eIF4E1-like protein

Overview


Name	eIF4E1-like protein (ACT98275.1)
Smed ID	SMED30021622
Length (bp)	858

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of eIF4E1-like protein (SMED30021622) t-SNE clustered cells

Violin plots show distribution of expression levels for eIF4E1-like protein (SMED30021622) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of eIF4E1-like protein (SMED30021622) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for eIF4E1-like protein (SMED30021622) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30021622

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
epidermis	SMED30021622	dd_Smed_v4_2919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30021622	dd_Smed_v4_2919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30021622	dd_Smed_v4_2919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
oocyte	SMED30021622	Contig19641	newmark_ests	PMID:28434803 Rouhana et al., 2017
oocyte	SMED30021622	Contig19641	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30021622	Contig19641	newmark_ests	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30021622	Contig19641	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
ovary	SMED30021622	PL030016A20B03	ncbi_smed_ests	PMID:28434803 Rouhana et al., 2017
testis	SMED30021622	PL030016A20B03	ncbi_smed_ests	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of eIF4E1-like protein vs. Ensembl Human
Match: EIF4E1B (eukaryotic translation initiation factor 4E family member 1B [Source:HGNC Symbol;Acc:HGNC:33179])

HSP 1 Score: 209.92 bits (533), Expect = 8.031e-67
Identity = 99/183 (54.10%), Postives = 124/183 (67.76%), Query Frame = 3

Query:  114 ELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            ELH LQN+W  +FFKNDRS+ W DN+  V   DTVEDFW L +HI   SKL SGCDY +FKD IQPMWED RNK GG WL++  K QR   LD  WLE L+ L+GE+FE+ S E+CGAVVNIR KGD+++VWT +  +   +  +G+  K+ LGL+    I Y AH D   KS+S AK  F +
Sbjct:   60 ELHPLQNRWALWFFKNDRSRAWQDNLHLVTKVDTVEDFWALYSHIQLASKLSSGCDYALFKDGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSREVCGAVVNIRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHADTATKSNSLAKNKFVV 242

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Query:  114 ELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            ELH LQN+W  +FFKNDRS+ W DN+  V   DTVEDFW L +HI   SKL SGCDY +FKD IQPMWED RNK GG WL++  K QR   LD  WLE L+ L+GE+FE+ S E+CGAVVNIR KGD+++VWT +  +   +  +G+  K+ LGL+    I Y AH D   KS+S AK  F +
Sbjct:   60 ELHPLQNRWALWFFKNDRSRAWQDNLHLVTKVDTVEDFWALYSHIQLASKLSSGCDYALFKDGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSREVCGAVVNIRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHADTATKSNSLAKNKFVV 242

[Close]

Query:  114 ELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            ELH LQN+W  +FFKNDRS+ W DN+  V   DTVEDFW L +HI   SKL SGCDY +FKD IQPMWED RNK GG WL++  K QR   LD  WLE L+ L+GE+FE+ S E+CGAVVNIR KGD+++VWT +  +   +  +G+  K+ LGL+    I Y AH D   KS+S AK  F +
Sbjct:   60 ELHPLQNRWALWFFKNDRSRAWQDNLHLVTKVDTVEDFWALYSHIQLASKLSSGCDYALFKDGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSREVCGAVVNIRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHADTATKSNSLAKNKFVV 242

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BLAST of eIF4E1-like protein vs. Ensembl Human
Match: EIF4E (eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287])

HSP 1 Score: 207.608 bits (527), Expect = 2.548e-66
Identity = 96/181 (53.04%), Postives = 125/181 (69.06%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L  GCDY +FKD I+PMWED++NK GG WL+T  K QR S LD  WLE L+ L+GE+F+D SD++CGAVVN+R KGD++++WTT+C + EA+  IG+  K+ LGL     I Y +H D   KS S  K  F +
Sbjct:   37 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 217

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Human
Match: EIF4E (eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:HGNC:3287])

HSP 1 Score: 207.994 bits (528), Expect = 3.693e-66
Identity = 96/181 (53.04%), Postives = 125/181 (69.06%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L  GCDY +FKD I+PMWED++NK GG WL+T  K QR S LD  WLE L+ L+GE+F+D SD++CGAVVN+R KGD++++WTT+C + EA+  IG+  K+ LGL     I Y +H D   KS S  K  F +
Sbjct:   57 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 237

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BLAST of eIF4E1-like protein vs. Ensembl Celegans
Match: ife-3 (Eukaryotic translation initiation factor 4E-3 [Source:UniProtKB/Swiss-Prot;Acc:O61955])

HSP 1 Score: 174.481 bits (441), Expect = 2.082e-53
Identity = 86/176 (48.86%), Postives = 113/176 (64.20%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAK 641
            H LQN+W  ++ K DR+K+W D +K V  FDTVEDFW L NHI     L  G DYY+FK+ I+PMWED  N  GG WL+  +K +R   LD  WLE+LM +VGE F++  D ICGAVVN+R KGD+VS+WT D +  +   RIGQ +K  L +  T  + Y  H D+  ++SS  K
Sbjct:   32 HPLQNRWALWYLKADRNKEWEDCLKMVSLFDTVEDFWSLYNHIQSAGGLNWGSDYYLFKEGIKPMWEDVNNVQGGRWLVVVDKQRRTQLLDHYWLELLMAIVGEQFDEYGDYICGAVVNVRQKGDKVSLWTRDATRDDVNLRIGQVLKQKLSIPDTEILRYEVHKDSSARTSSTVK 207

[Close]

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAK 641
            H LQN+W  ++ K DR+K+W D +K V  FDTVEDFW L NHI     L  G DYY+FK+ I+PMWED  N  GG WL+  +K +R   LD  WLE+LM +VGE F++  D ICGAVVN+R KGD+VS+WT D +  +   RIGQ +K  L +  T  + Y  H D+  ++SS  K
Sbjct:   32 HPLQNRWALWYLKADRNKEWEDCLKMVSLFDTVEDFWSLYNHIQSAGGLNWGSDYYLFKEGIKPMWEDVNNVQGGRWLVVVDKQRRTQLLDHYWLELLMAIVGEQFDEYGDYICGAVVNVRQKGDKVSLWTRDATRDDVNLRIGQVLKQKLSIPDTEILRYEVHKDSSARTSSTVK 207

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Celegans
Match: ife-3 (Eukaryotic translation initiation factor 4E-3 [Source:UniProtKB/Swiss-Prot;Acc:O61955])

HSP 1 Score: 169.474 bits (428), Expect = 1.831e-51
Identity = 86/178 (48.31%), Postives = 113/178 (63.48%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEK--NQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAK 641
            H LQN+W  ++ K DR+K+W D +K V  FDTVEDFW L NHI     L  G DYY+FK+ I+PMWED  N  GG WL+  +K   +R   LD  WLE+LM +VGE F++  D ICGAVVN+R KGD+VS+WT D +  +   RIGQ +K  L +  T  + Y  H D+  ++SS  K
Sbjct:   32 HPLQNRWALWYLKADRNKEWEDCLKMVSLFDTVEDFWSLYNHIQSAGGLNWGSDYYLFKEGIKPMWEDVNNVQGGRWLVVVDKQLQRRTQLLDHYWLELLMAIVGEQFDEYGDYICGAVVNVRQKGDKVSLWTRDATRDDVNLRIGQVLKQKLSIPDTEILRYEVHKDSSARTSSTVK 209

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Celegans
Match: ife-3 (Eukaryotic translation initiation factor 4E-3 [Source:UniProtKB/Swiss-Prot;Acc:O61955])

HSP 1 Score: 169.474 bits (428), Expect = 1.831e-51
Identity = 86/178 (48.31%), Postives = 113/178 (63.48%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEK--NQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAK 641
            H LQN+W  ++ K DR+K+W D +K V  FDTVEDFW L NHI     L  G DYY+FK+ I+PMWED  N  GG WL+  +K   +R   LD  WLE+LM +VGE F++  D ICGAVVN+R KGD+VS+WT D +  +   RIGQ +K  L +  T  + Y  H D+  ++SS  K
Sbjct:   32 HPLQNRWALWYLKADRNKEWEDCLKMVSLFDTVEDFWSLYNHIQSAGGLNWGSDYYLFKEGIKPMWEDVNNVQGGRWLVVVDKQLQRRTQLLDHYWLELLMAIVGEQFDEYGDYICGAVVNVRQKGDKVSLWTRDATRDDVNLRIGQVLKQKLSIPDTEILRYEVHKDSSARTSSTVK 209

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Celegans
Match: ife-3 (Eukaryotic translation initiation factor 4E-3 [Source:UniProtKB/Swiss-Prot;Acc:O61955])

HSP 1 Score: 169.474 bits (428), Expect = 2.415e-51
Identity = 86/179 (48.04%), Postives = 113/179 (63.13%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEK---NQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAK 641
            H LQN+W  ++ K DR+K+W D +K V  FDTVEDFW L NHI     L  G DYY+FK+ I+PMWED  N  GG WL+  +K    +R   LD  WLE+LM +VGE F++  D ICGAVVN+R KGD+VS+WT D +  +   RIGQ +K  L +  T  + Y  H D+  ++SS  K
Sbjct:   32 HPLQNRWALWYLKADRNKEWEDCLKMVSLFDTVEDFWSLYNHIQSAGGLNWGSDYYLFKEGIKPMWEDVNNVQGGRWLVVVDKQKLQRRTQLLDHYWLELLMAIVGEQFDEYGDYICGAVVNVRQKGDKVSLWTRDATRDDVNLRIGQVLKQKLSIPDTEILRYEVHKDSSARTSSTVK 210

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Fly
Match: eIF4E1 (gene:FBgn0015218 transcript:FBtr0076488)

HSP 1 Score: 183.341 bits (464), Expect = 9.876e-57
Identity = 86/181 (47.51%), Postives = 119/181 (65.75%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDA--LGLTCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H L N WT ++ +NDRSK W D   ++  FDTVEDFW L NHI PPS++  G DY +FK  I+PMWED  NK GG W++T  K+ + + LD  WL++L+ L+GE F D SD+ICGAV+NIRGK +++S+WT D ++ EA   IG K++DA  LG   +++Y  H D   K  S  K  + +
Sbjct:   70 HPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSK-TDLDNLWLDVLLCLIGEAF-DHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL 248

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Fly
Match: eIF4E1 (gene:FBgn0015218 transcript:FBtr0076493)

HSP 1 Score: 182.956 bits (463), Expect = 1.642e-56
Identity = 86/181 (47.51%), Postives = 119/181 (65.75%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDA--LGLTCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H L N WT ++ +NDRSK W D   ++  FDTVEDFW L NHI PPS++  G DY +FK  I+PMWED  NK GG W++T  K+ + + LD  WL++L+ L+GE F D SD+ICGAV+NIRGK +++S+WT D ++ EA   IG K++DA  LG   +++Y  H D   K  S  K  + +
Sbjct:   81 HPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSK-TDLDNLWLDVLLCLIGEAF-DHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL 259

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Fly
Match: eIF4E1 (gene:FBgn0015218 transcript:FBtr0076489)

HSP 1 Score: 182.956 bits (463), Expect = 1.642e-56
Identity = 86/181 (47.51%), Postives = 119/181 (65.75%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDA--LGLTCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H L N WT ++ +NDRSK W D   ++  FDTVEDFW L NHI PPS++  G DY +FK  I+PMWED  NK GG W++T  K+ + + LD  WL++L+ L+GE F D SD+ICGAV+NIRGK +++S+WT D ++ EA   IG K++DA  LG   +++Y  H D   K  S  K  + +
Sbjct:   81 HPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSK-TDLDNLWLDVLLCLIGEAF-DHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL 259

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Fly
Match: eIF4E1 (gene:FBgn0015218 transcript:FBtr0076490)

HSP 1 Score: 182.956 bits (463), Expect = 1.642e-56
Identity = 86/181 (47.51%), Postives = 119/181 (65.75%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDA--LGLTCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H L N WT ++ +NDRSK W D   ++  FDTVEDFW L NHI PPS++  G DY +FK  I+PMWED  NK GG W++T  K+ + + LD  WL++L+ L+GE F D SD+ICGAV+NIRGK +++S+WT D ++ EA   IG K++DA  LG   +++Y  H D   K  S  K  + +
Sbjct:   81 HPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSK-TDLDNLWLDVLLCLIGEAF-DHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL 259

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Fly
Match: eIF4E1 (gene:FBgn0015218 transcript:FBtr0076487)

HSP 1 Score: 182.956 bits (463), Expect = 1.642e-56
Identity = 86/181 (47.51%), Postives = 119/181 (65.75%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDA--LGLTCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H L N WT ++ +NDRSK W D   ++  FDTVEDFW L NHI PPS++  G DY +FK  I+PMWED  NK GG W++T  K+ + + LD  WL++L+ L+GE F D SD+ICGAV+NIRGK +++S+WT D ++ EA   IG K++DA  LG   +++Y  H D   K  S  K  + +
Sbjct:   81 HPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSK-TDLDNLWLDVLLCLIGEAF-DHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL 259

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Zebrafish
Match: eif4e1c (eukaryotic translation initiation factor 4E family member 1c [Source:ZFIN;Acc:ZDB-GENE-050417-398])

HSP 1 Score: 206.068 bits (523), Expect = 6.603e-66
Identity = 93/181 (51.38%), Postives = 128/181 (70.72%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCA--IEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  ++FKND+SK W +N++ +  FDTVEDFW L NHI  PSKL  GCDY +FKD I+PMWEDDRNK GG WL+T  K QR + LD  W+E L+ L+GE+F++ S+++CGAVVN+R KGD++++WT +C + +AI  IGQ+ K+ L L     I Y +H D  +KS S  K  + +
Sbjct:   33 HPLQNRWALWYFKNDKSKSWTENLRLISKFDTVEDFWALYNHIQQPSKLGFGCDYCLFKDGIKPMWEDDRNKLGGRWLMTLSKQQRHNDLDRYWMETLLCLIGESFDEASEDVCGAVVNVRPKGDKIAIWTGNCQNRDAIMTIGQQYKERLSLPSKTLIGYQSHDDTSSKSGSTTKNMYSV 213

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Zebrafish
Match: eif4e1c (eukaryotic translation initiation factor 4E family member 1c [Source:ZFIN;Acc:ZDB-GENE-050417-398])

HSP 1 Score: 206.068 bits (523), Expect = 8.527e-66
Identity = 93/181 (51.38%), Postives = 128/181 (70.72%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCA--IEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  ++FKND+SK W +N++ +  FDTVEDFW L NHI  PSKL  GCDY +FKD I+PMWEDDRNK GG WL+T  K QR + LD  W+E L+ L+GE+F++ S+++CGAVVN+R KGD++++WT +C + +AI  IGQ+ K+ L L     I Y +H D  +KS S  K  + +
Sbjct:   50 HPLQNRWALWYFKNDKSKSWTENLRLISKFDTVEDFWALYNHIQQPSKLGFGCDYCLFKDGIKPMWEDDRNKLGGRWLMTLSKQQRHNDLDRYWMETLLCLIGESFDEASEDVCGAVVNVRPKGDKIAIWTGNCQNRDAIMTIGQQYKERLSLPSKTLIGYQSHDDTSSKSGSTTKNMYSV 230

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BLAST of eIF4E1-like protein vs. Ensembl Zebrafish
Match: eif4e1c (eukaryotic translation initiation factor 4E family member 1c [Source:ZFIN;Acc:ZDB-GENE-050417-398])

HSP 1 Score: 206.068 bits (523), Expect = 8.527e-66
Identity = 93/181 (51.38%), Postives = 128/181 (70.72%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCA--IEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  ++FKND+SK W +N++ +  FDTVEDFW L NHI  PSKL  GCDY +FKD I+PMWEDDRNK GG WL+T  K QR + LD  W+E L+ L+GE+F++ S+++CGAVVN+R KGD++++WT +C + +AI  IGQ+ K+ L L     I Y +H D  +KS S  K  + +
Sbjct:   50 HPLQNRWALWYFKNDKSKSWTENLRLISKFDTVEDFWALYNHIQQPSKLGFGCDYCLFKDGIKPMWEDDRNKLGGRWLMTLSKQQRHNDLDRYWMETLLCLIGESFDEASEDVCGAVVNVRPKGDKIAIWTGNCQNRDAIMTIGQQYKERLSLPSKTLIGYQSHDDTSSKSGSTTKNMYSV 230

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BLAST of eIF4E1-like protein vs. Ensembl Zebrafish
Match: eif4ea (eukaryotic translation initiation factor 4ea [Source:NCBI gene;Acc:79380])

HSP 1 Score: 205.297 bits (521), Expect = 1.185e-65
Identity = 98/181 (54.14%), Postives = 124/181 (68.51%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L SGCDY +FKD I+PMWED+RNK GG WL+T  K QR + LD  WLE L+ LVGE F+D SD++CGAVVNIR KGD++++WTTD  + +AI  IG+  K+ LG+     I Y +H D   KS S  K  F +
Sbjct:   35 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDERNKRGGRWLITLSKQQRRADLDRFWLETLLCLVGEAFDDHSDDVCGAVVNIRTKGDKIAIWTTDYENKDAIVHIGRVYKERLGVPPKVIIGYQSHADTATKSGSTTKNKFVV 215

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BLAST of eIF4E1-like protein vs. Ensembl Zebrafish
Match: eif4ea (eukaryotic translation initiation factor 4ea [Source:NCBI gene;Acc:79380])

HSP 1 Score: 205.297 bits (521), Expect = 1.279e-65
Identity = 98/181 (54.14%), Postives = 124/181 (68.51%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L SGCDY +FKD I+PMWED+RNK GG WL+T  K QR + LD  WLE L+ LVGE F+D SD++CGAVVNIR KGD++++WTTD  + +AI  IG+  K+ LG+     I Y +H D   KS S  K  F +
Sbjct:   35 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDERNKRGGRWLITLSKQQRRADLDRFWLETLLCLVGEAFDDHSDDVCGAVVNIRTKGDKIAIWTTDYENKDAIVHIGRVYKERLGVPPKVIIGYQSHADTATKSGSTTKNKFVV 215

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BLAST of eIF4E1-like protein vs. Ensembl Xenopus
Match: ENSXETT00000049404.1 (eukaryotic translation initiation factor 4E family member 1B [Source:NCBI gene;Acc:100127761])

HSP 1 Score: 203.371 bits (516), Expect = 9.077e-65
Identity = 94/181 (51.93%), Postives = 124/181 (68.51%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQ++W  +FFKN +S+ W  N++ V  F+TVEDFW L  HI   SKL SGCDY +FKD I+PMWED RNK GG WL+T  K QR S LD  WLE L+ L+GE F++ S+E+CGAV+NIR KGD++++WT +  + EA+  IG+  K+ LGL+    I Y AH D   KSSS +K  F +
Sbjct:   37 HSLQSRWALWFFKNVKSQPWQCNLRLVTTFNTVEDFWSLYTHIQLASKLSSGCDYSLFKDGIEPMWEDSRNKRGGRWLITLSKQQRHSDLDALWLETLLCLIGEAFDEYSEEVCGAVINIRAKGDKIAIWTRETENREAVTHIGKVYKERLGLSSKVVIGYQAHADTATKSSSLSKNKFVV 217

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BLAST of eIF4E1-like protein vs. Ensembl Xenopus
Match: snx1 (sorting nexin 1 [Source:Xenbase;Acc:XB-GENE-992259])

HSP 1 Score: 203.371 bits (516), Expect = 1.024e-64
Identity = 94/181 (51.93%), Postives = 125/181 (69.06%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTC--AIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L SGCDY +FKD I+PMWED++NK GG WL+T  K QR + LD  WLE LM L+GE+F++ SD++CGAVVN+R KGD++++WTT+  + +A+  IG+  K+ LGL     I Y +H D   KS S  K  F +
Sbjct:   36 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRNDLDRFWLETLMCLIGESFDEYSDDVCGAVVNVRAKGDKIAIWTTEFENRDAVTHIGKVYKERLGLPAKVVIGYQSHADTATKSGSTTKNRFVV 216

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BLAST of eIF4E1-like protein vs. Ensembl Xenopus
Match: ENSXETT00000049401.1 (eukaryotic translation initiation factor 4E family member 1B [Source:NCBI gene;Acc:100127761])

HSP 1 Score: 202.986 bits (515), Expect = 2.120e-64
Identity = 94/181 (51.93%), Postives = 124/181 (68.51%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQ++W  +FFKN +S+ W  N++ V  F+TVEDFW L  HI   SKL SGCDY +FKD I+PMWED RNK GG WL+T  K QR S LD  WLE L+ L+GE F++ S+E+CGAV+NIR KGD++++WT +  + EA+  IG+  K+ LGL+    I Y AH D   KSSS +K  F +
Sbjct:   46 HSLQSRWALWFFKNVKSQPWQCNLRLVTTFNTVEDFWSLYTHIQLASKLSSGCDYSLFKDGIEPMWEDSRNKRGGRWLITLSKQQRHSDLDALWLETLLCLIGEAFDEYSEEVCGAVINIRAKGDKIAIWTRETENREAVTHIGKVYKERLGLSSKVVIGYQAHADTATKSSSLSKNKFVV 226

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BLAST of eIF4E1-like protein vs. Ensembl Xenopus
Match: snx1 (sorting nexin 1 [Source:Xenbase;Acc:XB-GENE-992259])

HSP 1 Score: 204.142 bits (518), Expect = 6.522e-64
Identity = 94/181 (51.93%), Postives = 125/181 (69.06%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTC--AIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L SGCDY +FKD I+PMWED++NK GG WL+T  K QR + LD  WLE LM L+GE+F++ SD++CGAVVN+R KGD++++WTT+  + +A+  IG+  K+ LGL     I Y +H D   KS S  K  F +
Sbjct:  125 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRNDLDRFWLETLMCLIGESFDEYSDDVCGAVVNVRAKGDKIAIWTTEFENRDAVTHIGKVYKERLGLPAKVVIGYQSHADTATKSGSTTKNRFVV 305

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BLAST of eIF4E1-like protein vs. Ensembl Xenopus
Match: txnrd1 (thioredoxin reductase 1 [Source:Xenbase;Acc:XB-GENE-956002])

HSP 1 Score: 113.62 bits (283), Expect = 3.009e-30
Identity = 59/172 (34.30%), Postives = 93/172 (54.07%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKND-----RSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDA 614
            H LQ  +TF++ +        S+ +  N+K++  F +VE FW   +H+  P  L    D+++FK+ I+PMWEDD NKNGG W++   K         CW  +++ ++GE F    +EICGAVV++R + D +S+W    S      RI   ++  L L     +EY  HTD+
Sbjct:   18 HPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGL----ASRCWENLILAMLGEQFM-VGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTVMEYKTHTDS 184

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BLAST of eIF4E1-like protein vs. Ensembl Mouse
Match: Eif4e (eukaryotic translation initiation factor 4E [Source:MGI Symbol;Acc:MGI:95305])

HSP 1 Score: 206.068 bits (523), Expect = 7.919e-66
Identity = 95/181 (52.49%), Postives = 125/181 (69.06%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L  GCDY +FKD I+PMWED++NK GG WL+T  K QR S LD  WLE L+ L+GE+F+D SD++CGAVVN+R KGD++++WTT+C + +A+  IG+  K+ LGL     I Y +H D   KS S  K  F +
Sbjct:   37 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 217

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BLAST of eIF4E1-like protein vs. Ensembl Mouse
Match: Eif4e1b (eukaryotic translation initiation factor 4E family member 1B [Source:MGI Symbol;Acc:MGI:2685119])

HSP 1 Score: 190.274 bits (482), Expect = 2.060e-59
Identity = 91/178 (51.12%), Postives = 121/178 (67.98%), Query Frame = 3

Query:  111 SELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCA--IEYTAHTDAQNKSSSRA 638
            S+LH LQ +W  +FFKNDRS+ W DN++ V  F+TVEDFW + +HI   SKL SGCDY +FK+ I PMWED+RNK GG WLL+ +K  R   LD  WLE L+ LVG  FE+ S E+CGAVVNIR K D++++WT++      + +IGQ  K+ LG++    I Y AH D   KS++ A
Sbjct:   62 SKLHPLQYRWVLWFFKNDRSRAWQDNLQLVTKFNTVEDFWAVYSHIKLASKLSSGCDYALFKEGILPMWEDNRNKQGGRWLLSIDKQLRHFELDRLWLETLLCLVGNCFEEYSREVCGAVVNIRTKRDKIALWTSEAEDKAGVMQIGQIYKERLGISTKTIIGYQAHADTAAKSNNLA 239

[Close]

Query:  111 SELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCA--IEYTAHTDAQNKSSSRA 638
            S+LH LQ +W  +FFKNDRS+ W DN++ V  F+TVEDFW + +HI   SKL SGCDY +FK+ I PMWED+RNK GG WLL+ +K  R   LD  WLE L+ LVG  FE+ S E+CGAVVNIR K D++++WT++      + +IGQ  K+ LG++    I Y AH D   KS++ A
Sbjct:   62 SKLHPLQYRWVLWFFKNDRSRAWQDNLQLVTKFNTVEDFWAVYSHIKLASKLSSGCDYALFKEGILPMWEDNRNKQGGRWLLSIDKQLRHFELDRLWLETLLCLVGNCFEEYSREVCGAVVNIRTKRDKIALWTSEAEDKAGVMQIGQIYKERLGISTKTIIGYQAHADTAAKSNNLA 239

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Mouse
Match: Eif4e1b (eukaryotic translation initiation factor 4E family member 1B [Source:MGI Symbol;Acc:MGI:2685119])

HSP 1 Score: 190.66 bits (483), Expect = 2.191e-59
Identity = 91/178 (51.12%), Postives = 121/178 (67.98%), Query Frame = 3

Query:  111 SELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCA--IEYTAHTDAQNKSSSRA 638
            S+LH LQ +W  +FFKNDRS+ W DN++ V  F+TVEDFW + +HI   SKL SGCDY +FK+ I PMWED+RNK GG WLL+ +K  R   LD  WLE L+ LVG  FE+ S E+CGAVVNIR K D++++WT++      + +IGQ  K+ LG++    I Y AH D   KS++ A
Sbjct:   68 SKLHPLQYRWVLWFFKNDRSRAWQDNLQLVTKFNTVEDFWAVYSHIKLASKLSSGCDYALFKEGILPMWEDNRNKQGGRWLLSIDKQLRHFELDRLWLETLLCLVGNCFEEYSREVCGAVVNIRTKRDKIALWTSEAEDKAGVMQIGQIYKERLGISTKTIIGYQAHADTAAKSNNLA 245

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Mouse
Match: Eif4e (eukaryotic translation initiation factor 4E [Source:MGI Symbol;Acc:MGI:95305])

HSP 1 Score: 187.578 bits (475), Expect = 3.825e-59
Identity = 82/145 (56.55%), Postives = 109/145 (75.17%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQ 554
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L  GCDY +FKD I+PMWED++NK GG WL+T  K QR S LD  WLE L+ L+GE+F+D SD++CGAVVN+R KGD++++WTT+C + +A+  IG+
Sbjct:   37 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGR 181

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BLAST of eIF4E1-like protein vs. UniProt/SwissProt
Match: sp|O77210|IF4E_APLCA (Eukaryotic translation initiation factor 4E OS=Aplysia californica OX=6500 PE=1 SV=1)

HSP 1 Score: 211.46 bits (537), Expect = 3.869e-67
Identity = 98/181 (54.14%), Postives = 124/181 (68.51%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN W  +FFKND+S+DW DN++ +  FDTVEDFWGL NH  P SKL SGCDY VFK  IQPMWED +NK GG WL+   K QR +HLD  WLE L+ L+GE F++ S+EICGA VNIR KGD++ +WT D    EA K+IG K+K++L +     I + AH+D   K+ S  K  F +
Sbjct:   35 HPLQNSWAMWFFKNDKSRDWKDNLRVITTFDTVEDFWGLYNHTLPASKLQSGCDYSVFKAGIQPMWEDAQNKKGGRWLINLNKTQRQTHLDDFWLETLLCLIGEGFDEHSEEICGATVNIRNKGDKLGLWTRDAQKTEATKKIGIKLKESLSVPPKIVIGFQAHSDTAGKAGSTVKNRFTV 215

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BLAST of eIF4E1-like protein vs. UniProt/SwissProt
Match: sp|A6NMX2|I4E1B_HUMAN (Eukaryotic translation initiation factor 4E type 1B OS=Homo sapiens OX=9606 GN=EIF4E1B PE=1 SV=3)

HSP 1 Score: 209.92 bits (533), Expect = 3.857e-66
Identity = 99/183 (54.10%), Postives = 124/183 (67.76%), Query Frame = 3

Query:  114 ELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            ELH LQN+W  +FFKNDRS+ W DN+  V   DTVEDFW L +HI   SKL SGCDY +FKD IQPMWED RNK GG WL++  K QR   LD  WLE L+ L+GE+FE+ S E+CGAVVNIR KGD+++VWT +  +   +  +G+  K+ LGL+    I Y AH D   KS+S AK  F +
Sbjct:   60 ELHPLQNRWALWFFKNDRSRAWQDNLHLVTKVDTVEDFWALYSHIQLASKLSSGCDYALFKDGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSREVCGAVVNIRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHADTATKSNSLAKNKFVV 242

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BLAST of eIF4E1-like protein vs. UniProt/SwissProt
Match: sp|P06730|IF4E_HUMAN (Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2)

HSP 1 Score: 207.608 bits (527), Expect = 1.224e-65
Identity = 96/181 (53.04%), Postives = 125/181 (69.06%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L  GCDY +FKD I+PMWED++NK GG WL+T  K QR S LD  WLE L+ L+GE+F+D SD++CGAVVN+R KGD++++WTT+C + EA+  IG+  K+ LGL     I Y +H D   KS S  K  F +
Sbjct:   37 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 217

[Close]

BLAST of eIF4E1-like protein vs. UniProt/SwissProt
Match: sp|Q9N0T5|IF4E_BOVIN (Eukaryotic translation initiation factor 4E OS=Bos taurus OX=9913 GN=EIF4E PE=2 SV=2)

HSP 1 Score: 206.453 bits (524), Expect = 3.587e-65
Identity = 95/181 (52.49%), Postives = 125/181 (69.06%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L  GCDY +FKD I+PMWED++NK GG WL+T  K QR S LD  WLE ++ L+GE+F+D SD++CGAVVN+R KGD++++WTT+C + EA+  IG+  K+ LGL     I Y +H D   KS S  K  F +
Sbjct:   37 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETVLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 217

[Close]

BLAST of eIF4E1-like protein vs. UniProt/SwissProt
Match: sp|P63074|IF4E_RAT (Eukaryotic translation initiation factor 4E OS=Rattus norvegicus OX=10116 GN=Eif4e PE=1 SV=1)

HSP 1 Score: 206.068 bits (523), Expect = 5.539e-65
Identity = 95/181 (52.49%), Postives = 125/181 (69.06%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L  GCDY +FKD I+PMWED++NK GG WL+T  K QR S LD  WLE L+ L+GE+F+D SD++CGAVVN+R KGD++++WTT+C + +A+  IG+  K+ LGL     I Y +H D   KS S  K  F +
Sbjct:   37 HPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV 217

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BLAST of eIF4E1-like protein vs. TrEMBL
Match: D2DJT8 (eIF4E1-like protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 326.635 bits (836), Expect = 5.322e-111
Identity = 156/156 (100.00%), Postives = 156/156 (100.00%), Query Frame = 3

Query:  189 MKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDAQNKSSSRAKCTFRI 656
            MKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDAQNKSSSRAKCTFRI
Sbjct:    1 MKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDAQNKSSSRAKCTFRI 156

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BLAST of eIF4E1-like protein vs. TrEMBL
Match: D5JG41 (Eukaryotic initiation factor-4E (Fragment) OS=Dugesia japonica OX=6161 GN=eIF4E PE=2 SV=1)

HSP 1 Score: 308.145 bits (788), Expect = 8.445e-103
Identity = 157/208 (75.48%), Postives = 181/208 (87.02%), Query Frame = 3

Query:   18 EMVDETSLGXXXXXXXXXXXXXXXXXXXAGDSELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDAQNKSSSRAK 641
            EMV++ SL +L NLKLE +DN EN  +LA D++LHYL+NKW FYFFK DRSKDWIDNMKKVIDFDTVE FWGL+N+IAPPSKLP+GCDYY+FKDVIQPMWED+RNKNGGM +L F+K + IS+LD CWLEILMLLVGETFEDDS+EICGAV N RGKGDR+SVW T+CSS E IKRIG KIKDALGL C++EY AH DA+  S+SRAK
Sbjct:    1 EMVEKASLVDLVNLKLEGDDNFENNNTLAPDTDLHYLENKWAFYFFKYDRSKDWIDNMKKVIDFDTVEGFWGLVNYIAPPSKLPNGCDYYIFKDVIQPMWEDERNKNGGMCILPFDKRENISYLDSCWLEILMLLVGETFEDDSEEICGAVFNKRGKGDRISVWXTNCSSTEPIKRIGNKIKDALGLRCSVEYVAHADAKKMSNSRAK 208

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BLAST of eIF4E1-like protein vs. TrEMBL
Match: A0A1W6I191 (Translation initiation factor 4E-like protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 283.108 bits (723), Expect = 1.155e-93
Identity = 156/159 (98.11%), Postives = 156/159 (98.11%), Query Frame = 3

Query:   21 MVDETSLGXXXXXXXXXXXXXXXXXXXAGDSELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDR 497
            MVDETSLGNLSNLKLEDEDNEENLKSLAGDSELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDS EICGAV  IRGKGDR
Sbjct:    1 MVDETSLGNLSNLKLEDEDNEENLKSLAGDSELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSXEICGAVAXIRGKGDR 159

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BLAST of eIF4E1-like protein vs. TrEMBL
Match: K1PGU1 (Eukaryotic translation initiation factor 4E OS=Crassostrea gigas OX=29159 GN=CGI_10000487 PE=3 SV=1)

HSP 1 Score: 218.009 bits (554), Expect = 1.080e-67
Identity = 98/181 (54.14%), Postives = 133/181 (73.48%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIE--YTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKNDR+K+W  N+K +  FDTVEDFW L NH+   SKLPSGCDY +FKD +QPMWED+RNK+GG WL+   KNQR++ LD  WLE L+ L+GE+FE+ S++ICGAVVNIR KGD++S+WT +    +AI +IG+K+K+ L +   I+  + +H D   K+ S AK  FR+
Sbjct:    9 HPLQNRWALWFFKNDRNKEWTANLKLITAFDTVEDFWALYNHVQKASKLPSGCDYSLFKDGVQPMWEDERNKDGGRWLINLNKNQRMTDLDNFWLETLLCLIGESFEEYSEDICGAVVNIRNKGDKLSLWTKEAGRPDAILKIGRKLKERLSIPAKIQIGFQSHRDTMTKTGSTAKDRFRV 189

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BLAST of eIF4E1-like protein vs. TrEMBL
Match: A0A210PSB7 (Eukaryotic translation initiation factor 4E OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT05288 PE=3 SV=1)

HSP 1 Score: 218.779 bits (556), Expect = 1.664e-67
Identity = 102/181 (56.35%), Postives = 132/181 (72.93%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQNKW  +FFKNDR+K+W  N+K V  FDTVEDFW L NH+   SKLPSGCDY +FKD IQPMWED +NK+GG WL+   K QR S LD  WLE L+ L+GE+FE+ SD++ GAVVN+R KGD++S+WT D +  +AI +IG+K+KD+L +    AI + AHTD   K+ S A+  FR+
Sbjct:   36 HPLQNKWALWFFKNDRTKEWTANLKLVTSFDTVEDFWALYNHVQKASKLPSGCDYSLFKDGIQPMWEDAQNKDGGRWLINLNKQQRHSDLDNFWLETLLCLIGESFEEFSDDVNGAVVNVRNKGDKLSLWTRDATRPDAIMKIGKKLKDSLKIPIKIAIGFQAHTDTMTKTGSTARDRFRV 216

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BLAST of eIF4E1-like protein vs. Ensembl Cavefish
Match: eif4ea (eukaryotic translation initiation factor 4E-1A [Source:NCBI gene;Acc:103043705])

HSP 1 Score: 204.527 bits (519), Expect = 1.943e-65
Identity = 99/181 (54.70%), Postives = 123/181 (67.96%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L SGCDY +FKD I+PMWED+RNK GG WL+T  K QR + LD  WLE L+ LVGE F+D SD++CGAVVNIR KGD++S+WTTD  + +AI  IG+  K  LG+     I Y +H D   KS S  K  F +
Sbjct:   38 HPLQNRWALWFFKNDKSKTWQANLQLISKFDTVEDFWALYNHIQLSSNLISGCDYSLFKDGIEPMWEDERNKKGGRWLITLSKQQRRADLDRFWLETLLCLVGEAFDDHSDDVCGAVVNIRTKGDKISIWTTDYENKDAIVHIGRVYKARLGVPPKVIIGYQSHADTATKSGSTTKNKFVV 218

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BLAST of eIF4E1-like protein vs. Ensembl Cavefish
Match: eif4e1c (eukaryotic translation initiation factor 4E-like [Source:NCBI gene;Acc:103032634])

HSP 1 Score: 202.601 bits (514), Expect = 1.100e-64
Identity = 92/181 (50.83%), Postives = 127/181 (70.17%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCA--IEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  ++FKND+SK W +N++ +  FDTVEDFW L NHI  PSKL  GCDY +FKD I+PMWEDDRNK GG WL+T  K QR + LD  W+E L+ L+GE+F++ S+++CGAVVN+R KGD++++WT +C + +AI  IG + K+ L L     I Y +H D  +KS S  K  + +
Sbjct:   30 HPLQNRWALWYFKNDKSKSWTENLRLISKFDTVEDFWALYNHIQQPSKLGFGCDYCLFKDGIKPMWEDDRNKLGGRWLMTLSKQQRHNDLDRYWMETLLCLIGESFDEASEDVCGAVVNVRPKGDKIAIWTGNCQNRDAIMTIGLQYKERLNLPIKTLIGYQSHDDTSSKSGSTTKNMYSV 210

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BLAST of eIF4E1-like protein vs. Ensembl Cavefish
Match: eif4eb (eukaryotic translation initiation factor 4E-1A [Source:NCBI gene;Acc:103043156])

HSP 1 Score: 201.83 bits (512), Expect = 3.809e-64
Identity = 96/181 (53.04%), Postives = 123/181 (67.96%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALG--LTCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W+ +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L SGCDY +FKD I+PMWED+RNK GG WL+T  K QR   LD  WLE L+ L+GE F+D SD++CGAVVN+R KGD+++VWTTD  + + I  IG+  K+ LG  +   I Y +H D   KS S  K  F +
Sbjct:   47 HPLQNRWSLWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDERNKKGGRWLITLNKQQRKLDLDRFWLETLLCLIGEAFDDYSDDVCGAVVNVRTKGDKIAVWTTDYENRDGITHIGRVYKERLGIPMKMTIGYQSHADTATKSGSTTKNKFVV 227

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BLAST of eIF4E1-like protein vs. Ensembl Cavefish
Match: eif4e1b (eukaryotic translation initiation factor 4E family member 1B [Source:NCBI gene;Acc:30738])

HSP 1 Score: 143.28 bits (360), Expect = 9.958e-42
Identity = 78/181 (43.09%), Postives = 107/181 (59.12%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +F+KND+SK W DN++ +  FDT EDFW L N+I   SKL SGCDY VFK  + P     R      +LL             C L+ L+ ++GE F   S ++CG+V+N+R KGD+++VWTT+  +AEA+  IG+K K+ LGL     I Y AH D   KS+S  K  F +
Sbjct:   35 HPLQNRWALWFYKNDKSKMWQDNLRLITKFDTAEDFWALYNNIQAASKLSSGCDYSVFK--VNP-----RVYKACFFLL-------------CILQ-LLCMIGEGFGSYSRDVCGSVINVRAKGDKIAVWTTNTENAEAVTHIGRKYKEILGLPSKLVIGYQAHADTATKSNSITKNKFVV 194

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BLAST of eIF4E1-like protein vs. Ensembl Cavefish
Match: eif4e2 (eukaryotic translation initiation factor 4E family member 2 [Source:NCBI gene;Acc:103021705])

HSP 1 Score: 110.153 bits (274), Expect = 1.219e-28
Identity = 57/172 (33.14%), Postives = 93/172 (54.07%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKND-----RSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDA 614
            H LQ  +TF++ +        ++ +  N+K++  F +VE FW   +H+  P  L    D+++FK+ I+PMWEDD NK+GG W++   K         CW  +++ ++GE F    +EICGAVV++R + D +S+W    S      RI   ++  L L     +EY  HTD+
Sbjct:   53 HPLQYNYTFWYSRRTPGRPASTQSYEQNIKQIGSFASVEQFWRFYSHMIRPGDLTGHSDFHLFKEGIKPMWEDDANKSGGKWIIRLRKGL----ASRCWENLILAMLGEQFM-VGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDS 219

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BLAST of eIF4E1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001509.1 (pep scaffold:Pmarinus_7.0:GL501028:982:8648:-1 gene:ENSPMAG00000001359.1 transcript:ENSPMAT00000001509.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 184.111 bits (466), Expect = 2.942e-58
Identity = 81/144 (56.25%), Postives = 105/144 (72.92%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIG 551
            H LQN+W  +F+KND+SK W  N++ +   DTVEDFW L NHI   S+L  GCDY +FKD I+PMWED+RNK GG WL+T  K QR S LD  WLE L+ L+GE F+D SD++CGAVVN+R K D+++VWT DC + E++  IG
Sbjct:   56 HPLQNRWALWFYKNDKSKSWQANLRLITKVDTVEDFWALYNHIQVASRLMPGCDYSLFKDGIEPMWEDERNKRGGRWLITLTKTQRHSDLDRYWLETLLCLIGEAFDDHSDDVCGAVVNVRPKADKIAVWTADCDNRESVVGIG 199

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BLAST of eIF4E1-like protein vs. Ensembl Sea Lamprey
Match: eif4e2 (eukaryotic translation initiation factor 4E family member 2 [Source:ZFIN;Acc:ZDB-GENE-050327-59])

HSP 1 Score: 107.842 bits (268), Expect = 1.419e-28
Identity = 58/172 (33.72%), Postives = 92/172 (53.49%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSK-----DWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDA 614
            H LQ  ++ +F +    +     ++  N+K +  F +VE FW   +HI  PS L    D+++FK+ I+PMWEDD NK+GG W++   K         CW  +++ ++GE F    +EICGAVV++R + D +S+W    S      RI   ++  L L     +EY  HTD+
Sbjct:   45 HPLQYNYSLWFSRRTPGRQASKQNYEQNIKHIGTFASVEMFWRFYSHIVRPSDLTGHSDFHLFKEGIKPMWEDDANKSGGKWIVRLRKGL----ASRCWENLILAMLGEQFM-VGEEICGAVVSLRFQEDIISIWNKTASDQGTTSRIRDTLRRVLNLPPNTIMEYKTHTDS 211

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BLAST of eIF4E1-like protein vs. Ensembl Yeast
Match: CDC33 (mRNA cap binding protein and translation initiation factor eIF4E; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with translation initiation factor eIF4G (Tif4631p or Tif4632p); protein abundance increases in response to DNA replication stress; mutants are defective for adhesion and pseudohyphal growth; human homolog EIF4E can complement yeast cdc33 null mutant [Source:SGD;Acc:S000005499])

HSP 1 Score: 124.79 bits (312), Expect = 2.342e-35
Identity = 62/172 (36.05%), Postives = 101/172 (58.72%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKN--DRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLT--CAIEYTAHTDAQNK 623
            H L  KWT ++ K   D+S+ W D ++ V  F TVE+FW ++ +I  P +LP   DY+VF++ ++P WED+ N  GG W  +F+   + + +D  WL  L+ ++GET ++D  +I G V++IR  G++ ++WT      E + RIG K K  L LT    +E+  H+ A  +
Sbjct:   37 HPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRNDVRPEWEDEANAKGGKW--SFQLRGKGADIDELWLRTLLAVIGETIDEDDSQINGVVLSIRKGGNKFALWTK-SEDKEPLLRIGGKFKQVLKLTDDGHLEFFPHSSANGR 205

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BLAST of eIF4E1-like protein vs. Ensembl Nematostella
Match: EDO49832 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7REQ6])

HSP 1 Score: 204.527 bits (519), Expect = 2.779e-66
Identity = 95/181 (52.49%), Postives = 121/181 (66.85%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCA--IEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  +FFKND+SK W  N++ +  FDTVEDFWG+ NHI   S+L  GCDY +FKD I+PMWED RNK+GG WL+   KNQR S LD  WLE L+ L+GE F + S+ +CGAVV IR KGD+++VWT + +  E  +RIGQ  K+ LGL     I Y AH D   K+ S  K  F +
Sbjct:    3 HPLQNRWVLWFFKNDKSKSWAANLRNITSFDTVEDFWGIYNHIQQASRLQPGCDYSLFKDGIEPMWEDKRNKDGGRWLINTNKNQRQSDLDRFWLETLLCLIGEAFGEYSEGVCGAVVQIRNKGDKIAVWTGNATDEEGTRRIGQVFKERLGLPPKMFIGYQAHQDTMTKTGSTTKSLFSV 183

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Nematostella
Match: EDO26680 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TBC7])

HSP 1 Score: 117.857 bits (294), Expect = 2.045e-33
Identity = 58/117 (49.57%), Postives = 74/117 (63.25%), Query Frame = 3

Query:  312 MWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCA--IEYTAHTDAQNKSSSRAKCTFRI 656
            MWED RNK+GG WL+   KNQR S LD  WLE L+ L+GE F + S+ +CGAVV IR KGD+++VWT + +  E  +RIGQ  K+ LGL     I Y AH D   K+ S  K  F +
Sbjct:    1 MWEDKRNKDGGRWLINTNKNQRQSDLDRFWLETLLCLIGEAFGEYSEGVCGAVVQIRNKGDKIAVWTGNATDEEGTRRIGQVFKERLGLPPKMFIGYQAHQDTMTKTGSTTKSLFSV 117

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Nematostella
Match: EDO43460 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYG8])

HSP 1 Score: 109.383 bits (272), Expect = 1.440e-28
Identity = 61/178 (34.27%), Postives = 95/178 (53.37%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSK-----DWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSS 632
            H LQ  + F+F +    K     ++ DN+K V  F +VE FWG  + +  P +L    D ++FKD I+PMWED+ NK GG W++   K         CW  +++ ++GE F   S E+CGAV+++R + D +S+W  + +      RI   +K  L L     +EY AH D+   +SS
Sbjct:   68 HPLQCPYVFWFSRRPPGKIQSATNYADNIKIVGKFASVEQFWGFYSFMVRPGELTGHSDIHLFKDGIKPMWEDEANKCGGKWIVRLRK----GLASRCWENLVLAMLGEQFMVGS-EVCGAVISVRFQEDIISIWNRNAADQATTTRIRDTLKRVLNLPPNTIMEYKAHQDSIKDNSS 240

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Nematostella
Match: EDO39481 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SA12])

HSP 1 Score: 73.559 bits (179), Expect = 1.646e-16
Identity = 34/107 (31.78%), Postives = 58/107 (54.21%), Query Frame = 3

Query:  126 LQNKWTFY---FFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETF 437
            L + WT +   + +   + ++  N++K+ +F TV+ FW + N+I   S+L S   Y+  + V +P+WED  N NGG W +   K+      D  W E+L+  +GE F
Sbjct:   19 LNSSWTLWHDRYIRGATAAEYAANLRKIYNFHTVQSFWSVFNNIPKASELGSRASYHCMRGVRRPIWEDAENANGGYWKMRCPKDM----TDKVWKELLLAAIGEQF 121

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Medaka
Match: eif4ea (eukaryotic translation initiation factor 4E-1A [Source:NCBI gene;Acc:100049330])

HSP 1 Score: 212.616 bits (540), Expect = 6.787e-68
Identity = 99/179 (55.31%), Postives = 126/179 (70.39%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAKCTF 650
            H LQN+WT +FFKND+SK W  N++ +  FDTVEDFW L NHI   S L SGCDY +FKD I+PMWED+RN+ GG WL+T  K QR   LD  WLE L+ LVGE F+D SD++CGAV+NIR KGD++++WTT+C + EAI +IG+  K+ LG+     I Y +H D   KSSS  K  F
Sbjct:   85 HPLQNRWTLWFFKNDKSKTWQANLRLISTFDTVEDFWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDERNRRGGRWLITLSKQQRKMDLDRFWLETLLCLVGEAFDDHSDDVCGAVINIRAKGDKIAIWTTNCENKEAITQIGRVYKERLGVPPKVIIGYQSHADTATKSSSTTKNKF 263

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Medaka
Match: eif4eb (eukaryotic translation initiation factor 4E [Source:NCBI gene;Acc:101166761])

HSP 1 Score: 203.371 bits (516), Expect = 5.428e-65
Identity = 96/181 (53.04%), Postives = 124/181 (68.51%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W+ +F+KND+SK W  N++ +  FDTVEDFW L NHI   S L SGCDY +FKD I+PMWED+RNK GG WL+T  K  R S LD  WLE L+ LVGE F+D SD++CGAVVN+R KGD+++VWT++  + EA+  IG+  K+ LGL     I Y +H D   KS S  K  F +
Sbjct:   36 HPLQNRWSLWFYKNDKSKTWQANLRLISKFDTVEDFWALYNHIQVSSNLISGCDYSLFKDGIEPMWEDERNKRGGRWLITLNKQLRRSDLDRFWLETLLCLVGEAFDDYSDDVCGAVVNVRNKGDKIAVWTSNYENREAVTHIGRVYKERLGLPMNMTIGYQSHADTATKSGSTTKNKFVV 216

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Medaka
Match: eif4e1c (eukaryotic translation initiation factor 4E [Source:NCBI gene;Acc:101169085])

HSP 1 Score: 202.601 bits (514), Expect = 1.142e-64
Identity = 95/181 (52.49%), Postives = 127/181 (70.17%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  ++FKND++K W +N++ +  FDTVEDFW L NHI  PSKL  GCDY +FKD I+PMWEDD+NK GG WL+T  K Q+ + LD  W+E L+ LVGE+F+D S+E+CGAVVN+R KGD++S+WT +C + EAI  IGQ  K+ L L     I Y +H D  +KS S  K  + +
Sbjct:   31 HPLQNRWALWYFKNDKTKSWTENLRLISKFDTVEDFWALYNHIQQPSKLVLGCDYCLFKDGIKPMWEDDKNKLGGRWLMTLNK-QKHNDLDRYWMETLLCLVGESFDDASEEVCGAVVNVRHKGDKISIWTGNCQNKEAIMTIGQLYKERLNLPMKAIIGYQSHDDTSSKSGSTTKNMYSV 210

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Medaka
Match: eif4e1c (eukaryotic translation initiation factor 4E [Source:NCBI gene;Acc:101169085])

HSP 1 Score: 202.216 bits (513), Expect = 1.998e-64
Identity = 95/181 (52.49%), Postives = 127/181 (70.17%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W  ++FKND++K W +N++ +  FDTVEDFW L NHI  PSKL  GCDY +FKD I+PMWEDD+NK GG WL+T  K Q+ + LD  W+E L+ LVGE+F+D S+E+CGAVVN+R KGD++S+WT +C + EAI  IGQ  K+ L L     I Y +H D  +KS S  K  + +
Sbjct:   37 HPLQNRWALWYFKNDKTKSWTENLRLISKFDTVEDFWALYNHIQQPSKLVLGCDYCLFKDGIKPMWEDDKNKLGGRWLMTLNK-QKHNDLDRYWMETLLCLVGESFDDASEEVCGAVVNVRHKGDKISIWTGNCQNKEAIMTIGQLYKERLNLPMKAIIGYQSHDDTSSKSGSTTKNMYSV 216

[Close]

BLAST of eIF4E1-like protein vs. Ensembl Medaka
Match: eif4eb (eukaryotic translation initiation factor 4E [Source:NCBI gene;Acc:101166761])

HSP 1 Score: 202.986 bits (515), Expect = 2.347e-64
Identity = 96/181 (53.04%), Postives = 124/181 (68.51%), Query Frame = 3

Query:  120 HYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGL--TCAIEYTAHTDAQNKSSSRAKCTFRI 656
            H LQN+W+ +F+KND+SK W  N++ +  FDTVEDFW L NHI   S L SGCDY +FKD I+PMWED+RNK GG WL+T  K  R S LD  WLE L+ LVGE F+D SD++CGAVVN+R KGD+++VWT++  + EA+  IG+  K+ LGL     I Y +H D   KS S  K  F +
Sbjct:   63 HPLQNRWSLWFYKNDKSKTWQANLRLISKFDTVEDFWALYNHIQVSSNLISGCDYSLFKDGIEPMWEDERNKRGGRWLITLNKQLRRSDLDRFWLETLLCLVGEAFDDYSDDVCGAVVNVRNKGDKIAVWTSNYENREAVTHIGRVYKERLGLPMNMTIGYQSHADTATKSGSTTKNKFVV 243

[Close]

BLAST of eIF4E1-like protein vs. Planmine SMEST
Match: SMESG000031703.1 (SMESG000031703.1)

HSP 1 Score: 399.438 bits (1025), Expect = 2.143e-142
Identity = 212/212 (100.00%), Postives = 212/212 (100.00%), Query Frame = 3

Query:   21 MVDETSLGXXXXXXXXXXXXXXXXXXXAGDSELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDAQNKSSSRAKCTFRI 656
            MVDETSLGNLSNLKLEDEDNEENLKSLAGDSELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDAQNKSSSRAKCTFRI
Sbjct:    1 MVDETSLGNLSNLKLEDEDNEENLKSLAGDSELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDAQNKSSSRAKCTFRI 212

[Close]

BLAST of eIF4E1-like protein vs. Planmine SMEST
Match: SMESG000062612.1 (SMESG000062612.1)

HSP 1 Score: 205.682 bits (522), Expect = 3.062e-66
Identity = 87/177 (49.15%), Postives = 127/177 (71.75%), Query Frame = 3

Query:  126 LQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDAQNKSSSRAKCTFRI 656
            L ++W FY+FK D+ K WI+NM K++  D++E FWG+M+H+ P S L  G D+Y F+  I+PMWED  N+NGG W+++  K++R + LD  W+E+LM L+GET ++DSD ICGA +NIRG  D+++VWT+D S+ EA +RIG K+K  L L   IEY +H + QNK++S AK T  +
Sbjct:   18 LADQWNFYYFKLDKKKQWIENMNKILTIDSIESFWGIMHHLKPISTLNFGSDFYFFRSHIRPMWEDTSNQNGGTWIISSHKSKRHTELDILWMELLMFLIGETMDEDSDLICGAAINIRGTNDKITVWTSDSSNLEANRRIGMKLKSILNLHDTIEYISHINNQNKNNSSAKVTLTV 194

[Close]

BLAST of eIF4E1-like protein vs. Planmine SMEST
Match: SMESG000046515.1 (SMESG000046515.1)

HSP 1 Score: 191.045 bits (484), Expect = 1.439e-60
Identity = 82/180 (45.56%), Postives = 122/180 (67.78%), Query Frame = 3

Query:  117 LHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDAQNKSSSRAKCTFRI 656
            ++ L ++W  Y+FK D+ K WIDNMK +   D+VE FWG++ H+ P S +  GCDYY F+  I PMWE++ N+NGG W+++  K++R S L+  W E+LM L+GET  +DS EICGA +NIRG  D+++VWT + ++ E  KRIG ++K  L LT  IEY +H++ Q K++   K T  +
Sbjct:   11 INKLADEWKIYYFKMDKEKRWIDNMKTIFTVDSVESFWGILRHLKPVSDMSYGCDYYFFRKHIAPMWENEFNQNGGTWVISSHKSKRHSELNSMWTEVLMFLIGETTNEDSSEICGAAINIRGNYDKITVWTANSANDETNKRIGLQLKSLLNLTTTIEYISHSENQKKNNCAPKPTLIV 190

[Close]

BLAST of eIF4E1-like protein vs. Planmine SMEST
Match: SMESG000074929.1 (SMESG000074929.1)

HSP 1 Score: 162.155 bits (409), Expect = 1.341e-48
Identity = 73/169 (43.20%), Postives = 109/169 (64.50%), Query Frame = 3

Query:  108 DSELHYLQNKWTFYFFKNDRSKDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDA 614
            ++  +YLQN+W+ +F K D S+DW +++  +  F+TVEDFW L++HI PP  LP+GCDYY+F+  I+PMWE + N+ GG W +TF+ + R   L+  W  + MLLVGE    DS+ +CG VVN+R   DR+ +W ++    + I RIG+ IK  L +   IE+  H D 
Sbjct:   59 ETAFNYLQNEWSLWFCKRDSSRDWTESLHLIEHFNTVEDFWRLIDHITPPFALPTGCDYYLFRRDIKPMWEHNTNRCGGSWQVTFKNSTRSLLLNRFWENLTMLLVGEGCGSDSEIVCGGVVNVRKMTDRLCLWVSNYEDKQQIMRIGRHIKRILEIDFPIEFYPHIDV 227

[Close]

BLAST of eIF4E1-like protein vs. Planmine SMEST
Match: SMESG000046520.1 (SMESG000046520.1)

HSP 1 Score: 149.828 bits (377), Expect = 3.122e-45
Identity = 63/137 (45.99%), Postives = 94/137 (68.61%), Query Frame = 3

Query:  189 MKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWEDDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAVVNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYT 599
            MK +   D+VE FWG+++H+ P S +  GCDYY F+  I PMWE++ N+NGG W+++  K++R S L+  W E+LM L+GET  +DS EICGA +NIRG  D+++VWT + ++ E  KRIG ++K  L LT    ++
Sbjct:    1 MKPMFTVDSVESFWGILSHLKPVSDMSYGCDYYFFRKHIAPMWENEFNQNGGTWVISSHKSKRHSELNSMWTEVLMFLIGETTNEDSSEICGAAINIRGNYDKITVWTANSANDETNKRIGLQLKSLLNLTTTTYFS 137

The following BLAST results are available for this feature:

BLAST of eIF4E1-like protein vs. Ensembl Human
BLAST of eIF4E1-like protein vs. Ensembl Celegans
BLAST of eIF4E1-like protein vs. Ensembl Fly
BLAST of eIF4E1-like protein vs. Ensembl Zebrafish
BLAST of eIF4E1-like protein vs. Ensembl Xenopus
BLAST of eIF4E1-like protein vs. Ensembl Mouse
BLAST of eIF4E1-like protein vs. UniProt/SwissProt
BLAST of eIF4E1-like protein vs. TrEMBL
BLAST of eIF4E1-like protein vs. Ensembl Cavefish
BLAST of eIF4E1-like protein vs. Ensembl Sea Lamprey
BLAST of eIF4E1-like protein vs. Ensembl Yeast
BLAST of eIF4E1-like protein vs. Ensembl Nematostella
BLAST of eIF4E1-like protein vs. Ensembl Medaka
BLAST of eIF4E1-like protein vs. Planmine SMEST

BLAST of eIF4E1-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
EIF4E1B	8.031e-67	54.10	eukaryotic translation initiation factor 4E family...	[more]
EIF4E1B	8.031e-67	54.10	eukaryotic translation initiation factor 4E family...	[more]
EIF4E1B	8.031e-67	54.10	eukaryotic translation initiation factor 4E family...	[more]
EIF4E	2.548e-66	53.04	eukaryotic translation initiation factor 4E [Sourc...	[more]
EIF4E	3.693e-66	53.04	eukaryotic translation initiation factor 4E [Sourc...	[more]

BLAST of eIF4E1-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ife-3	2.082e-53	48.86	Eukaryotic translation initiation factor 4E-3 [So...	[more]
ife-3	2.082e-53	48.86	Eukaryotic translation initiation factor 4E-3 [So...	[more]
ife-3	1.831e-51	48.31	Eukaryotic translation initiation factor 4E-3 [So...	[more]
ife-3	1.831e-51	48.31	Eukaryotic translation initiation factor 4E-3 [So...	[more]
ife-3	2.415e-51	48.04	Eukaryotic translation initiation factor 4E-3 [So...	[more]

BLAST of eIF4E1-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eIF4E1	9.876e-57	47.51	gene:FBgn0015218 transcript:FBtr0076488	[more]
eIF4E1	1.642e-56	47.51	gene:FBgn0015218 transcript:FBtr0076493	[more]
eIF4E1	1.642e-56	47.51	gene:FBgn0015218 transcript:FBtr0076489	[more]
eIF4E1	1.642e-56	47.51	gene:FBgn0015218 transcript:FBtr0076490	[more]
eIF4E1	1.642e-56	47.51	gene:FBgn0015218 transcript:FBtr0076487	[more]

BLAST of eIF4E1-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eif4e1c	6.603e-66	51.38	eukaryotic translation initiation factor 4E family...	[more]
eif4e1c	8.527e-66	51.38	eukaryotic translation initiation factor 4E family...	[more]
eif4e1c	8.527e-66	51.38	eukaryotic translation initiation factor 4E family...	[more]
eif4ea	1.185e-65	54.14	eukaryotic translation initiation factor 4ea [Sour...	[more]
eif4ea	1.279e-65	54.14	eukaryotic translation initiation factor 4ea [Sour...	[more]

BLAST of eIF4E1-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSXETT00000049404.1	9.077e-65	51.93	eukaryotic translation initiation factor 4E family...	[more]
snx1	1.024e-64	51.93	sorting nexin 1 [Source:Xenbase;Acc:XB-GENE-992259...	[more]
ENSXETT00000049401.1	2.120e-64	51.93	eukaryotic translation initiation factor 4E family...	[more]
snx1	6.522e-64	51.93	sorting nexin 1 [Source:Xenbase;Acc:XB-GENE-992259...	[more]
txnrd1	3.009e-30	34.30	thioredoxin reductase 1 [Source:Xenbase;Acc:XB-GEN...	[more]

BLAST of eIF4E1-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Eif4e	7.919e-66	52.49	eukaryotic translation initiation factor 4E [Sourc...	[more]
Eif4e1b	2.060e-59	51.12	eukaryotic translation initiation factor 4E family...	[more]
Eif4e1b	2.060e-59	51.12	eukaryotic translation initiation factor 4E family...	[more]
Eif4e1b	2.191e-59	51.12	eukaryotic translation initiation factor 4E family...	[more]
Eif4e	3.825e-59	56.55	eukaryotic translation initiation factor 4E [Sourc...	[more]

BLAST of eIF4E1-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O77210\|IF4E_APLCA	3.869e-67	54.14	Eukaryotic translation initiation factor 4E OS=Apl...	[more]
sp\|A6NMX2\|I4E1B_HUMAN	3.857e-66	54.10	Eukaryotic translation initiation factor 4E type 1...	[more]
sp\|P06730\|IF4E_HUMAN	1.224e-65	53.04	Eukaryotic translation initiation factor 4E OS=Hom...	[more]
sp\|Q9N0T5\|IF4E_BOVIN	3.587e-65	52.49	Eukaryotic translation initiation factor 4E OS=Bos...	[more]
sp\|P63074\|IF4E_RAT	5.539e-65	52.49	Eukaryotic translation initiation factor 4E OS=Rat...	[more]

BLAST of eIF4E1-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
D2DJT8	5.322e-111	100.00	eIF4E1-like protein (Fragment) OS=Schmidtea medite...	[more]
D5JG41	8.445e-103	75.48	Eukaryotic initiation factor-4E (Fragment) OS=Duge...	[more]
A0A1W6I191	1.155e-93	98.11	Translation initiation factor 4E-like protein (Fra...	[more]
K1PGU1	1.080e-67	54.14	Eukaryotic translation initiation factor 4E OS=Cra...	[more]
A0A210PSB7	1.664e-67	56.35	Eukaryotic translation initiation factor 4E OS=Miz...	[more]

BLAST of eIF4E1-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eif4ea	1.943e-65	54.70	eukaryotic translation initiation factor 4E-1A [So...	[more]
eif4e1c	1.100e-64	50.83	eukaryotic translation initiation factor 4E-like [...	[more]
eif4eb	3.809e-64	53.04	eukaryotic translation initiation factor 4E-1A [So...	[more]
eif4e1b	9.958e-42	43.09	eukaryotic translation initiation factor 4E family...	[more]
eif4e2	1.219e-28	33.14	eukaryotic translation initiation factor 4E family...	[more]

BLAST of eIF4E1-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000001509.1	2.942e-58	56.25	pep scaffold:Pmarinus_7.0:GL501028:982:8648:-1 gen...	[more]
eif4e2	1.419e-28	33.72	eukaryotic translation initiation factor 4E family...	[more]

BLAST of eIF4E1-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
CDC33	2.342e-35	36.05	mRNA cap binding protein and translation initiatio...	[more]

BLAST of eIF4E1-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4


Match Name	E-value	Identity	Description
EDO49832	2.779e-66	52.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26680	2.045e-33	49.57	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43460	1.440e-28	34.27	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39481	1.646e-16	31.78	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of eIF4E1-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
eif4ea	6.787e-68	55.31	eukaryotic translation initiation factor 4E-1A [So...	[more]
eif4eb	5.428e-65	53.04	eukaryotic translation initiation factor 4E [Sourc...	[more]
eif4e1c	1.142e-64	52.49	eukaryotic translation initiation factor 4E [Sourc...	[more]
eif4e1c	1.998e-64	52.49	eukaryotic translation initiation factor 4E [Sourc...	[more]
eif4eb	2.347e-64	53.04	eukaryotic translation initiation factor 4E [Sourc...	[more]

BLAST of eIF4E1-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000031703.1	2.143e-142	100.00	SMESG000031703.1	[more]
SMESG000062612.1	3.062e-66	49.15	SMESG000062612.1	[more]
SMESG000046515.1	1.439e-60	45.56	SMESG000046515.1	[more]
SMESG000074929.1	1.341e-48	43.20	SMESG000074929.1	[more]
SMESG000046520.1	3.122e-45	45.99	SMESG000046520.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30021622
GenBank	ACT98275.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30021622 ID=SMED30021622|Name=eIF4E1-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=858bp
CTATATAAATCTTATATGAAATGGTTGATGAAACATCGTTGGGGAATTTA
TCAAATTTAAAATTAGAAGACGAAGATAATGAGGAAAATTTGAAAAGCTT
AGCAGGTGATTCAGAATTACATTATCTGCAAAATAAGTGGACGTTTTACT
TTTTTAAAAATGATAGAAGTAAGGATTGGATTGATAATATGAAGAAAGTT
ATTGATTTTGACACCGTCGAAGATTTTTGGGGTTTAATGAATCATATAGC
TCCTCCTTCTAAATTGCCATCTGGATGTGATTATTATGTATTTAAAGATG
TAATTCAGCCTATGTGGGAAGACGACAGAAATAAGAATGGAGGTATGTGG
CTGTTAACATTTGAAAAAAATCAGCGCATTTCCCACCTTGATCCTTGTTG
GTTGGAAATTCTTATGCTTTTAGTTGGTGAAACTTTTGAAGATGATTCAG
ATGAAATATGCGGTGCAGTCGTCAATATAAGAGGTAAAGGTGATCGTGTT
AGTGTATGGACCACAGATTGTTCATCTGCAGAAGCTATTAAGCGAATTGG
ACAAAAAATTAAAGACGCTCTTGGTTTAACATGTGCTATAGAATACACAG
CTCATACTGATGCACAGAATAAATCAAGTTCAAGAGCAAAGTGCACTTTT
AGAATATAATTATCAAGTGTGATTAGGTGTAATTTTTGTGTTTCTGTGGT
TAAAATTTCCCTTTATATGAACTGTTGCTTAAATATGAATCCCTGTTTAT
TTTGTTAATAGTTAGTGATTGTTCAGTTTTTAGATTATTTAAATTTAATT
AAAAAGTCAAATCGATATTATCTACTTTGTTAAAAATTAATTCATTTGGT
ATTGGGCG

protein sequence of SMED30021622-orf-1

>SMED30021622-orf-1 ID=SMED30021622-orf-1|Name=SMED30021622-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=213bp
MVDETSLGNLSNLKLEDEDNEENLKSLAGDSELHYLQNKWTFYFFKNDRS
KDWIDNMKKVIDFDTVEDFWGLMNHIAPPSKLPSGCDYYVFKDVIQPMWE
DDRNKNGGMWLLTFEKNQRISHLDPCWLEILMLLVGETFEDDSDEICGAV
VNIRGKGDRVSVWTTDCSSAEAIKRIGQKIKDALGLTCAIEYTAHTDAQN
KSSSRAKCTFRI*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000074	oocyte
PLANA:0000204	ovary
PLANA:0000208	testis
PLANA:0000231	vitelline gland
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR001040	TIF_eIF_4E
IPR023398	TIF_eIF4e-like

Vocabulary: **molecular function**
Term	Definition
GO:0003743	translation initiation factor activity
GO:0003723	RNA binding

Vocabulary: **biological process**
Term	Definition
GO:0006413	translational initiation
GO:0006412	translation
GO:0006417	regulation of translation

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR023398	Translation Initiation factor eIF- 4e-like	GENE3D	G3DSA:3.30.760.10		coord: 29..213 e-value: 4.4E-71 score: 240.3
IPR023398	Translation Initiation factor eIF- 4e-like	SUPERFAMILY	SSF55418	eIF4e-like	coord: 11..208
IPR001040	Translation Initiation factor eIF- 4e	PFAM	PF01652	IF4E	coord: 37..188 e-value: 7.9E-55 score: 185.0
IPR001040	Translation Initiation factor eIF- 4e	PANTHER	PTHR11960	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED	coord: 24..211
None	No IPR available	PANTHER	PTHR11960:SF3	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 1B	coord: 24..211