Forkhead F-1

Overview


Name	Forkhead F-1
Smed ID	SMED30021716
Length (bp)	2253

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Forkhead F-1 (SMED30021716) t-SNE clustered cells

Violin plots show distribution of expression levels for Forkhead F-1 (SMED30021716) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Forkhead F-1 (SMED30021716) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Forkhead F-1 (SMED30021716) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30021716

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
cephalic ganglia	SMED30021716	SMESG000066497.1	dd_Smed_v4_6910_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30021716	SMESG000066497.1	dd_Smed_v4_6910_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30021716	SMESG000066497.1	dd_Smed_v4_6910_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30021716	SMESG000066497.1	dd_Smed_v4_6910_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30021716	SMESG000066497.1	Contig42850	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30021716	SMESG000066497.1	Contig42850	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
enteric muscle cell	SMED30021716	SMESG000066497.1	dd_Smed_v4_6910_0_1	dd_Smed_v4	PMID:30471994 Scimone et al., 2018
pigment cell	SMED30021716	SMESG000066497.1	dd_Smed_v6_6910_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Forkhead F-1 vs. Ensembl Human
Match: FOXF1 (forkhead box F1 [Source:HGNC Symbol;Acc:HGNC:3809])

HSP 1 Score: 168.703 bits (426), Expect = 1.913e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   44 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 134

[Close]

BLAST of Forkhead F-1 vs. Ensembl Human
Match: FOXF2 (forkhead box F2 [Source:HGNC Symbol;Acc:HGNC:3810])

HSP 1 Score: 167.933 bits (424), Expect = 1.476e-44
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   96 RRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 186

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BLAST of Forkhead F-1 vs. Ensembl Human
Match: FOXI2 (forkhead box I2 [Source:HGNC Symbol;Acc:HGNC:32448])

HSP 1 Score: 116.701 bits (291), Expect = 6.587e-28
Identity = 50/87 (57.47%), Postives = 67/87 (77.01%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            +P  SY ALI MAIQ++P+RK TLS+IY Y+  NFPF++    GW+NS+RHNLSLN+CF K+P+    PGKG+YWT+DP  E MF++
Sbjct:  102 RPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDN 188

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BLAST of Forkhead F-1 vs. Ensembl Human
Match: FOXL1 (forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817])

HSP 1 Score: 115.931 bits (289), Expect = 2.045e-27
Identity = 50/87 (57.47%), Postives = 65/87 (74.71%), Query Frame = 1

Query:  946 EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            +KP  SYIALI MAIQ +P ++ TL+ IY ++   FPF+    QGW+NS+RHNLSLN+CF+K+P+  GRPGKG YWT+DP    MFE
Sbjct:   48 QKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFE 134

[Close]

BLAST of Forkhead F-1 vs. Ensembl Human
Match: FOXE1 (forkhead box E1 [Source:HGNC Symbol;Acc:HGNC:3806])

HSP 1 Score: 114.775 bits (286), Expect = 6.234e-27
Identity = 48/86 (55.81%), Postives = 65/86 (75.58%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            KP  SYIALI MAI  +P R+ TL  IY ++ + FPF++   + W+NS+RHNL+LN+CF+K+P+  GRPGKG+YW +DP AE MFE
Sbjct:   53 KPPYSYIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFE 138

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BLAST of Forkhead F-1 vs. Ensembl Celegans
Match: let-381 (pep chromosome:WBcel235:I:6320289:6324018:-1 gene:WBGene00002601.1 transcript:F26B1.7.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:let-381)

HSP 1 Score: 129.798 bits (325), Expect = 1.780e-32
Identity = 58/96 (60.42%), Postives = 72/96 (75.00%), Query Frame = 1

Query:  931 AKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMG---RPGKGHYWTIDPTAEFMFED 1209
            ++++ EKP  SYIALI MAI   P +K TL+EIY+YLQ+NF FF+G Y GW+NS+RHNLSLNECF+KLPK  G   R  KGH WTI  + EFM E+
Sbjct:   66 SRKRKEKPPFSYIALIAMAISKRPDKKATLAEIYSYLQENFEFFRGEYAGWRNSIRHNLSLNECFVKLPKDTGESYRGRKGHKWTISDSCEFMLEE 161

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BLAST of Forkhead F-1 vs. Ensembl Celegans
Match: fkh-2 (ForKHead transcription factor family [Source:UniProtKB/TrEMBL;Acc:Q95QA9])

HSP 1 Score: 108.227 bits (269), Expect = 7.657e-26
Identity = 46/83 (55.42%), Postives = 64/83 (77.11%), Query Frame = 1

Query:  946 EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAE 1194
            +KP  SY ALI+MAI+ SP ++ TL+ IY Y+  N+PF++   QGW+NS+RHNLSLN+CF+K+P+    PGKG+YW +D TAE
Sbjct:   92 DKPPFSYNALIMMAIKDSPEKRLTLAGIYEYIVTNYPFYRDNKQGWQNSIRHNLSLNKCFVKVPRNFDDPGKGNYWMLDATAE 174

[Close]

BLAST of Forkhead F-1 vs. Ensembl Celegans
Match: unc-130 (pep chromosome:WBcel235:II:11281986:11283953:1 gene:WBGene00006853.1 transcript:C47G2.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-130)

HSP 1 Score: 105.916 bits (263), Expect = 1.580e-24
Identity = 48/96 (50.00%), Postives = 67/96 (69.79%), Query Frame = 1

Query:  928 TAKRKS--EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            +  RKS   KP  SYIALI M+I  SP +K TLSEI  ++   F +++  +  W+NS+RHNLSLN+CF+K+ +G G PGKG+YW +DP  E MF++
Sbjct:  118 SGHRKSSHAKPPYSYIALIAMSILNSPEKKLTLSEICEFIINKFEYYKEKFPAWQNSIRHNLSLNDCFVKVARGPGNPGKGNYWALDPNCEDMFDN 213

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BLAST of Forkhead F-1 vs. Ensembl Celegans
Match: lin-31 (pep chromosome:WBcel235:II:3982549:3986944:1 gene:WBGene00003017.1 transcript:K10G6.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-31)

HSP 1 Score: 103.219 bits (256), Expect = 1.800e-24
Identity = 46/88 (52.27%), Postives = 59/88 (67.05%), Query Frame = 1

Query:  946 EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            +KP  SYI L  MAIQ S  +   L+EIY Y+   FPF++   Q W+NS+RHNLS N+CFIK+P+   RPGKG YW + P A  MFE+
Sbjct:   12 QKPPYSYIWLTYMAIQDSDDKMLPLTEIYKYIMDRFPFYRKNTQRWQNSLRHNLSFNDCFIKIPRRADRPGKGSYWAVHPNASGMFEN 99

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BLAST of Forkhead F-1 vs. Ensembl Celegans
Match: fkh-10 (ForKHead transcription factor family [Source:UniProtKB/TrEMBL;Acc:O17593])

HSP 1 Score: 98.2117 bits (243), Expect = 3.732e-23
Identity = 42/86 (48.84%), Postives = 57/86 (66.28%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            KP+ SYI LI MAI +SP +K  L+E+Y ++   +P+F+    GW+NS+RHNLSLN+CF+K   G    GKGHYW + P     FE
Sbjct:   42 KPQHSYIGLIAMAILSSPQKKMVLAEVYEWIMNEYPYFRSRGAGWRNSIRHNLSLNDCFVK--AGRAANGKGHYWAVHPACVKDFE 125

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BLAST of Forkhead F-1 vs. Ensembl Fly
Match: bin (gene:FBgn0045759 transcript:FBtr0076900)

HSP 1 Score: 137.502 bits (345), Expect = 2.410e-33
Identity = 62/96 (64.58%), Postives = 74/96 (77.08%), Query Frame = 1

Query:  928 TAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGM--GRPGKGHYWTIDPTAEFMFED 1209
            +  R+ EKP  SYI +I  AI+ SP  K TLSEIY YLQ+++ FF+GPY GWKNSVRHNLSLNECF KLPKGM  G+PGKG+YWTID  +  +FED
Sbjct:  304 SGTRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVRHNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFED 399

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BLAST of Forkhead F-1 vs. Ensembl Fly
Match: slp1 (gene:FBgn0003430 transcript:FBtr0077499)

HSP 1 Score: 113.235 bits (282), Expect = 4.259e-27
Identity = 50/92 (54.35%), Postives = 68/92 (73.91%), Query Frame = 1

Query:  928 TAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMF 1203
            TA   ++KP  SY ALI+MAIQ SP ++ TL+ IY YL   FP+F+   +GW+NS+RHNLSLN+CF K+P+    PGKG+YW +DP+AE +F
Sbjct:  113 TAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVF 204

[Close]

BLAST of Forkhead F-1 vs. Ensembl Fly
Match: fd59A (gene:FBgn0004896 transcript:FBtr0071898)

HSP 1 Score: 114.005 bits (284), Expect = 1.812e-26
Identity = 48/86 (55.81%), Postives = 65/86 (75.58%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            KP  SYIALI MAI  SP +K TLS I +++   FP+++  +  W+NS+RHNLSLN+CFIK+P+  G PGKG++WT+DP AE MF+
Sbjct:   85 KPPYSYIALITMAILQSPHKKLTLSGICDFIMSRFPYYKDKFPAWQNSIRHNLSLNDCFIKVPREPGNPGKGNFWTLDPLAEDMFD 170

[Close]

BLAST of Forkhead F-1 vs. Ensembl Fly
Match: croc (gene:FBgn0014143 transcript:FBtr0078395)

HSP 1 Score: 109.383 bits (272), Expect = 1.005e-24
Identity = 47/87 (54.02%), Postives = 65/87 (74.71%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            KP  SYIALI MAIQ +  +K TL+ IY Y+ + FP+++   QGW+NS+RHNLSLNECF+K+ +   +PGKG YWT+DP +  MF++
Sbjct:   70 KPPYSYIALIAMAIQNAADKKVTLNGIYQYIMERFPYYRDNKQGWQNSIRHNLSLNECFVKVARDDKKPGKGSYWTLDPDSYNMFDN 156

[Close]

BLAST of Forkhead F-1 vs. Ensembl Fly
Match: slp2 (gene:FBgn0004567 transcript:FBtr0077500)

HSP 1 Score: 108.227 bits (269), Expect = 1.486e-24
Identity = 47/90 (52.22%), Postives = 68/90 (75.56%), Query Frame = 1

Query:  934 KRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMF 1203
            K+ +EKP  SY ALI+MAI+ S  ++ TL+ IY Y+  N P+++   QGW+NS+RHNLSLN+CF+K+P+    PGKG+YW +DP+AE +F
Sbjct:  175 KKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSAEDVF 264

[Close]

BLAST of Forkhead F-1 vs. Ensembl Zebrafish
Match: foxf2a (forkhead box F2a [Source:ZFIN;Acc:ZDB-GENE-110407-5])

HSP 1 Score: 169.088 bits (427), Expect = 9.933e-46
Identity = 72/94 (76.60%), Postives = 82/94 (87.23%), Query Frame = 1

Query:  928 TAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            +  R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   51 SGMRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQARFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPGSEFMFEE 144

[Close]

BLAST of Forkhead F-1 vs. Ensembl Zebrafish
Match: foxf1 (forkhead box F1 [Source:NCBI gene;Acc:566407])

HSP 1 Score: 168.703 bits (426), Expect = 1.283e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   48 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 138

[Close]

BLAST of Forkhead F-1 vs. Ensembl Zebrafish
Match: foxf2b (forkhead box F2b [Source:ZFIN;Acc:ZDB-GENE-041001-130])

HSP 1 Score: 169.859 bits (429), Expect = 1.473e-45
Identity = 72/91 (79.12%), Postives = 82/91 (90.11%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ++P ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDPT+EFMFE+
Sbjct:  107 RRPEKPPYSYIALIVMAIQSAPTKRLTLSEIYQFLQTRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPTSEFMFEE 197

[Close]

BLAST of Forkhead F-1 vs. Ensembl Zebrafish
Match: foxe3 (forkhead box E3 [Source:ZFIN;Acc:ZDB-GENE-061214-6])

HSP 1 Score: 120.553 bits (301), Expect = 1.064e-28
Identity = 52/100 (52.00%), Postives = 72/100 (72.00%), Query Frame = 1

Query:  928 TAKRKSEKPEQ------SYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            T  R+ ++P Q      SYIALI MAI  SP RK TL  IY ++ + FPF++   + W+NS+RHNL+LN+CF+K+P+  GRPGKG+YWT+DP AE MF++
Sbjct:   90 TGSRRRKRPVQRGKPPYSYIALIAMAIANSPERKLTLGGIYKFIMERFPFYRENSKKWQNSIRHNLTLNDCFVKIPREPGRPGKGNYWTLDPAAEDMFDN 189

[Close]

BLAST of Forkhead F-1 vs. Ensembl Zebrafish
Match: foxe1 (forkhead box E1 [Source:ZFIN;Acc:ZDB-GENE-061116-1])

HSP 1 Score: 117.857 bits (294), Expect = 2.719e-28
Identity = 51/86 (59.30%), Postives = 65/86 (75.58%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            KP  SYIALI MAI  SP RK TL  IY ++ + FPF++   + W+NS+RHNL+LN+CFIK+P+  GRPGKG+YW +DP AE MFE
Sbjct:   40 KPPYSYIALISMAIANSPDRKLTLGGIYKFITERFPFYRDNSKKWQNSIRHNLTLNDCFIKIPREPGRPGKGNYWALDPNAEDMFE 125

[Close]

BLAST of Forkhead F-1 vs. Ensembl Xenopus
Match: ptgs1 (prostaglandin-endoperoxide synthase 1 [Source:Xenbase;Acc:XB-GENE-995315])

HSP 1 Score: 168.703 bits (426), Expect = 1.491e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   58 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQARFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 148

[Close]

BLAST of Forkhead F-1 vs. Ensembl Xenopus
Match: foxf1 (forkhead box F1 [Source:NCBI gene;Acc:734087])

HSP 1 Score: 168.318 bits (425), Expect = 1.891e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   50 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 140

[Close]

BLAST of Forkhead F-1 vs. Ensembl Xenopus
Match: FOXL1 (forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817])

HSP 1 Score: 118.242 bits (295), Expect = 5.229e-28
Identity = 51/87 (58.62%), Postives = 64/87 (73.56%), Query Frame = 1

Query:  946 EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            +KP  SYIALI MAI+ SP  + TL+ IY ++   FPF+    QGW+NS+RHNLSLN+CFIK+P+  GRPGKG YWT+DP    MFE
Sbjct:   50 QKPPYSYIALIAMAIKDSPDHRVTLNGIYQFIMDRFPFYHDNKQGWQNSIRHNLSLNDCFIKVPREKGRPGKGSYWTLDPKCLDMFE 136

[Close]

BLAST of Forkhead F-1 vs. Ensembl Xenopus
Match: ankra2 (ankyrin repeat family A member 2 [Source:Xenbase;Acc:XB-GENE-1002386])

HSP 1 Score: 116.701 bits (291), Expect = 1.150e-27
Identity = 51/92 (55.43%), Postives = 68/92 (73.91%), Query Frame = 1

Query:  931 AKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            AKR   KP  SYIALI MAI  SP +K TLS I +++   FP+++  +  W+NS+RHNLSLN+CFIK+P+  G PGKG+YWT+DP +E MF+
Sbjct:   91 AKRALVKPPYSYIALITMAILQSPHKKLTLSGICDFISSKFPYYKDKFPAWQNSIRHNLSLNDCFIKIPREPGNPGKGNYWTLDPASEDMFD 182

[Close]

BLAST of Forkhead F-1 vs. Ensembl Xenopus
Match: slc25a42 (solute carrier family 25 member 42 [Source:Xenbase;Acc:XB-GENE-5933592])

HSP 1 Score: 116.701 bits (291), Expect = 1.980e-27
Identity = 49/87 (56.32%), Postives = 66/87 (75.86%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            KP  SYIALI MAI  SP RK TL  IY ++ + FPF++   + W+NS+RHNL+LN+CF+K+P+  G PGKG+YWT+DP AE MF++
Sbjct:   82 KPPYSYIALIAMAIANSPERKLTLGGIYKFIMERFPFYRENSKKWQNSIRHNLTLNDCFVKIPREPGHPGKGNYWTLDPAAEDMFDN 168

[Close]

BLAST of Forkhead F-1 vs. Ensembl Mouse
Match: Foxf1 (forkhead box F1 [Source:MGI Symbol;Acc:MGI:1347470])

HSP 1 Score: 168.318 bits (425), Expect = 1.884e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   44 RRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 134

[Close]

BLAST of Forkhead F-1 vs. Ensembl Mouse
Match: Foxf2 (forkhead box F2 [Source:MGI Symbol;Acc:MGI:1347479])

HSP 1 Score: 167.933 bits (424), Expect = 9.385e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   96 RRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 186

[Close]

BLAST of Forkhead F-1 vs. Ensembl Mouse
Match: Foxl1 (forkhead box L1 [Source:MGI Symbol;Acc:MGI:1347469])

HSP 1 Score: 118.627 bits (296), Expect = 1.321e-28
Identity = 51/87 (58.62%), Postives = 65/87 (74.71%), Query Frame = 1

Query:  946 EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            +KP  SYIALI MAIQ +P ++ TL+ IY ++   FPF+    QGW+NS+RHNLSLNECF+K+P+  GRPGKG YWT+DP    MFE
Sbjct:   48 QKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNECFVKVPREKGRPGKGSYWTLDPRCLDMFE 134

[Close]

BLAST of Forkhead F-1 vs. Ensembl Mouse
Match: Foxi2 (forkhead box I2 [Source:MGI Symbol;Acc:MGI:3028075])

HSP 1 Score: 116.316 bits (290), Expect = 4.798e-28
Identity = 49/87 (56.32%), Postives = 67/87 (77.01%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            +P  SY ALI MAIQ++P+R+ TLS+IY Y+  NFPF++    GW+NS+RHNLSLN+CF K+P+    PGKG+YWT+DP  E MF++
Sbjct:   99 RPPYSYSALIAMAIQSAPLRRLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDENDPGKGNYWTLDPNCEKMFDN 185

[Close]

BLAST of Forkhead F-1 vs. Ensembl Mouse
Match: Foxi2 (forkhead box I2 [Source:MGI Symbol;Acc:MGI:3028075])

HSP 1 Score: 116.316 bits (290), Expect = 6.514e-28
Identity = 49/87 (56.32%), Postives = 67/87 (77.01%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            +P  SY ALI MAIQ++P+R+ TLS+IY Y+  NFPF++    GW+NS+RHNLSLN+CF K+P+    PGKG+YWT+DP  E MF++
Sbjct:  117 RPPYSYSALIAMAIQSAPLRRLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDENDPGKGNYWTLDPNCEKMFDN 203

[Close]

BLAST of Forkhead F-1 vs. UniProt/SwissProt
Match: sp|Q9W707|FXF1B_XENLA (Forkhead box protein F1-B OS=Xenopus laevis OX=8355 GN=foxf1-b PE=2 SV=1)

HSP 1 Score: 169.088 bits (427), Expect = 6.280e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   50 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 140

[Close]

BLAST of Forkhead F-1 vs. UniProt/SwissProt
Match: sp|Q9W706|FXF1A_XENLA (Forkhead box protein F1-A OS=Xenopus laevis OX=8355 GN=foxf1-a PE=2 SV=1)

HSP 1 Score: 168.703 bits (426), Expect = 8.227e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   50 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 140

[Close]

BLAST of Forkhead F-1 vs. UniProt/SwissProt
Match: sp|Q12946|FOXF1_HUMAN (Forkhead box protein F1 OS=Homo sapiens OX=9606 GN=FOXF1 PE=1 SV=2)

HSP 1 Score: 168.703 bits (426), Expect = 9.187e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   44 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 134

[Close]

BLAST of Forkhead F-1 vs. UniProt/SwissProt
Match: sp|A1L1S5|FOXF1_DANRE (Forkhead box protein F1 OS=Danio rerio OX=7955 GN=foxf1 PE=2 SV=1)

HSP 1 Score: 168.703 bits (426), Expect = 9.684e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   48 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 138

[Close]

BLAST of Forkhead F-1 vs. UniProt/SwissProt
Match: sp|Q28BS5|FOXF1_XENTR (Forkhead box protein F1 OS=Xenopus tropicalis OX=8364 GN=foxf1 PE=2 SV=1)

HSP 1 Score: 168.318 bits (425), Expect = 1.106e-44
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   50 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 140

[Close]

BLAST of Forkhead F-1 vs. TrEMBL
Match: A0A3G8G7N9 (Forkhead F-1 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=foxF-1 PE=2 SV=1)

HSP 1 Score: 493.812 bits (1270), Expect = 6.121e-168
Identity = 275/276 (99.64%), Postives = 275/276 (99.64%), Query Frame = 1

Query:  259 MPINSELYQSSFLNNSYDHQQFVNSSSLNYFNSNKKLCGFLSSTMNNFTDLDRIDYNRINDINFEQCYQPFQNSKNEHHREGNALNHFNSLSRQIELVNGDSNSLSQYIHLTQPFNNQLTNNTDPQSSPNYESNEIKPNELPVINSSIVTKDCEINNTSCLKKCEENDFVSNDSNSPTKLNEENTTDIENCSNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWK 1086
            MPINSELYQSSFLNNSYDHQQFVNSSSLNYFNSNKKLCGFLSSTMNNFTDLDRIDYNRINDINFEQCYQPFQNSKNEHHREGNALNHFNSLSRQIELVNGDSNSLSQYIHLTQPFNNQLTNNTDPQSSPNYESNEIKPNEL VINSSIVTKDCEINNTSCLKKCEENDFVSNDSNSPTKLNEENTTDIENCSNKEDDIKKEKSIEKETDTIEKMKSEKSLKSSTAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWK
Sbjct:    1 MPINSELYQSSFLNNSYDHQQFVNSSSLNYFNSNKKLCGFLSSTMNNFTDLDRIDYNRINDINFEQCYQPFQNSKNEHHREGNALNHFNSLSRQIELVNGDSNSLSQYIHLTQPFNNQLTNNTDPQSSPNYESNEIKPNELSVINSSIVTKDCEINNTSCLKKCEENDFVSNDSNSPTKLNEENTTDIENCSNKEDDIKKEKSIEKETDTIEKMKSEKSLKSSTAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWK 276

[Close]

BLAST of Forkhead F-1 vs. TrEMBL
Match: V3ZU81 (Fork-head domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_117350 PE=4 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 1.204e-48
Identity = 78/91 (85.71%), Postives = 84/91 (92.31%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+SEKP  SYIALIVMAIQA+P R+CTLSEIY YLQQ FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP AEFMFE+
Sbjct:   47 RRSEKPPYSYIALIVMAIQANPTRRCTLSEIYQYLQQKFPFFRGTYQGWKNSVRHNLSLNECFIKLPKGIGRPGKGHYWTIDPAAEFMFEE 137

[Close]

BLAST of Forkhead F-1 vs. TrEMBL
Match: D2EDJ1 (Forkhead box F protein (Fragment) OS=Patella vulgata OX=6465 GN=foxF PE=4 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 3.878e-48
Identity = 100/155 (64.52%), Postives = 111/155 (71.61%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFEDXXXXXXXXXXXXKVSTRSNSGSAFSKSPYTVTSVSYNNSSPMMFS------------PTNVRCN 1365
            R+SEKP  SYIALIVMAIQA+P R+CTLSEIY YLQQ FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP AEFMFE+G  RRRPRGFRRK       G         +  +S N++ PMM S            P N+ CN
Sbjct:    4 RRSEKPPYSYIALIVMAIQANPTRRCTLSEIYQYLQQKFPFFRGTYQGWKNSVRHNLSLNECFIKLPKGIGRPGKGHYWTIDPAAEFMFEEGSFRRRPRGFRRKCQAMKPFG--------MLNGMSMNSTPPMMGSHYDFYSQNSGMPPMNMSCN 150

[Close]

BLAST of Forkhead F-1 vs. TrEMBL
Match: A0A0B6VLL5 (Forkhead box F protein (Fragment) OS=Lottia gigantea OX=225164 GN=LgiFoxF PE=4 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 5.756e-47
Identity = 78/91 (85.71%), Postives = 84/91 (92.31%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+SEKP  SYIALIVMAIQA+P R+CTLSEIY YLQQ FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP AEFMFE+
Sbjct:   73 RRSEKPPYSYIALIVMAIQANPTRRCTLSEIYQYLQQKFPFFRGTYQGWKNSVRHNLSLNECFIKLPKGIGRPGKGHYWTIDPAAEFMFEE 163

[Close]

BLAST of Forkhead F-1 vs. TrEMBL
Match: A0A1S3HCJ4 (forkhead box protein F1-B OS=Lingula unguis OX=7574 GN=LOC106154049 PE=4 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 4.515e-46
Identity = 76/91 (83.52%), Postives = 84/91 (92.31%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+SEKP  SYIALIVMAIQA+P ++CTLSEIY +LQQ FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP AEFMFE+
Sbjct:   64 RRSEKPPYSYIALIVMAIQAAPTKRCTLSEIYQFLQQRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPAAEFMFEE 154

[Close]

BLAST of Forkhead F-1 vs. Ensembl Cavefish
Match: foxf2b (forkhead box protein F2 [Source:NCBI gene;Acc:103033774])

HSP 1 Score: 168.703 bits (426), Expect = 6.418e-46
Identity = 71/91 (78.02%), Postives = 82/91 (90.11%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ++P ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP++EFMFE+
Sbjct:   44 RRPEKPPYSYIALIVMAIQSAPAKRLTLSEIYQFLQARFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPSSEFMFEE 134

[Close]

BLAST of Forkhead F-1 vs. Ensembl Cavefish
Match: foxf1 (forkhead box F1 [Source:NCBI gene;Acc:103037372])

HSP 1 Score: 169.088 bits (427), Expect = 6.727e-46
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   45 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 135

[Close]

BLAST of Forkhead F-1 vs. Ensembl Cavefish
Match: foxf2a (forkhead box protein F2-like [Source:NCBI gene;Acc:103045769])

HSP 1 Score: 167.548 bits (423), Expect = 2.478e-45
Identity = 72/94 (76.60%), Postives = 82/94 (87.23%), Query Frame = 1

Query:  928 TAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            +  R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   51 SGMRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQARFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPGSEFMFEE 144

[Close]

BLAST of Forkhead F-1 vs. Ensembl Cavefish
Match: foxl1 (forkhead box L1 [Source:ZFIN;Acc:ZDB-GENE-040426-1181])

HSP 1 Score: 120.168 bits (300), Expect = 1.455e-30
Identity = 53/95 (55.79%), Postives = 72/95 (75.79%), Query Frame = 1

Query:  928 TAKRKS-EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            +A+R+  +KP  SYIALI MAI+++P  + TLS IY ++  NFPF+    QGW+NS+RHNLSLN+CF+K+P+  GRPGKG YWT+DP    MFE+
Sbjct:   61 SARREPPQKPPYSYIALIAMAIKSAPEERATLSGIYQFIMDNFPFYHDNKQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPKCLDMFEN 155

[Close]

BLAST of Forkhead F-1 vs. Ensembl Cavefish
Match: foxc1b (forkhead box C1b [Source:NCBI gene;Acc:79375])

HSP 1 Score: 112.849 bits (281), Expect = 6.038e-28
Identity = 49/86 (56.98%), Postives = 66/86 (76.74%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            KP  SYIALI MAIQ+S  ++ TL+ IY ++ + FPF++   QGW+NS+RHNLSLNECF+K+P+   +PGKG YWT+DP +  MFE
Sbjct:   72 KPPYSYIALITMAIQSSAEKRVTLNGIYQFIMERFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFE 157

[Close]

BLAST of Forkhead F-1 vs. Ensembl Sea Lamprey
Match: foxf2a (forkhead box F2a [Source:ZFIN;Acc:ZDB-GENE-110407-5])

HSP 1 Score: 167.548 bits (423), Expect = 6.651e-49
Identity = 71/92 (77.17%), Postives = 82/92 (89.13%), Query Frame = 1

Query:  934 KRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            +R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECF+KLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:    1 QRRPEKPPFSYIALIVMAIQSSPAKRVTLSEIYQFLQGRFPFFRGAYQGWKNSVRHNLSLNECFVKLPKGLGRPGKGHYWTIDPASEFMFEE 92

[Close]

BLAST of Forkhead F-1 vs. Ensembl Sea Lamprey
Match: foxf2a (forkhead box F2a [Source:ZFIN;Acc:ZDB-GENE-110407-5])

HSP 1 Score: 161.384 bits (407), Expect = 4.853e-47
Identity = 71/91 (78.02%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECF+KLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:    1 RRPEKPPFSYIALIVMAIQSSPAKRVTLSEIYQFLQGRFPFFRGAYQGWKNSVRHNLSLNECFVKLPKGLGRPGKGHYWTIDPASEFMFEE 91

[Close]

BLAST of Forkhead F-1 vs. Ensembl Sea Lamprey
Match: FOXC2 (forkhead box C2 [Source:HGNC Symbol;Acc:HGNC:3801])

HSP 1 Score: 114.005 bits (284), Expect = 1.293e-29
Identity = 50/93 (53.76%), Postives = 69/93 (74.19%), Query Frame = 1

Query:  931 AKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            A +   KP  SYIALI MAIQ++P +K TL+ IY ++   FPF++   QGW+NS+RHNLSLNECF+K+P+   +PGKG YW++DP +  MFE+
Sbjct:   71 APKDLVKPPYSYIALITMAIQSAPDKKVTLNGIYQFIMDKFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWSLDPDSYNMFEN 163

[Close]

BLAST of Forkhead F-1 vs. Ensembl Sea Lamprey
Match: foxl2b (forkhead box L2b [Source:ZFIN;Acc:ZDB-GENE-170803-1])

HSP 1 Score: 110.153 bits (274), Expect = 8.858e-29
Identity = 49/88 (55.68%), Postives = 65/88 (73.86%), Query Frame = 1

Query:  943 SEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            S+KP  SY+ALI MAI+ S  ++ TLS IY Y+   FPF++   +GW+NS+RHNLSLNECF+K+P+  G   KG+YWT+DP  E MFE
Sbjct:   20 SQKPPYSYVALIAMAIRESSDKRLTLSGIYQYIISKFPFYEKNKKGWQNSIRHNLSLNECFVKVPREGGGERKGNYWTLDPACEDMFE 107

[Close]

BLAST of Forkhead F-1 vs. Ensembl Sea Lamprey
Match: foxg1a (forkhead box G1a [Source:ZFIN;Acc:ZDB-GENE-990415-267])

HSP 1 Score: 109.383 bits (272), Expect = 9.370e-28
Identity = 46/91 (50.55%), Postives = 68/91 (74.73%), Query Frame = 1

Query:  931 AKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMF 1203
              +  +KP  SY ALI+MAI+ SP ++ TLS IY Y+  NFP+++   QGW+NS+RHNLSLN+CF+K+P+    PGKG+YW +DP+++ +F
Sbjct:   26 GAKGGDKPPFSYNALIMMAIRQSPEKRLTLSGIYEYIMHNFPYYRQNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVF 116

[Close]

BLAST of Forkhead F-1 vs. Ensembl Yeast
Match: HCM1 (Forkhead transcription factor; drives S-phase activation of genes involved in chromosome segregation, spindle dynamics, budding; also activates genes involved in respiration, use of alternative energy sources (like proline), NAD synthesis, oxidative stress resistance; key factor in early adaptation to nutrient deficiency and diauxic shift; suppressor of calmodulin mutants with specific SPB assembly defects; ortholog of C. elegans lifespan regulator PHA-4 [Source:SGD;Acc:S000000661])

HSP 1 Score: 85.8853 bits (211), Expect = 7.184e-18
Identity = 40/87 (45.98%), Postives = 56/87 (64.37%), Query Frame = 1

Query:  943 SEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMF 1203
            ++KP  SY  LI +AI  S   K TLS+IY+++  +FP+++     W+NS+RHNLSLN+ FIK  K     GKGH+W + P AE  F
Sbjct:  107 AKKPPYSYATLICLAILQSQEGKLTLSQIYHWIHVHFPYYKQKDASWQNSIRHNLSLNDAFIKTEKSCD--GKGHFWEVRPGAETKF 191

[Close]

BLAST of Forkhead F-1 vs. Ensembl Yeast
Match: FKH1 (Forkhead family transcription factor; rate-limiting replication origin activator; evolutionarily conserved lifespan regulator; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; regulates transcription elongation, chromatin silencing at mating loci, expression of G2/M phase genes; facilitates clustering, activation of early-firing replication origins; binds HML recombination enhancer, regulates donor preference during mating-type switching [Source:SGD;Acc:S000001393])

HSP 1 Score: 80.4925 bits (197), Expect = 2.394e-16
Identity = 35/77 (45.45%), Postives = 51/77 (66.23%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTI 1179
            KP QSY ++I  AI ++P    +L++IY ++  N+ F++     W+NSVRHNLSLN+ F K+PK  G+ GKG  W I
Sbjct:  303 KPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKI 379

[Close]

BLAST of Forkhead F-1 vs. Ensembl Yeast
Match: FKH2 (Forkhead family transcription factor; rate-limiting activator of replication origins; evolutionarily conserved regulator of lifespan; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; positively regulates transcriptional elongation; facilitates clustering, activation of early-firing replication origins; negative role in chromatin silencing at HML and HMR; major role in expression of G2/M phase genes; relocalizes to cytosol under hypoxia [Source:SGD;Acc:S000005012])

HSP 1 Score: 81.2629 bits (199), Expect = 3.145e-16
Identity = 34/77 (44.16%), Postives = 49/77 (63.64%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTI 1179
            KP  SY  +I  AI +SP    +L++IY Y+  N+ +++    GW+NS+RHNLSLN+ F K+P+    PGKG  W I
Sbjct:  340 KPPHSYATMITQAILSSPEGVISLADIYKYISSNYAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRI 416

[Close]

BLAST of Forkhead F-1 vs. Ensembl Yeast
Match: FHL1 (Regulator of ribosomal protein (RP) transcription; has forkhead associated domain that binds phosphorylated proteins; recruits coactivator Ifh1p or corepressor Crf1p to RP gene promoters; also has forkhead DNA-binding domain though in vitro DNA binding assays give inconsistent results; computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p motifs at others; suppresses RNA pol III and splicing factor prp4 mutants [Source:SGD;Acc:S000006308])

HSP 1 Score: 64.3142 bits (155), Expect = 4.668e-11
Identity = 35/87 (40.23%), Postives = 53/87 (60.92%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQA-SPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            KP  SY A++   I+  S  +  +LSEIY  +++ FP+++    GW++SVRHNLSLN+ F K+ K     GKG  W +D   E++ E
Sbjct:  461 KPTVSYSAMLTTCIRKYSTAKGMSLSEIYAGIRELFPYYKYCPDGWQSSVRHNLSLNKSFRKVSK----EGKGWLWGLD--EEYIAE 541

[Close]

BLAST of Forkhead F-1 vs. Ensembl Nematostella
Match: EDO45105 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTX1])

HSP 1 Score: 112.849 bits (281), Expect = 9.064e-30
Identity = 48/87 (55.17%), Postives = 68/87 (78.16%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            KP  SYIALI MAI  SP RK TLS+I  ++++ FP+++  +  W+NS+RHNLSLN+CF+K+P+  G PGKG+YWT+DP +E MF++
Sbjct:    3 KPPYSYIALITMAILQSPQRKLTLSDICEFIKRRFPYYREKFPSWQNSIRHNLSLNDCFVKMPREPGNPGKGNYWTLDPASEGMFDN 89

[Close]

BLAST of Forkhead F-1 vs. Ensembl Nematostella
Match: EDO45102 (Forkhead domain protein E; Predicted protein [Source:UniProtKB/TrEMBL;Acc:Q3LUS8])

HSP 1 Score: 120.939 bits (302), Expect = 1.786e-29
Identity = 55/87 (63.22%), Postives = 69/87 (79.31%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            KP  SYIALI MAI +SP R+ TLSEIY+++ Q FPF+Q     WKNS+RHNL+LN+CFIKLP+   RPGKG+YWTIDPT+  MF++
Sbjct:   43 KPPYSYIALICMAITSSPQRQLTLSEIYDFISQRFPFYQTCSIKWKNSIRHNLTLNDCFIKLPREPNRPGKGNYWTIDPTSVDMFDN 129

[Close]

BLAST of Forkhead F-1 vs. Ensembl Nematostella
Match: EDO46828 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP00])

HSP 1 Score: 108.612 bits (270), Expect = 3.213e-28
Identity = 46/83 (55.42%), Postives = 65/83 (78.31%), Query Frame = 1

Query:  946 EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAE 1194
            EKP  SY ALI+MAI+ S  ++ TLS IY Y+ +NFP+++   QGW+NS+RHNLSLN+CF+K+P+    PGKG+YW +DP+A+
Sbjct:    1 EKPAFSYNALIMMAIRGSEEKRLTLSGIYEYIMKNFPYYRNNKQGWQNSIRHNLSLNKCFVKVPRNYDDPGKGNYWMLDPSAD 83

[Close]

BLAST of Forkhead F-1 vs. Ensembl Nematostella
Match: EDO47812 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL76])

HSP 1 Score: 108.227 bits (269), Expect = 3.832e-28
Identity = 48/86 (55.81%), Postives = 64/86 (74.42%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            KP  SY+ALI MAI+ SP ++ TL+ IY Y+   FP+++   +GW+NS+RHNLSLNECFIK+P+  G   KG+YWT+DP  E MFE
Sbjct:    1 KPPYSYVALIAMAIRESPEKRLTLNGIYQYIISKFPYYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFE 86

[Close]

BLAST of Forkhead F-1 vs. Ensembl Nematostella
Match: EDO42654 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0W7])

HSP 1 Score: 107.457 bits (267), Expect = 5.807e-28
Identity = 48/87 (55.17%), Postives = 65/87 (74.71%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            KP  SY+ALI MAI+ S  +K TLS IY ++ +NFP+++   +GW+NS+RHNLSLN+CF+K+P+    PGKG YW +DP  E MFED
Sbjct:    3 KPPYSYVALISMAIKQSKGQKITLSGIYQFIIENFPYYRLNKRGWQNSIRHNLSLNKCFVKIPRERSDPGKGCYWALDPAYEEMFED 89

[Close]

BLAST of Forkhead F-1 vs. Ensembl Medaka
Match: foxf2a (forkhead box protein F2 [Source:NCBI gene;Acc:101168243])

HSP 1 Score: 170.629 bits (431), Expect = 1.840e-46
Identity = 73/94 (77.66%), Postives = 82/94 (87.23%), Query Frame = 1

Query:  928 TAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            +  R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY YLQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   47 SGMRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQYLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPGSEFMFEE 140

[Close]

BLAST of Forkhead F-1 vs. Ensembl Medaka
Match: foxf2 (forkhead box F2 [Source:NCBI gene;Acc:100301612])

HSP 1 Score: 168.703 bits (426), Expect = 9.232e-46
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   53 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQARFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPGSEFMFEE 143

[Close]

BLAST of Forkhead F-1 vs. Ensembl Medaka
Match: foxf1 (forkhead box F1 [Source:NCBI gene;Acc:101171563])

HSP 1 Score: 168.703 bits (426), Expect = 1.029e-45
Identity = 72/91 (79.12%), Postives = 81/91 (89.01%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R+ EKP  SYIALIVMAIQ+SP ++ TLSEIY +LQ  FPFF+G YQGWKNSVRHNLSLNECFIKLPKG+GRPGKGHYWTIDP +EFMFE+
Sbjct:   49 RRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEE 139

[Close]

BLAST of Forkhead F-1 vs. Ensembl Medaka
Match: foxe3 (forkhead box E3 [Source:NCBI gene;Acc:100301611])

HSP 1 Score: 119.398 bits (298), Expect = 1.844e-28
Identity = 50/87 (57.47%), Postives = 67/87 (77.01%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            KP  SYIALI MAI  SP RK TL  IY ++ + FPF++   + W+NS+RHNL+LN+CF+K+P+  GRPGKG+YWT+DP AE MF++
Sbjct:   80 KPPYSYIALIAMAIANSPERKLTLGGIYKFIMERFPFYRENSKKWQNSIRHNLTLNDCFVKIPREPGRPGKGNYWTLDPAAEDMFDN 166

[Close]

BLAST of Forkhead F-1 vs. Ensembl Medaka
Match: foxl1 (forkhead box L1 [Source:NCBI gene;Acc:100144369])

HSP 1 Score: 117.087 bits (292), Expect = 2.881e-28
Identity = 50/87 (57.47%), Postives = 65/87 (74.71%), Query Frame = 1

Query:  946 EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            +KP  SYIALI MAI+++P ++ TLS IY ++   FPF+    QGW+NS+RHNLSLN+CFIK+P+  GRPGKG YWT+D     MFE
Sbjct:   49 QKPPYSYIALIAMAIKSAPGQRATLSGIYQFIMDRFPFYHDNKQGWQNSIRHNLSLNDCFIKVPRERGRPGKGSYWTLDTKCLDMFE 135

[Close]

BLAST of Forkhead F-1 vs. Planmine SMEST
Match: SMESG000066497.1 (SMESG000066497.1)

HSP 1 Score: 1204.12 bits (3114), Expect = 0.000e+0
Identity = 693/695 (99.71%), Postives = 694/695 (99.86%), Query Frame = 1

Query:   82 MNNADSNRSGVYLQSQFSHQLLGSFESPISSTQLKETAAVNSQEIKSEIHYSPEFSTDYMPINSELYQSSFLNNSYDHQQFVNSSSLNYFNSNKKLCGFLSSTMNNFTDLDRIDYNRINDINFEQCYQPFQNSKNEHHREGNALNHFNSLSRQIELVNGDSNSLSQYIHLTQPFNNQLTNNTDPQSSPNYESNEIKPNELPVINSSIVTKDCEINNTSCLKKCEENDFVSNDSNSPTKLNEENTTDIENCSNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFEDXXXXXXXXXXXXKVSTRSNSGSAFSKSPYTVTSVSYNNSSPMMFSPTNVRCNQLGNSASSCNSMNNLNGPVTDNMPPLFDMYHQSFGLFTQQETNDPMKTVMPNYPQHDSGFFTXXXXXXXXXXXXXXKQEIPTASSLFHPNFXXXXXXXXXXXXXXXXXXXXXYVSGNSRNSPLFTSLSSTLQAQNISELKISDQSSFHSPQXXXXXXXXXXXXXXLYSNWFPNGPVEAAKYFIDHSSESERIENLYASSALPRLSNIHSENDEILERNSMYQPYMTDCLLPYLPSSQMFNIANMTDVRSSNINIDNADRSIWVHNKF 2166
            MNNADSNRSGVYLQSQFSHQLLGSFESPISSTQLKETAAVN QEIKSEIHYSPEFSTDYMPINSELYQSSFLNNSYDHQQFVNSSSLNYFNSNKKLCGFLSSTMNNFTDLDRIDYNRINDINFEQCYQPFQNSKNEHHREGNALNHFNSLSRQIELVNGDSNSLSQYIHLTQPFNNQLTNNTDPQSSPNYESNEIKPNELPVINSSIVTKDCEINNTSCLKKCE+NDFVSNDSNSPTKLNEENTTDIENCSNKEDDIKKEKSIEKETDTIEKMKSEKSLKSSTAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFEDGGNRRRPRGFRRKVSTRSNSGSAFSKSPYTVTSVSYNNSSPMMFSPTNVRCNQLGNSASSCNSMNNLNGPVTDNMPPLFDMYHQSFGLFTQQETNDPMKTVMPNYPQHDSGFFTDSFYPNSSSDSSFNKQEIPTASSLFHPNFMSNTISQTSNSSSMSHPSISPYVSGNSRNSPLFTSLSSTLQAQNISELKISDQSSFHSPQSSTSSTVAAVAAASLYSNWFPNGPVEAAKYFIDHSSESERIENLYASSALPRLSNIHSENDEILERNSMYQPYMTDCLLPYLPSSQMFNIANMTDVRSSNINIDNADRSIWVHNKF
Sbjct:    1 MNNADSNRSGVYLQSQFSHQLLGSFESPISSTQLKETAAVNCQEIKSEIHYSPEFSTDYMPINSELYQSSFLNNSYDHQQFVNSSSLNYFNSNKKLCGFLSSTMNNFTDLDRIDYNRINDINFEQCYQPFQNSKNEHHREGNALNHFNSLSRQIELVNGDSNSLSQYIHLTQPFNNQLTNNTDPQSSPNYESNEIKPNELPVINSSIVTKDCEINNTSCLKKCEDNDFVSNDSNSPTKLNEENTTDIENCSNKEDDIKKEKSIEKETDTIEKMKSEKSLKSSTAKRKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFEDGGNRRRPRGFRRKVSTRSNSGSAFSKSPYTVTSVSYNNSSPMMFSPTNVRCNQLGNSASSCNSMNNLNGPVTDNMPPLFDMYHQSFGLFTQQETNDPMKTVMPNYPQHDSGFFTDSFYPNSSSDSSFNKQEIPTASSLFHPNFMSNTISQTSNSSSMSHPSISPYVSGNSRNSPLFTSLSSTLQAQNISELKISDQSSFHSPQSSTSSTVAAVAAASLYSNWFPNGPVEAAKYFIDHSSESERIENLYASSALPRLSNIHSENDEILERNSMYQPYMTDCLLPYLPSSQMFNIANMTDVRSSNINIDNADRSIWVHNKF 695

[Close]

BLAST of Forkhead F-1 vs. Planmine SMEST
Match: SMESG000075929.1 (SMESG000075929.1)

HSP 1 Score: 139.428 bits (350), Expect = 1.628e-37
Identity = 59/87 (67.82%), Postives = 73/87 (83.91%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            KP  SYI+LI MAIQASP ++CTL+EIY YL ++F FF+G YQGWKNS+RHNLSLN+CFIK+PKG GR GKGHYWT++  A F+F +
Sbjct:   34 KPPFSYISLIAMAIQASPYQQCTLNEIYEYLSEHFKFFRGEYQGWKNSIRHNLSLNDCFIKIPKGFGRIGKGHYWTMNENASFLFNE 120

[Close]

BLAST of Forkhead F-1 vs. Planmine SMEST
Match: SMESG000075929.1 (SMESG000075929.1)

HSP 1 Score: 139.428 bits (350), Expect = 1.883e-37
Identity = 59/87 (67.82%), Postives = 73/87 (83.91%), Query Frame = 1

Query:  949 KPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            KP  SYI+LI MAIQASP ++CTL+EIY YL ++F FF+G YQGWKNS+RHNLSLN+CFIK+PKG GR GKGHYWT++  A F+F +
Sbjct:   36 KPPFSYISLIAMAIQASPYQQCTLNEIYEYLSEHFKFFRGEYQGWKNSIRHNLSLNDCFIKIPKGFGRIGKGHYWTMNENASFLFNE 122

[Close]

BLAST of Forkhead F-1 vs. Planmine SMEST
Match: SMESG000015673.1 (SMESG000015673.1)

HSP 1 Score: 117.857 bits (294), Expect = 6.904e-28
Identity = 50/91 (54.95%), Postives = 65/91 (71.43%), Query Frame = 1

Query:  937 RKSEKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFED 1209
            R   KP  SYIALI MA+ A P +K TLS IY ++ + FP+++   QGW+NS+RHNLSLNECFIK+P+   +PGKG YW + P A  MFE+
Sbjct:   69 RDLVKPPYSYIALITMAVHAHPEKKVTLSGIYQFIMEKFPYYRENKQGWQNSIRHNLSLNECFIKIPRDDKKPGKGSYWALHPQAYNMFEN 159

[Close]

BLAST of Forkhead F-1 vs. Planmine SMEST
Match: SMESG000021434.1 (SMESG000021434.1)

HSP 1 Score: 112.079 bits (279), Expect = 3.752e-27
Identity = 49/87 (56.32%), Postives = 64/87 (73.56%), Query Frame = 1

Query:  946 EKPEQSYIALIVMAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIKLPKGMGRPGKGHYWTIDPTAEFMFE 1206
            EKP  SYIALI MAI+ +P +K TLS IY ++  NFPF+    QGW+NS+RHNLSLN+CFIK+ +    PGKG+YWT++   E MF+
Sbjct:   63 EKPPYSYIALIAMAIRNTPDKKITLSGIYKFITDNFPFYHRNKQGWQNSIRHNLSLNDCFIKIARDKNNPGKGNYWTLNENFEEMFD 149

The following BLAST results are available for this feature:

BLAST of Forkhead F-1 vs. Ensembl Human
BLAST of Forkhead F-1 vs. Ensembl Celegans
BLAST of Forkhead F-1 vs. Ensembl Fly
BLAST of Forkhead F-1 vs. Ensembl Zebrafish
BLAST of Forkhead F-1 vs. Ensembl Xenopus
BLAST of Forkhead F-1 vs. Ensembl Mouse
BLAST of Forkhead F-1 vs. UniProt/SwissProt
BLAST of Forkhead F-1 vs. TrEMBL
BLAST of Forkhead F-1 vs. Ensembl Cavefish
BLAST of Forkhead F-1 vs. Ensembl Sea Lamprey
BLAST of Forkhead F-1 vs. Ensembl Yeast
BLAST of Forkhead F-1 vs. Ensembl Nematostella
BLAST of Forkhead F-1 vs. Ensembl Medaka
BLAST of Forkhead F-1 vs. Planmine SMEST

BLAST of Forkhead F-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
FOXF1	1.913e-45	79.12	forkhead box F1 [Source:HGNC Symbol;Acc:HGNC:3809]	[more]
FOXF2	1.476e-44	79.12	forkhead box F2 [Source:HGNC Symbol;Acc:HGNC:3810]	[more]
FOXI2	6.587e-28	57.47	forkhead box I2 [Source:HGNC Symbol;Acc:HGNC:32448...	[more]
FOXL1	2.045e-27	57.47	forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817]	[more]
FOXE1	6.234e-27	55.81	forkhead box E1 [Source:HGNC Symbol;Acc:HGNC:3806]	[more]

BLAST of Forkhead F-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
let-381	1.780e-32	60.42	pep chromosome:WBcel235:I:6320289:6324018:-1 gene:...	[more]
fkh-2	7.657e-26	55.42	ForKHead transcription factor family [Source:UniP...	[more]
unc-130	1.580e-24	50.00	pep chromosome:WBcel235:II:11281986:11283953:1 gen...	[more]
lin-31	1.800e-24	52.27	pep chromosome:WBcel235:II:3982549:3986944:1 gene:...	[more]
fkh-10	3.732e-23	48.84	ForKHead transcription factor family [Source:UniP...	[more]

BLAST of Forkhead F-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
bin	2.410e-33	64.58	gene:FBgn0045759 transcript:FBtr0076900	[more]
slp1	4.259e-27	54.35	gene:FBgn0003430 transcript:FBtr0077499	[more]
fd59A	1.812e-26	55.81	gene:FBgn0004896 transcript:FBtr0071898	[more]
croc	1.005e-24	54.02	gene:FBgn0014143 transcript:FBtr0078395	[more]
slp2	1.486e-24	52.22	gene:FBgn0004567 transcript:FBtr0077500	[more]

BLAST of Forkhead F-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
foxf2a	9.933e-46	76.60	forkhead box F2a [Source:ZFIN;Acc:ZDB-GENE-110407-...	[more]
foxf1	1.283e-45	79.12	forkhead box F1 [Source:NCBI gene;Acc:566407]	[more]
foxf2b	1.473e-45	79.12	forkhead box F2b [Source:ZFIN;Acc:ZDB-GENE-041001-...	[more]
foxe3	1.064e-28	52.00	forkhead box E3 [Source:ZFIN;Acc:ZDB-GENE-061214-6...	[more]
foxe1	2.719e-28	59.30	forkhead box E1 [Source:ZFIN;Acc:ZDB-GENE-061116-1...	[more]

BLAST of Forkhead F-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ptgs1	1.491e-45	79.12	prostaglandin-endoperoxide synthase 1 [Source:Xenb...	[more]
foxf1	1.891e-45	79.12	forkhead box F1 [Source:NCBI gene;Acc:734087]	[more]
FOXL1	5.229e-28	58.62	forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817]	[more]
ankra2	1.150e-27	55.43	ankyrin repeat family A member 2 [Source:Xenbase;A...	[more]
slc25a42	1.980e-27	56.32	solute carrier family 25 member 42 [Source:Xenbase...	[more]

BLAST of Forkhead F-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Foxf1	1.884e-45	79.12	forkhead box F1 [Source:MGI Symbol;Acc:MGI:1347470...	[more]
Foxf2	9.385e-45	79.12	forkhead box F2 [Source:MGI Symbol;Acc:MGI:1347479...	[more]
Foxl1	1.321e-28	58.62	forkhead box L1 [Source:MGI Symbol;Acc:MGI:1347469...	[more]
Foxi2	4.798e-28	56.32	forkhead box I2 [Source:MGI Symbol;Acc:MGI:3028075...	[more]
Foxi2	6.514e-28	56.32	forkhead box I2 [Source:MGI Symbol;Acc:MGI:3028075...	[more]

BLAST of Forkhead F-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9W707\|FXF1B_XENLA	6.280e-45	79.12	Forkhead box protein F1-B OS=Xenopus laevis OX=835...	[more]
sp\|Q9W706\|FXF1A_XENLA	8.227e-45	79.12	Forkhead box protein F1-A OS=Xenopus laevis OX=835...	[more]
sp\|Q12946\|FOXF1_HUMAN	9.187e-45	79.12	Forkhead box protein F1 OS=Homo sapiens OX=9606 GN...	[more]
sp\|A1L1S5\|FOXF1_DANRE	9.684e-45	79.12	Forkhead box protein F1 OS=Danio rerio OX=7955 GN=...	[more]
sp\|Q28BS5\|FOXF1_XENTR	1.106e-44	79.12	Forkhead box protein F1 OS=Xenopus tropicalis OX=8...	[more]

BLAST of Forkhead F-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A3G8G7N9	6.121e-168	99.64	Forkhead F-1 (Fragment) OS=Schmidtea mediterranea ...	[more]
V3ZU81	1.204e-48	85.71	Fork-head domain-containing protein (Fragment) OS=...	[more]
D2EDJ1	3.878e-48	64.52	Forkhead box F protein (Fragment) OS=Patella vulga...	[more]
A0A0B6VLL5	5.756e-47	85.71	Forkhead box F protein (Fragment) OS=Lottia gigant...	[more]
A0A1S3HCJ4	4.515e-46	83.52	forkhead box protein F1-B OS=Lingula unguis OX=757...	[more]

BLAST of Forkhead F-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
foxf2b	6.418e-46	78.02	forkhead box protein F2 [Source:NCBI gene;Acc:1030...	[more]
foxf1	6.727e-46	79.12	forkhead box F1 [Source:NCBI gene;Acc:103037372]	[more]
foxf2a	2.478e-45	76.60	forkhead box protein F2-like [Source:NCBI gene;Acc...	[more]
foxl1	1.455e-30	55.79	forkhead box L1 [Source:ZFIN;Acc:ZDB-GENE-040426-1...	[more]
foxc1b	6.038e-28	56.98	forkhead box C1b [Source:NCBI gene;Acc:79375]	[more]

BLAST of Forkhead F-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
foxf2a	6.651e-49	77.17	forkhead box F2a [Source:ZFIN;Acc:ZDB-GENE-110407-...	[more]
foxf2a	4.853e-47	78.02	forkhead box F2a [Source:ZFIN;Acc:ZDB-GENE-110407-...	[more]
FOXC2	1.293e-29	53.76	forkhead box C2 [Source:HGNC Symbol;Acc:HGNC:3801]	[more]
foxl2b	8.858e-29	55.68	forkhead box L2b [Source:ZFIN;Acc:ZDB-GENE-170803-...	[more]
foxg1a	9.370e-28	50.55	forkhead box G1a [Source:ZFIN;Acc:ZDB-GENE-990415-...	[more]

BLAST of Forkhead F-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4


Match Name	E-value	Identity	Description
HCM1	7.184e-18	45.98	Forkhead transcription factor; drives S-phase acti...	[more]
FKH1	2.394e-16	45.45	Forkhead family transcription factor; rate-limitin...	[more]
FKH2	3.145e-16	44.16	Forkhead family transcription factor; rate-limitin...	[more]
FHL1	4.668e-11	40.23	Regulator of ribosomal protein (RP) transcription;...	[more]

BLAST of Forkhead F-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO45105	9.064e-30	55.17	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45102	1.786e-29	63.22	Forkhead domain protein E; Predicted protein [Sou...	[more]
EDO46828	3.213e-28	55.42	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47812	3.832e-28	55.81	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42654	5.807e-28	55.17	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Forkhead F-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
foxf2a	1.840e-46	77.66	forkhead box protein F2 [Source:NCBI gene;Acc:1011...	[more]
foxf2	9.232e-46	79.12	forkhead box F2 [Source:NCBI gene;Acc:100301612]	[more]
foxf1	1.029e-45	79.12	forkhead box F1 [Source:NCBI gene;Acc:101171563]	[more]
foxe3	1.844e-28	57.47	forkhead box E3 [Source:NCBI gene;Acc:100301611]	[more]
foxl1	2.881e-28	57.47	forkhead box L1 [Source:NCBI gene;Acc:100144369]	[more]

BLAST of Forkhead F-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000066497.1	0.000e+0	99.71	SMESG000066497.1	[more]
SMESG000075929.1	1.628e-37	67.82	SMESG000075929.1	[more]
SMESG000075929.1	1.883e-37	67.82	SMESG000075929.1	[more]
SMESG000015673.1	6.904e-28	54.95	SMESG000015673.1	[more]
SMESG000021434.1	3.752e-27	56.32	SMESG000021434.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30021716 ID=SMED30021716|Name=Forkhead F-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2253bp
CAACCACAATTTAACTAAAGACGATCATTGATAGTTTAAAATTTATATTT
TAATCAATTTTACACAATACAATAACGTTCAATGAACAATGCAGATTCCA
ATCGTTCGGGAGTTTATCTTCAATCACAATTCTCTCATCAACTTCTAGGA
TCATTTGAAAGTCCTATTTCCAGCACACAGCTTAAAGAAACAGCTGCAGT
AAATAGCCAGGAAATAAAATCAGAAATTCATTATTCTCCAGAATTTTCCA
CAGATTATATGCCAATTAATTCAGAGCTTTATCAATCAAGTTTCTTGAAC
AATTCTTACGACCATCAACAATTTGTCAATTCCTCATCATTAAATTATTT
CAATTCCAATAAAAAGTTATGTGGGTTTTTATCATCAACAATGAATAACT
TTACGGATCTAGACAGAATAGATTACAATAGAATTAATGATATTAATTTT
GAACAATGCTATCAGCCTTTTCAAAACTCTAAAAATGAACACCATAGAGA
AGGAAATGCGTTAAATCATTTTAATTCATTATCTCGACAAATTGAATTAG
TGAATGGAGATTCCAATAGTCTTTCTCAATACATTCACTTAACTCAGCCT
TTCAATAATCAACTTACTAATAACACAGATCCTCAAAGCAGTCCAAATTA
TGAATCTAACGAAATTAAACCTAATGAATTACCTGTCATAAATTCATCTA
TCGTTACTAAAGATTGTGAAATTAACAATACTTCATGTTTAAAAAAATGT
GAAGAAAATGATTTTGTCAGTAATGATAGCAATTCTCCAACAAAGCTCAA
TGAAGAAAATACTACCGACATTGAAAATTGTAGTAATAAAGAAGATGATA
TTAAAAAAGAAAAATCTATTGAAAAAGAAACTGATACTATTGAAAAAATG
AAATCAGAAAAATCTTTAAAATCATCAACTGCAAAACGTAAATCCGAAAA
ACCTGAACAATCATATATTGCATTAATAGTTATGGCTATTCAAGCTTCAC
CAATAAGAAAATGTACATTAAGTGAAATATACAATTATTTGCAGCAAAAT
TTTCCCTTTTTTCAAGGTCCTTATCAAGGATGGAAAAATTCTGTTCGACA
CAATTTATCTTTAAATGAATGTTTTATCAAACTTCCCAAAGGTATGGGCA
GACCTGGTAAAGGACATTACTGGACAATCGATCCTACTGCTGAATTTATG
TTTGAAGACGGAGGAAATAGAAGAAGACCAAGAGGTTTCAGAAGAAAAGT
ATCTACACGAAGCAACTCTGGTTCCGCTTTCTCGAAGTCTCCATACACAG
TCACTTCAGTTTCATATAATAATAGCAGTCCAATGATGTTTTCACCTACT
AATGTACGATGCAATCAATTAGGAAATAGCGCATCATCTTGTAATTCCAT
GAATAATCTTAATGGACCAGTTACTGACAATATGCCACCTCTTTTCGATA
TGTATCATCAAAGCTTTGGTCTTTTTACTCAGCAGGAAACAAATGATCCA
ATGAAAACTGTAATGCCAAATTATCCTCAGCACGATTCCGGATTTTTTAC
AGATTCTTTCTATCCAAATTCATCATCAGATTCCAGTTTTAATAAACAAG
AGATTCCAACAGCTTCATCATTATTTCATCCTAATTTTATGTCTAATACA
ATTAGTCAAACGTCAAATTCTTCAAGTATGTCTCATCCTTCCATATCTCC
TTATGTCTCAGGAAATTCTAGAAATAGTCCTTTATTTACTTCGCTTTCTT
CAACTTTGCAAGCTCAGAATATATCTGAATTAAAAATTTCTGATCAGTCA
TCATTTCATTCTCCTCAATCATCAACTTCTTCCACTGTAGCAGCTGTTGC
CGCTGCTTCGCTTTATTCAAATTGGTTTCCCAATGGACCTGTTGAGGCAG
CTAAATATTTTATAGACCATTCCTCAGAGTCAGAGAGAATCGAAAATTTA
TATGCATCGAGCGCTTTACCTAGACTTTCAAACATACATTCAGAAAATGA
TGAAATTCTTGAAAGAAATTCAATGTATCAACCATACATGACAGATTGTT
TATTACCATACTTACCTTCGAGTCAAATGTTTAATATAGCAAACATGACA
GACGTACGTTCCAGTAACATAAACATTGATAATGCGGACAGATCCATCTG
GGTTCACAACAAATTTTGATTAAAATAATTTTGATTTAATTGTATATATT
CCCATAAATGTATATCATGATTGAAAAGTTATAATTCAATTGTGGCAGAC
CAC

protein sequence of SMED30021716-orf-1

>SMED30021716-orf-1 ID=SMED30021716-orf-1|Name=SMED30021716-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=696bp
MNNADSNRSGVYLQSQFSHQLLGSFESPISSTQLKETAAVNSQEIKSEIH
YSPEFSTDYMPINSELYQSSFLNNSYDHQQFVNSSSLNYFNSNKKLCGFL
SSTMNNFTDLDRIDYNRINDINFEQCYQPFQNSKNEHHREGNALNHFNSL
SRQIELVNGDSNSLSQYIHLTQPFNNQLTNNTDPQSSPNYESNEIKPNEL
PVINSSIVTKDCEINNTSCLKKCEENDFVSNDSNSPTKLNEENTTDIENC
SNKEDDIKKEKSIEKETDTIEKMKSEKSLKSSTAKRKSEKPEQSYIALIV
MAIQASPIRKCTLSEIYNYLQQNFPFFQGPYQGWKNSVRHNLSLNECFIK
LPKGMGRPGKGHYWTIDPTAEFMFEDGGNRRRPRGFRRKVSTRSNSGSAF
SKSPYTVTSVSYNNSSPMMFSPTNVRCNQLGNSASSCNSMNNLNGPVTDN
MPPLFDMYHQSFGLFTQQETNDPMKTVMPNYPQHDSGFFTDSFYPNSSSD
SSFNKQEIPTASSLFHPNFMSNTISQTSNSSSMSHPSISPYVSGNSRNSP
LFTSLSSTLQAQNISELKISDQSSFHSPQSSTSSTVAAVAAASLYSNWFP
NGPVEAAKYFIDHSSESERIENLYASSALPRLSNIHSENDEILERNSMYQ
PYMTDCLLPYLPSSQMFNIANMTDVRSSNINIDNADRSIWVHNKF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002075	pigment cell
PLANA:0003104	enteric muscle cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036388	WH-like_DNA-bd_sf
IPR036390	WH_DNA-bd_sf
IPR001766	Fork_head_dom
IPR011991	WHTH_DNA-bd_dom
IPR030456	TF_fork_head_CS_2

Vocabulary: **molecular function**
Term	Definition
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity, sequence-specific DNA binding
GO:0003677	DNA binding

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001766	Fork head domain	PRINTS	PR00053	FORKHEAD	coord: 311..328 score: 40.7 coord: 290..303 score: 65.19 coord: 334..351 score: 69.71
IPR001766	Fork head domain	SMART	SM00339	forkneu4	coord: 288..378 e-value: 5.1E-49 score: 178.9
IPR001766	Fork head domain	PFAM	PF00250	Forkhead	coord: 289..374 e-value: 2.7E-33 score: 114.1
IPR001766	Fork head domain	PROSITE	PS50039	FORK_HEAD_3	coord: 290..384 score: 33.996
IPR001766	Fork head domain	CDD	cd00059	FH	coord: 290..367 e-value: 5.48073E-40 score: 139.226
IPR036388	Winged helix-like DNA-binding domain superfamily	GENE3D	G3DSA:1.10.10.10		coord: 276..384 e-value: 2.7E-38 score: 132.1
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 268..287
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 175..198
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 233..262
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 247..262
None	No IPR available	PANTHER	PTHR46262:SF2	FORKHEAD BOX PROTEIN BINIOU	coord: 150..580
None	No IPR available	PANTHER	PTHR46262	FAMILY NOT NAMED	coord: 150..580
IPR030456	Fork head domain conserved site 2	PROSITE	PS00658	FORK_HEAD_2	coord: 334..340
IPR036390	Winged helix DNA-binding domain superfamily	SUPERFAMILY	SSF46785	"Winged helix" DNA-binding domain	coord: 289..383