Neuronal acetylcholine receptor subunit alpha-2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30021617 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Human
Match: CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit [Source:HGNC Symbol;Acc:HGNC:14079]) HSP 1 Score: 211.46 bits (537), Expect = 2.069e-59 Identity = 127/340 (37.35%), Postives = 195/340 (57.35%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLG 1419
L N+L Y RPV E + VT++ LS QI +DE +QILT+ + W D ++ W YD + + IP+ +W PDI +YN AD+ E + +++YDG + W AI KS+C V + YFPFD Q C L FG WTY+G +++I ++ D ++++ +VEWE+ A + Y CC EPYPD++F +L++R S+FY L++PC L+S L + F+LPA S K+ LG+ I +A + +++ + +P AS + PLIG YY M LIT ST L ++ +N HF G + VP W + + +K+ +R+LFV D+G
Sbjct: 34 LFNDLFEDYSNALRPV-------------EDTDKVLNVTLQITLS--QIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDI--FNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMP-ASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWARVVILKYMSRVLFVYDVG 355
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Human
Match: CHRNA10 (cholinergic receptor nicotinic alpha 10 subunit [Source:HGNC Symbol;Acc:HGNC:13800]) HSP 1 Score: 205.682 bits (522), Expect = 1.377e-57 Identity = 124/336 (36.90%), Postives = 189/336 (56.25%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
L +L Y RPV D +Q++ VT+E LS QI+ +DE +Q+LT + W D ++RW P+ Y + + IP+ +W PDI +YN AD + + ++++DG V W AI +S+C V + FPFD Q C L FG WT+ G +L++ L ++V NVEW ++ A+ + Y CC EPYPD++F +L++R +A Y L+LPC L+S L + F LPA+S K+ LG+ + +A + +LL +S+P A S PLIG YY MT++T ST L ++ +N H+ G + + VP W + L + H AR L V
Sbjct: 33 LFRDLFANYTSALRPVADT------------DQTLN-VTLEVTLS--QIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASL--ADFVENVEWRVLGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAFHLPADSGEKVSLGVTVLLALTVFQLLLAESMPPA-ESVPLIGKYYMATMTMVTFSTALTILIMNLHYCGPSVRPVPAWARALLLGHLARGLCV 350
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Human
Match: CHRNA4 (cholinergic receptor nicotinic alpha 4 subunit [Source:HGNC Symbol;Acc:HGNC:1958]) HSP 1 Score: 207.608 bits (527), Expect = 1.151e-56 Identity = 120/350 (34.29%), Postives = 206/350 (58.86%), Query Frame = 1
Query: 382 KSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILK 1431
++ E+ L+ +L +GY+K SRPV N++ V V V FGLS+ Q++ +DE +Q++T+NV W DY +RW P Y+N+T + IP++ +W PDI +YN AD A + +DG V+W P AI+KS+C + + +FPFD+Q C +KFG WTYD ++++ + + +DQ ++ + EW ++ + T +Y CC E YPDI++ +++R FY LI+PC L+S LT+++F+LP+E K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R +P W++++ + R+L + ++K
Sbjct: 33 RAHAEERLLKKLFSGYNKWSRPVA-NISDV--------------VLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV--NMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPTWVRRVFLDIVPRLLLMKRPSVVK 365
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Human
Match: CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956]) HSP 1 Score: 200.675 bits (509), Expect = 2.703e-55 Identity = 120/353 (33.99%), Postives = 200/353 (56.66%), Query Frame = 1
Query: 391 TEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVE 1449
TE L L GY++ +RPV NT++ V V FGLS+ Q++ +DE +Q++T+NV W DY +RW P + NIT + +P++ +W+PDI +YN AD A + GTV W P AI+KS+C + + +FPFD+Q CK+KFG WTYD ++++ + +D +Y + EW ++ + + +Y CC E YPD+++ +++R FY LI+PC L+S LT+++F+LP++ K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R + +P W++ + R L ++ + PPPVE
Sbjct: 36 TEDRLFKHLFRGYNRWARPVP---------NTSD------VVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPTDFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE--QMEQTVDLKDYWESGEWAIVNATGTYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHTMPHWVRGALLGCVPRWLLMN-----RPPPPVE 366
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Human
Match: CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:1956]) HSP 1 Score: 200.29 bits (508), Expect = 5.773e-55 Identity = 120/353 (33.99%), Postives = 200/353 (56.66%), Query Frame = 1
Query: 391 TEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVE 1449
TE L L GY++ +RPV NT++ V V FGLS+ Q++ +DE +Q++T+NV W DY +RW P + NIT + +P++ +W+PDI +YN AD A + GTV W P AI+KS+C + + +FPFD+Q CK+KFG WTYD ++++ + +D +Y + EW ++ + + +Y CC E YPD+++ +++R FY LI+PC L+S LT+++F+LP++ K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R + +P W++ + R L ++ + PPPVE
Sbjct: 58 TEDRLFKHLFRGYNRWARPVP---------NTSD------VVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPTDFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE--QMEQTVDLKDYWESGEWAIVNATGTYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHTMPHWVRGALLGCVPRWLLMN-----RPPPPVE 388
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6583461:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 222.631 bits (566), Expect = 7.081e-63 Identity = 124/337 (36.80%), Postives = 193/337 (57.27%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADER-MEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
L +LL Y+ RP V + P+ V F SL QI+ +DE +QILT+N W DY + W P LY N+T +HIP+ +W PDI +YN AD + M+ D I+ Y G + W AIF S+CP+ +K++PFDRQ C LK+ W YDG ++++ + +L NY+ N EW LI RA+ V Y CC EPYP I H+ ++R + FY + LILPC L+S + L+ F++P +S K+ LG+ ++ + ++++ + +P + + PLIG Y+ + + L+ L T + + TVN H G + VP +L+ ++ ++ILFV
Sbjct: 3 LYRDLLYDYNNEVRPSVHSKEPI---------------NVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILYNNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDL--TNYITNTEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTVFTVNIHHTGVHGYPVPPFLQIFAFRYLSKILFV 322
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6583461:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 222.631 bits (566), Expect = 1.167e-62 Identity = 124/339 (36.58%), Postives = 194/339 (57.23%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADER-MEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDL 1416
L +LL Y+ RP V + P+ V F SL QI+ +DE +QILT+N W DY + W P LY N+T +HIP+ +W PDI +YN AD + M+ D I+ Y G + W AIF S+CP+ +K++PFDRQ C LK+ W YDG ++++ + +L NY+ N EW LI RA+ V Y CC EPYP I H+ ++R + FY + LILPC L+S + L+ F++P +S K+ LG+ ++ + ++++ + +P + + PLIG Y+ + + L+ L T + + TVN H G + VP +L+ ++ ++ILFV +
Sbjct: 3 LYRDLLYDYNNEVRPSVHSKEPI---------------NVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILYNNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDL--TNYITNTEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTVFTVNIHHTGVHGYPVPPFLQIFAFRYLSKILFVRI 324
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6581927:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 223.016 bits (567), Expect = 1.187e-62 Identity = 124/337 (36.80%), Postives = 193/337 (57.27%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADER-MEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
L +LL Y+ RP V + P+ V F SL QI+ +DE +QILT+N W DY + W P LY N+T +HIP+ +W PDI +YN AD + M+ D I+ Y G + W AIF S+CP+ +K++PFDRQ C LK+ W YDG ++++ + +L NY+ N EW LI RA+ V Y CC EPYP I H+ ++R + FY + LILPC L+S + L+ F++P +S K+ LG+ ++ + ++++ + +P + + PLIG Y+ + + L+ L T + + TVN H G + VP +L+ ++ ++ILFV
Sbjct: 34 LYRDLLYDYNNEVRPSVHSKEPI---------------NVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILYNNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDL--TNYITNTEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTVFTVNIHHTGVHGYPVPPFLQIFAFRYLSKILFV 353
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Celegans
Match: acr-21 (pep chromosome:WBcel235:III:6581927:6586549:1 gene:WBGene00000060.1 transcript:F27B3.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:acr-21) HSP 1 Score: 222.631 bits (566), Expect = 2.235e-62 Identity = 124/339 (36.58%), Postives = 194/339 (57.23%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADER-MEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDL 1416
L +LL Y+ RP V + P+ V F SL QI+ +DE +QILT+N W DY + W P LY N+T +HIP+ +W PDI +YN AD + M+ D I+ Y G + W AIF S+CP+ +K++PFDRQ C LK+ W YDG ++++ + +L NY+ N EW LI RA+ V Y CC EPYP I H+ ++R + FY + LILPC L+S + L+ F++P +S K+ LG+ ++ + ++++ + +P + + PLIG Y+ + + L+ L T + + TVN H G + VP +L+ ++ ++ILFV +
Sbjct: 34 LYRDLLYDYNNEVRPSVHSKEPI---------------NVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVTRIHIPSDKIWKPDIILYNNADAQYMKSVMSTDVIVDYLGNIHWPLSAIFTSSCPLDVKHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDL--TNYITNTEWSLIGIRAEKNQVIYSCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDSGEKVTLGITSLLSTTVFLMMVAEGMPPTAEALPLIGIYFGVTIMLVALGTAMTVFTVNIHHTGVHGYPVPPFLQIFAFRYLSKILFVRI 355
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Celegans
Match: unc-63 (Acetylcholine receptor subunit alpha-type unc-63 [Source:UniProtKB/Swiss-Prot;Acc:Q9N587]) HSP 1 Score: 186.037 bits (471), Expect = 1.428e-50 Identity = 120/360 (33.33%), Postives = 194/360 (53.89%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTE------------------------LDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
L +L+ Y+K RPV +N + + V F L L Q++ + E +QI+T+NV + W DY +RW P Y + +++P+ +WLPD+ +YN AD + A + Y+GTVEW P AI+KS C + +++FPFDRQ C++KFG WTY G +++ D E +D ++Y +VEW+++ K + RYPCC P+ DI++ I ++R + FY LI P +S LT ++F+LP++ K+ L ++I I+ + +LL + IPS S PLIG Y M L+TLS + ++T+N H+R +P W+K+L + + L +
Sbjct: 30 LFEDLIADYNKLVRPVSENG---------------ETLVVTFKLKLSQLLDVHEKNQIMTTNVWLQHSWMDYKLRWDPVEYGGVEVLYVPSDTIWLPDVVLYNNADGNYQVTIMTKAKLTYNGTVEWAPPAIYKSMCQIDVEFFPFDRQQCEMKFGSWTYGGLEVDLQHRDKHLEKEIEEDVEGVDGPTKEIVWVVDRGIDLSDYYPSVEWDILNVPGKRHSKRYPCCESPFIDITYEIHLRRKTLFYTVNLIFPSVGISFLTALVFYLPSDGGEKISLCISILISLTVFFLLLVEIIPSTSLVIPLIGKYLLFTMVLVTLSVVVTVVTLNVHYRSPTTHTMPKWMKRLFVDFLPKYLLM 374
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Fly
Match: nAChRalpha2 (gene:FBgn0000039 transcript:FBtr0084639) HSP 1 Score: 219.935 bits (559), Expect = 9.258e-62 Identity = 127/346 (36.71%), Postives = 204/346 (58.96%), Query Frame = 1
Query: 397 KVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFY------DNKTE--LDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
K L ++LL+ Y++ RPV +N V V+ GL L Q++ L+ DQILT+NV + W+D+ +W P Y +T +++P++++WLPDI +YN AD AI+ Y G V W P AIFKS+C + ++YFPFD+Q C +KFG WTYDG ++++ DNK E +D Y +VEW+++ A+ YPCC EPYPDI F+I ++R + FY LI+PC +S L++++F+LPA+S K+ L ++I ++ + +L+ + IPS S + PL+G Y M L+ LS + +I +N H+R + ++ W++ IK ++L +
Sbjct: 46 KRLYDDLLSNYNRLIRPVSNN---------------TDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYNNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFIKRLPKLLLM 376
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Fly
Match: nAChRalpha2 (gene:FBgn0000039 transcript:FBtr0084640) HSP 1 Score: 219.935 bits (559), Expect = 9.258e-62 Identity = 127/346 (36.71%), Postives = 204/346 (58.96%), Query Frame = 1
Query: 397 KVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFY------DNKTE--LDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
K L ++LL+ Y++ RPV +N V V+ GL L Q++ L+ DQILT+NV + W+D+ +W P Y +T +++P++++WLPDI +YN AD AI+ Y G V W P AIFKS+C + ++YFPFD+Q C +KFG WTYDG ++++ DNK E +D Y +VEW+++ A+ YPCC EPYPDI F+I ++R + FY LI+PC +S L++++F+LPA+S K+ L ++I ++ + +L+ + IPS S + PL+G Y M L+ LS + +I +N H+R + ++ W++ IK ++L +
Sbjct: 46 KRLYDDLLSNYNRLIRPVSNN---------------TDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYNNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFIKRLPKLLLM 376
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Fly
Match: nAChRalpha5 (gene:FBgn0028875 transcript:FBtr0300594) HSP 1 Score: 209.534 bits (532), Expect = 1.415e-56 Identity = 114/326 (34.97%), Postives = 196/326 (60.12%), Query Frame = 1
Query: 394 EKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLK 1371
EK L+++LL+ Y+ RPV++ P+ + FGL+L+QI+ +DE +Q+L +NV W D ++RW Y + + IP +W PD+ +YN ADE + + + +++ +G+ + P IFKSTC + I +FPFD Q C++KFG WTYDGF+L++ D +T D ++YV N EWEL+ K + Y CC EPY DI+F I+++R + +Y + LI+PC L++S+ L+ F LP +S K+ LG+ I ++ + + ++ +++P+ S + PL+GTY+ M ++ S ++ +N+H R + E+ W++
Sbjct: 313 EKRLLHDLLDPYNTLERPVLNESDPL---------------QLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQD-ETGGDISSYVLNGEWELLGVPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEMSEWIR 622
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Fly
Match: nAChRalpha5 (gene:FBgn0028875 transcript:FBtr0080594) HSP 1 Score: 209.534 bits (532), Expect = 1.415e-56 Identity = 114/326 (34.97%), Postives = 196/326 (60.12%), Query Frame = 1
Query: 394 EKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLK 1371
EK L+++LL+ Y+ RPV++ P+ + FGL+L+QI+ +DE +Q+L +NV W D ++RW Y + + IP +W PD+ +YN ADE + + + +++ +G+ + P IFKSTC + I +FPFD Q C++KFG WTYDGF+L++ D +T D ++YV N EWEL+ K + Y CC EPY DI+F I+++R + +Y + LI+PC L++S+ L+ F LP +S K+ LG+ I ++ + + ++ +++P+ S + PL+GTY+ M ++ S ++ +N+H R + E+ W++
Sbjct: 313 EKRLLHDLLDPYNTLERPVLNESDPL---------------QLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQD-ETGGDISSYVLNGEWELLGVPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEMSEWIR 622
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Fly
Match: nAChRalpha5 (gene:FBgn0028875 transcript:FBtr0309867) HSP 1 Score: 209.534 bits (532), Expect = 1.415e-56 Identity = 114/326 (34.97%), Postives = 196/326 (60.12%), Query Frame = 1
Query: 394 EKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLK 1371
EK L+++LL+ Y+ RPV++ P+ + FGL+L+QI+ +DE +Q+L +NV W D ++RW Y + + IP +W PD+ +YN ADE + + + +++ +G+ + P IFKSTC + I +FPFD Q C++KFG WTYDGF+L++ D +T D ++YV N EWEL+ K + Y CC EPY DI+F I+++R + +Y + LI+PC L++S+ L+ F LP +S K+ LG+ I ++ + + ++ +++P+ S + PL+GTY+ M ++ S ++ +N+H R + E+ W++
Sbjct: 313 EKRLLHDLLDPYNTLERPVLNESDPL---------------QLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGVKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQD-ETGGDISSYVLNGEWELLGVPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEMSEWIR 622
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Zebrafish
Match: chrna4b (cholinergic receptor, nicotinic, alpha 4b [Source:ZFIN;Acc:ZDB-GENE-090505-3]) HSP 1 Score: 219.55 bits (558), Expect = 3.509e-61 Identity = 133/375 (35.47%), Postives = 209/375 (55.73%), Query Frame = 1
Query: 316 VFLLKCLRCQYQEKLSIKNHPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPP 1440
VF L C+ Q S+ P + E+ L+ L Y+K SRPV N++ V V V FGLS+ Q++ +DE +Q++T+NV W DY +RW P Y+N+T + IP++ +W PDI +YN AD A + Y+G ++W P AI+KS+C + + +FPFD+Q CK+KFG WTYD R I +++DQ +Y + EW +I + +Y CC E YPDI++ +++R FY LI+PC L+S LT+++F+LP+E K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R +P W+++L + R LF +K PP
Sbjct: 7 VFFLLCVHLQLAYVFSMS--PAHAHAEERLLQSLFINYNKLSRPVA-NISDV--------------VLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWNDYKLRWNPEEYENVTSIRIPSEIIWRPDIVLYNNADGDFAVTHLTKAQVFYNGRIKWKPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYD--RAKIDLISMASDVDQMDYWESGEWVIINAVGTYNIKKYECCTEIYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECAEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSSRTHSMPHWVRQLFLHLVPRYLF------MKRPP 356
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Zebrafish
Match: chrna10a (cholinergic receptor, nicotinic, alpha 10a [Source:ZFIN;Acc:ZDB-GENE-060503-725]) HSP 1 Score: 214.542 bits (545), Expect = 3.796e-60 Identity = 129/348 (37.07%), Postives = 201/348 (57.76%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLGFILKTPPP 1443
L+N+L N Y RPV E + I VT++ LS QI+ +DE +QILT+ + W D ++ W YD + + IP Y+W PDI +YN AD+ + + +I++DG + W AI KS+C V + +FPFD Q C+L +G WTY+G +L+I + D + V NVEWE++ AK + Y CC +PYPD+++ + ++R ++FY + L++PC ++S L + F+LPA+S K+ LG+ + +A + +L+ + +P S + PLIG YY MT+IT ST L + +N H G + K VP W KK +++ ARI FV ++G TP P
Sbjct: 33 LLNDLFNNYTSALRPV-------------EDTEDILNVTLQITLS--QIIDMDERNQILTAYLWIRQVWIDKYLTWNKENYDGLDTIRIPGSYVWRPDIVLYNSADDHFTSTMDTNVVIRHDGQIMWDAPAITKSSCKVDVSFFPFDAQQCRLTYGSWTYNGNQLDI--LNAMESADLADLVDNVEWEVLGMPAKRNIILYGCCADPYPDVTYTLKLKRRASFYVFNLLIPCVMISFLAPLGFYLPADSGEKVSLGVTVMLALTVFQLLVAEIMPP-SENVPLIGKYYIATMTMITASTALTIFVMNIHHCGPDAKPVPDWAKKFILQYLARICFVYEVGENCMTPQP 362
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Zebrafish
Match: chrna10a (cholinergic receptor, nicotinic, alpha 10a [Source:ZFIN;Acc:ZDB-GENE-060503-725]) HSP 1 Score: 214.157 bits (544), Expect = 4.283e-60 Identity = 129/348 (37.07%), Postives = 201/348 (57.76%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLGFILKTPPP 1443
L+N+L N Y RPV E + I VT++ LS QI+ +DE +QILT+ + W D ++ W YD + + IP Y+W PDI +YN AD+ + + +I++DG + W AI KS+C V + +FPFD Q C+L +G WTY+G +L+I + D + V NVEWE++ AK + Y CC +PYPD+++ + ++R ++FY + L++PC ++S L + F+LPA+S K+ LG+ + +A + +L+ + +P S + PLIG YY MT+IT ST L + +N H G + K VP W KK +++ ARI FV ++G TP P
Sbjct: 28 LLNDLFNNYTSALRPV-------------EDTEDILNVTLQITLS--QIIDMDERNQILTAYLWIRQVWIDKYLTWNKENYDGLDTIRIPGSYVWRPDIVLYNSADDHFTSTMDTNVVIRHDGQIMWDAPAITKSSCKVDVSFFPFDAQQCRLTYGSWTYNGNQLDI--LNAMESADLADLVDNVEWEVLGMPAKRNIILYGCCADPYPDVTYTLKLKRRASFYVFNLLIPCVMISFLAPLGFYLPADSGEKVSLGVTVMLALTVFQLLVAEIMPP-SENVPLIGKYYIATMTMITASTALTIFVMNIHHCGPDAKPVPDWAKKFILQYLARICFVYEVGENCMTPQP 357
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Zebrafish
Match: CR388402.1 (cholinergic receptor, nicotinic, alpha 9 [Source:NCBI gene;Acc:568807]) HSP 1 Score: 213.001 bits (541), Expect = 1.676e-59 Identity = 144/432 (33.33%), Postives = 222/432 (51.39%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERR-ECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLGFILKTPPPVETIKTKQCINPSFLNKAPPKHLPSSDFIDKTIQGAQFYDQFYQSNF---PQRNQNSNIHYLHSNHMRNMFESSDVRNSRPNT 1683
L+N+L+ GY RPV D + + + V ++L QI +DE +Q+LT+ + W D ++ W YD + + IP+ +W PDI +YN ADE + + +++Y+G + W AI KS+C V + YFPFD Q C L FG WTY+G +++I D +++V NVEWE A + Y CC +PYPDI++ +L++R S+FY + L+LPCFL+S L + F+LPA+S K+ LG+ + +A + +++ +S+P S S PLIG YY MT+IT ST L + +N HF G K VP W K L I + ++I FV ++G E T + F ++ P L + DK D+ +S F R+ Y H N R +R ++
Sbjct: 28 LLNDLMEGYSNALRPVED---------------TDKALNVTLQITLSQIKDMDERNQVLTTYLWVRQIWHDAYLSWDKEEYDGLEVIRIPSNLVWRPDIVLYNNADEEDSSGPPDTNVVLRYNGEITWDSPAITKSSCKVDVSYFPFDSQECNLTFGSWTYNGNQVDIAM--GMESGDLSDFVDNVEWECHGMPAVKNVIMYGCCSDPYPDITYTVLLKRRSSFYIFNLLLPCFLISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLMVAESMP-PSESVPLIGKYYIATMTMITASTSLTIFIMNIHFCGAEAKPVPHWAKVLIIDYMSKIFFVYEVG---------ENCTTPESDRGPFFSEDPLASLERDGYFDKGFYEDCHLDERIRSQFNGYSHRDHRHGNGYHHKNSSYRQHRHEQQRRTRSSS 432
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Zebrafish
Match: chrna9 (cholinergic receptor, nicotinic, alpha 9 [Source:ZFIN;Acc:ZDB-GENE-090312-63]) HSP 1 Score: 213.386 bits (542), Expect = 2.268e-59 Identity = 144/432 (33.33%), Postives = 223/432 (51.62%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERR-ECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLGFILKTPPPVETIKTKQCINPSFLNKAPPKHLPSSDFIDKTIQGAQFYDQFYQSNF---PQRNQNSNIHYLHSNHMRNMFESSDVRNSRPNT 1683
L+N+L+ GY RPV D + + + V ++L QI +DE +Q+LT+ + W D ++ W YD + + IP+ +W PDI +YN ADE + + +++Y+G + W AI KS+C V + YFPFD Q C L FG WTY+G +++I D +++V NVEWE A + Y CC +PYPDI++ +L++R S+FY + L+LPCFL+S L + F+LPA+S K+ LG+ + +A + +++ +S+P S S PLIG YY MT+IT ST L + +N HF G K VP W K L I + ++I FV ++G E T + F ++ P L + DK D+ +S F R+ Y H N + R +R ++
Sbjct: 28 LLNDLMEGYSNALRPVED---------------TDKALNVTLQITLSQIKDMDERNQVLTTYLWVRQIWHDAYLSWDKEEYDGLEVIRIPSNLVWRPDIVLYNNADEEDSSGPPDTNVVLRYNGEITWDSPAITKSSCKVDVSYFPFDSQECNLTFGSWTYNGNQVDIAM--GMESGDLSDFVDNVEWECHGMPAVKNVIMYGCCSDPYPDITYTVLLKRRSSFYIFNLLLPCFLISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLMVAESMP-PSESVPLIGKYYIATMTMITASTSLTIFIMNIHFCGAEAKPVPHWAKVLIIDYMSKIFFVYEVG---------ENCTTPESDRGPFFSEDPLASLERDGYFDKGFYEDCHLDERIRSQFNGYSHRDHRHGNGYHHKNSSYRQHRNEQQRRTRSSS 432
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Xenopus
Match: CHRNA2 (cholinergic receptor, nicotinic alpha 2 [Source:NCBI gene;Acc:100495873]) HSP 1 Score: 219.164 bits (557), Expect = 6.954e-62 Identity = 143/467 (30.62%), Postives = 250/467 (53.53%), Query Frame = 1
Query: 391 TEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVETIKTKQCINPSFLNKAPPKHLPSSDFIDKTIQGAQFYDQFYQSNFPQRNQNSNIHYLHSNHMRNMFESSDVRNSRPNTPDCAADV-PSVFDRYPTAESISGNEEELDDDLDFRQ 1788
E+ L L GY++ SRPV NT++ V V+FGLS+ Q++ +DE +Q++T+NV W DY +RW P YDN+T + +P++ +W+PDI +YN AD A + ++G V+W P AI+KS+C + + +FPFD+Q CK+KFG WTYD L++ + +L +Y + EW ++ K+ + +Y CC E YPDI+++ +++R FY LI+PC L+S LT+++F+LP++ K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R + ++P W++ + + H R LF+ + P PVE + ++ + L + K+ +D DK + + + NQ+ Y +++H+ +S R+S T + + + PSV I+ + D D ++
Sbjct: 31 AEERLFKRLFTGYNRWSRPVP---------NTSD------VVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWNPADYDNVTSIRVPSEMIWIPDIVLYNNADGEFAITHMTKAHLFHNGKVKWVPPAIYKSSCSIDVTFFPFDQQSCKMKFGSWTYDKAWLDLESMERNVDL--KDYWESGEWAIVNAVGKYNSKKYDCCTEIYPDITYYFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPLWVRSVFLDHIPRWLFMK-----RPPAPVEEVVSQY--DAPELKLSTSKYWMETDVDDKWAEPEAELQTCHVRHMTTHNQSLQYRYDYNHHVSGG-QSQTPRHSSTETAESSFLLSPSVLKALEGVHYIANHLRAEDADFSVKE 472
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Xenopus
Match: prepl (prolyl endopeptidase-like [Source:Xenbase;Acc:XB-GENE-981635]) HSP 1 Score: 218.394 bits (555), Expect = 9.521e-62 Identity = 127/336 (37.80%), Postives = 199/336 (59.23%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
L+N+L Y RPV E VT++ LS QI+ +DE +QIL + + W D ++RW YD + + IP+ Y+W PDI +YN AD++ E + +I+YDG + W AI KS+C V + +FPFD Q C+L FG WTY+G +++I + + +L ++V NVEWE++ AK + + Y CC EPYPD+++ ++++R ++FY + L+LPC ++S L + F+LPA+S K+ LG+ + +A + +L+ +S+P S + PLIG YY MT+IT ST L + +N H G K VP W KK +++ +RI FV
Sbjct: 28 LMNDLFANYSNALRPV-------------EDMDKAMNVTLQVTLS--QIIDMDERNQILMAYLWIRQVWFDAYLRWNKEDYDGLDTIRIPSSYVWRPDIVLYNNADDQFTGSMETNVVIRYDGQIMWDSPAITKSSCKVDVSFFPFDGQQCRLTFGSWTYNGNQIDILNHLDTGDL--TDFVENVEWEILGMPAKKSVITYGCCSEPYPDVTYTLILKRRASFYIFNLLLPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLLVAESMP-PSENVPLIGKYYIATMTMITASTALTIFIMNIHHCGPEAKPVPQWAKKFILQYMSRIFFV 345
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Xenopus
Match: CHRNA2 (cholinergic receptor, nicotinic alpha 2 [Source:NCBI gene;Acc:100495873]) HSP 1 Score: 217.624 bits (553), Expect = 1.526e-61 Identity = 143/462 (30.95%), Postives = 248/462 (53.68%), Query Frame = 1
Query: 394 EKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVETIKTKQCINPSFLNKAPPKHLPSSDFIDKTIQGAQFYDQFYQSNFPQRNQNSNIHYLHSNHMRNMFESSDVRNSRPNTPDCAADV-PSVFDRYPTAESISGNEEELDDDL 1776
E+ L L GY++ SRPV NT++ V V+FGLS+ Q++ +DE +Q++T+NV W DY +RW P YDN+T + +P++ +W+PDI +YN AD A + ++G V+W P AI+KS+C + + +FPFD+Q CK+KFG WTYD L++ + +L +Y + EW ++ K+ + +Y CC E YPDI+++ +++R FY LI+PC L+S LT+++F+LP++ K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R + ++P W++ + + H R LF+ + P PVE + ++ + L + K+ +D DK + + + NQ+ Y +++H+ +S R+S T + + + PSV I+ + D D
Sbjct: 32 EERLFKRLFTGYNRWSRPVP---------NTSD------VVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWNPADYDNVTSIRVPSEMIWIPDIVLYNNADGEFAITHMTKAHLFHNGKVKWVPPAIYKSSCSIDVTFFPFDQQSCKMKFGSWTYDKAWLDLESMERNVDL--KDYWESGEWAIVNAVGKYNSKKYDCCTEIYPDITYYFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPLWVRSVFLDHIPRWLFMK-----RPPAPVEEVVSQY--DAPELKLSTSKYWMETDVDDKWAEPEAELQTCHVRHMTTHNQSLQYRYDYNHHVSGG-QSQTPRHSSTETAESSFLLSPSVLKALEGVHYIANHLRAEDADF 468
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Xenopus
Match: CHRNA9 (cholinergic receptor, nicotinic alpha 9 [Source:NCBI gene;Acc:100493319]) HSP 1 Score: 211.846 bits (538), Expect = 1.409e-59 Identity = 123/342 (35.96%), Postives = 196/342 (57.31%), Query Frame = 1
Query: 397 KVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLG 1419
++L +L Y RPV D + + + V ++L QI +DE +QILT+ + W D +++W YD + + IP+ +W PDI +YN AD+ E + +++YDG + W AI KS+C V + YFPFD Q C L FG WTY+G +++I + D +++V NVEWE+ A + Y CC EPYPDI+F ++++R S+FY + L++PC ++S L + F+LPA+S K+ LG+ + +A + +++ +S+P S S PLIG YY MT+IT ST L +I +N H G K +P W + + + + ++I FV D+G
Sbjct: 16 QMLFRDLFEDYSNALRPVED---------------TDKALNVSLQITLSQIKDVDERNQILTAYLWIRLSWYDAYLKWDRDEYDGLDSIRIPSNMVWRPDIVLYNKADDEFSEPVNTNVVLRYDGKITWDSPAITKSSCVVDVSYFPFDNQQCNLTFGSWTYNGNQVDII--NTMDSGDLSDFVENVEWEMQGMPAVKNVITYGCCSEPYPDITFTLILKRRSSFYIFNLLIPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLMVAESMP-PSESVPLIGKYYIATMTMITASTALTIIIMNIHLCGPEAKPIPRWARIVILDYMSKIFFVYDVG 339
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Xenopus
Match: CHRNA9 (cholinergic receptor, nicotinic alpha 9 [Source:NCBI gene;Acc:100493319]) HSP 1 Score: 211.846 bits (538), Expect = 2.854e-59 Identity = 123/342 (35.96%), Postives = 196/342 (57.31%), Query Frame = 1
Query: 397 KVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLG 1419
++L +L Y RPV D + + + V ++L QI +DE +QILT+ + W D +++W YD + + IP+ +W PDI +YN AD+ E + +++YDG + W AI KS+C V + YFPFD Q C L FG WTY+G +++I + D +++V NVEWE+ A + Y CC EPYPDI+F ++++R S+FY + L++PC ++S L + F+LPA+S K+ LG+ + +A + +++ +S+P S S PLIG YY MT+IT ST L +I +N H G K +P W + + + + ++I FV D+G
Sbjct: 39 QMLFRDLFEDYSNALRPVED---------------TDKALNVSLQITLSQIKDVDERNQILTAYLWIRLSWYDAYLKWDRDEYDGLDSIRIPSNMVWRPDIVLYNKADDEFSEPVNTNVVLRYDGKITWDSPAITKSSCVVDVSYFPFDNQQCNLTFGSWTYNGNQVDII--NTMDSGDLSDFVENVEWEMQGMPAVKNVITYGCCSEPYPDITFTLILKRRSSFYIFNLLIPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLMVAESMP-PSESVPLIGKYYIATMTMITASTALTIIIMNIHLCGPEAKPIPRWARIVILDYMSKIFFVYDVG 362
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Mouse
Match: Chrna9 (cholinergic receptor, nicotinic, alpha polypeptide 9 [Source:MGI Symbol;Acc:MGI:1202403]) HSP 1 Score: 215.312 bits (547), Expect = 6.117e-61 Identity = 142/410 (34.63%), Postives = 218/410 (53.17%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLGFILKTP----PPVETIKTKQCINPSFLNKAPPKHLPSSDFIDKTIQGAQFYDQFYQSNFPQRNQNSNIHY 1617
L ++L Y RPV E ++ VT++ LS QI +DE +QILT+ + W D ++ W YD + + IP+ +W PDI +YN AD+ E + +++YDG + W AI KS+C V + YFPFD Q C L FG WTY+G +++I ++ D ++++ +VEWE+ A + Y CC EPYPD++F +L++R S+FY L++PC L+S L + F+LPA S K+ LG+ I +A + +++ + +P AS + PLIG YY M LIT ST L ++ +N HF G + VP W K + +K+ +RILFV D+G +P P + K + S L + K L + K ++ D YQ PQ + Y
Sbjct: 34 LFSDLFEDYSNALRPV-------------EDTDAVLNVTLQVTLS--QIKDMDERNQILTAYLWIRQTWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDGLITWDSPAITKSSCVVDVTYFPFDSQQCNLTFGSWTYNGNQVDI--FNALDSGDLSDFIEDVEWEVQGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMP-ASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWAKVVILKYMSRILFVYDVGESCLSPRHSQEPEQITKVYGKLPGSNLKASRNKDLSRKKELRKLLKN----DLGYQGGIPQNTDSYCARY 421
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Mouse
Match: Chrna4 (cholinergic receptor, nicotinic, alpha polypeptide 4 [Source:MGI Symbol;Acc:MGI:87888]) HSP 1 Score: 211.075 bits (536), Expect = 4.588e-58 Identity = 122/350 (34.86%), Postives = 206/350 (58.86%), Query Frame = 1
Query: 382 KSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILK 1431
++ E+ L+ L +GY+K SRPV N++ V V V FGLS+ Q++ +DE +Q++T+NV W DY +RW P Y+N+T + IP++ +W PDI +YN AD A + YDG V+W P AI+KS+C + + +FPFD+Q C +KFG WTYD ++++ ++ +DQ ++ + EW ++ + T +Y CC E YPDI++ +++R FY LI+PC L+S LT+++F+LP+E K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R +P W++++ + R+LF+ ++K
Sbjct: 35 RAHAEERLLKRLFSGYNKWSRPVA-NISDV--------------VLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPGDYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFYDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSMHSR--VDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKVTLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPAWVRRVFLDIVPRLLFMKRPSVVK 367
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Mouse
Match: Chrna4 (cholinergic receptor, nicotinic, alpha polypeptide 4 [Source:MGI Symbol;Acc:MGI:87888]) HSP 1 Score: 211.075 bits (536), Expect = 5.922e-58 Identity = 122/350 (34.86%), Postives = 206/350 (58.86%), Query Frame = 1
Query: 382 KSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILK 1431
++ E+ L+ L +GY+K SRPV N++ V V V FGLS+ Q++ +DE +Q++T+NV W DY +RW P Y+N+T + IP++ +W PDI +YN AD A + YDG V+W P AI+KS+C + + +FPFD+Q C +KFG WTYD ++++ ++ +DQ ++ + EW ++ + T +Y CC E YPDI++ +++R FY LI+PC L+S LT+++F+LP+E K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R +P W++++ + R+LF+ ++K
Sbjct: 35 RAHAEERLLKRLFSGYNKWSRPVA-NISDV--------------VLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPGDYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFYDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSMHSR--VDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKVTLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPAWVRRVFLDIVPRLLFMKRPSVVK 367
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Mouse
Match: Chrna10 (cholinergic receptor, nicotinic, alpha polypeptide 10 [Source:MGI Symbol;Acc:MGI:3609260]) HSP 1 Score: 201.06 bits (510), Expect = 3.686e-56 Identity = 121/336 (36.01%), Postives = 186/336 (55.36%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
L +L Y RPV D +Q++ VT+E LS QI+ +DE +Q+LT + W D ++ W P Y ++ + IP+ +W PDI +YN AD + + ++++DG V W AI +S+C V + FPFD Q C L FG WT+ G +L++ T ++V NVEW ++ A+ + Y CC EPYPD++F +L++R +A Y L+LPC +S L + F LPA+S K+ LG+ + +A + ++L +S+P A S PLIG YY MT++T ST L ++ +N H+ G N VP W + L + H A+ L V
Sbjct: 33 LFRDLFANYTSALRPVADT------------DQTLN-VTLEVTLS--QIIDMDERNQVLTLYLWIRQEWTDAYLHWDPKAYGDLDAIRIPSSLVWRPDIVLYNKADTQPPASASTNVVVRHDGAVRWDAPAITRSSCRVDVSAFPFDAQRCGLTFGSWTHGGHQLDVR--PRGTSASLADFVENVEWRVLGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYVCNLLLPCVFISLLAPLAFHLPADSGEKVSLGVTVLLALTVFQLILAESMPPA-ESVPLIGKYYMATMTMVTFSTALTILIMNLHYCGPNAHPVPAWARVLLLGHLAKGLCV 350
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Mouse
Match: Chrna6 (cholinergic receptor, nicotinic, alpha polypeptide 6 [Source:MGI Symbol;Acc:MGI:106213]) HSP 1 Score: 200.675 bits (509), Expect = 1.852e-55 Identity = 115/340 (33.82%), Postives = 192/340 (56.47%), Query Frame = 1
Query: 391 TEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
+E+ L + L Y++ RPV + PV TV F L++ Q+ +DE++QI+ +N+ + WKDY +RW P YD I + +P +W PDI +YN A + + A++KYDG + W P AIFKS+CP+ I +FPFD Q C LKFG WTYD +++ +K +D N++ N EWE++ ++Y CC E Y DI++ ++R FY LI+PC +S LT+++F+LP++ K+ L +++ ++ + ++++ ++IPS S PL+G Y M +TLS + + +N H+R +P W+K + ++ IL +
Sbjct: 33 SEEQLFHRLFAHYNRFIRPVENVSDPV---------------TVHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTEYDGIETLRVPADNIWKPDIVLYNNAVGDFQVEGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK--VDMNDFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHTMPKWVKTIFLQAFPSILMM 355
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. UniProt/SwissProt
Match: sp|Q9I8C7|ACH10_CHICK (Neuronal acetylcholine receptor subunit alpha-10 OS=Gallus gallus OX=9031 GN=CHRNA10 PE=3 SV=1) HSP 1 Score: 216.468 bits (550), Expect = 7.792e-61 Identity = 129/337 (38.28%), Postives = 193/337 (57.27%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNI-TFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
L+++L Y RP AE + VT++ LS QI+ +DE +Q+LTS + W D H+ W Y I + IP+ Y+W PDI +YN ADER E + +++ DG + W AI KS+C V + YFPFD Q C+L FG WTY+G ++++ D D ++V NVEWE++ A V Y CC EPYPD+++ +L++R ++FY + L+LPC ++S L + F+LPA+S K+ LG+ + +A + +L+ +S+P S S PLIG YY MT+IT ST L + +N H G + VP W ++L + H AR L V
Sbjct: 35 LLHDLFANYSSALRP-------------AEDTERALNVTLQVTLS--QIIDMDERNQVLTSYLWVRQAWLDAHLAWDKDAYGGIDSIRIPSSYVWRPDIVLYNNADERFGGSMETNVVLRSDGHIMWDSPAITKSSCKVDVSYFPFDGQQCRLTFGSWTYNGNQIDLRNLLDTG---DLTDFVENVEWEVLGMPATRNVVTYGCCSEPYPDVTYTLLLRRRASFYIFNLLLPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLLVAESMPP-SESVPLIGKYYIATMTMITASTALTIFIMNIHHCGPGARPVPPWARRLILHHLARALCV 352
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. UniProt/SwissProt
Match: sp|P17644|ACH2_DROME (Acetylcholine receptor subunit alpha-like 2 OS=Drosophila melanogaster OX=7227 GN=nAChRalpha2 PE=2 SV=1) HSP 1 Score: 219.935 bits (559), Expect = 9.280e-61 Identity = 127/346 (36.71%), Postives = 204/346 (58.96%), Query Frame = 1
Query: 397 KVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFY------DNKTE--LDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
K L ++LL+ Y++ RPV +N V V+ GL L Q++ L+ DQILT+NV + W+D+ +W P Y +T +++P++++WLPDI +YN AD AI+ Y G V W P AIFKS+C + ++YFPFD+Q C +KFG WTYDG ++++ DNK E +D Y +VEW+++ A+ YPCC EPYPDI F+I ++R + FY LI+PC +S L++++F+LPA+S K+ L ++I ++ + +L+ + IPS S + PL+G Y M L+ LS + +I +N H+R + ++ W++ IK ++L +
Sbjct: 46 KRLYDDLLSNYNRLIRPVSNN---------------TDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYNNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFIKRLPKLLLM 376
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. UniProt/SwissProt
Match: sp|P23414|ACH1_SCHGR (Acetylcholine receptor subunit alpha-L1 OS=Schistocerca gregaria OX=7010 PE=2 SV=1) HSP 1 Score: 219.164 bits (557), Expect = 1.207e-60 Identity = 124/345 (35.94%), Postives = 207/345 (60.00%), Query Frame = 1
Query: 397 KVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNI-----TFYDNKTE--LDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
K L ++LL+ Y++ RPV +N V V+ GL L Q++ L+ DQILT+NV + W+D+ RW P Y +T +++P++++WLPDI +YN AD A++ + G V W P AIFKS+C + ++YFPFD+Q C +KFG WTYDG ++++ + DNK + +D Y +VEW+++ A+ YPCC EPYPDI F+I ++R + FY LI+PC +S L++++F+LPA+S K+ L ++I ++ + +L+ + IPS S + PL+G Y M L+ LS + ++ +N H+R + ++ W++K+ I+ ++L +
Sbjct: 28 KRLYDDLLSNYNRLIRPVSNN---------------TDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFRWDPAEYGGVTELYVPSEHIWLPDIVLYNNADGEYVVTTMTKAVLHHTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHINQKYDDNKVKVGIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIVPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMVLVGLSVVITIMVLNVHYRKPSTHKMAPWVRKVFIRRLPKLLLM 357
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. UniProt/SwissProt
Match: sp|P43144|ACHA9_RAT (Neuronal acetylcholine receptor subunit alpha-9 OS=Rattus norvegicus OX=10116 GN=Chrna9 PE=1 SV=2) HSP 1 Score: 215.698 bits (548), Expect = 2.839e-60 Identity = 142/410 (34.63%), Postives = 218/410 (53.17%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLGFILKTP----PPVETIKTKQCINPSFLNKAPPKHLPSSDFIDKTIQGAQFYDQFYQSNFPQRNQNSNIHY 1617
L ++L Y RPV E ++ VT++ LS QI +DE +QILT+ + W D ++ W YD + + IP+ +W PDI +YN AD+ E + +++YDG + W AI KS+C V + YFPFD Q C L FG WTY+G +++I ++ D ++++ +VEWE+ A + Y CC EPYPD++F +L++R S+FY L++PC L+S L + F+LPA S K+ LG+ I +A + +++ + +P AS + PLIG YY M LIT ST L ++ +N HF G + VP W K + +K+ +RILFV D+G +P P + K + S L + K L + K ++ D YQ PQ + Y
Sbjct: 34 LFSDLFEDYSSALRPV-------------EDTDAVLNVTLQVTLS--QIKDMDERNQILTAYLWIRQTWHDAYLTWDRDQYDRLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDGLITWDSPAITKSSCVVDVTYFPFDSQQCNLTFGSWTYNGNQVDI--FNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMP-ASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWAKVVILKYMSRILFVYDVGESCLSPRHSQEPEQVTKVYSKLPESNLKTSRNKDLSRKKEVRKLLKN----DLGYQGGIPQNTDSYCARY 421
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. UniProt/SwissProt
Match: sp|Q9UGM1|ACHA9_HUMAN (Neuronal acetylcholine receptor subunit alpha-9 OS=Homo sapiens OX=9606 GN=CHRNA9 PE=1 SV=2) HSP 1 Score: 211.46 bits (537), Expect = 9.936e-59 Identity = 127/340 (37.35%), Postives = 195/340 (57.35%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLG 1419
L N+L Y RPV E + VT++ LS QI +DE +QILT+ + W D ++ W YD + + IP+ +W PDI +YN AD+ E + +++YDG + W AI KS+C V + YFPFD Q C L FG WTY+G +++I ++ D ++++ +VEWE+ A + Y CC EPYPD++F +L++R S+FY L++PC L+S L + F+LPA S K+ LG+ I +A + +++ + +P AS + PLIG YY M LIT ST L ++ +N HF G + VP W + + +K+ +R+LFV D+G
Sbjct: 34 LFNDLFEDYSNALRPV-------------EDTDKVLNVTLQITLS--QIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDI--FNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMP-ASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWARVVILKYMSRVLFVYDVG 355
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. TrEMBL
Match: A0A1I8H1Z4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 412.92 bits (1060), Expect = 7.668e-132 Identity = 227/385 (58.96%), Postives = 287/385 (74.55%), Query Frame = 1
Query: 322 LLKC-----LRCQYQEK------LSIKNHPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQS---------IQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDL 1416
LL+C L CQ+ + +S P+ EK LI +LL YDK+SRPV+D P Y ER + IQQVTVEFGL L+QI+ LDEM+Q+LT+++ +LY W DYH+RW+P D I VHIPTK +WLPDI++YNYADER+EERR+ A + Y G VEWHPMAI+KS C ++IK+FPFD+Q C LKFGPWTYDG+R+NI++Y N T+ D + + EW ++ +AK+ YPCC EPY DI+F I ++R++AFY +ILILPCFLLSSLTLVLFWLP E+PAKMVLGMNIF+AFFLL++LLEK PSAS SFPLIG YYC+NM +ITLSTFL +I VNFHFRGDNR+EVP+WLKKL I+HG+R+LFV+L
Sbjct: 3 LLECIAALLLLCQWAPRQPILTAVSALGQPQMKMAEKNLIKQLLQHYDKKSRPVIDA-DPPYGTPKIERRKEKHANSSTIPIQQVTVEFGLRLVQILDLDEMEQVLTTSMISLYEWTDYHLRWEPEDEDGIMFVHIPTKDIWLPDIALYNYADERLEERRDVAAKVHYTGLVEWHPMAIYKSACEIKIKFFPFDKQVCWLKFGPWTYDGWRVNISYYHNMTKFDLEEMIDSPEWTILSHKAKYNEEVYPCCPEPYVDITFWIWIRRSTAFYTFILILPCFLLSSLTLVLFWLPPETPAKMVLGMNIFVAFFLLMLLLEKQTPSASDSFPLIGQYYCLNMGIITLSTFLSVIVVNFHFRGDNRQEVPYWLKKLAIQHGSRLLFVNL 386
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. TrEMBL
Match: A0A267E180 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032313g2 PE=3 SV=1) HSP 1 Score: 414.846 bits (1065), Expect = 1.139e-130 Identity = 229/393 (58.27%), Postives = 290/393 (73.79%), Query Frame = 1
Query: 322 LLKC-----LRCQYQEK------LSIKNHPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQS---------IQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPP 1440
LL+C L CQ+ + +S P+ EK LI +LL YDK+SRPV+D P Y ER + IQQVTVEFGL L+QI+ LDEM+Q+LT+++ +LY W DYH+RW+P D I VHIPTK +WLPDI++YNYADER+EERR+ A + Y G VEWHPMAI+KS C ++IK+FPFD+Q C LKFGPWTYDG+R+NI++Y N T+ D + + EW ++ +AK+ YPCC EPY DI+F I ++R++AFY +ILILPCFLLSSLTLVLFWLP E+PAKMVLGMNIF+AFFLL++LLEK PSAS SFPLIG YYC+NM +ITLSTFL +I VNFHFRGDNR+EVP+WLKKL I+HG+R+LFV+L + PP
Sbjct: 3 LLECIAALLLLCQWAPRQPILTAVSALGQPQMKMAEKNLIKQLLQHYDKKSRPVIDA-DPPYGTPKIERRKEKHANSSTIPIQQVTVEFGLRLVQILDLDEMEQVLTTSMISLYEWTDYHLRWEPEDEDGIMFVHIPTKDIWLPDIALYNYADERLEERRDVAAKVHYTGLVEWHPMAIYKSACEIKIKFFPFDKQVCWLKFGPWTYDGWRVNISYYHNMTKFDLEEMIDSPEWTILSHKAKYNEEVYPCCPEPYVDITFWIWIRRSTAFYTFILILPCFLLSSLTLVLFWLPPETPAKMVLGMNIFVAFFLLMLLLEKQTPSASDSFPLIGQYYCLNMGIITLSTFLSVIVVNFHFRGDNRQEVPYWLKKLAIQHGSRLLFVNLN---RKPP 391 HSP 2 Score: 104.375 bits (259), Expect = 2.751e-19 Identity = 44/70 (62.86%), Postives = 61/70 (87.14%), Query Frame = 1
Query: 2059 RRINLVTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILSLILFFPKAGND 2268
RRIN++TKD+ DI+K L +IQK +EN+E+VNK+V EWR+V LVLDR FF++YV+ I+LS+I FFPK+GN+
Sbjct: 561 RRINMLTKDVQDIVKALRYIQKLHENREKVNKVVQEWRSVALVLDRLFFLIYVLTIMLSIIFFFPKSGNE 630
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. TrEMBL
Match: A0A267F2A9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032313g1 PE=3 SV=1) HSP 1 Score: 414.846 bits (1065), Expect = 1.173e-130 Identity = 229/393 (58.27%), Postives = 290/393 (73.79%), Query Frame = 1
Query: 322 LLKC-----LRCQYQEK------LSIKNHPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQS---------IQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPP 1440
LL+C L CQ+ + +S P+ EK LI +LL YDK+SRPV+D P Y ER + IQQVTVEFGL L+QI+ LDEM+Q+LT+++ +LY W DYH+RW+P D I VHIPTK +WLPDI++YNYADER+EERR+ A + Y G VEWHPMAI+KS C ++IK+FPFD+Q C LKFGPWTYDG+R+NI++Y N T+ D + + EW ++ +AK+ YPCC EPY DI+F I ++R++AFY +ILILPCFLLSSLTLVLFWLP E+PAKMVLGMNIF+AFFLL++LLEK PSAS SFPLIG YYC+NM +ITLSTFL +I VNFHFRGDNR+EVP+WLKKL I+HG+R+LFV+L + PP
Sbjct: 3 LLECIAALLLLCQWAPRQPILTAVSALGQPQMKMAEKNLIKQLLQHYDKKSRPVIDA-DPPYGTPKIERRKEKHANSSTIPIQQVTVEFGLRLVQILDLDEMEQVLTTSMISLYEWTDYHLRWEPEDEDGIMFVHIPTKDIWLPDIALYNYADERLEERRDVAAKVHYTGLVEWHPMAIYKSACEIKIKFFPFDKQVCWLKFGPWTYDGWRVNISYYHNMTKFDLEEMIDSPEWTILSHKAKYNEEVYPCCPEPYVDITFWIWIRRSTAFYTFILILPCFLLSSLTLVLFWLPPETPAKMVLGMNIFVAFFLLMLLLEKQTPSASDSFPLIGQYYCLNMGIITLSTFLSVIVVNFHFRGDNRQEVPYWLKKLAIQHGSRLLFVNLN---RKPP 391 HSP 2 Score: 104.375 bits (259), Expect = 2.760e-19 Identity = 44/70 (62.86%), Postives = 61/70 (87.14%), Query Frame = 1
Query: 2059 RRINLVTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILSLILFFPKAGND 2268
RRIN++TKD+ DI+K L +IQK +EN+E+VNK+V EWR+V LVLDR FF++YV+ I+LS+I FFPK+GN+
Sbjct: 562 RRINMLTKDVQDIVKALRYIQKLHENREKVNKVVQEWRSVALVLDRLFFLIYVLTIMLSIIFFFPKSGNE 631
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. TrEMBL
Match: A0A4E0RKE5 (Acetylcholine-gated chloride channel subunit OS=Fasciola hepatica OX=6192 GN=D915_002089 PE=3 SV=1) HSP 1 Score: 417.927 bits (1073), Expect = 5.185e-130 Identity = 226/353 (64.02%), Postives = 281/353 (79.60%), Query Frame = 1
Query: 361 SIKN-HPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDL 1416
SI+N + + WTEK LI +LL+ Y+KR+RPVVDN +PV ++ + ++QQ+TV FGL LIQI+ L+E +Q LT +V++LYRW DYH+ W P Y+NITH+ IPT +W+PDI++YNYADER+EERREC A I ++G VEWHPMAI+KSTCPV+IKYFP+DRQ C L+FGPWTYD R+NI+FY+ L+ +YV + EW LI T YPCC E Y DI F + ++R A+YNYILILPCFLLSSLTLVLFWLP E+PAKMVLGMNIF+AFFLL++LLEKSIP+ASSSFPLIG YYCINMTL+TLSTFLCLI VN HFRGD R EVP WL+KL I+HGAR+L V++
Sbjct: 24 SIENPYSKGKWTEKSLIKDLLHDYEKRARPVVDNKSPVIQLG----DLTVQQITVGFGLGLIQILDLNENEQTLTVSVKSLYRWPDYHLVWNPEEYENITHITIPTDKIWIPDIALYNYADERLEERRECAARIDHNGIVEWHPMAIYKSTCPVKIKYFPYDRQECNLRFGPWTYDNSRVNISFYE-AVNLNLKDYVVSPEWNLISTDVIMRQRAYPCCPEKYSDIFFRMTIERQPAYYNYILILPCFLLSSLTLVLFWLPPETPAKMVLGMNIFVAFFLLLLLLEKSIPNASSSFPLIGNYYCINMTLVTLSTFLCLIVVNLHFRGDRRTEVPHWLRKLAIQHGARLLLVNV 371 HSP 2 Score: 88.9669 bits (219), Expect = 2.400e-14 Identity = 33/70 (47.14%), Postives = 59/70 (84.29%), Query Frame = 1
Query: 2059 RRINLVTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILSLILFFPKAGND 2268
RR+ V +D+S+I++ + F+Q+ NENK +VNK+++EWR VG+VLDR FF++Y++A+ +S++L+FP++G +
Sbjct: 728 RRVENVKRDVSEIVRGIRFMQRQNENKVKVNKLIAEWRLVGMVLDRLFFVIYLLALGISILLYFPRSGEE 797
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. TrEMBL
Match: G4M0G9 (Acetylcholine-gated chloride channel subunit OS=Schistosoma mansoni OX=6183 GN=ACC-1 PE=2 SV=1) HSP 1 Score: 416.387 bits (1069), Expect = 2.993e-129 Identity = 262/508 (51.57%), Postives = 337/508 (66.34%), Query Frame = 1
Query: 301 IIIGFVFLLKCLRCQYQEKLSIKNHPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVETIKTKQCINP--------SFLNKAP----------PK--HLPSSDFIDKTIQGAQFYDQFYQSNFPQRNQNSNIHYLHSN----HMRNMFESSDVRNSRPNT--PDCAADVP--SVFDRYPTAES 1740
+I+ + L L QY +K WTEK LI +LL Y+KR+RPVVD ++P + N ++QQ+TV FGL LIQI++L+E +QILT +VR+LYRW DYH+ W P Y+NITH++IPT +WLPDI++YNYADER+EERREC + ++G VEWHPMAI+KSTCPV+IKYFP+D+Q C L+FGPWT+D R+NITFYD + +YV + EW ++ K T YPCC E Y D F I ++R +A+YNYILILPCFLLSSLTLVLFWLP E+PAKMVLGMNIF+AFFLL++LLE SIPSASSSFPLIG YYCINMTL+TLSTFLCLI VN HFRGD R EVPFWL+KL + HG+RIL V++G PPP K P +F+ K+P PK +P SDF +K A+ ++F + P N+ + Y ++N HMR+ F + + P PD A++ S F R T E+
Sbjct: 10 LIMFYANFLHPLESQYTDK----------WTEKSLIKDLLRDYEKRARPVVDGMSPEITVG----NTTVQQITVAFGLGLIQILQLNENEQILTVSVRSLYRWTDYHLVWNPEEYENITHINIPTDKIWLPDIALYNYADERLEERRECAVRVDHNGVVEWHPMAIYKSTCPVKIKYFPYDKQVCYLRFGPWTFDSARVNITFYDEGFSM--KDYVESPEWSVLNYWQKHRTHAYPCCPEQYSDTLFFIKIERQAAYYNYILILPCFLLSSLTLVLFWLPPETPAKMVLGMNIFLAFFLLLLLLENSIPSASSSFPLIGNYYCINMTLVTLSTFLCLIVVNLHFRGDRRTEVPFWLRKLALHHGSRILLVNVGPPGGPPPPTSASSNKTSEKPITNMNSVHNFM-KSPDNFLCGDSFNPKMFSVPRSDFTEKFGDNAKV-NRFGK---PHGNKFCSPEYCYANSRQAHMRSQFPTGSPNHKFPGCYYPDNEAEMKHFSQFSRRQTQET 496 HSP 2 Score: 97.0561 bits (240), Expect = 9.362e-17 Identity = 38/70 (54.29%), Postives = 61/70 (87.14%), Query Frame = 1
Query: 2059 RRINLVTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILSLILFFPKAGND 2268
+R+++VT+D+S+I+K + F+QK NE KE+ NKI+SEWRAVG+VLDR FF++Y+ A+ +S++L+FP++G D
Sbjct: 730 KRVHMVTRDVSEIVKGIRFMQKQNEKKEKNNKIISEWRAVGMVLDRLFFIIYLCALGISILLYFPRSGED 799
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Cavefish
Match: chrna4b (neuronal acetylcholine receptor subunit alpha-2 [Source:NCBI gene;Acc:103025036]) HSP 1 Score: 221.476 bits (563), Expect = 5.473e-62 Identity = 133/375 (35.47%), Postives = 218/375 (58.13%), Query Frame = 1
Query: 316 VFLLKCLRCQYQEKLSIKNHPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPP 1440
+ L+ CL+ Y L+ P ++ E+ L+ L + Y+K SRPV N++ V V V FGLS+ Q++ +DE +Q++T+NV W DY +RW P Y+N+T + IP++ +W PDI +YN AD A + +DG ++W P AI+KS+C + + +FPFD+Q CK+KFG WTYD ++++ D+ ++DQ +Y + EW +I K+ T +Y CC E YPDI++ +++R FY LI+PC L+S LT+++F+LP+E K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R +P W+++L ++ R LF +K PP
Sbjct: 9 LVLIICLQHGYVCTLT----PARAHAEERLLQVLFSRYNKLSRPVA-NISDV--------------VLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWSDYKLRWNPEEYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAQLFHDGRIKWKPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDRAKIDLVSMDD--DVDQMDYWESGEWVIINAVGKYNTKKYECCTEIYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECAEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSSRTHRMPHWVRQLFLQLVPRYLF------MKRPP 356
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Cavefish
Match: chrna4b (neuronal acetylcholine receptor subunit alpha-2 [Source:NCBI gene;Acc:103025036]) HSP 1 Score: 216.853 bits (551), Expect = 1.231e-60 Identity = 132/382 (34.55%), Postives = 216/382 (56.54%), Query Frame = 1
Query: 382 KSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVETIKTKQCINPSFLNKAPPKHLPSSDF 1527
++ E+ L+ L + Y+K SRPV N++ V V V FGLS+ Q++ +DE +Q++T+NV W DY +RW P Y+N+T + IP++ +W PDI +YN AD A + +DG ++W P AI+KS+C + + +FPFD+Q CK+KFG WTYD ++++ D+ ++DQ +Y + EW +I K+ T +Y CC E YPDI++ +++R FY LI+PC L+S LT+++F+LP+E K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R +P W+++L ++ R LF +K PP ++ I P PSS +
Sbjct: 24 RAHAEERLLQVLFSRYNKLSRPVA-NISDV--------------VLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWSDYKLRWNPEEYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAQLFHDGRIKWKPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDRAKIDLVSMDD--DVDQMDYWESGEWVIINAVGKYNTKKYECCTEIYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECAEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSSRTHRMPHWVRQLFLQLVPRYLF------MKRPPASGKRNCRKLIEMMHKPVMPQAISPSSQY 382
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Cavefish
Match: chrna2a (cholinergic receptor, nicotinic, alpha 2a (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-2]) HSP 1 Score: 211.075 bits (536), Expect = 4.770e-59 Identity = 144/457 (31.51%), Postives = 239/457 (52.30%), Query Frame = 1
Query: 391 TEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVETIKTKQCINPSFLNKAPPKHLPSSDFIDKTIQGAQFYDQFYQSNFPQRNQNSNIHYLHSNHMRNMFESSDVRNSRPNTPDCAADVPSVFDRYPTAESISGNEEE 1761
E L +L +GY+K SRPV N+T V V V+FGLS+ Q++ +DE +Q++T+NV W DY +RWKP YDN+T + +P++ +W+PDI +YN AD A + + G V W P AI+KS+C + + +FPFD+Q CK+KFG WTYD ++++ +N +L +Y + EW ++ + T +Y CC E YPDI++ +++R FY LI+PC L+S LT+++F+LP++ K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R + ++P W++ + + R LF +K P P +T + LN K +P NQ SN+ S+ ++ + D+ + + +P+ F +PTA S+ +E E
Sbjct: 22 AEDQLFKKLFSGYNKWSRPV-RNITDV--------------VIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYNNADGEFAVTHMTKAHLFHTGKVLWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLERIENTVDL--KDYWESGEWAIVNAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPGWVQSIFLGFIPRWLF------MKRPAPDQTRRRL------LLNAQEKKQVP--------------------------NQTSNLSTSRSSWLQQETD-VDIGRYQDSNGRAGMGIPASFS-FPTATSLHLSESE 421
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Cavefish
Match: ENSAMXT00000019858.2 (neuronal acetylcholine receptor subunit alpha-10 [Source:NCBI gene;Acc:103033580]) HSP 1 Score: 208.764 bits (530), Expect = 5.447e-59 Identity = 131/366 (35.79%), Postives = 209/366 (57.10%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV-DLGFILKTPPPVETIKTKQCINPSFLNKA 1497
L+ +L Y RPV E +I VT++ LS QI+ +DE +QILT+ + W D ++ W YD + + IP+ Y+W PDI +YN AD++ E + +I +DG + W AI KS+C V + +FPFD Q C+L FG WT++G +++I + D ++V NVEWE++ AK + Y CC EPYPDI++ + ++R ++FY + L++PC ++S L + F+LPA+S K+ LG+ + +A + +L+ +S+P S + PLIG YY MT+IT ST L + +N H G + + VP W ++ + + ARI FV ++G T P T T + N F+N++
Sbjct: 23 LLKDLFVNYSNAVRPV-------------EDTDNIINVTLQITLS--QIIDMDERNQILTTYLWIRQVWLDAYLTWNKADYDGLDTIRIPSSYVWRPDIVLYNNADDQFSSSMETNVVIHHDGQIMWDQPAISKSSCKVDVSFFPFDSQKCRLTFGSWTHNGNQMDIL--NGMDSADLADFVENVEWEVLGMPAKKNVILYGCCSEPYPDITYTLQLKRRASFYIFNLLIPCMMISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLLVAESMP-PSENVPLIGKYYIATMTMITASTALTIFIMNIHHCGSDAQPVPEWARRFILNYLARICFVYEVGESCLTVP---TETTSRRGNSCFVNES 367
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Cavefish
Match: chrna10a (cholinergic receptor, nicotinic, alpha 10a [Source:ZFIN;Acc:ZDB-GENE-060503-725]) HSP 1 Score: 208.379 bits (529), Expect = 8.862e-59 Identity = 125/337 (37.09%), Postives = 193/337 (57.27%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTE-LDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
L+N+L Y RPV E I VT++ LS QI+ +DE +QILT+ + W D ++ W YD + + IP Y+W PDI +YN AD+ + + +I+YDG + W I KS+C V + +FPFD Q C+L +G WTY+G +L+I N E D + V NVEWE++ AK ++Y CC +PYPD+++ + ++R ++FY + L++PC ++S L + F+LPA+S K+ LG+ + +A + +L+ + +P S + PLIG YY MT+IT ST L + +N H G + K VP W K +++ ARI FV
Sbjct: 18 LLNDLFRNYTSAMRPV-------------ENTNDILNVTLQITLS--QIIGMDERNQILTAYLWIRQVWTDAYLTWNKDDYDGLDTIRIPGSYVWRPDIVLYNSADDHFTGTMDTNVVIRYDGQIMWDSPIITKSSCKVDVSFFPFDAQQCRLTYGSWTYNGKQLDIL---NALESADLADLVDNVEWEVLGMPAKKNVIQYGCCADPYPDVTYTLKLKRRASFYVFNLLIPCVMISFLAPLGFYLPADSGEKVSLGVTVMLALTVFQLLVAEIMPP-SENVPLIGKYYIATMTMITASTALTIFIMNIHHCGPDAKPVPEWAKTFILQYLARICFV 335
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Sea Lamprey
Match: chrna3 (cholinergic receptor, nicotinic, alpha 3 [Source:ZFIN;Acc:ZDB-GENE-070822-1]) HSP 1 Score: 194.897 bits (494), Expect = 2.356e-54 Identity = 103/299 (34.45%), Postives = 181/299 (60.54%), Query Frame = 1
Query: 514 VTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
V V F +S+ Q++KLDE++QI+ +N+ + W DY +W P ++ + ++ +P+ +W PDI +YN AD + + A++KYDGTV W P AIFKS+C + + YFPFD Q C +KFG WTYD ++++ K L ++ + EW +I ++Y CC + YPDI++ + V+R FY LI+PC L+S LT+++F+LP++ K+ L +++ ++ + ++++ ++IPS S PLIG Y M +TLS + + +N H+R +P W++++ + +I+ +
Sbjct: 33 VIVRFEVSMSQLVKLDEVNQIMATNLWLKHTWNDYKFQWNPGQFEGMEYIRVPSDKIWKPDIVLYNNADGDFQVEGKTKALLKYDGTVMWMPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLVGTKINL--KDFWESGEWVIIDVPGYKHDIKYNCCEQIYPDITYSVYVRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLSISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITIFVLNVHYRTPEAHTMPNWVRRVFLDTLPKIMLL 329
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Sea Lamprey
Match: chrnb3b (cholinergic receptor, nicotinic, beta 3b (neuronal) [Source:ZFIN;Acc:ZDB-GENE-030102-4]) HSP 1 Score: 179.489 bits (454), Expect = 3.310e-49 Identity = 112/342 (32.75%), Postives = 188/342 (54.97%), Query Frame = 1
Query: 394 EKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRA----KFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKE-VPFWLKKLTIKHGARIL 1404
E L+ +L Y K RPV D L+ V V+FGL + Q++ +DE +Q++T+NV W D ++RW P Y I + +P +WLPDI +Y+ AD R E A++K+DG ++W P AI+KS+C + + +FPFD+Q C +KFG WTYDG +++ + +++D+ Y N EWE + + R+ YP I++ +++R FY LI+PC LS LT+ +F+LP++ K+ L ++ ++ + ++++E+ IPS+S PLIG Y M +TLS + + +N H R + + W+++L + +IL
Sbjct: 35 EDRLLKRMLKDYQKWVRPV-DKLS--------------DTVEVKFGLGIAQLVDVDEKNQLMTTNVWLKQEWVDINLRWNPDDYGGINSIRVPASSIWLPDIVLYDNADGRFEGSIVTKAVVKHDGRIKWTPPAIYKSSCTIDVTFFPFDQQNCSMKFGSWTYDGTLVDLIMVN--SDVDRGEYFDNGEWEFLNATGNKGVRLDGHRF------YPYITYSFVIRRLPLFYTLFLIVPCLGLSFLTVFVFYLPSDEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIITVFVINVHHRSSSTHHPMAPWVRQLFLHKLPKIL 353
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Sea Lamprey
Match: chrna2a (cholinergic receptor, nicotinic, alpha 2a (neuronal) [Source:ZFIN;Acc:ZDB-GENE-040108-2]) HSP 1 Score: 173.326 bits (438), Expect = 3.728e-46 Identity = 99/300 (33.00%), Postives = 171/300 (57.00%), Query Frame = 1
Query: 544 QIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPP 1443
+ DE +Q++T+NV W DY ++W P Y+N+T + +P++ +W+PDI +YN AD A + + G V W P AI+KS+C + + +FPFD+Q C +KFG WTYD + I ++D +Y + EW ++ + T +Y CC + YPDI++ +++R FY LI+PC L+S LT+++F+LP++ K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R +P W++++ + R L +++ PPP
Sbjct: 9 HLCDCDEKNQMMTTNVWLKQEWDDYKLQWDPAEYENVTSIRVPSELIWVPDIVLYNNADGDFAVTHMTKAHLFHTGRVRWKPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYD--KAKIDLVSMARDVDLKDYWESGEWAIVHAVGTYNTKKYDCCPQVYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPATHAMPRWVRRVFLDRVPRWL------VMRRPPP 300
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008550.1 (pep scaffold:Pmarinus_7.0:GL476601:34:38373:1 gene:ENSPMAG00000007717.1 transcript:ENSPMAT00000008550.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 157.532 bits (397), Expect = 7.798e-42 Identity = 81/234 (34.62%), Postives = 146/234 (62.39%), Query Frame = 1
Query: 682 LWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTI 1383
+W PDI +YN ADER + + ++ Y G + P + KSTC + +++FPFD Q C LKFG WT+DG+ +++ E D + Y+AN EW+L++ K + Y CC EPYPD+++ + ++R + +Y L++PC L+S+L+L++F LPA+S K+ LG+ + ++ + ++L+ + +P+ S S PLIG Y+ M ++ S + +I + +H + K++P W++ + +
Sbjct: 16 IWTPDILLYNSADERFDATFHTNVLVNYTGNCQHLPPGMLKSTCYIDVRWFPFDVQKCDLKFGSWTHDGWLIDLQML----EADTSGYIANGEWDLVEIPGKRNELYYDCCQEPYPDVTYTLTIRRRTLYYGLNLLVPCVLISALSLLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIGQYFASTMIIVAFSVVVTVIVLQYHHHNPDGKKMPQWVRVILL 245
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Sea Lamprey
Match: chrnb1l (cholinergic receptor, nicotinic, beta 1 (muscle) like [Source:ZFIN;Acc:ZDB-GENE-060811-1]) HSP 1 Score: 138.658 bits (348), Expect = 5.895e-35 Identity = 98/357 (27.45%), Postives = 183/357 (51.26%), Query Frame = 1
Query: 472 YRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFY--DNKTE-----LDQNNYVANVEWELI-KTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPP--PVETIKTKQCINPSFLNKAPPKHL 1512
Y+ + +VTV G++L Q++ L +T + W+D + W P YDN+ + + K +WLPDI++ N D + ++ Y G V W P +I++S+C +++KYFPFD Q C + F +TYD +N+ + +++ E +D++ + + EW++ K K T R P Y DI+F+++++R FY +++PC L++ + F+LP ++ KM L +++ +A + ++LL +P S P+I Y M ++T L +I +N HFR +P+W++++ I + L+++ + P PV T + C + F+ P + L
Sbjct: 37 YKTLVRPARTATGRVTVRLGMTLSQLISLPACQPDMTLSRLISLSWEDPRLSWDPRNYDNLRSIRLSPKRVWLPDIALSNNNDGNFDFGLYVHVLVDYTGAVRWVPPSIYRSSCGMQVKYFPFDWQNCSMVFQSFTYDTSEINLEYALDEHRQEIRHIIIDESTFPVSGEWQIKHKPSRKNTNPRDPL----YQDITFYLIMERKPLFYIINIVVPCILITICAVFTFYLPPDAGEKMGLCISVLLALTVFLLLLADKVPETSLGVPVIVNYLMFTMVIVTACVILTVIVLNLHFRSPATHIMPYWVRRIFIHSLPKYLWIERPKKEELAPKLPVLTQHQQHCHDEYFIRTPPSQAL 389
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Nematostella
Match: EDO42054 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2J7]) HSP 1 Score: 189.889 bits (481), Expect = 1.565e-52 Identity = 120/354 (33.90%), Postives = 190/354 (53.67%), Query Frame = 1
Query: 346 YQEKLSIKNHPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERME---ERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGAR 1398
+ E + + EK L+ +L YD RPV ++ +V VEF LSLIQI+ ++ Q++T +V +W + + W Y I V++ +W+PDI +YN ADE E+ + I DGT EW+ A F STC + ++YFPFD Q C LKFG WTY G RL +T + +L + YV N EW L+ AK V Y CC P+ D++ ++ +QR +Y + LI+PC L+++LTL+ F+LP ES K+ LG+ + +A + ++L+ +++PS S PL+G Y+ M + +S + +NF R + +P W+K + + + AR
Sbjct: 22 FSESSRKRRGASRETAEKRLLADLFRNYDSEVRPVFND---------------SDKVNVEFSLSLIQIIAVNSKSQLVTVSVWIRQKWTNPMLAWNTSKYGGIESVNLNPAKVWIPDIILYNNADETYAGGLEKYKTSVIASSDGTQEWNSPASFTSTCNINVRYFPFDSQNCSLKFGSWTYVGNRLTMTSTSDSADLSK--YVNNGEWHLLAMPAKLNRVFYNCCKYPFYDVTLYLEIQRKPLYYVFNLIIPCALIATLTLIKFFLPPESGEKVGLGITVLLAMTVFLLLVAETLPSTSDHIPLLGQYFVATMFVTAISLVATCLILNFFHRNPSTSPMPHWVKVIILDYMAR 358
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Nematostella
Match: EDO43642 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY59]) HSP 1 Score: 179.489 bits (454), Expect = 1.150e-50 Identity = 110/306 (35.95%), Postives = 174/306 (56.86%), Query Frame = 1
Query: 394 EKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERME---ERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTF 1302
E L+ +L + Y+ RPV+ ++ VTV+ G+SL QI+ LDE +QIL SN+ +W + + W P + N+T +++ +W PD+ +YN AD + +R +K+DG+ W IFKSTC + YFPFD Q C LKFG WTYDG RLNI +N T++ + +V+N EWEL A + Y CC+EPYPD++F + ++R + FY +++PCFL++ LTL+ + LP ES ++ L + +A + ++L+ + +P + PLI YY M ++T+ F
Sbjct: 2 ENKLLKDLFSNYNPSVRPVL---------------KATSSVTVQLGVSLHQIIDLDERNQILISNLWVRQKWNNPLLTWDPTHFGNLTSINVDPLRVWRPDLILYNNADRDTDGALDRFYTKVQLKFDGSSLWLAPIIFKSTCKFDVAYFPFDEQSCILKFGSWTYDGLRLNIV-PENGTDIGIDKFVSNGEWELTGVSANRNVMFYDCCVEPYPDVTFTLKIRRLTLFYYMNMLIPCFLITGLTLLSYILPPESGERITLVVTSLLAQAVYLLLVSEIMPPVAEVVPLISIYYTTAMFMVTVFKF 291
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Nematostella
Match: EDO44896 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUG1]) HSP 1 Score: 178.333 bits (451), Expect = 4.018e-48 Identity = 109/344 (31.69%), Postives = 186/344 (54.07%), Query Frame = 1
Query: 394 EKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERME---ERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFR--GDNRKEVPFWLKKLTIKHGARILFV 1410
E L+ +LL GY+K + PV P+ N++ Q V FGL L+Q++ +D+ +QI+T+NV RW + ++W P Y IT V I +W+PDI +YN AD E+ + I+ +DG W+ A F+STC + + +FPFD+Q C +KFG WT++ L+I + +K+ L + Y+ + EW+LI K Y CC P+ D++ + +R FY + LI+PC +++ + L+ F LP ES ++ L + + +A + + L +++P S + P++G +Y M + LS ++ H + G VP W++ + + +IL V
Sbjct: 12 EHTLLGDLLKGYNKDAHPV-----PIL-------NKT--QYMVTFGLELVQLVNVDDKNQIITTNVWVRQRWTNLLLKWDPDKYGGITRVRIDASKIWIPDIVLYNSADSEFSGGLEKYKTRVILNHDGVNAWYSPASFRSTCQIDVTFFPFDQQTCFMKFGSWTFEVVDLDI--FADKSPLHSSQYMKSAEWDLIAASKKRNVEYYACCTYPFSDVTVTWVFRRKPLFYVFNLIVPCLIITGMVLLGFMLPPESGERITLSITVLLAMAVFLQLAAENLPRNSDNVPVLGIFYITVMVEVALSLIATCYVLHIHHKNSGIAVVPVPHWVQVYMLGYLGKILGV 339
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Nematostella
Match: EDO47969 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKU6]) HSP 1 Score: 170.244 bits (430), Expect = 6.788e-47 Identity = 105/345 (30.43%), Postives = 184/345 (53.33%), Query Frame = 1
Query: 394 EKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERME---ERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRK---EVPFWLKKLTIKHGARILFV 1410
E+ LI++LL GY + +RPV+++ N +++ V FG+ ++QI+ ++ +QI+ +NV RW + + W P Y+ + V + K +W+PDI +Y+ AD E+ + II DG+ W A F+STC + + YFPFD Q C +KFG WTY ++I + + + Y+ + EW+L+ + Y CC EP D++ + ++R FY + LI PC ++ ++ L+ F+LP ES ++ L + + +A + + L+ +++P S S PL+G +Y MT I +S +N H R E+P W+ + ++ A +L V
Sbjct: 1 EQRLISDLLQGYSRNARPVLNS------------NHTLK---VFFGMEIVQIVNVENRNQIIQTNVWIRQRWDNELLTWHPSNYEGVQTVRLDAKSVWIPDIVLYDSADSVFSGGHEKYKTHVIISKDGSSAWFSPASFRSTCKIDVTYFPFDEQTCYMKFGSWTYTIADVDIQ--ASPAPVKSSKYLKSAEWDLMSATTSRKSQIYACCPEPISDVTIAMTIRRKPLFYAFNLITPCMIMLTMILLGFFLPPESGERITLSITVLLAMAVFLQLVAETLPRNSESIPLLGRFYITIMTEIAVSLMATCWVLNIHHRNSGTTLVVEMPKWVDVIVLRWLAVVLCV 328
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Nematostella
Match: EDO40862 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S622]) HSP 1 Score: 161.77 bits (408), Expect = 2.083e-44 Identity = 103/314 (32.80%), Postives = 174/314 (55.41%), Query Frame = 1
Query: 394 EKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADE---RMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNF 1326
E+ L+ +L Y K +RP +++ P V F L QI+ L + +Q+L + +W++ + W P Y + +++ + +W+PDI IYN A++ + + + D +I+ +GT W A+F +TC + ++YFPFD Q C LKFG WT+D RL++ N + +++ Y + EW+L+ K Y CC +PY DIS+ + ++R S FY+ LILP L++S+ LV F LP ES +M LG+ + +A + + + +++PS S S PL+G +Y + M LI+LS I +N+
Sbjct: 1 EQRLLRDLFQNYSKYARPSIESDAPA---------------IVTFRAKLKQIVDLKDNEQLLKIILYNYMQWENPILTWDPRDYGGVQEINVAPEEVWVPDIVIYNSAEDVLGGLTHKYKTDVVIQANGTNIWLAPAMFLTTCQLDVRYFPFDEQKCLLKFGSWTHDSSRLDMRTQTNGS--NKDIYTEHGEWQLVGVEQKRNVKYYDCCPKPYVDISYTVHIRRKSLFYSLYLILPALLITSMVLVGFHLPPESGERMQLGITVLLAMIVFLQFVYQNLPSTSDSAPLLGKFYIVMMFLISLSLGCTCIILNY 297
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Medaka
Match: CHRNA9 (neuronal acetylcholine receptor subunit alpha-9-II-like [Source:NCBI gene;Acc:101173314]) HSP 1 Score: 211.846 bits (538), Expect = 2.563e-60 Identity = 128/336 (38.10%), Postives = 193/336 (57.44%), Query Frame = 1
Query: 403 LINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
L+N+L+ Y RPV E S VT++ LS QI +DE +Q+L + + W D +++W YD + +HIP+ +W PD+ +YN AD+ + + ++Y+G + W AI KS+C V + YFPFD Q C L FG WTY+G +++I Y D +++V NVEWE A + Y CC +PYPDI++ +L+QR S+FY + L+LPCFL+S L + F+LPA+S K+ LG+ + +A + +++ +S+P S S PLIG YY MT++T ST L + +N HF G K VP W K L I + ++I FV
Sbjct: 27 LLNDLMENYSNALRPV-------------EDTDSALNVTLQVTLS--QIKDMDERNQVLIAYLWIRQTWHDAYLKWNKDDYDGLDVIHIPSSLVWRPDLVLYNKADDDFSGPMDTNVKLRYNGEITWDAPAITKSSCVVDVSYFPFDSQECNLTFGSWTYNGNQVDI--YMGMDSGDLSDFVENVEWECHGMPATKNVIMYGCCSDPYPDITYTVLLQRRSSFYIFNLLLPCFLISFLAPLGFYLPADSGEKVSLGVTVLLALTVFQLMVAESMP-PSESVPLIGKYYIATMTMVTASTALTIFIMNIHFCGAEAKPVPHWAKVLIIDYMSKIFFV 344
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Medaka
Match: chrna4b (neuronal acetylcholine receptor subunit alpha-2 [Source:NCBI gene;Acc:101158195]) HSP 1 Score: 214.157 bits (544), Expect = 4.120e-59 Identity = 127/364 (34.89%), Postives = 207/364 (56.87%), Query Frame = 1
Query: 382 KSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVETIKTKQCI 1473
++ E+ L+ L Y+K SRPV NT++ V V FGLS+ Q++ +DE +Q++T+NV W DY +RW P Y+N+T + IP++ +W PDI +YN AD A + YDG ++W P AI+KS+C + + +FPFD+Q CK+KFG WTYD R I +++DQ +Y + EW ++ K+ T +Y CC E Y DI+++ +++R FY LI+PC L+S LT+++F+LP++ K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R +P W++++ + R+LF +K PP K+ I
Sbjct: 41 RAHAEERLLQNLFARYNKLSRPVQ---------NTSD------TVLVHFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWNPEDYENVTSIRIPSEIIWRPDIVLYNNADGDFAVTHLTKAHLFYDGQIKWMPPAIYKSSCSIDVTFFPFDQQSCKMKFGSWTYD--RAKIDLISMASDVDQMDYWESGEWVIVNAVGKYNTKKYECCAEIYADITYYFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSQCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMVFVTLSIIITIFVLNVHHRSPQTHGMPHWVRRVFLDLVPRVLF------MKRPPGTAKQHCKRLI 381
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Medaka
Match: chrna2b (neuronal acetylcholine receptor subunit alpha-2 [Source:NCBI gene;Acc:101155076]) HSP 1 Score: 210.69 bits (535), Expect = 6.921e-59 Identity = 124/340 (36.47%), Postives = 200/340 (58.82%), Query Frame = 1
Query: 391 TEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
E+ L L GY+K SRPV N++ V V V+FGLS+ Q++ +DE +Q++T+NV W DY +RWKP YDN+T + +P++ +W+PDI +YN AD A + + G V W P AI+KS+C + + +FPFD+Q CK+KFG WTYD ++++ +N +L NNY + EW +I + T +Y CC E YPDI++ +++R FY LI+PC L+S LT+++F+LP++ K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R + ++P W+ + + R LF+
Sbjct: 43 AEEELFQTLFTGYNKWSRPV-PNISDV--------------VIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYNNADGEFAVTHMTKAHLFHTGKVRWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLERIENTVDL--NNYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPRWVHTVFLDLIPRWLFM 365
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Medaka
Match: chrna2b (neuronal acetylcholine receptor subunit alpha-2 [Source:NCBI gene;Acc:101155076]) HSP 1 Score: 210.69 bits (535), Expect = 6.921e-59 Identity = 124/340 (36.47%), Postives = 200/340 (58.82%), Query Frame = 1
Query: 391 TEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
E+ L L GY+K SRPV N++ V V V+FGLS+ Q++ +DE +Q++T+NV W DY +RWKP YDN+T + +P++ +W+PDI +YN AD A + + G V W P AI+KS+C + + +FPFD+Q CK+KFG WTYD ++++ +N +L NNY + EW +I + T +Y CC E YPDI++ +++R FY LI+PC L+S LT+++F+LP++ K+ L +++ ++ + ++L+ + IPS S PLIG Y M +TLS + + +N H R + ++P W+ + + R LF+
Sbjct: 43 AEEELFQTLFTGYNKWSRPV-PNISDV--------------VIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYNNADGEFAVTHMTKAHLFHTGKVRWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLERIENTVDL--NNYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPRWVHTVFLDLIPRWLFM 365
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Medaka
Match: chrna10a (neuronal acetylcholine receptor subunit alpha-9-like [Source:NCBI gene;Acc:101158786]) HSP 1 Score: 206.453 bits (524), Expect = 2.872e-58 Identity = 126/339 (37.17%), Postives = 197/339 (58.11%), Query Frame = 1
Query: 397 KVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTE-LDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFV 1410
K L+ +L++ Y K PV E I VT++ LS QI+ +DE +QILT+ + W D H++W +D + + IP Y+W PDI +YN AD+R + + +I++DG + W I KS+C V + +FPFD Q C+ +G WTY+G +L+I N E D + V NVEWE++ AK V Y CC +PYPD++F + ++R ++FY + L++PC ++S L + F+LPA+S K+ LG+ + +A + +L+ + +P S + PLIG YY MT+IT ST L + +N H G + K VP W KK+ +++ AR+ FV
Sbjct: 22 KKLLTDLMSNYTKALIPV-------------EDTNIILNVTLQVTLS--QIIDMDERNQILTAYLWIRQVWFDAHLKWNKEDFDGLDTIRIPGSYVWRPDIVLYNSADDRFTGPMDTNVVIRHDGQMMWDSPYITKSSCKVDVSFFPFDAQQCRFTYGSWTYNGNQLDI---QNAMESADLADLVENVEWEVLGMPAKKNIVLYGCCADPYPDVTFTLKLKRRASFYVFNLLIPCVMISFLAPLGFYLPADSGEKVSLGVTVMLALTVFQLLVAEIMPP-SENVPLIGKYYIATMTMITASTALTIFIMNIHHCGPDAKPVPKWAKKVILQYMARVCFV 341
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Planmine SMEST
Match: SMESG000040082.1 (SMESG000040082.1) HSP 1 Score: 1311.98 bits (3394), Expect = 0.000e+0 Identity = 679/679 (100.00%), Postives = 679/679 (100.00%), Query Frame = 1
Query: 277 MHFHRDQTIIIGFVFLLKCLRCQYQEKLSIKNHPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVETIKTKQCINPSFLNKAPPKHLPSSDFIDKTIQGAQFYDQFYQSNFPQRNQNSNIHYLHSNHMRNMFESSDVRNSRPNTPDCAADVPSVFDRYPTAESISGNEEELDDDLDFRQQQPGNXXXXXXXXXXXXXXXCIQSPIPSQLAASWASYNSAGDFSNSFKQPGHEMGLHSRCQPAFDLKCNPNFEKPILNQHSVAPINVFVARRINLVTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILSLILFFPKAGNDPYYELDNSLNCEISS 2313
MHFHRDQTIIIGFVFLLKCLRCQYQEKLSIKNHPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYILILPCFLLSSLTLVLFWLPAESPAKMVLGMNIFIAFFLLVVLLEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVETIKTKQCINPSFLNKAPPKHLPSSDFIDKTIQGAQFYDQFYQSNFPQRNQNSNIHYLHSNHMRNMFESSDVRNSRPNTPDCAADVPSVFDRYPTAESISGNEEELDDDLDFRQQQPGNYFKEYEEDLEEFLTECIQSPIPSQLAASWASYNSAGDFSNSFKQPGHEMGLHSRCQPAFDLKCNPNFEKPILNQHSVAPINVFVARRINLVTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILSLILFFPKAGNDPYYELDNSLNCEISS
Sbjct: 1 MHFHRDQTIIIGFVFLLKCLRCQYQEKLSIKNHPEKSWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYILILPCFLLSSLTLVLFWLPAESPAKMVLGMNIFIAFFLLVVLLEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLGFILKTPPPVETIKTKQCINPSFLNKAPPKHLPSSDFIDKTIQGAQFYDQFYQSNFPQRNQNSNIHYLHSNHMRNMFESSDVRNSRPNTPDCAADVPSVFDRYPTAESISGNEEELDDDLDFRQQQPGNYFKEYEEDLEEFLTECIQSPIPSQLAASWASYNSAGDFSNSFKQPGHEMGLHSRCQPAFDLKCNPNFEKPILNQHSVAPINVFVARRINLVTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILSLILFFPKAGNDPYYELDNSLNCEISS 679
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Planmine SMEST
Match: SMESG000071641.1 (SMESG000071641.1) HSP 1 Score: 407.527 bits (1046), Expect = 1.558e-132 Identity = 214/344 (62.21%), Postives = 273/344 (79.36%), Query Frame = 1
Query: 385 SWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDL 1416
WTEK+LI +L YDKRSRPVVD ++ + R++ N ++QQ+TVEFG +LIQI+ L+EMDQ+LT++ R+L+RW D ++ W P +Y NI+ V++P LW+PDIS+YNYADER+EERR CDA I DGTV+W PMAI+KSTC V IKYFPFD Q C LKFGPWTYDG+R+NITFY N +D N++ + EW+++ TRA T ++YPCC E YPDI F+I ++R AFY YILILPCFLLSSLTLVLFWLP ESPAKMVLGMNIF+AFFLL++LLE + PSASS+FPLIGTYYC+NM LIT S+F+ + VNFHFRGDN+++VP W+KK+ A++L V L
Sbjct: 17 GWTEKILIRDLFENYDKRSRPVVDGISKLSRVS---ENYTVQQITVEFGFNLIQILDLNEMDQVLTTSTRSLFRWTDPNLVWTPEMYGNISVVNVPADMLWIPDISLYNYADERLEERRSCDAKIYPDGTVDWQPMAIYKSTCSVNIKYFPFDEQTCWLKFGPWTYDGYRVNITFYGNNPNMDLTNFITSPEWKVLATRANHTEIKYPCCPEIYPDIKFYIWIKRQPAFYTYILILPCFLLSSLTLVLFWLPPESPAKMVLGMNIFVAFFLLLLLLEDTTPSASSNFPLIGTYYCLNMGLITFSSFVSCLIVNFHFRGDNKRQVPNWIKKVLFLFIAKLLCVKL 357 HSP 2 Score: 58.151 bits (139), Expect = 2.351e-8 Identity = 26/63 (41.27%), Postives = 40/63 (63.49%), Query Frame = 1
Query: 2074 VTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILSLILFFPKAG 2262
++ I DI+K+L F+Q + +E EW+AVGLV+DR FF Y+ I+LS+ +FP+ G
Sbjct: 484 ISNHIRDIVKNLRFLQNLHHVREISQITEMEWQAVGLVVDRVFFFCYIFIIVLSMASYFPRDG 546
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Planmine SMEST
Match: SMESG000071641.1 (SMESG000071641.1) HSP 1 Score: 388.652 bits (997), Expect = 2.454e-125 Identity = 210/344 (61.05%), Postives = 264/344 (76.74%), Query Frame = 1
Query: 385 SWTEKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDL 1416
WTEK+LI +L YDKRSRPVVD ++ + R++ N ++QQ+TVEFG +LIQI+ L+EMDQ RW D ++ W P +Y NI+ V++P LW+PDIS+YNYADER+EERR CDA I DGTV+W PMAI+KSTC V IKYFPFD Q C LKFGPWTYDG+R+NITFY N +D N++ + EW+++ TRA T ++YPCC E YPDI F+I ++R AFY YILILPCFLLSSLTLVLFWLP ESPAKMVLGMNIF+AFFLL++LLE + PSASS+FPLIGTYYC+NM LIT S+F+ + VNFHFRGDN+++VP W+KK+ A++L V L
Sbjct: 25 GWTEKILIRDLFENYDKRSRPVVDGISKLSRVS---ENYTVQQITVEFGFNLIQILDLNEMDQ----------RWTDPNLVWTPEMYGNISVVNVPADMLWIPDISLYNYADERLEERRSCDAKIYPDGTVDWQPMAIYKSTCSVNIKYFPFDEQTCWLKFGPWTYDGYRVNITFYGNNPNMDLTNFITSPEWKVLATRANHTEIKYPCCPEIYPDIKFYIWIKRQPAFYTYILILPCFLLSSLTLVLFWLPPESPAKMVLGMNIFVAFFLLLLLLEDTTPSASSNFPLIGTYYCLNMGLITFSSFVSCLIVNFHFRGDNKRQVPNWIKKVLFLFIAKLLCVKL 355 HSP 2 Score: 58.151 bits (139), Expect = 2.345e-8 Identity = 26/63 (41.27%), Postives = 40/63 (63.49%), Query Frame = 1
Query: 2074 VTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILSLILFFPKAG 2262
++ I DI+K+L F+Q + +E EW+AVGLV+DR FF Y+ I+LS+ +FP+ G
Sbjct: 482 ISNHIRDIVKNLRFLQNLHHVREISQITEMEWQAVGLVVDRVFFFCYIFIIVLSMASYFPRDG 544
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Planmine SMEST
Match: SMESG000015256.1 (SMESG000015256.1) HSP 1 Score: 288.115 bits (736), Expect = 2.888e-87 Identity = 159/235 (67.66%), Postives = 193/235 (82.13%), Query Frame = 1
Query: 715 ADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKKLTIKHGARILFVDLG 1419
ADER+EERR C A I DGTVEW PMAI+KSTC V IKYFPFD Q C LKFGPWTYDGFR+NITFY+N++ LD ++ V + EW ++++ A T VRYPCC EPYPDISF++ ++R+ FY YILILPCFLLSSLTLVLFW+P ESPAKMVLGMNIF+AFFL+++LL+ + PSAS +FPLIGTYYC+NM +ITLSTFL I VN HFRGDNR+EVP+WLKKL + + L ++LG
Sbjct: 3 ADERLEERRPCAAKISSDGTVEWQPMAIYKSTCFVNIKYFPFDIQTCWLKFGPWTYDGFRVNITFYNNESFLDLSSLVPSPEWTILQSWANHTEVRYPCCDEPYPDISFYVKIRRSPMFYTYILILPCFLLSSLTLVLFWMPPESPAKMVLGMNIFVAFFLMLLLLQDTTPSASRNFPLIGTYYCVNMGIITLSTFLSCIVVNLHFRGDNRQEVPYWLKKLVFNYAVKFLCINLG 237 HSP 2 Score: 78.1814 bits (191), Expect = 1.214e-14 Identity = 34/63 (53.97%), Postives = 46/63 (73.02%), Query Frame = 1
Query: 2074 VTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILSLILFFPKAG 2262
+ KD+ I+K L +IQK ENKE V++I SEWR+VGLVLDR FF Y+ +I S+I++FPK
Sbjct: 473 ICKDVKVIVKSLKYIQKLQENKENVSRIFSEWRSVGLVLDRIFFYCYLFTVIFSIIMYFPKTN 535
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Planmine SMEST
Match: SMESG000069967.1 (SMESG000069967.1) HSP 1 Score: 261.536 bits (667), Expect = 2.512e-77 Identity = 155/327 (47.40%), Postives = 213/327 (65.14%), Query Frame = 1
Query: 394 EKVLINELLNGYDKRSRPVVDNLTPVYRINTAERNQSIQQVTVEFGLSLIQIMKLDEMDQILTSNVRTLYRWKDYHMRWKPHLYDNITHVHIPTKYLWLPDISIYNYADERMEERRECDAIIKYDGTVEWHPMAIFKSTCPVRIKYFPFDRQCCKLKFGPWTYDGFRLNITFYDNKTELDQNNYVANVEWELIKTRAKFTTVRYPCCLEPYPDISFHILVQRNSAFYNYXXXXXXXXXXXXXXXXXXXXAESPAKMVLGMNIFIAXXXXXXXXEKSIPSASSSFPLIGTYYCINMTLITLSTFLCLITVNFHFRGDNRKEVPFWLKK 1374
EK LI ++L Y K+ + I RN V V++GL+LIQIM LDE +QILT NV Y W D + W P + N+ V +P +W PDI +YNYADER+ E+R+ + Y G + W P AIFKSTC + I FPFD Q C LKFG WTY G +L+I Y+N +E+D +Y + EW ++ A+ ++ PD++F ++++RNSA++ Y+L++PC LLS LTLV+FWLP ESPAKM+LGMNIF+AF LL+ LL ++ PSAS+S P +G YYC+NM LITLSTFL +I +N +FR D R+ +P WL+K
Sbjct: 4 EKKLITKMLKDYKKKGK-----------IGRPVRNVQ-DTVVVKYGLALIQIMSLDEKNQILTVNVWAKYTWVDEMLIWNPKNFSNVEEVRMPPDKIWTPDIVLYNYADERLIEKRDVMVSVNYIGRIIWMPPAIFKSTCGIDISNFPFDFQSCYLKFGSWTYKGDKLDIQLYENFSEIDIIDYTESNEWLILHKPARRFVLKNMKDNTSQPDLTFFLILKRNSAYHAYLLVVPCVLLSLLTLVIFWLPPESPAKMILGMNIFVAFSLLLRLLAETTPSASTSVPFLGYYYCLNMILITLSTFLSIIVINLYFRCDKRRNLPDWLRK 318 HSP 2 Score: 55.4546 bits (132), Expect = 1.295e-7 Identity = 28/64 (43.75%), Postives = 40/64 (62.50%), Query Frame = 1
Query: 2071 LVTKDISDIIKDLTFIQKTNENKERVNKIVSEWRAVGLVLDRFFFMLYVIAIILS-LILFFPKA 2259
L+ K++S+I K L + K+R N+I EWR V +VLDR FF +Y + +ILS LIL P+
Sbjct: 471 LLEKNLSEIRKALKNLMTKIAEKDRGNRIAKEWRMVAMVLDRLFFWVYFVIVILSGLILLLPRG 534 The following BLAST results are available for this feature:
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Neuronal acetylcholine receptor subunit alpha-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30021617 ID=SMED30021617|Name=Neuronal acetylcholine receptor subunit alpha-2|organism=Schmidtea mediterranea sexual|type=transcript|length=2544bpback to top protein sequence of SMED30021617-orf-1 >SMED30021617-orf-1 ID=SMED30021617-orf-1|Name=SMED30021617-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=680bp MHFHRDQTIIIGFVFLLKCLRCQYQEKLSIKNHPEKSWTEKVLINELLNGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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