slc12a-5

Overview


Name	slc12a-5 (AKN21479.1)
Smed ID	SMED30021618
Length (bp)	2368

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of slc12a-5 (SMED30021618) t-SNE clustered cells

Violin plots show distribution of expression levels for slc12a-5 (SMED30021618) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of slc12a-5 (SMED30021618) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for slc12a-5 (SMED30021618) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30021618

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
gut	SMED30021618	h1SMcG0020739	dd_Smed_v4_8108_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30021618	h1SMcG0020739	dd_Smed_v4_8108_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of slc12a-5 vs. Ensembl Human
Match: SLC12A8 (solute carrier family 12 member 8 [Source:HGNC Symbol;Acc:HGNC:15595])

HSP 1 Score: 313.538 bits (802), Expect = 4.147e-95
Identity = 217/493 (44.02%), Postives = 312/493 (63.29%), Query Frame = 1

Query:  313 NRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAK-SFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHST--GSNLE-NSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIK 1779
             +D   + +PWWKT   + E V FGTWDGVFTSCMINIFGVV+FLRTGW+VG  G+ L + ++   +++AL+ +LS IG+ ER  I SGGVY ++S VLG +   ++G LY FGQ VA ++Y +GF ESIS LLG  N W  +GI V +L+ LLG+NL GVKW+IRLQLLLL +L ++ LDF+VGSF    P  G +GYS E  +NNT   ++   +FF+VFGVFFP ATGV AG NM GDLR P  SIPLG+L+A+G+S+ LY+ F   LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  A LG+  G NK PV ++ +   +T++F+F+G +N+L PIVT  F++TY  + Y+YF L+  S  +    E + +     + ++G+  S  + ++      S+G       G+ LE    +D+      +L+   P +     T E+    S  K  K+ ++
Sbjct:   16 QQDALAQPQPWWKTQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERSSIGSGGVYSMISSVLGGQTGGTIGLLYVFGQCVAGAMYITGFAESISDLLGLGNIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLFLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQNNTLPDYSPGESFFTVFGVFFPAATGVMAGFNMGGDLREPAASIPLGSLAAVGISWFLYIIFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLYGAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTINFMLTYVAVDYSYFSLSMCSCSLTPVPEPVLR-----EGAEGLHCSEHLLLEKAPSYGSEGPAQRVLEGTLLEFTKDMDQLLQLTRKLESSQPRQGEGNRTPESQKRKS-KKATKQTLQ 502

HSP 2 Score: 80.1073 bits (196), Expect = 8.097e-15
Identity = 46/163 (28.22%), Postives = 94/163 (57.67%), Query Frame = 1

Query: 1687 DRLFPERISYGATAETNSDNSFPK---INKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCI-SHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVI 2160
            ++L PE  +    +E++ ++ F K     +++ ++  SFY+   N W+SL G    +L+MF ++W Y+L+ +G+  ++Y YIG  +PGL  G A  FS    + S L  + RS  S QE +++++  + ++  E   +T E+ D+  R +YH +  +++++++
Sbjct:  553 EQLVPELCN---QSESSGEDFFLKSRLQEQDVWRRSTSFYTHMCNPWVSLLGAVGSLLIMFVIQWVYTLVNMGVAAIVYFYIGRASPGLHLGSASNFSFFRWMRSLLLPSCRSLRSPQE-QIILAPSLAKVDMEMTQLTQENADFATRDRYHHSSLVNREQLM 711

[Close]

Query:  313 NRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAK-SFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHST--GSNLE-NSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIK 1779
             +D   + +PWWKT   + E V FGTWDGVFTSCMINIFGVV+FLRTGW+VG  G+ L + ++   +++AL+ +LS IG+ ER  I SGGVY ++S VLG +   ++G LY FGQ VA ++Y +GF ESIS LLG  N W  +GI V +L+ LLG+NL GVKW+IRLQLLLL +L ++ LDF+VGSF    P  G +GYS E  +NNT   ++   +FF+VFGVFFP ATGV AG NM GDLR P  SIPLG+L+A+G+S+ LY+ F   LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  A LG+  G NK PV ++ +   +T++F+F+G +N+L PIVT  F++TY  + Y+YF L+  S  +    E + +     + ++G+  S  + ++      S+G       G+ LE    +D+      +L+   P +     T E+    S  K  K+ ++
Sbjct:   16 QQDALAQPQPWWKTQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERSSIGSGGVYSMISSVLGGQTGGTIGLLYVFGQCVAGAMYITGFAESISDLLGLGNIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLFLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQNNTLPDYSPGESFFTVFGVFFPAATGVMAGFNMGGDLREPAASIPLGSLAAVGISWFLYIIFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLYGAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTINFMLTYVAVDYSYFSLSMCSCSLTPVPEPVLR-----EGAEGLHCSEHLLLEKAPSYGSEGPAQRVLEGTLLEFTKDMDQLLQLTRKLESSQPRQGEGNRTPESQKRKS-KKATKQTLQ 502

HSP 2 Score: 80.1073 bits (196), Expect = 8.097e-15
Identity = 46/163 (28.22%), Postives = 94/163 (57.67%), Query Frame = 1

Query: 1687 DRLFPERISYGATAETNSDNSFPK---INKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCI-SHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVI 2160
            ++L PE  +    +E++ ++ F K     +++ ++  SFY+   N W+SL G    +L+MF ++W Y+L+ +G+  ++Y YIG  +PGL  G A  FS    + S L  + RS  S QE +++++  + ++  E   +T E+ D+  R +YH +  +++++++
Sbjct:  553 EQLVPELCN---QSESSGEDFFLKSRLQEQDVWRRSTSFYTHMCNPWVSLLGAVGSLLIMFVIQWVYTLVNMGVAAIVYFYIGRASPGLHLGSASNFSFFRWMRSLLLPSCRSLRSPQE-QIILAPSLAKVDMEMTQLTQENADFATRDRYHHSSLVNREQLM 711

[Close]

BLAST of slc12a-5 vs. Ensembl Human
Match: SLC12A2 (solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911])

HSP 1 Score: 154.066 bits (388), Expect = 9.889e-38
Identity = 136/420 (32.38%), Postives = 229/420 (54.52%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWI------AKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV---KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGG-------------------TCTPEI------------------LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF--VLAKS 1491
            V+FG   GV   CM+NI+GV++F+R  W+VG AG+GLSVL+I++  ++  I  LS   +     +  GG Y+L+S  LG     ++G ++ F  AVA ++Y  GF E++  LL   +  +       + IG   ++ILLG+++ G++W  + Q++LL+IL +A+ DF++G+F+    + P  G  GY  E F  N    F  E TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL AI ++ ++Y+  A+++G                     CT                     L  +  + + V+   PL+  G++ ++LS+AL  + +AP++ + + +    P      + +GKN  P+   ++   I + FI I  +N++ PI++  FL +YA ++++ F   LAKS
Sbjct:  283 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLESKKPK-GFFGYKSEIFNENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKS 701

[Close]

BLAST of slc12a-5 vs. Ensembl Human
Match: SLC12A2 (solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911])

HSP 1 Score: 153.68 bits (387), Expect = 1.144e-37
Identity = 136/420 (32.38%), Postives = 229/420 (54.52%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWI------AKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV---KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGG-------------------TCTPEI------------------LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF--VLAKS 1491
            V+FG   GV   CM+NI+GV++F+R  W+VG AG+GLSVL+I++  ++  I  LS   +     +  GG Y+L+S  LG     ++G ++ F  AVA ++Y  GF E++  LL   +  +       + IG   ++ILLG+++ G++W  + Q++LL+IL +A+ DF++G+F+    + P  G  GY  E F  N    F  E TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL AI ++ ++Y+  A+++G                     CT                     L  +  + + V+   PL+  G++ ++LS+AL  + +AP++ + + +    P      + +GKN  P+   ++   I + FI I  +N++ PI++  FL +YA ++++ F   LAKS
Sbjct:  283 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLESKKPK-GFFGYKSEIFNENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKS 701

[Close]

BLAST of slc12a-5 vs. Ensembl Human
Match: SLC12A2 (solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911])

HSP 1 Score: 153.68 bits (387), Expect = 1.382e-37
Identity = 136/420 (32.38%), Postives = 229/420 (54.52%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWI------AKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV---KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGG-------------------TCTPEI------------------LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF--VLAKS 1491
            V+FG   GV   CM+NI+GV++F+R  W+VG AG+GLSVL+I++  ++  I  LS   +     +  GG Y+L+S  LG     ++G ++ F  AVA ++Y  GF E++  LL   +  +       + IG   ++ILLG+++ G++W  + Q++LL+IL +A+ DF++G+F+    + P  G  GY  E F  N    F  E TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL AI ++ ++Y+  A+++G                     CT                     L  +  + + V+   PL+  G++ ++LS+AL  + +AP++ + + +    P      + +GKN  P+   ++   I + FI I  +N++ PI++  FL +YA ++++ F   LAKS
Sbjct:  283 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLESKKPK-GFFGYKSEIFNENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKS 701

[Close]

BLAST of slc12a-5 vs. Ensembl Celegans
Match: F10E7.9 (pep chromosome:WBcel235:II:7106412:7110056:-1 gene:WBGene00017350.1 transcript:F10E7.9.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F10E7.9)

HSP 1 Score: 309.686 bits (792), Expect = 3.156e-95
Identity = 223/626 (35.62%), Postives = 342/626 (54.63%), Query Frame = 1

Query:  325 ENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTH-------------ENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIV-TEPICVTDESL---DYIDRGKYHQAQKMDKD 2151
            ++ + PWW+   L  + V FGTWDGVF + M+NIFG+++FLR GW+VG AG+  S+L++ +   +ALI + SAIG+ ERC+I+SGG+YFL+SHVLG ++  ++G +Y FGQAVA+ L A GFGES++ L    +  + KGI +  L++L  VN  GV WV+RLQ++LLL + +AV DF+ G+     P  GV  +S E  R N  + +               E +FF+VFGVFF    GV AG+NMSGDL++P KSIPLG LSA+GVS  +   F + LGG      L  D MI+ KVA  G + L GLYV SLS+ +G +   PR+L+ IAE   +P    L R  G N  PV +  +++ +   F+ +G++N L  + T PFL+TYA ++Y+Y  LA S+D+          + H+ + + V                 G+  +   N              +L+ LFPER     T+   ++         II Q  ++YS+F NR++S  G  + + ++  + + +++        LY YIG V P   PG++ FS+      + S++ S  S        +  +PE   T  +  + ++    DY DR +YH ++ +   
Sbjct:   28 DSSQLPWWQRTILTKDKVLFGTWDGVFATVMVNIFGIIVFLRLGWIVGTAGVANSILLLGICTSLALITVFSAIGIVERCQIKSGGIYFLVSHVLGHQIGGAIGIIYAFGQAVATGLVAVGFGESVAHLFESESKIMIKGIAILTLMVLTAVNTAGVTWVVRLQIVLLLTIALAVTDFIFGALFSSEPESGVFRFSSERIRVNADSHYEAVNCSIIGIPRQIPEQSFFTVFGVFFANFLGVLAGVNMSGDLKDPHKSIPLGELSAVGVSSTICFIFIMILGGVGDRMFLLCDVMISEKVALTGIVFLVGLYVCSLSSTVGSLLGTPRVLQGIAEEGIIPCLNVLARGVGPNDNPVLAGYLLMGVASLFVLLGDLNQLAILSTMPFLITYAYVNYSYVSLAMSYDL--------ATVQHADEVETV-----------------GYGSTNKMN--------------DLNELFPERRDVNITSTEETETG-------IISQEATWYSMFSNRYVSFLGFLVNLAILLLIHFWFAVAHFVALIALYWYIGRVCPTCGPGISTFSLCHMFKTVFSSLDSLRSGA------TTILPETTFTSGVSSSQQNEANPDYQDRRQYHHSENVSHQ 601

[Close]

BLAST of slc12a-5 vs. Ensembl Celegans
Match: nkcc-1 (Na-K-Cl Cotransporter homolog [Source:UniProtKB/TrEMBL;Acc:L8E912])

HSP 1 Score: 187.193 bits (474), Expect = 5.686e-49
Identity = 135/403 (33.50%), Postives = 223/403 (55.33%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNP--------WIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGT----------------------CTPEI---LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            V+FG   GVF  C++NIFGV+++LR  W+ G AG+GL   I++L  ++  I  LS   +C    ++ GG YFL+S  LG     S+G ++    AV +++Y  GF ES   +L   N         W  + IG    +IL+G+   G ++  ++QL LL+IL +++ +++ GSF        + G  GYS++T ++N    FT  NTFFSVF V+FP ATG+ AG N+SGDL NP+++IPLGTL AI V+ ++Y+      G T                      CTP+    L     +    +F GPL+  G++ ++LS+AL  + +AP++ + + +    P   +  + +GKN+ P  + ++   + +  + IG++N++ PI++  FL +YA ++YA F
Sbjct:  242 VKFGWIQGVFVRCLLNIFGVMLYLRVSWVSGQAGVGLGSCIVLLASVVTTITALSTCAICTNGDVKGGGAYFLISRSLGPEFGGSIGIIFSIANAVGAAMYIVGFAESFRDVLIDYNIGTIFDGGLWDVRVIGFVTCVILMGIVFIGSEFESKMQLGLLVILLVSIANYVFGSFFPPNEIAMNRGATGYSLDTLQSNFMPHFTENNTFFSVFSVYFPAATGIMAGANISGDLANPQQAIPLGTLLAILVTTIVYLLTVWMTGSTVVAFSNGTEPAVFNNSYFVPPDCTPDCPFGLVSYYQVVEMSSFWGPLITAGIFAATLSSALASLVSAPKVFQAVCKDRLFPRIDYFAKTYGKNEEPKRAYVLGFFLAMGIVAIGDLNVIAPIISNFFLGSYALINYACF 644

[Close]

BLAST of slc12a-5 vs. Ensembl Celegans
Match: nkcc-1 (Na-K-Cl Cotransporter homolog [Source:UniProtKB/TrEMBL;Acc:L8E912])

HSP 1 Score: 187.193 bits (474), Expect = 8.524e-49
Identity = 135/403 (33.50%), Postives = 223/403 (55.33%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNP--------WIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGT----------------------CTPEI---LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            V+FG   GVF  C++NIFGV+++LR  W+ G AG+GL   I++L  ++  I  LS   +C    ++ GG YFL+S  LG     S+G ++    AV +++Y  GF ES   +L   N         W  + IG    +IL+G+   G ++  ++QL LL+IL +++ +++ GSF        + G  GYS++T ++N    FT  NTFFSVF V+FP ATG+ AG N+SGDL NP+++IPLGTL AI V+ ++Y+      G T                      CTP+    L     +    +F GPL+  G++ ++LS+AL  + +AP++ + + +    P   +  + +GKN+ P  + ++   + +  + IG++N++ PI++  FL +YA ++YA F
Sbjct:  220 VKFGWIQGVFVRCLLNIFGVMLYLRVSWVSGQAGVGLGSCIVLLASVVTTITALSTCAICTNGDVKGGGAYFLISRSLGPEFGGSIGIIFSIANAVGAAMYIVGFAESFRDVLIDYNIGTIFDGGLWDVRVIGFVTCVILMGIVFIGSEFESKMQLGLLVILLVSIANYVFGSFFPPNEIAMNRGATGYSLDTLQSNFMPHFTENNTFFSVFSVYFPAATGIMAGANISGDLANPQQAIPLGTLLAILVTTIVYLLTVWMTGSTVVAFSNGTEPAVFNNSYFVPPDCTPDCPFGLVSYYQVVEMSSFWGPLITAGIFAATLSSALASLVSAPKVFQAVCKDRLFPRIDYFAKTYGKNEEPKRAYVLGFFLAMGIVAIGDLNVIAPIISNFFLGSYALINYACF 622

[Close]

BLAST of slc12a-5 vs. Ensembl Celegans
Match: nkcc-1 (Na-K-Cl Cotransporter homolog [Source:UniProtKB/TrEMBL;Acc:L8E912])

HSP 1 Score: 186.808 bits (473), Expect = 1.000e-48
Identity = 135/403 (33.50%), Postives = 223/403 (55.33%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNP--------WIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGT----------------------CTPEI---LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            V+FG   GVF  C++NIFGV+++LR  W+ G AG+GL   I++L  ++  I  LS   +C    ++ GG YFL+S  LG     S+G ++    AV +++Y  GF ES   +L   N         W  + IG    +IL+G+   G ++  ++QL LL+IL +++ +++ GSF        + G  GYS++T ++N    FT  NTFFSVF V+FP ATG+ AG N+SGDL NP+++IPLGTL AI V+ ++Y+      G T                      CTP+    L     +    +F GPL+  G++ ++LS+AL  + +AP++ + + +    P   +  + +GKN+ P  + ++   + +  + IG++N++ PI++  FL +YA ++YA F
Sbjct:  218 VKFGWIQGVFVRCLLNIFGVMLYLRVSWVSGQAGVGLGSCIVLLASVVTTITALSTCAICTNGDVKGGGAYFLISRSLGPEFGGSIGIIFSIANAVGAAMYIVGFAESFRDVLIDYNIGTIFDGGLWDVRVIGFVTCVILMGIVFIGSEFESKMQLGLLVILLVSIANYVFGSFFPPNEIAMNRGATGYSLDTLQSNFMPHFTENNTFFSVFSVYFPAATGIMAGANISGDLANPQQAIPLGTLLAILVTTIVYLLTVWMTGSTVVAFSNGTEPAVFNNSYFVPPDCTPDCPFGLVSYYQVVEMSSFWGPLITAGIFAATLSSALASLVSAPKVFQAVCKDRLFPRIDYFAKTYGKNEEPKRAYVLGFFLAMGIVAIGDLNVIAPIISNFFLGSYALINYACF 620

[Close]

BLAST of slc12a-5 vs. Ensembl Celegans
Match: nkcc-1 (Na-K-Cl Cotransporter homolog [Source:UniProtKB/TrEMBL;Acc:L8E912])

HSP 1 Score: 186.808 bits (473), Expect = 1.022e-48
Identity = 135/403 (33.50%), Postives = 223/403 (55.33%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNP--------WIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGT----------------------CTPEI---LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            V+FG   GVF  C++NIFGV+++LR  W+ G AG+GL   I++L  ++  I  LS   +C    ++ GG YFL+S  LG     S+G ++    AV +++Y  GF ES   +L   N         W  + IG    +IL+G+   G ++  ++QL LL+IL +++ +++ GSF        + G  GYS++T ++N    FT  NTFFSVF V+FP ATG+ AG N+SGDL NP+++IPLGTL AI V+ ++Y+      G T                      CTP+    L     +    +F GPL+  G++ ++LS+AL  + +AP++ + + +    P   +  + +GKN+ P  + ++   + +  + IG++N++ PI++  FL +YA ++YA F
Sbjct:  242 VKFGWIQGVFVRCLLNIFGVMLYLRVSWVSGQAGVGLGSCIVLLASVVTTITALSTCAICTNGDVKGGGAYFLISRSLGPEFGGSIGIIFSIANAVGAAMYIVGFAESFRDVLIDYNIGTIFDGGLWDVRVIGFVTCVILMGIVFIGSEFESKMQLGLLVILLVSIANYVFGSFFPPNEIAMNRGATGYSLDTLQSNFMPHFTENNTFFSVFSVYFPAATGIMAGANISGDLANPQQAIPLGTLLAILVTTIVYLLTVWMTGSTVVAFSNGTEPAVFNNSYFVPPDCTPDCPFGLVSYYQVVEMSSFWGPLITAGIFAATLSSALASLVSAPKVFQAVCKDRLFPRIDYFAKTYGKNEEPKRAYVLGFFLAMGIVAIGDLNVIAPIISNFFLGSYALINYACF 644

[Close]

BLAST of slc12a-5 vs. Ensembl Fly
Match: CG12773 (gene:FBgn0024365 transcript:FBtr0342738)

HSP 1 Score: 388.267 bits (996), Expect = 9.171e-124
Identity = 258/644 (40.06%), Postives = 391/644 (60.71%), Query Frame = 1

Query:  325 ENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYT-NPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFK--AINHSKQSKGVKVSHQIGVD-------------TKSGSNSDGFTHST--------GSNLENSSLDKEYSSCEELDRLFP--ERISYGATAETNSDNSFP--KINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGV-AEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDAL 2169
            E   KPWW++NF +++ V FGTWDGVFTSC+IN+FGV++FLR+GW+V  AG+  +VLII  T++IAL+++LSAIG+CERC++ESGGVYFL++H LGSR   ++G LYCFGQAV  +L   GFGES++ L+G   + W  +G     +++L  +N+ GVKWVI+LQ +LL+IL I+ LDF+VGSF     S G  G++   F  N   ++    ++F VFGVFFPT TGV +GINMSGDLR P   IP GTL+A G S  LY+ F + LG TC    L  D MI+ KV+ +  LLL G+YVSS+S+ LG +   PR+L+ IA+ + +PG   LG+  G NKVP++++ I+  +T++FI +G+IN L PIVT PFL+TYA + YAYF LA++FDI+++RE+ F+  A + S +++        G D              +S  NS    H T        G +  N +   E  +  E D      + ++     +   D + P   I   I  + +++YS + NRW SL G F  +L+M  V W Y+L    + F+++ Y+G   P + PG+ AEF+  + +  +      +  N+  +++++   P +   P  + +++ D+  R  YH +  ++  R+ID +
Sbjct:   73 EQGDKPWWRSNFFISQPVLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIFCTVVIALVSVLSAIGICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGLVGLEGSKWAIRGFATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGSFTSEA-SGGFNGWASGNFVENLWPKYDDGYSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFLGATCQRSFLYTDYMISVKVSAVHFLLLAGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLYAMAIVALVTVTFIIVGDINFLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREERFRIQASSPSYETRRYGSVSDTGNDLDLLFPDRVRHKNLQSPQNSP--LHQTVPLEFDNEGPSTSNQAQSSERRTGHEADTTLAVEQAVAQAGVEQDQGDEAEPIAPIRPPIHSKTKNWYSGYCNRWASLLGAFTKLLVMLLVNWYYALTCFLVVFVVWFYVGTANPAVKPGLTAEFNFFAWLKSVIFRCFGKRMNEYEQIVVTPSCPGVDLSPTQLNEQNEDFRPRPNYHHSSVIEG-RLIDDI 712

[Close]

BLAST of slc12a-5 vs. Ensembl Fly
Match: CG12773 (gene:FBgn0024365 transcript:FBtr0070235)

HSP 1 Score: 388.267 bits (996), Expect = 9.171e-124
Identity = 258/644 (40.06%), Postives = 391/644 (60.71%), Query Frame = 1

Query:  325 ENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYT-NPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFK--AINHSKQSKGVKVSHQIGVD-------------TKSGSNSDGFTHST--------GSNLENSSLDKEYSSCEELDRLFP--ERISYGATAETNSDNSFP--KINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGV-AEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDAL 2169
            E   KPWW++NF +++ V FGTWDGVFTSC+IN+FGV++FLR+GW+V  AG+  +VLII  T++IAL+++LSAIG+CERC++ESGGVYFL++H LGSR   ++G LYCFGQAV  +L   GFGES++ L+G   + W  +G     +++L  +N+ GVKWVI+LQ +LL+IL I+ LDF+VGSF     S G  G++   F  N   ++    ++F VFGVFFPT TGV +GINMSGDLR P   IP GTL+A G S  LY+ F + LG TC    L  D MI+ KV+ +  LLL G+YVSS+S+ LG +   PR+L+ IA+ + +PG   LG+  G NKVP++++ I+  +T++FI +G+IN L PIVT PFL+TYA + YAYF LA++FDI+++RE+ F+  A + S +++        G D              +S  NS    H T        G +  N +   E  +  E D      + ++     +   D + P   I   I  + +++YS + NRW SL G F  +L+M  V W Y+L    + F+++ Y+G   P + PG+ AEF+  + +  +      +  N+  +++++   P +   P  + +++ D+  R  YH +  ++  R+ID +
Sbjct:   73 EQGDKPWWRSNFFISQPVLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIFCTVVIALVSVLSAIGICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGLVGLEGSKWAIRGFATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGSFTSEA-SGGFNGWASGNFVENLWPKYDDGYSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFLGATCQRSFLYTDYMISVKVSAVHFLLLAGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLYAMAIVALVTVTFIIVGDINFLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREERFRIQASSPSYETRRYGSVSDTGNDLDLLFPDRVRHKNLQSPQNSP--LHQTVPLEFDNEGPSTSNQAQSSERRTGHEADTTLAVEQAVAQAGVEQDQGDEAEPIAPIRPPIHSKTKNWYSGYCNRWASLLGAFTKLLVMLLVNWYYALTCFLVVFVVWFYVGTANPAVKPGLTAEFNFFAWLKSVIFRCFGKRMNEYEQIVVTPSCPGVDLSPTQLNEQNEDFRPRPNYHHSSVIEG-RLIDDI 712

[Close]

BLAST of slc12a-5 vs. Ensembl Fly
Match: CG12773 (gene:FBgn0024365 transcript:FBtr0332287)

HSP 1 Score: 379.022 bits (972), Expect = 2.819e-120
Identity = 257/644 (39.91%), Postives = 390/644 (60.56%), Query Frame = 1

Query:  325 ENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYT-NPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFK--AINHSKQSKGVKVSHQIGVD-------------TKSGSNSDGFTHST--------GSNLENSSLDKEYSSCEELDRLFP--ERISYGATAETNSDNSFP--KINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGV-AEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDAL 2169
            E   KPW ++NF +++ V FGTWDGVFTSC+IN+FGV++FLR+GW+V  AG+  +VLII  T++IAL+++LSAIG+CERC++ESGGVYFL++H LGSR   ++G LYCFGQAV  +L   GFGES++ L+G   + W  +G     +++L  +N+ GVKWVI+LQ +LL+IL I+ LDF+VGSF     S G  G++   F  N   ++    ++F VFGVFFPT TGV +GINMSGDLR P   IP GTL+A G S  LY+ F + LG TC    L  D MI+ KV+ +  LLL G+YVSS+S+ LG +   PR+L+ IA+ + +PG   LG+  G NKVP++++ I+  +T++FI +G+IN L PIVT PFL+TYA + YAYF LA++FDI+++RE+ F+  A + S +++        G D              +S  NS    H T        G +  N +   E  +  E D      + ++     +   D + P   I   I  + +++YS + NRW SL G F  +L+M  V W Y+L    + F+++ Y+G   P + PG+ AEF+  + +  +      +  N+  +++++   P +   P  + +++ D+  R  YH +  ++  R+ID +
Sbjct:   73 EQGDKPW-RSNFFISQPVLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIFCTVVIALVSVLSAIGICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGLVGLEGSKWAIRGFATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGSFTSEA-SGGFNGWASGNFVENLWPKYDDGYSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFLGATCQRSFLYTDYMISVKVSAVHFLLLAGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLYAMAIVALVTVTFIIVGDINFLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREERFRIQASSPSYETRRYGSVSDTGNDLDLLFPDRVRHKNLQSPQNSP--LHQTVPLEFDNEGPSTSNQAQSSERRTGHEADTTLAVEQAVAQAGVEQDQGDEAEPIAPIRPPIHSKTKNWYSGYCNRWASLLGAFTKLLVMLLVNWYYALTCFLVVFVVWFYVGTANPAVKPGLTAEFNFFAWLKSVIFRCFGKRMNEYEQIVVTPSCPGVDLSPTQLNEQNEDFRPRPNYHHSSVIEG-RLIDDI 711

[Close]

BLAST of slc12a-5 vs. Ensembl Fly
Match: Ncc69 (gene:FBgn0036279 transcript:FBtr0333840)

HSP 1 Score: 155.992 bits (393), Expect = 1.083e-38
Identity = 134/430 (31.16%), Postives = 226/430 (52.56%), Query Frame = 1

Query:  313 NRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPW--------IAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV----KRTPSLGVVGYSIETFRNNTHARFTHE-----NTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGT---------------------CTPEI----LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            N+DPE+          +L   ++FG   GV   C++NI+GV++FLR  W+VG AG+    ++I+ T  +  I  LS   +     I+ GG Y+++S  LG     S+G ++    AVA ++Y  GF ES+ +++  T  W          + IG   +++LL + + G++W  + Q+ LL+IL +A+ DF++GSF+        + G +GY+   F+NN  A +  E     + FFSVF +FFP ATG+ AG N+SGDL++P+KSIP GT+ AI ++   Y+   +  G T                     C P      LQ    +   V+  GPL+  G Y ++LS+AL  + +AP++ + + +    P   +  + +GKN  PV   ++   I  +FI IG +N++ P+++  FL  Y  ++++ F
Sbjct:  198 NQDPESG---------ILNGVLKFGWIKGVLVRCLLNIWGVMLFLRLSWVVGQAGVIEGFVLILTTTAVTTITALSMSAISTNGVIKGGGTYYMISRSLGPEFGGSIGLIFSLANAVACAMYVVGFCESMLAMMT-TFGWEIIDGGVQDVRIIGCITILLLLIIVVVGMEWEAKAQIGLLIILLVAIGDFVIGSFIGPKSDAEMAKGFLGYNATLFKNNLFADYRPEKGGIQHDFFSVFAIFFPAATGILAGANISGDLKDPQKSIPKGTILAIVITTGTYLIMVLQCGATVARDATGNLSDVVNGTFAFLDCQPGECNYGLQNSFQVIELVSAFGPLIYAGCYAATLSSALASLVSAPKVFQALCKDELYPKIVWFAKGYGKNNEPVRGYVLTFIIACAFILIGELNLIAPLISNFFLAAYMLINFSTF 617

[Close]

BLAST of slc12a-5 vs. Ensembl Fly
Match: Ncc69 (gene:FBgn0036279 transcript:FBtr0333842)

HSP 1 Score: 155.992 bits (393), Expect = 1.157e-38
Identity = 134/430 (31.16%), Postives = 226/430 (52.56%), Query Frame = 1

Query:  313 NRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPW--------IAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV----KRTPSLGVVGYSIETFRNNTHARFTHE-----NTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGT---------------------CTPEI----LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            N+DPE+          +L   ++FG   GV   C++NI+GV++FLR  W+VG AG+    ++I+ T  +  I  LS   +     I+ GG Y+++S  LG     S+G ++    AVA ++Y  GF ES+ +++  T  W          + IG   +++LL + + G++W  + Q+ LL+IL +A+ DF++GSF+        + G +GY+   F+NN  A +  E     + FFSVF +FFP ATG+ AG N+SGDL++P+KSIP GT+ AI ++   Y+   +  G T                     C P      LQ    +   V+  GPL+  G Y ++LS+AL  + +AP++ + + +    P   +  + +GKN  PV   ++   I  +FI IG +N++ P+++  FL  Y  ++++ F
Sbjct:  198 NQDPESG---------ILNGVLKFGWIKGVLVRCLLNIWGVMLFLRLSWVVGQAGVIEGFVLILTTTAVTTITALSMSAISTNGVIKGGGTYYMISRSLGPEFGGSIGLIFSLANAVACAMYVVGFCESMLAMMT-TFGWEIIDGGVQDVRIIGCITILLLLIIVVVGMEWEAKAQIGLLIILLVAIGDFVIGSFIGPKSDAEMAKGFLGYNATLFKNNLFADYRPEKGGIQHDFFSVFAIFFPAATGILAGANISGDLKDPQKSIPKGTILAIVITTGTYLIMVLQCGATVARDATGNLSDVVNGTFAFLDCQPGECNYGLQNSFQVIELVSAFGPLIYAGCYAATLSSALASLVSAPKVFQALCKDELYPKIVWFAKGYGKNNEPVRGYVLTFIIACAFILIGELNLIAPLISNFFLAAYMLINFSTF 617

[Close]

BLAST of slc12a-5 vs. Ensembl Zebrafish
Match: slc12a8 (solute carrier family 12 member 8 [Source:ZFIN;Acc:ZDB-GENE-030131-5654])

HSP 1 Score: 309.686 bits (792), Expect = 6.156e-94
Identity = 252/683 (36.90%), Postives = 381/683 (55.78%), Query Frame = 1

Query:  307 LFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIR-KRREDLF---------KAINHSKQSKGVKVSHQI--------------------------------GVDTKSGS-----NSDGFTHSTGSNLENSSLDKEYSSCEELDR-------LFPERISYGATAETNSDNSFP---------KINK----------EIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQA 2133
            LF+ D + +   W        E V FGTWDGVFT+CMINIFGVV+FLRTGW+VG  G+ L +L++ L +++AL+ ++S +G+ E C + +GGVY ++S VLG R+  +VG LY FGQ VA ++Y +GF ESI+ +L   + W+ +GI V +L+ LLG+NL GVKW++RLQL+LL IL ++ LDF++G+F    P  G VGYS +  R NT   +T   TFF+VFGVFFP ATGV AG NMS DL+ P+ +IP+GTL+A+  S+ LY+ F   LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  AFLG+  G NK PV ++ +   IT+ FIFIG +N+L PIVT  F++TY+ + Y YF + K+++++ ++R+ L           +  H +   G  +S  +                                G  TK  +     NS G   ++ + L+    ++E      LD        L    +  G     +  NS P         KI++          EI     S Y+ F N W+SL G     ++MF ++W Y+LI I    +L+IYIG  +PGL  G A  FS    +      +  +N   + +++++  +  +  E   +T+E+ D+  R +YH +
Sbjct:    8 LFHEDAQVQLFVW--------EPVLFGTWDGVFTTCMINIFGVVLFLRTGWLVGNTGVFLGMLLVSLVVLVALVTVMSGVGVSECCSVGNGGVYSMISTVLGGRIGGTVGLLYVFGQCVAGAMYITGFAESIAQVLSLQSTWVVRGISVAVLLGLLGINLAGVKWIVRLQLVLLGILAMSTLDFVIGTFSHLDPEHGFVGYSEKLLRKNTLPDYTAGETFFTVFGVFFPAATGVMAGFNMSSDLQRPEHNIPVGTLAAVCTSWFLYLVFVFLLGAICTREALRYDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQERVIPVLAFLGKGRGPNKTPVAAICLTSLITMGFIFIGQVNVLAPIVTINFMLTYSVIDYCYFCVVKTYELQVQQRKKLISRSSSRKSLVSSTHPRYGSGGAISDPVNGTLLQFTKDMDQIFPLPSTEEQRASPASKARGRKTKIPAKEMLMNSFGLDLNSNAPLDKGKDERELEQAAGLDDDTSSQIGLIESDLKMGNQMNLSLPNSGPAELEQLPKEKIDRNGSETNLEGSEIRSIQSSVYARFCNPWVSLIGALCSFMIMFIIQWMYALINISAALILFIYIGTTSPGLPTGAASHFSFFKWLKTSLHNLGRQNGALQDQIVVTPSLSAVGMETRQLTEENADFALRDRYHHS 682

[Close]

BLAST of slc12a-5 vs. Ensembl Zebrafish
Match: slc12a8 (solute carrier family 12 member 8 [Source:ZFIN;Acc:ZDB-GENE-030131-5654])

HSP 1 Score: 165.622 bits (418), Expect = 7.070e-46
Identity = 127/246 (51.63%), Postives = 175/246 (71.14%), Query Frame = 1

Query:  307 LFNRDPENKK---KPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGD 1035
            LF+ D +  +   +PWWK    + E V FGTWDGVFT+CMINIFGVV+FLRTGW+VG  G+ L +L++ L +++AL+ ++S +G+ E C + +GGVY ++S VLG R+  +VG LY FGQ VA ++Y +GF ESI+ +L   + W+ +GI V +L+ LLG+NL GVKW++RLQL+LL IL ++ LDF++G+F    P  G VGYS +  R NT   +T   TFF+VFGVFFP ATGV AG NMS D
Sbjct:    8 LFHEDAQGSQINAQPWWKVQLFVWEPVLFGTWDGVFTTCMINIFGVVLFLRTGWLVGNTGVFLGMLLVSLVVLVALVTVMSGVGVSECCSVGNGGVYSMISTVLGGRIGGTVGLLYVFGQCVAGAMYITGFAESIAQVLSLQSTWVVRGISVAVLLGLLGINLAGVKWIVRLQLVLLGILAMSTLDFVIGTFSHLDPEHGFVGYSEKLLRKNTLPDYTAGETFFTVFGVFFPAATGVMAGFNMSSD 253

[Close]

BLAST of slc12a-5 vs. Ensembl Zebrafish
Match: slc12a10.3 (solute carrier family 12 member 10, tandem duplicate 3 [Source:ZFIN;Acc:ZDB-GENE-060503-518])

HSP 1 Score: 146.747 bits (369), Expect = 1.011e-35
Identity = 124/411 (30.17%), Postives = 213/411 (51.82%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPW-IAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFT-HENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEI-------LQKDN--------------------------------MITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            V+FG   GV   CM+NI+GV++FLR  W+   AG+ L+ +II +++ I  I   S   +    K+ SGG YFL+S  LG  +   +G L+ F  A+A SL   GF E++  +L   +     + IG   + ILL +   G+ W  + Q+L  + L I++ ++ VG+ +  TP   ++G  GY  E F +N    F   + +FF +F +FFP+ATG+ +G+N+ GDL++P   IP GTL AI  + V Y+  AI +  +   +        L  D+                                 I    +  G L+  G++ ++LS+ALG + +AP++ + + +    P   F G+ +GKN+ P+   L++  I ++FI IG++N + P+++  FL +Y  ++++ F
Sbjct:   77 VRFGWVLGVMIRCMLNIWGVIMFLRLPWITSQAGIILTYVIIFMSVTITTITATSVSAISTNGKVYSGGTYFLISRSLGPELGAPIGLLFSFANALACSLNTVGFAETVRDVLKMVDDVNDVRIIGTITVCILLLITFAGMAWEAKAQILFFIALLISLANYFVGTLLPPTPEKQAVGFFGYRAEIFVDNLLPSFRGKDGSFFRMFSIFFPSATGILSGVNICGDLKDPSGGIPKGTLLAIFWTTVSYLLIAITVAASVVRDASGNLNDSLALDSSIQCSGLGCKLGWNFDHCEQNHTCSFGLANYFQILTTASGTGHLITIGIFAATLSSALGFLVSAPKIFQCLCKDNIYPYIGFFGKGYGKNQEPLRGYLLMFFIALAFILIGDLNTIAPLISNFFLCSYGLINFSCF 487

[Close]

BLAST of slc12a-5 vs. Ensembl Zebrafish
Match: slc12a10.3 (solute carrier family 12 member 10, tandem duplicate 3 [Source:ZFIN;Acc:ZDB-GENE-060503-518])

HSP 1 Score: 146.747 bits (369), Expect = 1.207e-35
Identity = 124/411 (30.17%), Postives = 213/411 (51.82%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPW-IAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFT-HENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEI-------LQKDN--------------------------------MITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            V+FG   GV   CM+NI+GV++FLR  W+   AG+ L+ +II +++ I  I   S   +    K+ SGG YFL+S  LG  +   +G L+ F  A+A SL   GF E++  +L   +     + IG   + ILL +   G+ W  + Q+L  + L I++ ++ VG+ +  TP   ++G  GY  E F +N    F   + +FF +F +FFP+ATG+ +G+N+ GDL++P   IP GTL AI  + V Y+  AI +  +   +        L  D+                                 I    +  G L+  G++ ++LS+ALG + +AP++ + + +    P   F G+ +GKN+ P+   L++  I ++FI IG++N + P+++  FL +Y  ++++ F
Sbjct:  108 VRFGWVLGVMIRCMLNIWGVIMFLRLPWITSQAGIILTYVIIFMSVTITTITATSVSAISTNGKVYSGGTYFLISRSLGPELGAPIGLLFSFANALACSLNTVGFAETVRDVLKMVDDVNDVRIIGTITVCILLLITFAGMAWEAKAQILFFIALLISLANYFVGTLLPPTPEKQAVGFFGYRAEIFVDNLLPSFRGKDGSFFRMFSIFFPSATGILSGVNICGDLKDPSGGIPKGTLLAIFWTTVSYLLIAITVAASVVRDASGNLNDSLALDSSIQCSGLGCKLGWNFDHCEQNHTCSFGLANYFQILTTASGTGHLITIGIFAATLSSALGFLVSAPKIFQCLCKDNIYPYIGFFGKGYGKNQEPLRGYLLMFFIALAFILIGDLNTIAPLISNFFLCSYGLINFSCF 518

[Close]

BLAST of slc12a-5 vs. Ensembl Zebrafish
Match: slc12a10.1 (solute carrier family 12 member 10, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-060503-330])

HSP 1 Score: 146.362 bits (368), Expect = 1.550e-35
Identity = 125/420 (29.76%), Postives = 216/420 (51.43%), Query Frame = 1

Query:  367 TESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWI------AKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFT-HENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALG----------------------------------------GTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            +E V+FG   GV   CM+NI+GV++FLR  W+   AG+ L+ LII++++++  I  LS   +    ++ SGG YF++S  LG  +   +G ++ F  A+A +L   GF E++  LL   N  I       + IG   +  LL ++L G++W  + Q+L  L+L ++  ++ VGS +  TP   S+G   Y  E F  N    +   +  FF +F +FFP+A G+ AG N+SGDL+ P+ +IP GTL AI  + + Y+  +  +G                                        G+C+   L     +  +V+  GPL+  G++ ++LS+AL  + +AP++ + +      P   F G+ +GKN  P+ + L+   I + FI I  +N + P+++  FL +YA ++++ F
Sbjct:  139 SEPVRFGWVTGVMIRCMLNIWGVILFLRLSWITSQAGILLTWLIILMSVLVTSITALSVSAISTNGRVSSGGAYFMISRTLGPELGGPIGVVFSFANALACALNTVGFSETVRDLLIENNSQIVDSVNDVRIIGSITVTALLLISLAGMEWESKTQILFFLVLMVSFTNYFVGSVIPATPQKQSIGFFSYRSEIFVENLFPDWRGPDGDFFRMFAIFFPSAIGILAGANISGDLKEPEIAIPRGTLMAIFCTTISYLAISSTVGACVLRDASGNMNDSLPLNFTEACDSLSCSLGWNFTECEQSGSCSYG-LSNSFQVLVQVSGFGPLIYAGIFAATLSSALAFLVSAPKIFQCLCRDNIYPYIGFFGKGYGKNSEPLRAYLLCYIIAMCFILIAELNTIAPLISNFFLCSYALINFSCF 557

[Close]

BLAST of slc12a-5 vs. Ensembl Xenopus
Match: SLC12A2 (solute carrier family 12 member 2 [Source:NCBI gene;Acc:100038244])

HSP 1 Score: 154.066 bits (388), Expect = 8.300e-38
Identity = 134/419 (31.98%), Postives = 226/419 (53.94%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV---KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALG---------------------------------GTCTPEI---LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF--VLAKS 1491
            V+FG   GV   CM+NI+GV++F+R  W+VG AG+GL+V++I +  ++  I  LS   +     +  GG Y+L+S  LG     ++G ++ F  AVA ++Y  GF E++  LL      +       + IG   +++LLG+++ G++W  + Q++LL+IL +A++DF +G+ +    + P  G  GY  + F  N    F    TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL AI ++ V+YM  A+++G                                  +C  E    L     + + V+   PL+  G++ ++LS+AL  + +AP++ + + +    PG     + +GKN  P+   L+   I + FI I  +N++ PI++  FL +YA ++++ F   LAKS
Sbjct:  213 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLTVVVISMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKENGALMVDDINDIRIIGAITVVLLLGISVAGMEWEAKAQIVLLVILLLAIVDFFIGTVIPSEDKKPK-GFFGYKADIFSENFGPDFREGETFFSVFAIFFPAATGILAGANISGDLADPQHAIPRGTLLAILITTVVYMGVAVSVGSCVVRDASGDVNSTLSAAMTNCTTAACNLNYDFSSCGHECKYGLMNSFQVMSMVSGFAPLITAGIFSATLSSALASLVSAPKVFQALCKDNIYPGLQMFAKGYGKNNEPLRGYLLTFIIALGFILIAELNLIAPIISNFFLASYALINFSVFHASLAKS 630

[Close]

BLAST of slc12a-5 vs. Ensembl Xenopus
Match: SLC12A2 (solute carrier family 12 member 2 [Source:NCBI gene;Acc:100038244])

HSP 1 Score: 154.066 bits (388), Expect = 9.085e-38
Identity = 134/419 (31.98%), Postives = 226/419 (53.94%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV---KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALG---------------------------------GTCTPEI---LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF--VLAKS 1491
            V+FG   GV   CM+NI+GV++F+R  W+VG AG+GL+V++I +  ++  I  LS   +     +  GG Y+L+S  LG     ++G ++ F  AVA ++Y  GF E++  LL      +       + IG   +++LLG+++ G++W  + Q++LL+IL +A++DF +G+ +    + P  G  GY  + F  N    F    TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL AI ++ V+YM  A+++G                                  +C  E    L     + + V+   PL+  G++ ++LS+AL  + +AP++ + + +    PG     + +GKN  P+   L+   I + FI I  +N++ PI++  FL +YA ++++ F   LAKS
Sbjct:  225 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLTVVVISMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKENGALMVDDINDIRIIGAITVVLLLGISVAGMEWEAKAQIVLLVILLLAIVDFFIGTVIPSEDKKPK-GFFGYKADIFSENFGPDFREGETFFSVFAIFFPAATGILAGANISGDLADPQHAIPRGTLLAILITTVVYMGVAVSVGSCVVRDASGDVNSTLSAAMTNCTTAACNLNYDFSSCGHECKYGLMNSFQVMSMVSGFAPLITAGIFSATLSSALASLVSAPKVFQALCKDNIYPGLQMFAKGYGKNNEPLRGYLLTFIIALGFILIAELNLIAPIISNFFLASYALINFSVFHASLAKS 642

[Close]

BLAST of slc12a-5 vs. Ensembl Xenopus
Match: SLC12A2 (solute carrier family 12 member 2 [Source:NCBI gene;Acc:100038244])

HSP 1 Score: 153.68 bits (387), Expect = 9.758e-38
Identity = 134/419 (31.98%), Postives = 226/419 (53.94%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV---KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALG---------------------------------GTCTPEI---LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF--VLAKS 1491
            V+FG   GV   CM+NI+GV++F+R  W+VG AG+GL+V++I +  ++  I  LS   +     +  GG Y+L+S  LG     ++G ++ F  AVA ++Y  GF E++  LL      +       + IG   +++LLG+++ G++W  + Q++LL+IL +A++DF +G+ +    + P  G  GY  + F  N    F    TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL AI ++ V+YM  A+++G                                  +C  E    L     + + V+   PL+  G++ ++LS+AL  + +AP++ + + +    PG     + +GKN  P+   L+   I + FI I  +N++ PI++  FL +YA ++++ F   LAKS
Sbjct:  231 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLTVVVISMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKENGALMVDDINDIRIIGAITVVLLLGISVAGMEWEAKAQIVLLVILLLAIVDFFIGTVIPSEDKKPK-GFFGYKADIFSENFGPDFREGETFFSVFAIFFPAATGILAGANISGDLADPQHAIPRGTLLAILITTVVYMGVAVSVGSCVVRDASGDVNSTLSAAMTNCTTAACNLNYDFSSCGHECKYGLMNSFQVMSMVSGFAPLITAGIFSATLSSALASLVSAPKVFQALCKDNIYPGLQMFAKGYGKNNEPLRGYLLTFIIALGFILIAELNLIAPIISNFFLASYALINFSVFHASLAKS 648

[Close]

BLAST of slc12a-5 vs. Ensembl Xenopus
Match: SLC12A2 (solute carrier family 12 member 2 [Source:NCBI gene;Acc:100038244])

HSP 1 Score: 153.68 bits (387), Expect = 1.023e-37
Identity = 134/419 (31.98%), Postives = 226/419 (53.94%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV---KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALG---------------------------------GTCTPEI---LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF--VLAKS 1491
            V+FG   GV   CM+NI+GV++F+R  W+VG AG+GL+V++I +  ++  I  LS   +     +  GG Y+L+S  LG     ++G ++ F  AVA ++Y  GF E++  LL      +       + IG   +++LLG+++ G++W  + Q++LL+IL +A++DF +G+ +    + P  G  GY  + F  N    F    TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL AI ++ V+YM  A+++G                                  +C  E    L     + + V+   PL+  G++ ++LS+AL  + +AP++ + + +    PG     + +GKN  P+   L+   I + FI I  +N++ PI++  FL +YA ++++ F   LAKS
Sbjct:  217 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLTVVVISMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKENGALMVDDINDIRIIGAITVVLLLGISVAGMEWEAKAQIVLLVILLLAIVDFFIGTVIPSEDKKPK-GFFGYKADIFSENFGPDFREGETFFSVFAIFFPAATGILAGANISGDLADPQHAIPRGTLLAILITTVVYMGVAVSVGSCVVRDASGDVNSTLSAAMTNCTTAACNLNYDFSSCGHECKYGLMNSFQVMSMVSGFAPLITAGIFSATLSSALASLVSAPKVFQALCKDNIYPGLQMFAKGYGKNNEPLRGYLLTFIIALGFILIAELNLIAPIISNFFLASYALINFSVFHASLAKS 634

[Close]

BLAST of slc12a-5 vs. Ensembl Xenopus
Match: SLC12A2 (solute carrier family 12 member 2 [Source:NCBI gene;Acc:100038244])

HSP 1 Score: 153.68 bits (387), Expect = 1.040e-37
Identity = 134/419 (31.98%), Postives = 226/419 (53.94%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV---KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALG---------------------------------GTCTPEI---LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF--VLAKS 1491
            V+FG   GV   CM+NI+GV++F+R  W+VG AG+GL+V++I +  ++  I  LS   +     +  GG Y+L+S  LG     ++G ++ F  AVA ++Y  GF E++  LL      +       + IG   +++LLG+++ G++W  + Q++LL+IL +A++DF +G+ +    + P  G  GY  + F  N    F    TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL AI ++ V+YM  A+++G                                  +C  E    L     + + V+   PL+  G++ ++LS+AL  + +AP++ + + +    PG     + +GKN  P+   L+   I + FI I  +N++ PI++  FL +YA ++++ F   LAKS
Sbjct:  238 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLTVVVISMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKENGALMVDDINDIRIIGAITVVLLLGISVAGMEWEAKAQIVLLVILLLAIVDFFIGTVIPSEDKKPK-GFFGYKADIFSENFGPDFREGETFFSVFAIFFPAATGILAGANISGDLADPQHAIPRGTLLAILITTVVYMGVAVSVGSCVVRDASGDVNSTLSAAMTNCTTAACNLNYDFSSCGHECKYGLMNSFQVMSMVSGFAPLITAGIFSATLSSALASLVSAPKVFQALCKDNIYPGLQMFAKGYGKNNEPLRGYLLTFIIALGFILIAELNLIAPIISNFFLASYALINFSVFHASLAKS 655

[Close]

BLAST of slc12a-5 vs. Ensembl Mouse
Match: Slc12a8 (solute carrier family 12 (potassium/chloride transporters), member 8 [Source:MGI Symbol;Acc:MGI:2443672])

HSP 1 Score: 348.591 bits (893), Expect = 1.490e-108
Identity = 267/690 (38.70%), Postives = 391/690 (56.67%), Query Frame = 1

Query:  331 KKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSF--------DIRKRREDLFKAINHSKQSK----GVKV----------------------------SHQIGVDTKSGSN----------------SDGFTHSTGSNL----------------ENSSLDKEYSS-CEELDRLFPERISYGATAETNSDNSFPKI---NKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCI-SHLPSAIRSRNSNQEREMLISK--KIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVI 2160
            + +PWWK    + E V FGTWDGVFTSCMINIFGVV+FLRTGW+VG  G+ L +L++   +++ALI +LS IG+ E   I SGGVY ++S VLG ++  +VG LY FGQ VA ++Y +GF ESIS LLG  + W  +GI V +L+ LLG+NL GVKW+IRLQLLLLL+L ++ LDF+VGSF    P  G +GYS E  ++N    ++   +FF+VFGVFFP ATGV AG NM GDLR+P  S+PLG+L+A+GVS+ LY+ FA  LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  AFL    G NK PV ++ +   +T++F+ +G +N+L P+VT  F++TY  + Y+YF L+ +          + ++  D      H  Q +    G  V                            S Q+G  ++ G+N                 D F    GS L                E  S  K+ +S  E  D L P+  +       N ++ F K     +EI ++P  FY+   N W+SL G    +L+MF ++W Y+L  +G+  L+Y YIG  +PGL+ G A  FS    + S L  + RS  S QE+ +L     K+   +T+   +T ++ D+  R +YH +  + +++++
Sbjct:   21 QPQPWWKIQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGLLLVSFVVLVALITVLSGIGVAEHGGISSGGVYSMISSVLGGQMGGTVGLLYVFGQCVAGAMYITGFAESISDLLGLGDIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLLLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQSNILPEYSPGESFFTVFGVFFPAATGVMAGFNMGGDLRDPADSVPLGSLAAVGVSWFLYIIFAFLLGAVCTREALRSDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQDKVIPALAFLANGKGPNKTPVAAICLTSLVTMAFVLVGQVNVLAPVVTINFMLTYIMVDYSYFALSMAHCGLAPSPEPVPRQGPDTLHCSEHLLQDRAPSYGSDVPARSLSEGTLLEFTKDMDQFLQPIEELESRQLG--SREGNNPKNQKRKGKKGAKQTLQDSFLLDPGSPLSFPTRTSERLSVAFCGEQESYQKQQTSRSESHDHLVPDLRN---QPRVNREDFFLKCRLQEQEIQRRPSVFYACMCNPWVSLLGALASLLIMFVIQWLYTLASMGVAALVYFYIGQASPGLYLGSASNFSFFQWMKSFLVPSCRSLRSAQEQIILAPSPAKVDMAMTQ---LTQDNADFATRDRYHHSSFLSREQLM 702

[Close]

Query:  331 KKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSF--------DIRKRREDLFKAINHSKQSK----GVKV----------------------------SHQIGVDTKSGSN----------------SDGFTHSTGSNL----------------ENSSLDKEYSS-CEELDRLFPERISYGATAETNSDNSFPKI---NKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCI-SHLPSAIRSRNSNQEREMLISK--KIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVI 2160
            + +PWWK    + E V FGTWDGVFTSCMINIFGVV+FLRTGW+VG  G+ L +L++   +++ALI +LS IG+ E   I SGGVY ++S VLG ++  +VG LY FGQ VA ++Y +GF ESIS LLG  + W  +GI V +L+ LLG+NL GVKW+IRLQLLLLL+L ++ LDF+VGSF    P  G +GYS E  ++N    ++   +FF+VFGVFFP ATGV AG NM GDLR+P  S+PLG+L+A+GVS+ LY+ FA  LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  AFL    G NK PV ++ +   +T++F+ +G +N+L P+VT  F++TY  + Y+YF L+ +          + ++  D      H  Q +    G  V                            S Q+G  ++ G+N                 D F    GS L                E  S  K+ +S  E  D L P+  +       N ++ F K     +EI ++P  FY+   N W+SL G    +L+MF ++W Y+L  +G+  L+Y YIG  +PGL+ G A  FS    + S L  + RS  S QE+ +L     K+   +T+   +T ++ D+  R +YH +  + +++++
Sbjct:   21 QPQPWWKIQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGLLLVSFVVLVALITVLSGIGVAEHGGISSGGVYSMISSVLGGQMGGTVGLLYVFGQCVAGAMYITGFAESISDLLGLGDIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLLLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQSNILPEYSPGESFFTVFGVFFPAATGVMAGFNMGGDLRDPADSVPLGSLAAVGVSWFLYIIFAFLLGAVCTREALRSDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQDKVIPALAFLANGKGPNKTPVAAICLTSLVTMAFVLVGQVNVLAPVVTINFMLTYIMVDYSYFALSMAHCGLAPSPEPVPRQGPDTLHCSEHLLQDRAPSYGSDVPARSLSEGTLLEFTKDMDQFLQPIEELESRQLG--SREGNNPKNQKRKGKKGAKQTLQDSFLLDPGSPLSFPTRTSERLSVAFCGEQESYQKQQTSRSESHDHLVPDLRN---QPRVNREDFFLKCRLQEQEIQRRPSVFYACMCNPWVSLLGALASLLIMFVIQWLYTLASMGVAALVYFYIGQASPGLYLGSASNFSFFQWMKSFLVPSCRSLRSAQEQIILAPSPAKVDMAMTQ---LTQDNADFATRDRYHHSSFLSREQLM 702

[Close]

BLAST of slc12a-5 vs. Ensembl Mouse
Match: Slc12a8 (solute carrier family 12 (potassium/chloride transporters), member 8 [Source:MGI Symbol;Acc:MGI:2443672])

HSP 1 Score: 288.5 bits (737), Expect = 3.586e-87
Identity = 225/577 (38.99%), Postives = 312/577 (54.07%), Query Frame = 1

Query:  331 KKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSF--------DIRKRREDLFKAINHSKQSK----GVKV----------------------------SHQIGVDTKSGSN----------------SDGFTHSTGSNL----------------ENSSLDKEYSS-CEELDRLFPERISYGATAETNSDNSFPKI---NKEIIKQPRSFYSIFINRWISLFG 1833
            + +PWWK    + E V FGTWDGVFTSCMINIFGVV+FLRTGW+VG  G+ L +L++   +++ALI +LS IG+ E   I SGGVY ++S VLG ++  +VG LY FGQ VA ++Y +GF ESIS LLG  + W  +GI V +L+ LLG+NL GVKW+IRLQLLLLL+L ++ LDF+VGSF    P  G +GYS E  ++N    ++   +FF+VFGVFFP ATGV AG NM GDLR+P  S+PLG+L+A+GVS+ LY+ FA  LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  AFL                             +N+L P+VT  F++TY  + Y+YF L+ +          + ++  D      H  Q +    G  V                            S Q+G  ++ G+N                 D F    GS L                E  S  K+ +S  E  D L P+  +       N ++ F K     +EI ++P  FY+   N W+SL G
Sbjct:   21 QPQPWWKIQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGLLLVSFVVLVALITVLSGIGVAEHGGISSGGVYSMISSVLGGQMGGTVGLLYVFGQCVAGAMYITGFAESISDLLGLGDIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLLLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQSNILPEYSPGESFFTVFGVFFPAATGVMAGFNMGGDLRDPADSVPLGSLAAVGVSWFLYIIFAFLLGAVCTREALRSDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQDKVIPALAFLAN--------------------------GVNVLAPVVTINFMLTYIMVDYSYFALSMAHCGLAPSPEPVPRQGPDTLHCSEHLLQDRAPSYGSDVPARSLSEGTLLEFTKDMDQFLQPIEELESRQLG--SREGNNPKNQKRKGKKGAKQTLQDSFLLDPGSPLSFPTRTSERLSVAFCGEQESYQKQQTSRSESHDHLVPDLRN---QPRVNREDFFLKCRLQEQEIQRRPSVFYACMCNPWVSLLG 566

[Close]

BLAST of slc12a-5 vs. Ensembl Mouse
Match: Slc12a8 (solute carrier family 12 (potassium/chloride transporters), member 8 [Source:MGI Symbol;Acc:MGI:2443672])

HSP 1 Score: 280.796 bits (717), Expect = 7.139e-84
Identity = 241/677 (35.60%), Postives = 351/677 (51.85%), Query Frame = 1

Query:  370 ESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSF--------DIRKRREDLFKAINHSKQSK----GVKV----------------------------SHQIGVDTKSGSN----------------SDGFTHSTGSNL----------------ENSSLDKEYSS-CEELDRLFPERISYGATAETNSDNSFPKI---NKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCI-SHLPSAIRSRNSNQEREMLISK--KIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVI 2160
            E V FGTWDGVFTSCMINIFGVV+FLRTGW+VG  G+ L +L++   +++ALI +LS IG+ E   I SGGVY ++S VLG ++  +VG LY FGQ VA ++Y +GF ESIS LLG  + W  +GI V +L+ LLG+NL GVKW+IRLQLLLLL+L ++ LDF+VGSF    P  G +GYS E  ++N    ++   +FF+VFGVFFP ATGV AG NM GDLR+P  S+PLG+L+A+GVS+ LY+ FA  LG  CT E L+ D +I  K                                                  G NK PV ++ +   +T++F+ +G +N+L P+VT  F++TY  + Y+YF L+ +          + ++  D      H  Q +    G  V                            S Q+G  ++ G+N                 D F    GS L                E  S  K+ +S  E  D L P+  +       N ++ F K     +EI ++P  FY+   N W+SL G    +L+MF ++W Y+L  +G+  L+Y YIG  +PGL+ G A  FS    + S L  + RS  S QE+ +L     K+   +T+   +T ++ D+  R +YH +  + +++++
Sbjct:    3 EPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGLLLVSFVVLVALITVLSGIGVAEHGGISSGGVYSMISSVLGGQMGGTVGLLYVFGQCVAGAMYITGFAESISDLLGLGDIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLLLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQSNILPEYSPGESFFTVFGVFFPAATGVMAGFNMGGDLRDPADSVPLGSLAAVGVSWFLYIIFAFLLGAVCTREALRSDFLIAEKK-------------------------------------------------GPNKTPVAAICLTSLVTMAFVLVGQVNVLAPVVTINFMLTYIMVDYSYFALSMAHCGLAPSPEPVPRQGPDTLHCSEHLLQDRAPSYGSDVPARSLSEGTLLEFTKDMDQFLQPIEELESRQLG--SREGNNPKNQKRKGKKGAKQTLQDSFLLDPGSPLSFPTRTSERLSVAFCGEQESYQKQQTSRSESHDHLVPDLRN---QPRVNREDFFLKCRLQEQEIQRRPSVFYACMCNPWVSLLGALASLLIMFVIQWLYTLASMGVAALVYFYIGQASPGLYLGSASNFSFFQWMKSFLVPSCRSLRSAQEQIILAPSPAKVDMAMTQ---LTQDNADFATRDRYHHSSFLSREQLM 622

[Close]

BLAST of slc12a-5 vs. Ensembl Mouse
Match: Slc12a8 (solute carrier family 12 (potassium/chloride transporters), member 8 [Source:MGI Symbol;Acc:MGI:2443672])

HSP 1 Score: 176.022 bits (445), Expect = 2.397e-47
Identity = 143/463 (30.89%), Postives = 227/463 (49.03%), Query Frame = 1

Query: 1012 AGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSF--------DIRKRREDLFKAINHSKQSK----GVKV----------------------------SHQIGVDTKSGSN----------------SDGFTHSTGSNL----------------ENSSLDKEYSS-CEELDRLFPERISYGATAETNSDNSFPKI---NKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCI-SHLPSAIRSRNSNQEREMLISK--KIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVI 2160
            AG NM GDLR+P  S+PLG+L+A+GVS+ LY+ FA  LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  AFL    G NK PV ++ +   +T++F+ +G +N+L P+VT  F++TY  + Y+YF L+ +          + ++  D      H  Q +    G  V                            S Q+G  ++ G+N                 D F    GS L                E  S  K+ +S  E  D L P+          N ++ F K     +EI ++P  FY+   N W+SL G    +L+MF ++W Y+L  +G+  L+Y YIG  +PGL+ G A  FS    + S L  + RS  S QE+ +L     K+   +T+   +T ++ D+  R +YH +  + +++++
Sbjct:    2 AGFNMGGDLRDPADSVPLGSLAAVGVSWFLYIIFAFLLGAVCTREALRSDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQDKVIPALAFLANGKGPNKTPVAAICLTSLVTMAFVLVGQVNVLAPVVTINFMLTYIMVDYSYFALSMAHCGLAPSPEPVPRQGPDTLHCSEHLLQDRAPSYGSDVPARSLSEGTLLEFTKDMDQFLQPIEELESRQLG--SREGNNPKNQKRKGKKGAKQTLQDSFLLDPGSPLSFPTRTSERLSVAFCGEQESYQKQQTSRSESHDHLVPD---LRNQPRVNREDFFLKCRLQEQEIQRRPSVFYACMCNPWVSLLGALASLLIMFVIQWLYTLASMGVAALVYFYIGQASPGLYLGSASNFSFFQWMKSFLVPSCRSLRSAQEQIILAPSPAKVDMAMTQ---LTQDNADFATRDRYHHSSFLSREQLM 456

[Close]

BLAST of slc12a-5 vs. UniProt/SwissProt
Match: sp|Q6A4L1|S12A8_XENLA (Solute carrier family 12 member 8 OS=Xenopus laevis OX=8355 GN=slc12a8 PE=2 SV=1)

HSP 1 Score: 385.185 bits (988), Expect = 1.544e-121
Identity = 272/696 (39.08%), Postives = 395/696 (56.75%), Query Frame = 1

Query:  307 LFNRDPENKK---KPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIR--------------------------------------KRREDLFKAINHS----------------KQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNL------ENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINK-------------EIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPG-VAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVID 2163
            LF+ D +  +   +PWWK    + E V FGTWDGVFTSCMINIFGVV+FLRTGW+VG  G+ L ++++   +++AL+ +LS IG+CERC I SGGVY ++S VLG +V  ++G LY FGQ VA ++Y +GF ESIS LL   N W+ +GI + +L+ LLG+NL GVKW+IRLQLLL L+L ++ LDF++GSF    P  G VGYS E  RNNT   +T   +FF+VFGVFFP ATGV  G NMSGDL+ P  +IPLG+L+AIG S+ LY+ F   LG  CT E L+ + MI  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  +FLGR  G NK PV ++ I   +T++F+FIG +N+L PIVT  F++TY+ + Y+YF +  S+ ++                                      K    LFK  NH+                K SK  K + Q   D+       G  H   S L      EN S + +    E+ ++      S    +E + D   P   +             EI +   SFY+ F N W++  G  + I++MF ++W Y+L+ +G+  +LY+YIG V PGL PG  A FS  + I      +  R  + + + +++  +  +  E   +T+E+ D+  RG+YH +  + + + ID
Sbjct:   25 LFHEDAQVSQLQSRPWWKIQLFVWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGIVLVSFVILVALVTVLSGIGVCERCSIGSGGVYSMVSTVLGGKVGGTIGVLYIFGQCVAGAMYITGFAESISDLLNLENMWVVRGISLAVLVGLLGINLAGVKWIIRLQLLLFLLLAVSTLDFVIGSFTHLDPENGFVGYSEELLRNNTFPDYTPGESFFTVFGVFFPAATGVMVGFNMSGDLQRPSINIPLGSLAAIGTSWFLYVVFVFLLGAICTREFLRYEFMIAEKVSLVGGLFLLGLYISSLASCMGGLYGAPRILQCIAQEKVIPALSFLGRGKGPNKTPVAAIFITGLLTMAFVFIGQVNVLAPIVTINFMLTYSAVDYSYFSVTMSYKMQHSPKKNGRPNSRVMSSTQPLILNKSTSYGSNGTLLEFTKDMNQLFKP-NHTEAPESTSSQEKDPKMFKFSKPRKPAKQTLQDSFQLDLHQGPEHGLESRLLVTDLAENESQNSKAEITEDKNQGVDPTESDEPDSEEDVDIQQPTEEQKGDSTVAQKVPEFEIQELSTSFYAKFCNHWVAFLGAILSIVIMFVIQWIYALVNLGVAIILYLYIGRVNPGLNPGAAANFSFFAWIRQGARTL-CRKPHPKEQFVVTPSLLSVGMETTQLTEENEDFASRGRYHHSSIITQGQFID 718

[Close]

BLAST of slc12a-5 vs. UniProt/SwissProt
Match: sp|Q8VI23|S12A8_MOUSE (Solute carrier family 12 member 8 OS=Mus musculus OX=10090 GN=Slc12a8 PE=2 SV=2)

HSP 1 Score: 348.591 bits (893), Expect = 1.042e-107
Identity = 267/690 (38.70%), Postives = 391/690 (56.67%), Query Frame = 1

Query:  331 KKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSF--------DIRKRREDLFKAINHSKQSK----GVKV----------------------------SHQIGVDTKSGSN----------------SDGFTHSTGSNL----------------ENSSLDKEYSS-CEELDRLFPERISYGATAETNSDNSFPKI---NKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCI-SHLPSAIRSRNSNQEREMLISK--KIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVI 2160
            + +PWWK    + E V FGTWDGVFTSCMINIFGVV+FLRTGW+VG  G+ L +L++   +++ALI +LS IG+ E   I SGGVY ++S VLG ++  +VG LY FGQ VA ++Y +GF ESIS LLG  + W  +GI V +L+ LLG+NL GVKW+IRLQLLLLL+L ++ LDF+VGSF    P  G +GYS E  ++N    ++   +FF+VFGVFFP ATGV AG NM GDLR+P  S+PLG+L+A+GVS+ LY+ FA  LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  AFL    G NK PV ++ +   +T++F+ +G +N+L P+VT  F++TY  + Y+YF L+ +          + ++  D      H  Q +    G  V                            S Q+G  ++ G+N                 D F    GS L                E  S  K+ +S  E  D L P+  +       N ++ F K     +EI ++P  FY+   N W+SL G    +L+MF ++W Y+L  +G+  L+Y YIG  +PGL+ G A  FS    + S L  + RS  S QE+ +L     K+   +T+   +T ++ D+  R +YH +  + +++++
Sbjct:   21 QPQPWWKIQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGLLLVSFVVLVALITVLSGIGVAEHGGISSGGVYSMISSVLGGQMGGTVGLLYVFGQCVAGAMYITGFAESISDLLGLGDIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLLLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQSNILPEYSPGESFFTVFGVFFPAATGVMAGFNMGGDLRDPADSVPLGSLAAVGVSWFLYIIFAFLLGAVCTREALRSDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQDKVIPALAFLANGKGPNKTPVAAICLTSLVTMAFVLVGQVNVLAPVVTINFMLTYIMVDYSYFALSMAHCGLAPSPEPVPRQGPDTLHCSEHLLQDRAPSYGSDVPARSLSEGTLLEFTKDMDQFLQPIEELESRQLG--SREGNNPKNQKRKGKKGAKQTLQDSFLLDPGSPLSFPTRTSERLSVAFCGEQESYQKQQTSRSESHDHLVPDLRN---QPRVNREDFFLKCRLQEQEIQRRPSVFYACMCNPWVSLLGALASLLIMFVIQWLYTLASMGVAALVYFYIGQASPGLYLGSASNFSFFQWMKSFLVPSCRSLRSAQEQIILAPSPAKVDMAMTQ---LTQDNADFATRDRYHHSSFLSREQLM 702

[Close]

BLAST of slc12a-5 vs. UniProt/SwissProt
Match: sp|A0AV02|S12A8_HUMAN (Solute carrier family 12 member 8 OS=Homo sapiens OX=9606 GN=SLC12A8 PE=1 SV=4)

HSP 1 Score: 313.538 bits (802), Expect = 1.991e-94
Identity = 217/493 (44.02%), Postives = 312/493 (63.29%), Query Frame = 1

Query:  313 NRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAK-SFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHST--GSNLE-NSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIK 1779
             +D   + +PWWKT   + E V FGTWDGVFTSCMINIFGVV+FLRTGW+VG  G+ L + ++   +++AL+ +LS IG+ ER  I SGGVY ++S VLG +   ++G LY FGQ VA ++Y +GF ESIS LLG  N W  +GI V +L+ LLG+NL GVKW+IRLQLLLL +L ++ LDF+VGSF    P  G +GYS E  +NNT   ++   +FF+VFGVFFP ATGV AG NM GDLR P  SIPLG+L+A+G+S+ LY+ F   LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  A LG+  G NK PV ++ +   +T++F+F+G +N+L PIVT  F++TY  + Y+YF L+  S  +    E + +     + ++G+  S  + ++      S+G       G+ LE    +D+      +L+   P +     T E+    S  K  K+ ++
Sbjct:   16 QQDALAQPQPWWKTQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGMFLVSFVILVALVTVLSGIGVGERSSIGSGGVYSMISSVLGGQTGGTIGLLYVFGQCVAGAMYITGFAESISDLLGLGNIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLFLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQNNTLPDYSPGESFFTVFGVFFPAATGVMAGFNMGGDLREPAASIPLGSLAAVGISWFLYIIFVFLLGAICTREALRYDFLIAEKVSLMGFLFLLGLYISSLASCMGGLYGAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQVNVLAPIVTINFMLTYVAVDYSYFSLSMCSCSLTPVPEPVLR-----EGAEGLHCSEHLLLEKAPSYGSEGPAQRVLEGTLLEFTKDMDQLLQLTRKLESSQPRQGEGNRTPESQKRKS-KKATKQTLQ 502

HSP 2 Score: 80.1073 bits (196), Expect = 3.888e-14
Identity = 46/163 (28.22%), Postives = 94/163 (57.67%), Query Frame = 1

Query: 1687 DRLFPERISYGATAETNSDNSFPK---INKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCI-SHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVI 2160
            ++L PE  +    +E++ ++ F K     +++ ++  SFY+   N W+SL G    +L+MF ++W Y+L+ +G+  ++Y YIG  +PGL  G A  FS    + S L  + RS  S QE +++++  + ++  E   +T E+ D+  R +YH +  +++++++
Sbjct:  553 EQLVPELCN---QSESSGEDFFLKSRLQEQDVWRRSTSFYTHMCNPWVSLLGAVGSLLIMFVIQWVYTLVNMGVAAIVYFYIGRASPGLHLGSASNFSFFRWMRSLLLPSCRSLRSPQE-QIILAPSLAKVDMEMTQLTQENADFATRDRYHHSSLVNREQLM 711

[Close]

BLAST of slc12a-5 vs. UniProt/SwissProt
Match: sp|Q8CJI3|S12A8_RAT (Solute carrier family 12 member 8 OS=Rattus norvegicus OX=10116 GN=Slc12a8 PE=2 SV=1)

HSP 1 Score: 311.227 bits (796), Expect = 1.551e-93
Identity = 256/691 (37.05%), Postives = 375/691 (54.27%), Query Frame = 1

Query:  331 KKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKS----IPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFV-------LAKSFDIRKRR-EDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDG----FTHSTGSNLE--------------NSSLDKEYSSCEE-----------LDRLFP--------ERISYGATAETNS------------DNSFPKI------------------NKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCI-SHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVI 2160
            + +PWWK    + E V FGTWDGVFTSCMINIFGVV+FLRTGW+VG  G+ L +L++   +++ALI +LS IG+ E   + SGGVY ++S VLG ++  +VG LY FGQ VA ++Y +GF ESIS LLG  N W  +GI V +L+ LLG+NL GVKW+IRLQLLLL +L ++ LDF+VGSF    P  G +GYS E  ++N    ++   +FF+VFGVFFP ATGV AG NM GDLR P       +P     + G S ++   FA  LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  AFLG   G NK PV ++ +   +T++F+ +G +N+L P+VT  F++TY  + Y+YF        LA+S +   R+  D      H  Q K    +   G DT +GS S+G    FT      L+              N  L  +   C++           LD   P        ER+S  +  E  S            D+  P +                   +++ ++P +FY    N W+SL G    +L+MF ++W Y+L  +G+  L+Y+YIG  +PGL+ G A  FS    + S L  + RS  S +E+ +L        +        +      R +YH++  + +++++
Sbjct:   21 RSQPWWKIQLFMWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGLLLVSFVILVALITVLSGIGVAEHGWMGSGGVYSMISSVLGGQMGGTVGLLYVFGQCVAGAMYLTGFAESISDLLGLGNIWAVRGISVAVLLALLGINLAGVKWIIRLQLLLLSLLAVSTLDFVVGSFTHLDPEHGFIGYSPELLQSNILPEYSPGESFFTVFGVFFPAATGVMAGFNMGGDLREPADQHTPRLPSSCWVSRGFSNII---FAFLLGAVCTREALRSDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQDKVIPALAFLGNGKGPNKTPVAAICLTSLVTMAFVLVGQVNVLAPVVTINFMLTYIAVDYSYFALSMAHCGLAQSPEPMPRQGPDALHCSEHLLQDK----APSYGSDTPAGSLSEGTLLEFTKDMDQLLQPIGGLESQPRSREVNQVLKSQKHKCKKDAKQTLQDSFLLDAESPLSFSMGASERLSVASCGEQESYQNQQTSRSESHDHLVPDLCTQPRANGEDFFLKCRLQEQQVQRRPSAFYVCMCNPWVSLLGALASLLIMFVIQWLYTLASMGVAALVYLYIGQASPGLYLGSASNFSFFQWMKSFLVPSCRSLRSTREQIILAPSPAKVDMAMTQAYPGQWQTSATRERYHRSSFLSREQLM 704

[Close]

BLAST of slc12a-5 vs. UniProt/SwissProt
Match: sp|P55012|S12A2_MOUSE (Solute carrier family 12 member 2 OS=Mus musculus OX=10090 GN=Slc12a2 PE=1 SV=2)

HSP 1 Score: 156.377 bits (394), Expect = 7.886e-38
Identity = 137/420 (32.62%), Postives = 230/420 (54.76%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVK---RTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALG------------GTCTPEI-------------------------LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF--VLAKS 1491
            V+FG   GV   CM+NI+GV++F+R  W+VG AG+GLSV++I +  ++  I  LS   +     +  GG Y+L+S  LG     ++G ++ F  AVA ++Y  GF E++  LL   +  +       + IG   ++ILLG+++ G++W  + Q++LL+IL +A+ DF++G+F+    + P  G  GY  E F  N    F  E TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL AI ++ V+Y+  A+++G             T T E+                         L  +  + + V+   PL+  G++ ++LS+AL  + +AP++ + + +    P      + +GKN  P+   ++   I + FI I  +N++ PI++  FL +YA ++++ F   LAKS
Sbjct:  276 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVVVIAMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIADFVIGTFISLESKKPK-GFFGYKSEIFNENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTVVYIGIAVSVGSCVVRDATGNVNDTITTELTNCTSAACKLNFDFSYCESNTCSYGLMNNFQVMSMVSGFAPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKS 694

[Close]

BLAST of slc12a-5 vs. TrEMBL
Match: A0A0H3YJ24 (Slc12a-5 OS=Schmidtea mediterranea OX=79327 GN=slc12a-5 PE=2 SV=1)

HSP 1 Score: 1112.44 bits (2876), Expect = 0.000e+0
Identity = 668/668 (100.00%), Postives = 668/668 (100.00%), Query Frame = 1

Query:  187 MKNSDGSQDANWSKFGLXXXXXXXXXXXXXXXXXXXXXXXLFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDALAGVGNNK 2190
            MKNSDGSQDANWSKFGLTKSRTTTKSESEEYKEEDAKENELFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVLIIILTMIIALIAILSAIGLCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKGIGVGILIILLGVNLTGVKWVIRLQLLLLLILFIAVLDFLVGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPVFSLLIIVSITISFIFIGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDALAGVGNNK
Sbjct:    1 MKNSDGSQDANWSKFGLTKSRTTTKSESEEYKEEDAKENELFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVLIIILTMIIALIAILSAIGLCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKGIGVGILIILLGVNLTGVKWVIRLQLLLLLILFIAVLDFLVGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPVFSLLIIVSITISFIFIGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDALAGVGNNK 668

[Close]

BLAST of slc12a-5 vs. TrEMBL
Match: A0A1S3K6X4 (solute carrier family 12 member 8 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106179051 PE=4 SV=1)

HSP 1 Score: 466.463 bits (1199), Expect = 3.573e-150
Identity = 310/667 (46.48%), Postives = 430/667 (64.47%), Query Frame = 1

Query:  307 LFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYT-NPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFK------AINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYG---------------------ATAETNSDNS----------------------------FPK-INKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQ 2136
            LF  D     KPWWK NF ++E V FG WDGVFTSCMINIFG++IFLRTGWMVG AG+GLS+LII LT+ +AL+++LSAIG+CERC++ESGG++FLLSHVLG+++  S+G +YCFGQAV+ SLY  GFGESI++ +    +PWIA+GI   +L++LLG+N+ GVKWVIRLQLLLL IL +AV+DF VGSFV      GV GY      NNT   +    +FFSVFGVFFPTATG  AGINMSGDLRNP K IP+GTL+A+GVS  LY+ F + LG TC  + L++D MI  KVA LG L L GLY+SS+S+ +G +  +PR+L+ IA+   +P   FLG+  G NKVPVF+LL I  I++ FI IGN+NIL PIVT PF++TYA++ +AYF LA SF  RKR+E+ +       AI+      G + S Q   +  + +++ G T    ++L   ++    +   +LD LFPER+ +                      + A+  ++NS                             PK +N EI + PRS+YSIF+NRW+SL G+   +++MFG++W Y+L+ + +  ++YIYI  V PG+FPG+AEFS+L  I    S    R      E++++   P + T    +T+++ D+ +RG+YHQ++
Sbjct:   58 LFAEDQSASSKPWWKLNFFISEPVLFGPWDGVFTSCMINIFGIIIFLRTGWMVGNAGIGLSILIICLTIGVALVSVLSAIGVCERCQMESGGIFFLLSHVLGAKIGASIGVIYCFGQAVSCSLYTMGFGESIAAFIDPDFDPWIARGIAAAVLLLLLGINIAGVKWVIRLQLLLLFILAVAVMDFAVGSFVHTDIEYGVTGYLTINLVNNTAPAYLAGESFFSVFGVFFPTATGAFAGINMSGDLRNPSKDIPVGTLAAVGVSTFLYLMFTMILGSTCARDYLREDYMIAEKVAALGFLFLAGLYISSISSCMGSLYGSPRILQSIAKQNVIPVIKFLGQGRGPNKVPVFALLAITVISLVFICIGNVNILAPIVTMPFMLTYASVDFAYFSLAMSFQKRKRKEERYSSGLLKPAISSVGGGVGGRKSDQ---ENNNANHNYGSTDKVSNDLPPKNIPDNTA---DLDNLFPERLLFDQKHTAVQQKRSPKKQQQGSPVSKAQKQAENSGKEHVDGEHVERGAEADATTELLDKQSGNPKPVNTEIHRMPRSYYSIFVNRWLSLIGSIACLVIMFGIQWIYALVTVSVVLVIYIYISKVNPGVFPGIAEFSLLEWIRDGVSHCCRRGPQPAEEIVVTPSTPAVRTFAAQLTEDNDDFANRGRYHQSE 718

[Close]

BLAST of slc12a-5 vs. TrEMBL
Match: A0A1S3K5V4 (solute carrier family 12 member 8 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106179051 PE=4 SV=1)

HSP 1 Score: 466.463 bits (1199), Expect = 3.740e-150
Identity = 310/667 (46.48%), Postives = 430/667 (64.47%), Query Frame = 1

Query:  307 LFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYT-NPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFK------AINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYG---------------------ATAETNSDNS----------------------------FPK-INKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQ 2136
            LF  D     KPWWK NF ++E V FG WDGVFTSCMINIFG++IFLRTGWMVG AG+GLS+LII LT+ +AL+++LSAIG+CERC++ESGG++FLLSHVLG+++  S+G +YCFGQAV+ SLY  GFGESI++ +    +PWIA+GI   +L++LLG+N+ GVKWVIRLQLLLL IL +AV+DF VGSFV      GV GY      NNT   +    +FFSVFGVFFPTATG  AGINMSGDLRNP K IP+GTL+A+GVS  LY+ F + LG TC  + L++D MI  KVA LG L L GLY+SS+S+ +G +  +PR+L+ IA+   +P   FLG+  G NKVPVF+LL I  I++ FI IGN+NIL PIVT PF++TYA++ +AYF LA SF  RKR+E+ +       AI+      G + S Q   +  + +++ G T    ++L   ++    +   +LD LFPER+ +                      + A+  ++NS                             PK +N EI + PRS+YSIF+NRW+SL G+   +++MFG++W Y+L+ + +  ++YIYI  V PG+FPG+AEFS+L  I    S    R      E++++   P + T    +T+++ D+ +RG+YHQ++
Sbjct:   65 LFAEDQSASSKPWWKLNFFISEPVLFGPWDGVFTSCMINIFGIIIFLRTGWMVGNAGIGLSILIICLTIGVALVSVLSAIGVCERCQMESGGIFFLLSHVLGAKIGASIGVIYCFGQAVSCSLYTMGFGESIAAFIDPDFDPWIARGIAAAVLLLLLGINIAGVKWVIRLQLLLLFILAVAVMDFAVGSFVHTDIEYGVTGYLTINLVNNTAPAYLAGESFFSVFGVFFPTATGAFAGINMSGDLRNPSKDIPVGTLAAVGVSTFLYLMFTMILGSTCARDYLREDYMIAEKVAALGFLFLAGLYISSISSCMGSLYGSPRILQSIAKQNVIPVIKFLGQGRGPNKVPVFALLAITVISLVFICIGNVNILAPIVTMPFMLTYASVDFAYFSLAMSFQKRKRKEERYSSGLLKPAISSVGGGVGGRKSDQ---ENNNANHNYGSTDKVSNDLPPKNIPDNTA---DLDNLFPERLLFDQKHTAVQQKRSPKKQQQGSPVSKAQKQAENSGKEHVDGEHVERGAEADATTELLDKQSGNPKPVNTEIHRMPRSYYSIFVNRWLSLIGSIACLVIMFGIQWIYALVTVSVVLVIYIYISKVNPGVFPGIAEFSLLEWIRDGVSHCCRRGPQPAEEIVVTPSTPAVRTFAAQLTEDNDDFANRGRYHQSE 725

[Close]

BLAST of slc12a-5 vs. TrEMBL
Match: A0A2C9K4Y5 (AA_permease domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106051514 PE=4 SV=1)

HSP 1 Score: 449.129 bits (1154), Expect = 1.003e-143
Identity = 286/654 (43.73%), Postives = 407/654 (62.23%), Query Frame = 1

Query:  307 LFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISY---------GATAETNSDNSFPKI--------------------------NKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVID 2163
            L+  +     +PWWK+NF +++ V FGTWDGVFTSC+INI GVVIFLR GW+V  AG+GLSVLI++  + I +I  LSAIG+CERCK+ SGGVYFLLSHVLG+R+  S+G LYCF Q+V  SL   GFGESI +LL   N W+A+GI  G++++LLGVN++GVKWVIRLQL+LLL+LF++++D  VGSFV   PS GV GY+   F NN+   F H   FFSVFG+FF T TGV AGINMSGDL++P  +IP GT++A+G    +++   + LG TC    L  D MI  KV+  G L L GLY+SS+S+ +G +    R+L+ IA    +P   FLG   G NKVPVF L+ I  +T+ FI +G++N L P+VTT FL+TYA + Y+YFVLA S+D R+  E+ F   +  +  +   +S  +       S   G T     N    SL+K      +LD+LFPER+++          +  E + D +  KI                          N EI+KQPRS+YS+  NRW+SLFG  + +++MF  +W ++LI + ++ ++YIYIG  +PG FPG+AEF+    +    +  R      E  ++++ K+P++ T    +T+++ D+  RG+YHQ++ M  +   D
Sbjct:   63 LYREEQAVSSQPWWKSNFFISQPVLFGTWDGVFTSCLINILGVVIFLRMGWIVANAGIGLSVLIVLFGISIIVIVALSAIGVCERCKVGSGGVYFLLSHVLGARIGGSIGILYCFAQSVGCSLSVMGFGESIMTLLKQDNTWVARGIAFGVVLLLLGVNISGVKWVIRLQLILLLVLFLSIMDLWVGSFVHTLPSFGVEGYNDINFVNNSGPDFQHGENFFSVFGLFFSTITGVLAGINMSGDLKDPFHNIPQGTMAALGAGTFVFISIILVLGATCVRSFLLSDYMIAEKVSLFGVLWLAGLYLSSVSSCMGSLYGPSRILQSIANENVIPIIKFLGYGHGPNKVPVFGLICITLVTLLFICVGDVNSLAPVVTTAFLLTYAAVDYSYFVLAMSYDKRRMLEERFGTDSEDRNKEEKAISADL-------SPKKGKTVDVSQN--KDSLEK---FANDLDKLFPERLTHRGHRLLSQSASHLEADFDATKTKIDSEGSPANQPEDLNDTTHLLGVKRTPNTEIVKQPRSWYSVLCNRWLSLFGCLICLVIMFTTQWLFALIELLVFLVIYIYIGRASPGYFPGIAEFNFYEWLKESCNKCRPGYVPPEH-IIVASKMPDVETLEAQLTEDNADFASRGRYHQSEVMKGENFDD 703

[Close]

BLAST of slc12a-5 vs. TrEMBL
Match: V4A5Y4 (AA_permease domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_123579 PE=4 SV=1)

HSP 1 Score: 443.351 bits (1139), Expect = 1.152e-142
Identity = 279/626 (44.57%), Postives = 399/626 (63.74%), Query Frame = 1

Query:  325 ENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPER------------------ISYGATAETNSDNSFPKI----NKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQ 2136
            E    PWWK+NF ++  V FGTWDGVFTSC+INI  VVIFLR GW+VG AG+GLS++ + L++ + LI  LSAIG+CERC++E GGVYFL+SHVLG R+  S+G +YCF QAV+ SL   GFGESI  L+G TNPWIA+ I  G++I+LLG+N+ GVKWV+RLQL+LLL+LF++ +D +VGSFV      GV GY+   F NN+  ++     FFS+FG+FF T TG+ AGINMSGDL++P  +IP GTL+++GV  +LY+ F + LG TC    L  D MI  KV+ +G L L GLY+SS+S+ +G +   PR+L+ IA    +P    LG+  G NKVPV++L++I  + + FI +G +N L P+VTT F++TYA + Y+YF LA S+D RK RE  F+   H ++S                        STGS++ N S++       +LD+LFPER                  IS   T E + D +  K+    N EI KQPRS+YS   NRW+SLFGT + ++L+F ++W Y+L  + ++F +Y YIG  +PG FPG+AEF+    I     +   R      +++++ + P + T    +T+++ D+ +RG+YHQ++
Sbjct:    5 EISDIPWWKSNFFISAPVLFGTWDGVFTSCLINILSVVIFLRMGWIVGNAGIGLSIVTVFLSVSVVLIVALSAIGVCERCRMEGGGVYFLISHVLGGRIGGSIGIVYCFAQAVSCSLSVMGFGESIMELIGQTNPWIARSIAFGVVILLLGINVAGVKWVVRLQLVLLLVLFLSAMDLIVGSFVHTDVENGVTGYTEVNFVNNSGPQYAEGENFFSIFGLFFATVTGILAGINMSGDLQDPFYNIPRGTLASLGVGTILYISFILVLGATCLRSYLLDDYMIAEKVSIVGFLWLAGLYLSSVSSCMGSLYGPPRILQSIANENVIPFMKILGKGRGPNKVPVYALIVITLVVLLFICVGQVNTLAPVVTTAFMLTYAAIDYSYFALAMSYDRRKTREAKFQQNGHIRKS------------------------STGSDITNGSVENIR---HDLDKLFPERMSQRGQHSHLRRQDSRNTISGATTPEADFDATKKKLKKAPNTEITKQPRSWYSALCNRWLSLFGTLVCLVLLFMIQWMYALGELTVFFAIYFYIGQASPGYFPGIAEFNFYEWIKECLQSCCRRGPTPPEQIIVAPRTPAVETLAAQLTEDNEDFANRGRYHQSE 603

[Close]

BLAST of slc12a-5 vs. Ensembl Cavefish
Match: slc12a8 (solute carrier family 12 member 8 [Source:NCBI gene;Acc:103045409])

HSP 1 Score: 332.413 bits (851), Expect = 6.542e-103
Identity = 261/667 (39.13%), Postives = 390/667 (58.47%), Query Frame = 1

Query:  316 RDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIR-KRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLE-NSSLDKEY-----SSCEELDRLFPERISYGATA--------------ETNSDNSFPK------INKEIIKQPRSFYSIFI-------NRWISL----------------FGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPG-VAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKM-DKDRVI 2160
            +D +   +PWWK    + E V FGTWDGVFT+CMINIFGVV+FLRTGW+VG  G+ L +L++ L + +AL+ ++S IG+CERC + SGGVY ++S VLG RV  +VG LY FGQ VA ++Y +GF ESI+ +L   + W  +GI V +L+ LLG+NL GVKW++RLQL+LL IL ++ LDF++G+F    P  G +GYS E  R NT   +T   TFF+VFGVFFP ATGV AG NMS DL+ P+ +IP+GTL+AI  S+ LY+ F   LG  CT + L+ D +I  KV+ +G L L GLYVSSL++ +GG+  APR+L+ IA+   +P  AFLG+  G NK PV ++ +   I+++FIFIG +NIL PIVT  F++TY+ + Y+YF +AKS++++ K R  LF+    S +   V  SHQ       GSN      S G+ LE    +++ +      S EE     P   ++G  A              + NS++   K      + + +     +   I++        R +SL                 G+ + + +   ++W Y+L+ I +  LL++YIG  +PGL  G  A FS    I    S +       + +++++  + E+  E   +T+E+ D+  R +YHQ+  +   DR++
Sbjct:   16 QDSQMHAQPWWKVKLFVWEPVLFGTWDGVFTTCMINIFGVVLFLRTGWLVGNTGVLLGMLLVSLVVQVALVTVMSGIGVCERCSVGSGGVYSMISTVLGGRVGGTVGLLYVFGQCVAGAMYITGFAESIADVLTVQSVWAVRGISVAVLLGLLGINLAGVKWIVRLQLVLLAILAVSTLDFVIGTFSHLDPEHGFIGYSDEVLRKNTLPDYTAGETFFTVFGVFFPAATGVMAGFNMSSDLQKPEHNIPVGTLAAIFTSWFLYLVFVFLLGAICTRDALRYDFLIAEKVSLVGFLFLLGLYVSSLASCMGGLYGAPRVLQCIAQERVIPALAFLGQGKGPNKTPVAAICLTSLISMAFIFIGQVNILAPIVTINFMLTYSFIDYSYFCVAKSYELQVKERRPLFE--RPSSRKALVMSSHQC-----YGSNGAMRNTSNGTLLEFTKDMNQIFPLPNTDSTEEEKAPNPAAKAWGRKAKVPAKETLSSSFGLDLNSNSPLEKEKDEKQLEQSVGLDDETSSQIWLMESESGGERKLSLPTRDPVELDQLPRESVLGSIVIMFI---IQWVYALVNISVALLLFLYIGKASPGLPTGAAARFSFFQWIKSFVSNLGREKHELQDQIVVTPSLSEVGMETRQLTEENADFAFRDRYHQSSIITTTDRMV 672

[Close]

BLAST of slc12a-5 vs. Ensembl Cavefish
Match: slc12a8 (solute carrier family 12 member 8 [Source:NCBI gene;Acc:103045409])

HSP 1 Score: 303.908 bits (777), Expect = 8.573e-92
Identity = 220/463 (47.52%), Postives = 310/463 (66.95%), Query Frame = 1

Query:  316 RDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIR-KRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFP 1701
            +D +   +PWWK    + E V FGTWDGVFT+CMINIFGVV+FLRTGW+VG  G+ L +L++ L + +AL+ ++S IG+CERC + SGGVY ++S VLG RV  +VG LY FGQ VA ++Y +GF ESI+ +L   + W  +GI V +L+ LLG+NL GVKW++RLQL+LL IL ++ LDF++G+F    P  G +GYS E  R NT   +T   TFF+VFGVFFP ATGV AG NMS DL+ P+ +IP+GTL+AI  S+ LY+ F   LG  CT + L+ D +I  KV+ +G L L GLYVSSL++ +GG+  APR+L+ IA+   +P  AFLG+  G NK PV ++ +   I+++FIFIG +NIL PIVT  F++TY+ + Y+YF +AKS++++ K R  LF+    S +   V  SHQ       GSN      S G+ LE +         ++++++FP
Sbjct:   14 QDSQMHAQPWWKVKLFVWEPVLFGTWDGVFTTCMINIFGVVLFLRTGWLVGNTGVLLGMLLVSLVVQVALVTVMSGIGVCERCSVGSGGVYSMISTVLGGRVGGTVGLLYVFGQCVAGAMYITGFAESIADVLTVQSVWAVRGISVAVLLGLLGINLAGVKWIVRLQLVLLAILAVSTLDFVIGTFSHLDPEHGFIGYSDEVLRKNTLPDYTAGETFFTVFGVFFPAATGVMAGFNMSSDLQKPEHNIPVGTLAAIFTSWFLYLVFVFLLGAICTRDALRYDFLIAEKVSLVGFLFLLGLYVSSLASCMGGLYGAPRVLQCIAQERVIPALAFLGQGKGPNKTPVAAICLTSLISMAFIFIGQVNILAPIVTINFMLTYSFIDYSYFCVAKSYELQVKERRPLFE--RPSSRKALVMSSHQC-----YGSNGAMRNTSNGTLLEFT---------KDMNQIFP 460

HSP 2 Score: 88.9669 bits (219), Expect = 7.894e-18
Identity = 57/210 (27.14%), Postives = 102/210 (48.57%), Query Frame = 1

Query: 1540 SKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQ-PRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPG-VAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKM-DKDRVI 2160
             K+    ++   +G+D ++ S        +G   + S   ++    ++L R          +AE N     PK+    I+  P SFYS F N W+SL G    I++MF ++W Y+L+ I +  LL++YIG  +PGL  G  A FS    I    S +       + +++++  + E+  E   +T+E+ D+  R +YHQ+  +   DR++
Sbjct:  507 EKEKDEKQLEQSVGLDDETSSQIWLMESESGGERKLSLPTRDPVELDQLPR---------ESAEKNEPK--PKLEVSGIQPLPNSFYSRFCNHWVSLIGVLGSIVIMFIIQWVYALVNISVALLLFLYIGKASPGLPTGAAARFSFFQWIKSFVSNLGREKHELQDQIVVTPSLSEVGMETRQLTEENADFAFRDRYHQSSIITTTDRMV 705

[Close]

BLAST of slc12a-5 vs. Ensembl Cavefish
Match: slc12a8 (solute carrier family 12 member 8 [Source:NCBI gene;Acc:103045409])

HSP 1 Score: 248.054 bits (632), Expect = 1.620e-71
Identity = 196/463 (42.33%), Postives = 275/463 (59.40%), Query Frame = 1

Query:  316 RDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIR-KRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFP 1701
            +D +   +PWWK    + E V FGTWDGVFT+CMINIFGVV+FLRTGW+VG  G+ L +L++ L + +AL+ ++S IG+CERC + SGGVY ++S VLG RV  +VG LY FGQ VA ++Y +GF ESI+ +L   + W  +GI V +L+ LLG+NL GVKW++RLQL+LL IL ++ LDF++G+F    P  G +GYS E  R NT   +T   TFF+VFGVFFP ATGV AG NMS DL+ P+ +IP+GTL+AI  S+ LY+ F   LG  CT + L+ D +I  K                                                  G NK PV ++ +   I+++FIFIG +NIL PIVT  F++TY+ + Y+YF +AKS++++ K R  LF+    S +   V  SHQ       GSN      S G+ LE +         ++++++FP
Sbjct:   14 QDSQMHAQPWWKVKLFVWEPVLFGTWDGVFTTCMINIFGVVLFLRTGWLVGNTGVLLGMLLVSLVVQVALVTVMSGIGVCERCSVGSGGVYSMISTVLGGRVGGTVGLLYVFGQCVAGAMYITGFAESIADVLTVQSVWAVRGISVAVLLGLLGINLAGVKWIVRLQLVLLAILAVSTLDFVIGTFSHLDPEHGFIGYSDEVLRKNTLPDYTAGETFFTVFGVFFPAATGVMAGFNMSSDLQKPEHNIPVGTLAAIFTSWFLYLVFVFLLGAICTRDALRYDFLIAEKK-------------------------------------------------GPNKTPVAAICLTSLISMAFIFIGQVNILAPIVTINFMLTYSFIDYSYFCVAKSYELQVKERRPLFE--RPSSRKALVMSSHQC-----YGSNGAMRNTSNGTLLEFT---------KDMNQIFP 411

HSP 2 Score: 88.9669 bits (219), Expect = 7.139e-18
Identity = 57/210 (27.14%), Postives = 102/210 (48.57%), Query Frame = 1

Query: 1540 SKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQ-PRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPG-VAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKM-DKDRVI 2160
             K+    ++   +G+D ++ S        +G   + S   ++    ++L R          +AE N     PK+    I+  P SFYS F N W+SL G    I++MF ++W Y+L+ I +  LL++YIG  +PGL  G  A FS    I    S +       + +++++  + E+  E   +T+E+ D+  R +YHQ+  +   DR++
Sbjct:  458 EKEKDEKQLEQSVGLDDETSSQIWLMESESGGERKLSLPTRDPVELDQLPR---------ESAEKNEPK--PKLEVSGIQPLPNSFYSRFCNHWVSLIGVLGSIVIMFIIQWVYALVNISVALLLFLYIGKASPGLPTGAAARFSFFQWIKSFVSNLGREKHELQDQIVVTPSLSEVGMETRQLTEENADFAFRDRYHQSSIITTTDRMV 656

[Close]

BLAST of slc12a-5 vs. Ensembl Cavefish
Match: SLC12A2 (solute carrier family 12 member 2-like [Source:NCBI gene;Acc:103037139])

HSP 1 Score: 157.918 bits (398), Expect = 2.605e-39
Identity = 131/414 (31.64%), Postives = 223/414 (53.86%), Query Frame = 1

Query:  373 SVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV---KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGG-------------------TCTPEI------------------LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            +V+FG   GV   CM+NI+GV++F+R  W+VG AG+ LS  II++ +++  I  LS   +     +  GG Y+L+S  LG     S+G ++ F  AVA ++Y  GF E++  LL   +  +       + +G   +I+LLG+++ G++W  + Q++LL+IL  A+ ++ +GSF+    + P  G  GY++     N    F  E TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL +I ++ V+Y+  A + G                     CT                     L  D  + + V+  GPL+  G++ ++LS+AL  + +AP++ + + +    PG     + +GKN  P+   ++   I ++FI I  +NI+ PI++  FL +YA ++++ F
Sbjct:  194 TVKFGWIKGVLIRCMLNIWGVMLFIRMSWIVGQAGIALSCGIILMAVVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVELLDSVDALMTDEINDIRIVGTLTIILLLGISVAGMEWEAKAQIVLLIILVAAIFNYFIGSFIPMESKEPK-GFFGYNVAILLENMGPDFRDEETFFSVFAIFFPAATGILAGANISGDLSDPQSAIPKGTLLSILITGVVYIAVAFSNGACILRDATGEDNDTIIGSLENCTDAACTLGYDFSICKEGGCKYGLMNDFQVMSLVSVFGPLITAGIFSATLSSALASLVSAPKVFQALCKDNIYPGLRIFAKGYGKNNEPLRGYVLTFFIGLAFILIAELNIIAPIISNFFLASYALINFSVF 606

[Close]

BLAST of slc12a-5 vs. Ensembl Cavefish
Match: slc12a1 (solute carrier family 12 member 1 [Source:ZFIN;Acc:ZDB-GENE-080130-3])

HSP 1 Score: 147.902 bits (372), Expect = 3.937e-36
Identity = 123/413 (29.78%), Postives = 215/413 (52.06%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEI-------------------------------------LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            V+FG   GV   CM+NI+GV++F+R  W+ G AG+GL ++II+L+ ++  +  +S   +C    +  GG Y+L+S  LG     S+G ++ F  AVA ++Y  GF E++  LL   N  +       + +G   +++LLG+   G++W  + Q++LL+IL +A+ +  VG+ +  T    S G   Y       N    F    TFFSVF +FFP ATG+ AG N+SGDLR+P+++IP+GTL AI ++ + Y+  A+ +  T   +                                      L  +  +   V+  GPL+  G + +++S+AL  + +AP++ + + +        F  +  GKN  P+   ++   I ++FI I  +N++ PI++  FL +YA ++++ F
Sbjct:  112 VKFGWIKGVLVRCMLNIWGVMLFIRLSWVFGQAGVGLGIIIILLSCVVTTLTCISMSAICTNGVVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFSETVVDLLKVNNAIMVDEVNDIRIVGCITVVLLLGIVGAGMEWEAKAQIVLLVILLVAIANVFVGTAIPATEDKKSKGFFNYQASIMAENFTPDFRDGETFFSVFAIFFPAATGILAGANISGDLRDPQEAIPIGTLLAIFITGITYLGIALCVSATVVRDATGNVNNTITYGANCNFSSACDFGYDFSPCETTKCKYGLMNNFQVMTMVSGFGPLITAGTFSATISSALASLVSAPKVFQALCKDNIYKALIFFAKGHGKNNEPIRGYVLTFIIAVAFILIAELNVIAPIISNFFLASYALINFSCF 524

[Close]

BLAST of slc12a-5 vs. Ensembl Sea Lamprey
Match: slc12a8 (solute carrier family 12 member 8 [Source:ZFIN;Acc:ZDB-GENE-030131-5654])

HSP 1 Score: 365.925 bits (938), Expect = 4.296e-116
Identity = 264/665 (39.70%), Postives = 395/665 (59.40%), Query Frame = 1

Query:  334 KKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSK-----GVKVSHQIGVDTKSGSNS-DGFT---------HSTGSNLENSSLDKEYS---------SCEELDRLF-------------PERISY-----GATAETN---------------SDNSFPKINK-------EIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQA 2133
            + PWW++ F + E V FG WDGVFTSCMINIFGVVIFLRTGW+VG AG+ L VL++ L +++AL+++LS IG+CERCKI SGG+YF++S VLG +V  ++G LY FGQ V  +LY +GF ES++   G +N W  +GI +G+++ LLG+NL GVKWVIRLQL+LL +L +++  + V          G VGY+ E  +NNT   +T   +FF+VFGVFFPTATGV AG NMSGDL+ P K+IP+G+L+AIG+++ LY+ F + LG TCT E L+ D MI  KV+ +G L L GLY+SSL++ + G+  APR+L+ IA+   +P    LGR  G NK PV+++ ++  IT +FIF+G +NIL PIVT  FL+TYAT+ Y+YF LA ++D ++ R     +     Q K     G+      G +  +G  S   FT          S+GS+  +++  ++ +         + E L   F             PE+  Y       +AE++               SD+S  +  K       EI +    FY+   NRW+SL G  + +++M  ++W Y+L+ + +  LL IYIG  +PGL PG+A +F+  + I  L   +  R    + + +++  +  +      +T E+ D+  R ++HQ+
Sbjct:   23 RTPWWRSQFFVREPVLFGMWDGVFTSCMINIFGVVIFLRTGWLVGNAGVLLGVLMVFLVILVALVSVLSGIGVCERCKIGSGGIYFMISTVLGGKVGGTIGLLYVFGQCVVGALYVTGFAESVADTFGLSNIWAVRGIAIGVVLGLLGINLAGVKWVIRLQLVLLALLAVSIFFYTVRVHAHMNAENGFVGYTEELLKNNTFPDYTPGESFFTVFGVFFPTATGVMAGFNMSGDLKTPSKNIPVGSLAAIGITWFLYLVFVLLLGATCTREALRVDFMIAEKVSLVGFLFLVGLYISSLASCMTGLYGAPRILQCIAQERVIPIIEVLGRGHGPNKTPVYAIGVVGVITTAFIFVGQVNILAPIVTINFLLTYATIDYSYFALAMTYDEQQERRLRLASGGVKMQPKPQVAGGISNGDGNGANRAAGQGSLQEFTKDMDLLFPKESSGSSKVDANSGQQQAPRRGRSRKPAKETLQDSFMLDLEGQVFKTNDPEKRKYVDPMNDVSAESDEQTIHQDPLQDLASSSDSSQQETQKSRNPWEAEISQMSNKFYAKLCNRWVSLLGMLVCLVVMMVIQWIYALVNLVVALLLLIYIGQSSPGLPPGIATDFNFFTWIKSLFLRMCRRGPAPKEQFVVTPSLLPMGLSTTQLTQENADFASRDRFHQS 687

[Close]

BLAST of slc12a-5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003053.1 (pep scaffold:Pmarinus_7.0:GL478333:5880:33924:-1 gene:ENSPMAG00000002656.1 transcript:ENSPMAT00000003053.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 136.346 bits (342), Expect = 3.337e-33
Identity = 125/421 (29.69%), Postives = 216/421 (51.31%), Query Frame = 1

Query:  370 ESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPE-------------------------------ILQKDN------------MITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            E V FG + GV    ++NI+GV+++LR  W+   AG+GL+ +I+++ +II  I+ LS   +    K+  GG YF++S  LG  +    G LY F  AV  +++  GF E++  +L  +N  +       + IGV  +  LLG+ + G+ W  + QL+  +++ I++L++L+G+ +  TP   S G   Y+ + F  N    F     FF +FGVFFP  TG+ AG N+ GDL++P  +IP GTL AI  + + Y+     +G     +                               + + D              + A V+   PL+  G++ ++LS+AL  + +AP+  + +A     PG +  G+ FG+N+ P+F  L+   I+I FI I  +NI+ PI++  F+++Y  L+++ F
Sbjct:   97 EPVLFGWFRGVMMRVIVNIWGVLMYLRLPWITAQAGIGLTWVIVLVAVIITSISGLSISAISNNGKVARGGTYFMVSRTLGYELGAPFGILYSFAAAVGIAMHTVGFAETLRDILHASNLIMVDKVNDIRIIGVITVTFLLGIAMAGLAWENKAQLIFFVLIIISLLNYLLGTVIPATPEKMSKGFFNYNAKIFAENFTPVF-RNTEFFRLFGVFFPAVTGILAGANICGDLKDPASAIPKGTLLAILTTALSYLIINTTIGAVMLRDASGLLSDSFAWVCNGSSKLACELGWNFTACSLFRPDTTSPCTFGFVNNYQVMAMVSAWAPLIYAGIFGAALSSALANLISAPKCFQGVARDNIYPGISIFGKGFGRNQEPLFGYLLAYLISICFIIIAELNIIAPIISCFFIISYTILNFSCF 516

[Close]

BLAST of slc12a-5 vs. Ensembl Sea Lamprey
Match: slc12a9 (solute carrier family 12 member 9 [Source:NCBI gene;Acc:793341])

HSP 1 Score: 91.6633 bits (226), Expect = 3.143e-19
Identity = 60/202 (29.70%), Postives = 103/202 (50.99%), Query Frame = 1

Query:  883 TPSLGVVGYSIETFRNNTHARFTHE------NTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYA 1470
            T +L   G S+ T  +N    +T +       TF SVF + F   TG+ AG NMSGDL++P  +IP GT++A+  +F +Y+     +  +C  ++L  + +    +   GP +  G+Y +SLSAA+  +  A R+L  +A          + +   ++  P  ++L+   +    +F G +N +  IVT  FL+ YAT+  A
Sbjct:  216 TMNLNYSGPSLGTLHDNLKEHYTQDYTTGVTMTFASVFAIMFNGCTGIMAGSNMSGDLKDPSYAIPRGTIAAVVFTFCVYVLLCFMVSCSCPRDLLLYNYVFMRDINVWGPFVTIGIYAASLSAAMSCLIGASRVLHAVALDDIFGVLLKVVKRTSRSGNPWVAVLVSWFLVQLVLFAGQLNTIAGIVTVFFLIAYATVDLA 417

HSP 2 Score: 51.2174 bits (121), Expect = 9.394e-7
Identity = 33/108 (30.56%), Postives = 63/108 (58.33%), Query Frame = 1

Query:  379 QFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESI 702
            +  T+ GV    ++++F VV++LR G++VG AGL  S+L+ ++  +I  + +LS   +     ++ GGVYF++S  LG     S+G ++      +S+++  G  E+I
Sbjct:   28 KLNTFFGVVVPTLLSMFSVVLYLRIGFVVGQAGLLESLLMFVVAYVIIGLTVLSVCAISTNGAVQGGGVYFMISRALGPEFGGSIGVMFFLANVCSSAVFLLGLTEAI 135

[Close]

BLAST of slc12a-5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001762.1 (pep scaffold:Pmarinus_7.0:GL484736:821:6283:1 gene:ENSPMAG00000001597.1 transcript:ENSPMAT00000001762.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 75.0998 bits (183), Expect = 1.328e-16
Identity = 39/91 (42.86%), Postives = 56/91 (61.54%), Query Frame = 1

Query:  865 GSFVKRT---PSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALG 1128
            G+F+  T    S G  GY  + F  N    F +  TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GT+ AI ++ + Y+  A++ G
Sbjct:   20 GTFIPPTEEKKSRGYFGYQAKIFSENMGPDFQNGETFFSVFAIFFPAATGILAGANISGDLADPQAAIPRGTMLAILITTITYLGVAMSTG 110

[Close]

BLAST of slc12a-5 vs. Ensembl Sea Lamprey
Match: slc12a4 (solute carrier family 12 member 4 [Source:ZFIN;Acc:ZDB-GENE-090218-27])

HSP 1 Score: 60.8474 bits (146), Expect = 9.460e-10
Identity = 39/117 (33.33%), Postives = 63/117 (53.85%), Query Frame = 1

Query:  379 QFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNP 729
            + GT+ GV+  C+ NIFGV++FLR  W+VG AG+  +  I+ +     ++  +S   +     + +GG YF++S  LG     +VG  +  G   A+S+Y  G   +I  LL Y  P
Sbjct:    2 RMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGVLEAFCIVFVCCCCTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAASMYILG---AIEILLTYIVP 115

HSP 2 Score: 60.077 bits (144), Expect = 1.540e-9
Identity = 27/69 (39.13%), Postives = 46/69 (66.67%), Query Frame = 1

Query:  958 NTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDN 1164
             +F ++ G+FFP+ TG+ AG N SGDL++ +KSIP+GT+ AI  +  +Y+  ++ L G C   ++ +D 
Sbjct:  303 TSFTALVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTIMAIATTSTVYLT-SVILFGACVEGVVLRDK 370

[Close]

BLAST of slc12a-5 vs. Ensembl Yeast
Match: VHC1 (Vacuolar membrane cation-chloride cotransporter (CCC); likely mediates K+ and Cl- cotransport into the vacuole; has a role in potassium homeostasis and salt tolerance; localizes to sites of contact between the vacuole and mitochondria (vCLAMPs); similar to mammalian electroneutral Na(+)-(K+)-C1- cotransporter family [Source:SGD;Acc:S000000439])

HSP 1 Score: 96.2857 bits (238), Expect = 7.131e-21
Identity = 106/418 (25.36%), Postives = 183/418 (43.78%), Query Frame = 1

Query:  319 DPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESI------------SSLLGYTNP---WIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGY---SIETFRNNTHARFTH---------ENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKS 1491
            DP+N  K             + GT+DGVF    +N+  +++FLR G+++G  G+  ++ +++L+  I L+  LS   +     +  GG Y+++S  LG     S+G ++  GQ   + + A G  E +             + LG   P   W        IL +   V   G + V R   +L L+L  ++    + + ++   + G + Y   S +TF +N     T          + TF  +FGVFFP   G+ AG  MS +LR P KSIP GTL  +  +F+ Y     ++G +     L  +  I   ++ +  ++  G   +SL + + G+  A  +L+ IA+   +PG                  LI   I        ++N +   +T  FLMT+  ++ A F+L  S
Sbjct:   54 DPDNPNKD------------KLGTYDGVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISAISTNGTVRGGGAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYNLGYSAQGEPPAALGELLPRGHWHEFTYATVILFLCFSVAFVGSQTVSRAGNILFLVLAASIFSIPLSALIRSPFTEGGISYTGPSWQTFHDNLLPHLTKGAAGSLLKGKETFNDLFGVFFPATAGIFAGAGMSSELRKPSKSIPKGTLWGLLFTFICYAVVVFSMGCSIPRRSLYDEVQIIQTISSVQWVIFMGEMATSLFSIIVGMLGAAYVLEAIAKDNIIPGLEIFAHS-------PLYSLIFTWILTQLCLFSDVNKIATFITMTFLMTFVVMNLACFLLGIS 452

[Close]

BLAST of slc12a-5 vs. Ensembl Nematostella
Match: EDO46430 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ45])

HSP 1 Score: 401.364 bits (1030), Expect = 8.938e-130
Identity = 274/661 (41.45%), Postives = 383/661 (57.94%), Query Frame = 1

Query:  337 KPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFV--LYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDI-----------RKRRE------------------------------------DLFKAINHSKQSKGVKVSHQIGVD--TKSGSNSDG------FTHSTGSNLENSSLDKEYSSCEELDRLFP-ERISYGATAETNSDNSFPK---INKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGV-AEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQA 2133
            +PWWK NF + E V FGTWDGVFTSCM+NIFGV+IFLRTGW+VG AG+GLS+LII++T+++AL  +LS+IG+CERC + SGGVYFLLSHVLG R   ++  LY FGQAV+ SL+ +G GES++    + + W  + IG+   + +L V L GVKWV++LQLLLL IL ++VLDF++G+F     + G  GY  E    N   +F  +  FF+VFGVFFP+ATGV +GINMSGDL++P  +IP GTL+A+G  +V  LY+ FA+ LG  CT E L  D MI +KV+ +G L LFGLYVSSLS+ LG    APR+L+VI++   +P    LG+  G NK P  + + +  I + FI IGN+N L PIVT PFL+TYA++ YAYF LA S+D+           R++R+                                    D  +  N  K     +    I VD  +K   + DG      +  S  + L     +K     ++  R    +R   G         S+ +   IN EI KQP S+YS   NRW+SL G    +L+MF + W Y+L  I +  L+YIYIG   P L  G+ A+FS +  +  L   I  R   Q++ ++    IP  V+    +T+++ D+  R + HQ+
Sbjct:    1 QPWWKANFFVREPVLFGTWDGVFTSCMLNIFGVIIFLRTGWVVGNAGVGLSLLIIVITLLVALAPVLSSIGVCERCHVGSGGVYFLLSHVLGQRAGGAISLLYAFGQAVSVSLFCAGLGESLAQTAHWDSAWAVRVIGLLTALAILLVVLAGVKWVVKLQLLLLAILMLSVLDFVIGTFAHTDIAAGFTGYKTENMEKNAAPQFGAKQNFFTVFGVFFPSATGVLSGINMSGDLKDPSSNIPAGTLAALGFRWVGLLYILFAVLLGAVCTREALLTDYMIASKVSLVGVLFLFGLYVSSLSSCLGAQYGAPRVLQVISQDNVVPIIKPLGKERGANKEPYVASIFVAVIAMLFILIGNLNALAPIVTMPFLVTYASIDYAYFKLAMSYDLKQKQKLLDAGCRQQRDSETKSESSPTTKLRSDDGFSKKCIVFLLPVDATEKDDSLEKENVEKDGVPGQEKGAITVDMGSKDHGDEDGTLKPATYDDSDTTKLLGDDAEKGTKQTDKAKRQGEIKRGEQGLLFYYTKQKSYSEEQHINWEIEKQPSSYYSDLCNRWVSLAGAIASLLIMFLIHWGYALANISVTLLVYIYIGQANPSLPKGIAADFSFVRWVQSLAERITRRKPAQQQMVIPPGGIPYGVST-YQLTEDNADFAYRDRRHQS 660

[Close]

BLAST of slc12a-5 vs. Ensembl Nematostella
Match: EDO49361 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG55])

HSP 1 Score: 180.259 bits (456), Expect = 4.934e-47
Identity = 136/414 (32.85%), Postives = 224/414 (54.11%), Query Frame = 1

Query:  364 LTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV----KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEI--------------------------------LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFV 1479
            L ++ +FG   GVF  C++NI+GV+++LR  W+VG AG+GL+ +II+L+ ++  +  LS   +C   +++ GG Y+L+S  LG     S+G ++    AVA ++Y  GF E++  LL      I       + IG+  ++ +L V L G+KWV+R Q++LL +L I++LD ++G+F+      + + G +GY    F+ N    F  E  FFSVF +FFP ATG+ AG+N+SGDL+NP  ++P GTL AI VS ++Y+  A  +G T   +                                 L  DN    K +  GP++  G++ S+LS+A+  I  AP+  + + +    P   + G  +G    P    ++   I  +F  IG++N + PI++  FL+ YA ++YA FV
Sbjct:   66 LRDAPKFGWIKGVFFGCLLNIWGVMLYLRLSWVVGQAGIGLATVIIMLSAVVTTVTTLSMSAICTNGEVKGGGAYYLISRSLGPEFGGSIGIIFSIASAVAVAMYVVGFAETVRDLLKENGALIVDEVNDVRIIGLITIVFILAVALVGLKWVVRTQVILLAVLIISILDVIIGTFIGPQNASSKAQGFLGYQDGVFQTNFMPDFRGEG-FFSVFAIFFPAATGILAGVNISGDLKNPHTAVPKGTLLAILVSSLVYIVLAWLIGATYARDATGLVMSVAVVNGSSQSNVTSIPTCDTMKCLFGLYFDNQAMQKASGWGPIVTAGIFASTLSSAIASIVGAPKTFQAVCKDKLFPKIDYFGVGYGPGNEPKRGYVLAFLIACAFTAIGDLNAIAPIISNFFLIVYALINYATFV 478

[Close]

BLAST of slc12a-5 vs. Ensembl Nematostella
Match: EDO41391 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G9])

HSP 1 Score: 172.94 bits (437), Expect = 1.432e-44
Identity = 138/407 (33.91%), Postives = 224/407 (55.04%), Query Frame = 1

Query:  379 QFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIA------KXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV----KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTC----------------------TPEI---------LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            +FG   GV   C++NI+GV++FLR  W+VG +G+  S +IIIL+ ++  +  LS   +C   +++ GG Y+L+S  LG     S+G ++    AVA +LY  GF E++  +L      I       + IGV  ++ LL V L G++WV+R Q++LL IL I+++D +VGSF+    K + + G+VG + +TF  N    +     FFSVF VFFP ATG+ AG+N+SGDL++ +K+IP GTL AI +S ++Y+  A  L G C                      TP           L  D     K++  GPL+  G++ ++LS+AL  +  AP+  + + +    P   + G   G  + P    ++   I + F+ +GN+N++ P+++  FLM+YA ++YA F
Sbjct:   73 KFGWLKGVMLRCLLNIWGVMLFLRLTWVVGQSGIIWSTVIIILSALVTTVTTLSMSAVCTNGEVKGGGAYYLISRSLGPEFGGSIGLIFSLANAVAVALYVVGFAETVRDILRENGSLIIDEVNDIRVIGVISVLALLAVTLIGLEWVVRTQMVLLGILLISIVDAIVGSFIGPQDKLSVAQGIVGLNAKTFTTNLLPDYRPGEHFFSVFAVFFPAATGILAGVNISGDLKDAQKAIPKGTLWAILLSTLVYIALA-WLAGACILRDASGFVETVVNATANVTMATPPSCPGSGCLYGLINDYQAMEKMSAWGPLVTCGIFAATLSSALASLVGAPKTFQALCKDNIFPYIGYFGIGVGPGEEPRRGYILTFIIAVGFVAVGNLNVIAPVISNFFLMSYALINYAVF 478

[Close]

BLAST of slc12a-5 vs. Ensembl Nematostella
Match: EDO41917 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S304])

HSP 1 Score: 103.605 bits (257), Expect = 5.924e-23
Identity = 71/213 (33.33%), Postives = 116/213 (54.46%), Query Frame = 1

Query:  874 VKRTPSLGVVGYSIETFRNNTHARFTH--------ENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAF--LGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVL 1482
            ++++       +S +T ++N   +FT         E T+  VF + F   TG+ AG NMSGDL++P K+IP GTL+A   +FV+Y+   I  G TC+ E+L ++      +  +  L+  G++ S+LSAAL  +  A R+L  IA+  +L G         FG+N  P+ ++L+        +FIGN+N + P+V+  FL+ Y   + A FVL
Sbjct:  195 LQKSIRFSYTSWSFKTAKSNLWPKFTKDYTKDEHSEQTWLQVFAILFNGVTGIMAGANMSGDLKSPGKAIPYGTLTACLGTFVVYVILVICTGFTCSRELLVENYNYLQVIDNVRVLITIGVFASTLSAALSCLIGASRILHAIAK-DQLLGVILKPFAAGFGRNNEPLNAVLLSWFFVEIILFIGNLNTVAPLVSMFFLLCYGVTNMACFVL 406

HSP 2 Score: 53.9138 bits (128), Expect = 2.103e-7
Identity = 34/102 (33.33%), Postives = 58/102 (56.86%), Query Frame = 1

Query:  397 GVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESI 702
            GV     +++F V++FLR G++VG AGL L V + I+  +   I +LS   +     ++ GG Y+++S  LG     ++G ++ F    AS+LY  GF E++
Sbjct:    7 GVIVPVTLSMFSVILFLRLGFVVGQAGLLLGVGLFIVAYLAVSITVLSISAIATNGVVKGGGAYYMISRTLGPEFGGAIGIIFFFANVFASALYVLGFVEAL 108

[Close]

BLAST of slc12a-5 vs. Ensembl Nematostella
Match: EDO35443 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLI2])

HSP 1 Score: 73.559 bits (179), Expect = 2.071e-13
Identity = 42/133 (31.58%), Postives = 72/133 (54.14%), Query Frame = 1

Query:  928 NNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKD-------NMITAKVAFLGP-LLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLP 1302
            N    R     +FF +  +FFP+ TG+ AG N SGDL++ + SIP GT++AI  +  +Y+   +  G T   E+L+          ++ A +A+    ++L G  +S++ A +  +T AP LL+ IA+   +P
Sbjct:  223 NEGEIRSDTTTSFFILLAIFFPSVTGIMAGSNRSGDLKDAQNSIPKGTIAAIATTSFVYLTSVLLFGATIQGELLRDKFGRSIGGVLVVANIAWPTKWVILIGSLLSTIGAGMQSLTGAPCLLQAIAKDNIIP 355

HSP 2 Score: 56.225 bits (134), Expect = 4.366e-8
Identity = 34/102 (33.33%), Postives = 55/102 (53.92%), Query Frame = 1

Query:  382 FGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASG 687
             GT  GV+   + NIFGV++F+R  W+VG AG+  +  I+ +     ++  +S   +     + +GG YF++S  LG     +VG L+  G   ASS+Y  G
Sbjct:    1 MGTIMGVYLPTIQNIFGVILFIRMSWIVGIAGVTQAFFIVFICCCCTMLTAISMSAVATNGVVPAGGSYFMISRALGPEFGGAVGLLFYLGTTFASSMYILG 102

[Close]

BLAST of slc12a-5 vs. Ensembl Medaka
Match: slc12a8 (solute carrier family 12 member 8 [Source:NCBI gene;Acc:101163861])

HSP 1 Score: 380.178 bits (975), Expect = 1.024e-120
Identity = 253/660 (38.33%), Postives = 391/660 (59.24%), Query Frame = 1

Query:  307 LFNRDPE---NKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDI-RKRREDLF--------------------KAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKE-YSSCEELDRLFP---------------ERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVID 2163
            LF+ D +      +PWW+    + E V FGTWDGVFT+CMINIFGVV+FLRTG++VG  G+ L + ++ +  ++AL+ ++S IG+CE C + SGGVY ++S VLG RV  +VG LY FGQ VA ++Y +GF ES++ LLG  N W  + +   +L+ LLG+NL GVKW++RLQLLLL +L ++ LDF++G+F    P  G +GY+    R+NT   ++    FF+VFGVFFP ATGV +G NMS DL+ P+ SIP+GTL+A+  S+ LY+ F   LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  AFLGR  G NK PV S+++   +T++F+FIG +N+L PIVT  F++TY+ + Y+YF +A +F + RK+  + F                    +  ++  QS+      ++        NS+ F+  T     +S L +E +S CEE  R                  ER +   +  T+++   P    EI     S Y+   N WI+LFG     L+MF ++W Y+L  I +  LL+ YIG  +PGL  G+A +FS  + I  + S    + ++ + E++++  +  I  +   +T+E++D+  R ++HQ+  +  D ++ 
Sbjct:   44 LFHEDAQGFQQSSQPWWRIKLFVWEPVLFGTWDGVFTTCMINIFGVVLFLRTGYLVGNTGVLLGMFLVSMVAVVALVTVMSGIGVCEHCGVGSGGVYSMISTVLGGRVGGTVGLLYVFGQCVAGAMYITGFSESVAELLGLQNQWAVRCMSAAVLLALLGINLAGVKWIVRLQLLLLAVLAVSTLDFVIGTFTHLDPEHGFIGYTPGLLRSNTVPDYSPGENFFTVFGVFFPAATGVMSGFNMSSDLQRPEHSIPVGTLAAVFTSWFLYLVFVFLLGAICTREALRYDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQERVIPSLAFLGRGKGPNKTPVASIILTSLVTMAFVFIGQVNVLAPIVTINFMLTYSFIDYSYFSVAMTFRLQRKQTRNAFSPGRRRRRRPESGAEGVLSKQEPSNKPQSRVATTKQKLMESFGLDQNSNDFSKGTEGEPCSSPLQEEAHSPCEEETRAAQQPEAKRLMEMCSGDLERSAEAHSRSTDAEGKEPHRGFEIQPMNNSIYAKLCNHWIALFGAVSSTLIMFVIQWVYALANILVAVLLFFYIGKTSPGLPKGIASQFSFFTWIKSVISGFCRKQNSPQDEIVLTPSLSGIGLKTKQLTEENVDFASRHRFHQSSFVSADHMLQ 703

[Close]

BLAST of slc12a-5 vs. Ensembl Medaka
Match: slc12a8 (solute carrier family 12 member 8 [Source:NCBI gene;Acc:101163861])

HSP 1 Score: 308.916 bits (790), Expect = 2.978e-93
Identity = 192/405 (47.41%), Postives = 282/405 (69.63%), Query Frame = 1

Query:  307 LFNRDPE---NKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRR 1512
            LF+ D +      +PWW+    + E V FGTWDGVFT+CMINIFGVV+FLRTG++VG  G+ L + ++ +  ++AL+ ++S IG+CE C + SGGVY ++S VLG RV  +VG LY FGQ VA ++Y +GF ES++ LLG  N W  + +   +L+ LLG+NL GVKW++RLQLLLL +L ++ LDF++G+F    P  G +GY+    R+NT   ++    FF+VFGVFFP ATGV +G NMS DL+ P+ SIP+GTL+A+  S+ LY+ F   LG  CT E L+ D +I  KV+ +G L L GLY+SSL++ +GG+  APR+L+ IA+   +P  AFLGR  G NK PV S+++   +T++F+FIG +N+L PIVT  F++TY+ + Y+YF +A +F +++++
Sbjct:   44 LFHEDAQGFQQSSQPWWRIKLFVWEPVLFGTWDGVFTTCMINIFGVVLFLRTGYLVGNTGVLLGMFLVSMVAVVALVTVMSGIGVCEHCGVGSGGVYSMISTVLGGRVGGTVGLLYVFGQCVAGAMYITGFSESVAELLGLQNQWAVRCMSAAVLLALLGINLAGVKWIVRLQLLLLAVLAVSTLDFVIGTFTHLDPEHGFIGYTPGLLRSNTVPDYSPGENFFTVFGVFFPAATGVMSGFNMSSDLQRPEHSIPVGTLAAVFTSWFLYLVFVFLLGAICTREALRYDFLIAEKVSLVGFLFLLGLYISSLASCMGGLYGAPRILQCIAQERVIPSLAFLGRGKGPNKTPVASIILTSLVTMAFVFIGQVNVLAPIVTINFMLTYSFIDYSYFSVAMTFRLQRKQ 448

HSP 2 Score: 90.1225 bits (222), Expect = 3.977e-18
Identity = 59/218 (27.06%), Postives = 105/218 (48.17%), Query Frame = 1

Query: 1561 KVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKE-YSSCEELDRLFP---------------ERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVA-EFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVID 2163
            K+    G+D     NS+ F+  T     +S L +E +S CEE  R                  ER +   +  T+++   P    EI     S Y+   N WI+LFG     L+MF ++W Y+L  I +  LL+ YIG  +PGL  G+A +FS  + I  + S    + ++ + E++++  +  I  +   +T+E++D+  R ++HQ+  +  D ++ 
Sbjct:  532 KLMESFGLD----QNSNDFSKGTEGEPCSSPLQEEAHSPCEEETRAAQQPEAKRLMEMCSGDLERSAEAHSRSTDAEGKEPHRGFEIQPMNNSIYAKLCNHWIALFGAVSSTLIMFVIQWVYALANILVAVLLFFYIGKTSPGLPKGIASQFSFFTWIKSVISGFCRKQNSPQDEIVLTPSLSGIGLKTKQLTEENVDFASRHRFHQSSFVSADHMLQ 745

[Close]

BLAST of slc12a-5 vs. Ensembl Medaka
Match: ENSORLT00000021359.2 (solute carrier family 12 member 2 [Source:NCBI gene;Acc:101171840])

HSP 1 Score: 152.91 bits (385), Expect = 1.005e-37
Identity = 129/412 (31.31%), Postives = 221/412 (53.64%), Query Frame = 1

Query:  376 VQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWI------AKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFV---KRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGT------------------CTPEI------------------LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            V+FG   GV   CM+NI+GV++F+R  W+VG AG+GL++ II++  ++  I  LS   +     +  GG Y+L+S  LG     S+G ++ F  AVA ++Y  GF E++  +L   +  +       + +G   +I+LLG+++ G++W  + Q++LL+IL  A+ +F +G+ +    + P  G  GY       N    F  E TFFSVF +FFP ATG+ AG N+SGDL +P+ +IP GTL AI ++ + Y+  AI+ G T                  CT                     L  D  + + V+   PL+  G++ ++LS+AL  + +AP++ + + +    PG +   + +GKN  P+   ++   I ++FI I  +N++ PI++  FL +YA ++++ F
Sbjct:  186 VKFGWVKGVLVRCMLNIWGVMLFIRMSWIVGQAGIGLTIAIILMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVEMLNDVDALMFDELNDIRIVGTLTVILLLGISVAGMEWEAKAQIVLLVILLGAIANFFIGTVMPSENKKPK-GYFGYQTAILVENFGPDFRDEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITGLTYVAVAISTGATIVRDATGDHNDTVVDTVNCTDAACTLGYDFSICEEGGCKYGLMNDFQVMSLVSAFSPLISAGIFSATLSSALASLVSAPKVFQALCKDNIYPGLSVFAKGYGKNNEPLRGYVLTFCIGLAFILIAELNVIAPIISNFFLASYALINFSVF 596

[Close]

BLAST of slc12a-5 vs. Ensembl Medaka
Match: slc12a1 (solute carrier family 12 member 1 [Source:NCBI gene;Acc:101173045])

HSP 1 Score: 147.902 bits (372), Expect = 3.645e-36
Identity = 131/416 (31.49%), Postives = 223/416 (53.61%), Query Frame = 1

Query:  373 SVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWI------AKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGT-----------------------------------CTPEI----LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            +++FG   GV   CM+NI+GV++F+R  W+ G AG GL +++I+L+ ++  I  LS   +C    +  GG Y+L+S  LG     S+G ++ F  AVA ++Y  GF E++  LL   N  +       + +G   +++LLG+++ G++W  + Q+LLL+IL +A+++  VG+ +  T    S G   Y  + F  N    F +  TFFSVF +FFP ATG+ AG N+SGDLR+P+ +IP GTL AI ++ V Y+  A+ +  T                                   C  E     L  +  +   V+  GPL++ G + ++LS+AL  + +AP++ + + +        F  +  GKN  P+   ++   I+++FI IGN+N + PI++  FL +YA ++++ F
Sbjct:  122 AIRFGWIRGVLVRCMLNIWGVMLFIRLSWVFGQAGWGLGIVVILLSCVVTTITGLSMSAICTNGVVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVDLLIEHNAIMIDPINDIRIVGCITVVLLLGISVAGMEWEAKAQILLLVILLVAIVNVFVGTAIPATEDKKSKGFFSYQSKIFLENFTPDFRNGETFFSVFAIFFPAATGILAGANISGDLRDPQAAIPKGTLLAILITGVTYLGVALCVSATVVRDATGNRNNSVPLGTVCNGSSAIACDFGYDFSSCEVESCKFGLMNNFQVMTMVSGFGPLIIAGTFSATLSSALASLVSAPKVFQALCKDNIYRALHFFAKGHGKNNEPIRGYVLTFIISVAFILIGNLNTIAPIISNFFLASYALINFSCF 537

[Close]

BLAST of slc12a-5 vs. Ensembl Medaka
Match: slc12a1 (solute carrier family 12 member 1 [Source:NCBI gene;Acc:101173045])

HSP 1 Score: 147.902 bits (372), Expect = 3.884e-36
Identity = 131/416 (31.49%), Postives = 223/416 (53.61%), Query Frame = 1

Query:  373 SVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWI------AKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTP---SLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGT-----------------------------------CTPEI----LQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYF 1476
            +++FG   GV   CM+NI+GV++F+R  W+ G AG GL +++I+L+ ++  I  LS   +C    +  GG Y+L+S  LG     S+G ++ F  AVA ++Y  GF E++  LL   N  +       + +G   +++LLG+++ G++W  + Q+LLL+IL +A+++  VG+ +  T    S G   Y  + F  N    F +  TFFSVF +FFP ATG+ AG N+SGDLR+P+ +IP GTL AI ++ V Y+  A+ +  T                                   C  E     L  +  +   V+  GPL++ G + ++LS+AL  + +AP++ + + +        F  +  GKN  P+   ++   I+++FI IGN+N + PI++  FL +YA ++++ F
Sbjct:  122 AIRFGWIRGVLVRCMLNIWGVMLFIRLSWVFGQAGWGLGIVVILLSCVVTTITGLSMSAICTNGVVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVDLLIEHNAIMIDPINDIRIVGCITVVLLLGISVAGMEWEAKAQILLLVILLVAIVNVFVGTAIPATEDKKSKGFFSYQSKIFLENFTPDFRNGETFFSVFAIFFPAATGILAGANISGDLRDPQAAIPKGTLLAILITGVTYLGVALCVSATVVRDATGNRNNSVPLGTVCNGSSAIACDFGYDFSSCEVESCKFGLMNNFQVMTMVSGFGPLIIAGTFSATLSSALASLVSAPKVFQALCKDNIYRALHFFAKGHGKNNEPIRGYVLTFIISVAFILIGNLNTIAPIISNFFLASYALINFSCF 537

[Close]

BLAST of slc12a-5 vs. Planmine SMEST
Match: SMESG000017210.1 (SMESG000017210.1)

HSP 1 Score: 1111.29 bits (2873), Expect = 0.000e+0
Identity = 666/668 (99.70%), Postives = 668/668 (100.00%), Query Frame = 1

Query:  187 MKNSDGSQDANWSKFGLXXXXXXXXXXXXXXXXXXXXXXXLFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKXXXXXXXXXXXXXXXXXXKWVIRXXXXXXXXXXXXXXXXXXGSFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDALAGVGNNK 2190
            MKNSDGSQDANWSKFGLTKSRTTTKSESEEYKEEDAKENELFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVLIIILTMIIALIAILSAIGLCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKGIGVGILIILLGVNLTGVKWVIRLQLLLLLILFIAVLDFLVGSFVKR+PSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPV+SLLIIVSITISFIFIGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDALAGVGNNK
Sbjct:    1 MKNSDGSQDANWSKFGLTKSRTTTKSESEEYKEEDAKENELFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVLIIILTMIIALIAILSAIGLCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKGIGVGILIILLGVNLTGVKWVIRLQLLLLLILFIAVLDFLVGSFVKRSPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPVYSLLIIVSITISFIFIGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDALAGVGNNK 668

[Close]

BLAST of slc12a-5 vs. Planmine SMEST
Match: SMESG000017210.1 (SMESG000017210.1)

HSP 1 Score: 825.854 bits (2132), Expect = 0.000e+0
Identity = 434/441 (98.41%), Postives = 438/441 (99.32%), Query Frame = 1

Query:  868 SFVKRTPSLGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDALAGVGNNK 2190
            +FV +  +LGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPV+SLLIIVSITISFIFIGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDALAGVGNNK
Sbjct:  217 TFVTKQKALGVVGYSIETFRNNTHARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPVYSLLIIVSITISFIFIGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAINHSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEELDRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGTFMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCISHLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQKMDKDRVIDALAGVGNNK 657

HSP 2 Score: 249.98 bits (637), Expect = 1.733e-72
Identity = 167/167 (100.00%), Postives = 167/167 (100.00%), Query Frame = 1

Query:  187 MKNSDGSQDANWSKFGLXXXXXXXXXXXXXXXXXXXXXXXLFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASG 687
            MKNSDGSQDANWSKFGLTKSRTTTKSESEEYKEEDAKENELFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVLIIILTMIIALIAILSAIGLCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASG
Sbjct:    1 MKNSDGSQDANWSKFGLTKSRTTTKSESEEYKEEDAKENELFNRDPENKKKPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVLIIILTMIIALIAILSAIGLCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASG 167

HSP 3 Score: 110.923 bits (276), Expect = 7.184e-25
Identity = 55/85 (64.71%), Postives = 61/85 (71.76%), Query Frame = 3

Query:  639 FILFWTGGS*LPIRVWFWRKYFKSIRIYKPLDSERNRSWYFNNSLRSKPHRREMGDSPSAPSFTYFIHSSIGLPGGFICQTDTFA 893
            F+L    GS +   V F   + +++        ERNRSWYFNNSLRSKPHRREMGDSPSAPSFTYFIHSSIGLPGG ICQT TF 
Sbjct:  135 FLLSHVLGSRVATSVGFLYCFGQAVASSLYASGERNRSWYFNNSLRSKPHRREMGDSPSAPSFTYFIHSSIGLPGGLICQTVTFV 219

[Close]

BLAST of slc12a-5 vs. Planmine SMEST
Match: SMESG000033021.1 (SMESG000033021.1)

HSP 1 Score: 91.2781 bits (225), Expect = 1.464e-18
Identity = 61/195 (31.28%), Postives = 100/195 (51.28%), Query Frame = 1

Query:  904 GYSIETFRNNTHARFTHE------NTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYA 1470
            G S  TF NN +A +T +       TFF+VF + FP  TG+  G NMSG+L  P  SIP GTL+A   +F+ Y+        TC   +L  + +         P ++ G++++ +SAALG    A R+L  +A+           +   K   P+ S++I   +    + IG +N++ P+V+  FL+ YA+++ A
Sbjct:  247 GLSGTTFINNLYANYTVDFTTKKYMTFFTVFAILFPGVTGIMNGANMSGELIKPAVSIPRGTLAATLFTFICYIISFFLSAATCDRFLLWNNYLFMQATNLWKPFVIIGMFLTCISAALGNFIGASRILFALAQDDIFGIFLKPAKLTTKGGNPIGSVVISFVLVQIVLLIGKVNVIAPVVSVFFLLAYASVNLA 441

HSP 2 Score: 52.373 bits (124), Expect = 1.422e-6
Identity = 37/110 (33.64%), Postives = 62/110 (56.36%), Query Frame = 1

Query:  388 TWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLG 717
            T+ GVF    +  F  ++FLR G+++G  GL L++L +I+  +I L+ +LS   +     I+ GGVYF++S  LG  V  S+G L+      +S+L+ + F E +    G
Sbjct:   46 TFTGVFCPVALAQFSSLLFLRLGFVLGQTGLLLAILQLIMAYLILLLTVLSICAISTNGAIKGGGVYFMISRTLGPEVGGSIGILFFLANVFSSALFMAAFVEGLVDDFG 155

[Close]

BLAST of slc12a-5 vs. Planmine SMEST
Match: SMESG000060496.1 (SMESG000060496.1)

HSP 1 Score: 84.7297 bits (208), Expect = 1.488e-16
Identity = 55/177 (31.07%), Postives = 93/177 (52.54%), Query Frame = 1

Query:  952 HENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVL 1482
            ++  F SVF + F   TG+  G NMSG+L+ P  SIP GTL+A   +F+ Y    +    TC   +L  + +    + F  P +L G+  + LSA LG +  A R+L  +A+           +   K   P+ S++I   +    +FIG +N++ P+V+  FL+ YA++++A  +L
Sbjct:  265 NQMDFLSVFAIMFSGVTGIMNGANMSGELKQPAISIPKGTLAAALFTFICYTLSFLLSAATCERFLLLNNYLYMQAINFWRPFVLIGIIATCLSAGLGNLIGASRILYALAKDDIFGFLLKPAKLATKGGNPIASVVISFVLVQLVLFIGQLNLIAPVVSVFFLLAYASVNFACALL 441

HSP 2 Score: 54.299 bits (129), Expect = 3.799e-7
Identity = 41/143 (28.67%), Postives = 72/143 (50.35%), Query Frame = 1

Query:  310 FNRDPENKKKPWWKTNF--LLTESVQ-----FGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLG 717
             + + E  K+ ++       LT SV        T+ GVF    +  F  ++FLR G ++G  GL ++++ +++  +I ++ +LS   +     +E GGVYF++S  LG  V  S+G L+      +S+LY SG  E +    G
Sbjct:    7 LHDESEQNKRHYYDLTISETLTASVDQSKRTLKTFTGVFCPVALAQFSSLLFLRLGCVLGQTGLVIALVQLVMAYVILVLTVLSICAISTNGAVEGGGVYFMISRTLGPEVGGSIGILFFLANVFSSALYMSGLVEGLMDDFG 149

[Close]

BLAST of slc12a-5 vs. Planmine SMEST
Match: SMESG000060496.1 (SMESG000060496.1)

HSP 1 Score: 84.7297 bits (208), Expect = 1.518e-16
Identity = 55/177 (31.07%), Postives = 93/177 (52.54%), Query Frame = 1

Query:  952 HENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIGVSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSAALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPXXXXXXXXXXXXXXXXXGNINILGPIVTTPFLMTYATLSYAYFVL 1482
            ++  F SVF + F   TG+  G NMSG+L+ P  SIP GTL+A   +F+ Y    +    TC   +L  + +    + F  P +L G+  + LSA LG +  A R+L  +A+           +   K   P+ S++I   +    +FIG +N++ P+V+  FL+ YA++++A  +L
Sbjct:  270 NQMDFLSVFAIMFSGVTGIMNGANMSGELKQPAISIPKGTLAAALFTFICYTLSFLLSAATCERFLLLNNYLYMQAINFWRPFVLIGIIATCLSAGLGNLIGASRILYALAKDDIFGFLLKPAKLATKGGNPIASVVISFVLVQLVLFIGQLNLIAPVVSVFFLLAYASVNFACALL 446

HSP 2 Score: 54.299 bits (129), Expect = 3.969e-7
Identity = 41/143 (28.67%), Postives = 72/143 (50.35%), Query Frame = 1

Query:  310 FNRDPENKKKPWWKTNF--LLTESVQ-----FGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGLSVXXXXXXXXXXXXXXXXXXXXCERCKIESGGVYFLLSHVLGSRVATSVGFLYCFGQAVASSLYASGFGESISSLLG 717
             + + E  K+ ++       LT SV        T+ GVF    +  F  ++FLR G ++G  GL ++++ +++  +I ++ +LS   +     +E GGVYF++S  LG  V  S+G L+      +S+LY SG  E +    G
Sbjct:   12 LHDESEQNKRHYYDLTISETLTASVDQSKRTLKTFTGVFCPVALAQFSSLLFLRLGCVLGQTGLVIALVQLVMAYVILVLTVLSICAISTNGAVEGGGVYFMISRTLGPEVGGSIGILFFLANVFSSALYMSGLVEGLMDDFG 154

The following BLAST results are available for this feature:

BLAST of slc12a-5 vs. Ensembl Human
BLAST of slc12a-5 vs. Ensembl Celegans
BLAST of slc12a-5 vs. Ensembl Fly
BLAST of slc12a-5 vs. Ensembl Zebrafish
BLAST of slc12a-5 vs. Ensembl Xenopus
BLAST of slc12a-5 vs. Ensembl Mouse
BLAST of slc12a-5 vs. UniProt/SwissProt
BLAST of slc12a-5 vs. TrEMBL
BLAST of slc12a-5 vs. Ensembl Cavefish
BLAST of slc12a-5 vs. Ensembl Sea Lamprey
BLAST of slc12a-5 vs. Ensembl Yeast
BLAST of slc12a-5 vs. Ensembl Nematostella
BLAST of slc12a-5 vs. Ensembl Medaka
BLAST of slc12a-5 vs. Planmine SMEST

BLAST of slc12a-5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SLC12A8	4.147e-95	44.02	solute carrier family 12 member 8 [Source:HGNC Sym...	[more]
SLC12A8	4.147e-95	44.02	solute carrier family 12 member 8 [Source:HGNC Sym...	[more]
SLC12A2	9.889e-38	32.38	solute carrier family 12 member 2 [Source:HGNC Sym...	[more]
SLC12A2	1.144e-37	32.38	solute carrier family 12 member 2 [Source:HGNC Sym...	[more]
SLC12A2	1.382e-37	32.38	solute carrier family 12 member 2 [Source:HGNC Sym...	[more]

BLAST of slc12a-5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
F10E7.9	3.156e-95	35.62	pep chromosome:WBcel235:II:7106412:7110056:-1 gene...	[more]
nkcc-1	5.686e-49	33.50	Na-K-Cl Cotransporter homolog [Source:UniProtKB/T...	[more]
nkcc-1	8.524e-49	33.50	Na-K-Cl Cotransporter homolog [Source:UniProtKB/T...	[more]
nkcc-1	1.000e-48	33.50	Na-K-Cl Cotransporter homolog [Source:UniProtKB/T...	[more]
nkcc-1	1.022e-48	33.50	Na-K-Cl Cotransporter homolog [Source:UniProtKB/T...	[more]

BLAST of slc12a-5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG12773	9.171e-124	40.06	gene:FBgn0024365 transcript:FBtr0342738	[more]
CG12773	9.171e-124	40.06	gene:FBgn0024365 transcript:FBtr0070235	[more]
CG12773	2.819e-120	39.91	gene:FBgn0024365 transcript:FBtr0332287	[more]
Ncc69	1.083e-38	31.16	gene:FBgn0036279 transcript:FBtr0333840	[more]
Ncc69	1.157e-38	31.16	gene:FBgn0036279 transcript:FBtr0333842	[more]

BLAST of slc12a-5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc12a8	6.156e-94	36.90	solute carrier family 12 member 8 [Source:ZFIN;Acc...	[more]
slc12a8	7.070e-46	51.63	solute carrier family 12 member 8 [Source:ZFIN;Acc...	[more]
slc12a10.3	1.011e-35	30.17	solute carrier family 12 member 10, tandem duplica...	[more]
slc12a10.3	1.207e-35	30.17	solute carrier family 12 member 10, tandem duplica...	[more]
slc12a10.1	1.550e-35	29.76	solute carrier family 12 member 10, tandem duplica...	[more]

BLAST of slc12a-5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SLC12A2	8.300e-38	31.98	solute carrier family 12 member 2 [Source:NCBI gen...	[more]
SLC12A2	9.085e-38	31.98	solute carrier family 12 member 2 [Source:NCBI gen...	[more]
SLC12A2	9.758e-38	31.98	solute carrier family 12 member 2 [Source:NCBI gen...	[more]
SLC12A2	1.023e-37	31.98	solute carrier family 12 member 2 [Source:NCBI gen...	[more]
SLC12A2	1.040e-37	31.98	solute carrier family 12 member 2 [Source:NCBI gen...	[more]

BLAST of slc12a-5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Slc12a8	1.490e-108	38.70	solute carrier family 12 (potassium/chloride trans...	[more]
Slc12a8	1.490e-108	38.70	solute carrier family 12 (potassium/chloride trans...	[more]
Slc12a8	3.586e-87	38.99	solute carrier family 12 (potassium/chloride trans...	[more]
Slc12a8	7.139e-84	35.60	solute carrier family 12 (potassium/chloride trans...	[more]
Slc12a8	2.397e-47	30.89	solute carrier family 12 (potassium/chloride trans...	[more]

BLAST of slc12a-5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6A4L1\|S12A8_XENLA	1.544e-121	39.08	Solute carrier family 12 member 8 OS=Xenopus laevi...	[more]
sp\|Q8VI23\|S12A8_MOUSE	1.042e-107	38.70	Solute carrier family 12 member 8 OS=Mus musculus ...	[more]
sp\|A0AV02\|S12A8_HUMAN	1.991e-94	44.02	Solute carrier family 12 member 8 OS=Homo sapiens ...	[more]
sp\|Q8CJI3\|S12A8_RAT	1.551e-93	37.05	Solute carrier family 12 member 8 OS=Rattus norveg...	[more]
sp\|P55012\|S12A2_MOUSE	7.886e-38	32.62	Solute carrier family 12 member 2 OS=Mus musculus ...	[more]

BLAST of slc12a-5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0H3YJ24	0.000e+0	100.00	Slc12a-5 OS=Schmidtea mediterranea OX=79327 GN=slc...	[more]
A0A1S3K6X4	3.573e-150	46.48	solute carrier family 12 member 8 isoform X2 OS=Li...	[more]
A0A1S3K5V4	3.740e-150	46.48	solute carrier family 12 member 8 isoform X1 OS=Li...	[more]
A0A2C9K4Y5	1.003e-143	43.73	AA_permease domain-containing protein OS=Biomphala...	[more]
V4A5Y4	1.152e-142	44.57	AA_permease domain-containing protein (Fragment) O...	[more]

BLAST of slc12a-5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc12a8	6.542e-103	39.13	solute carrier family 12 member 8 [Source:NCBI gen...	[more]
slc12a8	8.573e-92	47.52	solute carrier family 12 member 8 [Source:NCBI gen...	[more]
slc12a8	1.620e-71	42.33	solute carrier family 12 member 8 [Source:NCBI gen...	[more]
SLC12A2	2.605e-39	31.64	solute carrier family 12 member 2-like [Source:NCB...	[more]
slc12a1	3.937e-36	29.78	solute carrier family 12 member 1 [Source:ZFIN;Acc...	[more]

BLAST of slc12a-5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc12a8	4.296e-116	39.70	solute carrier family 12 member 8 [Source:ZFIN;Acc...	[more]
ENSPMAT00000003053.1	3.337e-33	29.69	pep scaffold:Pmarinus_7.0:GL478333:5880:33924:-1 g...	[more]
slc12a9	3.143e-19	29.70	solute carrier family 12 member 9 [Source:NCBI gen...	[more]
ENSPMAT00000001762.1	1.328e-16	42.86	pep scaffold:Pmarinus_7.0:GL484736:821:6283:1 gene...	[more]
slc12a4	9.460e-10	33.33	solute carrier family 12 member 4 [Source:ZFIN;Acc...	[more]

BLAST of slc12a-5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
VHC1	7.131e-21	25.36	Vacuolar membrane cation-chloride cotransporter (C...	[more]

BLAST of slc12a-5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46430	8.938e-130	41.45	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49361	4.934e-47	32.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41391	1.432e-44	33.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41917	5.924e-23	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35443	2.071e-13	31.58	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of slc12a-5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slc12a8	1.024e-120	38.33	solute carrier family 12 member 8 [Source:NCBI gen...	[more]
slc12a8	2.978e-93	47.41	solute carrier family 12 member 8 [Source:NCBI gen...	[more]
ENSORLT00000021359.2	1.005e-37	31.31	solute carrier family 12 member 2 [Source:NCBI gen...	[more]
slc12a1	3.645e-36	31.49	solute carrier family 12 member 1 [Source:NCBI gen...	[more]
slc12a1	3.884e-36	31.49	solute carrier family 12 member 1 [Source:NCBI gen...	[more]

BLAST of slc12a-5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000017210.1	0.000e+0	99.70	SMESG000017210.1	[more]
SMESG000017210.1	1.733e-72	98.41	SMESG000017210.1	[more]
SMESG000033021.1	1.464e-18	31.28	SMESG000033021.1	[more]
SMESG000060496.1	1.488e-16	31.07	SMESG000060496.1	[more]
SMESG000060496.1	1.518e-16	31.07	SMESG000060496.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30021618
GenBank	AKN21479.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30021618 ID=SMED30021618|Name=slc12a-5|organism=Schmidtea mediterranea sexual|type=transcript|length=2368bp
CCAATCACAATCAATTATAGTTATTGATTATTTAATATTGTTATTTAATC
GTGTAAAATAAATTTGAATAAATTTAAATTGAATAATATTCCTGTAGAAA
TTCTAAATTTGTTTTGTTAGTTGATTGAGGAATTATTTAGAGTGGAATTG
TTAATTGTTTCATTGTCTCAGTTCCAACAGTGGTAAATGAAAAATTCAGA
TGGATCTCAGGACGCGAACTGGTCGAAATTTGGGTTGACGAAATCGCGGA
CGACAACAAAAAGTGAATCCGAGGAATACAAGGAAGAGGATGCAAAAGAA
AATGAATTGTTCAATAGAGATCCCGAAAATAAAAAGAAACCTTGGTGGAA
AACAAATTTTTTATTGACAGAATCTGTGCAATTTGGAACCTGGGACGGTG
TCTTTACATCTTGCATGATCAATATCTTTGGCGTTGTCATTTTCCTGAGA
ACCGGATGGATGGTGGGTTTTGCAGGTTTAGGTTTGTCAGTTTTGATAAT
CATCCTGACCATGATCATTGCCTTGATCGCCATTTTGAGTGCTATAGGAC
TCTGTGAACGATGCAAAATTGAATCAGGAGGAGTTTACTTTTTGCTGTCC
CATGTCCTTGGTTCACGCGTAGCCACATCAGTTGGATTTTTATATTGTTT
TGGACAGGCGGTAGCTAGCTCCCTATACGCGTCTGGTTTTGGAGAAAGTA
TTTCAAGTCTATTAGGATATACAAACCCTTGGATAGCGAAAGGAATAGGA
GTTGGTATTTTAATAATTCTCTTAGGAGTAAACCTCACCGGCGTGAAATG
GGTGATTCGCCTTCAGCTCCTTCTTTTACTTATTTTATTCATAGCAGTAT
TGGACTTCCTGGTGGGTTCATTTGTCAAACGGACACCTTCGCTTGGTGTT
GTCGGTTACAGCATCGAAACTTTTAGAAACAATACGCATGCACGATTTAC
GCATGAAAATACTTTTTTTTCCGTTTTTGGAGTGTTTTTCCCAACAGCTA
CAGGAGTTTGTGCAGGCATTAATATGAGCGGGGACCTGAGAAATCCCAAA
AAGTCAATTCCTCTCGGTACATTATCAGCAATAGGGGTCAGTTTTGTGCT
TTATATGTGCTTTGCAATTGCATTAGGCGGAACATGCACCCCGGAAATTC
TTCAAAAAGATAACATGATCACAGCCAAAGTTGCGTTTCTTGGGCCTCTT
TTACTTTTTGGCCTTTACGTGTCTTCACTCAGTGCGGCACTCGGAGGAAT
TACTACTGCTCCAAGATTGTTAAAAGTTATTGCAGAAACTACCAAACTTC
CTGGAACTGCATTTTTAGGAAGACATTTTGGAAAGAACAAAGTTCCCGTA
TTTTCCTTGCTAATTATAGTGTCAATAACAATTTCTTTCATATTTATTGG
GAACATCAACATATTGGGCCCAATCGTCACCACCCCCTTTCTCATGACAT
ATGCTACTCTATCATACGCTTATTTTGTCCTTGCTAAATCGTTTGATATC
AGAAAACGCCGGGAGGACTTATTTAAGGCCATCAATCATTCAAAACAGTC
AAAAGGTGTCAAAGTGTCCCATCAAATTGGAGTGGATACCAAAAGTGGTT
CCAATTCTGATGGATTTACACATTCCACGGGTTCAAATTTAGAAAACTCT
TCTCTGGATAAGGAATACAGCTCGTGTGAAGAATTGGATCGACTATTTCC
AGAAAGAATTTCGTATGGAGCTACTGCTGAAACTAATTCCGACAATTCAT
TCCCGAAAATCAACAAAGAAATAATTAAACAGCCGAGATCCTTCTATTCC
ATATTCATCAACAGGTGGATCTCCTTGTTTGGAACCTTCATGTTCATCCT
GTTGATGTTCGGGGTGGAATGGACCTACTCGTTGATAGGGATAGGCATAT
GGTTTCTCCTTTACATCTACATCGGATATGTAACTCCGGGTTTGTTTCCC
GGCGTTGCTGAATTCTCTATCTTATCCTGTATTTCTCACCTTCCCTCTGC
AATCAGATCCAGAAATTCCAATCAAGAAAGAGAAATGTTGATATCGAAGA
AGATTCCCGAGATTGTCACCGAGCCGATCTGTGTTACCGACGAATCGCTG
GACTACATCGACAGAGGTAAATATCACCAAGCTCAAAAAATGGACAAGGA
CAGAGTTATCGATGCTCTGGCGGGGGTCGGCAATAACAAATGAAAGATTT
TATGGGAAATGTAGCTTAATAATTTATATGCAGATTTGTTACTAGAACGG
CTGTGATAATCTCTATAGTTTCTGTTACACAGCGTGGAGCCGTGGGCCAC
ACGGATTTATTGCCTTGAGGCTATTATTGCATATGACTTTTTGTGAAATA
TATTTACAGGATTTCAAA

protein sequence of SMED30021618-orf-1

>SMED30021618-orf-1 ID=SMED30021618-orf-1|Name=SMED30021618-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=669bp
MKNSDGSQDANWSKFGLTKSRTTTKSESEEYKEEDAKENELFNRDPENKK
KPWWKTNFLLTESVQFGTWDGVFTSCMINIFGVVIFLRTGWMVGFAGLGL
SVLIIILTMIIALIAILSAIGLCERCKIESGGVYFLLSHVLGSRVATSVG
FLYCFGQAVASSLYASGFGESISSLLGYTNPWIAKGIGVGILIILLGVNL
TGVKWVIRLQLLLLLILFIAVLDFLVGSFVKRTPSLGVVGYSIETFRNNT
HARFTHENTFFSVFGVFFPTATGVCAGINMSGDLRNPKKSIPLGTLSAIG
VSFVLYMCFAIALGGTCTPEILQKDNMITAKVAFLGPLLLFGLYVSSLSA
ALGGITTAPRLLKVIAETTKLPGTAFLGRHFGKNKVPVFSLLIIVSITIS
FIFIGNINILGPIVTTPFLMTYATLSYAYFVLAKSFDIRKRREDLFKAIN
HSKQSKGVKVSHQIGVDTKSGSNSDGFTHSTGSNLENSSLDKEYSSCEEL
DRLFPERISYGATAETNSDNSFPKINKEIIKQPRSFYSIFINRWISLFGT
FMFILLMFGVEWTYSLIGIGIWFLLYIYIGYVTPGLFPGVAEFSILSCIS
HLPSAIRSRNSNQEREMLISKKIPEIVTEPICVTDESLDYIDRGKYHQAQ
KMDKDRVIDALAGVGNNK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR004841	AA-permease/SLC12A_dom

Vocabulary: **biological process**
Term	Definition
GO:0055085	transmembrane transport
GO:0006810	transport

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR004841	Amino acid permease/ SLC12A domain	PFAM	PF00324	AA_permease	coord: 72..447 e-value: 8.3E-46 score: 156.6
None	No IPR available	GENE3D	G3DSA:1.20.1740.10		coord: 62..450 e-value: 9.8E-36 score: 125.4
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..22
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..42
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 23..42
None	No IPR available	PANTHER	PTHR11827	SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS	coord: 8..487
None	No IPR available	PANTHER	PTHR11827:SF6	SOLUTE CARRIER FAMILY 12 MEMBER 8	coord: 488..654
None	No IPR available	PANTHER	PTHR11827:SF6	SOLUTE CARRIER FAMILY 12 MEMBER 8	coord: 8..487
None	No IPR available	PANTHER	PTHR11827	SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS	coord: 488..654
None	No IPR available	TMHMM	TMhelix		coord: 386..405
None	No IPR available	TMHMM	TMhelix		coord: 568..590
None	No IPR available	TMHMM	TMhelix		coord: 536..558
None	No IPR available	TMHMM	TMhelix		coord: 134..156
None	No IPR available	TMHMM	TMhelix		coord: 291..313
None	No IPR available	TMHMM	TMhelix		coord: 71..90
None	No IPR available	TMHMM	TMhelix		coord: 259..278
None	No IPR available	TMHMM	TMhelix		coord: 409..431
None	No IPR available	TMHMM	TMhelix		coord: 176..198
None	No IPR available	TMHMM	TMhelix		coord: 333..355
None	No IPR available	TMHMM	TMhelix		coord: 100..122
None	No IPR available	TMHMM	TMhelix		coord: 205..227