLRCALVKFQLLYTQIRLSQQKDVLDSVGQAIVRGFQTQALNWLKANGSGMSADVCLAPIGGISRFELEENDPV--------WLVPALIAKLP-RQLKAQIVTGALEILQGIKHFWKHKNDEDKEGELLKHSIVLAHPAFFRLLQVCMAEIDP----IDKLYEQVGYFVENAHDTEDRVPDNLRTRQVVQECLRLRLTLVGQCFKALQKEHELTTDWSLLLTKLISHGVIEPESN-TTLFYMVYDMLQSLVHTMAARSGVEGKHYQNLAKKIRRELSKRPSY-GIEQIR-LLLPPLKAACTVIVTG-----HNAQRLSASGSSGTSESGGPGSGANKSGGIGKVSTSKGAGKGGGSSHHGGPRDSGFRRPGKKRGFTIIGKERLAPWDLQDPSKQAILLSMHGATSIEAIPSRTEEQANRLIRHDHFIRLRRPPEFYLAPVYPEEEDAKVQD-KRSDATEQPTLGPPPS 1896
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. TrEMBL
Match: A0A1S8X198 (Transcription mediator subunit Med12 (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_03838 PE=4 SV=1) HSP 1 Score: 742.265 bits (1915), Expect = 0.000e+0 Identity = 623/1976 (31.53%), Postives = 938/1976 (47.47%), Query Frame = 2
Query: 29 MSYYHSLETHPLKCLKQTEGYNSHKVLLGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVVEEHESAKDIGFEFISKPFLT---DLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNE----QCSDDEQM------------------------------MKFYLPFLLYFGDRFKESEILTRKLLHGLCNSV-NLLLTNNK----------HPDRS----ITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHN--LNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVVELLDRYDYNCYKDSSVFEGLCTVVV---SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDNI-HQNQSH----QSIQNCLVEFLDTKS----PIIDSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPI-----------------GGFLSVAHNXX------------XXXHRKSPELDRMSTGDNPDSVRSE---------CSGLNQILPSIP----IVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEK-SRKKSRRDPRE--------------------------------ESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSL-------------------------------NIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRSCPTFVMNMK--KLENVFRNIKPDK-----DRSSSIDYVESVGMD---LFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVSNDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNST--AN----------------------------SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQD--QDYF----DLTENNQVSFGPPFRRSIDTEESF--------IHMKIWNF----------TLR----------VLREICCVSWVRIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQ--QANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCLAKDDNRSEFLKSLADQIEYYIDNAKETE-KMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIKFFQ-MIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQY---------------------------------------------RLTTAEKSGKQ-GCAVQRKERINPWEVIEGIKNLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYYTS--FPEILPEDIKDPSISDPMEIINSSGPPS 5056
MS + SLE LK K+++ PPDVY Q +QKEDL++E VR+G+ Y KPV +E++S + FLT L F V+ K ++ + QD K+ A+ ++ +P ++K++ W +L+ + P +++ +R+PY K+++L E+ ++VPI+RA+W I + +H Q E+ K+K R V S+W + + L L ++L + E +++YL L++A+YD D+ DH EVL WL E Q S+DE +KF+L +LL FG RF E+E++ R+LL C + +++L+ ++ HP+ I + Y E SC HR+V+ LS +I L L CP A V+N+I + L GSPLD++P + +ALP P G E R + +E I+ RS E W ++F + LIKV+++LDR DY+ K+ + E L + ++ + ++L+ LCEW+VS R G +R +VA +++ + H +S Q +Q L++FLDT S P + D+EP RNLVCLF ELI+RE+F + Y+ MIARG+F +V PL G F +V++ + S + S + DR S DNPDSVRSE C G P P + + H YL HFP+P ++ Y HE N R Q LY + R RD + +R+L +DI K++T++ Y+ D++ E RKKS+ RE ++ LI+KL E I SRF CL+Y+DMECV+SQC PT L N I+AN L S S +++P P I LIE S N + LI I + L L E SR +T YMS + IG L + Q VL TMSD R+F + R G RC A + F S A ++S + N K+ +FR+++P + D+ + D +++ G D LF+ +L+ N N RFS V ++ V Q T ++++ + + E S+ L+ EW+ A+Y+++ P GY V S++ D+ Y+++S+LI T+L R+C SDFL RVIC A+AQG+ Q V P + P+ RLA +IL RLFT E ST AN S F+ + LL+ +LQKVT ELLVD+LKML VH+DK +D Q D TE + G + D E S IH + F LR VLREIC V WVR RF + R R+NVLID+ S +QAR LL++I HP D W + + + M + ++L++W+L +K QLL TQI ++KDV+++V + I+ F+ QA +AN + D + P +L+P+LI KLP K Q++ A E L+ KHF HKN +DKE +L K S++L +P F LL VC+A+ D + L +Q+ Y+++NA +TE ++PD+LR + ++ ++ RL LVG F +Q+ E DW LLL+KLI +GV+E S+ + LFY V DM+ +L+HT+ + K +Q + KK+R+E+ + +Y G+E I+ LLP K VIVT H +Q+ R + + GK+ G + KER+ PW++ + K LS A S + EE AN +I HDH +L RP +Y + +PE +D SD E PPS
Sbjct: 1 MSAFPSLENRSLK--KKSDC---------PPDVYNQRDEQKEDLMSEDFVRDGYKYIKPVRDEYDSCRK------ESKFLTVNDSLWKFYHDVLAKKYDCSTYQDLKKKS---ASNVRET-IVPVVDKNQ--ANAWFRELAGSTPL-QILGRRVPYSKDKQEILSELVAHKVPISRAVWLINLILLHTPAQPENAKRKQRPTVHP-SEWTSNICQMLERNL----VQLCSES--GEQPSVEEDWDYLFTLLLALYDSDVADHWEVLLWLTKRAESLWKQPSEDEAAPTQQQYSNYDNNSDEPLPTETIEETNVLNNVKFFLFYLLKFGRRFTENELIARRLLFWCCGTFRSIVLSESRVPAADNQAGNHPNNPEMQLILEEYLETCSCPLHRSVVLSLSSMITCLILSCPSAAVWNSIPTGTDHSYLEGSPLDVIPYSTAALPMPRGPETTEIRQCLFDVENVIITRSQLAEVGWNRQAFTDVSGEEMERLIKVLDILDRQDYHSVKEHNPMEALFNRIFNDDAINVDTAILVTTLCEWAVSVHRVGIYRSVIVACLLEQLTHSFESDPNPFQMLQQTLLDFLDTFSSSLPPYSTDRALVDNEPMRNLVCLFAELIDREVFDHDIYVRRMIARGVF-AVECHPLAASAVTESHTATLTFSTSTHGKFQAVSNTTLLSNLPNNVTTQCSVASEMSEDNDRCSV-DNPDSVRSEVGFPSVTTSCCGYATSAPHHPASESLTGPARCSPHFHYLTHFPLPQDESYSHEENQRYQLLYGSLRARDRARSRIRQLVRDIVKIFTRKFYLIDVVHGEMCKRKKSKDREREVSTAPVANMPSSSGHRVVAVSATGGGSGGVSDDAHLIDKLHEDIMSRFICLSYHDMECVISQCTPTFTKVLSGCNGQGNPTVIGDDYHSSSTLGMANPPSPPNNAGIVAN-LTSQSTIYMPVPNSIFLFFELIETSLNITSLIATIVDTLERLQTLFE--SRTPFMT------LYMSSVCLRSIGILQRHQPVLFTMSDLPNRLFPALIAQVRQVREPTQCGPFERCVLAYLNDLFTSNAQIKSHFASIYNKAHPKVAALFRSVEPSEGLATFDQDYASDLLKAAGSDYPSLFRAY-------ADDLRNNPNSRFSFVCRAIIFVCQATTLERVNYLCGLCAELTSHCGDLTPEWLGALYAVIAPRPYRHGYGPIV----SVVEPGDMNMYDSVSSLIGTLLFRRCMTISDFLCRVICPAMAQGLVQP--VGPQLEPSIRLACHILHRLFTAESSASTIQANMSALTPGHEPSASAIATANTTSTSATDLSTPPFRISEPLLLTGALQKVTPELLVDVLKMLMVHNDKACSEDLVQSGMHMGDDATEGSDSDVGQADDEAHDEEHSHRRFTGGKAIHPIVRRFLESGILPTVIELRNLPLIGLIQLVLREICSVPWVRERFFRMPSDRWTRENVLIDRKFSPTQARRLLHVIFHPFDLTWSDTSS---LATAMCQVLSSLDLWTLRCALVKFQLLYTQIRLSQQKDVLDSVGQAIVRGFQTQALNWLKANGSGMSADVCLAPIGGISRFELEENDPV--------WLVPALIAKLP-RQLKAQIVTGALEILQGIKHFWKHKNDEDKEGELLKHSIVLAHPAFFRLLQVCMAEIDP----VDKLYEQVGYFVENAHDTEDRVPDNLRTRQVVQECLRLRLTLVGQCFKALQKEHEPTTDWSLLLTKLISHGVIEPESN-TTLFYMVYDMLQSLVHTMAARSGVEGKHYQNLAKKIRRELSRRPSY-GIEQIR-LLLPPLKAACTVIVTG-----HNAQRLSASGSSGTSDGGGSGSGANKSGGIGKVSTSKGAGKGGGSGHHGGPRDSAFRRPGKKRGFTIIGKERLAPWDLQDPSKQAILLSMHGATSIEAIPSRTEEQANRLIRHDHFIRLRRPPEFYLTPVYPEEEDAKAQD-KRSDATEQPTLGPPPS 1896
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. TrEMBL
Match: A0A074Z6U9 (Med12 domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_10348 PE=4 SV=1) HSP 1 Score: 735.717 bits (1898), Expect = 0.000e+0 Identity = 625/1996 (31.31%), Postives = 940/1996 (47.09%), Query Frame = 2
Query: 11 YLN------FISMSYYHSLETHPLKCLKQTEGYNSHKVLLGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVVEEHESAKDIGFEFISKPFLT---DLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVSAMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNE----QCSDDEQM------------------------------MKFYLPFLLYFGDRFKESEILTRKLLHGLCNSV-NLLLTNNK----------HPDRS----ITDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHN--LNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVVELLDRYDYNCYKDSSVFEGLCTVVV---SLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDNI-HQNQSH----QSIQNCLVEFLDTKS----PIIDSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPI-----------------GGFLSVAHNXX------------XXXHRKSPELDRMSTGDNPDSVRSE---------CSGLNQILPSIP----IVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEK-SRKKSRRDPRE--------------------------------ESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSL-------------------------------NIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRSCPTFVMNMK--KLENVFRNIKPDK-----DRSSSIDYVESVGMD---LFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGN--------ASPGYEQFVNKFNSLLVSNDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNST--AN----------------------------SVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQD--QDYF----DLTENNQVSFGPPFRRSIDTEESF--------IHMKIWNF----------TLR----------VLREICCVSWVRIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQ--QANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCLAKDDNRSEFLKSLADQIEYYIDNAKETE-KMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIKFFQ-MIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQY---------------------------------------------RLTTAEKSGKQ-GCAVQRKERINPWEVIEGIKNLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYYTS--FPEILPEDIKDPSISDPMEIINSSGPPS 5056
YLN + MS + SLE LK K+++ PPDVY Q +QKEDL++E VR+G+ Y KPV +E++S + FLT L F V+ K ++ + QD K+ A+ ++ +P ++K++ W +L+ + P +++ +R+PY K+++L E+ ++VPI+RA+W I + +H Q E+ K+K R V S+W + + L L ++L + E +++YL L++A+YD D+ DH EVL WL E Q S+DE +KF+L +LL FG RF E+E++ R+LL C + +++L+ ++ HP+ I + Y E SC HR+V+ LS +I L L CP A V+N+I + L GSPLD++P + +ALP P G E R + +E I+ RS E W ++F + LIKV+++LDR DY+ K+ + E L + ++ + ++L+ LCEW+VS R G +R +VA +++ + H +S Q +Q L++FLDT S P + D+EP RNLVCLF ELI+RE+F + Y+ MIARG+F +V PL G F +V++ + S + S + DR S DNPDSVRSE C G P P + + H YL HFP+P ++ Y HE N R Q LY + R RD + +R+L +DI K++T++ Y+ D++ E RKKS+ RE ++ LI+KL E I SRF CL+Y+DMECV+SQC PT L N I+AN L S S +++P P I LIE S N + LI I + L L E SR +T YMS + IG L + Q VL TMSD R+F + R G RC A + F S A ++S + N K+ +FR+++P + D+ + D +++ G D LF+ +L+ N N RFS V ++ V Q T ++++ + + E S+ L+ EW+ A+Y+++ P A Y S + D+ Y+++S+LI T+L R+C SDFL RVIC A+AQG+ Q V P + P+ RLA +IL RLFT E ST AN S F+ + LL+ +LQKVT ELLVD+LKML VH+DK +D Q D TE + G + D E S IH + F LR VLREIC V WVR RF + R R+NVLID+ S +QAR LL++I HP D W + + + M + ++L++W+L +K QLL TQI ++KDV+++V + I+ F+ QA +AN + D + P +L+P+LI KLP K Q++ A E L+ KHF HKN +DKE +L K S++L +P F LL VC+A+ D + L +Q+ Y+++NA +TE ++PD+LR + ++ ++ RL LVG F +Q+ E DW LLL+KLI +GV+E S+ + LFY V DM+ +L+HT+ + K +Q + KK+R+E+ + +Y G+E I+ LLP K VIVT H +Q+ R + + GK+ G + KER+ PW++ + K LS A S + EE AN +I HDH +L RP +Y + +PE +D SD E PPS
Sbjct: 8 YLNSSPRPIYREMSAFPSLENRSLK--KKSDC---------PPDVYNQRDEQKEDLMSEDFVRDGYKYIKPVRDEYDSCRK------ESKFLTVNDSLWKFYHDVLAKKYDCSTYQDLKKKS---ASNVRE-TIVPVVDKNQ--ANAWFRELAGSTPL-QILGRRVPYSKDKQEILSELVAHKVPISRAVWLINLILLHTPAQPENAKRKQRPTVHP-SEWTSNICQMLERNL----VQLCSES--GEQPSVEEDWDYLFTLLLALYDSDVADHWEVLLWLTKRAESLWKQPSEDEAAPTQQQYSNYDNNSDEPLPTETIEETNVLNNVKFFLFYLLKFGRRFTENELIARRLLFWCCGTFRSIVLSESRVPAADNQAGNHPNNPEMQLILEEYLETCSCPLHRSVVLSLSSMITCLILSCPSAAVWNSIPTGTDHSYLEGSPLDVIPYSTAALPMPRGPETTEIRQCLFDVENVIITRSQLAEVGWNRQAFTDVSGEEMERLIKVLDILDRQDYHSVKEHNPMEALFNRIFNDDAINVDTAILVTTLCEWAVSVHRVGIYRSVIVACLLEQLTHSFESDPNPFQMLQQTLLDFLDTFSSSLPPYSTDRALVDNEPMRNLVCLFAELIDREVFDHDIYVRRMIARGVF-AVECHPLAASAVTESHTATLTFSTSTHGKFQAVSNTTLLSNLPNNVTTQCSVASEMSEDNDRCSV-DNPDSVRSEVGFPSVTTSCCGYATSAPHHPASESLTGPARCSPHFHYLTHFPLPQDESYSHEENQRYQLLYGSLRARDRARSRIRQLVRDIVKIFTRKFYLIDVVHGEMCKRKKSKDREREVSTAPVANMPSSSGHRVVAVSATGGGSGGVSDDAHLIDKLHEDIMSRFICLSYHDMECVISQCTPTFTKVLSGCNGQGNPTVIGDDYHSSSTLGMANPPSPPNNAGIVAN-LTSQSTIYMPVPNSIFLFFELIETSLNITSLIATIVDTLERLQTLFE--SRTPFMT------LYMSSVCLRSIGILQRHQPVLFTMSDLPNRLFPALIAQVRQVREPTQCGPFERCVLAYLNDLFTSNAQIKSHFASIYNKAHPKVAALFRSVEPSEGLATFDQDYASDLLKAAGSDYPSLFRAY-------ADDLRNNPNSRFSFVCRAIIFVCQATTLERVNYLCGLCAELTSHCGDLTPEWLGALYAVIAPRPYDMAVLIIAPRPYRHGYGPIVSDVEPGDMNMYDSVSSLIGTLLFRRCMTISDFLCRVICPAMAQGLVQP--VGPQLEPSIRLACHILHRLFTAESSASTIQANMSALTPGHEPSASAIATANTTSTSATDLSTPPFRISEPLLLTGALQKVTPELLVDVLKMLMVHNDKACSEDLVQSGMHMGDDATEGSDSDVGQADDEAHDEEHSHRRFTGGKAIHPIVRRFLESGILPTVIELRNLPLIGLIQLVLREICSVPWVRERFFRMPSDRWTRENVLIDRKFSPTQARRLLHVIFHPFDLTWSDTSS---LATAMCQVLSSLDLWTLRCALVKFQLLYTQIRLSQQKDVLDSVGQAIVRGFQTQALNWLKANGSGMSADVCLAPIGGISRFELEENDPV--------WLVPALIAKLP-RQLKAQIVTGALEILQGIKHFWKHKNDEDKEGELLKHSIVLAHPAFFRLLQVCMAEIDP----VDKLYEQVGYFVENAHDTEDRVPDNLRTRQVVQECLRLRLTLVGQCFKALQKEHEPTTDWSLLLTKLISHGVIEPESN-TTLFYMVYDMLQSLVHTMAARSGVEGKHYQNLAKKIRRELSRRPSY-GIEQIR-LLLPPLKAACTVIVTG-----HNAQRLSASGSSGTSDGGGSGSGANKSGGIGKVSTSKGAGKGGGSGHHGGPRDSAFRRPGKKRGFTIIGKERLAPWDLQDPSKQAILLSMHGATSIEAIPSRTEEQANRLIRHDHFIRLRRPPEFYLTPVYPEEEDAKAQD-KRSDATEQPTLGPPPS 1927
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Cavefish
Match: med12 (mediator complex subunit 12 [Source:NCBI gene;Acc:566632]) HSP 1 Score: 347.051 bits (889), Expect = 6.728e-96 Identity = 397/1434 (27.68%), Postives = 635/1434 (44.28%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVS-AMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDH-----------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVN-------LLLTNNKHPDRSI--------------------------TDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPIIDSQISADSE--PFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXXXHRK-SPELDRMSTGD-NPDSVRSECSGLNQ-----ILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIV---ETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN-------STANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSD-----KGRLQDQDYFDLTENNQVSFGPPFRR-SIDTEESFIHMKIWNFTLRVLREICCVSWV--RIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAE 3928
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F + +++ ++I + N DT KRK V KD + +S+ I W L+ T P +L K++P F KKE+V + KY VP+ R+ W IK++ A HA I K K R +D +W + L E+L + + R + E E + ++EY +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + +N L L+ HP SI TDFY C HR V+F LS ++ S+ L CP A+V++ N GSPLDLLP A S LP P G N R + ++E+ I +R AVE +W SF+ E TA I V E+LD + + S+ + L + D H + ++ LLCEW+V R+G HR +VA++++ I + +S Q+ L++FLDT++P++ ++ +SE F NLV LF ELI ++FS N YM +I+RG S ++LP P + + + HNSS++ SP + + G +P+ E G + + P+ P V Y RH+QY HFPIP + HE N R LY + RD + ++++ KDI K+ ++ + + RK+S+ + AE I S+F+ L+++D V SQ + + ++ + LP I + +L+E S N S LI + LN + L+E + L+ + SL SY + +CI+ L ++ S L+ D ++F G+ ++ ++ V+ RC A + + SC+ L+S F K++N ++ NI P D+ ID + + +MV N + R+S V N L+ V C D R+N I + E + LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D V CVA+ A +Q S P RL IL LF Q+N S ++V D +LL++S + + +LK + + D G D+ E++ S R SI+T ++ K VL+ IC WV R S S ++D VL+ N QA+ LL +IC+P L + + R N++ W++ +++QL++ Q E ++EN++K I +F+ AE
Sbjct: 19 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVNFN------PSKISSNFSSIIAEKLRCNTFPDTGKRKPQVNQ--KDNFWL-VTARSQSSINIWFTDLAGTKPLTQLA-KKVPIFSKKEEVFGYLAKYSVPVMRSAWMIKMTCAYHAAI--TETKVKKRHVIDPCIEWTQIITKYLWEQLQKV-AEFYRQSPSQGCGSPLPATPAEVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLQYSGE-FVQSAYLSRRLAYFCTRRLNLLLSDGSLGLSTGGHPPHSISGQPGNALPPTPTSQPAGGNQPQTPFTDFYI----CPQHRPVVFGLSCMLQSIVLCCPSALVWHYSLTDSRNKTGSPLDLLPIAPSNLPMPGGNSTFNQQVRAKVREIEEQIKERGQAVEFRW---SFDKCQETTAGFTIGRVLHTLEVLDNHSFEKSDFSNSLDSLYNRIFGSGQSKDGHEMSPDDDAVVTLLCEWAVCCKRSGRHRAMVVAKLLEKRQTEIEAERCGESEVVDEKGSVSSGSLSAATVPVFQDVLLQFLDTQAPVL-TEPGNESERVEFSNLVLLFCELIRHDVFSHNIYMCTLISRGDLASDSHLPRPRSPSDEPSDESERKEQDTGSSVKMEDTGLSEPMEIEHNSSANFDEMFSPPMHGEAKGSPSPEKAAPEQDGKSTAKEKCMDPAFPQV-YEQ-PRHIQYATHFPIPQEESASHECNQRQVVLYGVGKQRDEARHAIKKITKDILKVLNRKSTAETGGEEGQKRKRSKPE-------AFPTAEDIFSKFQHLSHFDQHQVTSQVSRNVLEQITSFAL-------GMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQL-LNELSLVE---AELLLKSSSLAGSYTTSLCLCIVAVLRRYHSCLILNPDQTAQVFDGLRIVVKSGVNPADCSSAERCILAYLYDLYTSCSHLKSKFGEIFSEFCSKVKNSIYWNIDPSDSNMLWDQVFMIDAIANPSAHNLNHSMVGKILNDSPAN-----RYSFVCNVLMDV--CVDHRDPERVNDIGILCAELTAYCRSLSAEWLGVLKALCCSSNNG------NCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---VRCVAIPSLLNAACSEQDS------EPGARLTCRILLHLFRTPQRNPCPQDGKSDKSTVGIRSSCDRHLLAASQNSIVVGAVFAVLKAVFMLGDAELKGSGFSHPAGLDDIGEDDMGSKKSGGRNVSIETASLDVYAKY------VLKSICQQEWVGERCLKSLSEDSSALQDPVLV-----NIQAQRLLQLICYPHRQL-DSEEGDNPQRQRIKRILQNMDQWTMRQSSLELQLMIKQSSNNELYSLLENIAKATIEVFQKSAE 1375 HSP 2 Score: 124.405 bits (311), Expect = 8.637e-28 Identity = 81/222 (36.49%), Postives = 121/222 (54.50%), Query Frame = 2
Query: 4337 DDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLF----------SIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
DD + K ++H ++K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ S+ + + ++KKLRKE+ D+ + E +E ++ LLP K T DVI P ++ ++ EK G Q V K++I+PW+V EG+K+ LS WF V D V EE L++ H H RP +YY
Sbjct: 1443 DDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTNEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQS-ESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFEKEGLQ---VSTKQKISPWDVFEGLKHSAPLSWGWFGTVRVDRKVTRFEEQQRLLLYHTHVKP--RPRSYY 1656
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Cavefish
Match: med12 (mediator complex subunit 12 [Source:NCBI gene;Acc:566632]) HSP 1 Score: 340.117 bits (871), Expect = 8.403e-94 Identity = 398/1454 (27.37%), Postives = 636/1454 (43.74%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVS-AMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRNTIDH-----------EYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVN-------LLLTNNKHPDRSI--------------------------TDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQE--NNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVV----ELLDRYDYNCYKDSSVFEGLCTVVVSLV---DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPIIDSQISADSE--PFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP---------------------------PIGGFLSVAHNXXXXXHRK--SPELDRMSTGD-NPDSVRSECSGLNQ-----ILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGY----------------------MFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRS--CPTFVMNMKKLEN-VFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIV---ETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQN----STANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSD-----KGRLQDQDYFDLTENNQVSFGPPFRR-SIDTEESFIHMKIWNFTLRVLREICCVSWV--RIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAE 3928
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F + +++ ++I + N DT KRK V KD + +S+ I W L+ T P +L K++P F KKE+V + KY VP+ R+ W IK++ A HA I K K R +D +W + L E+L + + R + E E + ++EY +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + +N L L+ HP SI TDFY C HR V+F LS ++ S+ L CP A+V++ N GSPLDLLP A S LP P G N R + ++E+ I +R AVE +W SF+ E TA I V E+LD + + S+ + L + D H + ++ LLCEW+V R+G HR +VA++++ I + +S Q+ L++FLDT++P++ ++ +SE F NLV LF ELI ++FS N YM +I+RG S ++LP P + + + HNSS++ + SP + + G +P+ E G + + P+ P V Y RH+QY HFPIP + HE N R LY + RD + ++++ KDI K+ ++ +F E+ +K+ R P AE I S+F+ L+++D V SQ + + ++ + LP I + +L+E S N S LI + LN + L+E + L+ + SL SY + +CI+ L ++ S L+ D ++F G+ ++ ++ V+ RC A + + SC+ L+S F K++N ++ NI P D+ ID + + +MV N + R+S V N L+ V C D R+N I + E + LS EW+ + +L N FN LL + +DL F+++++T +A ++ARQC D V CVA+ A +Q S P RL IL LF Q+N ++V D +LL++S + + +LK + + D G D+ E++ S R SI+T ++ K VL+ IC WV R S S ++D VL+ N QA+ LL +IC+P L + + R N++ W++ +++QL++ Q E ++EN++K I +F+ AE
Sbjct: 19 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSGDEHGSAKNVNFN------PSKISSNFSSIIAEKLRCNTFPDTGKRKPQVNQ--KDNFWL-VTARSQSSINIWFTDLAGTKPLTQLA-KKVPIFSKKEEVFGYLAKYSVPVMRSAWMIKMTCAYHAAI--TETKVKKRHVIDPCIEWTQIITKYLWEQLQKV-AEFYRQSPSQGCGSPLPATPAEVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPGEDELLKLLLPLLLQYSGE-FVQSAYLSRRLAYFCTRRLNLLLSDGSLGLSTGGHPPHSISGQPGNALPPTPTSQPAGGNQPQTPFTDFYI----CPQHRPVVFGLSCMLQSIVLCCPSALVWHYSLTDSRNKTGSPLDLLPIAPSNLPMPGGNSTFNQQVRAKVREIEEQIKERGQAVEFRW---SFDKCQETTAGFTIGRVLHTLEVLDNHSFEKSDFSNSLDSLYNRIFGSGQSKDGHEMSPDDDAVVTLLCEWAVCCKRSGRHRAMVVAKLLEKRQTEIEAERCGESEVVDEKGSVSSGSLSAATVPVFQDVLLQFLDTQAPVL-TEPGNESERVEFSNLVLLFCELIRHDVFSHNIYMCTLISRGDLASDSHLPRPRSPSDEPSDESERKEQDTGSSVKMEDTGLSEPMEIEHNSSANFDEQMFSPPMHGEAKGSPSPEKAAPEQDGKSTAKEKCMDPAFPQV-YEQ-PRHIQYATHFPIPQEESASHECNQRQVVLYGVGKQRDEARHAIKKITKDILKVLNRKSTAETGTEPQNEIVSNMNVCFTLSLFLSQGGEEGQKRKRSKPEAFPT-----AEDIFSKFQHLSHFDQHQVTSQVSRNVLEQITSFAL-------GMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQL-LNELSLVE---AELLLKSSSLAGSYTTSLCLCIVAVLRRYHSCLILNPDQTAQVFDGLRIVVKSGVNPADCSSAERCILAYLYDLYTSCSHLKSKFGEIFSEFCSKVKNSIYWNIDPSDSNMLWDQVFMIDAIANPSAHNLNHSMVGKILNDSPAN-----RYSFVCNVLMDV--CVDHRDPERVNDIGILCAELTAYCRSLSAEWLGVLKALCCSSNNG------NCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDL---VRCVAIPSLLNAACSEQDS------EPGARLTCRILLHLFRTPQRNPCPQDDKSTVGIRSSCDRHLLAASQNSIVVGAVFAVLKAVFMLGDAELKGSGFSHPAGLDDIGEDDMGSKKSGGRNVSIETASLDVYAKY------VLKSICQQEWVGERCLKSLSEDSSALQDPVLV-----NIQAQRLLQLICYPHRQL-DSEEGDNPQRQRIKRILQNMDQWTMRQSSLELQLMIKQSSNNELYSLLENIAKATIEVFQKSAE 1397 HSP 2 Score: 124.79 bits (312), Expect = 7.906e-28 Identity = 81/222 (36.49%), Postives = 121/222 (54.50%), Query Frame = 2
Query: 4337 DDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLF----------SIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
DD + K ++H ++K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ S+ + + ++KKLRKE+ D+ + E +E ++ LLP K T DVI P ++ ++ EK G Q V K++I+PW+V EG+K+ LS WF V D V EE L++ H H RP +YY
Sbjct: 1447 DDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTNEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQS-ESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFEKEGLQ---VSTKQKISPWDVFEGLKHSAPLSWGWFGTVRVDRKVTRFEEQQRLLLYHTHVKP--RPRSYY 1660
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002656.1 (pep scaffold:Pmarinus_7.0:GL481230:51:37267:1 gene:ENSPMAG00000002411.1 transcript:ENSPMAT00000002656.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 152.91 bits (385), Expect = 1.460e-37 Identity = 116/449 (25.84%), Postives = 220/449 (49.00%), Query Frame = 2
Query: 3677 SNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNY----QDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFS------IPNH-----GIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
SN QA++LL +IC+P L + + R +L+ W+L +++QL++ Q E +++EN++K I +F+ AE ++++ + + R E +P +NK + +++ ++E ++K + + + +S +L+ PF+SL++ CL +D+ R L SL +Q+ + N +E E+ DD++ + ++H +++ RL LVG +FD +Q S + +W +LL +++ G V++ +++ ELF TVLDMI L + + +P++ G+ + +KE+ DK + E ++ ++ LLP K T D+I P+ ++ ++ + KQG V K++++PW++ EG KN LS WF A + EE L++ H H RP YY
Sbjct: 12 SNKQAQHLLQLICYPHG-LPDAQDSDNPQRQRIKRILQHLDQWTLRQSWLELQLMIKQCHNSEMNNLLENIAKVTIEVFQQSAESNVSKKDTFTKLPSTRPKKFVLQSTGRG--GEWCASPRVITLPGTVNKSVGKSEEKET------RMEEWGGAGSNKEWDVCVSARARCVRRSMSLLSQQPFLSLVLTCLKGQDEQRESLLTSLQNQVNQIVSNWQE-ERYQDDMKARQMMHEALQLRLNLVGGMFDTVQRSSQCTTEWAVLLLQIVSTGTVDVQTNN-ELFTTVLDMIGVLRMSSCAADMPRLVPHYQAWPEGLYLSMLCYSRQKELGDKRS-ESIDKLRQ-LLPLPKQTVDIITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDMFEGQKNPAPLSWAWFGAARVERRAPRYEEQHRLLLYHTHAHP--RPLAYY 445
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002660.1 (pep scaffold:Pmarinus_7.0:GL481230:54:36427:1 gene:ENSPMAG00000002411.1 transcript:ENSPMAT00000002660.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 148.288 bits (373), Expect = 3.352e-36 Identity = 121/461 (26.25%), Postives = 221/461 (47.94%), Query Frame = 2
Query: 3677 SNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPE-------EERKDVIENVSKDIINLFKNQAE--QQANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLP---FDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNH-------GIKFFQMI--------KKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
SN QA++LL +IC+P L + + R +L+ W+L +++QL++ Q +E +++EN++K I +F+ AE +N L + S + + +L + LP + KR+ + E +G + + + +S +L+ PF+SL++ CL +D+ R L SL +Q+ + N +E E+ DD++ + ++H +++ RL LVG +FD +Q S + +W +LL +++ G V++ +++ ELF TVLDMI L+ L +IP + G+ + + + + +KE+ DK + E ++ ++ LLP K T D+I P+ ++ ++ + KQG V K++++PW++ EG KN LS WF A + EE L++ H H RP YY
Sbjct: 11 SNKQAQHLLQLICYPHG-LPDAQDSDNPQRQRIKRILQHLDQWTLRQSWLELQLMIKQCHNSVSSQRVQEMNNLLENIAKVTIEVFQQSAEMNSSSNLMSLGLLGHGGGGPGTGVGSSDAAQNAAAAAKKKPFLSSPRVITLPGGVWGKAKRKKHTSMEEWGGAGSNKEWDVCVSARARCVRRSMSLLSQQPFLSLVLTCLKGQDEQRESLLTSLQNQVNQIVSNWQE-ERYQDDMKARQMMHEALQLRLNLVGGMFDTVQRSSQCTTEWAVLLLQIVSTGTVDVQTNN-ELFTTVLDMIGVLLKNLKTIPKYLPFVQRGGVHYSRHMYSRSTGIDAEKKKELGDKRS-ESIDKLRQ-LLPLPKQTVDIITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDMFEGQKNPAPLSWAWFGAARVERRAPRYEEQHRLLLYHTHAHP--RPLAYY 464
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002662.1 (pep scaffold:Pmarinus_7.0:GL481230:54:36427:1 gene:ENSPMAG00000002411.1 transcript:ENSPMAT00000002662.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 146.747 bits (369), Expect = 4.861e-36 Identity = 120/461 (26.03%), Postives = 221/461 (47.94%), Query Frame = 2
Query: 3677 SNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPE-------EERKDVIENVSKDIINLFKNQAE--QQANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLP---FDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNH-------GIKFFQMI--------KKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEK-SGKQGCAVQRKERINPWEVIEGIKN--LFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
SN QA++LL +IC+P L + + R +L+ W+L +++QL++ Q +E +++EN++K I +F+ AE +N L + S + + +L + LP + KR+ + E +G + + + +S +L+ PF+SL++ CL +D+ R L SL +Q+ + N +E E+ DD++ + ++H +++ RL LVG +FD +Q S + +W +LL +++ G V++ +++ ELF TVLDMI L+ L +IP + G+ + + + + +KE+ DK + E ++ ++ LLP K T D+I P+ ++ ++ + KQG V K++++PW++ EG KN S +WF A + EE L++ H H RP YY
Sbjct: 11 SNKQAQHLLQLICYPHG-LPDAQDSDNPQRQRIKRILQHLDQWTLRQSWLELQLMIKQCHNSVSSQRVQEMNNLLENIAKVTIEVFQQSAEMNSSSNLMSLGLLGHGGGGPGTGVGSSDAAQNAAAAAKKKPFLSSPRVITLPGGVWGKAKRKKHTSMEEWGGAGSNKEWDVCVSARARCVRRSMSLLSQQPFLSLVLTCLKGQDEQRESLLTSLQNQVNQIVSNWQE-ERYQDDMKARQMMHEALQLRLNLVGGMFDTVQRSSQCTTEWAVLLLQIVSTGTVDVQTNN-ELFTTVLDMIGVLLKNLKTIPKYLPFVQRGGVHYSRHMYSRSTGIDAEKKKELGDKRS-ESIDKLRQ-LLPLPKQTVDIITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDMFEGQKNPAPLSWAWFGAARVERRAPRYEEQHRLLLYHTHAHP--RPLAYY 464
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Nematostella
Match: EDO45183 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTC1]) HSP 1 Score: 86.2705 bits (212), Expect = 1.456e-16 Identity = 63/227 (27.75%), Postives = 107/227 (47.14%), Query Frame = 2
Query: 4325 EKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHS--DHSELFYTVLDMISTLIHTL-----FSIP---NHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFK-NTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKN--LFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
E+ P DL+ K ++ ++ R++LVG +FD IQ S L DW +L +L+ G + S EL VLDM+ LI + S P + KKL++E+ K + ++ + LP N Y V + T+ ++ QG + K++I+ WE++EG KN F+ +WF AV + L E+ ++ H+H + +P +Y+
Sbjct: 1117 ERCPADLKSKEVLQEALHLRISLVGAMFDTIQRSVALSSDWASVLFQLVSSGTITTESLPSKKELLTNVLDMVCVLISVVTNTDGLSGPAAEESRKAAGALFKKLKRELAGKSPMDIIQCKQLLPLPSLSHNVYTV------------EPSTETSPAQTDMQGLQINGKQKISAWELMEGQKNPSPFAWAWFGAVRIERKPLRYEQEFRKLMHHNHARR--KPASYF 1329 HSP 2 Score: 61.2326 bits (147), Expect = 5.035e-9 Identity = 54/214 (25.23%), Postives = 92/214 (42.99%), Query Frame = 2
Query: 3302 MEQQNSTANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGR----------------------LQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDII---------DTMNRTFTNLNIWSLHFDQMKIQLLLTQ 3850
M +S+A+ S D NLL+++ + + + ++ +LK + S+ GR + D+ D + + F PP S E+ FTL+V IC WVR R + +L +L+D ++ SQAR LL++IC+P TS I+ + +R NL+ WSL +++QL++ Q
Sbjct: 34 MSHDHSSASKYSFKSSPDHNLLAAAHEHIVVDAVLAVLKAMLKLSEAGRNNGLGSHGTESSRDDGFRTWFSAKLDDFMDSSGSTGDIFPPPLASSRSAMETSNTSAFAGFTLQV---ICSQEWVRERCLHDL-EKLCSPELLLDPALTVSQARKLLHLICYPAGV--PTSLGGPSILPGGETETVKEAASRILQNLDQWSLRKSWLELQLMIKQ 241
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Nematostella
Match: EDO45182 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTB9]) HSP 1 Score: 85.1149 bits (209), Expect = 2.397e-16 Identity = 82/347 (23.63%), Postives = 143/347 (41.21%), Query Frame = 2
Query: 1022 EYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNI---------------KIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKL---EQFILQRSLAVENQWKHESFECSIEQTAAGLIKV------VELLDRYDY------NC--------YKDSS----------VFEGLCTVVVSLVD-------------NHSL------------LLMLLCEWSVSTMRTGTHRPFLVAQIIDNIHQN-----------------QSHQSI-----QNCLVEFLDTKSPIIDSQISADSEP-FRNLVCLFGELIERELFSMNDYMSYMIARGLFE--SVANLPLPP 1768
+Y +CS H +++ L +I ++++ CP A+V+N+ + L L + G N +N++ + L E+ + R LAVE++W + ++ +I V +E+LD+YD+ NC + +S VF L + L++ N SL + +LLCEW++S R G HR F+VA+++ + H I Q L+EFLD +P+++S + +P F LV LF EL+ ++FS N Y+ +I+RG + ++P PP
Sbjct: 80 QYKNCSQHNSLVLALGAIIQAVTICCPGALVWNSTVCSSGQSSSSNNSGDQTKPQVLGSPLDRLPMAPSALPMPGGGNNNPINQEVMLSLLASEESVKTRGLAVESRWSPDKYQDKTSAVCFSVIAVNRVLTTLEILDKYDFTRADNTNCIDLLYAKIFTSASKGNREVNITCVFWYLKLLPPHLINMLESSSSVSSSNINFSLRITSWLTSTDEAIALLLCEWAISKHRVGKHRAFVVAKLLQRRQSDLLNKKDDSTSGGEESNSSRHNPIATPVCQKVLLEFLDNYAPVVESYQHSKGDPSFAQLVLLFVELVRHDVFSHNAYLCTLISRGDLQPTPAVSIPSPP 426
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Nematostella
Match: EDO25821 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DVD8]) HSP 1 Score: 50.0618 bits (118), Expect = 1.848e-6 Identity = 40/164 (24.39%), Postives = 73/164 (44.51%), Query Frame = 2
Query: 4508 ELFYTVLDMISTLIHTLFSIPNHGIKFFQ--------MIKKLRKEICDKLNYEGVELIKPFLLPCFK-NTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKN--LFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
EL VLDM+ LI + + + + KKL++E+ K + ++ + LP N Y V + T+ ++ QG + K++I+ WE++EG KN F+ +WF AV + L E+ ++ H+H + +P +Y+
Sbjct: 1 ELLTNVLDMVCVLISVVTNTDGLSGPAAEESRKAAGALFKKLKRELAGKSPMDIIQCKQLLPLPSLSHNVYTVEPSTE------------TSPAQTDMQGLQINGKQKISAWELMEGQKNPSPFAWAWFGAVRIERKPLRYEQEFRKLMHHNHARR--KPASYF 150
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Medaka
Match: med12 (mediator complex subunit 12 [Source:NCBI gene;Acc:101155359]) HSP 1 Score: 479.559 bits (1233), Expect = 6.577e-138 Identity = 495/1787 (27.70%), Postives = 818/1787 (45.78%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVS-AMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRN-----------TIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQC--SDDEQMMKFYLPFLLYFGDRFKESEILTRKLLHGLCNSVNLLLTNNK-------HPDRSI--------------------------TDFYAEYSSCSTHRTVMFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKL---EQFILQRSLAVENQWKHESFECSIEQTAAGLI-KVVELLDRYDYNCYKDSSVFEGLCTVVVSLV------DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPIIDSQISADSE--PFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLP------------------------PIGGFLSVAHNXXXXXHRK-SPELDRMSTG------DNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRSCPTFVMN--MKKLEN-VFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIV---ETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNSTANSVSAFKKE--------DVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWV--RIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLF----------SIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ ++I + N DT KRK V KD + +S+ I W L T P +L K++P F KKE+V + KY VP+ R+ W IK++ A HA I K K R +D +W + L E+L + + R + E + ++EY +L + M+ + +LD E L W++ E+ +DE + L Y G+ F +S L+R+L + +NLLL++ HP SI TDFY C HR ++F LS ++ S+ L CP A+V++ N GSPLDLLP A S+LP P G + AKL E+ I +R AVE +W SF+ E TA I +V+ L+ D + ++ S L ++ + D H + ++ LLCEW+V R+G HR +VA++++ I + +S Q+ L++FLDT++P + ++ +SE F NLV LF ELI ++FS N YM +I+RG S ++LP P + + + HNSS++ SP + S G + PD + P+ P + RH+QY HFPIP + HE N R LY + RD + ++++ KDI K+ ++ + + RK+S+ + AE + S+F+ L+++D V SQ + +N ++ + LP I + +L+E S N S LI + LN + L+E + L+ + SL+ SY + +CI+ L ++ + L+ + ++F G+ ++ + V+ RC A + + SC+ L++ +++ K++N ++ NI P D ++ + + F ++V N + R+S VVN L+ V C D R+N I + E + LS EW+ + +L N FN LL + +DL +++++T +A ++ARQC D V CVA+ A +Q S P RL IL LF Q+N + K D +LL++S + + +LK + + D L+ + +S RR++ E + + + + VL+ IC WV R S S ++D VL N QA+ LL +IC+P L + + + R N++ W++ +++QL++ Q E ++EN++K I +F+ AE ++ + +S + + KP S E + +L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + K ++H ++K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ S+ + + ++KKLRKE+ D+ + E +E ++ LLP K T DVI P ++ ++ EK G Q V K++I+PW+V EG+K+ LS WF D EE ++ H H +P +YY
Sbjct: 20 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSSDEHGSAKNVNFN------PAKISSNFSSIIAEKLRFNSFPDTGKRKPQVNQ--KDNFWL-VTARSQSSINSWFTDLGGTKPLTQLA-KKVPIFSKKEEVFAYLAKYSVPVMRSAWMIKMTCAYHAAI--TETKVKKRHVIDPCIEWTQIITKYLWEQLQKV-AEFYRQCPSQGCSSPPPATPADVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKVRPGEDELLRLLLPLLLQYSGE-FVQSAYLSRRLAYFCTRRLNLLLSDRSLVPGTVGHPGHSILTQQGNALPSTPTSQPAGGNQPQTPFTDFYI----CQQHRPLVFGLSCMLQSIVLCCPSALVWHYSLTDSRNKTGSPLDLLPFAPSSLPMP-GCNTAFTQQVRAKLREIEEQIKERGQAVEFRW---SFDKCQETTAGFTIGRVLHTLEVLDNHSFEKSDFNNSLDSLYNRIFGSGQSKDGHEMSPDDDAVVTLLCEWAVCCKRSGRHRAMVVAKLLEKRQAEIEAERCAESEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPTL-TEPGNESERVEFSNLVLLFCELIRHDVFSHNIYMCTLISRGDLASESHLPRPRSPSDDESERKEQDAGSSVKMEDTGLSESMEIEHNSSANFDEMFSPPMHCESKGSPSPEKNAPDQDSKANCKDKSMDPAFP--QLYDQPRHIQYATHFPIPQEESASHECNQRLVVLYGVGKLRDEARHTIKKITKDILKVLNRKSTAETGGEEGQKRKRSKPE-------AFPTAEDLFSKFQHLSHFDQHQVTSQVSRNVLEQINSFAL-------GMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQL-LNELSLVE---AELLLKSSSLVGSYTTSLCLCIVAVLRRYHTCLILNPEQTAQVFDGLQIVVKLVVNPADCSSAERCILAYLYDLYTSCSHLKNKFGEIISELCSKVKNSIYCNIDPSDSNMLWDPGFMLEAIANPSAHNFNHSVVGKILNDSPAN-----RYSFVVNVLMDV--CMDHRDPERVNDIGILCAELTAYCRSLSAEWLGILKALCCSSNNG------NCGFNDLLCNVDVSDLSLHDSLATFVAILIARQCLLLEDL---VRCVAIPSLLNAACSEQDS------EPGARLTCRILLHLFKTPQRNPVPQDGAKSDKSMVGIRSSCDRHLLAASQNSIVVGAVFAVLKAVFMLGD-AELRGSGLSHPAGLDDISD----RRNVSIETASLDV----YAKYVLKTICQQEWVGERCLKSLSEDSSALQDPVL-----GNIQAQRLLQLICYPHRQL-DSDEGENPQLQRIKRILQNMDQWTMRQSCLELQLMIKQSSNNELYSLLENIAKATIEVFQKSAEMNSSNPSGNGTAAHGGSASNSNSTTSKIKPILSSSERSGVWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWRE-DQYQDDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQS-ESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFEKEGLQ---VSTKQKISPWDVFEGLKHSAPLSWGWFGTTRVDRKTTKFEEQHRFLLYHTHMKP--KPRSYY 1714
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Medaka
Match: med12 (mediator complex subunit 12 [Source:NCBI gene;Acc:101155359]) HSP 1 Score: 353.599 bits (906), Expect = 2.122e-98 Identity = 360/1351 (26.65%), Postives = 616/1351 (45.60%), Query Frame = 2
Query: 1226 RDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLI-KVVELLDRYDYNCYKDSSVFEGLCTVVVSLV------DNHSL------LLMLLCEWSVSTMRTGTHRPFLVAQIIDN----IHQNQSHQS---------------------IQNCLVEFLDTKSPIIDSQISADSE--PFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRKSPELDRMSTGDNPDS------VRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVN--GYVNRCSAAVVIQQFQSCATLRSCPTFVMN--MKKLEN-VFRNIKPDK-----DRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIV---ETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVS---NDLLFYENISTLIATMLARQCFYFSDFLGRVICVAL-----AQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNSTANSVSAFKKE--------DVNLLSSSLQKVTTELLVDLLKM-------LAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWV--RIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTS------KDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPT-ESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCL-AKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGI----------KFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLS--WFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYY 4966
R + ++E+ I +R AVE +W SF+ E TA I +V+ L+ D + ++ S L ++ + D H + ++ LLCEW+V R+G HR +VA++++ I + +S Q+ L++FLDT++P + ++ +SE F NLV LF ELI ++FS N YM +I+RG S ++LP P S + + S + + +M +P+ ++ C + P+ P + RH+QY HFPIP + HE N R LY + RD + ++++ KDI K+ ++ + E+ +K+ R P AE + S+F+ L+++D V SQ + +N ++ + LP I + +L+E S N S LI + LN + L+E + L+ + SL+ SY + +CI+ L ++ + L+ + ++F G+ ++ + V+ RC A + + SC+ L++ +++ K++N ++ NI P D ++ + + F ++V N + R+S VVN L+ V C D R+N I + E + LS EW+ + +L N FN LL + +DL +++++T +A ++ARQC D V CVA+ A +Q S P RL IL LF Q+N + K D +LL++S + + +LK L++H L+ + +S RR++ E + + + + VL+ IC WV R S S ++D VL N QA+ LL +IC+P L + K I+ R N W + F ++++QLL E ++EN++K I +F+ AE ++ + +S + + KP S E + +L+ LI KLP + + ++ AA E+LE G+H + + ++++ KS +L+ PF+SL++ CL +D+ R L SL Q++ + N +E ++ DD + K ++H ++K RL LVG +FD +Q S + +W +LL +I G V+M S++ ELF TVLDM+S LI+ + I + ++KKLRKE+ D+ E +E ++ LLP K T DVI P ++ ++ EK G Q V K++I+PW+V EG+K+ LS WF D EE ++ H H +P +YY
Sbjct: 283 RAKLREIEEQIKERGQAVEFRW---SFDKCQETTAGFTIGRVLHTLEVLDNHSFEKSDFNNSLDSLYNRIFGSGQSKDGHEMSPDDDAVVTLLCEWAVCCKRSGRHRAMVVAKLLEKRQAEIEAERCAESEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPTL-TEPGNESERVEFSNLVLLFCELIRHDVFSHNIYMCTLISRGDLASESHLPRP-----RSPSDDESERKEQDAGSSVKMEGSPSPEKNAPDQDSKANCKD-KSMDPAFP--QLYDQPRHIQYATHFPIPQEESASHECNQRLVVLYGVGKLRDEARHTIKKITKDILKVLNRKSTA-ETGDGEEGQKRKRSKPEAFPT-----AEDLFSKFQHLSHFDQHQVTSQVSRNVLEQINSFAL-------GMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQL-LNELSLVE---AELLLKSSSLVGSYTTSLCLCIVAVLRRYHTCLILNPEQTAQVFDGLQIVVKLVVNPADCSSAERCILAYLYDLYTSCSHLKNKFGEIISELCSKVKNSIYCNIDPSDSNMLWDPGFMLEAIANPSAHNFNHSVVGKILNDSPAN-----RYSFVVNVLMDV--CMDHRDPERVNDIGILCAELTAYCRSLSAEWLGILKALCCSSNNGNC------GFNDLLCNVDVSDLSLHDSLATFVAILIARQCLLLEDL---VRCVAIPSLLNAACSEQDS------EPGARLTCRILLHLFKTPQRNPVPQDGAKSDKSMVGIRSSCDRHLLAASQNSIVVGAVFAVLKAVFMLGMNLSLHRQTRTLRGSGLSHPAGLDDISD----RRNVSIETASLDV----YAKYVLKTICQQEWVGERCLKSLSEDSSALQDPVL-----GNIQAQRLLQLICYPHRQLDSDEGENPQLQRIKRILQVQERGVFQPNGW-IGFIKLQLQLLRFVSGASELYSLLENIAKATIEVFQKSAEMNSSNPSGNGTAAHGGSASNSNSTTSKIKPILSSSERSGVWLVAPLIAKLP-TSVQGHVLKAAGEELEKGQHLGS-SSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWRE-DQYQDDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNN-ELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDR-QSESLEKVRQ-LLPLPKQTRDVITCEPQGSLIDTKGNKIAGFEKEGLQ---VSTKQKISPWDVFEGLKHSAPLSWGWFGTTRVDRKTTKFEEQHRFLLYHTHMKP--KPRSYY 1557 HSP 2 Score: 113.235 bits (282), Expect = 1.991e-24 Identity = 85/264 (32.20%), Postives = 129/264 (48.86%), Query Frame = 2
Query: 110 LGPPDVYQQEYKQKEDLLTEFNVREGFNYSKPVV--EEHESAKDIGFEFISKPFLTDLNNFMQAVIVKSHNNNIKQDTTKRKVTVATLFKDLQCIPAIEKSKEIIYDWMIQLSDTIPYAELINKRIPYFHKKEDVLKEIFKYQVPITRAIWFIKVS-AMHATIQAESNKKKPRSNVDSLSDWVLSFIRTLNEKLDLIRIKLMRN-----------TIDHEYEMTVSEFEYLMRLMVAMYDEDLLDHTEVLQWLVSTNEQCSDDE 859
LGPPDVY Q+ KQKED LT NV++GFN ++P V +EH SAK++ F +++ ++I + N DT KRK V KD + +S+ I W L T P +L K++P F KKE+V + KY VP+ R+ W IK++ A HA I K K R +D +W + L E+L + + R + E + ++EY +L + M+ + +LD E L W++ E+ E
Sbjct: 19 LGPPDVYPQDPKQKEDELTALNVKQGFN-NQPAVSSDEHGSAKNVNFN------PAKISSNFSSIIAEKLRFNSFPDTGKRKPQVNQ--KDNFWL-VTARSQSSINSWFTDLGGTKPLTQLA-KKVPIFSKKEEVFAYLAKYSVPVMRSAWMIKMTCAYHAAIT--ETKVKKRHVIDPCIEWTQIITKYLWEQLQKV-AEFYRQCPSQGCSSPPPATPADVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKVRPGE 268
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Planmine SMEST
Match: SMESG000000954.1 (SMESG000000954.1) HSP 1 Score: 3125.88 bits (8103), Expect = 0.000e+0 Identity = 1640/1641 (99.94%), Postives = 1640/1641 (99.94%), Query Frame = 2
Query: 1055 MFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGXXXXXXXXXXXXXXXXXGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVVELLDRYDYNCYKDSSVFEGLCTVVVSLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDNIHQNQSHQSIQNCLVEFLDTKSPIIDSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNXXXXXHRKSPELDRMSTGDNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVNGYVNRCSAAVVIQQFQSCATLRSCPTFVMNMKKLENVFRNIKPDKDRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVSNDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNSTANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVXXXXXXXXXXXXHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCLAKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYYTSFPEILPEDIKDPSISDPMEIINSSGPPSVQXXXXXXXXXXXXXXXXXXXXXMENPRDNNPGSVKINQENPSMPPLTRPRSNASSGIGPTKRKKPKRSNNQSNSGQSIMANQISNHHPMSRNVPSPAILPGNPNLMMRHHPPGMSMVPPNGNIGLAIAAHRYPNHGIDYSGYGSHQIGSGFSELPSNAYLQSQHYSQSVYDSNQRANQMSCTRPNRTSRSNINQTLKSKIQQRQPSQDHPMLSSFHGNTXXXXXXXXXXXXXXXXXXXXXXXXLEDIXXXXXXXXXXXXXXTLMNNYQLTRTYSDSSXXXXXXXXXXXXXXXSRLHPSQYNRYGQF 5977
MFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGSPLDLLPCALSALPCPPGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVVELLDRYDYNCYKDSSVFEGLCTVVVSLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDNIHQNQSHQSIQNCLVEFLDTKSPIIDSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNSSSSSHRKSPELDRMSTGDNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVNGYVNRCSAAVVIQQFQSCATLRSCPTFVMNMKKLENVFRNIKPDKDRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVSNDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNSTANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVDDDYNDDRYDQYHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCLAKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYYTSFPEILPEDIKDPSISDPMEIINSSGPPSVQNGINNSNNNTSNHINNINSNSMENPRDNNPGSVKINQENPSMPPLTRPRSNASSGIGPTKRKKPKRSNNQSNSGQSIMANQISNHHPMSRNV SPAILPGNPNLMMRHHPPGMSMVPPNGNIGLAIAAHRYPNHGIDYSGYGSHQIGSGFSELPSNAYLQSQHYSQSVYDSNQRANQMSCTRPNRTSRSNINQTLKSKIQQRQPSQDHPMLSSFHGNTQQQQQQSILPPPPPYHNNSSSNIPLEDINNVAPVPPPNYNNPTLMNNYQLTRTYSDSSMQQYMQQQQQQQQQQSRLHPSQYNRYGQF
Sbjct: 1 MFCLSGLIVSLSLECPCAVVYNNIKIPGHNLNGSPLDLLPCALSALPCPPGQENNLNRDTIAKLEQFILQRSLAVENQWKHESFECSIEQTAAGLIKVVELLDRYDYNCYKDSSVFEGLCTVVVSLVDNHSLLLMLLCEWSVSTMRTGTHRPFLVAQIIDNIHQNQSHQSIQNCLVEFLDTKSPIIDSQISADSEPFRNLVCLFGELIERELFSMNDYMSYMIARGLFESVANLPLPPIGGFLSVAHNSSSSSHRKSPELDRMSTGDNPDSVRSECSGLNQILPSIPIVDYRNFNRHLQYLIHFPIPVNDDYVHEHNLRSQKLYCTSRTRDANKQFLRRLAKDIGKMYTKRGYMFDIIQIEKSRKKSRRDPREESMLIEKLAESIQSRFKCLTYYDMECVLSQCLPTCVNSLNIHSILANKLQSTSNMFLPYPTIISTLLNLIEQSCNYSLLIRIIDECSLNLVKLIEHLSRQGLITNYSLIYSYMSRFRICIIGFLFKFQSVLMTMSDCRCRIFHGIFVLSRNFVSVNGYVNRCSAAVVIQQFQSCATLRSCPTFVMNMKKLENVFRNIKPDKDRSSSIDYVESVGMDLFKINMVSCSENVTELQLNVNLRFSLVVNCLLHVVQCTDVDQLARINTIIVETVSNASMLSTEWITAIYSLLLPGNASPGYEQFVNKFNSLLVSNDLLFYENISTLIATMLARQCFYFSDFLGRVICVALAQGIDQQSIVCPPIVPTTRLASYILFRLFTMEQQNSTANSVSAFKKEDVNLLSSSLQKVTTELLVDLLKMLAVHSDKGRLQDQDYFDLTENNQVSFGPPFRRSIDTEESFIHMKIWNFTLRVLREICCVSWVRIRFSQETPSRLIRDNVLIDKNISNSQARNLLNIICHPKDHLWQTSCTSKDIIDTMNRTFTNLNIWSLHFDQMKIQLLLTQIPEEERKDVIENVSKDIINLFKNQAEQQANQRELVDDDYNDDRYDQYHSQSHRQKPTESIEINSAYLIPSLINKLPFDNFKRQLIAAASEKLESGKHFCTHKNYQDKENDLTKSSLILTYPPFISLLIVCLAKDDNRSEFLKSLADQIEYYIDNAKETEKMPDDLRVKHLIHTSMKSRLALVGYLFDRIQESWELIGDWCLLLSKLIIYGVVEMHSDHSELFYTVLDMISTLIHTLFSIPNHGIKFFQMIKKLRKEICDKLNYEGVELIKPFLLPCFKNTYDVIVTVPLRMPHKSQQYRLTTAEKSGKQGCAVQRKERINPWEVIEGIKNLFSLSWFAAVSCDTPVLPIEEHANLMIGHDHPDKLIRPDNYYTSFPEILPEDIKDPSISDPMEIINSSGPPSVQNGINNSNNNTSNHINNINSNSMENPRDNNPGSVKINQENPSMPPLTRPRSNASSGIGPTKRKKPKRSNNQSNSGQSIMANQISNHHPMSRNVLSPAILPGNPNLMMRHHPPGMSMVPPNGNIGLAIAAHRYPNHGIDYSGYGSHQIGSGFSELPSNAYLQSQHYSQSVYDSNQRANQMSCTRPNRTSRSNINQTLKSKIQQRQPSQDHPMLSSFHGNTQQQQQQSILPPPPPYHNNSSSNIPLEDINNVAPVPPPNYNNPTLMNNYQLTRTYSDSSMQQYMQQQQQQQQQQSRLHPSQYNRYGQF 1641 The following BLAST results are available for this feature:
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of Mediator of RNA polymerase II transcription subunit 12-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021839 ID=SMED30021839|Name=Mediator of RNA polymerase II transcription subunit 12-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=6029bpback to top protein sequence of SMED30021839-orf-1 >SMED30021839-orf-1 ID=SMED30021839-orf-1|Name=SMED30021839-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1984bp MSYYHSLETHPLKCLKQTEGYNSHKVLLGPPDVYQQEYKQKEDLLTEFNVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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