Ras association domain family member 7a

Overview


Name	Ras association domain family member 7a
Smed ID	SMED30021652
Length (bp)	851

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ras association domain family member 7a (SMED30021652) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras association domain family member 7a (SMED30021652) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras association domain family member 7a (SMED30021652) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras association domain family member 7a (SMED30021652) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30021652

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30021652	SMESG000080298.1	dd_Smed_v4_3722_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30021652	SMESG000080298.1	dd_Smed_v4_3722_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30021652	SMESG000080298.1	dd_Smed_v4_3722_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30021652	SMESG000080298.1	dd_Smed_v4_3722_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Human
Match: RASSF8 (Ras association domain family member 8 [Source:HGNC Symbol;Acc:HGNC:13232])

HSP 1 Score: 67.781 bits (164), Expect = 8.446e-14
Identity = 40/85 (47.06%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P+  L K   Y SD  +Q ILRR+  S
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASD--VQLILRRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Human
Match: RASSF8 (Ras association domain family member 8 [Source:HGNC Symbol;Acc:HGNC:13232])

HSP 1 Score: 67.781 bits (164), Expect = 1.116e-13
Identity = 40/85 (47.06%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P+  L K   Y SD  +Q ILRR+  S
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASD--VQLILRRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Human
Match: RASSF8 (Ras association domain family member 8 [Source:HGNC Symbol;Acc:HGNC:13232])

HSP 1 Score: 69.3218 bits (168), Expect = 2.042e-13
Identity = 40/85 (47.06%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P+  L K   Y SD  +Q ILRR+  S
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASD--VQLILRRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Human
Match: RASSF8 (Ras association domain family member 8 [Source:HGNC Symbol;Acc:HGNC:13232])

HSP 1 Score: 68.9366 bits (167), Expect = 2.069e-13
Identity = 40/85 (47.06%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P+  L K   Y SD  +Q ILRR+  S
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASD--VQLILRRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Human
Match: RASSF8 (Ras association domain family member 8 [Source:HGNC Symbol;Acc:HGNC:13232])

HSP 1 Score: 67.781 bits (164), Expect = 2.143e-13
Identity = 40/85 (47.06%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P+  L K   Y SD  +Q ILRR+  S
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASD--VQLILRRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Celegans
Match: K05B2.2 (pep chromosome:WBcel235:X:4907290:4912323:1 gene:WBGene00019403.1 transcript:K05B2.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K05B2.2)

HSP 1 Score: 56.225 bits (134), Expect = 6.172e-9
Identity = 32/85 (37.65%), Postives = 46/85 (54.12%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSD-KNIQF-ILRRSQNSE 412
            ME+K+  +G+ R V GVT+  TC ++I  LA   S  G   +     + E  L P DRPL+ L+K+     N+ F +LR  QN E
Sbjct:    1 MELKINIDGLERSVSGVTDTTTCSQIIYALAHATSQRGRFVMVEKYRNVERRLAPTDRPLETLRKWREHAANVTFQMLRVDQNDE 85

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Fly
Match: RASSF8 (gene:FBgn0261986 transcript:FBtr0084898)

HSP 1 Score: 66.2402 bits (160), Expect = 5.829e-12
Identity = 34/82 (41.46%), Postives = 46/82 (56.10%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKN-IQFILRRSQN 406
            ME+KVW EG+ R VCGVT   TC +V+  LA      G   L     + E  L P + P+ +L K+    N +QFIL+RS+N
Sbjct:    1 MELKVWVEGIQRIVCGVTVNTTCQDVVFALAHATGKVGRFTLIERWRNNERHLAPNENPMKLLLKWGEYANDVQFILQRSEN 82

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Zebrafish
Match: rassf8a (Ras association domain family member 8a [Source:ZFIN;Acc:ZDB-GENE-091014-4])

HSP 1 Score: 71.2478 bits (173), Expect = 1.307e-13
Identity = 40/89 (44.94%), Postives = 49/89 (55.06%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRP---LDILKKYTSDKNIQFILRRSQNSENMY 421
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P   L+   +Y  D  +QFIL R+  S N Y
Sbjct:    1 MELKVWVDGVQRVVCGVTEATTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLVPHESPVASLNTWGQYAGD--VQFILHRTGPSLNEY 87

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Zebrafish
Match: rassf7b (Ras association domain family member 7b [Source:ZFIN;Acc:ZDB-GENE-030429-1])

HSP 1 Score: 62.7734 bits (151), Expect = 2.164e-12
Identity = 33/80 (41.25%), Postives = 47/80 (58.75%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKN-IQFILRRS 400
            ME+KVW +G+ R VCG++E  +C +V++ LAQ    TG   L   + D E  L   + PL+ L K     N +QFILRR+
Sbjct:    1 MELKVWVDGIPRVVCGLSEDTSCQDVVIALAQAIGQTGRYVLIQKLRDKERQLMANECPLEALAKLGQLGNEVQFILRRT 80

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Zebrafish
Match: rassf8b (Ras association domain family member 8b [Source:ZFIN;Acc:ZDB-GENE-040426-1338])

HSP 1 Score: 65.0846 bits (157), Expect = 1.640e-11
Identity = 37/85 (43.53%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     + E  L P + P+  L K   Y SD  +Q +L+R+  S
Sbjct:    4 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRETERHLAPHENPVVSLNKWGQYASD--VQLVLQRTGPS 86

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Zebrafish
Match: rassf8b (Ras association domain family member 8b [Source:ZFIN;Acc:ZDB-GENE-040426-1338])

HSP 1 Score: 65.0846 bits (157), Expect = 1.788e-11
Identity = 37/85 (43.53%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     + E  L P + P+  L K   Y SD  +Q +L+R+  S
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRETERHLAPHENPVVSLNKWGQYASD--VQLVLQRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Zebrafish
Match: rassf7b (Ras association domain family member 7b [Source:ZFIN;Acc:ZDB-GENE-030429-1])

HSP 1 Score: 62.3882 bits (150), Expect = 2.984e-11
Identity = 33/80 (41.25%), Postives = 47/80 (58.75%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKN-IQFILRRS 400
            ME+KVW +G+ R VCG++E  +C +V++ LAQ    TG   L   + D E  L   + PL+ L K     N +QFILRR+
Sbjct:    1 MELKVWVDGIPRVVCGLSEDTSCQDVVIALAQAIGQTGRYVLIQKLRDKERQLMANECPLEALAKLGQLGNEVQFILRRT 80

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Xenopus
Match: foxc1 (forkhead box C1 [Source:Xenbase;Acc:XB-GENE-479055])

HSP 1 Score: 74.3294 bits (181), Expect = 1.693e-14
Identity = 38/85 (44.71%), Postives = 52/85 (61.18%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGV+E+ +C +V++ LAQ    TG   L   + D E  L P +RPL+ L K   Y +D  + FILRR+  S
Sbjct:    1 MELKVWVDGVQRVVCGVSEQTSCQDVVIALAQAIGQTGRYVLIQTLRDKERQLLPHERPLEFLSKSGQYAND--VHFILRRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Mouse
Match: Rassf8 (Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 [Source:MGI Symbol;Acc:MGI:1918573])

HSP 1 Score: 70.0922 bits (170), Expect = 3.822e-13
Identity = 40/85 (47.06%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P+  L K   Y SD  +Q ILRR+  S
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASD--VQLILRRTGPS 83

[Close]

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P+  L K   Y SD  +Q ILRR+  S
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASD--VQLILRRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Mouse
Match: Rassf7 (Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 [Source:MGI Symbol;Acc:MGI:1914235])

HSP 1 Score: 65.0846 bits (157), Expect = 5.805e-13
Identity = 34/85 (40.00%), Postives = 51/85 (60.00%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLD---ILKKYTSDKNIQFILRRSQNS 409
            ME+KVW +G+ R VCGV+E+ TC EV++ LAQ    TG   L   + + E  L PQ+ P+       ++ +D  +QF+LRR+  S
Sbjct:    8 MELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFAND--VQFVLRRTGPS 90

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Mouse
Match: Rassf8 (Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 [Source:MGI Symbol;Acc:MGI:1918573])

HSP 1 Score: 63.1586 bits (152), Expect = 1.291e-12
Identity = 39/81 (48.15%), Postives = 46/81 (56.79%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRR 397
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P+  L K   Y SD  +Q ILRR
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASD--VQLILRR 79

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Mouse
Match: Rassf7 (Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 [Source:MGI Symbol;Acc:MGI:1914235])

HSP 1 Score: 65.855 bits (159), Expect = 1.947e-12
Identity = 34/85 (40.00%), Postives = 51/85 (60.00%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLD---ILKKYTSDKNIQFILRRSQNS 409
            ME+KVW +G+ R VCGV+E+ TC EV++ LAQ    TG   L   + + E  L PQ+ P+       ++ +D  +QF+LRR+  S
Sbjct:    8 MELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFAND--VQFVLRRTGPS 90

[Close]

BLAST of Ras association domain family member 7a vs. UniProt/SwissProt
Match: sp|Q8NHQ8|RASF8_HUMAN (Ras association domain-containing protein 8 OS=Homo sapiens OX=9606 GN=RASSF8 PE=1 SV=2)

HSP 1 Score: 70.0922 bits (170), Expect = 2.413e-12
Identity = 40/85 (47.06%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P+  L K   Y SD  +Q ILRR+  S
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIISLNKWGQYASD--VQLILRRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. UniProt/SwissProt
Match: sp|Q8CJ96|RASF8_MOUSE (Ras association domain-containing protein 8 OS=Mus musculus OX=10090 GN=Rassf8 PE=2 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 2.674e-12
Identity = 40/85 (47.06%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P+  L K   Y SD  +Q ILRR+  S
Sbjct:    1 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRDTERHLAPHENPIVSLNKWGQYASD--VQLILRRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. UniProt/SwissProt
Match: sp|Q02833|RASF7_HUMAN (Ras association domain-containing protein 7 OS=Homo sapiens OX=9606 GN=RASSF7 PE=1 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 4.762e-12
Identity = 35/85 (41.18%), Postives = 51/85 (60.00%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLD---ILKKYTSDKNIQFILRRSQNS 409
            ME+KVW +G+ R VCGV+E+ TC EV++ LAQ    TG   L   + + E  L PQ+ P+       ++ SD  +QF+LRR+  S
Sbjct:    8 MELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASD--VQFVLRRTGPS 90

[Close]

BLAST of Ras association domain family member 7a vs. UniProt/SwissProt
Match: sp|Q9DD19|RASF7_MOUSE (Ras association domain-containing protein 7 OS=Mus musculus OX=10090 GN=Rassf7 PE=2 SV=2)

HSP 1 Score: 66.6254 bits (161), Expect = 2.964e-11
Identity = 34/87 (39.08%), Postives = 52/87 (59.77%), Query Frame = 2

Query:  158 LCMEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLD---ILKKYTSDKNIQFILRRSQNS 409
            + ME+KVW +G+ R VCGV+E+ TC EV++ LAQ    TG   L   + + E  L PQ+ P+       ++ +D  +QF+LRR+  S
Sbjct:    6 VAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFAND--VQFVLRRTGPS 90

[Close]

BLAST of Ras association domain family member 7a vs. TrEMBL
Match: A0A267GBX4 (Ras-associating domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017348g1 PE=4 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 3.186e-13
Identity = 60/223 (26.91%), Postives = 99/223 (44.39%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKNIQFILRRSQ----------------------------------------------NSENMYRKLKNHLAYQEQEIENNRLKLSEMDQEIMELQKSQLTNLSEEELMGIIKDQKEQIDLLEQVQWIDVVAEYRSKCRSLAADKTSLDGKIKEL 694
            ME+ +WFEG  R VC VT   +CH+VI+ +A+TA + G   L L   + E P+ P +     L +  + ++ + IL+R++                                               SEN+ R+LK  L  QE EIE NRL++ E+D+E+  L   QL+  S   L   +  Q+ ++  L Q    D +A+ R     L A++   D ++ ++
Sbjct:    1 MELNIWFEGQPRTVCNVTRDTSCHDVIMAVARTAGLPGRYTLVLRWPNGERPMAPNEPMAASLSR--APQHAELILQRTELTAAGQQHQQQPPQRQNNQLRPASLHTNGSGSSNCSTSSAEQLDAAASENVRRQLKQRLLMQEHEIEMNRLRIEELDKELRLL---QLSCQSAGSLEQRLHQQEAELQQLSQANLADCLAQERQLHDRLQAERRVWDKRLTDV 218

[Close]

BLAST of Ras association domain family member 7a vs. TrEMBL
Match: A0A267G9K8 (Ras-associating domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028266g2 PE=4 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 3.350e-13
Identity = 60/223 (26.91%), Postives = 99/223 (44.39%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKNIQFILRRSQ----------------------------------------------NSENMYRKLKNHLAYQEQEIENNRLKLSEMDQEIMELQKSQLTNLSEEELMGIIKDQKEQIDLLEQVQWIDVVAEYRSKCRSLAADKTSLDGKIKEL 694
            ME+ +WFEG  R VC VT   +CH+VI+ +A+TA + G   L L   + E P+ P +     L +  + ++ + IL+R++                                               SEN+ R+LK  L  QE EIE NRL++ E+D+E+  L   QL+  S   L   +  Q+ ++  L Q    D +A+ R     L A++   D ++ ++
Sbjct:    1 MELNIWFEGQPRTVCNVTRDTSCHDVIMAVARTAGLPGRYTLVLRWPNGERPMAPNEPMAASLSR--APQHAELILQRTELTAAGQQHQQQPPQRQNNQLRPASLDTNGSGSSNCSTSSAEQLDAAASENVRRQLKQRLLMQEHEIEMNRLRIEELDKELRLL---QLSCQSAGSLEQRLHQQEAELQQLSQANLADCLAQERQLHDRLQAERRVWDKRLTDV 218

[Close]

BLAST of Ras association domain family member 7a vs. TrEMBL
Match: A0A212EJM4 (Ras-associating domain-containing protein OS=Danaus plexippus plexippus OX=278856 GN=KGM_212488 PE=4 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 7.069e-13
Identity = 42/85 (49.41%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKN-IQFILRRSQNSEN 415
            ME+KVW EG+ R VCGVTE  TC +V+  LA      G   L     + E  L PQ+ PL IL K+    N IQFILRRS NS N
Sbjct:    1 MELKVWVEGIQRIVCGVTETTTCQDVVFALAHATGKVGRFTLIERWRNNERLLAPQEYPLKILMKWGEYSNDIQFILRRSDNSNN 85

[Close]

BLAST of Ras association domain family member 7a vs. TrEMBL
Match: S4NGZ0 (Ras-associating domain-containing protein (Fragment) OS=Pararge aegeria OX=116150 PE=4 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 1.162e-12
Identity = 41/85 (48.24%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKN-IQFILRRSQNSEN 415
            ME+KVW EG+ R VCGVTE  TC +V+  LA      G   L     + E  L PQ+ PL IL K+    N IQFILRRS N  N
Sbjct:    1 MELKVWVEGIQRIVCGVTETTTCQDVVFALAHATGKVGRFTLIERWRNNERLLAPQEYPLKILMKWGEYSNDIQFILRRSDNGSN 85

[Close]

BLAST of Ras association domain family member 7a vs. TrEMBL
Match: A0A194PLN7 (Ras association domain-containing protein 8 OS=Papilio xuthus OX=66420 GN=RR46_06693 PE=4 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 5.484e-12
Identity = 41/85 (48.24%), Postives = 49/85 (57.65%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKN-IQFILRRSQNSEN 415
            ME+KVW EG+ R VCGVTE  TC +V+  LA      G   L     + E  L PQ+ PL IL K+    N IQFILRRS +S N
Sbjct:    1 MELKVWVEGIQRIVCGVTETTTCQDVVFALAHATGKVGRFTLIERWRNNERLLAPQEYPLKILMKWGEYSNDIQFILRRSDSSSN 85

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Cavefish
Match: rassf8a (ras association domain-containing protein 8-like [Source:NCBI gene;Acc:103039191])

HSP 1 Score: 68.5514 bits (166), Expect = 8.754e-13
Identity = 37/85 (43.53%), Postives = 47/85 (55.29%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRP---LDILKKYTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D+E  L P + P   L+   +Y  D  +QF L R+  S
Sbjct:    1 MELKVWVDGVQRVVCGVTEATTCQEVVIALAQAIGRTGRYTLVEKWRDSERHLAPHESPVASLNTWGQYAGD--VQFFLHRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Cavefish
Match: rassf8a (ras association domain-containing protein 8-like [Source:NCBI gene;Acc:103039191])

HSP 1 Score: 68.5514 bits (166), Expect = 1.103e-12
Identity = 37/85 (43.53%), Postives = 47/85 (55.29%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRP---LDILKKYTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D+E  L P + P   L+   +Y  D  +QF L R+  S
Sbjct:    1 MELKVWVDGVQRVVCGVTEATTCQEVVIALAQAIGRTGRYTLVEKWRDSERHLAPHESPVASLNTWGQYAGD--VQFFLHRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Cavefish
Match: rassf8b (Ras association domain family member 8 [Source:NCBI gene;Acc:103033282])

HSP 1 Score: 64.6994 bits (156), Expect = 1.622e-11
Identity = 37/85 (43.53%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     + E  L P + P+  L K   Y SD  +Q +L+R+  S
Sbjct:    4 MELKVWVDGVQRIVCGVTEVTTCQEVVIALAQAIGRTGRYTLIEKWRETERYLAPHENPVVSLNKWGQYASD--VQLVLQRTGPS 86

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Cavefish
Match: rassf7b (ras association domain-containing protein 8-like [Source:NCBI gene;Acc:103046283])

HSP 1 Score: 63.1586 bits (152), Expect = 6.110e-11
Identity = 34/96 (35.42%), Postives = 53/96 (55.21%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTS-DKNIQFILRRSQNSENMYRKLKNHLAY 448
            ME+KVW +GV R VCG++++ +C +V++ LAQ    TG   L   + D E  L   + PL+ L K       +QFILRR+  + +    L  H ++
Sbjct:    1 MELKVWVDGVQRVVCGLSKETSCQDVVIALAQAIGQTGRYVLVQKLRDTERQLVADECPLESLSKLGQLSSEVQFILRRTGPTTSEGSDLDRHSSF 96

[Close]

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTS-DKNIQFILRRSQNSENMYRKLKNHLAY 448
            ME+KVW +GV R VCG++++ +C +V++ LAQ    TG   L   + D E  L   + PL+ L K       +QFILRR+  + +    L  H ++
Sbjct:    1 MELKVWVDGVQRVVCGLSKETSCQDVVIALAQAIGQTGRYVLVQKLRDTERQLVADECPLESLSKLGQLSSEVQFILRRTGPTTSEGSDLDRHSSF 96

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Sea Lamprey
Match: rassf8a (Ras association domain family member 8a [Source:ZFIN;Acc:ZDB-GENE-091014-4])

HSP 1 Score: 61.6178 bits (148), Expect = 4.303e-11
Identity = 33/80 (41.25%), Postives = 44/80 (55.00%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTS-DKNIQFILRRS 400
            ME+KVW EGV R VCGVT+  TCH+V++ LAQ    TG   L     D E  L P +     L  +     ++Q +LRR+
Sbjct:    1 MELKVWVEGVPRVVCGVTDATTCHDVVIALAQALGRTGRYTLIERWRDTERHLCPGESLAAALAAWGQHSADVQLLLRRT 80

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Nematostella
Match: EDO46381 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQK7])

HSP 1 Score: 46.595 bits (109), Expect = 4.304e-7
Identity = 25/77 (32.47%), Postives = 44/77 (57.14%), Query Frame = 2

Query:  167 EMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTS-DKNIQFILR 394
            E++VW +G  R + GV++  TC  +++ LA+ A  TG + L     D E  L   ++P+  L+ + S  K ++F+LR
Sbjct:    3 ELRVWVDGKERIIRGVSDSTTCESILIALAKAAGKTGRVALLEKWRDLERILPRTEKPIKCLQMWGSLQKEVKFLLR 79

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Medaka
Match: ENSORLT00000043406.1 (ras association domain-containing protein 8 [Source:NCBI gene;Acc:105354308])

HSP 1 Score: 67.3958 bits (163), Expect = 2.747e-12
Identity = 35/83 (42.17%), Postives = 48/83 (57.83%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSD-KNIQFILRRSQNS 409
            ME+KV+ +GV R VCGVT + TC EV+L LAQ     G   L     D E  + P +RPL+ L+KY    K +Q  L+ S ++
Sbjct:    1 MEVKVFVDGVPRVVCGVTRETTCQEVVLALAQAQGQPGRYILREKFKDFERCMTPDERPLETLEKYGEQAKEVQLTLQSSGST 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Medaka
Match: rassf8a (ras association domain-containing protein 8 [Source:NCBI gene;Acc:101155683])

HSP 1 Score: 65.855 bits (159), Expect = 7.260e-12
Identity = 36/85 (42.35%), Postives = 46/85 (54.12%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRP---LDILKKYTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     D E  L P + P   L+   +Y  D  +Q +L R+  S
Sbjct:    1 MELKVWVDGVQRVVCGVTEATTCQEVVIALAQAIGRTGRYTLVERWRDTERHLAPNESPVASLNTWGQYAGD--VQLVLHRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Medaka
Match: rassf8b (ras association domain-containing protein 8 [Source:NCBI gene;Acc:101160776])

HSP 1 Score: 65.4698 bits (158), Expect = 1.042e-11
Identity = 38/85 (44.71%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     + E  L P + P+  L K   Y SD  +Q IL+R+  S
Sbjct:    4 MELKVWVDGVQRIVCGVTEFTTCQEVVIALAQAIGRTGRYTLIEKWRETERHLAPHENPVVSLNKWGQYASD--VQLILQRTGPS 86

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Medaka
Match: rassf7a (ras association domain-containing protein 8 [Source:NCBI gene;Acc:101164772])

HSP 1 Score: 65.0846 bits (157), Expect = 1.515e-11
Identity = 33/83 (39.76%), Postives = 48/83 (57.83%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKN-IQFILRRSQNS 409
            ME+KVW +G +R VCG++E+ +C +V++ LAQ    TG   L   + D E  L   +RPL+ L K       +QF LRR+  S
Sbjct:    1 MELKVWVDGAVRVVCGLSEETSCQDVVIALAQAIGQTGRYVLIQRLRDTERQLLATERPLESLAKLGQHGGEVQFFLRRTGPS 83

[Close]

BLAST of Ras association domain family member 7a vs. Ensembl Medaka
Match: rassf8b (ras association domain-containing protein 8 [Source:NCBI gene;Acc:101160776])

HSP 1 Score: 64.6994 bits (156), Expect = 1.532e-11
Identity = 38/85 (44.71%), Postives = 48/85 (56.47%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKK---YTSDKNIQFILRRSQNS 409
            ME+KVW +GV R VCGVTE  TC EV++ LAQ    TG   L     + E  L P + P+  L K   Y SD  +Q IL+R+  S
Sbjct:    4 MELKVWVDGVQRIVCGVTEFTTCQEVVIALAQAIGRTGRYTLIEKWRETERHLAPHENPVVSLNKWGQYASD--VQLILQRTGPS 86

[Close]

BLAST of Ras association domain family member 7a vs. Planmine SMEST
Match: SMESG000080298.1 (SMESG000080298.1)

HSP 1 Score: 435.261 bits (1118), Expect = 1.503e-156
Identity = 211/212 (99.53%), Postives = 211/212 (99.53%), Query Frame = 2

Query:  164 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKNIQFILRRSQNSENMYRKLKNHLAYQEQEIENNRLKLSEMDQEIMELQKSQLTNLSEEELMGIIKDQKEQIDLLEQVQWIDVVAEYRSKCRSLAADKTSLDGKIKELESAIQAARTAHVELKKQLSRKPDSSQGRAPYGVWF 799
            MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKNIQFILRRSQNSENMYRKLKNHLAYQEQEIENNRLKLSEMDQEIMELQKSQLTNLSEEELMGIIKDQKEQ DLLEQVQWIDVVAEYRSKCRSLAADKTSLDGKIKELESAIQAARTAHVELKKQLSRKPDSSQGRAPYGVWF
Sbjct:    1 MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKNIQFILRRSQNSENMYRKLKNHLAYQEQEIENNRLKLSEMDQEIMELQKSQLTNLSEEELMGIIKDQKEQTDLLEQVQWIDVVAEYRSKCRSLAADKTSLDGKIKELESAIQAARTAHVELKKQLSRKPDSSQGRAPYGVWF 212

[Close]

BLAST of Ras association domain family member 7a vs. Planmine SMEST
Match: SMESG000080298.1 (SMESG000080298.1)

HSP 1 Score: 431.024 bits (1107), Expect = 5.753e-155
Identity = 209/210 (99.52%), Postives = 209/210 (99.52%), Query Frame = 2

Query:  170 MKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKNIQFILRRSQNSENMYRKLKNHLAYQEQEIENNRLKLSEMDQEIMELQKSQLTNLSEEELMGIIKDQKEQIDLLEQVQWIDVVAEYRSKCRSLAADKTSLDGKIKELESAIQAARTAHVELKKQLSRKPDSSQGRAPYGVWF 799
            MKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKNIQFILRRSQNSENMYRKLKNHLAYQEQEIENNRLKLSEMDQEIMELQKSQLTNLSEEELMGIIKDQKEQ DLLEQVQWIDVVAEYRSKCRSLAADKTSLDGKIKELESAIQAARTAHVELKKQLSRKPDSSQGRAPYGVWF
Sbjct:    1 MKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAEVPLHPQDRPLDILKKYTSDKNIQFILRRSQNSENMYRKLKNHLAYQEQEIENNRLKLSEMDQEIMELQKSQLTNLSEEELMGIIKDQKEQTDLLEQVQWIDVVAEYRSKCRSLAADKTSLDGKIKELESAIQAARTAHVELKKQLSRKPDSSQGRAPYGVWF 210

The following BLAST results are available for this feature:

BLAST of Ras association domain family member 7a vs. Ensembl Human
BLAST of Ras association domain family member 7a vs. Ensembl Celegans
BLAST of Ras association domain family member 7a vs. Ensembl Fly
BLAST of Ras association domain family member 7a vs. Ensembl Zebrafish
BLAST of Ras association domain family member 7a vs. Ensembl Xenopus
BLAST of Ras association domain family member 7a vs. Ensembl Mouse
BLAST of Ras association domain family member 7a vs. UniProt/SwissProt
BLAST of Ras association domain family member 7a vs. TrEMBL
BLAST of Ras association domain family member 7a vs. Ensembl Cavefish
BLAST of Ras association domain family member 7a vs. Ensembl Sea Lamprey
BLAST of Ras association domain family member 7a vs. Ensembl Yeast
BLAST of Ras association domain family member 7a vs. Ensembl Nematostella
BLAST of Ras association domain family member 7a vs. Ensembl Medaka
BLAST of Ras association domain family member 7a vs. Planmine SMEST

BLAST of Ras association domain family member 7a vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RASSF8	8.446e-14	47.06	Ras association domain family member 8 [Source:HGN...	[more]
RASSF8	1.116e-13	47.06	Ras association domain family member 8 [Source:HGN...	[more]
RASSF8	2.042e-13	47.06	Ras association domain family member 8 [Source:HGN...	[more]
RASSF8	2.069e-13	47.06	Ras association domain family member 8 [Source:HGN...	[more]
RASSF8	2.143e-13	47.06	Ras association domain family member 8 [Source:HGN...	[more]

BLAST of Ras association domain family member 7a vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
K05B2.2	6.172e-9	37.65	pep chromosome:WBcel235:X:4907290:4912323:1 gene:W...	[more]

BLAST of Ras association domain family member 7a vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
RASSF8	5.829e-12	41.46	gene:FBgn0261986 transcript:FBtr0084898	[more]

BLAST of Ras association domain family member 7a vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rassf8a	1.307e-13	44.94	Ras association domain family member 8a [Source:ZF...	[more]
rassf7b	2.164e-12	41.25	Ras association domain family member 7b [Source:ZF...	[more]
rassf8b	1.640e-11	43.53	Ras association domain family member 8b [Source:ZF...	[more]
rassf8b	1.788e-11	43.53	Ras association domain family member 8b [Source:ZF...	[more]
rassf7b	2.984e-11	41.25	Ras association domain family member 7b [Source:ZF...	[more]

BLAST of Ras association domain family member 7a vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
foxc1	1.693e-14	44.71	forkhead box C1 [Source:Xenbase;Acc:XB-GENE-479055...	[more]

BLAST of Ras association domain family member 7a vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rassf8	3.822e-13	47.06	Ras association (RalGDS/AF-6) domain family (N-ter...	[more]
Rassf8	3.822e-13	47.06	Ras association (RalGDS/AF-6) domain family (N-ter...	[more]
Rassf7	5.805e-13	40.00	Ras association (RalGDS/AF-6) domain family (N-ter...	[more]
Rassf8	1.291e-12	48.15	Ras association (RalGDS/AF-6) domain family (N-ter...	[more]
Rassf7	1.947e-12	40.00	Ras association (RalGDS/AF-6) domain family (N-ter...	[more]

BLAST of Ras association domain family member 7a vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4


Match Name	E-value	Identity	Description
sp\|Q8NHQ8\|RASF8_HUMAN	2.413e-12	47.06	Ras association domain-containing protein 8 OS=Hom...	[more]
sp\|Q8CJ96\|RASF8_MOUSE	2.674e-12	47.06	Ras association domain-containing protein 8 OS=Mus...	[more]
sp\|Q02833\|RASF7_HUMAN	4.762e-12	41.18	Ras association domain-containing protein 7 OS=Hom...	[more]
sp\|Q9DD19\|RASF7_MOUSE	2.964e-11	39.08	Ras association domain-containing protein 7 OS=Mus...	[more]

BLAST of Ras association domain family member 7a vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267GBX4	3.186e-13	26.91	Ras-associating domain-containing protein OS=Macro...	[more]
A0A267G9K8	3.350e-13	26.91	Ras-associating domain-containing protein OS=Macro...	[more]
A0A212EJM4	7.069e-13	49.41	Ras-associating domain-containing protein OS=Danau...	[more]
S4NGZ0	1.162e-12	48.24	Ras-associating domain-containing protein (Fragmen...	[more]
A0A194PLN7	5.484e-12	48.24	Ras association domain-containing protein 8 OS=Pap...	[more]

BLAST of Ras association domain family member 7a vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rassf8a	8.754e-13	43.53	ras association domain-containing protein 8-like [...	[more]
rassf8a	1.103e-12	43.53	ras association domain-containing protein 8-like [...	[more]
rassf8b	1.622e-11	43.53	Ras association domain family member 8 [Source:NCB...	[more]
rassf7b	6.110e-11	35.42	ras association domain-containing protein 8-like [...	[more]
rassf7b	6.110e-11	35.42	ras association domain-containing protein 8-like [...	[more]

BLAST of Ras association domain family member 7a vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
rassf8a	4.303e-11	41.25	Ras association domain family member 8a [Source:ZF...	[more]

BLAST of Ras association domain family member 7a vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Ras association domain family member 7a vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO46381	4.304e-7	32.47	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Ras association domain family member 7a vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000043406.1	2.747e-12	42.17	ras association domain-containing protein 8 [Sourc...	[more]
rassf8a	7.260e-12	42.35	ras association domain-containing protein 8 [Sourc...	[more]
rassf8b	1.042e-11	44.71	ras association domain-containing protein 8 [Sourc...	[more]
rassf7a	1.515e-11	39.76	ras association domain-containing protein 8 [Sourc...	[more]
rassf8b	1.532e-11	44.71	ras association domain-containing protein 8 [Sourc...	[more]

BLAST of Ras association domain family member 7a vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000080298.1	1.503e-156	99.53	SMESG000080298.1	[more]
SMESG000080298.1	5.753e-155	99.52	SMESG000080298.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30021652 ID=SMED30021652|Name=Ras association domain family member 7a|organism=Schmidtea mediterranea sexual|type=transcript|length=851bp
CACAAATTATATATTTAAAAACAAATTCTATTAAACTATTTAACTATTAT
TATCTGGAACTTAATATTTGACAGTTATTATTAGTAGTAAAGATCATTAA
ATTTAAAATTTTTATTCAATGAATATTTTATACGCTATCTAATAAATTAT
TATTATCCTTTGTATGGAAATGAAAGTTTGGTTTGAAGGAGTTTTAAGAG
ATGTTTGCGGTGTAACTGAAAAAAACACATGCCATGAAGTTATTTTAGTT
TTAGCGCAAACTGCAAGTATTACTGGCTCACTTTTCCTATCTTTAATTGT
AGATGATGCTGAAGTTCCTCTGCATCCTCAAGATCGCCCATTAGATATAT
TAAAAAAGTACACGTCAGACAAAAATATTCAATTTATTCTAAGAAGGTCA
CAGAACAGTGAAAATATGTACAGAAAATTAAAGAATCATTTGGCATATCA
AGAACAAGAAATTGAAAATAATCGCCTGAAACTTTCGGAAATGGATCAAG
AAATAATGGAGCTTCAAAAGTCTCAATTAACGAATCTCAGTGAAGAAGAA
CTGATGGGGATCATCAAAGATCAAAAAGAACAAATCGATTTATTGGAACA
AGTGCAATGGATCGATGTGGTAGCGGAATACCGGTCAAAATGCCGATCAC
TCGCTGCCGACAAGACGAGTCTCGATGGTAAAATCAAAGAGTTGGAGTCG
GCAATACAGGCGGCAAGAACTGCCCATGTAGAATTGAAGAAACAATTATC
AAGAAAACCCGATTCATCTCAGGGCCGTGCACCGTATGGCGTGTGGTTTT
AGTGTAGATAAATCTATGTGTGTATTATGGATATGCTCTGTCATTTTTAC
T

protein sequence of SMED30021652-orf-1

>SMED30021652-orf-1 ID=SMED30021652-orf-1|Name=SMED30021652-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=213bp
MEMKVWFEGVLRDVCGVTEKNTCHEVILVLAQTASITGSLFLSLIVDDAE
VPLHPQDRPLDILKKYTSDKNIQFILRRSQNSENMYRKLKNHLAYQEQEI
ENNRLKLSEMDQEIMELQKSQLTNLSEEELMGIIKDQKEQIDLLEQVQWI
DVVAEYRSKCRSLAADKTSLDGKIKELESAIQAARTAHVELKKQLSRKPD
SSQGRAPYGVWF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0070507	regulation of microtubule cytoskeleton organization
GO:0007165	signal transduction

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000101	muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR033593	N-RASSF
IPR000159	RA_dom
IPR029071	Ubiquitin-like_domsf

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 167..194
None	No IPR available	COILS	Coil	Coil	coord: 93..120
None	No IPR available	GENE3D	G3DSA:3.10.20.90		coord: 1..87 e-value: 7.4E-19 score: 69.3
None	No IPR available	PANTHER	PTHR15286:SF6	GH01133P	coord: 1..88
None	No IPR available	CDD	cd16134	RA_RASSF8	coord: 2..82 e-value: 1.66691E-20 score: 79.7876
IPR033593	N-terminal RASSF family	PANTHER	PTHR15286	RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN	coord: 1..88
IPR000159	Ras-associating (RA) domain	PROSITE	PS50200	RA	coord: 1..81 score: 9.405
IPR029071	Ubiquitin-like domain superfamily	SUPERFAMILY	SSF54236	Ubiquitin-like	coord: 1..81

Main menu

Ras association domain family member 7a

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

blazegraph-runner