Cytochrome P450 2K1-like protein

Overview
NameCytochrome P450 2K1-like protein
Smed IDSMED30021752
Length (bp)1325
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cytochrome P450 2K1-like protein (SMED30021752) t-SNE clustered cells

Violin plots show distribution of expression levels for Cytochrome P450 2K1-like protein (SMED30021752) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cytochrome P450 2K1-like protein (SMED30021752) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cytochrome P450 2K1-like protein (SMED30021752) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30021752

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 20

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30021752h1SMcG0016629 PL08009B2D05ncbi_smed_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30021752h1SMcG0012519 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30021752h1SMcG0012519 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30021752h1SMcG0012519 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30021752h1SMcG0016629 PL08001B2F05ncbi_smed_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30021752h1SMcG0016629 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30021752h1SMcG0016629 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30021752h1SMcG0016629 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30021752h1SMcG0016631 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30021752h1SMcG0016631 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30021752h1SMcG0016631 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30021752h1SMcG0016632 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30021752h1SMcG0016632 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30021752h1SMcG0016632 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30021752h1SMcG0016633 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
epidermisSMED30021752h1SMcG0016633 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30021752h1SMcG0016633 Contig1511GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30021752h1SMcG0016632 PL08001B2F05ncbi_smed_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30021752h1SMcG0016629 SMED30021752smed_20140614PMID:26457503
Tu et al., 2015
whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30021752h1SMcG0016629 SMED30021752smed_20140614PMID:26457503
Tu et al., 2015
whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Match: CYP2J2 (cytochrome P450 family 2 subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:2634])

HSP 1 Score: 217.624 bits (553), Expect = 1.144e-64
Identity = 132/364 (36.26%), Postives = 197/364 (54.12%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDN---LAKNK-----DIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGN-VESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRF 1067
            +   G  W  QR F L  LR+FGLGK    E IQ E  +L + +   + Q  D         +NII      +RF   D   Q + K +D    L  +K     ++F  I+   P   Q+           S+WK   K++ + +  I +HR   +  +E  D +D +L    E+ + TGN   SF +  LI ++L+L  AG ETTSTTL W  L+M+ YP+IQEKV  EI  +IG+ + P+   ++++ YT AV+ EV R+ ++ P+ +      D  + G+++PK ++I  NL A H DP  W +P TF P+HFL    NG  +++ RE  +PFS+GKR CLGE LAR+E FIFF S++Q+F
Sbjct:  127 IMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLF---------SNWK---KLKLFVSHMIDKHRKDWN-PAETRDFIDAYL---KEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL---ENG--QFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Match: CYP2B6 (cytochrome P450 family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:2615])

HSP 1 Score: 211.075 bits (536), Expect = 2.237e-62
Identity = 126/362 (34.81%), Postives = 192/362 (53.04%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN----IQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            +F +G+ W + R F +  +RDFG+GK    E IQ E   L++EL      ++D +  F   T NII   +  KRF   D      +   ++T   ++    +F  +  +F    + F  A         +K   +I  Y    +++HR  LD  S  +DL+D +L+  H  K+ +     F    L  N+L L  AG ETTSTTL +  L M KYP + E+V++EI ++IG  R P ++D+  + YT+AV+ E+ R S + PMG+ H      +  G+ IPKD+ +F  L     DP  +E P  F P+HF  LD+NG  K    E  IPFS+GKR CLGE +AR+E F+FF +++Q F ++
Sbjct:  114 IFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLIS---SVFGQLFELFSGFLKYFPGAHR-----QVYKNLQEINAYIGHSVEKHRETLD-PSAPKDLIDTYLL--HMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHF--LDANGALKKT--EAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMA 460          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Match: CYP2U1 (cytochrome P450 family 2 subfamily U member 1 [Source:HGNC Symbol;Acc:HGNC:20582])

HSP 1 Score: 202.601 bits (514), Expect = 1.299e-58
Identity = 136/397 (34.26%), Postives = 198/397 (49.87%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFS-DQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVAR----LLFLFVSDWKRFVKIQ----DYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            G +W  QR F    LR FGLGK      I  E   +  E+     D    FS       +NII      +RF  D  N +F  K +  +++  +I         CL+   ++      L +L    +K   +I+     +  + IK+H+ +LD     +D +D +L+   E +++  N  SF +  L     +L IAG +TT+ +L WC L+MS  PD+QEKVH+EI  +IG  R P++ DK  + YT+A + EV RL+ V P+ + H T ++  + G+ IPK +LI PNL++ H DP IWE P  FYP  FL      I K    E  IPF +GKR C+GE LA+ E F+ FVS++Q    SF   + ED     + G  GL       N    RR
Sbjct:  171 GPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFS-IISNAVSNIICSLCFGQRF--DYTNSEFK-KMLGFMSRGLEI---------CLNSQVLLVNICPWLYYLPFGPFKELRQIEKDITSFLKKIIKDHQESLD-RENPQDFIDMYLLHMEEERKNNSN-SSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKK----ETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQ----SFAFALPEDSKKPLLTGRFGLTLAPHPFNITISRR 544          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Match: CYP2R1 (cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580])

HSP 1 Score: 196.052 bits (497), Expect = 1.203e-56
Identity = 125/372 (33.60%), Postives = 190/372 (51.08%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDN---LAKNKDIF------HLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISED 1100
            G  W   R   +   R FG G+      I  E     D ++T+  +  DF +      +NI +  I  +RFT +D + Q + +       LA +  +F       + +L F    Q F  A +++ F+S  +   K       ++ +H             +D +L    E+ Q   +  S F    LI +  ELIIAG ETT+  L W  LFM+ YP+IQ +V KEI  I+G    P+ +DK  + YT+AV+ EVLR  ++ P+G+ H T +DA + G+ IPK + +  NLY+ H D + W  P  F+PE F  LDS+G   +  +E L+PFS+G+R CLGE LAR E F+FF +++QRF + F  E+  D
Sbjct:  130 GRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPFGKHQQLFRNAAVVYDFLS--RLIEKASVNRKPQLPQH------------FVDAYL---DEMDQGKNDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERF--LDSSGY--FAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVPD 480          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Match: CYP2D6 (cytochrome P450 family 2 subfamily D member 6 [Source:HGNC Symbol;Acc:HGNC:2625])

HSP 1 Score: 195.282 bits (495), Expect = 2.322e-56
Identity = 126/368 (34.24%), Postives = 179/368 (48.64%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN-IQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQ 1112
            G  W  QR F +  LR+ GLGK    + +  E   L       S +    +       +N+I+     +RF  DDP  ++ +    + L +       +L   P L     +A  +  F    K F+   D   E + EHR   D      DL + FL    E++++ GN ES F D  L     +L  AG  TTSTTL W  L M  +PD+Q +V +EI ++IG+ R P M D+  + YT AV+ EV R   + P+G+ H T  D  + GF IPK + +  NL +   D  +WE P  F+PEHF  LD+ G   +   E  +PFS G+R CLGE LAR E F+FF S++Q F  SF     + R S 
Sbjct:  125 GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRF---QKAFLTQLD---ELLTEHRMTWDPAQPPRDLTEAFLA---EMEKAKGNPESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHF--LDAQG--HFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF--SFSVPTGQPRPSH 477          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Match: cyp-33C7 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:O16673])

HSP 1 Score: 191.43 bits (485), Expect = 2.848e-55
Identity = 120/364 (32.97%), Postives = 191/364 (52.47%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAK-NKDIF---HLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSE-GEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEE 1088
            +GH+W   R F L  LRDFGLGK    E I  E  ++  + D   D+ ++ S        N+I++ I   RF   D + Q  +K + +L +  +++F    + + +F       +    L   + DWK      D+F  +I+ HR  +DF SE  +D  + +L K+ +  ++ G+ E F + QL    L+L  AG  TT+TT NW   ++   P + EK+H E+ +++G +RL T  DK  L Y  AV++E  R +++ P+ L H T  D  ING+ + K + +   +    +D +++  P  F PE F  +D +G  K    +EL+PFS+GKRQC GE LAR E F+F  +   R+QIS   E
Sbjct:  114 NGHLWNTHRRFALSTLRDFGLGKDLMQEKILIEVEDIFRKYDAQIDKDMEISTILHNAIANVINQTIFGYRF---DESNQEEYKKLKHLIEFQENVFTSAKVTVQVFAPKLGKILPGESLEDLMKDWKN--SFYDFFNTQIENHRQKIDFDSEESQDYAEAYL-KEQKKYEALGDTELFSNKQLSNTCLDLWFAGLSTTNTTANWTICYVMNTPGVLEKIHDELDKVVGSDRLVTTADKNNLPYMNAVINESQRCTNIVPINLFHATTRDTVINGYPVKKGTGVIAQISTVMLDEKVFPEPYKFKPERF--IDESG--KLIKVDELVPFSIGKRQCPGEGLARMELFLFIANFFNRYQISPSSE 467          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Match: cyp-33C5 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:O16671])

HSP 1 Score: 186.808 bits (473), Expect = 1.464e-54
Identity = 116/360 (32.22%), Postives = 189/360 (52.50%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKD----IFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSE-GEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            +GH+W+  R F L  LRDFGLGK    E I  E  ++  + D    +  D          N+I++ I   RF   D   Q  ++ M +L + ++       + +  F      F+  + L   + DW+       +F  +I+ HR  +DF SE  +D  + +L K+ + +++ G  E F + Q     L+L +AG  TT+TT+NW   ++  +PD+ +K+++E  +++G +RL TM DK  L Y  AV++E  R +++ P+ L H T  D  ING+ + K + +   +    +D +I+  P  F P+ F  +D NG  K    E+LIPFS+GKRQC GE LAR E F+F  +   R++IS
Sbjct:    8 NGHMWSTHRRFALSTLRDFGLGKDLMQEKILIEVEDIFRKYDAQLGKEQDIQVVLNNAIANVINQTIFGYRF---DETNQEEFERMRHLVEYQEKQFATVKVYVEAFVPTIGKFLPGKSLDQLLDDWRN--SFYTFFDTQIENHRKKIDFDSEESQDYAEAYL-KEQKKQEALGEFELFSNTQFSNTCLDLWLAGVSTTNTTVNWTICYVLNHPDVLQKMNEEFDQVVGSDRLVTMGDKNNLPYFNAVLNESQRCANIVPINLFHATTKDTVINGYPVKKGTGVIAQISTVMLDEKIFPEPYKFNPDRF--IDENG--KPIKIEQLIPFSIGKRQCPGEGLARMEIFLFLANFFNRYKIS 357          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Match: cyp-33A1 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:Q27470])

HSP 1 Score: 187.963 bits (476), Expect = 5.299e-54
Identity = 121/362 (33.43%), Postives = 189/362 (52.21%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLI---LLMFPCLDQSFIVARLLFLFVSDWKRFV-KIQDYFAEEIKEHRNALDF-TSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFG 1082
            +G+ W   R F L  LRDFG+GK      IQ E   + +EL     + V+  E F +   NII++F+   RF              + L K  D+F  +   L ++      F+   ++ L   D  R    I  +F E+I+EHR  +DF TS+ +D ++ F+ K+ + +++ G+  SF + QL     ++ +AG  TT+ T+ +   F     D Q K+ KE++E+IG +R+ TM DK  L YT A ++E  R +++ PM L H    D  + G  IPK + +   + +   DPEI+E P  F PE +L  +S  + K    EEL+PFS+GKR CLGE LAR E F+F  +   R++ + G
Sbjct:  115 NGNTWKEHRKFALHTLRDFGMGKEAMEASIQLEVDKIDEELKKVEGKEVNIQEHFDLAIGNIINQFLFGNRFKDSS--------KFNELKKLLDLFFEVQGSLRVYFAYTVDFLPQWMVELLTPDVSRVRDGIYQFFDEQIEEHRQEIDFETSDSKDYVETFM-KEQKKREAEGDFASFSNEQLKNMCFDMWVAGMHTTTNTMGFLTAFALNNMDAQRKMQKELTEVIG-DRVVTMKDKLNLPYTNAFINEAQRCANLVPMNLPHAVTRDVQLLGCTIPKGTTVIHQISSVMSDPEIFEEPERFVPERYLD-ESGNLKKI---EELVPFSIGKRVCLGEGLARMELFLFTANSFNRYEFNCG 462          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Match: cyp-33E1 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:Q27482])

HSP 1 Score: 187.963 bits (476), Expect = 5.810e-54
Identity = 121/364 (33.24%), Postives = 192/364 (52.75%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKN----KDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTS-EGEDLMDRFLI--KQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGE 1085
            G  W  QR F L +LRDFGLGK    E +  E   ++D +   S + VD    F     ++I+  +   R+  D+ NI+   +  + + K+     +    ++ M P L           + + +W   + + + F ++  +   ++D+ S E  D ++ FL   K+HE +Q  G  E     QL     +L +AG ETTS TLNW  L++   P++++KV++E+   IG +R+ T  D+  LNY  A ++E  RL+++ PM L   T  D  I G+ IPKD++I P + +   DPEI+  P  F PE FL  D +     +  EEL+PFS+GKRQCLGE LA+ E F++F ++  +F I F E
Sbjct:  116 GDRWIQQRRFALHILRDFGLGKNLMEEKVLGEVTAMIDSIRK-SMEDVDMQNIFDASVGSVINNMLFGYRY--DETNIEEFLELKNRMNKHFKLAAEPMGGLIGMNPWLGHLPFFKGYKNVIMHNW---MGLMEMFRKQATDRLASIDYDSDEYSDYVEAFLKERKKHENEQDFGGFEM---EQLDSVCFDLWVAGMETTSNTLNWALLYVLLNPEVRQKVYEELEREIGSDRIITTTDRPKLNYINATVNESQRLANLLPMNLSRSTNADVEIAGYRIPKDTVITPQISSVMYDPEIFPEPYEFKPERFLESDGS----LKKVEELVPFSIGKRQCLGEGLAKMELFLYFANLFNKFDIKFHE 466          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Match: cyp-33E1 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:Q27482])

HSP 1 Score: 187.963 bits (476), Expect = 5.810e-54
Identity = 121/364 (33.24%), Postives = 192/364 (52.75%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKN----KDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTS-EGEDLMDRFLI--KQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGE 1085
            G  W  QR F L +LRDFGLGK    E +  E   ++D +   S + VD    F     ++I+  +   R+  D+ NI+   +  + + K+     +    ++ M P L           + + +W   + + + F ++  +   ++D+ S E  D ++ FL   K+HE +Q  G  E     QL     +L +AG ETTS TLNW  L++   P++++KV++E+   IG +R+ T  D+  LNY  A ++E  RL+++ PM L   T  D  I G+ IPKD++I P + +   DPEI+  P  F PE FL  D +     +  EEL+PFS+GKRQCLGE LA+ E F++F ++  +F I F E
Sbjct:  116 GDRWIQQRRFALHILRDFGLGKNLMEEKVLGEVTAMIDSIRK-SMEDVDMQNIFDASVGSVINNMLFGYRY--DETNIEEFLELKNRMNKHFKLAAEPMGGLIGMNPWLGHLPFFKGYKNVIMHNW---MGLMEMFRKQATDRLASIDYDSDEYSDYVEAFLKERKKHENEQDFGGFEM---EQLDSVCFDLWVAGMETTSNTLNWALLYVLLNPEVRQKVYEELEREIGSDRIITTTDRPKLNYINATVNESQRLANLLPMNLSRSTNADVEIAGYRIPKDTVITPQISSVMYDPEIFPEPYEFKPERFLESDGS----LKKVEELVPFSIGKRQCLGEGLAKMELFLYFANLFNKFDIKFHE 466          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Match: Cyp18a1 (gene:FBgn0010383 transcript:FBtr0074610)

HSP 1 Score: 182.57 bits (462), Expect = 1.695e-51
Identity = 121/402 (30.10%), Postives = 194/402 (48.26%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGL-----GKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFV-----KIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESF----VDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            G +W  QR FL   LR FG+     GK +  + I  E    +  L     Q VD S    +  +N+I   +M+ RF+ DDP  +     ++   +     H +          +I     F  +S  K  +     ++Q ++ + I +H+ + D  +   DL+D +L +  + K    + E F     + QL++  ++L  AG ET  TTL W  +FM + P    +V  E+ +++G+ RLPT+ D + L  T++ + E +R SS+ P+   H    D  +NG+ IP  S + P + + HMDP +WE P  F P  F  +D+ G  K +  E  IPF VG+R CLG+ LAR E F+FF S +  F I+    + E +   ++ GN G   T +      KRR
Sbjct:  137 GKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTV---------DYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFD-PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRF--IDTEG--KVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIA----LPEGQPLPSLKGNVGATITPESFKVCLKRR 520          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Match: Cyp18a1 (gene:FBgn0010383 transcript:FBtr0074609)

HSP 1 Score: 182.57 bits (462), Expect = 1.695e-51
Identity = 121/402 (30.10%), Postives = 194/402 (48.26%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGL-----GKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFV-----KIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESF----VDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            G +W  QR FL   LR FG+     GK +  + I  E    +  L     Q VD S    +  +N+I   +M+ RF+ DDP  +     ++   +     H +          +I     F  +S  K  +     ++Q ++ + I +H+ + D  +   DL+D +L +  + K    + E F     + QL++  ++L  AG ET  TTL W  +FM + P    +V  E+ +++G+ RLPT+ D + L  T++ + E +R SS+ P+   H    D  +NG+ IP  S + P + + HMDP +WE P  F P  F  +D+ G  K +  E  IPF VG+R CLG+ LAR E F+FF S +  F I+    + E +   ++ GN G   T +      KRR
Sbjct:  137 GKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTV---------DYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFD-PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRF--IDTEG--KVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIA----LPEGQPLPSLKGNVGATITPESFKVCLKRR 520          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Match: Cyp303a1 (gene:FBgn0001992 transcript:FBtr0343812)

HSP 1 Score: 160.614 bits (405), Expect = 8.926e-44
Identity = 104/371 (28.03%), Postives = 184/371 (49.60%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQI---------VDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVK----IQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMN-DKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQI 1073
            +  DG +W  QR F+L+ L++FG  ++  ++I+ NE   LL +L    D++         ++  +   +Y  N +   +  +R+    P I  + +T   L KN D+   +   FP L   FI         S +  FV+    +  + ++EI+ HR       E  DLMD +L  Q E     G    F D  L+   L++ +AG ETT+ +L +C + +   P+IQE+  +EI E++G ER+P  + D+  L Y +A+  E +R+  +   G+ HR   D  ++G+ IPKD+++        ++P  +  P +F P+ +L    +G  K    E   PF  G+ +C+G+ L R   F+F  +++Q F++
Sbjct:  119 LLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDL---KDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLL--RFIAPNF-----SGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKG---MFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL---FDGHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Match: Cyp303a1 (gene:FBgn0001992 transcript:FBtr0080828)

HSP 1 Score: 160.614 bits (405), Expect = 8.926e-44
Identity = 104/371 (28.03%), Postives = 184/371 (49.60%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQI---------VDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVK----IQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMN-DKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQI 1073
            +  DG +W  QR F+L+ L++FG  ++  ++I+ NE   LL +L    D++         ++  +   +Y  N +   +  +R+    P I  + +T   L KN D+   +   FP L   FI         S +  FV+    +  + ++EI+ HR       E  DLMD +L  Q E     G    F D  L+   L++ +AG ETT+ +L +C + +   P+IQE+  +EI E++G ER+P  + D+  L Y +A+  E +R+  +   G+ HR   D  ++G+ IPKD+++        ++P  +  P +F P+ +L    +G  K    E   PF  G+ +C+G+ L R   F+F  +++Q F++
Sbjct:  119 LLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDL---KDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLL--RFIAPNF-----SGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKG---MFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL---FDGHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Match: Cyp305a1 (gene:FBgn0036910 transcript:FBtr0074925)

HSP 1 Score: 156.762 bits (395), Expect = 2.937e-42
Identity = 103/360 (28.61%), Postives = 184/360 (51.11%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTR-DDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNAL--DFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGK---ERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQI 1073
            DG +W   R F +K +R+ G G+++    I+ E   LL +L+   +Q ++   +      N++   I  KR  R +D  ++ +   M+  +K  DI   +L  FP L +     R  +  +       ++  +F + I+EHR  L  D +    DL+  +L ++ + + + G   +F + QL+   L+  IAG +TTS T+N   + ++  PD+QEK+  +++  +     +  P ++ ++A +Y  A + EV R   + P+    R      + G+ IPK++ I  +L + H+D E W+ P  F PE F  +DS G  K    E  +PF +G+R+CLG++LAR+  F F V +VQ F +
Sbjct:  122 DGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWL-RHVAPDRTGYNLIQQLN--TELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYL-QEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERF--IDSAG--KCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSV 473          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Match: cyp2y3 (cytochrome P450, family 2, subfamily Y, polypeptide 3 [Source:ZFIN;Acc:ZDB-GENE-050522-490])

HSP 1 Score: 219.55 bits (558), Expect = 1.056e-65
Identity = 137/360 (38.06%), Postives = 196/360 (54.44%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN----IQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            +G  W   R F L  LRDFG+G+ +  + IQ E   LL   +    + VD + FF    +N+I   +  +RF  +D N    +Q I K +  L+      + I   FP + +SF       L     K    I+ +   ++KEH   LDF S+  D +D FLI+   L Q    +++ F    L+   L L +AG ETTSTTL +  + + K+P IQE++ +EI  +IG+ R+PTM D+K+L +T AV+ EV R   + P+ L H    D    G+ IPKD++I P L++   D   WE+P TF PEHF  LDSNG  K  P    +PFS GKR C+GESLAR E F+F VS++Q+F  S
Sbjct:  117 NGERWRQLRRFTLTTLRDFGMGRKRMEQWIQEESRYLLKSFEETKSKPVDPTFFFSRTVSNVICSLVFGQRFDYEDKNFLQLLQIISKLLRFLSSPWGQLYNI---FPQVMESFSSRHHAIL-----KDVENIRTFIRNKVKEHEQRLDF-SDPSDFIDCFLIR---LTQEKDKLDTEFHKDNLMATVLNLFVAGTETTSTTLRYALMLLIKHPQIQEQMQREIDRVIGQNRIPTMEDRKSLPFTDAVIHEVQRYMDIVPLSLPHYAMKDITFRGYKIPKDTVIIPMLHSVLRDEGHWETPWTFNPEHF--LDSNGNFKKNP--AFMPFSAGKRVCVGESLARMEIFLFIVSLLQKFSFS 460          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Match: cyp2y3 (cytochrome P450, family 2, subfamily Y, polypeptide 3 [Source:ZFIN;Acc:ZDB-GENE-050522-490])

HSP 1 Score: 216.853 bits (551), Expect = 9.882e-65
Identity = 136/360 (37.78%), Postives = 195/360 (54.17%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN----IQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            +G  W   R F L  LRDFG+G+ +  + IQ E   LL   +    + VD + FF    +N+I   +  +RF  +D N    +Q I K +  L+      + I   FP + +SF       L     K    I+ +   ++KEH   LDF S+  D +D FLI+   L Q    +++ F    L+   L L +AG ETTSTTL +  + + K+P IQE++ +EI  +IG+ R+PTM D+K+L +T AV+ EV R   + P+ L H    D    G+ IPKD++I P L++   D   WE+P TF PEHF  LDSNG  K  P    +PFS GKR C+GESLA  E F+F VS++Q+F  S
Sbjct:  117 NGERWRQLRRFTLTTLRDFGMGRKRMEQWIQEESRYLLKSFEETKSKPVDPTFFFSRTVSNVICSLVFGQRFDYEDKNFLQLLQIISKLLRFLSSPWGQLYNI---FPQVMESFSSRHHAIL-----KDVENIRTFIRNKVKEHEQRLDF-SDPSDFIDCFLIR---LTQEKDKLDTEFHKDNLMATVLNLFVAGTETTSTTLRYALMLLIKHPQIQEQMQREIDRVIGQNRIPTMEDRKSLPFTDAVIHEVQRYMDIVPLSLPHYAMKDITFRGYKIPKDTVIIPMLHSVLRDEGQWETPWTFNPEHF--LDSNGNFKKNP--AFMPFSAGKRSCVGESLASMELFLFTVSLLQKFTFS 460          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Match: cyp2k19 (cytochrome P450, family 2, subfamily k, polypeptide 19 [Source:ZFIN;Acc:ZDB-GENE-091211-1])

HSP 1 Score: 208.764 bits (530), Expect = 9.296e-63
Identity = 126/377 (33.42%), Postives = 192/377 (50.93%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN-IQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFL-FVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYS-QTIIG 1124
            +F +G  W   R F L  LRDFG+GK  S E I  E  +L  E D F  +  D ++      +NIIS  +   RF   DP   + + +  +N+     +      MFP +       R++    +    +  K+     E +  +        +    +D FL ++   ++S      F +  LI     L +AG +TT TTL W  + M+KYP IQ++V +EI  +IG  R P + D+K L YT AV+ E+ RL+++ P+ L H+T  D   NG++I K + + P L +   D   WE P +FYPEHF  LD  G  ++  R+  IPFS G+R CLGESLAR E F+FF S++Q ++ +    +SED    + I+G
Sbjct:    8 LFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSVSMWFHEMFPWVGPFLKSKRIIVENIIQSRAQMTKLITALLETLNPN--------DPRGFVDSFLTRKLSDEKSGKKDSYFHEENLIMTVTNLFVAGTDTTGTTLRWGLMLMAKYPQIQDRVQEEIDRVIGG-RQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHKTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHF--LDEKG--QFVKRDAFIPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVG 371          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Match: cyp2k21 (cytochrome P450, family 2, subfamily k, polypeptide 21 [Source:ZFIN;Acc:ZDB-GENE-091113-17])

HSP 1 Score: 209.534 bits (532), Expect = 7.713e-62
Identity = 128/377 (33.95%), Postives = 194/377 (51.46%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN-IQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFL-FVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYS-QTIIG 1124
            +F +G  W   R F L  LRDFG+GK  S E I  E  +L  E D F  +  D ++      +NIIS  +   RF   DP   + + +  +N+     I   +  +FP L       R++    +    +  K+     E +  +        +    +D FLI++   ++S      F +  L+     L IAG +TT TTL W  + M+KYP IQ++V +EI  +IG  R P + D+K L YT AV+ E+ RL+++ P+ L HRT  D   NG++I K + + P L +   D   WE P +FYPEHF  LD  G  ++  R+  +PFS G+R CLGESLAR E F+FF S++Q ++ +    +SED    + I+G
Sbjct:  128 LFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMWLYDIFPWLGPFLKNKRIIVENIIQSRVQMTKLITALLETLNPN--------DPRGFVDSFLIRKLSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGG-RQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHF--LDEKG--QFVRRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVG 491          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Match: cyp2p8 (cytochrome P450, family 2, subfamily P, polypeptide 8 [Source:ZFIN;Acc:ZDB-GENE-061030-1])

HSP 1 Score: 207.994 bits (528), Expect = 2.111e-61
Identity = 132/360 (36.67%), Postives = 194/360 (53.89%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEI-IQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTM-DNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            +   G+ W  QR F L  LR+FGLGK KSLE  I  EC  L + +     +  D         +N+I   +   RF   D + Q + K + + +     I + +  MFP L +           ++ W+   K+ D+  E++ EHR   D  S   D +D FL +  +LK  T     F    L   SL+L +AG ETTSTTL W  L+M KYP+IQ KV +EI  ++G  R P+++D+  + YT AV+ E+ R+ ++AP+ L   T +D  I  + IPK +++  NL +   D   WE+P +F P HF  LD+ G  K++ R+  +PFS+GKR CLGE LAR E F+FF S++QRF  S
Sbjct:  121 ILSSGYKWKHQRRFALSTLRNFGLGK-KSLEPSINVECGFLNEAISNEQGRPFDPRLLLNNAVSNVICVLVFGNRFDYSDHHFQTLLKNISEAVYLEGSICNQLYNMFPWLMERLPGPHKTI--ITLWR---KVTDFVREKVNEHRVDYD-PSNPRDYIDCFLTEMEKLKDDTA--AGFDVENLCICSLDLFVAGTETTSTTLYWGLLYMIKYPEIQAKVQEEIDAVVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIAPINLARSTSEDTQIGNYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHF--LDAEG--KFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFS 467          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Match: cyp11a1 (cytochrome P450 family 11 subfamily A member 1 [Source:Xenbase;Acc:XB-GENE-960779])

HSP 1 Score: 214.157 bits (544), Expect = 1.749e-63
Identity = 130/361 (36.01%), Postives = 188/361 (52.08%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN-IQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQR--FQISFGE 1085
            G  W   R F L  LRDFG+GK    E +++E   L D   +      D         +N+I   I  +RF  DD   ++ +    +++         I+   P   +   +ARL F      +  + +  Y  E I EH+   D +    D +D F++   E+K++ G  +S F D  L+  + +L  AG ETT+TTL W  LFM  YPD+Q KV +EI ++IG+ R PTM D   + YT AV+ E+ R   + P+ + H  + D +I GF+IPK ++I  NL +   D ++WE P  FYPEHFL  D     K+  RE  + FS G+R CLGE LAR E F+FF S++QR  FQI  GE
Sbjct:  134 GQSWKDLRRFTLSTLRDFGMGKKSLEERVRDEAGYLCDAFQSEQGGPFDPHVLINTAVSNVICSIIFGERFEYDDHKFLKLLCLIEESIKAESGPVPQIISSLPWSSKVPGLARLFF------QPRIHMLQYLQEIINEHKQTWD-SGHTRDFIDAFML---EMKKAKGVKDSNFNDQNLLLTTADLFSAGSETTTTTLRWGLLFMLLYPDVQRKVQEEIDQVIGRTRKPTMGDVLQMPYTNAVIHEIQRYGDIIPLSVPHMAYRDTHIKGFFIPKGTVIMTNLSSVLKDEKVWEKPFQFYPEHFLDRD----GKFVKREAFMAFSAGRRVCLGEQLARMELFLFFSSLLQRFSFQIPDGE 480          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Match: cyp11a1 (cytochrome P450 family 11 subfamily A member 1 [Source:Xenbase;Acc:XB-GENE-960779])

HSP 1 Score: 213.386 bits (542), Expect = 4.274e-63
Identity = 129/361 (35.73%), Postives = 188/361 (52.08%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN-IQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQR--FQISFGE 1085
            G  W   R F L  LRDFG+GK    E +++E   L D   +      D         +N+I   I  +RF  DD   ++ +    +++         I+   P   +   +ARL F      +  + +  Y  E I EH+   D +    D +D F++   E+K++ G  +S F D  L+  + +L  AG ETT+TTL W  LFM  YPD+Q KV +EI ++IG+ R PTM D   + YT AV+ E+ R   + P+ + H  + D +I GF+IPK ++I  NL +   D ++WE P  FYPEHF+  D     K+  RE  + FS G+R CLGE LAR E F+FF S++QR  FQI  GE
Sbjct:  134 GQSWKDLRRFTLSTLRDFGMGKKSLEERVRDEAGYLCDAFQSEQGGPFDPHVLINTAVSNVICSIIFGERFEYDDHKFLKLLCLIEESIKAESGPVPQIISSLPWSSKVPGLARLFF------QPRIHMLQYLQEIINEHKQTWD-SGHTRDFIDAFML---EMKKAKGVKDSNFNDQNLLLTTADLFSAGSETTTTTLRWGLLFMLLYPDVQRKVQEEIDQVIGRTRKPTMGDVLQMPYTNAVIHEIQRYGDIIPLSVPHMAYRDTHIKGFFIPKGTVIMTNLSSVLKDEKVWEKPFQFYPEHFIDRD----GKFVKREAFMAFSAGRRVCLGEQLARMELFLFFSSLLQRFSFQIPDGE 480          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Match: cyp11a1 (cytochrome P450 family 11 subfamily A member 1 [Source:Xenbase;Acc:XB-GENE-960779])

HSP 1 Score: 211.075 bits (536), Expect = 2.577e-62
Identity = 129/361 (35.73%), Postives = 186/361 (51.52%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN-IQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQR--FQISFGE 1085
            G  W   R F L  L+DFG+GK    E +  E   L D   +      D         +N+I   I  +RF  DD   ++ +    +++         I+   P   +   +ARL F      +  + +  Y  E I EH+   D +    D +D F++   E+K++ G  +S F D  L+  + +L  AG ETT+TTL W  LFM  YPD+Q KV +EI ++IG+ R PTM D   + YT AV+ E+ R   + P+ + H  + D +I GF+IPK ++I  NL +   D ++WE P  FYPEHFL  D     K+  RE  + FS G+R CLGE LAR E F+FF S++QR  FQI  GE
Sbjct:  134 GQSWKDLRRFTLSTLKDFGMGKKSLEERVGEEAGYLCDAFQSEQGGPFDPHVLINTAVSNVICSIIFGERFEYDDHKFLKLLCLIEESIKAESGPVPQIISSLPWSSKVPGLARLFF------QPRIHMLQYLQEIINEHKQTWD-SGHTRDFIDAFML---EMKKAKGVKDSNFNDQNLLLTTADLFSAGSETTTTTLRWGLLFMLLYPDVQRKVQEEIDQVIGRTRKPTMGDVLQMPYTNAVIHEIQRYGDIIPLSVPHMAYRDTHIKGFFIPKGTVIMTNLSSVLKDEKVWEKPFQFYPEHFLDRD----GKFVKREAFMAFSAGRRVCLGEQLARMELFLFFSSLLQRFSFQIPDGE 480          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Match: cyp11a1 (cytochrome P450 family 11 subfamily A member 1 [Source:Xenbase;Acc:XB-GENE-960779])

HSP 1 Score: 210.305 bits (534), Expect = 7.396e-62
Identity = 129/366 (35.25%), Postives = 189/366 (51.64%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN-IQFIWKTMDNLAKNKDIFHLIL-----LMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQR--FQISFGE 1085
            G  W   R F L  LRDFG+GK    E +++E   L D   +      D         +N+I   I  +RF  DD   ++ +    +++         ++     +  P   +   +ARL F      +  + +  Y  E I EH+   D +    D +D F++   E+K++ G  +S F D  L+  + +L  AG ETT+TTL W  LFM  YPD+Q KV +EI ++IG+ R PTM D   + YT AV+ E+ R   + P+ + H  + D +I GF+IPK ++I  NL +   D ++WE P  FYPEHFL  D     K+  RE  + FS G+R CLGE LAR E F+FF S++QR  FQI  GE
Sbjct:  134 GQSWKDLRRFTLSTLRDFGMGKKSLEERVRDEAGYLCDAFQSEQGGPFDPHVLINTAVSNVICSIIFGERFEYDDHKFLKLLCLIEESIKAESGPVPQVMKDNKKISLPWSSKVPGLARLFF------QPRIHMLQYLQEIINEHKQTWD-SGHTRDFIDAFML---EMKKAKGVKDSNFNDQNLLLTTADLFSAGSETTTTTLRWGLLFMLLYPDVQRKVQEEIDQVIGRTRKPTMGDVLQMPYTNAVIHEIQRYGDIIPLSVPHMAYRDTHIKGFFIPKGTVIMTNLSSVLKDEKVWEKPFQFYPEHFLDRD----GKFVKREAFMAFSAGRRVCLGEQLARMELFLFFTSLLQRFSFQIPDGE 485          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Match: ENSXETT00000056215.1 (cytochrome P450 2D20-like [Source:NCBI gene;Acc:100494106])

HSP 1 Score: 207.608 bits (527), Expect = 1.639e-61
Identity = 128/353 (36.26%), Postives = 183/353 (51.84%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQ-FIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRF 1067
            G  W   R F +   RDFG+GK    E ++ E   L   +     +  D         +N+    I  +R+   D  IQ  ++   +       +   IL  FP L +       LF   +D+  ++K +      IKEH++  D  +   D +D F     E++++  N +S F +  L+    +L +AG ETTS TL W  L M + P IQ+KVH+EI ++IG+ R+P M D++ + YT AV+ E  R  ++ P  L H  + D NI GF IPK + I PNL +   D  IWE P  FYPEHF  LDS G  K+  RE  IPFS GKR C GE+LA++E F+FFVS+ QRF
Sbjct:   79 GQSWKDLRRFSISTFRDFGMGKKTIEEPVREEAGYLCTAIQAKEGRPFDPFLLLNQAVSNLNCSIIFGERYDYSDAAIQRLLFLLQERFHLETGVISQILNNFPRLIKIAGPHLKLFKVQNDYLNYLKAK------IKEHKDTWD-PAVTRDYVDAFF---EEIEKTKDNPQSSFTETSLLFTIADLFVAGSETTSNTLRWSILMMLRNPHIQDKVHQEIDQVIGRNRIPKMEDQRNMPYTNAVIHETQRYGNILPTALFHMAYRDTNIQGFNIPKGTTIIPNLTSVLKDETIWERPYQFYPEHF--LDSEG--KFVKREAFIPFSAGKRMCAGEALAKTELFLFFVSLFQRF 417          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Match: Cyp2j13 (cytochrome P450, family 2, subfamily j, polypeptide 13 [Source:MGI Symbol;Acc:MGI:2385197])

HSP 1 Score: 225.713 bits (574), Expect = 5.728e-68
Identity = 138/362 (38.12%), Postives = 203/362 (56.08%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLE-IIQNECLNLLDELDTFSDQIVDFSEFFPIYT--TNIISRFIMNKRFTRDDPNIQFIWKTMDN---LAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTG-NVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRF 1067
            +F  G  W  QR F L  LR+FGLGK KSLE  IQ E  +L++ +     Q   F   F IY+  +NII      +RF   D   Q + + +D    L     + HL  + FP + +         L  + W+   K++ Y A+ I  HR   +   E  D +D FL   +E+ +  G    SF +  LI ++L+L +AG ETTS+TL W  L+M+ YP++QE V  EI  +IG+ + P++ D+ ++ YT AV+ E+LR+ +  P+ +      D  + GF++PK S++  NL A HMDP+ W +P  F PEHFL    NG  +++ RE  +PFS+GKR CLGE LARSE FIFF ++VQ+F
Sbjct:  127 IFSSGQTWKEQRRFALMTLRNFGLGK-KSLEHRIQEEASHLVEAIGEEEGQ--PFDPHFKIYSAVSNIICSITFGERFEYHDSQFQELLQLLDKAMYLGTTSLMVHLYNI-FPWITKHLPGQHQTLL--ATWR---KLKSYIADIIDNHRKDWN-PDEPRDFIDAFL---NEMAKYPGKTTTSFNEENLICSTLDLFLAGTETTSSTLRWALLYMALYPEVQENVQAEIDRVIGQSKHPSLADRDSMPYTNAVVHEILRMGNSVPLNIPREVAVDTTLAGFHLPKRSVVMTNLTALHMDPKEWATPDIFNPEHFL---ENG--QFKKRESFLPFSMGKRACLGEQLARSELFIFFTALVQKF 470          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Match: Cyp2b19 (cytochrome P450, family 2, subfamily b, polypeptide 19 [Source:MGI Symbol;Acc:MGI:107303])

HSP 1 Score: 219.935 bits (559), Expect = 6.131e-66
Identity = 129/366 (35.25%), Postives = 195/366 (53.28%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN----IQFIWKT---MDNLAKNK-DIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            +F  G  W   R F L  +RDFG+GK    E I+ E   L++EL  +    ++ + +F     NII   +  +RF   D      +  I++T   M +L+    ++F  IL  FP   +               K   +I DY    +++HR  LD  S   D +D +L++    K+ + +   F    L+ + L L  AG ETTSTTL +  L M KYP + EKV KEI ++IG  RLPT++D+  + YT AV+ E+ R + +AP+GL H+   D    G+ IPK++ ++P L +   DP  +E P +F PEHF  LD+NG  K    E  +PFS GKR CLGE +AR+E F+FF +++Q F ++
Sbjct:  115 IFSSGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYKGAPLNPTFYFQCIVANIICSIVFGERFDYKDHQFLHLLNLIYQTFSLMSSLSSQVFELFSAILKYFPGAHRQI------------SKNLQEILDYIGHSVEKHRATLD-PSAPRDFIDTYLLRME--KEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFTDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHF--LDANGALKTN--EAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSLA 461          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Match: Cyp2j6 (cytochrome P450, family 2, subfamily j, polypeptide 6 [Source:MGI Symbol;Acc:MGI:1270148])

HSP 1 Score: 219.164 bits (557), Expect = 1.756e-65
Identity = 134/375 (35.73%), Postives = 205/375 (54.67%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPI--YTTNIISRFIMNKRFTRDDPNIQFIWKTMDN--------LAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISE 1097
            +F  G IW  QR F L  LR+FGLGK    E +Q E  +L++ +    ++   F+  F I    +NII      +RF   D   Q + + +D         +++  +IF  I+   P   Q             +W+   K++ + +  I +HR   +   E  D +D FL    E+ +      SF +  LI ++L+L  AG ETTSTTL W  L+M+ YP++QEKV  EI  +IG++R   + D++++ YT AV+ EV R+ ++ P+ +      D N+NGF++PK +++  NL A H DP+ W +P  F PEHFL    NG  +++ RE  +PFS+GKR CLGE LARSE FIFF S++Q+F  +F   I+E
Sbjct:  127 IFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIR--EEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVF---------RNWE---KLKLFVSCMIDDHRKDWN-PDEPRDFIDAFL---KEMTKYPEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFL---ENG--QFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKF--TFNPPINE 476          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Match: Cyp2b9 (cytochrome P450, family 2, subfamily b, polypeptide 9 [Source:MGI Symbol;Acc:MGI:88600])

HSP 1 Score: 215.698 bits (548), Expect = 2.872e-64
Identity = 128/365 (35.07%), Postives = 196/365 (53.70%), Query Frame = 3
Query:    6 FKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN----IQFIWKTMDNLAKNK----DIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            F  G  W   R F L  +++FG+GK    E I+ E   L++EL  +    +D +  F   T NII   +  +RF   D      +  ++K    L+       ++F   L  FP + +  +            K+  ++ DY A  +++H+  LD  S   D +D +L++  E ++S  N E F    L+ + L L  AG ETTS TL++  L M KYP + EKV KEI ++IG  RLPT++D+  + YT AV+ E+ R S + P+GL H+   D    G+ +PK++ ++P L +   DP+ +E P  F PEHF  LD+NG  K    E  +PFS GKR CLGES+AR+E FIFF +++Q F ++
Sbjct:  115 FASGQRWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGVPLDPTFLFQCITANIICSIVFGERFDYTDDQFLHLLNLMYKIFSLLSSFSGQMFELFSGFLKYFPGVHRQIV------------KKQQELLDYIAHSVEKHKATLD-PSAPRDYIDTYLLRM-EKEKSNHNTE-FHHQNLMMSVLSLFFAGTETTSATLHYGVLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHF--LDANGALKKC--EAFLPFSTGKRICLGESIARNELFIFFTTILQNFSVA 460          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Match: Cyp2d12 (cytochrome P450, family 2, subfamily d, polypeptide 12 [Source:MGI Symbol;Acc:MGI:88604])

HSP 1 Score: 216.083 bits (549), Expect = 3.197e-64
Identity = 131/356 (36.80%), Postives = 189/356 (53.09%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTM-DNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            G  W  QR F L  LR+FGLG+    E +  E  +L D   T + Q ++ +      T N+I+  I  +RF  +DP +  + K + D+L +   +   ++  FP L     + RL   F+   K F+ I D     + E+R   D      +L D FL    E++++ GN ES F D  L    ++L  AG  TTSTTL+W  L M  +PD+Q +V +EI E+IG+ R P M D+  + YT AV+ EV R   + P+ L   T  D  +  F IPK +++ PN+ + HMD  +WE P  F+PEHF  LD+ G   +   E  I FS G+R CLGE LAR E F+FF  ++QRF  S
Sbjct:  128 GPEWREQRRFSLSSLRNFGLGRKSLEEWVIKEAGHLCDAFTTQAGQYINPNTMLKKATCNVIASLIFARRFEYEDPYLIRMLKVLEDSLTELSGLIPEVINTFPIL---LHIPRLADKFLQSQKSFIAIVDNL---LTENRTTWDPAQSPRNLTDAFLA---EIEKAKGNPESSFNDENLRMVVIDLFTAGILTTSTTLSWALLLMILHPDVQRRVQQEIDEVIGQVRHPEMADQAHMPYTNAVIHEVQRFGDIVPLHLPRITSRDIEVQDFLIPKGTILLPNMSSVHMDDTVWEKPLRFHPEHF--LDAQG--HFVKHEAFITFSAGRRSCLGEPLARMELFLFFTCLLQRFSFS 470          
BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Match: sp|Q27712|CP2L1_PANAR (Cytochrome P450 2L1 OS=Panulirus argus OX=6737 GN=CYP2L1 PE=1 SV=1)

HSP 1 Score: 224.172 bits (570), Expect = 1.098e-66
Identity = 131/387 (33.85%), Postives = 212/387 (54.78%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHL--------ILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQ---STGNVESFVDWQLIRNS-LELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISF--GEEISEDRYSQTII 1121
            +F +G +W   R F+L+ LRD G+GK++    IQ+E   L+ EL   +DQ +   +   +   N+I + + + R++  D   Q+  + +     N   F L        +L++ P   ++++  R+L   V +      ++DY    IKEH+  LD  S  +DL+D +LI   E K+   ST N+E+      +R   ++L  AG ETTST + W  L++ KYP++Q K+ +EI   + +  LP++  K  L Y +A + EV R+ S+ P+G+ H T  D  + G+ +PK +++  +L  CH DP  WE P  FYPEHF  LD  G  K+  RE L+ FSVG+R C+GESLAR E F+F  +++Q F  S   GE +  ++  Q ++
Sbjct:  108 VFSNGVMWQTHRRFILRQLRDLGMGKSRLEAAIQHEAACLVQELKKHTDQPMPLPKSINLAVLNVIWKLVADHRYSLQDQEGQYFTQLLTTTTDNMQGFALNLFNYLPWLLMITPDFVKNWMGVRVLRDGVCE------LKDYMKTFIKEHQATLD-PSNPKDLLDAYLIDLQERKEDPLSTMNIET------VRAVIMDLFGAGTETTSTMIRWTILYLMKYPEVQAKIQREIDAAVPRGTLPSLEHKDKLAYFEATIHEVHRIVSLVPLGVSHYTNQDTELAGYRLPKGTVVMSHLECCHRDPSYWEKPNEFYPEHF--LDDQG--KFVKREHLVNFSVGRRVCVGESLARMELFVFLSAILQNFTFSAPKGEVLHTEKDPQQML 477          
BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Match: sp|O55071|CP2BJ_MOUSE (Cytochrome P450 2B19 OS=Mus musculus OX=10090 GN=Cyp2b19 PE=2 SV=1)

HSP 1 Score: 219.935 bits (559), Expect = 4.289e-65
Identity = 129/366 (35.25%), Postives = 195/366 (53.28%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPN----IQFIWKT---MDNLAKNK-DIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            +F  G  W   R F L  +RDFG+GK    E I+ E   L++EL  +    ++ + +F     NII   +  +RF   D      +  I++T   M +L+    ++F  IL  FP   +               K   +I DY    +++HR  LD  S   D +D +L++    K+ + +   F    L+ + L L  AG ETTSTTL +  L M KYP + EKV KEI ++IG  RLPT++D+  + YT AV+ E+ R + +AP+GL H+   D    G+ IPK++ ++P L +   DP  +E P +F PEHF  LD+NG  K    E  +PFS GKR CLGE +AR+E F+FF +++Q F ++
Sbjct:  115 IFSSGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYKGAPLNPTFYFQCIVANIICSIVFGERFDYKDHQFLHLLNLIYQTFSLMSSLSSQVFELFSAILKYFPGAHRQI------------SKNLQEILDYIGHSVEKHRATLD-PSAPRDFIDTYLLRME--KEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFTDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHF--LDANGALKTN--EAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSLA 461          
BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Match: sp|O54750|CP2J6_MOUSE (Cytochrome P450 2J6 OS=Mus musculus OX=10090 GN=Cyp2j6 PE=2 SV=2)

HSP 1 Score: 219.164 bits (557), Expect = 1.229e-64
Identity = 134/375 (35.73%), Postives = 205/375 (54.67%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPI--YTTNIISRFIMNKRFTRDDPNIQFIWKTMDN--------LAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISE 1097
            +F  G IW  QR F L  LR+FGLGK    E +Q E  +L++ +    ++   F+  F I    +NII      +RF   D   Q + + +D         +++  +IF  I+   P   Q             +W+   K++ + +  I +HR   +   E  D +D FL    E+ +      SF +  LI ++L+L  AG ETTSTTL W  L+M+ YP++QEKV  EI  +IG++R   + D++++ YT AV+ EV R+ ++ P+ +      D N+NGF++PK +++  NL A H DP+ W +P  F PEHFL    NG  +++ RE  +PFS+GKR CLGE LARSE FIFF S++Q+F  +F   I+E
Sbjct:  127 IFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIR--EEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVF---------RNWE---KLKLFVSCMIDDHRKDWN-PDEPRDFIDAFL---KEMTKYPEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFL---ENG--QFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKF--TFNPPINE 476          
BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Match: sp|P51589|CP2J2_HUMAN (Cytochrome P450 2J2 OS=Homo sapiens OX=9606 GN=CYP2J2 PE=1 SV=2)

HSP 1 Score: 217.624 bits (553), Expect = 5.495e-64
Identity = 132/364 (36.26%), Postives = 197/364 (54.12%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDN---LAKNK-----DIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGN-VESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRF 1067
            +   G  W  QR F L  LR+FGLGK    E IQ E  +L + +   + Q  D         +NII      +RF   D   Q + K +D    L  +K     ++F  I+   P   Q+           S+WK   K++ + +  I +HR   +  +E  D +D +L    E+ + TGN   SF +  LI ++L+L  AG ETTSTTL W  L+M+ YP+IQEKV  EI  +IG+ + P+   ++++ YT AV+ EV R+ ++ P+ +      D  + G+++PK ++I  NL A H DP  W +P TF P+HFL    NG  +++ RE  +PFS+GKR CLGE LAR+E FIFF S++Q+F
Sbjct:  127 IMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLF---------SNWK---KLKLFVSHMIDKHRKDWN-PAETRDFIDAYL---KEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL---ENG--QFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469          
BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Match: sp|P24460|CP2BB_CANLF (Cytochrome P450 2B11 OS=Canis lupus familiaris OX=9615 GN=CYP2B11 PE=2 SV=1)

HSP 1 Score: 217.238 bits (552), Expect = 5.588e-64
Identity = 129/366 (35.25%), Postives = 193/366 (52.73%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDP------NIQFIWKTMDNLAKNK--DIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            +F +G  W   R F L  +RDFG+GK    E IQ E   L++EL      + D + FF   T NII   +  KRF   DP      N+ ++   + +   ++  ++FH  L  FP   +              +    +I+ + A  +++HR  LD  S   D +D +LI+  + K    +   F    LI  +L L  AG ETTSTTL +  L M KYP I E+++KEI ++IG  RLP+++D+  + YT AV+ E+ R   + P+G+ H    D    G+ IPK + +FP L++   DP  +E P  F P+HF  LD+NG  K    E  IPFS+GKR CLGE +AR E F+FF +++Q F ++
Sbjct:  114 VFANGERWKTLRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKTEGVLQDPTFFFHSMTANIICSIVFGKRFGYKDPEFLRLMNLFYVSFALISSFSSQMFELFHSFLKYFPGTHRQV------------YNNLQEIKAFIARMVEKHRETLD-PSAPRDFIDAYLIRMDKEKAEPSS--EFHHRNLIDTALSLFFAGTETTSTTLRYGFLLMLKYPHIAERIYKEIDQVIGPHRLPSLDDRAKMPYTDAVIHEIQRFGDLLPIGVPHMVTKDICFRGYIIPKGTEVFPILHSALNDPHYFEKPDVFNPDHF--LDANGALKKN--EAFIPFSIGKRICLGEGIARMELFLFFTTILQNFSVA 460          
BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Match: A0A4P8NYX5 (P450 2B-like protein OS=Dugesia japonica OX=6161 GN=p4502B PE=2 SV=1)

HSP 1 Score: 502.671 bits (1293), Expect = 1.684e-172
Identity = 243/392 (61.99%), Postives = 308/392 (78.57%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            +FKDG  W+ QRSF+LKVLRDFGLGK+KS++++QNEC  LL+EL++   +I+DFS+  PIYT NIIS+FIMNKRF R++P I  I K +    K KDI  L+ +MFP  D S +   L+  F S WK F++IQ+YF EEI EH   +DF SEGEDLMDRFLIKQ++LKQ   +V SF DWQLIR+SLEL  AGYETTSTTL W  LFMSK+ DIQ+KVH EI EIIGKERLPTMNDKK++NYTQAVMDE+ R+SSVAP+ LIHRT +DANI+G++IPK++LIFPNLYACH D +IWE P  FYPEHFL+ D NG  KY PR+ELI FS+GKRQCLGESLAR E+FIFF S++QRF++   +E++E  Y + ++G +G+IR S + +F+F ++
Sbjct:  115 IFKDGQDWSTQRSFVLKVLRDFGLGKSKSVDLVQNECSFLLEELESLEGKIIDFSKIIPIYTANIISKFIMNKRFERENPKIARIEKMLSEEIKKKDIIQLLHIMFPKCDTSGLFCELIINFTSKWKEFLEIQNYFKEEIDEHLKTIDFNSEGEDLMDRFLIKQNQLKQQNIDVGSFNDWQLIRSSLELFYAGYETTSTTLCWSFLFMSKHQDIQQKVHNEIIEIIGKERLPTMNDKKSMNYTQAVMDEIFRMSSVAPLALIHRTLNDANIDGYFIPKNTLIFPNLYACHFDRDIWEKPMIFYPEHFLTEDDNGNLKYTPRDELILFSIGKRQCLGESLARMEFFIFFTSILQRFRVKLVKELNEKEYEEALLGKDGIIRGSIVNDFIFTKQ 506          
BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Match: A0A2U8U473 (Cytochrome P450 2K1-like protein OS=Dugesia japonica OX=6161 GN=P450 PE=2 SV=1)

HSP 1 Score: 488.034 bits (1255), Expect = 9.767e-167
Identity = 231/390 (59.23%), Postives = 299/390 (76.67%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFK 1172
            +FKDG +W+ QRSF+LKVLRDFG+GK+ S +I+Q ECL LL+ELD+   +I+DFS+  PIYT NIIS+FIMNKRF R DP I+FI   +   +K  DI   + LMFP  D+S I+++      S  + F K++  F +EI+EH+  LD+ SEG+DL+DRFL++Q+ L QSTG VESF D QLI  + E+  AGYETTSTTL W  LFMS+Y DIQ+KV++EI  +IG+ER+PTMNDKK+LNYTQAVMDE+LRLSSVAP+G+ HRTF+D +++ ++IPK+SL+F N YACH DP+IW  P  FYPEHFL    N   KY PREELIPF +GKRQC+GESLAR EYFIFFVS++QR+Q+ F E IS+  + +T+ GNEG+IR S IKNF+FK
Sbjct:  115 VFKDGPVWSTQRSFILKVLRDFGMGKSISQDIVQGECLFLLNELDSLQGEIIDFSKIIPIYTANIISKFIMNKRFDRSDPRIKFIEYAIFQTSKQSDIVQRLHLMFPIFDKSTIISKFNLWITSKLQLFSKVERVFHDEIEEHKTNLDYNSEGDDLIDRFLLEQNRLSQSTGIVESFTDKQLIFMTFEMFGAGYETTSTTLGWSMLFMSRYKDIQKKVYEEILNVIGEERMPTMNDKKSLNYTQAVMDEILRLSSVAPLGIFHRTFNDTSVDNYFIPKNSLVFANYYACHTDPDIWLKPVEFYPEHFLIKCENDELKYSPREELIPFGIGKRQCIGESLARMEYFIFFVSILQRYQVDFSENISDSLFEETLRGNEGIIRYSKIKNFIFK 504          
BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Match: A0A1I8I1X1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013417g1 PE=3 SV=1)

HSP 1 Score: 253.062 bits (645), Expect = 6.673e-75
Identity = 147/394 (37.31%), Postives = 211/394 (53.55%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRF-TRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDW---KRFVKIQDYFAE-EIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            +G +W   R F LKVLRDFG  +A + + I  E  +L D+ +T  +  VD +E       N+IS  +   R  ++DD    F+  T +NL +  D+   I + FP L Q   V RLL L   D    +R +K+   F + +I  HR  L   S   D +D FL++Q +L     +  +F D+QL R   EL +AG +TTS T+ W  L+   YP+ Q +V  EI   IG++RLP   D+K + YT A +DEV R +++AP  ++HR   D    G+ I  D LI  NLY  H DPE+W SP  F PE FL++D+    +YQP E L+PF VGKR CLGESLAR E F+F   ++Q+       + S        IG++G++        +F  R
Sbjct:  132 EGELWREHRRFALKVLRDFGFARAGTEDSIHQELQDLRDQFNTAGEAGVDTTEVLCRAIANVISMMLFGYRAGSQDDRFEAFLAATQENL-QGGDLARFIPVGFPLLYQIPGVMRLLELLGVDVYVVQRNLKVTHGFCQMQIDAHRAQLAGVSSPNDFLDAFLMEQEKLNGRKKD-HTFDDFQLKRTLTELFVAGTDTTSNTIRWALLYACLYPECQARVQAEIDAQIGRDRLPEHRDRKRMPYTLAFIDEVQRFATLAPFAVLHRCPRDVEFMGYDISSDDLIMTNLYGIHHDPELWSSPEAFQPERFLAVDTG---EYQPNEHLVPFGVGKRACLGESLARQELFLFIAGILQQHSARLHPD-SVKNLEDIKIGSDGIVHAPGAHRIIFSAR 519          
BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Match: A0A1I8HTI6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013417g2 PE=3 SV=1)

HSP 1 Score: 252.677 bits (644), Expect = 1.010e-74
Identity = 147/394 (37.31%), Postives = 210/394 (53.30%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRF-TRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDW---KRFVKIQDYFAE-EIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            +G +W   R F LKVLRDFG  +A + + I  E  +L D+ +T  +  VD +E       N+IS  +   R  ++DD    F+  T +NL +  D+   I + FP L Q   V RLL L   D    +R +K+   F + +I  HR  L   S   D +D FL++Q +L     +  +F D+QL R   EL +AG +TTS T+ W  L+   YP+ Q +V  EI   IG+ RLP   D+K + YT A +DEV R +++AP  ++HR   D    G+ I  D LI  NLY  H DPE+W SP  F PE FL++D+    +YQP E L+PF VGKR CLGESLAR E F+F   ++Q+       + S        IG++G++        +F  R
Sbjct:  132 EGELWREHRRFALKVLRDFGFARAGTEDSIHQELQDLRDQFNTAGEAGVDTTEVLCRAIANVISVMLFGYRAGSQDDRFEAFLAATQENL-QGGDLARFIPVGFPLLYQIPGVMRLLELLGVDVYVVQRNLKVTHGFCQMQIDAHRAQLAGVSSPNDFLDAFLMEQEKLNGRKKD-HTFDDFQLKRTLTELFVAGTDTTSNTIRWALLYACLYPECQARVQAEIDAQIGRNRLPEHRDRKRMPYTLAFIDEVQRFATLAPFAVLHRCTRDVEFMGYDISSDDLIMTNLYGIHHDPELWSSPEAFQPERFLAVDTG---EYQPNEHLVPFGVGKRACLGESLARQELFLFIAGILQQHSARLHPD-SVKNLEDIKIGSDGIVHAPGAHRIIFSAR 519          
BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Match: A0A267F088 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002295g2 PE=3 SV=1)

HSP 1 Score: 243.047 bits (619), Expect = 3.101e-71
Identity = 143/394 (36.29%), Postives = 208/394 (52.79%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRF-TRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSD---WKRFVKIQDYFA-EEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            +G +W   R F LKVLRDFG  ++ + E I  E   L   LD   D++V      P    N+IS  + N R  T+D+    F+  + +NL  N +I   I   FP L       RLL L   D   +KR +++   F  ++I  HR  L   SE  D +D FL++Q  L     +  SF D+QL+R   EL IAG +TTS T+ W  L+ + +P+ Q+++  E+    G  RLP   DKKA+++T A +DEV R S++AP  + HR   D    G+ I  + LI  NLY  H DPE+W+ P  F PE F+    N   +Y+  E L+PFS+GKR CLGESLAR E F+F   + Q +++   ++  +D      +G+ GL+        +F RR
Sbjct:  130 EGELWREHRRFALKVLRDFGFARSGTEEAIHAELAELQQTLDAEPDELV------PRAIANVISVLLFNYRAGTQDEGFTDFMLASQENLQGN-NIGRFIPTAFPGLYSIPGFMRLLQLIGVDVFVFKRNIEVTHRFCRDQIDRHRRNLAEVSEPADFLDAFLLEQQRLNSKRSD-HSFDDFQLVRTLTELFIAGTDTTSNTIRWALLYAALHPECQDRIAAEVEAATGNSRLPVYRDKKAMHFTMAFIDEVQRYSTLAPFSVGHRCTRDIRFKGYDISSNDLIMVNLYGVHHDPELWDQPEQFRPERFI----NSSGEYETSEFLVPFSIGKRACLGESLARQELFLFLSGIFQAYRVELHKDCYKD-LKDIEVGSAGLVHAPGKHQIIFHRR 510          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Match: cyp2n13 (cytochrome P450 2J6-like [Source:NCBI gene;Acc:103035066])

HSP 1 Score: 216.083 bits (549), Expect = 1.750e-64
Identity = 133/373 (35.66%), Postives = 206/373 (55.23%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEI-IQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWK-TMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIG 1124
            +G++W  QR F L  LR+FGLGK K++E+ I  E   LLDE+D    Q  D S  F    +NII + +  +R+   D + Q + K T + +     I+  +   FP +    +  R   +F +    +  I ++  + + +H+  LD  S   D MD FLI   E + S    + F D  L+R +L+L +AG ETT+T+L W  ++++K P+IQ+KV +EI  +IG+ R P M DK  + YT+AV+ E+LR   + P+        D  + G+ IPK + I P L++   D + WE+P +F P+HF  LD  G  K+  R+  + FS GKR CLGE LAR E F+FF  + Q+F+  F E   E+  ++ I+G
Sbjct:  125 NGNLWKKQRRFALSTLRNFGLGK-KTMELAICEESHFLLDEMDRHKGQAFDPSGLFNNAVSNIICQLVFGQRYDYADYDFQQMLKYTSEAIHLEGSIWGRLYESFPNI-MKHLPGRHNVIFSN----YEHISEFIKKNLDKHKANLD-PSNPRDYMDSFLI---EKENSHDPADGFSDKNLVRCTLDLFLAGTETTTTSLGWALIYLAKNPEIQDKVQEEIDRVIGQSRQPGMADKPNMPYTEAVIHEILRRGDIVPLSGPRVAAKDTTLGGYAIPKGTTIMPILHSVLFDEDEWETPNSFNPQHF--LDKEG--KFVRRDAFLAFSAGKRVCLGEQLARMELFLFFTCLFQKFR--FSEVEGEELDTEGILG 481          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000007184.2 (cytochrome P450 2B4-like [Source:NCBI gene;Acc:103031531])

HSP 1 Score: 209.149 bits (531), Expect = 9.062e-62
Identity = 124/400 (31.00%), Postives = 213/400 (53.25%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIY-----TTNIISRFIMNKRFTRDDPNIQFIWKTMD-----NLAKNKDIFHLILLM--FPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            G+ W  QR F L  LRDFGLGK    E +  E   L+ E+     +      F+PI+      +NII   +   RF  DD     + + ++     + +    IF+L+ ++  FP   Q              W     ++ + +EE+++HR +LD      D +D +L++ +  KQ +    +F +  ++R++ +L IAG ETT+ TL W  ++M ++PD+QE+ H+EI  ++G +R P+M+D+  L YT A + E+ R +++ P+G++H+T     + G++IP  + I  NL A   D + W+ P TF PE+F  LD  G  ++   +  +PFS+G R CLGE+LAR+E FIFF S++Q+ + S+ +          +    GL+R++   N + + R
Sbjct:  126 GNSWRQQRRFALHTLRDFGLGKKSVEERVAEEAHFLIKEMLKQEGK-----AFYPIHPIMNSVSNIICSIVFGDRFEYDDRRFAKLLEIINENIRFSGSPVAQIFNLVPIIKYFPGPHQKI------------WHNLQSLRKFMSEEVEKHRKSLD-PENLRDFIDAYLVEMN--KQESNEDSTFHEENMLRSTTDLFIAGTETTANTLRWGLIYMMEHPDVQERCHEEIVRVLGFDRFPSMDDRAQLPYTHATVHEIQRYANIVPLGVVHQTTQPTKLRGYHIPAGTNIMSNLTAILTDKDHWKYPDTFNPENF--LDEKG--QFCKNDSFLPFSLGPRVCLGETLARTELFIFFTSLIQQLKFSWPQGAPPPNMDGVV----GLVRSNLPFNTICRSR 497          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000030554.1 (cytochrome P450 2B4-like [Source:NCBI gene;Acc:103029841])

HSP 1 Score: 209.149 bits (531), Expect = 9.188e-62
Identity = 122/370 (32.97%), Postives = 197/370 (53.24%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIY--TTNIISRFIMNKRFTRDD-----------PNIQFIWKTMDNLAKNKDIFHLILLM--FPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISF 1079
            G+ W  QR F L  LRDFGLGK    E +  E   L+ E+     +   F    PI    +NII   +   RF  DD            NI+F+   +        +F+LI  +  F    Q F            W     ++ +  EE++EH+  LD      D +D +L++   +KQ      +F +  ++R++++L IAG ETT+ TL W  ++M  +PD+QE+ H+EI  ++G +R P+M+D+  L YT A + E+ R +++ P+G++H T     + G+++P+ +++ PNL A   D + W+ P TF PE+F  LD  G  ++   +  +PFS+G R CLGE+LAR+E FIFF S++QR + S+
Sbjct:  126 GNSWRQQRRFALHTLRDFGLGKKSVEERVAEEARYLIKEM--LKQEGKAFYPSHPIMNSVSNIICSIVFGDRFEYDDRRFAKLLEIINENIRFLGSPVS------QVFNLIPFIKHFRGPHQKF------------WHNVHSLKKFIFEEMEEHKKTLD-PENLRDFIDAYLVEM--IKQEANEDSTFHEENMVRSTIDLFIAGTETTANTLRWGLIYMMDHPDVQERCHEEIVRVLGFDRFPSMDDRAKLPYTLATVHEIQRYANIVPLGVLHETTQATKLRGYHLPQGTIVMPNLTAIMADKDHWKYPNTFNPENF--LDEKG--QFCKNDSFLPFSLGPRVCLGETLARTELFIFFTSLIQRLKFSW 468          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000019474.2 (cytochrome P450 2K1-like [Source:NCBI gene;Acc:103034280])

HSP 1 Score: 208.379 bits (529), Expect = 1.589e-61
Identity = 131/376 (34.84%), Postives = 206/376 (54.79%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNI-QFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQT-IIG 1124
            +F +G  W   R F L  LRDFG+GK  S E I  E   L +  ++F  +  D ++      +NIIS  +   RF   DP   + + +  +N+        L+  MFP   +   +  +  LFV++ K  V+I+    E +K  +  L+ T E    +D FL+++ ++ +S      F +  LI     L +AG +T+ TTL W  L M+K P IQ++VH+EI  +IG  ++  + D+K+L YT AV+ E+ R +++ PM L H T  D + NGF+I K + ++P L +   D   WESP TF P+HF  LD  G  ++  ++  +PFS G+R CLGESLAR E F+FF S++Q F+ +    ++ED+   T +IG
Sbjct:  125 LFSNGENWREMRRFALSNLRDFGMGKRGSEEKIIEEIQYLKEVFESFGGKAFDTTQPVNNAVSNIISSIVYGSRFEYSDPQFKEMVNRANENVRIGGSASVLVYNMFPWTGR--FLRSVQKLFVNNEKNRVQIR----ELVKGLQETLN-TEERRGFVDSFLLRK-QIDESNEKASYFNEKNLIVTVGNLFVAGTDTSGTTLRWGLLLMAKNPHIQDRVHEEIDRVIGGRQV-VVEDRKSLPYTDAVIHEIQRCANIVPMSLPHVTSCDVHFNGFFIKKGTTVYPLLTSVLRDESEWESPRTFNPDHF--LDKQG--QFLKKDAFMPFSAGRRVCLGESLARMELFLFFTSLLQHFRFTPPPGLTEDQLDLTPVIG 487          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000052034.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000046.1:5870600:5884237:1 gene:ENSAMXG00000018921.2 transcript:ENSAMXT00000052034.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 204.912 bits (520), Expect = 1.719e-60
Identity = 124/377 (32.89%), Postives = 198/377 (52.52%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNI-QFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGED---LMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTII 1121
            +F +G  W   R F L  LRDFG+GK  S E I  E   +++E   F  +  D ++      +NIIS  +   RF   DP   + + +  +N+         +  +FP +            F+   ++  +  +   +EI    ++L  T   +D    +D FL+++   ++S      F D  L+   L L +AG +TT TTL W  L M+K P IQ++VH+EI  +IG  ++  + D+K+L YT AV+ E+ R +++ PM L H T  D + NGF+I K + ++P L +   D   WESP TF P+HF  LD  G  ++  ++  +PFS G+R CLGESLAR E F+FF S++Q F+ +    +S+D+   T +
Sbjct:   98 LFSNGENWREMRRFALTNLRDFGMGKRGSEEKIVEEIQYIVEEFGKFEGKAFDTTQPVNNAVSNIISSIVYGSRFEYSDPQFKEMVNRANENVRIGGSAPIRLYNVFPWIGP----------FLKSKRKLERNTEKNRKEINGIISSLQETLHPDDRRGFIDSFLVRKQSDEKSGQKNSRFNDKNLLSTVLNLFVAGTDTTGTTLRWGLLLMAKNPHIQDRVHEEIDRVIGGRQV-VVEDRKSLPYTDAVIHEIQRCANIVPMSLPHVTSCDVHFNGFFIKKGTTVYPLLTSVLRDESEWESPQTFNPDHF--LDKQG--RFAKKDAFMPFSAGRRVCLGESLARMELFLFFTSLLQHFRFTPPPGVSKDQLDLTPV 459          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011205.1 (pep scaffold:Pmarinus_7.0:GL477378:108537:110066:1 gene:ENSPMAG00000010178.1 transcript:ENSPMAT00000011205.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 186.808 bits (473), Expect = 5.511e-54
Identity = 119/363 (32.78%), Postives = 188/363 (51.79%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTT--NIISRFIMNKRFTRDDPNIQ-FIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEIS 1094
            G  W   R F L  LR+FGLGK+   + IQ E   L++    F  +   F   + + +   NII   +  KR+   D   Q F+    +NL     +   +  +FP L       +++F  ++  K+F++       +I   R+A     +   L+D +L    +L++      SF +  LI  +L+L IAG ETTSTTL W  L+M  +P+IQ + H+EI +I+G +RLP M D+ +L Y  AV+ E+ R S++ P G  H T  D     + IPK ++I  N+ +   D   W++P  F PE+FL  D     K+   +  +PFS G R CLGE+LA+ E F+FF S++Q F+  + + +S
Sbjct:  140 GKYWMQHRRFTLSTLRNFGLGKSSIEQTIQAEVGFLIE---AFKQKGSAFDPHYDLNSAVGNIICSMVKGKRYEYSDKQFQDFLHLVENNLQLQSGLLGTLCNIFPFLMDFPGPQQIIFKSMAKSKQFIR-------DIISERHATRDPIKPMCLIDAYL---SQLEKEDNPNSSFSEQSLIMLALDLFIAGAETTSTTLRWGLLYMMMHPEIQAQCHEEIDKIVGSDRLPCMEDRHSLPYLDAVIHEIQRFSNIVPFGAPHATTADVKFRQYLIPKGTIIMVNMKSVLSDENHWKTPYEFSPENFLDED----GKFVKPDAFLPFSAGPRVCLGENLAKMELFLFFASLLQHFEFYWPDLVS 485          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011254.1 (pep scaffold:Pmarinus_7.0:GL479221:5463:6953:-1 gene:ENSPMAG00000010227.1 transcript:ENSPMAT00000011254.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 184.496 bits (467), Expect = 3.582e-53
Identity = 121/367 (32.97%), Postives = 178/367 (48.50%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTT--NIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILL-MFPCLDQSFIVARLLFLFVSDWKRFV----KIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEIS 1094
            G  W  QR F L  LR+FG GKA   + I  E   L++   TF  +   F     +     NII   +   R+  D+   Q +   ++ L + +    +IL  +FP           L      W++      K+Q    + + EHR   D      DL+D +L +  + K +  +  SF    LI+  +EL I G ETTS TL W  LFM   PDIQ + H EI  ++G ER P M D+++L Y  AV+ E+ R  +V P+G++H T  D   N +  PK + +  NL +   D   W++P  F P+HFL  D   I      +  +PFS G R CLGESLA+ E F+FF S++Q F+  +   +S
Sbjct:  127 GDPWKQQRRFALSTLRNFGFGKATIADKISIEAKYLIE---TFKQETSAFDPHLNLNNALGNIICCLLNRNRYDYDNEQFQKLTHLLEYLVQLQAEPLVILCNVFP----------FLLKLPGPWQKVFHIHSKLQCLLNDIVSEHRATKD-QHNPRDLIDSYLAQIDKEKDNPNS--SFTHQSLIQILIELFIGGLETTSNTLRWGLLFMMMNPDIQARCHGEIDRVVGSERPPCMTDRRSLPYLDAVIHEIQRFGNVLPLGVLHATSKDVQFNDYLFPKGTHVMVNLMSALHDDIHWKTPNKFNPDHFLDKDGQCIQS----DAFLPFSAGPRVCLGESLAKMEIFLFFTSLLQHFEFYWPNSVS 473          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002462.1 (pep scaffold:Pmarinus_7.0:GL485824:2571:10389:-1 gene:ENSPMAG00000002249.1 transcript:ENSPMAT00000002462.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 174.096 bits (440), Expect = 7.174e-51
Identity = 110/322 (34.16%), Postives = 169/322 (52.48%), Query Frame = 3
Query:  189 TNIISRFIMNKRFTRDDPNIQFIWKT-MDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVES-FVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQ-EKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRT 1145
            +NII   +   RF  DD   + +     +N          I +  P L+      +L+F      +   K+  +F E I+EHR   +   +  DL+D +L    E+++ + + ES F D  L+    +L IAG ET+STTL W  L+M  YP IQ E+  +EI E+IG +R P   D+  L YT AV+ E  R+++VAP+G++H T  D    G+ IPK + +  NL +   D   W++P  F P+HF  LD+ G  ++   +  + FS G R CLGE+LAR E F+FF S++QRF+  + +  S   +    +  EGL R 
Sbjct:   15 SNIICSIVFGNRFDYDDKRFRNLLHLFAENFRIEGGWRGKICIFMPWLEDWPGPHQLIF------RNADKVNLFFQERIREHRQTRE-AGQPRDLIDAYL---DEMEKESQDPESTFTDGNLLNVVGDLFIAGTETSSTTLRWALLYMMAYPQIQAERCQREIDEVIGGDRSPNTTDRANLPYTDAVIHEAQRMANVAPLGVLHSTTTDVKFRGYNIPKGTKVLLNLTSVLHDETQWKTPNEFNPDHF--LDNTG--QFVKPDAFLAFSAGPRVCLGENLARMELFLFFTSLLQRFKFHWPDATSRPNF----VAAEGLSRA 318          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011204.1 (pep scaffold:Pmarinus_7.0:GL477378:78074:79555:1 gene:ENSPMAG00000010177.1 transcript:ENSPMAT00000011204.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 167.162 bits (422), Expect = 7.482e-47
Identity = 116/359 (32.31%), Postives = 175/359 (48.75%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTT--NIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILL-MFPCLDQSFIVARLLFLFVSDWKRF----VKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQ 1070
            G  W  QR F L  LR+FG GKA   + I  E   L++   TF  +  +F   F + +   NII   +   R+  ++   Q +   +++L + +    +IL  +FP           L      W++      K+Q    + + EHR   D      DL+D +L   H  K+      SF D  LI   +EL I G ETTS TL W  LFM   PDIQ + H+EI +++G +R P M D+++L Y  AV+ E+ R  ++ P G++H T  D   N +  PK + +  NL +   D   W++P  F P++FL  D   I      +  +PF  G   C GESLA+ E F+FF S++Q F+
Sbjct:  123 GDTWKQQRGFALSTLRNFGFGKATITDKISIEARYLIE---TFKQETSEFDPKFILNSAVGNIICSLLNGIRYDYNNEQFQKLTHLLEHLVQLQAEPLVILCNVFP----------FLIKLPGPWQKVFHIHTKLQCLLKDIVSEHRATKD-QHNPRDLIDSYL--AHIDKEKDNPNRSFTDQTLILLLIELFIGGMETTSNTLCWGLLFMMMNPDIQARCHEEIDKVVGSQRPPCMKDRRSLPYLDAVIHEIQRFGNILPFGVLHPTSKDVQFNEYVFPKGTHVMVNLMSAFYDDIHWKTPHKFNPDNFLDKDGQCIKS----DAFLPFPAGPCVCFGESLAKMELFLFFTSLLQHFE 461          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Match: cyp2u1 (cytochrome P450, family 2, subfamily U, polypeptide 1 [Source:ZFIN;Acc:ZDB-GENE-070730-1])

HSP 1 Score: 161.384 bits (407), Expect = 1.981e-46
Identity = 97/275 (35.27%), Postives = 145/275 (52.73%), Query Frame = 3
Query:  351 RLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQH--------ELKQSTGNVESFVDWQ-LIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDAN--INGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTII--GNEGL 1136
            R LF  V +  RF+K        I+EH   LD  +   D +D FL++ H           ++ G     +D   L     +L IAG +TT+ TL WC L M  YP +Q +V  E+  ++G+ R  +++D+  L  T A + EV RLSSV P+ + H         + GF IP+ S++  NL+ACH+DP +W  P  F PE F  LD +G  + + R+  +PF +G+R CLGESLAR E F+FF +++Q F  +     S D   ++ +  G  GL
Sbjct:   32 RELFSTVDEVSRFLK-----KGIIREHEETLD-PANPRDFIDAFLVESHGGHDDDEEGGGEAPGGTRGVLDADDLFYIVADLFIAGTDTTANTLLWCLLLMCTYPAVQARVQAELDAVVGRGRRVSLSDRPRLPLTVATIMEVQRLSSVVPLAIPHSATRSVRTELRGFTIPRGSVVLLNLWACHVDPRVWARPLLFDPERF--LDPHG--RLRRRDAFMPFGIGRRSCLGESLARVELFLFFSALMQEFTFTSSAPHSPDSAPRSPVLQGTFGL 296          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Yeast
Match: DIT2 (N-formyltyrosine oxidase; sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively [Source:SGD;Acc:S000002810])

HSP 1 Score: 61.2326 bits (147), Expect = 1.148e-10
Identity = 76/283 (26.86%), Postives = 120/283 (42.40%), Query Frame = 3
Query:  288 KDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDW-QLIRNSLELIIAGYETTSTTLNWCCLFMSKYPD-IQEKVHKEISEII---GKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMG-LIHRTFDDANING--FYIPKDSLIFPNLYACHMDPEIWESPTT-FYPEHFLSLDSNGISK----YQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISE 1097
            K IFH   L FP LD   I +R        +K  V  ++   + +++     ++  E        LI+ H            +D+ QL  N + +++AG+E      N     ++KY +  QEK+ KE++ I    G   LP +N         A + EV+R+    P+  +I+R        G    IPK   +  N +    DP+ W +    F PE + S D   I K     + R  +  F  G+R CLGE LA +E  I    M+++F+ S   E  E
Sbjct:  210 KQIFHPFFLTFPFLDVLPIPSR-----KKAFKDVVSFRELLVKRVQDEL-VNNYKFEQTTFAASDLIRAHN--------NEIIDYKQLTDNIVIILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGITDPKGLADLPLLN---------AFLFEVVRM--YPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGS-DIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEE 466          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Yeast
Match: ERG5 (C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs [Source:SGD;Acc:S000004617])

HSP 1 Score: 56.225 bits (134), Expect = 5.833e-9
Identity = 50/237 (21.10%), Postives = 101/237 (42.62%), Query Frame = 3
Query:  390 VKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGN-----VESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDK--KALNYTQAVMDEVLRLSSVAPMG--LIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQI 1073
            +KI +  A+  K+H  A     +   +MD +    H+ K S  +        F + ++       + A  + +S+   W    ++  PD+  K+ +E   +   +    +N    + + YT  V+ E LR      M   ++ + F  +    +  PK +++ P LY    DPE++E+P  F PE ++     G    + ++  + F  G   CLG++       I F +++ +F +
Sbjct:  272 MKIFENCAQMAKDHIAA---GGKPVCVMDAWCKLMHDAKNSNDDDSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSP--NYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWV----EGSKASEAKKNWLVFGCGPHVCLGQTYV----MITFAALLGKFAL 495          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Yeast
Match: ERG11 (Lanosterol 14-alpha-demethylase; catalyzes C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in ergosterol biosynthesis pathway; transcriptionally down-regulated when ergosterol is in excess; member of cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p; human CYP51A1 functionally complements the lethality of the erg11 null mutation [Source:SGD;Acc:S000001049])

HSP 1 Score: 46.2098 bits (108), Expect = 7.397e-6
Identity = 48/251 (19.12%), Postives = 101/251 (40.24%), Query Frame = 3
Query:  396 IQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEII--GKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPE-HFLSL---DSNGISKYQPREEL---------------IPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGE 1085
            I   +   IKE R       +  D+ DR LI       +  +     D ++    + +++ G  T++ T  W  L +++ PD+Q+++++E   ++  GK+ L T +  + +      + E LR+        +H  F    +   ++P  S + P  Y   + P        ++P  H  ++   + +  S Y   EE+               +PF  G+ +C+GE  A  +  +     ++  +  + E
Sbjct:  261 ISGTYMSLIKERR-------KNNDIQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKEL-TYDLLQEMPLLNQTIKETLRMHHP-----LHSLFRKV-MKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPE 497          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Match: EDO48207 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK94])

HSP 1 Score: 180.644 bits (457), Expect = 1.213e-51
Identity = 110/357 (30.81%), Postives = 184/357 (51.54%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKI--QDYFAEEIKEHRNALDFTSEG-EDLMDRFL-IKQHELKQSTGNVESFVDWQLIRNSLE-LIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQ 1070
            G  W + R      ++ +G  + +  ++I++E L L + L++ + +  D ++   I  TN+I   +   R+  DDP    +++  D L++     +L+  +FP L         +  F    +  ++I  + Y   E K   +   F  E   D  D  L  KQ   ++   + E   +  +I   L  L IAG ETTSTTL W  +++   PD+QE++HKEI ++IG++  P ++ +K L   +A   E LRL+++AP+ + H+  + + + GF IP+ + +F NL++ H DP +W+ P TF  + F  LD  G  K       +PF  G R CLGE LARSE F+F   M+QRF+
Sbjct:  116 GETWKLFRKLGHSTIKVYGENRLQ--DVIKDEVLELCNRLESSAGKPFDITQQSGIAVTNVICTKLFGTRYQIDDPEFLRVYEIHDKLSRIGFGGNLVTNIFPSLAS-------ILPFSEKQRDLIQIGQERYEILERKYQEHVKTFDPENIRDYTDALLKAKQDAEQEDKSSKEHLQESTIIMAGLATLFIAGSETTSTTLGWAVIYLLHNPDVQERLHKEIDDVIGRDAFPQLSKRKELPVLEAFTAETLRLANLAPLAIPHKARERSTLQGFEIPEGTTVFANLWSLHHDPTVWKDPFTFNLDRF--LDEEGKFKAPVGGTFLPFGAGPRVCLGEVLARSELFLFLSRMLQRFE 461          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Match: EDO46605 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPN7])

HSP 1 Score: 164.466 bits (415), Expect = 8.900e-46
Identity = 114/362 (31.49%), Postives = 175/362 (48.34%), Query Frame = 3
Query:   24 WAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAK-----NKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAE-EIKEHRNALDFTSEGE--DLMDRFLIKQHELKQSTGNVESFV--DWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISF 1079
            W +QR  +   LR +G G      +I  E  NL D         VD      +   N+I   +  KR+  DD     I  T +++AK     N  I+   L  FP               V   K  V  +D   + +I EHR       EGE  DL D  L    + KQ   N  S +  D  LI  + ++ +AG+ETT+T L W  L+++ YP++Q ++H+E+ ++I   R P + D+K+L Y +A + EVLR+S V P+ +  +     NI G+ IP+++ ++ NL+A H D   W  P  F P  FL   +N  S Y     ++PF  G R C+GESLA+ E F+F   ++ RF+++ 
Sbjct:  122 WKLQRRVVHSALRMYGSGVRILEALILQEVDNLCDIFANSQGAPVDTKLPLTLSVMNVICALVFGKRYGLDDAEFTDIVATTESMAKLASPENPLIYMPWLRFFP------------LQVVKKMKETVTARDRLIQRKITEHRETY---KEGEIRDLTDALLKSLEDAKQEDNNAMSLLTEDHLLIAIN-DVFMAGFETTTTALRWIFLYVAAYPEVQARIHQELDDVISFGRDPLIADRKSLPYLEATILEVLRISPVFPL-IRRKARKQLNIGGYCIPEETFVYVNLWAIHHDEAEWVDPYKFRPSRFLE-GTNSASAY----SMLPFGAGVRVCVGESLAKMELFLFVSRLLHRFKLNL 461          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Match: EDO40300 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7U4])

HSP 1 Score: 162.925 bits (411), Expect = 3.338e-45
Identity = 109/361 (30.19%), Postives = 177/361 (49.03%), Query Frame = 3
Query:   15 GHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMD-----NLAKN--KDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFL-IKQHELKQSTGNVESFVDWQLIRNSL-ELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQ 1070
            G  W I R      ++ +G  + +  E+I  E   L   L+   ++ +D ++ F    TN+I   I   R+  +DP  Q ++   D     N+ +   K+ F  +    P   Q   +  L      D +RFV ++  +     EH    D  +   D  D  L  KQ   ++   + E F +  +I   L  L +AG ETT+TTL+W   ++   P +Q ++HKEI ++IGK+  P ++ +K +   +A   E  RLS++ P+ L H+T  D  + G+ I K + +F NL++ H DP IW+ P TF  + F  LD+ G  +       +PF  G R CLGE LARSE F+F  +++Q F+
Sbjct:   90 GERWRIFRKLGHSTIKVYGEDRLQ--EVINEEVSELCKRLEESDEKPIDITKQFGTAVTNVICTKIFGNRYDINDPEFQRLYYINDKSTRLNIGEGWLKEAFPFLKPFLPYSQQVKEIKEL------DQERFVIMRAKY----DEHVETFD-PNHIRDYTDALLKAKQEAEEEDKSSKEHFGEGPIIMAGLVTLFLAGSETTTTTLSWAIAYLLHNPGVQARLHKEIDQVIGKDVSPKLSQRKNIPVLEAFTAETQRLSNLVPLSLPHKTTSDCTLLGYEIAKGTTVFTNLWSLHHDPSIWKEPDTFNLDRF--LDAKGKFQAPVGGTFLPFGAGPRVCLGEVLARSELFLFLATLLQHFE 435          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Match: EDO30835 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZN0])

HSP 1 Score: 161.77 bits (408), Expect = 9.212e-45
Identity = 103/339 (30.38%), Postives = 175/339 (51.62%), Query Frame = 3
Query:  150 QIVDFSEFFPIY-----TTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFA-EEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSL-ELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIG--KERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLI 1139
            +++D + F P Y     T N++S       +  +DP  Q + +  D + ++   F+ IL +FP L        L F    D K     +  +A ++ + H ++ D +    DL D F+    E  +    VESF   + +   + E+ IAG ET STT+ W   +++ YP++Q ++H+++ ++IG  K ++ T+ D+  L Y +AV+ E LR+S+  P+ + H+   D  ING++IPKD+ +  NL+  H DP  W  P  F P  FL+ D   I      E+L+PF  G+R C GE +A+ E F+   ++ Q  Q  F  E+  D  S ++ G  G++
Sbjct:  137 KMLDGTAFDPHYLLNLVTLNVVSSITFGTDYKFEDPEFQHVLRLNDAVGRSFKAFN-ILDVFPFL------IHLPFSASKDLKCVCAERGKYAMDKARRHVDSYD-SDRIRDLTDGFIKGLAEAVKEDDKVESFFTTEHVAMVMSEMTIAGSETASTTMRWMLAYLAVYPEVQARLHQQLDDVIGRNKNKIITLKDRDRLPYVEAVIAETLRISTPGPLAIPHKATCDTTINGYFIPKDTTVIFNLWGVHHDPAEWADPHVFNPARFLNKDGKLIKS----EKLMPFGGGRRVCPGEKMAKMELFLMTATLFQHLQ--FMPEL--DGPSPSLEGAMGVV 459          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Match: EDO41284 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S507])

HSP 1 Score: 160.229 bits (404), Expect = 6.015e-44
Identity = 105/310 (33.87%), Postives = 170/310 (54.84%), Query Frame = 3
Query:  174 FPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSD---WKRFVKIQDYFAEEI-KEHRNALDFTSEG-EDLMDRFLIKQHEL----KQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHR-TFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQI 1073
            F +  TNIIS F++ K F  DDP+     +    +     +   IL  FP L         + L +S+   +K+ V+I+D   ++   EH++   F+ +   DL D FL  + E+    K++ G V    D  +     ++  AG ETTSTTL+W   ++  YP +Q ++  +I ++IG  R P + DK  L Y +A + EVLR+++VAPMGL H+ T ++  + G+ IPKD++I  NL+A H DP  W +P  F P+ F++ D  G  +   +   +PFS G+R C+GESLA+ E F+    ++Q+F +
Sbjct:  169 FSLLITNIISSFLLGKSFEPDDPDFLTTLE-FTRIGSQLPVSGSILDNFPFL---------VHLPISESRFYKKLVEIRDRLLDKFFLEHKST--FSEDCIRDLTDAFLKAKLEVEREDKKAIGEV---TDDHITMLMTDVYFAGLETTSTTLSWLAAYLINYPQVQTRLQTDIDDVIG-SRWPVLADKPNLPYMEATIAEVLRIATVAPMGLPHKATTNNVPLMGYNIPKDTIIVMNLWAIHHDPREWPNPDKFDPDRFINED--GKFEVPGQRSYLPFSAGRRVCVGESLAKIELFLVMTRLLQQFTL 460          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Match: ENSORLT00000020799.2 (cytochrome P450 2J6 [Source:NCBI gene;Acc:101155419])

HSP 1 Score: 229.565 bits (584), Expect = 2.290e-69
Identity = 140/364 (38.46%), Postives = 196/364 (53.85%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLE-IIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNK-----DIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQIS 1076
            +F +G  W  QR F L  LR FG GK KSLE +I NE  +  +EL  F  + +D         +NII   +   RF   D   + +    D   + +      +++   L+  CL       + +      W+   ++QD+  EE+KEH+ + D  S+  D +D +L +  + K   G+  +F +  LI   L+L +AG ETTSTTL W  L+M+KYP+IQEKV  EI ++IGK R P M D+  L YT AV+ EV R+ ++ P+ L H T  D  + GF IPK  LI PNL +   D + WE+P  F P HFL+ D     K+  R   IPFS GKR CLGE+LAR E F+FF S +Q F  S
Sbjct:  148 IFSNGANWTEQRRFALSTLRYFGFGK-KSLEPVILNEFAHCAEELKRFKGEPLDPHLIINNTVSNIICHLVFGHRFNYGDKKFKKLMLLFDRALQIEASIWAQLYNSFTLIMRCLPGPHKTLQHI------WR---EVQDFIGEELKEHKKSWD-PSDARDYIDFYLTEIQKTKGQEGS--TFDEENLIMCVLDLFVAGSETTSTTLRWAFLYMAKYPEIQEKVQAEIHKVIGKSRPPCMEDRAELPYTDAVIHEVQRIGNIVPLSLPHATNKDVQLGGFTIPKGVLIIPNLTSVLFDEKEWETPHAFNPGHFLNKD----GKFVKRGAFIPFSAGKRLCLGENLARMELFLFFTSFMQHFSFS 494          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Match: cyp2n13 (cytochrome P450 2J6 [Source:NCBI gene;Acc:101156965])

HSP 1 Score: 226.483 bits (576), Expect = 1.737e-68
Identity = 133/373 (35.66%), Postives = 200/373 (53.62%), Query Frame = 3
Query:    6 FKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAK-NKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISF--GEEISEDRYSQT 1115
            F +G  W  QR F L  LR FGLGK    + I  E  +L  +++         +  F    +NII + +M KRF  DD N Q + K +    +    I+ ++   FP L     +  L       ++ +  +QD+ A+EIK H+  LD  +   D +D F+I   E+++   +   F D  L   SL+L +AG ETTSTTL W  +++ K+PD+Q KV +EI  +IG+ RLP+M D+  L YT AV+ E+ R+ ++ P+  +     D  + G++IPK + + P L +   D   WE+P TF PEHFL  D     K+  +E  +PFS GKR CLGE LAR E F+F V ++Q+F  S   G E+S +  + T
Sbjct:  124 FSNGEKWKKQRRFALSTLRTFGLGKNTMEQSICEEIRHLQQQIENEKGGPFSPAGLFNNAVSNIICQLVMGKRFDYDDNNFQVMMKYISEAVQLEGSIWGILYESFPGL-----MKHLPGSHNKIFRNYKIVQDFLAQEIKIHKQDLD-PNNPRDYIDSFII---EMEKHQNSDLGFNDANLAFCSLDLFVAGTETTSTTLMWALIYLIKHPDVQVKVQQEIDRVIGQNRLPSMADRPNLPYTDAVVHEIQRIGNIVPLNGLRVAAKDTTLGGYFIPKGTALMPMLTSVLFDKTEWETPDTFNPEHFLDAD----GKFVKKEAFLPFSAGKRVCLGEGLARMELFLFLVGLLQKFSFSVPEGVELSTEGITGT 483          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Match: cyp2n13 (cytochrome P450 2J6 [Source:NCBI gene;Acc:101156566])

HSP 1 Score: 219.164 bits (557), Expect = 1.149e-65
Identity = 130/371 (35.04%), Postives = 200/371 (53.91%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAK-NKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISF--GEEISEDRYSQT 1115
            +G  W  QR F L  LR FGLGK    + I  E  +L  E+++   Q+   +  F    +NI+ + +M KRF  +D +   + K +  + +    ++ L+   FP L     +  L       +K F  ++D+  +EIK H+  LD  +   D +D FLI   E+++   +   F +  L   SL+L +AG ETTSTTL W  +++ K+PD+Q KV +EI  +IG+ RLP+M D+  L YT AV+ E+ R  ++ P+  +     D  + G++IPK + + P L +   D   WE+P TF PEHFL  D     K+  +E  +PFS GKR CLGE LAR E F+F V ++Q+F  S   G E+S +  + T
Sbjct:  126 NGEKWKKQRRFALSTLRTFGLGKNTMEQCICEEIRHLQAEIESEKGQLFTPTGLFNNAVSNIVCQLVMGKRFDYNDHDFHTMIKYLSEVLRLEGSVWGLLYEAFPGL-----MKHLPGPHNEMFKDFDILRDFLDQEIKMHKKDLD-RNNPRDYIDSFLI---EMEKHQNSDLGFNEANLAFCSLDLFLAGTETTSTTLMWALIYLIKHPDVQVKVQQEIDRVIGQNRLPSMADRPNLPYTDAVIHEIQRFGNIVPLNGLRVAAKDTTLGGYFIPKGTALMPMLTSVLFDKTEWETPDTFNPEHFLDAD----GKFVKKEAFLPFSAGKRVCLGEGLARMELFLFLVGLLQKFSFSVPEGVELSTEGITGT 483          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Match: ENSORLT00000018818.2 (cytochrome P450 2J2 [Source:NCBI gene;Acc:101157767])

HSP 1 Score: 217.238 bits (552), Expect = 6.217e-65
Identity = 141/397 (35.52%), Postives = 198/397 (49.87%), Query Frame = 3
Query:   12 DGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFH-LILLMFPCLDQSFIVA-RLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR*LCKMP 1196
            +G  W  QR F L  LR+FGLGK    + IQ EC  +         +  D         +NII   +  +RF   D   Q I + +  + K +  F  L   +FP L + F    + LF  V     FVKI+      I+EH+  LD     +D +D FLI   E++++ G    F    L   +L+L  AG ETT+TTL W  LFM  YPDIQE+VH EI  +IG  R P+M DK+ + YT AV+ E+ R+  + P+G+      D  ++ + IPK ++I P L+    D  +WE+P +F P+HFL+ D      ++ RE   PF  GKR CLGE LAR E F+FF S +QRF  S     +       + G  G IR+        K   LC +P
Sbjct:  127 NGIQWKHQRRFALHTLRNFGLGKKTMEKYIQEECHYITQAFAEHQGKPFDAQPLLNSAVSNIICCLVFGERFEYSDKEYQQILQDLTEVVKLQGSFSALAYNVFPWLMKRFPGPLQKLFTLVDKIMDFVKIK------IEEHKENLDPACP-KDYIDSFLI---EMEKNQGEDFGFDIKNLCACTLDLFGAGSETTTTTLYWGLLFMIHYPDIQEEVHAEIDAVIGSSRQPSMADKENMPYTDAVIHEIQRMGDIVPIGVARMASRDTMLDNYTIPKGTMIMPALHTVLHDESVWETPHSFNPQHFLNQDGT----FKKREAFFPFGAGKRVCLGEQLARMELFLFFTSFLQRFSFS-----TAGGEKPPLEGRMGTIRSP-------KSYRLCAVP 497          
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Match: ENSORLT00000019638.2 (cytochrome P450 2K1 [Source:NCBI gene;Acc:101157991])

HSP 1 Score: 213.772 bits (543), Expect = 1.784e-63
Identity = 132/381 (34.65%), Postives = 197/381 (51.71%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEG------EDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGN 1127
            ++ +G IW   R F L  LRDFG+GK    + I  EC  LL+    F     D ++      +NII   +   RF  DDP    +   +D   +N     + L   P L Q++ +   LF +V+  +   ++ +  A   K++++      E          +D FL+K   L++S     +F D  L+   + L  AG ETTSTTL W  L M+KYP IQ++V  E+  +IG +R+  ++D+K L +T AV+ E+ RL+S+ P  L H+T  D    G++I K + +FP L +   D   WE P TFYP HFL  D     K+  RE  IPFS G+R CLGESLAR E F+FF +++Q F  +    +S++  S T  G 
Sbjct:  124 LWSNGDIWRDIRRFALTNLRDFGMGKKACEDKITEECQYLLEVFKKFKGNAFDTTKPLNYAVSNIICSMVYGSRFEYDDPKFTSM---VDRTNRN-----IQLSGSPTL-QAYNMVPWLFKWVASRR---EVHECAAANRKQNQSIFSHLKETLNPQMCRGFVDAFLVKGQTLEKSGVTNSAFNDENLLMTVIHLFAAGTETTSTTLRWGLLLMAKYPKIQDQVQDELRRVIG-DRMVQVSDRKNLPFTDAVIHEIQRLASIVPTALPHKTSKDVTFQGYFIKKGTTVFPLLTSVLHDANEWEKPHTFYPAHFLDKD----GKFVKREAFIPFSAGRRICLGESLARMELFMFFTTLLQNFCFTPPPGVSKEELSLTPCGG 487          
BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Match: SMESG000078094.1 (SMESG000078094.1)

HSP 1 Score: 770 bits (1987), Expect = 0.000e+0
Identity = 372/392 (94.90%), Postives = 384/392 (97.96%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            MFKDG   A QRSF+LKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGED+MDRFLIKQHELKQSTGNVESFVDWQLIRNS+EL IAG+ETTSTTLNWCCLFMSKYPDIQEKV+KEISEIIGKERLPTMNDKKA+NYTQ+VMDEVLRLSSV+P+ LIHRTF DANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFV+MVQRFQISFGEEISE++Y QTIIGNEGLIRTSDIKNFLFKRR
Sbjct:  115 MFKDGQGLATQRSFILKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDIMDRFLIKQHELKQSTGNVESFVDWQLIRNSVELFIAGFETTSTTLNWCCLFMSKYPDIQEKVYKEISEIIGKERLPTMNDKKAMNYTQSVMDEVLRLSSVSPLSLIHRTFHDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVTMVQRFQISFGEEISEEKYLQTIIGNEGLIRTSDIKNFLFKRR 506          
BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Match: SMESG000078100.1 (SMESG000078100.1)

HSP 1 Score: 766.148 bits (1977), Expect = 0.000e+0
Identity = 372/392 (94.90%), Postives = 379/392 (96.68%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            MFKDG   A QRSF+LKVLRDFGLGK+KSLEIIQNECLNLLDELDT SDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVH+EISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGL+HRTF DANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQC+GESLARSEYFIFFVSMVQRFQISF EEISE++Y QTIIGNEG IRTSDI  F FK R
Sbjct:  115 MFKDGQGLATQRSFILKVLRDFGLGKSKSLEIIQNECLNLLDELDTLSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHEEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLMHRTFHDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCIGESLARSEYFIFFVSMVQRFQISFAEEISEEKYLQTIIGNEGHIRTSDITKFKFKNR 506          
BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Match: SMESG000078091.1 (SMESG000078091.1)

HSP 1 Score: 721.079 bits (1860), Expect = 0.000e+0
Identity = 345/392 (88.01%), Postives = 363/392 (92.60%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            +FKDG IWA QRSF+LKVLRDFGLGK+KS+EI+QNEC N LDELDT S QIVDFSE  PIYTTNIISRFIMNKRFTRDDPNIQ I +T++N  KNKDI  LILLMFPC D S ++ +L++L  S WK FVKIQ+YF EEI+EHR  LD TSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIR S+EL IAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISF EEISED+YSQTIIGNEG+IRTSDIKNFLFKRR
Sbjct:  115 IFKDGKIWATQRSFILKVLRDFGLGKSKSIEIVQNECFNFLDELDTLSGQIVDFSELIPIYTTNIISRFIMNKRFTRDDPNIQLIEETINNSTKNKDIIQLILLMFPCFDNSSLICQLIYLLTSKWKSFVKIQNYFGEEIEEHRTNLDLTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRTSVELFIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFAEEISEDKYSQTIIGNEGVIRTSDIKNFLFKRR 506          
BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Match: SMESG000078092.1 (SMESG000078092.1)

HSP 1 Score: 708.368 bits (1827), Expect = 0.000e+0
Identity = 336/392 (85.71%), Postives = 360/392 (91.84%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            ++KDG IWA QRSF+LKVLRDFGLGK+KS+EI+QNEC N LDELDT S QIVDFSE  PIYTTNIISRFIMNKRFTRDDPN+ F+ K +    KNKDIF LILLMFPC D S ++ +L++L  S+WK F++ QD+FA+EIKEHRNALDFTSEGEDLMDRFLIKQ++LKQSTGNVESFVDWQLIR S+EL IAG+ETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSV PM LIHRTF DANINGFYIPKDSLIFPNLYACHMDPEIWE P T YPEHFLSLDSNGISKYQPREELIPFSVGKRQC+GESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR
Sbjct:  115 IYKDGKIWATQRSFILKVLRDFGLGKSKSIEIVQNECFNFLDELDTLSGQIVDFSELIPIYTTNIISRFIMNKRFTRDDPNVHFMEKAITKFTKNKDIFQLILLMFPCFDNSSLICQLIYLLTSEWKSFIRTQDFFADEIKEHRNALDFTSEGEDLMDRFLIKQYQLKQSTGNVESFVDWQLIRTSVELFIAGFETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVVPMALIHRTFHDANINGFYIPKDSLIFPNLYACHMDPEIWEFPKTLYPEHFLSLDSNGISKYQPREELIPFSVGKRQCIGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 506          
BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Match: SMESG000078098.1 (SMESG000078098.1)

HSP 1 Score: 701.434 bits (1809), Expect = 0.000e+0
Identity = 338/392 (86.22%), Postives = 357/392 (91.07%), Query Frame = 3
Query:    3 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQIVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFHLILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR 1178
            MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLN LDELDT S QIV+FSE  PIYTTNIISRFIMNKRFTRDDP +QFI KT+ NL K+KDI  LIL+MFPC D S + ++L+FL  + WKRFV I++YF EEI+EHR  LD TSEGEDLMDRFLIKQ +LKQSTGNVESFVDWQLIRNS+E+ IAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSV PM LIHRTF DANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSN ISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISF EEISE++Y QTIIGNEG IRTSDI  F FK+R
Sbjct:  115 MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNFLDELDTLSGQIVEFSELIPIYTTNIISRFIMNKRFTRDDPKVQFIGKTITNLTKSKDILQLILIMFPCFDTSSLFSKLVFLLNTKWKRFVTIENYFWEEIEEHRTNLDLTSEGEDLMDRFLIKQRQLKQSTGNVESFVDWQLIRNSVEIFIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVVPMALIHRTFYDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNEISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFAEEISEEKYLQTIIGNEGHIRTSDITKFKFKKR 506          
The following BLAST results are available for this feature:
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CYP2J21.144e-6436.26cytochrome P450 family 2 subfamily J member 2 [Sou... [more]
CYP2B62.237e-6234.81cytochrome P450 family 2 subfamily B member 6 [Sou... [more]
CYP2U11.299e-5834.26cytochrome P450 family 2 subfamily U member 1 [Sou... [more]
CYP2R11.203e-5633.60cytochrome P450 family 2 subfamily R member 1 [Sou... [more]
CYP2D62.322e-5634.24cytochrome P450 family 2 subfamily D member 6 [Sou... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cyp-33C72.848e-5532.97CYtochrome P450 family [Source:UniProtKB/TrEMBL;A... [more]
cyp-33C51.464e-5432.22CYtochrome P450 family [Source:UniProtKB/TrEMBL;A... [more]
cyp-33A15.299e-5433.43CYtochrome P450 family [Source:UniProtKB/TrEMBL;A... [more]
cyp-33E15.810e-5433.24CYtochrome P450 family [Source:UniProtKB/TrEMBL;A... [more]
cyp-33E15.810e-5433.24CYtochrome P450 family [Source:UniProtKB/TrEMBL;A... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cyp18a11.695e-5130.10gene:FBgn0010383 transcript:FBtr0074610[more]
Cyp18a11.695e-5130.10gene:FBgn0010383 transcript:FBtr0074609[more]
Cyp303a18.926e-4428.03gene:FBgn0001992 transcript:FBtr0343812[more]
Cyp303a18.926e-4428.03gene:FBgn0001992 transcript:FBtr0080828[more]
Cyp305a12.937e-4228.61gene:FBgn0036910 transcript:FBtr0074925[more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cyp2y31.056e-6538.06cytochrome P450, family 2, subfamily Y, polypeptid... [more]
cyp2y39.882e-6537.78cytochrome P450, family 2, subfamily Y, polypeptid... [more]
cyp2k199.296e-6333.42cytochrome P450, family 2, subfamily k, polypeptid... [more]
cyp2k217.713e-6233.95cytochrome P450, family 2, subfamily k, polypeptid... [more]
cyp2p82.111e-6136.67cytochrome P450, family 2, subfamily P, polypeptid... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cyp11a11.749e-6336.01cytochrome P450 family 11 subfamily A member 1 [So... [more]
cyp11a14.274e-6335.73cytochrome P450 family 11 subfamily A member 1 [So... [more]
cyp11a12.577e-6235.73cytochrome P450 family 11 subfamily A member 1 [So... [more]
cyp11a17.396e-6235.25cytochrome P450 family 11 subfamily A member 1 [So... [more]
ENSXETT00000056215.11.639e-6136.26cytochrome P450 2D20-like [Source:NCBI gene;Acc:10... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cyp2j135.728e-6838.12cytochrome P450, family 2, subfamily j, polypeptid... [more]
Cyp2b196.131e-6635.25cytochrome P450, family 2, subfamily b, polypeptid... [more]
Cyp2j61.756e-6535.73cytochrome P450, family 2, subfamily j, polypeptid... [more]
Cyp2b92.872e-6435.07cytochrome P450, family 2, subfamily b, polypeptid... [more]
Cyp2d123.197e-6436.80cytochrome P450, family 2, subfamily d, polypeptid... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q27712|CP2L1_PANAR1.098e-6633.85Cytochrome P450 2L1 OS=Panulirus argus OX=6737 GN=... [more]
sp|O55071|CP2BJ_MOUSE4.289e-6535.25Cytochrome P450 2B19 OS=Mus musculus OX=10090 GN=C... [more]
sp|O54750|CP2J6_MOUSE1.229e-6435.73Cytochrome P450 2J6 OS=Mus musculus OX=10090 GN=Cy... [more]
sp|P51589|CP2J2_HUMAN5.495e-6436.26Cytochrome P450 2J2 OS=Homo sapiens OX=9606 GN=CYP... [more]
sp|P24460|CP2BB_CANLF5.588e-6435.25Cytochrome P450 2B11 OS=Canis lupus familiaris OX=... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4P8NYX51.684e-17261.99P450 2B-like protein OS=Dugesia japonica OX=6161 G... [more]
A0A2U8U4739.767e-16759.23Cytochrome P450 2K1-like protein OS=Dugesia japoni... [more]
A0A1I8I1X16.673e-7537.31Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8HTI61.010e-7437.31Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267F0883.101e-7136.29Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cyp2n131.750e-6435.66cytochrome P450 2J6-like [Source:NCBI gene;Acc:103... [more]
ENSAMXT00000007184.29.062e-6231.00cytochrome P450 2B4-like [Source:NCBI gene;Acc:103... [more]
ENSAMXT00000030554.19.188e-6232.97cytochrome P450 2B4-like [Source:NCBI gene;Acc:103... [more]
ENSAMXT00000019474.21.589e-6134.84cytochrome P450 2K1-like [Source:NCBI gene;Acc:103... [more]
ENSAMXT00000052034.11.719e-6032.89pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000011205.15.511e-5432.78pep scaffold:Pmarinus_7.0:GL477378:108537:110066:1... [more]
ENSPMAT00000011254.13.582e-5332.97pep scaffold:Pmarinus_7.0:GL479221:5463:6953:-1 ge... [more]
ENSPMAT00000002462.17.174e-5134.16pep scaffold:Pmarinus_7.0:GL485824:2571:10389:-1 g... [more]
ENSPMAT00000011204.17.482e-4732.31pep scaffold:Pmarinus_7.0:GL477378:78074:79555:1 g... [more]
cyp2u11.981e-4635.27cytochrome P450, family 2, subfamily U, polypeptid... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
DIT21.148e-1026.86N-formyltyrosine oxidase; sporulation-specific mic... [more]
ERG55.833e-921.10C-22 sterol desaturase; a cytochrome P450 enzyme t... [more]
ERG117.397e-619.12Lanosterol 14-alpha-demethylase; catalyzes C-14 de... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO482071.213e-5130.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO466058.900e-4631.49Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO403003.338e-4530.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO308359.212e-4530.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO412846.015e-4433.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000020799.22.290e-6938.46cytochrome P450 2J6 [Source:NCBI gene;Acc:10115541... [more]
cyp2n131.737e-6835.66cytochrome P450 2J6 [Source:NCBI gene;Acc:10115696... [more]
cyp2n131.149e-6535.04cytochrome P450 2J6 [Source:NCBI gene;Acc:10115656... [more]
ENSORLT00000018818.26.217e-6535.52cytochrome P450 2J2 [Source:NCBI gene;Acc:10115776... [more]
ENSORLT00000019638.21.784e-6334.65cytochrome P450 2K1 [Source:NCBI gene;Acc:10115799... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000078094.10.000e+094.90SMESG000078094.1[more]
SMESG000078100.10.000e+094.90SMESG000078100.1[more]
SMESG000078091.10.000e+088.01SMESG000078091.1[more]
SMESG000078092.10.000e+085.71SMESG000078092.1[more]
SMESG000078098.10.000e+086.22SMESG000078098.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30021752 ID=SMED30021752|Name=Cytochrome P450 2K1-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1325bp
TAATGTTCAAAGATGGTCATATATGGGCTATTCAAAGATCCTTTCTCCTC
AAAGTTCTCCGAGACTTTGGATTGGGAAAAGCTAAATCTTTAGAAATTAT
TCAAAATGAGTGTTTAAACCTTTTAGATGAACTTGATACTTTTTCTGATC
AAATTGTAGATTTCTCCGAATTTTTCCCAATATATACAACAAACATTATT
TCTAGATTCATCATGAATAAAAGATTCACCAGAGATGATCCGAATATTCA
ATTCATTTGGAAAACCATGGATAATTTGGCTAAAAATAAAGATATATTTC
ATTTAATATTATTAATGTTTCCGTGTCTCGATCAATCATTTATTGTCGCT
AGACTCCTTTTCTTATTTGTTTCAGATTGGAAACGTTTTGTCAAGATTCA
AGATTATTTTGCGGAGGAAATTAAAGAACATCGGAATGCTCTGGATTTTA
CTTCTGAAGGAGAAGATCTAATGGACCGTTTCTTAATCAAACAGCACGAA
TTGAAACAATCAACTGGGAATGTTGAAAGCTTTGTTGACTGGCAGTTGAT
TCGTAATTCCCTTGAACTAATTATCGCTGGCTATGAAACAACATCAACAA
CCCTCAATTGGTGTTGCCTTTTCATGTCGAAGTATCCTGATATCCAAGAG
AAAGTTCATAAAGAAATAAGCGAAATCATAGGAAAAGAACGCTTACCGAC
GATGAATGATAAGAAAGCACTGAATTATACACAAGCAGTCATGGATGAAG
TATTACGACTGAGCTCGGTCGCACCAATGGGTTTGATTCATAGAACGTTT
GATGATGCAAATATAAATGGATTTTACATTCCGAAAGATTCTCTAATCTT
TCCTAATTTATATGCTTGTCACATGGATCCGGAAATATGGGAATCTCCTA
CAACGTTTTATCCGGAACATTTCTTAAGTTTAGATAGCAATGGAATTTCA
AAATACCAACCGAGAGAGGAACTGATACCATTTAGTGTTGGGAAACGACA
ATGCCTTGGCGAGTCTCTTGCTAGATCAGAATACTTTATTTTCTTTGTAA
GCATGGTCCAACGATTCCAGATAAGCTTTGGAGAAGAAATTAGTGAAGAT
AGATATTCCCAAACAATAATTGGCAATGAAGGTCTCATTAGAACCTCCGA
TATTAAGAATTTCCTCTTCAAAAGACGATAATTATGTAAGATGCCACTCT
TTGTGTCAAATCTATCAATATAACATTAGATTTGGGTTCTTATAGCCACA
ATAATCATAAATATAATTTATTAGTGAAAAATATGTGATAAATTATTTAG
TCAATTAAATATAATTTAGTGCCAC
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protein sequence of SMED30021752-orf-1

>SMED30021752-orf-1 ID=SMED30021752-orf-1|Name=SMED30021752-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=393bp
MFKDGHIWAIQRSFLLKVLRDFGLGKAKSLEIIQNECLNLLDELDTFSDQ
IVDFSEFFPIYTTNIISRFIMNKRFTRDDPNIQFIWKTMDNLAKNKDIFH
LILLMFPCLDQSFIVARLLFLFVSDWKRFVKIQDYFAEEIKEHRNALDFT
SEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRNSLELIIAGYETTSTT
LNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEV
LRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPT
TFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVS
MVQRFQISFGEEISEDRYSQTIIGNEGLIRTSDIKNFLFKRR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0002142parenchyma
Vocabulary: INTERPRO
TermDefinition
IPR036396Cyt_P450_sf
IPR002401Cyt_P450_E_grp-I
IPR001128Cyt_P450
IPR017972Cyt_P450_CS
Vocabulary: molecular function
TermDefinition
GO:0020037heme binding
GO:0005506iron ion binding
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0004497monooxygenase activity
GO:0016491oxidoreductase activity
GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 30..50
NoneNo IPR availablePANTHERPTHR24300FAMILY NOT NAMEDcoord: 7..366
IPR001128Cytochrome P450PRINTSPR00385P450coord: 192..209
score: 39.94
coord: 325..334
score: 58.42
coord: 245..256
score: 40.78
coord: 334..345
score: 48.97
IPR001128Cytochrome P450PFAMPF00067p450coord: 2..366
e-value: 1.4E-81
score: 274.6
IPR002401Cytochrome P450, E-class, group IPRINTSPR00463EP450Icoord: 181..198
score: 35.42
coord: 324..334
score: 56.16
coord: 61..79
score: 28.27
coord: 285..309
score: 39.6
coord: 244..262
score: 36.34
coord: 201..227
score: 37.85
coord: 334..357
score: 41.7
IPR036396Cytochrome P450 superfamilyGENE3DG3DSA:1.10.630.10coord: 1..373
e-value: 4.7E-98
score: 331.1
IPR036396Cytochrome P450 superfamilySUPERFAMILYSSF48264Cytochrome P450coord: 4..364
IPR017972Cytochrome P450, conserved sitePROSITEPS00086CYTOCHROME_P450coord: 327..336